Patent Publication Number: US-2021193289-A1

Title: System for conducting a fluid injection procedure

Description:
CROSS REFERENCE TO RELATED APPLICATIONS 
     This application claims priority to U.S. Provisional Patent Application Ser. No. 62/730,204, entitled “Systems for Conducting a Fluid Injection Procedure”, filed Sep. 12, 2018, the contents of which are incorporated herein by reference. 
    
    
     BACKGROUND OF THE DISCLOSURE 
     Field 
     The present disclosure relates to systems, devices, and/or methods for performing an injection procedure by which fluid(s) in one or more containers are to be administered via a fluid injection system to a patient as part of an imaging procedure. 
     Description of Related Art 
     Contrast media are administered to patients to enhance the contrast of bodily structures or fluids during certain medical procedures. For example, contrast media are used in diagnostic imaging procedures, including X-ray, computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound, and in interventional radiological procedures, such as angioplasty and certain types of chemotherapy. Various forms and concentrations of contrast media are available and are selected based on the type of procedure and the subject of interest. Illustrative contrast media include barium- and iodine-based solutions commonly used in radiological imaging procedures. Contrast media may be delivered to patients through various methods, including ingestion, manual injections, or automated fluid delivery systems. 
     In many medical diagnostic and therapeutic procedures, a physician or other person injects a patient with a fluid. In recent years, a number of injector-actuated syringes and fluid injectors for pressurized injection of medical fluids, such as a contrast solution (often referred to simply as “contrast”), a flushing agent, such as saline, and other medical fluids, have been developed for use in procedures such as angiography, computed tomography (CT), ultrasound, magnetic resonance imaging (MRI), positron emission tomography (PET), and molecular imaging procedures. In general, these fluid injectors are designed to deliver a preset amount of fluid at a preset pressure and/or flow rate. 
     Typically, such powered injectors include a housing allowing one or more syringes to be connected to a front wall thereof. These injectors usually comprise one or two drive members each of which typically featuring a piston that connects to a syringe plunger. A syringe used with a front-loading injector usually includes a readily releasable mounting mechanism for securing the syringe to the front wall of the injector. Such syringes may, for example, include a syringe body, a plunger reciprocally mounted therein, and a plunger extension for transfer of force to the plunger. 
     Such syringes are typically purchased either in a “prefilled” state, containing injection fluid supplied by the manufacturer, or in an empty, “fillable” state. Under current practice, empty syringes are typically attached to or loaded onto the powered injector (either directly or via an adapter as known in the art) and connected via tubing to a source of injection fluid such as a bag or a bottle. The drive member of the powered injector is then reversed to draw the syringe plunger rearward within the syringe, thereby drawing injection fluid from the source into the syringe for later injection into a patient. Thereafter, the powered injector is programmed with the applicable parameters to carry out the appropriate medical procedure. In many medical applications, however, powered injectors are used in procedures and areas in which there are substantial time and access constraints. In time and/or access constrained procedures, the loading of injection fluid into empty syringes using a powered injector and then programming the powered injector to carry out the appropriate fluid injection procedure, results in inefficient use of personnel, equipment, time and/or space. 
     It is, therefore, desirable to develop improved syringe loading/filling devices, improved systems and methods for programming powered injectors, and systems and methods to improve the efficiency of use of personnel, equipment, time and/or space. 
     SUMMARY 
     In accordance with one aspect of the present disclosure, provided is a system for conducting a fluid injection procedure. The system comprises: (a) a container loading system comprising a loading device for filling one or more containers with fluid; (b) an information read/write device operatively associated with the loading device and configured to: read information related to the one or more containers stored on one or more information storage devices associated with the one or more containers; and write information related to at least one of an injection procedure and a patient to the one or more information storage devices; and (c) a fluid injector system configured to receive the one or more containers after filling by the container loading system and inject contents of the one or more containers of fluid into the patient. The loading device is configured to fill the one or more containers with fluid based on the information related to the one or more containers read from the one or more information storage devices by the information read/write device. The information read/write device is configured to write the information related to at least one of the injection procedure and the patient to the information storage device as the loading device is filling the one or more containers with fluid. The fluid injector system is configured to read the information related to at least one of the injection procedure and the patient from the one or more information storage devices when the one or more containers are received by the fluid injector system and the information related to at least one of the injection procedure and the patient is used to program the fluid injector system to conduct the injector procedure. 
     In some non-limiting embodiments or aspects, the one or more containers of fluid may include a container of contrast media and a container of saline. The container of contrast media and the container of saline may be coupled together via a collar. The one or more information storage devices may be provided on the collar. The removal of the collar from the container of contrast media and the container of saline removes information stored on the one or more information storage devices, thereby allowing the collar to be reused. Alternatively, the container of contrast media and the container of saline may be coupled together via a faceplate. The faceplate may be configured to removably engage both the container loading system and the fluid injector system. The one or more information storage devices may be provided in the faceplate. In addition, the faceplate may include a display device for displaying at least one of: information regarding the patient or information regarding a fluid injection procedure. 
     In other non-limiting embodiments or aspects, the information related to the one or more containers stored on the one or more information storage devices may comprise at least one of the following items: (i) a type of the contrast media, (ii) a concentration of the contrast media, (iii) a manufacturer of the contrast media, (iv) a lot number of the contrast media, (v) a serial number of the contrast media, (vi) a manufacturer instructions for the contrast media, (vii) a creation date of the contrast media, (viii) an expiration date of the contrast media, and (ix) a size of the one or more containers. The information related to the one or more containers stored on the one or more information storage devices may be generated by the manufacturer or supplier of the fluid contained in the one or more containers. The information related to at least one of the injection procedure and the patient written to the one or more information storage devices may include at least one of: (i) a pressure and a flow rate to be used by the fluid injector system, (ii) patient weight information, (iii) patient height information, (iv) patient age information, (v) patient name information, (vi) hospital information, (vii) department information, (viii) doctor information, (ix) medical procedure information, (x) medical imaging information, and (xi) automated injection information. 
     In still other non-limiting embodiments or aspects, the information read/write device may be an RFID read/write device and the one or more information storage devices are RFID tags. Alternatively, the information read/write device may be a barcode reader and a barcode printer and the one or more information storage devices are barcode labels. The barcode reader may be configured to read information related to the one or more containers stored on one or more bar code labels associated with the one or more containers; and the barcode printer may be configured to print bar code labels including information related to at least one of the injection procedure and the patient. 
