Patent Publication Number: US-2021171993-A1

Title: Polysaccharide-oxidizing composition and uses thereof

Description:
FIELD OF THE INVENTION 
     The present invention relates to field of production of sugar products by enzyme oxidation and hydrolysis of polysaccharide-containing material, and especially ligno-cellulosic biomass. 
     BACKGROUND OF THE INVENTION 
     Lignocellulosic biomass is a renewable source for the production of biofuels and platform molecules for the industry. Its conversion into valuable products requires the combined action of a variety of enzymes, most of which are obtained from fungal sources. In particular, the efficient conversion of cellulose to small molecules is carried out by the synergistic action of cellulases, i.e. endoglucanases (EG), cellobiohydrolases (CBH) and β-glucosidases. EG cleave β-1,4 linkages randomly within cellulose chains, thereby releasing new ends for the action of cellobiohydrolases (CBH) which in turn release cellobiose units. β-glucosidases produce glucose molecules from cellobiose, thereby alleviating the inhibiting effect of cellobiose on CBH. These enzymes are classified in various glycoside hydrolase (GH) families of the carbohydrate-active enzyme database (also termed CAZy; described notably at the internet address www.cazy.org, and by Lombard et al, 2014, Nucleic Acids Res, Vol. 42: 490-495). More recently, the contribution of lytic polysaccharide monooxygenase (LPMOs) to cellulose degradation has been demonstrated (Vaaje-Kolstad et al. 2010, Science, Vol. 330: 219-222; Harris et al. 2010, Biochemistry, Vol. 49: 3305-336; Quinlan et al. 2011, Proc Acad Natl Sci USA, Vol. 108: 15079-15084). In industry, addition of LPMOs to cellulolytic cocktails leads to the reduction of enzyme loading required for efficient saccharification of cellulosic biomass (Harris et al. 2010, Biochemistry, Vol. 49: 3305-3316; Johansen et al, 2016, Biochem Soc Trans, Vol. 44: 143-149). 
     In spite of much research effort, there remains a need for improved cellulose enzyme mixtures for the hydrolysis of cellulose in a pretreated lignocellulosic feedstock. The absence of such an enzyme mixture represents a large hurdle in the commercialization of cellulose conversion to soluble sugars including glucose for the production of ethanol and other products. 
     SUMMARY OF THE INVENTION 
     This invention provides for novel compositions comprising one or more specific polysaccharide-oxidizing enzymes. 
     The present invention relates to a polysaccharide-oxidizing composition comprising a polysaccharide-oxidizing enzyme wherein, when the said polysaccharide-oxidizing enzyme is compared to the reference polypeptide of SEQ ID NO. 1 by using the BLAST-P comparison method, (i) the said polysaccharide-oxidizing enzyme possesses an amino acid identity of 20% or more with the said reference polypeptide and (ii) the BLAST-P comparison method results in an E-value of 10 e −3  or less. 
     In some embodiments of the composition, the said polysaccharide-oxidizing enzyme has at least 30% amino acid identity with a polypeptide selected in a group comprising the polypeptides of SEQ ID NO. 1, SEQ ID NO. 2 and SEQ ID NO. 3 3. 
     In some embodiments of the composition, the said polysaccharide-oxidizing enzyme is encoded by a nucleic acid having at least 90% nucleotide identity with a nucleic acid selected in a group comprising the nucleic acids of SEQ ID NO. 4, SEQ ID NO. 5 and SEQ ID NO. 6. 
     In some embodiments, the said composition further comprises one or more lytic polysaccharide monooxygenases. 
     In some embodiments, the said composition further comprises one or more polysaccharide-degrading enzymes, selected in a group comprising cellulases, hemicellulases, ligninases, and carbohydrate oxidases. In some embodiments, the cellulases are selected in a group comprising exoglucanases, endoglucanases, cellobiohydrolases, cellulose phosphorylases, pectinases, pectate lyases, polygalacturonase, pectin esterases, cellobiose dehydrogenases, beta mannanases, arabino furnosidases, feruoyl esterases, arabino furanosidases, fructofuranosidases, alpha galactosidases, beta galactosidases, alpha amylases, acetylxylan esterases, chitin deacetylases, chitinases, and beta glucosidases. In some of these embodiments, the lytic polysaccharide monooxygenase is selected in a group comprising AA9, AA10, AA11 and AA13. 
     In some embodiments, the said one or more other polysaccharide degrading enzymes are comprised in an enzyme preparation containing the said one or more other polysaccharide degrading enzymes. In some embodiments, the said enzyme preparation comprises one or more enzymes originating from one or more fungus organisms or one or more bacterial organisms. 
     In some embodiments of the polysaccharide-oxidizing composition, one or more of the said other polysaccharide degrading enzymes are recombinant proteins. 
     This invention also pertains to a yeast cell recombinantly expressing a polysaccharide-oxidizing enzyme as defined in the present specification. 
     This invention also concerns a method for oxidizing a polysaccharide comprising a step of contacting one or more polysaccharides with a polysaccharide-oxidizing enzyme as defined in the present specification, or with a composition comprising the said polysaccharide-oxidizing enzyme. In some embodiments, the said one or more polysaccharides are contained in a lignocellulosic-containing material. 
     The present invention further relates to a method for the preparation of a sugar product from a polysaccharide-containing material comprising a step of treating the said polysaccharide-containing material in the presence of a polysaccharide degrading composition as described in the present specification. In some embodiments, the said method which comprises the steps of:
         a) providing a polysaccharide-containing material,   b) subjecting the said polysaccharide-containing material to hydrolysis in the presence of a polysaccharide-degrading composition as defined herein, and   c) collecting the sugar product obtained at the end of step b).       

     This invention also provides for a method for the preparation of a fermentation product from a polysaccharide-containing material comprising the steps of:
         a) providing a polysaccharide-containing material,   b) subjecting the said polysaccharide-containing material to hydrolysis in the presence of a polysaccharide-degrading composition as defined herein, whereby a sugar product is obtained, and   c) fomenting the sugar product collected at step c), whereby a fermentation product is obtained.       

    
    
     
       DESCRIPTION OF THE FIGURES 
         FIG. 1  illustrates a photograph of the gel electrophoresis on SDS-PAGE of the recombinant proteins of SEQ ID NO. 1, SEQ ID NO. 2 and SEQ ID NO. 3 produced in  Pichia pastoris . Lane 1: 10 μg of the purified protein of SEQ ID NO. 3. Lane 2:10 μg of protein of SEQ ID NO. 1. Lane 3: 10 μg of protein of SEQ ID NO. 2. Lane 4: molecular weight protein markers. 
         FIG. 2  illustrates the effect of enzyme concentration on H 2 O 2  production. (i) Upper curve with symbol □: protein of SEQ ID NO. 1, (ii) Lower curve with symbol Δ: protein of SEQ ID NO. 2. (iii) Medium curve with symbol x: protein of SEQ ID NO. 3. (iv) symbol ⋄: Control containing the reaction mixture without proteins of SEQ ID NO. 1, SEQ ID NO. 2 or SEQ ID NO. 3, and shows the background level of H 2 O 2  production (without enzyme). Abscissa:Concentration of protein, as expressed in micromolar. Ordinate:slope of hydrogen peroxide production, as expressed in Arbitrary Units. 
         FIG. 3  illustrates the results of a saccharification process in the presence of SEQ ID NO. 1 or SEQ ID NO. 2. Supplementation of  T. reesei  enzymatic cocktail with SEQ ID NO. 1 ( FIG. 3A ) or SEQ ID NO. 2 ( FIG. 31 ) for the saccharification of pretreated poplar (filled bars), birchwood fibres (dashed bars), cellulose (dotted bars). Quantification of glucose release was monitored by ionic chromatography, the measured values being expressed as Arbitrary Units of glucose peak area. The synergistic effect of SEQ ID NO. 1 or SEQ ID NO. 2 with  T. reesei  cellulases is compared with the control ( T. reesei  cellulases only) 
         FIG. 4  illustrates the results of a saccharification process in the presence of  T. reesei  cellulase cocktail supplemented with increasing amounts of either SEQ ID NO. 1 or SEQ ID NO. 2 by measuring the release of glucose by ionic chromatography.  FIG. 4A : Graph of the measured glucose peak area for increasing amounts of SEQ ID NO. 1.  FIG. 4B : Graph of the measured glucose peak area for increasing amounts of the protein of SEQ ID NO. 2. Ordinate: chromatography signal as expressed in Arbitrary Units. Abscissa of  FIG. 4A : bars from the left side to the right side of the figure: 1. absence of protein of SEQ ID NO. 1 or SEQ ID NO. 2; 2. Final concentration in the assay of 0.22 μM of protein mixture of SEQ ID NO. 1 and SEQ ID NO. 2; 3. Final concentration in the assay of 1.1 μM of a protein mixture of SEQ ID NO. 1 and SEQ ID NO. 2; 4. Final concentration in the assay of 2.2 μM of a protein mixture of SEQ ID NO. 1 and SEQ ID NO. 2 
       Abscissa of  FIG. 4B : bars from the left side to the right side of the figure: 1. absence of protein of SEQ ID NO. 1 or SEQ ID NO. 2, 2. Final concentration in the assay of 0.22 μM of protein mixture of SEQ ID NO. 2; 3. Final concentration in the assay of 1.1 μM of a protein mixture of SEQ ID NO. 2; 4. Final concentration in the assay of 2.2 μM of a protein mixture of SEQ ID NO. 2 
         FIG. 5  illustrates the results of a saccharification process in the presence of  T.reesei  enzymatic cocktail supplemented by a AA9 lytic polysaccharide monooxygenase and protein of SEQ ID NO. 1, by measuring the release of glucose by ionic chromatography. Abscissa: bars from the left side to the right side of the figure: 1. absence of protein of SEQ ID NO. 1 or AA9, 2. 2.2 μM of protein of SEQ ID NO. 1, 3.2.2 μM of AA9, 4. 1.1 μM of a protein of SEQ ID NO. 1 and 1.1 μM of AA9. 
         FIG. 6 : Phylogenetic tree of the AAxx family showing that the AAxx family members strongly cluster together and are very distant from AA9, AA10, AA11 and AA13 sequences respectively. 
         FIG. 7 : Line diagram of PcAAxx LPMO active site. 
         FIG. 8A-8B : Consensus sequence logo based on alignment of 283 sequences belonging to the catalytic module of AAxx family revealing the first Histidine as a conserved residue amongst the family. 
         FIG. 9 : Contribution of PcAAxx enzymes to the saccharification of woody biomass. Glucose release upon saccharification of pretreated pine and poplar by the CL847  Trichoderma reesei  enzyme cocktail (18) in the presence of 1 μM of PcAAxxA or PcAAxxB and 1 mM ascorbic acid. Glucose was quantified using ionic chromatography. Error bars indicate standard deviations from triplicate independent experiments. 
         FIG. 10 : Contribution of PcAAxx enzymes to the saccharification of woody biomass in the presence and in the absence of Ascorbate. Saccharification assays in the presence and absence of ascorbate on pine (A), and poplar (B). PcAAxxA (of SEQ ID No 1) and PcAAxxB (of SEQ ID No 2) were added to a concentration of 1 μM. Error bars indicate standard deviations from triplicate independent experiments. 
     
    
    
