Patent Publication Number: US-2019194760-A1

Title: Novel biomarkers

Description:
FIELD OF THE INVENTION 
     The present invention relates to methods of diagnosing, monitoring of a subject or determining the prognosis of a subject. In particular, the invention relates to a method of determining the prognosis of a cancer patient comprising the steps (a) determining the expression level of at least one marker gene selected from the group consisting of the marker genes as described herein in a sample of the cancer patient to obtain a gene expression profile; (b) determining the prognosis of the cancer patient based on the gene expression profile obtained in step (a). In addition, the present invention refers to kits, diagnostic compositions devices and microarrays for determining at least one marker gene and uses thereof. 
     BACKGROUND OF THE INVENTION 
     Technological advances have greatly increased our understanding of the molecular basis of diseases. In the past, biomarkers have been developed that can be used for a range of applications including predicting disease risk, diagnosis, predicting prognosis, identifying appropriate therapy for an individual, monitoring disease or for return of a disease, predicting the survival of a patient and other applications. 
     However, new diagnostic, prognostic and predictive biomarkers are necessary to improve disease prognosis and prediction. 
     In particular, in the treatment of cancer, for example lung cancer or prostate cancer, improved biomarkers are necessary. Lung cancer is the leading cause of cancer-related deaths world-wide and 85-90% of those malignancies are classified as non-small cell lung cancer (NSCLC). For decades, clinical outcomes of patients with advanced NSCLC were poor with 5-year survival rates of less than 5%. However, immunotherapeutic approaches, in particular checkpoint inhibitors, have recently dramatically impacted the field of cancer therapy. The aim of immunotherapy is to induce and activate host immune responses against the tumor. Antibodies blocking the interaction of inhibitory T cell receptors CTLA-4 or PD-1 with their ligands were demonstrated to improve survival rates in patients with metastasized melanoma and NSCLC. In addition, encouraging long lasting responses have been observed in a variety of solid tumors and hematologic malignancies after treatment with antibodies blocking PD-1 or PD-L1. Whereas these clinical results are highly encouraging, a substantial portion of patients fail to benefit from checkpoint inhibition treatment. Furthermore, immune-mediated adverse effects occur even in patients who do not respond to treatment. 
     Thus, there is a need for new biomarkers for prognosis and prediction in diseases, in particular in cancer, such as lung cancer or prostate cancer. 
     SUMMARY OF THE INVENTION 
     To address these need, the present invention relates to a method of diagnosing, monitoring of a subject or determining the prognosis of a subject comprising the steps of (a) determining the expression level of at least one marker gene selected from the group consisting of the genes set out in table 1 in a sample of the subject to obtain a gene expression profile; (b) diagnosing, monitoring of a subject or determining the prognosis of the subject based on the gene expression profile obtained in step (a). 
     In particular, the invention relates to a method of determining the prognosis of a cancer patient comprising the steps of 
     (a) determining the expression level of at least one marker gene selected from the group consisting of the marker genes set out in table 1 in a sample of the cancer patient to obtain a gene expression profile;
 
(b) determining the prognosis of the cancer patient based on the gene expression profile obtained in step (a).
 
     In specific embodiments, the at least one marker gene is selected from the group consisting of genes set out in table 2. In preferred embodiments, the at least one marker gene is selected from the group consisting of marker genes set out in table 3. In more preferred embodiments, the at least one marker gene is selected from group consisting of marker genes set out in table 4. In even more preferred embodiments, the at least one marker gene is selected from group consisting of marker genes set out in table 5. 
     In specific embodiments, the at least one marker gene is selected from the group consisting of genes set out in table 2B. In preferred embodiments, the at least one marker gene is selected from the group consisting of marker genes set out in table 3B. In more preferred embodiments, the at least one marker gene is selected from group consisting of marker genes set out in table 4B. In even more preferred embodiments, the at least one marker gene is selected from group consisting of marker genes set out in table 5B. 
     In some embodiments at least 10 marker genes are selected from table 1. Preferably at least 30 marker genes, more preferably at least 50 marker genes, most preferably at least 100 marker genes are selected from table 1. In some embodiments at least 10 marker genes are selected from table 2; preferably at least 30 marker genes, more preferably at least 50 marker genes, most preferably at least 100 marker genes are selected from table 2. In other embodiments at least 10 genes are selected from table 3; preferably at least 30 marker genes, more preferably at least 50 marker genes are selected from table 3. In further embodiments at least 10 genes are selected from table 4. Preferably at least 20 marker genes, more preferably at least 30 marker genes are selected from table 4. In some embodiments at least 10 marker genes are selected from table 5. 
     In some embodiments at least 10 marker genes are selected from table 2B; preferably at least 30 marker genes, more preferably at least 50 marker genes, most preferably at least 90 marker genes are selected from table 2B. In other embodiments at least 10 genes are selected from table 3B; preferably at least 30 marker genes, more preferably at least 40 marker genes are selected from table 3B. In further embodiments at least 10 genes are selected from table 4B. Preferably at least 20 marker genes, more preferably at least 25 marker genes are selected from table 4B. In some embodiments at least 8 marker genes are selected from table 5B. 
     In specific embodiments, the gene expression profile of step (a) is obtained by determining the difference of the expression level of the at least one marker gene measured before administration of the therapeutic agent and after administration of at least one dose of the therapeutic agent. 
     Typically, the therapeutic agent is any agent used for therapy of a disease, preferably of cancer or tumor diseases. Preferably the therapeutic agent is an immunostimulatory composition and/or a vaccine and/or an immunotherapeutic agent. 
     In a preferred embodiment, the immunostimulatory composition and/or vaccine comprises at least one antigen selected from the group consisting of MAGE-C1, MAGE-C2, NY-ESO-1, Survivin and 5T4. Preferably, the immunostimulatory composition and/or vaccine comprises the antigens MAGE-C1, MAGE-C2, NY-ESO-1, Survivin and 5T4 or fragments or variants thereof. 
     Typically, the antigen(s) are present as peptides or proteins and/or are encoded by at least one nucleotide sequence. In preferred embodiments, the antigen(s) are encoded by at least one mRNA molecule. 
     The invention refers particularly to the prognosis of lung cancer, more particularly to non-small cell lung cancer (NSCLC). 
     Typically, the sample of the patient comprises peripheral blood mono-nuclear cells (PBMCs). 
     In some embodiments, in step (b) a hierarchical clustering algorithm is applied. 
     A further aspect of the invention relates to a kit, diagnostic composition or device for the analysis of at least one marker gene set out in table 1 comprising at least one primer and/or probe selective for determining the expression level of at least one marker gene set out in table 1. The kit, diagnostic composition or device may further comprise an enzyme for primer elongation, nucleotides and/or labeling agents. Also contemplated is the use of said kit, diagnostic composition or device for determining the prognosis of a cancer patient. 
     A further aspect of the invention relates to a microarray, comprising at least one probe selective for determining the expression level of at least one marker gene set out in table 1 and the use of said microarray for determining the prognosis of a cancer patient. 
     More specifically, the invention refers to a method of determining the prognosis of a patient comprising the steps of
         (a) determining the expression level of at least 30 marker genes selected from the group consisting of the marker genes set out in table 4 in a sample of the patient to obtain a gene expression profile;   (b) determining the prognosis of the patient based on the gene expression profile obtained in step (a).       

     The inventor found out that by the 30 marker genes of table 4 is possible to classify cancer patients ( FIG. 3  C). In a specific embodiment, the patient is a lung cancer patient, preferably a NSCLC patient. 
     In specific embodiments further marker genes such as least 10 additional marker genes, preferably at least 20 additional marker genes, more preferably at least 70 additional marker genes are selected from table 1, table 2 or table 3 are employed for the determining the prognosis of the patient. 
     The invention further refers to a method of determining the prognosis of a patient comprising the steps of
         (a) determining the expression level of at least one marker gene selected from the group consisting of the marker genes set out in table 11 in a sample of the patient to obtain a gene expression profile;   (b) determining the prognosis of the patient based on the gene expression profile obtained in step (a).       

     The inventors found that the marker genes set out in tables 11 to 15 are particular suitable to classify both lung cancer and prostate cancer patients. Therefore, the patient may be cancer or tumor patient, in particular a lung cancer or prostate cancer patient. In a specific embodiment, the cancer patient is a NSCLC cancer or prostate cancer patient. 
     In specific embodiments the at least one marker genes is selected from the group consisting of marker genes set out in table 12, table 13, table 14 or table 15. 
     In specific embodiments least 10 marker genes, preferably at least 30 marker genes, more preferably at least 50 marker genes, most preferably at least 100 marker genes are selected from table 11 or table 12. In a further embodiment, at least 10 marker genes, preferably at least 30 marker genes, more preferably at least 50 marker genes are selected from table 13. In another embodiment at least 10 marker genes, preferably at least 20 marker genes, more preferably at least 30 marker genes are selected from the group consisting of from table 14. 
     In some embodiments, the expression level of at least one marker gene is measured before administration and/or after administration of at least one dose of a therapeutic agent. Typically, the therapeutic agent is an immunostimulatory composition and/or a vaccine and/or an immunotherapeutic agent. In one embodiment, the immunostimulatory composition and/or vaccine comprises at least one antigen selected from the group consisting of MAGE-C1, MAGE-C2, NY-ESO-1, Survivin, 5T4, PSA, PSMA, PSCA, STEAP, PAP and MUC1 or fragments or variants thereof. In a specific embodiment, the immunostimulatory composition and/or vaccine comprises the antigens (i) MAGE-C1, MAGE-C2, NY-ESO-1, Survivin and 5T4 or fragments or variants thereof; or (ii) PSA, PSMA, PSCA, STEAP, PAP and MUC1 or fragments or variants thereof. 
     Accordingly, a further aspect of the invention refers to a kit, diagnostic composition or device for the analysis of at least one marker gene set out in table 11 comprising at least one primer and/or probe selective for determining the expression level of at least one marker gene set out in table 11. 
     Another aspect refers to a microarray, comprising at least one probe selective for determining the expression level of at least one marker gene set out in table 11. 
     Another aspect of the invention refers to a method of determining the prognosis of a patient comprising the steps of
         (a) determining the expression level of at least one marker gene selected from the group consisting of the marker genes set out in table 6 in a sample of the patient to obtain a gene expression profile;   (b) determining the prognosis of the patient based on the gene expression profile obtained in step (a).       

     The inventors found that the marker genes set out in tables 6 to 10 are particularly suitable to classify prostate cancer patients. Accordingly, the patient may be a cancer or tumor patient, in particular a prostate cancer patient. Therefore, in one embodiment, the immunostimulatory composition and/or vaccine comprises at least one antigen selected from the group consisting of PSA, PSMA, PSCA, STEAP, PAP and MUC1 or fragments or variants thereof. 
     Accordingly, another aspect of the invention refers to a kit, diagnostic composition or device for the analysis of at least one marker gene set out in table 6 comprising at least one primer and/or probe selective for determining the expression level of at least one marker gene set out in table 6. 
     An additional aspect refers to a microarray, comprising at least one probe selective for determining the expression level of at least one marker gene set out in table 6. 
    
    
     
       BRIEF DESCRIPTION OF THE FIGURES 
         FIG. 1 : Transcriptional changes post treatment cluster patients into distinct groups. Week 5 to 0 BTM activity score differences were calculated and unsupervised hierarchical clustering was performed. 
         FIG. 2 : Patients with NK and T cell BTM enrichment post CV9201 treatment are associated with a prolonged survival. Kaplan-Meier curves for overall survival (A) and progression-free survival (C) are shown for patients belonging to cluster 1, 2a and 2b. Overall survival (B) and progression-free survival rates (D) are shown for patients belonging to cluster 1 compared to patients belonging to cluster 2. Log-rank test was performed to calculate the hazard ratio and p value. 
         FIG. 3 . Identification of short-term survivors using hierarchical clustering on gene expression differences between post-vaccine time point week 5 and baseline week 0. Genes were ranked based on their ability to differentiate between patients derived from cluster 1 and patients derived from cluster 2. Top 100 (A), top 50 (B), or top 30 (C) genes were selected, and gene expression differences between week 5 and 0 were calculated followed by average-linkage hierarchical clustering. Clustering trees of patients are shown and short-term survivors are highlighted. 
         FIG. 4 : Transcriptional modules consistent with a T and NK cell profile are enriched at week 6 post initiation of CV9104 treatment. Results from gene set enrichment analyses contrasting post treatment week 6 samples to baseline samples are shown for cohorts A, B, C and A&amp;B combined. The top 10 most enriched modules are presented. 
     
    
    
     DEFINITIONS 
     For the sake of clarity and readability, the following definitions are provided. Any technical feature mentioned for these definitions may be read on each and every embodiment of the invention. Additional definitions and explanations may be specifically provided in the context of these embodiments. Unless defined otherwise, all technical and scientific terms used herein generally have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. Generally, the nomenclature used herein and the laboratory procedures in cell culture, molecular genetics, organic chemistry, and nucleic acid chemistry and hybridization are those well known and commonly employed in the art. Standard techniques are used for molecular biotechnology assays. The techniques and procedures are generally performed according to conventional methods in the art and various general references (e.g., Sambrook et al., 1989, Molecular Cloning: A Laboratory Manual, 2d ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.), which are provided throughout this document. 
     Marker, marker gene: The terms “marker” or “maker gene”, can be used interchangeably and relate to a gene, genetic unit or sequence (a nucleotide sequence or amino acid or protein sequence) as defined herein, the term also refers to any expression product of said genetic unit or sequence, in particular mRNA transcript, a polypeptide or protein encoded by the transcript or fragments thereof, as well as homologous derivatives thereof as described herein above. In particular, the term marker gene refers to a gene set out in table 1. Preferably, the marker gene is selected from the group consisting of genes set out in table 2, more preferably from the group consisting of genes set out in table 3, even more preferably from group consisting of genes set out in table 4, most preferably at least from group consisting of genes set out in table 5. 
     Subject, individual, patient: A subject, individual or patient according to the present invention is an animal, preferably a mammal, more preferably a human being. A subject, individual or patient according to the present invention is an animal, preferably a mammal, more preferably a human being. The method also relates to healthy subjects and to patients. In particular, the method of the invention refers to patients who are cancer or tumor patients. A cancer or tumor patient is a subject or individual who is diagnosed as having cancer or tumor. 
     non-small-cell lung cancer (NSCLC): non-small-cell lung cancer as used herein refers to the three main sub-types of non-small-cell lung cancer including, without being restricted thereto, squamous cell lung carcinoma, adenocarcinoma and large cell lung carcinoma. 
     determining the prognosis of a patient: The term “determining the prognosis of a patient” (and also indication specific terms such as “determining the prognosis of a cancer or tumor patient”) as used herein refers to the prediction of the course or outcome of a diagnosed or detected disease, e.g. during a certain period of time, before a treatment, during a treatment or after a treatment. The term also refers to a determination of chance of survival or recovery from the disease, as well as to a prediction of the expected survival time of a subject. A prognosis may, specifically, involve establishing the likelihood for survival of a subject during a period of time into the future, such as 6 months, 1 year, 2 years, 3 years, 5 years, 10 years or any other period of time. In a specific embodiment the prognosis may involve predicting the survival of a patient, i.e. whether the survival of a subject is shorter than or equal to a certain period of time, such as 6 months, 12 months or 15 months or any other period of time, or longer than a certain period of time, such as 6 months, 12 months, 15 months or 30 months or any other period of time. For example, the prognosis may involve a prediction whether the survival time of a cancer patient is equal or shorter than 15 months or whether the survival time of a cancer patient is longer than 15 months. 
     Obtain a gene expression profile: The gene expression profile is obtained by relating the expression level of the at least one marker gene to a reference value. The reference value may be for example the expression level of a control gene measured in the same sample of the individual. Alternatively, the reference value may be a control expression level derived from a healthy control sample or a sample from a pathological sample (of the disease of interest). The pathological sample may be for example from a patient with tumor or cancer (e.g. progressive tumor or non-progressive tumor). Alternatively, the reference value may be the expression level measured at a different time point in the same patient. The different time point may be a different treatment stage, e.g. before treatment, during treatment, after treatment, after the administration of a certain amount of treatment doses. The different time point may be any type of periodical time segment, such as one week, 2 weeks one months, 2, 3, 4, 5, 6, 7, 8, 10, 11 or 12 months, 1.5 years, 2, 3, 4, 5, 6, 7, 8, 9, 10 years ago. In a preferred embodiment the gene expression profile is obtained by relation of the expression level of the at least one marker gene after administration of at least one dose of therapeutic agent to the expression level of the at least one marker gene before administration of the therapeutic agent. 
     Monitoring: The term “monitoring” as used herein relates to the accompaniment of a diagnosed or detected disease or disorder, e.g. during a treatment procedure or during a certain period of time, typically during 2 months, 3 months, 4 months, 6 months, 1 year, 2 years, 3 years, 5 years, 10 years, or any other period of time, changes of these sates of disease may be detected by comparing the expression. The term “accompaniment” means that states of disease as defined herein above and, in particular level of the marker genes of the present invention in a sample are measured and a gene expression profile is obtained by comparison to a reference value in any type of periodical time segment, e.g. every week, every 2 weeks, every month, every 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 or 12 month, every 1.5 year, every 2, 3, 4, 5, 6, 7, 8, 9 or 10 years, during any period of time, e.g. during 2 weeks, 3 weeks, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 months, 1.5, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15 or 20 years, respectively. 
     Diagnosing: The term “diagnosing” as used herein means that a patient or subject may be considered to be suffering from a disease. In particular, term “diagnosing” as used herein means that a patient or subject may be considered to be suffering from a disease based on the marker gen expression profile of the present invention. The term “diagnosing” also refers to the conclusion reached through that comparison process. 
     Reference gene: The term “reference gene” or “control gene” as used herein refers to any suitable gene, e.g. to any steadily expressed and continuously detectable gene, gene product, expression product, protein or protein variant in the organism of choice. The term also includes gene products such as expressed proteins, peptides, polypeptides, as well as modified variants thereof. The invention hence also includes reference proteins derived from a reference gene. Also encompassed are all kinds of transcripts derivable from the reference gene as well as modifications thereof or secondary parameters linked thereto. Alternatively, or additionally, other reference parameters may also be used for reference purposes, e.g. metabolic concentrations, cell sizes etc. 
     Microarray: A (DNA) microarray (also commonly known as DNA chip or biochip) is a collection of microscopic DNA spots attached to a solid surface. DNA microarrays are used to measure the expression levels of large numbers of genes simultaneously or to genotype multiple regions of a genome. Each DNA spot contains picomoles (10-12 moles) of a specific DNA sequence, known as probes (or reporters or oligos). These can be a short section of a gene or other DNA element that are used to hybridize a nucleic acid sample (called target) under high-stringency conditions. Probe-target hybridization is usually detected and quantified by detection of fluorophore-, silver-, or chemiluminescence-labeled targets to determine relative abundance of nucleic acid sequences in the target. A “microarray” is a linear or two-dimensional array of discrete regions, each having a defined area, formed on the surface of a generally solid support such as, but not limited to, glass, plastic, or synthetic membrane. The density of the discrete regions on a microarray is determined by the total numbers of immobilized oligonucleotides to be detected on the surface of a single solid phase support, such as at least about 50/cm2, at least about 100/cm2, at least about 500/cm2, but below about 1,000/cm2 in some embodiments. The arrays may contain less than about 500, about 1000, about 1500, about 2000, about 2500, or about 3000 immobilized oligonucleotides in total. As used herein, a DNA microarray is an array of nucleic acids e.g. oligonucleotides or oligonucleotides placed on a chip or other surfaces used to hybridize to amplified or cloned oligonucleotides from a sample. Because the position of each particular group of oligonucleotides in the array is known, the identities of a sample oligonucleotides can be determined based on their binding to a particular position in the microarray. 
     Probe: In molecular biology, a hybridization probe is a fragment of DNA or RNA of variable length. It can be used in DNA or RNA samples to detect the presence of nucleotide sequences (the target) that are complementary to the nucleic acid sequence in the probe. The probe thereby hybridizes to single-stranded nucleic acid (DNA or RNA) whose base sequence allows probe-target base pairing due to complementarity between the probe and target. 
     Amplify: The term “amplify” is used in the broad sense to mean creating an amplification product can be made enzymatically with DNA or RNA polymerases. “Amplification,” as used herein, generally refers to the process of producing multiple copies of a desired sequence, particularly those of a sample. “Multiple copies” mean at least 2 copies. A “copy” does not necessarily mean perfect sequence complementarity or identity to the template sequence. It is possible to further use any sequencing method known in the art to identify the sequences of marker genes. 
     Protein: A protein typically comprises one or more peptides or polypeptides. A protein is typically folded into a 3-dimensional form, which may be required for the protein to exert its biological function. The sequence of a protein or peptide is typically understood to be the order, i.e. the succession of its amino acids. 
     Peptide: A peptide or polypeptide is typically a polymer of amino acid monomers, linked by peptide bonds. It typically contains less than 50 monomer units. Nevertheless, the term peptide is not a disclaimer for molecules having more than 50 monomer units. Long peptides are also called polypeptides, typically having between 50 and 600 monomeric units. 
     Fragment or part of a protein: Fragments or parts of a protein in the context of the present invention are typically understood to be peptides corresponding to a continuous part of the amino acid sequence of a protein, preferably having a length of about 6 to about 20 or even more amino acids, e.g. parts as processed and presented by MHC class I molecules, preferably having a length of about 8 to about 10 amino acids, e.g. 8, 9, or 10, (or even 11, or 12 amino acids), or fragments as processed and presented by MHC class II molecules, preferably having a length of about 13 or more amino acids, e.g. 13, 14, 15, 16, 17, 18, 19, 20 or even more amino acids, wherein these fragments may be selected from any part of the amino acid sequence. These fragments are typically recognized by T cells in form of a complex consisting of the peptide fragment and an MHC molecule, i.e. the fragments are typically not recognized in their native form. Fragments or parts of the proteins as defined herein may also comprise epitopes or functional sites of those proteins. Preferably, fragments or parts of a proteins in the context of the invention are antigens, particularly immunogens, e.g. antigen determinants (also called ‘epitopes’), or do have antigenic characteristics, eliciting an adaptive immune response. Therefore, fragments of proteins or peptides may comprise at least one epitope of those proteins or peptides. Furthermore, also domains of a protein, like the extracellular domain, the intracellular domain or the transmembrane domain, and shortened or truncated versions of a protein may be understood to comprise a fragment of a protein. 
     RNA, mRNA: RNA is the usual abbreviation for ribonucleic acid. It is a nucleic acid molecule, i.e. a polymer consisting of nucleotide monomers. These nucleotides are usually adenosine-monophosphate, uridine-monophosphate, guanosine-monophosphate and cytidine-monophosphate monomers, which are connected to each other along a so-called backbone. The backbone is formed by phosphodiester bonds between the sugar, i.e. ribose, of a first and a phosphate moiety of a second, adjacent monomer. The specific order of the monomers, i.e. the order of the bases linked to the sugar/phosphate-backbone, is called the RNA-sequence. Usually RNA may be obtainable by transcription of a DNA-sequence, e.g., inside a cell. In eukaryotic cells, transcription is typically performed inside the nucleus or the mitochondria. In vivo, transcription of DNA usually results in the so-called premature RNA, which has to be processed into so-called messenger-RNA, usually abbreviated as mRNA. Processing of the premature RNA, e.g. in eukaryotic organisms, comprises a variety of different posttranscriptional-modifications such as splicing, 5′-capping, polyadenylation, export from the nucleus or the mitochondria and the like. The sum of these processes is also called maturation of RNA. The mature messenger RNA usually provides the nucleotide sequence that may be translated into an amino acid sequence of a particular peptide or protein. Typically, a mature mRNA comprises a 5′-cap, optionally a 5′UTR, an open reading frame, optionally a 3′UTR and a poly(A) sequence. Aside from messenger RNA, several non-coding types of RNA exist which may be involved in regulation of transcription and/or translation, and immunostimulation. The term “RNA” further encompass other coding RNA molecules, such as viral RNA, retroviral RNA and replicon RNA, small interfering RNA (siRNA), antisense RNA, CRISPR RNA, ribozymes, aptamers, riboswitches, immunostimulating RNA, transfer RNA (tRNA), ribosomal RNA (rRNA), small nuclear RNA (snRNA), small nucleolar RNA (snoRNA), microRNA (miRNA), and Piwi-interacting RNA (piRNA). 
     DNA: DNA is the usual abbreviation for deoxyribonucleic acid. It is a nucleic acid molecule, i.e. a polymer consisting of nucleotide monomers. These nucleotides are usually deoxy-adenosine-monophosphate, deoxy-thymidine-monophosphate, deoxy-guanosine-monophosphate and deoxy-cytidine-monophosphate monomers which are—by themselves—composed of a sugar moiety (deoxyribose), a base moiety and a phosphate moiety, and polymerized by a characteristic backbone structure. The backbone structure is, typically, formed by phosphodiester bonds between the sugar moiety of the nucleotide, i.e. deoxyribose, of a first and a phosphate moiety of a second, adjacent monomer. The specific order of the monomers, i.e. the order of the bases linked to the sugar/phosphate-backbone, is called the DNA-sequence. DNA may be single-stranded or double-stranded. In the double stranded form, the nucleotides of the first strand typically hybridize with the nucleotides of the second strand, e.g. by A/T-base-pairing and G/C-base-pairing. 
     Sequence of a nucleic acid molecule/nucleic acid sequence: The sequence of a nucleic acid molecule is typically understood to be the particular and individual order, i.e. the succession of its nucleotides. 
     Sequence of amino acid molecules/amino acid sequence: The sequence of a protein or peptide is typically understood to be the order, i.e. the succession of its amino acids. 
     Vaccine: A vaccine is a biological preparation that provides active acquired immunity to a particular disease. A vaccine typically contains an agent comprising an antigen which induces an adaptive immune response. 
     Immunotherapeutic agents: The term immunotherapeutic agent refers to agents capable of modulating the components of the immune system. Examples of immunotherapeutic agents are without limitation dendritic cells, T cells, antibodies, checkpoint modulators or cytokines, chemokines, interleukins, immunostimulatory agents and adjuvants. Immunotherapeutic agents include checkpoint modulators, therapeutic antibodies, immune cell therapy, T cell receptors (including CAR T cell therapy), immune system modulators such as cytokines and chemokines and vaccines. 
     Antigen: In the context of the present invention “antigen” refers typically to a substance, which may be recognized by the immune system, preferably by the adaptive immune system, and is capable of triggering an antigen-specific immune response, e.g. by formation of antibodies and/or antigen-specific T cells as part of an adaptive immune response. Typically, an antigen may be or may comprise a peptide or protein which may be presented by the MHC to T-cells and comprises at least one epitope. In particular, the antigen may be a pathogenic antigen or a tumor antigen. 
     Tumor antigens: In a further embodiment, the mRNA according to the present invention may encode a protein or a peptide, which comprises a peptide or protein comprising a tumor antigen, a fragment, variant or derivative of said tumor antigen, preferably, wherein the tumor antigen is a melanocyte-specific antigen, a cancer-testis antigen or a tumor-specific antigen, preferably a CT-X antigen, a non-X CT-antigen, a binding partner for a CT-X antigen or a binding partner for a non-X CT-antigen or a tumor-specific antigen, more preferably a CT-X antigen, a binding partner for a non-X CT-antigen or a tumor-specific antigen or a fragment, variant or derivative of said tumor antigen; and wherein each of the nucleic acid sequences encodes a different peptide or protein; and wherein at least one of the nucleic acid sequences encodes for 1A01_HLA-A/m; 1A02; 5T4; ACRBP; AFP; AKAP4; alpha-actinin-_4/m; alpha-methylacyl-coenzyme_A_racemase; ANDR; ART-4; ARTC1/m; AURKB; B2MG; B3GN5; B4GN1; B7H4; BAGE-1; BASI; BCL-2; bcr/abl; beta-catenin/m; BING-4; BIRC7; BRCA1/m; BY55; calreticulin; CAMEL; CASP-8/m; CASPA; cathepsin_B; cathepsin_L; CD1A; CD1B; CD1C; CD1D; CD1E; CD20; CD22; CD276; CD33; CD3E; CD3Z; CD44_Isoform_1; CD44_Isoform_6; CD4; CD52; CD55; CD56; CD80; CD86; CD8A; CDC27/m; CDE30; CDK4/m; CDKN2A/m; CEA; CEAM6; CH3L2; CLCA2; CML28; CML66; COA-1/m; coactosin-like_protein; collagen_XXIII; COX-2; CP1B1; CSAG2; CT45A1; CT55; CT-_9/BRD6; CTAG2_Isoform_LAGE-1A; CTAG2_Isoform_LAGE-1B; CTCFL; Cten; cyclin_B1; cyclin_D1; cyp-B; DAM-10; DEP1A; E7; EF1A2; EFTUD2/m; EGFR; EGLN3; ELF2/m; EMMPRIN; EpCam; EphA2; EphA3; ErbB3; ERBB4; ERG; ETV6; EWS; EZH2; FABP7; FCGR3A_Version_1; FCGR3A_Version_2; FGF5; FGFR2; fibronectin; FOS; FOXP3; FUT1; G250; GAGE-1; GAGE-2; GAGE-3; GAGE-4; GAGE-5; GAGE-6; GAGE7b; GAGE-8_(GAGE-2D); GASR; GnT-V; GPC3; GPNMB/m; GRM3; HAGE; hepsin; Her2/neu; HLA-A2/m; homeobox_NKX3.1; HOM-TES-85; HPG1; HS71A; HS71B; HST-2; hTERT; iCE; IF2B3; IL10; IL-13Ra2; IL2-RA; IL2-RB; IL2-RG; IL-5; IMP3; ITA5; ITB1; ITB6; kallikrein-2; kallikrein-4; KI20A; KIAA0205; KIF2C; KK-LC-1; LDLR; LGMN; LIRB2; LY6K; MAGA5; MAGA8; MAGAB; MAGE-A10; MAGE-A12; MAGE-A1; MAGE-A2; MAGE-A3; MAGE-A4; MAGE-A6; MAGE-A9; MAGE-B10; MAGE-B16; MAGE-B17; MAGE-B1; MAGE-B2; MAGE-B3; MAGE-B4; MAGE-B5; MAGE-B6; MAGE-C1; MAGE-C2; MAGE-C3; MAGE-D1; MAGE-D2; MAGE-D4; MAGE-_E1; MAGE-E1_(MAGE1); MAGE-E2; MAGE-F1; MAGE-H1; MAGEL2; mammaglobin_A; MART-1/melan-A; MART-2; MC1_R; M-CSF; mesothelin; MITF; MMP1_1; MMP7; MUC-1; MUM-1/m; MUM-2/m; MYCN; MYO1A; MYO1B; MYO1C; MYO1D; MYO1E; MYO1F; MYO1G; MYO1H; NA17; NA88-A; Neo-PAP; NFYC/m; NGEP; NPM; NRCAM; NSE; NUF2; NY-ESO-1; OA1; OGT; OS-9; osteocalcin; osteopontin; p53; PAGE-4; PAI-1; PAI-2; PAP; PATE; PAX3; PAX5; PD1L1; PDCD1; PDEF; PECA1; PGCB; PGFRB; Pim-1_-Kinase; Pin-1; PLAC1; PMEL; PML; POTEF; POTE; PRAME; PRDX5/m; PRM2; prostein; proteinase-3; PSA; PSB9; PSCA; PSGR; PSM; PTPRC; RAB8A; RAGE-1; RARA; RASH; RASK; RASN; RGS5; RHAMM/CD168; RHOC; RSSA; RU1; RU2; RUNX1; S-100; SAGE; SART-_1; SART-2; SART-3; SEPR; SERPINB5; SIA7F; SIA8A; SIAT9; SIRT2/m; SOX10; SP17; SPNXA; SPXN3; SSX-1; SSX-2; SSX3; SSX-4; ST1A1; STAG2; STAMP-1; STEAP-1; Survivin-2B; survivin; SYCP1; SYT-SSX-1; SYT-SSX-2; TARP; TCRg; TF2AA; TGFB1; TGFR2; TGM-4; TIE2; TKTL1; TPI/m; TRGV11; TRGV9; TRPC1; TRP-p8; TSG10; TSPY1; TVC_(TRGV3); TX101; tyrosinase; TYRP1; TYRP2; UPA; VEGFR1; WT1; and XAGE1, and a immunoglobulin idiotype of a lymphoid blood cell or a T cell receptor idiotype of a lymphoid blood cell, or a fragment, variant or derivative of said tumor antigen; preferably survivin or a homologue thereof, an antigen from the MAGE-family or a binding partner thereof or a fragment, variant or derivative of said tumor antigen. 
     Particularly preferred in this context are the tumor antigens NY-ESO-1, 5T4, MAGE-C1, MAGE-C2, Survivin, Muc-1, PSA, PSMA, PSCA, STEAP and PAP. 
     Most preferred is the combination of the antigens NY-ESO-1, 5T4, MAGE-C1, MAGE-C2, and Survivin. 
     Therapeutic proteins: Therapeutic proteins as defined herein are peptides or proteins which are beneficial for the treatment of any inherited or acquired disease or which improves the condition of an individual. Particularly, therapeutic proteins plays a big role in the creation of therapeutic agents that could modify and repair genetic errors, destroy cancer cells or pathogen infected cells, treat immune system disorders, treat metabolic or endocrine disorders, among other functions. Furthermore adjuvant proteins, therapeutic antibodies are encompassed by therapeutic proteins and also hormone replacement therapy which is e.g. used in the therapy of women in the menopause. In newer approaches somatic cells of a patient are used to reprogram them into pluripotent stem cells which replace the disputed stem cell therapy. Also these proteins used for reprogramming of somatic cells or used for differentiating of stem cells are defined herein as therapeutic proteins. Furthermore therapeutic proteins may be used for other purposes e.g. wound healing, tissue regeneration, angiogenesis, etc. 
     Therefore therapeutic proteins can be used for various purposes including treatment of various diseases like e.g. infectious diseases, neoplasms (e.g. cancer or tumor diseases), diseases of the blood and blood-forming organs, endocrine, nutritional and metabolic diseases, diseases of the nervous system, diseases of the circulatory system, diseases of the respiratory system, diseases of the digestive system, diseases of the skin and subcutaneous tissue, diseases of the musculoskeletal system and connective tissue, and diseases of the genitourinary system, independently if they are inherited or acquired. 
     These and other proteins are understood to be therapeutic, as they are meant to treat the subject by replacing its defective endogenous production of a functional protein in sufficient amounts. Accordingly, such therapeutic proteins are typically mammalian, in particular human proteins. 
     Furthermore, adjuvant or immunostimulating proteins are also encompassed in the term therapeutic proteins. Adjuvant or immunostimulating proteins may be used in this context to induce, alter or improve an immune response in an individual to treat a particular disease or to ameliorate the condition of the individual. 
     In this context, adjuvant proteins may be selected from mammalian, in particular human adjuvant proteins, which typically comprise any human protein or peptide, which is capable of eliciting an innate immune response (in a mammal), e.g. as a reaction of the binding of an exogenous TLR ligand to a TLR. More preferably, human adjuvant proteins are selected from the group consisting of proteins, which are components and ligands of the signalling networks of the pattern recognition receptors including TLR, NLR and RLH, including TLR1, TLR2, TLR3, TLR4, TLR5, TLR6, TLR7, TLR8, TLR9, TLR10, TLR11; NOD1, NOD2, NOD3, NOD4, NOD5, NALP1, NALP2, NALP3, NALP4, NALP5, NALP6, NALP6, NALP7, NALP7, NALP8, NALP9, NALP10, NALP11, NALP12, NALP13, NALP14,1 IPAF, NAIP, CIITA, RIG-I, MDA5 and LGP2, the signal transducers of TLR signaling including adaptor proteins including e.g. Trif and Cardif; components of the Small-GTPases signalling (RhoA, Ras, Rac1, Cdc42, Rab etc.), components of the PIP signalling (PI3K, Src-Kinases, etc.), components of the MyD88-dependent signalling (MyD88, IRAK1, IRAK2, IRAK4, TIRAP, TRAF6 etc.), components of the MyD88-independent signalling (TICAM1, TICAM2, TRAF6, TBK1, IRF3, TAK1, IRAK1 etc.); the activated kinases including e.g. Akt, MEKK1, MKK1, MKK3, MKK4, MKK6, MKK7, ERK1, ERK2, GSK3, PKC kinases, PKD kinases, GSK3 kinases, JNK, p38MAPK, TAK1, IKK, and TAK1; the activated transcription factors including e.g. NF-kB, c-Fos, c-Jun, c-Myc, CREB, AP-1, Elk-1, ATF2, IRF-3, IRF-7. 
     Mammalian, in particular human adjuvant proteins may furthermore be selected from the group consisting of heat shock proteins, such as HSP10, HSP60, HSP65, HSP70, HSP75 and HSP90, gp96, Fibrinogen, TypIII repeat extra domain A of fibronectin; or components of the complement system including C1q, MBL, C1r, C1s, C2b, Bb, D, MASP-1, MASP-2, C4b, C3b, C5a, C3a, C4a, C5b, C6, C7, C8, C9, CR1, CR2, CR3, CR4, C1qR, C1INH, C4 bp, MCP, DAF, H, I, P and CD59, or induced target genes including e.g. Beta-Defensin, cell surface proteins; or human adjuvant proteins including trif, flt-3 ligand, Gp96 or fibronectin, etc., or any species homolog of any of the above human adjuvant proteins. 
     Mammalian, in particular human adjuvant proteins may furthermore comprise cytokines which induce or enhance an innate immune response, including IL-1 alpha, IL1 beta, IL-2, IL-6, IL-7, IL-8, IL-9, IL-12, IL-13, IL-15, IL-16, IL-17, IL-18, IL-21, IL-23, TNFalpha, IFNalpha, IFNbeta, IFNgamma, GM-CSF, G-CSF, M-CSF; chemokines including IL-8, IP-10, MCP-1, MIP-1alpha, RANTES, Eotaxin, CCL21; cytokines which are released from macrophages, including IL-1, IL-6, IL-8, IL-12 and TNF-alpha; as well as IL-1R1 and IL-1 alpha. 
     Therapeutic proteins for the treatment of blood disorders, diseases of the circulatory system, diseases of the respiratory system, cancer or tumor diseases, infectious diseases or immunedeficiencies or adjuvant proteins are typically proteins of mammalian origin, preferably of human origin, depending on which animal shall be treated. A human subject, for example, is preferably treated by a therapeutic protein of human origin. 
     Pathogenic adjuvant proteins, typically comprise a pathogenic adjuvant protein, which is capable of eliciting an innate immune response (in a mammal), more preferably selected from pathogenic adjuvant proteins derived from bacteria, protozoa, viruses, or fungi, etc., e.g., bacterial (adjuvant) proteins, protozoan (adjuvant) proteins (e.g. profilin-like protein of  Toxoplasma gondii ), viral (adjuvant) proteins, or fungal (adjuvant) proteins, etc. 
     Particularly, bacterial (adjuvant) proteins may be selected from the group consisting of bacterial heat shock proteins or chaperons, including Hsp60, Hsp70, Hsp90, Hsp100; OmpA (Outer membrane protein) from gram-negative bacteria; bacterial porins, including OmpF; bacterial toxins, including pertussis toxin (PT) from  Bordetella pertussis , pertussis adenylate cyclase toxin CyaA and CyaC from  Bordetella pertussis , PT-9K/129G mutant from pertussis toxin, pertussis adenylate cyclase toxin CyaA and CyaC from  Bordetella pertussis , tetanus toxin, cholera toxin (CT), cholera toxin B-subunit, CTK63 mutant from cholera toxin, CTE112K mutant from CT,  Escherichia coli  heat-labile enterotoxin (LT), B subunit from heat-labile enterotoxin (LTB)  Escherichia coli  heat-labile enterotoxin mutants with reduced toxicity, including LTK63, LTR72; phenol-soluble modulin; neutrophil-activating protein (HP-NAP) from  Helicobacter pylori ; Surfactant protein D; Outer surface protein A lipoprotein from  Borrelia burgdorferi , Ag38 (38 kDa antigen) from  Mycobacterium tuberculosis ; proteins from bacterial fimbriae; Enterotoxin CT of  Vibrio cholerae , Pilin from pili from gram negative bacteria, and Surfactant protein A; etc., or any species homolog of any of the above bacterial (adjuvant) proteins. 
     Bacterial (adjuvant) proteins may also comprise bacterial flagellins. In the context of the present invention, bacterial flagellins may be selected from flagellins from organisms including, without being limited thereto,  Agrobacterium, Aquifex, Azospirillum, Bacillus, Bartonella, Bordetella, Borrelia, Burkholderia, Campylobacter, Caulobacte, Clostridium, Escherichia, Helicobacter, Lachnospiraceae, Legionella, Listeria, Proteus, Pseudomonas, Rhizobium, Rhodobacter, Roseburia, Salmonella, Serpulina, Serratia, Shigella, Treponema, Vibrio, Wolinella, Yersinia , more preferably from flagellins from the species including, without being limited thereto,  Agrobacterium tumefaciens, Aquifex pyrophilus, Azospirillum brasilense, Bacillus subtilis, Bacillus thuringiensis, Bartonella bacilliformis, Bordetella bronchiseptica, Borrelia burgdorferi, Burkholderia cepacia, Campylobacter jejuni, Caulobacter crescentus, Clostridium botulinum  strain Bennett clone 1,  Escherichia coli, Helicobacter pylori, Lachnospiraceae bacterium, Legionella pneumophila, Listeria monocytogenes, Proteus mirabilis, Pseudomonas aeroguinosa, Pseudomonas syringae, Rhizobium meliloti, Rhodobacter sphaeroides, Roseburia cecicola, Roseburis hominis, Salmonella typhimurium, Salmonella bongori, Salmonella typhi, Salmonella enteritidis, Serpulina hyodysenteriae, Serratia marcescens, Shigella boydii, Treponema phagedenis, Vibrio alginolyticus, Vibrio cholerae, Vibrio parahaemolyticus, Wolinella succinogenes  and  Yersinia enterocolitica.    
     Protozoan (adjuvant) proteins are a further example of pathogenic adjuvant proteins. Protozoan (adjuvant) proteins may be selected in this context from any protozoan protein showing adjuvant properties, more preferably, from the group consisting of, without being limited thereto, Tc52 from  Trypanosoma cruzi , PFTG from  Trypanosoma gondii , Protozoan heat shock proteins, LeIF from  Leishmania  spp., profiling-like protein from  Toxoplasma gondii , etc. 
     Viral (adjuvant) proteins are another example of pathogenic adjuvant proteins. In this context, viral (adjuvant) proteins may be selected from any viral protein showing adjuvant properties, more preferably, from the group consisting of, without being limited thereto, Respiratory Syncytial Virus fusion glycoprotein (F-protein), envelope protein from MMT virus, mouse leukemia virus protein, Hemagglutinin protein of wild-type measles virus, etc. 
     Fungal (adjuvant) proteins are even a further example of pathogenic adjuvant proteins. In the context of the present invention, fungal (adjuvant) proteins may be selected from any fungal protein showing adjuvant properties, more preferably, from the group consisting of, fungal immunomodulatory protein (FIP; LZ-8), etc. 
     Finally, adjuvant proteins may furthermore be selected from the group consisting of, Keyhole limpet hemocyanin (KLH), OspA, etc. 
     As mentioned above, also therapeutic antibodies are defined herein as therapeutic proteins. These therapeutic antibodies are preferably selected from antibodies, which are used inter alia for the treatment of cancer or tumor diseases, e.g. 131I-tositumomab (Follicular lymphoma, B cell lymphomas, leukemias), 3F8 (Neuroblastoma), 8H9, Abagovomab (Ovarian cancer), Adecatumumab (Prostate and breast cancer), Afutuzumab (Lymphoma), Alacizumab pegol, Alemtuzumab (B-cell chronic lymphocytic leukaemia, T-cell-Lymphoma), Amatuximab, AME-133v (Follicular lymphoma, cancer), AMG 102 (Advanced Renal Cell Carcinoma), Anatumomab mafenatox (Non-small cell lung carcinoma), Apolizumab (Solid Tumors, Leukemia, Non-Hodgkin-Lymphoma, Lymphoma), Bavituximab (Cancer, viral infections), Bectumomab (Non-Hodgkin&#39;s lymphoma), Belimumab (Non-Hodgkin lymphoma), Bevacizumab (Colon Cancer, Breast Cancer, Brain and Central Nervous System Tumors, Lung Cancer, Hepatocellular Carcinoma, Kidney Cancer, Breast Cancer, Pancreatic Cancer, Bladder Cancer, Sarcoma, Melanoma, Esophageal Cancer; Stomach Cancer, Metastatic Renal Cell Carcinoma; Kidney Cancer, Glioblastoma, Liver Cancer, Proliferative Diabetic Retinopathy, Macular Degeneration), Bivatuzumab mertansine (Squamous cell carcinoma), Blinatumomab, Brentuximab vedotin (Hematologic cancers), Cantuzumab (Colon Cancer, Gastric Cancer, Pancreatic Cancer, NSCLC), Cantuzumab mertansine (Colorectal cancer), Cantuzumab ravtansine (Cancers), Capromab pendetide (Prostate cancer), Carlumab, Catumaxomab (Ovarian Cancer, Fallopian Tube Neoplasms, Peritoneal Neoplasms), Cetuximab (Metastatic colorectal cancer and head and neck cancer), Citatuzumab bogatox (Ovarian cancer and other solid tumors), Cixutumumab (Solid tumors), Clivatuzumab tetraxetan (Pancreatic cancer), CNTO 328 (B-Cell Non-Hodgkin&#39;s Lymphoma, Multiple Myeloma, Castleman&#39;s Disease, ovarian cancer), CNTO 95 (Melanoma), Conatumumab, Dacetuzumab (Hematologic cancers), Dalotuzumab, Denosumab (Myeloma, Giant Cell Tumor of Bone, Breast Cancer, Prostate Cancer, Osteoporosis), Detumomab (Lymphoma), Drozitumab, Ecromeximab (Malignant melanoma), Edrecolomab (Colorectal carcinoma), Elotuzumab (Multiple myeloma), Elsilimomab, Enavatuzumab, Ensituximab, Epratuzumab (Autoimmune diseases, Systemic Lupus Erythematosus, Non-Hodgkin-Lymphoma, Leukemia), Ertumaxomab (Breast cancer), Ertumaxomab (Breast Cancer), Etaracizumab (Melanoma, prostate cancer, ovarian cancer), Farletuzumab (Ovarian cancer), FBTA05 (Chronic lymphocytic leukaemia), Ficlatuzumab (Cancer), Figitumumab (Adrenocortical carcinoma, non-small cell lung carcinoma), Flanvotumab (Melanoma), Galiximab (B-cell lymphoma), Galiximab (Non-Hodgkin-Lymphoma), Ganitumab, GC1008 (Advanced Renal Cell Carcinoma; Malignant Melanoma, Pulmonary Fibrosis), Gemtuzumab (Leukemia), Gemtuzumab ozogamicin (Acute myelogenous leukemia), Girentuximab (Clear cell renal cell carcinoma), Glembatumumab vedotin (Melanoma, breast cancer), GS6624 (Idiopathic pulmonary fibrosis and solid tumors), HuC242-DM4 (Colon Cancer, Gastric Cancer, Pancreatic Cancer), HuHMFG1 (Breast Cancer), HuN901-DM1 (Myeloma), Ibritumomab (Relapsed or refractory low-grade, follicular, or transformed B-cell non-Hodgkin&#39;s lymphoma (NHL)), Icrucumab, ID09C3 (Non-Hodgkin-Lymphoma), Indatuximab ravtansine, Inotuzumab ozogamicin, Intetumumab (Solid tumors (Prostate cancer, melanoma)), Ipilimumab (Sarcoma, Melanoma, Lung cancer, Ovarian Cancer leucemia, Lymphoma, Brain and Central Nervous System Tumors, Testicular Cancer, Prostate Cancer, Pancreatic Cancer, Breast Cancer), Iratumumab (Hodgkin&#39;s lymphoma), Labetuzumab (Colorectal cancer), Lexatumumab, Lintuzumab, Lorvotuzumab mertansine, Lucatumumab (Multiple myeloma, non-Hodgkin&#39;s lymphoma, Hodgkin&#39;s lymphoma), Lumiliximab (Chronic lymphocytic leukemia), Mapatumumab (Colon Cancer, Myeloma), Matuzumab (Lung Cancer, Cervical Cancer, Esophageal Cancer), MDX-060 (Hodgkin-Lymphoma, Lymphoma), MEDI 522 (Solid Tumors, Leukemia, Lymphoma, Small Intestine Cancer, Melanoma), Mitumomab (Small cell lung carcinoma), Mogamulizumab, MORab-003 (Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer), MORab-009 (Pancreatic Cancer, Mesothelioma, Ovarian Cancer, Non-Small Cell Lung Cancer, Fallopian Tube Cancer, Peritoneal Cavity Cancer), Moxetumomab pasudotox, MT103 (Non-Hodgkin-Lymphoma), Nacolomab tafenatox (Colorectal cancer), Naptumomab estafenatox (Non-small cell lung carcinoma, renal cell carcinoma), Narnatumab, Necitumumab (Non-small cell lung carcinoma), Nimotuzumab (Squamous cell carcinoma, head and neck cancer, nasopharyngeal cancer, glioma), Nimotuzumab (Squamous cell carcinomas, Glioma, Solid Tumors, Lung Cancer), Olaratumab, Onartuzumab (Cancer), Oportuzumab monatox, Oregovomab (Ovarian cancer), Oregovomab (Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cavity Cancer), PAM4 (Pancreatic Cancer), Panitumumab (Colon Cancer, Lung Cancer, Breast Cancer; Bladder Cancer; Ovarian Cancer), Patritumab, Pemtumomab, Pertuzumab (Breast Cancer, Ovarian Cancer, Lung Cancer, Prostate Cancer), Pritumumab (Brain cancer), Racotumomab, Radretumab, Ramucirumab (Solid tumors), Rilotumumab (Solid tumors), Rituximab (Urticaria, Rheumatoid Arthritis, Ulcerative Colitis, Chronic Focal Encephalitis, Non-Hodgkin-Lymphoma, Lymphoma, Chronic Lymphocytic Leukemia), Robatumumab, Samalizumab, SGN-30 (Hodgkin-Lymphoma, Lymphoma), SGN-40 (Non-Hodgkin-Lymphoma, Myeloma, Leukemia, Chronic Lymphocytic Leukemia), Sibrotuzumab, Siltuximab, Tabalumab (B-cell cancers), Tacatuzumab tetraxetan, Taplitumomab paptox, Tenatumomab, Teprotumumab (Hematologic tumors), TGN1412 (Chronic lymphocytic leukemia, rheumatoid arthritis), Ticilimumab (=tremelimumab), Tigatuzumab, TNX-650 (Hodgkin&#39;s lymphoma), Tositumomab (Follicular lymphoma, B cell lymphomas, Leukemias, Myeloma), Trastuzumab (Breast Cancer, Endometrial Cancer, Solid Tumors), TRBS07 (Melanoma), Tremelimumab, TRU-016 (Chronic lymphocytic leukemia), TRU-016 (Non-Hodgkin lymphoma), Tucotuzumab celmoleukin, Ublituximab, Urelumab, Veltuzumab (Non-Hodgkin&#39;s lymphoma), Veltuzumab (IMMU-106) (Non-Hodgkin&#39;s lymphoma), Volociximab (Renal Cell Carcinoma, Pancreatic Cancer, Melanoma), Votumumab (Colorectal tumors), WX-G250 (Renal Cell Carcinoma), Zalutumumab (Head and Neck Cancer, Squamous Cell Cancer), and Zanolimumab (T-Cell-Lymphoma); 
     Epitope: Epitopes (also called ‘antigen determinant’) can be distinguished in T cell epitopes and B cell epitopes. T cell epitopes or parts of the proteins in the context of the present invention may comprise fragments preferably having a length of about 6 to about 20 or even more amino acids, e.g. fragments as processed and presented by MHC class I molecules, preferably having a length of about 8 to about 10 amino acids, e.g. 8, 9, or 10, (or even 11, or 12 amino acids), or fragments as processed and presented by MHC class II molecules, preferably having a length of about 13 or more amino acids, e.g. 13, 14, 15, 16, 17, 18, 19, 20 or even more amino acids, wherein these fragments may be selected from any part of the amino acid sequence. These fragments are typically recognized by T cells in form of a complex consisting of the peptide fragment and an MHC molecule, i.e. the fragments are typically not recognized in their native form. B cell epitopes are typically fragments located on the outer surface of (native) protein or peptide antigens as defined herein, preferably having 5 to 15 amino acids, more preferably having 5 to 12 amino acids, even more preferably having 6 to 9 amino acids, which may be recognized by antibodies, i.e. in their native form. 
     Such epitopes of proteins or peptides may furthermore be selected from any of the herein mentioned variants of such proteins or peptides. In this context, antigenic determinants can be conformational or discontinuous epitopes, which are composed of segments of the proteins or peptides as defined herein that are discontinuous in the amino acid sequence of the proteins or peptides as defined herein, but are brought together in the three-dimensional structure or continuous or linear epitopes, which are composed of a single polypeptide chain. 
     Northern Blot: The northern blot is a technique used in molecular biology research to study gene expression by detection of RNA (or isolated mRNA) in a sample. Northern blotting involves the use of electrophoresis to separate RNA samples by size, and detection with a hybridization probe complementary to part of or the entire target sequence. The term ‘northern blot’ actually refers specifically to the capillary transfer of RNA from the electrophoresis gel to the blotting membrane. A general blotting procedure starts with extraction of total RNA from a sample or from cells. Eukaryotic mRNA can then be isolated through the use of oligo (dT) cellulose chromatography to isolate only those RNAs with a poly(A) tail. RNA samples are then separated by gel electrophoresis. Since the gels are fragile and the probes are unable to enter the matrix, the RNA samples, now separated by size, are transferred to a nylon membrane through a capillary or vacuum blotting system. A nylon membrane with a positive charge is the most effective for use in northern blotting since the negatively charged nucleic acids have a high affinity for them. The transfer buffer used for the blotting usually contains formamide because it lowers the annealing temperature of the probe-RNA interaction, thus eliminating the need for high temperatures, which could cause RNA degradation. Once the RNA has been transferred to the membrane, it is immobilized through covalent linkage to the membrane by UV light or heat. After a probe has been labeled, it is hybridized to the RNA on the membrane. The membrane is washed to ensure that the probe has bound specifically and to prevent background signals from arising. The hybrid signals are then detected by X-ray film and can be quantified by densitometry. The RNA samples are most commonly separated on agarose gels containing formaldehyde as a denaturing agent for the RNA to limit secondary structure. The gels can be stained with ethidium bromide (EtBr) and viewed under UV light to observe the quality and quantity of RNA before blotting. Polyacrylamide gel electrophoeresis with urea can also be used in RNA separation but it is most commonly used for fragmented RNA or microRNAs. Probes for northern blotting are composed of nucleic acids with a complementary sequence to all or part of the RNA of interest, they can be DNA, RNA, or oligonucleotides with a minimum of 25 complementary bases to the target sequence. RNA probes (riboprobes) that are transcribed in vitro are able to withstand more rigorous washing steps preventing some of the background noise. Commonly cDNA is created with labelled primers for the RNA sequence of interest to act as the probe in the northern blot. The probes must be labelled either with radioactive isotopes (32P) or with chemiluminescence in which alkaline phosphatase or horseradish peroxidase (HRP) break down chemiluminescent substrates producing a detectable emission of light. The chemiluminescent labelling can occur in two ways: either the probe is attached to the enzyme, or the probe is labelled with a ligand (e.g. biotin) for which the ligand (e.g., avidin or streptavidin) is attached to the enzyme (e.g. HRP). X-ray film can detect both the radioactive and chemiluminescent signals. 
     RNA Sequencing: RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing, uses next-generation sequencing (NGS) to reveal the presence and quantity of RNA in a biological sample at a given moment in time. The high demand for low-cost sequencing has driven the development of high-throughput sequencing (or next-generation sequencing) technologies that parallelize the sequencing process, producing thousands or millions of sequences concurrently. In order to sequence RNA, the usual method is first to reverse transcribe the sample to generate cDNA fragments. 
     Reverse Transcriptase: A Reverse transcriptase (RT) is an enzyme used to generate complementary DNA (cDNA) from an RNA template, a process termed reverse transcription. 
     It is mainly associated with retroviruses. Retroviral RT has three sequential biochemical activities: RNA-dependent DNA polymerase activity, ribonuclease H, and DNA-dependent DNA polymerase activity. 
     Reverse Transcription: Reverse transcription is the process of generating a complementary DNA form an RNA template by a reverse transcriptase. 
     RT-PCR (Reverse transcription polymerase chain reaction): In RT-PCR, the RNA template is first converted into a complementary DNA (cDNA) using a reverse transcriptase. The cDNA is then used as a template for exponential amplification using PCR. 
     Quantitative Polymerase chain reaction (qPCR) or real-time polymerase chain reaction: A real-time polymerase chain reaction is a laboratory technique of molecular biology based on the polymerase chain reaction (PCR), which is used to amplify and simultaneously detect or quantify a targeted DNA molecule. The procedure follows the general principle of polymerase chain reaction (PCR); its key feature is that the amplified DNA is detected as the reaction progresses in “real time”. Two common methods for the detection of products in quantitative PCR are: (1) non-specific fluorescent dyes that intercalate with any double-stranded DNA, and (2) sequence-specific DNA probes consisting of oligonucleotides that are labelled with a fluorescent reporter, which permits detection only after hybridization of the probe with its complementary sequence to quantify nucleic acids. Quantitative PCR is carried out in a thermal cycler with the capacity to illuminate each sample with a beam of light of a specified wavelength and detect the fluorescence emitted by the excited fluorophore. The thermal cycler is also able to rapidly heat and chill samples, thereby taking advantage of the physicochemical properties of the nucleic acids and DNA polymerase. The PCR process generally consists of a series of temperature changes that are repeated 25-40 times. These cycles normally consist of three stages: the first, at around 95° C., allows the separation of the nucleic acid&#39;s double chain; the second, at a temperature of around 50-60° C., allows the binding of the primers with the DNA template; the third, at between 68-72° C., facilitates the polymerization carried out by the DNA polymerase. Due to the small size of the fragments the last step is usually omitted in this type of PCR as the enzyme is able to increase their number during the change between the alignment stage and the denaturing stage. In addition, some thermal cyclers add another short temperature phase lasting only a few seconds to each cycle, with a temperature of, for example, 80° C., in order to reduce the noise caused by the presence of primer dimers when a non-specific dye is used. The temperatures and the timings used for each cycle depend on a wide variety of parameters, such as: the enzyme used to synthesize the DNA, the concentration of divalent ions and deoxyribonucleotides (dNTPs) in the reaction and the bonding temperature of the primers. The type of quantitative PCR technique used depends on the DNA sequence in the samples, the technique can either use non-specific fluorochromes or hybridization probes. 
     DETAILED DESCRIPTION OF THE INVENTION 
     The present invention relates to a method of diagnosing, monitoring a subject or determining the prognosis of a subject comprising the steps of (a) determining the expression level of at least one marker gene selected from the group consisting of the genes set out in table 1 in a sample of the subject to obtain a gene expression profile; (b) diagnosing, monitoring a subject or determining the prognosis of the subject based on the gene expression profile obtained in step (a). 
     In particular, the invention relates to a method of determining the prognosis of a patient comprising the steps of (a) determining the expression level of at least one marker gene selected from the group consisting of the marker genes set out in table 1 in a sample of the patient to obtain a gene expression profile; (b) determining the prognosis of the patient based on the gene expression profile obtained in step (a). 
     The patient may be a patient suffering from cancer or tumor. In preferred embodiments, the patient is a lung cancer patient. Most preferably the patient is a non-small cell lung cancer (NSCLC) patient. 
     Therefore, the invention in particular relates to a method of determining the prognosis of a cancer or tumor patient comprising the steps of (a) determining the expression level of at least one marker gene selected from the group consisting of the marker genes set out in table 1 in a sample of the cancer patient to obtain a gene expression profile; (b) determining the prognosis of the cancer patient based on the gene expression profile obtained in step (a). 
     In preferred embodiments, the invention relates to a method of determining the prognosis of a NSCLC patient comprising the steps of (a) determining the expression level of at least one marker gene selected from the group consisting of the marker genes set out in table 1 in a sample of the NSCLC cancer patient to obtain a gene expression profile; (b) determining the prognosis of the NSCLC cancer patient based on the gene expression profile obtained in step (a). 
     The expression level may be determined for at least one marker gene, at least 2 marker genes, at least 3 marker genes, at least 4 marker genes, at least 5 marker genes, at least 6 marker genes, at least 7 marker genes, at least 8 marker genes, at least 9 marker genes, at least 10 marker genes, at least 11 marker genes, at least 12 marker genes, at least 13 marker genes, at least 14 marker genes, at least 15 marker genes, at least 16 marker genes, at least 17 marker genes, at least 18 marker genes, at least 19 marker genes, at least 20 marker genes, at least 25 marker genes, at least 30 marker genes, at least 35 marker genes, at least 40 marker genes, at least 45 marker genes, at least 50 marker genes, at least 55 marker genes, at least 60 marker genes, at least 70 marker genes, at least 80 marker genes, at least 90 marker genes at least 100 marker genes. 
     The expression level may be determined for at least one marker gene, preferably at least 15 marker genes, more preferably at least 20 marker genes, even more preferably at least 30 marker genes, still more preferably at least 50 marker genes, most preferably at least 100 marker genes. 
     The expression level may be determined for example for one marker gene, 2 marker genes, 3 marker genes, 4 marker genes, 5 marker genes, 6 marker genes, 7 marker genes, 8 marker genes, 9 marker genes, 10 marker genes, 11 marker genes, 12 marker genes, 13 marker genes, 14 marker genes, 15 marker genes, 16 marker genes, 17 marker genes, 18 marker genes, 19 marker genes, 20 marker genes, 25 marker genes, 30 marker genes, 35 marker genes, 40 marker genes, 45 marker genes, 50 marker genes, 55 marker genes, 60 marker genes, 70 marker genes, 80 marker genes, 90 marker genes or 100 marker genes. 
     In specific embodiments, the at least one marker gene is selected from the group consisting of genes set out in table 2. In preferred embodiments, the at least one marker gene is selected from the group consisting of marker genes set out in table 3. In more preferred embodiments, the at least one marker gene is selected from group consisting of marker genes set out in table 4. In even more preferred embodiments, the at least one marker gene is selected from group consisting of marker genes set out in table 5. 
     In some embodiments at least 10 marker genes, such as 15, 25 or 25 marker genes, are selected from table 1. Preferably at least 30 marker genes, such as 35, 40 or 45 marker genes, more preferably at least 50 marker genes, such as 55, 60, 65, 70, 75, 80, 85, 90 or 95 marker genes, most preferably at least 100 marker genes are selected from table 1. 
     In some embodiments at least 10 marker genes, such as 15, 25 or 25 marker genes, are selected from table 2. Preferably at least 30 marker genes, such as 35, 40 or 45 marker genes, more preferably at least 50 marker genes, such as 55, 60, 65, 70, 75, 80, 85, 90 or 95 marker genes, most preferably at least 100 marker genes are selected from table 2. 
     In some embodiments at least 10 genes, such as 15, 25 or 25 marker genes, are selected from table 3. Preferably at least 30 marker genes, such as 35, 40 or 45 marker genes, more preferably at least 50 marker genes are selected from table 3. 
     In some embodiments at least 10 genes, such as 15 marker genes, are selected from table 4. Preferably at least 20 marker genes, such as 25 marker genes, more preferably at least 30 marker genes are selected from table 4. 
     In some embodiments at least 10 marker genes, such as 15 marker genes are selected from table 5. 
     The expression level of the at least one marker gene may be determined by any means known in the art. In a preferred embodiment of the present invention the determination of the expression level of the marker gene is accomplished by the measurement of nucleic acid. Thus, the expression level(s) may be determined by a method involving the detection of an mRNA encoded by the gene. Such methods include e.g. Nothem Blot analysis, (quantitative or semi-quantitative) RT-PCR, microarray analysis, and RNA sequencing (“next generation sequencing”). 
     For example, the measurement of the nucleic acid level of marker gene(s) expression may be assessed by purification of nucleic acid molecules (e.g. RNA) obtained from the sample, followed by hybridization with specific nucleic acid based probes selective for determining the expression level of the marker genes as defined herein. Comparison of expression levels may be accomplished visually or by means of an appropriate device. Methods for the detection of mRNA or expression products are known to the person skilled in the art. 
     Alternatively, the nucleic acid level of marker gene(s) expression may be detected in a microarray approach. Typically, sample nucleic acids derived from patients to be tested are processed and labeled, preferably with a fluorescent label. Subsequently, such nucleic acid molecules may be used in a hybridization approach with immobilized capture probes corresponding to the marker genes of the present invention. Suitable means for carrying out microarray analyses are known to the person skilled in the art. In a standard setup a microarray comprises immobilized high-density probes to detect a number of genes. The probes on the array are complementary to one or more parts of the mRNA sequence of the marker genes. 
     A microarray-based detection method typically comprises the following steps: (1) Isolating mRNA from a sample and optionally converting the mRNA to cDNA by reverse transcription, and subsequently labeling this RNA or cDNA. Methods for isolating RNA, converting it into cDNA by reverse transcription and for labeling nucleic acids are described in manuals for microarray technology. (2) Hybridizing the nucleic acids from step 1 with probes for the marker genes. The nucleic acids from a sample can be labeled with a dye, such as the fluorescent dyes Cy3 (red) or Cy5 (blue). Generally, a control sample is labeled with a different dye. (3) Detecting the hybridization of the nucleic acids from the sample with the probes and determining at least qualitatively, and more particularly quantitatively, the amounts of mRNA in the sample for marker genes investigated. The difference in the expression level between sample and control can be estimated based on a difference in the signal intensity. These can be measured and analyzed by appropriate software. 
     There is no limitation on the number of probes corresponding to the marker genes used, which are spotted on a microarray. Also, a marker gene can be represented by two or more probes, the probes hybridizing to different parts of a gene. Probes are designed for each selected marker gene. Such a probe is typically an oligonucleotide comprising 5-50 nucleotide residues. Longer DNAs can be synthesized by PCR or chemically. Methods for synthesizing such oligonucleotides and applying them on a substrate are well known in the field of microarrays. Genes other than the marker genes may be also spotted on the DNA array. For example, a probe for a gene whose expression level is not significantly altered may be spotted on the DNA array to normalize assay results or to compare assay results of multiple arrays or different assays. Such a gene is also termed herein as “reference gene”. 
     Alternatively, the nucleic acid level of marker gene(s) expression may be detected in a quantitative RT-PCR approach, preferably in a real-time PCR approach following the reverse transcription of the transcripts of interest. Typically, as first step, a transcript is reverse transcribed into a cDNA molecule according to any suitable method known to the person skilled in the art. A quantitative or real-time PCR approach may subsequently be carried out based on a first DNA strand obtained as described above. 
     Preferably, Taqman or Molecular Beacon probes as principal FRET-based probes of this type may be used for quantitative PCR detection. In both cases, the probes, serve as internal probes which are used in conjunction with a pair of opposing primers that flank the target region of interest, preferably a set of marker gene(s) specific oligonucleotides as defined herein above. Upon amplification of a target segment, the probe may selectively bind to the products at an identifying sequence in between the primer sites, thereby causing increases in FRET signaling relative to increases in target frequency. 
     Preferably, a Taqman probe to be used for a quantitative PCR approach according to the present invention may comprises a specific oligonucleotide as defined above of about 22 to 30 bases that is labeled on both ends with a FRET pair. Typically, the 5′ end will have a shorter wavelength fluorophore such as fluorescein (e.g. FAM) and the 3′ end is commonly labeled with a longer wavelength fluorescent quencher (e.g. TAMRA) or a non-fluorescent quencher compound (e.g. Black Hole Quencher). It is preferred that the probes to be used for quantitative PCR, in particular probes as defined herein above, have no guanine (G) at the 5′ end adjacent to the reporter dye in order to avoid quenching of the reporter fluorescence after the probe is degraded. 
     A Molecular Beacon probe to be used for a quantitative PCR approach according to the present invention preferably uses FRET interactions to detect and quantify a PCR product, with each probe having a 5′ fluorescent-labeled end and a 3′ quencher-labeled end. This hairpin or stem-loop configuration of the probe structure comprises preferably a stem with two short self-binding ends and a loop with a long internal target-specific region of about 20 to 30 bases. 
     Alternative detection mechanisms which may also be employed in the context of the present invention are directed to a probe fabricated with only a loop structure and without a short complementary stem region. An alternative FRET-based approach for quantitative PCR which may also be used in the context of the present invention is based on the use of two hybridization probes that bind to adjacent sites on the target wherein the first probe has a fluorescent donor label at the 3′ end and the second probe has a fluorescent acceptor label at its 5′ end. 
     Also detection techniques using molecular barcodes, for example color coded molecular barcodes (such as nCounter from Nanostring technologies) may be used. Typically, in such methods a reporter probe carrying the signal and a capture probe are used. After hybridization, the excess probes are removed and the complexes containing the target sequence hybridized to the signal probe and the capture probe are aligned, immobilized in a cartridge and the color codes of the signal probe are counted. 
     Alternatively, the nucleic acid level of marker gene(s) expression may be detected by RNA sequencing. RNA sequencing, also called whole transcriptome shotgun sequencing (WTSS), uses next-generation sequencing (NGS) to reveal the presence and quantity of RNA in a biological sample at a given moment in time. Different methods used for next-generation sequencing are known in the art. 
     In specific embodiments the expression level is measured before administration and/or after administration of a least one dose of a therapeutic agent. 
     In preferred embodiments the gene expression profile of step (a) is obtained by determining the difference of the expression level of the at least one marker gene measured before administration of the therapeutic agent and after the administration of at least one dose of the therapeutic agent. 
     Therefore, some embodiments of the invention relate to a method of determining the prognosis of a patient comprising the steps of (a) determining the difference of the expression level of the at least one marker gene before administration of the therapeutic agent and after the administration of at least one dose of the therapeutic agent in sample of the patient to obtain a gene expression profile; (b) determining the prognosis of the patient based on the gene expression profile obtained in step (a). 
     In particular, some embodiments of the present invention relate to a method of determining the prognosis of a cancer patient, preferably a lung cancer patient, and most preferably a NSCLC patient, comprising the steps of (a) determining the difference of the expression level of the at least one marker gene before administration of the therapeutic agent and after the administration of at least one dose of the therapeutic agent in sample of the cancer patient to obtain a gene expression profile; (b) determining the prognosis of the cancer patient based on the gene expression profile obtained in step (a). 
     In this context therapeutic agents include all agents and therapies used for therapy or prevention of a disease, particularly of tumor or cancer diseases. Particularly preferred are surgery, radiation therapy, chemotherapy, chemoradiation, and/or treatment with kinase inhibitors, inhibitory and/or stimulatory checkpoint molecules (checkpoint modulators) or antibodies. Most preferably therapeutic agents are selected from vaccines and/or immunostimulatory compositions and/or immunotherapeutic agents, preferably as defined herein. 
     In one embodiment it is particularly preferred that the vaccine or immunostimulatory composition comprises at least one antigen, preferably a tumor antigen as defined herein. 
     A specific embodiment of the invention relates to a method of determining the prognosis of a cancer patient, preferably a lung cancer patient and more preferably a NSCLC patient comprising the steps of (a) determining the difference of the expression level of the at least one marker gene before administration of a vaccine or immunostimulatory composition comprising at least one tumor antigen of the group consisting of MAGE-C1, MAGE-C2, NY-ESO-1, Survivin and 5T4 and after the administration of at least one dose of said vaccine or immunotherapeutic agent in a sample of the cancer patient to obtain a gene expression profile; (b) determining the prognosis of the cancer patient based on the gene expression profile obtained in step (a). 
     A specific embodiment of the invention relates to a method of determining the prognosis of a cancer patient, preferably a lung cancer patient and more preferably a NSCLC patient comprising the steps of (a) determining the difference of the expression level of the at least one marker gene before administration of a vaccine or immunostimulatory composition comprising the tumor antigens MAGE-C1, MAGE-C2, NY-ESO-1, Survivin and 5T4 and after the administration of at least one dose of said vaccine or immunostimulatory composition in a sample of the cancer patient to obtain a gene expression profile; (b) determining the prognosis of the cancer patient based on the gene expression profile obtained in step (a). 
     Another specific embodiment of the invention relates to a method of determining the prognosis of a cancer patient, preferably a lung cancer patient, more preferably a NSCLC patient comprising the steps of (a) determining the difference of the expression level of the at least one marker gene before administration of a vaccine or immunostimulatory composition comprising the antigens MAGE-C1, MAGE-C2, NY-ESO-1, Survivin, 5T4, and Muc-1 and after the administration of at least one dose of said vaccine or immunotherapeutic agent in a sample of the NSCLC patient to obtain a gene expression profile; (b) determining the prognosis of the cancer patient based on the gene expression profile obtained in step (a). 
     The sample of the individual or patient can be any sample suitable for the analysis of the expression of the marker genes as disclosed herein. The sample of the individual or patient may be without limitation whole blood or fractions thereof, such as peripheral blood mono-nuclear cells (PBMCs). Preferably, the sample of the individual or patient comprises PBMCs. Alternatively, the sample may be any tissue of the patient, preferably tumor tissue. 
     In step (b) the prognosis of a cancer patient may be obtained based on the gene expression profile obtained in step (a). For example, the increase or decrease of the expression of the at least one marker gene may relate to a certain course or outcome of a diagnosed or detected disease. For example, the increase or decrease of the expression of the at least one marker gene may relate to a chance of survival or recovery from the disease, to an expected survival time of a subject. For example, the increase or decrease of the expression of the at least one marker gene as described herein may indicate the expected survival time of a subject. In particular, if the prognosis in step (b) is determined based on an expression profile of several genes, for example 30, 50 or 100 or more genes, algorithms can be used to determine the prognosis of a cancer patient. Preferably, clustering algorithms, more preferably hierarchical clustering algorithms can be used in step (b). 
     Typically, the therapeutic agent may be an immunostimulatory composition and/or a vaccine and/or an immunotherapeutic agent. The therapeutic agent may be a therapeutic protein as defined above or may comprise additionally a therapeutic protein. Preferably the therapeutic agent comprises the antigens MAGE-C1, MAGE-C2, NY-ESO-1, Survivin and 5T4 or fragments thereof. The antigen(s) may be present as peptides or proteins and/or are encoded by at least one nucleotide sequence. Preferably the antigens are encoded by at least one mRNA molecule. In a specific embodiment the therapeutic agent is at least one mRNA molecule encoding the antigens MAGE-C1, MAGE-C2, NY-ESO-1, Survivin and 5T4 or fragments thereof. 
     In the context of this invention “MAGE-C1” is the melanoma antigen family C, 1 and the preferred sequence of the RNA, preferably of the mRNA, encoding “MAGE-C1”—if being used in the immunostimulatory composition—is shown in SEQ ID NO: 1, more preferably in SEQ ID NO: 2, and even more preferably in SEQ ID NO: 3. 
     In the context of this invention “MAGE-C2” is the melanoma antigen family C2 and the preferred sequence of the RNA, preferably of the mRNA, encoding “MAGE-C2”—if being used in the immunostimulatory composition—is shown in SEQ ID NO: 4, and even more preferably SEQ ID NO: 5. 
     In the context of this invention “NY-ESO-1” is cancer/testis antigen 1B and the preferred sequence of the RNA, preferably of the mRNA, encoding “NY-ESO-1”—if being used in the immunostimulatory composition—is shown in SEQ ID NO: 6, and in SEQ ID NO: 7. 
     In the context of this invention “Survivin” is baculoviral IAP repeat-containing 5 (survivin) and the preferred sequence of the RNA, preferably of the mRNA, encoding “survivin”—if being used in the immunostimulatory composition—is shown in SEQ ID NO: 8, and even more preferably in SEQ ID NO: 9. 
     In the context of this invention “5T4” is trophoblast glycoprotein and the preferred sequence of the RNA, preferably of the mRNA, encoding “5T4”—if being used in the vaccine—is shown in SEQ ID NO: 10, and even more preferably in SEQ ID NO: 11. 
     The immunostimulatory composition may comprise antigens, antigenic proteins or antigenic peptides or nucleic acids such as DNA or RNA encoding antigens, antigenic proteins or antigenic peptides capable to effectively stimulate the (adaptive) immune system to allow treatment of cancer, preferably lung cancer, especially of non-small cell lung cancer (NSCLC). Preferably the immunostimulatory composition comprises at least one RNA encoding at least one antigen, antigenic protein or antigenic peptide. 
     Preferably, the immunostimulatory composition or vaccine comprises at least one RNA encoding at least one antigen selected from the group consisting of MAGE-C1, MAGE-C2, NY-ESO-1, Survivin and 5T4, wherein the at least one RNA is complexed to a complexing agent, preferably protamine. 
     The vaccine may contain the active immunostimulatory composition. The vaccine may additionally contain a pharmaceutically acceptable carrier and/or further auxiliary substances and additives and/or adjuvants. According to a particularly preferred embodiment, the antigens are selected from the group consisting of MAGE-C1, MAGE-C2, NY-ESO-1, Survivin and 5T4. 
     According to another embodiment, the antigens are selected from the group consisting of
         STEAP (Six Transmembrane Epithelial Antigen of the Prostate);   PSA (Prostate-Specific Antigen),   PSMA (Prostate-Specific Membrane Antigen),   PSCA (Prostate Stem Cell Antigen);   PAP (Prostatic Acid Phosphatase), and   MUC1 (Mucin 1).       