     In accordance with another aspect of the present disclosure, provided is a system for conducting a fluid injection procedure. The system comprises: (a) a container loading system comprising a loading device for filling one or more containers with fluid; (b) a data entry system associated with the loading device and configured to allow entry of at least one of information related to the one or more containers; information related to at least one of an injection procedure; and information related to a patient; (c) a controller operatively connected to the loading device and the data entry system and configured to receive at least one of the information related to the one or more containers; the information related to at least one of the injection procedure; and the information related to the patient and associate at least one of the information related to the one or more containers; the information related to at least one of the injection procedure; and the information related to the patient with the one or more containers as the loading device is filling the one or more containers with fluid; (d) a communication device operatively connected to the controller and configured to transmit at least one of the information related to the one or more containers; the information related to at least one of the injection procedure; and the information related to the patient; and (e) a fluid injector system configured to: receive at least one of the information related to the one or more containers; the information related to at least one of the injection procedure; and the information related to the patient from the communication device; and associate at least one of the information related to the one or more containers; the information related to at least one of the injection procedure; and the information related to the patient with the one or more containers when the one or more containers are mounted to the fluid injector system. 
     In some non-limiting embodiments or aspects, at least one of the information related to the one or more containers, the information related to at least one of the injection procedure, and the information related to the patient is associated with the one or more containers as the loading device is filling the one or more containers with fluid by at least one of: (i) assigning the one or more containers with a unique code that can be entered into the fluid injector system, and (ii) storing at least one of the information related to the one or more containers, the information related to at least one of the injection procedure, and the information related to the patient on a data storage device provided on the one or more container. The data storage device may be one of an RFID tag and a barcode label. 
     In other non-limiting embodiments or aspects, the information related to the one or more containers may comprise at least one of the following items: (i) a type of the contrast media, (ii) a concentration of the contrast media, (iii) a manufacturer of the contrast media, (iv) a lot number of the contrast media, (v) a serial number of the contrast media, (vi) a manufacturer instructions for the contrast media, (vii) a creation date of the contrast media, (viii) an expiration date of the contrast media, and (ix) a size of the one or more containers. The information related to the one or more containers may be generated by the manufacturer or supplier of the fluid contained in the one or more containers. In addition, the information related to the injection procedure and information related to the patient may comprises at least one of: (i) a pressure and a flow rate for the fluid injector system, (ii) patient weight information, (iii) patient height information, (iv) patient age information, (v) patient name information, (vi) hospital information, (vii) department information, (viii) doctor information, (ix) medical procedure information, (x) medical imaging information, and (xi) automated injection information 
     In still other non-limiting embodiments or aspects, the one or more containers of fluid may include a container of contrast media and a container of saline. The communication device may comprise a communication port configured to provide one or more communication methods selected from the group consisting of: Ethernet, wireless protocols, serial, universal serial bus (USB), parallel port, and Bluetooth. The communication device may be configured to transmit at least one of (i) the information related to the one or more containers, (ii) the information related to at least one of the injection procedure, and (iii) the information related to the patient to one or more of: (A) a personal computing device, (B) a server, (C) a distributed computing system, (D) a mobile computing device, (E) a picture archiving and communication system (PACS), (F) a healthcare information and management systems (HIMS), (G) an electronic medical record (EMR) system, (H) a radiology information system (RIS), and (I) a contrast information management system. 
     In accordance with some examples or aspects, the disclosure of the present application may be characterized by one or more of the following numbered clauses: 
     Clause 1: A system for conducting a fluid injection procedure, the system comprising: (a) a container loading system comprising a loading device for filling one or more containers with fluid; (b) an information read/write device operatively associated with the loading device and configured to: read information related to the one or more containers stored on one or more information storage devices associated with the one or more containers; and write information related to at least one of an injection procedure and a patient to the one or more information storage devices; and (c) a fluid injector system configured to receive the one or more containers after filling by the container loading system and inject contents of the one or more containers of fluid into the patient, wherein (i) the loading device is configured to fill the one or more containers with fluid based on the information related to the one or more containers read from the one or more information storage devices by the information read/write device; (ii) the information read/write device is configured to write the information related to at least one of the injection procedure and the patient to the information storage device as the loading device is filling the one or more containers with fluid; and (iii) the fluid injector system is configured to read the information related to at least one of the injection procedure and the patient from the one or more information storage devices when the one or more containers are received by the fluid injector system and the information related to at least one of the injection procedure and the patient is used to program the fluid injector system to conduct the injector procedure. 
     Clause 2: The system of clause 1, wherein the one or more containers of fluid includes a container of contrast media and a container of saline. 
     Clause 3: The system of clause 2, wherein the container of contrast media and the container of saline are coupled together via a collar. 
     Clause 4: The system of clause 2 or clause 3, wherein the one or more information storage devices are provided on the collar. 
     Clause 5: The system of clauses 2-4, wherein removal of the collar from the container of contrast media and the container of saline removes information stored on the one or more information storage devices, thereby allowing the collar to be reused. 
     Clause 6: The system of clause 2, wherein the container of contrast media and the container of saline are coupled together via a faceplate. 
     Clause 7: The system of clause 2 or clause 6, wherein the faceplate is configured to removably engage both the container loading system and the fluid injector system. 
     Clause 8: The system of clause 2, clause 6, or clause 7, wherein the one or more information storage devices are provided in the faceplate. 
     Clause 9: The system of clause 2 or clauses 6-8, wherein the faceplate comprises a display device for displaying at least one of: information regarding the patient or information regarding a fluid injection procedure. 
     Clause 10: The system of clauses 1-9, wherein the information read/write device is an RFID read/write device and the one or more information storage devices are RFID tags. 
     Clause 11: The system of clauses 1-10, wherein the information related to the one or more containers stored on the one or more information storage devices comprises at least one of the following items: (i) a type of the contrast media; (ii) a concentration of the contrast media; (iii) a manufacturer of the contrast media; (iv) a lot number of the contrast media; (v) a serial number of the contrast media; (vi) a manufacturer instructions for the contrast media; (vii) a creation date of the contrast media; (viii) an expiration date of the contrast media; and (ix) a size of the one or more containers. 
