Patent Publication Number: US-10780022-B2

Title: Medication packaging and dose regimen system

Description:
CROSS-REFERENCE TO RELATED APPLICATION 
     This application claims the benefits of U.S. Provisional Patent Application No. 62/039,144 filed Aug. 19, 2014, U.S. Provisional Patent Application No. 62/039,152 filed Aug. 19, 2014 and U.S. Provisional Patent Application No. 62/039,201 filed Aug. 19, 2014, the contents of each of these applications being hereby incorporated in their respective entireties by reference. 
    
    
     TECHNICAL FIELD 
     The present disclosure generally relates to medicament packaging and more particularly to a dispensing device and system that provides a medication regimen and/or tamper resistance and a method for treatment of a medical condition. 
     BACKGROUND 
     Retail customers and/or patients can be engaged in a medical therapy, which may include diet, exercise and/or a prescription and/or a non-prescription medication dosing regimen, which may be employed to treat an illness. In some cases, hospitalized patients are often discharged and instructed by one or more medical practitioners to comply with a medical therapy. 
     Such medication dosing regimen can include one or a plurality of medications administered over a regimen, which may include one or more medications. The medication dosing regimen can require administration of medications simultaneously, at different times and/or according to days of a week or time of day. Such medication regimens may be administered in addition to existing medication regimens that a user may take for nutritional, therapeutic and/or illness treatment. 
     Such medication regimens, however, often suffer from poor patient compliance. In fact, many patients fail to comply with their medication regimens. In some cases, life-style related medications may also suffer from poor user compliance. Factors that contribute to non-compliance may include complexity of medication regimen, patient failure in filling prescriptions, incorrect order and/or prescription, cost, adverse side effects, patient reluctance, lack of motivation, non-reconciliation with existing medication and/or patient physiological issues. 
     Various medications of a medication regimen can be dispensed from a medication container such as single dose and/or multiple dose blister packaging to a user with or without tamper resistance. Multiple dose blister packaging can dispense a single medication according to a regimen including day, e.g., Monday, Tuesday, etc. and/or time of day. This disclosure describes an improvement over these prior art technologies. 
     SUMMARY 
     In one embodiment, a medicament dispensing container comprises a first wall and a second wall defining a cavity therebetween. At least one member is connected to at least one of the walls and is disposable in the cavity. The at least one member defines at least one dose receptacle configured for disposal of at least one dose of at least one medication. The at least one member includes indicia relating to a medication regimen comprising the at least one medication. The walls are movable between a medication accessible configuration and a tamper resistant configuration. Systems and methods of use are disclosed. 
    
    
     
       BRIEF DESCRIPTION OF THE DRAWINGS 
       The present disclosure will become more readily apparent from the specific description accompanied by the following drawings, in which: 
         FIG. 1  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 2  is a perspective view of the components shown in  FIG. 1 ; 
         FIG. 3  is a perspective view of the components shown in  FIG. 1 ; 
         FIG. 4  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 5  is a perspective view of components of the system shown in  FIG. 4 ; 
         FIG. 6  is a plan view of a component of the system shown in  FIG. 4 ; 
         FIG. 7  is a plan view of a component of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 8  is a plan view of a component of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 9  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 10  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 11  is a perspective view of the components shown in  FIG. 10 ; 
         FIG. 12  is a perspective view of the components shown in  FIG. 10 ; 
         FIG. 13  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 14  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 15  is a perspective view of a component of the system shown in  FIG. 14 ; 
         FIG. 16  is a perspective view of components of the system shown in  FIG. 14 ; 
         FIG. 17  is a perspective view of components of the system shown in  FIG. 14 ; 
         FIG. 18  is a perspective view of components of the system shown in  FIG. 14 ; 
         FIG. 19  is a perspective view of components of the system shown in  FIG. 14 ; 
         FIG. 20  is a perspective view of components of the system shown in  FIG. 14 ; 
         FIG. 21  is a perspective view of components of the system shown in  FIG. 14 ; 
         FIG. 22  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 23  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 24  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 25  is a perspective view of components of the system shown in  FIG. 23 ; 
         FIG. 26  is a perspective view of components of the system shown in  FIG. 23 ; 
         FIG. 27  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 28  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 29  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 30  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 31  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 32  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 33  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 34  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 35  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 36  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 37  is a perspective view of components of the system shown in  FIG. 36 ; 
         FIG. 38  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 39  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 40  is a side view of the components shown in  FIG. 39 ; 
         FIG. 41  is a side view of the components shown in  FIG. 39 ; 
         FIG. 42  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 43  is a side view of components of the system shown in  FIG. 42 ; 
         FIG. 44  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 45  is a side view of components of the system shown in  FIG. 44 ; 
         FIG. 46  is a side view of components of the system shown in  FIG. 44 ; 
         FIG. 47  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 48  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 49  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 50  is a perspective view of components of one embodiment of a system in accordance with the principles of the present disclosure; 
         FIG. 51  is a perspective view of components of the system shown in  FIG. 50 ; and 
         FIG. 52  is a perspective view of components of the system shown in  FIG. 50 . 
     
    
    
     DETAILED DESCRIPTION 
     The exemplary embodiments of a medicament dispensing system and related methods of use disclosed are discussed in terms of dispensing devices for the treatment of various diseases, illness and/or ailments and more particularly, in terms of a medicament dispensing device and system that provides a medication regimen and/or tamper resistance and a method for treatment of a medical condition. In some embodiments, the medicament dispensing system is employed with a method for distribution of medication packaging to a patient for treatment of one or more diseases, illness and/or ailments. In some embodiments, the medicament dispensing system is employed with a method such that a patient is discharged from a health care facility, for example, short term discharge and/or long term discharge. 
     In one embodiment, the medicament dispensing system is employed with a method such that a patient is discharged from a health care facility, such as, for example, a hospital after one or more diseases, illness and/or ailments, such as, for example, myocardial infarction and may be prescribed one or more medications. In some embodiments, a patient may be directed and/or prescribed medication, such as, for example, an antiplatelet agent, aspirin, a beta-blocker, an ACE inhibitor, an ARB statin, nitro-glycerin, a docusate and/or anti-depressants. In some embodiments, the medicament dispensing system is employed to avoid failure of a patient to comply with such regimens and/or to take medications as prescribed or directed. In some embodiments, compliance failure can include the patient failing to refill the prescription, forgetting to take the prescribed medication, incomplete dosage and/or taking the medication at the incorrect time. In some embodiments, the medicament dispensing system is employed with a method for chronic dosing, for example, 30 day scripts or 90-100 day mail order refills. In some embodiments, the medicament dispensing system is employed with a method to facilitate compliance. In some embodiments, the medicament dispensing system is employed with a method to display and/or prove compliance. For example, a patient attending a practitioner appointment provides a present system, such as, for example, a compliance pack and displays and/or shows the practitioner use of the compliance pack, which may include rupture of one or more blister packs to evidence compliance, as described herein. In some embodiments, the medicament dispensing system is employed with a method for distribution of medication packaging to a patient for treatment of one or more diseases, illness and/or ailments, such as, for example, pneumonia, heart failure, pain, infectious diseases that may include administration of medications, such as, for example, anti-retrovirals (ARV) for treatment of HIV/AIDS, dyslipidemia (high cholesterol), hypertension (high blood pressure), metabolic syndrome/insulin intolerance related to diabetes, psychological diseases and/or administration of transplant/anti-rejection drugs. 
     In some embodiments, the medicament dispensing system comprises a medicament dispensing system and methods of use for storage, transportation and discharge of medications for the treatment of a medical condition. In some embodiments, the medicament dispensing system comprises a medicament dispensing system and methods of use for storage, transportation and discharge of medications including those for treating illnesses, such as, for example, elevated blood pressure, dyslipidemia (high cholesterol), diabetes, metabolic syndrome, heart failure, pneumonia, cardiac deficiencies, arthritis, illnesses in which pain is part of an on-going treatment plan, and/or life-style related medications such as, for example, birth control pills, hormone replacement pills and nutritional supplements, such as, for example, neutraceuticals, for example, having vitamin A, D, and E with a calcium supplement. In some embodiments, the method includes treatment of a heart condition following a myocardial infarction. In one embodiment, the medicament dispensing system and methods of the present disclosure are employed to aid a person with a medical condition requiring administration of multiple pills, doses or schedules as part of a regimen. In one embodiment, the medicament dispensing system and methods of the present disclosure include a medicament dispensing device that provides tamper resistance, such as, for example, child resistance, while being easily accessed by an adult. 
     In one embodiment, a medication container may include multiple medications on a blister card. In one embodiment, the medicament dispensing system provides a complex dosage regimen for medications for a period of time, such as, for example, two weeks. In some embodiments, one or more blister cards are provided pre-filled with medication, as described herein, from a manufacturer. In some embodiments, a practitioner, such as, for example, a pharmacist determines and selects one or more of the pre-filled blister cards based on a doctor&#39;s prescription and creates the medication container. In some embodiments, the manufacturer provides a medication container packed with selected blister cards and pre-filled medication according to the doctor&#39;s prescription. In some embodiments, the complex dosage regimen for the medications is provided for a period lasting until a patient&#39;s first outpatient visit following release from a hospital. In one embodiment, one or more medications are included in a medicament dispensing system. In one embodiment, medications prescribed to a patient following a medical procedure are included in a medicament dispensing system. In one embodiment, medications previously being taken by a patient are included in a medicament dispensing system. 
     In one embodiment, the medication container includes two small organizers, such as, for example, a week one and a week two. In one embodiment, each organizer contains a tri-fold drug card including one week of therapy. In one embodiment, the organizers include a child resistant lock, such as, for example, two white plastic pieces on the outside of the organizer configured in a push and slide configuration. 
     In one embodiment, the medication container includes a simple child resistant non-collapsible box filled with punch cards. In one embodiment, the medication container includes pharmacist insert strips of blisters and seal cards. In one embodiment, the medication container organizes medicines by week and/or by day. In one embodiment, the medication container includes a simpler user interface. In one embodiment, the medication container includes a system to easily track medicine dosage compliance. In one embodiment, the medication container is manufactured with minimal material to reduce cost. In one embodiment, the medication container is configured to include various educational material and/or blister cards. 
     In one embodiment, the medicament dispensing system provides a complex dosage regimen for medications for a period of time, such as, for example, two weeks. In some embodiments, the complex dosage regimen for the medications is provided for a period lasting until a patient&#39;s first outpatient visit following release from a hospital. In one embodiment, one or more medications are included in a medicament dispensing system. In one embodiment, medications prescribed to a patient following a medical procedure are included in a medicament dispensing system. In one embodiment, medications previously being taken by a patient are included in a medicament dispensing system. 
