Patent Publication Number: US-2023139756-A1

Title: Fluid connector system

Description:
CROSS REFERENCE TO RELATED APPLICATIONS 
     This application is a continuation-in-part of U.S. patent application Ser. No. 17/853,811, filed on Jun. 29, 2022, which claims the benefit of U.S. Provisional Application No. 63/217,165, filed Jun. 30, 2021, the entire disclosure of each of these applications being incorporated herein in its entirely by this reference. 
    
    
     BACKGROUND 
     The present disclosure relates generally to medical fluid connectors and, more particularly, to fluid connector systems having valve assemblies that can be coupled together to form a fluid pathway. 
     Medical connections are widely used in fluid delivery systems such as those used in connection with intravenous (IV) fluid lines, blood access, hemodialysis, peritoneal dialysis, enteral feeding, drug vial access, and other procedures. 
     In some instances, the medical connection can become dislodged or disconnected in an unintended manner. For example, medical tubing of an IV set that is coupled to a catheter can become dislodged when an unintended or unexpected forces is exerted upon the catheter, which may exceed the design limitations of the catheter securement method. An unintended or unexpected force can be applied to the tubing and/or catheter when the patient moves or rolls over within a bed, or when the tubing or another portion of an intravenous set become caught on a portion of the bed, such as the railing, or when a patient is panicking, disoriented, or fidgeting to such an extent that the medical tubing is unintentionally or intentionally pulled away from the patient or away from the medical equipment coupled to the tubing. 
     SUMMARY 
     In accordance with at least some embodiments disclosed herein is the realization that unintended dislodgement or disconnection of a medical connection, such as a medical fluid line, can result in injury to a patient or a caregiver, such as by depriving the patient of a medicament, increasing the potential for infection to the patient, and exposing the caregiver to harmful medicaments. 
     Accordingly, aspects of the present disclosure provide a fluid connector system comprising: a first valve assembly comprising: a housing having a first end, a second end, wherein the second end is opposite to the first end, and an inner surface forming a cavity that extends through the second end toward the first end of the housing; a post having a proximal end portion and a distal end portion, wherein the distal end portion of the post extends within the cavity in a direction from the first end of the housing toward the second end of the housing; a fluid passage that extends through the first end of the housing and the post; and a compressible valve positioned in the cavity, the compressible valve having a proximal end portion and a distal end portion, wherein the proximal end portion comprises a resilient member having an inner surface forming a recess, and wherein the distal end portion comprises a head having a slit that extends through the head to the recess; a second valve assembly comprising: a body having a first end, a second end, wherein the second end is opposite to the first end, an inner surface forming a bore that extends through the second end toward the first end of the body, and a fluid passage that extends through the first end of the body to the bore; a valve plug positioned in the bore, the valve plug having a first end, a second end, and a slit that extends through the first and second ends of the valve plug; and wherein, when the first and second valve assemblies are separated from each other, the compressible valve is in a first position with a distal end of the head aligned with the second end of the housing and the distal end portion of the post positioned within the recess, and when the first and second valve assemblies are coupled together, the second end of the body is positioned within the cavity of the housing such that the compressible valve is in a second position with the head biased toward the first end of the housing and the distal end portion of the post extending through the slit of the head of the compressible valve and through the slit of the valve plug, such that the fluid passage of the first valve assembly is fluidly coupled with the fluid passage of the second valve assembly. 
     In some instances, the present disclosure provides methods of providing a fluid connector system, the method comprising: providing a first valve assembly comprising a housing forming a cavity having a post therein and a compressible valve extending around the post; providing a second valve assembly comprising a body forming a bore having a valve plug therein; and inserting a second end of the body into the cavity of the housing such that a head of a compressible valve is biased toward a first end of the housing; and advancing the second end of the body into the cavity of the housing such that a distal end portion of the post extends through a slit of the head of the compressible valve and through a slit of the valve plug to fluidly couple a fluid passage of the first valve assembly and a fluid passage of the second valve assembly, and a protrusion of the housing is positioned between a wall of the body and a first end of the body, wherein engagement of the protrusion against the wall resists retraction of the second valve assembly from the first valve assembly. 
     The present disclosure provides a valve plug for a fluid connector system, the valve plug comprising a first end, a second end, and a longitudinal axis that extends between the first and second ends of the valve plug, an inner surface forming a recess that extends through the first end of the valve plug to a floor between the first and second ends of the valve plug, a slit that extends through the second end of the valve plug and the floor; and a first portion of the inner surface forming a ridge that extends into the recess toward the longitudinal axis, and a second portion of the inner surface forming a ramp wall, the ridge comprising a first engagement surface that extends radially inward, in a direction from the first end of the valve plug toward the longitudinal axis, to an apex of the ridge, and a second engagement surface that extends radially outward from the apex and in a direction away from the longitudinal axis, and the ramp wall extending from the second engagement surface to the floor. 
     In some embodiments of the present disclosure, a fluid connector system comprises a first valve assembly comprising a housing having a first end, a second end, wherein the second end is opposite to the first end, and an inner surface forming a cavity that extends through the second end toward the first end of the housing, a post having a proximal end portion and a distal end portion, wherein the distal end portion of the post extends within the cavity in a direction from the first end of the housing toward the second end of the housing, and a fluid passage that extends through the first end of the housing and the post, and a second valve assembly comprising a body having a first end, a second end, wherein the second end is opposite to the first end, an inner surface forming a bore that extends through the second end toward the first end of the body, and a fluid passage that extends through the first end of the body to the bore, a valve plug positioned in the bore, the valve plug having a first end, a second end, and an inner surface forming a recess that extends through the first end of the valve plug to a floor between the first and second ends of the valve plug, a slit that extends through the second end of the valve plug and the floor, and a first portion of the inner surface forming a ridge that extends into the recess toward a longitudinal axis of the valve plug, and wherein, when the first and second valve assemblies are separated from each other, opposing inner surfaces of the valve plug forming the slit are engaged against each other to resist a fluid flow through the valve plug, and when the first and second valve assemblies are coupled together, the distal end portion of the post extends through the slit and the ridge of the valve plug, such that the fluid passage of the first valve assembly is fluidly coupled with the fluid passage of the second valve assembly, and the ridge is engaged against the post to resist movement of a fluid between the post and the ridge. 
     Accordingly, the present application addresses several operational challenges encountered in prior fluid connections and provides numerous improvements that enable the user to increase safety and efficacy, while more easily and precisely providing fluid connections. 
     Additional features and advantages of the subject technology will be set forth in the description below, and in part will be apparent from the description, or may be learned by practice of the subject technology. The advantages of the subject technology will be realized and attained by the structure particularly pointed out in the written description and embodiments hereof as well as the appended drawings. 
     It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory and are intended to provide further explanation of the subject technology. 
    
    
     
       BRIEF DESCRIPTION OF THE DRAWINGS 
       Various features of illustrative embodiments of the inventions are described below with reference to the drawings. The illustrated embodiments are intended to illustrate, but not to limit, the inventions. The drawings contain the following figures: 
         FIG.  1    illustrates a fluid connector system in use with an IV set coupled to a patient, in accordance with aspects of the present disclosure. 
         FIG.  2    illustrates a perspective view of a fluid connector system, in accordance with aspects of the present disclosure. 
         FIGS.  3 A and  3 B  illustrate perspective views of the fluid connector system of  FIG.  2   , in accordance with aspects of the present disclosure. 
         FIG.  4    illustrates a cross-sectional view of the fluid connector system of  FIGS.  3 A and  3 B , in accordance with aspects of the present disclosure. 