     Clause 12: The system of clause 11, wherein the information related to the one or more containers stored on the one or more information storage devices is generated by the manufacturer or supplier of the fluid contained in the one or more containers. 
     Clause 13: The system of clauses 1-12, wherein the information related to at least one of the injection procedure and the patient written to the one or more information storage devices comprises at least one of: (i) a pressure and a flow rate to be used by the fluid injector system; (ii) patient weight information; (iii) patient height information; (iv) patient age information; (v) patient name information; (vi) hospital information; (vii) department information; (viii) doctor information; (ix) medical procedure information; (x) medical imaging information; and (xi) automated injection information. 
     Clause 14: The system of clauses 1-13, wherein the information read/write device is a barcode reader and a barcode printer and the one or more information storage devices are barcode labels. 
     Clause 15: The system of clause 14, wherein the barcode reader reads information related to the one or more containers stored on one or more bar code labels associated with the one or more containers; and the barcode printer prints bar code labels including information related to at least one of the injection procedure and the patient. 
     Clause 16: A system for conducting a fluid injection procedure, the system comprising: (a) a container loading system comprising a loading device for filling one or more containers with fluid; (b) a data entry system associated with the loading device and configured to allow entry of at least one of information related to the one or more containers; information related to at least one of an injection procedure; and information related to a patient; (c) a controller operatively connected to the loading device and the data entry system and configured to receive at least one of the information related to the one or more containers; the information related to at least one of the injection procedure; and the information related to the patient and associate at least one of the information related to the one or more containers; the information related to at least one of the injection procedure; and the information related to the patient with the one or more containers as the loading device is filling the one or more containers with fluid; (d) a communication device operatively connected to the controller and configured to transmit at least one of the information related to the one or more containers; the information related to at least one of the injection procedure; and the information related to the patient; and (e) a fluid injector system configured to: receive at least one of the information related to the one or more containers; the information related to at least one of the injection procedure; and the information related to the patient from the communication device; and associate at least one of the information related to the one or more containers; the information related to at least one of the injection procedure; and the information related to the patient with the one or more containers when the one or more containers are mounted to the fluid injector system. 
     Clause 17: The system of clause 16, wherein at least one of the information related to the one or more containers; the information related to at least one of the injection procedure; and the information related to the patient is associated with the one or more containers as the loading device is filling the one or more containers with fluid by at least one of: assigning the one or more containers with a unique code that can be entered into the fluid injector system; and storing at least one of the information related to the one or more containers; the information related to at least one of the injection procedure; and the information related to the patient on a data storage device provided on the one or more container. 
     Clause 18: The system of clause 17, wherein the data storage device is one of an RFID tag and a barcode label. 
     Clause 19: The system of clauses 16-18, wherein the information related to the one or more containers comprises at least one of the following items: (i) a type of the contrast media; (ii) a concentration of the contrast media; (iii) a manufacturer of the contrast media; (iv) a lot number of the contrast media; (v) a serial number of the contrast media; (vi) a manufacturer instructions for the contrast media; (vii) a creation date of the contrast media; (viii) an expiration date of the contrast media; and (ix) a size of the one or more containers. 
     Clause 20: The system of clause 19, wherein the information related to the one or more containers is generated by the manufacturer or supplier of the fluid contained in the one or more containers. 
     Clause 21: The system of clauses 16-20, wherein the information related to the injection procedure and information related to the patient comprises at least one of: (i) a pressure and a flow rate for the fluid injector system; (ii) patient weight information; (iii) patient height information; (iv) patient age information; (v) patient name information; (vi) hospital information; (vii) department information; (viii) doctor information; (ix) medical procedure information; (x) medical imaging information; and (xi) automated injection information. 
     Clause 22: The system of clauses 16-21, wherein the one or more containers of fluid includes a container of contrast media and a container of saline. 
     Clause 23: The system of clauses 16-22, wherein the communication device comprises a communication port configured to provide one or more communication methods selected from the group consisting of: Ethernet, wireless protocols, serial, universal serial bus (USB), parallel port, and Bluetooth. 
     Clause 24: The system of clauses 16-23, wherein the communication device is configured to transmit at least one of the information related to the one or more containers; the information related to at least one of the injection procedure; and the information related to the patient to one or more of: a personal computing device; a server; a distributed computing system; a mobile computing device; a picture archiving and communication system (PACS); a healthcare information and management systems (HIMS); an electronic medical record (EMR) system; a radiology information system (RIS); and a contrast information management system. 
     These and other features and characteristics of the device of the present disclosure, as well as the methods of operation and functions of the related elements of structures and the combination of parts and economies of manufacture, will become more apparent upon consideration of the following description and the appended claims with reference to the accompanying drawings, all of which form a part of this specification, wherein like reference numerals designate corresponding parts in the various figures. It is to be expressly understood, however, that the drawings are for the purpose of illustration and description only and are not intended as a definition of the limits of the device of the present disclosure. 
     As used in the specification and the claims, the singular form of “a”, “an”, and “the” include plural referents unless the context clearly dictates otherwise. 
    
    
     
       BRIEF DESCRIPTION OF THE DRAWINGS 
         FIGS. 1A -IC are front views of a container loading device in accordance with the present disclosure during various stages of a syringe loading procedure; 
         FIG. 2  is a schematic block diagram of internal hardware of a computing device in accordance with some embodiments of the present disclosure; 
         FIG. 3  is a rear perspective view of a pair of syringes connected via a collar in accordance with the present disclosure; 
         FIG. 4  is a rear perspective view of the pair of syringes of  FIG. 3  having a patient tubing set connected thereto; 
         FIG. 5  is a rear perspective view of an alternative embodiment of a pair of syringes connected via a collar in accordance with the present disclosure; 
         FIG. 6  is a rear perspective view of the pair of syringes of  FIG. 5  having a patient tubing set connected; 
         FIG. 7  is perspective view of a pair of syringes connected via a collar having a hinge with the hinge provided in an open position in accordance with the present disclosure; 
         FIG. 8  is a perspective view of the pair of syringes of  FIG. 7  with the hinge in the closed position in accordance with the present disclosure; 
         FIG. 9  is a perspective view of a portion of a fluid injection system illustrating a frame having an information read/write device in accordance with the present disclosure; 
         FIG. 10  is a perspective view of a portion of a fluid injection system illustrating a cartridge having an information read/write device in accordance with the present disclosure; 
         FIG. 11  is a perspective view of a portion of an alternative embodiment of a fluid injection system illustrating a frame having an information read/write device in accordance with the present disclosure; 
         FIG. 12  is a bottom perspective view of the portion of the fluid injection system of  FIG. 11 ; 
         FIGS. 13A and 13B  are perspective views of a fluid injection system in accordance with the present disclosure at different stages of a fluid injection procedure; 
         FIG. 14  is a perspective view of an alternative embodiment of a loading device prior to having a pair of syringes and faceplate connected thereto in accordance with the present disclosure; 
         FIG. 15  is a perspective view the loading device of  FIG. 14  having the pair of syringes and faceplate connected thereto; 
         FIG. 16  is a perspective view of fluid injection system prior to having the pair of syringes and faceplate of  FIG. 14  connected thereto; 
         FIG. 17  is a perspective view of the fluid injection system of  FIG. 16  having the pair of syringes and faceplate connected thereto; and 
         FIG. 18  is a schematic view of a system for conducting a fluid injection procedure in accordance with the present disclosure. 