     The antigens are described in detail in WO2015024664, which is incorporated herein by reference. Also the multi-antigenic CV9104 is an mRNA-based immunotherapeutic which encodes for the six antigens Muc-1, PSA, PSCA, PSMA, STEAP-1 and PAP is described in detail in WO2015024664. 
     In a preferred embodiment, the vaccine comprises a safe and effective amount of antigen encoding RNA of the immunostimulatory composition as defined above. As used herein, “safe and effective amount” means an amount of the RNA of the immunostimulatory composition in the vaccine as defined above, that is sufficient to significantly induce a positive modification of the disease, preferably cancer, more preferably lung cancer, even more preferably of a non-small-cell lung cancer (NSCLC) related condition to be treated, more preferably of conditions related to the three main sub-types of non-small-cell lung cancer (NSCLC) including, without being restricted thereto, squamous cell lung carcinoma, adenocarcinoma and large cell lung carcinoma. At the same time, however, a “safe and effective amount” is small enough to avoid serious side-effects, that is to say to permit a sensible relationship between advantage and risk. The determination of these limits typically lies within the scope of sensible medical judgment. In relation to the vaccine, the expression “safe and effective amount” preferably means an amount of the RNA that is suitable for stimulating the adaptive immune system in such a manner that no excessive or damaging immune reactions are achieved but, preferably, also no such immune reactions below a measurable level. Such a “safe and effective amount” of the at least one RNA of the immunostimulatory composition in the vaccine as defined above may furthermore be selected in dependence of the type of RNA, e.g. monocistronic, bi- or even multicistronic RNA, since a bi- or even multicistronic RNA may lead to a significantly higher expression of the encoded antigen(s) than use of an equal amount of a monocistronic RNA. A “safe and effective amount” of the at least one RNA of the immunostimulatory composition as defined above, which is contained in the vaccine, will furthermore vary in connection with the particular condition to be treated and also with the age and physical condition of the patient to be treated, the severity of the condition, the duration of the treatment, the nature of the accompanying therapy, of the particular pharmaceutically acceptable carrier used, and similar factors, within the knowledge and experience of the accompanying doctor. 
     The vaccine typically contains a pharmaceutically acceptable carrier. The expression “pharmaceutically acceptable carrier” as used herein preferably includes the liquid or non-liquid basis of the vaccine. If the vaccine is provided in liquid form, the carrier will typically be pyrogen-free water; isotonic saline or buffered (aqueous) solutions, e.g. phosphate-, citrate-buffered solutions, etc. 
     The vaccine can additionally contain one or more auxiliary substances in order to further increase the immunogenicity. A synergistic action of the at least one RNA of the active (immunostimulatory) composition as defined above and of an auxiliary substance, which may be optionally also contained in the vaccine as described above, is preferably achieved thereby. Depending on the various types of auxiliary substances, various mechanisms can come into consideration in this respect. For example, compounds that permit the maturation of dendritic cells (DCs), for example lipopolysaccharides, TNF-alpha or CD40 ligand, form a first class of suitable auxiliary substances. In general, it is possible to use as auxiliary substance any agent that influences the immune system in the manner of a “danger signal” (LPS, GP96, etc.) or cytokines, such as GM-CSF, which allow an immune response produced by the immune-stimulating adjuvant according to the invention to be enhanced and/or influenced in a targeted manner. Particularly preferred auxiliary substances are cytokines, such as monokines, lymphokines, interleukins or chemokines, that—additional to induction of the adaptive immune response by the encoded at least two antigens—promote the innate immune response, such as IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-13, IL-14, IL-15, IL-16, IL-17, IL-18, IL-19, IL-20, IL-21, IL-22, IL-23, IL-24, IL-25, IL-26, IL-27, IL-28, IL-29, IL-30, IL-31, IL-32, IL-33, INF-alpha, IFN-beta, INF-gamma, GM-CSF, G-CSF, M-CSF, LT-beta or TNF-alpha, growth factors, such as hGH. 
     Further additives which may be included in the vaccine are emulsifiers, such as, for example, Tween®; wetting agents, such as, for example, sodium lauryl sulfate; colouring agents; taste-imparting agents, pharmaceutical carriers; tablet-forming agents; stabilizers; antioxidants; preservatives. The vaccine can also additionally contain any further compound, which is known to be immune-stimulating due to its binding affinity (as ligands) to human Toll-like receptors or due to its binding affinity (as ligands) to murine Toll-like receptors. Another class of compounds, which may be added to the vaccine, may be CpG nucleic acids, in particular CpG-RNA or CpG-DNA. A CpG-RNA or CpG-DNA can be a single-stranded CpG-DNA (ss CpG-DNA), a double-stranded CpG-DNA (dsDNA), a single-stranded CpG-RNA (ss CpG-RNA) or a double-stranded CpG-RNA (ds CpG-RNA). 
     Moreover, the invention relates to a method of determining whether a cancer patient responds to a therapeutic agent comprising the steps of
         (a) determining the difference of the expression level measured before administration of the therapeutic agent and after administration of at least one dose of the therapeutic agent of at least one marker gene selected from the group consisting of the marker genes set out in table 1 in a sample of the cancer patient to obtain a gene expression profile;   (b) determining whether the cancer patient responds to a therapeutic agent based on the gene expression profile obtained in step (a);       

     Another aspect of the invention refers to a kit, diagnostic composition or device for the analysis of the expression of at least one marker gene as described herein. In one embodiment, the invention refers to a kit, diagnostic composition or device for the analysis of the expression of at least one marker gene of table 1 comprising at least one primer and/or probe selective for determining the expression level of at least one marker gene of table 1. Some embodiments relate to a kit, diagnostic composition or device comprising at least 10 primers and/or probes, preferably at least 30 primers and/or probes, more preferably at least 50 primers and/or probes, most preferably at least 100 primers and/or probes selective for determining the expression level of at least 10, 30, 50 or 100 marker genes of table 1. A further embodiment refers to a kit, diagnostic composition or device for the analysis of the expression of at least one marker gene of table 2 comprising at least one primer and/or probe selective for determining the expression level of at least one marker gene of table 2. Some embodiments relate to a kit, diagnostic composition or device comprising at least 10 primers and/or probes, preferably at least 30 primers and/or probes, more preferably at least 50 primers and/or probes, most preferably at least 100 primers and/or probes selective for determining the expression level of at least 10, 30, 50 or 100 marker genes of table 2. In a further embodiment, the invention refers to a kit, diagnostic composition or device for the analysis of the expression of at least one marker gene of table 3 comprising at least one primer and/or probe selective for determining the expression level of at least one marker gene of table 3. Further embodiments relate to a kit, diagnostic composition or device comprising at least 10 primers and/or probes, preferably at least 30 primers and/or probes, more preferably at least 40 primers and/or probes, most preferably at least 50 primers and/or probes selective for determining the expression level of at least 10, 30, 40 or 50 marker genes of table 3. In another embodiment, the invention refers to a kit, diagnostic composition or device for the analysis of the expression of at least one marker gene of table 4 comprising at least one primer and/or probe selective for determining the expression level of at least one marker gene of table 4. Further embodiments relate to a kit, diagnostic composition or device comprising at least 10 primers and/or probes, preferably at least 20 primers and/or probes, more preferably at least 25 primers and/or probes, most preferably at least 30 primers and/or probes selective for determining the expression level of at least 10, 20, 25 or 30 marker genes of table 4. In another embodiment, the invention refers to a kit, diagnostic composition or device for the analysis of the expression of at least one marker gene, preferably at least 5 marker genes, more preferably at least 10 marker genes of table 5 comprising at least one primer and/or probe, preferably at least 5 primers and/or probes, more preferably at least 10 primers and/or probes selective for determining the expression level of at least one marker gene of table 5. 
     A further embodiment refers to a kit, diagnostic composition or device for the analysis of the expression of at least one marker gene of table 2B comprising at least one primer and/or probe selective for determining the expression level of at least one marker gene of table 2B. Some embodiments relate to a kit, diagnostic composition or device comprising at least 10 primers and/or probes, preferably at least 30 primers and/or probes, more preferably at least 50 primers and/or probes, most preferably at least 90 primers and/or probes selective for determining the expression level of at least 10, 30, 50 or 90 marker genes of table 2B. In a further embodiment, the invention refers to a kit, diagnostic composition or device for the analysis of the expression of at least one marker gene of table 3B comprising at least one primer and/or probe selective for determining the expression level of at least one marker gene of table 3B. Further embodiments relate to a kit, diagnostic composition or device comprising at least 10 primers and/or probes, preferably at least 30 primers and/or probes, more preferably at least 40 primers and/or probes, most preferably at least 40 primers and/or probes selective for determining the expression level of at least 10, 30 or 40 marker genes of table 3B. In another embodiment, the invention refers to a kit, diagnostic composition or device for the analysis of the expression of at least one marker gene of table 4B comprising at least one primer and/or probe selective for determining the expression level of at least one marker gene of table 4B. Further embodiments relate to a kit, diagnostic composition or device comprising at least 10 primers and/or probes, preferably at least 20 primers and/or probes, more preferably at least 25 primers and/or probes selective for determining the expression level of at least 10, 20 or 25 marker genes of table 4B. In another embodiment, the invention refers to a kit, diagnostic composition or device for the analysis of the expression at least one marker gene, preferably at least 5 marker genes, more preferably at least 8 marker genes of table 5 comprising at least one primer and/or probe, preferably at least 5 primers and/or probes, more preferably at least 8 primers and/or probes selective for determining the expression level of at least of at least 5 or 8 marker genes of table 5B. 
     The kit as described herein may further comprise an enzyme for primer elongation, nucleotides and/or labeling agents. 
     Another aspect of the invention refers to a microarray for the analysis of the expression of at least one marker gene as described herein. In one embodiment, the invention refers to a microarray for the analysis of the expression of at least one marker gene of table 1 comprising at least one probe selective for determining the expression level of at least one marker gene of table 1. Some embodiments relate to a microarray comprising at least 10 probes, preferably at least 30 probes, more preferably at least 50 probes, most preferably at least 100 probes selective for determining the expression level of at least 10, 30, 50 or 100 marker genes of table 1. A further embodiment refers to a microarray for the analysis of the expression of at least one marker gene of table 2 comprising at least one probe selective for determining the expression level of at least one marker gene of table 2. Some embodiments relate to a microarray comprising at least 10 probes, preferably at least 30 probes, more preferably at least 50 probes, most preferably at least 100 probes selective for determining the expression level of at least 10, 30, 50 or 100 marker genes of table 2. In a further embodiment, the invention refers to a microarray for the analysis of the expression of at least one marker gene of table 3 comprising at least one probe selective for determining the expression level of at least one marker gene of table 3. Further embodiments relate to a microarray comprising at least 10 probes, preferably at least 30 probes, more preferably at least 40 probes, most preferably at least 50 probes selective for determining the expression level of at least 10, 30, 40 or 50 marker genes of table 3. In another embodiment, the invention refers to a microarray for the analysis of the expression of at least one marker gene of table 4 comprising at least one probe selective for determining the expression level of at least one marker gene of table 4. Further embodiments relate to a microarray comprising at least 10 probes, preferably at least 20 probes, more preferably at least 25 probes, most preferably at least 30 probes selective for determining the expression level of at least 10, 20, 25 or 30 marker genes of table 4. In another embodiment, the invention refers to a microarray for the analysis of the expression of at least one marker gene, preferably at least 5 marker genes, more preferably at least 10 marker genes of table 5 comprising at least one probe, preferably at least 5 probes, more preferably at least 10 probes selective for determining the expression level of at least one marker gene of table 5. 
     A further embodiment refers to a microarray for the analysis of the expression of at least one marker gene of table 2B comprising at least one probe selective for determining the expression level of at least one marker gene of table 2B. Some embodiments relate to a microarray comprising at least 10 probes, preferably at least 30 probes, more preferably at least 50 probes, most preferably at least 90 probes selective for determining the expression level of at least 10, 30, 50 or 90 marker genes of table 2B. In a further embodiment, the invention refers to a microarray for the analysis of the expression of at least one marker gene of table 3B comprising at least one probe selective for determining the expression level of at least one marker gene of table 3B. Further embodiments relate to a microarray comprising at least 10 probes, preferably at least 30 probes, more preferably at least 40 probes selective for determining the expression level of at least 10, 30 or 40 marker genes of table 3B. In another embodiment, the invention refers to a microarray for the analysis of the expression of at least one marker gene of table 4B comprising at least one probe selective for determining the expression level of at least one marker gene of table 4B. Further embodiments relate to a microarray comprising at least 10 probes, preferably at least 20 probes, more preferably at least 25 probes selective for determining the expression level of at least 10, 20 or 25 marker genes of table 4B. In another embodiment, the invention refers to a microarray for the analysis of the expression of at least one marker gene, preferably at least 5 marker genes, more preferably at least 8 marker genes of table 5B comprising at least one probe, preferably at least 5 probes, more preferably at least 8 probes selective for determining the expression level of at least one marker gene of table 5B. 
     Another aspect of the invention refers to the use of a microarray as described herein for determining the prognosis of a cancer patient, preferably a lung cancer patient and more preferably a NSCLC patient. A further aspect of the invention refers to the use of a kit as described herein for determining the prognosis of a cancer patient, preferably a lung cancer patient and more preferably a NSCLC patient. 
     Another aspect refers to a non-transitory computer readable storage medium with an executable program stored thereon, wherein the program is for diagnosing, monitoring a subject, preferably a lung cancer patient and more preferably a NSCLC patient or determining the prognosis of a subject, preferably a lung cancer patient and more preferably a NSCLC patient and wherein the program instructs a microprocessor to perform one or more of the steps of any of the methods described herein. 
     
       
         
           
               
             
               
                 TABLE 1 
               
             
            
               
                   
               
               
                 marker genes for cancer, in particular lung cancer 
               
            
           
           
               
               
            
               
                 Description 
                 Gene Symbol 
               
               
                   
               
               
                 uncharacterized LOC572558 (LOC572558), non-coding RNA [NR_015423] 
                 LOC572558 
               
               
                 Usher syndrome 1G (autosomal recessive) (USH1G), mRNA [NM_173477] 
                 USH1G 
               
               
                 bone morphogenetic protein 2 (BMP2), mRNA [NM_001200] 
                 BMP2 
               
               
                 kinesin family member 18A (KIF18A), mRNA [NM_031217] 
                 KIF18A 
               
               
                 anillin, actin binding protein (ANLN), mRNA [NM_018685] 
                 ANLN 
               
               
                 glycoprotein V (platelet) (GPS), mRNA [NM_004488] 
                 GPS 
               
               
                 spindle and kinetochore associated complex subunit 3 (SKA3), transcript variant 
                 SKA3 
               
               
                 1, mRNA [NM_145061] 
                   
               
               
                 TTK protein kinase (TTK), transcript variant 1, mRNA [NM_003318] 
                 TTK 
               
               
                 olfactomedin 4 (OLFM4), mRNA [NM_006418] 
                 OLFM4 
               
               
                 discs, large ( Drosophila ) homolog-associated protein 5 (DLGAP5), transcript 
                 DLGAP5 
               
               
                 variant 1, mRNA [NM_014750] 
                   
               
               
                 minichromosome maintenance complex component 10 (MCM10), transcript 
                 MCM10 
               
               
                 variant 1, mRNA [NM_182751] 
                   
               
               
                 secretory leukocyte peptidase inhibitor (SLPI), mRNA [NM_003064] 
                 SLPI 
               
               
                 Fas ligand (TNF superfamily, member 6) (FASLG), mRNA [NM_000639] 
                 FASLG 
               
               
                 solute carrier family 7 (amino acid transporter light chain, L system), member 8 
                 SLC7A8 
               
               
                 (SLC7A8), transcript variant 2, mRNA [NM_182728] 
                   
               
               
                 exonuclease 1 (EXO1), transcript variant 3, mRNA [NM_003686] 
                 EXO1 
               
               
                 fibroblast growth factor binding protein 2 (FGFBP2), mRNA [NM_031950] 
                 FGFBP2 
               
               
                 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 
                 CXCL1 
               
               
                 (CXCL1), mRNA [NM_001511] 
                   
               
               
                 maternal embryonic leucine zipper kinase (MELK), mRNA [NM_014791] 
                 MELK 
               
               
                 ribonucleotide reductase M2 (RRM2), transcript variant 2, mRNA [NM_001034] 
                 RRM2 
               
               
                 KIAA0101 (KIAA0101), transcript variant 1, mRNA [NM_014736] 
                 KIAA0101 
               
               
                 interferon, alpha-inducible protein 27 (IFI27), transcript variant 2, mRNA 
                 IFI27 
               
               
                 [NM_005532] 
                   
               
               
                 RAD51 homolog ( S. cerevisiae ) (RAD51), transcript variant 1, mRNA 
                 RAD51 
               
               
                 [NM_002875] 
                   
               
               
                 thymidylate synthetase (TYMS), mRNA [NM_001071] 
                 TYMS 
               
               
                 E2F transcription factor 8 (E2F8), mRNA [NM_024680] 
                 E2F8 
               
               
                 platelet-derived growth factor receptor, beta polypeptide (PDGFRB), mRNA 
                 PDGFRB 
               
               
                 [NM_002609] 
                   
               
               
                 chitinase 3-like 1 (cartilage glycoprotein-39) (CHI3L1), mRNA [NM_001276] 
                 CHI3L1 
               
               
                 interferon, gamma (IFNG), mRNA [NM_000619] 
                 IFNG 
               
               
                 chromatin licensing and DNA replication factor 1 (CDT1), mRNA [NM_030928] 
                 CDT1 
               
               
                 chemokine (C-C motif) ligand 20 (CCL20), transcript variant 1, mRNA 
                 CCL20 
               
               
                 [NM_004591] 
                   
               
               
                 denticleless homolog ( Drosophila ) (DTL), mRNA [NM_016448] 
                 DTL 
               
               
                 uncharacterized LOC643650 (LOC643650), non-coding RNA [NR_033957] 
                 LOC643650 
               
               
                 cyclin A2 (CCNA2), mRNA [NM_001237] 
                 CCNA2 
               
               
                 regulator of G-protein signaling 9 (RGS9), transcript variant 3, mRNA 
                 RGS9 
               
               
                 [NM_001165933] 
                   
               
               
                 centrosomal protein 55 kDa (CEP55), transcript variant 1, mRNA [NM_018131]  
                 CEP55 
               
               
                 polymerase (DNA directed), epsilon 2 (p59 subunit) (POLE2), transcript variant 
                 POLE2 
               
               
                 1, mRNA [NM_002692] 
                   
               
               
                 asp (abnormal spindle) homolog, microcephaly associated ( Drosophila ) (ASPM), 
                 ASPM 
               
               
                 transcript variant 1, mRNA [NM_018136] 
                   
               
               
                 transforming growth factor, beta receptor III (TGFBR3), transcript variant 1, 
                 TGFBR3 
               
               
                 mRNA [NM_003243] 
                   
               
               
                 retinitis pigmentosa GTPase regulator interacting protein 1 (RPGRIP1), mRNA 
                 RPGRIP1 
               
               
                 [NM_020366] 
                   
               
               
                 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 
                 KIR2DL2 
               
               
                 (KIR2DL2), mRNA [NM_014219] 
                   
               
               
                 Holliday junction recognition protein (HJURP), mRNA [NM_018410] 
                 HJURP 
               
               
                 signal transducing adaptor family member 1 (STAP1), mRNA [NM_012108] 
                 STAP1 
               
               
                 topoisomerase (DNA) II alpha 170 kDa (TOP2A), mRNA [NM_001067] 
                 TOP2A 
               
               
                 TLR2_HUMAN (O60603) Toll-like receptor 2 precursor (Toll/interleukin 1 
                 XLOC_I2_010897 
               
               
                 receptor-like protein 4) (CD282 antigen), partial (33%) [THC2499145]  
                   
               
               
                 protein phosphatase 2, regulatory subunit B, beta (PPP2R2B), transcript variant 
                 PPP2R2B 
               
               
                 1, mRNA [NM_004576] 
                   
               
               
                 SPC25, NDC80 kinetochore complex component, homolog ( S. cerevisiae ) 
                 SPC25 
               
               
                 (SPC25), mRNA [NM_020675] 
                   
               
               
                 KIAA1671 (KIAA1671), mRNA [NM_001145206] 
                 KIAA1671 
               
               
                 budding uninhibited by benzimidazoles 1 homolog (yeast) (BUB1), mRNA 
                 BUB1 
               
               
                 [NM_004336] 
                   
               
               
                 G protein-coupled receptor 56 (GPR56), transcript variant 3, mRNA 
                 GPR56 
               
               
                 [NM_201525] 
                   
               
               
                 granzyme M (lymphocyte met-ase 1) (GZMM), mRNA [NM_005317] 
                 GZMM 
               
               
                 sterile alpha motif domain containing 3 (SAMD3), transcript variant 1, mRNA 
                 SAMD3 
               
               
                 [NM_001017373] 
                   
               
               
                 cathepsin W (CTSW), mRNA [NM_001335] 
                 CTSW 
               
               
                 prostaglandin F2 receptor negative regulator (PTGFRN), mRNA [NM_020440] 
                 PTGFRN 
               
               
                 BX111111 Soares_total_fetus_Nb2HF8_9w cDNA clone IMAGp998C062578, 
                 XLOC_006752 
               
               
                 mRNA sequence [BX111111] 
                   
               
               
                 granulysin (GNLY), transcript variant NKG5, mRNA [NM_006433] 
                 GNLY 
               
               
                 long intergenic non-protein coding RNA 239 (LINC00239), non-coding RNA 
                 LINC00239 
               
               
                 [NR_026774] 
                   
               
               
                 cell division cycle associated 2 (CDCA2), mRNA [NM_152562] 
                 CDCA2 
               
               
                 granzyme H (cathepsin G-like 2, protein h-CCPX) (GZMH), mRNA [NM_033423] 
                 GZMH 
               
               
                 budding uninhibited by benzimidazoles 1 homolog beta (yeast) (BUB1B), mRNA 
                 BUB1B 
               
               
                 [NM_001211] 
                   
               
               
                 ubiquitin-conjugating enzyme E2C (UBE2C), transcript variant 6, mRNA 
                 UBE2C 
               
               
                 [NM_181803] 
                   
               
               
                 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 
                 KIR2DS4 
               
               
                 (KIR2DS4), mRNA [NM_012314] 
                   
               
               
                 SLAM family member 6 (SLAMF6), transcript variant 2, mRNA [NM_052931] 
                 SLAMF6 
               
               
                 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 
                 KIR2DS2 
               
               
                 (KIR2DS2), mRNA [NM_012312] 
                   
               
               
                 BROAD Institute lincRNA (XLOC_004032), lincRNA [TCONS_00007807] 
                 XLOC_004032 
               
               
                 perforin 1 (pore forming protein) (PRF1), transcript variant 1, mRNA 
                 PRF1 
               
               
                 [NM_005041] 
                   
               
               
                 GINS complex subunit 2 (Psf2 homolog) (GINS2), mRNA [NM_016095] 
                 GINS2 
               
               
                 cell division cycle 45 homolog ( S. cerevisiae ) (CDC45), transcript variant 2, 
                 CDC45 
               
               
                 mRNA [NM_003504] 
                   
               
               
                 T-box 21 (TBX21), mRNA [NM_013351] 
                 TBX21 
               
               
                 granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 
                 GZMA 
               
               
                 (GZMA), mRNA [NM_006144] 
                   
               
               
                 natural killer cell group 7 sequence (NKG7), mRNA [NM_005601] 
                 NKG7 
               
               
                 serum/glucocorticoid regulated kinase 1 (SGK1), transcript variant 1, mRNA 
                 SGK1 
               
               
                 [NM_005627] 
                   
               
               
                 poliovirus receptor related immunoglobulin domain containing (PVRIG), mRNA 
                 PVRIG 
               
               
                 [NM_024070] 
                   
               
               
                 NIMA (never in mitosis gene a)-related kinase 2 (NEK2), transcript variant 1, 
                 NEK2 
               
               
                 mRNA [NM_002497] 
                   
               
               
                 TCR gamma alternate reading frame protein (TARP), nuclear gene encoding 
                 TARP 
               
               
                 mitochondrial protein, transcript variant 1, mRNA [NM_001003799] 
                   
               
               
                 baculoviral IAP repeat containing 5 (BIRC5), transcript variant 3, mRNA 
                 BIRC5 
               
               
                 [NM_001012271] 
                   
               
               
                 cystatin F (leukocystatin) (CST7), mRNA [NM_003650] 
                 CST7 
               
               
                 interleukin 2 receptor, beta (IL2RB), mRNA [NM_000878] 
                 IL2RB 
               
               
                 meiotic nuclear divisions 1 homolog ( S. cerevisiae ) (MND1), mRNA 
                 MND1 
               
               
                 [NM_032117] 
                   
               
               
                 sphingosine-1-phosphate receptor 5 (S1PR5), transcript variant 1, mRNA 
                 S1PR5 
               
               
                 [NM_030760] 
                   
               
               
                 serine/threonine kinase 32B (STK32B), mRNA [NM_018401] 
                 STK32B 
               
               
                 killer cell lectin-like receptor subfamily F, member 1 (KLRF1), mRNA 
                 KLRF1 
               
               
                 [NM_016523] 
                   
               
               
                 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) (ENPP5), 
                 ENPP5 
               
               
                 mRNA [NM_021572] 
                   
               
               
                 interleukin 18 receptor accessory protein (IL18RAP), mRNA [NM_003853] 
                 IL18RAP 
               
               
                 GRB2-related adaptor protein 2 (GRAP2), mRNA [NM_004810] 
                 GRAP2 
               
               
                 SH2 domain containing 2A (SH2D2A), transcript variant 5, mRNA 
                 SH2D2A 
               
               
                 [NM_001161444] 
                   
               
               
                 complement component (3b/4b) receptor 1 (Knops blood group) (CR1), 
                 CR1 
               
               
                 transcript variant S, mRNA [NM_000651] 
                   
               
               
                 IQ motif containing D [Source: HGNC Symbol;Acc: 25168] [ENST00000392574] 
                 IQCD 
               
               
                 chemokine (C-C motif) ligand 5 (CCL5), mRNA [NM_002985] 
                 CCL5 
               
               
                 killer cell lectin-like receptor subfamily D, member 1 (KLRD1), transcript variant 
                 KLRD1 
               
               
                 1, mRNA [NM_002262] 
                   
               
               
                 chemokine (C-X-C motif) receptor 3 (CXCR3), transcript variant 1, mRNA 
                 CXCR3 
               
               
                 [NM_001504] 
                   
               
               
                 CD247 molecule [Source: HGNC Symbol;Acc: 1677] [ENST00000483825] 
                 CD247 
               
               
                 zinc finger protein 697 (ZNF697), mRNA [NM_001080470] 
                 ZNF697 
               
               
                 HOP homeobox (HOPX), transcript variant 2, mRNA [NM_139211] 
                 HOPX 
               
               
                 interleukin 1, beta (IL1B), mRNA [NM_000576] 
                 IL1B 
               
               
                 killer cell lectin-like receptor subfamily C, member 1 (KLRC1), transcript variant 
                 KLRC1 
               
               
                 1, mRNA [NM_002259] 
                   
               
               
                 zinc finger protein 503 (ZNF503), mRNA [NM_032772] 
                 ZNF503 
               
               
                 BROAD Institute lincRNA (XLOC_004924), lincRNA [TCONS_00010404] 
                 XLOC_004924 
               
               
                 zeta-chain (TCR) associated protein kinase 70 kDa (ZAP70), transcript variant 1, 
                 ZAP70 
               
               
                 mRNA [NM_001079] 
                   
               
               
                 centromere protein F, 350/400 kDa (mitosin) (CENPF), mRNA [NM_016343] 
                 CENPF 
               
               
                 protein tyrosine phosphatase, receptor type, C-associated protein (PTPRCAP), 
                 PTPRCAP 
               
               
                 mRNA [NM_005608] 
                   
               
               
                 killer cell lectin-like receptor subfamily C, member 3 (KLRC3), transcript variant 
                 KLRC3 
               
               
                 2, mRNA [NM_007333] 
                   
               
               
                 Opa interacting protein 5 (OIP5), mRNA [NM_007280] 
                 OIP5 
               
               
                 pyrin and HIN domain family, member 1 [Source: HGNC Symbol;Acc: 28894] 
                 PYHIN1 
               
               
                 [ENST00000368135] 
                   
               
               
                 PREDICTED: killer cell immunoglobulin-like receptor, three domains, long 
                 KIR3DL1 
               
               
                 cytoplasmic tail, 1 (KIR3DL1), mRNA [XM_003403406] 
                   
               
               
                 free fatty acid receptor 2 (FFAR2), mRNA [NM_005306] 
                 FFAR2 
               
               
                 dedicator of cytokinesis 4 (DOCK4), mRNA [NM_014705] 
                 DOCK4 
               
               
                 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A 
                 KIR2DL5A 
               
               
                 (KIR2DL5A), mRNA [NM_020535] 
                   
               
               
                 signal transducer and activator of transcription 4 (STAT4), transcript variant 1, 
                 STAT4 
               
               
                 mRNA [NM_003151] 
                   
               
               
                 cyclin B1 (CCNB1), mRNA [NM_031966] 
                 CCNB1 
               
               
                 NLR family, CARD domain containing 3 (NLRC3), mRNA [NM_178844] 
                 NLRC3 
               
               
                 CD226 molecule (CD226), mRNA [NM_006566] 
                 CD226 
               
               
                 lin-7 homolog A ( C. elegans ) (LIN7A), mRNA [NM_004664] 
                 LIN7A 
               
               
                 coiled-coil domain containing 102A (CCDC102A), mRNA [NM_033212] 
                 CCDC102A 
               
               
                 SH3-binding domain kinase 1 (SBK1), mRNA [NM_001024401] 
                 SBK1 
               
               
                 CD1d molecule (CD1D), mRNA [NM_001766] 
                 CD1D 
               
               
                 minichromosome maintenance complex component 2 (MCM2), mRNA 
                 MCM2 
               
               
                 [NM_004526] 
                   
               
               
                 cell division cycle associated 5 
                 CDCA5 
               
               
                 cysteine-rich secretory protein LCCL domain containing 2 (CRISPLD2), mRNA 
                 CRISPLD2 
               
               
                 [NM_031476] 
                   
               
               
                 cDNA FLJ90806 fis, clone Y79AA1000750. [AK075287] 
                 SPC24 
               
               
                 TXK tyrosine kinase (TXK), mRNA [NM_003328] 
                 TXK 
               
               
                 v-myb myeloblastosis viral oncogene homolog (avian)-like 1 (MYBL1), transcript 
                 MYBL1 
               
               
                 variant 2, mRNA [NM_001144755] 
                   
               
               
                 uncharacterized protein FLJ23867 (FLJ23867), non-coding RNA [NR_026900] 
                 FLJ23867 
               
               
                 cathelicidin antimicrobial peptide (CAMP), mRNA [NM_004345] 
                 CAMP 
               
               
                 delta-like 1 ( Drosophila ) (DLL1), mRNA [NM_005618] 
                 DLL1 
               
               
                 stathmin 1 (STMN1), transcript variant 4, mRNA [NM_001145454] 
                 STMN1 
               
               
                 prostaglandin D2 receptor (DP) (PTGDR), mRNA [NM_000953] 
                 PTGDR 
               
               
                 CD7 molecule (CD7), mRNA [NM_006137] 
                 CD7 
               
               
                 BROAD Institute lincRNA (XLOC_011068), lincRNA [TCONS_00022791] 
                 XLOC_011068 
               
               
                 triggering receptor expressed on myeloid cells 1 (TREM1), transcript variant 1, 
                 TREM1 
               
               
                 mRNA [NM_018643] 
                   
               
               
                 calmin (calponin-like, transmembrane) (CLMN), mRNA [NM_024734] 
                 CLMN 
               
               
                 T cell immunoreceptor with Ig and ITIM domains (TIGIT), mRNA [NM_173799] 
                 TIGIT 
               
               
                 chloride intracellular channel 3 (CLIC3), mRNA [NM_004669] 
                 CLIC3 
               
               
                 interleukin 32 (IL32), transcript variant 1, mRNA [NM_001012631] 
                 IL32 
               
               
                 adenomatosis polyposis coli down-regulated 1 (APCDD1), mRNA [NM_153000] 
                 APCDD1 
               
               
                 zinc finger homeobox 3 (ZFHX3), transcript variant A, mRNA [NM_006885] 
                 ZFHX3 
               
               
                 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 (ST3GAL6), mRNA 
                 ST3GAL6 
               
               
                 [NM_006100] 
                   
               
               
                 chemokine (C-X-C motif) receptor 6 (CXCR6), mRNA [NM_006564] 
                 CXCR6 
               
               
                 ecotropic viral integration site 5 (EVI5), mRNA [NM_005665] 
                 EVI5 
               
               
                 cyclin-dependent kinase 1 (CDK1), transcript variant 1, mRNA [NM_001786] 
                 CDK1 
               
               
                 Q2H1E0_CHAGB (Q2H1E0) Predicted protein, partial (5%) [THC2723627] 
                 XLOC_002344 
               
               
                 growth arrest-specific 2 like 3 (GAS2L3), mRNA [NM_174942] 
                 GAS2L3 
               
               
                 BRCA1 interacting protein C-terminal helicase 1 (BRIP1), mRNA [NM_032043] 
                 BRIP1 
               
               
                 chromosome 15 open reading frame 38 (C15orf38), mRNA [NM_182616] 
                 C15orf38 
               
               
                 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N- 
                 ST6GALNAC2 
               
               
                 acetylgalactosaminide alpha-2,6-sialyltransferase 2 (ST6GALNAC2), mRNA 
                   
               
               
                 [NM_006456] 
                   
               
               
                 cDNA FLJ42228 fis, clone THYMU2041252. [AK124222] 
                 LOC100131043 
               
               
                 NLR family, pyrin domain containing 3 (NLRP3), transcript variant 3, mRNA 
                 NLRP3 
               
               
                 [NM_001079821] 
                   
               
               
                 transmembrane protein 144 (TMEM144), mRNA [NM_018342] 
                 TMEM144 
               
               
                 killer cell lectin-like receptor subfamily K, member 1 (KLRK1), mRNA 
                 KLRK1 
               
               
                 [NM_007360] 
                   
               
               
                 ELOVL fatty acid elongase 4 (ELOVL4), mRNA [NM_022726] 
                 ELOVL4 
               
               
                 chemokine (C motif) ligand 1 (XCL1), mRNA [NM_002995] 
                 XCL1 
               
               
                 Nedd4 family interacting protein 2 (NDFIP2), transcript variant 1, mRNA 
                 NDFIP2 
               
               
                 [NM_019080] 
                   
               
               
                 aryl hydrocarbon receptor (AHR), mRNA [NM_001621] 
                 AHR 
               
               
                 BROAD Institute lincRNA (XLOC_001266), lincRNA [TCONS_00001887] 
                 XLOC_001266 
               
               
                 cDNA clone IMAGE: 5312439. [BC066361] 
                 SETD7 
               
               
                 granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 
                 GZMB 
               
               
                 (GZMB), mRNA [NM_004131] 
                   
               
               
                 coagulation factor II (thrombin) receptor-like 1 (F2RL1), mRNA [NM_005242] 
                 F2RL1 
               
               
                 Src-like-adaptor 2 (SLA2), transcript variant 1, mRNA [NM_032214] 
                 SLA2 
               
               
                 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) (PTPN4), 
                 PTPN4 
               
               
                 mRNA [NM_002830] 
                   
               
               
                 chromatin assembly factor 1, subunit B (p60) (CHAF1B), mRNA [NM_005441] 
                 CHAF1B 
               
               
                 CD3d molecule, delta (CD3-TCR complex) (CD3D), transcript variant 1, mRNA 
                 CD3D 
               
               
                 [NM_000732] 
                   
               
               
                 protein kinase C, eta (PRKCH), mRNA [NM_006255] 
                 PRKCH 
               
               
                 kinesin family member 20A (KIF20A), mRNA [NM_005733] 
                 KIF20A 
               
               
                 kinesin family member C1 (KIFC1), mRNA [NM_002263] 
                 KIFC1 
               
               
                 haptoglobin (HP), transcript variant 1, mRNA [NM_005143] 
                 HP 
               
               
                 cell division cycle associated 7 (CDCA7), transcript variant 1, mRNA 
                 CDCA7 
               
               
                 [NM_031942] 
                   
               
               
                 integral membrane protein 2A (ITM2A), transcript variant 1, mRNA 
                 ITM2A 
               
               
                 [NM_004867] 
                   
               
               
                 BROAD Institute lincRNA (XLOC_011350), lincRNA [TCONS_00023505] 
                 XLOC__011350 
               
               
                 interleukin 8 (IL8), mRNA [NM_000584] 
                 IL8 
               
               
                 uncharacterized LOC79015 (LOC79015), non-coding RNA [NR_034104] 
                 LOC79015 
               
               
                 ubiquitin-conjugating enzyme E2T (putative) (UBE2T), mRNA [NM_014176] 
                 UBE2T 
               
               
                 pleckstrin homology domain containing, family F (with FYVE domain) member 1 
                 PLEKHF1 
               
               
                 (PLEKHF1), mRNA [NM_024310] 
                   
               
               
                 killer cell lectin-like receptor subfamily B, member 1 (KLRB1), mRNA 
                 KLRB1 
               
               
                 [NM_002258] 
                   
               
               
                 phospholipase B1 [Source: HGNC Symbol;Acc: 30041] [ENST00000329020] 
                 PLB1 
               
               
                 CD3g molecule, gamma (CD3-TCR complex) (CD3G), mRNA [NM_000073] 
                 CD3G 
               
               
                 NDC80 homolog, kinetochore complex component ( S. cerevisiae ) (NDC80), 
                 NDC80 
               
               
                 mRNA [NM_006101] 
                   
               
               
                 ELOVL fatty acid elongase 6 [Source: HGNC Symbol;Acc: 15829] 
                 ELOVL6 
               
               
                 [ENST00000394607] 
                   
               
               
                 cyclin-dependent kinase inhibitor 3 (CDKN3), transcript variant 1, mRNA 
                 CDKN3 
               
               
                 [NM_005192] 
                   
               
               
                 centromere protein A (CENPA), transcript variant 1, mRNA [NM_001809] 
                 CENPA 
               
               
                 ring finger protein 217 (RNF217), mRNA [NM_152553] 
                 RNF217 
               
               
                 orosomucoid 1 (ORM1), mRNA [NM_000607] 
                 ORM1 
               
               
                 ATPase, H+ transporting, lysosomal V0 subunit a1 (ATP6V0A1), transcript 
                 ATP6V0A1 
               
               
                 variant 3, mRNA [NM_005177] 
                   
               
               
                 asialoglycoprotein receptor 2 (ASGR2), transcript variant H2′, mRNA 
                 ASGR2 
               
               
                 [NM_080912] 
                   
               
               
                 ZW10 interactor (ZWINT), transcript variant 2, mRNA [NM_032997] 
                 ZWINT 
               
               
                 low density lipoprotein receptor-related protein 1 (LRP1), mRNA [NM_002332]  
                 LRP1 
               
               
                 CD6 molecule (CD6), mRNA [NM_006725] 
                 CD6 
               
               
                 G protein-coupled receptor 114 [Source: HGNC Symbol;Acc: 19010] 
                 GPR114 
               
               
                 [ENST00000349457] 
                   
               
               
                 aquaporin 9 (AQP9), mRNA [NM_020980] 
                 AQP9 
               
               
                 CD3e molecule, epsilon (CD3-TCR complex) (CD3E), mRNA [NM_000733] 
                 CD3E 
               
               
                 RAS guanyl releasing protein 1 (calcium and DAG-regulated) (RASGRP1), 
                 RASGRP1 
               
               
                 transcript variant 1, mRNA [NM_005739] 
                   
               
               
                 CD2 molecule [Source: HGNC Symbol;Acc: 1639] [ENST00000369477] 
                 CD2 
               
               
                 minichromosome maintenance complex component 4 (MCM4), transcript 
                 MCM4 
               
               
                 variant 1, mRNA [NM_005914] 
                   
               
               
                 family with sequence similarity 20, member C (FAM20C), mRNA [NM_020223] 
                 FAM20C 
               
               
                 interleukin 13 receptor, alpha 1 (IL13RA1), mRNA [NM_001560] 
                 IL13RA1 
               
               
                 cyclin B2 (CCNB2), mRNA [NM_004701] 
                 CCNB2 
               
               
                 GOSR1_HUMAN (O95249) Golgi SNAP receptor complex member 1 (28 kDa 
                 XLOC_I2_015034 
               
               
                 Golgi SNARE protein) (28 kDa cis-Golgi SNARE p28) (GOS-28), partial (51%) 
                   
               
               
                 [THC2694920] 
                   
               
               
                 protein kinase C, theta (PRKCQ), transcript variant 1, mRNA [NM_006257] 
                 PRKCQ 
               
               
                 C-type lectin domain family 4, member E (CLEC4E), mRNA [NM_014358] 
                 CLEC4E 
               
               
                 acid phosphatase, prostate (ACPP), transcript variant 1, mRNA [NM_001099] 
                 ACPP 
               
               
                 WD repeat and FYVE domain containing 3 (WDFY3), mRNA [NM_014991] 
                 WDFY3 
               
               
                 SH2 domain containing 1A (SH2D1A), transcript variant 2, mRNA 
                 SH2D1A 
               
               
                 [NM_001114937] 
                   
               
               
                 ubiquitin-like with PHD and ring finger domains 1 (UHRF1), transcript variant 2, 
                 UHRF1 
               
               
                 mRNA [NM_013282] 
                   
               
               
                 SMAD family member 1 (SMAD1), transcript variant 1, mRNA [NM_005900] 
                 SMAD1 
               
               
                 family with sequence similarity 198, member B (FAM198B), transcript variant 2, 
                 FAM198B 
               
               
                 mRNA [NM_016613] 
                   
               
               
                 glycoprotein, alpha-galactosyltransferase 1 pseudogene (GGTA1P), transcript 
                 GGTA1P 
               
               
                 variant 1, non-coding RNA [NR_003191] 
                   
               
               
                 tandem C2 domains, nuclear (TC2N), transcript variant 1, mRNA [NM_152332] 
                 TC2N 
               
               
                 BROAD Institute lincRNA (XLOC_014211), lincRNA [TCONS_00029412] 
                 XLOC__014211 
               
               
                 defective in sister chromatid cohesion 1 homolog ( S. cerevisiae ) (DSCC1), mRNA 
                 DSCC1 
               
               
                 [NM_024094] 
                   
               
               
                 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) (ETS1), transcript 
                 ETS1 
               
               
                 variant 2, mRNA [NM_005238] 
                   
               
               
                 RNA binding motif protein 47 (RBM47), transcript variant 2, mRNA 
                 RBM47 
               
               
                 [NM_019027] 
                   
               
               
                 solute carrier family 22 (organic cation/ergothioneine transporter), member 4 
                 SLC22A4 
               
               
                 (SLC22A4), mRNA [NM_003059] 
                   
               
               
                 ubiquitin associated and SH3 domain containing A (UBASH3A), transcript 
                 UBASH3A 
               
               
                 variant 1, mRNA [NM_018961] 
                   
               
               
                 centromere protein M (CENPM), transcript variant 2, mRNA [NM_001002876] 
                 CENPM 
               
               
                 toll-like receptor 2 (TLR2), mRNA [NM_003264] 
                 TLR2 
               
               
                 DENN/MADD domain containing 2D (DENND2D), mRNA [NM_024901] 
                 DENND2D 
               
               
                 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3 
                 KIR2DS3 
               
               
                 (KIR2DS3), mRNA [NM_012313] 
                   
               
               
                 CD163 molecule (CD163), transcript variant 1, mRNA [NM_004244] 
                 CD163 
               
               
                 zinc finger protein 516 (ZNF516), mRNA [NM_014643] 
                 ZNF516 
               
               
                 minichromosome maintenance complex component 6 (MCM6), mRNA 
                 MCM6 
               
               
                 [NM_005915] 
                   
               
               
                 MANSC domain containing 1 (MANSC1), mRNA [NM_018050] 
                 MANSC1 
               
               
                 SLAM family member 7 (SLAMF7), mRNA [NM_021181] 
                 SLAMF7 
               
               
                 linker for activation of T cells (LAT), transcript variant 1, mRNA [NM_014387] 
                 LAT 
               
               
                 lymphocyte-activation gene 3 (LAG3), mRNA [NM_002286] 
                 LAG3 
               
               
                 homeobox B4 (HOXB4), mRNA [NM_024015] 
                 HOXB4 
               
               
                 CD96 molecule (CD96), transcript variant 1, mRNA [NM_198196] 
                 CD96 
               
               
                 cytochrome P450, family 1, subfamily B, polypeptide 1 (CYP1B1), mRNA 
                 CYP1B1 
               
               
                 [NM_000104] 
                   
               
               
                 wntless homolog ( Drosophila ) (WLS), transcript variant 2, mRNA 
                 WLS 
               
               
                 [NM_001002292] 
                   
               
               
                 interleukin 1 receptor, type I (IL1R1), mRNA [NM_000877] 
                 IL1R1 
               
               
                 C-type lectin domain family 4, member D (CLEC4D), mRNA [NM_080387] 
                 CLEC4D 
               
               
                 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 
                 SPOCK2 
               
               
                 (SPOCK2), transcript variant 2, mRNA [NM_014767] 
                   
               
               
                 membrane bound O-acyltransferase domain containing 2 (MBOAT2), mRNA 
                 MBOAT2 
               
               
                 [NM_138799] 
                   
               
               
                 sortilin 1 (SORT1), transcript variant 1, mRNA [NM_002959] 
                 SORT1 
               
               
                 kinesin family member 15 (KIF15), mRNA [NM_020242] 
                 KIF15 
               
               
                 colony stimulating factor 3 receptor (granulocyte) (CSF3R), transcript variant 3, 
                 CSF3R 
               
               
                 mRNA [NM_156039] 
                   
               
               
                 IL2-inducible T-cell kinase (ITK), mRNA [NM_005546] 
                 ITK 
               
               
                 histamine N-methyltransferase (HNMT), transcript variant 1, mRNA 
                 HNMT 
               
               
                 [NM_006895] 
                   
               
               
                 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 (TIE1), mRNA 
                 TIE1 
               
               
                 [NM_005424] 
                   
               
               
                 protein kinase, cAMP-dependent, catalytic, beta (PRKACB), transcript variant 3, 
                 PRKACB 
               
               
                 mRNA [NM_207578] 
                   
               
               
                 CBP80/20-dependent translation initiation factor (CTIF), transcript variant 1, 
                 CTIF 
               
               
                 mRNA [NM_014772] 
                   
               
               
                 CKLF-like MARVEL transmembrane domain containing 2 (CMTM2), transcript 
                 CMTM2 
               
               
                 variant 1, mRNA [NM_144673] 
                   
               
               
                 TBC1 domain family, member 9 (with GRAM domain) (TBC1D9), mRNA 
                 TBC1D9 
               
               
                 [NM_015130] 
                   
               
               
                 serine peptidase inhibitor, Kunitz type 1 (SPINT1), transcript variant 1, mRNA 
                 SPINT1 
               
               
                 [NM_181642] 
                   
               
               
                 limb bud and heart development homolog (mouse) (LBH), mRNA [NM_030915] 
                 LBH 
               
               
                 kinesin family member 2C (KIF2C), mRNA [NM_006845] 
                 KIF2C 
               
               
                 RUN and SH3 domain containing 2 (RUSC2), mRNA [NM_014806] 
                 RUSC2 
               
               
                 granzyme K (granzyme 3; tryptase II) (GZMK), mRNA [NM_002104] 
                 GZMK 
               
               
                 CD320 molecule (CD320), transcript variant 1, mRNA [NM_016579] 
                 CD320 
               
               
                 neural cell adhesion molecule 1 (NCAM1), transcript variant 4, mRNA 
                 NCAM1 
               
               
                 [NM_001242608] 
                   
               
               
                 transmembrane and tetratricopeptide repeat containing 2 (TMTC2), mRNA 
                 TMTC2 
               
               
                 [NM_152588] 
                   
               
               
                 asialoglycoprotein receptor 1 (ASGR1), transcript variant 1, mRNA 
                 ASGR1 
               
               
                 [NM_001671] 
                   
               
               
                 FXYD domain containing ion transport regulator 6 (FXYD6), transcript variant 1, 
                 FXYD6 
               
               
                 mRNA [NM_022003] 
                   
               
               
                 cytoskeleton associated protein 2-like (CKAP2L), mRNA [NM_152515] 
                 CKAP2L 
               
               
                 oxoeicosanoid (OXE) receptor 1 (OXER1), mRNA [NM_148962] 
                 OXER1 
               
               
                 phosphorylase, glycogen, liver (PYGL), transcript variant 1, mRNA [NM_002863] 
                 PYGL 
               
               
                 sphingosine-1-phosphate receptor 3 (S1PR3), mRNA [NM_005226] 
                 S1PR3 
               
               
                 Kruppel-like factor 12 [Source: HGNC Symbol;Acc: 6346] [ENST00000472022] 
                 KLF12 
               
               
                 annexin A6 (ANXA6), transcript variant 1, mRNA [NM_001155] 
                 ANXA6 
               
               
                 B-cell CLL/lymphoma 6 (BCL6), transcript variant 2, mRNA [NM_001130845] 
                 BCL6 
               
               
                 Kruppel-like factor 5 (intestinal) (KLF5), mRNA [NM_001730] 
                 KLF5 
               
               
                 enolase 2 (gamma, neuronal) (ENO2), mRNA [NM_001975] 
                 ENO2 
               
               
                 CD27 molecule (CD27), mRNA [NM_001242] 
                 CD27 
               
               
                 retinol binding protein 7, cellular (RBP7), mRNA [NM_052960] 
                 RBP7 
               
               
                 cDNA FLJ42271 fis, clone TKIDN2015788. [AK124265] 
                 LOC100131490 
               
               
                 protein tyrosine phosphatase, non-receptor type 7 (PTPN7), transcript variant 
                 PTPN7 
               
               
                 2, mRNA [NM_080588] 
                   
               
               
                 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 
                 HSD3B7 
               
               
                 (HSD3B7), transcript variant 2, mRNA [NM_001142777] 
                   
               
               
                 ectonucleoside triphosphate diphosphohydrolase 1 [Source: HGNC 
                 ENTPD1 
               
               
                 Symbol;Acc: 3363] [ENST00000371206] 
                   
               
               
                 centromere protein K (CENPK), mRNA [NM_022145] 
                 CENPK 
               
               
                 histidine ammonia-lyase (HAL), mRNA [NM_002108] 
                 HAL 
               
               
                 G protein-coupled receptor 125 (GPR125), mRNA [NM_145290] 
                 GPR125 
               
               
                 uncharacterized LOC100289495 (LOC100289495), non-coding RNA 
                 LOC100289495 
               
               
                 [NR_040022] 
                   
               
               
                 ral guanine nucleotide dissociation stimulator-like 4 (RGL4), mRNA 
                 RGL4 
               
               
                 [NM_153615] 
                   
               
               
                 CD8b molecule (CD8B), transcript variant 5, mRNA [NM_004931] 
                 CD8B 
               
               
                 deleted in lymphocytic leukemia 1 (non-protein coding) (DLEU1), non-coding 
                 DLEU1 
               
               
                 RNA [NR_002605] 
                   
               
               
                 interleukin 18 receptor 1 (IL18R1), mRNA [NM_003855] 
                 IL18R1 
               
               
                 dachshund homolog 1 ( Drosophila ) (DACH1), transcript variant 1, mRNA 
                 DACH1 
               
               
                 [NM_080759] 
                   
               
               
                 CD8a molecule (CD8A), transcript variant 3, mRNA [NM_001145873] 
                 CD8A 
               
               
                 E2F transcription factor 7 (E2F7), mRNA [NM_203394] 
                 E2F7 
               
               
                 tumor necrosis factor receptor superfamily, member 10c, decoy without an 
                 TNFRSF10C 
               
               
                 intracellular domain (TNFRSF10C), mRNA [NM_003841] 
                   
               
               
                 TPX2, microtubule-associated, homolog ( Xenopus laevis ) (TPX2), mRNA 
                 TPX2 
               
               
                 [NM_012112] 
                   
               
               
                 toll-like receptor 5 (TLR5), mRNA [NM_003268] 
                 TLR5 
               
               
                 CD5 molecule (CD5), mRNA [NM_014207] 
                 CD5 
               
               
                 uncharacterized LOC387895 (LOC387895), non-coding RNA [NR_033878] 
                 LOC387895 
               
               
                 stabilin 1 (STABI), mRNA [NM_015136] 
                 STAB1 
               
               
                 arrestin domain containing 4 (ARRDC4), mRNA [NM_183376] 
                 ARRDC4 
               
               
                 PREDICTED: hypothetical LOC100506119, transcript variant 1 (LOC100506119), 
                 LOC100506119 
               
               
                 miscRNA [XR_108951] 
                   
               
               
                 pituitary tumor-transforming 1 (PTTG1), mRNA [NM_004219] 
                 PTTG1 
               
               
                 solute carrier family 11 (proton-coupled divalent metal ion transporters), 
                 SLC11A1 
               
               
                 member 1 (SLC11A1), mRNA [NM_000578] 
                   
               
               
                 peptidyl arginine deiminase, type IV (PADI4), mRNA [NM_012387] 
                 PADI4 
               
               
                 V-set and transmembrane domain containing 1 (VSTM1), mRNA [NM_198481] 
                 VSTM1 
               
               
                 5-oxoprolinase (ATP-hydrolysing) (OPLAH), mRNA [NM_017570] 
                 OPLAH 
               
               
                 peptidyl arginine deiminase, type II (PADI2), mRNA [NM_007365] 
                 PADI2 
               
               
                 solute carrier family 38, member 1 [Source: HGNC Symbol;Acc: 13447] 
                 SLC38A1 
               
               
                 [ENST00000550173] 
                   
               
               
                 carbohydrate (chondroitin 4) sulfotransferase 12 (CHST12), transcript variant 3, 
                 CHST12 
               
               
                 mRNA [NM_018641] 
                   
               
               
                 actin binding LIM protein 1 (ABLIM1), transcript variant 3, mRNA 
                 ABLIM1 
               
               
                 [NM_001003408] 
                   
               
               
                 cation channel, sperm associated 1 (CATSPER1), mRNA [NM_053054] 
                 CATSPER1 
               
               
                 cat eye syndrome chromosome region, candidate 6 (CECR6), transcript variant 
                 CECR6 
               
               
                 1, mRNA [NM_031890] 
                   
               
               
                 toll-like receptor 6 (TLR6), mRNA [NM_006068] 
                 TLR6 
               
               
                 sialic acid binding Ig-like lectin 9 (SIGLEC9), transcript variant 2, mRNA 
                 SIGLEC9 
               
               
                 [NM_014441] 
                   
               
               
                 homeobox B2 (HOXB2), mRNA [NM_002145] 
                 HOXB2 
               
               
                 plexin domain containing 2 (PLXDC2), mRNA [NM_032812] 
                 PLXDC2 
               
               
                 cAMP responsive element binding protein 5 (CREB5), transcript variant 1, 
                 CREB5 
               
               
                 mRNA [NM_182898] 
                   
               
               
                 uncharacterized LOC100240735 (LOC100240735), non-coding RNA 
                 LOC100240735 
               
               
                 [NR_026658] 
                   
               
               
                 3-hydroxyanthranilate 3,4-dioxygenase [Source: HGNC Symbol;Acc: 4796] 
                 HAAO 
               
               
                 [ENST00000402268] 
                   
               
               
                 solute carrier family 8 (sodium/calcium exchanger), member 1 (SLC8A1), 
                 SLC8A1 
               
               
                 transcript variant A, mRNA [NM_021097] 
                   
               
               
                 signaling threshold regulating transmembrane adaptor 1 (SIT1), mRNA 
                 SIT1 
               
               
                 [NM_014450] 
                   
               
               
                 NUF2, NDC80 kinetochore complex component, homolog ( S. cerevisiae ) 
                 NUF2 
               
               
                 (NUF2), transcript variant 1, mRNA [NM_145697] 
                   
               
               
                 B-cell CLL/lymphoma 11B (zinc finger protein) (BCL11B), transcript variant 1, 
                 BCL11B 
               
               
                 mRNA [NM_138576] 
                   
               
               
                 activated leukocyte cell adhesion molecule (ALCAM), transcript variant 1, 
                 ALCAM 
               
               
                 mRNA [NM_001627] 
                   
               
               
                 BAH domain and coiled-coil containing 1 (BAHCC1), mRNA [NM_001080519] 
                 BAHCC1 
               
               
                 lipase, hormone-sensitive (LIPE), mRNA [NM_005357] 
                 LIPE 
               
               
                 B and T lymphocyte associated (BTLA), transcript variant 1, mRNA 
                 BTLA 
               
               
                 [NM_181780] 
                   
               
               
                 family with sequence similarity 169, member A (FAM169A), mRNA 
                 FAM169A 
               
               
                 [NM_015566] 
                   
               
               
                 RAD54-like ( S. cerevisiae ) (RAD54L), transcript variant 1, mRNA [NM_003579]  
                 RAD54L 
               
               
                 proline/serine-rich coiled-coil 1 (PSRC1), transcript variant 1, mRNA 
                 PSRC1 
               
               
                 [NM_032636] 
                   
               
               
                 poliovirus receptor (PVR), transcript variant 1, mRNA [NM_006505] 
                 PVR 
               
               
                 inducible T-cell co-stimulator (ICOS), mRNA [NM_012092] 
                 ICOS 
               
               
                 RAD51 associated protein 1 (RAD51AP1), transcript variant 2, mRNA 
                 RAD51AP1 
               
               
                 [NM_006479] 
                   
               
               
                 ras homolog gene family, member H (RHOH), mRNA [NM_004310] 
                 RHOH 
               
               
                 cytidine deaminase (CDA), mRNA [NM_001785] 
                 CDA 
               
               
                 WD repeat domain 67 (WDR67), transcript variant 2, mRNA [NM_001145088] 
                 WDR67 
               
               
                 lymphoid enhancer-binding factor 1 (LEF1), transcript variant 1, mRNA 
                 LEF1 
               
               
                 [NM_016269] 
                   
               
               
                 CD40 ligand (CD40LG), mRNA [NM_000074] 
                 CD40LG 
               
               
                 CD93 molecule (CD93), mRNA [NM_012072] 
                 CD93 
               
               
                 solute carrier family 16, member 5 (monocarboxylic acid transporter 6) 
                 SLC16A5 
               
               
                 (SLC16A5), mRNA [NM_004695] 
                   
               
               
                 family with sequence similarity 7, member A1 (non-protein coding) (FAM7A1), 
                 FAM7A1 
               
               
                 non-coding RNA [NR_026858] 
                   
               
               
                 H2.0-like homeobox (HLX), mRNA [NM_021958] 
                 HLX 
               
               
                 frizzled family receptor 1 (FZD1), mRNA [NM_003505] 
                 FZD1 
               
               
                 transcription factor 7 (T-cell specific, HMG-box) (TCF7), transcript variant 1, 
                 TCF7 
               
               
                 mRNA [NM_003202] 
                   
               
               
                 C-type lectin domain family 7, member A (CLEC7A), transcript variant 6, mRNA 
                 CLEC7A 
               
               
                 [NM_197954] 
                   
               
               
                 RAS guanyl releasing protein 4 (RASGRP4), transcript variant a, mRNA 
                 RASGRP4 
               
               
                 [NM_170604] 
                   
               
               
                 S100 calcium binding protein Z (S100Z), mRNA [NM_130772] 
                 S100Z 
               
               
                 solute carrier family 36 (proton/amino acid symporter), member 1 (SLC36A1), 
                 SLC36A1 
               
               
                 mRNA [NM_078483] 
                   
               
               
                 interleukin-1 receptor-associated kinase 3 (IRAK3), transcript variant 1, mRNA 
                 IRAK3 
               
               
                 [NM_007199] 
                   
               
               
                 RALBP1 associated Eps domain containing 2 (REPS2), transcript variant 1, 
                 REPS2 
               
               
                 mRNA [NM_004726] 
                   
               
               
                 cell division cycle associated 8 (CDCA8), mRNA [NM_018101] 
                 CDCA8 
               
               
                 calcium channel, voltage-dependent, alpha 2/delta subunit 3 (CACNA2D3), 
                 CACNA2D3 
               
               
                 mRNA [NM_018398] 
                   
               
               
                 ATPase, class II, type 9A (ATP9A), mRNA [NM_006045] 
                 ATP9A 
               
               
                 toll-like receptor 4 (TLR4), transcript variant 1, mRNA [NM_138554] 
                 TLR4 
               
               
                 complement component 5a receptor 1 (C5AR1), mRNA [NM_001736] 
                 C5AR1 
               
               
                 junction plakoglobin (JUP), transcript variant 1, mRNA [NM_002230] 
                 JUP 
               
               
                 ribonuclease, RNase A family, k6 (RNASE6), mRNA [NM_005615] 
                 RNASE6 
               
               
                 steroid 5 alpha-reductase 3 (SRD5A3), mRNA [NM_024592] 
                 SRD5A3 
               
               
                 vanin 3 (VNN3), transcript variant 1, non-coding RNA [NR_028291] 
                 VNN3 
               
               
                 neutrophil cytosolic factor 4, 40 kDa (NCF4), transcript variant 1, mRNA 
                 NCF4 
               
               
                 [NM_000631] 
                   
               
               
                 C3 and PZP-like, alpha-2-macroglobulin domain containing 8 (CPAMD8), mRNA 
                 CPAMD8 
               
               
                 [NM_015692] 
                   
               
               
                 inositol(myo)-1(or 4)-monophosphatase 2 (IMPA2), mRNA [NM_014214] 
                 IMPA2 
               
               
                 dual specificity phosphatase 6 (DUSP6), transcript variant 1, mRNA 
                 DUSP6 
               
               
                 [NM_001946] 
                   
               
               
                 solute carrier family 1 (glial high affinity glutamate transporter), member 3 
                 SLC1A3 
               
               
                 (SLC1A3), transcript variant 1, mRNA [NM_004172] 
                   
               
               
                 STEAP family member 4 (STEAP4), transcript variant 2, mRNA [NM_001205315] 
                 STEAP4 
               
               
                 signal-regulatory protein alpha (SIRPA), transcript variant 1, mRNA 
                 SIRPA 
               
               
                 [NM_001040022] 
                   
               
               
                 prokineticin 2 (PROK2), transcript variant 2, mRNA [NM_021935] 
                 PROK2 
               
               
                 homer homolog 3 ( Drosophila ) (HOMER3), transcript variant 2, mRNA 
                 HOMER3 
               
               
                 [NM_004838] 
                   
               
               
                 proliferating cell nuclear antigen (PCNA), transcript variant 1, mRNA 
                 PCNA 
               
               
                 [NM_002592] 
                   
               
               
                 ALU5_HUMAN (P39192) Alu subfamily Sc sequence contamination warning 
                 LOC100506190 
               
               
                 entry, partial (9%) [THC2542147] 
                   
               
               
                 leucine rich repeat neuronal 3 (LRRN3), transcript variant 3, mRNA 
                 LRRN3 
               
               
                 [NM_018334] 
                   
               
               
                 pellino homolog 3 ( Drosophila ) (PELI3), transcript variant 1, mRNA 
                 PELI3 
               
               
                 [NM_145065] 
                   
               
               
                 glycosyltransferase 1 domain containing 1 (GLT1D1), mRNA [NM_144669] 
                 GLT1D1 
               
               
                 T cell receptor associated transmembrane adaptor 1 (TRAT1), mRNA 
                 TRAT1 
               
               
                 [NM_016388] 
                   
               
               
                 interferon gamma receptor 2 (interferon gamma transducer 1) (IFNGR2), mRNA 
                 IFNGR2 
               
               
                 [NM_005534] 
                   
               
               
                 versican (VCAN), transcript variant 1, mRNA [NM_004385] 
                 VCAN 
               
               
                 fructose-1,6-bisphosphatase 1 (FBP1), transcript variant 1, mRNA [NM_000507] 
                 FBP1 
               
               
                 activating transcription factor 3 (ATF3), transcript variant 4, mRNA 
                 ATF3 
               
               
                 [NM_001040619] 
                   
               
               
                 thymocyte selection associated (THEMIS), transcript variant 1, mRNA 
                 THEMIS 
               
               
                 [NM_001164685] 
                   
               
               
                 aldehyde dehydrogenase 18 family, member A1 (ALDH18A1), nuclear gene 
                 ALDH18A1 
               
               
                 encoding mitochondrial protein, transcript variant 1, mRNA [NM_002860] 
                   
               
               
                 platelet-activating factor receptor (PTAFR), transcript variant 2, mRNA 
                 PTAFR 
               
               
                 [NM_001164722] 
                   
               
               
                 kinesin family member 14 (KIF14), mRNA [NM_014875] 
                 KIF14 
               
               
                 cyclin E2 (CCNE2), mRNA [NM_057749] 
                 CCNE2 
               
               
                 potassium voltage-gated channel, Isk-related family, member 3 (KCNE3), mRNA 
                 KCNE3 
               
               
                 [NM_005472] 
                   
               
               
                 fidgetin-like 1 (FIGNL1), transcript variant 1, mRNA [NM_001042762] 
                 FIGNL1 
               
               
                 myeloid cell nuclear differentiation antigen (MNDA), mRNA [NM_002432] 
                 MNDA 
               
               
                 PREDICTED: hypothetical protein LOC100652853 (LOC100652853), mRNA 
                 HP07349 
               
               
                 [XM_003403534] 
                   
               
               
                 carboxypeptidase, vitellogenic-like (CPVL), transcript variant 2, mRNA 
                 CPVL 
               
               
                 [NM_019029] 
                   
               
               
                 claudin 23 (CLDN23), mRNA [NM_194284] 
                 CLDN23 
               
               
                 cancer susceptibility candidate 5 (CASC5), transcript variant 1, mRNA 
                 CASC5 
               
               
                 [NM_170589] 
                   
               
               
                 inositol 1,4,5-trisphosphate receptor, type 3 (ITPR3), mRNA [NM_002224] 
                 ITPR3 
               
               
                 ral guanine nucleotide dissociation stimulator-like 1 (RGL1), mRNA 
                 RGL1 
               
               
                 [NM_015149] 
                   
               
               
                 transmembrane 6 superfamily member 1 (TM6SF1), transcript variant 1, mRNA 
                 TM6SF1 
               
               
                 [NM_023003] 
                   
               
               
                 solute carrier family 22, member 15 (SLC22A15), mRNA [NM_018420] 
                 SLC22A15 
               
               
                 BMP2 inducible kinase (BMP2K), transcript variant 2, mRNA [NM_017593] 
                 BMP2K 
               
               
                 RAR-related orphan receptor A (RORA), transcript variant 2, mRNA 
                 RORA 
               
               
                 [NM_134260] 
                   
               
               
                 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) (ENPP4), 
                 ENPP4 
               
               
                 mRNA [NM_014936] 
                   
               
               
                 minichromosome maintenance complex component 3 (MCM3), mRNA 
                 MCM3 
               
               
                 [NM_002388] 
                   
               
               
                 complement component 3a receptor 1 (C3AR1), mRNA [NM_004054] 
                 C3AR1 
               
               
                 B-cell CLL/lymphoma 2 (BCL2), nuclear gene encoding mitochondrial protein, 
                 BCL2 
               
               
                 transcript variant alpha, mRNA [NM_000633] 
                   
               
               
                 leucine-rich alpha-2-glycoprotein 1 (LRG1), mRNA [NM_052972] 
                 LRG1 
               
               
                 NACC family member 2, BEN and BTB (POZ) domain containing (NACC2), mRNA 
                 NACC2 
               
               
                 [NM_144653] 
                   
               
               
                 growth arrest-specific 2 like 1 (GAS2L1), transcript variant 3, mRNA 
                 GAS2L1 
               
               
                 [NM_152237] 
                   
               
               
                 RAS p21 protein activator 3 (RASA3), mRNA [NM_007368] 
                 RASA3 
               
               
                 C-type lectin domain family 12, member A (CLEC12A), transcript variant 1, 
                 CLEC12A 
               
               
                 mRNA [NM_138337] 
                   
               
               
                 centromere protein O (CENPO), transcript variant 1, mRNA [NM_024322] 
                 CENPO 
               
               
                 phospholipase B domain containing 1 (PLBD1), mRNA [NM_024829] 
                 PLBD1 
               
               
                 interferon gamma receptor 1 (IFNGR1), mRNA [NM_000416] 
                 IFNGR1 
               
               
                 aurora kinase A (AURKA), transcript variant 1, mRNA [NM_198433] 
                 AURKA 
               
               
                 fms-related tyrosine kinase 3 ligand (FLT3LG), transcript variant 3, mRNA 
                 FLT3LG 
               
               
                 [NM_001459] 
                   
               
               
                 cytoplasmic FMR1 interacting protein 1 (CYFIP1), transcript variant 1, mRNA 
                 CYFIP1 
               
               
                 [NM_014608] 
                   
               
               
                 kallikrein-related peptidase 3 (KLK3), transcript variant 3, mRNA 
                 KLK3 
               
               
                 [NM_001030047] 
                   
               
               
                 diacylglycerol O-acyltransferase 2 (DGAT2), mRNA [NM_032564] 
                 DGAT2 
               
               
                 KIAA1598 (KIAA1598), transcript variant 1, mRNA [NM_001127211] 
                 KIAA1598 
               
               
                 lymphocyte-specific protein tyrosine kinase (LCK), transcript variant 2, mRNA 
                 LCK 
               
               
                 [NM_005356] 
                   
               
               
                 thyroid hormone receptor interactor 13 (TRIP13), transcript variant 1, mRNA 
                 TRIP13 
               
               
                 [NM_004237] 
                   
               
               
                 disrupted in renal carcinoma 2 (DIRC2), mRNA [NM_032839] 
                 DIRC2 
               
               
                 RAB13, member RAS oncogene family (RAB13), mRNA [NM_002870] 
                 RAB13 
               
               
                 leucine rich repeat containing 4 (LRRC4), mRNA [NM_022143] 
                 LRRC4 
               
               
                 PREDICTED: hypothetical protein LOC100130458 (LOC100130458), mRNA 
                 LOC100130458 
               
               
                 [XM_001716901] 
                   
               
               
                 mal, T-cell differentiation protein (MAL), transcript variant a, mRNA 
                 MAL 
               
               
                 [NM_002371] 
                   
               
               
                 tensin 3 (TNS3), mRNA [NM_022748] 
                 TNS3 
               
               
                 lysophosphatidylcholine acyltransferase 2 (LPCAT2), mRNA [NM_017839] 
                 LPCAT2 
               
               
                 DENN/MADD domain containing 1A (DENND1A), transcript variant 2, mRNA 
                 DENND1A 
               
               
                 [NM_024820] 
                   
               
               
                 protein phosphatase 1, regulatory subunit 32 (PPP1R32), nuclear gene 
                 PPP1R32 
               
               
                 encoding mitochondrial protein, transcript variant 1, mRNA [NM_145017] 
                   
               
               
                 cDNA FLJ45829 fis, clone NT2RP8006452. [AK127729] 
                 LRRK2 
               
               
                 membrane-associated ring finger (C3HC4) 1 (MARCH1), transcript variant 2, 
                 MARCH1 
               
               
                 mRNA [NM_017923] 
                   
               
               
                 cold shock domain protein A (CSDA), transcript variant 1, mRNA [NM_003651] 
                 CSDA 
               
               
                 GATA binding protein 3 (GATA3), transcript variant 1, mRNA [NM_001002295]  
                 GATA3 
               
               
                 microsomal glutathione S-transferase 1 (MGST1), transcript variant 1c, mRNA 
                 MGST1 
               
               
                 [NM_145791] 
                   
               
               
                 calcium/calmodulin-dependent protein kinase IV (CAMK4), mRNA 
                 CAMK4 
               
               
                 [NM_001744] 
                   
               
               
                 minichromosome maintenance complex component 8 (MCM8), transcript 
                 MCM8 
               
               
                 variant 2, mRNA [NM_182802] 
                   
               
               
                 BROAD Institute lincRNA (XLOC_014161), lincRNA [TCONS_00029333] 
                 XLOC__014161 
               
               
                 coatomer protein complex, subunit gamma 2 (COPG2), mRNA [NM_012133] 
                 COPG2 
               
               
                 tumor protein p53 inducible protein 3 (TP53I3), transcript variant 1, mRNA 
                 TP53I3 
               
               
                 [NM_004881] 
                   
               
               
                 egf-like module containing, mucin-like, hormone receptor-like 2 (EMR2), 
                 EMR2 
               
               
                 transcript variant 1, mRNA [NM_013447] 
                   
               
               
                 vanin 1 (VNN1), mRNA [NM_004666] 
                 VNN1 
               
               
                 kinesin family member 11 (KIF11), mRNA [NM_004523] 
                 KIF11 
               
               
                 mutS homolog 2, colon cancer, nonpolyposis type 1 ( E. coli ) (MSH2), mRNA 
                 MSH2 
               
               
                 [NM_000251] 
                   
               
               
                 WEE1 homolog ( S. pombe ) (WEE1), transcript variant 1, mRNA [NM_003390] 
                 WEE1 
               
               
                 purinergic receptor P2Y, G-protein coupled, 13 (P2RY13), mRNA [NM_176894] 
                 P2RY13 
               
               
                 helicase (DNA) B (HELB), mRNA [NM_033647] 
                 HELB 
               
               
                 tetratricopeptide repeat and ankyrin repeat containing 1 (TRANK1), mRNA 
                 TRANK1 
               
               
                 [NM_014831] 
                   