         FIG.  5    illustrates a cross-sectional view of the fluid connector system of  FIG.  2   , in accordance with aspects of the present disclosure. 
         FIG.  6    illustrates a cross-sectional view of another embodiment of a fluid connector system, in accordance with aspects of the present disclosure. 
         FIG.  7    illustrates a perspective view of another embodiment of a fluid connector system, in accordance with aspects of the present disclosure. 
         FIGS.  8 A and  8 B  illustrate perspective views of the fluid connector system of  FIG.  7   , in accordance with aspects of the present disclosure. 
         FIG.  9    illustrates a cross-sectional view of the fluid connector system of  FIGS.  8 A and  8 B , in accordance with aspects of the present disclosure. 
         FIG.  10    illustrates a cross-sectional view of the fluid connector system of  FIG.  7   , in accordance with aspects of the present disclosure. 
         FIG.  11    illustrates a perspective view of another embodiment of a valve plug, in accordance with aspects of the present disclosure. 
         FIG.  12    illustrates a top plan view of the valve plug of  FIG.  11   , in accordance with aspects of the present disclosure. 
         FIG.  13    illustrates a bottom plan view of the valve plug of  FIG.  11   , in accordance with aspects of the present disclosure. 
         FIG.  14    illustrates a cross-sectional view of the valve plug of  FIG.  12   , in accordance with aspects of the present disclosure. 
         FIG.  15    illustrates a distribution of force on the valve plug of  FIG.  11    during use, in accordance with aspects of the present disclosure. 
     
    
    
     DETAILED DESCRIPTION 
     In the following detailed description, numerous specific details are set forth to provide a full understanding of the subject technology. It should be understood that the subject technology may be practiced without some of these specific details. In other instances, well-known structures and techniques have not been shown in detail so as not to obscure the subject technology. 
     Further, while the present description sets forth specific details of various embodiments, it will be appreciated that the description is illustrative only and should not be construed in any way as limiting. Additionally, it is contemplated that although particular embodiments of the present disclosure may be disclosed or shown in the context of an IV set, such embodiments can be used in other fluid conveyance systems. Furthermore, various applications of such embodiments and modifications thereto, which may occur to those who are skilled in the art, are also encompassed by the general concepts described herein. 
     In accordance with some embodiments, the present application discloses various features and advantages of a fluid connector system. The fluid connector system can provide for efficient and safe maintenance of fluid connections, such as the connections used for transferring medical fluids toward or away from a patient. The fluid connector system can maintain a fluid pathway by resisting unintended disconnection when a pulling or tension force is applied to the fluid connector system, such as when a patient moves or when the medical tubing is pulled away from the patient. 
     The fluid connector system can also prevent injury to a patient or a caregiver by permitting disconnection or separation between portions of the connector system when a pulling or tension force exceeds a threshold. The fluid connector system can also prevent injury to a patient or a caregiver by obstructing the fluid pathway when disconnection or separation between portions of the connector system occurs. Further, the fluid connector system can provide for efficient and safe reestablishment of the fluid pathway, by permitting reassembly of portions of the system after a disconnection or separation occurs. 
     Referring now to the figures,  FIG.  1    illustrates an example of a fluid connector system in use in accordance with aspects of the present disclosure. The connector system  100  is coupled with tubing of an IV set, which is being used to direct a fluid to a patient  10 . The IV set can include a medicament bag  12 , a drip chamber  14 , tubing  16 , and an IV catheter  18 . 
     The connector system  100  fluidly connects the tubing  16  to the IV catheter  18 . Although the connector system  100  is illustrated being coupled along a fluid pathway of an IV set, between a medicament bag  12  and a patient  10 , it should be understood that the connector system  100  can be connected within other fluid pathways, such as between a patient and a IV pump or between a patient and a dialysis machine. The connector system  100  can also be connected along another portion of a fluid pathway. For example, the connector system  100  can be connected along a proximal portion of the fluid pathway, such as being connected between the tubing  16  and the medicament bag  12  or other fluid therapy device. 
     The connector system  100  includes a first valve assembly  110  and a second valve assembly  210 , which are illustrated in  FIG.  2   . The first and second valve assemblies  110 ,  210  can be coupled together by inserting a portion of the second valve assembly  210  into the first valve assembly  110 . When the first valve assembly  110  and the second valve assembly  210  coupled together, a fluid pathway is formed through the connector system  100 . 
     If any of the first valve assembly  110  and the second valve assembly  210  are pulled away from each other, such as when a pulling or tension force on the connector system  100  exceeds a threshold, the first valve assembly  110  and the second valve assembly  210  can separate from each other. When the first and second valve assemblies  110 ,  210 , separate from each other, as illustrated in  FIGS.  3 A and  3 B , the respective first and second valve assemblies  110 ,  210  can resist a fluid flow therethrough. In some embodiments of the present disclosure, each of the first and second valve assemblies  110 ,  210  can resist fluid flow by obstructing a fluid passage through their respective assemblies. 
     The first valve assembly  110  includes a housing  112  with an inner cavity and a compressible valve  114  positioned in the cavity. When the first valve assembly  110  is not coupled with the second valve assembly  210  or other mating connector, the compressible valve  114  is in a first position, wherein a fluid passage through the first valve assembly  110  is obstructed by the compressible valve  114  to resist fluid flow through the fluid passage of the first valve assembly  110 . 
     When the first valve assembly  110  is coupled with the second valve assembly  210 , the compressible valve  114  is moved to a second position, wherein the fluid passage through the first valve assembly  110  is unobstructed to reduce the resistance to a fluid flow through the fluid passage of the first valve assembly  110 . 
     The second valve assembly  210  includes a body  212  with an inner bore and a valve plug  214  positioned in the bore  220 . When the first valve assembly  110  is not coupled with the second valve assembly  210 , a fluid passage through the second valve assembly  210  is obstructed by the valve plug  214 . 
     When the first and second valve assemblies  110 ,  210  are coupled together, a portion of the first valve assembly  110  moves or biases the valve plug  214  to fluidly couple the fluid passage through the first valve assembly  110  with the fluid passage through the second valve assembly  210 . 
     A cross-sectional view of the connector system  100  is illustrated in  FIGS.  4  and  5   . The first valve assembly  110  includes a housing  112  having a first end  116  and a second end  118 . An inner surface of the housing  112  form a cavity  119  that at extends through the second end  118  toward the first end  116  of the housing. 
     The first valve assembly  110  also includes a post  120  that extends within the cavity and forms at least a portion of a fluid passage through the first valve assembly  110 . The post includes a proximal end portion  122  and a distal end portion  124 , where the distal end portion  124  of the post extends within the cavity in a direction from the first end  116  of the housing toward the second end  118  of the housing. In some embodiments of the present disclosure, the proximal end portion  122  of the post is coupled with the first end  116  of the housing such that the fluid passage  126  of the first valve assembly  110  extends through the first end  116  of the housing and the post  120 . 
     The post  120  includes an inner surface forming a fluid passage  126  that extends through the proximal and distal end portions  122 ,  124  of the post. At the distal end portion  124  of the post, the fluid passage  126  extends through an opening at a distal end  127  of the post. In some embodiments of the present disclosure, the opening for the fluid passage is positioned at a location that is spaced apart from the distal end  127  of the post. 
     In some embodiments of the present disclosure, the post  120  can be configured as a needle that extends within the cavity and forms at least a portion of a fluid passage through the first valve assembly  110 . The post  120  can be formed unitarily with the housing  112  or another portion of the first valve assembly  110 , or the post  120  can be coupled with the housing  112  or another portion of the first valve assembly  110 . In some embodiments, the post  120  is formed from a material that includes any of a polymer and/or a metal. 