     
    
    
     DETAILED DESCRIPTION 
     For purposes of the description hereinafter, the terms “upper”, “lower”, “right”, “left”, “vertical”, “horizontal”, “top”, “bottom”, “lateral”, “longitudinal”, and derivatives thereof, shall relate to the device of the present disclosure as it is oriented in the drawing figures. However, it is to be understood that the device of the present disclosure may assume various alternative variations, except where expressly specified to the contrary. It is also to be understood that the specific devices illustrated in the attached drawings, and described in the following specification, are simply exemplary embodiments of the device of the present disclosure. Hence, specific dimensions and other physical characteristics related to the embodiments disclosed herein are not to be considered as limiting. 
     As used herein, the terms “communication” and “communicate” refer to the receipt or transfer of one or more signals, messages, commands, or other type of data. For one unit or device to be in communication with one or more other unit or device means that the one unit or device is able to receive data from and/or transmit data to the one or more other unit or device. A communication may use a direct or indirect connection, and may be wired and/or wireless in nature. Additionally, two or more units or devices may be in communication with each other even though the data transmitted may be modified, processed, routed, etc., between the first and second unit or device. For example, a first unit may be in communication with a second unit even though the first unit passively receives data and does not actively transmit data to the second unit. As another example, a first unit may be in communication with a second unit if an intermediary unit processes data from one unit and transmits processed data to the second unit. In non-limiting examples, a communication may occur through one or more wired or wireless connections, such as, through one or more wires, through direct wireless protocols such as Bluetooth, Near Field Communication (NFC), or other radio frequency protocols, and/or through indirect wireless communication such as through a local Wi-Fi network or secure Internet connection. Wireless communication may include, but is not limited to, any communication that does not require direct wired contact between the two communicating units or devices such as via a Wi-Fi network, communication via Bluetooth, NFC, or other conventional wireless system, or other non-wired electromagnetic communication systems. It will be appreciated that numerous other arrangements are possible. 
     The present disclosure relates a fluid injection system including a loading system and a fluid injector. The loading system is for use in loading contrast media and diluent, such as saline, into separate syringes prior to installation of those syringes in the fluid injector via which the injection procedure is to be performed as part of a contrast enhanced imaging procedure. The loading system is capable of writing to one or more information storage devices associated with the syringes on which information pertaining to the syringes, the contrast media and/or diluent therein, the injection procedure, and the patient is to be stored. The fluid injector may be configured as a dual syringe fluid injection system that, upon receiving the syringes, is capable of reading from the one or more information storage devices associated with those syringes the information pertaining to the syringes, the contrast media and/or diluent therein, the injection procedure, and the patient and using such information to program the dual syringe fluid injection system to permit the injection procedure to be performed on the patient. 
     More specifically,  FIGS. 1A-1C  depict an illustrative container loading device  3  according to some embodiments. As shown in  FIGS. 1A-1C , the container loading device  3  is configured to fill one or more containers, such as syringes  5 , with a fluid, such as contrast or saline, from a bulk fluid source  4 ,  6 . The container loading device  3  includes: a housing  11  configured to receive an empty syringe  5  and bulk fluid sources; a user interface  13  configured to allow a user to control the container loading device  3  to fill the syringes  5  and to allow entry of at least one of information related to the syringes  5 , information related to at least one of an injection procedure, and information related to a patient; and an information read/write device  15  configured to: read information related to the syringes  5  stored on one or more information storage devices associated with the syringes  5 ; and write information related to at least one of an injection procedure and a patient to the one or more information storage devices. 
     In some embodiments, the user interface  13  and the information read/write device  15  may be integrally formed with the housing  11  of the container loading device  3 . Alternatively, as discussed with reference to  FIG. 18  hereinafter, these devices may be separate components operatively connected to the container loading device  3 . In addition, some embodiments provide that the user interface  13  may be presented on a display device operatively coupled to a computing device  17 . The computing device  17  may include a processing device  19  and memory  21 . An exemplary computing device  17  that may be integrated into the container loading device  3  to provide the user interface  13  and other features of the container loading device is shown in  FIG. 2 . 
     With reference to  FIG. 2  and with continued reference to  FIGS. 1A-1C , illustrative computing device internal hardware according to some embodiments that may be used to contain or implement program instructions is shown. The computing device  17  may include a bus  23  that serves as the main information highway interconnecting the other illustrated components of the hardware. CPU  19  is the central processing unit of the system, performing calculations and logic operations required to execute a program. CPU  19 , alone or in conjunction with one or more of the other elements disclosed in  FIG. 2 , is an exemplary processing device, computing device or processor as such terms are used within this disclosure. Read only memory (ROM)  25  and random access memory (RAM)  27  constitute exemplary memory devices  21  (i.e., processor-readable non-transitory storage media). 
     A controller  29  interfaces with one or more optional memory devices  31  to the system bus  23 . These memory devices  31  may include, for example, an external or internal DVD drive, a CD ROM drive, a hard drive, flash memory, a USB drive or the like. These various drives and controllers are optional devices. 
     Program instructions, software or interactive modules for providing the interface and performing any querying or analysis associated with one or more data sets may be stored in the ROM  25  and/or the RAM  27 . Optionally, the program instructions may be stored on a tangible computer readable medium such as a compact disk, a digital disk, flash memory, a memory card, a USB drive, an optical disc storage medium, such as a Blu-ray™ disc, and/or other non-transitory storage media. 