     In some embodiments, the medicament dispensing system comprises medication packaging that includes one or more medications. In some embodiments, the medication packaging includes a member, such as, for example, a unit dose page including indicia. In some embodiments, the indicia includes information regarding medication and dosages required by a prescribed and/or non-prescribed regimen. In some embodiments, the indicia includes a description of medication, which may include a name of a drug and a medical effect of a drug. In one embodiment, the unit dose page may include indicia that represent other medications or dosages to accommodate patients as needed. In one embodiment, the unit dose page may include space for adding indicia that represent other medications or dosages to accommodate patients as needed. In one embodiment, the indicia are screen printed on the unit dose page. In one embodiment, the indicia are hand written on the unit dose page. 
     In some embodiments, the medicament dispensing system is partially or entirely filled and packaged by a pharmacist. In some embodiments, the medicament dispensing system comprises a resilient material, such as, for example, cardboard. In some embodiments, the medicament dispensing system provides a child-resistant package while being easily accessible by an adult. In some embodiments, a method for accessing medication within the medicament dispensing system is provided. In some embodiments, the method includes the step of requiring consecutive and/or simultaneous motions difficult for children to perform but simple for an adult to perform. In one embodiment, the medication packaging comprises a slidable locking mechanism. In some embodiments, the locking mechanism is movable between a non-locked position and a locked position. In some embodiments, the locking mechanism provides audible indication of movement between a non-locked position and a locked position. 
     In one embodiment, the medicament dispensing system includes a medication treatment regimen comprising a plurality of medications. In one embodiment, the medicament dispensing system provides an organization of each medication in a patient&#39;s treatment regimen. In one embodiment, each distinct medication in the regimen is stored on separate unit dose pages contained in a medicament packaging container. In one embodiment, the medicament dispensing system is employed with a method that includes fourteen days of therapy provided on each unit dose page. In one embodiment, medication packaging includes one or more unit dose pages assembled, filled and sealed by a pharmacist. In one embodiment, the medicament packaging container is child resistant and the unit dose pages are not child resistant. 
     The present disclosure may be understood more readily by reference to the following detailed description of the embodiments taken in connection with the accompanying drawing figures, which form a part of this disclosure. It is to be understood that this application is not limited to the specific devices, methods, conditions or parameters described and/or shown herein, and that the terminology used herein is for the purpose of describing particular embodiments by way of example only and is not intended to be limiting. In some embodiments, as used in the specification and including the appended claims, the singular forms “a,” “an,” and “the” include the plural, and reference to a particular numerical value includes at least that particular value, unless the context clearly dictates otherwise. Ranges may be expressed herein as from “about” or “approximately” one particular value and/or to “about” or “approximately” another particular value. When such a range is expressed, another embodiment includes from the one particular value and/or to the other particular value. Similarly, when values are expressed as approximations, by use of the antecedent “about,” it will be understood that the particular value forms another embodiment. It is also understood that all spatial references, such as, for example, horizontal, vertical, top, upper, lower, bottom, left and right, are for illustrative purposes only and can be varied within the scope of the disclosure. For example, the references “upper” and “lower” are relative and used only in the context to the other, and are not necessarily “superior” and “inferior”. 
     As used in the specification and including the appended claims, “treating” or “treatment” of a disease or condition may include administering one or more medications to a patient (human or other mammal). Alleviation can occur prior to signs or symptoms of the disease or condition appearing, as well as after their appearance. Thus, treating or treatment includes preventing or prevention of disease or undesirable condition (e.g., preventing the disease from occurring in a patient, who may be predisposed to the disease but has not yet been diagnosed as having it). In addition, treating or treatment does not require complete alleviation of signs or symptoms, does not require a cure, and specifically includes procedures that have only a marginal effect on the patient. Treatment can include inhibiting the disease, e.g., arresting its development, or relieving the disease, e.g., causing regression of the disease. For example, treatment includes, but is not limited to, reducing acute or chronic inflammation, inducing an anti-platelet effect, reducing hypertension, and lowering cholesterol. 
     In some embodiments, a biologically-active substance includes any substance or substances comprising a medicament, medication or drug including an active therapeutic substance, metabolite, hormone, steroid, vitamin, fatty acid, amino acid, sugar, carbohydrate, polypeptide or mineral. In some embodiments, a biologically-active substance includes any substance used for treatment, prevention, diagnosis, cure or mitigation of disease or illness. In some embodiments, a biologically-active substance includes any substance that affects anatomical structure or physiological function. In some embodiments, a biologically-active substance includes any substance that alters the impact of external influences on an animal, or metabolite thereof. In some embodiments, a complex dosing regimen includes a systematic administration of multiple dosage units at designated times during the day. In some embodiments, a dose includes each individual release of substance into body tissue. 
     The following discussion includes a description of a medicament dispensing system including a medicament dispensing container, related components and methods of employing the medicament dispensing system. Alternate embodiments are also disclosed. Reference is made in detail to the exemplary embodiments of the present disclosure, which are illustrated in the accompanying figures. Turning to  FIGS. 1-8 , there are illustrated components of a medicament dispensing system  10 . 
     The components of medicament dispensing system  10 , individually or collectively, can be fabricated from materials suitable for storage and dispensing of medication. In some embodiments, such materials include metals, ceramics, synthetic polymers such as thermoplastics, semi-rigid and rigid materials, elastomers, fabric and/or their composites. Various components of medicament dispensing system  10  may have material composites, including the above materials, to achieve various desired characteristics such as strength, rigidity, elasticity, compliance, and durability. The components of medicament dispensing system  10 , individually or collectively, may also be fabricated from a heterogeneous material such as a combination of two or more of the above-described materials. The components of medicament dispensing system  10  may be monolithically formed, integrally connected or include fastening elements and/or instruments, as described herein. 
     Medicament dispensing system  10  includes a medicament dispensing device, such as, for example, a medicament dispensing container  12 . Medicament dispensing container  12  includes a wall, such as, for example, a pocket  14  and a wall, such as, for example, a cover  24 . Pocket  14  includes a bottom section  16 , a front sidewall  18 , and opposing sidewalls  20 . In one embodiment, bottom section  16  comprises a rectangular shape. Sidewalls  20  are disposed on opposing sides of bottom section  16  such that sidewall  18  extends between sidewalls  20 . 
     Cover  24  includes a top section  26 , a front sidewall  28 , and opposing sidewalls  30 . Sidewalls  30  are disposed on opposing sides of top section  26  such that sidewall  28  extends between sidewalls  30 . In one embodiment, top section  26  comprises a rectangular shape. Pocket  14  is configured to fit inside cover  24 . In some embodiments, sidewall  28  contacts sidewalls  30  to define a cavity when sidewalls  28 ,  30  are brought into contact with sidewalls  18 ,  20 , as discussed herein. 
     In some embodiments, medicament dispensing container  12  includes a connecting portion, such as, for example, a spine  32 . Spine  32  extends between pocket  14  and cover  24  such that cover  24  is pivotable relative to pocket  14 . Cover  24  is attached to spine  32  at an end opposite sidewall  28 , and pocket  14  is attached to spine  32  at an end opposite sidewall  18 . Cover  24  is pivotable relative to pocket  14  between an open or non-locked configuration, such as, for example a medication accessible configuration, as shown in  FIGS. 3 and 4 , and a closed or locked configuration, such as, for example, a tamper resistant configuration, as shown in  FIG. 1 . In some embodiments, as shown in  FIG. 2 , medicament dispensing container  12  is disposable in a closed, locked and non-tamper resistant configuration such that a locking mechanism is aligned with a locking surface, as described herein. 
     In some embodiments, cover  24  is rotatable relative pocket  14  through an angular range of 0 through 360 degrees. In a closed configuration, spine  32 , sidewalls  18 ,  20 ,  28 ,  30 , and sections  16 ,  26  define a substantially enclosed cavity such that cover  24  and pocket  14  prevent access to contents of medicament dispensing container  12 . In some embodiments, in a closed configuration, cover  24  and pocket  14  provide a child-resistant medicament dispensing container. In an open configuration, pocket  14  is rotated relative to cover  24  such that medicament dispensing container  12  rests flatly on a surface to facilitate ease of access to the contents of the cavity of medicament dispensing container  12 . 
     In some embodiments, spine  32  comprises a coupling assembly, such as, for example, binder rings  34  configured for engagement with unit dose pages  60  and/or information inserts  70 , as discussed herein. In one embodiment, binder rings  34  are configured to engage complementary openings  66  of a unit dose page  60  and/or openings  74  of an information inserts  70 , as discussed herein. In some embodiments, binder rings  34  comprise rings having separable halves to facilitate assembly of unit dose pages  60  and information inserts  70 , and their subsequent removal. Binder rings  34  are connected with spine  32  with a pair of rivets  38  positioned at opposite ends of binder rings  34 . In some embodiments, binder rings  34  can be riveted to spine  32  by clips, screws, pins, nails, bolts, snaps or press studs. In one embodiment, when medicament dispensing container  12  is placed in a closed configuration, spine  32  conforms to the shape of binder rings  34 . 
     Medicament dispensing container  12  includes a mechanism configured to connect pocket  14  with cover  24  for disposal of the components of medicament dispensing container  12  in a closed configuration. In one embodiment, sidewall  18  includes a surface defining one or more apertures  40 . As shown in  FIGS. 2 and 3 , sidewall  18  includes two spaced apart apertures  40  having a circular shape. In some embodiments, aperture  40  may be oval, rectangular, polygonal, irregular, tapered, offset, staggered, uniform and non-uniform. 
     Cover  24  includes a mating element, such as, for example, a tab  42  configured to mate with sidewall  18  and/or apertures  40 . Tab  42  extends along sidewall  28  such that tab  42  is aligned with sidewall  28 . In some embodiments, tab  42  is attached to sidewall  28  via a connection point  44  adjacent top section  26 . In some embodiments, tab  42  flexibly extends from connection point  44 , such that tab  42  is resiliently biased to a selected configuration, as described herein. 
     Tab  42  defines a locking surface, such as, for example, a release button  46 . Release button  46  is positioned adjacent a distal end of tab  42  and extends transversely from tab  42 . In one embodiment, release button  46  has a cylindrical shape to mate with aperture  40 . In some embodiments, release button  46  may include alternate shapes, such as, for example, partially cylindrical, oval, rectangular, polygonal, irregular, tapered, offset, staggered, uniform and non-uniform. In some embodiments, release button  46  may extend in alternate orientations, such as, for example, angled, offset and/or staggered. 