     In some aspects of the present disclosure, the housing  112  defines a boss  128  that extends from the first end  116  of the housing in a direction away from the second end  118  of the housing. The boss  128  can include a portion of the fluid passage  126  of the first valve assembly  110 . A cross-sectional width of the fluid passage  126  that extends through the boss  128  can be configured as a bond pocket such that and end of a tubing can be positioned or inserted into the fluid passage  28 . In some embodiments of the present disclosure, the cross-sectional width of the fluid passage  126  that extends through the boss  128  is approximately equal to or greater than a cross-sectional width of the tubing. In some embodiments, tubing can be coupled to the first valve assembly  110  using any of an interference fit and/or creating a bond between the first valve assembly  110  and the tubing. 
     The compressible valve  114  is positioned in the cavity and configured to resist fluid flow through the fluid passage  126  when the compressible valve  114  is in a first position. A fluid flow through the fluid passage  126  is resisted by a portion of the compressible valve  114  positioned between the distal end  127  of the post and the second end  118  of the housing when the compressible valve  114  is in the first position. 
     The compressible valve  114  includes a proximal end portion  132  and a distal end portion  134 . The proximal end portion  132  comprises a resilient member having an inner surface forming a recess  136 . The distal end portion  134  comprises a head  138  defining a distal end  140  of the compressible valve  114 . The head  138  includes a slit  139  that extends through the head  138  to the recess  136 . 
     Although the portion of the compressible valve  114  that forms the resilient member is illustrated as a tube shaped structure having an accordion shaped wall when viewed in cross-section, the resilient member can be formed as any structure that can bias or direct the head  138  toward the second end  118  of the housing. In some embodiments of the present disclosure, the resilient member can be formed by a spring or arms that are positioned between the head  138  and any of the first or second ends  116 ,  118  of the housing. 
     When the compressible valve  114  is in the first position, the distal end  140  of the compressible valve  114  is aligned with the second end  118  of the housing. In some embodiments of the present disclosure, a common plane intersects the distal end  140  of the compressible valve  114  and the second end  118  of the housing when the compressible valve  114  is in the first position. 
     To resist fluid flow through the fluid passage  126 , the first valve assembly  110  is also configured so that the distal end portion  124  of the post is engaged against the head  138 , thereby obstructing the fluid passage  126  of the post. In some embodiments of the present disclosure, the distal most end of the post  120  is positioned within the slit  139  of the head. The head  138  can include a cavity or concave inner surface that extends from the recess  136  toward the distal end  140  of the compressible valve  114 . When the compressible valve  114  is in the first position, the head  138  is engaged against the opening of the fluid passage through the post to resist fluid flow therethrough. 
     When the compressible valve  114  is in the first position, the head  138  of the compressible valve can also engage a protrusion  144  of the housing. The protrusion  144  extends from the inner surface of the housing  112  in a direction into the cavity. In some embodiments of the present disclosure, the protrusion  144  is positioned at the second end  118  of the housing and extends around the perimeter of the inner surface such that, when the compressible valve  114  moves toward the first position, for example, when the head  138  moves toward the second end  118  of the housing, the head  138  engages against the protrusion  144 . 
     In use, when the head  138  moves toward the second end  118  of the housing, engagement of the head  138  against the protrusion  144  can resist movement of the head  138  in the direction from the first end  116  toward the second end  118  of the housing. Engagement of the head  138  against the protrusion  144  can also form a seal between the head  138  and the housing  112 . 
     The first valve assembly  110  is configured to couple with the second valve assembly  210  by inserting a portion of the second valve assembly  210  through the second end  118  of the housing  112  of the first valve assembly  110 . The first valve assembly  110  and the second valve assembly  210  can then be moved toward each other to fluidly couple the first and second valve assemblies  110 ,  210 . 
       FIG.  4    also illustrates a cross-sectional view of the second valve assembly  210  separated from and spaced apart from the first valve assembly  110 . The second valve assembly  210  includes a body  212  having a first end  216  and a second end  218 . An inner surface of the body  212  form a bore  220  that extends through the second end  218  toward the first end  216  of the body. 
     The body  212  also includes a fluid passage  226  that extends through the first end  216  of the body to the bore  220 . The valve plug  214  is positioned in the bore  220  and is configured to obstruct the fluid passage  226  when second valve assembly  210  is not coupled with the first valve assembly  110 . 
     The valve plug  214  includes a first end  236 , a second end  238 , and a slit  240  that extends through the first and second ends  236 ,  238  of the valve plug. The second end  238  of the valve plug is aligned with the second end  218  of the body. In some embodiments of the present disclosure, a common plane intersects the second end  238  of the valve plug and the second end  218  of the body. 
     In some embodiments of the present disclosure, the second end of the body  212  extends radially inward, in a direction toward the cavity. The portion of the body  212  extends radially inward can engage against the valve plug  214  and resist movement of the valve plug  214  out of the bore  220 . 
     In some aspects of the present disclosure, the first end  216  of the body defines a male luer  242  structure that extends in a direction away from the second end  218  and forms at least portion of the fluid passage  226 . In some embodiments of the present disclosure, the first end  116 ,  216  of any of the first and second valve assemblies  110 ,  210  can include any of a bond pocket, a female luer, and/or a male luer. 
     The body  212  forms a wall  244  that is configured to engage against a portion of the first valve assembly  110  when the first and second valve assemblies  110 ,  210  are coupled together. The wall  244  can be formed by a portion of the body  212  that extends away from the outer surface in a direction that is transverse, relative to a longitudinal axis A 2  extending between the first and second ends  216 ,  218  of the body. In some embodiments of the present disclosure, the wall  244  can be formed by a portion of the outer surface of the body  212  that is convex or concave relative to an adjacent portion of the outer surface of the body  212 . 
     The first and second valve assemblies  110 ,  210  can coupled together by inserting the second end  218  of the body for the second valve assembly  210  through the opening into the cavity at the second end  118  of the housing for first valve assembly  110 , as illustrated in  FIG.  5   . 
     When the body  212  is inserted into the cavity and advanced toward the first end  116  of the housing, any of the second end  218  of the body and/or the second end  238  of the valve plug engages against the distal end  140  of the compressible valve. As the second valve assembly  210  is advanced toward the first end  116  of the housing, the resilient member formed by the proximal end portion  132  of the compressible valve is compressed and the head moves toward the first end  116 . Movement of the head  138  toward the first end  116  of the housing causes the distal end portion  124  of the post to move through or pierce the slit  139  of the head and the slit  240  of the valve plug. 
     The body  212  is advanced toward the first end  116  of the housing until the protrusion  144  of the housing moves over and past the wall  244  of the body, such that the protrusion  144  is positioned between the wall  244  and the first end  216  of the body when the first and second valve assemblies  110 ,  210  are coupled together. 
     The distance between the wall  244  and the second end  218  of the body is configured to resist separation of the first and second valve assemblies  110 ,  210 , while maintaining the fluid pathway through the first and second valve assemblies  110 ,  210 . The resist separation and maintaining the fluid pathway, the wall  244  is spaced apart from the second end  218  of the body is by a distance D 1 , where the distance D 2  is approximately equal to or greater than a sum of the length L 1  of the slit  139  and the length L 2  of the slit  240 . 
     When the first and second valve assemblies  110 ,  210  are coupled together, the opening through the distal end  127  of the post is positioned between the valve plug  214  and the first end  216  of the body so that the fluid passage  126  of the first valve assembly  110  is fluidly coupled with the fluid passage  226  of the second valve assembly  210 . 