     An optional display interface  33  may permit information from the bus  23  to be displayed on the display  35 , which may be part of the user interface  13 , in audio, visual, graphic, or alphanumeric format. Communication with external devices, such as a print device, which may be part of the information read/write device  15 , may occur using various communication ports  37 . An exemplary communication port  37  may be attached to a communications network, such as the Internet or an intranet. 
     The hardware may also include an interface  39  which allows for receipt of data from input devices such as a keyboard  41  or other input device  43  such as a mouse, a joystick, a touch screen, a remote control, a pointing device, a video input device and/or an audio input device. The keyboard  41  and other input devices  43  may also be part of the user interface  13 . 
     Returning to  FIGS. 1A-1C , once the empty syringes  5  and bulk fluid sources  4 ,  6  are provided to the housing  11  of the container loading device  3 , the container loading device fills the syringes  5  with the correct amount of fluids based on information read from the information storage devices. More specifically, empty syringes  5  are attached to or loaded onto the housing  11  of the container loading device  3  and connected via tubing  8  to a bulk fluid source such as a bag  6  or a bottle  4 . Each drive member (not shown) of container loading device  3  is coupled to a plunger of one of the empty syringes  5 . The drive members are then actuated to draw the syringe plungers rearward within the syringes  5 , thereby drawing injection fluid from the sources  4 ,  6  into the syringes  5  for later injection into a patient. As shown in  FIG. 1C , a fluid path set  83  may be fluidly connected with the distal end of the syringes  5  for delivering medical fluid from the syringes  5  to a catheter, needle, or other fluid delivery connection (not shown) inserted into a patient at a vascular access site. The fluid path set  83  may also be primed at this point. During the filling of the syringes  5 , the information read/write device  15  is configured to write information related to at least one of an injection procedure and a patient to the information storage device associated with the syringe  5 . 
     More specifically, the container loading device  3  is configured to fill the syringes  5  with fluid based on the information related to the syringes  5  read from the one or more information storage devices by the information read/write device  5 . Thereafter, the information read/write device  15  is configured to write information related to at least one of the injection procedure and the patient to the information storage device as the container loading device  3  is filling syringes  5  with fluid. As will be discussed in greater detail hereinafter, a fluid injector system is then configured to read the information related to the injection procedure and/or the patient from the information storage device when the syringes  5  are received by the fluid injector system and the information related to the injection procedure and/or the patient is then used to program the fluid injector system to conduct the injector procedure. 
     The information storage device may be any suitable device that may have information written thereto and read therefrom. For example, the information read/write device  15  may be configured as a radiofrequency identification (RFID) read/write device and the one or more information storage devices are RFID tags. The information related to the syringes  5  stored on the one or more information storage devices may include one or more of the following items: (i) a type of the contrast media, (ii) a concentration of the contrast media, (iii) a manufacturer of the contrast media, (iv) a lot number of the contrast media, (v) a serial number of the contrast media, (vi) a manufacturer instructions for the contrast media, (vii) a creation date of the contrast media, (viii) an expiration date of the contrast media, and (ix) a size of the one or more containers. Such information may be generated by the manufacturer or supplier of the fluid contained in the one or more containers. In addition, the information related to the injection procedure and/or the patient written to the one or more information storage devices may include one or more of the following: (i) a pressure and a flow rate for the fluid injector system, (ii) patient weight information, (iii) patient height information, (iv) patient age information, (v) patient name information, (vi) hospital information, (vii) department information, (viii) doctor information, (ix) medical procedure information, (x) medical imaging information, and (xi) automated injection information. 
     Alternatively, the information read/write device  15  may be configured as a barcode reader and a barcode printer and the one or more information storage devices are barcode labels. In such an example, the barcode reader reads information related to syringes  5  stored on one or more bar code labels associated with the syringes  5  and the barcode printer prints bar code labels including information related to at least one of the injection procedure and the patient. 
     In a variety of instances, it may be desirable to connect the syringe  5  for contrast and the syringe  5  for saline. For example, the syringes  5  may be used in a dual-syringe fluid injector designed for the administration of two fluids such as contrast and saline. In such injection systems, the two containers of fluid disclosed herein may take the form of two syringes  5  and those syringes may be coupled together, as shown in  FIGS. 1A-1C, 3, and 4 , via a collar  45 . The information storage device  47 , which may be an RFID tag or barcode, may be removably attached or embedded within the collar  45 . The collar  45  comprises a pair of openings  49  sized and shaped to engage one of the syringes  5  near the base of the syringe  5  and a body member  51  connected between the openings. In one example and as shown in  FIGS. 3 and 4 , the information storage device is attached to or embedded within the body member  51 . In addition, the body member  51  is sized such that the syringes  5  are indexed within the injector so that they are held in the proper orientation and distance for insertion into the injector. In some examples, the information storage device  47  may be provided in a manner that is offset from the center of the body member  51 . In this way, if the syringes are inserted into the fluid injector in the wrong orientation, the information storage device  47  will not be read by the information read/write deice  15 , thereby providing an indication to the user that the syringes have been inserted incorrectly. 
     It is desirable to couple the syringes  5  when using a dual-syringe fluid injector such that the syringes  5  are indexed to the injector so that they are held in the proper orientation and distance for insertion into the injector; allow for a user to quickly and easily install the syringes  5  into and remove them from the injector, and improve workflow by requiring fewer steps for setup of the injection procedure. With reference to  FIGS. 5 and 6 , an alternative embodiment of the collar  45  is illustrated. This embodiment of the collar  45  is the same as the collar illustrated in  FIGS. 3 and 4  in that it engages the syringes  5  near the base of the syringes  5  and includes an information storage device  47 . The difference is that this collar  45  is designed to accommodate syringes of two different sizes. In addition, with reference to  FIGS. 7 and 8 , the body member  51  of the collar  45  may include a hinge  53 , thereby allowing the syringes  5  to fold up next to each other to reduce space for shipping. While various collars  45  are illustrated in  FIGS. 3-8 , these collars are not to be construed as limiting the present disclosure as a variety of other collars and frames may be utilized to connect two syringes into a single component. For instance, additional frame and collar concepts that may have application in the present disclosure are also described in co-filed International Patent Application No. PCT/US2019/______ entitled “Syringe Collar and Frame” filed simultaneously herewith on Sep. 10, 2019, which claims priority to U.S. Provisional Application Ser. No. 62/730,153 filed Sep. 12, 2018 and assigned to Bayer HealthCare LLC, each of which incorporated herein by this reference. 