     DETAILED DESCRIPTION OF THE INVENTION 
     Any citation mentioned herein is incorporated by reference. 
     Throughout the present specification and the accompanying claims, the words “comprise” and “include” and variations such as “comprises”, “comprising”, “includes” and “including” are to be interpreted inclusively. That is, these words are intended to convey the possible inclusion of other elements or integers not specifically recited, where the context allows. The articles “a” and “an” are used herein to refer to one or to more than one (i.e. to one or at least one) of the grammatical object of the article. By way of example, “an element” may mean one element or more than one element. 
     The inventors have identified a family of proteins endowed with a polysaccharide-degrading activity that may be used in processes requiring the production of sugar products from starting polysaccharide materials, in particular polysaccharide biomass, and especially in processes requiring the production of sugar products from starting lignocellulosic materials, such as highly refractory xylan-coated cellulose fibers. 
     Further, the inventors have shown herein that the said protein family members have the ability to substantially increase the rate or the level of polysaccharide hydrolysis, in an amount-dependent manner. The members of the said family of proteins that has been identified herein has the property of producing hydrogen peroxide in the presence of oxygen and of an electron donor such as ascorbic acid. This is why these proteins which are described in the present application may also be encompassed by the term “polysaccharide-oxidizing enzyme” herein. 
     This novel family of polysaccharide-oxidizing enzymes is also referred herein as the “AAxx” family of proteins. The inventors have further characterized structurally the reference protein PcAAxxB (Genbank #KY769370) from  P.coccineus , by solving the crystallographic structure of its catalytic module at a resolution of 3 Å, thus providing a structural template for identifying all the relevant members of this AAxx family of enzymes, in complement to a sequence alignment of more than 300 proteins with significant similarity to PcAAxxB. 
     In particular, the polysaccharide-oxidizing enzymes of the invention are characterized by the presence of a conserved copper-binding active site, also referred herein as a copper-binding “histidine brace active site”, formed by two Histidine residues and a Tyrosine, one of those two Histidine residues being the N-terminal histidine after cleavage of the signal peptide. 
     Even more particularly, the inventors have shown herein that a plurality of proteins belonging to this novel AAxx family can be distinguished from other lytic polysaccharide monooxygenases in that they do not harbor a carbohydrate-binding module (CBM). 
     Illustratively, the examples herein show that the said protein family members substantially increase the level of polysaccharide degradation caused by a polysaccharide-degrading enzyme mixture. Notably, the examples herein show that protein members of the family of polysaccharide-oxidizing enzymes identified by the inventors substantially increase the level of glucose release caused by the action of an enzyme mixture originating from  T. reesei  on a cellulose-containing material, which encompasses a lignocellulosic material. 
     Still further, the inventors have shown that a polysaccharide-oxidizing protein that has been newly identified herein may act in synergy with known other polysaccharide-oxidizing enzymes such as lytic polysaccharide monooxygenases (which are also commonly termed LPMOs) for enhancing the polysaccharide hydrolysis caused by a polysaccharide-degrading enzyme mixture, and especially for enhancing the hydrolysis of a lignocellulosic material caused by an enzyme mixture comprising cellulases. 
     These further experimental evidences described herein show that the polysaccharide-oxidizing enzymes identified by the inventors may target distinct sugar units constitutive of a polysaccharide (e.g. cellulose, hemicellulose or lignocellulose), or alternatively distinct chemical groups of same sugar units, as compared to the sugar units, or the chemical groups, which are targeted by the known LPMOs, such as AA9 (also termed GH61), AA10, AA11 and AA13. 
     Thus, it has been unexpectedly found by the inventors that the polysaccharide-oxidizing enzymes identified herein may synergize with cellulases for degrading polysaccharide-containing material, such as cellulose-containing material like lignocellulose. 
     It has also been unexpectedly found herein that the polysaccharide-oxidizing enzymes identified herein may synergize with LPMOs for degrading polysaccharide-containing material, such as cellulose-containing material like lignocellulose. 
     Without wishing to be bound by the theory, there inventors are of the opinion that AAxx enzymes of the invention may act preferably on the xylans that are bound to cellulose, especially xylans that have a rigidity and a conformation similar to that of the underlying cellulose chains. 
     Accordingly, the polysaccharide-oxidizing enzymes of the invention can be considered either alone, or in combination with other polysaccharide-oxidizing and/or polysaccharide-degrading enzymes, and mixtures thereof. 
     Thus, the inventors have identified a novel class of polysaccharide-oxidizing enzymes that may be used in a large variety of processes for degrading polysaccharide-containing material, and especially in a large variety of processes for degrading lignocellulosic material. 
     The present invention provides for a novel class of polysaccharide-oxidizing enzymes which, when a polysaccharide-oxidizing enzyme thereof is compared to the reference polypeptide of SEQ ID NO. 1 by using the BLAST-P comparison method, (i) the said polysaccharide-oxidizing enzyme possesses an amino acid identity of 20% or more with the said reference polypeptide and (ii) the BLAST-P comparison result for the said polysaccharide-oxidizing enzyme comprises an E-value of 10 e −3  or less. 
     In particular, the inventors have identified a crystallographic structure of a polypeptide of sequence SEQ ID NO. 2. Thus the present invention also relates to polysaccharide-oxidizing enzymes which, when a polysaccharide-oxidizing enzyme thereof is compared to the reference polypeptide of SEQ ID NO. 2 by using the BLAST-P comparison method, (i) the said polysaccharide-oxidizing enzyme possesses an amino acid identity of 20% or more with the said reference polypeptide and (ii) the BLAST-P comparison result for the said polysaccharide-oxidizing enzyme comprises an E-value of 10 e −3  or less. 
     BLAST-P method (also termed Protein Basic Local Alignment Search Tool method) is well known from the one skilled in the art. BLAST-P method is notably described by Altschul et al. (1990. J Mol Biol, Vol. 215 (no 3):403-410), Altschul et al. (1997, Nucleic Acids Res. Vol. 25:3389-3402) and Altschul et al. (2005, FEBS J. Vol. 272:5101-5109). BLAST-P method may be performed by using the NCBI tool that is available on-line (internet address: http://blast.ncbi.nlm.nih.gov/Blast.cgi?PAGE=Proteins). 
     When used herein, the BLAST-P method shall preferably be used with the following parameters: (i) Expected threshold: 10; (ii) Word Size: 6: (iii) Max Matches in a Query range: 0; (iv) Matrix: BLOSSUM62; (v) Gap costs: Existence 11, Extension 1; (vi) Compositional Adjustments: Conditional compositional score matrix adjustment, (vii) No filter (viii) No mask. 
     As it is well known, the score of an alignment, S, is calculated as the sum of substitution and gap scores. Substitution scores are given by a look-up table (see PAM, BLOSUM hereunder). Gap scores are typically calculated as the sum of G, the gap opening penalty and L, the gap extension penalty. For a gap of length n, the gap cost would be G+Ln. The choice of gap costs, G and L is empirical, but it is customary to choose a high value for G (10-15) and a low value for L (1-2). 
     An optimal alignment means an alignment of two sequences with the highest possible score. 
     The amino acid identity means the extent to which two amino acid sequences have the same residues at the same positions in an alignment, often expressed as a percentage. 
     A Blocks Substitution Matrix (BLOSSUM) is a substitution scoring matrix in which scores for each position are derived from observations of the frequencies of substitutions in blocks of local alignments in related proteins. Each matrix is tailored to a particular evolutionary distance. In the BLOSUM62 matrix, for example, the alignment from which scores were derived was created using sequences sharing no more than 62% identity. Sequences more identical than 62% are represented by a single sequence in the alignment so as to avoid over-weighting closely related family members. 
     As used herein, an “E-value” (also termed Expect Value”) is a parameter calculated when using the BLAST-P method, the said parameter representing the number of different alignments with scores equivalent to or better than S that is expected to occur in a database search by chance. The lower the E value, the more significant the score and the alignment. 
     The inventors have identified more than 300 polypeptides that display significant comparison scores over their entire sequence length, when these polypeptides are compared to the polypeptide of SEQ ID NO. 1 by using the BLAST-P method. 
     Accordingly, the inventors have identified more than 300 polypeptides wherein, when any one of these polypeptides is compared to the reference polypeptide of SEQ ID NO. 1 by using the BLAST-P comparison method, (i) the said member possesses an amino acid identity of 20% or more with the said reference polypeptide and (ii) the BLAST-P comparison method results in an E-value of 10 e −3  or less. 
     Illustratively, there is described herein the polysaccharide-oxidizing enzyme of SEQ ID NO. 2, which possesses an amino acid identity of 66% with the reference polypeptide of SEQ ID NO. 1 and has an E-value of 4 e −133 , when using the BLAST-P comparison method. 
     As shown in the examples herein, the polysaccharide-oxidizing enzyme of SEQ ID NO. 2, like the polysaccharide-oxidizing enzyme of SEQ ID NO. 1, has the ability to produce H 2 O 2  in the presence of oxygen and an electron donor compound. Further, the polysaccharide-oxidizing enzyme of SEQ ID NO. 2, possesses polysaccharide degrading activity, as shown herein in a sequential lignocellulose degradation assay. 
     Still illustratively, there is described herein the polysaccharide-oxidizing enzyme of SEQ ID NO. 3, which possesses an amino acid identity of 34% with the reference polypeptide of SEQ ID NO. 1 and has an E-value of 2 e −40 , when using the BLAST-P comparison method. 
     As shown in the examples herein, the polysaccharide-oxidizing enzyme of SEQ ID NO. 2, like the polysaccharide-oxidizing enzyme of SEQ ID NO. 1, has the ability to produce H 2 O 2  in the presence of oxygen and an electron donor compound, like the polysaccharide-oxidizing enzyme of SEQ ID NO. 2 and SEQ ID NO. 3. 
     Analyses of the sequence alignment by the inventors revealed that a conserved histidine residue is always present at the N-terminal position of each of these polypeptide sequences. 
     In particular, the polysaccharide-oxidizing enzymes of the invention are characterized by the presence of a conserved copper-binding active site, also referred herein as a copper-binding “histidine brace active site”, formed by two Histidine residues and a Tyrosine, one of those two Histidine residues being the N-terminal histidine. 
     According to another (non-mutually exclusive) embodiment, the polysaccharide-oxidizing enzymes of the invention may be N- and or O-glycosylated. 
     For reference, a polysaccharide-oxidizing enzyme of SEQ ID NO. 2 may be N-glycosylated on at least one Asparagine (Asn) residue, selected from Asn 13, Asn76, Asn133, Asn183 and Asn217. 
     As used herein, a N-glycosylation on at least one Asparagine residue, may include one residue, two, three, four or five of said Asn residues; or if applicable all of Asn residues. 
     As used herein, a “polysaccharide-oxidizing enzyme” encompasses a polypeptide having the following properties:
         the said polypeptide produces hydrogen peroxide in the presence of oxygen and an electron donor compound, such as ascorbate,   the said polypeptide increases in a dose-dependent manner, in the presence or in the absence of an electron donor, the degradation of a polysaccharide-containing material, such as lignocellulose, caused by cellulases and/or xylanases.   the said polypeptide increases in a dose-dependent manner, in the presence or in the absence of an electron donor, the degradation of a polysaccharide-containing material, such as lignocellulose, caused by cellulases, in the presence of one or more LPMOs, such as LPMOs selected in a group comprising AA9, AA10, AA11 and AA13.       