     In some embodiments of the present disclosure, such as the embodiment illustrated in  FIG.  6   , the opening  141  for the fluid passage is positioned at a location that is spaced apart from the distal end  127  of the post. The opening  141  forms a portion of the fluid passage  126  that extends in a direction that is transverse relative to the longitudinal axis A 2  formed by the fluid passage  126 . For example, the opening  141  at the distal end portion  124  of the post can form a portion of the fluid passage  126  that extend radially outward in a direction that extends away from the longitudinal axis A 2 . 
     The opening can be spaced apart from the distal end  127  of the post and can form a portion of the fluid passage  126  that extends in a directions that is aligned or parallel to the longitudinal axis A 2 . In some instances, the distal end  127  of the post has an outer surface that tapers to form a cross-sectional width that decreases in a direction from the proximal end portion  122  of the post to the distal end  127 , and the opening extends through the tapered outer surface. 
     In some embodiments of the present disclosure, the valve plug  214  can include an inner surface forming a recess  241  that intersects the slit  240 . When the first and second valve assemblies  110 ,  210  are coupled together, the post of the first valve assembly  110  can move through the slit  240  and the recess  241   
     The recess extends into the first end  236  of the valve plug, in a direction toward the second end  238  of the valve plug. The recess  241  can also include a ridge that extends from the inner surface into the recess and in a direction toward the longitudinal axis A 2 . The ridge can be configured to engage against the post  120  of the first valve assembly  110  to form a seal between the ridge of the valve plug  214  and the post  120 . When post  120  is positioned through the valve plug  214 , the ridge can resist movement of a fluid between the valve plug  214  and post  120  out of the bore  220 . 
     Referring to  FIG.  7   , an embodiment of a connector system  400  is illustrated in which a portion of the first valve assembly  410  is received into a sleeve  550  of the second valve assembly  510  when the first and second valve assemblies  410 ,  510  are coupled together. Features of the connector system  400  which are similar to features described with reference to other embodiments herein are not repeated herein for clarity and brevity of the present disclosure. 
     The connector system  400  is illustrated  FIGS.  8 A and  8 B  with the first valve assembly  410  disconnected or separated from the second valve assembly  510 . The first valve assembly  410  includes a protrusion  460  that extends in a direction away from an outer surface of the housing  412 . When the first and second valve assemblies  410 ,  510  are coupled together, the protrusion  460  is inserted into a space between an inner surface of the sleeve  550  and the outer surface of the body  212 . 
     A cross-sectional view of the connector system  100  is illustrated in  FIGS.  9  and  10   . The first valve assembly  410  includes a housing  412  having a first end  416  and a second end  418 . An inner surface of the housing  412  form a cavity that at extends through the second end  418  toward the first end  416  of the housing. 
     The first valve assembly  410  also includes a post  420  that extends within the cavity and forms at least a portion of a fluid passage through the first valve assembly  410 . The post  420  includes a proximal end portion  422  and a distal end portion  424 , where the distal end portion  424  of the post extends within the cavity in a direction from the first end  416  toward the second end  418  of the housing. 
     The post  420  includes an inner surface forming a fluid passage  426  that extends through the proximal and distal end portions  422 ,  424  of the post. At the distal end portion  424  of the post, the fluid passage  426  extends through an opening  421  that is spaced apart from a distal end  427  of the post. In some embodiments of the present disclosure, the opening  421  extends through a portion of the post having an outer surface that tapers to form a cross-sectional width that decreases in a direction away from the proximal end portion  422 . 
     A compressible valve  414  is positioned in the cavity and configured to obstruct the fluid passage  426  when the compressible valve  414  is in a first position. The compressible valve  414  includes a proximal end portion  432  and a distal end portion  434 . Like the compressible valve  114  disclosed with reference to  FIGS.  4  and  5   , the proximal end portion  432  comprises a resilient member and the distal end portion  434  comprises a head  438  having a slit that extends through the head  438  to a recess within resilient member. 
     In some embodiments of the present disclosure, the head  438  comprises an inner surface forming a portion of the recess that extends from the proximal end portion  432  toward the distal end portion  434  of the compressible valve. The recess along the head  438  can be configured so that the head engages against the post to obstruct the opening  421  when the compressible valve is in the first position. 
     The portion of the recess along the head  438  is formed by the inner surface having a cross-section width that is approximately equal to a cross-sectional width of the outer surface of the distal end portion  424  of the post. In some embodiments of the present disclosure, the portion of the recess along the head  438  can have a cross-sectional width that tapers to form a decreasing width in the direction from the proximal end portion  432  toward a distal end  440  of the head  438 . 
     To engage against the post, a first portion  450  of the recess can have a cross-sectional width W 1  that is approximately equal to the cross-sectional width of the outer surface of the post located between the proximal end portion  432  and the opening  421 . A second portion  452  of the recess, located between the first portion  450  of the recess and a distal end  440  of the head, can have a cross-sectional width W 2  that is approximately equal to the cross-sectional width of the outer surface of the post located between the opening  421  and the distal end  427  of the post. 
     When the compressible valve  414  is in a first position, the head  438  is positioned such that the distal end portion  424  of the post is within the recess of the head to resist a fluid flow thought the passage  426  and opening  421  of the post. 
     In some embodiments of the present disclosure, when the compressible valve  414  is in a first position, the inner surface of the head along the first portion  450  of the recess engages against a portion of the post between the proximal end portion  432  and the opening  421 , and the inner surface of the head along the second portion  452  of the recess engages against a portion of the post between the opening  421  and the distal end  427  of the post. 
     When the compressible valve  414  is in the first position, the head  438  of the compressible valve can also engage a ledge  425  of the housing. The ledge  425  ends from the inner surface of the housing  412  in a direction into the cavity. In some embodiments of the present disclosure, the ledge  425  is formed by a portion of the inner surface of the housing having a cross-sectional width that tapers in a direction from the first end  416  toward the second end  418  of the housing. 
     As the compressible valve  414  moves toward the first position, an outer surface of the head  438  can engage against the ledge  425 . In some embodiments of the present disclosure, the outer surface of the head  438  defines a cross-sectional width of the head that tapers so that the cross-sectional width decreases in a direction toward a distal end  440  of the head. 
     The housing  412  also includes a protrusion  460  that is configured to engage against the second valve assembly  510  when the first and second valve assemblies  410 ,  510  are coupled together. The protrusion  460  can be formed by a portion of the housing  412  that extends away from the outer surface in a direction that is transverse, relative to a longitudinal axis A 1  extending between the first and second ends  416 ,  418  of the housing. In some embodiments of the present disclosure, the protrusion  460  can be formed by a portion of the outer surface of the housing  412  that is convex or concave relative to an adjacent portion of the outer surface of the housing  412 . 
     The protrusion  460  is positioned at the second end  418  of the housing, and the ledge  425  is spaced apart from the protrusion  460  along the longitudinal axis A 1 . In some aspects of the present disclosure, the distal end  427  of the post is longitudinally positioned between the ledge  425  and the protrusion  460 . 
     The protrusion  460  is configured to engage against the second valve assembly  510  to resist unintended separation of the first and second valve assemblies  410 ,  510  from each other. The second valve assembly  510  can include a body  512  with an inner bore and a valve plug  514  positioned in the bore  520 . When the first valve assembly  410  is not coupled with the second valve assembly  510 , the valve plug  514  obstructs a fluid passage through the second valve assembly  510 . 
     In some embodiments of the present disclosure, the valve plug  514  includes a groove  515  that extends into an outer surface between the first and second ends of the valve plug. The groove  515  can extend around the circumference of the valve plug and in a direction toward the longitudinal axis A 2  of the second valve assembly  510 . In some aspects, the groove  515  can permit the valve plug  514  to flex or bias when the post  420  is moved through the valve plug  514 . 