               
               
                 chemokine (C-C motif) receptor 1 (CCR1), mRNA [NM_001295] 
                 CCR1 
               
               
                 PREDICTED: hypothetical LOC100505921 (LOC100505921), miscRNA 
                 LOC100505921 
               
               
                 [XR_108739] 
                   
               
               
                 lipoma HMGIC fusion partner-like 2 (LHFPL2), mRNA [NM_005779] 
                 LHFPL2 
               
               
                 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 
                 SLC24A4 
               
               
                 (SLC24A4), transcript variant 2, mRNA [NM_153647] 
                   
               
               
                 lactotransferrin (LTF), transcript variant 1, mRNA [NM_002343] 
                 LTF 
               
               
                 Fc receptor-like 5 (FCRL5), transcript variant 2, mRNA [NM_001195388] 
                 FCRL5 
               
               
                 protocadherin 9 (PCDH9), transcript variant 1, mRNA [NM_203487] 
                 PCDH9 
               
               
                 retinoblastoma-like 1 (p107) (RBL1), transcript variant 1, mRNA [NM_002895]  
                 RBL1 
               
               
                 MAD2 mitotic arrest deficient-like 1 (yeast) (MAD2L1), mRNA [NM_002358] 
                 MAD2L1 
               
               
                 SHC SH2-domain binding protein 1 (SHCBP1), mRNA [NM_024745] 
                 SHCBP1 
               
               
                 folate receptor 3 (gamma) (FOLR3), mRNA [NM_000804] 
                 FOLR3 
               
               
                 aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2), nuclear gene 
                 ALDH2 
               
               
                 encoding mitochondrial protein, transcript variant 1, mRNA [NM_000690] 
                   
               
               
                 transforming growth factor, beta-induced, 68 kDa (TGFBI), mRNA [NM_000358] 
                 TGFBI 
               
               
                 lymphocyte antigen 96 (LY96), transcript variant 1, mRNA [NM_015364] 
                 LY96 
               
               
                 galactosidase, beta 1-like (GLB1L), mRNA [NM_024506] 
                 GLB1L 
               
               
                 NEL-like 2 (chicken) (NELL2), transcript variant 2, mRNA [NM_006159] 
                 NELL2 
               
               
                 serine carboxypeptidase 1 (SCPEP1), mRNA [NM_021626] 
                 SCPEP1 
               
               
                 v-myb myeloblastosis viral oncogene homolog (avian)-like 2 (MYBL2), mRNA 
                 MYBL2 
               
               
                 [NM_002466] 
                   
               
               
                 dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive) (DYSF), 
                 DYSF 
               
               
                 transcript variant 8, mRNA [NM_003494] 
                   
               
               
                 NLR family, apoptosis inhibitory protein (NAIP), transcript variant 1, mRNA 
                 NAIP 
               
               
                 [NM_004536] 
                   
               
               
                 CD36 molecule (thrombospondin receptor) (CD36), transcript variant 2, mRNA 
                 CD36 
               
               
                 [NM_001001547] 
                   
               
               
                 lymphocyte antigen 86 (LY86), mRNA [NM_004271] 
                 LY86 
               
               
                 PML-RARA regulated adaptor molecule 1 (PRAM1), mRNA [NM_032152] 
                 PRAM1 
               
               
                 interleukin 7 receptor (IL7R), mRNA [NM_002185] 
                 IL7R 
               
               
                 PDZ and LIM domain 7 (enigma) (PDLIM7), transcript variant 1, mRNA 
                 PDLIM7 
               
               
                 [NM_005451] 
                   
               
               
                 membrane-spanning 4-domains, subfamily A, member 4 (MS4A4A), transcript 
                 MS4A4A 
               
               
                 variant 2, mRNA [NM_024021] 
                   
               
               
                 Fc fragment of IgG, low affinity IIa, receptor (CD32) (FCGR2A), transcript variant 
                 FCGR2A 
               
               
                 2, mRNA [NM_021642] 
                   
               
               
                 dedicator of cytokinesis 5 (DOCK5), mRNA [NM_024940] 
                 DOCK5 
               
               
                 RAB34, member RAS oncogene family (RAB34), transcript variant 3, mRNA 
                 RAB34 
               
               
                 [NM_001142625] 
                   
               
               
                 cytochrome b reductase 1 (CYBRD1), transcript variant 1, mRNA [NM_024843] 
                 CYBRD1 
               
               
                 ribonuclease, RNase A family, 3 (RNASE3), mRNA [NM_002935] 
                 RNASE3 
               
               
                 heparanase (HPSE), transcript variant 1, mRNA [NM_006665] 
                 HPSE 
               
               
                 elastase, neutrophil expressed (]LANE), mRNA [NM_001972] 
                 ]LANE 
               
               
                 ring finger protein 24 (RNF24), transcript variant 1, mRNA [NM_007219] 
                 RNF24 
               
               
                 myeloid-associated differentiation marker (MYADM), transcript variant 1, 
                 MYADM 
               
               
                 mRNA [NM_001020818] 
                   
               
               
                 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, 
                 SMARCD3 
               
               
                 subfamily d, member 3 (SMARCD3), transcript variant 2, mRNA [NM_003078] 
                   
               
               
                 membrane-spanning 4-domains, subfamily A, member 6A (MS4A6A), transcript 
                 MS4A6A 
               
               
                 variant 1, mRNA [NM_152852] 
                   
               
               
                 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM 
                 LILRB3 
               
               
                 domains), member 3 (LILRB3), transcript variant 2, mRNA [NM_006864] 
                   
               
               
                 lipid phosphate phosphatase-related protein type 2 (LPPR2), transcript variant 
                 LPPR2 
               
               
                 1, mRNA [NM_022737] 
                   
               
               
                 flap structure-specific endonuclease 1 (FEN1), mRNA [NM_004111] 
                 FEN1 
               
               
                 toll-like receptor 8 (TLR8), mRNA [NM_138636] 
                 TLR8 
               
               
                 G protein-coupled receptor 171 (GPR171), mRNA [NM_013308] 
                 GPR171 
               
               
                 platelet/endothelial cell adhesion molecule (PECAM1), mRNA [NM_000442] 
                 PECAM1 
               
               
                 renin binding protein (RENBP), mRNA [NM_002910] 
                 RENBP 
               
               
                 interleukin 18 (interferon-gamma-inducing factor) (IL18), transcript variant 1, 
                 IL18 
               
               
                 mRNA [NM_001562] 
                   
               
               
                 complement factor D (adipsin) (CFD), mRNA [NM_001928] 
                 CFD 
               
               
                 ArfGAP with dual PH domains 2 (ADAP2), mRNA [NM_018404] 
                 ADAP2 
               
               
                 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) (PRRG4), mRNA 
                 PRRG4 
               
               
                 [NM_024081] 
                   
               
               
                 LIM domain only 2 (rhombotin-like 1) (LMO2), transcript variant 1, mRNA 
                 LMO2 
               
               
                 [NM_005574] 
                   
               
               
                 replication protein A2, 32 kDa (RPA2), mRNA [NM_002946] 
                 RPA2 
               
               
                 IMP1 inner mitochondrial membrane peptidase-like ( S. cerevisiae ) (IMMP1L), 
                 IMMP1L 
               
               
                 nuclear gene encoding mitochondrial protein, mRNA [NM_144981] 
                   
               
               
                 RAB31, member RAS oncogene family (RAB31), mRNA [NM_006868] 
                 RAB31 
               
               
                 multiple C2 domains, transmembrane 1 (MCTP1), transcript variant L, mRNA 
                 MCTP1 
               
               
                 [NM_024717] 
                   
               
               
                 biliverdin reductase B (flavin reductase (NADPH)) (BLVRB), mRNA [NM_000713]  
                 BLVRB 
               
               
                 signaling lymphocytic activation molecule family member 1 (SLAMF1), mRNA 
                 SLAMF1 
               
               
                 [NM_003037] 
                   
               
               
                 serglycin (SRGN), transcript variant 1, mRNA [NM_002727] 
                 SRGN 
               
               
                 potassium channel tetramerisation domain containing 12 (KCTD12), mRNA 
                 KCTD12 
               
               
                 [NM_138444] 
                   
               
               
                 TIMP metallopeptidase inhibitor 2 (TIMP2), mRNA [NM_003255] 
                 TIMP2 
               
               
                 eomesodermin (EOMES), mRNA [NM_005442] 
                 EOMES 
               
               
                 solute carrier family 7 (amino acid transporter light chain, y + L system), member 
                 SLC7A7 
               
               
                 7 (SLC7A7), transcript variant 3, mRNA [NM_001126106] 
                   
               
               
                 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), 
                 LILRA3 
               
               
                 member 3 (LILRA3), transcript variant 1, mRNA [NM_006865] 
                   
               
               
                 sialic acid binding Ig-like lectin 15 (SIGLEC15), mRNA [NM_213602] 
                 SIGLEC15 
               
               
                 DNA-damage regulated autophagy modulator 1 (DRAM1), mRNA [NM_018370] 
                 DRAM1 
               
               
                 cell division cycle associated 3 (CDCA3), mRNA [NM_031299] 
                 CDCA3 
               
               
                 sulfatase 2 (SULF2), transcript variant 1, mRNA [NM_018837] 
                 SULF2 
               
               
                 lectin, galactoside-binding, soluble, 3 (LGALS3), transcript variant 1, mRNA 
                 LGALS3 
               
               
                 [NM_002306] 
                   
               
               
                 NLR family, pyrin domain containing 12 (NLRP12), transcript variant 1, mRNA 
                 NLRP12 
               
               
                 [NM_033297] 
                   
               
               
                 CD33 molecule (CD33), transcript variant 1, mRNA [NM_001772] 
                 CD33 
               
               
                 inositol 1,4,5-trisphosphate receptor interacting protein-like 2 (ITPRIPL2), 
                 ITPRIPL2 
               
               
                 transcript variant 1, mRNA [NM_001034841] 
                   
               
               
                 cell division cycle 20 homolog ( S. cerevisiae ) (CDC20), mRNA [NM_001255] 
                 CDC20 
               
               
                 transmembrane protein 127 (TMEM127), transcript variant 1, mRNA 
                 TMEM127 
               
               
                 [NM_017849] 
                   
               
               
                 GTPase, IMAP family member 7 (GIMAP7), mRNA [NM_153236] 
                 GIMAP7 
               
               
                 calcineurin-like phosphoesterase domain containing 1 (CPPED1), transcript 
                 CPPED1 
               
               
                 variant 1, mRNA [NM_018340] 
                   
               
               
                 Fanconi anemia, complementation group I (FANCI), transcript variant 2, mRNA 
                 FANCI 
               
               
                 [NM_018193] 
                   
               
               
                 akirin 2 (AKIRIN2), mRNA [NM_018064] 
                 AKIRIN2 
               
               
                 S100 calcium binding protein A12 (S100A12), mRNA [NM_005621] 
                 S100A12 
               
               
                 serine threonine kinase 39 (STK39), mRNA [NM_013233] 
                 STK39 
               
               
                 C-type lectin domain family 10, member A (CLEC10A), transcript variant 1, 
                 CLEC10A 
               
               
                 mRNA [NM_182906] 
                   
               
               
                 CD68 molecule (CD68), transcript variant 1, mRNA [NM_001251] 
                 CD68 
               
               
                 E2F transcription factor 5, p130-binding (E2F5), transcript variant 1, mRNA 
                 E2F5 
               
               
                 [NM_001951] 
                   
               
               
                 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 
                 CHST15 
               
               
                 (CHST15), transcript variant 2, mRNA [NM_014863] 
                   
               
               
                 zinc finger protein 668 (ZNF668), transcript variant 1, mRNA [NM_001172668]  
                 ZNF668 
               
               
                 C-type lectin domain family 4, member A (CLEC4A), transcript variant 1, mRNA 
                 CLEC4A 
               
               
                 [NM_016184] 
                   
               
               
                 osteoclast associated, immunoglobulin-like receptor (OSCAR), transcript variant 
                 OSCAR 
               
               
                 1, mRNA [NM_206818] 
                   
               
               
                 CD28 molecule (CD28), transcript variant 1, mRNA [NM_006139] 
                 CD28 
               
               
                 cystatin A (stefin A) (CSTA), mRNA [NM_005213] 
                 CSTA 
               
               
                 transmembrane protein 64 (TMEM64), transcript variant 1, mRNA 
                 TMEM64 
               
               
                 [NM_001008495] 
                   
               
               
                 glycosyltransferase 25 domain containing 1 (GLT25D1), mRNA [NM_024656] 
                 GLT25D1 
               
               
                 lectin, galactoside-binding, soluble, 2 (LGALS2), mRNA [NM_006498] 
                 LGALS2 
               
               
                 6-phosphofructo-2-kinasegructose-2,6-biphosphatase 4 (PFKFB4), mRNA 
                 PFKFB4 
               
               
                 [NM_004567] 
                   
               
               
                 adhesion molecule, interacts with CXADR antigen 1 (AMICA1), transcript variant 
                 AMICA1 
               
               
                 2, mRNA [NM_153206] 
                   
               
               
                 syntaxin 10 (STX10), mRNA [NM_003765] 
                 STX10 
               
               
                 spleen tyrosine kinase (SYK), transcript variant 1, mRNA [NM_003177] 
                 SYK 
               
               
                 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (AGAP2), 
                 AGAP2 
               
               
                 transcript variant 1, mRNA [NM_001122772] 
                   
               
               
                 acyl-CoA synthetase long-chain family member 1 (ACSL1), mRNA [NM_001995] 
                 ACSL1 
               
               
                 replication factor C (activator 1) 4, 37 kDa (RFC4), transcript variant 1, mRNA 
                 RFC4 
               
               
                 [NM_002916] 
                   
               
               
                 immunoglobulin superfamily, member 6 (IGSF6), mRNA [NM_005849] 
                 IGSF6 
               
               
                 colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte- 
                 CSF2RA 
               
               
                 macrophage) (CSF2RA), transcript variant 6, mRNA [NM_172249] 
                   
               
               
                 death-associated protein kinase 1 (DAPK1), mRNA [NM_004938] 
                 DAPK1 
               
               
                 complement component (3d/Epstein Barr virus) receptor 2 (CR2), transcript 
                 CR2 
               
               
                 variant 1, mRNA [NM_001006658] 
                   
               
               
                 caspase recruitment domain family, member 9 (CARD9), transcript variant 2, 
                 CARD9 
               
               
                 mRNA [NM_052814] 
                   
               
               
                 zinc finger protein 790 (ZNF790), transcript variant 4, mRNA [NM_001242802]  
                 ZNF790 
               
               
                 neutrophil cytosolic factor 2 (NCF2), transcript variant 1, mRNA [NM_000433] 
                 NCF2 
               
               
                 Morf4 family associated protein 1-like 1 (MRFAP1L1), mRNA [NM_203462] 
                 MRFAP1L1 
               
               
                 aurora kinase B (AURKB), mRNA [NM_004217] 
                 AURKB 
               
               
                 alanyl (membrane) aminopeptidase (ANPEP), mRNA [NM_001150] 
                 ANPEP 
               
               
                 lymphotoxin beta receptor (TNFR superfamily, member 3) (LTBR), mRNA 
                 LTBR 
               
               
                 [NM_002342] 
                   
               
               
                 solute carrier family 15, member 3 (SLC15A3), transcript variant 1, mRNA 
                 SLC15A3 
               
               
                 [NM_016582] 
                   
               
               
                 guanine nucleotide binding protein (G protein), beta polypeptide 4 (GNB4), 
                 GNB4 
               
               
                 mRNA [NM_021629] 
                   
               
               
                 protein kinase, cAMP-dependent, regulatory, type I, beta (PRKAR1B), transcript 
                 PRKAR1B 
               
               
                 variant 1, mRNA [NM_001164761] 
                   
               
               
                 multiple EGF-like-domains 9 (MEGF9), mRNA [NM_001080497] 
                 MEGF9 
               
               
                 ATP-binding cassette, sub-family D (ALD), member 1 (ABCD1), mRNA 
                 ABCD1 
               
               
                 [NM_000033] 
                   
               
               
                 S100 calcium binding protein All (S100A11), mRNA [NM_005620] 
                 S100A11 
               
               
                 platelet derived growth factor C (PDGFC), transcript variant 1, mRNA 
                 PDGFC 
               
               
                 [NM_016205] 
                   
               
               
                 ATPase family, AAA domain containing 1 (ATAD1), mRNA [NM_032810] 
                 ATAD1 
               
               
                 sialic acid binding Ig-like lectin 1, sialoadhesin (SIGLEC1), mRNA [NM_023068] 
                 SIGLEC1 
               
               
                 tumor necrosis factor (ligand) superfamily, member 13 (TNFSF13), transcript 
                 TNFSF13 
               
               
                 variant gamma, mRNA [NM_172088] 
                   
               
               
                 CD302 molecule (CD302), transcript variant 1, mRNA [NM_014880] 
                 CD302 
               
               
                 Rho guanine nucleotide exchange factor (GEF) 10-like (ARHGEF10L), transcript 
                 ARHGEF10L 
               
               
                 variant 1, mRNA [NM_018125] 
                   
               
               
                 hematopoietically expressed homeobox (HHEX), mRNA [NM_002729] 
                 HHEX 
               
               
                 keratin 23 (histone deacetylase inducible) (KRT23), mRNA [NM_015515] 
                 KRT23 
               
               
                 establishment of cohesion 1 homolog 2 ( S. cerevisiae ) (ESCO2), mRNA 
                 ESCO2 
               
               
                 [NM_001017420] 
                   
               
               
                 retinoic acid receptor responder (tazarotene induced) 3 (RARRES3), mRNA 
                 RARRES3 
               
               
                 [NM_004585] 
                   
               
               
                 neutral cholesterol ester hydrolase 1 (NCEH1), transcript variant 2, mRNA 
                 NCEH1 
               
               
                 [NM_020792] 
                   
               
               
                 anoctamin 10 (ANO10), transcript variant 2, mRNA [NM_001204831] 
                 ANO10 
               
               
                 RAB32, member RAS oncogene family (RAB32), mRNA [NM_006834] 
                 RAB32 
               
               
                 Fc fragment of IgG, receptor, transporter, alpha (FCGRT), transcript variant 2, 
                 FCGRT 
               
               
                 mRNA [NM_004107] 
                   
               
               
                 chromosome 3 open reading frame 26 (C3orf26), transcript variant 1, mRNA 
                 C3orf26 
               
               
                 [NM_032359] 
                   
               
               
                 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 (ARAP3), mRNA 
                 ARAP3 
               
               
                 [NM_022481] 
                   
               
               
                 thromboxane A synthase 1 (platelet) (TBXAS1), transcript variant 5, mRNA 
                 TBXAS1 
               
               
                 [NM_001166254] 
                   
               
               
                 formyl peptide receptor 2 (FPR2), transcript variant 1, mRNA [NM_001462] 
                 FPR2 
               
               
                 angiotensin II receptor-associated protein (AGTRAP), transcript variant 4, 
                 AGTRAP 
               
               
                 mRNA [NM_001040196] 
                   
               
               
                 FYVE, RhoGEF and PH domain containing 4 (FGD4), mRNA [NM_139241] 
                 FGD4 
               
               
                 chemokine (C-C motif) receptor 7 (CCR7), mRNA [NM_001838] 
                 CCR7 
               
               
                 colony stimulating factor 1 receptor (CSF1R), mRNA [NM_005211] 
                 CSF1R 
               
               
                 tocopherol (alpha) transfer protein-like (TTPAL), transcript variant 1, mRNA 
                 TTPAL 
               
               
                 [NM_024331] 
                   
               
               
                 toll-like receptor 7 (TLR7), mRNA [NM_016562] 
                 TLR7 
               
               
                 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), 
                 LILRA5 
               
               
                 member 5 (LILRA5), transcript variant 3, mRNA [NM_181879] 
                   
               
               
                 potassium inwardly-rectifying channel, subfamily J, member 15 (KCNJ15), 
                 KCNJ15 
               
               
                 transcript variant 1, mRNA [NM_170736] 
                   
               
               
                 HD domain containing 2 (HDDC2), mRNA [NM_016063] 
                 HDDC2 
               
               
                 centromere protein E, 312 kDa (CENPE), mRNA [NM_001813] 
                 CENPE 
               
               
                 DEP domain containing 1B (DEPDC1B), transcript variant 1, mRNA 
                 DEPDC1B 
               
               
                 [NM_018369] 
                   
               
               
                 coagulation factor XIII, A1 polypeptide (F13A1), mRNA [NM_000129] 
                 F13A1 
               
               
                 transketolase (TKT), transcript variant 1, mRNA [NM_001064] 
                 TKT 
               
               
                 sialic acid acetylesterase (SIAE), transcript variant 1, mRNA [NM_170601] 
                 SIAE 
               
               
                 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 
                 PLA2G7 
               
               
                 (PLA2G7), transcript variant 1, mRNA [NM_005084] 
                   
               
               
                 hydrogen voltage-gated channel 1 (HVCN1), transcript variant 1, mRNA 
                 HVCN1 
               
               
                 [NM_001040107] 
                   
               
               
                 vimentin (VIM), mRNA [NM_003380] 
                 VIM 
               
               
                 SET and MYND domain containing 3 (SMYD3), transcript variant 2, mRNA 
                 SMYD3 
               
               
                 [NM_022743] 
                   
               
               
                 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM 
                 LILRB1 
               
               
                 domains), member 1 (LILRB1), transcript variant 1, mRNA [NM_006669] 
                   
               
               
                 solute carrier family 46, member 2 (SLC46A2), mRNA [NM_033051] 
                 SLC46A2 
               
               
                 cell division cycle 25 homolog A ( S. pombe ) (CDC25A), transcript variant 1, 
                 CDC25A 
               
               
                 mRNA [NM_001789] 
                   
               
               
                 Morf4 family associated protein 1-like 1 pseudogene (LOC93622), non-coding 
                 LOC93622 
               
               
                 RNA [NR_015433] 
                   
               
               
                 transcription factor EC (TFEC), transcript variant 1, mRNA [NM_012252] 
                 TFEC 
               
               
                 bactericidal/permeability-increasing protein (BPI), mRNA [NM_001725] 
                 BPI 
               
               
                 macrophage receptor with collagenous structure (MARCO), mRNA 
                 MARCO 
               
               
                 [NM_006770] 
                   
               
               
                 phosphotyrosine interaction domain containing 1 (PID1), transcript variant 1, 
                 PID1 
               
               
                 mRNA [NM_017933] 
                   
               
               
                 IKAROS family zinc finger 1 (Ikaros) (IKZF1), transcript variant 1, mRNA 
                 IKZF1 
               
               
                 [NM_006060] 
                   
               
               
                 G patch domain containing 4 [Source: HGNC Symbol;Acc: 25982] 
                 GPATCH4 
               
               
                 [ENST00000334588] 
                   
               
               
                 butyrophilin, subfamily 3, member A2 (BTN3A2), transcript variant 3, mRNA 
                 BTN3A2 
               
               
                 [NM_001197247] 
                   
               
               
                 lymphocyte antigen 9 (LY9), transcript variant 2, mRNA [NM_001033667] 
                 LY9 
               
               
                 tetratricopeptide repeat domain 7A (TTC7A), mRNA [NM_020458] 
                 TTC7A 
               
               
                 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), 
                 SERPINA1 
               
               
                 member 1 [Source: HGNC Symbol;Acc: 8941] [ENST00000402629] 
                   
               
               
                 AKT interacting protein (AKTIP), transcript variant 1, mRNA [NM_001012398] 
                 AKTIP 
               
               
                 sperm associated antigen 5 (SPAG5), mRNA [NM_006461] 
                 SPAG5 
               
               
                 interleukin 1 receptor antagonist (IL1RN), transcript variant 4, mRNA 
                 IL1RN 
               
               
                 [NM_173843] 
                   
               
               
                 ATG7 autophagy related 7 homolog ( S. cerevisiae ) (ATG7), transcript variant 1, 
                 ATG7 
               
               
                 mRNA [NM_006395] 
                   
               
               
                 prosaposin (PSAP), transcript variant 2, mRNA [NM_001042465] 
                 PSAP 
               
               
                 phosphogluconate dehydrogenase (PGD), mRNA [NM_002631] 
                 PGD 
               
               
                 complement factor properdin (CFP), transcript variant 1, mRNA [NM_002621]  
                 CFP 
               
               
                 hexokinase 3 (white cell) (HK3), nuclear gene encoding mitochondrial protein, 
                 HK3 
               
               
                 mRNA [NM_002115] 
                   
               
               
                 sialic acid binding Ig-like lectin 7 (SIGLEC7), transcript variant 1, mRNA 
                 SIGLEC7 
               
               
                 [NM_014385] 
                   
               
               
                 granulin (GRN), mRNA [NM_002087] 
                 GRN 
               
               
                 quiescin Q6 sulfhydryl oxidase 1 (QSOX1), transcript variant 2, mRNA 
                 QSOX1 
               
               
                 [NM_001004128] 
                   
               
               
                 ubiquitin-conjugating enzyme E2D 1 (UBE2D1), transcript variant 1, mRNA 
                 UBE2D1 
               
               
                 [NM_003338] 
                   
               
               
                 heme binding protein 2 (HEBP2), mRNA [NM_014320] 
                 HEBP2 
               
               
                 BCL2-related protein A1 (BCL2A1), transcript variant 1, mRNA [NM_004049] 
                 BCL2A1 
               
               
                 branched chain ketoacid dehydrogenase kinase (BCKDK), nuclear gene 
                 BCKDK 
               
               
                 encoding mitochondrial protein, transcript variant 1, mRNA [NM_005881] 
                   
               
               
                 membrane bound O-acyltransferase domain containing 7 (MBOAT7), transcript 
                 MBOAT7 
               
               
                 variant 4, mRNA [NM_001146082] 
                   
               
               
                 arachidonate 5-lipoxygenase (ALOX5), mRNA [NM_000698] 
                 ALOX5 
               
               
                 NLR family, CARD domain containing 4 (NLRC4), transcript variant 1, mRNA 
                 NLRC4 
               
               
                 [NM_021209] 
                   
               
               
                 phospholipase D family, member 3 (PLD3), transcript variant 2, mRNA 
                 PLD3 
               
               
                 [NM_012268] 
                   
               
               
                 HEN1 methyltransferase homolog 1 ( Arabidopsis ) (HENMT1), transcript variant 
                 HENMT1 
               
               
                 1, mRNA [NM_144584] 
                   
               
               
                 chromosome 20 open reading frame 194 (C20orf194), mRNA [NM_001009984] 
                 C20orf194 
               
               
                 nucleotide-binding oligomerization domain containing 2 (NOD2), mRNA 
                 NOD2 
               
               
                 [NM_022162] 
                   
               
               
                 glutaminyl-peptide cyclotransferase (QPCT), mRNA [NM_012413] 
                 QPCT 
               
               
                 minichromosome maintenance complex component 7 (MCM7), transcript 
                 MCM7 
               
               
                 variant 2, mRNA [NM_182776] 
                   
               
               
                 protein tyrosine phosphatase, receptor type, K (PTPRK), transcript variant 2, 
                 PTPRK 
               
               
                 mRNA [NM_002844] 
                   
               
               
                 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 
                 RNASE2 
               
               
                 (RNASE2), mRNA [NM_002934] 
                   
               
               
                 Niemann-Pick disease, type C2 (NPC2), mRNA [NM_006432] 
                 NPC2 
               
               
                 CD9 molecule (CD9), mRNA [NM_001769] 
                 CD9 
               
               
                 brain protein I3 (BRI3), transcript variant 1, mRNA [NM_015379] 
                 BRI3 
               
               
                 transmembrane protein 55A (TMEM55A), mRNA [NM_018710] 
                 TMEM55A 
               
               
                 macrophage expressed 1 (MPEG1), mRNA [NM_001039396] 
                 MPEG1 
               
               
                 two pore segment channel 1 (TPCN1), transcript variant 1, mRNA 
                 TPCN1 
               
               
                 [NM_001143819] 
                   
               
               
                 glucosidase, alpha; acid (GAA), transcript variant 1, mRNA [NM_000152] 
                 GAA 
               
               
                 dicer 1, ribonuclease type III (DICER1), transcript variant 3, mRNA 
                 DICER1 
               
               
                 [NM_001195573] 
                   
               
               
                 tweety homolog 3 ( Drosophila ) (TTYH3), mRNA [NM_025250] 
                 TTYH3 
               
               
                 ring finger protein 130 (RNF130), mRNA [NM_018434] 
                 RNF130 
               
               
                 sterile alpha motif domain containing 13 (SAMD13), transcript variant 1, mRNA 
                 SAMD13 
               
               
                 [NM_001010971] 
                   
               
               
                 solute carrier organic anion transporter family, member 4C1 (SLCO4C1), mRNA 
                 SLCO4C1 
               
               
                 [NM_180991] 
                   
               
               
                 CD14 molecule (CD14), transcript variant 3, mRNA [NM_001174104] 
                 CD14 
               
               
                 tubulin tyrosine ligase-like family, member 4 (TTLL4), mRNA [NM_014640] 
                 TTLL4 
               
               
                 frizzled family receptor 5 (FZD5), mRNA [NM_003468] 
                 FZD5 
               
               
                 mitogen-activated protein kinase kinase kinase 3 (MAP3K3), transcript variant 
                 MAP3K3 
               
               
                 1, mRNA [NM_203351] 
                   
               
               
                 cathepsin B (CTSB), transcript variant 2, mRNA [NM_147780] 
                 CTSB 
               
               
                 structural maintenance of chromosomes 2 (SMC2), transcript variant 1, mRNA 
                 SMC2 
               
               
                 [NM_001042550] 
                   
               
               
                 transmembrane protein 51 (TMEM51), transcript variant 1, mRNA 
                 TMEM51 
               
               
                 [NM_001136216] 
                   
               
               
                 interleukin 21 receptor (IL21R), transcript variant 2, mRNA [NM_181078] 
                 IL21R 
               
               
                 vanin 2 (VNN2), transcript variant 1, mRNA [NM_004665] 
                 VNN2 
               
               
                 bone marrow stromal cell antigen 1 (BST1), mRNA [NM_004334] 
                 BST1 
               
               
                 non-SMC condensin II complex, subunit G2 (NCAPG2), mRNA [NM_017760] 
                 NCAPG2 
               
               
                 glutathione peroxidase 1 (GPX1), transcript variant 2, mRNA [NM_201397] 
                 GPX1 
               
               
                 potassium inwardly-rectifying channel, subfamily J, member 2 (KCNJ2), mRNA 
                 KCNJ2 
               
               
                 [NM_000891] 
                   
               
               
                 feline sarcoma oncogene (FES), transcript variant 1, mRNA [NM_002005] 
                 FES 
               
               
                 dipeptidyl-peptidase 4 (DPP4), mRNA [NM_001935] 
                 DPP4 
               
               
                 butyrophilin, subfamily 3, member A1 (BTN3A1), transcript variant 1, mRNA 
                 BTN3A1 
               
               
                 [NM_007048] 
                   
               
               
                 azurocidin 1 (AZU1), mRNA [NM_001700] 
                 AZU1 
               
               
                 geminin, DNA replication inhibitor (GMNN), transcript variant 1, mRNA 
                 GMNN 
               
               
                 [NM_015895] 
                   
               
               
                 gelsolin (GSN), transcript variant 4, mRNA [NM_001127663] 
                 GSN 
               
               
                 cytoplasmic polyadenylation element binding protein 4 (CPEB4), mRNA 
                 CPEB4 
               
               
                 [NM_030627] 
                   
               
               
                 interleukin 12 receptor, beta 2 (IL12RB2), mRNA [NM_001559] 
                 IL12RB2 
               
               
                 allograft inflammatory factor 1 (AIF1), transcript variant 2, mRNA [NM_004847] 
                 AIF1 
               
               
                 apoptosis-inducing, TAF9-like domain 1 (APITD1), transcript variant A, mRNA 
                 APITD1 
               
               
                 [NM_199294] 
                   
               
               
                 Bruton agammaglobulinemia tyrosine kinase (BTK), mRNA [NM_000061] 
                 BTK 
               
               
                 nurim (nuclear envelope membrane protein) (NRM), mRNA [NM_007243] 
                 NRM 
               
               
                 membrane-spanning 4-domains, subfamily A, member 1 (M54A1), transcript 
                 MS4A1 
               
               
                 variant 1, mRNA [NM_152866] 
                   
               
               
                 major facilitator superfamily domain containing 1 (MFSD1), transcript variant 1, 
                 MFSD1 
               
               
                 mRNA [NM_022736] 
                   
               
               
                 REX4, RNA exonuclease 4 homolog ( S. cerevisiae ) (REXO4), mRNA 
                 REXO4 
               
               
                 [NM_020385] 
                   
               
               
                 sialic acid binding Ig-like lectin 5 (SIGLEC5), mRNA [NM_003830] 
                 SIGLEC5 
               
               
                 glutamate-rich WD repeat containing 1 (GRWD1), mRNA [NM_031485] 
                 GRWD1 
               
               
                 transmembrane protein 176A (TMEM176A), mRNA [NM_018487] 
                 TMEM176A 
               
               
                 chemokine (C-C motif) receptor-like 2 (CCRL2), transcript variant 1, mRNA 
                 CCRL2 
               
               
                 [NM_003965] 
                   
               
               
                 early B-cell factor 1 (EBF1), mRNA [NM_024007] 
                 EBF1 
               
               
                 bromodomain and WD repeat domain containing 3 (BRWD3), mRNA 
                 BRWD3 
               
               
                 [NM_153252] 
                   
               
               
                 Zwilch, kinetochore associated, homolog ( Drosophila ) (ZWILCH), transcript 
                 ZWILCH 
               
               
                 variant 1, mRNA [NM_017975] 
                   
               
               
                 cyclin-dependent kinase 2 (CDK2), transcript variant 1, mRNA [NM_001798] 
                 CDK2 
               
               
                 kelch-like 18 ( Drosophila ) (KLHL18), mRNA [NM_025010] 
                 KLHL18 
               
               
                 zinc finger protein 367 (ZNF367), mRNA [NM_153695] 
                 ZNF367 
               
               
                 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, 
                 NFKBIA 
               
               
                 alpha (NFKBIA), mRNA [NM_020529] 
                   
               
               
                 dihydropyrimidine dehydrogenase (DPYD), transcript variant 2, mRNA 
                 DPYD 
               
               
                 [NM_001160301] 
                   
               
               
                 zinc finger protein 36, C3H type, homolog (mouse) (ZFP36), mRNA 
                 ZFP36 
               
               
                 [NM_003407] 
                   
               
               
                 coagulation factor V (proaccelerin, labile factor) (F5), mRNA [NM_000130] 
                 F5 
               
               
                 SMEK homolog 2, suppressor of mek1 (Dictyostelium) (SMEK2), transcript 
                 SMEK2 
               
               
                 variant 2, mRNA [NM_020463] 
                   
               
               
                 GINS complex subunit 4 (Sld5 homolog) (GINS4), mRNA [NM_032336] 
                 GINS4 
               
               
                 CD22 molecule (CD22), transcript variant 1, mRNA [NM_001771] 
                 CD22 
               
               
                 mRNA for very long-chain acyl-CoA synthetase homologue 3 (VLCS-3 gene). 
                 SLC27A3 
               
               
                 [AJ577572] 
                   
               
               
                 cell division cycle 7 homolog ( S. cerevisiae ) (CDC7), transcript variant 1, mRNA 
                 CDC7 
               
               
                 [NM_003503] 
                   
               
               
                 grancalcin, EF-hand calcium binding protein (GCA), mRNA [NM_012198] 
                 GCA 
               
               
                 signal-regulatory protein beta 1 (SIRPB1), transcript variant 3, mRNA 
                 SIRPB1 
               
               
                 [NM_001135844] 
                   
               
               
                 CDC42 binding protein kinase beta (DMPK-like) (CDC42BPB), mRNA 
                 CDC42BPB 
               
               
                 [NM_006035] 
                   
               
               
                 spinster homolog 1 ( Drosophila ) (SPNS1), transcript variant 1, mRNA 
                 SPNS1 
               
               
                 [NM_032038] 
                   
               
               
                 tetraspanin 15 (TSPAN15), mRNA [NM_012339] 
                 TSPAN15 
               
               
                 cystatin C (CST3), mRNA [NM_000099] 
                 CST3 
               
               
                 plexin B2 (PLXNB2), mRNA [NM_012401] 
                 PLXNB2 
               
               
                 Ras association (RalGDS/AF-6) domain family member 4 (RASSF4), mRNA 
                 RASSF4 
               
               
                 [NM_032023] 
                   
               
               
                 PREDICTED: peptidyl-prolyl cis-trans isomerase A-like (LOC100288602), mRNA 
                 LOC100288602 
               
               
                 [XM_003403504] 
                   
               
               
                 protein kinase (cAMP-dependent, catalytic) inhibitor alpha (PKIA), transcript 
                 PKIA 
               
               
                 variant 1, mRNA [NM_006823] 
                   
               
               
                 chromosome 9 open reading frame 7 (C9orf7), transcript variant 3, mRNA 
                 C9orf7 
               
               
                 [NM_001242369] 
                   
               
               
                 toll-like receptor 1 (TLR1), mRNA [NM_003263] 
                 TLR1 
               
               
                 centrosomal protein 76 kDa (CEP76), mRNA [NM_024899] 
                 CEP76 
               
               
                 protein kinase C, delta (PRKCD), transcript variant 1, mRNA [NM_006254] 
                 PRKCD 
               
               
                 CD1a molecule (CD1A), mRNA [NM_001763] 
                 CD1A 
               
               
                 plectin (PLEC), transcript variant 6, mRNA [NM_201380] 
                 PLEC 
               
               
                 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), 
                 LILRA6 
               
               
                 member 6 (LILRA6), mRNA [NM_024318] 
                   
               
               
                 RCC1 domain containing 1 (RCCD1), transcript variant 1, mRNA [NM_033544] 
                 RCCD1 
               
               
                 dihydrofolate reductase (DHFR), mRNA [NM_000791] 
                 DHFR 
               
               
                 solute carrier family 31 (copper transporters), member 2 (SLC31A2), mRNA 
                 SLC31A2 
               
               
                 [NM_001860] 
                   
               
               
                 protein arginine methyltransferase 1 (PRMT1), transcript variant 1, mRNA 
                 PRMT1 
               
               
                 [NM_001536] 
                   
               
               
                 NEAT activating protein with ITAM motif 1 (NFAM1), mRNA [NM_145912] 
                 NFAM1 
               
               
                 adducin 3 (gamma) (ADD3), transcript variant 1, mRNA [NM_016824] 
                 ADD3 
               
               
                 acyloxyacyl hydrolase (neutrophil) (AOAH), transcript variant 1, mRNA 
                 AOAH 
               
               
                 [NM_001637] 
                   
               
               
                 TYRO protein tyrosine kinase binding protein (TYROBP), transcript variant 1, 
                 TYROBP 
               
               
                 mRNA [NM_003332] 
                   
               
               
                 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), 
                 LILRA2 
               
               
                 member 2 (LILRA2), transcript variant 2, mRNA [NM_006866] 
                   
               
               
                 Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog (FGR), 
                 FGR 
               
               
                 transcript variant 2, mRNA [NM_001042747] 
                   
               
               
                 neutrophil cytosolic factor 1 (NCF1), mRNA [NM_000265] 
                 NCF1 
               
               
                 Rac GTPase activating protein 1 (RACGAP1), transcript variant 1, mRNA 
                 RACGAP1 
               
               
                 [NM_013277] 
                   
               
               
                 shugoshin-like 2 ( S. pombe ) (SGOL2), transcript variant 1, mRNA [NM_152524]  
                 SGOL2 
               
               
                 G protein-coupled receptor 84 (GPR84), mRNA [NM_020370] 
                 GPR84 
               
               
                 Fc receptor-like 1 (FCRL1), transcript variant 2, mRNA [NM_001159397] 
                 FCRL1 
               
               
                 ninjurin 2 (NINJ2), mRNA [NM_016533] 
                 NINJ2 
               
               
                 membrane protein, palmitoylated 1, 55 kDa (MPP1), transcript variant 3, mRNA 
                 MPP1 
               
               
                 [NM_001166461] 
                   
               
               
                 formyl peptide receptor 1 (FPR1), transcript variant 2, mRNA [NM_002029] 
                 FPR1 
               
               
                 phosphatidylinositol transfer protein, beta (PITPNB), mRNA [NM_012399] 
                 PITPNB 
               
               
                 RAD21 homolog ( S. pombe ) (RAD21), mRNA [NM_006265] 
                 RAD21 
               
               
                 glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 
                 GRINA 
               
               
                 (glutamate binding) (GRINA), transcript variant 1, mRNA [NM_000837] 
                   
               
               
                 histone deacetylase 8 (HDAC8), transcript variant 1, mRNA [NM_018486] 
                 HDAC8 
               
               
                 guanine nucleotide binding protein (G protein), gamma 10 (GNG10), transcript 
                 GNG10 
               
               
                 variant 1, mRNA [NM_001017998] 
                   
               
               
                 CD19 molecule (CD19), transcript variant 2, mRNA [NM_001770] 
                 CD19 
               
               
                 elastin microfibril interfacer 2 (EMILIN2), mRNA [NM_032048] 
                 EMILIN2 
               
               
                 chemokine (C-C motif) receptor 2 (CCR2), transcript variant A, mRNA 
                 CCR2 
               
               
                 [NM_001123041] 
                   
               
               
                 mitochondrial translation optimization 1 homolog ( S. cerevisiae ) (MTO1), 
                 MTO1 
               
               
                 nuclear gene encoding mitochondrial protein, transcript variant 2, mRNA 
                   
               
               
                 [NM_012123] 
                   
               
               
                 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM 
                 LILRB2 
               
               
                 domains), member 2 (LILRB2), transcript variant 1, mRNA [NM_005874] 
                   
               
               
                 docking protein 3 (DOK3), transcript variant 2, mRNA [NM_001144875] 
                 DOK3 
               
               
                 actinin, alpha 1 (ACTN1), transcript variant 2, mRNA [NM_001102] 
                 ACTN1 
               
               
                 antigen identified by monoclonal antibody Ki-67 (MKI67), transcript variant 1, 
                 MKI67 
               
               
                 mRNA [NM_002417] 
                   
               
               
                 Ran GTPase activating protein 1 (RANGAP1), mRNA [NM_002883] 
                 RANGAP1 
               
               
                 neural proliferation, differentiation and control, 1 (NPDC1), mRNA 
                 NPDC1 
               
               
                 [NM_015392] 
                   
               
               
                 spleen focus forming virus (SFFV) proviral integration oncogene soil (SPI1), 
                 SPI1 
               
               
                 transcript variant 1, mRNA [NM_001080547] 
                   
               
               
                 neural precursor cell expressed, developmentally down-regulated 1 (NEDD1), 
                 NEDD1 
               
               
                 transcript variant 2, mRNA [NM_152905] 
                   
               
               
                 primase, DNA, polypeptide 2 (58 kDa) (PRIM2), mRNA [NM_000947] 
                 PRIM2 
               
               
                 hemopoietic cell kinase (HCK), transcript variant 1, mRNA [NM_002110] 
                 HCK 
               
               
                 primase, DNA, polypeptide 1 (49 kDa) (PRIM1), mRNA [NM_000946] 
                 PRIM1 
               
               
                 ficolin (collagen/fibrinogen domain containing) 1 (FCN1), mRNA [NM_002003] 
                 FCN1 
               
               
                 timeless homolog ( Drosophila ) (TIMELESS), mRNA [NM_003920] 
                 TIMELESS 
               
               
                 dermatan sulfate epimerase (DSE), transcript variant 1, mRNA [NM_013352] 
                 DSE 
               
               
                 SUM01 activating enzyme subunit 1 (SAE1), transcript variant 1, mRNA 
                 SAE1 
               
               
                 [NM_005500] 
                   
               
               
                 S100 calcium binding protein A8 (5100A8), mRNA [NM_002964] 
                 S100A8 
               
               
                 tubulin, gamma 1 (TUBG1), mRNA [NM_001070] 
                 TUBG1 
               
               
                 ATP synthase mitochondrial F1 complex assembly factor 2 (ATPAF2), nuclear 
                 ATPAF2 
               
               
                 gene encoding mitochondrial protein, mRNA [NM_145691] 
                   
               
               
                 zinc finger protein 131 (ZNF131), mRNA [NM_003432] 
                 ZNF131 
               
               
                 replication protein A3, 14 kDa (RPA3), mRNA [NM_002947] 
                 RPA3 
               
               
                 cDNA FLJ42230 fis, clone THYMU3000036. [AK124224] 
                 SIRPG 
               
               
                 CDC28 protein kinase regulatory subunit 1B (CKS1B), transcript variant 1, mRNA 
                 CKS1B 
               
               
                 [NM_001826] 
                   
               
               
                 guanine nucleotide binding protein (G protein), q polypeptide (GNAQ), mRNA 
                 GNAQ 
               
               
                 [NM_002072] 
                   
               
               
                 KIAA0125 (KIAA0125), non-coding RNA [NR_026800] 
                 KIAA0125 
               
               
                 S100 calcium binding protein A9 (S100A9), mRNA [NM_002965] 
                 S100A9 
               
               
                 SP140 nuclear body protein (SP140), transcript variant 1, mRNA [NM_007237] 
                 SP140 
               
               
                 cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) (CDKN2A), 
                 CDKN2A 
               
               
                 transcript variant 3, mRNA [NM_058197] 
                   
               
               
                 major histocompatibility complex, class II, DQ beta 1 (HLA-DQB1), transcript 
                 HLA-DQB1 
               
               
                 variant 2, mRNA [NM_001243961] 
                   
               
               
                 B lymphoid tyrosine kinase (BLK), mRNA [NM_001715] 
                 BLK 
               
               
                 protein kinase, membrane associated tyrosine/threonine 1 (PKMYT1), 
                 PKMYT1 
               
               
                 transcript variant 2, mRNA [NM_182687] 
                   
               
               
                 trafficking protein particle complex 5 (TRAPPC5), transcript variant 1, mRNA 
                 TRAPPC5 
               
               
                 [NM_174894] 
                   
               
               
                 linker for activation of T cells family, member 2 (LAT2), transcript variant 1, 
                 LAT2 
               
               
                 mRNA [NM_032464] 
                   
               
               
                 transmembrane protein 176B (TMEM176B), transcript variant 1, mRNA 
                 TMEM176B 
               
               
                 [NM_014020] 
                   
               
               
                 zyxin (ZYX), transcript variant 1, mRNA [NM_003461] 
                 ZYX 
               
               
                 interferon, gamma-inducible protein 30 (IFI30), mRNA [NM_006332] 
                 IFI30 
               
               
                 cathepsin H (CTSH), mRNA [NM_004390] 
                 CTSH 
               
               
                 tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B), transcript 
                 TNFSF13B 
               
               
                 variant 1, mRNA [NM_006573] 
                   
               
               
                 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) (RDH14), mRNA [NM_020905]  
                 RDH14 
               
               
                 guanylate binding protein 3 (GBP3), mRNA [NM_018284] 
                 GBP3 
               
               
                 centrosomal protein 72 kDa (CEP72), mRNA [NM_018140] 
                 CEP72 
               
               
                 extracellular matrix protein 1 (ECM1), transcript variant 1, mRNA [NM_004425] 
                 ECM1 
               
               
                 uridine monophosphate synthetase (UMPS), transcript variant 1, mRNA 
                 UMPS 
               
               
                 [NM_000373] 
                   
               
               
                 purinergic receptor P2X, ligand-gated ion channel, 5 (P2RX5), transcript variant 
                 P2RX5 
               
               
                 2, mRNA [NM_175080] 
                   
               
               
                 catenin, beta interacting protein 1 (CTNNBIP1), transcript variant 1, mRNA 
                 CTNNBIP1 
               
               
                 [NM_020248] 
                   
               
               
                 structural maintenance of chromosomes 4 (SMC4), transcript variant 1, mRNA 
                 SMC4 
               
               
                 [NM_005496] 
                   
               
               
                 H2A histone family, member J (H2AFJ), transcript variant 1, mRNA 
                 H2AFJ 
               
               
                 [NM_177925] 
                   
               
               
                 integrin, alpha M (complement component 3 receptor 3 subunit) (ITGAM), 
                 ITGAM 
               
               
                 transcript variant 2, mRNA [NM_000632] 
                   
               
               
                 ras homolog gene family, member U (RHOU), transcript variant 1, mRNA 
                 RHOU 
               
               
                 [NM_021205] 
                   
               
               
                 leucine rich repeat containing 8 family, member A (LRRC8A), transcript variant 
                 LRRC8A 
               
               
                 2, mRNA [NM_019594] 
                   
               
               
                 family with sequence similarity 105, member A (FAM105A), mRNA 
                 FAM105A 
               
               
                 [NM_019018] 
                   
               
               
                 family with sequence similarity 185, member A (FAM185A), transcript variant 1, 
                 FAM185A 
               
               
                 mRNA [NM_001145268] 
                   
               
               
                 replication factor C (activator 1) 5, 36.5 kDa (RFC5), transcript variant 2, mRNA 
                 RFC5 
               
               
                 [NM_181578] 
                   
               
               
                 tumor necrosis factor (ligand) superfamily, member 14 (TNFSF14), transcript 
                 TNFSF14 
               
               
                 variant 1, mRNA [NM_003807] 
                   
               
               
                 chemokine (C-X3-C motif) receptor 1 (CX3CR1), transcript variant 4, mRNA 
                 CX3CR1 
               
               
                 [NM_001337] 
                   
               
               
                 PYD and CARD domain containing (PYCARD), transcript variant 1, mRNA 
                 PYCARD 
               
               
                 [NM_013258] 
                   
               
               
                 transmembrane protein 154 (TMEM154), mRNA [NM_152680] 
                 TMEM154 
               
               
                 shugoshin-like 1 ( S. pombe ) (SGOL1), transcript variant A2, mRNA 
                 SGOL1 
               
               
                 [NM_001012410] 
                   
               
               
                 poly (ADP-ribose) polymerase family, member 9 (PARP9), transcript variant 1, 
                 PARP9 
               
               
                 mRNA [NM_031458] 
                   
               
               
                 cathepsin D (CTSD), mRNA [NM_001909] 
                 CTSD 
               
               
                 dual specificity phosphatase 22 (DUSP22), mRNA [NM_020185] 
                 DUSP22 
               
               
                 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) (PTPN22), 
                 PTPN22 
               
               
                 transcript variant 2, mRNA [NM_012411] 
                   
               
               
                 1-acylglycerol-3-phosphate O-acyltransferase 9 (AGPAT9), mRNA [NM_032717] 
                 AGPAT9 
               
               
                 C-type lectin domain family 2, member D (CLEC2D), transcript variant 2, mRNA 
                 CLEC2D 
               
               
                 [NM_001004419] 
                   
               
               
                 cyclin-dependent kinase 14 (CDK14), mRNA [NM_012395] 
                 CDK14 
               
               
                 kinetochore associated 1 (KNTC1), mRNA [NM_014708] 
                 KNTC1 
               
               
                 phosphorylase kinase, beta (PHKB), transcript variant 2, mRNA 
                 PHKB 
               
               
                 [NM_001031835] 
                   
               
               
                 extra spindle pole bodies homolog 1 ( S. cerevisiae ) (ESPL1), mRNA 
                 ESPL1 
               
               
                 [NM_012291] 
                   
               
               
                 heparan-alpha-glucosaminide N-acetyltransferase (HGSNAT), mRNA 
                 HGSNAT 
               
               
                 [NM_152419] 
                   
               
               
                 ERI1 exoribonuclease family member 2 (ERI2), transcript variant 2, mRNA 
                 ERI2 
               
               
                 [NM_080663] 
                   
               
               
                 endoglin (ENG), transcript variant 2, mRNA [NM_000118] 
                 ENG 
               
               
                 polymerase (DNA directed), alpha 1, catalytic subunit (POLA1), mRNA 
                 POLA1 
               
               
                 [NM_016937] 
                   
               
               
                 adaptor-related protein complex 1, sigma 2 subunit (AP1S2), mRNA 
                 AP1S2 
               
               
                 [NM_003916] 
                   
               
               
                 ADAM metallopeptidase domain 12 (ADAM12), transcript variant 2, mRNA 
                 ADAM12 
               
               
                 [NM_021641] 
                   
               
               
                 Fc fragment of IgG, high affinity 1b, receptor (CD64) (FCGR1B), transcript variant 
                 FCGR1B 
               
               
                 3, mRNA [NM_001244910] 
                   
               
               
                 TIMELESS interacting protein (TIPIN), mRNA [NM_017858] 
                 TIPIN 
               
               
                 nucleolar and spindle associated protein 1 (NUSAP1), transcript variant 1, 
                 NUSAP1 
               
               
                 mRNA [NM_016359] 
                   
               
               
                 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 
                 TAF7 
               
               
                 55 kDa (TAF7), mRNA [NM_005642] 
                   
               
               
                 GTPase, IMAP family member 6 (GIMAP6), transcript variant 1, mRNA 
                 GIMAP6 
               
               
                 [NM_024711] 
                   
               
               
                 DnaJ (Hsp40) homolog, subfamily A, member 3 (DNAJA3), nuclear gene 
                 DNAJA3 
               
               
                 encoding mitochondrial protein, transcript variant 1, mRNA [NM_005147] 
                   
               
               
                 p21 protein (Cdc42/Rac)-activated kinase 1 (PAK1), transcript variant 1, mRNA 
                 PAK1 
               
               
                 [NM_001128620] 
                   
               
               
                 alcohol dehydrogenase 5 (class III), chi polypeptide (ADH5), mRNA 
                 ADH5 
               
               
                 [NM_000671] 
                   
               
               
                 CD79a molecule, immunoglobulin-associated alpha (CD79A), transcript variant 
                 CD79A 
               
               
                 1, mRNA [NM_001783] 
                   
               
               
                 Fc receptor-like 2 (FCRL2), mRNA [NM_030764] 
                 FCRL2 
               
               
                 uridine phosphorylase 1 [Source: HGNC Symbol;Acc: 12576] [ENST00000457596] 
                 UPP1 
               
               
                 sialic acid binding Ig-like lectin 16 (gene/pseudogene) (SIGLEC16), non-coding 
                 SIGLEC16 
               
               
                 RNA [NR_002825] 
                   
               
               
                 PREDICTED: peptidyl-prolyl cis-trans isomerase A-like (LOC729313), miscRNA 
                 LOC729313 
               
               
                 [XR_132614] 
                   
               
               
                 T-cell leukemia/lymphoma 1A (TCL1A), transcript variant 1, mRNA 
                 TCL1A 
               
               
                 [NM_021966] 
                   
               
               
                 retinoblastoma-like 2 (p130) (RBL2), mRNA [NM_005611] 
                 RBL2 
               
               
                 RAN, member RAS oncogene family (RAN), mRNA [NM_006325] 
                 RAN 
               
               
                 adrenergic, beta-2-, receptor, surface (ADRB2), mRNA [NM_000024] 
                 ADRB2 
               
               
                 solute carrier family 16, member 3 (monocarboxylic acid transporter 4) 
                 SLC16A3 
               
               
                 (SLC16A3), transcript variant 2, mRNA [NM_001042422] 
                   
               
               
                 myosin IF (MYO1F), mRNA [NM_012335] 
                 MYO1F 
               
               
                 myeloid differentiation primary response gene (88) (MYD88), transcript variant 
                 MYD88 
               
               
                 2, mRNA [NM_002468] 
                   
               
               
                 solute carrier family 38, member 6 (SLC38A6), transcript variant 2, mRNA 
                 SLC38A6 
               
               
                 [NM_153811] 
                   
               
               
                 polymerase (DNA directed), alpha 2 (70 kD subunit) (POLA2), mRNA 
                 POLA2 
               
               
                 [NM_002689] 
                   
               
               
                 cytochrome b-245, beta polypeptide (CYBB), mRNA [NM_000397] 
                 CYBB 
               
               
                 WD repeat domain 92 (WDR92), mRNA [NM_138458] 
                 WDR92 
               
               
                 Spi-B transcription factor (Spi-1/PU.1 related) (SPIB), transcript variant 1, mRNA 
                 SPIB 
               
               
                 [NM_003121] 
                   
               
               
                 nucleoporin 88 kDa (NUP88), mRNA [NM_002532] 
                 NUP88 
               
               
                 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1), 
                 SERPING1 
               
               
                 transcript variant 1, mRNA [NM_000062] 
                   
               
               
                 serine peptidase inhibitor, Kunitz type, 2 (5PINT2), transcript variant a, mRNA 
                 SPINT2 
               
               
                 [NM_021102] 
                   
               
               
                 mutS homolog 6 ( E. coli ) (MSH6), mRNA [NM_000179] 
                 MSH6 
               
               
                 HESX homeobox 1 (HESX1), mRNA [NM_003865] 
                 HESX1 
               
               
                 non-SMC condensin 11 complex, subunit D3 (NCAPD3), mRNA [NM_015261] 
                 NCAPD3 
               
               
                 natural cytotoxicity triggering receptor 1 (NCR1), transcript variant 1, mRNA 
                 NCR1 
               
               
                 [NM_004829] 
                   
               
               
                 ATPase, class I, type 8B, member 4 (ATP8B4), mRNA [NM_024837] 
                 ATP8B4 
               
               
                 sideroflexin 3 (SFXN3), mRNA [NM_030971] 
                 SFXN3 
               
               
                 vaccinia related kinase 1 (VRK1), mRNA [NM_003384] 
                 VRK1 
               
               
                 G protein-coupled receptor 82 (GPR82), mRNA [NM_080817] 
                 GPR82 
               
               
                 nuclear factor (erythroid-derived 2), 45 kDa (NFE2), transcript variant 1, mRNA 
                 NFE2 
               
               
                 [NM_006163] 
                   
               
               
                 pseudouridylate synthase 7 homolog ( S. cerevisiae ) (PUS7), mRNA 
                 PUS7 
               
               
                 [NM_019042] 
                   
               
               
                 E2F transcription factor 2 (E2F2), mRNA [NM_004091] 
                 E2F2 
               
               
                 transcription termination factor, RNA polymerase II (TTF2), mRNA 
                 TTF2 
               
               
                 [NM_003594] 
                   
               
               
                 SCL/TAL1 interrupting locus (STIL), transcript variant 1, mRNA [NM_001048166] 
                 STIL 
               
               
                 sterile alpha motif domain containing 9-like (SAMD9L), mRNA [NM_152703] 
                 SAMD9L 
               
               
                 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19 kDa (NDUFA8), 
                 NDUFA8 
               
               
                 nuclear gene encoding mitochondrial protein, mRNA [NM_014222] 
                   
               
               
                 processing of precursor 5, ribonuclease P/MRP subunit ( S. cerevisiae ) (POP5), 
                 POP5 
               
               
                 transcript variant 1, mRNA [NM_015918] 
                   
               
               
                 centrosomal protein 152 kDa (CEP152), transcript variant 2, mRNA 
                 CEP152 
               
               
                 [NM_014985] 
                   
               
               
                 anaphase promoting complex subunit 10 (ANAPC10), mRNA [NM_014885] 
                 ANAPC10 
               
               
                 CD200 molecule (CD200), transcript variant 2, mRNA [NM_001004196] 
                 CD200 
               
               
                 leucine rich repeat and fibronectin type III domain containing 4 (LRFN4), mRNA 
                 LRFN4 
               
               
                 [NM_024036] 
                   
               
               
                 cyclin-dependent kinase 4 (CDK4), mRNA [NM_000075] 
                 CDK4 
               
               
                 structural maintenance of chromosomes 3 (SMC3), mRNA [NM_005445] 
                 SMC3 
               
               
                 retinoic acid receptor, alpha (RARA), transcript variant 2, mRNA 
                 RARA 
               
               
                 [NM_001024809] 
                   
               
               
                 chemokine (C-C motif) receptor 5 (CCR5), transcript variant A, mRNA 
                 CCR5 
               
               
                 [NM_000579] 
                   
               
               
                 superoxide dismutase 2, mitochondrial (SOD2), nuclear gene encoding 
                 SOD2 
               
               
                 mitochondrial protein, transcript variant 2, mRNA [NM_001024465] 
                   
               
               
                 interferon-induced protein with tetratricopeptide repeats 1 (IFIT1), transcript 
                 IFIT1 
               
               
                 variant 2, mRNA [NM_001548] 
                   
               
               
                 cytoskeleton associated protein 5 (CKAP5), transcript variant 1, mRNA 
                 CKAP5 
               
               
                 [NM_001008938] 
                   
               
               
                 myxovirus (influenza virus) resistance 2 (mouse) (MX2), mRNA [NM_002463] 
                 MX2 
               
               
                 aryl hydrocarbon receptor nuclear translocator-like 2 (ARNTL2), transcript 
                 ARNTL2 
               
               
                 variant 1, mRNA [NM_020183] 
                   
               
               
                 cyclin F (CCNF), mRNA [NM_001761] 
                 CCNF 
               
               
                 cytotoxic and regulatory T cell molecule (CRTAM), mRNA [NM_019604] 
                 CRTAM 
               
               
                 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, 
                 SMARCAL1 
               
               
                 subfamily a-like 1 (SMARCAL1), transcript variant 1, mRNA [NM_014140] 
                   
               
               
                 prostaglandin I2 (prostacyclin) receptor (IP) (PTGIR), mRNA [NM_000960] 
                 PTGIR 
               
               
                 MHC class I polypeptide-related sequence B (MICB), mRNA [NM_005931] 
                 MICB 
               
               
                 caspase 7, apoptosis-related cysteine peptidase (CASP7), transcript variant 
                 CASP7 
               
               
                 delta, mRNA [NM_033338] 
                   
               
               
                 ataxia telangiectasia and Rad3 related (ATR), mRNA [NM_001184] 
                 ATR 
               
               
                 tumor necrosis factor, alpha-induced protein 6 (TNFAIP6), mRNA [NM_007115] 
                 TNFAIP6 
               
               
                 chemokine (C-X-C motif) receptor 5 (CXCR5), transcript variant 2, mRNA 
                 CXCR5 
               
               
                 [NM_032966] 
                   
               
               
                 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58 kDa (EIF2B3), 
                 EIF2B3 
               
               
                 transcript variant 1, mRNA [NM_020365] 
                   
               
               
                 topoisomerase (DNA) II binding protein 1 (TOPBP1), mRNA [NM_007027] 
                 TOPBP1 
               
               
                 jumonji domain containing 4 (JMJD4), transcript variant 1, mRNA [NM_023007] 
                 JMJD4 
               
               
                 polo-like kinase 1 (PLK1), mRNA [NM_005030] 
                 PLK1 
               
               
                 colony stimulating factor 2 receptor, beta, low-affinity (granulocyte- 
                 CSF2RB 
               
               
                 macrophage) (CSF2RB), mRNA [NM_000395] 
                   
               
               
                 AF4/FMR2 family, member 3 [Source: HGNC Symbol;Acc: 6473] 
                 AFF3 
               
               
                 [ENST00000483600] 
                   
               
               
                 3-hydroxyisobutyryl-CoA hydrolase (HIBCH), nuclear gene encoding 
                 HIBCH 
               
               
                 mitochondrial protein, transcript variant 2, mRNA [NM_198047] 
                   
               
               
                 S-phase kinase-associated protein 2 (p45) (SKP2), transcript variant 2, mRNA 
                 SKP2 
               
               
                 [NM_032637] 
                   
               
               
                 myosin VIIB (MYO7B), mRNA [NM_001080527] 
                 MYO7B 
               
               
                 CCAAT/enhancer binding protein (C/EBP), epsilon (CEBPE), mRNA 
                 CEBPE 
               
               
                 [NM_001805] 
                   
               
               
                 Ral GEF with PH domain and SH3 binding motif 2 (RALGPS2), mRNA 
                 RALGPS2 
               
               
                 [NM_152663] 
                   
               
               
                 minichromosome maintenance complex component 5 (MCM5), mRNA 
                 MCM5 
               
               
                 [NM_006739] 
                   
               
               
                 interferon induced with helicase C domain 1 (IFIH1), mRNA [NM_022168] 
                 IFIH1 
               
               
                 presenilin 2 (Alzheimer disease 4) (PSEN2), transcript variant 1, mRNA 
                 PSEN2 
               
               
                 [NM_000447] 
                   
               
               
                 single-stranded DNA binding protein 1 (SSBP1), nuclear gene encoding 
                 SSBP1 
               
               
                 mitochondrial protein, mRNA [NM_003143] 
                   
               
               
                 CHK2 checkpoint homolog ( S. pombe ) (CHEK2), transcript variant 2, mRNA 
                 CHEK2 
               
               
                 [NM_145862] 
                   
               
               
                 thymopoietin (TMPO), transcript variant 2, mRNA [NM_001032283] 
                 TMPO 
               
               
                 cell division cycle 23 homolog ( S. cerevisiae ) (CDC23), mRNA [NM_004661] 
                 CDC23 
               
               
                 trichoplein, keratin filament binding (TCHP), transcript variant 1, mRNA 
                 TCHP 
               
               
                 [NM_032300] 
                   
               
               
                 pre-B lymphocyte 3 (VPREB3), mRNA [NM_013378] 
                 VPREB3 
               
               
                 CD72 molecule [Source: HGNC Symbol;Acc: 1696] [ENST00000378431] 
                 CD72 
               
               
                 N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) (NPL), 
                 NPL 
               
               
                 transcript variant 3, mRNA [NM_001200056] 
                   
               
               
                 deoxythymidylate kinase (thymidylate kinase) (DTYMK), transcript variant 1, 
                 DTYMK 
               
               
                 mRNA [NM_012145] 
                   
               
               
                 TRAF3 interacting protein 3 (TRAF3IP3), mRNA [NM_025228] 
                 TRAF3IP3 
               
               
                 coronin, actin binding protein, 1A (CORO1A), transcript variant 2, mRNA 
                 CORO1A 
               
               
                 [NM_007074] 
                   
               
               
                 G protein-coupled receptor 137B (GPR137B), mRNA [NM_003272] 
                 GPR137B 
               
               
                 polymerase (DNA-directed), delta 3, accessory subunit (POLD3), mRNA 
                 POLD3 
               
               
                 [NM_006591] 
                   
               
               
                 Fc receptor-like A (FCRLA), transcript variant 2, mRNA [NM_032738] 
                 FCRLA 
               
               
                 excision repair cross-complementing rodent repair deficiency, 
                 ERCC6L 
               
               
                 complementation group 6-like (ERCC6L), mRNA [NM_017669] 
                   
               
               
                 kinesin family member 23 (KIF23), transcript variant 1, mRNA [NM_138555] 
                 KIF23 
               
               
                 major histocompatibility complex, class II, DO beta (HLA-DOB), mRNA 
                 HLA-DOB 
               
               
                 [NM_002120] 
                   
               
               
                 asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. 
                 ALG8 
               
               
                 cerevisiae) (ALG8), transcript variant 2, mRNA [NM_001007027] 
                   
               
               
                 proteasome (prosome, macropain) subunit, alpha type, 3 (PSMA3), transcript 
                 PSMA3 
               
               
                 variant 1, mRNA [NM_002788] 
                   
               
               
                 centromere protein N (CENPN), transcript variant 3, mRNA [NM_018455] 
                 CENPN 
               
               
                 acyl-CoA dehydrogenase, C-4 to C-12 straight chain (ACADM), nuclear gene 
                 ACADM 
               
               
                 encoding mitochondrial protein, transcript variant 1, mRNA [NM_000016] 
                   
               
               
                 radical S-adenosyl methionine domain containing 2 (RSAD2), mRNA 
                 RSAD2 
               
               
                 [NM_080657] 
                   
               
               
                 tetraspanin 13 (TSPAN13), mRNA [NM_014399] 
                 TSPAN13 
               
               
                 breast cancer 1, early onset (BRCA1), transcript variant 2, mRNA [NM_007300] 
                 BRCA1 
               
               
                 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 (ABCC3), transcript 
                 ABCC3 
               
               
                 variant 1, mRNA [NM_003786] 
                   
               
               
                 major histocompatibility complex, class II, DO alpha (HLA-DOA), mRNA 
                 HLA-DOA 
               
               
                 [NM_002119] 
                   
               
               
                 V-set and immunoglobulin domain containing 10 (VSIG10), mRNA 
                 VSIG10 
               
               
                 [NM_019086] 
                   
               
               
                 WAS protein homolog associated with actin, golgi membranes and 
                 WHAMM 
               
               
                 microtubules (WHAMM), mRNA [NM_001080435] 
                   
               
               
                 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary 
                 CEACAM1 
               
               
                 glycoprotein) (CEACAM1), transcript variant 5, mRNA [NM_001184816] 
                   
               
               
                 transcription factor Dp-1 (TFDP1), transcript variant 1, mRNA [NM_007111] 
                 TFDP1 
               
               
                 kinesin family member 20B (KIF20B), mRNA [NM_016195] 
                 KIF20B 
               
               
                 family with sequence similarity 129, member C (FAM129C), transcript variant 2, 
                 FAM129C 
               
               
                 mRNA [NM_001098524] 
                   
               
               
                 MACRO domain containing 2 (MACROD2), transcript variant 1, mRNA 
                 MACROD2 
               
               
                 [NM_080676] 
                   
               
               
                 peptidylprolyl isomerase (cyclophilin)-like 4 (PPIL4), mRNA [NM_139126] 
                 PPIL4 
               
               
                 CD24 molecule (CD24), mRNA [NM_013230] 
                 CD24 
               
               
                 family with sequence similarity 129, member A (FAM129A), transcript variant 2, 
                 FAM129A 
               
               
                 mRNA [NM_052966] 
                   
               
               
                 zinc finger protein 467 (ZNF467), mRNA [NM_207336] 
                 ZNF467 
               
               
                 ADAM metallopeptidase domain 28 (ADAM28), transcript variant 3, mRNA 
                 ADAM28 
               
               
                 [NM_021777] 
                   
               
               
                 SAM domain and HD domain 1 (SAMHD1), mRNA [NM_015474] 
                 SAMHD1 
               
               
                 epithelial cell transforming sequence 2 oncogene (ECT2), mRNA [NM_018098] 
                 ECT2 
               
               
                 kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (KMO), mRNA 
                 KMO 
               
               
                 [NM_003679] 
                   
               
               
                 ASF1 anti-silencing function 1 homolog B ( S. cerevisiae ) (ASF1B), mRNA 
                 ASF1B 
               
               
                 [NM_018154] 
                   
               
               
                 proline-serine-threonine phosphatase interacting protein 1 (PSTPIP1), mRNA 
                 PSTPIP1 
               
               
                 [NM_003978] 
                   
               
               
                 RMI1, RecQ mediated genome instability 1, homolog ( S. cerevisiae ) (RMI1), 
                 RMI1 
               
               
                 mRNA [NM_024945] 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 2 
               
               
                   
               
               
                 marker genes (full name and accession number as set out in table 1) 
               
               
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
            
               
                 LOC572558 
                 KIAA0101 
                 HJURP 
                 SLAMF6 
                 ENPP5 
               
               
                 USH1G 
                 IFI27 
                 STAP1 
                 KIR2DS2 
                 IL18RAP 
               
               
                 BMP2 
                 RAD51 
                 TOP2A 
                 XLOC_ 
                 GRAP2 
               
               
                   
                   
                   
                 004032 
                   
               
               
                 KIF18A 
                 TYMS 
                 XLOC_l2_ 
                 PRF1 
                 SH2D2A 
               
               
                   
                   
                 010897 
                   
                   
               
               
                 ANLN 
                 E2F8 
                 PPP2R2B 
                 GINS2 
                 CR1 
               
               
                 GP5 
                 PDGFRB 
                 SPC25 
                 CDC45 
                 IQCD 
               
               
                 SKA3 
                 CHI3L1 
                 KIAA1671 
                 TBX21 
                 CCL5 
               
               
                 TTK 
                 IFNG 
                 BUB1 
                 GZMA 
                 KLRD1 
               
               
                 OLFM4 
                 CDT1 
                 GPR56 
                 NKG7 
                 CXCR3 
               
               
                 DLGAP5 
                 CCL20 
                 GZMM 
                 SGK1 
                 CD247 
               
               
                 MCM10 
                 DTL 
                 SAMD3 
                 PVRIG 
                 ZNF697 
               
               
                 SLPI 
                 LOC643650 
                 CTSW 
                 NEK2 
                 HOPX 
               
               
                 FASLG 
                 CCNA2 
                 PTGFRN 
                 TARP 
                 IL1B 
               
               
                 SLC7A8 
                 RGS9 
                 XLOC_ 
                 BIRC5 
                 KLRC1 
               
               
                   
                   
                 006752 
                   
                   
               
               
                 EXO1 
                 CEP55 
                 GNLY 
                 CST7 
                 ZNF503 
               
               
                 FGFBP2 
                 POLE2 
                 LINC00239 
                 IL2RB 
                 XLOC_ 
               
               
                   
                   
                   
                   
                 004924 
               
               
                 CXCL1 
                 ASPM 
                 CDCA2 
                 MND1 
                 ZAP70 
               
               
                 MELK 
                 TGFBR3 
                 GZMH 
                 S1PR5 
                 CENPF 
               
               
                 RRM2 
                 RPGRIP1 
                 BUB1B 
                 STK32B 
                 PTPRCAP 
               
               
                 LOC572558 
                 KIR2DL2 
                 UBE2C 
                 KLRF1 
                 KLRC3 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 2B 
               
               
                   
               
               
                 marker genes (full name and accession number as set out in table 1) 
               
               
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
            
               
                 LOC572558 
                 TYMS 
                 KIAA1671 
                 NKG7 
                 CXCR3 
               
               
                 USH1G 
                 E2F8 
                 BUB1 
                 SGK1 
                 CD247 
               
               
                 BMP2 
                 PDGFRB 
                 GPR56 
                 PVRIG 
                 ZNF697 
               
               
                 KIF18A 
                 CHI3L1 
                 GZMM 
                 NEK2 
                 HOPX 
               
               
                 ANLN 
                 IFNG 
                 SAMD3 
                 TARP 
                 IL1B 
               
               
                 GP5 
                 CCL20 
                 CTSW 
                 BIRC5 
                 KLRC1 
               
               
                 SKA3 
                 DTL 
                 PTGFRN 
                 CST7 
                 ZNF503 
               
               
                 TTK 
                 LOC643650 
                 XLOC_ 
                 IL2RB 
                 XLOC_ 
               
               
                   
                   
                 006752 
                   
                 004924 
               
               
                 OLFM4 
                 RGS9 
                 GNLY 
                 MND1 
                 ZAP70 
               
               
                 DLGAP5 
                 CEP55 
                 LINC00239 
                 S1PR5 
                 CENPF 
               
               
                 SLPI 
                 POLE2 
                 GZMH 
                 STK32B 
                 PTPRCAP 
               
               
                 FASLG 
                 ASPM 
                 BUB1B 
                 KLRF1 
                 KLRC3 
               
               
                 SLC7A8 
                 TGFBR3 
                 SLAMF6 
                 ENPP5 
                   
               
               
                 EXO1 
                 RPGRIP1 
                 KIR2DS2 
                 IL18RAP 
                   
               
               
                 FGFBP2 
                 KIR2DL2 
                 XLOC_ 
                 GRAP2 
                   
               
               
                   
                   
                 004032 
                   
                   
               
               
                 CXCL1 
                 HJURP 
                 PRF1 
                 SH2D2A 
                   
               
               
                 LOC572558 
                 STAP1 
                 GINS2 
                 CR1 
                   
               
               
                 KIAA0101 
                 XLOC_l2_ 
                 CDC45 
                 IQCD 
                   
               
               
                   
                 010897 
                   
                   
                   
               
               
                 IFI27 
                 PPP2R2B 
                 TBX21 
                 CCL5 
                   
               
               