     In particular, a “polysaccharide-oxidizing enzyme” of the invention has been shown to be particularly efficient in oxidizing xylans, especially xylans that are absorbed onto cellulose. 
     The term “electron donor” is used herein in its usual meaning for the one skilled in the art. Thus, an electron donor compound is a chemical entity that donates electrons to another compound. An electron donor compound is a reducing agent by virtue of its donating electrons and is itself oxidized when donating electrons to another chemical entity. An electron donor, as specified above for the polysaccharide-oxidizing properties, encompasses, in a non-exhaustive manner, ascorbate and cellobiose dehydrogenase (CDH). 
     In the absence of a reductant, such as ascorbate, the reducing agent may advantageously be provided by the biomass (e.g. lignin), which could act as an electron donor. 
     The present invention also provides for uses of the said class of polysaccharide-oxidizing enzymes in various polysaccharide degradation processes, including in processes for degrading lignocellulosic material. 
     The present invention also provides for compositions comprising one or more of the said polysaccharide-oxidizing enzymes, and optionally polysaccharide degrading enzymes such as cellulases or lytic polysaccharide monooxygenases (LPMOs). 
     The present invention provides for a polysaccharide-oxidizing composition comprising a polysaccharide-oxidizing enzyme wherein, when the said polysaccharide-oxidizing enzyme is compared to the reference polypeptide of SEQ ID NO. 1 by using the BLAST-P comparison method, (i) the said polysaccharide-oxidizing enzyme possesses an amino acid identity of 20% or more with the said reference polypeptide and (ii) the BLAST-P comparison method results in an E-value of 10 c or less. 
     In some embodiments, a polysaccharide-oxidizing enzyme wherein, when the said polysaccharide-oxidizing enzyme is compared to the reference polypeptide of SEQ ID NO. 1 by using the BLAST-P comparison method, (i) the said polysaccharide-oxidizing enzyme possesses an amino acid identity of 20% or more with the said reference polypeptide and (ii) the BLAST-P comparison method results in an E-value of 10 e −3  or less consists of the polypeptide of SEQ ID NO. 2. As already specified elsewhere herein, the polypeptide of SEQ ID NO. 2 has 66% amino acid identity with SEQ ID NO. 1 and an E value of 4 e −133 . 
     As specified herein a polypeptide comprising SEQ ID No 2 may comprise, or consist of, a polypeptide of SEQ ID No 7. 
     In some other embodiments, a polysaccharide-oxidizing enzyme wherein, when the said polysaccharide-oxidizing enzyme is compared to the reference polypeptide of SEQ ID NO. 1 by using the BLAST-P comparison method, (i) the said polysaccharide-oxidizing enzyme possesses an amino acid identity of 20% or more with the said reference polypeptide and (ii) the BLAST-P comparison method results in an E-value of 10 e −3  or less consists of the polypeptide of SEQ ID NO. 3. As already specified elsewhere herein, the polypeptide of SEQ ID NO. 3 has 34% amino acid identity with SEQ ID NO. 1 and an E value of 2 e −40 . 
     Further, the polypeptide of SEQ ID NO. 3 has 37% amino acid identity with SEQ ID NO. 2 and an E value of 5 e −44 . 
     This invention also pertains to such compositions, wherein the said polysaccharide-oxidizing enzyme is encoded by a nucleic acid having at least 20% nucleotide identity with a nucleic acid selected in a group comprising the nucleic acids of SEQ ID NO. 4, SEQ ID NO. 5 and SEQ ID NO. 6. 
     This invention also pertains to such compositions, wherein the said polysaccharide-oxidizing enzyme is encoded by a nucleic acid having at least 20% nucleotide identity with a nucleic acid selected in a group comprising nucleic acids encoding a polypeptide of SEQ ID NO. 7. 
     Within the scope of the present invention, the “percentage identity” between two polypeptides means the percentage of identical amino acids residues between the two polypeptide sequences to be compared, obtained after optimal alignment, this percentage being purely statistical and the differences between the two polypeptide sequences being distributed randomly along their length. The comparison of two polypeptide sequences is traditionally carried out by comparing the sequences after having optimally aligned them, said comparison being able to be conducted by segment or by using an “alignment window”. Optimal alignment of the sequences for comparison is carried out, by using the comparison software BLAST-P). 
     In its principle, the percentage identity between two amino acid sequences is determined by comparing the two optimally-aligned sequences in which the nucleic acid sequence to compare can have additions or deletions compared to the reference sequence for optimal alignment between the two polypeptide sequences. Percentage identity is calculated by determining the number of positions at which the amino acid residue is identical between the two sequences, preferably between the two complete sequences, dividing the number of identical positions by the total number of positions in the alignment window and multiplying the result by 100 to obtain the percentage identity between the two sequences. 
     As intended herein, polypeptide sequences having at least 20% amino acid identity with a reference sequence encompass those having at least 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29%, 30%, 31%, 32%, 33%, 34%, 35%, 36%, 37%, 38%, 39%, 40%, 41%, 42%, 43%, 44%, 45%, 46%, 47%, 48%, 49%, 50%, 51%, 52%, 53%, 54%, 55%, 56%, 57%, 28%, 59%, 60%, 61%, 62%, 63%, 64%, 65%, 66%, 67%, 68%, 69%, 70%, 71%, 72%, 73%, 74%, 75%, 76%, 77%, 78%, 79%, 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98% and 99% amino acid identity with the said reference sequence. 
     In some embodiments of a composition described herein, the said polysaccharide-oxidizing enzyme has at least 30% amino acid identity with a polypeptide selected in a group comprising the polypeptides of SEQ ID NO. 1. SEQ ID NO. 2 and SEQ ID NO. 3. Particularly, the polysaccharide-oxidizing enzymes encompass those having at least 30% amino acid identity with the polypeptide of SEQ ID NO. 1 
     In some embodiments of a composition described herein, the said polysaccharide-oxidizing enzyme has at least 60% amino acid identity with a polypeptide selected in a group comprising the polypeptides of SEQ ID NO. 1, SEQ ID NO. 2 and SEQ ID NO. 3. Particularly, the polysaccharide-oxidizing enzymes encompass those having at least 60% amino acid identity with the polypeptide of SEQ ID NO. 1 
     In some embodiments of a composition described herein, the said polysaccharide-oxidizing enzyme has at least 90% amino acid identity with a polypeptide selected in a group comprising the polypeptides of SEQ ID NO. 1, SEQ ID NO. 2 and SEQ ID NO. 3. Particularly, the polysaccharide-oxidizing enzymes encompass those having at least 90% amino acid identity with the polypeptide of SEQ ID NO. 1. 
     In some embodiments of a composition described herein, the said polysaccharide-oxidizing enzyme has at least 30% amino acid identity with a polypeptide of SEQ ID NO. 3. 
     In some embodiments of a composition described herein, the said polysaccharide-oxidizing enzyme has at least 60% amino acid identity with a polypeptide of SEQ ID NO. 3. 
     In some embodiments of a composition described herein, the said polysaccharide-oxidizing enzyme has at least 90% amino acid identity with a polypeptide of SEQ ID NO. 3. 
     In some embodiments of a composition described herein, the said polysaccharide-oxidizing enzyme is encoded by a nucleic acid having at least 90% nucleotide identity with a nucleic acid selected in a group comprising the nucleic acids of SEQ ID NO. 4, SEQ ID NO. 5 and SEQ ID NO. 6. 
     In some embodiments of a composition described herein, the said polysaccharide-oxidizing enzyme has at least 20% (or even 30%) amino acid identity with a polypeptide of sequence SEQ ID No 7. Particularly, the polysaccharide-oxidizing enzymes encompass those having at least 60% or even 90% amino acid identity with a polypeptide of SEQ ID NO. 7. 
     Similarly, the “percentage identity” between two sequences of nucleic acids means the percentage of identical nucleotide residues between the two nucleic acid sequences to be compared, obtained after optimal alignment, this percentage being purely statistical and the differences between the two sequences being distributed randomly along their length. The comparison of two nucleic acid sequences is traditionally carried out by comparing the sequences after having optimally aligned them, said comparison being able to be conducted by segment or by using an “alignment window”. Optimal alignment of the sequences for comparison is carried out, by using the comparison software BLAST-N). 
     In its principle, the percentage identity between two nucleic acid sequences is determined by comparing the two optimally-aligned sequences in which the nucleic acid sequence to compare can have additions or deletions compared to the reference sequence for optimal alignment between the two sequences. Percentage identity is calculated by determining the number of positions at which the nucleotide residue is identical between the two sequences, preferably between the two complete sequences, dividing the number of identical positions by the total number of positions in the alignment window and multiplying the result by 100 to obtain the percentage identity between the two sequences. 
     As intended herein, nucleotide sequences having at least 20% nucleotide identity with a reference sequence encompass those having at least 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29%, 30%, 31%, 32%, 33%, 34%, 35%, 36%, 37%, 38%, 39%, 40%, 41%, 42%, 43%, 44%, 45%, 46%, 47%, 48%, 49%, 50%, 51%, 52%, 53%, 54%, 55%, 56%, 57%, 28%, 59%, 60%, 61%, 62%, 63%, 64%, 65%, 66%, 67%, 68%, 69%, 70%, 71%, 72%, 73%, 74%, 75%, 76%, 77%, 78%, 79%, 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98% and 99% nucleotide identity with the said reference sequence. 
     As used herein, an E-value of 10 e or less encompasses E-values of 1 e −3  or less, 1 e −4  or less, 1 e −5  or less, 1 e −6  or less, 1 e −7  or less, 1 e −8  or less, 1 e −9  or less, 1 e −10  or less, 1 e −20  or less, 1 e −30  or less, 1 e −40  or less, 1 e −50  or less, 1 e −60  or less, 1 e −70  or less, 1 e −80  or less, 1 e −90  or less and 1 e −100  or less. 
     Illustratively, as already specified elsewhere herein, when the polysaccharide-oxidizing enzyme of SEQ ID NO. 2 is compared to the reference polypeptide of SEQ ID NO. 1 by using the comparison method BLAST-P, (i) the said polysaccharide-oxidizing enzyme of SEQ ID NO. 2 possesses an amino acid identity of 66% with the reference polypeptide of SEQ ID NO. 1 and (ii) the BLAST-P comparison method results in an E-value of 4 e −133 . 
     Still illustratively, as already specified elsewhere herein, when the polysaccharide-oxidizing enzyme of SEQ ID NO. 3 is compared to the reference polypeptide of SEQ ID NO. 1 by using the comparison method BLAST-P, (i) the said polysaccharide-oxidizing enzyme of SEQ ID NO. 3 possesses an amino acid identity of 34% with the reference polypeptide of SEQ ID NO. 1 and (ii) the BLAST-P comparison method results in an E-value of 2 e −10 . 
     In preferred embodiments, the said polysaccharide-oxidizing enzyme is selected in a group comprising the polypeptides having the following GenBank reference numbers: ALO60293.1; CCA68158.1; CCA68159.1; CCA68161.1; CCA71530.1; CCA72554.1; CCA72555.1; CCO30796.1; CCT73728.1; CDM26384.1; CDO76981.1; CDO76983.1; CDO76990.1; CDR41535.1; CDZ98469.1; CDZ98532.1; CDZ98792.1; CDZ98793.1; CEJ62913.1; CEJ80690.1; CEL55274.1; CEL55761.1; CEN61973.1; CEQ41736.1; CRL20539.1; CUA74138.1; CUA75968.1; EEB87294.1; EEB88604.1; EEB93106.1; EGU12035.1; EGU79270.1; EJU02917.1; EJU04796.1; EJU04797.1; EKC98083.1; EKD01731.1; EKD04876.1; EKG10038.1; ELU37011.1; ELU44209.1; EMD31282.1; EMD34047.1; EMT65805.1; ENH74989.1; EPT05587.1; EPT05590.1; EPT05591.1; EUC56978.1; EUC64931.1; EWG51104.1; EWY85510.1; EXK29887.1; EXU99300.1; GAO89447.1; GAQ10202.1; GAT49547.1; GAT49548.1; GAT52486.1; GAT61130.1; GAT61131.1; KDE05902.1; KDE09071.1; KDN48575.1; KDN50638.1; KDQ07356.1; KDQ08649.1; KDQ08700.1; KDQ08703.1; KDQ11515.1; KDQ12702.1; KDQ15932.1; KDQ19064.1; KDQ25667.1; KDQ34148.1; KDQ59091.1; KDQ59092.1; KDR69809.1; KDR78641.1; KDR82083.1; KEP48245.1; KEY82804.1; KFG85718.1; KFH41721.1; KFY94807.1; KFZ00858.1; KFZ20368.1; KGB74552.1; KID86720.1; KII89650.1; KII89670.1; KIJ14235.1; KIJ14422.1; KIJ36788.1; KIJ36789.1; KIJ36910.1; KIJ36911.1; KIJ59037.1; KIJ62866.1; KIJ66712.1; KIJ93961.1; KIK01335.1; KIK01364.1; KIK03019.1; KIK24220.1; KIK24223.1; KIK45012.1; KIK47453.1; KIK58046.1; KIK60325.1; KIK64405.1; KIK64418.1; KIK64426.1; KIK64427.1; KIK64461.1; KIK94802.1; KIL59842.1; KIL67972.1; KIL68458.1; KIL88744.1; KIM29500.1; KIM34148.1; KIM35038.1; KIM39331.1; KIM49751.1; KIM57407.1; KIM60439.1; KIM60441.1; KIM60443.1; KIM60444.1; KIM84967.1; KIM93034.1; KIM95301.1; KIM95307.1; KIN08100.1; KIN97734.1; KIN97736.1; KIN97737.1; KIO31600.1; KIP08019.1; KIP08026.1; KIP10435.1; KIR25380.1; KIR50229.1; KIR55806.1; KIR67208.1; KIW62805.1; KIY36322.1; KIY46248.1; KIY46262.1; KIY46497.1; KIY46927.1; KIY47293.1; KIY51548.1; KIY64670.1; KIY68736.1; KIY71843.1; KJA14486.1; KJA19114.1; KJA20550.1; KJA20613.1; KJK82496.1; KKO98459.1; KKP01653.1; KLT38889.1; KLT39034.1; KLT43002.1; KLT43602.1; KLT43893.1; KLT46239.1; KMK54965.1; KNZ77897.1; KNZ78922.1; KPA38710.1; KPI34779.1; KPM37038.1; KPV71930.1; KPV77521.1; KPV77742.1; KTB29212.1; KTB33212.1; KUE98996.1; KUE99426.1; KWU44348.1; KWU44477.1; KXH42132.1; KXH43636.1; KXH51881.1; KXN82218.1; KXN84873.1; KXN89494.1; KXN90938.1; KXN93349.1; KYQ38716.1; KYQ40395.1; KYQ41811.1; KZL64940.1; KZO90689.1; KZO90691.1; KZP14545.1; KZP23879.1; KZS91941.1; KZT07581.1; KZT07590.1; KZT20429.1; KZT29895.1; KZT40257.1; KZT57664.1; KZT57666.1; KZT73200.1; KZT73202.1; KZV68182.1; KZV68185.1; KZV69208.1; KZV72373.1; KZV79310.1; KZV79844.1; KZV82398.1; KZV83782.1; KZV85461.1; KZV85472.1; KZV86197.1; KZV88440.1; KZV88442.1; KZV88448.1; KZV96582.1; KZV97371.1; KZV97738.1; KZV97742.1; KZV98356.1; KZV99282.1; KZW00468.1; KZW00469.1; OAA59408.1; OAA71978.1; OAG11613.1; OAG40496.1; OAL02191.1; OAL28870.1; OAL45637.1; OAP54840.1; OAQ60454.1; OAQ77899.1; OAQ86421.1; OAQ94383.1; OAQ97907.1; OAX34821.1; XP_001263997.1; XP_001796117.1; XP_001829371.2; XP_001835502.2; XP_001835509.1; XP_001836582.1; XP_001840021.2; XP_001877230.1; XP_001878077.1; XP_001885228.1; XP_001905249.1; XP_003035108.1; XP_003035505.1; XP_003036605.1; XP_003042172.1; XP_003191958.1; XP_006458724.1; XP_006459911.1; XP_006963793.1; XP_007001773.1; XP_007003269.1; XP_007262604.1; XP_007299807.1; XP_007301417.1; XP_007306950.1; XP_007318869.1; XP_007318871.1; XP_007319142.1; XP_007327029.1; XP_007329615.1; XP_007337360.1; XP_007343208.1; XP_007346002.1; XP_007349200.1; XP_007349275.1; XP_007351346.1; XP_007351348.1; XP_007351349.1; XP_007351518.1; XP_007352398.1; XP_007353707.1; XP_007359130.1; XP_007362490.1; XP_007362492.1; XP_007362499.1; XP_007362779.1; XP_007388801.1; XP_007388810.1; XP_007393138.1; XP_007393767.1; XP_007581903.1; XP_007600909.1; XP_007746185.1; XP_007765609.1; XP_007768205.1; XP_007792087.1; XP_007792157.1; XP_007826256.1; XP_007849383.1; XP_007867180.1; XP_007867564.1; XP_008039133.1; XP_008039347.1; XP_008039803.1; XP_008039807.1; XP_008718658.1; XP_008731148.1; XP_009256644.1; XP_009545121.1; XP_009545122.1; XP_011321625.1; XP_012046198.1; XP_01218150.1; XP_012183613.1; XP_013257070.1; XP_013271081.1; XP_013277879.1; XP_013332110.1; XP_013943298.1; XP_013944931.1; XP_013954691.1; XP_013960458.1; XP_014176455.1; XP_014180074.1; XP_014180075.1; XP_014181917.1; XP_014543483.1; XP_014573268.1; XP_016242373.1; XP_016271225.1; XP_016275235.1; XP_016275300.1; XP_016610141.1; XP_016620042.1; XP_016630521.1; XP_567250.1; XP_753127.1 and XP_778151.1. 
     In preferred embodiments, the said polysaccharide-oxidizing enzyme consists of a recombinant protein. In some of these preferred embodiments, the said recombinant protein is produced by a yeast cell that has been genetically transformed so as to express the said recombinant polysaccharide-oxidizing enzyme. 
     In some embodiments, the said polysaccharide-oxidizing composition comprises only one polysaccharide-oxidizing enzyme described herein, and especially only one polysaccharide-oxidizing enzyme having an amino acid sequence selected in a group comprising SEQ ID NO. 1, SEQ ID NO. 2, SEQ ID NO. 3, and the polysaccharide-oxidizing enzymes identified by their GenBank reference number herein. 
     In some embodiments, the said polysaccharide-oxidizing composition comprises only one polysaccharide-oxidizing enzyme encoded by a nucleic acid having a nucleic acid sequence selected in a group comprising SEQ ID NO. 4, SEQ ID NO. 5 and SEQ ID NO. 6. 
     In some other embodiments, the polysaccharide-oxidizing composition according to the invention comprises more than one polysaccharide-oxidizing enzyme described herein, and especially more than one polysaccharide-oxidizing enzyme having an amino acid sequence selected in a group comprising SEQ ID NO. 1, SEQ ID NO. 2, SEQ ID NO. 3 and the polysaccharide-oxidizing enzymes identified by their respective GenBank reference number herein. In some of these embodiments, the polysaccharide-oxidizing composition according to the invention comprises the polysaccharide-oxidizing enzymes of SEQ ID NO; 1, of SEQ ID NO. 2 and of SEQ ID NO. 3. 
     In some other embodiments, the polysaccharide-oxidizing composition according to the invention comprises more than one polysaccharide-oxidizing enzyme encoded by a nucleic acid having a nucleic acid sequence selected in a group comprising SEQ ID NO. 4, SEQ ID NO. 5, SEQ ID NO. 6 and the nucleic acid sequences encoding the polysaccharide-oxidizing enzymes identified by their respective GenBank reference number herein. In some of these other embodiments, the polysaccharide-oxidizing composition according to the invention comprises the polysaccharide-oxidizing enzymes encoded by nucleic acids having the nucleic acid sequences of SEQ ID NO. 4, of SEQ ID NO. 5 and of SEQ ID NO. 6. 
     According to some of these other embodiments, the polysaccharide-oxidizing composition comprises from 2 to 10 distinct polysaccharide-oxidizing enzymes having an amino acid sequence selected in a group comprising SEQ ID NO. 1, SEQ ID NO. 2, SEQ ID NO. 3 and the polysaccharide-oxidizing enzymes identified by their respective GenBank reference number herein. 
     According to some of these other embodiments, the polysaccharide-oxidizing composition comprises from 2 to 10 distinct polysaccharide-oxidizing enzymes having an amino acid sequence selected in a group comprising SEQ ID NO. 1, SEQ ID NO. 2 and SEQ ID NO. 3 and the polysaccharide-oxidizing enzymes identified by their respective GenBank reference number herein. 
     According to some of these other embodiments, the polysaccharide-oxidizing composition comprises from 2 to 10 distinct polysaccharide-oxidizing enzymes encoded by a nucleic acid having a nucleic acid sequence selected in a group comprising SEQ ID NO. 4, SEQ ID NO. 5, SEQ ID NO. 6 and the nucleic acids encoding the polysaccharide-oxidizing enzymes identified by their respective GenBank reference number herein. 
     According to these other embodiments, the polysaccharide-oxidizing composition comprises 2, 3, 4, 5, 6, 7, 8, 9 or 10 distinct polysaccharide-oxidizing enzymes as described herein. 
     In some further embodiments, a polysaccharide-oxidizing composition according to the invention further comprises one or more other polysaccharide-oxidizing enzymes, which other polysaccharide-oxidizing enzymes are preferably selected among lytic polysaccharide monooxygenases, which encompasses other polysaccharide-oxidizing enzymes selected in a group comprising AA9, AA10, AA11 and AA13 LPMOs. 
     In some embodiments, a polysaccharide-oxidizing composition described herein may be used as a ready-to-use composition for degrading a polysaccharide-containing material, which encompasses a ready-to-use composition for degrading a lignocellulosic material. 
     In other embodiments, a polysaccharide-oxidizing composition as described herein may consist of an auxiliary composition that may be used in combination with one or more distinct polysaccharide degrading enzymes in a process for degrading a polysaccharide-containing material. According to these other embodiments, the said one or more other polysaccharide degrading enzymes may be contained as an enzyme mixture in a polysaccharide-degrading composition. As it will be further described in the present specification, a variety of such polysaccharide-degrading enzyme mixtures are known in the art, which encompasses enzyme mixtures comprising cellulases, such as enzyme mixtures comprising fungus-derived cellulases. 
     As shown herein, a polysaccharide-oxidizing composition as described in the present specification, when used in combination with known polysaccharide-degrading enzymes, and especially when used in combination with a mixture of polysaccharide-degrading enzymes, allows a more easier and a more complete sugar product release from a polysaccharide-containing starting material. In particular, a polysaccharide-oxidizing composition as described in the present specification, when used in combination with known polysaccharide-degrading enzymes, and especially when used in combination with a mixture of polysaccharide-degrading enzymes, allows a more easier and a more complete glucose release from a cellulose-containing starting material, which includes a more easier and a more complete release of glucose from a lignocellulosic starting material. 
     As already specified herein, there is generally provided compositions comprising a polysaccharide-oxidizing enzyme selected in a group comprising SEQ ID NO. 1, SEQ ID NO. 2, SEQ ID NO. 3 and the polysaccharide-oxidizing enzymes identified by their respective GenBank reference number herein, as well as polysaccharide-oxidizing enzymes encoded by a nucleic acid having a nucleic acid sequence selected in a group comprising SEQ ID NO. 4, SEQ ID NO. 5, SEQ ID NO. 6 and the nucleic acids encoding the polysaccharide-oxidizing enzymes identified by their respective GenBank reference number herein. 
     According to one embodiment, the invention further provides a method for preparing a polysaccharide-oxidizing enzyme comprising the steps of: 
     a) providing a composition comprising an enzyme polypeptide wherein, when the said polypeptide is compared to a reference polypeptide selected in a group comprising SEQ ID NO. 1, SEQ ID NO. 2 and SEQ ID NO. 3, by using the BLAST-P comparison method, wherein (i) the said enzyme polypeptide possesses an amino acid identity of 20% or more with the said reference polypeptide and (ii) the BLAST-P comparison method results in an E-value of 10 e −3  or less; 
     b) incubating said enzyme polypeptide with a copper-containing composition, thereby preparing a polysaccharide-oxidizing enzyme. 
     The said copper-containing composition may be selected from a composition containing one or more copper salts, such as sulphate or acetate copper salts. 
     Optionally, the said method may further comprise a step c) of removing an excess amount of copper (or salts thereof) from said composition comprising said enzyme polypeptide. 
     Methods for Identifying Polypeptides Belonging to the AAxx Protein Family 
     The inventors disclose herein a crystallographic structure of the PcAAxxB (JGI ID 1372210; GenBank ID #KY769370) catalytic module. They also disclose herein an extensive set of polysaccharide-oxidizing enzymes belonging to this novel enzyme family, along with reference protein sequences SEQ ID No 1, SEQ ID No 2 and SEQ ID No 3 For reference, SEQ ID No 3 corresponds to SEQ ID No 9 after peptide signal clevage; and SEQ ID No 8 corresponds to the cleaved peptide signal. 
     Accordingly, by combining the available structural information and the general consensus sequence derivable from said set of polysaccharide-oxidizing enzymes, it is thus also possible to determine any variant thereof having the desired polysaccharide-oxidizing activity. 
     In a non-limitative manner, program-implemented methods for determining a given set of engineered or native polypeptides belonging to a given family of polypeptides can be undergone in silico by homology or comparative modeling of protein three-dimensional structures based on an alignment of sequences and a given set of known related structures. Examples of programs suitable for homology and comparative modeling include:
     MODELLER© V.9.18 (se B. Webb, A. Sali. Comparative Protein Structure Modeling Using Modeller. Current Protocols in Bioinformatics, John Wiley &amp; Sons, Inc., 5.6.1-5.6.32, 2014);   I-TASSER V.5.1 (See J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8 (2015)) and   the SWISS-MODEL homology-modelling server (see Biasini M, Bienert S, Waterhouse A, Arnold K, Studer G, Schmidt T, Kiefer F, Cassarino T G, Bertoni M, Bordoli L, Schwede T (2014). SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information ( Nucleic Acids Research  2014 (1 Jul. 2014) 42 (W1): W252-W258).   