     To resist unintended separation of the first and second valve assemblies  410 ,  510  from each other, the second valve assembly  510  includes a sleeve  550 . The sleeve extends along the outer surface of the body  512 , in a direction from the first end  516  toward the second end  518  of the body. In some embodiments, the sleeve  550  extends in a direction that is parallel to a longitudinal axis A 2  extending between the first and second ends  516 ,  518  of the body. 
     The sleeve  550  is spaced apart from the body  512  to permit insertion of a portion of the first valve assembly  410  therebetween. The space between the sleeve  550  and the body  512  is formed between an inner surface of the sleeve  550  and an outer surface of the body  512 . 
     When a portion of the first valve assembly  410  is positioned between the sleeve  550  and the body  512 , engagement of the sleeve  550  and the housing  412  against each other can resist unintended separation of the first and second valve assemblies  410 ,  510  from each other. 
     The portion of the sleeve  550  that engages against the housing  412  can include a wall  544 . The wall  544  extends away from the inner surface of the sleeve in a direction toward the outer surface of the body  512 . In some embodiments of the present disclosure, a distal end of the wall is spaced apart from the outer surface of the body  512  by a distance D 3 . Where the distance D 3  is less that a thickness T 1  of the distal end of the housing  412 , the sleeve can flex or bias away from the outer surface of the body  512  when the second end  418  of the housing  412  to be inserted between the sleeve  550  and the body  512 . 
     A cross-sectional view of the first and second valve assemblies  410 ,  510  coupled together is illustrated in  FIG.  10   . When the body  512  is inserted into the cavity of the housing  412  and advanced toward the first end  416  of the housing, any of the second end  518  of the body and/or the second end  538  of the valve plug engages against the distal end  440  of the compressible valve  414 . 
     As the body  512  and the housing  412  are moved toward each other, the second end  418  of the housing moves into the space between the sleeve  550  and the outer surface of the body  512 . The body  512  and the housing  412  are then moved further toward each other until the protrusion  460  is positioned between the wall  544  and the first end  516  of the body such that engagement of the protrusion  460  against the wall  544  resists unintended separation of the first and second valve assemblies  410 ,  510  from each other. 
     When the body  512  is inserted into the cavity of the housing  412 , and advanced toward the first end  416  of the housing, the fluid passage  426  of the housing becomes fluidly coupled with the fluid passage  526  of the body when the body  512  is advanced into the housing  412  by a distance in which the opening  421  through the distal end portion of the post is positioned between the valve plug  514  and the first end  516  of the body. 
     In some embodiments of the present disclosure, the distal end  427  of the post is longitudinally positioned between the ledge  425  and the protrusion  460  so that, when the first and second valve assemblies  410 ,  510  coupled together, the opening  421  through the distal end portion of the post is positioned between the valve plug  514  and the first end  516  of the body. 
     When the first and second valve assemblies  410 ,  510  are coupled together, a fluid pathway of the connector system  400  is formed by the fluid passage  426  of the first valve assembly  410  and the fluid passage  526  of the second valve assembly  510 . When the first and second valve assemblies  410 ,  510  are disconnected or separated from each other, the compressible valve  414  moves to an unrestrained position so that the head  438  obstructs or resist fluid flow through the post, and the valve plug  514  resists fluid flow through the fluid passage  526 . 
     An embodiment of the valve plug  615  for the connector system is illustrated in  FIGS.  11  to  15   . The valve plug  615  includes features that seal or restrict a fluid pathway through the valve plug when low and high pressures are exerted on the valve. A high fluid pressure can be exerted on the valve when a post  120 ,  420  of a fluid coupling assembly is inserted through the valve plug  615  and a pressure is directed against the valve plug by a fluid from the post or connector system. To resist the formation of an unintended pathway between the post  120 ,  420  and the valve plug  615 , which can result in fluid leakage therebetween, features of the valve plug  615  provide a substantially uniform sealing pressure against the post  120 ,  420  of the fluid coupling assembly. 
     The valve plug  615  includes a first end  636 , a second end  638 , and a slit  640  that extends through the second end  638  of the valve plug an in a direction toward the first end  636  of the valve plug. The slit  640  is formed by inner surfaces of the valve plug  615  and forms a pathway through at least a portion of the valve plug  615 . The slit  640  can permit insertion of a post for a valve assembly therethrough and can close the pathway when a post is not inserted through the valve plug  615 . 
     When the valve plug  615  is in a disconnected state, e.g., no post  120 ,  420  of a fluid coupling assembly extending into the valve plug, the inner surfaces of the valve plug  615  that form the slit  640  are engaged against each other to close or obstruct the pathway through the slit. When the valve plug  615  is in a connected state, e.g., a post  120 ,  420  of a fluid coupling assembly extending into the valve plug, at least a portion of the inner surfaces of the valve plug  615  that form the slit  640  are moved away from each other by insertion of the post therebetween, and the portion of the inner surfaces of the valve plug  615  that form the slit  640  engage against the post to resist movement of a fluid between the post and the valve plug  615 . 
     In some embodiments of the second end  638  of the valve plug includes a recessed or concave surface  639 , illustrated in  FIGS.  11 ,  12 , and  14   , that extends in a direction from the second end  638  toward the first end of the valve plug. The concave surface  639  and slit  640  are aligned relative to each other such that the slit  640  is approximately centered in the concave surface  639 . 
     Referring to  FIGS.  13  and  14   , another portion of the inner surface of the valve plug  615  can form a recess  641  that extends through the first end  636  of the valve plug to a floor  643  between the first and second ends  636 ,  638  of the valve plug. The slit  640  extends through the floor  643  thereby creating a pathway through the slit  640  and the recess  641 , and entirely through the first and second ends  636 ,  638  of the valve plug. 
     The inner surface of the valve plug  615  also forms a ridge  646  that extends radially inward toward a longitudinal axis A 6  defined between the first and second ends  636 ,  638  of the valve plug. The ridge  646  includes a first engagement surface  648  that extends radially inward, in a direction from the first end  636  of the valve plug toward the longitudinal axis A 6 , to an apex  650  of the ridge. A second engagement surface  652  of the ridge extends radially outward from the apex  650 , in a direction away from the longitudinal axis A 6  and toward the floor  643  of the recess. 
     Between the ridge  646  and the floor  643 , the inner surface of the valve plug forms a ramp wall  654 . The ramp wall  654  has a length that extends from a first end of the ramp wall at the second engagement surface  652  of the ridge to a second end of the ramp wall at the floor  643  of the recess. 
     At least a portion of the length of the ramp wall  654  is oriented extending in a direction away from the longitudinal axis A 6 . The ramp wall  654  forms a straight conical surface between the second engagement surface  652  and the floor  643 . In some embodiments of the present disclosure, the entire length of the ramp wall  654  forms a straight conical surface that extends in direction away from the longitudinal axis A 6 . In some embodiments, a portion of the length of the ramp wall  654  can extend in a direction that is parallel to the longitudinal axis A 6  and/or in a direction away from the longitudinal axis A 6 . The present disclosure also contemplates embodiments in which the entire length of the ramp wall  654 , or a portion thereof, forms any of a concave surface extending away from the longitudinal axis A 6 , and a convex surface extending toward the longitudinal axis A 6 . 
     The ridge  646  is configured to engage against a post for a valve assembly that is inserted into the recess  641  the vale plug. In some embodiments of the present disclosure, at least the apex  650  of the ridge can engage against the post to create a seal between the post and the valve plug  615  that resists movement of a fluid therebetween. 