                 RAD51 
                 SPC25 
                 GZMA 
                 KLRD1 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 3 
               
               
                   
               
               
                 marker genes (full name and accession number as set out in table 1) 
               
               
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
            
               
                 LOC572558 
                 MCM10 
                 IFI27 
                 LOC643650 
                 STAP1 
               
               
                 USH1G 
                 SLPI 
                 RAD51 
                 CCNA2 
                 TOP2A 
               
               
                 BMP2 
                 FASLG 
                 TYMS 
                 RGS9 
                 XLOC_l2_ 
               
               
                   
                   
                   
                   
                 010897 
               
               
                 KIF18A 
                 SLC7A8 
                 E2F8 
                 CEP55 
                 PPP2R2B 
               
               
                 ANLN 
                 EXO1 
                 PDGFRB 
                 POLE2 
                 SPC25 
               
               
                 GP5 
                 FGFBP2 
                 CHI3L1 
                 ASPM 
                 KIAA1671 
               
               
                 SKA3 
                 CXCL1 
                 IFNG 
                 TGFBR3 
                 BUB1 
               
               
                 TTK 
                 MELK 
                 CDT1 
                 RPGRIP1 
                 GPR56 
               
               
                 OLFM4 
                 RRM2 
                 CCL20 
                 KIR2DL2 
                 GZMM 
               
               
                 DLGAP5 
                 KIAA0101 
                 DTL 
                 HJURP 
                 SAMD3 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 3B 
               
               
                   
               
               
                 marker genes (full name and accession number as set out in table 1) 
               
               
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
            
               
                 LOC572558 
                 SLPI 
                 E2F8 
                 ASPM 
                 BUB1 
               
               
                 USH1G 
                 FASLG 
                 PDGFRB 
                 TGFBR3 
                 GPR56 
               
               
                 BMP2 
                 SLC7A8 
                 CHI3L1 
                 RPGRIP1 
                 GZMM 
               
               
                 KIF18A 
                 EXO1 
                 IFNG 
                 KIR2DL2 
                 SAMD3 
               
               
                 ANLN 
                 FGFBP2 
                 CCL20 
                 HJURP 
                   
               
               
                 GP5 
                 CXCL1 
                 DTL 
                 STAP1 
                   
               
               
                 SKA3 
                 KIAA0101 
                 LOC643650 
                 XLOC_l2_010897 
                   
               
               
                 TTK 
                 IFI27 
                 RGS9 
                 PPP2R2B 
                   
               
               
                 OLFM4 
                 RAD51 
                 CEP55 
                 SPC25 
                   
               
               
                 DLGAP5 
                 TYMS 
                 POLE2 
                 KIAA1671 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 4 
               
               
                   
               
               
                 marker genes (full name and accession number as set out in table 1) 
               
               
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
               
            
               
                 LOC572558 
                 GP5 
                 MCM10 
                 FGFBP2 
                 IFI27 
                 CHI3L1 
               
               
                 USH1G 
                 SKA3 
                 SLPI 
                 CXCL1 
                 RAD51 
                 IFNG 
               
               
                 BMP2 
                 TTK 
                 FASLG 
                 MELK 
                 TYMS 
                 CDT1 
               
               
                 KIF18A 
                 OLFM4 
                 SLC7A8 
                 RRM2 
                 E2F8 
                 CCL20 
               
               
                 ANLN 
                 DLGAP5 
                 EXO1 
                 KIAA0101 
                 PDGFRB 
                 DTL 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 4B 
               
               
                   
               
               
                 marker genes (full name and accession number as set out in table 1) 
               
               
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
               
            
               
                 LOC572558 
                 GP5 
                 SLPI 
                 CXCL1 
                 E2F8 
                 DTL 
               
               
                 USH1G 
                 SKA3 
                 FASLG 
                 KIAA0101 
                 PDGFRB 
                   
               
               
                 BMP2 
                 TTK 
                 SLC7A8 
                 IFI27 
                 CHI3L1 
                   
               
               
                 KIF18A 
                 OLFM4 
                 EXO1 
                 RAD51 
                 IFNG 
                   
               
               
                 ANLN 
                 DLGAP5 
                 FGFBP2 
                 TYMS 
                 CCL20 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 5 
               
               
                   
               
               
                 marker genes (full name and accession number as set out in table 1) 
               
               
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
            
               
                 LOC572558 
                 KIF18A 
                 SKA3 
                 DLGAP5 
                 FASLG 
               
               
                 USH1G 
                 ANLN 
                 TTK 
                 MCM10 
                 SLC7A8 
               
               
                 BMP2 
                 GP5 
                 OLFM4 
                 SLPI 
                 EXO1 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 5B 
               
               
                   
               
               
                 marker genes (full name and accession number as set out in table 1) 
               
               
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
            
               
                 LOC572558 
                 KIF18A 
                 SKA3 
                 DLGAP5 
                 SLC7A8 
               
               
                 USH1G 
                 ANLN 
                 TTK 
                 SLPI 
                 EXO1 
               
               
                 BMP2 
                 GP5 
                 OLFM4 
                 FASLG 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 6 
               
             
            
               
                   
               
               
                 marker genes for cancer, in particular prostate cancer  
               
            
           
           
               
               
            
               
                 Gene 
                   
               
               
                 Symbol 
                 Gene Title 
               
               
                   
               
               
                 COX7B 
                 cytochrome c oxidase subunit VIIb, mRNA  
               
               
                   
                 [NM_001866] 
               
               
                 LY96 
                 lymphocyte antigen 96, mRNA [NM_015364] 
               
               
                 FIGNL1 
                 fidgetin-like 1, mRNA [NM_001042762] 
               
               
                 FOSL1 
                 FOS-like antigen 1, mRNA [NM_005438] 
               
               
                 S100A8 
                 S100 calcium binding protein A8, mRNA  
               
               
                   
                 [NM_002964] 
               
               
                 GFRA3 
                 GDNF family receptor alpha 3, mRNA [NM_001496] 
               
               
                 REEP1 
                 receptor accessory protein 1, mRNA [NM_022912] 
               
               
                 SUV39H2 
                 suppressor of variegation 3-9 homolog 2 ( Drosophila ),  
               
               
                   
                 mRNA [NM_024670] 
               
               
                 ZFYVE16 
                 zinc finger, FYVE domain containing 16, mRNA  
               
               
                   
                 [NM_001105251]  
               
               
                 NDUFA4 
                 NADH dehydrogenase (ubiquinone) 1 alpha  
               
               
                   
                 subcomplex, 4, 9 kDa, mRNA [NM_002489] 
               
               
                 FOXN1 
                 forkhead box N1, mRNA [NM_003593] 
               
               
                 KIR2DL4 
                 killer cell immunoglobulin-like receptor, two domains,  
               
               
                   
                 long cytoplasmic tail, 4, mRNA [NM_002255] 
               
               
                 GOLT1B 
                 golgi transport 1B, mRNA [NM_016072] 
               
               
                 NLRC3 
                 NLR family, CARD domain containing 3, mRNA  
               
               
                   
                 [NM_178844, AK090476] 
               
               
                 ACTR6 
                 ARP6 actin-related protein 6 homolog (yeast), mRNA  
               
               
                   
                 [NM_022496]  
               
               
                 PLEKHF2 
                 pleckstrin homology domain containing, family F  
               
               
                   
                 (with FYVE domain) member 2, mRNA [NM_024613] 
               
               
                 TFEC 
                 transcription factor EC, mRNA [NM_012252] 
               
               
                 LGALS2 
                 lectin, galactoside-binding, soluble, 2, mRNA  
               
               
                   
                 [AK130682, NM_006498] 
               
               
                 MSH6 
                 mutS homolog 6, mRNA [NM_000179] 
               
               
                 TARP 
                 TCR gamma alternate reading frame protein, mRNA  
               
               
                   
                 [NM_001003799] 
               
               
                 MND1 
                 meiotic nuclear divisions 1 homolog ( S. cerevisiae ),  
               
               
                   
                 mRNA [NM_032117] 
               
               
                 S100A12 
                 S100 calcium binding protein A12, mRNA  
               
               
                   
                 [NM_005621]  
               
               
                 AGL 
                 amylo-alpha-1, 6-glucosidase, 4-alpha- 
               
               
                   
                 glucanotransferase, mRNA [NM_000028] 
               
               
                 NUPL2 
                 nucleoporin like 2, mRNA [BC039333, NM_007342] 
               
               
                 PKMYT1 
                 protein kinase, membrane associated tyrosine/threonine  
               
               
                   
                 1, mRNA [NM_182687] 
               
               
                 PTAFR 
                 platelet-activating factor receptor, mRNA  
               
               
                   
                 [NM_000952, NM_001164722] 
               
               
                 VSTM1 
                 V-set and transmembrane domain containing 1, mRNA  
               
               
                   
                 [NM_198481] 
               
               
                 SAMHD1 
                 SAM domain and HD domain 1, mRNA [NM_015474] 
               
               
                 ASPA 
                 aspartoacylase, mRNA [NM_000049] 
               
               
                 PPP1R12A 
                 protein phosphatase 1, regulatory subunit 12A, mRNA  
               
               
                   
                 [NM_002480]  
               
               
                 UQCRQ 
                 ubiquinol-cytochrome c reductase, complex III subunit  
               
               
                   
                 VII, 9.5 kDa, mRNA [NM_014402] 
               
               
                 OSMR 
                 oncostatin M receptor, mRNA [NM_003999,  
               
               
                   
                 NM_001168355] 
               
               
                 SP3 
                 Sp3 transcription factor, mRNA [NM_003111] 
               
               
                 JPH2 
                 junctophilin 2, mRNA [NM_175913, NM_020433] 
               
               
                 APCDD1 
                 adenomatosis polyposis coli down-regulated 1, mRNA  
               
               
                   
                 [NM_153000]  
               
               
                 ABCG2 
                 ATP-binding cassette, sub-family G (WHITE),  
               
               
                   
                 member 2, mRNA [NM_004827] 
               
               
                 TLR7 
                 toll-like receptor 7, mRNA [NM_016562] 
               
               
                 ATP5C1 
                 ATP synthase, H+ transporting, mitochondrial F1  
               
               
                   
                 complex, gamma polypeptide 1, mRNA  
               
               
                   
                 [NM_005174] 
               
               
                 GINS1 
                 GINS complex subunit 1 (Psf1 homolog), mRNA  
               
               
                   
                 [NM_021067] 
               
               
                 CKS2 
                 CDC28 protein kinase regulatory subunit 2, mRNA  
               
               
                   
                 [NM_001827]  
               
               
                 NOC3L 
                 nucleolar complex associated 3 homolog  
               
               
                   
                 ( S. cerevisiae ), mRNA [NM_022451] 
               
               
                 DEK 
                 DEK oncogene, mRNA [NM_003472] 
               
               
                 HNMT 
                 histamine N-methyltransferase, mRNA [NM_006895,  
               
               
                   
                 NM_001024074, NM_001024075] 
               
               
                 MS4A4A 
                 membrane-spanning 4-domains, subfamily A, member  
               
               
                   
                 4A, mRNA [NM_024021] 
               
               
                 TMEM55A 
                 transmembrane protein 55A, mRNA [NM_018710] 
               
               
                 TMX1 
                 thioredoxin-related transmembrane protein 1, mRNA  
               
               
                   
                 [NM_030755] 
               
               
                 USP1 
                 ubiquitin specific peptidase 1, mRNA [NM_003368] 
               
               
                 CCDC80 
                 coiled-coil domain containing 80, mRNA  
               
               
                   
                 [NM_199511] 
               
               
                 PCNP 
                 PEST proteolytic signal containing nuclear protein,  
               
               
                   
                 mRNA [NM_020357] 
               
               
                 SHCBP1 
                 SHC SH2-domain binding protein 1, mRNA  
               
               
                   
                 [NM_024745] 
               
               
                 PANK3 
                 pantothenate kinase 3, mRNA [BX648891,  
               
               
                   
                 NM_024594]  
               
               
                 PAQR3 
                 progestin and adipoQ receptor family member III,  
               
               
                   
                 mRNA [NM_001040202, BC031256] 
               
               
                 RNF138 
                 ring finger protein 138, E3 ubiquitin protein ligase,  
               
               
                   
                 mRNA [NM_016271] 
               
               
                 CD302 
                 CD302 molecule, mRNA [NM_014880] 
               
               
                 NUP35 
                 nucleoporin 35 kDa, mRNA [NM_138285,  
               
               
                   
                 NM_001287585]  
               
               
                 IMPA1 
                 inositol(myo)-1(or 4)-monophosphatase 1, mRNA  
               
               
                   
                 [NM_001144879, NM_005536] 
               
               
                 MS4A7 
                 membrane-spanning 4-domains, subfamily A, member  
               
               
                   
                 7, mRNA [NM_021201] 
               
               
                 SGMS1 
                 sphingomyelin synthase 1, mRNA [NM_147156] 
               
               
                 GALNT7 
                 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N- 
               
               
                   
                 acetylgalactosaminyltransferase 7 (GalNAc-T7),  
               
               
                   
                 mRNA [NM_017423] 
               
               
                 CA14 
                 carbonic anhydrase XIV, mRNA [NM_012113] 
               
               
                 RHOU 
                 ras homolog family member U, mRNA [NM_021205] 
               
               
                 PHTF2 
                 putative homeodomain transcription factor 2, mRNA  
               
               
                   
                 [NM_001127360, NM_020432] 
               
               
                 S100A9 
                 S100 calcium binding protein A9, mRNA  
               
               
                   
                 [NM_002965] 
               
               
                 FAM198B 
                 family with sequence similarity 198, member B,  
               
               
                   
                 mRNA [NM_016613] 
               
               
                 ST3GAL6 
                 ST3 beta-galactoside alpha-2,3-sialyltransferase 6,  
               
               
                   
                 mRNA [NM_006100] 
               
               
                 CLK4 
                 CDC-like kinase 4, mRNA [NM_020666] 
               
               
                 CLEC12A 
                 C-type lectin domain family 12, member A, mRNA  
               
               
                   
                 [NM_138337] 
               
               
                 GCA 
                 grancalcin, EF-hand calcium binding protein, mRNA  
               
               
                   
                 [NM_012198] 
               
               
                 VNN2 
                 vanin 2, mRNA [NM_004665] 
               
               
                 C1GALT1C1  
                 C1GALT1-specific chaperone 1, mRNA  
               
               
                   
                 [NM_152692] 
               
               
                 DUSP6 
                 dual specificity phosphatase 6, mRNA [NM_001946] 
               
               
                 TNFAIP8 
                 tumor necrosis factor, alpha-induced protein 8, mRNA  
               
               
                   
                 [NM_001286813, NM_014350] 
               
               
                 TLR4 
                 toll-like receptor 4, mRNA [NM_138554] 
               
               
                 FBLN1 
                 fibulin 1, mRNA [NM_001996, NM_006486] 
               
               
                 LRRK2 
                 leucine-rich repeat kinase 2, mRNA [NM_198578,  
               
               
                   
                 AK127729] 
               
               
                 SLC46A2 
                 solute carrier family 46, member 2, mRNA  
               
               
                   
                 [NM_033051] 
               
               
                 KIAA1468 
                 KIAA1468, mRNA [NM_020854] 
               
               
                 AIF1 
                 allograft inflammatory factor 1, mRNA [NM_004847] 
               
               
                 HK3 
                 hexokinase 3 (white cell), mRNA [NM_002115] 
               
               
                 SFRP4 
                 secreted frizzled-related protein 4, mRNA  
               
               
                   
                 [NM_003014] 
               
               
                 ARFIP1 
                 ADP-ribosylation factor interacting protein 1, mRNA  
               
               
                   
                 [NM_001025595] 
               
               
                 COX6C 
                 cytochrome c oxidase subunit VIc, mRNA  
               
               
                   
                 [NM_004374] 
               
               
                 DMD 
                 dystrophin, mRNA [NM_004021, BC036103,  
               
               
                   
                 NM_004010] 
               
               
                 KYNU 
                 kynureninase, mRNA [NM_001032998] 
               
               
                 PIK3C2A 
                 phosphatidylinositol-4-phosphate 3-kinase, catalytic  
               
               
                   
                 subunit type 2 alpha, mRNA [NM_002645] 
               
               
                 NDUFB1 
                 NADH dehydrogenase (ubiquinone) 1 beta  
               
               
                   
                 subcomplex, 1, 7 kDa, mRNA [NM_004545] 
               
               
                 VNN1 
                 vanin 1, mRNA [NM_004666] 
               
               
                 MBNL1 
                 muscleblind-like splicing regulator 1, mRNA  
               
               
                   
                 [NM_021038] 
               
               
                 ABCA1 
                 ATP-binding cassette, sub-family A (ABC1), member  
               
               
                   
                 1, mRNA [NM_005502] 
               
               
                 PID1 
                 phosphotyrosine interaction domain containing 1,  
               
               
                   
                 mRNA [NM_017933] 
               
               
                 SRP9 
                 signal recognition particle 9 kDa, mRNA  
               
               
                   
                 [NM_001130440, NM_003133] 
               
               
                 MAD2L1 
                 MAD2 mitotic arrest deficient-like 1 (yeast), mRNA  
               
               
                   
                 [NM_002358] 
               
               
                 GLIPR1 
                 GLI pathogenesis-related 1, mRNA [NM_006851] 
               
               
                 NUP107 
                 nucleoporin 107 kDa, mRNA [NM_020401] 
               
               
                 GZMK 
                 granzyme K (granzyme 3; tryptase II), mRNA  
               
               
                   
                 [NM_002104] 
               
               
                 STAG2 
                 stromal antigen 2, mRNA [NM_001042749,  
               
               
                   
                 NM_001042751]  
               
               
                 NDUFB3 
                 NADH dehydrogenase (ubiquinone) 1 beta  
               
               
                   
                 subcomplex, 3, 12 kDa, mRNA [NM_001257102] 
               
               
                 CYP1B1 
                 cytochrome P450, family 1, subfamily B, polypeptide  
               
               
                   
                 1, mRNA [NM_000104] 
               
               
                 MYBL2 
                 v-myb avian myeloblastosis viral oncogene homolog- 
               
               
                   
                 like 2, mRNA [NM_002466] 
               
               
                 KLF1 
                 Kruppel-like factor 1 (erythroid), mRNA  
               
               
                   
                 [NM_006563] 
               
               
                 IFI30 
                 interferon, gamma-inducible protein 30, mRNA  
               
               
                   
                 [NM_006332] 
               
               
                 ICOS 
                 inducible T-cell co-stimulator, mRNA [NM_012092] 
               
               
                 TNFSF11 
                 tumor necrosis factor (ligand) superfamily, member 11,  
               
               
                   
                 mRNA [NM_003701, NM_033012] 
               
               
                 NDUFB2 
                 NADH dehydrogenase (ubiquinone) 1 beta  
               
               
                   
                 subcomplex, 2, 8 kDa, mRNA [NM_004546] 
               
               
                 TGM2 
                 transglutaminase 2, mRNA [NM_004613,  
               
               
                   
                 NM_198951] 
               
               
                 CUL5 
                 cullin 5, mRNA [NM_003478] 
               
               
                 CD28 
                 CD28 molecule, mRNA [NM_006139] 
               
               
                 SGK1 
                 serum/glucocorticoid regulated kinase 1, mRNA  
               
               
                   
                 [NM_005627]  
               
               
                 PLA2G7 
                 phospholipase A2, group VII (platelet-activating  
               
               
                   
                 factor acetylhydrolase, plasma), mRNA [NM_005084] 
               
               
                 RMI1 
                 RecQ mediated genome instability 1, mRNA  
               
               
                   
                 [NM_024945] 
               
               
                 GPSM2 
                 G-protein signaling modulator 2, mRNA  
               
               
                   
                 [NM_013296] 
               
               
                 ZDHHC17 
                 zinc finger, DHHC-type containing 17, mRNA  
               
               
                   
                 [NM_015336]  
               
               
                 CCR2 
                 chemokine (C-C motif) receptor 2, mRNA  
               
               
                   
                 [NM_001123041, NM_001123396] 
               
               
                 FCN1 
                 ficolin (collagen/fibrinogen domain containing) 1,  
               
               
                   
                 mRNA [NM_002003] 
               
               
                 ZWINT 
                 ZW10 interacting kinetochore protein, mRNA  
               
               
                   
                 [NM_032997]  
               
               
                 AMICA1 
                 adhesion molecule, interacts with CXADR antigen 1,  
               
               
                   
                 mRNA [AK057590, NM_153206] 
               
               
                 CLEC7A 
                 C-type lectin domain family 7, member A, mRNA  
               
               
                   
                 [NM_197947, NM_197954] 
               
               
                 ERBB2IP 
                 ebb2 interacting protein, mRNA [NM_018695] 
               
               
                 MSH2 
                 mutS homolog 2, mRNA [NM_000251] 
               
               
                 RIN2 
                 Ras and Rab interactor 2, mRNA [NM_018993] 
               
               
                 MORC3 
                 MORC family CW-type zinc finger 3, mRNA  
               
               
                   
                 [NM_015358] 
               
               
                 MFSD1 
                 major facilitator superfamily domain containing 1,  
               
               
                   
                 mRNA [NM_022736] 
               
               
                 KCNJ2 
                 potassium inwardly-rectifying channel, subfamily J,  
               
               
                   
                 member 2, mRNA [NM_000891] 
               
               
                 LMNB1 
                 lamin B1, mRNA [NM_005573] 
               
               
                 CCT2 
                 chaperonin containing TCP1, subunit 2 (beta), mRNA  
               
               
                   
                 [NM_006431] 
               
               
                 IFNG 
                 interferon, gamma, mRNA [NM_000619] 
               
               
                 EEF1G 
                 eukaryotic translation elongation factor 1 gamma,  
               
               
                   
                 mRNA [NM_001404] 
               
               
                 CSTA 
                 cystatin A (stefin A), mRNA [NM_005213] 
               
               
                 MYBL1 
                 v-myb avian myeloblastosis viral oncogene homolog- 
               
               
                   
                 like 1, mRNA [NM_001294282, NM_001080416] 
               
               
                 MNDA 
                 myeloid cell nuclear differentiation antigen, mRNA  
               
               
                   
                 [NM_002432] 
               
               
                 PAQR9 
                 progestin and adipoQ receptor family member IX,  
               
               
                   
                 mRNA [NM_198504] 
               
               
                 ZBTB11 
                 zinc finger and BTB domain containing 11, mRNA  
               
               
                   
                 [NM_014415] 
               
               
                 RBP7 
                 retinol binding protein 7, cellular, mRNA  
               
               
                   
                 [NM_052960] 
               
               
                 ZNF700 
                 zinc finger protein 700, mRNA [NM_144566] 
               
               
                 BST1 
                 bone marrow stromal cell antigen 1, mRNA  
               
               
                   
                 [NM_004334] 
               
               
                 ATP5O 
                 ATP synthase, H+ transporting, mitochondrial F1  
               
               
                   
                 complex, O subunit, mRNA [NM_001697] 
               
               
                 ATAD2 
                 ATPase family, AAA domain containing 2, mRNA  
               
               
                   
                 [NM_014109] 
               
               
                 DLGAP5 
                 discs, large ( Drosophila ) homolog-associated protein  
               
               
                   
                 5, mRNA [NM_014750] 
               
               
                 NOD2 
                 nucleotide-binding oligomerization domain containing  
               
               
                   
                 2, mRNA [NM_022162] 
               
               
                 LILRA3 
                 leukocyte immunoglobulin-like receptor, subfamily A  
               
               
                   
                 (without TM domain), member 3, mRNA  
               
               
                   
                 [NM_006865] 
               
               
                 CLEC4A 
                 C-type lectin domain family 4, member A, mRNA  
               
               
                   
                 [NM_016184]  
               
               
                 TNFSF13B 
                 tumor necrosis factor (ligand) superfamily, member  
               
               
                   
                 13b, mRNA [NM_006573] 
               
               
                 CSF2RA 
                 colony stimulating factor 2 receptor, alpha, low-affinity  
               
               
                   
                 (granulocyte-macrophage), mRNA [NM_172249] 
               
               
                 BRI3 
                 brain protein I3, mRNA [NM_001159491,  
               
               
                   
                 NM_015379] 
               
               
                 RNF6 
                 ring finger protein (C3H2C3 type) 6, mRNA  
               
               
                   
                 [NM_005977] 
               
               
                 PTTG3P 
                 pituitary tumor-transforming 3, pseudogene, mRNA  
               
               
                   
                 [NR_002734] 
               
               
                 HSPD1 
                 heat shock 60 kDa protein 1 (chaperonin), mRNA  
               
               
                   
                 [NM_002156] 
               
               
                 GTF2H1 
                 general transcription factor IIH, polypeptide 1, 62 kDa,  
               
               
                   
                 mRNA [NM_005316] 
               
               
                 LMO2 
                 LIM domain only 2 (rhombotin-like 1), mRNA  
               
               
                   
                 [NM_005574] 
               
               
                 KIAA0101 
                 KIAA0101, mRNA [NM_014736] 
               
               
                 RFC5 
                 replication factor C (activator 1) 5, 36.5 kDa, mRNA  
               
               
                   
                 [NM_181578] 
               
               
                 RAD50 
                 RAD50 homolog ( S. cerevisiae ), mRNA  
               
               
                   
                 [NM_005732] 
               
               
                 FEN1 
                 flap structure-specific endonuclease 1, mRNA  
               
               
                   
                 [NM_004111]  
               
               
                 NUP54 
                 nucleoporin 54 kDa, mRNA [NM_017426] 
               
               
                 NDUFS4 
                 NADH dehydrogenase (ubiquinone) Fe—S protein 4,  
               
               
                   
                 18 kDa (NADH-coenzyme Q reductase), mRNA  
               
               
                   
                 [NM_002495]  
               
               
                 PTPN22 
                 protein tyrosine phosphatase, non-receptor type 22  
               
               
                   
                 (lymphoid), mRNA [NM_012411, NM_015967] 
               
               
                 CDKN3 
                 cyclin-dependent kinase inhibitor 3, mRNA  
               
               
                   
                 [NM_005192]  
               
               
                 MAGEA12 
                 melanoma antigen family A, 12, mRNA  
               
               
                   
                 [NM_005367] 
               
               
                 VPS4B 
                 vacuolar protein sorting 4 homolog B ( S. cerevisiae ),  
               
               
                   
                 mRNA [NM_004869] 
               
               
                 EIF3E 
                 eukaryotic translation initiation factor 3, subunit E,  
               
               
                   
                 mRNA [NM_001568] 
               
               
                 HLA-DPB1 
                 major histocompatibility complex, class II, DP beta 1,  
               
               
                   
                 mRNA [XM_006715078, NM_002121] 
               
               
                 NCAPG 
                 non-SMC condensin I complex, subunit G, mRNA  
               
               
                   
                 [NM_022346] 
               
               
                 CREBZF 
                 CREB/ATF bZIP transcription factor, mRNA  
               
               
                   
                 [NM_001039618] 
               
               
                 ITSN2 
                 intersectin 2, mRNA [NM_147152] 
               
               
                 QPCT 
                 glutaminyl-peptide cyclotransferase, mRNA  
               
               
                   
                 [NM_012413] 
               
               
                 BZW1 
                 basic leucine zipper and W2 domains 1, mRNA  
               
               
                   
                 [NM_014670] 
               
               
                 NDC80 
                 NDC80 kinetochore complex component, mRNA  
               
               
                   
                 [NM_006101] 
               
               
                 ZFAND6 
                 zinc finger, AN1-type domain 6, mRNA [NM_019006] 
               
               
                 KIR2DS2 
                 killer cell immunoglobulin-like receptor, two domains,  
               
               
                   
                 short cytoplasmic tail, 2, mRNA [NM_012312] 
               
               
                 CCNC 
                 cyclin C, mRNA [BC026272, NM_005190] 
               
               
                 EIF3H 
                 eukaryotic translation initiation factor 3, subunit H,  
               
               
                   
                 mRNA [NM_003756] 
               
               
                 FPR1 
                 formyl peptide receptor 1, mRNA [NM_002029] 
               
               
                 SLC40A1 
                 solute carrier family 40 (iron-regulated transporter),  
               
               
                   
                 member 1, mRNA [NM_014585] 
               
               
                 NUP160 
                 nucleoporin 160 kDa, mRNA [NM_015231] 
               
               
                 ENPP5 
                 ectonucleotide pyrophosphatase/phosphodiesterase 5  
               
               
                   
                 (putative), mRNA [NM_021572] 
               
               
                 MARCH1 
                 membrane-associated ring finger (C3HC4) 1, E3  
               
               
                   
                 ubiquitin protein ligase, mRNA [NM_017923] 
               
               
                 DPYD 
                 dihydropyrimidine dehydrogenase, mRNA  
               
               
                   
                 [NM_001160301, NM_000110] 
               
               
                 TGFBI 
                 transforming growth factor, beta-induced, 68 kDa,  
               
               
                   
                 mRNA [NM_000358] 
               
               
                 FBXO5 
                 F-box protein 5, mRNA [NM_001142522] 
               
               
                 ATP5L 
                 ATP synthase, H+ transporting, mitochondrial Fo  
               
               
                   
                 complex, subunit G, mRNA [NM_006476] 
               
               
                 G3BP2 
                 GTPase activating protein (SH3 domain) binding  
               
               
                   
                 protein 2, mRNA [NM_203505] 
               
               
                 MARCKS 
                 myristoylated alanine-rich protein kinase C substrate,  
               
               
                   
                 mRNA [D10522] 
               
               
                 SEC63 
                 SEC63 homolog ( S. cerevisiae ), mRNA [NM_007214] 
               
               
                 COX6A1 
                 cytochrome c oxidase subunit VIa polypeptide 1,  
               
               
                   
                 mRNA [NM_004373] 
               
               
                 PDGFA 
                 platelet-derived growth factor alpha polypeptide,  
               
               
                   
                 mRNA [NM_002607, NM_033023] 
               
               
                 CDT1 
                 chromatin licensing and DNA replication factor 1,  
               
               
                   
                 mRNA [NM_030928] 
               
               
                 KLRB1 
                 killer cell lectin-like receptor subfamily B, member 1,  
               
               
                   
                 mRNA [NM_002258] 
               
               
                 SMC2 
                 structural maintenance of chromosomes 2, mRNA  
               
               
                   
                 [NM_001042550] 
               
               
                 HLA-DMB 
                 major histocompatibility complex, class II, DM beta,  
               
               
                   
                 mRNA [NM_002118] 
               
               
                 TYROBP 
                 TYRO protein tyrosine kinase binding protein, mRNA  
               
               
                   
                 [NM_003332] 
               
               
                 GLT8D2 
                 glycosyltransferase 8 domain containing 2, mRNA  
               
               
                   
                 [NM_031302] 
               
               
                 GMNN 
                 geminin, DNA replication inhibitor, mRNA  
               
               
                   
                 [NM_015895] 
               
               
                 FGR 
                 feline Gardner-Rasheed sarcoma viral oncogene  
               
               
                   
                 homolog, mRNA [NM_001042747] 
               
               
                 COX5B 
                 cytochrome c oxidase subunit Vb, mRNA  
               
               
                   
                 [NM_001862] 
               
               
                 KIF18A 
                 kinesin family member 18A, mRNA [NM_031217] 
               
               
                 KIF20B 
                 kinesin family member 20B, mRNA [NM_016195,  
               
               
                   
                 NM_001284259] 
               
               
                 HOXD10 
                 homeobox D10, mRNA [NM_002148] 
               
               
                 RAD21 
                 RAD21 homolog ( S. pombe ), mRNA [NM_006265] 
               
               
                 MATR3 
                 matrin 3, mRNA [NM_199189] 
               
               
                 APOBEC3B 
                 apolipoprotein B mRNA editing enzyme, catalytic  
               
               
                   
                 polypeptide-like 3B, mRNA [NM_004900] 
               
               
                 HMOX1 
                 heme oxygenase (decycling) 1, mRNA [NM_002133] 
               
               
                 SLC31A2 
                 solute carrier family 31 (copper transporter), member  
               
               
                   
                 2, mRNA [NM_001860] 
               
               
                 VNN3 
                 vanin 3, mRNA [NM_001291703] 
               
               
                 TSPAN5 
                 tetraspanin 5, mRNA [NM_005723] 
               
               
                 GATA1 
                 GATA binding protein 1 (globin transcription factor 1),  
               
               
                   
                 mRNA [NM_002049] 
               
               
                 MARCO 
                 macrophage receptor with collagenous structure,  
               
               
                   
                 mRNA [NM_006770] 
               
               
                 SIRPB2 
                 signal-regulatory protein beta 2, mRNA  
               
               
                   
                 [NM_001122962] 
               
               
                 LST1 
                 leukocyte specific transcript 1, mRNA [NM_007161] 
               
               
                 CEACAM7 
                 carcinoembryonic antigen-related cell adhesion  
               
               
                   
                 molecule 7, mRNA [NM_006890] 
               
               
                 KIF20A 
                 kinesin family member 20A, mRNA [NM_005733] 
               
               
                 EED 
                 embryonic ectoderm development, mRNA  
               
               
                   
                 [NM_152991] 
               
               
                 RAB31 
                 RAB31, member RAS oncogene family, mRNA  
               
               
                   
                 [NM_006868] 
               
               
                 NDUFB6 
                 NADH dehydrogenase (ubiquinone) 1 beta  
               
               
                   
                 subcomplex, 6, 17 kDa, mRNA [NM_002493,  
               
               
                   
                 NM_182739] 
               
               
                 HSPE1 
                 heat shock 10 kDa protein 1, mRNA [NM_002157] 
               
               
                 TMEM154 
                 transmembrane protein 154, mRNA [NM_152680] 
               
               
                 TLR1 
                 toll-like receptor 1, mRNA [NM_003263] 
               
               
                 CD14 
                 CD14 molecule, mRNA [NM_001174104] 
               
               
                 SPC25 
                 SPC25, NDC80 kinetochore complex component,  
               
               
                   
                 mRNA [NM_020675] 
               
               
                 ASGR1 
                 asialoglycoprotein receptor 1, mRNA [AK308677,  
               
               
                   
                 NM_001671] 
               
               
                 STK26 
                 serine/threonine protein kinase MST4, mRNA  
               
               
                   
                 [NM_016542] 
               
               
                 EVI5 
                 ecotropic viral integration site 5, mRNA [NM_005665] 
               
               
                 SLC35B3 
                 solute carrier family 35 (adenosine 3′-phospho  
               
               
                   
                 5′-phosphosulfate transporter), member B3, mRNA  
               
               
                   
                 [NM_015948] 
               
               
                 FBXW2 
                 F-box and WD repeat domain containing 2, mRNA  
               
               
                   
                 [NM_012164] 
               
               
                 TLR6 
                 toll-like receptor 6, mRNA [NM_006068] 
               
               
                 EMILIN2 
                 elastin microfibril interfacer 2, mRNA [NM_032048] 
               
               
                 CCNB1 
                 cyclin B1, mRNA [NM_031966] 
               
               
                 HLA-DRB1 
                 major histocompatibility complex, class II, DR beta 1,  
               
               
                   
                 mRNA [NM_002124] 
               
               
                 GAS1 
                 growth arrest-specific 1, mRNA [NM_002048] 
               
               
                 RNASE2 
                 ribonuclease, RNase A family, 2 (liver, eosinophil- 
               
               
                   
                 derived neurotoxin), mRNA [NM_002934] 
               
               
                 CTSH 
                 cathepsin H, mRNA [NM_004390] 
               
               
                 PILRA 
                 paired immunoglobin-like type 2 receptor alpha,  
               
               
                   
                 mRNA [NM_178273] 
               
               
                 S1PR3 
                 sphingosine-1-phosphate receptor 3, mRNA  
               
               
                   
                 [NM_005226] 
               
               
                 TNF 
                 tumor necrosis factor, mRNA [NM_000594] 
               
               
                 IL1RN 
                 interleukin 1 receptor antagonist, mRNA  
               
               
                   
                 [NM_173843] 
               
               
                 CEP55 
                 centrosomal protein 55 kDa, mRNA [NM_018131] 
               
               
                 ECT2 
                 epithelial cell transforming sequence 2 oncogene,  
               
               
                   
                 mRNA [NM_018098] 
               
               
                 AQP9 
                 aquaporin 9, mRNA [NM_020980] 
               
               
                 NDUFAB1 
                 NADH dehydrogenase (ubiquinone) 1, alpha/beta  
               
               
                   
                 subcomplex, 1, 8 kDa, mRNA [NM_005003] 
               
               
                 SLA 
                 Src-like-adaptor, mRNA [NM_001045556] 
               
               
                 FES 
                 feline sarcoma oncogene, mRNA [NM_002005] 
               
               
                 HSPA6 
                 heat shock 70 kDa protein 6 (HSP70B′), mRNA  
               
               
                   
                 [NM_002155] 
               
               
                 RNF130 
                 ring finger protein 130, mRNA [NM_018434,  
               
               
                   
                 NM_001280801] 
               
               
                 CEP120 
                 centrosomal protein 120 kDa, mRNA [CR627324,  
               
               
                   
                 NM_153223] 
               
               
                 PNPLA8 
                 patatin-like phospholipase domain containing 8,  
               
               
                   
                 mRNA [NM_015723] 
               
               
                 HLA-DRB4 
                 major histocompatibility complex, class II, DR beta 4,  
               
               
                   
                 mRNA [NM_021983] 
               
               
                 ZBED5 
                 zinc finger, BED-type containing 5, mRNA  
               
               
                   
                 [NM_021211] 
               
               
                 RANBP1 
                 RAN binding protein 1, mRNA [NM_002882] 
               
               
                 MORF4L2 
                 mortality factor 4 like 2, mRNA [NM_012286] 
               
               
                 PADI2 
                 peptidyl arginine deiminase, type II, mRNA  
               
               
                   
                 [NM_007365] 
               
               
                 TPX2 
                 TPX2, microtubule-associated, mRNA [NM_012112] 
               
               
                 NEK2 
                 NIMA-related kinase 2, mRNA [NM_002497] 
               
               
                 EPB42 
                 erythrocyte membrane protein band 4.2, mRNA  
               
               
                   
                 [NM_000119] 
               
               
                 ARMC1 
                 armadillo repeat containing 1, mRNA [NM_018120] 
               
               
                 SMARCA5 
                 SWI/SNF related, matrix associated, actin dependent  
               
               
                   
                 regulator of chromatin, subfamily a, member 5,  
               
               
                   
                 mRNA [NM_003601] 
               
               
                 CSF1R 
                 colony stimulating factor 1 receptor, mRNA  
               
               
                   
                 [NM_005211] 
               
               
                 ATP5J2 
                 ATP synthase, H+ transporting, mitochondrial Fo  
               
               
                   
                 complex, subunit F2, mRNA [NM_004889,  
               
               
                   
                 NM_001003714] 
               
               
                 RPA3 
                 replication protein A3, 14 kDa, mRNA [NM_002947] 
               
               
                 SMARCD3 
                 SWI/SNF related, matrix associated, actin dependent  
               
               
                   
                 regulator of chromatin, subfamily d, member 3, mRNA  
               
               
                   
                 [NM_003078] 
               
               
                 EIF3K 
                 eukaryotic translation initiation factor 3, subunit K,  
               
               
                   
                 mRNA [NM_013234] 
               
               
                 GPR56 
                 G protein-coupled receptor 56, mRNA [NM_201525] 
               
               
                 ATP5I 
                 ATP synthase, H+ transporting, mitochondrial Fo  
               
               
                   
                 complex, subunit E, mRNA [NM_007100] 
               
               
                 NIF3L1 
                 NIF3 NGG1 interacting factor 3-like 1 ( S. cerevisiae ),  
               
               
                   
                 mRNA [NM_021824, NM_001142356] 
               
               
                 CD53 
                 CD53 molecule, mRNA [NM_001040033] 
               
               
                 MGST1 
                 microsomal glutathione S-transferase 1, mRNA  
               
               
                   
                 [NM_145791] 
               
               
                 COX7A2L 
                 cytochrome c oxidase subunit VIIa polypeptide 2 like,  
               
               
                   
                 mRNA [NM_004718] 
               
               
                 FCGR1B 
                 Fc fragment of IgG, high affinity Ib, receptor (CD64),  
               
               
                   
                 mRNA [NM_001244910, NM_001017986] 
               
               
                 KCNE3 
                 potassium voltage-gated channel, Isk-related family,  
               
               
                   
                 member 3, mRNA [NM_005472] 
               
               
                 XPO1 
                 exportin 1 (CRM1 homolog, yeast), mRNA  
               
               
                   
                 [NM_003400] 
               
               
                 PDE6D 
                 phosphodiesterase 6D, cGMP-specific, rod, delta,  
               
               
                   
                 mRNA [NM_002601] 
               
               
                 MS4A6A 
                 membrane-spanning 4-domains, subfamily A, member  
               
               
                   
                 6A, mRNA [NM_152852, NM_022349] 
               
               
                 FBL 
                 fibrillarin, mRNA [NM_001436] 
               
               
                 SIRPB1 
                 signal-regulatory protein beta 1, mRNA  
               
               
                   
                 [NM_001135844, XM_006710250, NM_006065] 
               
               
                 RAD51 
                 RAD51 recombinase, mRNA [NM_002875] 
               
               
                 PLBD1 
                 phospholipase B domain containing 1, mRNA  
               
               
                   
                 [NM_024829] 
               
               
                 LAT2 
                 linker for activation of T cells family, member 2,  
               
               
                   
                 mRNA [NM_032464, XM_005250562] 
               
               
                 LILRB3 
                 leukocyte immunoglobulin-like receptor, subfamily B  
               
               
                   
                 (with TM and ITIM domains), member 3, mRNA  
               
               
                   
                 [NM_006864] 
               
               
                 LILRA5 
                 leukocyte immunoglobulin-like receptor, subfamily A  
               
               
                   
                 (with TM domain), member 5, mRNA [NM_181879] 
               
               
                 PRIM1 
                 primase, DNA, polypeptide 1 (49 kDa), mRNA  
               
               
                   
                 [NM_000946] 
               
               
                 CFD 
                 complement factor D (adipsin), mRNA [NM_001928] 
               
               
                 NCF2 
                 neutrophil cytosolic factor 2, mRNA [NM_000433] 
               
               
                 NDUFA2 
                 NADH dehydrogenase (ubiquinone) 1 alpha  
               
               
                   
                 subcomplex, 2, 8 kDa, mRNA [NM_002488] 
               
               
                 SMPDL3A 
                 sphingomyelin phosphodiesterase, acid-like 3A,  
               
               
                   
                 mRNA [NM_006714] 
               
               
                 AGTRAP 
                 angiotensin II receptor-associated protein, mRNA  
               
               
                   
                 [NM_001040196] 
               
               
                 GIMAP7 
                 GTPase, IMAP family member 7, mRNA  
               
               
                   
                 [NM_153236] 
               
               
                 IRAK3 
                 interleukin-1 receptor-associated kinase 3, mRNA  
               
               
                   
                 [NM_007199] 
               
               
                 ASGR2 
                 asialoglycoprotein receptor 2, mRNA [NM_080912] 
               
               
                 UQCRC1 
                 ubiquinol-cytochrome c reductase core protein I,  
               
               
                   
                 mRNA [NM_003365] 
               
               
                 CD36 
                 CD36 molecule (thrombospondin receptor), mRNA  
               
               
                   
                 [NM_001001547] 
               
               
                 CD33 
                 CD33 molecule, mRNA [NM_001772,  
               
               
                   
                 NM_001177608] 
               
               
                 PSAP 
                 prosaposin, mRNA [NM_001042465] 
               
               
                 RAD51C 
                 RAD51 paralog C, mRNA [NM_002876] 
               
               
                 LCP1 
                 lymphocyte cytosolic protein 1 (L-plastin), mRNA  
               
               
                   
                 [NM_002298] 
               
               
                 BCL6 
                 B-cell CLL/lymphoma 6, mRNA [NM_001130845] 
               
               
                 LILRA6 
                 leukocyte immunoglobulin-like receptor, subfamily B  
               
               
                   
                 (with TM and ITIM domains), member 3, mRNA  
               
               
                   
                 [NR_104098, NM_024318] 
               
               
                 CCT8 
                 chaperonin containing TCP1, subunit 8 (theta), mRNA  
               
               
                   
                 [NM_006585] 
               
               
                 ACSL1 
                 acyl-CoA synthetase long-chain family member 1,  
               
               
                   
                 mRNA [NM_001995] 
               
               
                 HCLS1 
                 hematopoietic cell-specific Lyn substrate 1, mRNA  
               
               
                   
                 [NM_005335] 
               
               
                 ITGA4 
                 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of  
               
               
                   
                 VLA-4 receptor), mRNA [NM_000885] 
               
               
                 SULF2 
                 sulfatase 2, mRNA [NM_018837] 
               
               
                 CRTAM 
                 cytotoxic and regulatory T cell molecule, mRNA  
               
               
                   
                 [NM_019604] 
               
               
                 CCT4 
                 chaperonin containing TCP1, subunit 4 (delta), mRNA  
               
               
                   
                 [NM_006430] 
               
               
                 CHRDL1 
                 chordin-like 1, mRNA [NM_145234, NM_001143981] 
               
               
                 GZMA 
                 granzyme A (granzyme 1, cytotoxic T-lymphocyte- 
               
               
                   
                 associated serine esterase 3), mRNA [NM_006144] 
               
               
                 PGD 
                 phosphogluconate dehydrogenase, mRNA  
               
               
                   
                 [NM_002631] 
               
               
                 ARID4B 
                 AT rich interactive domain 4B (RBP1-like), mRNA  
               
               
                   
                 [NM_016374, AB030181] 
               
               
                 RFC4 
                 replication factor C (activator 1) 4, 37 kDa, mRNA  
               
               
                   
                 [NM_002916] 
               
               
                 TNFRSF10B  
                 tumor necrosis factor receptor superfamily, member  
               
               
                   
                 10b, mRNA [NM_003842] 
               
               
                 POLD3 
                 polymerase (DNA-directed), delta 3, accessory subunit,  
               
               
                   
                 mRNA [NM_006591] 
               
               
                 UQCRFS1 
                 ubiquinol-cytochrome c reductase, Rieske iron-sulfur  
               
               
                   
                 polypeptide 1, mRNA [NM_006003] 
               
               
                 ROCK1 
                 Rho-associated, coiled-coil containing protein kinase 1,  
               
               
                   
                 mRNA [NM_005406] 
               
               
                 NDUFS3 
                 NADH dehydrogenase (ubiquinone) Fe—S protein 3,  
               
               
                   
                 30 kDa (NADH-coenzyme Q reductase), mRNA  
               
               
                   
                 [NM_004551] 
               
               
                 CCT3 
                 chaperonin containing TCP1, subunit 3 (gamma),  
               
               
                   
                 mRNA [NM_005998] 
               
               
                 HLA-DMA 
                 major histocompatibility complex, class II, DM alpha,  
               
               
                   
                 mRNA [NM_006120] 
               
               
                 GP9 
                 glycoprotein IX (platelet), mRNA [NM_000174] 
               
               
                 MYD88 
                 myeloid differentiation primary response 88, mRNA  
               
               
                   
                 [NM_002468] 
               
               
                 SH2D1A 
                 SH2 domain containing 1A, mRNA [NM_001114937,  
               
               
                   
                 NM_002351] 
               
               
                 NCF1 
                 neutrophil cytosolic factor 1, mRNA [NM_000265] 
               
               
                 CD27 
                 CD27 molecule, mRNA [NM_001242] 
               
               
                 SPRY4 
                 sprouty homolog 4 ( Drosophila ), mRNA  
               
               
                   
                 [NM_001293289, NM_030964] 
               
               
                 NLGN1 
                 neuroligin 1, mRNA [NM_014932] 
               
               
                 HPSE 
                 heparanase, mRNA [NM_006665] 
               
               
                 MED23 
                 mediator complex subunit 23, mRNA  
               
               
                   
                 [NM_001270522, AF104255, NM_015979,  
               
               
                   
                 NM_004830] 
               
               
                 UBE2T 
                 ubiquitin-conjugating enzyme E2T (putative), mRNA  
               
               
                   
                 [NM_014176] 
               
               
                 LILRA2 
                 leukocyte immunoglobulin-like receptor, subfamily A  
               
               
                   
                 (with TM domain), member 2, mRNA [NM_006866] 
               
               
                 LEF1 
                 lymphoid enhancer-binding factor 1, mRNA  
               
               
                   
                 [NM_016269] 
               
               
                 KNTC1 
                 kinetochore associated 1, mRNA [NM_014708] 
               
               
                 ACPP 
                 acid phosphatase, prostate, mRNA [NM_001099] 
               
               
                 APOBEC3A 
                 apolipoprotein B mRNA editing enzyme, catalytic  
               
               
                   
                 polypeptide-like 3A, mRNA [NM_145699] 
               
               
                 GOLPH3L 
                 golgi phosphoprotein 3-like, mRNA [NM_018178] 
               
               
                 UQCRH 
                 ubiquinol-cytochrome c reductase hinge protein,  
               
               
                   
                 mRNA [NM_006004, NM_001297565] 
               
               
                 SLC7A7 
                 solute carrier family 7 (amino acid transporter light  
               
               
                   
                 chain, y + L system), member 7, mRNA  
               
               
                   
                 [NM_001126106] 
               
               
                 FGFBP2 
                 fibroblast growth factor binding protein 2, mRNA  
               
               
                   
                 [NM_031950] 
               
               
                 TMPO 
                 thymopoietin, mRNA [NM_003276, NM_001032283] 
               
               
                 CEP76 
                 centrosomal protein 76 kDa, mRNA [NM_024899] 
               
               
                 CPVL 
                 carboxypeptidase, vitellogenic-like, mRNA  
               
               
                   
                 [NM_019029] 
               
               
                 IL10RA 
                 interleukin 10 receptor, alpha, mRNA [NM_001558] 
               
               
                 TYMS 
                 thymidylate synthetase, mRNA [NM_001071] 
               
               
                 TSN 
                 translin, mRNA [NM_004622] 
               
               
                 CDC25A 
                 cell division cycle 25A, mRNA [NM_001789] 
               
               
                 CKS1B 
                 CDC28 protein kinase regulatory subunit 1B, mRNA  
               
               
                   
                 [NM_001826] 
               
               
                 GPR171 
                 G protein-coupled receptor 171, mRNA [NM_013308] 
               
               
                 POLA2 
                 polymerase (DNA directed), alpha 2, accessory  
               
               
                   
                 subunit, mRNA [AK307831] 
               
               
                 CLK1 
                 CDC-like kinase 1, mRNA [NM_004071,  
               
               
                   
                 NM_001162407] 
               
               
                 RAN 
                 RAN, member RAS oncogene family, mRNA  
               
               
                   
                 [NM_006325] 
               
               
                 F5 
                 coagulation factor V (proaccelerin, labile factor),  
               
               
                   
                 mRNA [NM_000130] 
               
               
                 CD2 
                 CD2 molecule, mRNA [AK310676, NM_001767] 
               
               
                 NDUFA8 
                 NADH dehydrogenase (ubiquinone) 1 alpha  
               
               
                   
                 subcomplex, 8, 19 kDa, mRNA [NM_014222] 
               
               
                 RBM47 
                 RNA binding motif protein 47, mRNA [NM_019027] 
               
               
                 CST3 
                 cystatin C, mRNA [NM_001288614, NM_000099] 
               
               
                 NDUFA11 
                 NADH dehydrogenase (ubiquinone) 1 alpha  
               
               
                   
                 subcomplex, 11, 14.7 kDa, mRNA [NM_175614] 
               
               
                 SKA3 
                 spindle and kinetochore associated complex subunit 3,  
               
               
                   
                 mRNA [NM_145061] 
               
               
                 EIF3D 
                 eukaryotic translation initiation factor 3, subunit D,  
               
               
                   
                 mRNA [NM_003753] 
               
               
                 FHL2 
                 four and a half LIM domains 2, mRNA [CR936682,  
               
               
                   
                 NM_001039492, NM_201555] 
               
               
                 MAFB 
                 v-maf avian musculoaponeurotic fibrosarcoma  
               
               
                   
                 oncogene homolog B, mRNA [NM_005461] 
               
               
                 TLK1 
                 tousled-like kinase 1, mRNA [NM_012290] 
               
               
                 CHAC2 
                 ChaC, cation transport regulator homolog 2 ( E. coli ),  
               
               
                   
                 mRNA [NM_001008708] 
               
               
                 RAB21 
                 RAB21, member RAS oncogene family, mRNA  
               
               
                   
                 [NM_014999] 
               
               
                 COX6B1 
                 cytochrome c oxidase subunit VIb polypeptide 1  
               
               
                   
                 (ubiquitous), mRNA [NM_001863] 
               
               
                 GPR18 
                 G protein-coupled receptor 18, mRNA [NM_005292] 
               
               
                 SLAMF1 
                 signaling lymphocytic activation molecule family  
               
               
                   
                 member 1, mRNA [NM_003037] 
               
               
                 NUP88 
                 nucleoporin 88 kDa, mRNA [NM_002532] 
               
               
                 UQCRC2 
                 ubiquinol-cytochrome c reductase core protein II,  
               
               
                   
                 mRNA [NM_003366] 
               
               
                 BRCA1 
                 breast cancer 1, early onset, mRNA [NM_007300] 
               
               
                 CYFIP1 
                 cytoplasmic FMR1 interacting protein 1, mRNA  
               
               
                   
                 [NM_014608] 
               
               
                 TMOD1 
                 tropomodulin 1, mRNA [NM_003275] 
               
               
                 TIPIN 
                 TIMELESS interacting protein, mRNA [NM_017858] 
               
               
                 COX8A 
                 cytochrome c oxidase subunit VIIIA (ubiquitous),  
               
               
                   
                 mRNA [NM_004074] 
               
               
                 LILRB2 
                 leukocyte immunoglobulin-like receptor, subfamily B  
               
               
                   
                 (with TM and ITIM domains), member 2, mRNA  
               
               
                   
                 [NM_005874] 
               
               
                 RFC2 
                 replication factor C (activator 1) 2, 40 kDa, mRNA  
               
               
                   
                 [NM_181471] 
               
               
                 IL13RA1 
                 interleukin 13 receptor, alpha 1, mRNA [NM_001560] 
               
               
                 CD300LF 
                 CD300 molecule-like family member f, mRNA  
               
               
                   
                 [NM_139018] 
               
               
                 NCF4 
                 neutrophil cytosolic factor 4, 40 kDa, mRNA  
               
               
                   
                 [NM_000631] 
               
               
                 RRM1 
                 ribonucleotide reductase M1, mRNA [NM_001033] 
               
               
                 ELAVL3 
                 ELAV like neuron-specific RNA binding protein 3,  
               
               
                   
                 mRNA [NM_001420] 
               
               
                 LTBR 
                 lymphotoxin beta receptor (TNFR superfamily,  
               
               
                   
                 member 3), mRNA [NM_002342] 
               
               
                 ALOX5 
                 arachidonate 5-lipoxygenase, mRNA [NM_000698,  
               
               
                   
                 AB208946] 
               
               
                 PLAUR 
                 plasminogen activator, urokinase receptor, mRNA  
               
               
                   
                 [NM_001005377] 
               
               
                 CRISPLD2 
                 cysteine-rich secretory protein LCCL domain  
               
               
                   
                 containing 2, mRNA [NM_031476] 
               
               
                 PYGL 
                 phosphorylase, glycogen, liver, mRNA [NM_002863] 
               
               
                 MDFIC 
                 MyoD family inhibitor domain containing, mRNA  
               
               
                   
                 [NM_199072, NM_001166346] 
               
               
                 CFP 
                 complement factor properdin, mRNA [NM_002621] 
               
               
                 KIF2C 
                 kinesin family member 2C, mRNA [NM_006845] 
               
               
                 HCK 
                 hemopoietic cell kinase, mRNA [NM_002110] 
               
               
                 THEMIS 
                 thymocyte selection associated, mRNA  
               
               
                   
                 [NM_001164685] 
               
               
                 KIAA1598 
                 KIAA1598, mRNA [NM_018330, NM_001127211,  
               
               
                   
                 NM_001258299] 
               
               
                 IL1R2 
                 interleukin 1 receptor, type II, mRNA [NM_004633] 
               
               
                 FAM83D 
                 family with sequence similarity 83, member D, mRNA  
               
               
                   
                 [NM_030919] 
               
               
                 CXCR2 
                 chemokine (C-X-C motif) receptor 2, mRNA  
               
               
                   
                 [NM_001557] 
               
               
                 RTN1 
                 reticulon 1, mRNA [NM_021136] 
               
               
                 TIMP2 
                 TIMP metallopeptidase inhibitor 2, mRNA  
               
               
                   
                 [NM_003255] 
               
               
                 GATA3 
                 GATA binding protein 3, mRNA [NM_001002295] 
               
               
                 UBA3 
                 ubiquitin-like modifier activating enzyme 3, mRNA  
               
               
                   
                 [NM_003968] 
               
               
                 PRRX1 
                 paired related homeobox 1, mRNA [NM_006902] 
               
               
                 NLRP3 
                 NLR family, pyrin domain containing 3, mRNA  
               
               
                   
                 [NM_001243133, NM_001079821] 
               
               
                 UHRF1 
                 ubiquitin-like with PHD and ring finger domains 1,  
               
               
                   
                 mRNA [NM_013282, NM_001290050] 
               
               
                 OIP5 
                 Opa interacting protein 5, mRNA [NM_007280] 
               
               
                 PAK1 
                 p21 protein (Cdc42/Rac)-activated kinase 1, mRNA  
               
               
                   
                 [NM_001128620] 
               
               
                 LY86 
                 lymphocyte antigen 86, mRNA [NM_004271] 
               
               
                 KLRD1 
                 killer cell lectin-like receptor subfamily D, member 1,  
               
               
                   
                 mRNA [NM_002262] 
               
               
                 DTL 
                 denticleless E3 ubiquitin protein ligase homolog  
               
               
                   
                 ( Drosophila ), mRNA [NM_016448] 
               
               
                 SIRPA 
                 signal-regulatory protein alpha, mRNA  
               
               
                   
                 [NM_001040022] 
               
               
                 TRAT1 
                 T cell receptor associated transmembrane adaptor 1,  
               
               
                   
                 mRNA [NM_016388] 
               
               
                 RASSF4 
                 Ras association (RalGDS/AF-6) domain family  
               
               
                   
                 member 4, mRNA [NM_032023] 
               
               
                 PECAM1 
                 platelet/endothelial cell adhesion molecule 1, mRNA  
               
               
                   
                 [NM_000442] 
               
               
                 RFC3 
                 replication factor C (activator 1) 3, 38 kDa, mRNA  
               
               
                   
                 [NM_002915, NM_181558] 
               
               
                 ACTL6A 
                 actin-like 6A, mRNA [AK223212] 
               
               
                 CHEK1 
                 checkpoint kinase 1, mRNA [NM_001114121] 
               
               
                 BUB1 
                 BUB1 mitotic checkpoint serine/threonine kinase,  
               
               
                   
                 mRNA [NM_004336] 
               
               
                 PYCARD 
                 PYD and CARD domain containing, mRNA  
               
               
                   
                 [NM_013258] 
               
               
                 EIF3F 
                 eukaryotic translation initiation factor 3, subunit F,  
               
               
                   
                 mRNA [NM_003754] 
               
               
                 ARHGEF10L 
                 Rho guanine nucleotide exchange factor (GEF) 10-like,  
               
               
                   
                 mRNA [NM_018125] 
               
               
                 ITM2A 
                 integral membrane protein 2A, mRNA [NM_004867] 
               
               
                 LILRB1 
                 leukocyte immunoglobulin-like receptor, subfamily B  
               
               
                   
                 (with TM and ITIM domains), member 1, mRNA  
               
               
                   
                 [NM_006669] 
               
               
                 NUP37 
                 nucleoporin 37 kDa, mRNA [NM_024057] 
               
               
                 GIMAP6 
                 GTPase, IMAP family member 6, mRNA  
               
               
                   
                 [NM_024711] 
               
               
                 EVI2B 
                 ecotropic viral integration site 2B, mRNA  
               
               
                   
                 [NM_006495] 
               
               
                 C1S 
                 complement component 1, s subcomponent, mRNA  
               
               
                   
                 [NM_201442, NM_001734] 
               
               
                 RASGRP1 
                 RAS guanyl releasing protein 1 (calcium and DAG- 
               
               
                   
                 regulated), mRNA [NM_005739] 
               
               
                 PRKAR2B 
                 protein kinase, cAMP-dependent, regulatory, type II,  
               
               
                   
                 beta, mRNA [NM_002736] 
               
               
                 AGPAT9 
                 1-acylglycerol-3-phosphate O-acyltransferase 9, mRNA  
               
               
                   
                 [NM_032717] 
               
               
                 FPR2 
                 formyl peptide receptor 2, mRNA [NM_001462] 
               
               
                 AURKB 
                 aurora kinase B, mRNA [NM_004217] 
               
               
                 TNFAIP2 
                 tumor necrosis factor, alpha-induced protein 2, mRNA  
               
               
                   
                 [NM_006291] 
               
               
                 NUP62 
                 nucleoporin 62 kDa, mRNA [NM_153719,  
               
               
                   
                 NM_016553] 
               
               
                 EIF3G 
                 eukaryotic translation initiation factor 3, subunit G,  
               
               
                   
                 mRNA [NM_003755] 
               
               
                 GOPC 
                 golgi-associated PDZ and coiled-coil motif containing,  
               
               
                   
                 mRNA [NM_020399] 
               
               
                 CCT7 
                 chaperonin containing TCP1, subunit 7 (eta), mRNA  
               
               
                   
                 [NM_006429] 
               
               
                 IMPA2 
                 inositol(myo)-1(or 4)-monophosphatase 2, mRNA  
               
               
                   
                 [NM_014214] 
               
               
                 UPF3B 
                 UPF3 regulator of nonsense transcripts homolog B  
               
               
                   
                 (yeast), mRNA [NM_080632] 
               
               
                 SACM1L 
                 SAC1 suppressor of actin mutations 1-like (yeast),  
               
               
                   
                 mRNA [NM_014016] 
               
               
                 CSF3R 
                 colony stimulating factor 3 receptor (granulocyte),  
               
               
                   
                 mRNA [NM_156039] 
               
               
                 PVRIG 
                 poliovirus receptor related immunoglobulin domain  
               
               
                   
                 containing, mRNA [NM_024070] 
               
               
                 RAD54L 
                 RAD54-like ( S. cerevisiae ), mRNA [NM_003579] 
               
               
                 ATP9A 
                 ATPase, class II, type 9A, mRNA [NM_006045] 
               
               
                 NDUFB4 
                 NADH dehydrogenase (ubiquinone) 1 beta  
               
               
                   
                 subcomplex, 4, 15 kDa, mRNA [NM_004547] 
               
               
                 HOMER3 
                 homer homolog 3 ( Drosophila ), mRNA  
               
               
                   
                 [NM_001145722, NM_001145724, NM_004838] 
               
               
                 TNS3 
                 tensin 3, mRNA [NM_022748] 
               
               
                 NLRP12 
                 NLR family, pyrin domain containing 12, mRNA  
               
               
                   
                 [NM_001277126] 
               
               
                 ADRB2 
                 adrenoceptor beta 2, surface, mRNA [NM_000024] 
               
               
                 NUP43 
                 nucleoporin 43 kDa, mRNA [NM_198887] 
               
               
                 CCT6A 
                 chaperonin containing TCP1, subunit 6A (zeta 1),  
               
               
                   
                 mRNA [NM_001762] 
               
               
                 TLR2 
                 toll-like receptor 2, mRNA [NM_003264] 
               
               
                 FAM72A  
                 family with sequence similarity 72, member A, mRNA  
               
               
                   
                 [NM_001123168] 
               
               
                 SERPINA1 
                 serpin peptidase inhibitor, clade A (alpha-1  
               
               
                   
                 antiproteinase, antitrypsin), member 1, mRNA  
               
               
                   
                 [NM_001002236, BX248257] 
               
               
                 SLC24A4 
                 solute carrier family 24 (sodium/potassium/calcium  
               
               
                   
                 exchanger), member 4, mRNA [NM_153647,  
               
               
                   
                 NM_153646] 
               
               
                 GLT1D1 
                 glycosyltransferase 1 domain containing 1, mRNA  
               
               
                   
                 [NM_144669] 
               
               
                 HSD17B4 
                 hydroxysteroid (17-beta) dehydrogenase 4, mRNA  
               
               
                   
                 [NM_000414] 
               
               
                 UXT 
                 ubiquitously-expressed, prefoldin-like chaperone,  
               
               
                   
                 mRNA [NM_004182] 
               
               
                 CEBPA 
                 CCAAT/enhancer binding protein (C/EBP), alpha,  
               
               
                   
                 mRNA [NM_004364] 
               
               
                 FCGR2C 
                 Fc fragment of IgG, low affinity IIa, receptor (CD32),  
               
               
                   
                 mRNA [NM_201563] 
               
               
                 PTPRC 
                 protein tyrosine phosphatase, receptor type, C, mRNA  
               
               
                   
                 [NR_052021, NM_002838] 
               
               
                 KLRK1 
                 killer cell lectin-like receptor subfamily K, member 1,  
               
               
                   
                 mRNA [NM_007360] 
               
               
                 CX3CR1 
                 chemokine (C-X3-C motif) receptor 1, mRNA  
               
               
                   
                 [NM_001337] 
               
               
                 LYL1 
                 lymphoblastic leukemia derived sequence 1, mRNA  
               
               
                   
                 [NM_005583] 
               
               
                 C7 
                 complement component 7, mRNA [NM_000587] 
               
               
                 BCL2 
                 B-cell CLL/lymphoma 2, mRNA [NM_000633,  
               
               
                   
                 NM_000657] 
               
               
                 MBOAT7 
                 membrane bound O-acyltransferase domain containing  
               
               
                   
                 7, mRNA [NM_024298, NM_001146082] 
               
               
                 KIR2DL5A 
                 killer cell immunoglobulin-like receptor, two domains,  
               
               
                   
                 long cytoplasmic tail, 5A, mRNA [NM_020535] 
               
               
                 MELK 
                 maternal embryonic leucine zipper kinase, mRNA  
               
               
                   
                 [NM_014791] 
               
               
                 CTNNA1 
                 catenin (cadherin-associated protein), alpha 1, 102 kDa,  
               
               
                   
                 mRNA [NM_001903] 
               
               
                 PLXNB2 
                 plexin B2, mRNA [NM_012401] 
               
               
                 SELL 
                 selectin L, mRNA [NM_000655] 
               
               
                 CRYBB3 
                 crystallin, beta B3, mRNA [NM_004076] 
               
               
                 KLRF1 
                 killer cell lectin-like receptor subfamily F, member 1,  
               
               
                   
                 mRNA [NM_001291823, NM_016523] 
               
               
                 ANLN 
                 anillin, actin binding protein, mRNA [NM_018685] 
               
               
                 NDUFC2 
                 NADH dehydrogenase (ubiquinone) 1, subcomplex  
               
               
                   
                 unknown, 2, 14.5 kDa, mRNA [NM_004549,  
               
               
                   
                 NM_001204054] 
               
               
                 PLK4 
                 polo-like kinase 4, mRNA [NM_014264] 
               
               
                 DOK2 
                 docking protein 2, 56 kDa, mRNA [NM_003974] 
               
               
                 DOK3 
                 docking protein 3, mRNA [NM_024872,  
               
               
                   
                 NM_001144875] 
               
               
                 TBCK 
                 TBC1 domain containing kinase, mRNA [NM_033115] 
               
               
                 PRKCH 
                 protein kinase C, eta, mRNA [NM_006255] 
               
               
                 CYC1 
                 cytochrome c-1, mRNA [NM_001916] 
               
               
                 ABLIM1 
                 actin binding LIM protein 1, mRNA [NM_001003408] 
               
               
                 EMR2 
                 egf-like module containing, mucin-like, hormone  
               
               
                   
                 receptor-like 2, mRNA [NM_013447] 
               
               
                 P2RY13 
                 purinergic receptor P2Y, G-protein coupled, 13, mRNA  
               
               
                   
                 [NM_176894] 
               
               
                 KIR3DL1 
                 killer cell immunoglobulin-like receptor, three  
               
               
                   
                 domains, long cytoplasmic tail, 1, mRNA  
               
               
                   
                 [NM_013289] 
               
               
                 CD163 
                 CD163 molecule, mRNA [NM_004244] 
               
               
                 CDCA7 
                 cell division cycle associated 7, mRNA [NM_031942] 
               
               
                 PDGFRA 
                 platelet-derived growth factor receptor, alpha  
               
               
                   
                 polypeptide, mRNA [NM_006206] 
               
               
                 CCL4L2 
                 chemokine (C-C motif) ligand 4, mRNA  
               
               
                   
                 [NM_001291470] 
               
               
                 HHEX 
                 hematopoietically expressed homeobox, mRNA  
               
               
                   
                 [NM_002729] 
               
               
                 KLRC3 
                 killer cell lectin-like receptor subfamily C, member 3,  
               
               
                   
                 mRNA [NM_007333] 
               
               
                 NDUFS7 
                 NADH dehydrogenase (ubiquinone) Fe—S protein 7,  
               
               
                   
                 20 kDa (NADH-coenzyme Q reductase), mRNA  
               
               
                   
                 [NM_024407] 
               
               
                 GINS4 
                 GINS complex subunit 4 (Sld5 homolog), mRNA  
               
               
                   
                 [NM_032336] 
               
               
                 PRAM1 
                 PML-RARA regulated adaptor molecule 1, mRNA  
               
               
                   
                 [NM_032152] 
               
               
                 IFNGR2 
                 interferon gamma receptor 2 (interferon gamma  
               
               
                   
                 transducer 1), mRNA [NM_005534] 
               
               
                 KIAA0513  
                 KIAA0513, mRNA [NM_014732] 
               
               
                 SPI1 
                 spleen focus forming virus (SFFV) proviral integration  
               
               
                   
                 oncogene, mRNA [NM_001080547] 
               
               
                 POC1A 
                 POC centriolar protein A, mRNA [NM_015426] 
               
               
                 DONSON 
                 downstream neighbor of SON, mRNA [NM_017613] 
               
               
                 MEGF9 
                 multiple EGF-like-domains 9, mRNA  
               
               
                   
                 [NM_001080497] 
               
               
                 CDC25C 
                 cell division cycle 25 C, mRNA [NM_001790] 
               
               
                 PTGER2 
                 prostaglandin E receptor 2 (subtype EP2), 53 kDa,  
               
               
                   
                 mRNA [NM_000956] 
               
               
                 CDCA8 
                 cell division cycle associated 8, mRNA [NM_018101] 
               
               
                 UQCR10 
                 ubiquinol-cytochrome c reductase, complex III subunit  
               
               
                   
                 X, mRNA [NM_013387, NM_001003684] 
               
               
                 COPB2 
                 coatomer protein complex, subunit beta 2 (beta prime),  
               
               
                   
                 mRNA [NM_004766] 
               
               
                 ALDH2 
                 aldehyde dehydrogenase 2 family (mitochondrial),  
               
               
                   
                 mRNA [NM_000690] 
               
               
                 RNASE6 
                 ribonuclease, RNase A family, k6, mRNA  
               
               
                   
                 [NM_005615] 
               
               
                 STAT4 
                 signal transducer and activator of transcription 4,  
               
               
                   
                 mRNA [NM_003151] 
               
               
                 SLC15A3 
                 solute carrier family 15 (oligopeptide transporter),  
               
               
                   
                 member 3, mRNA [NM_016582] 
               
               
                 SLC35A5 
                 solute carrier family 35, member A5, mRNA  
               
               
                   
                 [NM_017945] 
               
               
                 PLK1 
                 polo-like kinase 1, mRNA [AB084459, AK310544] 
               
               
                 SMC1A 
                 structural maintenance of chromosomes 1A, mRNA  
               
               
                   
                 [NM_006306, NM_001281463] 
               
               
                 CDK1 
                 cyclin-dependent kinase 1, mRNA [NM_001786] 
               
               
                 FBP1 
                 fructose-1,6-bisphosphatase 1, mRNA [NM_000507] 
               
               
                 CLIC3 
                 chloride intracellular channel 3, mRNA [NM_004669] 
               
               
                 ETV1 
                 ets variant 1, mRNA [NM_004956] 
               
               
                 MYO1F 
                 myosin IF, mRNA [NM_012335] 
               
               
                 S100A11 
                 S100 calcium binding protein A11, mRNA  
               
               
                   
                 [NM_005620] 
               
               
                 PIKFYVE 
                 phosphoinositide kinase, FYVE finger containing,  
               
               
                   
                 mRNA [NM_001178000, NM_015040] 
               
               
                 MYOF 
                 myoferlin, mRNA [NM_133337, NM_013451] 
               
               
                 AOAH 
                 acyloxyacyl hydrolase (neutrophil), mRNA  
               
               
                   
                 [NM_001637] 
               
               
                 CD3D 
                 CD3d molecule, delta (CD3-TCR complex), mRNA  
               
               
                   
                 [NM_000732] 
               
               
                 TMTC2 
                 transmembrane and tetratricopeptide repeat containing  
               
               
                   
                 2, mRNA [NM_152588] 
               
               
                 SUCLG1 
                 succinate-CoA ligase, alpha subunit, mRNA  
               
               
                   
                 [NM_003849] 
               
               
                 PTGDR 
                 prostaglandin D2 receptor (DP), mRNA [NM_000953] 
               
               
                 TREM1 
                 triggering receptor expressed on myeloid cells 1,  
               
               
                   
                 mRNA [NM_018643, NM_001242589] 
               
               
                 FCGRT 
                 Fc fragment of IgG, receptor, transporter, alpha, mRNA  
               
               
                   
                 [NM_004107] 
               
               
                 NUP133 
                 nucleoporin 133 kDa, mRNA [BX387507,  
               
               
                   
                 NM_018230] 
               
               
                 ACBD3 
                 acyl-CoA binding domain containing 3, mRNA  
               
               
                   
                 [NM_022735] 
               
               
                 CD8B 
                 CD8b molecule, mRNA [NM_172102, NM_004931] 
               
               
                 HELLS 
                 helicase, lymphoid-specific, mRNA [NM_018063,  
               
               
                   
                 NM_001289072] 
               
               
                 NFIA 
                 nuclear factor I/A, mRNA [NM_005595,  
               
               
                   
                 NM_001134673] 
               
               
                 PTPN11 
                 protein tyrosine phosphatase, non-receptor type 11,  
               
               
                   
                 mRNA [NM_002834] 
               
               
                 PRF1 
                 perforin 1 (pore forming protein), mRNA  
               
               
                   
                 [NM_005041] 
               
               
                 NCAM1 
                 neural cell adhesion molecule 1, mRNA  
               
               
                   
                 [NM_001076682, NM_001242608, NM_001242607] 
               
               
                 CYBB 
                 cytochrome b-245, beta polypeptide, mRNA  
               
               
                   
                 [NM_000397] 
               
               
                 SYK 
                 spleen tyrosine kinase, mRNA [NM_003177] 
               
               
                 TBXAS1 
                 thromboxane A synthase 1 (platelet), mRNA  
               
               
                   
                 [NM_001166254, NM_030984] 
               
               
                 ZAP70 
                 zeta-chain (TCR) associated protein kinase 70 kDa,  
               
               
                   
                 mRNA [NM_001079] 
               
               
                 SEMA4A 
                 sema domain, immunoglobulin domain (Ig),  
               
               
                   
                 transmembrane domain (TM) and short cytoplasmic  
               
               
                   
                 domain, (semaphorin) 4A, mRNA [NM_022367] 
               
               
                 LYN 
                 v-yes-1 Yamaguchi sarcoma viral related oncogene  
               
               
                   
                 homolog, mRNA [NM_002350] 
               