     Thus, according to one embodiment, the invention relates to a method for identifying polysaccharide-oxidizing enzymes, which comprises the steps of: 
     a1) providing one or more candidate polypeptides which may possess a polysaccharide-oxidizing activity; 
     a2) providing experimental coordinates of a reference polypeptide backbone and/or side chain, wherein said reference polypeptide backbone and/or side chain is a polypeptide comprising SEQ ID NO. 2 or SEQ ID NO 7, or a fragment thereof having a polysaccharide-oxidizing activity; 
     a3) providing a sequence alignment of the one or more candidate polypeptide with a reference polypeptide sequence possessing an amino acid identity of 20% or more with SEQ ID NO. 1, SEQ ID NO. 2, SEQ ID NO 3 or SEQ ID NO 7 by using the BLAST-P comparison method, characterized in that the said one or more candidate polypeptides possesses an E-value of 10 e 3  or less; 
     b) determining from a1), a2) and a3) the theorical coordinates of the one or more candidate polypeptide; 
     c) determining the root-mean-square deviation (RMSD) of the said theorical coordinates with the experimental coordinates of the reference polypeptide; 
     wherein an increased RMSD of the theorical coordinates, compared to the experimental coordinates, above a reference threshold indicates a lower probability of having a polysaccharide-oxidizing activity; 
     wherein a decreased RMSD of the theorical coordinates, compared to the experimental coordinates, below a reference threshold indicates a higher probability of having a polysaccharide-oxidizing activity. 
     d) optionally selecting the one or more candidate polypeptides of which the theorical coordinates define a copper-binding “histidine brace active site”, formed by two Histidine residues and a Tyrosine, one of those two Histidine residues being a N-terminal Histidine. 
     This invention also pertains to more complete compositions wherein the said compositions further comprise other enzymes contributing to the degradation of a polysaccharide-containing material, notably enzymes contributing to the degradation of a cellulose-containing material, and especially enzymes contributing to the degradation of lignocellulose-containing material. 
     In some embodiments of a polysaccharide-degrading composition as described herein, the said composition further comprises one or more polysaccharide-degrading enzymes selected in a group comprising cellulases, hemicellulases, ligninases, and carbohydrate oxidases. 
     Cellulases encompass endoglucanases and cellobiohydrolases and beta-glucosidases. 
     Hemicellulases encompass xylanases, mannanases, xylosidases, mannosidases, arabinofuranosidaes and esterases. 
     Ligninases encompass peroxidases, copper radical oxidases (e.g. laccases). 
     Carbohydrate oxidases encompass lytic polysaccharide monooxygenases and GMC oxidoreductases (e.g. glucose dehydrogenases, cellobiose dehydrogenases, . . . ). 
     According to some of these embodiments, the one or more cellulases comprised in a polysaccharide-degrading composition are selected in a group comprising exo-glucanases, endo-glucanases, cellobiohydrolases, cellulose phosphorylases, pectinases, pectate lyases, polygalacturonase, pectin esterases, cellobiose dehydrogenases, mannanases, arabino furanosidases, feruoyl esterases, arabinofuranosidases, fructofuranosidases, galactosidases, galactosidases, amylases, acetylxylan esterases, chitin deacetylases, chitinases, and glucosidases. 
     According to some of these embodiments, the one or more lytic polysaccharide monooxygenases comprised in a polysaccharide-degrading composition are selected in a group comprising AA9, AA10, AA11 and AA13. 
     According to some of these embodiments, wherein the said one or more other polysaccharide degrading enzymes are comprised in an enzyme preparation containing the said one or more other polysaccharide degrading enzymes. 
     According to some of these embodiments, the said enzyme preparation comprises one or more enzymes originating from one or more fungus organisms or one or more bacterial organisms. 
     According to some of these other embodiments, the said one or more fungus organism is selected in a group comprising fungi of the genus, but not limited to  Achlya, Acremonium, Aspergillus, Cephalosporium, Chrysosporm, Cochliobolus, Endothia, Fusarium, Gliocladium, Humicola, Hypocrea, Myceliophthora, Mucor, Neurospora, Penicillium, Pyricularia, Thielavia, Tolypocladium, Trichoderma, Podospora, Pycnoporus, Fusarium, Thermonospora, Hypocrea, Humnicola, Penicillim, Myceliophthora  and  Aspergillus.    
     According to some of these other embodiments, the said enzyme preparation comprises an enzyme extract from one or more fungus organisms or from one or more bacterial organisms. 
     According to some of these other embodiments, one or more of the said other polysaccharide-degrading enzymes are recombinant proteins. 
     The polysaccharide-oxidizing enzymes of the invention are further considered in the form of a kit, especially a kit for preparing a polysaccharide-oxidizing composition or a polysaccharide-degrading composition. 
     According to one embodiment, the invention relates to a kit for
         preparing a polysaccharide-oxidizing or polysaccharide-degrading composition;   oxidizing a polysaccharide;   preparing a sugar product from a polysaccharide-containing material   preparing a fermentation product from a polysaccharide-containing material; characterized in that it contains at least       