     The ramp wall  654  has a perimeter that extends around or encircles the longitudinal axis A 6 . The perimeter of the ramp wall  654  is configured to extend entirely around the longitudinal axis of the valve plug  615 , thereby forming a toroid shape around the longitudinal axis A 6 . In some instances, embodiments of the present disclosure, the ramp wall  654  is discontinuous along its perimeter. In some embodiments, the discontinuity of the ramp wall  654  can be formed by any of a channel, a groove, a ridge, and/or a dimple formed on the ramp wall  654 . 
     The inner surface of the valve plug  615  defines a width of the recess  641 , transverse relative to the longitudinal axis A 6 , that varies between the first end  636  of the valve plug and the floor  643 . The recess has a first width WR 1  at the apex  650  of the ridge, and the recess has a second width WR 1  at the first end of the ramp wall  654  adjacent to the second engagement surface  652 . The inner surface of the valve plug  615  is formed so that the smallest width of the recess  641  is at the first width WR 1  at the apex  650  of the ridge, and the width at other portions of the recess is greater that the first width WR 1 . 
     The width of the recess  641 , transverse relative to the longitudinal axis A 6 , increases and decreases between the first end  636  of the valve plug and the floor  643 . Along the first engagement surface  648 , the width increases from the first end  636  of the valve plug to the apex  650  of the ridge. Along the second engagement surface  652 , the width of the recess decreases from the apex  650  of the ridge to the ramp wall  654 . Along the ramp wall  654 , the width increases in a direction toward the floor  643 . 
     The recess  641  extends into the valve plug by a total distance DR from the first end  636  of the valve plug to the floor, where the total distance has a first portion DR- 1  and a second portion DR- 2 . The ridge  646  extends along the first portion DR- 1  of the distance of the recess, and the ramp wall  654  extends along the second portion DR- 2  of the distance of the recess. The second portion DR- 2  of the distance of the recess is greater than the first portion DR- 1  of the distance of the recess. In some instance of the present disclosure, the total distance DR from the first end  636  of the valve plug to the floor  643  is less than a distance DS from the second end  638  of the valve plug to the floor  643 . 
     The valve plug  615  provides a fluid pathway that is sealed when the valve plug is in a disconnected state, e.g., no post  120 ,  420  of a fluid coupling assembly extending into the valve plug, and the valve plug provides a substantially uniform sealing pressure when the valve plug is in a connected state, e.g., a post  120 ,  420  of a fluid coupling assembly extending into the valve plug. The uniform sealing pressure provided by the valve plug  615  is illustrated in  FIG.  15   , which shows the magnitude of pressure directed by the slit  640  and the ridge  646  against a post  120 ,  420  of a fluid coupling assembly, where the post  120 ,  420  is omitted in  FIG.  15    for clarity. 
     The pressure directed by the ridge  646  against a post  120 ,  420  of a fluid coupling assembly is uniformly distributed around the entire perimeter of the ridge  646 , thereby resisting movement or leakage of a fluid between the post  120 ,  420  and the ridge  646 . The pressure P 1  exerted by the ridge  646  against the post  120 ,  420  is uniformly distributed around the perimeter of the post  120 ,  420 . The pressure exerted by the ridge is greatest at the apex  650  and decreases in a direction away from the apex  650 , along the first and second engagement surfaces  648 ,  652 . 
     The pressure P 2  exerted by the slit  640  against the post  120 ,  420  is less at a lateral end portion  662  of the slit  640 , relative to the pressure exerted by the slit  640  against the post  120 ,  420  a middle portion  664  of the slit. In some embodiments of the present disclosure, a distance from the apex  650  to the floor  643  of the recess is greater than a distance from the first end  636  of the valve plug to the apex  650 , which provide for the pressure P 2  exerted by the slit  640  against the post  120 ,  420  to be greatest along the second engagement surface  652  of the ridge. 
     When the post  120 ,  420  of a fluid coupling assembly is inserted into the valve plug, a portion of the valve plug forming the slit  640  can move or be deflected into the recess, as shown, for example, in  FIG.  15   . In some embodiments of the present disclosure, the middle portion  664  of the slit is deflected into the recess  641  and at least a portion of the floor  643  is moved into the portion of the recess along the ramp wall  654 , which is identified as the second portion DR- 2  of the distance of the recess in  FIG.  14   . 
     When the post  120 ,  420  of a fluid coupling assembly is withdrawn or otherwise removed from the valve plug  615 , the valve plug is in a disconnected state in which the inner surfaces forming the slit  640  engage against each other to close the fluid pathway through the valve plug  615  and resist movement of a fluid therethrough. 
     In some embodiments of the present disclosure, the valve plug  615  can resist movement of a fluid through the slit  640  in the disconnected state when the fluid pressure is between approximately 1 PSI and approximately 120 PSI. In some embodiments, the valve plug  615  can resist movement of a fluid through the slit  640  in the disconnected state when the fluid pressure is approximately 60 PSI or less. In some embodiments of the present disclosure, the valve plug  615  can resist movement or leakage of a fluid between the post  120 ,  420  and the ridge  646  in the connected state when the fluid pressure is between approximately 1 PSI and approximately 480 PSI. In some embodiments, the valve plug  615  can resist movement or leakage of a fluid between the post  120 ,  420  and the ridge  646  when the fluid pressure is approximately 320 PSI or less. 
     It should be understood that although the present disclosure discloses the valve plug  615  as a single uniform component, the present disclosure contemplates embodiments in which the valve plug  615  is formed by two separate components, where a first component forms the first end  636 , the ridge  646  and the ramp wall  654 , and a second component forms the slit  640  and the second end  638 . The first and second components can be assembled together or bonded together to form the valve plug  615 . In some embodiments of the present disclosure, the first and second components can be positioned in a valve assembly  210 ,  410  such that the first and second components are spaced apart by a distance therebetween. 
     Illustration of Subject Technology as Clauses 
     The subject technology is illustrated, for example, according to various aspects described below. Various examples of aspects of the subject technology are described as numbered clauses (1, 2, 3, etc.) for convenience. These are provided as examples and do not limit the subject technology. It is noted that any of the dependent clauses may be combined in any combination, and placed into a respective independent clause, e.g., clause 1 or clause 5. The other clauses can be presented in a similar manner. 
     Clause 1. Accordingly, aspects of the present disclosure provide a fluid connector system comprising: a first valve assembly comprising: a housing having a first end, a second end, wherein the second end is opposite to the first end, and an inner surface forming a cavity that extends through the second end toward the first end of the housing; a post having a proximal end portion and a distal end portion, wherein the distal end portion of the post extends within the cavity in a direction from the first end of the housing toward the second end of the housing; a fluid passage that extends through the first end of the housing and the post; and a compressible valve positioned in the cavity, the compressible valve having a proximal end portion and a distal end portion, wherein the proximal end portion comprises a resilient member having an inner surface forming a recess, and wherein the distal end portion comprises a head having a slit that extends through the head to the recess; a second valve assembly comprising: a body having a first end, a second end, wherein the second end is opposite to the first end, an inner surface forming a bore that extends through the second end toward the first end of the body, and a fluid passage that extends through the first end of the body to the bore; a valve plug positioned in the bore, the valve plug having a first end, a second end, and a slit that extends through the first and second ends of the valve plug; and wherein, when the first and second valve assemblies are separated from each other, the compressible valve is in a first position with a distal end of the head aligned with the second end of the housing and the distal end portion of the post positioned within the recess, and when the first and second valve assemblies are coupled together, the second end of the body is positioned within the cavity of the housing such that the compressible valve is in a second position with the head biased toward the first end of the housing and the distal end portion of the post extending through the slit of the head of the compressible valve and through the slit of the valve plug, such that the fluid passage of the first valve assembly is fluidly coupled with the fluid passage of the second valve assembly. 