     Tab  42  is configured for resilient engagement with an inner surface of sidewall  18 . As medicament dispensing container  12  is moved between an open configuration and a closed configuration, engagement of tab  42  with sidewall  18  causes tab  42  to move, flex, pivot and/or rotate about connection point  44  between a position such that tab  42  is aligned with sidewall  28  and a position such that tab  42  moves, flexes, pivots and/or rotates into aperture  40 . In some embodiments, the resilient bias of tab  42  causes release button  46  to snap into aperture  40 . 
     When moving from a closed configuration to an open configuration, the user engages release buttons  46  to translate release buttons  46  through apertures  40  out of engagement with sidewall  18 . Cover  24  is rotated about pocket  14  to an open configuration of medicament dispensing container  12 . In some embodiments, release buttons  46  comprise a beveled surface (not shown) adjacent a distal end of tab  42  to facilitate closing medicament dispensing container  12  from an open configuration to a closed configuration. As cover  24  is rotated toward a closed configuration, the beveled surface engages sidewall  18  to cause tab  42  to move, flex, pivot and/or rotate about connection point  44 . Cover  24  is rotated toward a closed position until release buttons  46  snap into apertures  40 . 
     In some embodiments, tab  42  is provided with indicia, such as, for example, instructions to aid a user in use of medicament dispensing container  12 . The instructions may be presented in the form of a graphic, such as, for example, a bulls eye, or text, such as, for example, “push here”. In some embodiments, the instructions may be printed onto a surface of release buttons  46 . In some embodiments, the instructions may be printed onto sidewall  18  adjacent a slide  50 , as described herein. 
     Medicament dispensing container  12  includes a locking mechanism, such as, for example, a slide  50 . Slide  50  is disposed with sidewall  18 . Slide  50  translates relative to sidewall  18  via a slot (not shown) positioned between apertures  40 . The slot defines limits for translation of slide  50  along sidewall  18 . Slide  50  comprises a handle  54  having a surface configured to facilitate translation by the user. In some embodiments, handle  54  may have alternate surface configurations, such as, for example, rough, arcuate, undulating, mesh, porous, semi-porous, dimpled and/or textured to facilitate gripping by a patient. Slide  50  comprises at least one window  56 . Slide  50  comprises two spaced apart windows  56  configured to translate for alignment and non-alignment with apertures  40  for disposal of medicament dispensing container  12  between a locked configuration and a non-locked configuration. 
     Slide  50  is translatable between a locking position, as shown in  FIG. 1 , and a non-locked position, as shown in  FIG. 2 . In a locked position, slide  50  is disposed such that windows  56  and apertures  40  are disposed in non-alignment and apertures  40  are covered by slide  50 . Release buttons  46  are not accessible by a user in a locked position. In a non-locked position, slide  50  is oriented such that windows  56  are aligned with apertures  40  to access release buttons  46 . Release buttons  46  are accessible for engagement to release cover  24  from pocket  14  in a non-locked position. 
     In some embodiments, slide  50  audibly clicks to indicate a locked position. In some embodiments, slide  50  is provided with instructions to aid a patient in use of medicament dispensing container  12 . In some embodiments, the instructions may be presented in the form of a graphic, such as, for example, an arrow with a lock, or text, such as, for example, “slide to unlock”. In some embodiments, the instructions may be printed on slide  50 . Alternatively, in some embodiments, the instructions may be printed onto sidewall  18  adjacent slide  50 . 
     Medicament dispensing container  12  includes one or more unit dose pages  60 , as shown in  FIG. 4 , that store and/or contain one or more medications, such as, for example, a dose of at least one medication. The dose of medication(s) is enclosed and sealed in a plurality of receptacles  62 . In some embodiments, medicament dispensing container  12  includes a plurality of unit dose pages  60 . In some embodiments, each unit dose page  60  encloses a different medication such that each medication that is part of a patient&#39;s dosage regimen is organized on separate unit dose pages  60 . In some embodiments, unit dose page  60  comprises receptacles  62  indicating a patient&#39;s daily dosage of medication held within unit dose page  60 . In some embodiments, unit dose page  60  comprises indicia  64 , disposed with and displayed from a predetermined area adjacent one or more receptacles  62 , indicating information regarding the medication enclosed within receptacles  62 . 
     In some embodiments, medicament dispensing container  12  comprises a disposable dispensing device that provides therapeutic and/or nutritional support to an animal by increasing compliance with a dosing regimen, as described herein. In some embodiments, medicament dispensing container  12  and/or one or more unit dose pages  60  include blister packs, which include a plurality of receptacles  62 . In some embodiments, each receptacle  62  accommodates a dosage unit and isolates that dosage unit from other dosage units. In some embodiments, a biologically-active substance within each dosage unit will not come into contact with the biologically-active substance of other dosage units. 
     In some embodiments, medicament dispensing container  12  and/or one or more unit dose pages  60  include a blister pack comprising at least one row of a plurality of receptacles  62  and/or areas including indicia  64 . In some embodiments, each area defines at least one receptacle  62 . In some embodiments, each receptacle  62  is designed to hold only one dosage unit having either only one biologically-active substance or multiple storage-compatible substances. In some embodiments, each receptacle  62  is designed to hold a plurality of dosage units. 
     In some embodiments, each predetermined area including one or more receptacles  62  may have an independently removable or breakable seal. In some embodiments, each receptacle  62  is moisture resistant and independently sealed. In some embodiments, one or more receptacles  62  may comprise a blister pack including a push-through pack, which has a lid material of aluminum foil or aluminum foil laminate. In some embodiments, a base of one or more receptacles  62  may be plastic, such as, for example, PVC, polyamides, polyolefins, polyesters and laminates or multi-layered materials. In some embodiments, the lid foil of a receptacle  62  may be provided with a line of weakness in a region of each receptacle  62  such that the line of weakness may be a tab for gripping that enables a receptacle  62  to be exposed by manipulation of the lid foil. 
     In some embodiments, receptacle  62  may be made embossed, cast deep drawn or vacuum formed out of plastic, plastic laminates, plastic/paper laminates or plastic/metal foil laminates. In some embodiments, receptacle  62  comprises a barrier layer against gases and vapors, which may be fabricated from a metal foil such as an aluminum foil embedded in a plastic laminate or ceramic layers or metallic layers embedded between two plastic layers. 
     In some embodiments, a dose of medicament, medication or drug can include, such as, for example, a chewable tablet, quick dissolve tablet, effervescent tablet, reconstitutable powder, elixir, liquid, solution, suspension, emulsion, tablet, multi-layer tablet, bi-layer tablet, capsule, soft gelatin capsule, hard gelatin capsule, caplet, lozenge, chewable lozenge, bead, powder, granules, dispersible granules, cachets, douche, suppository, cream, topical, inhalant, aerosol inhalant, patch, particle inhalant, implant, depot implant, dragee, ampoule, ingestible, injectable, infusion, health bar, liquid, food, nutritive food, functional food, yogurt, gelatin, cereal, cereal coating, animal feed and/or combinations thereof. 
     In some embodiments, indicia  64  of a medication regimen, direction, instruction and/or prescription for administration of the medication regimen may include dosage day indicia, a specific day of the week, such as Monday, Tuesday, Wednesday, Thursday, Friday, Saturday, Sunday or an abbreviation of said day, a specific date or a general succession of days, such as day 1, day 2, day 3. In some embodiments, indicia  64  may include time indicia that may be, such as, for example, a general time of the day corresponding to each of receptacles  62  or a specific time of the day corresponding to each of receptacles  62 , such as, for example, AM, PM, morning, afternoon, evening, day, night, daytime, nighttime and combinations thereof. In some embodiments, indicia  64  may include each separate row or column of a unit dose page  60  indicating a time of day, such as AM doses and PM doses. In some embodiments, receptacle  62  and/or an adjacent area may be color coded for time indicia. In some embodiments, one or more components of medicament dispensing system  10  may include a key defining or explaining color coding. 
     In some embodiments, a dose unit may comprise vitamin A, B vitamins, vitamin C, vitamin D, vitamin E, vitamin K, essential fatty acids, folic acid, iron, calcium, magnesium, potassium, copper, chromium, zinc, molybdenum, iodine, boron, selenium, manganese, derivatives thereof and/or combinations thereof. In some embodiments, biologically-active substances may include thiamin, thiamin pyrophosphate, riboflavin, flavin mononucleotide, flavin adenine dinucleotide, niacin, nicotinic acid, nicotinamide, niacinamide, nicotinamide adenine dinucleotide, tryptophan, biotin, pantothenic acid, ascorbic acid, retinol, retinal, retinoic acid, beta-carotene, 1,25-dihydroxycholecalciferol, 7-dehyrdocholesterol, alpha-tocopherol, tocopherol, tocotrienol, menadione, menaquinone, phylloquinone, naphthoquinone, calcium, calcium carbonate, calcium sulfate, calcium oxide, calcium hydroxide, calcium apatite, calcium citrate-malate, calcium gluconate, calcium lactate, calcium phosphate, calcium levulinate, phosphorus, potassium, sulfur, sodium, docusate sodium, chloride, magnesium, magnesium stearate, magnesium carbonate, magnesium oxide, magnesium hydroxide, magnesium sulfate, copper, iodine, zinc, chromium, molybdenum, carbonyl iron, ferrous fumarate, polysaccharide iron, and/or combinations and derivatives thereof. 
     In some embodiments, a dose unit may be prescription and/or non-prescription substances. In some embodiments, the prescription substance may be a hormone replacement agent, a contraceptive agent, an osteoporotic agent, a chemotherapeutic agent, an anti-infective agent, analgesic, a steroid, an appetite suppressant, a weight loss agent, a tobacco antagonist, a cholesterol reducer and/or combinations thereof. 
     In some embodiments, the prescription substances may include, such as, for example, ticagrelor (anti-platelet), clopidogrel (anti-platelet), prasugrel (anti-platelet), carvedilol (beta blocker), metoprolol succinate (beta blocker), metoprolol tartrate (beta blocker), lisinopril (ACE inhibitor), losartan (angiotensin receptor blocker), valsartan (angiotensin receptor blocker), atorvastatin (statin), simvastatin (statin), spironolactone (aldosterone receptor blocker/diuretic), atenolol, erythromycin, penicillins, cephalosporins, theophylline, albuterol, terbutaline, diltiazem, propranolol, nifedepine, clonidine, thioridazine, diazepam, meclizine, ergoloid mesylates, chlorpromazine, carbidopa, levodopa, beclomethasone diproprionate, budesonide, dexamehasone, flunisolide, fluticasone proprionate, mometasone furoate, triamcinolone acetonide, beconase, pulmicort, rhinocort, decadron, aerobid/nasolide, flovent/flonase, azmacort, amprenavir, adefovir dipivoxil, zidovudine, azidothymidine, AZT, paclitaxel, cyclophosphamide, teniposide, taxol, cytoxan, vumon, methotrexate, methotrexate, cisplatin, carboplatin, oxaliplatin, platinol, paraplatin, adriamycin, bleomycin, dactinomycin, daunorubicin, doxorubicin, indarubicin, mitomycin, blenoxane, cosmegen, cerubidine, rubex, indamycin, mutamycin, BCNU, streptozocin, vinblastine, thiotepa, conjugated estrogens, esterified estrogens, estropipate, estradiol, ethinyl estradiol, medroxyprogesterone, meprobamate, desogestrel, levonorgestrel, norethindrone, norethindrone acetate, norgestimate, norgestrel, raloxifene, tamoxifen, methyltestosterone, quinapril, sotalol, alendronate, atorvastatin, colestipol, clofibrate, and/or combinations thereof. 