     (i) a polysaccharide-oxidizing enzyme wherein, when the said polysaccharide-oxidizing enzyme is compared to the reference polypeptide of SEQ ID NO. 1 by using the BLAST-P comparison method, (i) the said polysaccharide-oxidizing enzyme possesses an amino acid identity of 20% or more with the said reference polypeptide and (ii) the BLAST-P comparison method results in an E-value of 10 e −3  or less; and 
     (ii) at least another distinct enzyme selected from the group consisting of a polysaccharide-oxidizing or polysaccharide-degrading enzyme, as previously defined, which may thus include cellulases, hemicellulases, ligninases, and carbohydrate oxidases, which may thus include one or more lytic polysaccharide monooxygenases (LPMOs). 
     Said enzymes may also be in the form of polysaccharide-oxidizing or polysaccharide-degrading composition, as previously defined. 
     Alternatively, a kit of the invention may also comprise one or more yeast cells expressing a polysaccharide-oxidizing or polysaccharide-degrading enzyme, as previously defined. 
     Polysaccharide-Containing Material 
     As used herein, a polysaccharide containing material encompasses a substance or a composition comprising polysaccharide molecules. 
     The term “polysaccharide” is used in its conventional meaning, and designates polymeric carbohydrate molecules composed of long chains of monosaccharide units bound together by glycosidic linkages. On hydrolysis, polysaccharides release the constitutive monosaccharides or oligosaccharides. 
     Preferred polysaccharides according to the invention are plant-derived polysaccharides, and especially cellulose, such as cellulose contained in lignocellulose. 
     Other plant-derived polysaccharides which are particularly considered including xylans. Xylans belong to the group of hemicelluloses, and are polysaccharides made from units of xylose. 
     According to one embodiment, the polysaccharide-containing material is a material that comprises at least one (or a plurality of) polysaccharides selected from the group of cellulose, hemicellulose and lignin; which includes for instance any polysaccharide-containing material which contains at least 30 wt. % of cellulose and hemicellulose. For example, the polysaccharide-containing material may be a material such as birchwood cellulosic fibers, consisting of about 79% cellulose and about 21% xylan, as substrate. 
     The term “lignocellulose-containing material” used herein refers to material that primarily consists of cellulose, hemicellulose, and lignin. The term is synonymous with “lignocellulosic material”. Such material is often referred to as “biomass”. 
     Any lignocellulosic-containing material is contemplated according to the present invention. The lignocellulosic-containing material may be any material containing lignocellulose. In a preferred embodiment the lignocellulose-containing material contains at least 30 wt. %, preferably at least 50 wt. %, more preferably at least 70 wt. %, even more preferably at least 90 wt. % lignocellulose. It is to be understood that the lignocellulose-containing material may also comprise other constituents such as proteinaceous material, starch, sugars, such as fermentable sugars and/or un-fermentable sugars. 
     Lignocellulose-containing material is generally found, for example, in the stems, leaves, hulls, husks, and cobs of plants or leaves, branches, and wood of trees. Lignocellulose-containing material can also be, but is not limited to, herbaceous material, agricultural residues, forestry residues, municipal solid wastes, waste paper, and pulp and paper mill residues. It is understood herein that lignocellulose-containing material may be in the form of plant cell wall material containing lignin, cellulose, and hemi-cellulose in a mixed matrix. 
     In some particular embodiments, the lignocellulosic-containing material is a lignocellulosic biomass selected from the group consisting of grass, switch grass, cord grass, rye grass, reed canary grass, miscanthus, sugar-processing residues, sugarcane bagasse, agricultural wastes, rice straw, rice hulls, barley straw, corn cobs, cereal straw, wheat straw, canola straw, oat straw, oat hulls, corn fiber, stover, soybean stover, corn stover, forestry wastes, recycled wood pulp fiber, paper sludge, sawdust, hardwood, softwood, Agave, and combinations thereof. In a preferred embodiment the lignocellulose-containing material comprises one or more of corn stover, corn fiber, rice straw, pine wood, wood chips, poplar, bagasse, paper and pulp processing waste. 
     Preferably, the lignocellulosic-containing material is a lignocellulosic woody biomass. Other examples of lignocellulose-containing material include hardwood, such as poplar and birch, softwood, cereal straw, such as wheat straw, switchgrass, municipal solid waste, industrial organic waste, office paper, or mixtures thereof. 
     According to exemplary embodiments, the lignocellulosic-containing material is selected from pine, poplar and wheat straw. 
     Other Enzymes 
     As already specified herein, a polysaccharide-oxidizing composition according to the invention may comprise, in addition to one or more polysaccharide-oxidizing enzyme belonging to the enzyme family specifically identified by the inventors, also one or more other polysaccharide-oxidizing enzyme, such as one or more lytic polysaccharide monooxygenases (LPMOs). 
     As also already specified herein, a polysaccharide-degrading composition according to the invention may comprise, in addition to one or more polysaccharide-oxidizing enzyme belonging to the enzyme family specifically identified by the inventors, also one or more polysaccharide degrading enzyme, notably cellulolytic enzymes, which are also commonly termed cellulases. 
     The other enzymes may be simply combined or alternatively they may be contained in an enzyme mixture, such as a fungus-derived or a bacteria-derived enzyme mixture, for example a commercial fungus-derived enzyme mixture. 
     Cellulases that may be used in a polysaccharide degrading composition as described herein encompass exoglucanases, endoglucanases, cellobiohydrolases, cellulose phosphorylases, pectinases, pectate lyases, polygalacturonase, pectin esterases, cellobiose dehydrogenases, beta mannanases, arabinosidases, feruoyl esterases, arabino furanosidases, fructofuranosidases, alpha galactosidases, beta galactosidases, alpha amylases, acetylxylan esterases, chitin deacetylases, chitinases, and beta glucosidases. 
     In order to be efficient, degradation of cellulose may require several types of enzymes acting cooperatively. At least three categories of enzymes are often needed to convert cellulose into glucose: endoglucanases (EC 3.2.1.4) that cut the cellulose chains at random; cellobiohydrolases (EC 3.2.1.91) which cleave cellobiosyl units from the cellulose chain ends and beta-glucosidases (EC 3.2.1.21) that convert cellobiose and soluble cellodextrins into glucose. Among these three categories of enzymes involved in the biodegradation of cellulose, cellobiohydrolases are the key enzymes for the degradation of native crystalline cellulose. The term “cellobiohydrolases I” is defined herein as a cellulose 1,4-beta-cellobiosidase (also referred to as Exo-glucanase, Exo-cellobiohydrolase or 1,4-beta-cellobiohydrolase) activity, as defined in the enzyme class EC 3.2.1.91, which catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose and cellotetraose, by the release of cellobiose from the non-reducing ends of the chains. The definition of the term “cellobiohydrolase II activity” is identical, except that cellobiohydrolase II attacks from the reducing ends of the chains. 
     Cellulases preparation may further comprise a beta-glucosidase, such as a beta-glucosidase derived from a strain of the genus, but not limited to  Humicola, Trichoderma, Podospora, Pycnoporus, Fusarium, Thermonospora, Hvpocrea, Chrysosporium  and  Aspergillus.    
     Cellulases may be comprised in an enzyme mixture, which encompasses an enzyme mixture derived from  Trichoderma reesei.    
     Thus, cellulases which may be used in a polysaccharide-degrading composition as described herein may be derived from a fungal source, such as a strain of the genus  Trichoderma , preferably a strain of  Trichoderma reesei ; or a strain of the genus  Hunicola , such as a strain of  Hunicoa insolens ; or a strain of  Chrysosporium    
     Other useful enzymes encompass alpha-amylases; glucoamylases or another carbohydrate-source generating enzymes, such as beta-amylases, maltogenic amylases and/or alpha-glucosidases; proteases; or mixtures of two of more thereof. 
     Other useful enzymes are the lytic polysaccharide monoxygenases (LPMOs), and especially those LPMOs selected in a group comprising AA9, AA10, AA11 and AA13, which are described notably by Busk et al. (2015, BMC Genomics, Vol. 16: 368) and by Hemsworth et al. (2015, Trends in Biotechnology, Vol. 33 (12): 747-761). 
     Recombinant Yeast Expressing a Polysaccharide-Oxidizing Enzyme 
     In some embodiments of a polysaccharide-oxidizing composition or of a polysaccharide degrading composition as described herein, a polysaccharide-oxidizing enzyme belonging to the enzyme family specifically identified by the inventor may consist of a recombinant polypeptide, which encompasses a recombinant polypeptide produced in a yeast organism, as it is shown in the examples herein. 
     Thus, this invention also relates to a recombinant yeast cell expressing a polysaccharide-oxidizing enzyme as described in the present specification. 
     This invention concerns a recombinant yeast cell expressing a polysaccharide-oxidizing enzyme wherein, when the said polysaccharide-oxidizing enzyme is compared to the reference polypeptide of SEQ ID NO. 1 by using the BLAST-P comparison method, (i) the said polysaccharide-oxidizing enzyme possesses an amino acid identity of 20% or more with the said reference polypeptide and (ii) the BLAST-P comparison method results in an E-value of 10 e −3  or less. These polysaccharide-oxidizing enzymes are those which are described in the present specification. 
     In some embodiments, the yeast organism is selected in a group of yeast organisms comprising  Saccharomyces, Kluyveromyces, Candida, Pichia, Schizosaccharomyces, Hansenula, Klowcher, Schwanniomyces , and  Yarrowia . Yeast species as host cells may include, for example,  S cerevisiae. S. bulderi, S. barnetti, S. exiguus, S. uvarum, S. diastaticus, K. lactis, K., marxianus , or  K. fragilis . In some embodiments, the yeast is selected from the group consisting of  Saccharomyces cerevisiae, Schizzosacchamnyces pombe, Issatchenkia orientalis, Candida albicans, Candida mexicana, Pichia pastoris, Pichia mississippiensis, Pichia mexicana, Pichia stipitis. Pichia farinosa, Clavispora opuntiae, Clavispora lusitaniae, Yarrowia lipolytica, Hansenula polymorpha, Phaffia rhodozyma, Candida utilis, Arxula adeninivorans, Debaryomyces hansenii, Deburyomyces polymorphus, Schizosaccharomyces pombe, Hansenula polymorpha , and  Schwanniomyces occ dentalis.    
     A nucleic acid allowing the expression of a polysaccharide-oxidizing enzyme of interest is introduced in the genome of the selected yeast organism or is introduced as a non-integrated vector according to genetic engineering methods that are well known from the one skilled in the a. 
     A “vector,” e.g., a “plasmid” or “YAC” (yeast artificial chromosome) refers to an extrachromosomal element often carrying one or more genes that are not part of the central metabolism of the cell, and is usually in the form of a circular double-stranded DNA molecule. Such elements may be autonomously replicating sequences, genome integrating sequences, phage or nucleotide sequences, linear, circular, or supercoiled, of a single- or double-stranded DNA or RNA, derived from any source, in which a number of nucleotide sequences have been joined or recombined into a unique construction which is capable of introducing a promoter fragment and DNA sequence for a selected gene product along with appropriate 3′ untranslated sequence into a cell. Preferably, the plasmids or vectors of the present invention are stable and self-replicating. 
     An “expression vector” is a vector that is capable of directing the expression of genes to which it is operably associated. 
     Promoter” refers to a DNA fragment capable of controlling the expression of a coding sequence or functional RNA. In general, a coding region is located 3′ to a promoter. Promoters may be derived in their entirety from a native gene, or be composed of different elements derived from different promoters found in nature, or even comprise synthetic DNA segments. It is understood by those skilled in the art that different promoters may direct the expression of a gene in different tissues or cell types, or at different stages of development, or in response to different environmental or physiological conditions. 
     A coding region is “under the control” of transcriptional and translational control elements in a cell when RNA polymerase transcribes the coding region into mRNA, which is then trans-RNA spliced (if the coding region contains introns) and translated into the protein encoded by the coding region. 
     The present invention also relates to vectors which include a nucleic acid encoding a polysaccharide-oxidizing enzyme belonging to the family of enzymes specifically identified by the inventors, host cells, most preferably yeast host cells, which are genetically engineered with vectors of the invention and the production of the polysaccharide-oxidizing enzymes described herein by recombinant techniques. 
     Host cells, most preferably yeast host cells, are genetically engineered (transduced or transformed or transfected) with the vectors described above which may be, for example, a cloning vector or an expression vector. The vector may be, for example, in the form of a plasmid, a viral particle, a phage, etc. The engineered host cells can be cultured in conventional nutrient media modified as appropriate for activating promoters, selecting transformants or amplifying the genes of the present invention. The culture conditions, such as temperature, pH and the like, are those previously used with the host cell selected for expression, and will be apparent to the ordinarily skilled artisan. 
     The appropriate nucleic acid may be inserted into the vector by a variety of procedures. In general, the nucleic acid is inserted into an appropriate restriction endonuclease site(s) by procedures known in the art. Such procedures and others are deemed to be within the scope of those skilled in the art. 
     The nucleic acid is inserted in the expression vector is operatively associated with an appropriate expression control sequence(s) (promoter) to direct mRNA synthesis. Representative examples of such promoters are as follows: 
     The expression vector may also contain a ribosome binding site for translation initiation and/or a transcription terminator. The vector may also include appropriate sequences for amplifying expression, or may include additional regulatory regions. 
     The vector containing the appropriate nucleic acid, as well as an appropriate promoter or control sequence, may be employed to transform an appropriate host to permit the host to express the protein. 
     According to one embodiment, a yeast expressing a polysaccharide-oxidizing enzyme as previously defined may further express at least one additional enzyme selected from the group consisting of a polysaccharide-oxidizing or polysaccharide-degrading enzyme. 
     Methods of Producing Industrial Substances from Polysaccharide-Containing Material 
     The present invention also relates to a method for oxidizing a polysaccharide comprising a step of contacting one or more polysaccharides with a polysaccharide-oxidizing enzyme as described herein, or with a composition comprising the said polysaccharide-oxidizing enzyme. 
     In some embodiments of this method, the said one or more polysaccharides are comprised in a polysaccharide-containing biomass. 
     In some embodiments of this method, the said one or more polysaccharides are contained in a lignocellulosic-containing material. 
     This invention also pertains to methods for obtaining a sugar product from a polysaccharide-containing material, wherein the said methods comprise a step of hydrolyzing a polysaccharide-containing material by using a polysaccharide-oxidizing enzyme composition according to the invention, which includes by using an polysaccharide degrading composition as described in the present specification. 
     Thus, the present invention also concerns a method for oxidizing a polysaccharide comprising a step of contacting one or more polysaccharides with a polysaccharide-oxidizing enzyme as described in the present specification, or with a composition comprising the said polysaccharide-oxidizing enzyme. 
     This invention also relates to a method for the preparation of a sugar product from a polysaccharide-containing material comprising a step of treating the said polysaccharide-containing material in the presence of a polysaccharide degrading composition described in the present specification. 
     In preferred embodiments of these methods, the polysaccharide-containing materiel consists of a cellulose-containing material, such as preferably a lignocellulosic material, which encompasses lignocellulose. 
     This invention also provides a method for the preparation of a sugar product from a polysaccharide-containing material comprising the steps of:
         a) providing a polysaccharide-containing material,   b) subjecting the said polysaccharide-containing material to hydrolysis in the presence of a polysaccharide-degrading composition as described in the present specification, and   c) collecting the sugar product obtained at the end of step b).       