     Clause 2. The fluid connector system of Clause 1, wherein the housing of the first valve assembly comprises a protrusion that extends from the inner surface of the housing in a direction into the cavity. 
     Clause 3. The fluid connector system of Clause 2, wherein the protrusion is proximal to the second end of the housing. 
     Clause 4. The fluid connector system of Clause 2, wherein, when the compressible valve is in the first position, the head of the compressible valve is engaged against the protrusion. 
     Clause 5. The fluid connector system of Clause 2, wherein, an outer surface of the body of the second valve assembly comprises a wall that extends in a direction away from the outer surface in a direction that is transverse, relative to a longitudinal axis extending between the first and second ends of the body. 
     Clause 6. The fluid connector system of Clause 5, wherein, when the first and second valve assemblies are coupled together, the protrusion of the first valve assembly is positioned between the wall and the first end of the body. 
     Clause 7. The fluid connector system of Clause 1, wherein the fluid passage of the first valve assembly comprises an opening through a distal end of the post. 
     Clause 8. The fluid connector system of Clause 1, wherein the fluid passage of the first valve assembly comprises an opening spaced apart from a distal end of the post. 
     Clause 9. The fluid connector system of any of Clauses 1 to 8, wherein the first end of the housing comprises a bond pocket that extends into the first end of the housing in a direction toward the second end of the housing, and wherein the fluid passage of the first valve assembly extends through the bond pocket. 
     Clause 10. The fluid connector system of any of Clauses 1 to 9, wherein the second end of the body extends radially inward in a direction toward the cavity, and wherein, the second end of the valve plug is aligned with the second end of the body. 
     Clause 11. The fluid connector system of any of Clauses 1 to 10, wherein the first end of the body comprises a male luer that extends in a direction away from the second end of the body, and wherein the fluid passage of the second valve assembly extends through the male luer. 
     Clause 12. The fluid connector system of any of Clauses 1 to 11, wherein any of the first end of the housing and the first end of the body comprise any of a bond pocket, a female luer, and/or a male luer. 
     Clause 13. The fluid connector system of any of Clauses 1 to 12, wherein the inner surface of the housing comprises a ledge such that a cross-sectional width of the inner surface of the housing decreases in a direction from the first end toward the second end of the housing. 
     Clause 14. The fluid connector system of Clause 13, wherein the housing comprises a protrusion that extends from an outer surface of the housing in a direction away from the cavity, and wherein, the ledge is spaced apart from the protrusion along a longitudinal axis extending between the first and second ends of the housing. 
     Clause 15. The fluid connector system of Clause 13, wherein, when the compressible valve is in the first position, the head of the compressible valve is engaged against the ledge. 
     Clause 16. The fluid connector system of Clause 14, wherein the second valve assembly comprises sleeve that extends along a longitudinal axis extending between the first and second ends of the body, and in a direction toward the second end of the body, and wherein an inner surface of the sleeve is spaced apart from an outer surface of the body. 
     Clause 17. The fluid connector system of Clause 16, wherein, a wall extends from the inner surface of the sleeve in a direction toward the outer surface of the body. 
     Clause 18. The fluid connector system of Clause 17, wherein, when the first and second valve assemblies are coupled together, the protrusion of the first valve assembly is positioned between the wall and the first end of the body. 
     Clause 19. The fluid connector system of any of Clauses 1 to 18, wherein, when the first and second valve assemblies are coupled together, a fluid can flow from the first valve assembly to the second valve assembly, or from the second valve assembly to the first valve assembly. 
     Clause 20. A method of providing a fluid connector system, the method comprising: providing a first valve assembly comprising a housing forming a cavity having a post therein and a compressible valve extending around the post; providing a second valve assembly comprising a body forming a bore having a valve plug therein; and inserting a second end of the body into the cavity of the housing such that a head of a compressible valve is biased toward a first end of the housing; and advancing the second end of the body into the cavity of the housing such that a distal end portion of the post extends through a slit of the head of the compressible valve and through a slit of the valve plug to fluidly couple a fluid passage of the first valve assembly and a fluid passage of the second valve assembly, and a protrusion of the housing is positioned between a wall of the body and a first end of the body, wherein engagement of the protrusion against the wall resists retraction of the second valve assembly from the first valve assembly. 
     Clause 21. The method of Clause 20, further comprising rotating any of the first valve assembly or the second valve assembly relative to the other of the first valve assembly and the second valve assembly. 
     Clause 22. A valve plug for a fluid connector system, the valve plug comprising: a first end, a second end, and a longitudinal axis that extends between the first and second ends of the valve plug; an inner surface forming a recess that extends through the first end of the valve plug to a floor between the first and second ends of the valve plug; a slit that extends through the second end of the valve plug and the floor; and a first portion of the inner surface forming a ridge that extends into the recess toward the longitudinal axis, and a second portion of the inner surface forming a ramp wall; the ridge comprising a first engagement surface that extends radially inward, in a direction from the first end of the valve plug toward the longitudinal axis, to an apex of the ridge, and a second engagement surface that extends radially outward from the apex and in a direction away from the longitudinal axis, and the ramp wall extending from the second engagement surface to the floor. 
     Clause 23. The valve plug of Clause 33, wherein the ramp wall forms a straight conical surface between the second engagement surface and the floor. 
     Clause 24. The valve plug of Clause 23, wherein the conical surface of the ramp wall extends around the longitudinal axis of the valve plug. 
     Clause 25. The valve plug of Clause 23, wherein the conical surface of the ramp wall extends entirely around the longitudinal axis of the valve plug. 
     Clause 26. The valve plug of any of Clauses 22 to 25, wherein the ridge and the ramp wall form a toroid shape that extends around the longitudinal axis of the valve plug. 
     Clause 27. The valve plug of any of Clauses 22 to 26, wherein a cross-sectional width of the recess, transverse relative to the longitudinal axis, decreases along the first engagement surface from the first end of the valve plug to the apex, and increases along the second engagement surface from the apex to the ramp wall. 
     Clause 28. The valve plug of Clause 27, wherein the cross-sectional width of the recess increases along the ramp wall to the floor of the valve plug. 
     Clause 29. The valve plug of any of Clauses 22 to 28, wherein a cross-sectional width of the recess at the apex is less than a cross-sectional width of the recess along the ramp wall. 
     Clause 30. The valve plug of any of Clauses 22 to 29, wherein the second end of the valve plug comprises a concave surface extending into the valve plug, and the slit extends though the concave surface. 
     Clause 31. The valve plug of any of Clauses 22 to 30, wherein a distance from the first end of the valve plug to the floor of the recess is less than a distance from the floor of the recess to the second end of the valve plug. 
     Clause 32. A fluid connector system comprising: a first valve assembly comprising: a housing having a first end, a second end, wherein the second end is opposite to the first end, and an inner surface forming a cavity that extends through the second end toward the first end of the housing; a post having a proximal end portion and a distal end portion, wherein the distal end portion of the post extends within the cavity in a direction from the first end of the housing toward the second end of the housing; and a fluid passage that extends through the first end of the housing and the post; a second valve assembly comprising: a body having a first end, a second end, wherein the second end is opposite to the first end, an inner surface forming a bore that extends through the second end toward the first end of the body, and a fluid passage that extends through the first end of the body to the bore; a valve plug positioned in the bore, the valve plug having a first end, a second end, and an inner surface forming a recess that extends through the first end of the valve plug to a floor between the first and second ends of the valve plug, a slit that extends through the second end of the valve plug and the floor, and a first portion of the inner surface forming a ridge that extends into the recess toward a longitudinal axis of the valve plug; and wherein, when the first and second valve assemblies are separated from each other, opposing inner surfaces of the valve plug forming the slit are engaged against each other to resist a fluid flow through the valve plug, and when the first and second valve assemblies are coupled together, the distal end portion of the post extends through the slit and the ridge of the valve plug, such that the fluid passage of the first valve assembly is fluidly coupled with the fluid passage of the second valve assembly, and the ridge is engaged against the post to resist movement of a fluid between the post and the ridge. 