     In some embodiments, the non-prescription substance can be a vitamin or derivative thereof, and/or a mineral compound or derivative thereof. In some embodiments, the vitamin or mineral compound may be, such as, for example, thiamin, thiamin pyrophosphate, riboflavin, flavin mononucleoride, flavin adenine dinucleotide, niacin, nicotinic acid, nicotinamide, niacinamide, nicotinamide adenine dinucleotide, tryptophan, biotin, folic acid, pantothenic acid, ascorbic acid, retinol, retinal, retinoic acid, beta-carotene, 1,25-dihydroxycholecalciferol, 7-dehydrocholesterol, alpha-tocopherol, tocopherol, tocotrienol, menadione, menaquinone, phylloquinone, naphthoquinone, calcium, calcium carbonate, calcium sulfate, calcium oxide, calcium hydroxide, calcium apatite, calcium citrate-malate, calcium gluconate, calcium lactate, calcium phosphate, calcium levulinate, phosphorus, potassium, sulfur, sodium, docusate sodium, chloride, magnesium, magnesium stearate, magnesium carbonate, magnesium oxide, magnesium hydroxide, magnesium sulfate, copper, iodine, zinc, chromium, molybdenum, carbonyl iron, ferrous fumarate, polysaccharide iron, and combinations and derivatives thereof. In some embodiments, the derivatives of vitamin compounds include salts, alkaline salts, esters and chelates of any vitamin compound. In some embodiments, the nonprescription substance can be a herbal compound, herbal extract, derivative thereof and/or combinations thereof. 
     In some embodiments, a medication regimen can include a first dosage unit arrayed on a blister pack of receptacles  62  adjacent to a second dosage unit. In some embodiments, the medication regimen includes a first dosage unit disposed adjacent to a second dosage unit disposed with different receptacles  62 . 
     In some embodiments, as shown in  FIG. 6 , unit dose page  60  comprises fourteen receptacles  62 . One dosage unit is enclosed in each receptacle  62 . Receptacles  62  are horizontally arranged in two rows adjacent to one another. In one embodiment, the rows are organized into weeks such that each row comprises seven receptacles  62 . Unit dose page  60  comprises indicia  64  indicating the time and order in which the medications are to be taken by the patient. Each receptacle  62  is labeled with an arrow having the day the dosage should be taken according to a dosage regimen. Indicia  64  are screen printed on unit dose page  60 . In some embodiments, indicia  64  may be hand written. Sections of unit dose page  60  are left blank to allow hand written notes or instructions by a patient, pharmacist or doctor. Unit dose page  60  comprises openings  66  to engage binder rings  34 . 
     In one embodiment, as shown in  FIG. 7 , unit dose page  60  comprises twenty-eight receptacles  62 . One dosage unit is enclosed in each receptacle  62 . Receptacles  62  are vertically arranged in two groupings of two rows adjacent to one another. The groupings are organized into weeks such that each grouping comprises fourteen receptacles  62 . Unit dose page  60  comprises indicia  64  indicating the time and order in which the medications are to be taken by the patient. Each receptacle  62  is labeled with a number to indicate the day of a dosage regimen the medications should be taken. Indicia  64  includes graphics to indicate the time of day the medications should be taken. Indicia  64  are screen printed on page  60 . In some embodiments, indicia  64  may be hand written. Sections of page  60  are left blank to allow hand written notes or instructions by a patient, pharmacist or doctor. Unit dose page  60  comprises openings  66  to engage binder rings  34 . 
     In some embodiments, unit dose page  60  comprises indicia  64  to indicate the name and/or nature of the medications being administered. In some embodiments, indicia  64  include a list of possible side effects of the medications being administered. In some embodiments, indicia  64  provide instructions on how long a patient should take the medication being administered. 
     In some embodiments, as shown in  FIGS. 4 and 5 , medicament dispensing system  10  comprises one or more information inserts  70  to educate a patient about a medication being administered in the dosage regimen. In some embodiments, information insert  70  comprises indicia  72  to indicate the name and/or nature of the medicine being administered. In some embodiments, indicia  72  include a list of possible side effects of the medications being administered. In some embodiments, indicia  72  provide instructions on how long a patient should take the medication being administered. Information insert  70  comprises openings to engage binder rings  34 . In some embodiments, medicament dispensing system  10  includes a notepad  76  configured to fit into the cavity created when container  12  is in the closed configuration to facilitate a doctor, pharmacist, health care personnel and/or patient creating personalized reminders and notes for a patient. 
     In some embodiments, information insert  70  is printed onto a separate page to be viewed in tandem with unit dose page  60 . In some embodiments, information insert  70  is printed onto the back of a first unit dose page  60  such that when a first unit dose page  60  is flipped, the information on information insert  70  corresponds with a second unit dose page  60  positioned behind the first unit dose page  60 . In another embodiment, information insert  70  is printed onto a sticker label and is adhered to the back of first unit dose page  60  such that when a first unit dose page  60  is flipped, the information on information insert  70  corresponds with a second unit dose page  60  positioned behind the first unit dose page  60 . 
     In one embodiment, medicament dispensing system  10 , similar to the systems and methods described herein, including medicament dispensing container  12 , as described herein, is employed in connection with treatment of a disease, illness and/or ailment of a patient. The components of medicament dispensing system  10  facilitate user/patient compliance with a medication regimen, as described herein, upon discharge from a health care facility, such as, for example, a hospital. In one embodiment, a patient utilizes medicament dispensing system  10  after being discharged from a hospital following a myocardial infarction and may be prescribed and/or directed to administer one or a plurality of prescription and/or non-prescription medications. For example, a patient may be prescribed an antiplatelet agent, aspirin, warfarin (anti-coagulant), a beta-blocker, an ACE inhibitor, a statin, nitro-glycerin, a docusate, and/or antidepressants in connection with treatment for the myocardial infarction. 
     In some embodiments, a medical practitioner and/or pharmacist reviews and/or considers medications including one or more prescriptions in connection with treatment for the myocardial infarction, one or more non-prescribed medications directed for administration by the patient in connection with treatment for the myocardial infarction, one or more existing prescriptions and/or one or more non-prescription medications and supplements being taken by the patient. The medical practitioner and/or pharmacist determines a medication regimen based on these medications using medicament dispensing system  10  to facilitate user/patient compliance with the medication regimen. 
     In some embodiments, based on the determined mediation regimen, health care personnel, such as, for example, pharmacy personnel prepare selected unit dose pages  60 , information inserts  70  and/or notepads  76 , as described herein, for disposal with a selected medicament dispensing container  12  specifically created for the myocardial infarction and the user/patient upon discharge from the hospital. 
     Medicament dispensing container  12  is portable such that the user/patient transports and/or carries medicament dispensing container  12  upon discharge. Slide  50  is translated from a child-tamper resistant position, as shown in  FIG. 1 , to a non-locked position, as shown in  FIG. 2 . Release buttons  46  are simultaneously engaged to release tabs  42  from engagement with wall  18 , as shown in  FIG. 3 , to release cover  24  from pocket  14 . The contents of pocket  14 , which may include unit dose pages  60 , information inserts  70  and/or notepads  76 , as described herein, are accessible to the user/patient, as shown in  FIG. 4 . The user/patient employs the components of medicament dispensing system  10 , for example, following direction via indicia  64  for administering dosage units from receptacles  62  and/or following instruction from indicia  64 , information inserts  70  and/or notepads  76 , to facilitate user/patient compliance with the medication regimen in connection with treatment for the myocardial infarction. Slide  50  can be translated to a locked position such that medicament dispensing container  12  is disposable in a child-tamper resistant, locked configuration, as shown in  FIG. 1 , for storage and subsequent use. 
     In one embodiment, as shown in  FIG. 9 , medicament dispensing system  10 , similar to the systems and methods of use of medicament dispensing system  10  described herein, includes a medicament dispensing device, such as, for example, a medicament dispensing container  112 . Medicament dispensing container  112  includes a wall, such as, for example, a pocket  114  and a wall, such as, for example, a cover  124 . Pocket  114  includes a bottom section  116  and a sidewall  118  extending around the perimeter of section  116 . In one embodiment, bottom section  116  comprises a rectangular shape. 
     Cover  124  includes a top section  126 , and a sidewall  128  extending around the perimeter of section  126 . In one embodiment, section  126  comprises a rectangular shape. Pocket  114  is configured to fit inside cover  124 . In some embodiments, sidewalls  118 ,  128  define a cavity when sidewall  128  is brought into contact with sidewall  118  as discussed herein. Container  112  includes a folder flap  130  positioned opposite cover  124 . Flap  130  includes a sleeve  131  configured to receive an information insert  170 , as disclosed herein. In some embodiments, flap  130  is attached to medicament dispensing container  112  at a connecting portion, such as, for example, a spine  132 . Spine  132  is disposed with pocket  114  such that flap  130  is pivotable relative to pocket  114 . Flap  130  is attached to spine  132  at an end opposite cover  124 . 
     Cover  124  and flap  130  are each pivotable relative to pocket  114  between an open or non-locked configuration, such as, for example a medication accessible configuration, and a closed or locked configuration, such as, for example, a tamper resistant configuration, similar to that described herein. In some embodiments, medicament dispensing container  112  is disposable in a closed, locked and non-tamper resistant configuration such that a slide  150  is aligned with release buttons  146 , as described herein. 
     In some embodiments, cover  124  is rotatable relative pocket  114  through an angular range of 0 through 360 degrees. In some embodiments, flap  130  is oppositely positioned from cover  124  and is rotatable relative to pocket  114  through an angular range of 0 through 360 degrees. In a closed configuration, spine  132 , sidewalls  118 ,  128 , and sections  116 ,  126  define a substantially enclosed cavity such that cover  124  and pocket  114  prevent access to contents of medicament dispensing container  112 . In some embodiments, in a closed configuration, cover  124  and pocket  114  provide a child-resistant medicament dispensing container. In an open configuration, cover  124  and flap  130  are rotated relative to pocket  114  such that medicament dispensing container  112  rests on a surface to facilitate ease with the enclosed cavity is exposed to access to the contents of container  112 . 