     General methods for the preparation of a sugar product from a polysaccharide-containing material which comprise a step of hydrolysing the said polysaccharide-containing material are already known in the art. Mom specifically, methods for the preparation of a sugar product, including glucose, f m a lignocellulosic-containing material are already known in the art. 
     In some embodiments of such methods, a lignocellulosic material is pretreated before the step of hydrolysis so as to increase the efficiency of the hydrolysis step. 
     Pre-Treatment of Lignocellulose 
     The structure of lignocellulose is not directly accessible to enzymatic hydrolysis. 
     Therefore, the lignocellulose-containing material has preferably to be pre-treated, e.g., by acid hydrolysis under adequate conditions of pressure and temperature, in order to break the lignin seal and disrupt the crystalline structure of cellulose. This causes solubilization of the hemicellulose and cellulose fractions. The cellulose and hemicellulose can then be hydrolyzed enzymatically such as described in the present specification, to convert the carbohydrate polymers into fermentable sugars 
     A pre-treatment step enhances the digestibility of lignocellulose and thus increases the efficiency of the hydrolysis step. 
     Methods for pretreating lignocellulose are well known in the art, which includes steps of chemical pretreatment, mechanical pretreatment and biological pretreatment. 
     When lignocellulose-containing material is pre-treated, degradation products that may inhibit enzymes and/or may be toxic to fermenting organisms are produced. These degradation products severely decrease both the hydrolysis and fermentation rate. Methods for pre-treating lignocellulose-containing material are well known in the art. The pre-treated lignocellulose degradation products include lignin degradation products, cellulose degradation products and hemicellulose degradation products. The pre-treated lignin degradation products may be phenolics in nature. 
     The lignocellulose-containing material may be pre-treated in any suitable way. Pre-treatment may be carried out before and/or during hydrolysis and/or fermentation. In a preferred embodiment the pre-treated material is hydrolyzed, preferably enzymatically, before and/or during fermentation. The goal of pre-treatment is to separate and/or release cellulose; hemicellulose and/or lignin and this way improve the rate of hydrolysis. Pre-treatment methods such as wet-oxidation and alkaline pre-treatment targets lignin, while dilute acid and auto-hydrolysis targets hemicellulose. Steam explosion is an example of a pre-treatment that targets cellulose. 
     According to the invention the pre-treatment applied in step (a) may be a conventional pre-treatment step using techniques well known in the art. 
     The lignocellulose-containing material may according to the invention be chemically, mechanically and/or biologically pre-treated before hydrolysis and/or fermentation. Mechanical treatment (often referred to as physical treatment) may be used alone or in combination with subsequent or simultaneous hydrolysis, especially enzymatic hydrolysis. 
     Preferably, chemical, mechanical and/or biological pre-treatment is carried out prior to the hydrolysis and/or fermentation. Alternatively, the chemical, mechanical and/or biological pre-treatment may be carried out simultaneously with hydrolysis, such as simultaneously with addition of one or more cellulase enzymes (cellulolytic enzymes), or other enzyme activities mentioned below, to release, e.g., fermentable sugars, such as glucose and/or maltose. 
     In an embodiment of the invention the pre-treated lignocellulose-containing material may be washed. However, washing is not mandatory and is in a preferred embodiment eliminated. 
     The term “chemical treatment” refers to any chemical pre-treatment which promotes the separation and/or release of cellulose, hemicellulose and/or lignin. Examples of suitable chemical pre-treatments include treatment with; for example, dilute acid, lime, alkaline, organic solvent, ammonia, sulfur dioxide, carbon dioxide. Further, wet oxidation and pH-controlled hydrothermolysis are also considered chemical pre-treatment. Pre-treatment methods using ammonia are notably described in the PCT applications WO 2006/110891, WO 2006/110899, WO 2006/110900, and WO 2006/110901. 
     Other examples of suitable pre-treatment methods are described by Schell et al., 2003, Appl. Biochem and Biotechn. Vol. 105-108: 69-85, and Mosier et al., 2005, Bioresource Technology 96: 673-686, and U.S. Publication No. 2002/0164730. 
     The term “mechanical pre-treatment” refers to any mechanical (or physical) treatment which promotes the separation and/or release of cellulose, hemicellulose and/or lignin from lignocellulose-containing material. For example, mechanical pre-treatment includes various types of milling, irradiation, steaming/steam explosion, and hydrothermolysis. 
     Mechanical pre-treatment includes comminution (mechanical reduction of the size). Comminution includes dry milling, wet milling and vibratory ball milling. Mechanical pre-treatment may involve high pressure and/or high temperature (steam explosion). 
     In some embodiments of a pretreatment step, the said step may combine chemical and mechanical pretreatment. 
     As used in the present invention the term “biological pre-treatment” refers to any biological pre-treatment which promotes the separation and/or release of cellulose, hemicellulose, and/or lignin from the lignocellulose-containing material. Biological pre-treatment techniques can involve applying lignin-solubilizing microorganisms (see, for example, Hsu, 1996, Pretreatment of biomass, in Handbook on Bioethanol: Production and Utilization, Wyman, ed., Taylor &amp; Francis, Washington, D.C., 179-212; Ghosh and Singh, 1993. Physicochemical and biological treatments for enzymatic/microbial conversion of lignocellulosic biomass, Adv. Appl. Microbiol. 39: 295-333; McMillan, 1994, Pretreating lignocellulosic biomass: a review, in Enzymatic Conversion of Biomass for Fuels Production, Himmel, Baker, and Overend, eds., ACS Symposium Series 566, American Chemical Society, Washington, D.C., chapter 15; Gong, Cao, Du, and Tsao, 1999, Ethanol production from renewable resources, in Advances in Biochemical Engineering/Biotechnology, Scheper, ed., Springer-Verlag Berlin Heidelberg, Germany, 65: 207-241; Olsson and Hahn-Hagerdal, 1996, Fermentation of lignocellulosic hydrolysates for ethanol production, Enz. Microb. Tech. 18: 312-331; and Vallander and Eriksson, 1990, Production of ethanol from lignocellulosic materials: State of the art, Adv. Biochem. Eng J Biotechnol. 42: 63-95). 
     Enzyme Hydrolysis 
     General methods of enzyme hydrolysis of a polysaccharide-containing material, including a cellulose-containing material, such as a lignocellulosic material, are well known for the one skilled in the art. Some of these methods are notably disclosed in the PCT applications WO 2015/165954, WO 20101080407, WO 2009026722, WO 2008/025165 and WO 2009:135898, as well as by Mohanram et al. (2013, Sustainable Chemical Processes, Vol. 1: 15-26), Van Dyk et al. (2012, Biotechnology Advances, Vol. 30: 1458-1480), Debeire et al. (2014, FEMS Microbiol Lett, Vol. 355: 116-123), Liao et al., 2011, Biotechnol J, Vol. 6: 1-9). Kumar et al. (2012, Final Technical Report, DSM Innovation, for the US Department of Energy under Award Number DE-FG36-08GO18079), Tucer et al., 2009, Turk J Biol, Vol. 33: 291-300). 
     Methods described herein comprise an enzymatic hydrolysis step. The enzymatic hydrolysis includes, but is not limited to, hydrolysis for the purpose of liquefaction of the feedstock and hydrolysis for the purpose of releasing sugar from the feedstock or both. In this step optionally pretreated and optionally washed lignocellulosic material is brought into contact with the enzyme composition according to the invention. Depending on the lignocellulosic material and the pretreatment, the different reaction conditions, e.g. temperature, enzyme dosage, hydrolysis reaction time and dry matter concentration, may be adapted by the skilled person in order to achieve a desired conversion of lignocellulose to sugar. Some indications are given hereafter. 
     In an embodiment the enzymatic hydrolysis comprises at least a liquefaction step wherein the lignocellulosic material is hydrolyzed in at least a first container, and a saccharification step wherein the liquefied lignocellulosic material is hydrolyzed in the at least first container and/or in at least a second container. Saccharification can be done in the same container as the liquefaction (i.e. the at least first container), it can also be done in a separate container (i.e. the at least second container). So, in the enzymatic hydrolysis of the processes according to the present invention liquefaction and saccharification may be combined. Alternatively, the liquefaction and saccharification may be separate steps. Liquefaction and saccharification may be performed at different temperatures, but may also be performed at a single temperature. In an embodiment the temperature of the liquefaction is higher than the temperature of the saccharification. 
     In some embodiments, liquefaction may be carried out at a temperature of 60-75° C. and saccharification may be carried out at a temperature of 50-65° C. 
     The enzymes used in the enzymatic hydrolysis may be added before and/or during the enzymatic hydrolysis. In case the enzymatic hydrolysis comprises a liquefaction step and saccharification step, additional enzymes may be added during and/or after the liquefaction step. The additional enzymes may be added before and/or during the saccharification step. Additional enzymes may also be added ater the saccharification step. 
     In some embodiments the hydrolysis is conducted at a temperature of 45° C. or more, 50° or more, 55° C. or more, 60° C. or more, 65° C. or more, or 70° C. or more. The high temperature during hydrolysis has many advantages, which include working at the optimum temperature of the enzyme composition, the reduction of risk of (bacterial) contamination, reduced viscosity, smaller amount of cooling water required, use of cooling water with a higher temperature, re-use of the enzymes and more. 
     For performing the step of hydrolysis, the total amount of enzymes added (herein also called enzyme dosage or enzyme load) is low. In an embodiment the amount of enzyme is 30 mg protein/g dry matter weight or lower, 20 mg protein/g dry matter or lower, 15 mg protein/g dry matter or lower, 10 mg protein/g dry matter or lower, or 5 mg protein/g dry matter or lower (expressed as protein in mg protein/g dry matter). 
     In an embodiment, the amount of polysaccharide-oxidizing enzyme added is 15 mg polysaccharide-oxidizing enzyme/g dry matter weight or lower, 10 mg polysaccharide-oxidizing enzyme/g dry matter weight or lower, 5 mg polysaccharide-oxidizing enzyme/g dry matter weight or lower or 1 mg enzyme g dry matter weight or lower (expressed as total of polysaccharide-oxidizing enzymes in mg enzyme/g dry matter). Low enzyme dosage is possible, since because of the activity and stability of the enzymes, it is possible to increase the hydrolysis reaction time. 
     In a further aspect of the invention, the hydrolysis reaction time is 5 hours or more, 10 hours or more, 20 hours or more, 40 hours or more, 50 hours or more, 60 hours or more, 70 hours or more, 80 hours or more, 90 hours or more, 100 hours or more, 120 hours or more, 130 h or more. In another aspect, the hydrolysis reaction time is 5 to 150 hours, 40 to 130 hours, 50 to 120 hours, 60 to 120 hours, 60 to 110 hours, 60 to 100 hours, 70 to 100 hours, 70 to 90 hours or 70 to 80 hours. Due to the stability of the enzyme composition longer hydrolysis reaction times are possible with corresponding higher sugar yields. 
     The pH during hydrolysis may be chosen by the skilled person. In a further aspect of the invention, the pH during the hydrolysis may be 3.0 to 6.4. The stable enzymes of the invention may have a broad pH range of up to 2 pH units, up to 3 pH units. up to 5 pH units. The optimum pH may lie within the limits of pH 2.0 to 8.0, 3.0 to 8.0, 3.5 to 7.0, 3.5 to 6.0, 3.5 to 5.0, 3.5 to 4.5, 4.0 to 4.5 or is about 4.2. 
     In a further aspect of the invention the hydrolysis step is conducted until 704% or more, 80% or more, 85% or more, 90% or more, 92% or more, 95% or more of available sugar in the lignocellulosic material is released. 
     In preferred embodiments, the hydrolysis step is performed in the presence of an electron donor compound and of oxygen. 
     An electron donor is a chemical entity, compound or composition that donates directly or indirectly electrons to another compound. It is a reducing agent that, by virtue of its donating electrons capacity, is itself oxidized in the process. Examples of electron donors are vitamin C (ascorbate), gallic acid, quinones. reduced glutathione, cysteine, low molecular weight lignin, high molecular weight lignin, ferulic acid, 3-hydroxyanthranilic acid, plant photosystem, cellobiose dehydrogenase, GMC oxidoreductase 
     So, electron donors are chemical entities which are involved in an oxidation reaction to generate or donate electrons. For the electron donor vitamin C, 1 molecule vitamin C donates 2 electrons. Some electron donors deliver only 1 clectron per molecule. Therefore, an electron donor used in the process of the invention is quantified in vitamin C (Vit C) equivalents on basis of the electrons that will be delivered. 
     Production of Industrially Useful Compounds 
     As it is readily understood by the one skilled in the art, a sugar product which is obtained by hydrolysis of a polysaccharide-containing material as described herein may be further processed for producing a variety of industrially useful compounds through well-known methods. Industrially useful compounds encompass ethanol and methanol. 
     Thus, this invention also pertains to a method for the preparation of a sugar product from a polysaccharide-containing material comprising a step of treating the said polysaccharide-containing material in the presence of a polysaccharide-oxidizing composition described in the present specification. 
     The use of a sugar product obtained by a method comprising a step of hydrolyzing a polysaccharide-containing material, such as a cellulose-containing material like lignocellulose are well known in the art. These methods most frequently comprises a step of fermenting the said sugar product, including fermenting glucose, so as to convert it into one or more industrially useful compounds, like ethanol or methanol. 
     Classically, a fermentation step is performed by using a fermenting organism, e.g. a yeast, may be fermented into a desired fermentation product, such as ethanol. Optionally the fermentation product may be recovered, e.g., by distillation. 
     Thus, in some embodiments, a lignocellulose-containing material is fermented by at least one fermenting organism capable of fermenting fermentable sugars, such as glucose, xylose, mannose, and galactose directly or indirectly into a desired fermentation product, according to any fermentation method which is well known from the one skilled in the art. 
     Subsequent to fermentation the fermentation product may be separated from the fermentation medium/broth. The medium/broth may be distilled to extract the fermentation product or the fermentation product may be extracted from the fermentation medium/broth by micro or membrane filtration techniques. Alternatively the fermentation product may be recovered by stripping. Recovery methods are well known in the art. 
     Such methods comprising a step of hydrolysing a lignocellulosic material and a step of fermenting the sugar product issued from hydrolysis may be used for producing any fermentation product. 
     Fermentation products encompass alcohols (e.g., ethanol, methanol, butanol); organic acids (e.g., citric acid, acetic acid, itaconic acid, lactic acid, gluconic acid); ketones (e.g., acetone); amino acids (e.g., glutamic acid); gases (e.g., H2 and CO2); antibiotics (e.g., penicillin and tetracycline); enzymes; vitamins (e.g., riboflavin, B12, beta-carotene); and hormones. 
     Thus, the present invention also concerns a method for the preparation of a fermentation product from a polysaccharide-containing material comprising the steps of:
         a) providing a polysaccharide-containing material,   b) subjecting the said polysaccharide-containing material to hydrolysis in the presence of a polysaccharide-degrading composition as described in the present specification, whereby a sugar product is obtained, and   c) fermenting the sugar product collected at step c), whereby a fermentation product is obtained.       