               
                 TRIM10 
                 tripartite motif containing 10, mRNA [NM_006778,  
               
               
                   
                 NM_052828] 
               
               
                 HJURP 
                 Holliday junction recognition protein, mRNA  
               
               
                   
                 [NM_018410] 
               
               
                 PRKCD 
                 protein kinase C, delta, mRNA [NM_006254] 
               
               
                 KIF11 
                 kinesin family member 11, mRNA [NM_004523] 
               
               
                 RHOH 
                 ras homolog family member H, mRNA [NM_004310] 
               
               
                 GRN 
                 granulin, mRNA [NM_002087] 
               
               
                 TTC1 
                 tetratricopeptide repeat domain 1, mRNA  
               
               
                   
                 [NM_003314] 
               
               
                 ITGAM 
                 integrin, alpha M (complement component 3 receptor 3  
               
               
                   
                 subunit), mRNA [NM_000632] 
               
               
                 RXRA 
                 retinoid X receptor, alpha, mRNA [NM_002957] 
               
               
                 NUP85 
                 nucleoporin 85 kDa, mRNA [NM_024844] 
               
               
                 XCL1 
                 chemokine (C motif) ligand 1, mRNA [NM_002995] 
               
               
                 BTK 
                 Bruton agammaglobulinemia tyrosine kinase, mRNA  
               
               
                   
                 [NM_001287344, NM_000061] 
               
               
                 KIR2DS4 
                 killer cell immunoglobulin-like receptor, two domains,  
               
               
                   
                 short cytoplasmic tail, 4, mRNA [NM_012314] 
               
               
                 GINS2 
                 GINS complex subunit 2 (Psf2 homolog), mRNA  
               
               
                   
                 [NM_016095] 
               
               
                 CARD11 
                 caspase recruitment domain family, member 11, mRNA  
               
               
                   
                 [NM_032415, AK097139] 
               
               
                 NUP205 
                 nucleoporin 205 kDa, mRNA [NM_015135] 
               
               
                 COX5A 
                 cytochrome c oxidase subunit Va, mRNA  
               
               
                   
                 [NM_004255] 
               
               
                 IL12RB2 
                 interleukin 12 receptor, beta 2, mRNA [NM_001559] 
               
               
                 ITGB2 
                 integrin, beta 2 (complement component 3 receptor 3  
               
               
                   
                 and 4 subunit), mRNA [L78790, NM_000211] 
               
               
                 FXYD6 
                 FXYD domain containing ion transport regulator 6,  
               
               
                   
                 mRNA [NM_022003] 
               
               
                 NKG7 
                 natural killer cell group 7 sequence, mRNA  
               
               
                   
                 [NM_005601] 
               
               
                 CLEC12B 
                 C-type lectin domain family 12, member B, mRNA  
               
               
                   
                 [NM_205852, NM_001129998] 
               
               
                 TBX21 
                 T-box 21, mRNA [NM_013351] 
               
               
                 TMEM106C 
                 transmembrane protein 106C, mRNA [NM_024056] 
               
               
                 EOMES 
                 eomesodermin, mRNA [NM_005442] 
               
               
                 CPPED1 
                 calcineurin-like phosphoesterase domain containing 1,  
               
               
                   
                 mRNA [NM_018340] 
               
               
                 HEPACAM2 
                 HEPACAM family member 2, mRNA  
               
               
                   
                 [NM_001039372] 
               
               
                 BMI1 
                 BMI1 polycomb ring finger oncogene, mRNA  
               
               
                   
                 [NM_005180] 
               
               
                 CST7 
                 cystatin F (leukocystatin), mRNA [NM_003650] 
               
               
                 KIR2DL2 
                 killer cell immunoglobulin-like receptor, two domains,  
               
               
                   
                 long cytoplasmic tail, 2, mRNA [NM_014219] 
               
               
                 PROS1 
                 protein S (alpha), mRNA [NM_000313] 
               
               
                 SLC28A1 
                 solute carrier family 28 (concentrative nucleoside  
               
               
                   
                 transporter), member 1, mRNA [NM_004213,  
               
               
                   
                 NM_201651] 
               
               
                 STEAP4 
                 STEAP family member 4, mRNA [NM_001205315] 
               
               
                 RORA 
                 RAR-related orphan receptor A, mRNA [NM_134260] 
               
               
                 MATK 
                 megakaryocyte-associated tyrosine kinase, mRNA  
               
               
                   
                 [NM_139355] 
               
               
                 TCF7 
                 transcription factor 7 (T-cell specific, HMG-box),  
               
               
                   
                 mRNA [NM_003202] 
               
               
                 MCTP1 
                 multiple C2 domains, transmembrane 1, mRNA  
               
               
                   
                 [NM_024717] 
               
               
                 CCNB2 
                 cyclin B2, mRNA [NM_004701] 
               
               
                 CCL5 
                 chemokine (C-C motif) ligand 5, mRNA [NM_002985] 
               
               
                 TRIP13 
                 thyroid hormone receptor interactor 13, mRNA  
               
               
                   
                 [NM_004237] 
               
               
                 TNFSF12 
                 tumor necrosis factor (ligand) superfamily, member 12,  
               
               
                   
                 mRNA [NM_003809] 
               
               
                 PDGFRB 
                 platelet derived growth factor receptor beta, mRNA  
               
               
                   
                 [NM_002609] 
               
               
                 NDUFB11 
                 NADH dehydrogenase (ubiquinone) 1 beta  
               
               
                   
                 subcomplex, 11, 17.3 kDa, mRNA [NM_019056] 
               
               
                 ELP4 
                 elongator acetyltransferase complex subunit 4, mRNA  
               
               
                   
                 [NM_019040] 
               
               
                 KLRC1 
                 killer cell lectin-like receptor subfamily C, member 1,  
               
               
                   
                 mRNA [NM_007328, NM_002259] 
               
               
                 PMS1 
                 PMS1 postmeiotic segregation increased 1  
               
               
                   
                 ( S. cerevisiae ), mRNA [NM_000534, NM_001128144] 
               
               
                 SCPEP1 
                 serine carboxypeptidase 1, mRNA [NM_021626] 
               
               
                 SP140 
                 SP140 nuclear body protein, mRNA [NM_001005176,  
               
               
                   
                 NM_007237] 
               
               
                 POLA1 
                 polymerase (DNA directed), alpha 1, catalytic subunit,  
               
               
                   
                 mRNA [NM_016937] 
               
               
                 FASLG 
                 Fas ligand (TNF superfamily, member 6), mRNA  
               
               
                   
                 [NM_000639] 
               
               
                 SLC35A3 
                 solute carrier family 35 (UDP-N-acetylglucosamine  
               
               
                   
                 (UDP-GlcNAc) transporter), member A3, mRNA  
               
               
                   
                 [NM_012243] 
               
               
                 SORT1 
                 sortilin 1, mRNA [NM_002959] 
               
               
                 ABCA8 
                 ATP-binding cassette, sub-family A (ABC1), member  
               
               
                   
                 8, mRNA [NM_007168] 
               
               
                 DTYMK 
                 deoxythymidylate kinase (thymidylate kinase), mRNA  
               
               
                   
                 [NM_012145] 
               
               
                 NOP56 
                 NOP56 ribonucleoprotein, mRNA [NM_006392] 
               
               
                 SMARCAL1 
                 SWI/SNF related, matrix associated, actin dependent  
               
               
                   
                 regulator of chromatin, subfamily a-like 1, mRNA  
               
               
                   
                 [NM_014140] 
               
               
                 PLEK 
                 pleckstrin, mRNA [NM_002664] 
               
               
                 SEH1L 
                 SEH1-like ( S. cerevisiae ), mRNA [NM_031216,  
               
               
                   
                 NM_001013437] 
               
               
                 ITK 
                 IL2-inducible T-cell kinase, mRNA [NM_005546] 
               
               
                 NFAM1 
                 NEAT activating protein with ITAM motif 1, mRNA  
               
               
                   
                 [NM_145912] 
               
               
                 ITPR3 
                 inositol 1,4,5-trisphosphate receptor, type 3, mRNA  
               
               
                   
                 [NM_002224] 
               
               
                 TNFRSF18  
                 tumor necrosis factor receptor superfamily, member 18,  
               
               
                   
                 mRNA [NM_148901] 
               
               
                 FCAR 
                 Fc fragment of IgA, receptor for, mRNA [NM_002000,  
               
               
                   
                 NM_133271] 
               
               
                 E2E7 
                 E2F transcription factor 7, mRNA [NM_203394] 
               
               
                 KCNQ1 
                 potassium voltage-gated channel, KQT-like subfamily,  
               
               
                   
                 member 1, mRNA [NM_000218] 
               
               
                 CENPW 
                 centromere protein W, mRNA [NM_001012507] 
               
               
                 SIGLEC7 
                 sialic acid binding Ig-like lectin 7, mRNA  
               
               
                   
                 [NM_014385] 
               
               
                 PCNA 
                 proliferating cell nuclear antigen, mRNA [NM_002592] 
               
               
                 ANO10 
                 anoctamin 10, mRNA [NM_001204831] 
               
               
                 PTPRE 
                 protein tyrosine phosphatase, receptor type, E, mRNA  
               
               
                   
                 [NM_006504] 
               
               
                 ABCC13 
                 ATP-binding cassette, sub-family C (CFTR/MRP),  
               
               
                   
                 member 13, pseudogene, mRNA [NR_003088,  
               
               
                   
                 NR_003087] 
               
               
                 TSNAX 
                 translin-associated factor X, mRNA [NM_005999] 
               
               
                 SSBP1 
                 single-stranded DNA binding protein 1, mitochondrial,  
               
               
                   
                 mRNA [NM_003143] 
               
               
                 TGFBR3 
                 transforming growth factor, beta receptor III, mRNA  
               
               
                   
                 [NM_003243] 
               
               
                 CENPE 
                 centromere protein E, 312 kDa, mRNA [NM_001813] 
               
               
                 NDUFS8 
                 NADH dehydrogenase (ubiquinone) Fe—S protein 8, 23  
               
               
                   
                 kDa (NADH-coenzyme Q reductase), mRNA  
               
               
                   
                 [NM_002496] 
               
               
                 CARD9 
                 caspase recruitment domain family, member 9, mRNA  
               
               
                   
                 [NM_052813, NM_052814] 
               
               
                 CHAF1B 
                 chromatin assembly factor 1, subunit B (p60), mRNA  
               
               
                   
                 [NM_005441] 
               
               
                 IL6R 
                 interleukin 6 receptor, mRNA [NM_000565,  
               
               
                   
                 NM_001206866] 
               
               
                 CD8A 
                 CD8a molecule, mRNA [NM_001768,  
               
               
                   
                 NM_001145873] 
               
               
                 CDCA5 
                 cell division cycle associated 5, mRNA [NM_080668] 
               
               
                 CEP72 
                 centrosomal protein 72 kDa, mRNA [NM_018140] 
               
               
                 KIAA1109  
                 KIAA1109, mRNA [NM_015312] 
               
               
                 H2AFX 
                 H2A histone family, member X, mRNA [NM_002105] 
               
               
                 HOPX 
                 HOP homeobox, mRNA [NM_001145460,  
               
               
                   
                 NM_139211] 
               
               
                 ARL4C 
                 ADP-ribosylation factor-like 4C, mRNA  
               
               
                   
                 [NM_001282431] 
               
               
                 TLR8 
                 toll-like receptor 8, mRNA [NM_016610] 
               
               
                 SLC16A3 
                 solute carrier family 16 (monocarboxylate transporter),  
               
               
                   
                 member 3, mRNA [NM_001042422] 
               
               
                 CD96 
                 CD96 molecule, mRNA [NM_198196] 
               
               
                 FMR1 
                 fragile X mental retardation 1, mRNA [NM_002024] 
               
               
                 CAMK4 
                 calcium/calmodulin-dependent protein kinase IV,  
               
               
                   
                 mRNA [NM_001744] 
               
               
                 CENPF 
                 centromere protein F, 350/400 kDa, mRNA  
               
               
                   
                 [NM_016343] 
               
               
                 ANP32E 
                 acidic (leucine-rich) nuclear phosphoprotein 32 family,  
               
               
                   
                 member E, mRNA [NM_030920] 
               
               
                 LCK 
                 lymphocyte-specific protein tyrosine kinase, mRNA  
               
               
                   
                 [NM_005356] 
               
               
                 KCTD12 
                 potassium channel tetramerization domain containing  
               
               
                   
                 12, mRNA [NM_138444] 
               
               
                 CASC5 
                 cancer susceptibility candidate 5, mRNA [NM_170589] 
               
               
                 SGOL2 
                 shugoshin-like 2 ( S. pombe ), mRNA [NM_152524] 
               
               
                 TNFRSF1B 
                 tumor necrosis factor receptor superfamily, member 1B,  
               
               
                   
                 mRNA [NM_001066] 
               
               
                 GZMM 
                 granzyme M (lymphocyte met-ase 1), mRNA  
               
               
                   
                 [NM_005317] 
               
               
                 IL7R 
                 interleukin 7 receptor, mRNA [NM_002185] 
               
               
                 MCM6 
                 minichromosome maintenance complex component 6,  
               
               
                   
                 mRNA [NM_005915] 
               
               
                 CD1D 
                 CD1d molecule, mRNA [NM_001766] 
               
               
                 ASPM 
                 asp (abnormal spindle) homolog, microcephaly  
               
               
                   
                 associated ( Drosophila ), mRNA [NM_018136] 
               
               
                 PAX2 
                 paired box 2, mRNA [NM_003990, NM_003988] 
               
               
                 ZMYM2 
                 zinc finger, MYM-type 2, mRNA [NM_003453,  
               
               
                   
                 AL136621] 
               
               
                 IL2RB 
                 interleukin 2 receptor, beta, mRNA [NM_000878] 
               
               
                 PTTG1 
                 pituitary tumor-transforming 1, mRNA [NM_004219] 
               
               
                 FANCI 
                 Fanconi anemia, complementation group I, mRNA  
               
               
                   
                 [NM_018193] 
               
               
                 PCSK6 
                 proprotein convertase subtilisin/kexin type 6, mRNA  
               
               
                   
                 [NM_138322, NM_002570] 
               
               
                 GZMH 
                 granzyme H (cathepsin G-like 2, protein h-CCPX),  
               
               
                   
                 mRNA [NM_033423] 
               
               
                 SLC11A1 
                 solute carrier family 11 (proton-coupled divalent metal  
               
               
                   
                 ion transporter), member 1, mRNA [NM_000578,  
               
               
                   
                 AK294707] 
               
               
                 ETS1 
                 v-ets avian erythroblastosis virus E26 oncogene  
               
               
                   
                 homolog 1, mRNA [NM_005238] 
               
               
                 CKAP5 
                 cytoskeleton associated protein 5, mRNA  
               
               
                   
                 [NM_001008938] 
               
               
                 WDFY3 
                 WD repeat and FYVE domain containing 3, mRNA  
               
               
                   
                 [NM_014991, AK092019] 
               
               
                 IL18R1 
                 interleukin 18 receptor 1, mRNA [NM_003855] 
               
               
                 HAVCR2 
                 hepatitis A virus cellular receptor 2, mRNA  
               
               
                   
                 [NM_032782] 
               
               
                 SH3BGRL2 
                 SH3 domain binding glutamic acid-rich protein like 2,  
               
               
                   
                 mRNA [NM_031469] 
               
               
                 CENPN 
                 centromere protein N, mRNA [NM_001100625,  
               
               
                   
                 NM_018455, NM_001100624] 
               
               
                 ATF2 
                 activating transcription factor 2, mRNA [NM_001880] 
               
               
                 EXOC1 
                 exocyst complex component 1, mRNA  
               
               
                   
                 [NM_001024924] 
               
               
                 KIR2DS3 
                 killer cell immunoglobulin-like receptor, two domains,  
               
               
                   
                 short cytoplasmic tail, 3, mRNA [NM_012313] 
               
               
                 TUBG1 
                 tubulin, gamma 1, mRNA [NM_001070] 
               
               
                 NUF2 
                 NUF2, NDC80 kinetochore complex component,  
               
               
                   
                 mRNA [NM_145697] 
               
               
                 SMC4 
                 structural maintenance of chromosomes 4, mRNA  
               
               
                   
                 [NM_005496] 
               
               
                 NUSAP1 
                 nucleolar and spindle associated protein 1, mRNA  
               
               
                   
                 [NM_016359] 
               
               
                 CHST15 
                 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O)  
               
               
                   
                 sulfotransferase 15, mRNA [NM_001270765,  
               
               
                   
                 NM_015892] 
               
               
                 PTPN4 
                 protein tyrosine phosphatase, non-receptor type 4  
               
               
                   
                 (megakaryocyte), mRNA [NM_002830] 
               
               
                 TACC3 
                 transforming, acidic coiled-coil containing protein 3,  
               
               
                   
                 mRNA [NM_006342] 
               
               
                 FGD4 
                 FYVE, RhoGEF and PH domain containing 4, mRNA  
               
               
                   
                 [NM_139241, AL713762] 
               
               
                 PLXND1 
                 plexin D1, mRNA [NM_015103] 
               
               
                 FCGR2A 
                 Fc fragment of IgG, low affinity IIa, receptor (CD32),  
               
               
                   
                 mRNA [NM_021642] 
               
               
                 CCR7 
                 chemokine (C-C motif) receptor 7, mRNA  
               
               
                   
                 [NM_001838] 
               
               
                 FANCD2 
                 Fanconi anemia, complementation group D2, mRNA  
               
               
                   
                 [NM_001018115, NM_033084] 
               
               
                 S1PR5 
                 sphingosine-1-phosphate receptor 5, mRNA  
               
               
                   
                 [NM_030760] 
               
               
                 HMBS 
                 hydroxymethylbilane synthase, mRNA [NM_000190] 
               
               
                 UBE2S 
                 ubiquitin-conjugating enzyme E2S, mRNA  
               
               
                   
                 [NM_014501] 
               
               
                 CD247 
                 CD247 molecule, mRNA [NM_198053, AK128376] 
               
               
                 FOXM1 
                 forkhead box M1, mRNA [NM_202002] 
               
               
                 NUP155 
                 nucleoporin 155 kDa, mRNA [NM_153485] 
               
               
                 CD7 
                 CD7 molecule, mRNA [NM_006137] 
               
               
                 RAB32 
                 RAB32, member RAS oncogene family, mRNA  
               
               
                   
                 [NM_006834] 
               
               
                 PLEKHF1 
                 pleckstrin homology domain containing, family F (with  
               
               
                   
                 FYVE domain) member 1, mRNA [NM_024310] 
               
               
                 EXO1 
                 exonuclease 1, mRNA [NM_003686] 
               
               
                 NNMT 
                 nicotinamide N-methyltransferase, mRNA  
               
               
                   
                 [NM_006169] 
               
               
                 CTSW 
                 cathepsin W, mRNA [NM_001335] 
               
               
                 TNFSF13 
                 tumor necrosis factor (ligand) superfamily, member 13,  
               
               
                   
                 mRNA [NM_172088] 
               
               
                 SKA1 
                 spindle and kinetochore associated complex subunit 1,  
               
               
                   
                 mRNA [NM_001039535] 
               
               
                 TXK 
                 TXK tyrosine kinase, mRNA [NM_003328] 
               
               
                 CDCA2 
                 cell division cycle associated 2, mRNA [NM_152562] 
               
               
                 DHFR 
                 dihydrofolate reductase, mRNA [NM_000791] 
               
               
                 MCM4 
                 minichromosome maintenance complex component 4,  
               
               
                   
                 mRNA [NM_005914] 
               
               
                 NPL 
                 N-acetylneuraminate pyruvate lyase  
               
               
                   
                 (dihydrodipicolinate synthase), mRNA  
               
               
                   
                 [BC034966, NM_001200056, NM_001200050] 
               
               
                 PRC1 
                 protein regulator of cytokinesis 1, mRNA  
               
               
                   
                 [NM_003981] 
               
               
                 ATIC 
                 5-aminoimidazole-4-carboxamide ribonucleotide  
               
               
                   
                 formyltransferase/IMP cyclohydrolase, mRNA  
               
               
                   
                 [NM_004044] 
               
               
                 AFF2 
                 AF4/FMR2 family, member 2, mRNA [X95463,  
               
               
                   
                 NM_002025] 
               
               
                 SLA2 
                 Src-like-adaptor 2, mRNA [NM_032214] 
               
               
                 SH2D2A 
                 SH2 domain containing 2A, mRNA [NM_003975,  
               
               
                   
                 NM_001161444] 
               
               
                 NCAPD3 
                 non-SMC condensin II complex, subunit D3, mRNA  
               
               
                   
                 [NM_015261] 
               
               
                 GPR114 
                 G protein-coupled receptor 114, mRNA  
               
               
                   
                 [XM_006721169] 
               
               
                 DPP4 
                 dipeptidyl-peptidase 4, mRNA [NM_001935] 
               
               
                 LAT 
                 linker for activation of T cells, mRNA [NM_014387] 
               
               
                 CLINT1 
                 clathrin interactor 1, mRNA [NM_014666] 
               
               
                 SPOCK2 
                 sparc/osteonectin, cwcv and kazal-like domains  
               
               
                   
                 proteoglycan (testican) 2, mRNA [NM_014767,  
               
               
                   
                 NM_001134434] 
               
               
                 TIGIT 
                 T cell immunoreceptor with Ig and ITIM domains,  
               
               
                   
                 mRNA [NM_173799] 
               
               
                 CXCR3 
                 chemokine (C-X-C motif) receptor 3, mRNA  
               
               
                   
                 [NM_001504, NM_001142797] 
               
               
                 CYBRD1 
                 cytochrome b reductase 1, mRNA [NM_024843] 
               
               
                 TMEM71 
                 transmembrane protein 71, mRNA [NM_144649] 
               
               
                 MCM5 
                 minichromosome maintenance complex component 5,  
               
               
                   
                 mRNA [NM_006739] 
               
               
                 TCHP 
                 trichoplein, keratin filament binding, mRNA  
               
               
                   
                 [NM_032300] 
               
               
                 SIRT1 
                 sirtuin 1, mRNA [NM_012238] 
               
               
                 ECM2 
                 extracellular matrix protein 2, female organ and  
               
               
                   
                 adipocyte specific, mRNA [NM_001393,  
               
               
                   
                 NM_001197296, BC036806] 
               
               
                 NACC2 
                 NACC family member 2, BEN and BTB (POZ) domain  
               
               
                   
                 containing, mRNA [NM_144653] 
               
               
                 CD5 
                 CD5 molecule, mRNA [NM_014207] 
               
               
                 PBX1 
                 pre-B-cell leukemia homeobox 1, mRNA  
               
               
                   
                 [NM_002585, AK093508] 
               
               
                 MPEG1 
                 macrophage expressed 1, mRNA [NM_001039396] 
               
               
                 STMN1 
                 stathmin 1, mRNA [NM_203401, NM_001145454] 
               
               
                 SLAMF7 
                 SLAM family member 7, mRNA [NM_021181] 
               
               
                 CLEC4E 
                 C-type lectin domain family 4, member E, mRNA  
               
               
                   
                 [NM_014358] 
               
               
                 ITGAX 
                 integrin, alpha X (complement component 3 receptor 4  
               
               
                   
                 subunit), mRNA [AK309642, NM_000887] 
               
               
                 UBASH3A 
                 ubiquitin associated and SH3 domain containing A,  
               
               
                   
                 mRNA [NM_018961, NM_001243467] 
               
               
                 TTC7B 
                 tetratricopeptide repeat domain 7B, mRNA  
               
               
                   
                 [NM_001010854] 
               
               
                 SPAG5 
                 sperm associated antigen 5, mRNA [NM_006461] 
               
               
                 IL21R 
                 interleukin 21 receptor, mRNA [NM_181078] 
               
               
                 GNLY 
                 granulysin, mRNA [NM_006433, AK310057] 
               
               
                 PRKCQ 
                 protein kinase C, theta, mRNA [NM_006257] 
               
               
                 KIF23 
                 kinesin family member 23, mRNA [NM_138555] 
               
               
                 NDUFA3 
                 NADH dehydrogenase (ubiquinone) 1 alpha  
               
               
                   
                 subcomplex, 3, 9 kDa, mRNA [NM_004542] 
               
               
                 F13A1 
                 coagulation factor XIII, A1 polypeptide, mRNA  
               
               
                   
                 [NM_000129] 
               
               
                 SAMD3 
                 sterile alpha motif domain containing 3, mRNA  
               
               
                   
                 [NM_001258275, NM_001017373] 
               
               
                 IKZF1 
                 IKAROS family zinc finger 1 (Ikaros), mRNA  
               
               
                   
                 [AF116605, NM_006060] 
               
               
                 RARRES3 
                 retinoic acid receptor responder (tazarotene induced) 3,  
               
               
                   
                 mRNA [NM_004585] 
               
               
                 GZMB 
                 granzyme B (granzyme 2, cytotoxic T-lymphocyte- 
               
               
                   
                 associated serine esterase 1), mRNA [NM_004131] 
               
               
                 EZH2 
                 enhancer of zeste homolog 2 ( Drosophila ), mRNA  
               
               
                   
                 [NM_004456] 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 7 
               
               
                   
               
               
                 marker genes for cancer, in particular prostate cancer 
               
               
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
            
               
                 COX7B 
                 MND1 
                 NOC3L 
                 RHOU 
                 ARFIP1 
               
               
                 LY96 
                 S100A12 
                 DEK 
                 PHTF2 
                 COX6C 
               
               
                 FIGNL1 
                 AGL 
                 HNMT 
                 S100A9 
                 DMD 
               
               
                 FOSL1 
                 NUPL2 
                 MS4A4A 
                 FAM198B 
                 KYNU 
               
               
                 S100A8 
                 PKMYT1 
                 TMEM55A 
                 ST3GAL6 
                 PIK3C2A 
               
               
                 GFRA3 
                 PTAFR 
                 TMX1 
                 CLK4 
                 NDUFB1 
               
               
                 REEP1 
                 VSTM1 
                 USP1 
                 CLEC12A 
                 VNN1 
               
               
                 SUV39H2 
                 SAMHD1 
                 CCDC80 
                 GCA 
                 MBNL1 
               
               
                 ZFYVE16 
                 ASPA 
                 PCNP 
                 VNN2 
                 ABCA1 
               
               
                 NDUFA4 
                 PPP1R12A 
                 SHCBP1 
                 C1GALT1C1 
                 PID1 
               
               
                 FOXN1 
                 UQCRQ 
                 PANK3 
                 DUSP6 
                 SRP9 
               
               
                 KIR2DL4 
                 OSMR 
                 PAQR3 
                 TNFAIP8 
                 MAD2L1 
               
               
                 GOLT1B 
                 SP3 
                 RNF138 
                 TLR4 
                 GLIPR1 
               
               
                 NLRC3 
                 JPH2 
                 CD302 
                 FBLN1 
                 NUP107 
               
               
                 ACTR6 
                 APCDD1 
                 NUP35 
                 LRRK2 
                 GZMK 
               
               
                 PLEKHF2 
                 ABCG2 
                 IMPA1 
                 SLC46A2 
                 STAG2 
               
               
                 TFEC 
                 TLR7 
                 MS4A7 
                 KIAA1468 
                 NDUFB3 
               
               
                 LGALS2 
                 ATP5C1 
                 SGMS1 
                 AIF1 
                 CYP1B1 
               
               
                 MSH6 
                 GINS1 
                 GALNT7 
                 HK3 
                 MYBL2 
               
               
                 TARP 
                 CKS2 
                 CA14 
                 SFRP4 
                 KLF1 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 8 
               
               
                   
               
               
                 marker genes for cancer, in particular prostate cancer 
               
               
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
            
               
                 COX7B 
                 FOXN1 
                 MND1 
                 UQCRQ 
                 NOC3L 
               
               
                 LY96 
                 KIR2DL4 
                 S100A12 
                 OSMR 
                 DEK 
               
               
                 FIGNL1 
                 GOLT1B 
                 AGL 
                 SP3 
                 HNMT 
               
               
                 FOSL1 
                 NLRC3 
                 NUPL2 
                 JPH2 
                 MS4A4A 
               
               
                 S100A8 
                 ACTR6 
                 PKMYT1 
                 APCDD1 
                 TMEM55A 
               
               
                 GFRA3 
                 PLEKHF2 
                 PTAFR 
                 ABCG2 
                 TMX1 
               
               
                 REEP1 
                 TFEC 
                 VSTM1 
                 TLR7 
                 USP1 
               
               
                 SUV39H2 
                 LGALS2 
                 SAMHD1 
                 ATP5C1 
                 CCDC80 
               
               
                 ZFYVE16 
                 MSH6 
                 ASPA 
                 GINS1 
                 PCNP 
               
               
                 NDUFA4 
                 TARP 
                 PPP1R12A 
                 CKS2 
                 SHCBP1 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 9 
               
               
                   
               
               
                 marker genes for cancer, in particular prostate cancer 
               
               
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
               
            
               
                 COX7B 
                 GFRA3 
                 FOXN1 
                 PLEKHF2 
                 MND1 
                 PTAFR 
               
               
                 LY96 
                 REEP1 
                 KIR2DL4 
                 TFEC 
                 S100A12 
                 VSTM1 
               
               
                 FIGNL1 
                 SUV39H2 
                 GOLT1B 
                 LGALS2 
                 AGL 
                 SAMHD1 
               
               
                 FOSL1 
                 ZFYVE16 
                 NLRC3 
                 MSH6 
                 NUPL2 
                 ASPA 
               
               
                 S100A8 
                 NDUFA4 
                 ACTR6 
                 TARP 
                 PKMYT1 
                 PPP1R12A 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 10 
               
               
                   
               
               
                 marker genes for cancer, in particular prostate cancer 
               
               
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
               
            
               
                   
                 COX7B 
                 FIGNL1 
                 S100A8 
                 REEP1 
                 ZFYVE16 
               
               
                   
                 LY96 
                 FOSL1 
                 GFRA3 
                 SUV39H2 
                 NDUFA4 
               
               
                   
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 11 
               
               
                   
               
               
                 marker genes that occur in both the PCA and NSCLC cluster 
               
               
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
               
            
               
                 LY96 
                 LMO2 
                 IRAK3 
                 SIRPA 
                 FCGRT 
                 GZMM 
               
               
                 FIGNL1 
                 KIAA0101 
                 ASGR2 
                 TRAT1 
                 CD8B 
                 IL7R 
               
               
                 S100A8 
                 RFC5 
                 CD36 
                 RASSF4 
                 PRF1 
                 MCM6 
               
               
                 NLRC3 
                 FEN1 
                 CD33 
                 PECAM1 
                 NCAM1 
                 CD1D 
               
               
                 TFEC 
                 PTPN22 
                 PSAP 
                 BUB1 
                 CYBB 
                 ASPM 
               
               
                 LGALS2 
                 CDKN3 
                 BCL6 
                 PYCARD 
                 SYK 
                 IL2RB 
               
               
                 MSH6 
                 QPCT 
                 LILRA6 
                 ARHGEF10L 
                 TBXAS1 
                 PTTG1 
               
               
                 TARP 
                 NDC80 
                 ACSL1 
                 ITM2A 
                 ZAP70 
                 FANCI 
               
               
                 MND1 
                 KIR2DS2 
                 SULF2 
                 LILRB1 
                 HJURP 
                 GZMH 
               
               
                 S100A12 
                 FPR1 
                 CRTAM 
                 GIMAP6 
                 PRKCD 
                 SLC11A1 
               
               
                 PKMYT1 
                 ENPP5 
                 GZMA 
                 RASGRP1 
                 KIF11 
                 ETS1 
               
               
                 PTAFR 
                 DPYD 
                 PGD 
                 AGPAT9 
                 RHOH 
                 CKAP5 
               
               
                 VSTM1 
                 TGFBI 
                 RFC4 
                 FPR2 
                 GRN 
                 WDFY3 
               
               
                 SAMHD1 
                 CDT1 
                 POLD3 
                 AURKB 
                 ITGAM 
                 IL18R1 
               
               
                 APCDD1 
                 KLRB1 
                 MYD88 
                 IMPA2 
                 XCL1 
                 CENPN 
               
               
                 TLR7 
                 SMC2 
                 SH2D1A 
                 CSF3R 
                 BTK 
                 KIR2DS3 
               
               
                 HNMT 
                 TYROBP 
                 NCF1 
                 PVRIG 
                 KIR2DS4 
                 TUBG1 
               
               
                 MS4A4A 
                 GMNN 
                 CD27 
                 RAD54L 
                 GINS2 
                 NUF2 
               
               
                 TMEM55A 
                 FGR 
                 HPSE 
                 ATP9A 
                 IL12RB2 
                 SMC4 
               
               
                 SHCBP1 
                 KIF18A 
                 UBE2T 
                 HOMER3 
                 FXYD6 
                 NUSAP1 
               
               
                 CD302 
                 KIF20B 
                 LILRA2 
                 TNS3 
                 NKG7 
                 CHST15 
               
               
                 RHOU 
                 RAD21 
                 LEF1 
                 NLRP12 
                 TBX21 
                 PTPN4 
               
               
                 S100A9 
                 SLC31A2 
                 KNTC1 
                 ADRB2 
                 EOMES 
                 FGD4 
               
               
                 FAM198B 
                 VNN3 
                 ACPP 
                 TLR2 
                 CPPED1 
                 FCGR2A 
               
               
                 ST3GAL6 
                 MARCO 
                 SLC7A7 
                 SERPINA1 
                 CST7 
                 CCR7 
               
               
                 CLEC12A 
                 KIF20A 
                 FGFBP2 
                 SLC24A4 
                 KIR2DL2 
                 S1PR5 
               
               
                 GCA 
                 RAB31 
                 TMPO 
                 GLT1D1 
                 STEAP4 
                 CD247 
               
               
                 VNN2 
                 TMEM154 
                 CEP76 
                 KLRK1 
                 RORA 
                 CD7 
               
               
                 DUSP6 
                 TLR1 
                 CPVL 
                 CX3CR1 
                 TCF7 
                 RAB32 
               
               
                 TLR4 
                 CD14 
                 TYMS 
                 BCL2 
                 MCTP1 
                 PLEKHF1 
               
               
                 LRRK2 
                 SPC25 
                 CDC25A 
                 MBOAT7 
                 CCNB2 
                 EXO1 
               
               
                 SLC46A2 
                 ASGR1 
                 CKS1B 
                 KIR2DL5A 
                 CCL5 
                 CTSW 
               
               
                 AIF1 
                 EVI5 
                 GPR171 
                 MELK 
                 TRIP13 
                 TNFSF13 
               
               
                 HK3 
                 TLR6 
                 POLA2 
                 PLXNB2 
                 PDGFRB 
                 TXK 
               
               
                 VNN1 
                 EMILIN2 
                 RAN 
                 KLRF1 
                 KLRC1 
                 CDCA2 
               
               
                 PID1 
                 CCNB1 
                 F5 
                 ANLN 
                 SCPEP1 
                 DHFR 
               
               
                 MAD2L1 
                 RNASE2 
                 CD2 
                 DOK3 
                 SP140 
                 MCM4 
               
               
                 GZMK 
                 CTSH 
                 NDUFA8 
                 PRKCH 
                 POLA1 
                 NPL 
               
               
                 CYP1B1 
                 S1PR3 
                 RBM47 
                 ABLIM1 
                 FASLG 
                 SLA2 
               
               
                 MYBL2 
                 IL1RN 
                 CST3 
                 EMR2 
                 SORT1 
                 SH2D2A 
               
               
                 IFI30 
                 CEP55 
                 SKA3 
                 P2RY13 
                 DTYMK 
                 NCAPD3 
               
               
                 ICOS 
                 ECT2 
                 SLAMF1 
                 KIR3DL1 
                 SMARCAL1 
                 GPR114 
               
               
                 CD28 
                 AQP9 
                 NUP88 
                 CD163 
                 ITK 
                 DPP4 
               
               
                 SGK1 
                 FES 
                 BRCA1 
                 CDCA7 
                 NFAM1 
                 LAT 
               
               
                 PLA2G7 
                 RNF130 
                 CYFIP1 
                 HHEX 
                 ITPR3 
                 SPOCK2 
               
               
                 RMI1 
                 PADI2 
                 TIPIN 
                 KLRC3 
                 E2F7 
                 TIGIT 
               
               
                 CCR2 
                 TPX2 
                 LILRB2 
                 GINS4 
                 SIGLEC7 
                 CXCR3 
               
               
                 FCN1 
                 NEK2 
                 IL13RA1 
                 PRAM1 
                 PCNA 
                 CYBRD1 
               
               
                 ZWINT 
                 CSF1R 
                 NCF4 
                 IFNGR2 
                 ANO10 
                 MCM5 
               
               
                 AMICA1 
                 RPA3 
                 LTBR 
                 SPI1 
                 SSBP1 
                 TCHP 
               
               
                 CLEC7A 
                 SMARCD3 
                 ALOX5 
                 MEGF9 
                 TGFBR3 
                 NACC2 
               
               
                 MSH2 
                 GPR56 
                 CRISPLD2 
                 CDCA8 
                 CENPE 
                 CD5 
               
               
                 MFSD1 
                 MGST1 
                 PYGL 
                 ALDH2 
                 CARD9 
                 MPEG1 
               
               
                 KCNJ2 
                 FCGR1B 
                 CFP 
                 RNASE6 
                 CHAF1B 
                 STMN1 
               
               
                 IFNG 
                 KCNE3 
                 KIF2C 
                 STAT4 
                 CD8A 
                 SLAMF7 
               
               
                 CSTA 
                 MS4A6A 
                 HCK 
                 SLC15A3 
                 CDCA5 
                 CLEC4E 
               
               
                 MYBL1 
                 SIRPB1 
                 THEMIS 
                 PLK1 
                 CEP72 
                 UBASH3A 
               
               
                 MNDA 
                 RAD51 
                 KIAA1598 
                 CDK1 
                 HOPX 
                 SPAG5 
               
               
                 RBP7 
                 PLBD1 
                 TIMP2 
                 FBP1 
                 TLR8 
                 IL21R 
               
               
                 BST1 
                 LAT2 
                 GATA3 
                 CLIC3 
                 SLC16A3 
                 GNLY 
               
               
                 DLGAP5 
                 LILRB3 
                 NLRP3 
                 MYO1F 
                 CD96 
                 PRKCQ 
               
               
                 NOD2 
                 LILRA5 
                 UHRF1 
                 S100A11 
                 CAMK4 
                 KIF23 
               
               
                 LILRA3 
                 PRIM1 
                 OIP5 
                 AOAH 
                 CENPF 
                 F13A1 
               
               
                 CLEC4A 
                 CFD 
                 PAK1 
                 CD3D 
                 LCK 
                 SAMD3 
               
               
                 TNFSF13B 
                 NCF2 
                 LY86 
                 TMTC2 
                 KCTD12 
                 IKZF1 
               
               
                 CSF2RA 
                 AGTRAP 
                 KLRD1 
                 PTGDR 
                 CASC5 
                 RARRES3 
               
               
                 BRI3 
                 GIMAP7 
                 DTL 
                 TREM1 
                 SGOL2 
                 GZMB 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 12 
               
               
                   
               
               
                 selected marker genes that occur in both the PCA and NSCLC cluster 
               
               
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
            
               
                 LY96 
                 CD302 
                 IFI30 
                 DLGAP5 
                 CDT1 
               
               
                 FIGNL1 
                 RHOU 
                 ICOS 
                 NOD2 
                 KLRB1 
               
               
                 S100A8 
                 S100A9 
                 CD28 
                 LILRA3 
                 SMC2 
               
               
                 NLRC3 
                 FAM198B 
                 SGK1 
                 CLEC4A 
                 TYROBP 
               
               
                 TFEC 
                 ST3GAL6 
                 PLA2G7 
                 TNFSF13B 
                 GMNN 
               
               
                 LGALS2 
                 CLEC12A 
                 RMI1 
                 CSF2RA 
                 FGR 
               
               
                 MSH6 
                 GCA 
                 CCR2 
                 BRI3 
                 KIF18A 
               
               
                 TARP 
                 VNN2 
                 FCN1 
                 LMO2 
                 KIF20B 
               
               
                 MND1 
                 DUSP6 
                 ZWINT 
                 KIAA0101 
                 RAD21 
               
               
                 S100A12 
                 TLR4 
                 AMICA1 
                 RFC5 
                 SLC31A2 
               
               
                 PKMYT1 
                 LRRK2 
                 CLEC7A 
                 FEN1 
                 VNN3 
               
               
                 PTAFR 
                 SLC46A2 
                 MSH2 
                 PTPN22 
                 MARCO 
               
               
                 VSTM1 
                 AIF1 
                 MFSD1 
                 CDKN3 
                 KIF20A 
               
               
                 SAMHD1 
                 HK3 
                 KCNJ2 
                 QPCT 
                 RAB31 
               
               
                 APCDD1 
                 VNN1 
                 IFNG 
                 NDC80 
                 TMEM154 
               
               
                 TLR7 
                 PID1 
                 CSTA 
                 KIR2DS2 
                 TLR1 
               
               
                 HNMT 
                 MAD2L1 
                 MYBL1 
                 FPR1 
                 CD14 
               
               
                 MS4A4A 
                 GZMK 
                 MNDA 
                 ENPP5 
                 SPC25 
               
               
                 TMEM55A 
                 CYP1B1 
                 RBP7 
                 DPYD 
                 ASGR1 
               
               
                 SHCBP1 
                 MYBL2 
                 BST1 
                 TGFBI 
                 EVI5 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 13 
               
               
                   
               
               
                 selected marker genes that occur in both the PCA and NSCLC cluster 
               
               
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
            
               
                 LY96 
                 PKMYT1 
                 CD302 
                 LRRK2 
                 IFI30 
               
               
                 FIGNL1 
                 PTAFR 
                 RHOU 
                 SLC46A2 
                 ICOS 
               
               
                 S100A8 
                 VSTM1 
                 S100A9 
                 AIF1 
                 CD28 
               
               
                 NLRC3 
                 SAMHD1 
                 FAM198B 
                 HK3 
                 SGK1 
               
               
                 TFEC 
                 APCDD1 
                 ST3GAL6 
                 VNN1 
                 PLA2G7 
               
               
                 LGALS2 
                 TLR7 
                 CLEC12A 
                 PID1 
                 RMI1 
               
               
                 MSH6 
                 HNMT 
                 GCA 
                 MAD2L1 
                 CCR2 
               
               
                 TARP 
                 MS4A4A 
                 VNN2 
                 GZMK 
                 FCN1 
               
               
                 MND1 
                 TMEM55A 
                 DUSP6 
                 CYP1B1 
                 ZWINT 
               
               
                 S100A12 
                 SHCBP1 
                 TLR4 
                 MYBL2 
                 AMICA1 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 14 
               
               
                   
               
               
                 selected marker genes that occur in both the PCA and NSCLC cluster 
               
               
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
               
            
               
                 LY96 
                 LGALS2 
                 PKMYT1 
                 TLR7 
                 CD302 
                 CLEC12A 
               
               
                 FIGNL1 
                 MSH6 
                 PTAFR 
                 HNMT 
                 RHOU 
                 GCA 
               
               
                 S100A8 
                 TARP 
                 VSTM1 
                 MS4A4A 
                 S100A9 
                 VNN2 
               
               
                 NLRC3 
                 MND1 
                 SAMHD1 
                 TMEM55A 
                 FAM198B 
                 DUSP6 
               
               
                 TFEC 
                 S100A12 
                 APCDD1 
                 SHCBP1 
                 ST3GAL6 
                 TLR4 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 15 
               
               
                   
               
               
                 selected marker genes that occur in both the PCA and NSCLC cluster 
               
               
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
            
               
                 LY96 
                 S100A8 
                 TFEC 
                 MSH6 
                 MND1 
               
               
                 FIGNL1 
                 NLRC3 
                 LGALS2 
                 TARP 
                 S100A12 
               
               
                   
               
            
           
         
       
     
     EXAMPLES 
     Study 1 
     The Examples shown in the following are merely illustrative and shall describe the present invention in a further way. These Examples shall not be construed to limit the present invention thereto. 
     CV9201 as described in WO2009046974 and Sebastian et al. BMC Cancer 2014, 14:748) is an mRNA-based cancer immunotherapeutic agent/vaccine comprising following cancer antigens: MAGE-C1, MAGE-C2, NY-ESO-1, Survivin and 5T4. Repeated vaccinations of NSCLC patients with 320 μg RNA for each antigen (1.600 μg RNA in total) were carried out at weeks 1, 2, 3, 5, and 7. Peripheral blood samples were taken at weeks 0 (baseline), 5 and 9 (2 weeks post 3rd treatment and 2 weeks post 5th treatment, respectively). 
     Peripheral blood mono-nuclear cells (PBMCs) were isolated by Ficoll density centrifugation. Briefly, around 20 ml of blood were pipetted layered onto a LeucoSep tube (greiner bio-one) and centrifuged for 20 minutes without brake. PBMCs from the interphase were washed three times in PBS and suspended in cryo SFM (PromoCell) and cryopreserved in liquid nitrogen. Cells were thawed for immune analyses and 1 million left-over PBMCs were suspended in PBS and frozen. 
     RNA was isolated from re-thawed PBMCs using RNEasy (Qiagen) according to the manufacturer&#39;s instructions. RNA quality control was performed on a 2100 Bioanalyzer (Agilent Technologies) and a RIN threshold of 6.5 was used as cutoff. Cyanine-3-labelling of cRNA and hybridization using the Agilent SurePrint G3 Human Gene Expression 8×60K v2 Microarray platform was performed by IMGM according to manufacturer&#39;s manuals (Agilent Technologies). Raw data was processed using following software tools: Feature Extraction 10.7.3.1 and GeneSpring GX 12.6.1. Quantile normalization was performed and log 2-transformed and filtered for probes detectable in at least one sample. 
     Altogether 22 stage IV non-small cell lung cancer patients were evaluable in the transcriptional profiling study and gene expression data was obtained for 48,605 probes. To reduce the data set, we made use of blood transcriptional modules (BTMs) developed by the Pulendran group [1]. These altogether 346 BTMs represent sets of genes, which are transcriptionally co-regulated. Most of these BTMs reflect an immunological process, such as signaling pathways or represent sets of genes specifically enriched in immune cells, such as T or B cells. We first calculated the BTM activity scores, which represent the mean expression of all genes contained in a module. Probes with the highest average expression across all samples were chosen for genes targeted by multiple probes. 
     To monitor changes between baseline and post vaccine time points, BTM activity score differences between week 0 (pre-treatment time point) and week 5 (2 weeks post 3rd treatment) were calculated (Table 6). More specifically, gene expression differences between week 5 and week 0 were calculated for each patient in cluster 1. Subsequently, the mean of the week 5 to 0 differences was determined for all patients in cluster 1 (Week5_0 GE difference_mean_pat_clust1). Analogously, gene expression differences between week 5 and week 0 were calculated for each patient in cluster 2. Subsequently, the mean of the week 5 to 0 differences was determined for all patients in cluster 2 (Week5_0 GE difference_mean_pat_clust2). Both values (“Week5_0 GE difference_mean_pat_clust1” and “Week5_0 GE difference_mean_pat_clust2”) thus signify the mean change in gene expression comparing post treatment week 5 with the baseline value week 0 within a given group of patients. The difference between “Week5_0 GE difference_mean_pat_clust1” and “Week5_0 GE difference_mean_pat_clust2” was calculated (difference). 
     Unsupervised hierarchical clustering of module activity scores identified three distinct clusters of BTM week 5 to week 0 changes: a T/NK cell cluster, a cell cycle cluster and a myeloid/immune activation cluster ( FIG. 1 ). Furthermore, unsupervised hierarchical clustering of samples identified three clusters of patients (patient cluster 1, 2a and 2b). Patients belonging to clusters 2a and 2b exhibited prolonged survival compared to patients from cluster 1 ( FIG. 2 ). 
     We next sought to determine the single genes either driving or being associated with the clustering of the BTMs. To this end, gene expression differences between week 5 and corresponding week 0 samples were calculated for the entire transcriptome. As described above, probes with highest average expression were chosen if genes were targeted by multiple probes. 
     To identify genes differentially expressed in patient cluster 1 compared to cluster 2, following approaches were utilized: patients were grouped according to aforementioned clusters Genes were ranked according to p values comparing patient clusters 1 and 2 (t test) or clusters 1 versus 2a and 2b (ANOVA). Thus, altogether four comparisons were performed. The first top 100 hits were picked from each comparison. In addition, gene set enrichment analysis was performed to identify the top 15 BTMs enriched at week 5 in the patient clusters 1, 2a and 2b. Leading edge genes for these top 15 BTMs were identified and all duplicate genes were removed. Thus, a final list was generated comprising 914 single genes (as shown in Table 1). By unsupervised hierarchical clustering of these single gene expression changes (914 genes) (week 5 to week 0 differences) the patients could be segregated into the two groups of short term survivors and moderate/longterm survivors. Unsupervised hierarchical clustering of BTM activity scores was performed using Euclidean distance and average linkage clustering. The 915 genes were ranked based on their ability to differentiate between patients derived from cluster 1 and patients derived from cluster 2. Top 100 (Table 2;  FIG. 3  A), top 50 (Table 3,  FIG. 3  B), or top 30 (Table 4;  FIG. 3  C) genes were selected, and gene expression differences between week 5 and 0 were calculated followed by average-linkage hierarchical clustering. Clustering trees of patients are shown and short-term survivors are highlighted. 
     
       
         
           
               
             
               
                 TABLE 16 
               
             
            
               
                   
               
               
                 Study 1 - gene expression differences between week 5 and  
               
               
                 week 0 of marker genes (full name and accession number as set  
               
               
                 out in Table 1) 
               
            
           
           
               
               
               
               
            
               
                   
                 Week5_0 GE  
                 Week5_0 GE  
                   
               
               
                   
                 difference_ 
                 difference_ 
                   
               
               
                   
                 mean_pat_ 
                 mean_pat_ 
                   
               
               
                 Gene Symbol 
                 clust1 
                 clust2 
                 Difference 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 LOC572558 
                 0.836493129 
                 −0.56501209 
                 1.40150522 
               
               
                 USH1G 
                 0.5566099 
                 −0.82634535 
                 1.38295525 
               
               
                 BMP2 
                 0.598134986 
                 −0.73352584 
                 1.33166082 
               
               
                 KIF18A 
                 −0.4757864 
                 0.79021046 
                 1.26599686 
               
               
                 ANLN 
                 −0.52647626 
                 0.72441581 
                 1.25089207 
               
               
                 GP5 
                 −0.68564021 
                 0.49620231 
                 1.18184253 
               
               
                 SKA3 
                 −0.3279785 
                 0.82917226 
                 1.15715076 
               
               
                 TTK 
                 −0.22210423 
                 0.89190909 
                 1.11401331 
               
               
                 OLFM4 
                 0.5396805 
                 −0.55518684 
                 1.09486734 
               
               
                 DLGAP5 
                 −0.43158276 
                 0.63624947 
                 1.06783223 
               
               
                 MCM10 
                 −0.27769329 
                 0.78038119 
                 1.05807447 
               
               
                 SLPI 
                 0.750556771 
                 −0.29516672 
                 1.04572349 
               
               
                 FASLG 
                 −0.40907543 
                 0.63064534 
                 1.03972076 
               
               
                 SLC7A8 
                 0.507136586 
                 −0.52383601 
                 1.03097259 
               
               
                 EXO1 
                 −0.4247823 
                 0.59886942 
                 1.02365172 
               
               
                 FGFBP2 
                 −0.52265307 
                 0.47477268 
                 0.99742575 
               
               
                 CXCL1 
                 0.356745571 
                 −0.64063769 
                 0.99738326 
               
               
                 MELK 
                 −0.45311947 
                 0.54402785 
                 0.99714732 
               
               
                 RRM2 
                 −0.32322949 
                 0.65163608 
                 0.97486556 
               
               
                 KIAA0101 
                 −0.47635057 
                 0.48525963 
                 0.9616102 
               
               
                 IF127 
                 0.176026157 
                 1.11120696 
                 0.9351808 
               
               
                 RAD51 
                 −0.3247114 
                 0.60031006 
                 0.92502146 
               
               
                 TYMS 
                 −0.437593 
                 0.48260443 
                 0.92019743 
               
               
                 E2F8 
                 0.040218886 
                 0.95494481 
                 0.91472592 
               
               
                 PDGFRB 
                 −0.39981491 
                 0.51231926 
                 0.91213417 
               
               
                 CHI3L1 
                 0.588718757 
                 −0.31388162 
                 0.90260038 
               
               
                 IFNG 
                 −0.42609171 
                 0.47086009 
                 0.8969518 
               
               
                 CDT1 
                 −0.39202781 
                 0.50043445 
                 0.89246226 
               
               
                 CCL20 
                 0.556402414 
                 −0.32817589 
                 0.88457831 
               
               
                 DTL 
                 −0.32041199 
                 0.56387945 
                 0.88429144 
               
               
                 LOC643650 
                 0.665895186 
                 −0.2064908 
                 0.87238599 
               
               
                 CCNA2 
                 −0.35663496 
                 0.51559274 
                 0.8722277 
               
               
                 RGS9 
                 −0.39346829 
                 0.47757099 
                 0.87103927 
               
               
                 CEP55 
                 −0.24708361 
                 0.61351535 
                 0.86059896 
               
               
                 POLE2 
                 −0.5204712 
                 0.33988834 
                 0.86035954 
               
               
                 ASPM 
                 −0.32645329 
                 0.53236356 
                 0.85881685 
               
               
                 TGFBR3 
                 −0.52647194 
                 0.3242523 
                 0.85072424 
               
               
                 RPGRIP1 
                 0.447854257 
                 −0.40147147 
                 0.84932573 
               
               
                 KIR2DL2 
                 −0.5014236 
                 0.33998994 
                 0.84141354 
               
               
                 HJURP 
                 −0.34120807 
                 0.49581671 
                 0.83702478 
               
               
                 STAP1 
                 −0.39942023 
                 0.43645486 
                 0.83587509 
               
               
                 TOP2A 
                 −0.4450913 
                 0.38674186 
                 0.83183316 
               
               
                 XLOC_l2_010897 
                 0.547097857 
                 −0.28466364 
                 0.8317615 
               
               
                 PPP2R2B 
                 −0.37462457 
                 0.45606007 
                 0.83068464 
               
               
                 SPC25 
                 −0.38262983 
                 0.44521026 
                 0.82784009 
               
               
                 KIAA1671 
                 −0.35329513 
                 0.47447439 
                 0.82776952 
               
               
                 BUB1 
                 −0.25203216 
                 0.5736033 
                 0.82563546 
               
               
                 GPR56 
                 −0.39415557 
                 0.42937814 
                 0.82353371 
               
               
                 GZMM 
                 −0.52771514 
                 0.29230996 
                 0.82002511 
               
               
                 SAMD3 
                 −0.372721 
                 0.44468854 
                 0.81740954 
               
               
                 CTSW 
                 −0.487019 
                 0.32969107 
                 0.81671007 
               
               
                 PTGFRN 
                 0.551742114 
                 −0.25487401 
                 0.80661612 
               
               
                 XLOC_006752 
                 0.348433857 
                 −0.45524939 
                 0.80368325 
               
               
                 GNLY 
                 −0.44419471 
                 0.35938757 
                 0.80358229 
               
               
                 LINC00239 
                 −0.41751591 
                 0.38543004 
                 0.80294595 
               
               
                 CDCA2 
                 −0.38017363 
                 0.42248241 
                 0.80265604 
               
               
                 GZMH 
                 −0.36358736 
                 0.43763271 
                 0.80122007 
               
               
                 BUB1B 
                 −0.3748953 
                 0.42602996 
                 0.80092526 
               
               
                 UBE2C 
                 −0.38013587 
                 0.41798133 
                 0.7981172 
               
               
                 KIR2DS4 
                 −0.46300439 
                 0.33428446 
                 0.79728885 
               
               
                 SLAMF6 
                 −0.3265845 
                 0.46976723 
                 0.79635173 
               
               
                 KIR2DS2 
                 −0.512763 
                 0.28105043 
                 0.79381343 
               
               
                 XLOC_004032 
                 0.388846443 
                 −0.40493636 
                 0.7937828 
               
               
                 PRF1 
                 −0.36652071 
                 0.42110561 
                 0.78762632 
               
               
                 GINS2 
                 −0.31950007 
                 0.46183131 
                 0.78133139 
               
               
                 CDC45 
                 −0.36169197 
                 0.41810126 
                 0.77979323 
               
               
                 TBX21 
                 −0.38747943 
                 0.3888075 
                 0.77628693 
               
               
                 GZMA 
                 −0.32334621 
                 0.44860282 
                 0.77194904 
               
               
                 NKG7 
                 −0.40032814 
                 0.36869686 
                 0.769025 
               
               
                 SGK1 
                 0.316197857 
                 −0.45204007 
                 0.76823793 
               
               
                 PVRIG 
                 −0.33004371 
                 0.43754479 
                 0.7675885 
               
               
                 NEK2 
                 −0.4797225 
                 0.28285472 
                 0.76257722 
               
               
                 TARP 
                 −0.32536107 
                 0.43529539 
                 0.76065646 
               
               
                 BIRC5 
                 −0.36301359 
                 0.39512951 
                 0.7581431 
               
               
                 CST7 
                 −0.40688907 
                 0.35034489 
                 0.75723396 
               
               
                 IL2RB 
                 −0.43837371 
                 0.31879714 
                 0.75717086 
               
               
                 MND1 
                 −0.239129 
                 0.51650061 
                 0.75562961 
               
               
                 S1PR5 
                 −0.4823231 
                 0.27190594 
                 0.75422904 
               
               
                 STK32B 
                 0.403095857 
                 −0.34853537 
                 0.75163123 
               
               
                 KLRF1 
                 −0.42285957 
                 0.32693082 
                 0.74979039 
               
               
                 ENPP5 
                 −0.19809159 
                 0.55005255 
                 0.74814414 
               
               
                 IL18RAP 
                 −0.43409771 
                 0.31250082 
                 0.74659854 
               
               
                 GRAP2 
                 −0.39740214 
                 0.34823431 
                 0.74563645 
               
               
                 SH2D2A 
                 −0.37704021 
                 0.36344946 
                 0.74048968 
               
               
                 CR1 
                 0.513004429 
                 −0.22538764 
                 0.73839207 
               
               
                 IQCD 
                 0.443972843 
                 −0.29392262 
                 0.73789546 
               
               
                 CCL5 
                 −0.37457179 
                 0.36271357 
                 0.73728536 
               
               
                 KLRD1 
                 −0.39966243 
                 0.33700039 
                 0.73666282 
               
               
                 CXCR3 
                 −0.33505586 
                 0.40025993 
                 0.73531579 
               
               
                 CD247 
                 −0.42550657 
                 0.30918132 
                 0.73468789 
               
               
                 ZNF697 
                 0.343343186 
                 −0.38604165 
                 0.72938484 
               
               
                 HOPX 
                 −0.40795114 
                 0.31981293 
                 0.72776407 
               
               
                 IL1B 
                 0.430601643 
                 −0.29520746 
                 0.72580911 
               
               
                 KLRC1 
                 −0.40147829 
                 0.32408429 
                 0.72556257 
               
               
                 ZNF503 
                 0.260294643 
                 −0.46513275 
                 0.72542739 
               
               
                 XLOC_004924 
                 0.442685629 
                 −0.28242409 
                 0.72510971 
               
               
                 ZAP70 
                 −0.37333843 
                 0.35043057 
                 0.723769 
               
               
                 CENPF 
                 −0.26337054 
                 0.45853571 
                 0.72190625 
               
               
                 PTPRCAP 
                 −0.32277993 
                 0.39478421 
                 0.71756414 
               
               
                 KLRC3 
                 −0.44044429 
                 0.27508348 
                 0.71552776 
               
               
                 OIP5 
                 −0.21582867 
                 0.49771236 
                 0.71354104 
               
               
                 PYHIN1 
                 −0.40307107 
                 0.31045202 
                 0.71352309 
               
               
                 KIR3DL1 
                 −0.45761089 
                 0.25522369 
                 0.71283457 
               
               
                 FFAR2 
                 0.403203914 
                 −0.3020409 
                 0.70524481 
               
               
                 DOCK4 
                 0.5071245 
                 −0.19795293 
                 0.70507743 
               
               
                 KIR2DL5A 
                 −0.36701536 
                 0.33725142 
                 0.70426678 
               
               
                 STAT4 
                 −0.36686936 
                 0.33649532 
                 0.70336468 
               
               
                 CCNB1 
                 −0.22058387 
                 0.48166149 
                 0.70224536 
               
               
                 NLRC3 
                 −0.32309807 
                 0.37479546 
                 0.69789354 
               
               
                 CD226 
                 −0.3092581 
                 0.38837247 
                 0.69763057 
               
               
                 LIN7A 
                 0.384615571 
                 −0.31028161 
                 0.69489718 
               
               
                 CCDC102A 
                 −0.25091279 
                 0.44355494 
                 0.69446773 
               
               
                 SBK1 
                 −0.32368543 
                 0.36739386 
                 0.69107929 
               
               
                 CD1D 
                 0.332267257 
                 −0.35830728 
                 0.69057454 
               
               
                 MCM2 
                 −0.26376014 
                 0.42386507 
                 0.68762521 
               
               
                 CDCA5 
                 −0.32649949 
                 0.35916156 
                 0.68566105 
               
               
                 CRISPLD2 
                 0.325558914 
                 −0.35866663 
                 0.68422554 
               
               
                 SPC24 
                 −0.20801669 
                 0.47344263 
                 0.68145931 
               
               
                 TXK 
                 −0.39899106 
                 0.28206181 
                 0.68105287 
               
               
                 MYBL1 
                 −0.32378307 
                 0.35550657 
                 0.67928964 
               
               
                 FLJ23867 
                 0.2892186 
                 −0.38841893 
                 0.67763753 
               
               
                 CAMP 
                 0.331554029 
                 −0.34489608 
                 0.67645011 
               
               
                 DLL1 
                 −0.40856636 
                 0.26751013 
                 0.67607649 
               
               
                 STMN1 
                 −0.32491957 
                 0.34691546 
                 0.67183504 
               
               
                 PTGDR 
                 −0.24607819 
                 0.42568543 
                 0.67176361 
               
               
                 CD7 
                 −0.44135829 
                 0.228816 
                 0.67017429 
               
               
                 XLOC_011068 
                 0.358870857 
                 −0.31087044 
                 0.6697413 
               
               
                 TREM1 
                 0.319241571 
                 −0.34985461 
                 0.66909618 
               
               
                 CLMN 
                 0.417658286 
                 −0.24783318 
                 0.66549146 
               
               
                 TIGIT 
                 −0.22869957 
                 0.43677026 
                 0.66546983 
               
               
                 CLIC3 
                 −0.46189586 
                 0.20322614 
                 0.665122 
               
               
                 IL32 
                 −0.28410986 
                 0.37717586 
                 0.66128571 
               
               
                 APCDD1 
                 0.5716404 
                 −0.08941537 
                 0.66105577 
               
               
                 ZFHX3 
                 0.258988 
                 −0.39967111 
                 0.65865911 
               
               
                 ST3GAL6 
                 0.454685 
                 −0.20187069 
                 0.65655569 
               
               
                 CXCR6 
                 −0.1687038 
                 0.48423314 
                 0.65293694 
               
               
                 EVI5 
                 0.304583 
                 −0.34727826 
                 0.65186126 
               
               
                 CDK1 
                 −0.29766186 
                 0.35394821 
                 0.65161007 
               
               
                 XLOC_002344 
                 0.278257714 
                 −0.37277171 
                 0.65102942 
               
               
                 GAS2L3 
                 0.2892733 
                 −0.36166317 
                 0.65093647 
               
               
                 BRIP1 
                 −0.06473094 
                 0.58398673 
                 0.64871767 
               
               
                 C15orf38 
                 0.352214186 
                 −0.29639379 
                 0.64860798 
               
               
                 ST6GALNAC2 
                 0.362440414 
                 −0.28541456 
                 0.64785498 
               
               
                 LOC100131043 
                 0.497533014 
                 −0.14947804 
                 0.64701106 
               
               
                 NLRP3 
                 0.198566786 
                 −0.44595868 
                 0.64452546 
               
               
                 TMEM144 
                 0.445366286 
                 −0.19525502 
                 0.64062131 
               
               
                 KLRK1 
                 −0.29429236 
                 0.34556071 
                 0.63985307 
               
               
                 ELOVL4 
                 0.575955571 
                 −0.06378644 
                 0.63974201 
               
               
                 XCL1 
                 −0.46850007 
                 0.17072114 
                 0.63922121 
               
               
                 NDFIP2 
                 −0.13406246 
                 0.50343696 
                 0.63749941 
               
               
                 AHR 
                 0.425404357 
                 −0.20952718 
                 0.63493154 
               
               
                 XLOC_001266 
                 0.341852057 
                 −0.29172474 
                 0.6335768 
               
               
                 SETD7 
                 0.278564214 
                 −0.35465161 
                 0.63321582 
               
               
                 GZMB 
                 −0.38500943 
                 0.24324889 
                 0.62825832 
               
               
                 F2RL1 
                 0.430577814 
                 −0.19752631 
                 0.62810412 
               
               
                 SLA2 
                 −0.37827891 
                 0.24943868 
                 0.62771759 
               
               
                 PTPN4 
                 −0.33267557 
                 0.29473275 
                 0.62740832 
               
               
                 CHAF1B 
                 −0.28010579 
                 0.34651381 
                 0.6266196 
               
               
                 CD3D 
                 −0.23348186 
                 0.39212054 
                 0.62560239 
               
               
                 PRKCH 
                 −0.35848186 
                 0.26582529 
                 0.62430714 
               
               
                 KIF20A 
                 −0.21280003 
                 0.41019729 
                 0.62299732 
               
               
                 KIFC1 
                 −0.10751596 
                 0.51517141 
                 0.62268736 
               
               
                 HP 
                 0.596373071 
                 −0.02630196 
                 0.62267504 
               
               
                 CDCA7 
                 −0.21515 
                 0.40727161 
                 0.62242161 
               
               
                 ITM2A 
                 −0.26605336 
                 0.35634646 
                 0.62239982 
               
               
                 XLOC_011350 
                 0.295312529 
                 −0.32692951 
                 0.62224204 
               
               
                 IL8 
                 0.216571714 
                 −0.40485764 
                 0.62142936 
               
               
                 LOC79015 
                 −0.27151643 
                 0.34920865 
                 0.62072508 
               
               
                 UBE2T 
                 −0.11525863 
                 0.50473483 
                 0.61999346 
               
               
                 PLEKHF1 
                 −0.27916886 
                 0.33819318 
                 0.61736204 
               
               
                 KLRB1 
                 −0.38298343 
                 0.23405564 
                 0.61703907 
               
               
                 PLB1 
                 0.396175286 
                 −0.22081686 
                 0.61699214 
               
               
                 CD3G 
                 −0.28115043 
                 0.33538586 
                 0.61653629 
               
               
                 NDC80 
                 −0.26965786 
                 0.34558996 
                 0.61524782 
               
               
                 ELOVL6 
                 −0.2569174 
                 0.3583198 
                 0.6152372 
               
               
                 CDKN3 
                 −0.23962386 
                 0.37401346 
                 0.61363731 
               
               
                 CENPA 
                 −0.28117887 
                 0.3316836 
                 0.61286247 
               
               
                 RNF217 
                 0.367217271 
                 −0.24210219 
                 0.60931946 
               
               
                 ORM1 
                 0.327330243 
                 −0.28103712 
                 0.60836736 
               
               
                 ATP6V0A1 
                 0.410282 
                 −0.19580129 
                 0.60608329 
               
               
                 ASGR2 
                 0.394543714 
                 −0.20919582 
                 0.60373954 
               
               
                 ZWINT 
                 −0.22816706 
                 0.37430662 
                 0.60247368 
               
               
                 LRP1 
                 0.342941071 
                 −0.25913879 
                 0.60207986 
               
               
                 CD6 
                 −0.23678907 
                 0.36355446 
                 0.60034354 
               
               
                 GPR114 
                 −0.29362574 
                 0.30667602 
                 0.60030176 
               
               
                 AQP9 
                 0.451633286 
                 −0.14842921 
                 0.6000625 
               
               
                 CD3E 
                 −0.351057 
                 0.24763504 
                 0.59869204 
               
               
                 RASGRP1 
                 −0.29033786 
                 0.30770064 
                 0.5980385 
               
               
                 CD2 
                 −0.21646543 
                 0.38027496 
                 0.59674039 
               
               
                 MCM4 
                 −0.23200734 
                 0.36402665 
                 0.59603399 
               
               
                 FAM20C 
                 0.354564429 
                 −0.24098214 
                 0.59554657 
               
               
                 IL13RA1 
                 0.222207429 
                 −0.37244486 
                 0.59465229 
               
               
                 CCNB2 
                 −0.19466363 
                 0.39873935 
                 0.59340298 
               
               
                 XLOC_l2_015034 
                 0.194223386 
                 −0.39885572 
                 0.59307911 
               