     In some embodiments, sidewall  118  comprises a coupling assembly, such as, for example, binder rings  134  disposed with an inner surface. Binder rings  134  are configured for engagement with unit dose pages  160  and/or information inserts  170 , as discussed herein, similar to medicament dispensing system  10 . In some embodiments, binder rings  134  comprise rings having separable halves to facilitate assembly of unit dose pages  160  and information inserts  170 , and their subsequent removal. Binder rings  134  are connected with sidewall  118  with a pair of rivets positioned at opposite ends of binder rings  134 . In some embodiments, binder rings  134  can be riveted to sidewall  118  by clips, screws, pins, nails, bolts, snaps or press studs. 
     Medicament dispensing container  112  includes a mechanism configured to connect pocket  114  with cover  124  for disposal of the components of medicament dispensing container  112  in a closed configuration. In one embodiment, sidewall  118  includes a surface defining one or more apertures  140 . Sidewall  118  includes two oppositely positioned apertures  140  having a circular shape. 
     Cover  124  includes a mating element, such as, for example, a release button  146  configured to mate with apertures  140 . Button  146  is positioned adjacent a distal end of sidewall  128  and extends transversely from an outer surface of sidewall  128 . In one embodiment, release button  146  has a cylindrical shape to mate with aperture  140 . 
     Sidewall  128  is configured for resilient engagement with an inner surface of sidewall  118 . As medicament dispensing container  112  is moved between an open configuration and a closed configuration, engagement of sidewall  128  with sidewall  118  causes sidewall  128  to move, flex, pivot and/or rotate relative to section  126 . In some embodiments, a resilient bias of sidewall  128  causes button  146  to snap into aperture  140 . 
     When moving from a closed configuration to an open configuration, the user engages release buttons  146  to translate release buttons  146  through apertures  140  out of engagement with sidewall  118 . Cover  124  is rotated about pocket  114  to an open configuration of medicament dispensing container  112 . In some embodiments, release buttons  146  comprise a beveled surface (not shown) adjacent a distal end of sidewall  128  to facilitate closing medicament dispensing container  112  from an open configuration to a closed configuration. As cover  124  is rotated toward a closed configuration, the beveled surface engages sidewall  118  to cause sidewall  128  to move, flex, pivot and/or rotate. Cover  124  is rotated toward a closed position until release buttons  146  snap into apertures  140 . 
     In some embodiments, sidewall  128  is provided with indicia, such as, for example, instructions to aid a user patient in use of medicament dispensing container  112 . The instructions may be presented in the form of a graphic, such as, for example, a bulls eye, or text, such as, for example, “push here”. In some embodiments, the instructions may be printed onto a surface of release buttons  146 . In some embodiments, the instructions may be printed onto sidewall  118  adjacent slide  150 , as described herein. 
     Medicament dispensing container  112  includes a locking mechanism, such as, for example, a slide  150 . Slide  150  is disposed with sidewall  118 . Slide  150  translates relative to sidewall  118  via a slot (not shown) positioned adjacent aperture  140 . The slot defines limits for translation of slide  150  along sidewall  118 . Slide  150  comprises a handle  154  having a surface configured to facilitate translation by the user. Slide  150  comprises at least one window  156 . Slide  150  comprises two spaced apart windows  156  configured to translate for alignment and non-alignment with apertures  140  for disposal of medicament dispensing container  112  between a locked configuration and a non-locked configuration. In one embodiment, container  112  comprises two oppositely positioned slides  150  for alignment with two oppositely positioned apertures  140 . 
     Slide  150  is translatable between a locking position and a non-locked position, similar to that described herein. In a locked position, slide  150  is disposed such that windows  156  and apertures  140  are disposed in non-alignment and apertures  140  are covered by slide  150 . Release buttons  146  are not accessible by a user in a locked position. In a non-locked position, slide  150  is oriented such that windows  156  are aligned with apertures  140  to access release buttons  146 . Release buttons  146  are accessible for engagement to release cover  124  from pocket  114  in a non-locked position. 
     In some embodiments, slide  150  audibly clicks to indicate a locked position. In some embodiments, slide  150  is provided with instructions to aid a patient in use of medicament dispensing container  112 . In some embodiments, the instructions may be presented in the form of a graphic, such as, for example, an arrow with a lock, or text, such as, for example, “slide to unlock”. In some embodiments, the instructions may be printed on slide  150 . Alternatively, in some embodiments, the instructions may be printed onto sidewall  118  adjacent slide  150 . 
     Medicament dispensing container  112  comprises one or more unit dose pages  160 , similar to unit dose pages  60  described herein, which store and/or contain one or more medications, such as, for example, a dose of at least one medication. In some embodiments, medicament dispensing system  110  comprises one or more information inserts  170 , similar to information inserts  70  described herein, to educate a patient about a medication being administered in the dosage regimen. 
     In use, similar to that described herein, medicament dispensing container  112  is portable such that the user/patient transports and/or carries medicament dispensing container  112  upon discharge. Slide  150  is translated from a child-tamper resistant position to a non-locked position. Release buttons  146  are simultaneously engaged to release tabs  142  from engagement with wall  118  to release cover  124  from pocket  114 . The contents of pocket  114 , which may include unit dose pages  160 , information inserts  170 , as described herein, are accessible to the user/patient. The user/patient employs the components of medicament dispensing system  10 , for example, following direction via indicia on pages unit dose  160  for administering dosage units from receptacles and/or following instruction from indicia on information inserts  170  to facilitate user/patient compliance with the medication regimen in connection with a treatment, as described herein. Slide  150  can be translated to a locked position such that medicament dispensing container  112  is disposable in a child-tamper resistant, locked configuration for storage and subsequent use. 
     In one embodiment, as shown in  FIGS. 10-12 , medicament dispensing system  10 , similar to the systems and methods of use described herein, includes a medicament dispensing device, such as, for example, a medicament dispensing container  212 . Medicament dispensing container  212  includes a wall, such as, for example, a pocket  214  and a wall, such as, for example, cover  224 . Pocket  214  includes a bottom section  216 , a front sidewall  218 , and opposing sidewalls  220 . In one embodiment, bottom section  216  comprises a rectangular shape. Sidewalls  220  are disposed on opposing sides of bottom section  216  such that sidewall  218  extends between sidewalls  220 . Cover  224  includes a top section  226 . In some embodiments, section  226  contacts sidewalls  218 ,  220  to define a cavity, as discussed herein. 
     In some embodiments, medicament dispensing container  212  includes a connecting portion, such as, for example, a spine  232 . Spine  232  extends between pocket  214  and cover  224  such that cover  224  is pivotable relative to pocket  214 . Cover  224  is attached to spine  232  at an end adjacent pocket  214 , and pocket  214  is attached to spine  232  at an end opposite sidewall  218 . Cover  224  is pivotable relative to pocket  214  between an open or non-locked configuration, such as, for example a medication accessible configuration and a closed or locked configuration, such as, for example, a tamper resistant configuration. In some embodiments medicament dispensing container  212  is disposable in a closed, locked and non-tamper resistant configuration such that a knob  250  is aligned with release buttons  246  to prevent buttons  246  from being engaged, as described herein. 
     In some embodiments, cover  224  is rotatable relative pocket  214  through an angular range of 0 through 360 degrees. In a closed configuration, spine  232 , sidewalls  218 ,  220  and sections  216 ,  226  define a substantially enclosed cavity such that cover  224  and pocket  214  prevent access to contents of medicament dispensing container  212 . In some embodiments, in a closed configuration, cover  224  and pocket  214  provide a child-resistant medicament dispensing container. In an open configuration, pocket  214  is rotated relative to cover  224  such that medicament dispensing container  212  rests flatly on a surface to facilitate ease of access to the contents of the cavity of medicament dispensing container  212 . 
     In some embodiments, spine  232  comprises a coupling assembly, such as, for example, binder rings  234  configured for engagement with unit dose pages  260 , similar to unit dose pages  60  and/or  160  described herein, and/or information inserts, similar to information inserts  70  and/or  170 , as described herein. In one embodiment, binder rings  234  are configured to engage complementary openings of a unit dose page  260  and/or openings of an information insert, as discussed herein. In some embodiments, binder rings  234  comprise rings having separable halves to facilitate assembly of unit dose pages  260  and their subsequent removal. Binder rings  234  are connected with spine  232  with a pair of rivets positioned at opposite ends of binder rings  234 . In some embodiments, binder rings  234  can be riveted to spine  232  by clips, screws, pins, nails, bolts, snaps or press studs. In one embodiment, when medicament dispensing container  212  is placed in a closed configuration, spine  232  conforms to the shape of binder rings  234 . 
     Medicament dispensing container  212  includes a mechanism configured to connect pocket  214  with cover  224  for disposal of the components of medicament dispensing container  212  in a closed configuration. In one embodiment, sidewall  218  includes a surface defining one or more apertures  240 . Sidewall  218  includes two oppositely positioned apertures  240  having a circular shape. 
     Cover  224  includes a mating element, such as, for example, a tab  242  configured to mate with sidewall  218  and/or apertures  240 . Tab  242  extends along sidewall  228  such that tab  242  is aligned with sidewall  228 . In some embodiments, tab  242  is attached to sidewall  228  via a connection point  244  adjacent top portion  226 . In some embodiments, tab  242  flexibly extends from connection point  244 , such that tab  242  is resiliently biased to a selected configuration, as described herein. 
     Tab  242  defines a locking surface, such as, for example, a release button  246 . Release button  246  is positioned adjacent a distal end of tab  242  and extends transversely from tab  242 . In one embodiment, release button  246  has a cylindrical shape to mate with aperture  240 . 
     Tab  242  is configured for resilient engagement with an inner surface of sidewall  218 . As medicament dispensing container  212  is moved between an open configuration and a closed configuration, engagement of tab  242  with sidewall  218  causes tab  242  to move, flex, pivot and/or rotate about connection point  244  between a position such that tab  242  is aligned with sidewall  228  and a position such that tab  242  moves, flexes, pivots and/or rotates into aperture  240 . In some embodiments, the resilient bias of tab  242  causes button  246  to snap into aperture  240 . 