     In preferred embodiments of the method, the polysaccharide-containing material is a lignocellulosic material. 
     Fermentation methods are notably described by Gupta et al. (2016, Trends in Biochemical Sciences, Vol. 41(7): 633-645). 
     This invention is further illustrated, without in any way being limited to, the examples below. 
     EXAMPLES 
     A. Materials and Methods 
     A.1. Cloning and Production of Genes 
     The nucleotide sequence was synthesized with codon optimization for  P. pastoris  (GenScript, Piscataway, USA) and further inserted with the native signal sequence into a pPICZαA vector (Invitrogen, Cergy-Pontoise, France) using BstBI and XbaI restriction sites, in frame with the (His) 6  tag sequence at the C-terminus.  P. pastoris  strain X33 and the pPICZαA vector are components of the  P. pastoris  Easy Select Expression System (Invitrogen), all media and protocols are described in the manufacturer&#39;s manual (Invitrogen). 
     Transformation of competent  P. pastoris  X33 was performed by electroporation with PmeI-linearized pPICZαA recombinant plasmids as described in Bennati-Granier et al Biotechnol. Biofuels, 90 (2015)). Zeocin-resistant  P. pastoris  transformants were then screened for protein production. The best-producing transformant was grown in 2 l of BMGY containing 1 ml·l −1    Pichia  trace minerals 4 (PTM4) salts (2 g·l −1  CuSO 4 .5H 2 O, 3 g·l −1  MnSO 4 .H 2 O, 0.2 g·l 1  Na 2 MoO 4 .2H 2 O, 0.02 g·l 1 H 3 BO 3 , 0.5 g·l −1  CaSO 4 .2H 2 O, 0.5 g·l −1  CaCl 2 , 12.5 g·l −1  ZnSO 4 .7H 2 O, 22 g·l −1  FeSO 4 .7H 2 O, biotin 0.2 g·l −1 , H 2 SO 4  1 ml·l −1 ) in shaken flasks at 30° C. in an orbital shaker (200 rpm) to an OD 600  of 2 to 6. Cells were then transferred to 400 ml of BMMY containing 1 ml·l −1  of PTM4 salts at 20° C. in an orbital shaker (200 rpm) for 3 days, with supplementation with 3% (v/v) methanol every day. Purification was carried out as described in Bennati-Granier et al (2015) and concentrated protein was dialyzed against sodium acetate buffer, pH 5.2 and stored at 4° C. 
     A.2. Biochemical Analysis 
     10 μg of recombinant protein samples were loaded onto 10% SDS-PAGE gels (Thermo Fisher Scientific) and were detected by staining the gel with Coomassie Blue. The molecular mass under denaturating conditions was determined with reference standard proteins (PageRuler Prestained Protein Ladder, Thermo Fisher Scientific). Protein concentration was determined by using the Bradford assay (Bio-Rad, Mams-la-Coquette, France). 
     A.3. Amplex Red Method 
     A fluorimetric assay to assess the reactivity of the copper-containing proteins based on Amplex Red and horseradish peroxidase was used as described previously (Isaksen et al, Kittl et al, Bennati-Granier et al). Briefly, 10 μM to 40 μM of protein were incubated in 50 mM sodium acetate buffer pH 6.0 containing 50 μM Amplex Red (Sigma-Aldrich, Saint-Quentin Fallavir, France), 7.1 U·ml −1  horseradish peroxidase and 50 μM ascorbate as reductant in a final volume of 100 μl. The reaction was carried out at 30° C. for 30 minutes and fluorescence was detected using an excitation wavelength of 560 nm and an emission wavelength of 595 nm in a Tecan Infinite M200 plate reader (Tecan, Männedorf, Switzerland). 
     A.4. Saccharification Assays 
     Cleavage assays were performed using pretreated poplar (steam explosion under acidic conditions), Avicel and birchwood cellulose fibres. Assays were carried out in 1 ml final volume containing 5 mg poplar or 0.5% cellulose, 2.2 μM protein with 1 mM ascorbate in 50 mM sodium acetate buffer pH 5.2. The enzyme reactions were performed in 2-ml tubes and incubated in a thermomixer (Eppendorf, Montesson, France) at 45° C. and 800 rpm for 48 hours. At that time, 1 to 10 μg of  T. reesei  cocktail TR3012 was added to the mixture and samples were further incubated at 45° C. and 800 rpm. Samples were recovered at various time points, boiled at 100° C. for 10 min to stop the enzymatic reaction and then centrifuged at 14,000 rpm for 15 min at 4° C. to separate the soluble fraction from the remaining insoluble fraction before carbohydrate determination. The AA9 LPMO used in saccharification assays originated from  Podospora anserina  (PaLPMO9E). It was recombinantly expressed in  P. pastoris  as described in Bennati-Granier et al. 
     A.5. Analysis of Oxidized and Non-Oxidized Oligosaccharides 
     After saccharification, soluble sugar profiles were analysed using high-performance anion-exchange chromatography (HPAEC) coupled with pulsed amperometric detection (PAD) (ICS 3000; Dionex, Sunnyvale, USA) equipped with a carboPac PA-I analytical column (250×2 mm) and guard column. Samples and standards were injected into the HPAEC system and elution was carried out using a mufti-step gradient following the protocol described in Westereng et at. Briefly, the eluents were 0.1 M NaOH (eluent A) and 1 M NaOAc in 0.1 M NaOH (eluent B). Elution was performed at a constant flow rate of 0.25 ml/min at room temperature, using a linear gradient of 0-10% eluent B over 10 min, 10-30% eluent B over 25 min, and an exponential gradient of 30-100% eluent B in 5 min. The initial condition (100% eluent A) was then restored in 1 min and maintained for 9 min to recondition the column, 
     A.6. Production of  P.coccineus  AAxx LPMOs
 
Bioreactor production of the best-producing transformant was carried out in 1.3-L New Brunswick BioFlo® 15 fermentors (Eppendorf, Hamburg, Germany) following the  P. pastoris  fermentation process guidelines (Invitrogen) with some modifications. First, preculture was performed in 500 mL shake flask containing 100 mL of BMGY medium inoculated with a single colony from YPD agar (20 g·L−1 peptone, 10 g·L−1 yeast extract, 20 g·L−1 glucose, 20 g·L−1 agar) plate. Cells were grown for 16-18 h at 30° C. in a rotary shaker at 200 rpm which resulted in an OD 600 between 4 and 6. A 10% (v/v) inoculum was used to inoculate the bioreactor. The first phase consisted in a batch culture using 400 mL of basal salts medium composed of 40 g·L−1 glycerol; 26.7 mL·L−1H 3 PO4; 14.9 g·L−1 MgSO4.7H2O; 0.93 g·L−1 CaSO4.2H2O; 7.7 g·L−1 KCl; 4.13 g·L−1 KOH; 4.35 mL·L−1 PTM 1 salt solution (6 g·L−1 CuSO4.5H 2 O, 0.08 g·L−1 NaI, 3 g·L−1MnSO4.H 2 O, 0.2 g·L−1 Na2MoO4.2H2O, 0.02 g·L−1H3BO 3, 0.5 g·L−1 CoCl2, 20 g·L−1 ZnCl 2.7H2O, 0.2 g·L−1biotin, 5 mL·L−1H2SO 4, 65 g·L−1 FeSO4.7H 2 O). Batch phase was performed at 30° C., 400 rpm and pH was controlled at 5.0 with ammonium hydroxide (28% v/v). Dissolved oxygen was controlled at 20% with oxygen enrichment cascade (0-50%) using a gas flow rate at 0.5 v.v.m. As an antifoaming agent, 200 μl of Pluriol 8100 (BASF, Ludwigshafen. Germany) were added. After 20-24 h, phase 2 consisted of the simultaneous addition of 50 g of sorbitol and 0.5% of methanol (v/v) to the bioreactor until the yeast cells switched to methanol metabolism (i.e., 5 h later). During this phase, agitation was increased to 500 rpm and pH was slowly increased to pH 6 by addition of ammonium hydroxide (28% v/v). Finally, the induction phase (phase 3) was performed by adding a solution of methanol containing 12 mL·L−1 of PTM 1 salts (containing copper) by a fed-batch mode. The initial feed rate was 1.47 mL·h−1 and was increased after about 14 h of growth at a rate of 2.94 mL·h−1. The induction phase was carried out at 20° C. Dissolved oxygen was maintained to 20% via an agitation (400-800 rpm), gas flow (0.2-1 v.v.m.) and oxygen (0-50%) cascade. The induction phase was carried out for 144 h.
 
     A.7. Purification of PcAAxx LPMOs 
     The culture supernatants were recovered by pelleting the cells by centrifugation at 2,700 g for 5 min, 4° C. and filtered on 0.45 μm filters (Millipore, Molsheim, France) to remove any remaining cells. For (His) 6-tagged enzymes, the pH was adjusted to 7.8 and the supernatants were filtered once more on 0.2 μm filters and loaded onto 5 ml His Trap HP columns (GE healthcare, Buc, France) connected to an Akta Xpress system (GE healthcare). Prior to loading, the columns were equilibrated in Tris HCl 50 mM pH 7.8; NaCl 150 mM (buffer A). The loaded columns were then washed with 5 column volumes (CV) of 10 mM imidazole in buffer A, before the elution step with 5 CV of 150 mM imidazole in buffer A. Fractions containing the protein were pooled and concentrated onto a 3-kDa vivaspin concentrator (Sartorius, Pulaiseau, France) before loading onto a HiLoad 16/600 Superdex 75 Prep Grade column (GE Healthcare) and separated in acetate buffer 50 mM pH 5.2. Gel filtration analysis showed that both PcAAxx proteins are monomeric in solution even after copper loading. For enzymes without (His) 6-tag, salts contained in the culture media were diluted ten-fold in Tris-HCl 20 mM pH 8, then culture supernatants were concentrated onto a Pellicon-2 10-kDa cutoff cassette (Millipore) to a volume of approx. 200 mL and loaded onto a 20-mL High Prep DEAE column (GE Healthcare). Proteins were eluted using a linear gradient of 1 M NaCl (0 to 700 mM in 200 mL). Fractions were then analyzed by SDS PAGE and those containing the recombinant protein were pooled and concentrated. The concentrated proteins were then incubated with one-fold molar equivalent of CuSO4 overnight before separation on a HiLoad 16/600 Superdex 75 Prep Grade column in acetate buffer 50 mM pH 5.2. Protein-containing fractions were pooled and concentrated onto a 3-kDa vivaspin concentrator (Sartorius). 
     A.8. Deglycosylation Assays 
     To remove N-linked glycans, purified enzymes were treated with peptide EndoHf (New England Biolabs, Ipswich, Mass.) under denaturing conditions according to the manufacturer&#39;s instructions. Briefly, 10 μg of protein were incubated in 0.5% SDS and 40 mM DTT and heated for 10 min at 100° C. for complete denaturation. Denaturated samples were subsequently incubated with 1,500 units of peptide EndoHf in 50 mM sodium acetate pH 6.0 for 1 h at 37° C. Deglycosylated and control samples were analyzed by SDS-PAGE. 
     A.9. Crystallization of Purified PcAAxxB Protein 
     Purified PcAAxxB protein (JGI ID 1372210; GenBank ID #KY769370) was concentrated using 10-kDa polyethersulfone Vivaspin concentrators (Sartorius). The concentration was determined by measuring the A 280 nm using a NanoDrop ND-2000 instrument (Wilmington, Del., USA), All crystallization experiments were carried out at 20° C. by the sitting-drop vapour-diffusion method using %-well crystallization plates (Swissci) and a Mosquito® Crystal (TP labtech) crystallization robot. Reservoirs consisted of 40 μL of commercial screens and crystallization drops were prepared by mixing 100 nL reservoir solution with 100, 200 and 300 nL of protein solution. An initial hit was obtained after 1 week from a condition of the AmSO 4 screen (Qiagen) consisting of 2.4 M (NH4) 2SO4 and 0.1 M citric acid pH 4.0. This condition was further optimized to obtain diffraction-grade crystals by mixing protein solution at 28 mg·mL−1 with precipitant solution consisting of 2.4 M (NH 4) 2 SO4 and 0.1 M citric acid pH 4.4 at a volume ratio of 3:1. PcAAxxB crystals grew to dimensions of 0.15×0.15×0.05 mm in one week. Crystals belong to space group P41212 with cell axes 204×204×110 Å and two molecules per asymmetric unit. 
     A.10. Data Collection, Structure Determination and Refinement 
     Crystals of PcAAxxB were soaked for 5 min in a solution where 2.4 M (NH4)2SO4 of the mother liquor was replaced by 2.4 M Li2SO4 for the sake of cryoprotection prior to flash-cooling in liquid nitrogen. As X-ray fluorescence scans on native crystals did not reveal a significant presence of copper within the crystals, a heavy atom derivative was prepared by soaking the crystals in reservoir solution supplemented with 55 mM of the gadolinium complex gadoteridol prior to cryo-cooling. Native diffraction data were collected on beamline ID23-1, while a MAD dataset was collected on beamline ID30B at the European Synchrotron Radiation Facility (ESRF), Grenoble, France. Data were indexed and integrated in space group P41212 using XDS and subsequent processing steps were performed with the CCP4 software suite. Determination of the Gd3+ substructure and subsequent phasing combined with solvent flattening were carried out with SHELXC/D/E, using the SAD data collected at the Gd edge and leading to a pseudo-free correlation coefficient of 71.8%. Starting from experimental phases, an initial model comprising 526 residues (out of 584), was automatically built with Buccaneer and manually completed with Coot (44). This initial model was used for rigid body refinement followed by restrained refinement against native data with the program Ref mac. A random set of 5% of reflections was set aside for cross-validation purposes. Model quality was assessed with internal modules of Coot (44) and using the Molprobity server. Data collection and refinement statistics are summarized herebelow: 
     
       
         
           
               
             
               
                 TABLE 1 
               
             
            
               
                   
               
               
                 refinement statistics 
               
            
           
           
               
               
               
            
               
                   
                 Property 
                 Value 
               
               
                   
                   
               
               
                   
                 Space group 
                 P41212 
               
               
                   
                 Unit cell parameters 
                 203.75 203.75 110.59 
               
               
                   
                 a, b, c, α, β, γ 
                 90.00 90.00 90.00 
               
               
                   
                 Wavelength (Å) 
                 0.97625 
               
               
                   
                 Resolution range (Å) 
                 44.47-3.01 
               
               
                   
                 Completeness (%) (outer shell) 
                 98.5 (99.4) 
               
               
                   
                 Multiplicity (outer shell) 
                 8.3 (8.6) 
               
               
                   
                 &lt;I/σ (I)&gt; (outer shell) 
                 15.9 (2.0)  
               
               
                   
                 Rwork/Rfree 
                 0.23/0.24 
               
               
                   
                 Ramachandran statistics (%) 
                 100% 
               
               
                   
                 Favored &amp; Allowed 
               
               
                   
                   
               
            
           
         
       