     With reference to  FIGS. 9-12 , in other examples of the system of the present disclosure the information storage device  47  may be incorporated into other frame structures, such as a tube management system used to manage the tubing connected to the outlet of the syringes  5 . For example, and as shown in  FIG. 9 , a frame structure  55  is provided having the information storage device  47  incorporated therein. The frame structure  55  is designed to connect the outlets of the syringes  5  and manage any associated tubing  57  and associated valves, such as stopcock  59 . Upon installation of the syringes  5  and associated frame structure  55  onto the injection system, a camera  61  provided on the injection system reads the information from the information storage device  47  and transfers the information to the injection system for use in the injection procedure to be carried out on the patient for whom the syringes  5  were prepared. With reference to  FIG. 10 , in an alternative example, rather than using a frame structure  55  for tube management, a cartridge  63  may be utilized. The cartridge includes inlet ports  65  configured to engage the outlets of the syringes  5 , inlet ports  67  coupled to bulk fluid sources  69 ,  71 , and a pair of outlet ports  73  configured to be connected to a suitable disposable fluid path set  75  for connection to a patient. In addition, an information storage device is incorporated or associated with the cartridge  63 . Upon installation of the syringes  5  and cartridge  63  onto the injection system, a camera (not shown) provided on the injection system reads the information from the information storage device and transfers the information to the injection system for use in the injection procedure to be carried out on the patient for whom the syringes  5  were prepared. With reference to  FIGS. 11 and 12 , an alternative frame structure  77  may be utilized and connected between an outlet  79  of syringe  5  and a disposable fluid path set or connector tubes  83 . The frame structure  77  may have an information storage device  47  associated therewith that may be read by a camera  61  associated with the injection. 
     Returning to  FIGS. 1A-1C , any of the above described syringes  5 , whether coupled via a collar or frame structure to another syringe or other structure, such as tubing, may be filled using the container loading device  3 . In the example where a pair of syringes  5  are connected via the collar  45  as shown in  FIG. 3 , an operator can fill the two syringes with the appropriate fluids (e.g., contrast and saline) from bulk fluid sources  4 ,  6  in the appropriate amounts and then program information storage device  47  with both the patient data (e.g., patient name or other identifier) and the injection protocol that is to be carried out on the patient for whom the syringes are being prepared using the container loading system  3 . Optionally, an identifier for the loading device being used to load the syringes as well an identifier for the operator who performed the loading operation may also be programmed into the information storage device  47 . The container loading device  3  may be used to load either brand name or generic syringes with the desired fluids from bulk fluid sources. Use of such bulk fluid sources may permit the fluid(s) to be delivered to patients at a lower cost per injection. The loading device  3  also allows the operator (e.g., in an MRI suite) to fill the syringes in the control room of the imaging suite and store the requisite information (e.g., patient data and the syringe loading parameters) onto the information storage device  47 . 
     During this loading operation, after being programmed with the requisite information, the information storage device  47  will ideally be designed so as to retain the information for at least as long as it is connected to the collar. In addition, information storage device  47  may be designed so that it automatically erases upon being removed from the collar  45  or upon removal of the collar  45  from the syringes  5 . In such instances, the collar  45  and/or the information storage device  47  can be reused. When the syringes  5  are removed from the container loading device, the appropriate connector tubing or fluid path set  83  can then be attached to the syringes  5  before leaving the control room (as shown in  FIG. 1C ). Priming of the tubing can be done either with the loading device  3  or with the injection system. 
     Once the syringes  5  have been filled as described hereinabove, they are transported to the injection system to begin an injection procedure. Various examples of the present disclosure are directed to fluid injection systems for injecting one or more fluids into a patient during an injection procedure. In particular examples, the fluid injection systems of the present disclosure may be used for injection of one or more imaging agents in an imaging procedure, such as, for example, CT scan, MRI, and other radiological imaging procedures. The various examples of the fluid injection systems may comprise an injector assembly comprising at least one syringe port for interfacing with a syringe and be configured to inject one or more medical fluids during an imaging procedure. 
     In specific examples, the fluid injector system may be a front-loading fluid injector system similar to the various examples of the injectors disclosed in U.S. Pat. Nos. 5,383,858, 7,553,294, 7,666,169, 9,173,995, 9,199,033 and in International Patent Application Publication No. WO2016/191485, and in U.S. Patent Application Publication No. 2014/0027009, the disclosures of which are incorporated by reference in their entirety. 
       FIGS. 13A and 13B  illustrate a fluid injection system  101  according to a non-limiting example of the present disclosure. With reference to  FIGS. 13A and 13B , the fluid injection system (hereinafter referred to as “injector  101 ”), such as an automated or powered fluid injector, is adapted to interface with and actuate the syringes  5  connected via the collar  45 . The syringes  5  are desirably independently filled with a medical fluid, such as contrast media having a desired concentration or identity, saline solution, or other desired medical fluids as described hereinabove. The injector  101  may be used during a medical procedure, such as an imaging procedure, to inject the medical fluid into the body of a patient by driving a plunger (not shown) of the at least one of the syringes  5  with at least one piston (not shown) operated by a fluid control device, which may be at least partially internal to the injector  101 . In non-limiting examples, the injector  101  may be a multi-syringe injector, wherein the syringes  5  may be oriented side-by-side or in another arrangement and include plungers separately actuated by respective pistons associated with the injector  101 , and controlled by the fluid control device. In one non-limiting example, two syringes may be arranged in a side-by-side fashion and filled with two different medical fluids, such as a contrast agent and a saline solution, and the injector  101  may be configured to deliver fluid to a patient from one or both of the syringes  5  either sequentially or simultaneously. It will be appreciated that various other arrangements are possible. 