     When moving from a closed configuration to an open configuration, the user engages release buttons  246  by inserting a finger or the like adjacent and/or behind knobs  250  to flex knobs  250  out of alignment with buttons  246  such that release buttons  246  translate through apertures  240  out of engagement with sidewall  218 . Cover  224  is rotated about pocket  214  to an open configuration of medicament dispensing container  212 . In some embodiments, release buttons  246  comprise a beveled surface (not shown) adjacent a distal end of tab  242  to facilitate closing medicament dispensing container  212  from an open configuration to a closed configuration. As cover  224  is rotated toward a closed configuration, the beveled surface engages sidewall  218  to cause tab  242  to move, flex, pivot and/or rotate about connection point  244 . Cover  224  is rotated toward a closed position until release buttons  246  snap into apertures  240 . 
     In some embodiments, tab  242  is provided with indicia, such as, for example, instructions to aid a user patient in use of medicament dispensing container  212 . The instructions may be presented in the form of a graphic, such as, for example, a bulls eye, or text, such as, for example, “push here”. In some embodiments, the instructions may be printed onto a surface of knob  250 . In some embodiments, the instructions may be printed onto sidewall  218  adjacent a knob  250 , as described herein. 
     Knob  250  is depressible to move container  212  between a locked position, as shown in  FIG. 10 , and a non-locked position, as shown in  FIGS. 11 and 12 . In a locked position, buttons  246  are disposed in apertures  240 . Knob  250  is pressed to release buttons  246  from apertures  240 . Release buttons  246  are accessible for engagement to release cover  224  from pocket  214  in a non-locked position. 
     Medicament dispensing container  12  comprises one or more unit dose pages  260 , similar to unit dose pages  60  and/or  160  described herein, as shown in  FIG. 12 , that store and/or contain one or more medications, such as, for example, a dose of at least one medication. In some embodiments, medicament dispensing system  210  comprises one or more information inserts, similar to information inserts  70  and/or  170  described herein, to educate a patient about a medication being administered in the dosage regimen. In one embodiment, the insert comprises openings to engage binder rings  234 . 
     In use, similar to that described herein, medicament dispensing container  212  is portable such that the user/patient transports and/or carries medicament dispensing container  212  upon discharge. Knob  250  is pressed to move container  212  from a child-tamper resistant position to a non-locked position. Release buttons  246  are simultaneously engaged to release tabs  242  from engagement with sidewalls  220  to release cover  224  from pocket  214 . The contents of pocket  214 , which may include unit dose pages  260  and information inserts, as described herein, are accessible to the user/patient. The user/patient employs the components of medicament dispensing system  210 , for example, following direction via indicia on unit dose pages  260  for administering dosage units from receptacles and/or following instruction from indicia on the inserts to facilitate user/patient compliance with the medication regimen in connection with a treatment, as described herein. Tabs  242  are brought back into contact with sidewalls  220  to a locked position in which buttons  246  engage apertures  240  such that medicament dispensing container  212  is disposable in a child-tamper resistant, locked configuration for storage and subsequent use. 
     In one embodiment, as shown in  FIG. 13 , medicament dispensing system  10 , similar to the systems and methods of use described herein, includes a receptacle, such as, for example, a stack organizer  312 . Stack organizer  312  includes a stackable configuration to facilitate efficient storage of medicament dispensing containers, such as, for example, medicament dispensing containers  212 . In some embodiments, stack organizer  312  is configured for disposal of containers  212  in a linear and/or axial orientation. In some embodiments, stack organizer  312  is configured for disposal of medicament dispensing containers  212  in a staggered, offset, row or column orientation. 
     Stack organizer  312  is divided into sections  314 . Sections  314  include compartments  316  separated by partitions  318 . Each compartment  316  includes a wall  320  and openings  322 . In some embodiments, stack organizer  312  is divided into five compartments  316 . Each compartment  316  is equally sized and configured. In some embodiments, stack organizer  312  includes one or more compartments. 
     In one embodiment, as shown in  FIGS. 14-21 , medicament dispensing system  10 , similar to the systems and methods of use described herein, includes a medicament dispensing device, such as, for example, a medicament dispensing container  412 , similar to medicament dispensing container  212  described herein, a receptacle, such as, for example, an organizer  480  and a receptacle, such as, for example, a flexible tote bag  490  for disposal of components of system  10 , such as, for example, medicament dispensing container  412 , similar to medicament dispensing containers  12 ,  112  and  212 , and organizer  480 . 
     Medicament dispensing container  412  includes a cover  424  that is pivotable between an open or non-locked configuration, such as, for example a medication accessible configuration, as shown in  FIGS. 19-21 , and a closed or locked configuration, such as, for example, a tamper resistant configuration, as shown in  FIG. 17 . Medicament dispensing container  412  comprises one or more unit dose pages  460 , similar to unit dose pages  260  described herein that store and/or contain one or more medications, such as, for example, a dose of at least one medication. 
     Organizer  480  is divided into sections that include compartments  482  separated by partitions  484 . In some embodiments, each compartment  482  is equally sized and configured. Organizer  480  includes a folder flap  486  attached to organizer  480 . Flap  486  is pivotable relative to organizer  480 . 
     In one embodiment, as shown in  FIGS. 22-31 , medicament dispensing system  10 , similar to the systems and methods of use described herein, includes a medicament dispensing device, such as, for example, a medicament dispensing container  512 . 
     Medicament dispensing container  512  includes a wall, such as, for example, a pocket  514  and a wall, such as, for example, a pocket  524 . Pocket  514  includes a bottom section  516 , a front sidewall  518 , and opposing sidewalls  520 . Walls  518 ,  520  define a surface  522 . In one embodiment, bottom section  516  comprises a rectangular shape. Sidewalls  520  are disposed on opposing sides of bottom section  516  such that sidewall  518  extends between sidewalls  520 . 
     Pocket  524  includes a top section  526 , a front sidewall  528 , and opposing sidewalls  530 . Sidewalls  530  are disposed on opposing sides of top section  526  such that sidewall  528  extends between sidewalls  530 . Walls  528 ,  530  define a surface  532 . In one embodiment, top section  526  comprises a rectangular shape. Surface  522  is configured to mate with surface  532  to close medicament dispensing container  512 . In one embodiment, pocket  524  includes an outer surface  542  that defines an outer pocket  544 . Pocket  544  is configured for slidable disposal of, such as, for example, information inserts  570  and/or notepads  576  and/or other educational material. 
     In some embodiments, medicament dispensing container  512  includes a connecting portion, such as, for example, a spine  540 . Spine  540  extends between pocket  514  and pocket  524  such that pocket  524  is pivotable relative to pocket  514 . Pocket  524  is attached to spine  540  at an end opposite sidewall  528 , and pocket  514  is attached to spine  540  at an end opposite sidewall  518 . Pocket  524  is pivotable relative to pocket  514  between an open or non-locked configuration, such as, for example a medication accessible configuration, as shown in  FIG. 22 , and a closed or locked configuration, such as, for example, a tamper resistant configuration. In some embodiments, as shown in  FIG. 27 , medicament dispensing container  512  is disposable in a closed, locked and non-tamper resistant configuration with a locking mechanism  550 . 
     In some embodiments, pocket  524  is rotatable relative to pocket  514  through an angular range of 0 through 360 degrees. In a closed configuration, as shown in  FIG. 27 , spine  540 , sidewalls  518 ,  520 ,  528 ,  530 , and sections  516 ,  526  define a substantially enclosed cavity  554  configured for disposal of unit dose pages  560  and/or information inserts  570 , as discussed herein, such that pocket  524  and pocket  514  prevent access to contents of medicament dispensing container  512 . In some embodiments, in a closed configuration, pocket  524  and pocket  514  provide a child-resistant medicament dispensing container. In an open configuration, as shown in  FIGS. 29 and 30 , pocket  514  is rotated relative to pocket  524  such that medicament dispensing container  512  rests flatly on a surface to facilitate ease of access to the contents of the cavity of container  512 . In one embodiment, medicament dispensing container  512  is sized to facilitate carrying and storage of printer paper, such as, for example, 9 inches by 12 inches. 
     Medicament dispensing container  512  includes a mechanism configured to connect pocket  514  with pocket  524  for disposal of the components of medicament dispensing container  512  in a closed configuration. In some embodiments, pocket  514  and/or pocket  524  is provided with indicia, such as, for example, instructions to aid a user patient in use of medicament dispensing container  512 . The instructions may be presented in the form of a graphic, such as, for example, a bulls eye, or text, such as, for example, “push here”. 
     Medicament dispensing container  512  includes locking mechanism  550 . Locking mechanism  550  includes a male engagement portion  552  and a female engagement portion  555 . In some embodiments, locking mechanism  550  audibly clicks to indicate a locked position. In some embodiments, locking mechanism  550  is provided with instructions to aid a patient in use of medicament dispensing container  512 . In some embodiments, the instructions may be presented in the form of a graphic, such as, for example, an arrow with a lock, or text, such as, for example, “slide to unlock”. In some embodiments, the instructions may be printed on locking mechanism  550 . Alternatively, in some embodiments, the instructions may be printed onto sidewall  518  adjacent locking mechanism  550 . 
     Medicament dispensing container  512  comprises one or more unit dose pages  560 , as shown in  FIGS. 23-26 , that store and/or contain one or more medications, such as, for example, a dose of at least one medication. The dose of medication(s) is enclosed and sealed in a plurality of receptacles  562 . In some embodiments, medicament dispensing container  512  includes a plurality of unit dose pages  560 . In one embodiment, the plurality of unit dose pages  560  is disposed in a trifold configuration, as shown in  FIG. 24 . In some embodiments, each unit dose page  560  encloses a different medication such that each medication that is part of a patient&#39;s dosage regimen is organized on separate unit dose pages  560 . In some embodiments, unit dose page  560  comprises receptacles  562  indicating a patient&#39;s daily dosage of medication held within unit dose page  560 . In some embodiments, unit dose page  560  comprises indicia  564 , disposed with and displayed from a predetermined area adjacent one or more receptacles  562 , indicating information regarding the medication enclosed within receptacles  562 . 
     In some embodiments, medicament dispensing container  512  comprises a disposable dispensing device that provides therapeutic and/or nutritional support to an animal by increasing compliance with a dosing regimen, as described herein. In some embodiments, medicament dispensing container  512  and/or one or more unit dose pages  560  include blister packs, which comprise a plurality of receptacles  562 . In some embodiments, each receptacle  562  accommodates a dosage unit and isolates that dosage unit from other dosage units. In some embodiments, a biologically-active substance within each dosage unit will not come into contact with the biologically-active substance of other dosage units. 