               
                 PRKCQ 
                 −0.30476429 
                 0.28771886 
                 0.59248314 
               
               
                 CLEC4E 
                 0.2837066 
                 −0.30689578 
                 0.59060238 
               
               
                 ACPP 
                 0.338642571 
                 −0.25159625 
                 0.59023882 
               
               
                 WDFY3 
                 0.227156 
                 −0.36272518 
                 0.58988118 
               
               
                 SH2D1A 
                 −0.21825836 
                 0.37141254 
                 0.58967089 
               
               
                 UHRF1 
                 −0.20136976 
                 0.38829452 
                 0.58966428 
               
               
                 SMAD1 
                 0.287765043 
                 −0.29998998 
                 0.58775502 
               
               
                 FAM198B 
                 0.399518214 
                 −0.18798039 
                 0.58749861 
               
               
                 GGTA1P 
                 0.167619286 
                 −0.41747589 
                 0.58509518 
               
               
                 TC2N 
                 −0.26454679 
                 0.32010684 
                 0.58465362 
               
               
                 XLOC_014211 
                 0.011044229 
                 −0.57262589 
                 0.58367012 
               
               
                 DSCC1 
                 −0.2080774 
                 0.37472837 
                 0.58280577 
               
               
                 ETS1 
                 −0.30955529 
                 0.270924 
                 0.58047929 
               
               
                 RBM47 
                 0.349116429 
                 −0.23082243 
                 0.57993886 
               
               
                 SLC22A4 
                 0.244807786 
                 −0.33498348 
                 0.57979126 
               
               
                 UBASH3A 
                 −0.22020343 
                 0.35947714 
                 0.57968057 
               
               
                 CENPM 
                 −0.12387793 
                 0.4553175 
                 0.57919543 
               
               
                 TLR2 
                 0.444897714 
                 −0.13343436 
                 0.57833207 
               
               
                 DENND2D 
                 −0.17553779 
                 0.40131875 
                 0.57685654 
               
               
                 KIR2DS3 
                 −0.44095089 
                 0.13590208 
                 0.57685296 
               
               
                 CD163 
                 0.284595286 
                 −0.2914575 
                 0.57605279 
               
               
                 ZNF516 
                 0.341899714 
                 −0.23192736 
                 0.57382707 
               
               
                 MCM6 
                 −0.2673995 
                 0.30639182 
                 0.57379132 
               
               
                 MANSC1 
                 0.358897314 
                 −0.21444576 
                 0.57334307 
               
               
                 SLAMF7 
                 −0.23002979 
                 0.34091768 
                 0.57094746 
               
               
                 LAT 
                 −0.25102107 
                 0.318139 
                 0.56916007 
               
               
                 LAG3 
                 −0.15927029 
                 0.40855932 
                 0.56782961 
               
               
                 HOXB4 
                 −0.18688931 
                 0.38039065 
                 0.56727996 
               
               
                 CD96 
                 −0.29548743 
                 0.27057925 
                 0.56606668 
               
               
                 CYP1B1 
                 0.327229714 
                 −0.23867029 
                 0.5659 
               
               
                 WLS 
                 0.307582429 
                 −0.25765561 
                 0.56523804 
               
               
                 IL1R1 
                 0.240469186 
                 −0.32374119 
                 0.56421038 
               
               
                 CLEC4D 
                 0.360743286 
                 −0.20266225 
                 0.56340554 
               
               
                 SPOCK2 
                 −0.31221307 
                 0.25077596 
                 0.56298904 
               
               
                 MBOAT2 
                 0.183023886 
                 −0.37933214 
                 0.56235603 
               
               
                 SORT1 
                 0.327330143 
                 −0.23349196 
                 0.56082211 
               
               
                 KIF15 
                 −0.2177303 
                 0.34251854 
                 0.56024884 
               
               
                 CSF3R 
                 0.314176714 
                 −0.24596696 
                 0.56014368 
               
               
                 ITK 
                 −0.294615 
                 0.26540107 
                 0.56001607 
               
               
                 HNMT 
                 0.232559143 
                 −0.32677368 
                 0.55933282 
               
               
                 TIE1 
                 −0.32596631 
                 0.23241353 
                 0.55837984 
               
               
                 PRKACB 
                 −0.25575786 
                 0.30210143 
                 0.55785929 
               
               
                 CTIF 
                 0.221119357 
                 −0.33316384 
                 0.55428319 
               
               
                 CMTM2 
                 0.304997757 
                 −0.24824621 
                 0.55324397 
               
               
                 TBC1D9 
                 0.249669857 
                 −0.30340593 
                 0.55307579 
               
               
                 SPINT1 
                 0.333112 
                 −0.21939014 
                 0.55250214 
               
               
                 LBH 
                 −0.24474714 
                 0.30730196 
                 0.55204911 
               
               
                 KIF2C 
                 −0.18447456 
                 0.36618417 
                 0.55065873 
               
               
                 RUSC2 
                 0.293138643 
                 −0.25688511 
                 0.55002375 
               
               
                 GZMK 
                 −0.29421721 
                 0.25558446 
                 0.54980168 
               
               
                 CD320 
                 −0.3055135 
                 0.24368532 
                 0.54919882 
               
               
                 NCAM1 
                 −0.36557571 
                 0.18317471 
                 0.54875043 
               
               
                 TMTC2 
                 0.383854214 
                 −0.16442957 
                 0.54828379 
               
               
                 ASGR1 
                 0.3071775 
                 −0.24050568 
                 0.54768318 
               
               
                 FXYD6 
                 0.2127035 
                 −0.33376146 
                 0.54646496 
               
               
                 CKAP2L 
                 −0.45269184 
                 0.09253379 
                 0.54522564 
               
               
                 OXER1 
                 0.277124214 
                 −0.26681871 
                 0.54394293 
               
               
                 PYGL 
                 0.291343071 
                 −0.25168736 
                 0.54303043 
               
               
                 S1PR3 
                 0.391696929 
                 −0.15085943 
                 0.54255636 
               
               
                 KLF12 
                 −0.28678086 
                 0.25544246 
                 0.54222332 
               
               
                 ANXA6 
                 −0.29465314 
                 0.24746879 
                 0.54212193 
               
               
                 BCL6 
                 0.2903715 
                 −0.25103257 
                 0.54140407 
               
               
                 KLF5 
                 0.304956671 
                 −0.23619437 
                 0.54115104 
               
               
                 ENO2 
                 −0.2168789 
                 0.3236394 
                 0.5405183 
               
               
                 CD27 
                 −0.19185293 
                 0.347574 
                 0.53942693 
               
               
                 RBP7 
                 0.233317143 
                 −0.3036785 
                 0.53699564 
               
               
                 LOC100131490 
                 0.307047286 
                 −0.22785415 
                 0.53490144 
               
               
                 PTPN7 
                 −0.14836743 
                 0.38641711 
                 0.53478454 
               
               
                 HSD3B7 
                 0.517880143 
                 −0.01636599 
                 0.53424613 
               
               
                 ENTPD1 
                 0.217274 
                 −0.31624082 
                 0.53351482 
               
               
                 CENPK 
                 −0.21435279 
                 0.31886286 
                 0.53321564 
               
               
                 HAL 
                 0.242564014 
                 −0.29026531 
                 0.53282932 
               
               
                 GPR125 
                 −0.35057997 
                 0.18160325 
                 0.53218322 
               
               
                 LOC100289495 
                 0.292156871 
                 −0.23932099 
                 0.53147786 
               
               
                 RGL4 
                 −0.25457907 
                 0.27637839 
                 0.53095746 
               
               
                 CD8B 
                 −0.18820371 
                 0.34228961 
                 0.53049332 
               
               
                 DLEU1 
                 −0.2542565 
                 0.27575675 
                 0.53001325 
               
               
                 IL18R1 
                 −0.29159811 
                 0.23804614 
                 0.52964426 
               
               
                 DACH1 
                 0.337819657 
                 −0.19158154 
                 0.52940119 
               
               
                 CD8A 
                 −0.20150093 
                 0.32647193 
                 0.52797286 
               
               
                 E2F7 
                 −0.17232293 
                 0.35509695 
                 0.52741988 
               
               
                 TNFRSF10C 
                 0.297923571 
                 −0.2294785 
                 0.52740207 
               
               
                 TPX2 
                 −0.13689606 
                 0.39044902 
                 0.52734508 
               
               
                 TLR5 
                 0.291976214 
                 −0.23228036 
                 0.52425657 
               
               
                 CD5 
                 −0.24713221 
                 0.27680911 
                 0.52394132 
               
               
                 LOC387895 
                 −0.21919861 
                 0.30467782 
                 0.52387644 
               
               
                 STAB1 
                 0.346968429 
                 −0.17626314 
                 0.52323157 
               
               
                 ARRDC4 
                 0.2649595 
                 −0.25809061 
                 0.52305011 
               
               
                 LOC100506119 
                 0.294396 
                 −0.22709296 
                 0.52148896 
               
               
                 PTTG1 
                 −0.16892521 
                 0.35232025 
                 0.52124546 
               
               
                 SLC11A1 
                 0.253459714 
                 −0.26535271 
                 0.51881243 
               
               
                 PADI4 
                 0.1552918 
                 −0.36114964 
                 0.51644144 
               
               
                 VSTM1 
                 0.224156143 
                 −0.29217904 
                 0.51633518 
               
               
                 OPLAH 
                 0.3919475 
                 −0.12385536 
                 0.51580286 
               
               
                 PADI2 
                 0.241451286 
                 −0.27375796 
                 0.51520925 
               
               
                 SLC38A1 
                 −0.23439729 
                 0.28044493 
                 0.51484221 
               
               
                 CHST12 
                 −0.21952229 
                 0.29463357 
                 0.51415586 
               
               
                 ABLIM1 
                 −0.19230614 
                 0.3216015 
                 0.51390764 
               
               
                 CATSPER1 
                 0.230605429 
                 −0.28283689 
                 0.51344232 
               
               
                 CECR6 
                 0.309074 
                 −0.20393032 
                 0.51300432 
               
               
                 TLR6 
                 0.329424271 
                 −0.18336559 
                 0.51278986 
               
               
                 SIGLEC9 
                 0.370637257 
                 −0.14214075 
                 0.51277801 
               
               
                 HOXB2 
                 −0.20811757 
                 0.30407686 
                 0.51219443 
               
               
                 PLXDC2 
                 0.263196429 
                 −0.24899125 
                 0.51218768 
               
               
                 CREB5 
                 0.371664286 
                 −0.14022161 
                 0.51188589 
               
               
                 LOC100240735 
                 −0.11060654 
                 0.40042911 
                 0.51103565 
               
               
                 HAAO 
                 0.259200929 
                 −0.25162175 
                 0.51082268 
               
               
                 SLC8A1 
                 0.314681643 
                 −0.19613093 
                 0.51081257 
               
               
                 SIT1 
                 −0.10533347 
                 0.40479136 
                 0.51012484 
               
               
                 NUF2 
                 −0.11992784 
                 0.38920616 
                 0.509134 
               
               
                 BCL11B 
                 −0.20831614 
                 0.30066271 
                 0.50897886 
               
               
                 ALCAM 
                 0.356605357 
                 −0.15212025 
                 0.50872561 
               
               
                 BAHCC1 
                 0.191048329 
                 −0.31752701 
                 0.50857534 
               
               
                 LIPE 
                 −0.15525814 
                 0.35290129 
                 0.50815943 
               
               
                 BTLA 
                 0.063817314 
                 0.57193829 
                 0.50812097 
               
               
                 FAM169A 
                 −0.25192357 
                 0.25607334 
                 0.50799691 
               
               
                 RAD54L 
                 −0.18824769 
                 0.31971504 
                 0.50796273 
               
               
                 PSRC1 
                 0.332147143 
                 −0.17503814 
                 0.50718529 
               
               
                 PVR 
                 0.315551843 
                 −0.19133553 
                 0.50688737 
               
               
                 ICOS 
                 −0.17266071 
                 0.33378096 
                 0.50644168 
               
               
                 RAD51AP1 
                 −0.15825344 
                 0.34733869 
                 0.50559213 
               
               
                 RHOH 
                 −0.26363393 
                 0.24160936 
                 0.50524329 
               
               
                 CDA 
                 0.2362715 
                 −0.26884225 
                 0.50511375 
               
               
                 WDR67 
                 −0.19719257 
                 0.30739107 
                 0.50458364 
               
               
                 LEF1 
                 −0.23067757 
                 0.27287407 
                 0.50355164 
               
               
                 CD40LG 
                 −0.11914729 
                 0.38176804 
                 0.50091532 
               
               
                 CD93 
                 0.293264357 
                 −0.20619332 
                 0.49945768 
               
               
                 SLC16A5 
                 0.237339 
                 −0.26199429 
                 0.49933329 
               
               
                 FAM7A1 
                 0.207298014 
                 −0.29015196 
                 0.49744997 
               
               
                 HLX 
                 0.416788886 
                 −0.07845021 
                 0.4952391 
               
               
                 FZD1 
                 0.202783143 
                 −0.29188636 
                 0.4946695 
               
               
                 TCF7 
                 −0.2205655 
                 0.27400575 
                 0.49457125 
               
               
                 CLEC7A 
                 0.174408714 
                 −0.32003786 
                 0.49444657 
               
               
                 RASGRP4 
                 0.225120857 
                 −0.26896 
                 0.49408086 
               
               
                 S100Z 
                 0.278363429 
                 −0.21444639 
                 0.49280982 
               
               
                 SLC36A1 
                 0.362534357 
                 −0.12964436 
                 0.49217871 
               
               
                 IRAK3 
                 0.177265714 
                 −0.31149632 
                 0.48876204 
               
               
                 REPS2 
                 0.167204686 
                 −0.32112792 
                 0.48833261 
               
               
                 CDCA8 
                 −0.22826156 
                 0.2586116 
                 0.48687316 
               
               
                 CACNA2D3 
                 0.147184729 
                 −0.33929497 
                 0.4864797 
               
               
                 ATP9A 
                 −0.19487714 
                 0.29154147 
                 0.48641861 
               
               
                 TLR4 
                 0.283682 
                 −0.2026975 
                 0.4863795 
               
               
                 C5AR1 
                 0.088096071 
                 −0.39689704 
                 0.48499311 
               
               
                 JUP 
                 0.156214714 
                 −0.32745473 
                 0.48366944 
               
               
                 RNASE6 
                 0.242342286 
                 −0.24121675 
                 0.48355904 
               
               
                 SRD5A3 
                 0.1854806 
                 −0.29805416 
                 0.48353476 
               
               
                 VNN3 
                 0.089851229 
                 −0.39324561 
                 0.48309684 
               
               
                 NCF4 
                 0.287130143 
                 −0.19360982 
                 0.48073996 
               
               
                 CPAMD8 
                 0.213523286 
                 −0.26710254 
                 0.48062582 
               
               
                 IMPA2 
                 0.300314357 
                 −0.17852368 
                 0.47883804 
               
               
                 DUSP6 
                 0.405228286 
                 −0.07084136 
                 0.47606964 
               
               
                 SLC1A3 
                 0.399558143 
                 −0.07517946 
                 0.47473761 
               
               
                 STEAP4 
                 0.455998671 
                 −0.01826882 
                 0.47426749 
               
               
                 SIRPA 
                 0.300369143 
                 −0.17279968 
                 0.47316882 
               
               
                 PROK2 
                 0.391483571 
                 −0.081551 
                 0.47303457 
               
               
                 HOMER3 
                 0.268185429 
                 −0.20481154 
                 0.47299696 
               
               
                 PCNA 
                 −0.20712936 
                 0.26508754 
                 0.47221689 
               
               
                 LOC100506190 
                 0.264811214 
                 −0.20677068 
                 0.47158189 
               
               
                 LRRN3 
                 −0.14819123 
                 0.32129771 
                 0.46948894 
               
               
                 PELI3 
                 0.322259214 
                 −0.14640793 
                 0.46866714 
               
               
                 GLT1D1 
                 0.290086143 
                 −0.17845936 
                 0.4685455 
               
               
                 TRAT1 
                 −0.13320714 
                 0.33377432 
                 0.46698146 
               
               
                 IFNGR2 
                 0.221502643 
                 −0.24534257 
                 0.46684521 
               
               
                 VCAN 
                 0.32093 
                 −0.14525382 
                 0.46618382 
               
               
                 FBP1 
                 0.245210214 
                 −0.22077964 
                 0.46598986 
               
               
                 ATF3 
                 0.227069857 
                 −0.23813082 
                 0.46520068 
               
               
                 THEMIS 
                 −0.16147286 
                 0.303302 
                 0.46477486 
               
               
                 ALDH18A1 
                 −0.23830643 
                 0.22640319 
                 0.46470961 
               
               
                 PTAFR 
                 0.367958286 
                 −0.09622964 
                 0.46418793 
               
               
                 KIF14 
                 −0.12679421 
                 0.33703227 
                 0.46382649 
               
               
                 CCNE2 
                 −0.23386037 
                 0.22907573 
                 0.4629361 
               
               
                 KCNE3 
                 0.286638071 
                 −0.17603007 
                 0.46266814 
               
               
                 FIGNL1 
                 −0.39112519 
                 0.07060053 
                 0.46172571 
               
               
                 MNDA 
                 0.304120571 
                 −0.15425471 
                 0.45837529 
               
               
                 HP07349 
                 0.224252871 
                 −0.23307984 
                 0.45733271 
               
               
                 CPVL 
                 0.190771357 
                 −0.265568 
                 0.45633936 
               
               
                 CLDN23 
                 0.192351557 
                 −0.26357798 
                 0.45592954 
               
               
                 CASC5 
                 −0.0853667 
                 0.3705584 
                 0.4559251 
               
               
                 ITPR3 
                 −0.14814271 
                 0.30532818 
                 0.45347089 
               
               
                 RGL1 
                 0.292098071 
                 −0.16081871 
                 0.45291678 
               
               
                 TM6SF1 
                 0.172928171 
                 −0.27996275 
                 0.45289092 
               
               
                 SLC22A15 
                 0.256408929 
                 −0.19479271 
                 0.45120164 
               
               
                 BMP2K 
                 0.340658 
                 −0.11052889 
                 0.45118689 
               
               
                 RORA 
                 −0.31763243 
                 0.13335904 
                 0.45099146 
               
               
                 ENPP4 
                 −0.22791429 
                 0.22254214 
                 0.45045643 
               
               
                 MCM3 
                 −0.1810385 
                 0.26783636 
                 0.44887486 
               
               
                 C3AR1 
                 0.236919 
                 −0.21150971 
                 0.44842871 
               
               
                 BCL2 
                 −0.19330557 
                 0.25353029 
                 0.44683586 
               
               
                 LRG1 
                 0.218137786 
                 −0.22740541 
                 0.44554319 
               
               
                 NACC2 
                 0.184041143 
                 −0.26108996 
                 0.44513111 
               
               
                 GAS2L1 
                 0.211091286 
                 −0.23393936 
                 0.44503064 
               
               
                 RASA3 
                 −0.22732943 
                 0.21659846 
                 0.44392789 
               
               
                 CLEC12A 
                 0.203698143 
                 −0.23979146 
                 0.44348961 
               
               
                 CENPO 
                 −0.15994436 
                 0.28329822 
                 0.44324258 
               
               
                 PLBD1 
                 0.308567143 
                 −0.13360864 
                 0.44217579 
               
               
                 IFNGR1 
                 0.206392429 
                 −0.23572343 
                 0.44211586 
               
               
                 AURKA 
                 −0.06510166 
                 0.376225 
                 0.44132666 
               
               
                 FLT3LG 
                 −0.24143607 
                 0.19988446 
                 0.44132054 
               
               
                 CYFIP1 
                 0.278670429 
                 −0.16178471 
                 0.44045514 
               
               
                 KLK3 
                 0.317315214 
                 −0.12297611 
                 0.44029133 
               
               
                 DGAT2 
                 0.383776214 
                 −0.05560687 
                 0.43938309 
               
               
                 KIAA1598 
                 0.196053071 
                 −0.24282182 
                 0.43887489 
               
               
                 LCK 
                 −0.19461843 
                 0.24340629 
                 0.43802471 
               
               
                 TRIP13 
                 −0.11449776 
                 0.32300382 
                 0.43750158 
               
               
                 DIRC2 
                 0.209791143 
                 −0.22762654 
                 0.43741768 
               
               
                 RAB13 
                 0.253744629 
                 −0.18336525 
                 0.43710988 
               
               
                 LRRC4 
                 0.381947829 
                 −0.05513704 
                 0.43708487 
               
               
                 LOC100130458 
                 0.116891071 
                 0.55288541 
                 0.43599434 
               
               
                 MAL 
                 −0.16839007 
                 0.26727318 
                 0.43566325 
               
               
                 TNS3 
                 0.278597929 
                 −0.1568785 
                 0.43547643 
               
               
                 LPCAT2 
                 0.168471571 
                 −0.26599285 
                 0.43446442 
               
               
                 DENND1A 
                 0.187873214 
                 −0.24632518 
                 0.43419839 
               
               
                 PPP1R32 
                 0.246556914 
                 −0.18738554 
                 0.43394245 
               
               
                 LRRK2 
                 0.179330429 
                 −0.25345061 
                 0.43278104 
               
               
                 MARCH1 
                 0.304293571 
                 −0.12841868 
                 0.43271225 
               
               
                 CSDA 
                 0.174335429 
                 −0.25818643 
                 0.43252186 
               
               
                 GATA3 
                 −0.15800157 
                 0.27439999 
                 0.43240156 
               
               
                 MGST1 
                 0.260136214 
                 −0.171845 
                 0.43198121 
               
               
                 CAMK4 
                 −0.21311271 
                 0.21834766 
                 0.43146038 
               
               
                 MCM8 
                 −0.16223123 
                 0.26906441 
                 0.43129564 
               
               
                 XLOC_014161 
                 0.159774714 
                 −0.27144611 
                 0.43122082 
               
               
                 COPG2 
                 0.243141886 
                 −0.18801444 
                 0.43115633 
               
               
                 TP53I3 
                 0.221867429 
                 −0.20887982 
                 0.43074725 
               
               
                 EMR2 
                 0.165954643 
                 −0.26454793 
                 0.43050257 
               
               
                 VNN1 
                 0.249032214 
                 −0.1813005 
                 0.43033271 
               
               
                 KIF11 
                 −0.15487474 
                 0.27468888 
                 0.42956362 
               
               
                 MSH2 
                 −0.117764 
                 0.31093821 
                 0.42870221 
               
               
                 WEE1 
                 −0.15173171 
                 0.27648444 
                 0.42821615 
               
               
                 P2RY13 
                 0.317733 
                 −0.10982325 
                 0.42755625 
               
               
                 HELB 
                 −0.11619527 
                 0.31125171 
                 0.42744698 
               
               
                 TRANK1 
                 −0.12740821 
                 0.29891346 
                 0.42632168 
               
               
                 CCR1 
                 0.300865143 
                 −0.12532832 
                 0.42619346 
               
               
                 LOC100505921 
                 −0.15721229 
                 0.26829006 
                 0.42550234 
               
               
                 LHFPL2 
                 0.341473714 
                 −0.08390814 
                 0.42538186 
               
               
                 SLC24A4 
                 0.199079071 
                 −0.22578986 
                 0.42486893 
               
               
                 LTF 
                 0.763298829 
                 0.33854093 
                 0.4247579 
               
               
                 FCRL5 
                 0.095907571 
                 0.51954987 
                 0.4236423 
               
               
                 PCDH9 
                 0.471096286 
                 0.89444049 
                 0.42334421 
               
               
                 RBL1 
                 −0.1193045 
                 0.30341787 
                 0.42272237 
               
               
                 MAD2L1 
                 −0.1968512 
                 0.22556866 
                 0.42241986 
               
               
                 SHCBP1 
                 −0.18099769 
                 0.24105691 
                 0.4220546 
               
               
                 FOLR3 
                 0.200585357 
                 −0.22105254 
                 0.42163789 
               
               
                 ALDH2 
                 0.138676143 
                 −0.28251946 
                 0.42119561 
               
               
                 TGFBI 
                 0.218445357 
                 −0.20263325 
                 0.42107861 
               
               
                 LY96 
                 0.252913286 
                 −0.16756939 
                 0.42048268 
               
               
                 GLB1L 
                 0.183340414 
                 −0.23602441 
                 0.41936483 
               
               
                 NELL2 
                 −0.17102343 
                 0.24754086 
                 0.41856429 
               
               
                 SCPEP1 
                 0.205820571 
                 −0.21247036 
                 0.41829093 
               
               
                 MYBL2 
                 −0.24317244 
                 0.17455584 
                 0.41772829 
               
               
                 DYSF 
                 0.359312929 
                 −0.05823496 
                 0.41754789 
               
               
                 NAIP 
                 0.3178735 
                 −0.09899714 
                 0.41687064 
               
               
                 CD36 
                 0.308184 
                 −0.10792732 
                 0.41611132 
               
               
                 LY86 
                 0.172096714 
                 −0.24375036 
                 0.41584707 
               
               
                 PRAM1 
                 0.206100857 
                 −0.20934879 
                 0.41544964 
               
               
                 IL7R 
                 −0.07469257 
                 0.33924354 
                 0.41393611 
               
               
                 PDLIM7 
                 0.302697929 
                 −0.11055939 
                 0.41325732 
               
               
                 MS4A4A 
                 0.334755214 
                 −0.07767843 
                 0.41243364 
               
               
                 FCGR2A 
                 0.195130571 
                 −0.21716389 
                 0.41229446 
               
               
                 DOCK5 
                 0.142947243 
                 −0.26929281 
                 0.41224005 
               
               
                 RAB34 
                 0.203238143 
                 −0.20877086 
                 0.412009 
               
               
                 CYBRD1 
                 0.111162 
                 −0.30075943 
                 0.41192143 
               
               
                 RNASE3 
                 0.268917 
                 −0.14296371 
                 0.41188071 
               
               
                 HPSE 
                 0.277266714 
                 −0.13327411 
                 0.41054082 
               
               
                 ELANE 
                 0.113760757 
                 −0.29674864 
                 0.41050939 
               
               
                 RNF24 
                 0.273337871 
                 −0.13560884 
                 0.40894671 
               
               
                 MYADM 
                 0.203808571 
                 −0.20445664 
                 0.40826521 
               
               
                 SMARCD3 
                 0.171004 
                 −0.23642889 
                 0.40743289 
               
               
                 MS4A6A 
                 0.219724714 
                 −0.18766754 
                 0.40739225 
               
               
                 LILRB3 
                 0.219028571 
                 −0.18677839 
                 0.40580696 
               
               
                 LPPR2 
                 0.204843857 
                 −0.19941179 
                 0.40425565 
               
               
                 FEN1 
                 −0.11046916 
                 0.29375101 
                 0.40422017 
               
               
                 TLR8 
                 0.258494357 
                 −0.14398514 
                 0.4024795 
               
               
                 GPR171 
                 0.046738214 
                 0.44807932 
                 0.40134111 
               
               
                 PECAM1 
                 0.166314929 
                 −0.23346854 
                 0.39978346 
               
               
                 RENBP 
                 0.1793322 
                 −0.21994659 
                 0.39927879 
               
               
                 IL18 
                 0.094394 
                 −0.30436183 
                 0.39875583 
               
               
                 CFD 
                 0.095564857 
                 −0.30247307 
                 0.39803793 
               
               
                 ADAP2 
                 0.191108 
                 −0.20639968 
                 0.39750768 
               
               
                 PRRG4 
                 0.234579614 
                 −0.16231581 
                 0.39689543 
               
               
                 LMO2 
                 0.316302143 
                 −0.08048718 
                 0.39678932 
               
               
                 RPA2 
                 −0.15216443 
                 0.24319079 
                 0.39535521 
               
               
                 IMMP1L 
                 −0.24381664 
                 0.1514269 
                 0.39524354 
               
               
                 RAB31 
                 0.198269429 
                 −0.19655504 
                 0.39482446 
               
               
                 MCTP1 
                 0.189488857 
                 −0.20293439 
                 0.39242325 
               
               
                 BLVRB 
                 0.186325571 
                 −0.20505411 
                 0.39137968 
               
               
                 SLAMF1 
                 −0.05256957 
                 0.33766054 
                 0.39023011 
               
               
                 SRGN 
                 0.162264714 
                 −0.22679493 
                 0.38905964 
               
               
                 KCTD12 
                 0.256325714 
                 −0.13257457 
                 0.38890029 
               
               
                 TIMP2 
                 0.211432571 
                 −0.17675525 
                 0.38818782 
               
               
                 EOMES 
                 −0.15878157 
                 0.22841004 
                 0.38719161 
               
               
                 SLC7A7 
                 0.159725571 
                 −0.22638171 
                 0.38610729 
               
               
                 LILRA3 
                 0.200592857 
                 −0.18353643 
                 0.38412929 
               
               
                 SIGLEC15 
                 0.251399786 
                 −0.13264211 
                 0.38404189 
               
               
                 DRAM1 
                 0.315899357 
                 −0.06714721 
                 0.38304657 
               
               
                 CDCA3 
                 −0.09058453 
                 0.29209835 
                 0.38268288 
               
               
                 SULF2 
                 0.153704714 
                 −0.22867929 
                 0.382384 
               
               
                 LGALS3 
                 0.190961214 
                 −0.19122154 
                 0.38218275 
               
               
                 NLRP12 
                 0.224418143 
                 −0.15755489 
                 0.38197304 
               
               
                 CD33 
                 0.155254 
                 −0.22667521 
                 0.38192921 
               
               
                 ITPRIPL2 
                 0.283875571 
                 −0.09768686 
                 0.38156243 
               
               
                 CDC20 
                 −0.17666284 
                 0.20478786 
                 0.3814507 
               
               
                 TMEM127 
                 0.144628571 
                 −0.23526511 
                 0.37989368 
               
               
                 GIMAP7 
                 0.036056571 
                 0.41435014 
                 0.37829357 
               
               
                 CPPED1 
                 0.137228929 
                 −0.24017332 
                 0.37740225 
               
               
                 FANCI 
                 −0.16702414 
                 0.21036312 
                 0.37738726 
               
               
                 AKIRIN2 
                 0.155994857 
                 −0.22050457 
                 0.37649943 
               
               
                 S100A12 
                 0.309248143 
                 −0.06721379 
                 0.37646193 
               
               
                 STK39 
                 −0.11245929 
                 0.26374314 
                 0.37620243 
               
               
                 CLEC10A 
                 0.180977071 
                 −0.19424675 
                 0.37522382 
               
               
                 CD68 
                 0.146906 
                 −0.22801989 
                 0.37492589 
               
               
                 E2F5 
                 0.006467957 
                 0.38078871 
                 0.37432075 
               
               
                 CHST15 
                 0.246691429 
                 −0.12753179 
                 0.37422321 
               
               
                 ZNF668 
                 0.118555714 
                 −0.25523732 
                 0.37379304 
               
               
                 CLEC4A 
                 0.180520643 
                 −0.19312632 
                 0.37364696 
               
               
                 OSCAR 
                 0.262092714 
                 −0.11077871 
                 0.37287143 
               
               
                 CD28 
                 −0.21509714 
                 0.15756741 
                 0.37266456 
               
               
                 CSTA 
                 0.158350214 
                 −0.21139846 
                 0.36974868 
               
               
                 TMEM64 
                 −0.2599964 
                 0.10957631 
                 0.36957271 
               
               
                 GLT25D1 
                 0.16811 
                 −0.20127571 
                 0.36938571 
               
               
                 LGALS2 
                 0.183200857 
                 −0.18592343 
                 0.36912429 
               
               
                 PFKFB4 
                 0.160700929 
                 −0.20834925 
                 0.36905018 
               
               
                 AMICA1 
                 0.227419571 
                 −0.14141196 
                 0.36883154 
               
               
                 STX10 
                 0.202234786 
                 −0.16646264 
                 0.36869743 
               
               
                 SYK 
                 0.196623286 
                 −0.1717975 
                 0.36842079 
               
               
                 AGAP2 
                 −0.137432 
                 0.23078254 
                 0.36821454 
               
               
                 ACSL1 
                 0.160613357 
                 −0.20691032 
                 0.36752368 
               
               
                 RFC4 
                 −0.08400186 
                 0.28309346 
                 0.36709532 
               
               
                 IGSF6 
                 0.225586 
                 −0.14143814 
                 0.36702414 
               
               
                 CSF2RA 
                 0.2099765 
                 −0.15688386 
                 0.36686036 
               
               
                 DAPK1 
                 0.134109729 
                 −0.23158734 
                 0.36569707 
               
               
                 CR2 
                 0.116018943 
                 0.48136556 
                 0.36534662 
               
               
                 CARD9 
                 0.140085929 
                 −0.22507043 
                 0.36515636 
               
               
                 ZNF790 
                 −0.05887033 
                 0.30589269 
                 0.36476301 
               
               
                 NCF2 
                 0.175950286 
                 −0.18565439 
                 0.36160468 
               
               
                 MRFAP1L1 
                 −0.11274821 
                 0.24734171 
                 0.36008993 
               
               
                 AURKB 
                 −0.3572037 
                 0.00276418 
                 0.35996788 
               
               
                 ANPEP 
                 0.270537786 
                 −0.08937875 
                 0.35991654 
               
               
                 LTBR 
                 0.143410857 
                 −0.21426214 
                 0.357673 
               
               
                 SLC15A3 
                 0.143413786 
                 −0.21419907 
                 0.35761286 
               
               
                 GNB4 
                 0.182312143 
                 −0.17504436 
                 0.3573565 
               
               
                 PRKAR1B 
                 −0.13330653 
                 0.2240327 
                 0.35733923 
               
               
                 MEGF9 
                 0.229724 
                 −0.1275625 
                 0.3572865 
               
               
                 ABCD1 
                 0.162001429 
                 −0.19449646 
                 0.35649789 
               
               
                 S100A11 
                 0.173434071 
                 −0.18187364 
                 0.35530771 
               
               
                 PDGFC 
                 0.169980143 
                 −0.185277 
                 0.35525714 
               
               
                 ATAD1 
                 −0.06876736 
                 0.28555168 
                 0.35431904 
               
               
                 SIGLEC1 
                 0.323350029 
                 −0.03061627 
                 0.3539663 
               
               
                 TNFSF13 
                 0.118673786 
                 −0.2346925 
                 0.35336629 
               
               
                 CD302 
                 0.112564286 
                 −0.24046182 
                 0.35302611 
               
               
                 ARHGEF10L 
                 0.140632286 
                 −0.211631 
                 0.35226329 
               
               
                 HHEX 
                 0.216942429 
                 −0.1352445 
                 0.35218693 
               
               
                 KRT23 
                 0.182163071 
                 −0.16969303 
                 0.3518561 
               
               
                 ESCO2 
                 0.108076843 
                 0.45909527 
                 0.35101843 
               
               
                 RARRES3 
                 −0.19102486 
                 0.15946211 
                 0.35048696 
               
               
                 NCEH1 
                 0.217908429 
                 −0.13163246 
                 0.34954089 
               
               
                 ANO10 
                 0.183057 
                 −0.16613929 
                 0.34919629 
               
               
                 RAB32 
                 0.160565929 
                 −0.18859543 
                 0.34916136 
               
               
                 FCGRT 
                 0.128174071 
                 −0.22095846 
                 0.34913254 
               
               
                 C3orf26 
                 −0.20833593 
                 0.1404875 
                 0.34882343 
               
               
                 ARAP3 
                 0.172906214 
                 −0.17539179 
                 0.348298 
               
               
                 TBXAS1 
                 0.119282857 
                 −0.22890532 
                 0.34818818 
               
               
                 FPR2 
                 0.283766857 
                 −0.06392204 
                 0.34768889 
               
               
                 AGTRAP 
                 0.174739214 
                 −0.17160118 
                 0.34634039 
               
               
                 FGD4 
                 0.153042571 
                 −0.1932215 
                 0.34626407 
               
               
                 CCR7 
                 −0.11832114 
                 0.22720743 
                 0.34552857 
               
               
                 CSF1R 
                 0.110029357 
                 −0.23533893 
                 0.34536829 
               
               
                 TTPAL 
                 −0.09728186 
                 0.24782729 
                 0.34510914 
               
               
                 TLR7 
                 0.252227071 
                 −0.09285861 
                 0.34508568 
               
               
                 LILRA5 
                 0.118514429 
                 −0.22476404 
                 0.34327846 
               
               
                 KCNJ15 
                 0.456193143 
                 0.11300498 
                 0.34318816 
               
               
                 HDDC2 
                 −0.19240571 
                 0.15017121 
                 0.34257693 
               
               
                 CENPE 
                 −0.06459184 
                 0.27777848 
                 0.34237032 
               
               
                 DEPDC1B 
                 0.086165729 
                 0.42821411 
                 0.34204839 
               
               
                 F13A1 
                 0.281931357 
                 −0.05990064 
                 0.341832 
               
               
                 TKT 
                 0.178549571 
                 −0.16315625 
                 0.34170582 
               
               
                 SIAE 
                 0.302025386 
                 −0.03965144 
                 0.34167682 
               
               
                 PLA2G7 
                 0.155596357 
                 −0.18373108 
                 0.33932744 
               
               
                 HVCN1 
                 0.196912286 
                 −0.142292 
                 0.33920429 
               
               
                 VIM 
                 0.256285714 
                 −0.08262636 
                 0.33891207 
               
               
                 SMYD3 
                 −0.23754843 
                 0.10115771 
                 0.33870614 
               
               
                 LILRB1 
                 0.243770357 
                 −0.09430354 
                 0.33807389 
               
               
                 SLC46A2 
                 0.246823986 
                 −0.09115934 
                 0.33798332 
               
               
                 CDC25A 
                 −0.24464234 
                 0.09325778 
                 0.33790012 
               
               
                 LOC93622 
                 −0.19243486 
                 0.14486786 
                 0.33730271 
               
               
                 TFEC 
                 0.142966643 
                 −0.19367514 
                 0.33664179 
               
               
                 BPI 
                 0.252416714 
                 −0.08360925 
                 0.33602596 
               
               
                 MARCO 
                 0.262151 
                 −0.07320732 
                 0.33535832 
               
               
                 PID1 
                 0.163599786 
                 −0.17149768 
                 0.33509746 
               
               
                 IKZF1 
                 −0.18795293 
                 0.14708693 
                 0.33503986 
               
               
                 GPATCH4 
                 −0.11773636 
                 0.21681007 
                 0.33454643 
               
               
                 BTN3A2 
                 −0.11306943 
                 0.22099021 
                 0.33405964 
               
               
                 LY9 
                 −0.14916079 
                 0.18474139 
                 0.33390218 
               
               
                 TTC7A 
                 0.158075857 
                 −0.17509714 
                 0.333173 
               
               
                 SERPINA1 
                 0.18943 
                 −0.14302168 
                 0.33245168 
               
               
                 AKTIP 
                 −0.10950264 
                 0.22220111 
                 0.33170375 
               
               
                 SPAG5 
                 −0.09952629 
                 0.23141186 
                 0.33093814 
               
               
                 IL1RN 
                 0.278950857 
                 −0.05174964 
                 0.3307005 
               
               
                 ATG7 
                 0.205422143 
                 −0.12514593 
                 0.33056807 
               
               
                 PSAP 
                 0.121625143 
                 −0.20859004 
                 0.33021518 
               
               
                 PGD 
                 0.230786857 
                 −0.09899668 
                 0.32978354 
               
               
                 CFP 
                 0.128877286 
                 −0.20084218 
                 0.32971946 
               
               
                 HK3 
                 0.237489714 
                 −0.09144721 
                 0.32893693 
               
               
                 SIGLEC7 
                 0.126815571 
                 −0.20193039 
                 0.32874596 
               
               
                 GRN 
                 0.207244143 
                 −0.120798 
                 0.32804214 
               
               
                 QSOX1 
                 0.183818214 
                 −0.14306671 
                 0.32688493 
               
               
                 UBE2D1 
                 0.176726357 
                 −0.14988214 
                 0.3266085 
               
               
                 HEBP2 
                 0.152510143 
                 −0.17333325 
                 0.32584339 
               
               
                 BCL2A1 
                 0.123345286 
                 −0.20224129 
                 0.32558657 
               
               
                 BCKDK 
                 0.185639714 
                 −0.13980589 
                 0.32544561 
               
               
                 MBOAT7 
                 0.207825071 
                 −0.11713857 
                 0.32496364 
               
               
                 ALOX5 
                 0.187580429 
                 −0.13714918 
                 0.32472961 
               
               
                 NLRC4 
                 0.360432571 
                 0.03675132 
                 0.32368125 
               
               
                 PLD3 
                 0.123464071 
                 −0.19904129 
                 0.32250536 
               
               
                 HENMT1 
                 −0.11908886 
                 0.20285339 
                 0.32194225 
               
               
                 C20orf194 
                 0.155664857 
                 −0.16459157 
                 0.32025643 
               
               
                 NOD2 
                 0.174258286 
                 −0.14543357 
                 0.31969186 
               
               
                 QPCT 
                 0.17933 
                 −0.13977096 
                 0.31910096 
               
               
                 MCM7 
                 −0.14002314 
                 0.17880614 
                 0.31882929 
               
               
                 PTPRK 
                 0.204003429 
                 0.5226765 
                 0.31867307 
               
               
                 RNASE2 
                 0.272614786 
                 −0.04589457 
                 0.31850936 
               
               
                 NPC2 
                 0.116562286 
                 −0.20121646 
                 0.31777875 
               
               
                 CD9 
                 0.173752229 
                 −0.14344236 
                 0.31719459 
               
               
                 BRI3 
                 0.153947429 
                 −0.16324436 
                 0.31719179 
               
               
                 TMEM55A 
                 0.1876985 
                 −0.12856771 
                 0.31626621 
               
               
                 MPEG1 
                 0.145838357 
                 −0.17023204 
                 0.31607039 
               
               
                 TPCN1 
                 0.124342714 
                 −0.19137939 
                 0.31572211 
               
               
                 GAA 
                 0.162399571 
                 −0.15325996 
                 0.31565954 
               
               
                 DICER1 
                 0.234740429 
                 −0.08078946 
                 0.31552989 
               
               
                 TTYH3 
                 0.096881929 
                 −0.2184615 
                 0.31534343 
               
               
                 RNF130 
                 0.1476985 
                 −0.16759736 
                 0.31529586 
               
               
                 SAMD13 
                 0.469062286 
                 0.1543228 
                 0.31473949 
               
               
                 SLCO4C1 
                 −0.03990057 
                 0.27477227 
                 0.31467284 
               
               
                 CD14 
                 0.206280286 
                 −0.10837093 
                 0.31465121 
               
               
                 TTLL4 
                 0.177558143 
                 −0.13611734 
                 0.31367548 
               
               
                 FZD5 
                 0.373442386 
                 0.06099209 
                 0.31245029 
               
               
                 MAP3K3 
                 0.145047643 
                 −0.16736718 
                 0.31241482 
               
               
                 CTSB 
                 0.134683429 
                 −0.17736096 
                 0.31204439 
               
               
                 SMC2 
                 −0.12230134 
                 0.18895004 
                 0.31125139 
               
               
                 TMEM51 
                 0.281504429 
                 −0.02969702 
                 0.31120145 
               
               
                 IL21R 
                 −0.10318271 
                 0.20682311 
                 0.31000582 
               
               
                 VNN2 
                 0.238745286 
                 −0.07096643 
                 0.30971171 
               
               
                 BST1 
                 0.122712 
                 −0.18649204 
                 0.30920404 
               
               
                 NCAPG2 
                 −0.1336442 
                 0.17517352 
                 0.30881772 
               
               
                 GPX1 
                 0.194986 
                 −0.11377771 
                 0.30876371 
               
               
                 KCNJ2 
                 0.535975657 
                 0.22722416 
                 0.30875149 
               
               
                 FES 
                 0.202224429 
                 −0.10634068 
                 0.30856511 
               
               
                 DPP4 
                 −0.09439186 
                 0.21415932 
                 0.30855118 
               
               
                 BTN3A1 
                 −0.11011443 
                 0.19807043 
                 0.30818486 
               
               
                 AZU1 
                 0.223116043 
                 −0.0846731 
                 0.30778914 
               
               
                 GMNN 
                 −0.12069914 
                 0.18704521 
                 0.30774436 
               
               
                 GSN 
                 0.131577214 
                 −0.175545 
                 0.30712221 
               
               
                 CPEB4 
                 0.163479571 
                 −0.14039339 
                 0.30387296 
               
               
                 IL12RB2 
                 −0.10310389 
                 0.19992615 
                 0.30303004 
               
               
                 AIF1 
                 0.118723714 
                 −0.18273164 
                 0.30145536 
               
               
                 APITD1 
                 −0.07477697 
                 0.22439621 
                 0.29917318 
               
               
                 BTK 
                 0.156705857 
                 −0.14215411 
                 0.29885996 
               
               
                 NRM 
                 0.089331214 
                 −0.20934621 
                 0.29867743 
               
               
                 MS4A1 
                 0.079191429 
                 0.37782723 
                 0.2986358 
               
               
                 MFSD1 
                 0.1568815 
                 −0.14147314 
                 0.29835464 
               
               
                 REXO4 
                 −0.1100965 
                 0.18783189 
                 0.29792839 
               
               
                 SIGLEC5 
                 0.191262986 
                 −0.10654275 
                 0.29780574 
               
               
                 GRWD1 
                 −0.10044229 
                 0.19704314 
                 0.29748543 
               
               
                 TMEM176A 
                 0.119317543 
                 −0.17772454 
                 0.29704208 
               
               
                 CCRL2 
                 0.081377429 
                 −0.21558271 
                 0.29696014 
               
               
                 EBF1 
                 0.100721286 
                 0.39671951 
                 0.29599823 
               
               
                 BRWD3 
                 0.1948784 
                 −0.1009656 
                 0.295844 
               
               
                 ZWILCH 
                 −0.10540566 
                 0.18996072 
                 0.29536638 
               
               
                 CDK2 
                 −0.12162653 
                 0.1736169 
                 0.29524343 
               
               
                 KLHL18 
                 0.171266857 
                 −0.12381368 
                 0.29508054 
               
               
                 ZNF367 
                 −0.00573039 
                 0.28932663 
                 0.29505701 
               
               
                 NFKBIA 
                 0.161213143 
                 −0.13376807 
                 0.29498121 
               
               
                 DPYD 
                 0.156869357 
                 −0.138058 
                 0.29492736 
               
               
                 ZFP36 
                 0.175877571 
                 −0.11895879 
                 0.29483636 
               
               
                 F5 
                 0.250602129 
                 −0.04361346 
                 0.29421559 
               
               
                 SMEK2 
                 −0.01661771 
                 0.27744939 
                 0.29406711 
               
               
                 GINS4 
                 −0.067823 
                 0.22594522 
                 0.29376822 
               
               
                 CD22 
                 0.008552886 
                 0.30209261 
                 0.29353973 
               
               
                 SLC27A3 
                 0.176830214 
                 −0.11502671 
                 0.29185693 
               
               
                 CDC7 
                 0.053590786 
                 0.34504874 
                 0.29145795 
               
               
                 GCA 
                 0.309009643 
                 0.01764846 
                 0.29136118 
               
               
                 SIRPB1 
                 0.129623429 
                 −0.16148064 
                 0.29110407 
               
               
                 CDC42BPB 
                 0.1311075 
                 −0.159489 
                 0.2905965 
               
               
                 SPNS1 
                 0.146933571 
                 −0.14342543 
                 0.290359 
               
               
                 TSPAN15 
                 0.066098514 
                 0.35645661 
                 0.29035809 
               
               
                 CST3 
                 0.08667 
                 −0.20325982 
                 0.28992982 
               
               
                 PLXNB2 
                 0.120476429 
                 −0.16928714 
                 0.28976357 
               
               
                 RASSF4 
                 0.125179857 
                 −0.16421807 
                 0.28939793 
               
               
                 LOC100288602 
                 −0.08719464 
                 0.20071625 
                 0.28791089 
               
               
                 PKIA 
                 −0.07867879 
                 0.20817289 
                 0.28685168 
               
               
                 C9orf7 
                 0.183859714 
                 −0.10165007 
                 0.28550979 
               
               
                 TLR1 
                 0.216556 
                 −0.06819975 
                 0.28475575 
               
               
                 CEP76 
                 −0.05635327 
                 0.22814923 
                 0.2845025 
               
               
                 PRKCD 
                 0.195118357 
                 −0.08932918 
                 0.28444754 
               
               
                 CD1A 
                 0.170681086 
                 −0.11343859 
                 0.28411968 
               
               
                 PLEC 
                 0.205366286 
                 −0.07738589 
                 0.28275218 
               
               
                 LILRA6 
                 0.205201286 
                 −0.07564396 
                 0.28084525 
               
               
                 RCCD1 
                 −0.128903 
                 0.15155211 
                 0.28045511 
               
               
                 DHFR 
                 0.008705214 
                 0.28889754 
                 0.28019233 
               
               
                 SLC31A2 
                 0.201080214 
                 −0.07896014 
                 0.28004036 
               
               
                 PRMT1 
                 −0.14745857 
                 0.1323615 
                 0.27982007 
               
               
                 NFAM1 
                 0.149785286 
                 −0.12988161 
                 0.27966689 
               
               
                 ADD3 
                 −0.10361586 
                 0.17557793 
                 0.27919379 
               
               
                 AOAH 
                 0.112956857 
                 −0.16581843 
                 0.27877529 
               
               
                 TYROBP 
                 0.129111286 
                 −0.1495625 
                 0.27867379 
               
               
                 LILRA2 
                 0.083337857 
                 −0.19414179 
                 0.27747964 
               
               
                 FGR 
                 0.139595571 
                 −0.13783404 
                 0.27742961 
               
               
                 NCF1 
                 0.188341643 
                 −0.08884914 
                 0.27719079 
               
               
                 RACGAP1 
                 −0.04545993 
                 0.23033114 
                 0.27579106 
               
               
                 SGOL2 
                 −0.0736771 
                 0.20052546 
                 0.27420256 
               
               
                 GPR84 
                 0.155422786 
                 −0.11842584 
                 0.27384863 
               
               
                 FCRL1 
                 0.0387364 
                 0.31105258 
                 0.27231618 
               
               
                 NINJ2 
                 0.135472714 
                 −0.13671911 
                 0.27219182 
               
               
                 MPP1 
                 0.160403571 
                 −0.11111929 
                 0.27152286 
               
               
                 FPR1 
                 0.155853714 
                 −0.11522661 
                 0.27108032 
               
               
                 PITPNB 
                 −0.13456043 
                 0.13234711 
                 0.26690754 
               
               
                 RAD21 
                 −0.10346771 
                 0.16341486 
                 0.26688257 
               
               
                 GRINA 
                 0.075730143 
                 −0.18943504 
                 0.26516518 
               
               
                 HDAC8 
                 0.157113357 
                 −0.10713729 
                 0.26425064 
               
               
                 GNG10 
                 0.211676929 
                 −0.05257 
                 0.26424693 
               
               
                 CD19 
                 0.018627857 
                 0.28259068 
                 0.26396282 
               
               
                 EMILIN2 
                 0.132286 
                 −0.13159482 
                 0.26388082 
               
               
                 CCR2 
                 0.4050525 
                 0.14351464 
                 0.26153786 
               
               
                 MTO1 
                 −0.03094193 
                 0.23026036 
                 0.26120229 
               
               
                 LILRB2 
                 0.108566571 
                 −0.15243307 
                 0.26099964 
               
               
                 DOK3 
                 0.188393143 
                 −0.07252104 
                 0.26091418 
               
               
                 ACTN1 
                 0.223709071 
                 −0.03714046 
                 0.26084954 
               
               
                 MKI67 
                 −0.02859244 
                 0.23207986 
                 0.2606723 
               
               
                 RANGAP1 
                 −0.12530014 
                 0.13451096 
                 0.25981111 
               
               
                 NPDC1 
                 −0.047562 
                 0.21147393 
                 0.25903593 
               
               
                 SPI1 
                 0.122915286 
                 −0.13446354 
                 0.25737882 
               
               
                 NEDD1 
                 −0.11064514 
                 0.1462275 
                 0.25687264 
               
               
                 PRIM2 
                 −0.03703164 
                 0.21902236 
                 0.256054 
               
               
                 HCK 
                 0.145662 
                 −0.11017818 
                 0.25584018 
               
               
                 PRIM1 
                 −0.05954271 
                 0.19627593 
                 0.25581864 
               
               
                 FCN1 
                 0.148124571 
                 −0.10727114 
                 0.25539571 
               
               
                 TIMELESS 
                 −0.05553264 
                 0.1994745 
                 0.25500714 
               
               
                 DSE 
                 0.174959714 
                 −0.07939089 
                 0.25435061 
               
               
                 SAE1 
                 −0.14703571 
                 0.10684029 
                 0.253876 
               
               
                 S100A8 
                 0.180040286 
                 −0.07339386 
                 0.25343414 
               
               
                 TUBG1 
                 0.043387857 
                 0.29674596 
                 0.25335811 
               
               
                 ATPAF2 
                 0.141355 
                 −0.11012036 
                 0.25147536 
               
               
                 ZNF131 
                 −0.14210886 
                 0.10877468 
                 0.25088354 
               
               
                 RPA3 
                 −0.04681671 
                 0.20367254 
                 0.25048925 
               
               
                 SIRPG 
                 −0.07999457 
                 0.17045821 
                 0.25045279 
               
               
                 CKS1B 
                 −0.17740757 
                 0.07276836 
                 0.25017593 
               
               
                 GNAQ 
                 0.160927429 
                 −0.08904675 
                 0.24997418 
               
               
                 KIAA0125 
                 −0.01354736 
                 0.23576654 
                 0.24931389 
               
               
                 S100A9 
                 0.215178714 
                 −0.03389743 
                 0.24907614 
               
               
                 SP140 
                 −0.047052 
                 0.20126089 
                 0.24831289 
               
               
                 CDKN2A 
                 −0.11248071 
                 0.13441996 
                 0.24690068 
               
               
                 HLA-DQB1 
                 0.046151929 
                 −0.19956661 
                 0.24571854 
               
               
                 BLK 
                 −0.00402536 
                 0.2414265 
                 0.24545186 
               
               
                 PKMYT1 
                 −0.10169271 
                 0.14326432 
                 0.24495704 
               
               
                 TRAPPC5 
                 0.121941143 
                 −0.12218889 
                 0.24413004 
               
               
                 LAT2 
                 0.145757571 
                 −0.09628264 
                 0.24204021 
               
               
                 TMEM176B 
                 0.069299714 
                 −0.17272923 
                 0.24202894 
               
               
                 ZYX 
                 0.168733429 
                 −0.07231025 
                 0.24104368 
               
               
                 IFI30 
                 0.144974 
                 −0.09603164 
                 0.24100564 
               
               
                 CTSH 
                 0.080306286 
                 −0.16066829 
                 0.24097457 
               
               
                 TNFSF13B 
                 0.105123786 
                 −0.1354275 
                 0.24055129 
               
               
                 RDH14 
                 −0.09425121 
                 0.14611864 
                 0.24036986 
               
               
                 GBP3 
                 −0.06468743 
                 0.17197089 
                 0.23665832 
               
               
                 CEP72 
                 −0.05021723 
                 0.18587307 
                 0.2360903 
               
               
                 ECM1 
                 0.243022929 
                 0.00739127 
                 0.23563166 
               
               
                 UMPS 
                 −0.02724029 
                 0.20625286 
                 0.23349314 
               
               
                 P2RX5 
                 0.043708071 
                 0.27604918 
                 0.23234111 
               
               
                 CTNNBIP1 
                 0.055695071 
                 −0.17643986 
                 0.23213493 
               
               
                 SMC4 
                 −0.0498615 
                 0.18205457 
                 0.23191607 
               
               
                 H2AFJ 
                 0.126527143 
                 −0.10458132 
                 0.23110846 
               
               
                 ITGAM 
                 0.178884429 
                 −0.05205179 
                 0.23093621 
               
               
                 RHOU 
                 0.091684 
                 −0.13749707 
                 0.22918107 
               
               
                 LRRC8A 
                 −0.15113114 
                 0.07662004 
                 0.22775118 
               
               
                 FAM105A 
                 0.051915571 
                 −0.17376321 
                 0.22567879 
               
               
                 FAM185A 
                 −0.1429 
                 0.0825775 
                 0.2254775 
               
               
                 RFC5 
                 −0.05649036 
                 0.16896686 
                 0.22545721 
               
               
                 TNFSF14 
                 0.0590265 
                 0.27745988 
                 0.21843338 
               
               
                 CX3CR1 
                 0.149541571 
                 0.36685596 
                 0.21731439 
               
               
                 PYCARD 
                 0.121423 
                 −0.09585457 
                 0.21727757 
               
               
                 TMEM154 
                 0.071312071 
                 −0.14592125 
                 0.21723332 
               
               
                 SGOL1 
                 0.177103671 
                 0.3921782 
                 0.21507453 
               
               
                 PARP9 
                 0.024120429 
                 0.23901993 
                 0.2148995 
               
               
                 CTSD 
                 0.130801929 
                 −0.08273682 
                 0.21353875 
               
               
                 DUSP22 
                 0.117107714 
                 −0.09505114 
                 0.21215886 
               
               
                 PTPN22 
                 −0.10790557 
                 0.10260764 
                 0.21051321 
               
               
                 AGPAT9 
                 0.151721714 
                 −0.05847029 
                 0.210192 
               
               
                 CLEC2D 
                 −0.12874 
                 0.080272 
                 0.209012 
               
               
                 CDK14 
                 0.174840186 
                 −0.03401502 
                 0.20885521 
               
               
                 KNTC1 
                 −0.03739463 
                 0.17103619 
                 0.20843081 
               
               
                 PHKB 
                 0.134422429 
                 −0.07178939 
                 0.20621182 
               
               
                 ESPL1 
                 −0.03134947 
                 0.17278559 
                 0.20413506 
               
               
                 HGSNAT 
                 0.083275071 
                 −0.12076807 
                 0.20404314 
               
               
                 ERI2 
                 0.238754243 
                 0.03538946 
                 0.20336479 
               
               
                 ENG 
                 0.069932214 
                 −0.13295171 
                 0.20288393 
               
               
                 POLA1 
                 −0.0924215 
                 0.10952729 
                 0.20194879 
               
               
                 AP1S2 
                 0.080564286 
                 −0.12097821 
                 0.2015425 
               
               
                 ADAM12 
                 0.063734771 
                 −0.13763672 
                 0.20137149 
               
               
                 FCGR1B 
                 0.321847429 
                 0.123407 
                 0.19844043 
               
               
                 TIPIN 
                 −0.073668 
                 0.12286243 
                 0.19653043 
               
               
                 NUSAP1 
                 −0.07885971 
                 0.11708601 
                 0.19594573 
               
               
                 TAF7 
                 −0.07773479 
                 0.11804689 
                 0.19578168 
               
               
                 GIMAP6 
                 0.000750143 
                 0.19616636 
                 0.19541621 
               
               
                 DNAJA3 
                 −0.08410257 
                 0.11076507 
                 0.19486764 
               
               
                 PAK1 
                 0.118213714 
                 −0.07653196 
                 0.19474568 
               
               
                 ADH5 
                 −0.07254686 
                 0.12209096 
                 0.19463782 
               
               
                 CD79A 
                 −0.04121671 
                 0.15056154 
                 0.19177825 
               
               
                 FCRL2 
                 0.158976771 
                 0.34783754 
                 0.18886076 
               
               
                 UPP1 
                 0.018764286 
                 −0.16593179 
                 0.18469607 
               
               
                 SIGLEC16 
                 0.136810429 
                 −0.04660093 
                 0.18341136 
               
               
                 LOC729313 
                 −0.12535821 
                 0.05648832 
                 0.18184654 
               
               
                 TCL1A 
                 0.149912429 
                 0.33119614 
                 0.18128371 
               
               
                 RBL2 
                 −0.05727793 
                 0.12376332 
                 0.18104125 
               
               
                 RAN 
                 −0.05334186 
                 0.12015604 
                 0.17349789 
               
               
                 ADRB2 
                 0.045381429 
                 0.21887268 
                 0.17349125 
               
               
                 SLC16A3 
                 0.166513429 
                 −0.00609168 
                 0.17260511 
               
               
                 MYO1F 
                 0.139853143 
                 −0.03228971 
                 0.17214286 
               
               
                 MYD88 
                 0.127095 
                 −0.04501275 
                 0.17210775 
               
               
                 SLC38A6 
                 0.090774214 
                 −0.07870346 
                 0.16947768 
               
               
                 POLA2 
                 −0.01999 
                 0.14915151 
                 0.16914151 
               
               
                 CYBB 
                 0.117763214 
                 −0.05079475 
                 0.16855796 
               
               
                 WDR92 
                 0.091065786 
                 0.25956021 
                 0.16849443 
               
               
                 SPIB 
                 −0.00710193 
                 0.16135964 
                 0.16846157 
               
               
                 NUP88 
                 −0.05180564 
                 0.11604057 
                 0.16784621 
               
               
                 SERPING1 
                 0.053220729 
                 −0.11385462 
                 0.16707535 
               
               
                 SPINT2 
                 0.075546857 
                 −0.09112346 
                 0.16667032 
               
               
                 MSH6 
                 −0.06019686 
                 0.1064115 
                 0.16660836 
               
               
                 HESX1 
                 0.287907157 
                 0.12251361 
                 0.16539355 
               
               
                 NCAPD3 
                 −0.06779679 
                 0.09737246 
                 0.16516925 
               
               
                 NCR1 
                 −0.1162164 
                 0.04860299 
                 0.16481939 
               
               
                 ATP8B4 
                 0.183999614 
                 0.02014505 
                 0.16385456 
               
               
                 SFXN3 
                 0.130900643 
                 −0.02609843 
                 0.15699907 
               
               
                 VRK1 
                 −0.09116879 
                 0.06370646 
                 0.15487525 
               
               
                 GPR82 
                 0.042014929 
                 0.1932354 
                 0.15122047 
               
               
                 NFE2 
                 0.313747714 
                 0.16882089 
                 0.14492682 
               
               
                 PUS7 
                 −0.04881071 
                 0.09542186 
                 0.14423257 
               
               
                 E2F2 
                 0.044565643 
                 0.18640229 
                 0.14183664 
               
               
                 TTF2 
                 0.050887143 
                 0.19187214 
                 0.140985 
               
               
                 STIL 
                 0.087016229 
                 0.22757289 
                 0.14055666 
               
               
                 SAMD9L 
                 0.035826214 
                 0.17281675 
                 0.13699054 
               
               
                 NDUFA8 
                 −0.02098714 
                 0.11569321 
                 0.13668036 
               
               
                 POP5 
                 −0.08173779 
                 0.05466404 
                 0.13640182 
               
               
                 CEP152 
                 0.105329543 
                 0.23961047 
                 0.13428093 
               
               
                 ANAPC10 
                 −0.04762379 
                 0.08661393 
                 0.13423771 
               
               
                 CD200 
                 0.2610974 
                 0.39524773 
                 0.13415033 
               
               
                 LRFN4 
                 0.0879955 
                 −0.04259586 
                 0.13059136 
               
               
                 CDK4 
                 −0.07956357 
                 0.05063243 
                 0.130196 
               
               
                 SMC3 
                 −0.05600471 
                 0.07299254 
                 0.12899725 
               
               
                 RARA 
                 0.000606714 
                 −0.12788275 
                 0.12848946 
               
               
                 CCR5 
                 0.238368786 
                 0.36464093 
                 0.12627214 
               
               
                 SOD2 
                 0.046425143 
                 −0.07868268 
                 0.12510782 
               
               
                 IFIT1 
                 0.165402214 
                 0.04272914 
                 0.12267307 
               
               
                 CKAP5 
                 0.069255357 
                 0.19171896 
                 0.12246361 
               
               
                 MX2 
                 0.111885786 
                 −0.00951561 
                 0.12140139 
               
               
                 ARNTL2 
                 0.217624257 
                 0.09715989 
                 0.12046437 
               
               
                 CCNF 
                 0.137269371 
                 0.25590687 
                 0.1186375 
               
               
                 CRTAM 
                 0.051424714 
                 0.16918629 
                 0.11776157 
               
               
                 SMARCAL1 
                 −0.02277143 
                 0.09328157 
                 0.116053 
               
               
                 PTGIR 
                 0.084466786 
                 −0.02833125 
                 0.11279804 
               
               
                 MICB 
                 −0.0206175 
                 0.08935289 
                 0.10997039 
               
               
                 CASP7 
                 −0.01341543 
                 0.09496736 
                 0.10838279 
               
               
                 ATR 
                 0.014273714 
                 0.12143018 
                 0.10715646 
               
               
                 TNFAIP6 
                 0.250598143 
                 0.14354166 
                 0.10705648 
               
               
                 CXCR5 
                 −0.04794986 
                 0.05755599 
                 0.10550584 
               
               
                 EIF2B3 
                 −0.05847921 
                 0.04699932 
                 0.10547854 
               
               
                 TOPBP1 
                 0.026353643 
                 0.13146668 
                 0.10511304 
               
               
                 JMJD4 
                 0.000444143 
                 0.10119504 
                 0.10075089 
               
               
                 PLK1 
                 0.4368879 
                 0.34197855 
                 0.09490935 
               
               
                 CSF2RB 
                 −0.01162973 
                 −0.10319299 
                 0.09156326 
               
               
                 AFF3 
                 0.078227586 
                 −0.0107089 
                 0.08893649 
               
               
                 HIBCH 
                 0.047619643 
                 0.13565057 
                 0.08803093 
               
               
                 SKP2 
                 0.129403057 
                 0.0431865 
                 0.08621656 
               
               
                 MYO7B 
                 0.2198644 
                 0.13441515 
                 0.08544925 
               
               
                 CEBPE 
                 0.125281429 
                 0.04241404 
                 0.08286739 
               
               
                 RALGPS2 
                 0.251390957 
                 0.16886784 
                 0.08252311 
               
               
                 MCM5 
                 −0.00196914 
                 0.08003532 
                 0.08200446 
               
               
                 IFIH1 
                 0.13203 
                 0.21265864 
                 0.08062864 
               
               
                 PSEN2 
                 0.025384786 
                 −0.05427521 
                 0.07966 
               
               
                 SSBP1 
                 −0.02960171 
                 0.04982696 
                 0.07942868 
               
               
                 CHEK2 
                 −0.04968586 
                 0.02740482 
                 0.07709068 
               
               
                 TMPO 
                 −0.008721 
                 0.06823154 
                 0.07695254 
               
               
                 CDC23 
                 0.067964857 
                 0.14406679 
                 0.07610193 
               
               
                 TCHP 
                 0.135090829 
                 0.20927789 
                 0.07418706 
               
               
                 VPREB3 
                 0.289311429 
                 0.36304514 
                 0.07373371 
               
               
                 CD72 
                 0.013276714 
                 −0.05565957 
                 0.06893629 
               
               
                 NPL 
                 −0.06360071 
                 0.004466 
                 0.06806671 
               
               
                 DTYMK 
                 0.008803929 
                 0.07686164 
                 0.06805771 
               
               
                 TRAF3IP3 
                 0.081071571 
                 0.14877989 
                 0.06770832 
               
               
                 CORO1A 
                 −0.00652207 
                 0.05883071 
                 0.06535279 
               
               
                 GPR137B 
                 0.036305643 
                 −0.02776493 
                 0.06407057 
               
               
                 POLD3 
                 0.146014357 
                 0.08214118 
                 0.06387318 
               
               
                 FCRLA 
                 0.182630857 
                 0.24622307 
                 0.06359221 
               
               
                 ERCC6L 
                 0.302153757 
                 0.24002681 
                 0.06212694 
               
               
                 KIF23 
                 0.091604929 
                 0.03388473 
                 0.0577202 
               
               
                 HLA-DOB 
                 0.097279429 
                 0.15183752 
                 0.05455809 
               
               
                 ALG8 
                 −0.02051879 
                 0.03389046 
                 0.05440925 
               
               
                 PSMA3 
                 −0.00942914 
                 0.04492389 
                 0.05435304 
               
               
                 CENPN 
                 −0.15527079 
                 −0.10123914 
                 0.05403164 
               
               
                 ACADM 
                 0.033363857 
                 0.08598743 
                 0.05262357 
               
               
                 RSAD2 
                 0.133737286 
                 0.1858205 
                 0.05208321 
               
               
                 TSPAN13 
                 −0.05419761 
                 −0.00318473 
                 0.05101289 
               
               
                 BRCA1 
                 0.1411805 
                 0.19119731 
                 0.05001681 
               
               
                 ABCC3 
                 −0.07408826 
                 −0.12342445 
                 0.04933619 
               
               
                 HLA-DOA 
                 −0.06191443 
                 −0.014744 
                 0.04717043 
               
               
                 VSIG10 
                 −0.03624206 
                 −0.07780171 
                 0.04155966 
               
               
                 WHAMM 
                 −0.05727821 
                 −0.01795696 
                 0.03932125 
               
               
                 CEACAM1 
                 0.031373857 
                 −0.00674968 
                 0.03812354 
               
               
                 TFDP1 
                 0.030716571 
                 0.06752414 
                 0.03680757 
               
               
                 KIF20B 
                 0.010597143 
                 0.04736749 
                 0.03677035 
               
               
                 FAM129C 
                 0.110318657 
                 0.14503139 
                 0.03471274 
               
               
                 MACROD2 
                 0.0716402 
                 0.10401612 
                 0.03237592 
               
               
                 PPIL4 
                 0.002354786 
                 0.03106729 
                 0.0287125 
               
               
                 CD24 
                 0.428375214 
                 0.40792088 
                 0.02045434 
               
               
                 FAM129A 
                 0.113804357 
                 0.09346804 
                 0.02033632 
               
               
                 ZNF467 
                 −0.01551657 
                 0.0041065 
                 0.01962307 
               
               
                 ADAM28 
                 −0.0506592 
                 −0.07003481 
                 0.01937561 
               
               
                 SAMHD1 
                 −0.0260325 
                 −0.01032382 
                 0.01570868 
               
               
                 ECT2 
                 0.099594771 
                 0.08800196 
                 0.01159281 
               
               
                 KMO 
                 0.078771714 
                 0.09002297 
                 0.01125126 
               
               
                 ASF1B 
                 0.069384957 
                 0.0609988 
                 0.00838616 
               
               
                 PSTPIP1 
                 0.077608714 
                 0.07232871 
                 0.00528 
               
               
                 RMI1 
                 0.229338371 
                 0.23179671 
                 0.00245834 
               
               
                   
               
            
           
         
       
     
     Study 2 
     The multi-antigenic CV9104 as described in WO2015024664 is an mRNA-based immunotherapeutic and a further development of CV9103 (Kübler H, et al. “Self-adjuvanted mRNA vaccination in advanced prostate cancer patients: a first-in-man phase I/IIa study.” J Immunother Cancer. 2015 Jun. 16; 3:26.). It encodes for six cancer antigens associated with prostate cancer: Muc-1, PSA, PSCA, PSMA, STEAP-1 and PAP. A total of 46 pre-operative prostate cancer patients were divided into three groups. Cohort A received up to four intradermal immunizations of 160 μg RNA for each antigen using the needle-free injection device Tropis. Patients in cohort B received 320 μg of RNA for each antigen by intradermal syringe-needle injection whereas cohort C patient remained untreated. Venous blood samples for gene expression profiling were taken at week 6 (1-2 weeks after the fourth mRNA treatment) and 8 weeks after prostatectomy. Blood was harvested into PAXgene® RNA tubes, frozen and stored at −80° C. until further processing. 14 subjects in cohort A, and 16 subjects each in cohorts B and C were evaluable. 
     Frozen PAXgene® samples were transferred to IMGM for isolation of RNA and microarray analysis. Blood samples were thawed and incubated at room temperature to ensure complete lysis of leukocytes before RNA isolation. Total RNA including miRNAs were isolated using the PAXgene® Blood miRNA Kit (Qiagen) according to the manufacturer&#39;s instructions including on-column DNAse digestion. Total RNA was eluted in 80 μl buffer. 
     RNA quantity and quality were assessed using the NanoDrop NK-1000 spectral photometer (peqlab) and integrity was analyzed on the 2100 Bioanalyzer using RNA 6000 Nano LabChip Kits (Agilent Technologies). Cyanine-3-labelling of cRNA and hybridization using the Agilent SurePrint G3 Human Gene Expression 8×60K v2 Microarray platform was performed by IMGM according to manufacturer&#39;s manuals (Agilent Technologies). Raw data was processed using following software tools: Feature Extraction 10.7.3.1 and GeneSpring GX 13.1.1 (both Agilent Techlogies). Quantile normalization was applied to the data set and log 2-transformed and filtered for probes detectable in at least one sample. 
     To determine the transcriptional changes in prostate cancer patients after CV9104 treatment we performed gene set enrichment analysis (GSEA) using blood transcriptional modules (BTMs) as gene sets (Li S et al. “Molecular signatures of antibody responses derived from a systems biology study of five human vaccines” Nat Immunol. 2014 February; 15(2):195-204). Gene lists were ranked based on paired t-test P values comparing the week 6 with baseline samples for each of the three patient cohorts. In addition, we also combined arms A and B (treated cohorts) to increase the statistical power and sensitivity of the GSEA approach. The GSEA results show that modules consistent with a T and NK cell profile were up-regulated at week 6 in subjects receiving CV9104 treatment but not in the control arm C ( FIG. 1 ). 
     Gene Set Enrichment Analyses were performed comparing week 6 to week 1, and week 8 to week 1, for each of the two vaccine arms, and the control arm, individually, using the Blood Transcriptome Module gene sets as probes. 
     For each contrast, the 10 Blood Transcriptome Modules having the highest enrichment scores were selected, and the leading edge genes (the subset of genes that contribute most to the enrichment score) from each module were selected. 
     For this combined list of 725 unique leading edge genes, mean expression values for each experimental arm and time point were calculated. For transcripts that were represented by more than one probe in the microarray, the probe expression values of the probe having the highest mean expression in all samples was used. 
     Log 2 fold changes (differences in log 2 expression values) between week 6 and week 1, for each vaccine arm and the control arm were calculated. 
     To identify the genes that are regulated from week 1 to week 6 most differently in the vaccine recipients and the control group, the difference between the combined vaccine arm log 2 fold changes and the control arm log 2 fold changes was calculated (table 17). In table 17 the genes based on the absolute value of this difference, such that the genes at the top of the list are the most differently regulated between vaccine recipients and the control arm, whether those genes are up regulated to a greater extent over time, in vaccine recipients than in the control group, or down regulated to a greater extent over time, in vaccine recipients than in the control group. 
     Overlapping Marker Genes of Study 1 and Study 2 
     Subsequently a subset of 402 of the 725 prostate cancer vaccine leading edge genes was selected, that were also found in the nsclc set of select genes (table 18). 
     This subset of select genes identified from analyses of both nsclc and prostate vaccine trials was ranked in the identical way as the total list of prostate vaccine leading edge genes, such that in table 18 the genes at the top of the list are the most differently regulated between prostate cancer vaccine recipients and the control arm, whether those genes are up regulated to a greater extent over time, in vaccine recipients than in the control group, or down regulated to a greater extent over time, in vaccine recipients than in the control group. 
     
       
         
           
               
             
               
                 TABLE 17 
               
             
            
               
                   
               
               
                 difference between the combined vaccine arm log2 fold changes and the control 
               
               
                 arm log2 fold changes; treatment with CV9104 (full name and accession number 
               
               
                 as set out in Table 6). 
               