     Clause 33. The fluid connector system of Clause 32, wherein a second portion of the inner surface of the valve plug forms a ramp wall having a conical surface extending between the ridge and the floor. 
     Clause 34. The fluid connector system of Clause 33, wherein the conical surface of the ramp wall extends around the longitudinal axis of the valve plug. 
     Clause 35. The fluid connector system of Clause 33, wherein the conical surface of the ramp wall extends entirely around the longitudinal axis of the valve plug. 
     Clause 36. The fluid connector system of Clause 33, wherein a cross-sectional width of the recess, transverse relative to the longitudinal axis, decreases along a first engagement surface of the valve plug that extends from the first end of the valve plug to an apex of the ridge, and increases along a second engagement surface of the valve plug that extends from the apex to the ramp wall. 
     Clause 37. The fluid connector system of Clause 36, wherein the cross-sectional width of the recess increases along the ramp wall to the floor of the valve plug. 
     Clause 38. The fluid connector system of Clause 33, wherein the ridge and the ramp wall form a toroid shape that extends around the longitudinal axis of the valve plug. 
     Clause 39. The fluid connector system of Clause 33, wherein a cross-sectional width of the recess at an apex of the ridge is less than a cross-sectional width of the recess along the ramp wall. 
     Clause 40. The fluid connector system of any of Clauses 32 to 39, wherein the second end of the valve plug comprises a concave surface extending into the valve plug, and the slit extends though the concave surface. 
     Clause 41. The fluid connector system of any of Clauses 32 to 40, wherein, when the first and second valve assemblies are coupled together, a compressible valve of the first valve assembly is engaged against the second end of the valve plug. 
     Further Considerations 
     In some embodiments, any of the clauses herein may depend from any one of the independent clauses or any one of the dependent clauses. In one aspect, any of the clauses (e.g., dependent or independent clauses) may be combined with any other one or more clauses (e.g., dependent or independent clauses). In one aspect, a claim may include some or all of the words (e.g., steps, operations, means or components) recited in a clause, a sentence, a phrase or a paragraph. In one aspect, a claim may include some or all of the words recited in one or more clauses, sentences, phrases or paragraphs. In one aspect, some of the words in each of the clauses, sentences, phrases or paragraphs may be removed. In one aspect, additional words or elements may be added to a clause, a sentence, a phrase or a paragraph. In one aspect, the subject technology may be implemented without utilizing some of the components, elements, functions or operations described herein. In one aspect, the subject technology may be implemented utilizing additional components, elements, functions or operations. 
     The present disclosure is provided to enable any person skilled in the art to practice the various aspects described herein. The disclosure provides various examples of the subject technology, and the subject technology is not limited to these examples. Various modifications to these aspects will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other aspects. 
     A reference to an element in the singular is not intended to mean “one and only one” unless specifically so stated, but rather “one or more.” Unless specifically stated otherwise, the term “some” refers to one or more. Pronouns in the masculine (e.g., his) include the feminine and neuter gender (e.g., her and its) and vice versa. Headings and subheadings, if any, are used for convenience only and do not limit the invention. 
     The word “exemplary” is used herein to mean “serving as an example or illustration.” Any aspect or design described herein as “exemplary” is not necessarily to be construed as preferred or advantageous over other aspects or designs. In one aspect, various alternative configurations and operations described herein may be considered to be at least equivalent. 
     A phrase such as an “aspect” does not imply that such aspect is essential to the subject technology or that such aspect applies to all configurations of the subject technology. A disclosure relating to an aspect may apply to all configurations, or one or more configurations. An aspect may provide one or more examples. A phrase such as an aspect may refer to one or more aspects and vice versa. A phrase such as an “embodiment” does not imply that such embodiment is essential to the subject technology or that such embodiment applies to all configurations of the subject technology. A disclosure relating to an embodiment may apply to all embodiments, or one or more embodiments. An embodiment may provide one or more examples. A phrase such an embodiment may refer to one or more embodiments and vice versa. A phrase such as a “configuration” does not imply that such configuration is essential to the subject technology or that such configuration applies to all configurations of the subject technology. A disclosure relating to a configuration may apply to all configurations, or one or more configurations. A configuration may provide one or more examples. A phrase such a configuration may refer to one or more configurations and vice versa. 
     In one aspect, unless otherwise stated, all measurements, values, ratings, positions, magnitudes, sizes, and other specifications that are set forth in this specification, including in the claims that follow, are approximate, not exact. In one aspect, they are intended to have a reasonable range that is consistent with the functions to which they relate and with what is customary in the art to which they pertain. 
     In one aspect, the term “coupled” or the like may refer to being directly coupled. In another aspect, the term “coupled” or the like may refer to being indirectly coupled. 
     Terms such as “top,” “bottom,” “front,” “rear” and the like if used in this disclosure should be understood as referring to an arbitrary frame of reference, rather than to the ordinary gravitational frame of reference. Thus, a top surface, a bottom surface, a front surface, and a rear surface may extend upwardly, downwardly, diagonally, or horizontally in a gravitational frame of reference. 
     Various items may be arranged differently (e.g., arranged in a different order, or partitioned in a different way) all without departing from the scope of the subject technology. All structural and functional equivalents to the elements of the various aspects described throughout this disclosure that are known or later come to be known to those of ordinary skill in the art are expressly incorporated herein by reference and are intended to be encompassed by the claims. Moreover, nothing disclosed herein is intended to be dedicated to the public regardless of whether such disclosure is explicitly recited in the claims. No claim element is to be construed under the provisions of 35 U.S.C. § 112, sixth paragraph, unless the element is expressly recited using the phrase “means for” or, in the case of a method claim, the element is recited using the phrase “step for.” Furthermore, to the extent that the term “include,” “have,” or the like is used, such term is intended to be inclusive in a manner similar to the term “comprise” as “comprise” is interpreted when employed as a transitional word in a claim. 
     The Title, Background, Summary, Brief Description of the Drawings and Abstract of the disclosure are hereby incorporated into the disclosure and are provided as illustrative examples of the disclosure, not as restrictive descriptions. It is submitted with the understanding that they will not be used to limit the scope or meaning of the claims. In addition, in the Detailed Description, it can be seen that the description provides illustrative examples and the various features are grouped together in various embodiments for the purpose of streamlining the disclosure. This method of disclosure is not to be interpreted as reflecting an intention that the claimed subject matter requires more features than are expressly recited in each claim. Rather, as the following claims reflect, inventive subject matter lies in less than all features of a single disclosed configuration or operation. The following claims are hereby incorporated into the Detailed Description, with each claim standing on its own as a separately claimed subject matter. 
     The claims are not intended to be limited to the aspects described herein, but is to be accorded the full scope consistent with the language claims and to encompass all legal equivalents. Notwithstanding, none of the claims are intended to embrace subject matter that fails to satisfy the requirement of 35 U.S.C. § 101, 102, or 103, nor should they be interpreted in such a way.