     In some embodiments, medicament dispensing container  512  and/or one or more unit dose pages  560  include a blister pack comprising at least one row of a plurality of receptacles  562  and/or areas including indicia  564 . In some embodiments, each area defines at least one receptacle  562 . In some embodiments, each receptacle  562  is designed to hold only one dosage unit having either only one biologically-active substance or multiple storage-compatible substances. In some embodiments, each receptacle  562  is designed to hold a plurality of dosage units. In one embodiment, as shown in  FIG. 26 , receptacles  562  are aligned such that receptacles  562   a  on one page  560   a  are configured for disposal between receptacles  562   b  within an opposing page  560   b  to facilitate closing of pages  560   a ,  560   b  with minimal for storage within medicament dispensing container  512 . 
     In some embodiments, each predetermined area including one or more receptacles  562  may have an independently removable or breakable seal. In some embodiments, each receptacle  562  is moisture resistant and independently sealed. In some embodiments, one or more receptacles  562  may comprise a blister pack including a push-through pack, which has a lid material of aluminum foil or aluminum foil laminate. In some embodiments, a base of one or more receptacles  562  may be plastic, such as, for example, PVC, polyamides, polyolefins, polyesters and laminates or multi-layered materials. In some embodiments, the lid foil of a receptacle  562  may be provided with a line of weakness in a region of each receptacle  562  such that the line of weakness may be a tab for gripping that enables a receptacle  562  to be exposed by manipulation of the lid foil. 
     In some embodiments, receptacle  562  may be made embossed, cast deep drawn or vacuum formed out of plastic, plastic laminates, plastic/paper laminates or plastic/metal foil laminates. In some embodiments, receptacle  562  comprises a barrier layer against gases and vapors, which may be fabricated from a metal foil such as an aluminum foil embedded in a plastic laminate or ceramic layers or metallic layers embedded between two plastic layers. 
     In some embodiments, a medication regimen can include a first dosage unit arrayed on a blister pack of receptacles  562  adjacent to a second dosage unit. In some embodiments, the medication regimen includes a first dosage unit disposed adjacent to a second dosage unit disposed with different receptacles  562 . 
     In some embodiments, unit dose page  560  comprises fourteen receptacles  562 . One dosage unit is enclosed in each receptacle  562 . Receptacles  562  are horizontally arranged in two rows adjacent to one another. In one embodiment, the rows are organized into weeks such that each row comprises seven receptacles  562 . Unit dose page  560  comprises indicia  564  indicating the time and order in which the medications are to be taken by the patient. Each receptacle  562  is labeled with an arrow having the day the dosage should be taken according to a dosage regimen. Indicia  564  are screen printed on unit dose page  560 . In some embodiments, indicia  564  may be hand written. Sections of unit dose page  560  are left blank to allow hand written notes or instructions by a patient, pharmacist or doctor. 
     In one embodiment, unit dose page  560  comprises twenty-eight receptacles  562 . One dosage unit is enclosed in each receptacle  562 . Receptacles  562  are vertically arranged in two groupings of two rows adjacent to one another. The groupings are organized into weeks such that each grouping comprises fourteen receptacles  562 . Unit dose page  560  comprises indicia  564  indicating the time and order in which the medications are to be taken by the patient. Each receptacle  562  is labeled with a number to indicate the day of a dosage regimen the medications should be taken. Indicia  564  includes graphics to indicate the time of day the medications should be taken. Indicia  564  are screen printed on unit dose page  560 . In some embodiments, indicia  564  may be hand written. Sections of unit dose page  560  are left blank to allow hand written notes or instructions by a patient, pharmacist or doctor. 
     In one embodiment, unit dose page  560  comprises fourteen receptacles  562 . One dosage unit is enclosed in each receptacle  562 . Receptacles  562  are vertically arranged in two rows oppositely arranged from one another. The rows are organized into weeks such that each row comprises seven receptacles  562 . Unit dose page  560  comprises indicia  564  indicating the time and order in which the medications are to be taken by the patient. Each receptacle  562  is labeled with a number to indicate the day a dosage regimen the medications should be taken. Indicia  564  are screen printed on unit dose page  560 . In some embodiments, indicia  564  may be hand written. Sections of unit dose page  560  are left blank to allow hand written notes or instructions by a patient, pharmacist or doctor. 
     In some embodiments, unit dose page  560  comprises indicia  564  to indicate the name and/or nature of the medications being administered. In some embodiments, indicia  564  include a list of possible side effects of the medications being administered. In some embodiments, indicia  564  provide instructions on how long a patient should take the medication being administered. 
     In some embodiments, medicament dispensing system  10  comprises one or more information inserts  570  to educate a patient about a medication being administered in the dosage regimen. In some embodiments, information insert  570  comprises indicia  572  to indicate the name and/or nature of the medicine being administered. In some embodiments, indicia  572  include a list of possible side effects of the medications being administered. In some embodiments, indicia  572  provide instructions on how long a patient should take the medication being administered. In some embodiments, medicament dispensing system  10  includes a notepad  576  configured to fit into the cavity created when container  512  is in the closed configuration to facilitate a doctor, pharmacist, health care personnel and/or patient creating personalized reminders and notes for a patient. 
     In some embodiments, insert  570  is printed onto a separate page to be viewed in tandem with page  560 . In some embodiments, insert  570  is disposed with pocket  514  and a first page  560  is disposed in pocket  524  such that when a first page  560  is viewed, the information on insert  570  can be viewed simultaneously 
     In one embodiment, as shown in  FIGS. 32-38 , medicament dispensing system  10 , similar to the systems and methods described herein, includes a medicament dispensing container  612 . Medicament dispensing container  612  includes a pocket  614  and a pocket  624 . Pocket  614  includes a bottom section  616 , a front sidewall  618 , and opposing sidewalls  620 . Walls  618 ,  620  define a surface  622 . Sidewalls  620  are disposed on opposing sides of bottom section  616  such that sidewall  618  extends between sidewalls  620 . 
     Pocket  624  includes a top section  626 , a front sidewall  628 , and opposing sidewalls  630 . Sidewalls  630  are disposed on opposing sides of top section  626  such that sidewall  628  extends between sidewalls  630 . Walls  628 ,  630  define a surface  632 . Surface  622  is configured to mate with surface  632  to close medicament dispensing container  612 . 
     In some embodiments, medicament dispensing container  612  includes a connecting portion, such as, for example, a spine  640 . Spine  640  extends between pocket  614  and pocket  624  such that pocket  624  is pivotable relative to pocket  614 . Pocket  624  is attached to spine  640  at an end opposite sidewall  628 , and pocket  614  is attached to spine  640  at an end opposite sidewall  618 . Pocket  624  is pivotable relative to pocket  614  between an open or non-locked configuration, such as, for example, a medication accessible configuration, as shown in  FIG. 34 , and a closed or locked configuration, such as, for example, a tamper resistant configuration, as shown in  FIG. 32 . In some embodiments, medicament dispensing container  612  is disposable in a closed, locked and non-tamper resistant configuration with a locking mechanism  650 , as described herein. 
     In some embodiments, pocket  624  is rotatable relative to pocket  614  through an angular range of 0 through 360 degrees. In a closed configuration, as shown in  FIG. 32 , spine  640 , sidewalls  618 ,  620 ,  628 ,  630 , and sections  616 ,  626  define a substantially enclosed cavity configured for disposal of unit dose pages  660  and/or information inserts  670  such that pocket  624  and pocket  614  prevent access to contents of medicament dispensing container  612 . In some embodiments, in a closed configuration, pocket  624  and pocket  614  provide a child-resistant medicament dispensing container. In an open configuration, as shown in  FIG. 34 , pocket  614  is rotated relative to pocket  624  such that medicament dispensing container  612  rests flatly on a surface to facilitate ease of access to the contents of the cavity of medicament dispensing container  612 . 
     Medicament dispensing container  612  includes a mechanism configured to connect pocket  614  with pocket  624  for disposal of the components of medicament dispensing container  612  in a closed configuration. In some embodiments, pocket  614  and/or pocket  624  is provided with indicia, such as, for example, instructions to aid a user patient in use of medicament dispensing container  612 . The instructions may be presented in the form of a graphic, such as, for example, a bulls eye, or text, such as, for example, “push here”. 
     Medicament dispensing container  612  includes locking mechanism  650  comprising a slide  654 , such as, for example, two slides  654 , disposed on opposite sides of pockets  614 ,  624  at a corner defined by front walls  618 ,  628  and sidewalls  620 ,  630 . Each slide  654  includes a male engagement portion, such as for example, a flange  656  configured to engage pocket  624 . Pocket  624  includes an outer surface  642  that defines slots  658 . Slots  658  extend a distance from sidewalls  620 ,  630  towards each other along front walls  618 ,  628 . Slots  658  are configured to facilitate translation of flanges  656  such that slides  654  are translated, in the direction shown by arrows A in  FIG. 33 , to move medicament dispensing container  612  to an open or non-locked configuration, and slides  654  are translated, in the direction shown by arrows B in  FIG. 32 , to a closed or locked configuration, such as, for example, a tamper resistant configuration. 
     In some embodiments, locking mechanism  650  audibly clicks to indicate a locked position. In some embodiments, locking mechanism  650  is provided with instructions to aid a patient in use of medicament dispensing container  612 . In some embodiments, the instructions may be presented in the form of a graphic, such as, for example, an arrow with a lock, or text, such as, for example, “slide to unlock”. In some embodiments, the instructions may be printed on locking mechanism  650 . Alternatively, in some embodiments, the instructions may be printed onto sidewall  618  adjacent locking mechanism  650 . 
     Medicament dispensing container  612  comprises one or more unit dose pages  660 , as shown in  FIG. 34 , which store and/or contain one or more medications, such as, for example, a dose of at least one medication. The dose of medication(s) is enclosed and sealed in a plurality of receptacles  662 . In some embodiments, medicament dispensing container  612  includes a plurality of unit dose pages  660 . In one embodiment, the plurality of unit dose pages  660  is disposed in a trifold configuration, as shown in  FIG. 34 . In some embodiments, each unit dose page  660  encloses a different medication such that each medication that is part of a patient&#39;s dosage regimen is organized on separate unit dose pages  660 . In some embodiments, unit dose page  660  comprises receptacles  662  indicating a patient&#39;s daily dosage of medication held within unit dose page  660 . In some embodiments, unit dose page  660  comprises indicia  664 , disposed with and displayed from a predetermined area adjacent one or more receptacles  662 , indicating information regarding the medication enclosed within receptacles  662 . 