     The injector  101  may have a housing  103  formed from a suitable structural material, such as plastic, a composite material, and/or metal. The housing  103  may be of various shapes and sizes depending on the desired application. For example, the injector  101  may be a freestanding structure having a support portion connected to a base with one or more rollers or wheels such that the injector  101  is movable over the floor. In other examples, the injector  101  may have smaller design for placement on a suitable table or support frame. The injector  101  may include a pair of syringe ports  105  for releasably connecting the syringes  5  to respective piston elements. In various examples, the syringes  5  each include at least one syringe retaining member (not shown) configured for retaining the syringes  5  within the respective syringe port  105  of the injector  101 . In non-limiting examples, the at least one syringe retaining member is configured to operatively engage a locking mechanism provided on or in the syringe port  105  of the injector  101  to facilitate self-oriented loading and/or removal of the syringes  5  to and from the injector  101 . The syringe retaining member and the locking mechanism together define a connection interface for connecting the syringes  5  to the injector  101 . 
     In non-limiting examples, at least one fluid path set  83  may be fluidly connected with the distal end of the syringes  5  for delivering medical fluid from the syringes  5  to a catheter, needle, or other fluid delivery connection (not shown) inserted into a patient at a vascular access site. Fluid flow from the syringes  5  may be regulated by a fluid control module operated by a controller. The fluid control module may operate various, pistons, valves, and/or flow regulating devices to regulate the delivery of the medical fluid, such as saline solution and contrast, to the patient based on one or more user selected injection parameters, such as injection flow rate, duration, total injection volume, and/or ratio of contrast media and saline. In one example, the injection parameters may be automatically provided to the fluid control module when the syringes  5  are installed on the injector  101 . More specifically, upon installation of the syringes  5  and associated collar  45  onto the injector  101  as best shown in  FIG. 13B , the drive member (not shown) of the injector engages the plungers of the syringes  5 . If the syringes  5  are installed incorrectly or if syringes of a wrong size are installed, the drive members will not be advanced to the correct position and an indication will be provided to the user that the incorrect syringes have been installed. Once the syringes  5  are correctly installed, information from the information storage device  47  may be transferred to the injector  101  by an information read device  107  for use in the injection procedure to be carried out on the patient for whom the syringes  5  were prepared. The information read device  107  may be a camera configured to read and detect a barcode, a QR code, an RFID reader, or any other suitable device depending on the information storage device  47  provided on the collar  45 . Consistent with the foregoing and as discussed hereinabove, the information storage device  47  may be programmed with one or more of the following information: fluid batch number, fluid batch date, contrast type, contrast volume, saline volume, patient name or other identifier, injection protocol to be performed, and whether or not the attached tubing set  83  is primed. 
     With reference to  FIGS. 14-16 , rather than using the frames and collars as discussed hereinabove, the system of the present disclosure may also be implemented utilizing a programmable faceplate  201 . The programmable faceplate  201  is part of the injector  203  and may be configured as a disposable or reusable item. The faceplate  201  includes a body portion  205  having a pair of syringe ports  207  configured to engage and removably secure each of the syringes  5  by the ends thereof. A bottom side  209  is configured to engage and removably secure the faceplate  201  to both a loading device  211  and the injector  203 . In operation, the programmable faceplate  201  is loaded with two empty syringes  5 . The loading device  211  is programmed using either a user interface  213  or from a control room console for the injection and the patient. Specifically, the loading device  211  may be programed with one or more of the following parameters: fluid batch number, fluid batch date, contrast type, contrast volume, saline volume, patient name or other identifier, injection protocol to be performed, and whether or not an attached tubing set will be primed. Thereafter, the faceplate  201 , along with the syringes  5 , is secured to the loading device  211  and the syringes  5  are filled with the appropriate fluid. At this point, a tubing set may be installed and primed. The faceplate  201  further includes electronics to record the patient information, the fill volumes, and the protocol from the loading device  211 . Alternatively, the faceplate  201  may be provided with a bar code or RFID tag and the loading device  211  would be provided with a corresponding barcode printer or RFID read device to provide the above described information to the faceplate  201 . 
     Once the syringes are filled and the relevant information is transferred to the faceplate  201  as described above, the faceplate  201  and filled syringes  5  are moved from the loading device  211  to the injector  203  as shown in  FIGS. 16 and 17 . At this point, all of the information stored on the faceplate  201  is transferred to the injector  203 . When the drive members are advanced to connect to the plungers, the injector  203 , depending on how it is configured, may be used to verify that the correct syringes are installed by advancing each of the drive members so that each drive member engages its corresponding plunger at an expected plunger position. The injector  203 , at this point, could even automatically arm itself. Configuring the injector  203  in this manner greatly reduces the amount of time that a radiologist, technologist, or other user must spend with the injector  203  in the scan room. In some examples, the faceplate  201  may include an LED display  2013  to display information regarding the patient, such as patient identification number and/or patient name, and information regarding the procedure loaded thereon. 
     With reference to  FIG. 18 , another non-limiting embodiment or aspect of the present disclosure is directed to a system  301  for conducting a fluid injection procedure. The system  301  comprises a container loading system  303  and a fluid injector system  305 . 
     The container loading device  303  includes: a housing  307  configured to receive at least one empty syringe  309  and bulk fluid sources  311 ,  313 ; a user interface  315  configured to allow a user to control the container loading system  303  to fill the syringes  309  and to allow entry of at least one of information related to the syringes  309 , information related to at least one of an injection procedure, and information related to a patient; and an information read/write device  317  configured to: read information related to the syringes  309  stored on one or more information storage devices associated with the syringes  309 ; and write information related to at least one of an injection procedure and a patient to the one or more information storage devices. 
     The information read/write device  317  may be configured to read information associated with the syringes  309  and write information that is to be associated with the syringes  309 . For example, each syringe  309  may be associated with one or more labels. Non-restrictive examples of labels include text-based, RFID, barcodes (one dimensional (1D) and/or two-dimensional (2D)), and QR codes. The information read/write device  317  may be configured to read the information associated with a corresponding type of label and thereafter write information to the label. For instance, information read/write device  317  may include an RFID read/write device configured to read RFID labels and then write information to the labels. In another instance, the information read/write device  317  may include an OCR reader configured to scan text-based labels and provide text information to one or more information consumers (e.g., the user interface  315 ). The information read/write device  317  may further include one or more printers  319  configured to generate labels including barcodes or QR codes to affix to the syringes  309 . Some embodiments provide that information read by the information read/write device  317  may be transmitted within the system  301 . For example, the information from a syringe  309  for use by a patient having a diagnostic imaging exam may be sent to the user interface  315 , a PACS system, and to the fluid injector  305  that will be used to inject the contrast into the patient. In general, information obtained by the information read/write device  317  may be generally available for transmission within the system  301  to electronic devices and computing devices configured to receive and handle the information. 