            
           
           
               
               
               
               
               
               
            
               
                   
                   
                   
                   
                 Differential 
                   
               
               
                   
                   
                   
                   
                 Expression 
                 Absolute value 
               
               
                 Gene 
                   
                   
                   
                 (armA + armB) −  
                 ((armA + armB) − 
               
               
                 Symbol 
                 ArmA (A6v1) 
                 ArmB (B6v1) 
                 ArmC (C6v1)  
                 armC 
                 armC) 
               
               
                   
               
            
           
           
               
               
               
               
               
               
            
               
                 COX7B 
                 −0.606408264  
                 −0.502341075 
                 0.564692875 
                 −1.673442214  
                 1.673442214 
               
               
                 LY96 
                 −0.665603021  
                 −0.467714725 
                 0.450183881 
                 −1.583501628  
                 1.583501628 
               
               
                 FIGNL1 
                 −0.720155553  
                 −0.143864925 
                 0.655112416 
                 −1.519132894  
                 1.519132894 
               
               
                 FOSL1 
                 0.464989686 
                 0.719168288 
                 −0.332139931 
                 1.516297904  
                 1.516297904 
               
               
                 S100A8 
                 −0.635815857  
                 −0.330874531 
                 0.521352125 
                 −1.488042513  
                 1.488042513 
               
               
                 GFRA3 
                 0.44628215 
                 0.135059706 
                 −0.759570281 
                 1.340912138  
                 1.340912138 
               
               
                 REEP1 
                 0.665988507 
                 −0.0688409 
                 −0.742842819 
                 1.339990426  
                 1.339990426 
               
               
                 SUV39H2 
                 −0.106513621  
                 −0.968136388 
                 0.264257213 
                 −1.338907221  
                 1.338907221 
               
               
                 ZFYVE16 
                 −0.390657514  
                 −0.330864481 
                 0.523502294 
                 −1.245024289  
                 1.245024289 
               
               
                 NDUFA4 
                 −0.37000875  
                 −0.313184906 
                 0.552544125 
                 −1.235737781  
                 1.235737781 
               
               
                 FOXN1 
                 0.558560786  
                 −0.034936269 
                 −0.643069656 
                 1.166694173  
                 1.166694173 
               
               
                 KIR2DL4 
                 0.443792343 
                 0.044371956 
                 −0.643219638 
                 1.131383937  
                 1.131383937 
               
               
                 GOLT1B 
                 −0.282865464  
                 −0.210463281 
                 0.6321674 
                 −1.125496146  
                 1.125496146 
               
               
                 NLRC3 
                 0.476656929 
                 0.03283075 
                 −0.5611875 
                 1.070675179  
                 1.070675179 
               
               
                 ACTR6 
                 −0.310453271  
                 −0.124797413 
                 0.624728813 
                 −1.059979496  
                 1.059979496 
               
               
                 PLEKHF2 
                 −0.329232657  
                 −0.282916569 
                 0.435252575 
                 −1.047401801  
                 1.047401801 
               
               
                 TFEC 
                 −0.318235514  
                 −0.242671238 
                 0.483973406 
                 −1.044880158  
                 1.044880158 
               
               
                 LGALS2 
                 −0.385623  
                 −0.130118344 
                 0.527391187 
                 −1.043132531  
                 1.043132531 
               
               
                 MSH6 
                 0.261864307 
                 0.025887787 
                 −0.732941019 
                 1.020693113  
                 1.020693113 
               
               
                 TARP 
                 0.378694321 
                 0.076621125 
                 −0.561206219 
                 1.016521665  
                 1.016521665 
               
               
                 MND1 
                 −0.404708544  
                 −0.187105296 
                 0.391868744 
                 −0.983682584  
                 0.983682584 
               
               
                 S100A12 
                 −0.41744775 
                 −0.10775675 
                 0.439791875 
                 −0.964996375  
                 0.964996375 
               
               
                 AGL 
                 0.001249657  
                 −0.244289288 
                 0.714159275 
                 −0.957198905  
                 0.957198905 
               
               
                 NUPL2 
                 0.145023043 
                 0.174428356 
                 −0.636780513 
                 0.956231912  
                 0.956231912 
               
               
                 PKMYT1 
                 0.142765721 
                 0.224433575 
                 −0.588215069 
                 0.955414365  
                 0.955414365 
               
               
                 PTAFR 
                 0.379653786 
                 0.146566969 
                 −0.422391625 
                 0.948612379  
                 0.948612379 
               
               
                 VSTM1 
                 −0.193381857  
                 −0.090299613 
                 0.653519906 
                 −0.937201376  
                 0.937201376 
               
               
                 SAMHD1 
                 0.131552171  
                 −0.126445206 
                 −0.929604906 
                 0.934711871  
                 0.934711871 
               
               
                 ASPA 
                 0.5491103  
                 −0.275201025 
                 −0.646884206 
                 0.920793481  
                 0.920793481 
               
               
                 PPP1R12A 
                 −0.234674457  
                 −0.430710625 
                 0.246988487 
                 −0.91237357 
                 0.91237357 
               
               
                 UQCRQ 
                 −0.310938071  
                 −0.136146531 
                 0.456713938 
                 −0.90379854 
                 0.90379854 
               
               
                 OSMR 
                 −0.321796071  
                 −0.129218388 
                 0.450057575 
                 −0.901072034  
                 0.901072034 
               
               
                 SP3 
                 −0.318489871  
                 −0.188125025 
                 0.393770081 
                 −0.900384978  
                 0.900384978 
               
               
                 JPH2 
                 0.368767479 
                 0.063154694 
                 −0.46770085 
                 0.899623022  
                 0.899623022 
               
               
                 APCDD1 
                 −0.273886843  
                 −0.087978469 
                 0.529121788 
                 −0.890987099  
                 0.890987099 
               
               
                 ABCG2 
                 0.20306705 
                 0.194013125 
                 −0.48904895 
                 0.886129125  
                 0.886129125 
               
               
                 TLR7 
                 −0.147615186  
                 −0.321601119 
                 0.406793494 
                 −0.876009798  
                 0.876009798 
               
               
                 ATP5C1 
                 −0.292455107  
                 −0.163626494 
                 0.418519875 
                 −0.874601476  
                 0.874601476 
               
               
                 GINS1 
                 −0.113533457  
                 −0.166327694 
                 0.59447155 
                 −0.874332701  
                 0.874332701 
               
               
                 CKS2 
                 −0.289032207  
                 −0.149659806 
                 0.429285544 
                 −0.867977557  
                 0.867977557 
               
               
                 NOC3L 
                 −0.18972425  
                 −0.159537525 
                 0.515942431 
                 −0.865204206  
                 0.865204206 
               
               
                 DEK 
                 −0.1939215  
                 −0.206601375 
                 0.464482169 
                 −0.865005044  
                 0.865005044 
               
               
                 HNMT 
                 −0.295274607  
                 −0.333069056 
                 0.23338665 
                 −0.861730313  
                 0.861730313 
               
               
                 MS4A4A 
                 −0.169447907  
                 −0.078548325 
                 0.612627775 
                 −0.860624007  
                 0.860624007 
               
               
                 TMEM55A 
                 −0.253421071  
                 −0.191611125 
                 0.41530585 
                 −0.860338046  
                 0.860338046 
               
               
                 TMX1 
                 −0.122000464  
                 −0.269148656 
                 0.468426 
                 −0.859575121  
                 0.859575121 
               
               
                 USP1 
                 −0.251525429  
                 −0.143212106 
                 0.460652213 
                 −0.855389747  
                 0.855389747 
               
               
                 CCDC80 
                 0.506134793  
                 −0.258483075 
                 −0.604203344 
                 0.851855062  
                 0.851855062 
               
               
                 PCNP 
                 −0.236255293 
                 −0.19787625 
                 0.412827844 
                 −0.846959387  
                 0.846959387 
               
               
                 SHCBP1 
                 0.042455016  
                 −0.179903435 
                 0.709211203 
                 −0.846659622  
                 0.846659622 
               
               
                 PANK3 
                 −0.165479279  
                 −0.210394325 
                 0.466273875 
                 −0.842147479  
                 0.842147479 
               
               
                 PAQR3 
                 0.152645179  
                 −0.272095394 
                 0.720825238 
                 −0.840275453  
                 0.840275453 
               
               
                 RNF138 
                 −0.192648857  
                 −0.135220038 
                 0.5105123 
                 −0.838381195  
                 0.838381195 
               
               
                 CD302 
                 −0.218855893  
                 −0.262976719 
                 0.352909463 
                 −0.834742074  
                 0.834742074 
               
               
                 NUP35 
                 −0.173067586  
                 −0.047440819 
                 0.608632838 
                 −0.829141242  
                 0.829141242 
               
               
                 IMPA1 
                 −0.197582071 
                 −0.142449 
                 0.484175444 
                 −0.824206515  
                 0.824206515 
               
               
                 MS4A7 
                 −0.134199121  
                 −0.178824338 
                 0.50987265 
                 −0.822896109  
                 0.822896109 
               
               
                 SGMS1 
                 −0.136948443  
                 −0.118781288 
                 0.559130738 
                 −0.814860468  
                 0.814860468 
               
               
                 GALNT7 
                 −0.135803271  
                 −0.206088844 
                 0.462692475 
                 −0.80458459 
                 0.80458459 
               
               
                 CA14 
                 0.260723136 
                 −0.096292 
                 −0.633484169 
                 0.797915304  
                 0.797915304 
               
               
                 RHOU 
                 −0.231164307  
                 −0.186997156 
                 0.375615037 
                 −0.793776501  
                 0.793776501 
               
               
                 PHTF2 
                 −0.190424793 
                 −0.1227072 
                 0.475077756 
                 −0.788209749  
                 0.788209749 
               
               
                 S100A9 
                 −0.320247  
                 −0.153805438 
                 0.307592 
                 −0.781644438  
                 0.781644438 
               
               
                 FAM198B 
                 −0.145417936  
                 −0.139593244 
                 0.494443025 
                 −0.779454204  
                 0.779454204 
               
               
                 ST3GAL6 
                 −0.237888643  
                 −0.076946094 
                 0.457763138 
                 −0.772597874  
                 0.772597874 
               
               
                 CLK4 
                 −0.141728729  
                 −0.188919619 
                 0.441717688 
                 −0.772366035  
                 0.772366035 
               
               
                 CLEC12A 
                 −0.195821829  
                 −0.175847275 
                 0.397432788 
                 −0.769101891  
                 0.769101891 
               
               
                 GCA 
                 −0.207991036  
                 −0.145952313 
                 0.408222094 
                 −0.762165442  
                 0.762165442 
               
               
                 VNN2 
                 −0.330711179  
                 −0.080868031 
                 0.348413594 
                 −0.759992804  
                 0.759992804 
               
               
                 C1GALT1C1 
                 −0.217019586  
                 −0.126876731 
                 0.414085394 
                 −0.757981711  
                 0.757981711 
               
               
                 DUSP6 
                 −0.247050464  
                 −0.126289281 
                 0.379623406 
                 −0.752963152  
                 0.752963152 
               
               
                 TNFAIP8 
                 −0.181705214  
                 −0.096119594 
                 0.468258469 
                 −0.746083277  
                 0.746083277 
               
               
                 TLR4 
                 −0.240381679  
                 −0.172451125 
                 0.331507775 
                 −0.744340579  
                 0.744340579 
               
               
                 FBLN1 
                 0.1964213 
                 0.051661288 
                 −0.49446335 
                 0.742545938  
                 0.742545938 
               
               
                 LRRK2 
                 −0.155146307 
                 −0.16335285 
                 0.423976512 
                 −0.74247567 
                 0.74247567 
               
               
                 SLC46A2 
                 −0.282207129 
                 −0.14557735 
                 0.312664669 
                 −0.740449147  
                 0.740449147 
               
               
                 KIAA1468 
                 −0.1790219  
                 −0.069215494 
                 0.49012375 
                 −0.738361144  
                 0.738361144 
               
               
                 AIF1 
                 −0.260561036 
                 0.026826062 
                 0.500316375 
                 −0.734051348  
                 0.734051348 
               
               
                 HK3 
                 −0.234775807  
                 −0.097156719 
                 0.401606381 
                 −0.733538907  
                 0.733538907 
               
               
                 SFRP4 
                 −0.026588329  
                 −0.011432458 
                 0.692197892 
                 −0.730218679  
                 0.730218679 
               
               
                 ARFIP1 
                 −0.177901243  
                 −0.093895375 
                 0.456699719 
                 −0.728496337  
                 0.728496337 
               
               
                 COX6C 
                 −0.219954821 
                 −0.05217725 
                 0.449419019 
                 −0.72155109 
                 0.72155109 
               
               
                 DMD 
                 0.217219014 
                 0.187473034 
                 −0.314012238 
                 0.718704286  
                 0.718704286 
               
               
                 KYNU 
                 −0.212530664  
                 −0.096688537 
                 0.409357369 
                 −0.718576571  
                 0.718576571 
               
               
                 PIK3C2A 
                 −0.163213964 
                 −0.11146845 
                 0.4358585 
                 −0.710540914  
                 0.710540914 
               
               
                 NDUFB1 
                 −0.253689429  
                 −0.107063188 
                 0.347131438 
                 −0.707884054  
                 0.707884054 
               
               
                 VNN1 
                 −0.251333021  
                 −0.035195975 
                 0.420730019 
                 −0.707259015  
                 0.707259015 
               
               
                 MBNL1 
                 −0.15993675  
                 −0.120846844 
                 0.424152594 
                 −0.704936188  
                 0.704936188 
               
               
                 ABCA1 
                 −0.094451293  
                 −0.182310388 
                 0.427960444 
                 −0.704722124  
                 0.704722124 
               
               
                 PID1 
                 −0.2533088  
                 −0.008741875 
                 0.435348662 
                 −0.697399337  
                 0.697399337 
               
               
                 SRP9 
                 −0.242651436  
                 −0.045872794 
                 0.405947088 
                 −0.694471317  
                 0.694471317 
               
               
                 MAD2L1 
                 0.115332107  
                 −0.108857088 
                 0.699806038 
                 −0.693331018  
                 0.693331018 
               
               
                 GLIPR1 
                 −0.2337439  
                 −0.054035794 
                 0.403475625 
                 −0.691255319  
                 0.691255319 
               
               
                 NUP107 
                 −0.134396293  
                 −0.066036206 
                 0.488358206 
                 −0.688790705  
                 0.688790705 
               
               
                 GZMK 
                 −0.174657143  
                 −0.005958313 
                 0.505133219 
                 −0.685748674  
                 0.685748674 
               
               
                 STAG2 
                 −0.239123807  
                 −0.229557394 
                 0.215309431 
                 −0.683990632  
                 0.683990632 
               
               
                 NDUFB3 
                 −0.343863679  
                 −0.035564125 
                 0.302523406 
                 −0.68195121 
                 0.68195121 
               
               
                 CYP1B1 
                 −0.265192214  
                 −0.256149313 
                 0.157784531 
                 −0.679126058  
                 0.679126058 
               
               
                 MYBL2 
                 0.270149364 
                 0.164981162 
                 −0.243983306 
                 0.679113833  
                 0.679113833 
               
               
                 KLF1 
                 0.363923679 
                 0.009731187 
                 −0.305278563 
                 0.678933429  
                 0.678933429 
               
               
                 IFI30 
                 −0.188249714  
                 −0.067891938 
                 0.422337406 
                 −0.678479058  
                 0.678479058 
               
               
                 ICOS 
                 −0.195708336 
                 −0.1017867 
                 0.379751075 
                 −0.677246111  
                 0.677246111 
               
               
                 TNFSF11 
                 0.142212907 
                 0.4536486 
                 −0.079978531 
                 0.675840038  
                 0.675840038 
               
               
                 NDUFB2 
                 −0.171665107  
                 −0.084994719 
                 0.418124344 
                 −0.67478417 
                 0.67478417 
               
               
                 TGM2 
                 0.535738693 
                 0.164614425 
                 0.026084025 
                 0.674269093  
                 0.674269093 
               
               
                 CUL5 
                 −0.104067314  
                 −0.157484131 
                 0.408924988 
                 −0.670476433  
                 0.670476433 
               
               
                 CD28 
                 −0.208329314  
                 −0.103989013 
                 0.357281481 
                 −0.669599808  
                 0.669599808 
               
               
                 SGK1 
                 −0.211915821  
                 −0.061046906 
                 0.394467688 
                 −0.667430415  
                 0.667430415 
               
               
                 PLA2G7 
                 −0.180527121  
                 −0.099741525 
                 0.381482469 
                 −0.661751115  
                 0.661751115 
               
               
                 RMI1 
                 −0.199934986 
                 −0.04289555 
                 0.413915156 
                 −0.656745692  
                 0.656745692 
               
               
                 GPSM2 
                 −0.309434029 
                 0.137679244 
                 0.481535488 
                 −0.653290272  
                 0.653290272 
               
               
                 ZDHHC17 
                 −0.0802091  
                 −0.095862544 
                 0.471754831 
                 −0.647826475  
                 0.647826475 
               
               
                 CCR2 
                 −0.152288  
                 −0.171936281 
                 0.319978406 
                 −0.644202687  
                 0.644202687 
               
               
                 FCN1 
                 −0.153257  
                 −0.084273781 
                 0.405351719 
                 −0.6428825 
                 0.6428825 
               
               
                 ZWINT 
                 −0.07826045 
                 −0.311652 
                 0.25231555 
                 −0.642228 
                 0.642228 
               
               
                 AMICA1 
                 −0.193698571  
                 −0.108480063 
                 0.336439188 
                 −0.638617821  
                 0.638617821 
               
               
                 CLEC7A 
                 −0.342173264  
                 −0.138714325 
                 0.15760535 
                 −0.638492939  
                 0.638492939 
               
               
                 ERBB2IP 
                 −0.08476425 
                 −0.0988105 
                 0.4519725 
                 −0.63554725 
                 0.63554725 
               
               
                 MSH2 
                 −0.07557825  
                 −0.037042687 
                 0.521162963 
                 −0.6337839 
                 0.6337839 
               
               
                 RIN2 
                 −0.200246857  
                 −0.019231919 
                 0.412999538 
                 −0.632478313  
                 0.632478313 
               
               
                 MORC3 
                 −0.139277757  
                 −0.150871294 
                 0.339561112 
                 −0.629710163  
                 0.629710163 
               
               
                 MFSD1 
                 −0.141775179  
                 −0.013945156 
                 0.467410156 
                 −0.623130491  
                 0.623130491 
               
               
                 KCNJ2 
                 −0.114933607 
                 −0.185105 
                 0.322908125 
                 −0.622946732  
                 0.622946732 
               
               
                 LMNB1 
                 −0.200508029  
                 −0.200736762 
                 0.220277363 
                 −0.621522154  
                 0.621522154 
               
               
                 CCT2 
                 −0.125265893 
                 −0.03601025 
                 0.457937938 
                 −0.61921408 
                 0.61921408 
               
               
                 IFNG 
                 −0.149614136  
                 −0.045758312 
                 0.4236398 
                 −0.619012248  
                 0.619012248 
               
               
                 EEF1G 
                 −0.114996857 
                 −0.112516 
                 0.390455125 
                 −0.617967982  
                 0.617967982 
               
               
                 CSTA 
                 −0.44455025 
                 0.042660713 
                 0.212461756 
                 −0.614351294  
                 0.614351294 
               
               
                 MYBL1 
                 −0.114428693  
                 −0.076983169 
                 0.422538056 
                 −0.613949918  
                 0.613949918 
               
               
                 MNDA 
                 −0.026950107 
                 0.015162656 
                 0.600877938 
                 −0.612665388  
                 0.612665388 
               
               
                 PAQR9 
                 0.64432315 
                 −0.0259158 
                 0.006397187 
                 0.612010163  
                 0.612010163 
               
               
                 ZBTB11 
                 −0.167650657  
                 −0.232606775 
                 0.211601269 
                 −0.611858701  
                 0.611858701 
               
               
                 RBP7 
                 −0.21202525  
                 −0.083316812 
                 0.315361469 
                 −0.610703531  
                 0.610703531 
               
               
                 ZNF700 
                 −0.135721093 
                 0.039511994 
                 0.513713188 
                 −0.609922287  
                 0.609922287 
               
               
                 BST1 
                 −0.140568821  
                 −0.056846906 
                 0.4086275 
                 −0.606043228  
                 0.606043228 
               
               
                 ATP5O 
                 −0.170172643 
                 0.013251563 
                 0.446425125 
                 −0.603346205  
                 0.603346205 
               
               
                 ATAD2 
                 −0.182130779  
                 −0.024369794 
                 0.396607131 
                 −0.603107704  
                 0.603107704 
               
               
                 DLGAP5 
                 −0.426307121 
                 0.209794425 
                 0.383806556 
                 −0.600319253  
                 0.600319253 
               
               
                 NOD2 
                 −0.102332229 
                 −0.045682 
                 0.451739 
                 −0.599753229  
                 0.599753229 
               
               
                 LILRA3 
                 −0.15567315  
                 −0.014400075 
                 0.423342813 
                 −0.593416037  
                 0.593416037 
               
               
                 CLEC4A 
                 −0.173481786  
                 −0.021148656 
                 0.396113531 
                 −0.590743973  
                 0.590743973 
               
               
                 TNFSF13B 
                 −0.169967071  
                 −0.160481406 
                 0.258797906 
                 −0.589246384  
                 0.589246384 
               
               
                 CSF2RA 
                 −0.132171093 
                 −0.0562483 
                 0.400639056 
                 −0.589058449  
                 0.589058449 
               
               
                 BRI3 
                 −0.103865857  
                 −0.058436312 
                 0.425253469 
                 −0.587555638  
                 0.587555638 
               
               
                 RNF6 
                 −0.109517936  
                 −0.087212163 
                 0.390214419 
                 −0.586944517 
                 0.586944517 
               
               
                 PTTG3P 
                 0.00596525  
                 −0.251395406 
                 0.338894319 
                 −0.584324475  
                 0.584324475 
               
               
                 HSPD1 
                 −0.147717536  
                 −0.001791687 
                 0.434780906 
                 −0.584290129  
                 0.584290129 
               
               
                 GTF2H1 
                 −0.187885957 
                 0.078702969 
                 0.472787963 
                 −0.581970951  
                 0.581970951 
               
               
                 LMO2 
                 −0.169893857  
                 −0.058435719 
                 0.351577969 
                 −0.579907545  
                 0.579907545 
               
               
                 KIAA0101 
                 −0.041091293 
                 −0.16191575 
                 0.375725275 
                 −0.578732318  
                 0.578732318 
               
               
                 RFC5 
                 −0.098490279  
                 −0.093795681 
                 0.385063719 
                 −0.577349679  
                 0.577349679 
               
               
                 RAD50 
                 −0.140694379 
                 0.0111879 
                 0.447346706 
                 −0.576853185  
                 0.576853185 
               
               
                 FEN1 
                 0.084685657  
                 −0.025203925 
                 0.636262238 
                 −0.576780505  
                 0.576780505 
               
               
                 NUP54 
                 −0.11629505 
                 0.019289113 
                 0.479259756 
                 −0.576265694  
                 0.576265694 
               
               
                 NDUFS4 
                 −0.264559636 
                 0.068452419 
                 0.377871181 
                 −0.573978398  
                 0.573978398 
               
               
                 PTPN22 
                 −0.2530378  
                 −0.011789731 
                 0.308368238 
                 −0.573195769  
                 0.573195769 
               
               
                 CDKN3 
                 −0.444022514  
                 −0.092208262 
                 0.035993937 
                 −0.572224714  
                 0.572224714 
               
               
                 MAGEA12 
                 0.289114343 
                 0.171728456 
                 −0.109750269 
                 0.570593068  
                 0.570593068 
               
               
                 VPS4B 
                 −0.048524464 
                 −0.153786 
                 0.364946938 
                 −0.567257402  
                 0.567257402 
               
               
                 EIF3E 
                 −0.072937214 
                 0.03722425 
                 0.529808094 
                 −0.565521058  
                 0.565521058 
               
               
                 HLA-DPB1 
                 −0.070855679  
                 −0.032144094 
                 0.460644375 
                 −0.563644147  
                 0.563644147 
               
               
                 NCAPG 
                 0.197792818 
                 0.125748924 
                 −0.239994872 
                 0.563536614  
                 0.563536614 
               
               
                 CREBZF 
                 −0.096819921 
                 0.0781624 
                 0.544589869 
                 −0.56324739 
                 0.56324739 
               
               
                 ITSN2 
                 0.132176686  
                 −0.003463494 
                 −0.434241769 
                 0.562954961  
                 0.562954961 
               
               
                 QPCT 
                 −0.154081286 
                 0.022183281 
                 0.42981575 
                 −0.561713754  
                 0.561713754 
               
               
                 BZW1 
                 −0.136054786  
                 −0.134614969 
                 0.288626881 
                 −0.559296636  
                 0.559296636 
               
               
                 NDC80 
                 −0.188322236 
                 0.161280275 
                 0.530858019 
                 −0.557899979  
                 0.557899979 
               
               
                 ZFAND6 
                 −0.163411964  
                 −0.011106687 
                 0.381657531 
                 −0.556176183  
                 0.556176183 
               
               
                 KIR2DS2 
                 0.164195243 
                 0.152554619 
                 −0.23917585 
                 0.555925712  
                 0.555925712 
               
               
                 CCNC 
                 −0.106666914  
                 −0.121181388 
                 0.326487469 
                 −0.554335771  
                 0.554335771 
               
               
                 EIF3H 
                 −0.058134393  
                 −0.069187344 
                 0.426115156 
                 −0.553436893  
                 0.553436893 
               
               
                 FPR1 
                 −0.162620214 
                 0.013841 
                 0.404412125 
                 −0.553191339  
                 0.553191339 
               
               
                 SLC40A1 
                 −0.174765179  
                 −0.084959656 
                 0.2901025 
                 −0.549827335  
                 0.549827335 
               
               
                 NUP160 
                 −0.023343321  
                 −0.093974831 
                 0.432388269 
                 −0.549706421  
                 0.549706421 
               
               
                 ENPP5 
                 0.035325664 
                 0.1957733 
                 0.778261925 
                 −0.547162961  
                 0.547162961 
               
               
                 MARCH1 
                 −0.175800229 
                 0.011747531 
                 0.381939919 
                 −0.545992616  
                 0.545992616 
               
               
                 DPYD 
                 −0.177738393  
                 −0.109984838 
                 0.256353806 
                 −0.544077037  
                 0.544077037 
               
               
                 TGFBI 
                 −0.106554929  
                 −0.098723625 
                 0.337612906 
                 −0.54289146 
                 0.54289146 
               
               
                 FBXO5 
                 0.010836921  
                 −0.242645981 
                 0.310992263 
                 −0.542801322  
                 0.542801322 
               
               
                 ATP5L 
                 −0.144960714  
                 −0.094053063 
                 0.301385187 
                 −0.540398964  
                 0.540398964 
               
               
                 G3BP2 
                 −0.11234  
                 −0.005620688 
                 0.419481844 
                 −0.537442531  
                 0.537442531 
               
               
                 MARCKS 
                 −0.104609857  
                 −0.143516469 
                 0.287992844 
                 −0.53611917 
                 0.53611917 
               
               
                 SEC63 
                 −0.137641714  
                 −0.015913837 
                 0.381527888 
                 −0.535083439  
                 0.535083439 
               
               
                 COX6A1 
                 −0.101929893  
                 −0.099744875 
                 0.331444625 
                 −0.533119393  
                 0.533119393 
               
               
                 PDGFA 
                 0.138137329 
                 0.066844713 
                 −0.327700538 
                 0.532682579  
                 0.532682579 
               
               
                 CDT1 
                 0.192584229 
                 0.285041244 
                 −0.050867625 
                 0.528493097  
                 0.528493097 
               
               
                 KLRB1 
                 −0.158156529 
                 0.037751856 
                 0.40706125 
                 −0.527465922  
                 0.527465922 
               
               
                 SMC2 
                 −0.257334636 
                 0.049506637 
                 0.315906338 
                 −0.523734336  
                 0.523734336 
               
               
                 HLA-DMB 
                 −0.1101265 
                 −0.04071075 
                 0.3716505 
                 −0.52248775 
                 0.52248775 
               
               
                 TYROBP 
                 −0.094629357  
                 −0.082295813 
                 0.345559625 
                 −0.522484795  
                 0.522484795 
               
               
                 GLT8D2 
                 0.019518921  
                 −0.049303425 
                 0.491399144 
                 −0.521183647  
                 0.521183647 
               
               
                 GMNN 
                 −0.091846936  
                 −0.034380125 
                 0.394157213 
                 −0.520384273  
                 0.520384273 
               
               
                 FGR 
                 −0.145875929  
                 −0.074496219 
                 0.298854313 
                 −0.51922646 
                 0.51922646 
               
               
                 COX5B 
                 −0.0485035  
                 −0.072662125 
                 0.396214906 
                 −0.517380531  
                 0.517380531 
               
               
                 KIF18A 
                 0.356767059 
                 0.233752233 
                 0.074428434 
                 0.516090859  
                 0.516090859 
               
               
                 KIF20B 
                 −0.096148593  
                 −0.117388763 
                 0.300891063 
                 −0.514428418  
                 0.514428418 
               
               
                 HOXD10 
                 0.632420936 
                 0.239668344 
                 0.359192931 
                 0.512896348  
                 0.512896348 
               
               
                 RAD21 
                 −0.094918893  
                 −0.085931906 
                 0.331705812 
                 −0.512556612  
                 0.512556612 
               
               
                 MATR3 
                 −0.104278193  
                 −0.021778331 
                 0.386447731 
                 −0.512504255  
                 0.512504255 
               
               
                 APOBEC3B 
                 −0.205192143  
                 −0.102170781 
                 0.203892688 
                 −0.511255612  
                 0.511255612 
               
               
                 HMOX1 
                 −0.128383179  
                 −0.123476031 
                 0.258965875 
                 −0.510825085  
                 0.510825085 
               
               
                 SLC31A2 
                 −0.181080679  
                 −0.067661719 
                 0.261799219 
                 −0.510541616  
                 0.510541616 
               
               
                 VNN3 
                 −0.206968286  
                 −0.096329569 
                 0.201148394 
                 −0.504446248  
                 0.504446248 
               
               
                 TSPAN5 
                 0.244892929 
                 −0.06738175 
                 −0.323473044 
                 0.500984222  
                 0.500984222 
               
               
                 GATA1 
                 0.292226893 
                 0.104003775 
                 −0.102690375 
                 0.498921043  
                 0.498921043 
               
               
                 MARCO 
                 −0.1259919 
                 0.027786294 
                 0.3990929 
                 −0.497298506  
                 0.497298506 
               
               
                 SIRPB2 
                 −0.196183571 
                 0.061583687 
                 0.358098994 
                 −0.492698878  
                 0.492698878 
               
               
                 LST1 
                 −0.149602786 
                 −0.06008475 
                 0.281335125 
                 −0.491022661  
                 0.491022661 
               
               
                 CEACAM7 
                 0.306448264  
                 −0.125145288 
                 −0.309436544 
                 0.490739521  
                 0.490739521 
               
               
                 KIF20A 
                 0.233543341 
                 0.129709219 
                 −0.127108786 
                 0.490361346  
                 0.490361346 
               
               
                 EED 
                 −0.114456714 
                 0.0091522 
                 0.382570156 
                 −0.487874671  
                 0.487874671 
               
               
                 RAB31 
                 −0.149398929  
                 −0.094196406 
                 0.244100281 
                 −0.487695616  
                 0.487695616 
               
               
                 NDUFB6 
                 −0.110910071 
                 −0.048859 
                 0.327792125 
                 −0.487561196  
                 0.487561196 
               
               
                 HSPE1 
                 −0.0697995  
                 −0.012676531 
                 0.404518219 
                 −0.48699425 
                 0.48699425 
               
               
                 TMEM154 
                 −0.173941464  
                 −0.048407781 
                 0.262545125 
                 −0.484894371  
                 0.484894371 
               
               
                 TLR1 
                 −0.097821071  
                 −0.081679344 
                 0.305166437 
                 −0.484666853  
                 0.484666853 
               
               
                 CD14 
                 −0.208618036  
                 −0.051658563 
                 0.223004937 
                 −0.483281536  
                 0.483281536 
               
               
                 SPC25 
                 0.062161971 
                 0.0350892 
                 0.575205913 
                 −0.477954741  
                 0.477954741 
               
               
                 ASGR1 
                 −0.1607095  
                 −0.008193156 
                 0.307480156 
                 −0.476382812  
                 0.476382812 
               
               
                 STK26 
                 −0.13457105  
                 −0.217412675 
                 0.124148462 
                 −0.476132187  
                 0.476132187 
               
               
                 EVI5 
                 −0.132586436 
                 0.043848456 
                 0.387096088 
                 −0.475834067  
                 0.475834067 
               
               
                 SLC35B3 
                 0.020614057 
                 −0.0244136 
                 0.469842775 
                 −0.473642318  
                 0.473642318 
               
               
                 FBXW2 
                 −0.132826129  
                 −0.051475106 
                 0.2891366 
                 −0.473437835  
                 0.473437835 
               
               
                 TLR6 
                 −0.060246393  
                 −0.074889556 
                 0.33679665 
                 −0.471932599  
                 0.471932599 
               
               
                 EMILIN2 
                 −0.184897107  
                 −0.021353875 
                 0.264784219 
                 −0.471035201  
                 0.471035201 
               
               
                 CCNB1 
                 −0.00534135 
                 0.045066525 
                 −0.424402231 
                 0.464127406  
                 0.464127406 
               
               
                 HLA-DRB1 
                 −0.030511964  
                 −0.084263563 
                 0.347531469 
                 −0.462306996  
                 0.462306996 
               
               
                 GAS1 
                 0.706006857  
                 −0.370432569 
                 −0.126699725 
                 0.462274013  
                 0.462274013 
               
               
                 RNASE2 
                 −0.126518993 
                 0.061956337 
                 0.396981 
                 −0.461543655  
                 0.461543655 
               
               
                 CTSH 
                 −0.080287786  
                 −0.022522656 
                 0.357824813 
                 −0.460635254  
                 0.460635254 
               
               
                 PILRA 
                 −0.144449464  
                 −0.023444219 
                 0.292670375 
                 −0.460564058  
                 0.460564058 
               
               
                 S1PR3 
                 −0.013708679  
                 −0.113372613 
                 0.332896331 
                 −0.459977622  
                 0.459977622 
               
               
                 TNF 
                 −0.09332625  
                 −0.146601688 
                 0.219674388 
                 −0.459602325  
                 0.459602325 
               
               
                 IL1RN 
                 −0.148671  
                 −0.016940094 
                 0.293804406 
                 −0.4594155 
                 0.4594155 
               
               
                 CEP55 
                 −0.117062229 
                 0.007737219 
                 0.349900525 
                 −0.459225535  
                 0.459225535 
               
               
                 ECT2 
                 0.122074414  
                 −0.210264431 
                 0.368810144 
                 −0.457000161  
                 0.457000161 
               
               
                 AQP9 
                 −0.145872286  
                 −0.093673875 
                 0.216232344 
                 −0.455778504  
                 0.455778504 
               
               
                 NDUFAB1 
                 −0.040424964  
                 −0.031471563 
                 0.382994375 
                 −0.454890902  
                 0.454890902 
               
               
                 SLA 
                 −0.000813893  
                 −0.049338625 
                 0.404489031 
                 −0.454641549  
                 0.454641549 
               
               
                 FES 
                 −0.125205321  
                 −0.048358844 
                 0.280610906 
                 −0.454175071  
                 0.454175071 
               
               
                 HSPA6 
                 −0.096868036 
                 −0.0902495 
                 0.266483469 
                 −0.453601004  
                 0.453601004 
               
               
                 RNF130 
                 −0.043926929  
                 −0.130700938 
                 0.278100375 
                 −0.452728241  
                 0.452728241 
               
               
                 CEP120 
                 −0.070382471  
                 −0.424163256 
                 −0.041858012 
                 −0.452687715  
                 0.452687715 
               
               
                 PNPLA8 
                 −0.131805071 
                 −0.098537 
                 0.221471156 
                 −0.451813228  
                 0.451813228 
               
               
                 HLA-DRB4 
                 −0.101285143  
                 −0.062042563 
                 0.287547938 
                 −0.450875643  
                 0.450875643 
               
               
                 ZBED5 
                 0.160821464 
                 −0.1594155 
                 0.450142688 
                 −0.448736723  
                 0.448736723 
               
               
                 RANBP1 
                 −0.1626735 
                 0.143935363 
                 0.428623312 
                 −0.44736145 
                 0.44736145 
               
               
                 MORF4L2 
                 −0.106883443  
                 −0.055327206 
                 0.284950756 
                 −0.447161405  
                 0.447161405 
               
               
                 PADI2 
                 −0.143229757  
                 −0.038802994 
                 0.264994838 
                 −0.447027588  
                 0.447027588 
               
               
                 TPX2 
                 0.0290026 
                 0.380640269 
                 −0.036550481 
                 0.44619335 
                 0.44619335 
               
               
                 NEK2 
                 0.103340043 
                 0.318715881 
                 −0.023429244 
                 0.445485168  
                 0.445485168 
               
               
                 EPB42 
                 0.275517036 
                 0.066022594 
                 −0.103539594 
                 0.445079223  
                 0.445079223 
               
               
                 ARMC1 
                 −0.10337225  
                 −0.046463075 
                 0.290383863 
                 −0.440219188  
                 0.440219188 
               
               
                 SMARCA5 
                 0.07529565 
                 0.081833119 
                 −0.281553706 
                 0.438682475  
                 0.438682475 
               
               
                 CSF1R 
                 −0.024051321  
                 −0.119220813 
                 0.2941795 
                 −0.437451634  
                 0.437451634 
               
               
                 ATP5J2 
                 −0.151913893  
                 −0.044919719 
                 0.239247969 
                 −0.43608158 
                 0.43608158 
               
               
                 RPA3 
                 −0.212202643 
                 0.118521156 
                 0.341430438 
                 −0.435111924  
                 0.435111924 
               
               
                 SMARCD3 
                 −0.160738571  
                 −0.034559813 
                 0.237403562 
                 −0.432701946  
                 0.432701946 
               
               
                 EIF3K 
                 0.006367607  
                 −0.050250937 
                 0.384884031 
                 −0.428767362  
                 0.428767362 
               
               
                 GPR56 
                 0.248091393 
                 0.253490812 
                 0.073507031 
                 0.428075174  
                 0.428075174 
               
               
                 ATP5I 
                 −0.226922214 
                 0.147404594 
                 0.348038938 
                 −0.427556558  
                 0.427556558 
               
               
                 NIF3L1 
                 −0.026661943  
                 −0.056488794 
                 0.341900894 
                 −0.42505163 
                 0.42505163 
               
               
                 CD53 
                 −0.074409643 
                 0.015283625 
                 0.365545125 
                 −0.424671143  
                 0.424671143 
               
               
                 MGST1 
                 −0.077665114 
                 0.044218675 
                 0.38925555 
                 −0.422701989  
                 0.422701989 
               
               
                 COX7A2L 
                 −0.025108571  
                 −0.088414375 
                 0.308798 
                 −0.422320946  
                 0.422320946 
               
               
                 FCGR1B 
                 −0.244800429  
                 −0.064144188 
                 0.112213438 
                 −0.421158054  
                 0.421158054 
               
               
                 KCNE3 
                 −0.131369571  
                 −0.086003438 
                 0.203527313 
                 −0.420900321  
                 0.420900321 
               
               
                 XPO1 
                 −0.081257921 
                 0.018815275 
                 0.35681695 
                 −0.419259596  
                 0.419259596 
               
               
                 PDE6D 
                 −0.006646264  
                 −0.010540344 
                 0.401125363 
                 −0.418311971  
                 0.418311971 
               
               
                 MS4A6A 
                 −0.125765393  
                 −0.039039156 
                 0.253117937 
                 −0.417922487  
                 0.417922487 
               
               
                 FBL 
                 0.014052786  
                 −0.040557875 
                 0.3913615 
                 −0.417866589  
                 0.417866589 
               
               
                 SIRPB1 
                 0.001492071 
                 0.268654588 
                 −0.145668094 
                 0.415814753  
                 0.415814753 
               
               
                 RAD51 
                 0.091396443 
                 0.185171756 
                 −0.138751738 
                 0.415319937  
                 0.415319937 
               
               
                 PLBD1 
                 −0.148141286  
                 −0.029220937 
                 0.237610156 
                 −0.414972379  
                 0.414972379 
               
               
                 LAT2 
                 −0.091685357  
                 −0.050819656 
                 0.271164531 
                 −0.413669545  
                 0.413669545 
               
               
                 LILRB3 
                 −0.114279071  
                 −0.103150719 
                 0.19605325 
                 −0.41348304 
                 0.41348304 
               
               
                 LILRA5 
                 −0.214061843  
                 −0.042955475 
                 0.156297888 
                 −0.413315205  
                 0.413315205 
               
               
                 PRIM1 
                 −0.063817571  
                 −0.033363275 
                 0.315208994 
                 −0.41238984 
                 0.41238984 
               
               
                 CFD 
                 0.093822357  
                 −0.059507156 
                 0.446115375 
                 −0.411800174  
                 0.411800174 
               
               
                 NCF2 
                 −0.095531464 
                 0.057808937 
                 0.373561219 
                 −0.411283746  
                 0.411283746 
               
               
                 NDUFA2 
                 −0.068903929  
                 −0.064259906 
                 0.278068969 
                 −0.411232804  
                 0.411232804 
               
               
                 SMPDL3A 
                 −0.042925271  
                 −0.039885175 
                 0.32809285 
                 −0.410903296  
                 0.410903296 
               
               
                 AGTRAP 
                 −0.154270893 
                 0.011986469 
                 0.267882563 
                 −0.410166987  
                 0.410166987 
               
               
                 GIMAP7 
                 −0.106066571 
                 0.085459281 
                 0.389390281 
                 −0.409997571  
                 0.409997571 
               
               
                 IRAK3 
                 −0.055851193  
                 −0.049636381 
                 0.302656369 
                 −0.408143943  
                 0.408143943 
               
               
                 ASGR2 
                 −0.228676107 
                 0.05324825 
                 0.232312313 
                 −0.40774017 
                 0.40774017 
               
               
                 UQCRC1 
                 −0.094910286  
                 −0.061424375 
                 0.250938906 
                 −0.407273567  
                 0.407273567 
               
               
                 CD36 
                 −0.087890679  
                 −0.026308156 
                 0.29306775 
                 −0.407266585  
                 0.407266585 
               
               
                 CD33 
                 −0.069894214  
                 −0.020831219 
                 0.315814469 
                 −0.406539902  
                 0.406539902 
               
               
                 PSAP 
                 −0.107558786  
                 −0.003443781 
                 0.294580281 
                 −0.405582848  
                 0.405582848 
               
               
                 RAD51C 
                 −0.068298621 
                 0.081866631 
                 0.418556406 
                 −0.404988396  
                 0.404988396 
               
               
                 LCP1 
                 −0.095719357 
                 0.037039969 
                 0.345936844 
                 −0.404616232  
                 0.404616232 
               
               
                 BCL6 
                 −0.116291893  
                 −0.126068313 
                 0.162234313 
                 −0.404594518  
                 0.404594518 
               
               
                 LILRA6 
                 −0.082732143  
                 −0.056291844 
                 0.262668219 
                 −0.401692205  
                 0.401692205 
               
               
                 CCT8 
                 −0.056735286 
                 0.029709437 
                 0.373685594 
                 −0.400711442  
                 0.400711442 
               
               
                 ACSL1 
                 −0.072008321  
                 −0.141371812 
                 0.18713075 
                 −0.400510884  
                 0.400510884 
               
               
                 HCLS1 
                 −0.05346175 
                 −0.018238 
                 0.328341781 
                 −0.400041531  
                 0.400041531 
               
               
                 ITGA4 
                 −0.021362636 
                 0.017255644 
                 0.395887519 
                 −0.399994511  
                 0.399994511 
               
               
                 SULF2 
                 −0.175644286 
                 0.007419937 
                 0.231142375 
                 −0.399366723  
                 0.399366723 
               
               
                 CRTAM 
                 0.005827757 
                 0.005227244 
                 0.409946113 
                 −0.398891112  
                 0.398891112 
               
               
                 CCT4 
                 0.048661071 
                 0.030773688 
                 0.475969125 
                 −0.396534366  
                 0.396534366 
               
               
                 CHRDL1 
                 −0.187312629 
                 0.15926425 
                 −0.420098525 
                 0.392050146  
                 0.392050146 
               
               
                 GZMA 
                 −0.119411321 
                 0.071365812 
                 0.343343812 
                 −0.391389321  
                 0.391389321 
               
               
                 PGD 
                 −0.075605786  
                 −0.079848531 
                 0.233971188 
                 −0.389425504  
                 0.389425504 
               
               
                 ARID4B 
                 −0.098521307  
                 −0.038940956 
                 0.251950206 
                 −0.38941247 
                 0.38941247 
               
               
                 RFC4 
                 −0.064330557 
                 0.042476944 
                 0.367389475 
                 −0.389243088  
                 0.389243088 
               
               
                 TNFRSF10B 
                 −0.099273321  
                 −0.096856187 
                 0.192978219 
                 −0.389107728  
                 0.389107728 
               
               
                 POLD3 
                 −0.097467114 
                 0.016328319 
                 0.307658844 
                 −0.388797639  
                 0.388797639 
               
               
                 UQCRFS1 
                 −0.020328964  
                 −0.001193125 
                 0.366491781 
                 −0.388013871  
                 0.388013871 
               
               
                 ROCK1 
                 −0.015296636  
                 −0.130577269 
                 0.241015525 
                 −0.386889429  
                 0.386889429 
               
               
                 NDUFS3 
                 −0.05276875 
                 0.028971156 
                 0.361374563 
                 −0.385172156  
                 0.385172156 
               
               
                 CCT3 
                 0.022924643 
                 0.030373906 
                 0.434754688 
                 −0.381456138  
                 0.381456138 
               
               
                 HLA-DMA 
                 −0.064727036 
                 −0.095813 
                 0.220344813 
                 −0.380884848  
                 0.380884848 
               
               
                 GP9 
                 0.098050357 
                 0.230333563 
                 −0.051893531 
                 0.380277451  
                 0.380277451 
               
               
                 MYD88 
                 −0.113476607 
                 0.062618813 
                 0.329212625 
                 −0.38007042 
                 0.38007042 
               
               
                 SH2D1A 
                 −0.150883521  
                 −0.100137519 
                 0.128488456 
                 −0.379509496  
                 0.379509496 
               
               
                 NCF1 
                 −0.124598929  
                 −0.031149125 
                 0.22353825 
                 −0.379286304  
                 0.379286304 
               
               
                 CD27 
                 0.142986429  
                 −0.015922438 
                 −0.251951625 
                 0.379015616  
                 0.379015616 
               
               
                 SPRY4 
                 0.37953555  
                 −0.069613044 
                 −0.067842113 
                 0.377764619  
                 0.377764619 
               
               
                 NLGN1 
                 −0.135739121  
                 −0.440554081 
                 −0.199182031 
                 −0.377111171  
                 0.377111171 
               
               
                 HPSE 
                 −0.276072121  
                 −0.044384475 
                 0.056582837 
                 −0.377039434  
                 0.377039434 
               
               
                 MED23 
                 −0.081364179 
                 0.045862488 
                 0.341019063 
                 −0.376520754  
                 0.376520754 
               
               
                 UBE2T 
                 −0.096130436  
                 −0.064383438 
                 0.214767288 
                 −0.375281161  
                 0.375281161 
               
               
                 LILRA2 
                 −0.109144071  
                 −0.061932719 
                 0.201981906 
                 −0.373058696  
                 0.373058696 
               
               
                 LEF1 
                 0.05173875 
                 0.016449531 
                 0.440937813 
                 −0.372749531  
                 0.372749531 
               
               
                 KNTC1 
                 0.03019865 
                 0.021303213 
                 0.422944694 
                 −0.371442831  
                 0.371442831 
               
               
                 ACPP 
                 −0.052862964  
                 −0.038900388 
                 0.278133725 
                 −0.369897077  
                 0.369897077 
               
               
                 APOBEC3A 
                 −0.091132643  
                 −0.059349375 
                 0.218231219 
                 −0.368713237  
                 0.368713237 
               
               
                 GOLPH3L 
                 −0.116393657  
                 −0.058737531 
                 0.193511413 
                 −0.368642601  
                 0.368642601 
               
               
                 UQCRH 
                 −0.174240321 
                 0.067663719 
                 0.261680406 
                 −0.368257009  
                 0.368257009 
               
               
                 SLC7A7 
                 −0.075728964 
                 −0.03531975 
                 0.256691094 
                 −0.367739808  
                 0.367739808 
               
               
                 FGFBP2 
                 −0.026483621 
                 0.044735331 
                 0.385422 
                 −0.36717029 
                 0.36717029 
               
               
                 TMPO 
                 0.056282186 
                 −0.05915685 
                 0.362219844 
                 −0.365094508  
                 0.365094508 
               
               
                 CEP76 
                 0.057769386 
                 −0.11883195 
                 0.304023344 
                 −0.365085908  
                 0.365085908 
               
               
                 CPVL 
                 −0.121587907  
                 −0.057256063 
                 0.185360906 
                 −0.364204876  
                 0.364204876 
               
               
                 IL10RA 
                 −0.093252321 
                 0.061976562 
                 0.331903094 
                 −0.363178853  
                 0.363178853 
               
               
                 TYMS 
                 0.215262371 
                 0.229346038 
                 0.081789275 
                 0.362819134  
                 0.362819134 
               
               
                 TSN 
                 −0.051023429 
                 0.004856975 
                 0.315315175 
                 −0.361481629  
                 0.361481629 
               
               
                 CDC25A 
                 0.203142321  
                 −0.116647119 
                 −0.274576838 
                 0.36107204 
                 0.36107204 
               
               
                 CKS1B 
                 −0.063159979  
                 −0.033092825 
                 0.264611125 
                 −0.360863929  
                 0.360863929 
               
               
                 GPR171 
                 −0.129736571 
                 0.101393125 
                 0.331161438 
                 −0.359504884  
                 0.359504884 
               
               
                 POLA2 
                 0.030734921  
                 −0.042516512 
                 0.345878394 
                 −0.357659985  
                 0.357659985 
               
               
                 CLK1 
                 −0.101373336  
                 −0.065989581 
                 0.190234075 
                 −0.357596992  
                 0.357596992 
               
               
                 RAN 
                 0.0305255 
                 0.0161995 
                 0.403059781 
                 −0.356334781  
                 0.356334781 
               
               
                 F5 
                 −0.191259607  
                 −0.063712219 
                 0.100646831 
                 −0.355618657  
                 0.355618657 
               
               
                 CD2 
                 0.01264925 
                 0.033470375 
                 0.401702594 
                 −0.355582969  
                 0.355582969 
               
               
                 NDUFA8 
                 −0.019786071 
                 0.068549906 
                 0.404028281 
                 −0.355264446  
                 0.355264446 
               
               
                 RBM47 
                 −0.069904107 
                 0.003304031 
                 0.288030781 
                 −0.354630857  
                 0.354630857 
               
               
                 CST3 
                 −0.126935536  
                 −0.025867938 
                 0.201113344 
                 −0.353916817  
                 0.353916817 
               
               
                 NDUFA11 
                 −0.016871929 
                 0.005966313 
                 0.342687969 
                 −0.353593585  
                 0.353593585 
               
               
                 SKA3 
                 0.100919436 
                 0.177433125 
                 −0.073734256 
                 0.352086817  
                 0.352086817 
               
               
                 EIF3D 
                 0.020153786  
                 −0.065306187 
                 0.306289719 
                 −0.351442121  
                 0.351442121 
               
               
                 FHL2 
                 0.000630921 
                 0.214066981 
                 −0.135850413 
                 0.350548315  
                 0.350548315 
               
               
                 MAFB 
                 0.001780571  
                 −0.078602094 
                 0.272882656 
                 −0.349704179  
                 0.349704179 
               
               
                 TLK1 
                 −0.081011579 
                 0.047498619 
                 0.31585145 
                 −0.34936441 
                 0.34936441 
               
               
                 CHAC2 
                 −0.109671707  
                 −0.180782856 
                 0.058605019 
                 −0.349059582  
                 0.349059582 
               
               
                 RAB21 
                 −0.080717893  
                 −0.034387687 
                 0.233636156 
                 −0.348741737  
                 0.348741737 
               
               
                 COX6B1 
                 −0.05439875  
                 −0.012977531 
                 0.280276125 
                 −0.347652406  
                 0.347652406 
               
               
                 GPR18 
                 −0.047635314  
                 −0.086936481 
                 0.210504875 
                 −0.345076671  
                 0.345076671 
               
               
                 SLAMF1 
                 −0.138963829  
                 −0.005397137 
                 0.197378794 
                 −0.34173976 
                 0.34173976 
               
               
                 NUP88 
                 −0.016508186  
                 −0.058129887 
                 0.266949519 
                 −0.341587592  
                 0.341587592 
               
               
                 UQCRC2 
                 −0.057371893 
                 0.025039281 
                 0.303439531 
                 −0.335772143  
                 0.335772143 
               
               
                 BRCA1 
                 −0.155206629  
                 −0.018376169 
                 0.161965494 
                 −0.335548291  
                 0.335548291 
               
               
                 CYFIP1 
                 −0.060388986  
                 −0.015578656 
                 0.258815819 
                 −0.334783461  
                 0.334783461 
               
               
                 TMOD1 
                 0.194032093 
                 0.014683806 
                 −0.124742444 
                 0.333458343  
                 0.333458343 
               
               
                 TIPIN 
                 0.180150893  
                 −0.032065738 
                 0.481311544 
                 −0.333226388  
                 0.333226388 
               
               
                 COX8A 
                 −0.017822929  
                 −0.005128219 
                 0.309650406 
                 −0.332601554  
                 0.332601554 
               
               
                 LILRB2 
                 −0.082981571  
                 −0.058156344 
                 0.191195625 
                 −0.33233354 
                 0.33233354 
               
               
                 RFC2 
                 −0.028812529  
                 −0.014747981 
                 0.287979225 
                 −0.331539735  
                 0.331539735 
               
               
                 IL13RA1 
                 −0.090803679 
                 0.109964344 
                 0.350655125 
                 −0.33149446 
                 0.33149446 
               
               
                 CD300LF 
                 −0.05083975  
                 −0.062153219 
                 0.218185469 
                 −0.331178438  
                 0.331178438 
               
               
                 NCF4 
                 −0.07311125  
                 −0.034869719 
                 0.222047906 
                 −0.330028875  
                 0.330028875 
               
               
                 RRM1 
                 −0.05435685  
                 −0.034887119 
                 0.240450581 
                 −0.32969455 
                 0.32969455 
               
               
                 ELAVL3 
                 0.373095546  
                 −0.024622615 
                 0.01926285 
                 0.329210081  
                 0.329210081 
               
               
                 LTBR 
                 −0.160517679  
                 −0.091051437 
                 0.0769038 
                 −0.328472916  
                 0.328472916 
               
               
                 ALOX5 
                 −0.097675857 
                 −0.025537 
                 0.203811688 
                 −0.327024545  
                 0.327024545 
               
               
                 PLAUR 
                 −0.143859321 
                 0.005075062 
                 0.186813438 
                 −0.325597696  
                 0.325597696 
               
               
                 CRISPLD2 
                 −0.2434387  
                 −0.018830487 
                 0.062991538 
                 −0.325260725  
                 0.325260725 
               
               
                 PYGL 
                 −0.116781321  
                 −0.027644562 
                 0.180310781 
                 −0.324736665  
                 0.324736665 
               
               
                 MDFIC 
                 −0.222482193 
                 0.115050188 
                 0.217266475 
                 −0.32469848 
                 0.32469848 
               
               
                 CFP 
                 −0.121672286  
                 −0.045736219 
                 0.156494219 
                 −0.323902723  
                 0.323902723 
               
               
                 KIF2C 
                 0.215050936  
                 −0.030802981 
                 −0.138030888 
                 0.322278842  
                 0.322278842 
               
               
                 HCK 
                 −0.058467464  
                 −0.040651875 
                 0.223122531 
                 −0.322241871  
                 0.322241871 
               
               
                 THEMIS 
                 −0.030008079 
                 0.077853244 
                 0.369118469 
                 −0.321273304  
                 0.321273304 
               
               
                 KIAA1598 
                 0.226799843  
                 −0.125207913 
                 0.422753275 
                 −0.321161345 
                 0.321161345 
               
               
                 IL1R2 
                 −0.077493407 
                 0.041097838 
                 0.284015131 
                 −0.320410701 
                 0.320410701 
               
               
                 FAM83D 
                 −0.013678003  
                 −0.252206619 
                 0.053864803 
                 −0.319749425 
                 0.319749425 
               
               
                 CXCR2 
                 −0.097071286 
                 0.001763562 
                 0.224435781 
                 −0.319743504 
                 0.319743504 
               
               
                 RTN1 
                 0.086391936  
                 −0.013562106 
                 0.391497244 
                 −0.318667414 
                 0.318667414 
               
               
                 TIMP2 
                 −0.066331929 
                 0.056842875 
                 0.307963156 
                 −0.31745221 
                 0.31745221 
               
               
                 GATA3 
                 −0.077782507 
                 0.018922819 
                 0.257456344 
                 −0.316316032 
                 0.316316032 
               
               
                 UBA3 
                 −0.116247871 
                 0.034844356 
                 0.234209469 
                 −0.315612984 
                 0.315612984 
               
               
                 PRRX1 
                 0.21504705 
                 0.1026264 
                 0.002564387 
                 0.315109063 
                 0.315109063 
               
               
                 NLRP3 
                 −0.099970607 
                 0.025493031 
                 0.240302719 
                 −0.314780295 
                 0.314780295 
               
               
                 UHRF1 
                 −0.065325229  
                 −0.332139738  
                 −0.711249206 
                 0.31378424 
                 0.31378424 
               
               
                 OIP5 
                 0.082459536  
                 −0.051354256 
                 0.344000944 
                 −0.312895664 
                 0.312895664 
               
               
                 PAK1 
                 −0.078231214 
                 0.004895375 
                 0.239366437 
                 −0.312702277 
                 0.312702277 
               
               
                 LY86 
                 −0.091854214 
                 −0.00419325 
                 0.216384781 
                 −0.312432246 
                 0.312432246 
               
               
                 KLRD1 
                 0.136897079 
                 0.334659263 
                 0.159358556 
                 0.312197785 
                 0.312197785 
               
               
                 DTL 
                 0.002756621 
                 0.090291919 
                 0.404853569 
                 −0.311805029 
                 0.311805029 
               
               
                 SIRPA 
                 −0.091310143 
                 0.054190688 
                 0.274285937 
                 −0.311405393 
                 0.311405393 
               
               
                 TRAT1 
                 −0.162242243 
                 0.083363331 
                 0.232039775 
                 −0.310918687 
                 0.310918687 
               
               
                 RASSF4 
                 −0.075619321 
                 −0.01065925 
                 0.222700469 
                 −0.30897904 
                 0.30897904 
               
               
                 PECAM1 
                 −0.07363625  
                 −0.060431938 
                 0.174908031 
                 −0.308976219 
                 0.308976219 
               
               
                 RFC3 
                 0.123554629 
                 0.092185369  
                 −0.092420456 
                 0.308160454 
                 0.308160454 
               
               
                 ACTL6A 
                 0.052985686  
                 −0.039293506 
                 0.321694169 
                 −0.308001989 
                 0.308001989 
               
               
                 CHEK1 
                 −0.038283775 
                 0.139021444 
                 0.408487894 
                 −0.307750225 
                 0.307750225 
               
               
                 BUB1 
                 0.132609543 
                 0.251248256 
                 0.691503475 
                 −0.307645676 
                 0.307645676 
               
               
                 PYCARD 
                 −0.023505893 
                 0.005845094 
                 0.289019406 
                 −0.306680205 
                 0.306680205 
               
               
                 EIF3F 
                 −0.055520607 
                 0.026444656 
                 0.276166344 
                 −0.305242295 
                 0.305242295 
               
               
                 ARHGEF10L 
                 −0.103017607  
                 −0.023003438 
                 0.178905688 
                 −0.304926732 
                 0.304926732 
               
               
                 ITM2A 
                 −0.040229429  
                 −0.003932375 
                 0.260308 
                 −0.304469804 
                 0.304469804 
               
               
                 LILRB1 
                 −0.039777321  
                 −0.074463563 
                 0.187777313 
                 −0.302018196 
                 0.302018196 
               
               
                 NUP37 
                 0.023116864 
                 0.00830125 
                 0.333344706 
                 −0.301926592 
                 0.301926592 
               
               
                 GIMAP6 
                 0.04174575 
                 0.040583437 
                 0.383533563 
                 −0.301204375 
                 0.301204375 
               
               
                 EVI2B 
                 −0.095254571 
                 0.010024438 
                 0.215455906 
                 −0.30068604 
                 0.30068604 
               
               
                 C1S 
                 0.258450671  
                 −0.256533794  
                 −0.298766269 
                 0.300683146 
                 0.300683146 
               
               
                 RASGRP1 
                 −0.014854864 
                 −0.03644825 
                 0.248511125 
                 −0.299814239 
                 0.299814239 
               
               
                 PRKAR2B 
                 0.073416286 
                 0.265515313 
                 0.039988094 
                 0.298943504 
                 0.298943504 
               
               
                 AGPAT9 
                 −0.1247355  
                 −0.055078937 
                 0.11891075 
                 −0.298725187 
                 0.298725187 
               
               
                 FPR2 
                 0.1502825 
                 0.290507219 
                 0.147100688 
                 0.293689031 
                 0.293689031 
               
               
                 AURKB 
                 −0.055779007  
                 −0.010595813 
                 0.227200356 
                 −0.293575176 
                 0.293575176 
               
               
                 TNFAIP2 
                 −0.040341571  
                 −0.026401312 
                 0.226633688 
                 −0.293376571 
                 0.293376571 
               
               
                 NUP62 
                 −0.053117464 
                 0.056916312 
                 0.297069625 
                 −0.293270777 
                 0.293270777 
               
               
                 EIF3G 
                 −0.042194 
                 0.005646562 
                 0.254368094 
                 −0.290915531 
                 0.290915531 
               
               
                 GOPC 
                 0.317457793  
                 −0.152528806 
                 0.455231825 
                 −0.290302838 
                 0.290302838 
               
               
                 CCT7 
                 −0.003881321 
                 0.017706781 
                 0.3038845 
                 −0.29005904 
                 0.29005904 
               
               
                 IMPA2 
                 0.018998714 
                 0.001092125 
                 0.3094655 
                 −0.289374661 
                 0.289374661 
               
               
                 UPF3B 
                 −0.0048737 
                 0.106697188 
                 0.390858644 
                 −0.289035156 
                 0.289035156 
               
               
                 SACM1L 
                 −0.037368293 
                 0.019169344 
                 0.270208994 
                 −0.288407943 
                 0.288407943 
               
               
                 CSF3R 
                 −0.107332786  
                 −0.055135406 
                 0.12043925 
                 −0.282907442 
                 0.282907442 
               
               
                 PVRIG 
                 0.1293885 
                 0.192957313 
                 0.040053344 
                 0.282292469 
                 0.282292469 
               
               
                 RAD54L 
                 0.044659614 
                 0.076583669 
                 0.400908406 
                 −0.279665123 
                 0.279665123 
               
               
                 ATP9A 
                 −0.018721557 
                 0.295013075  
                 −0.002296063 
                 0.27858758 
                 0.27858758 
               
               
                 NDUFB4 
                 0.022882536 
                 0.037768063 
                 0.337617125 
                 −0.276966527 
                 0.276966527 
               
               
                 HOMER3 
                 −0.161564357 
                 0.025836844 
                 0.139398125 
                 −0.275125638 
                 0.275125638 
               
               
                 TNS3 
                 −0.056496 
                 0.038417688 
                 0.256140831 
                 −0.274219144 
                 0.274219144 
               
               
                 NLRP12 
                 −0.12088475  
                 −0.031573812 
                 0.121329781 
                 −0.273788344 
                 0.273788344 
               
               
                 ADRB2 
                 0.123512536 
                 0.071676156 
                 0.468501 
                 −0.273312308 
                 0.273312308 
               
               
                 NUP43 
                 0.016272214 
                 0.011833656 
                 0.300534375 
                 −0.272428504 
                 0.272428504 
               
               
                 CCT6A 
                 0.028902071 
                 0.000999344 
                 0.301071531 
                 −0.271170116 
                 0.271170116 
               
               
                 TLR2 
                 0.061149464 
                 0.135409938 
                 0.466517625 
                 −0.269958223 
                 0.269958223 
               
               
                 FAM72A 
                 −0.163401771 
                 0.030480644 
                 0.135066594 
                 −0.267987721 
                 0.267987721 
               
               
                 SERPINA1 
                 −0.140922143  
                 −0.065372844 
                 0.061537 
                 −0.267831987 
                 0.267831987 
               
               
                 SLC24A4 
                 −0.081812479  
                 −0.068289906 
                 0.11610685 
                 −0.266209235 
                 0.266209235 
               
               
                 GLT1D1 
                 −0.113676429 
                 −0.0532025 
                 0.098683344 
                 −0.265562272 
                 0.265562272 
               
               
                 HSD17B4 
                 −0.048726514 
                 0.014324044 
                 0.231119369 
                 −0.265521839 
                 0.265521839 
               
               
                 UXT 
                 0.008390679  
                 −0.049655906 
                 0.223751813 
                 −0.26501704 
                 0.26501704 
               
               
                 CEBPA 
                 −0.063082393  
                 −0.011602812 
                 0.188959594 
                 −0.263644799 
                 0.263644799 
               
               
                 FCGR2C 
                 −0.031273143  
                 −0.036346781 
                 0.195244844 
                 −0.262864768 
                 0.262864768 
               
               
                 PTPRC 
                 −0.122061857 
                 0.008952469 
                 0.149388813 
                 −0.262498201 
                 0.262498201 
               
               
                 KLRK1 
                 −0.053411821 
                 0.059479675 
                 0.267907138 
                 −0.261839284 
                 0.261839284 
               
               
                 CX3CR1 
                 0.086424036 
                 0.090047375 
                 0.437198031 
                 −0.260726621 
                 0.260726621 
               
               
                 LYL1 
                 0.182472857 
                 0.003204219 
                 −0.07453525 
                 0.260212326 
                 0.260212326 
               
               
                 C7 
                 0.248340043  
                 −0.171803606  
                 −0.183461375 
                 0.259997812 
                 0.259997812 
               
               
                 BCL2 
                 −0.045814221 
                 0.171313662 
                 0.3841322 
                 −0.258632759 
                 0.258632759 
               
               
                 MBOAT7 
                 −0.073752321  
                 −0.061278969 
                 0.122161094 
                 −0.257192384 
                 0.257192384 
               
               
                 KIR2DL5A 
                 0.050876864 
                 0.149283706 
                 −0.0565809 
                 0.256741471 
                 0.256741471 
               
               
                 MELK 
                 0.164654093 
                 0.035156056  
                 −0.055374975 
                 0.255185124 
                 0.255185124 
               
               
                 CTNNA1 
                 −0.021998464 
                 0.054949294 
                 0.287663938 
                 −0.254713108 
                 0.254713108 
               
               
                 PLXNB2 
                 −0.080407464 
                 −0.076382 
                 0.097792812 
                 −0.254582277 
                 0.254582277 
               
               
                 SELL 
                 −0.09905125  
                 −0.052091125 
                 0.102181406 
                 −0.253323781 
                 0.253323781 
               
               
                 CRYBB3 
                 0.064264571 
                 0.18436605 
                 −0.004553106 
                 0.253183728 
                 0.253183728 
               
               
                 KLRF1 
                 0.035960571 
                 0.04410145 
                 0.332430812 
                 −0.252368791 
                 0.252368791 
               
               
                 ANLN 
                 0.00399203  
                 −0.056580606 
                 0.199374681 
                 −0.251963258 
                 0.251963258 
               
               
                 NDUFC2 
                 0.065413107 
                 0.014681656 
                 0.329968812 
                 −0.249874049 
                 0.249874049 
               
               
                 PLK4 
                 0.449380134  
                 −0.000561887 
                 0.69820218 
                 −0.249383934 
                 0.249383934 
               
               
                 DOK2 
                 0.016806536  
                 −0.011930906 
                 0.252665938 
                 −0.247790308 
                 0.247790308 
               
               
                 DOK3 
                 −0.115201607  
                 −0.041282688 
                 0.091301563 
                 −0.247785857 
                 0.247785857 
               
               
                 TBCK 
                 −0.014807386 
                 0.130582063 
                 0.362802656 
                 −0.247027979 
                 0.247027979 
               
               
                 PRKCH 
                 0.071830929 
                 0.062598125 
                 0.381239719 
                 −0.246810665 
                 0.246810665 
               
               
                 CYC1 
                 0.019239321  
                 −0.069918187 
                 0.195557469 
                 −0.246236335 
                 0.246236335 
               
               
                 ABLIM1 
                 0.060434464 
                 0.064552875 
                 0.370007188 
                 −0.245019848 
                 0.245019848 
               
               
                 EMR2 
                 −0.054620571 
                 −0.0337915 
                 0.154048406 
                 −0.242460478 
                 0.242460478 
               
               
                 P2RY13 
                 −0.074662014 
                 −0.08374915 
                 0.082303819 
                 −0.240714983 
                 0.240714983 
               
               
                 KIR3DL1 
                 0.118526179 
                 0.170095588 
                 0.049008837 
                 0.239612929 
                 0.239612929 
               
               
                 CD163 
                 −0.021365143 
                 0.019498188 
                 0.236402875 
                 −0.23826983 
                 0.23826983 
               
               
                 CDCA7 
                 0.040049543 
                 0.049382125  
                 −0.148590044 
                 0.238021712 
                 0.238021712 
               
               
                 PDGFRA 
                 0.217143546 
                 0.071091616 
                 0.051219727 
                 0.237015435 
                 0.237015435 
               
               
                 CCL4L2 
                 0.060749536 
                 0.175954719 
                 0.473478094 
                 −0.236773839 
                 0.236773839 
               
               
                 HHEX 
                 0.027009136  
                 −0.042128188 
                 0.221468875 
                 −0.236587927 
                 0.236587927 
               
               
                 KLRC3 
                 0.031305064 
                 0.134056913 
                 0.401069388 
                 −0.235707411 
                 0.235707411 
               
               
                 NDUFS7 
                 −0.046897464 
                 0.06665025 
                 0.25466375 
                 −0.234910964 
                 0.234910964 
               
               
                 GINS4 
                 0.055271907 
                 0.121248963 
                 0.410527975 
                 −0.234007105 
                 0.234007105 
               
               
                 PRAM1 
                 0.024903857  
                 −0.060584344 
                 0.198265156 
                 −0.233945643 
                 0.233945643 
               
               
                 IFNGR2 
                 −0.123364643  
                 −0.045524969 
                 0.063991406 
                 −0.232881018 
                 0.232881018 
               
               
                 KIAA0513 
                 0.000826321  
                 −0.049439281 
                 0.184025656 
                 −0.232638616 
                 0.232638616 
               
               
                 SPI1 
                 −0.095116929 
                 −0.09664825 
                 0.040667094 
                 −0.232432272 
                 0.232432272 
               
               
                 POC1A 
                 −0.019389429  
                 −0.095124331 
                 0.117207925 
                 −0.231721685 
                 0.231721685 
               
               
                 DONSON 
                 0.338211479 
                 0.065411256 
                 0.171937125 
                 0.23168561 
                 0.23168561 
               
               
                 MEGF9 
                 −0.039111643  
                 −0.021554844 
                 0.170999562 
                 −0.231666049 
                 0.231666049 
               
               
                 CDC25C 
                 0.112939829 
                 0.075938763 
                 −0.042544388 
                 0.231422979 
                 0.231422979 
               
               
                 PTGER2 
                 −0.042991157 
                 0.128184388 
                 0.315065313 
                 −0.229872082 
                 0.229872082 
               
               
                 CDCA8 
                 −0.000913593 
                 0.044746369 
                 0.273661531 
                 −0.229828755 
                 0.229828755 
               
               
                 UQCR10 
                 −0.03205 
                 0.080985719 
                 0.278651313 
                 −0.229715594 
                 0.229715594 
               
               
                 COPB2 
                 0.023108679 
                 0.011450375 
                 0.264066375 
                 −0.229507321 
                 0.229507321 
               
               
                 ALDH2 
                 −0.079059607  
                 −0.023502094 
                 0.126694219 
                 −0.22925592 
                 0.22925592 
               
               
                 RNASE6 
                 −0.171393643 
                 0.151863531 
                 0.209186938 
                 −0.228717049 
                 0.228717049 
               
               
                 STAT4 
                 0.046057929 
                 0.0061195 
                 0.279347488 
                 −0.227170059 
                 0.227170059 
               
               
                 SLC15A3 
                 −0.076069929 
                 −0.055751 
                 0.094933844 
                 −0.226754772 
                 0.226754772 
               
               
                 SLC35A5 
                 −0.041571021 
                 0.049835756 
                 0.234523494 
                 −0.226258759 
                 0.226258759 
               
               
                 PLK1 
                 1.73E−05 
                 0.21058035 
                 −0.01565185 
                 0.2262495 
                 0.2262495 
               
               
                 SMC1A 
                 0.012533143 
                 0.117303819  
                 −0.096245612 
                 0.226082574 
                 0.226082574 
               
               
                 CDK1 
                 −0.135575529 
                 0.039025156 
                 0.129455113 
                 −0.226005485 
                 0.226005485 
               
               
                 FBP1 
                 −0.059616036  
                 −0.000195656 
                 0.166176312 
                 −0.225988004 
                 0.225988004 
               
               
                 CLIC3 
                 0.165462929 
                 0.149849875 
                 0.089348594 
                 0.22596421 
                 0.22596421 
               
               
                 ETV1 
                 0.012184231  
                 −0.240764519  
                 −0.451045356 
                 0.222465069 
                 0.222465069 
               
               
                 MYO1F 
                 −0.059316857  
                 −0.018704438 
                 0.144439406 
                 −0.222460701 
                 0.222460701 
               
               
                 S100A11 
                 −0.133485 
                 −0.047393 
                 0.040467813 
                 −0.221345813 
                 0.221345813 
               
               
                 PIKFYVE 
                 0.104854321 
                 0.100655869  
                 −0.015508438 
                 0.221018628 
                 0.221018628 
               
               
                 MYOF 
                 0.01329225 
                 0.085496481 
                 0.318671794 
                 −0.219883063 
                 0.219883063 
               
               
                 AOAH 
                 −0.039758964  
                 −0.016910688 
                 0.162713031 
                 −0.219382683 
                 0.219382683 
               
               
                 CD3D 
                 −0.019660714  
                 −0.079698687 
                 0.119301125 
                 −0.218660527 
                 0.218660527 
               
               
                 TMTC2 
                 −0.056239136 
                 0.078163744 
                 0.238933619 
                 −0.217009011 
                 0.217009011 
               
               
                 SUCLG1 
                 −0.065113321 
                 0.069687812 
                 0.221268938 
                 −0.216694446 
                 0.216694446 
               
               
                 PTGDR 
                 0.163682371 
                 0.1285211 
                 0.075578575 
                 0.216624896 
                 0.216624896 
               
               
                 TREM1 
                 −0.2144935 
                 0.009985344 
                 0.011707031 
                 −0.216215188 
                 0.216215188 
               
               
                 FCGRT 
                 −0.071927429  
                 −0.021679125 
                 0.122436219 
                 −0.216042772 
                 0.216042772 
               
               
                 NUP133 
                 −0.077487443 
                 0.048664469 
                 0.185974988 
                 −0.214797962 
                 0.214797962 
               
               
                 ACBD3 
                 −0.048152843 
                 0.164027606 
                 0.329671319 
                 −0.213796555 
                 0.213796555 
               
               
                 CD8B 
                 0.062121 
                 0.077815406 
                 0.353468062 
                 −0.213531656 
                 0.213531656 
               
               
                 HELLS 
                 0.086903171 
                 0.019568225 
                 −0.1070155 
                 0.213486896 
                 0.213486896 
               
               
                 NFIA 
                 0.371265486 
                 −0.0424143 
                 0.115813775 
                 0.213037411 
                 0.213037411 
               
               
                 PTPN11 
                 −0.093143579 
                 0.070667075 
                 0.189791044 
                 −0.212267547 
                 0.212267547 
               
               
                 PRF1 
                 0.142380979 
                 0.187776544 
                 0.118929719 
                 0.211227804 
                 0.211227804 
               
               
                 NCAM1 
                 0.186510829 
                 0.170383288 
                 0.146273838 
                 0.210620279 
                 0.210620279 
               
               
                 CYBB 
                 −0.091119571  
                 −0.020434094 
                 −0.322162281 
                 0.210608616 
                 0.210608616 
               
               
                 SYK 
                 −0.06395725 
                 0.002388875 
                 0.148010469 
                 −0.209578844 
                 0.209578844 
               
               
                 TBXAS1 
                 −0.073986893  
                 −0.048228219 
                 0.086518344 
                 −0.208733455 
                 0.208733455 
               
               
                 ZAP70 
                 −0.017364357 
                 0.013869219 
                 0.203887688 
                 −0.207382826 
                 0.207382826 
               
               
                 SEMA4A 
                 −0.197552929 
                 0.03085925 
                 0.040039219 
                 −0.206732897 
                 0.206732897 
               
               
                 LYN 
                 −0.036844786  
                 −0.003103938 
                 0.165543937 
                 −0.205492661 
                 0.205492661 
               
               
                 TRIM10 
                 0.153861014 
                 0.004640925  
                 −0.046917244 
                 0.205419183 
                 0.205419183 
               
               
                 HJURP 
                 −0.013993607 
                 0.179469288 
                 0.039795713 
                 0.205271393 
                 0.205271393 
               
               
                 PRKCD 
                 −0.007103429  
                 −0.019443625 
                 0.17715875 
                 −0.203705804 
                 0.203705804 
               
               
                 KIF11 
                 0.3559893  
                 −0.363408594 
                 0.195700206 
                 −0.2031195 
                 0.2031195 
               
               
                 RHOH 
                 0.038042607 
                 0.058467281 
                 0.29882175 
                 −0.202311862 
                 0.202311862 
               
               
                 GRN 
                 0.1997915 
                 0.269006406 
                 0.266844781 
                 0.201953125 
                 0.201953125 
               
               
                 TTC1 
                 −0.045822357 
                 0.04050645 
                 0.196106169 
                 −0.201422076 
                 0.201422076 
               
               
                 ITGAM 
                 −0.034672786 
                 0.009557375 
                 0.174503438 
                 −0.199618848 
                 0.199618848 
               
               
                 RXRA 
                 −0.034103821  
                 −0.026557688 
                 0.138651594 
                 −0.199313103 
                 0.199313103 
               
               
                 NUP85 
                 0.030187679 
                 0.021720875 
                 0.250158788 
                 −0.198250234 
                 0.198250234 
               
               
                 XCL1 
                 −0.040837821  
                 −0.030924194 
                 0.12604125 
                 −0.197803265 
                 0.197803265 
               
               
                 BTK 
                 −0.246700964 
                 0.115514375 
                 0.066183563 
                 −0.197370152 
                 0.197370152 
               
               
                 KIR2DS4 
                 0.109764193 
                 0.151970006 
                 0.065144675 
                 0.196589524 
                 0.196589524 
               
               
                 GINS2 
                 0.086710507 
                 0.03973685 
                 0.321476863 
                 −0.195029505 
                 0.195029505 
               
               
                 CARD11 
                 0.086571436 
                 0.038937688 
                 0.320536975 
                 −0.195027852 
                 0.195027852 
               
               
                 NUP205 
                 0.007000286 
                 0.043720156 
                 0.244397563 
                 −0.193677121 
                 0.193677121 
               
               
                 COX5A 
                 0.001266714 
                 0.073535125 
                 0.267407969 
                 −0.192606129 
                 0.192606129 
               
               
                 IL12RB2 
                 0.116243957 
                 0.168973447 
                 0.475805088 
                 −0.190587683 
                 0.190587683 
               
               
                 ITGB2 
                 −0.092971857 
                 0.032449906 
                 0.128161219 
                 −0.18868317 
                 0.18868317 
               
               
                 FXYD6 
                 −0.132427886  
                 −0.032194075 
                 0.020960069 
                 −0.185582029 
                 0.185582029 
               
               
                 NKG7 
                 0.100092 
                 0.177019062 
                 0.091530313 
                 0.18558075 
                 0.18558075 
               
               
                 CLEC12B 
                 0.126618243  
                 −0.216706594  
                 −0.274877219 
                 0.184788868 
                 0.184788868 
               
               
                 TBX21 
                 0.147042607 
                 0.171793313 
                 0.134367281 
                 0.184468638 
                 0.184468638 
               
               
                 TMEM106C 
                 −0.072996871 
                 0.096723306 
                 0.207120563 
                 −0.183394128 
                 0.183394128 
               
               
                 EOMES 
                 0.031210564 
                 0.180122613 
                 0.028667006 
                 0.182666171 
                 0.182666171 
               
               
                 CPPED1 
                 −0.075764786  
                 −0.006007437 
                 0.097081875 
                 −0.178854098 
                 0.178854098 
               
               
                 HEPACAM2 
                 0.30810525  
                 −0.328715588 
                 0.15575645 
                 −0.176366788 
                 0.176366788 
               
               
                 BMI1 
                 −0.03228375 
                 0.041806344 
                 0.185530888 
                 −0.176008294 
                 0.176008294 
               
               
                 CST7 
                 0.042171821  
                 −0.157493094 
                 0.059774281 
                 −0.175095554 
                 0.175095554 
               
               
                 KIR2DL2 
                 0.150170293 
                 0.048071569 
                 0.023736862 
                 0.174504999 
                 0.174504999 
               
               
                 PROS1 
                 −0.141067664 
                 −0.0105115 
                 0.0210835 
                 −0.172662664 
                 0.172662664 
               
               
                 SLC28A1 
                 0.059450621 
                 0.037232388 
                 0.268637725 
                 −0.171954716 
                 0.171954716 
               
               
                 STEAP4 
                 −0.024713186  
                 −0.025752356 
                 0.119735125 
                 −0.170200667 
                 0.170200667 
               
               
                 RORA 
                 −0.005687036 
                 0.04953275 
                 0.213705344 
                 −0.169859629 
                 0.169859629 
               