     In some embodiments, medicament dispensing container  612  includes a plurality of medicament dispensing containers  612 , as shown in  FIGS. 36-38 , configured for disposal with a receptacle, such as, for example, an organizer  700 . Organizer  700  is divided into sections  704 . Sections  704  include compartments  706  and compartment  708  separated by partitions  710 . Each compartment  706  includes a wall  712  and openings  714 . In some embodiments, each compartment  706  is equally sized and configured. In some embodiments, compartment  708  is larger to store at least two medicament dispensing containers  612  in a top to bottom configuration to facilitate efficient storage of medicament dispensing containers, such as, for example, medicament dispensing containers  612 . In some embodiments, organizer  700  is configured for disposal of medicament dispensing containers  612  in a linear orientation. In some embodiments, stack organizer  700  is configured for disposal of medicament dispensing containers  612  in a staggered, offset, row or column orientation. 
     In one embodiment, organizer  700  includes a folder flap  720  attached to organizer  700  at a connecting portion, such as, for example, a spine  722 . Spine  722  is disposed such that flap  720  is pivotable relative to spine  722 . Flap  720  is pivotable relative to organizer  700  between an open or non-locked configuration, such as, for example a medication accessible configuration, and a closed or locked configuration, such as, for example, a tamper resistant configuration, similar to that described herein. 
     In one embodiment, as shown in  FIGS. 39-41 , medicament dispensing system  10 , similar to the systems and methods of use of medicament dispensing system  10  described herein, includes a medication packaging  812 . Medication packaging  812  includes a bottom portion  814 , a pair of oppositely positioned side walls  816 , a front wall  818  and a rear wall  820 . In one embodiment, medication packaging  812  is a foldable box in which portion  814  is formed from foldable portions of walls  816 ,  818 ,  820 . Walls  816  are spaced apart from one another by a first distance, and walls  818 ,  820  are spaced apart from one another by a second distance. In one embodiment, the first distance is greater than the second distance such that walls  816 ,  818  have a rectangular cross-sectional configuration. In other embodiments, the first and second distances are equal such that walls  816 ,  818  have a square cross-sectional configuration. Portion  814  and walls  816 ,  818 ,  820  define a cavity  822 . Cavity  822  is sized to receive medicaments stored in medication containers  840 , as discussed herein, as shown in  FIG. 41 . In one embodiment, cavity  822  receives an insert having a step-like profile (not shown) to provide a base for containers  840 . The insert provides bases of increasing height for consecutive containers  840  such that multiple containers  840  are visible to a user, as shown in  FIGS. 39-41 . 
     Wall  820  is taller than wall  818  to facilitate a patient&#39;s visibility of containers  840  held in cavity  822 . Walls  816  extend between walls  820  and  818  such that walls  816  have a sloped profile. In one embodiment, walls  816  include indicia  824  to differentiate containers  840  held in cavity  822 . In one embodiment, the indicia  824  include characters to identify corresponding containers  840 . Indicia  824  are screen printed onto walls  816 . In some embodiments, indicia  824  may be hand written. 
     In one embodiment, medication packaging  812  includes a retaining member, such as, for example, a strap  826 . Strap  826  extends from wall  820  and is configured to retain containers  840  in cavity  822 . Strap  826  includes tabs  828  sized to fit into slits  830  of wall  818 , as discussed herein. In one embodiment, strap  826  is made from an elastomeric material or a fabric and is flexible along its body. In one embodiment, strap  826  is made from a rigid material, such as, for example, cardboard and is partially flexible. For example, strap  826  may include bends  827  to allow flexibility at certain portions. In some embodiments, bends  827  are spaced along strap  826  to form a predefined shape, such as a shape to conform to containers  840  held within cavity  822 . 
     In some embodiments, strap  826  is movable between an unlocked configuration and a locked configuration. In the unlocked configuration, strap  826  is not engaged with medication packaging  812  such that containers  840  are readily accessible to a patient. In the locked configuration, tabs  828  are inserted into slits  830  to retain containers  840  in cavity  822 . When moving to the locked configuration, strap  826  is rotated toward wall  818  until tabs  828  are aligned with slits  830 . In some embodiments, tab  828  includes a length that is greater than the length of slit  830 . As medication packaging  812  is moved between an unlocked configuration and a locked configuration, engagement of tabs  828  with slits  830  causes tabs  828  to bow and/or flex to fit into slits  830 . 
     In one embodiment, strap  826  is configured to provide mechanical support for medication packaging  812  in the unlocked configuration. In one embodiment, as shown in  FIG. 41 , strap  826  is folded adjacent to wall  820  along bends  827  to define a support portion  832  of strap  826 . Bends  827  are spaced such that support portion  832  lies flat on a surface top adjacent portion  814 . Support portion  832  provides a wider base for medication packaging  812  to increase mechanical stability and prevent medication packaging  812  from being tipped. 
     In one embodiment, medicament dispensing system  10  includes at least one medication container  840  having an interior space to receive medications. Container  840  is movable between a closed configuration and a medication accessible configuration. Containers  840  include a stackable configuration to facilitate efficient storage of containers  840  with medication packaging  812 . In some embodiments, container  840  is configured for disposal of medications in a linear and/or axial orientation. In some embodiments, container  840  is configured for disposal of medications in a staggered, offset, row or column orientation. In some embodiments, container  840  comprises indicia displaying information regarding the medication enclosed within the interior space. 
     Medication packaging  812  is portable such that the user/patient transports and/or carries medication packaging  812  upon discharge. Strap  826  is moved from a locked configuration, as shown in  FIGS. 39 and 40 , to an unlocked configuration, as shown in  FIG. 41 . Tabs  828  are bowed and/or flexed to disengage slits  830  on front wall  818 . Strap  826  is rotated behind rear wall  820  and folded along creases  827  such that support portion  832  lies flat on a surface top adjacent to bottom portion  814  of medication packaging  812 . The contents of cavity  822 , which may include containers  840  and/or informational inserts, as described herein, are accessible to the user/patient, as shown in  FIG. 41 . The user/patient employs the components of medicament dispensing system  10 , for example, following direction via indicia printed on containers  840  for administering dosage units from containers  840  to facilitate user/patient compliance with the medication regimen in connection with treatment for the myocardial infarction. Strap  826  is rotated back to the locked configuration such that medication packaging  812  is disposable in a child-tamper resistant, locked configuration, as shown in  FIG. 39 , for storage and subsequent use. 
     In one embodiment, as shown in  FIGS. 42 and 43 , medicament dispensing system  10 , similar to the systems and methods of use of medicament dispensing system  10  described herein, includes a medicament storage device, such as, for example, medication packaging  912 . Medication packaging  912  includes a base portion  914  and columns  916 . In one embodiment, base portion  914  defines a rectangular shape and columns  916  are positioned at each corner of base portion  914 , as shown in  FIG. 42 . Columns  916  extend from each corner and along adjacent sides of base portion  914  to form a V-shaped cross section. Columns  916  and base portion  914  define a cavity  922 . Cavity  922  is sized to receive medicaments stored in medication containers  940 , similar to medication containers  840  described herein. 
     In one embodiment, base portion  914  includes flat surfaces  918 . Surfaces  918  are positioned adjacent columns  916  and form a bottom surface to be disposed with a stack of containers  940 . Base portion  914  includes a recess to allow a user to fit a finger under a container  940  disposed with surfaces  918  to remove one or more containers  940  from cavity  922 . In one embodiment, as shown in  FIG. 42 , packaging  912  comprises two pairs of recesses  920  that extend between opposite sides of base portion  914 . In other embodiments, recesses  920  may be variously configured. For example, in one embodiment, medication packaging  912  may comprise a single recess  920  or only one pair of oppositely positioned recesses  920 . 
     In one embodiment, medicament dispensing system  10  includes at least one medication container  940 . Container  940  has an interior space to receive medications, as described herein. Container  940  is movable between a closed configuration and a medication accessible configuration, similar to that described herein. Containers  940  include a stackable configuration to facilitate efficient storage of containers  940  in medication packaging  912 . In some embodiments, container  940  is configured for disposal of medications in a linear and/or axial orientation. In some embodiments, container  940  is configured for disposal of medications in a staggered, offset, row or column orientation. In some embodiments, container  940  comprises indicia displaying information regarding the medication enclosed within the interior space. 
     In one embodiment, as shown in  FIGS. 44-46 , medicament dispensing system  10 , similar to the systems and methods of use of medicament dispensing system  10  described herein, includes a medicament storage device, such as, for example, medication packaging  1012 . Medication packaging  1012  includes a base portion  1014  and partitions  1016 . In one embodiment, base portion  1014  defines a rectangular shape and includes a plurality of partitions  1016  extending from portion  1014 , as shown in  FIG. 44 . Portion  1014  includes a surface  1018  disposed with a one or more medication containers  1040 , similar to the medication containers described herein. Adjacent partitions  1016  extend parallel to one another to define a cavity  1022 . Cavity  1022  is sized to receive medicaments stored in medication containers  1040 , as discussed herein. 
     In one embodiment, medicament dispensing system  10  includes at least one medication container  1040 . Container  1040  has an interior space to receive medications, similar to that described herein. Container  1040  is movable between a closed configuration and a medication accessible configuration, similar to that described herein. In some embodiments, containers  1040  are configured for disposal of medications in a linear and/or axial orientation. In some embodiments, containers  1040  are configured for disposal of medications in a staggered, offset, row or column orientation. In some embodiments, container  1040  comprises indicia displaying information regarding the medication enclosed within the interior space. 
     In one embodiment, as shown in  FIGS. 47 and 48 , medicament dispensing system  10 , similar to the systems and methods of use of medicament dispensing system  10  described herein, includes a medicament storage device, such as, for example, medication packaging  1112 , similar to medication packaging described herein. Medication packaging  1112  includes a base portion  1114  and columns  1116  that define a cavity  1122 . Cavity  1122  is sized to receive medicaments stored in medication containers  1140 , similar to the medication containers described herein. 
     In one embodiment, as shown in  FIG. 49 , medicament dispensing system  10 , similar to the systems and methods of use of medicament dispensing system  10  described herein, includes a medicament storage device, such as, for example, medication packaging  1212 , similar to the medication packaging described herein. Medication packaging  1212  includes a base portion  1214  and partitions  1216  that define cavities  1222 . Cavities  1222  are sized to receive medicaments stored in medication containers  1240 , similar to the medication containers described herein. 
     In one embodiment, as shown in  FIGS. 50-52 , medicament dispensing system  10 , similar to the systems and methods of use of medicament dispensing system  10  described herein, includes a medicament storage device, such as, for example, medication packaging  1312 , similar to the medication packaging described herein. Medication packaging  1312  receives medicaments stored in medication containers  1340 , similar to the medication containers described herein. Medication packaging  1312  includes a strap  1326 , similar to the straps described herein. 
     It will be understood that various modifications may be made to the embodiments disclosed herein. Therefore, the above description should not be construed as limiting, but merely as exemplification of the various embodiments. Those skilled in the art will envision other modifications within the scope and spirit of the claims appended hereto.