     In some embodiments, the user interface  315 , the information read/write device  317 , and the printer  319  may be integrally formed with the housing  307  of the container loading system  303 . Alternatively, as shown in  FIG. 18 , these devices may be separate components operatively connected to the container loading system  303 . The user interface  315 , the information read/write device  317 , and the printer  319  together may be considered a data entry system associated with the loading system  303 . Such a data entry system is configured to allow entry of at least one of (i) information related to the syringes  309 , (ii) information related to an injection procedure, and (iii) information related to a patient. 
     The loading system  303  further includes a controller that is operatively connected thereto and to the data entry system. The controller may be any suitable processing device as discussed hereinabove with reference to  FIG. 2 . The controller is configured to receive at least one of (i) the information related to the syringes  309 , (ii) the information related to the injection procedure, and (iii) the information related to the patient and to associate at least one of the (i) information related to the syringes  309 , (ii) the information related to the injection procedure, and (iii) the information related to the patient with the syringes  309  as the loading device is filling the one or more containers with fluid. This information is associated with the syringes  309  as the loading system  303  is filling the syringes  309  with fluid by assigning the syringes  309  a unique code that can be entered into the fluid injector system  305 . Alternatively, this information may be associated with the syringes  309  by storing the information on a data storage device associated with the syringes  309  such that the data storage device is read by the fluid injector system  305  when the syringes  309  are mounted thereto. As discussed hereinabove, the data storage device may be any suitable data storage device such as, but not limited to, an RFID tag or a barcode label. 
     The information related to the syringes  309  may be any one or combination of the following items: (i) a type of the contrast media, (ii) a concentration of the contrast media, (iii) a manufacturer of the contrast media, (iv) a lot number of the contrast media, (v) a serial number of the contrast media, (vi) a manufacturer instructions for the contrast media, (vii) a creation date of the contrast media, (viii) an expiration date of the contrast media, and (ix) a size of the one or more containers. In addition, the information related to the syringes  309  may be generated by the manufacturer or supplier of the fluid contained in the syringes  309 . 
     The information related to the injection procedure and information related to the patient may be any one or combination of the following items: (i) a pressure and a flow rate for the fluid injector system, (ii) patient weight information, (iii) patient height information, (iv) patient age information, (v) patient name information, (vi) hospital information, (vii) department information, (viii) doctor information, (ix) medical procedure information, (x) medical imaging information, and (xi) automated injection information. 
     The loading system  303  may further include a communication device  321  that is operatively connected to the controller and is configured to transmit at least one of (i) the information related to the syringes  309 , (ii) the information related to the injection procedure, and (iii) the information related to the patient. The communication device  321  may be provided within the housing  307  of the loading system  303  as shown in  FIG. 18  or may be provided externally of the loading system  303 . The communication device  321  may include at least one communication port configured to be connected to one or more networks  323  according to known communication methods. Illustrative and non-limiting examples of communication methods available to the communication device  321  include Ethernet, wireless protocols (e.g., IEEE 802.11g, (WiFi 3), IEEE 802.11n (WiFi 4), IEEE 802.11ac (WiFi 5), IEEE 802.11ax (WiFi 6), etc.) serial, universal serial bus (USB), parallel port, Bluetooth®, and proprietary device protocols 
     As shown in  FIG. 18 , the loading system  303  may be in communication, via the communication device  321 , with a network  323 , including, without limitation, a local area network (LAN), wide area network (WAN), wireless network, and combinations thereof. One or more computing devices may also be connected to the network  323 . Illustrative and non-restrictive examples of computing devices may include personal computing devices  325  (e.g., workstations), servers  327  (e.g., data servers, web servers, distributed computing systems (e.g., cloud computing systems), and information systems), mobile computing devices  329  (e.g., tablet computing devices and smart phones), and the fluid injector system  305 . 
     The fluid injector system  305  is configured to: receive at least one of (i) the information related to the syringes, (ii) the information related to at least one of the injection procedure, and (iii) the information related to the patient from the communication device; and to associate at least one of (i) the information related to the one or more containers, (ii) the information related to at least one of the injection procedure, and (iii) the information related to the patient with the one or more containers when the one or more containers are mounted to the fluid injector system. Based on this information, the fluid injector system  305  is armed and a fluid injection procedure may then be conducted. 
     According to some embodiments, the servers  327  may be part of one or more information systems including, but not limited to, a picture archiving and communication system (PACS), healthcare information and management systems (HIMS), electronic medical record (EMR) systems, radiology information systems (RIS), laboratory information systems (LIS), contrast information management systems, and medical imaging and procedure equipment information systems (e.g., contrast injector systems). Some embodiments provide that the loading device, the network, and/or other information systems may be in communication with various other information platforms, such as the Certegra® Workstation offered by Bayer Healthcare. Such features allow, for example, protocol management and the generation of injection protocols using any of the Certegra® P3T software modules. For example, when used with injection systems such as the MEDRAD® Stellant CT Injection System offered by Bayer, the P3T® Cardiac, P3T® Abdomen and P3T® Pulmonary Angiography modules allow Radiologists to personalize the injection protocols for CT cardiac, pulmonary, and abdomen (liver, pancreas, and kidneys) studies, respectively. In addition to its contrast dose management capabilities, the Certegra® Workstation also enables interaction with the Modality Worklist functionality of various OEM scanners and, via its Manage.Report and Connect.PACS capabilities, transfer of injection protocol and other data to hospital IT systems including the PACS, HIMS, RIS, LIS, EMR, and the speech reporting systems used by Radiologists. 
     The personal computing devices  325  and mobile computing devices  329  may be used to access information and to perform functions within the loading system  303 . For example, a personal computing device  325  may be configured to access a user interface (e.g., similar to the user interface  315 ) to access information and to perform functions associated with the loading device  303 . In this manner, users may remotely access the loading system  303  and/or the user interface  315  associated therewith. 
     While specific embodiments of the present invention have been described in detail, it will be appreciated by those skilled in the art that various modifications and alternatives to those details could be developed in light of the overall teachings of the disclosure. Accordingly, the particular arrangements disclosed are meant to be illustrative only and not limiting as to the scope of the device of the present disclosure which is to be given the full breadth of the claims appended and any and all equivalents thereof.