               
                 MATK 
                 0.128941  
                 −0.057783469  
                 −0.097076062 
                 0.168233594 
                 0.168233594 
               
               
                 TCF7 
                 0.015533071 
                 0.119273375 
                 0.302479313 
                 −0.167672866 
                 0.167672866 
               
               
                 MCTP1 
                 −0.064457314 
                 0.02050475 
                 0.121421475 
                 −0.165374039 
                 0.165374039 
               
               
                 CCNB2 
                 0.11113635 
                 0.160589037 
                 0.106655813 
                 0.165069575 
                 0.165069575 
               
               
                 CCL5 
                 0.082592786 
                 0.179442438 
                 0.097006 
                 0.165029223 
                 0.165029223 
               
               
                 TRIP13 
                 −0.151740693 
                 0.029123638  
                 −0.287642194 
                 0.165025138 
                 0.165025138 
               
               
                 TNFSF12 
                 −0.048036679 
                 0.070770719 
                 0.186750219 
                 −0.164016179 
                 0.164016179 
               
               
                 PDGFRB 
                 0.171366921 
                 0.026544106 
                 0.034163281 
                 0.163747746 
                 0.163747746 
               
               
                 NDUFB11 
                 −0.040507464  
                 −0.013961031 
                 0.107839563 
                 −0.162308058 
                 0.162308058 
               
               
                 ELP4 
                 0.000880343 
                 0.100837619 
                 0.263235831 
                 −0.16151787 
                 0.16151787 
               
               
                 KLRC1 
                 0.000687164 
                 0.099160981 
                 0.261111831 
                 −0.161263686 
                 0.161263686 
               
               
                 PMS1 
                 0.09187805 
                 0.017723269 
                 0.269440381 
                 −0.159839063 
                 0.159839063 
               
               
                 SCPEP1 
                 −0.0993085 
                 0.080756812 
                 0.139985219 
                 −0.158536906 
                 0.158536906 
               
               
                 SP140 
                 −0.097582571 
                 0.103564562 
                 0.164278719 
                 −0.158296728 
                 0.158296728 
               
               
                 POLA1 
                 0.052668236 
                 0.040824187 
                 0.251305694 
                 −0.157813271 
                 0.157813271 
               
               
                 FASLG 
                 0.085012064 
                 0.136574256 
                 0.378932025 
                 −0.157345704 
                 0.157345704 
               
               
                 SLC35A3 
                 0.324811771 
                 0.145015194 
                 0.626809575 
                 −0.15698261 
                 0.15698261 
               
               
                 SORT1 
                 −0.009813957 
                 0.002481187 
                 0.147676013 
                 −0.155008782 
                 0.155008782 
               
               
                 ABCA8 
                 0.031660065 
                 0.053897269 
                 0.240461319 
                 −0.154903985 
                 0.154903985 
               
               
                 DTYMK 
                 −0.04659875 
                 0.132572344 
                 0.239921625 
                 −0.153948031 
                 0.153948031 
               
               
                 NOP56 
                 −0.000568964 
                 0.084934719 
                 0.237542219 
                 −0.153176464 
                 0.153176464 
               
               
                 SMARCAL1 
                 −0.086243036 
                 0.100209938 
                 0.166715688 
                 −0.152748786 
                 0.152748786 
               
               
                 PLEK 
                 0.019009071  
                 −0.065560094 
                 0.10602225 
                 −0.152573272 
                 0.152573272 
               
               
                 SEH1L 
                 0.03765995 
                 0.080064425 
                 0.269638244 
                 −0.151913869 
                 0.151913869 
               
               
                 ITK 
                 −0.015928207 
                 0.14679825 
                 0.281890887 
                 −0.151020845 
                 0.151020845 
               
               
                 NFAM1 
                 −0.027323071 
                 −0.0392185 
                 0.084381437 
                 −0.150923009 
                 0.150923009 
               
               
                 ITPR3 
                 0.374672979  
                 −0.044524775 
                 0.179360838 
                 0.150787366 
                 0.150787366 
               
               
                 TNFRSF18 
                 0.028010107 
                 0.041735181 
                 0.218599825 
                 −0.148854537 
                 0.148854537 
               
               
                 FCAR 
                 −0.066841164  
                 −0.027840525 
                 0.053792012 
                 −0.148473702 
                 0.148473702 
               
               
                 E2F7 
                 −0.405322936 
                 0.215555531 
                 −0.041365931 
                 −0.148401473 
                 0.148401473 
               
               
                 KCNQ1 
                 −0.048365643 
                 0.064700375 
                 0.162571312 
                 −0.14623658 
                 0.14623658 
               
               
                 CENPW 
                 −0.164889786 
                 0.230038812 
                 0.210302344 
                 −0.145153317 
                 0.145153317 
               
               
                 SIGLEC7 
                 −0.024430871  
                 −0.088715794 
                 0.031245875 
                 −0.14439254 
                 0.14439254 
               
               
                 PCNA 
                 0.035651979 
                 0.039530006 
                 0.219408269 
                 −0.144226284 
                 0.144226284 
               
               
                 ANO10 
                 −0.039469393 
                 0.011942625 
                 0.11532075 
                 −0.142847518 
                 0.142847518 
               
               
                 PTPRE 
                 −0.076416679 
                 0.046165188 
                 0.110726156 
                 −0.140977647 
                 0.140977647 
               
               
                 ABCC13 
                 0.198030307  
                 −0.048670069 
                 0.008429625 
                 0.140930613 
                 0.140930613 
               
               
                 TSNAX 
                 −0.041252929 
                 0.119107719 
                 0.215539006 
                 −0.137684216 
                 0.137684216 
               
               
                 SSBP1 
                 0.043657036 
                 0.076313656 
                 0.256911875 
                 −0.136941183 
                 0.136941183 
               
               
                 TGFBR3 
                 0.057640943 
                 0.225603875 
                 0.146874275 
                 0.136370543 
                 0.136370543 
               
               
                 CENPE 
                 0.094657979 
                 0.11519455 
                 0.345300175 
                 −0.135447646 
                 0.135447646 
               
               
                 NDUFS8 
                 −0.009986071 
                 0.024954469 
                 0.149320406 
                 −0.134352009 
                 0.134352009 
               
               
                 CARD9 
                 0.000456214  
                 −0.024868219 
                 0.109741531 
                 −0.134153536 
                 0.134153536 
               
               
                 CHAF1B 
                 0.015375293 
                 0.113135369 
                 0.260426356 
                 −0.131915695 
                 0.131915695 
               
               
                 IL6R 
                 −0.0899715 
                 0.080235  
                 −0.141129344 
                 0.131392844 
                 0.131392844 
               
               
                 CD8A 
                 0.062538893 
                 0.115027688 
                 0.307421594 
                 −0.129855013 
                 0.129855013 
               
               
                 CDCA5 
                 0.141994621 
                 0.0153348 
                 0.0285846 
                 0.128744821 
                 0.128744821 
               
               
                 CEP72 
                 0.121346421 
                 0.049939025 
                 0.299817094 
                 −0.128531647 
                 0.128531647 
               
               
                 KIAA1109 
                 −0.036829514 
                 0.057112206 
                 0.148373894 
                 −0.128091202 
                 0.128091202 
               
               
                 H2AFX 
                 0.016909343 
                 0.107348406  
                 −0.003697669 
                 0.127955418 
                 0.127955418 
               
               
                 HOPX 
                 0.112690921 
                 0.061422119 
                 0.301787156 
                 −0.127674116 
                 0.127674116 
               
               
                 ARL4C 
                 0.072803357 
                 0.103496344 
                 0.302879469 
                 −0.126579768 
                 0.126579768 
               
               
                 TLR8 
                 −0.045178079  
                 −0.045833031 
                 0.032884969 
                 −0.123896079 
                 0.123896079 
               
               
                 SLC16A3 
                 −0.165960286  
                 −0.097487344  
                 −0.140923594 
                 −0.122524036 
                 0.122524036 
               
               
                 CD96 
                 −0.016845807 
                 0.130848437 
                 0.234244275 
                 −0.120241645 
                 0.120241645 
               
               
                 FMR1 
                 −0.016440529  
                 −0.004763262 
                 0.098062581 
                 −0.119266372 
                 0.119266372 
               
               
                 CAMK4 
                 0.17398735  
                 −0.051962625 
                 0.241167213 
                 −0.119142488 
                 0.119142488 
               
               
                 CENPF 
                 0.071971921  
                 −0.075413106 
                 0.115432769 
                 −0.118873954 
                 0.118873954 
               
               
                 ANP32E 
                 −0.073683321 
                 0.110316563 
                 0.1554933 
                 −0.118860059 
                 0.118860059 
               
               
                 LCK 
                 0.079214964 
                 0.091696875 
                 0.287152063 
                 −0.116240223 
                 0.116240223 
               
               
                 KCTD12 
                 −0.10831425  
                 −0.100223344  
                 −0.093382125 
                 −0.115155469 
                 0.115155469 
               
               
                 CASC5 
                 −0.194317893 
                 0.338253019 
                 0.258946669 
                 −0.115011543 
                 0.115011543 
               
               
                 SGOL2 
                 0.218390882  
                 −0.199590273 
                 0.133709203 
                 −0.114908593 
                 0.114908593 
               
               
                 TNFRSF1B 
                 −0.074531214 
                 0.014785844 
                 0.054734187 
                 −0.114479558 
                 0.114479558 
               
               
                 GZMM 
                 0.085528179 
                 0.056466125 
                 0.027774781 
                 0.114219522 
                 0.114219522 
               
               
                 IL7R 
                 0.072157107 
                 0.148358125 
                 0.334539719 
                 −0.114024487 
                 0.114024487 
               
               
                 MCM6 
                 0.042624929 
                 0.199344263 
                 0.35289755 
                 −0.110928359 
                 0.110928359 
               
               
                 CD1D 
                 −0.013206666 
                 0.246479216 
                 0.343240125 
                 −0.109967576 
                 0.109967576 
               
               
                 ASPM 
                 −0.312100279 
                 0.056704519  
                 −0.147088063 
                 −0.108307697 
                 0.108307697 
               
               
                 PAX2 
                 0.161487071  
                 −0.055965913  
                 −0.001837237 
                 0.107358396 
                 0.107358396 
               
               
                 ZMYM2 
                 0.129444679 
                 0.026701812 
                 0.263450963 
                 −0.107304471 
                 0.107304471 
               
               
                 IL2RB 
                 0.247864286 
                 0.082890125 
                 0.22417725 
                 0.106577161 
                 0.106577161 
               
               
                 PTTG1 
                 0.098365936 
                 0.086615375 
                 0.079258663 
                 0.105722648 
                 0.105722648 
               
               
                 FANCI 
                 0.073934264 
                 0.125870263 
                 0.096870381 
                 0.102934146 
                 0.102934146 
               
               
                 PCSK6 
                 0.0278519 
                 0.096634169 
                 0.022053987 
                 0.102432081 
                 0.102432081 
               
               
                 GZMH 
                 0.072301857 
                 0.187933406 
                 0.36239375 
                 −0.102158487 
                 0.102158487 
               
               
                 SLC11A1 
                 −0.089359857  
                 −0.104323438 
                 −0.092454281 
                 −0.101229013 
                 0.101229013 
               
               
                 ETS1 
                 0.015150521 
                 0.148691106 
                 0.063176088 
                 0.10066554 
                 0.10066554 
               
               
                 CKAP5 
                 0.047345043 
                 0.056420319 
                 0.203781756 
                 −0.100016395 
                 0.100016395 
               
               
                 WDFY3 
                 −0.003150579 
                 0.035841919 
                 0.132396669 
                 −0.099705329 
                 0.099705329 
               
               
                 IL18R1 
                 0.052565443 
                 0.131353344 
                 0.282953375 
                 −0.099034588 
                 0.099034588 
               
               
                 HAVCR2 
                 −0.009178479 
                 0.108920556 
                 0.194893488 
                 −0.09515141 
                 0.09515141 
               
               
                 SH3BGRL2 
                 −0.050841007 
                 0.158029269 
                 0.201938813 
                 −0.094750551  
                 0.094750551 
               
               
                 CENPN 
                 −0.16359285 
                 0.087772819 
                 0.017766275 
                 −0.093586306  
                 0.093586306 
               
               
                 ATF2 
                 0.010376893 
                 0.0675732 
                 0.170737869 
                 −0.092787776  
                 0.092787776 
               
               
                 EXOC1 
                 0.294340857 
                 0.212963188 
                 0.414737406 
                 0.092566638 
                 0.092566638 
               
               
                 KIR2DS3 
                 0.170303736  
                 −0.057887187 
                 0.204776925 
                 −0.092360377  
                 0.092360377 
               
               
                 TUBG1 
                 0.1275628 
                 0.057753981 
                 0.094358969 
                 0.090957812 
                 0.090957812 
               
               
                 NUF2 
                 0.079239486 
                 0.052017034 
                 0.220492578 
                 −0.089236059  
                 0.089236059 
               
               
                 SMC4 
                 −0.049519036 
                 0.068988038 
                 0.106945031 
                 −0.087476029  
                 0.087476029 
               
               
                 NUSAP1 
                 −0.207199657 
                 0.195487413 
                 0.07446825 
                 −0.086180495  
                 0.086180495 
               
               
                 CHST15 
                 0.035716286  
                 −0.081956625 
                 0.03941675 
                 −0.085657089  
                 0.085657089 
               
               
                 PTPN4 
                 0.183461529 
                 0.179189413 
                 0.277530538 
                 0.085120404 
                 0.085120404 
               
               
                 TACC3 
                 −0.083857321 
                 0.0461285 
                 0.044973144 
                 −0.082701965  
                 0.082701965 
               
               
                 FGD4 
                 −0.131588607 
                 0.087883312 
                 0.03755975 
                 −0.081265045  
                 0.081265045 
               
               
                 PLXND1 
                 −0.0189865 
                 0.11060225 
                 0.171687562 
                 −0.080071813  
                 0.080071813 
               
               
                 FCGR2A 
                 −0.032769571  
                 −0.020548844 
                 0.025650156 
                 −0.078968571  
                 0.078968571 
               
               
                 CCR7 
                 0.115547179 
                 0.108481656 
                 0.145899094 
                 0.078129741 
                 0.078129741 
               
               
                 FANCD2 
                 0.037001443 
                 0.003119969 
                 0.117773888 
                 −0.077652476  
                 0.077652476 
               
               
                 S1PR5 
                 0.087563907 
                 0.209525425 
                 0.221772069 
                 0.075317263 
                 0.075317263 
               
               
                 HMBS 
                 0.231740036  
                 −0.055886406 
                 0.101409062 
                 0.074444567 
                 0.074444567 
               
               
                 UBE2S 
                 0.01034575 
                 0.041629813  
                 −0.020495281 
                 0.072470844 
                 0.072470844 
               
               
                 CD247 
                 0.114385179 
                 0.142090938 
                 0.18457025 
                 0.071905866 
                 0.071905866 
               
               
                 FOXM1 
                 0.204105021  
                 −0.232078488  
                 −0.098508462 
                 0.070534996 
                 0.070534996 
               
               
                 NUP155 
                 0.144700671  
                 −0.031175944 
                 0.182827806 
                 −0.069303079  
                 0.069303079 
               
               
                 CD7 
                 0.012400536  
                 −0.038204844 
                 −0.093956906 
                 0.068152598 
                 0.068152598 
               
               
                 RAB32 
                 −0.064779993 
                 0.057404756 
                 0.060534719 
                 −0.067909955  
                 0.067909955 
               
               
                 PLEKHF1 
                 0.147747779 
                 0.083882938 
                 0.164267781 
                 0.067362935 
                 0.067362935 
               
               
                 EXO1 
                 0.12917555  
                 −0.015257425 
                 0.178355519 
                 −0.064437394  
                 0.064437394 
               
               
                 NNMT 
                 0.233886154  
                 −0.064754751 
                 0.233446688 
                 −0.064315284  
                 0.064315284 
               
               
                 CTSW 
                 0.086388214 
                 0.086623606 
                 0.109152531 
                 0.063859289 
                 0.063859289 
               
               
                 TNFSF13 
                 −0.104992364 
                 0.204233313 
                 0.162872469 
                 −0.063631521  
                 0.063631521 
               
               
                 SKA1 
                 0.172363579  
                 −0.101240878 
                 0.007584162 
                 0.063538538 
                 0.063538538 
               
               
                 TXK 
                 0.167692714 
                 0.13788895 
                 0.24493265 
                 0.060649014 
                 0.060649014 
               
               
                 CDCA2 
                 0.131150257 
                 0.08530005 
                 0.276015065 
                 −0.059564758  
                 0.059564758 
               
               
                 DHFR 
                 0.0808114  
                 −0.078742712 
                 0.061597675 
                 −0.059528988  
                 0.059528988 
               
               
                 MCM4 
                 0.310664586  
                 −0.021865731 
                 0.229669113 
                 0.059129742 
                 0.059129742 
               
               
                 NPL 
                 −0.028528464 
                 0.0650085  
                 −0.022373125 
                 0.058853161 
                 0.058853161 
               
               
                 PRC1 
                 −0.00396665 
                 −0.0044553  
                 −0.066523444 
                 0.058101494 
                 0.058101494 
               
               
                 ATIC 
                 0.18636285 
                 0.088420625 
                 0.217445369 
                 0.057338106 
                 0.057338106 
               
               
                 AFF2 
                 −0.089054274  
                 −0.124852861 
                 −0.271109782 
                 0.057202648 
                 0.057202648 
               
               
                 SLA2 
                 −0.007006543 
                 0.103122831 
                 0.152447188 
                 −0.056330899  
                 0.056330899 
               
               
                 SH2D2A 
                 0.053755679 
                 0.084245688 
                 0.081803031 
                 0.056198335 
                 0.056198335 
               
               
                 NCAPD3 
                 0.15018295 
                 0.019467175 
                 0.113947944 
                 0.055702181 
                 0.055702181 
               
               
                 GPR114 
                 0.048830007 
                 0.178102206 
                 0.172434275 
                 0.054497938 
                 0.054497938 
               
               
                 DPP4 
                 0.010671021 
                 0.171490388 
                 0.235689063 
                 −0.053527654  
                 0.053527654 
               
               
                 LAT 
                 −0.009395143 
                 0.149325594 
                 0.191682219 
                 −0.051751768 
                 0.051751768 
               
               
                 CLINT1 
                 0.024371071 
                 0.09246525 
                 0.16695325 
                 −0.050116929 
                 0.050116929 
               
               
                 SPOCK2 
                 0.0540895 
                 0.116730031 
                 0.220384125 
                 −0.049564594 
                 0.049564594 
               
               
                 TIGIT 
                 −0.002881429 
                 0.110435856 
                 0.154252106 
                 −0.046697679 
                 0.046697679 
               
               
                 CXCR3 
                 0.054416679 
                 0.173273125 
                 0.181010313 
                 0.046679491 
                 0.046679491 
               
               
                 CYBRD1 
                 0.040529114  
                 −0.119726244 
                 −0.03273975 
                 −0.046457379 
                 0.046457379 
               
               
                 TMEM71 
                 0.093268964  
                 −0.009283281 
                 0.130187875 
                 −0.046202192 
                 0.046202192 
               
               
                 MCM5 
                 0.015791714  
                 −0.022235375 
                 0.038842312 
                 −0.045285973 
                 0.045285973 
               
               
                 TCHP 
                 0.03122065 
                 0.102604531 
                 0.17764235 
                 −0.043817169 
                 0.043817169 
               
               
                 SIRT1 
                 0.072246879 
                 0.282646475 
                 0.396445619 
                 −0.041552265 
                 0.041552265 
               
               
                 ECM2 
                 0.06183995  
                 −0.034499769  
                 −0.013579256 
                 0.040919438 
                 0.040919438 
               
               
                 NACC2 
                 −0.040991 
                 0.051050375 
                 0.050223031 
                 −0.040163656 
                 0.040163656 
               
               
                 CD5 
                 0.013059036 
                 0.051298562 
                 0.101524563 
                 −0.037166964 
                 0.037166964 
               
               
                 PBX1 
                 −0.146203364 
                 0.1381656  
                 −0.044659887 
                 0.036622123 
                 0.036622123 
               
               
                 MPEG1 
                 0.228906821 
                 0.122075031 
                 0.317887406 
                 0.033094446 
                 0.033094446 
               
               
                 STMN1 
                 0.152387964 
                 0.054988531 
                 0.175320975 
                 0.032055521 
                 0.032055521 
               
               
                 SLAMF7 
                 0.09940525 
                 0.078786469 
                 0.208776125 
                 −0.030584406 
                 0.030584406 
               
               
                 CLEC4E 
                 0.03307095 
                 0.250178863 
                 0.253125025 
                 0.030124787 
                 0.030124787 
               
               
                 ITGAX 
                 −0.003191536 
                 0.03580425 
                 0.058384406 
                 −0.025771692 
                 0.025771692 
               
               
                 UBASH3A 
                 0.078104014 
                 0.0524895 
                 0.155564163 
                 −0.024970648 
                 0.024970648 
               
               
                 TTC7B 
                 −0.042112171 
                 0.233417081 
                 0.167371531 
                 0.023933379 
                 0.023933379 
               
               
                 SPAG5 
                 0.113789793 
                 0.087098931 
                 0.177345094 
                 0.02354363 
                 0.02354363 
               
               
                 IL21R 
                 0.074056021 
                 0.027803787 
                 0.120988831 
                 −0.019129022 
                 0.019129022 
               
               
                 GNLY 
                 0.021276571 
                 0.16815425 
                 0.205857406 
                 −0.016426585 
                 0.016426585 
               
               
                 PRKCQ 
                 0.009845486 
                 0.135340319 
                 0.161210463 
                 −0.016024658 
                 0.016024658 
               
               
                 KIF23 
                 −0.096498793 
                 0.083153288  
                 −0.028673256 
                 0.015327751 
                 0.015327751 
               
               
                 NDUFA3 
                 0.079680821 
                 0.028160906 
                 0.0970595 
                 0.010782228 
                 0.010782228 
               
               
                 F13A1 
                 −0.047338571 
                 0.205989906 
                 0.148638469 
                 0.010012866 
                 0.010012866 
               
               
                 SAMD3 
                 0.161056436 
                 0.096928381 
                 0.266791975 
                 −0.008807158 
                 0.008807158 
               
               
                 IKZF1 
                 0.065568071 
                 0.061111063 
                 0.133848906 
                 −0.007169772 
                 0.007169772 
               
               
                 RARRES3 
                 0.097648143 
                 0.035314469 
                 0.128298781 
                 0.00466383 
                 0.00466383 
               
               
                 GZMB 
                 0.0733865 
                 0.237917812 
                 0.315513938 
                 −0.004209625 
                 0.004209625 
               
               
                 EZH2 
                 0.039164079 
                 0.015619287 
                 0.055791712 
                 −0.001008346 
                 0.001008346 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 18 
               
             
            
               
                   
               
               
                 Subset of select genes identified from analyses 
               
               
                 of both nsclc and prostate vaccine trials 
               
            
           
           
               
               
               
               
            
               
                   
                 Week5_0  
                 Week5_0  
                   
               
               
                   
                 GE difference_ 
                 GE difference_ 
                 absolute value 
               
               
                 Gene 
                 mean_pat_ 
                 mean_pat_ 
                 ((armA +  
               
               
                 symbol 
                 clust1 
                 clust2 
                 armB) − armC) 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 LY96 
                 0.25291329 
                 −0.1675694 
                 1.58350163 
               
               
                 FIGNL1 
                 −0.3911252 
                 0.07060053 
                 1.51913289 
               
               
                 S100A8 
                 0.18004029 
                 −0.0733939  
                 1.48804251 
               
               
                 NLRC3 
                 −0.3230981 
                 0.37479546  
                 1.07067518 
               
               
                 TFEC 
                 0.14296664 
                 −0.1936751  
                 1.04488016 
               
               
                 LGALS2 
                 0.18320086 
                 −0.1859234  
                 1.04313253 
               
               
                 MSH6 
                 −0.0601969 
                 0.1064115  
                 1.02069311 
               
               
                 TARP 
                 −0.3253611 
                 0.43529539  
                 1.01652167 
               
               
                 MND1 
                 −0.239129 
                 0.51650061  
                 0.98368258 
               
               
                 S100A12 
                 0.30924814 
                 −0.0672138  
                 0.96499638 
               
               
                 PKMYT1 
                 −0.1016927 
                 0.14326432  
                 0.95541437 
               
               
                 PTAFR 
                 0.36795829 
                 −0.0962296  
                 0.94861238 
               
               
                 VSTM1 
                 0.22415614 
                 −0.292179  
                 0.93720138 
               
               
                 SAMHD1 
                 −0.0260325 
                 −0.0103238  
                 0.93471187 
               
               
                 APCDD1 
                 0.5716404 
                 −0.0894154 
                 0.8909871 
               
               
                 TLR7 
                 0.25222707 
                 −0.0928586 
                 0.8760098 
               
               
                 HNMT 
                 0.23255914 
                 −0.3267737  
                 0.86173031 
               
               
                 MS4A4A 
                 0.33475521 
                 −0.0776784  
                 0.86062401 
               
               
                 TMEM55A 
                 0.1876985 
                 −0.1285677  
                 0.86033805 
               
               
                 SHCBP1 
                 −0.1809977 
                 0.24105691  
                 0.84665962 
               
               
                 CD302 
                 0.11256429 
                 −0.2404618  
                 0.83474207 
               
               
                 RHOU 
                 0.091684 
                 −0.1374971 
                 0.7937765 
               
               
                 S100A9 
                 0.21517871 
                 −0.0338974  
                 0.78164444 
               
               
                 FAM198B 
                 0.39951821 
                 −0.1879804 
                 0.7794542 
               
               
                 ST3GAL6 
                 0.454685 
                 −0.2018707  
                 0.77259787 
               
               
                 CLEC12A 
                 0.20369814 
                 −0.2397915  
                 0.76910189 
               
               
                 GCA 
                 0.30900964 
                 0.01764846  
                 0.76216544 
               
               
                 VNN2 
                 0.23874529 
                 −0.0709664 
                 0.7599928 
               
               
                 DUSP6 
                 0.40522829 
                 −0.0708414  
                 0.75296315 
               
               
                 TLR4 
                 0.283682 
                 −0.2026975  
                 0.74434058 
               
               
                 LRRK2 
                 0.17933043 
                 −0.2534506  
                 0.74247567 
               
               
                 SLC46A2 
                 0.24682399 
                 −0.0911593  
                 0.74044915 
               
               
                 AIF1 
                 0.11872371 
                 −0.1827316  
                 0.73405135 
               
               
                 HK3 
                 0.23748971 
                 −0.0914472  
                 0.73353891 
               
               
                 VNN1 
                 0.24903221 
                 −0.1813005  
                 0.70725902 
               
               
                 PID1 
                 0.16359979 
                 −0.1714977  
                 0.69739934 
               
               
                 MAD2L1 
                 −0.1968512 
                 0.22556866  
                 0.69333102 
               
               
                 GZMK 
                 −0.2942172 
                 0.25558446  
                 0.68574867 
               
               
                 CYP1B1 
                 0.32722971 
                 −0.2386703  
                 0.67912606 
               
               
                 MYBL2 
                 −0.2431724 
                 0.17455584  
                 0.67911383 
               
               
                 IFI30 
                 0.144974 
                 −0.0960316  
                 0.67847906 
               
               
                 ICOS 
                 −0.1726607 
                 0.33378096  
                 0.67724611 
               
               
                 CD28 
                 −0.2150971 
                 0.15756741  
                 0.66959981 
               
               
                 SGK1 
                 0.31619786 
                 −0.4520401  
                 0.66743042 
               
               
                 PLA2G7 
                 0.15559636 
                 −0.1837311  
                 0.66175112 
               
               
                 RMI1 
                 0.22933837 
                 0.23179671  
                 0.65674569 
               
               
                 CCR2 
                 0.4050525 
                 0.14351464  
                 0.64420269 
               
               
                 FCN1 
                 0.14812457 
                 −0.1072711 
                 0.6428825 
               
               
                 ZWINT 
                 −0.2281671 
                 0.37430662 
                 0.642228 
               
               
                 AMICA1 
                 0.22741957 
                 −0.141412  
                 0.63861782 
               
               
                 CLEC7A 
                 0.17440871 
                 −0.3200379  
                 0.63849294 
               
               
                 MSH2 
                 −0.117764 
                 0.31093821 
                 0.6337839 
               
               
                 MFSD1 
                 0.1568815 
                 −0.1414731  
                 0.62313049 
               
               
                 KCNJ2 
                 0.53597566 
                 0.22722416  
                 0.62294673 
               
               
                 IFNG 
                 −0.4260917 
                 0.47086009  
                 0.61901225 
               
               
                 CSTA 
                 0.15835021 
                 −0.2113985  
                 0.61435129 
               
               
                 MYBL1 
                 −0.3237831 
                 0.35550657  
                 0.61394992 
               
               
                 MNDA 
                 0.30412057 
                 −0.1542547  
                 0.61266539 
               
               
                 RBP7 
                 0.23331714 
                 −0.3036785  
                 0.61070353 
               
               
                 BST1 
                 0.122712 
                 −0.186492  
                 0.60604323 
               
               
                 DLGAP5 
                 −0.4315828 
                 0.63624947  
                 0.60031925 
               
               
                 NOD2 
                 0.17425829 
                 −0.1454336  
                 0.59975323 
               
               
                 LILRA3 
                 0.20059286 
                 −0.1835364  
                 0.59341604 
               
               
                 CLEC4A 
                 0.18052064 
                 −0.1931263  
                 0.59074397 
               
               
                 TNFSF13B 
                 0.10512379 
                 −0.1354275  
                 0.58924638 
               
               
                 CSF2RA 
                 0.2099765 
                 −0.1568839  
                 0.58905845 
               
               
                 BRI3 
                 0.15394743 
                 −0.1632444  
                 0.58755564 
               
               
                 LMO2 
                 0.31630214 
                 −0.0804872  
                 0.57990754 
               
               
                 KIAA0101 
                 −0.4763506 
                 0.48525963  
                 0.57873232 
               
               
                 RFC5 
                 −0.0564904 
                 0.16896686  
                 0.57734968 
               
               
                 FEN1 
                 −0.1104692 
                 0.29375101  
                 0.57678051 
               
               
                 PTPN22 
                 −0.1079056 
                 0.10260764  
                 0.57319577 
               
               
                 CDKN3 
                 −0.2396239 
                 0.37401346  
                 0.57222471 
               
               
                 QPCT 
                 0.17933 
                 −0.139771  
                 0.56171375 
               
               
                 NDC80 
                 −0.2696579 
                 0.34558996  
                 0.55789998 
               
               
                 KIR2DS2 
                 −0.512763 
                 0.28105043  
                 0.55592571 
               
               
                 FPR1 
                 0.15585371 
                 −0.1152266  
                 0.55319134 
               
               
                 ENPP5 
                 −0.1980916 
                 0.55005255  
                 0.54716296 
               
               
                 DPYD 
                 0.15686936 
                 −0.138058  
                 0.54407704 
               
               
                 TGFBI 
                 0.21844536 
                 −0.2026333  
                 0.54289146 
               
               
                 CDT1 
                 −0.3920278 
                 0.50043445 
                 0.5284931 
               
               
                 KLRB1 
                 −0.3829834 
                 0.23405564  
                 0.52746592 
               
               
                 SMC2 
                 −0.1223013 
                 0.18895004  
                 0.52373434 
               
               
                 TYROBP 
                 0.12911129 
                 −0.1495625  
                 0.52248479 
               
               
                 GMNN 
                 −0.1206991 
                 0.18704521  
                 0.52038427 
               
               
                 FGR 
                 0.13959557 
                 −0.137834  
                 0.51922646 
               
               
                 KIF18A 
                 −0.4757864 
                 0.79021046  
                 0.51609086 
               
               
                 KIF20B 
                 0.01059714 
                 0.04736749  
                 0.51442842 
               
               
                 RAD21 
                 −0.1034677 
                 0.16341486  
                 0.51255661 
               
               
                 SLC31A2 
                 0.20108021 
                 −0.0789601  
                 0.51054162 
               
               
                 VNN3 
                 0.08985123 
                 −0.3932456  
                 0.50444625 
               
               
                 MARCO 
                 0.262151 
                 −0.0732073  
                 0.49729851 
               
               
                 KIF20A 
                 −0.2128 
                 0.41019729  
                 0.49036135 
               
               
                 RAB31 
                 0.19826943 
                 −0.196555  
                 0.48769562 
               
               
                 TMEM154 
                 0.07131207 
                 −0.1459213  
                 0.48489437 
               
               
                 TLR1 
                 0.216556 
                 −0.0681997  
                 0.48466685 
               
               
                 CD14 
                 0.20628029 
                 −0.1083709  
                 0.48328154 
               
               
                 SPC25 
                 −0.3826298 
                 0.44521026  
                 0.47795474 
               
               
                 ASGR1 
                 0.3071775 
                 −0.2405057  
                 0.47638281 
               
               
                 EVI5 
                 0.304583 
                 −0.3472783  
                 0.47583407 
               
               
                 TLR6 
                 0.32942427 
                 −0.1833656 
                 0.4719326 
               
               
                 EMILIN2 
                 0.132286 
                 −0.1315948 
                 0.4710352 
               
               
                 CCNB1 
                 −0.2205839 
                 0.48166149  
                 0.46412741 
               
               
                 RNASE2 
                 0.27261479 
                 −0.0458946  
                 0.46154366 
               
               
                 CTSH 
                 0.08030629 
                 −0.1606683  
                 0.46063525 
               
               
                 S1PR3 
                 0.39169693 
                 −0.1508594  
                 0.45997762 
               
               
                 IL1RN 
                 0.27895086 
                 −0.0517496 
                 0.4594155 
               
               
                 CEP55 
                 −0.2470836 
                 0.61351535  
                 0.45922553 
               
               
                 ECT2 
                 0.09959477 
                 0.08800196  
                 0.45700016 
               
               
                 AQP9 
                 0.45163329 
                 −0.1484292 
                 0.4557785 
               
               
                 FES 
                 0.20222443 
                 −0.1063407  
                 0.45417507 
               
               
                 RNF130 
                 0.1476985 
                 −0.1675974  
                 0.45272824 
               
               
                 PADI2 
                 0.24145129 
                 −0.273758  
                 0.44702759 
               
               
                 TPX2 
                 −0.1368961 
                 0.39044902  
                 0.44619335 
               
               
                 NEK2 
                 −0.4797225 
                 0.28285472  
                 0.44548517 
               
               
                 CSF1R 
                 0.11002936 
                 −0.2353389  
                 0.43745163 
               
               
                 RPA3 
                 −0.0468167 
                 0.20367254  
                 0.43511192 
               
               
                 SMARCD3 
                 0.171004 
                 −0.2364289  
                 0.43270195 
               
               
                 GPR56 
                 −0.3941556 
                 0.42937814  
                 0.42807517 
               
               
                 MGST1 
                 0.26013621 
                 −0.171845  
                 0.42270199 
               
               
                 FCGR1B 
                 0.32184743 
                 0.123407  
                 0.42115805 
               
               
                 KCNE3 
                 0.28663807 
                 −0.1760301  
                 0.42090032 
               
               
                 MS4A6A 
                 0.21972471 
                 −0.1876675  
                 0.41792249 
               
               
                 SIRPB1 
                 0.12962343 
                 −0.1614806  
                 0.41581475 
               
               
                 RAD51 
                 −0.3247114 
                 0.60031006  
                 0.41531994 
               
               
                 PLBD1 
                 0.30856714 
                 −0.1336086  
                 0.41497238 
               
               
                 LAT2 
                 0.14575757 
                 −0.0962826  
                 0.41366954 
               
               
                 LILRB3 
                 0.21902857 
                 −0.1867784  
                 0.41348304 
               
               
                 LILRA5 
                 0.11851443 
                 −0.224764  
                 0.41331521 
               
               
                 PRIM1 
                 −0.0595427 
                 0.19627593  
                 0.41238984 
               
               
                 CFD 
                 0.09556486 
                 −0.3024731  
                 0.41180017 
               
               
                 NCF2 
                 0.17595029 
                 −0.1856544  
                 0.41128375 
               
               
                 AGTRAP 
                 0.17473921 
                 −0.1716012  
                 0.41016699 
               
               
                 GIMAP7 
                 0.03605657 
                 0.41435014  
                 0.40999757 
               
               
                 IRAK3 
                 0.17726571 
                 −0.3114963  
                 0.40814394 
               
               
                 ASGR2 
                 0.39454371 
                 −0.2091958  
                 0.40774017 
               
               
                 CD36 
                 0.308184 
                 −0.1079273  
                 0.40726658 
               
               
                 CD33 
                 0.155254 
                 −0.2266752 
                 0.4065399 
               
               
                 PSAP 
                 0.12162514 
                 −0.20859  
                 0.40558285 
               
               
                 BCL6 
                 0.2903715 
                 −0.2510326  
                 0.40459452 
               
               
                 LILRA6 
                 0.20520129 
                 −0.075644  
                 0.40169221 
               
               
                 ACSL1 
                 0.16061336 
                 −0.2069103  
                 0.40051088 
               
               
                 SULF2 
                 0.15370471 
                 −0.2286793  
                 0.39936672 
               
               
                 CRTAM 
                 0.05142471 
                 0.16918629  
                 0.39889111 
               
               
                 GZMA 
                 −0.3233462 
                 0.44860282  
                 0.39138932 
               
               
                 PGD 
                 0.23078686 
                 −0.0989967 
                 0.3894255 
               
               
                 RFC4 
                 −0.0840019 
                 0.28309346  
                 0.38924309 
               
               
                 POLD3 
                 0.14601436 
                 0.08214118  
                 0.38879764 
               
               
                 MYD88 
                 0.127095 
                 −0.0450128  
                 0.38007042 
               
               
                 SH2D1A 
                 −0.2182584 
                 0.37141254 
                 0.3795095 
               
               
                 NCF1 
                 0.18834164 
                 −0.0888491 
                 0.3792863 
               
               
                 CD27 
                 −0.1918529 
                 0.347574  
                 0.37901562 
               
               
                 HPSE 
                 0.27726671 
                 −0.1332741  
                 0.37703943 
               
               
                 UBE2T 
                 −0.1152586 
                 0.50473483  
                 0.37528116 
               
               
                 LILRA2 
                 0.08333786 
                 −0.1941418 
                 0.3730587 
               
               
                 LEF1 
                 −0.2306776 
                 0.27287407  
                 0.37274953 
               
               
                 KNTC1 
                 −0.0373946 
                 0.17103619  
                 0.37144283 
               
               
                 ACPP 
                 0.33864257 
                 −0.2515963  
                 0.36989708 
               
               
                 SLC7A7 
                 0.15972557 
                 −0.2263817  
                 0.36773981 
               
               
                 FGFBP2 
                 −0.5226531 
                 0.47477268  
                 0.36717029 
               
               
                 TMPO 
                 −0.008721 
                 0.06823154  
                 0.36509451 
               
               
                 CEP76 
                 −0.0563533 
                 0.22814923  
                 0.36508591 
               
               
                 CPVL 
                 0.19077136 
                 −0.265568  
                 0.36420488 
               
               
                 TYMS 
                 −0.437593 
                 0.48260443  
                 0.36281913 
               
               
                 CDC25A 
                 −0.2446423 
                 0.09325778  
                 0.36107204 
               
               
                 CKS1B 
                 −0.1774076 
                 0.07276836  
                 0.36086393 
               
               
                 GPR171 
                 0.04673821 
                 0.44807932  
                 0.35950488 
               
               
                 POLA2 
                 −0.01999 
                 0.14915151  
                 0.35765998 
               
               
                 RAN 
                 −0.0533419 
                 0.12015604  
                 0.35633478 
               
               
                 F5 
                 0.25060213 
                 −0.0436135  
                 0.35561866 
               
               
                 CD2 
                 −0.2164654 
                 0.38027496  
                 0.35558297 
               
               
                 NDUFA8 
                 −0.0209871 
                 0.11569321  
                 0.35526445 
               
               
                 RBM47 
                 0.34911643 
                 −0.2308224  
                 0.35463086 
               
               
                 CST3 
                 0.08667 
                 −0.2032598  
                 0.35391682 
               
               
                 SKA3 
                 −0.3279785 
                 0.82917226  
                 0.35208682 
               
               
                 SLAMF1 
                 −0.0525696 
                 0.33766054  
                 0.34173976 
               
               
                 NUP88 
                 −0.0518056 
                 0.11604057  
                 0.34158759 
               
               
                 BRCA1 
                 0.1411805 
                 0.19119731  
                 0.33554829 
               
               
                 CYFIP1 
                 0.27867043 
                 −0.1617847  
                 0.33478346 
               
               
                 TIPIN 
                 −0.073668 
                 0.12286243  
                 0.33322639 
               
               
                 LILRB2 
                 0.10856657 
                 −0.1524331  
                 0.33233354 
               
               
                 IL13RA1 
                 0.22220743 
                 −0.3724449  
                 0.33149446 
               
               
                 NCF4 
                 0.28713014 
                 −0.1936098  
                 0.33002888 
               
               
                 LTBR 
                 0.14341086 
                 −0.2142621  
                 0.32847292 
               
               
                 ALOX5 
                 0.18758043 
                 −0.1371492  
                 0.32702454 
               
               
                 CRISPLD2 
                 0.32555891 
                 −0.3586666  
                 0.32526073 
               
               
                 PYGL 
                 0.29134307 
                 −0.2516874  
                 0.32473667 
               
               
                 CFP 
                 0.12887729 
                 −0.2008422  
                 0.32390272 
               
               
                 KIF2C 
                 −0.1844746 
                 0.36618417  
                 0.32227884 
               
               
                 HCK 
                 0.145662 
                 −0.1101782  
                 0.32224187 
               
               
                 THEMIS 
                 −0.1614729 
                 0.303302 
                 0.3212733 
               
               
                 KIAA1598 
                 0.19605307 
                 −0.2428218  
                 0.32116134 
               
               
                 TIMP2 
                 0.21143257 
                 −0.1767553  
                 0.31745221 
               
               
                 GATA3 
                 −0.1580016 
                 0.27439999  
                 0.31631603 
               
               
                 NLRP3 
                 0.19856679 
                 −0.4459587  
                 0.31478029 
               
               
                 UHRF1 
                 −0.2013698 
                 0.38829452  
                 0.31378424 
               
               
                 OIP5 
                 −0.2158287 
                 0.49771236  
                 0.31289566 
               
               
                 PAK1 
                 0.11821371 
                 −0.076532  
                 0.31270228 
               
               
                 LY86 
                 0.17209671 
                 −0.2437504  
                 0.31243225 
               
               
                 KLRD1 
                 −0.3996624 
                 0.33700039  
                 0.31219778 
               
               
                 DTL 
                 −0.320412 
                 0.56387945  
                 0.31180503 
               
               
                 SIRPA 
                 0.30036914 
                 −0.1727997  
                 0.31140539 
               
               
                 TRAT1 
                 −0.1332071 
                 0.33377432  
                 0.31091869 
               
               
                 RASSF4 
                 0.12517986 
                 −0.1642181  
                 0.30897904 
               
               
                 PECAM1 
                 0.16631493 
                 −0.2334685  
                 0.30897622 
               
               
                 BUB1 
                 −0.2520322 
                 0.5736033  
                 0.30764568 
               
               
                 PYCARD 
                 0.121423 
                 −0.0958546  
                 0.30668021 
               
               
                 ARHGEF10L 
                 0.14063229 
                 −0.211631  
                 0.30492673 
               
               
                 ITM2A 
                 −0.2660534 
                 0.35634646 
                 0.3044698 
               
               
                 LILRB1 
                 0.24377036 
                 −0.0943035 
                 0.3020182 
               
               
                 GIMAP6 
                 0.00075014 
                 0.19616636  
                 0.30120438 
               
               
                 RASGRP1 
                 −0.2903379 
                 0.30770064  
                 0.29981424 
               
               
                 AGPAT9 
                 0.15172171 
                 −0.0584703  
                 0.29872519 
               
               
                 FPR2 
                 0.28376686 
                 −0.063922  
                 0.29368903 
               
               
                 AURKB 
                 −0.3572037 
                 0.00276418  
                 0.29357518 
               
               
                 IMPA2 
                 0.30031436 
                 −0.1785237  
                 0.28937466 
               
               
                 CSF3R 
                 0.31417671 
                 −0.245967  
                 0.28290744 
               
               
                 PVRIG 
                 −0.3300437 
                 0.43754479  
                 0.28229247 
               
               
                 RAD54L 
                 −0.1882477 
                 0.31971504  
                 0.27966512 
               
               
                 ATP9A 
                 −0.1948771 
                 0.29154147  
                 0.27858758 
               
               
                 HOMER3 
                 0.26818543 
                 −0.2048115  
                 0.27512564 
               
               
                 TNS3 
                 0.27859793 
                 −0.1568785  
                 0.27421914 
               
               
                 NLRP12 
                 0.22441814 
                 −0.1575549  
                 0.27378834 
               
               
                 ADRB2 
                 0.04538143 
                 0.21887268  
                 0.27331231 
               
               
                 TLR2 
                 0.44489771 
                 −0.1334344  
                 0.26995822 
               
               
                 SERPINA1 
                 0.18943 
                 −0.1430217  
                 0.26783199 
               
               
                 SLC24A4 
                 0.19907907 
                 −0.2257899  
                 0.26620923 
               
               
                 GLT1D1 
                 0.29008614 
                 −0.1784594  
                 0.26556227 
               
               
                 KLRK1 
                 −0.2942924 
                 0.34556071  
                 0.26183928 
               
               
                 CX3CR1 
                 0.14954157 
                 0.36685596  
                 0.26072662 
               
               
                 BCL2 
                 −0.1933056 
                 0.25353029  
                 0.25863276 
               
               
                 MBOAT7 
                 0.20782507 
                 −0.1171386  
                 0.25719238 
               
               
                 KIR2DL5A 
                 −0.3670154 
                 0.33725142  
                 0.25674147 
               
               
                 MELK 
                 −0.4531195 
                 0.54402785  
                 0.25518512 
               
               
                 PLXNB2 
                 0.12047643 
                 −0.1692871  
                 0.25458228 
               
               
                 KLRF1 
                 −0.4228596 
                 0.32693082  
                 0.25236879 
               
               
                 ANLN 
                 −0.5264763 
                 0.72441581  
                 0.25196326 
               
               
                 DOK3 
                 0.18839314 
                 −0.072521  
                 0.24778586 
               
               
                 PRKCH 
                 −0.3584819 
                 0.26582529  
                 0.24681067 
               
               
                 ABLIM1 
                 −0.1923061 
                 0.3216015  
                 0.24501985 
               
               
                 EMR2 
                 0.16595464 
                 −0.2645479  
                 0.24246048 
               
               
                 P2RY13 
                 0.317733 
                 −0.1098233  
                 0.24071498 
               
               
                 KIR3DL1 
                 −0.4576109 
                 0.25522369  
                 0.23961293 
               
               
                 CD163 
                 0.28459529 
                 −0.2914575  
                 0.23826983 
               
               
                 CDCA7 
                 −0.21515 
                 0.40727161  
                 0.23802171 
               
               
                 HHEX 
                 0.21694243 
                 −0.1352445  
                 0.23658793 
               
               
                 KLRC3 
                 −0.4404443 
                 0.27508348  
                 0.23570741 
               
               
                 GINS4 
                 −0.067823 
                 0.22594522  
                 0.23400711 
               
               
                 PRAM1 
                 0.20610086 
                 −0.2093488  
                 0.23394564 
               
               
                 IFNGR2 
                 0.22150264 
                 −0.2453426  
                 0.23288102 
               
               
                 SPI1 
                 0.12291529 
                 −0.1344635  
                 0.23243227 
               
               
                 MEGF9 
                 0.229724 
                 −0.1275625  
                 0.23166605 
               
               
                 CDCA8 
                 −0.2282616 
                 0.2586116  
                 0.22982876 
               
               
                 ALDH2 
                 0.13867614 
                 −0.2825195  
                 0.22925592 
               
               
                 RNASE6 
                 0.24234229 
                 −0.2412168  
                 0.22871705 
               
               
                 STAT4 
                 −0.3668694 
                 0.33649532  
                 0.22717006 
               
               
                 SLC15A3 
                 0.14341379 
                 −0.2141991  
                 0.22675477 
               
               
                 PLK1 
                 0.4368879 
                 0.34197855 
                 0.2262495 
               
               
                 CDK1 
                 −0.2976619 
                 0.35394821  
                 0.22600548 
               
               
                 FBP1 
                 0.24521021 
                 −0.2207796 
                 0.225988 
               
               
                 CLIC3 
                 −0.4618959 
                 0.20322614  
                 0.22596421 
               
               
                 MYO1F 
                 0.13985314 
                 −0.0322897 
                 0.2224607 
               
               
                 S100A11 
                 0.17343407 
                 −0.1818736  
                 0.22134581 
               
               
                 AOAH 
                 0.11295686 
                 −0.1658184  
                 0.21938268 
               
               
                 CD3D 
                 −0.2334819 
                 0.39212054  
                 0.21866053 
               
               
                 TMTC2 
                 0.38385421 
                 −0.1644296  
                 0.21700901 
               
               
                 PTGDR 
                 −0.2460782 
                 0.42568543 
                 0.2166249 
               
               
                 TREM1 
                 0.31924157 
                 −0.3498546  
                 0.21621519 
               
               
                 FCGRT 
                 0.12817407 
                 −0.2209585  
                 0.21604277 
               
               
                 CD8B 
                 −0.1882037 
                 0.34228961  
                 0.21353166 
               
               
                 PRF1 
                 −0.3665207 
                 0.42110561 
                 0.2112278 
               
               
                 NCAM1 
                 −0.3655757 
                 0.18317471  
                 0.21062028 
               
               
                 CYBB 
                 0.11776321 
                 −0.0507948  
                 0.21060862 
               
               
                 SYK 
                 0.19662329 
                 −0.1717975  
                 0.20957884 
               
               
                 TBXAS1 
                 0.11928286 
                 −0.2289053  
                 0.20873346 
               
               
                 ZAP70 
                 −0.3733384 
                 0.35043057  
                 0.20738283 
               
               
                 HJURP 
                 −0.3412081 
                 0.49581671  
                 0.20527139 
               
               
                 PRKCD 
                 0.19511836 
                 −0.0893292 
                 0.2037058 
               
               
                 KIF11 
                 −0.1548747 
                 0.27468888 
                 0.2031195 
               
               
                 RHOH 
                 −0.2636339 
                 0.24160936  
                 0.20231186 
               
               
                 GRN 
                 0.20724414 
                 −0.120798  
                 0.20195312 
               
               
                 ITGAM 
                 0.17888443 
                 −0.0520518  
                 0.19961885 
               
               
                 XCL1 
                 −0.4685001 
                 0.17072114  
                 0.19780327 
               
               
                 BTK 
                 0.15670586 
                 −0.1421541  
                 0.19737015 
               
               
                 KIR2DS4 
                 −0.4630044 
                 0.33428446  
                 0.19658952 
               
               
                 GINS2 
                 −0.3195001 
                 0.46183131  
                 0.19502951 
               
               
                 IL12RB2 
                 −0.1031039 
                 0.19992615  
                 0.19058768 
               
               
                 FXYD6 
                 0.2127035 
                 −0.3337615  
                 0.18558203 
               
               
                 NKG7 
                 −0.4003281 
                 0.36869686  
                 0.18558075 
               
               
                 TBX21 
                 −0.3874794 
                 0.3888075  
                 0.18446864 
               
               
                 EOMES 
                 −0.1587816 
                 0.22841004  
                 0.18266617 
               
               
                 CPPED1 
                 0.13722893 
                 −0.2401733 
                 0.1788541 
               
               
                 CST7 
                 −0.4068891 
                 0.35034489  
                 0.17509555 
               
               
                 KIR2DL2 
                 −0.5014236 
                 0.33998994 
                 0.174505 
               
               
                 STEAP4 
                 0.45599867 
                 −0.0182688  
                 0.17020067 
               
               
                 RORA 
                 −0.3176324 
                 0.13335904  
                 0.16985963 
               
               
                 TCF7 
                 −0.2205655 
                 0.27400575  
                 0.16767287 
               
               
                 MCTP1 
                 0.18948886 
                 −0.2029344  
                 0.16537404 
               
               
                 CCNB2 
                 −0.1946636 
                 0.39873935  
                 0.16506957 
               
               
                 CCL5 
                 −0.3745718 
                 0.36271357  
                 0.16502922 
               
               
                 TRIP13 
                 −0.1144978 
                 0.32300382  
                 0.16502514 
               
               
                 PDGFRB 
                 −0.3998149 
                 0.51231926  
                 0.16374775 
               
               
                 KLRC1 
                 −0.4014783 
                 0.32408429  
                 0.16126369 
               
               
                 SCPEP1 
                 0.20582057 
                 −0.2124704  
                 0.15853691 
               
               
                 SP140 
                 −0.047052 
                 0.20126089  
                 0.15829673 
               
               
                 POLA1 
                 −0.0924215 
                 0.10952729  
                 0.15781327 
               
               
                 FASLG 
                 −0.4090754 
                 0.63064534 
                 0.1573457 
               
               
                 SORT1 
                 0.32733014 
                 −0.233492  
                 0.15500878 
               
               
                 DTYMK 
                 0.00880393 
                 0.07686164  
                 0.15394803 
               
               
                 SMARCAL1 
                 −0.0227714 
                 0.09328157  
                 0.15274879 
               
               
                 ITK 
                 −0.294615 
                 0.26540107  
                 0.15102084 
               
               
                 NFAM1 
                 0.14978529 
                 −0.1298816  
                 0.15092301 
               
               
                 ITPR3 
                 −0.1481427 
                 0.30532818  
                 0.15078737 
               
               
                 E2F7 
                 −0.1723229 
                 0.35509695  
                 0.14840147 
               
               
                 SIGLEC7 
                 0.12681557 
                 −0.2019304  
                 0.14439254 
               
               
                 PCNA 
                 −0.2071294 
                 0.26508754  
                 0.14422628 
               
               
                 ANO10 
                 0.183057 
                 −0.1661393  
                 0.14284752 
               
               
                 SSBP1 
                 −0.0296017 
                 0.04982696  
                 0.13694118 
               
               
                 TGFBR3 
                 −0.5264719 
                 0.3242523  
                 0.13637054 
               
               
                 CENPE 
                 −0.0645918 
                 0.27777848  
                 0.13544765 
               
               
                 CARD9 
                 0.14008593 
                 −0.2250704  
                 0.13415354 
               
               
                 CHAF1B 
                 −0.2801058 
                 0.34651381  
                 0.13191569 
               
               
                 CD8A 
                 −0.2015009 
                 0.32647193  
                 0.12985501 
               
               
                 CDCA5 
                 −0.3264995 
                 0.35916156  
                 0.12874482 
               
               
                 CEP72 
                 −0.0502172 
                 0.18587307  
                 0.12853165 
               
               
                 HOPX 
                 −0.4079511 
                 0.31981293  
                 0.12767412 
               
               
                 TLR8 
                 0.25849436 
                 −0.1439851  
                 0.12389608 
               
               
                 SLC16A3 
                 0.16651343 
                 −0.0060917  
                 0.12252404 
               
               
                 CD96 
                 −0.2954874 
                 0.27057925  
                 0.12024164 
               
               
                 CAMK4 
                 −0.2131127 
                 0.21834766  
                 0.11914249 
               
               
                 CENPF 
                 −0.2633705 
                 0.45853571  
                 0.11887395 
               
               
                 LCK 
                 −0.1946184 
                 0.24340629  
                 0.11624022 
               
               
                 KCTD12 
                 0.25632571 
                 −0.1325746  
                 0.11515547 
               
               
                 CASC5 
                 −0.0853667 
                 0.3705584  
                 0.11501154 
               
               
                 SGOL2 
                 −0.0736771 
                 0.20052546  
                 0.11490859 
               
               
                 GZMM 
                 −0.5277151 
                 0.29230996  
                 0.11421952 
               
               
                 IL7R 
                 −0.0746926 
                 0.33924354  
                 0.11402449 
               
               
                 MCM6 
                 −0.2673995 
                 0.30639182  
                 0.11092836 
               
               
                 CD1D 
                 0.33226726 
                 −0.3583073  
                 0.10996758 
               
               
                 ASPM 
                 −0.3264533 
                 0.53236356 
                 0.1083077 
               
               
                 IL2RB 
                 −0.4383737 
                 0.31879714  
                 0.10657716 
               
               
                 PTTG1 
                 −0.1689252 
                 0.35232025  
                 0.10572265 
               
               
                 FANCI 
                 −0.1670241 
                 0.21036312  
                 0.10293415 
               
               
                 GZMH 
                 −0.3635874 
                 0.43763271  
                 0.10215849 
               
               
                 SLC11A1 
                 0.25345971 
                 −0.2653527  
                 0.10122901 
               
               
                 ETS1 
                 −0.3095553 
                 0.270924  
                 0.10066554 
               
               
                 CKAP5 
                 0.06925536 
                 0.19171896  
                 0.10001639 
               
               
                 WDFY3 
                 0.227156 
                 −0.3627252  
                 0.09970533 
               
               
                 IL18R1 
                 −0.2915981 
                 0.23804614  
                 0.09903459 
               
               
                 CENPN 
                 −0.1552708 
                 −0.1012391  
                 0.09358631 
               
               
                 KIR2DS3 
                 −0.4409509 
                 0.13590208  
                 0.09236038 
               
               
                 TUBG1 
                 0.04338786 
                 0.29674596  
                 0.09095781 
               
               
                 NUF2 
                 −0.1199278 
                 0.38920616  
                 0.08923606 
               
               
                 SMC4 
                 −0.0498615 
                 0.18205457  
                 0.08747603 
               
               
                 NUSAP1 
                 −0.0788597 
                 0.11708601  
                 0.08618049 
               
               
                 CHST15 
                 0.24669143 
                 −0.1275318  
                 0.08565709 
               
               
                 PTPN4 
                 −0.3326756 
                 0.29473275 
                 0.0851204 
               
               
                 FGD4 
                 0.15304257 
                 −0.1932215  
                 0.08126504 
               
               
                 FCGR2A 
                 0.19513057 
                 −0.2171639  
                 0.07896857 
               
               
                 CCR7 
                 −0.1183211 
                 0.22720743  
                 0.07812974 
               
               
                 S1PR5 
                 −0.4823231 
                 0.27190594  
                 0.07531726 
               
               
                 CD247 
                 −0.4255066 
                 0.30918132  
                 0.07190587 
               
               
                 CD7 
                 −0.4413583 
                 0.228816 
                 0.0681526 
               
               
                 RAB32 
                 0.16056593 
                 −0.1885954  
                 0.06790996 
               
               
                 PLEKHF1 
                 −0.2791689 
                 0.33819318  
                 0.06736293 
               
               
                 EXO1 
                 −0.4247823 
                 0.59886942  
                 0.06443739 
               
               
                 CTSW 
                 −0.487019 
                 0.32969107  
                 0.06385929 
               
               
                 TNFSF13 
                 0.11867379 
                 −0.2346925  
                 0.06363152 
               
               
                 TXK 
                 −0.3989911 
                 0.28206181  
                 0.06064901 
               
               
                 CDCA2 
                 −0.3801736 
                 0.42248241  
                 0.05956476 
               
               
                 DHFR 
                 0.00870521 
                 0.28889754  
                 0.05952899 
               
               
                 MCM4 
                 −0.2320073 
                 0.36402665  
                 0.05912974 
               
               
                 NPL 
                 −0.0636007 
                 0.004466  
                 0.05885316 
               
               
                 SLA2 
                 −0.3782789 
                 0.24943868 
                 0.0563309 
               
               
                 SH2D2A 
                 −0.3770402 
                 0.36344946  
                 0.05619833 
               
               
                 NCAPD3 
                 −0.0677968 
                 0.09737246  
                 0.05570218 
               
               
                 GPR114 
                 −0.2936257 
                 0.30667602  
                 0.05449794 
               
               
                 DPP4 
                 −0.0943919 
                 0.21415932  
                 0.05352765 
               
               
                 LAT 
                 −0.2510211 
                 0.318139  
                 0.05175177 
               
               
                 SPOCK2 
                 −0.3122131 
                 0.25077596  
                 0.04956459 
               
               
                 TIGIT 
                 −0.2286996 
                 0.43677026  
                 0.04669768 
               
               
                 CXCR3 
                 −0.3350559 
                 0.40025993  
                 0.04667949 
               
               
                 CYBRD1 
                 0.111162 
                 −0.3007594  
                 0.04645738 
               
               
                 MCM5 
                 −0.0019691 
                 0.08003532  
                 0.04528597 
               
               
                 TCHP 
                 0.13509083 
                 0.20927789  
                 0.04381717 
               
               
                 NACC2 
                 0.18404114 
                 −0.26109  
                 0.04016366 
               
               
                 CD5 
                 −0.2471322 
                 0.27680911  
                 0.03716696 
               
               
                 MPEG1 
                 0.14583836 
                 −0.170232  
                 0.03309445 
               
               
                 STMN1 
                 −0.3249196 
                 0.34691546  
                 0.03205552 
               
               
                 SLAMF7 
                 −0.2300298 
                 0.34091768  
                 0.03058441 
               
               
                 CLEC4E 
                 0.2837066 
                 −0.3068958  
                 0.03012479 
               
               
                 UBASH3A 
                 −0.2202034 
                 0.35947714  
                 0.02497065 
               
               
                 SPAG5 
                 −0.0995263 
                 0.23141186  
                 0.02354363 
               
               
                 IL21R 
                 −0.1031827 
                 0.20682311  
                 0.01912902 
               
               
                 GNLY 
                 −0.4441947 
                 0.35938757  
                 0.01642658 
               
               
                 PRKCQ 
                 −0.3047643 
                 0.28771886  
                 0.01602466 
               
               
                 KIF23 
                 0.09160493 
                 0.03388473  
                 0.01532775 
               
               
                 F13A1 
                 0.28193136 
                 −0.0599006  
                 0.01001287 
               
               
                 SAMD3 
                 −0.372721 
                 0.44468854  
                 0.00880716 
               
               
                 IKZF1 
                 −0.1879529 
                 0.14708693  
                 0.00716977 
               
               
                 RARRES3 
                 −0.1910249 
                 0.15946211  
                 0.00466383 
               
               
                 GZMB 
                 −0.3850094 
                 0.24324889  
                 0.00420963 
               
               
                   
               
            
           
         
       
     
     The invention further comprises the following embodiments: 
     Embodiment 1 
     A method of determining the prognosis of a patient comprising the steps of
         (a) determining the expression level of at least one marker gene selected from the group consisting of the marker genes set out in table 1 in a sample of the patient to obtain a gene expression profile;   (b) determining the prognosis of the patient based on the gene expression profile obtained in step (a).       

     Embodiment 2 
     Method according to embodiment 1, wherein the patient is a cancer or tumor patient. 
     Embodiment 3 
     Method according to embodiment 1 or 2, wherein the at least one marker gene is selected from the group consisting of marker genes set out in table 2. 
     Embodiment 4 
     Method according to embodiment 3, wherein the at least one marker gene is selected from the group consisting of marker genes set out in table 3. 
     Embodiment 5 
     Method according to embodiment 4, wherein the at least one marker gene is selected from group consisting of marker genes set out in table 4. 
     Embodiment 6 
     Method according to embodiment 5, wherein the at least one marker gene is selected from group consisting of marker genes set out in table 5. 
     Embodiment 7 
     Method according to embodiment 1, wherein at least 10 marker genes, preferably at least 30 marker genes, more preferably at least 50 marker genes, most preferably at least 100 marker genes are selected from table 1. 
     Embodiment 8 
     Method according to embodiment 3, wherein at least 10 marker genes, preferably at least 30 marker genes, more preferably at least 50 marker genes, most preferably at least 100 marker genes are selected from table 2. 
     Embodiment 9 
     Method according to embodiment 4, wherein at least 10 marker genes, preferably at least 30 marker genes, more preferably at least 50 marker genes are selected from table 3. 
     Embodiment 10 
     Method according embodiment 5, wherein at least 10 marker genes, preferably at least 20 marker genes, more preferably at least 30 marker genes a selected from the group consisting of from table 4. 
     Embodiment 11 
     Method according to any one of the preceding embodiments, wherein the expression level of at least one marker gene is measured before administration and/or after administration of at least one dose of a therapeutic agent. 
     Embodiment 12 
     Method according to embodiment 11, wherein the gene expression profile of step (a) is obtained by determining the difference of the expression level of the at least one marker gene measured before administration of the therapeutic agent and after administration of at least one dose of the therapeutic agent. 
     Embodiment 13 
     Method according to embodiment 11 or 12, wherein the therapeutic agent is an immunostimulatory composition and/or a vaccine and/or an immunotherapeutic agent. 
     Embodiment 14 
     Method according to any one of embodiments 11 to 13, wherein the immunostimulatory composition and/or vaccine comprises at least one antigen selected from the group consisting of MAGE-C1, MAGE-C2, NY-ESO-1, Survivin and 5T4 or fragments or variants thereof. 
     Embodiment 15 
     Method according to any one of embodiments 11 to 14, wherein the immunostimulatory composition and/or vaccine comprises the antigens MAGE-C1, MAGE-C2, NY-ESO-1, Survivin and 5T4 or fragments or variants thereof. 
     Embodiment 16 
     Method according to embodiment 11 to 15, wherein the antigen(s) are present as peptides or proteins and/or are encoded by at least one nucleotide sequence. 
     Embodiment 17 
     Method according to any one of embodiments 11 to 16, wherein the antigen(s) are encoded by at least one mRNA molecule. 
     Embodiment 18 
     Method according to any one of embodiments 11 to 17, wherein the cancer is selected from the group consisting of Acute Lymphoblastic Leukemia, Adult; Acute Lymphoblastic Leukemia, Childhood; Acute Myeloid Leukemia, Adult; Adrenocortical Carcinoma; Adrenocortical Carcinoma, Childhood; AIDS-Related Lymphoma; AIDS-Related Malignancies; Anal Cancer; Astrocytoma, Childhood Cerebellar; Astrocytoma, Childhood Cerebral; Bile Duct Cancer, Extrahepatic; Bladder Cancer; Bladder Cancer, Childhood; Bone Cancer, Osteosarcoma/Malignant Fibrous Histiocytoma; Brain Stem Glioma, Childhood; Brain Tumor, Adult; Brain Tumor, Brain Stem Glioma, Childhood; Brain Tumor, Cerebellar Astrocytoma, Childhood; Brain Tumor, Cerebral Astrocytoma/Malignant Glioma, Childhood; Brain Tumor, Ependymoma, Childhood; Brain Tumor, Medulloblastoma, Childhood; Brain Tumor, Supratentorial Primitive Neuroectodermal Tumors, Childhood; Brain Tumor, Visual Pathway and Hypothalamic Glioma, Childhood; Brain Tumor, Childhood (Other); Breast Cancer; Breast Cancer and Pregnancy; Breast Cancer, Childhood; Breast Cancer, Male; Bronchial Adenomas/Carcinoids, Childhood: Carcinoid Tumor, Childhood; Carcinoid Tumor, Gastrointestinal; Carcinoma, Adrenocortical; Carcinoma, Islet Cell; Carcinoma of Unknown Primary; Central Nervous System Lymphoma, Primary; Cerebellar Astrocytoma, Childhood; Cerebral Astrocytoma/Malignant Glioma, Childhood; Cervical Cancer; Childhood Cancers; Chronic Lymphocytic Leukemia; Chronic Myelogenous Leukemia; Chronic Myeloproliferative Disorders; Clear Cell Sarcoma of Tendon Sheaths; Colon Cancer; Colorectal Cancer, Childhood; Cutaneous T-Cell Lymphoma; Endometrial Cancer; Ependymoma, Childhood; Epithelial Cancer, Ovarian; Esophageal Cancer; Esophageal Cancer, Childhood; Ewing&#39;s Family of Tumors; Extracranial Germ Cell Tumor, Childhood; Extragonadal Germ Cell Tumor; Extrahepatic Bile Duct Cancer; Eye Cancer, Intraocular Melanoma; Eye Cancer, Retinoblastoma; Gallbladder Cancer; Gastric (Stomach) Cancer; Gastric (Stomach) Cancer, Childhood; Gastrointestinal Carcinoid Tumor; Germ Cell Tumor, Extracranial, Childhood; Germ Cell Tumor, Extragonadal; Germ Cell Tumor, Ovarian; Gestational Trophoblastic Tumor; Glioma. Childhood Brain Stem; Glioma. Childhood Visual Pathway and Hypothalamic; Hairy Cell Leukemia; Head and Neck Cancer; Hepatocellular (Liver) Cancer, Adult (Primary); Hepatocellular (Liver) Cancer, Childhood (Primary); Hodgkin&#39;s Lymphoma, Adult; Hodgkin&#39;s Lymphoma, Childhood; Hodgkin&#39;s Lymphoma During Pregnancy; Hypopharyngeal Cancer; Hypothalamic and Visual Pathway Glioma, Childhood; Intraocular Melanoma; Islet Cell Carcinoma (Endocrine Pancreas); Kaposi&#39;s Sarcoma; Kidney Cancer; Laryngeal Cancer; Laryngeal Cancer, Childhood; Leukemia, Acute Lymphoblastic, Adult; Leukemia, Acute Lymphoblastic, Childhood; Leukemia, Acute Myeloid, Adult; Leukemia, Acute Myeloid, Childhood; Leukemia, Chronic Lymphocytic; Leukemia, Chronic Myelogenous; Leukemia, Hairy Cell; Lip and Oral Cavity Cancer; Liver Cancer, Adult (Primary); Liver Cancer, Childhood (Primary); Lung Cancer, Non-Small Cell; Lung Cancer, Small Cell; Lymphoblastic Leukemia, Adult Acute; Lymphoblastic Leukemia, Childhood Acute; Lymphocytic Leukemia, Chronic; Lymphoma, AIDS-Related; Lymphoma, Central Nervous System (Primary); Lymphoma, Cutaneous T-Cell; Lymphoma, Hodgkin&#39;s, Adult; Lymphoma, Hodgkin&#39;s; Childhood; Lymphoma, Hodgkin&#39;s During Pregnancy; Lymphoma, Non-Hodgkin&#39;s, Adult; Lymphoma, Non-Hodgkin&#39;s, Childhood; Lymphoma, Non-Hodgkin&#39;s During Pregnancy; Lymphoma, Primary Central Nervous System; Macroglobulinemia, Waldenstrom&#39;s; Male Breast Cancer; Malignant Mesothelioma, Adult; Malignant Mesothelioma, Childhood; Malignant Thymoma; Medulloblastoma, Childhood; Melanoma; Melanoma, Intraocular; Merkel Cell Carcinoma; Mesothelioma, Malignant; Metastatic Squamous Neck Cancer with Occult Primary; Multiple Endocrine Neoplasia Syndrome, Childhood; Multiple Myeloma/Plasma Cell Neoplasm; Mycosis Fungoides; Myelodysplasia Syndromes; Myelogenous Leukemia, Chronic; Myeloid Leukemia, Childhood Acute; Myeloma, Multiple; Myeloproliferative Disorders, Chronic; Nasal Cavity and Paranasal Sinus Cancer; Nasopharyngeal Cancer; Nasopharyngeal Cancer, Childhood; Neuroblastoma; Neurofibroma; Non-Hodgkin&#39;s Lymphoma, Adult; Non-Hodgkin&#39;s Lymphoma, Childhood; Non-Hodgkin&#39;s Lymphoma During Pregnancy; Non-Small Cell Lung Cancer; Oral Cancer, Childhood; Oral Cavity and Lip Cancer; Oropharyngeal Cancer; Osteosarcoma/Malignant Fibrous Histiocytoma of Bone; Ovarian Cancer, Childhood; Ovarian Epithelial Cancer; Ovarian Germ Cell Tumor; Ovarian Low Malignant Potential Tumor; Pancreatic Cancer; Pancreatic Cancer, Childhood′, Pancreatic Cancer, Islet Cell; Paranasal Sinus and Nasal Cavity Cancer; Parathyroid Cancer; Penile Cancer; Pheochromocytoma; Pineal and Supratentorial Primitive Neuroectodermal Tumors, Childhood; Pituitary Tumor; Plasma Cell Neoplasm/Multiple Myeloma; Pleuropulmonary Blastoma; Pregnancy and Breast Cancer; Pregnancy and Hodgkin&#39;s Lymphoma; Pregnancy and Non-Hodgkin&#39;s Lymphoma; Primary Central Nervous System Lymphoma; Primary Liver Cancer, Adult; Primary Liver Cancer, Childhood; Prostate Cancer; Rectal Cancer; Renal Cell (Kidney) Cancer; Renal Cell Cancer, Childhood; Renal Pelvis and Ureter, Transitional Cell Cancer; Retinoblastoma; Rhabdomyosarcoma, Childhood; Salivary Gland Cancer; Salivary Gland′ Cancer, Childhood; Sarcoma, Ewing&#39;s Family of Tumors; Sarcoma, Kaposi&#39;s; Sarcoma (Osteosarcoma)/Malignant Fibrous Histiocytoma of Bone; Sarcoma, Rhabdomyosarcoma, Childhood; Sarcoma, Soft Tissue, Adult; Sarcoma, Soft Tissue, Childhood; Sezary Syndrome; Skin Cancer; Skin Cancer, Childhood; Skin Cancer (Melanoma); Skin Carcinoma, Merkel Cell; Small Cell Lung Cancer; Small Intestine Cancer; Soft Tissue Sarcoma, Adult; Soft Tissue Sarcoma, Childhood; Squamous Neck Cancer with Occult Primary, Metastatic; Stomach (Gastric) Cancer; Stomach (Gastric) Cancer, Childhood; Supratentorial Primitive Neuroectodermal Tumors, Childhood; T-Cell Lymphoma, Cutaneous; Testicular Cancer; Thymoma, Childhood; Thymoma, Malignant; Thyroid Cancer; Thyroid Cancer, Childhood; Transitional Cell Cancer of the Renal Pelvis and Ureter; Trophoblastic Tumor, Gestational; Unknown Primary Site, Cancer of, Childhood; Unusual Cancers of Childhood; Ureter and Renal Pelvis, Transitional Cell Cancer; Urethral Cancer; Uterine Sarcoma; Vaginal Cancer; Visual Pathway and Hypothalamic Glioma, Childhood; Vulvar Cancer; Waldenstrom&#39;s Macro globulinemia; and Wilms&#39; Tumor. 
     Embodiment 19 
     Method according to embodiment 18, wherein the cancer is lung cancer, preferably non-small cell lung cancer (NSCLC). 
     Embodiment 20 
     Method according to any one of the preceding embodiments, wherein the sample of the patient comprises peripheral blood mono-nuclear cells (PBMCs). 
     Embodiment 21 
     Method according to any one of the preceding embodiments, wherein in step (b) a hierarchical clustering algorithm is applied. 
     Embodiment 22 
     Kit, diagnostic composition or device for the analysis of at least one marker gene set out in table 1 comprising at least one primer and/or probe selective for determining the expression level of at least one marker gene set out in table 1. 
     Embodiment 23 
     Kit, diagnostic composition or device of embodiment 22, further comprising an enzyme for primer elongation, nucleotides and/or labeling agents. 
     Embodiment 24 
     Microarray, comprising at least one probe selective for determining the expression level of at least one marker gene set out in table 1. 
     Embodiment 25 
     Use of a microarray according to embodiment 24 for determining the prognosis of a cancer patient. 
     Embodiment 26 
     Use of a kit, diagnostic composition or device according to embodiment 22 or 23 for determining the prognosis of a cancer patient.