     
     A.11. Bioinformatic Analysis of AAxx LPMOs 
       P. coccineus  AAxx sequences (Genbank ID KY769369 and KY769370) were compared to the NCBI non redundant sequences database using BlastP (29) in February 2016. Blast searches conducted with AAxx did not retrieve AA9s, AA10s, AA11s or AA13s with significant scores, and vice-versa. MUSCLE was used to perform multiple alignments. To avoid interference from the presence or absence of additional residues, the signal peptides and C-terminal extensions were moved. Bioinformatic analyses were performed on 286 fungal genomes sequenced and shared by JGI collaborators. Protein clusters are available thanks to the JGI (https://goo.gl/ZAa2NX) for each of these fungi. A phylogenetic tree has been inferred using 100 cleaned and merged alignment of proteins from selected clusters of proteins. Those clusters are present, as much as possible, in all fungi in 1 copy in order to maximize the score Σ1/n (with n, the number of copy in the genome). Sequences from clusters were aligned with Mafft, trimed with Gblocks and a phylogenetic tree was built with concatenation of alignments with Fasttree. Tree is displayed with Dendroscope and Bio::phylo. See  FIG. 6  for the phylogenetic tree and  FIGS. 8A &amp; 8B , corresponding to a consensus sequence of the catalytic module. 
     A.12. Copper-Loading Protocol 
     AAxx enzymes were copper loaded using copper salts (sulphate or acetate) during or after the purification. Proteins were incubated with ten molar equivalents of copper salts between two hours and overnight at 4° C. and excess of copper was removed using diafiltration with a 3-kDa centricon or with a gel filtration chromatography step. The presence of copper can be assessed by inductively coupled plasma mass spectrometry (ICP-MS), as described here after. 
     A.13. ICP/AIS Analysts 
     Prior to the analysis, samples are mineralized in a mixture containing ⅔ of nitric acid (Sigma-Aldrich, 65% Purissime) and ⅓ of hydrochloric acid (Fluka, 37%, Trace Select) at 120° C. The residues are diluted in ultra-pure water (2 mL) before ICP/MS analysis. The ICP-MS instrument is an ICAP Q (ThermoElectron, Les Ullis, France), equipped with a collision cell. The calibration curve is obtained by dilution of a certified multi-element solution (Sigma-Aldrich). Copper concentrations are determined using Plasmalab software (Thermo-Electron), at a mass of interest m/r=63. 
     Example 1: Recombinant Production or the Protein of SEQ ID NO.  1 , SEQ ID NO. 2 and SEQ ID NO. 3 
     Proteins of SEQ ID NO. 1, SEQ ID NO. 2 and SEQ ID NO. 3 were produced using the heterologous expression system  P. pastoris . The native signal peptide of each of the two proteins was conserved allowing for the Histidine residue to be at the N-term position after signal peptide processing in SEQ ID No 1, SEQ ID No 2 and SEQ ID No 3. 
     Electrophoretic analysis of the recombinant protein of SEQ ID NO. 1, the recombinant protein of SEQ ID NO. 2 and the recombinant protein of SEQ ID NO. 3 after purification revealed a single band ( FIG. 1 ). 
     Example 2: Production of Hydrogen Peroxide by the Proteins of SEQ ID NO. 1, SEQ ID NO. 2 and SEQ ID NO. 3 
     To assess the functionality of the proteins of SEQ ID NO. 1, SEQ ID NO. 2 and SEQ ID NO. 3, their capacity to produce H 2 O 2  in the presence of oxygen and electron donor (ascorbate) was evaluated. Significant H 2 O 2  production was detected ( FIG. 2 ). H 2 O 2  production was in the similar range as for LPMOs from other families described in the literature such as AA9 LPMOs from  P. anserina  (Bennati-Granier et al., 2015, Biotechnol Biofuels 8, 90). This assay reveals that the proteins of SEQ ID NO. 1, SEQ ID NO. 2 and SEQ ID NO. 3 bears a copper ion at the catalytic center as described for LPMOs. 
     Example 3: Polysaccharide-Degrading Activity of the Proteins of SEQ ID NO. 1 and SEQ ID NO. 2 in a Sequential Lignocellulose Degradation Assay 
     Degradation of lignocellulosic biomass with proteins of SEQ ID NO. 1 or SEQ ID NO. 2 and  T. reesei  cellulase cocktail were tested in sequential reactions. Pretreated poplar was first incubated with 2.2 μM (equivalent to 70 μg) protein of SEQ ID NO. 1 or 2.2 μM (equivalent to 70 μg) protein SEQ ID NO. 2 for 48 hours after which 10 μg of  T. reesei  TR3012 cellulase cocktail was added. The reactions were further incubated for 24 hours. Analyses of soluble sugar release using several methodologies (DNS assay, RTU assay and HPAEC) showed an improvement of released glucose and cello-oligosaccharides ( FIG. 3 ). Addition of increasing amount of the proteins of SEQ ID NO. 1 or SEQ ID NO. 2 resulted in proportional increase of glucose release ( FIG. 4 ). 
     Example 4: Polysaccharide-Degrading Activity of the Protein of SEQ ID NO. 1 and SEQ ID NO.2 in a Sequential Lignocellulose Degradation Assay in the Presence of AA9 LPMO 
     Degradation of lignocellulosic biomass with protein of SEQ ID NO. 1 and the AA9 LPMO was tested in sequential reactions. Pretreated poplar was first incubated with (i) Control medium, (ii) 2.2 μM (equivalent to 35 μg) protein of SEQ ID NO. 1, (iii) 2.2. μM of AA9 LPMO and (iv) 1.1 μM protein of SEQ ID NO. 1 and 1.1. μM of AA9 LPMO for 48 hours after which 10 μg of  T. reesei  TR3012 cellulase cocktail was added. The reactions were further incubated for 24 hours. Analyses of soluble sugar release using several methodologies (DNS assay, RTU assay and HPAEC) showed an improvement of released glucose and cello-oligosaccharides ( FIG. 5 ). 
     Example 5: A Crystal Structure of the PcAAxxB (JGI ID 1372210; GenBank ID #KY769370) Catalytic Module, Refined at a 3.0 Å Resolution, Reveals a Folded Core Protein and an Active Site Formed by a Canonical Histidine Brace Exposed at the Surface 
     PcAAxxB (#KY769370) was produced to high yield in  Pichia pastoris  and purified to homogeneity. 
     The structure of PcAAxxB was solved by multiple-wavelength anomalous dispersion data recorded at the gadolinium edge, and refined at 3.0 Å resolution. The core of the protein folds into a largely antiparallel P-sandwich, a fold globally similar to that seen in LPMOs from other families. 
     The active site of PcAAxxB constituted by His1, His99 and Tyr176 forming the canonical histidine brace is exposed at the surface ( FIG. 2B ). 
     In contrast to the flat substrate-binding surfaces observed in AA9 LPMOs, the PcAAxxB surface has a rippled shape with a clamp formed by two prominent surface loops, herein (see further herebelow) in a pdb (Protein Data Bank) format. Five N-glycans are attached in the crystal structure to PcAAxxB, through asparagine residues Asn13, Asn76, Asn133, Asn183 and Asn217. 
     The crystal structure further provides evidence of 10 cysteine residues involved in five disulfure bonds, at the following coupled positions: Cys67 &amp; Cys90; Cys109 &amp; Cys136; Cys153 &amp; Cys158; Cys160 &amp; Cys82; Cys202 &amp; Cys218. 
     The crystallized structure includes two molecules per assymetric unit. Chain A coordinates are disclosed herein (see further herebelow) in a pdb (Protein Data Bank) file format (see content of the crystal structure, further herebelow). Chain B, which is also part of the assymetric unit is not represented herein. 
     When viewed under PyMOL© Viewer 1.7.4.5 Edu (Schrodinger, LLC), boundaries of all the 6 β-sheets forming the core antiparallel β-sandwich consist of (by reference to SEQ ID No 2):
         from residue Phe53 to Glu64;   from residue Cys109 to Ala114;   from residue Thr128 to Asa133;   from residue Phe141 to Val146;   from residue Cys158 to Trp164;   from residue Met177 to Thr185.       

     The sequence SEQ ID No7 corresponds to the minimal fragment of SEQ ID No2 comprising the three amino acids which are involved in the copper-binding catalytic triade (which includes the N-terminal histidine residue); and further comprising the antiparallel P-sandwich, up to residue Thr185. 
     The following residues comprised within SEQ ID No 2 can be further positioned in the consensus sequence derived from  FIG. 8  as follows: 
     
       
         
           
               
             
               
                 TABLE 2A 
               
             
            
               
                   
               
               
                 Consensus Sequence and position in SEQ ID No2 
               
            
           
           
               
               
            
               
                   
                 Consensus Sequence 
               
            
           
           
               
               
               
               
               
               
               
               
            
               
                   
                 1 
                 20-35 
                 42-60 
                 78-151 
                 136-226 
                 146-241 
                 193-338 
               
               
                   
                   
               
            
           
           
               
               
               
               
               
               
               
               
            
               
                 Amino Acid 
                 H 
                 P 
                 P 
                 H 
                 W 
                 Y 
                 Y 
               
               
                 Position in 
                 1 
                 28 
                 47 
                 99 
                 164 
                 176 
                 246 
               
               
                 SEQ ID 2 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 2B 
               
             
            
               
                   
               
               
                 Consensus Sequence and position 
               
               
                 in SEQ ID No2 (Cysteine Residues) 
               
            
           
           
               
               
            
               
                   
                 Consensus Sequence 
               
            
           
           
               
               
               
               
               
               
               
            
               
                   
                 1 
                 20-35 
                 42-60 
                 78-151 
                 136-226 
                 146-241 
               
               
                   
                   
               
            
           
           
               
               
               
               
               
               
               
            
               
                 Amino Acid 
                 C 
                 C 
                 C 
                 C 
                 C 
                 C 
               
               
                 Position in 
                 153 
                 158 
                 160 
                 182 
                 202 
                 218 
               
               
                 SEQ ID 2 
               
               
                   
               
            
           
         
       
     
     Example 6: Saccharification Assay on Pretreated Biomass Including Poplar, Pine and Wheat Straw 
     We performed saccharification assays on pretreated biomass including poplar and pine using a  Trichoderma reesei  CL847 cocktail mainly composed of cellulases and xylanases. A boost of glucose release from poplar and pine was observed upon addition of any of the AAxx enzymes to the cocktail (see  FIG. 9 ). 
     When the reactions were conducted in the absence of a reductant the boost effect was also maintained, suggesting that one of the components from the biomass (e.g. lignin) may act as an electron donor. In a finding with important consequences for biorefinery use of woody biomass as feedstock, the  T. reesei  CL847 cocktail enriched in AA9 LPMO acting on cellulose was also boosted by PcAAxxA (of SEQ ID NO. 1), suggesting that AA9 and AAxx enzymes may act on different regions within the lignocellulosic matrix. 
     Because native AAxx members do not harbor any CBM module, we artificially attached a fungal CBM1 module targeting crystalline cellulose to PcAAxxAA. The resulting modular PcAAxA-CBA1 enzyme performed less efficiently than the catalytic module alone (data not shown), suggesting that AAxx enzymes do not require specific binding to the flat crystalline cellulose surface. 
     Overall, those experiments provide evidence that enzymes belonging to the AAxx family:
         remain efficient, as polysaccharide-oxidizing enzymes, for targeting a variety of material, and in particular a variety of lignocellulosic material; and   when used in polysaccharide-degrading compositions in combination with other enzymes, they may provide a surprisingly synergic activity, for instance by having a distinct attack on a lignocellulosic substrate, and especially on a xylan-comprising lignocellulosic substrate.       

     
       
         
           
               
               
            
               
                 SEQUENCE LISTING 
                   
               
               
                 SEQ ID NO. 1 
                   
               
               
                 HAAFWDKSMYGFNVTAQTFPYDNRPQVPLYNMTFDQWWFHGHKDYPPNEGDFFELPAGGEVNSIISCDKGATP 
                   
               
               
                   
               
               
                 FYESSPGGDSGYGSNSPCPGQPMSEYHTTGIDDVKGCCMAIAYKPDVNDVQPDDFVVFSCNSTCVWEMNTKFE 
               
               
                   
               
               
                 IPKLPACPEGGCHCAWFWIHSYDSGAEQIYMNGFKCKVTGDVGTQPLGKPAVPRRCGADPDHGKPDPTPGNCT 
               
               
                   
               
               
                 IGAKTPNYWYQREGNNMFEDTYDAPYYNPLYGFNDGAQNDIFMDGVIASLA 
               
               
                   
               
               
                 SEQ ID NO. 2 
                   
               
               
                 HIAFWHNSMYGFNVTEQTFPYDNRPVVPLQYMTFQEWWFHNHLDYPPHPGDFFDFPAGKAATAELACNKGATT 
                   
               
               
                   
               
               
                 WFNSSEGGNIQNGNDPCPGSPPSEYHTTGIDDVKGCAMAIAYESDVRKIKPEDFTVFSVNQTCVWYRFTDFQV 
               
               
                   
               
               
                 PERMPPCPPGGCHCAWFWIHSPDSGGEQIYMNGFQCNITGSTSHVPLAKPKVARRCGADPDHGRPDAVPGNCT 
               
               
                   
               
               
                 YGAKQPLYWLQKEGNNEFDDYIAPPFYNDLYNFKDGAQNDIFVDSYPDGI 
               
               
                   
               
               
                 SEQ ID NO. 3 
                   
               
               
                 HVAAFVKGMYCEGGPDPNNYNPNSNTPVNPLWDLPFEQWWMQADRGCNKAPPPDGASVALPAGGQFTVELAHN 
                   
               
               
                   
               
               
                 QAQTTLSFNGQFAGEWPDGQPHPENWSGPGSPPDCIQDDGAMHTNNQTMAAGTAWAISYNDDISKVTMDNLVV 
               
               
                   
               
               
                 FSVLEHTPWKRIATYDVPKDLPACPAGGCYCAWLWVPNGCGEPNMYMANYRCHVTNTTSTKQLAQAKPPTWCG 
               
               
                   
               
               
                 GDSSKCTKGAKQMIAWNQATGNNVQVPNGASPGYNINMGWAPGAQNDIFA 
               
               
                   
               
               
                 SEQ ID NO. 4 
                   
               
               
                 CACGCCGCGTTCTGGGACAAGTCCATGTACGGCTTCAACGTCACCGCACAGACCTTCCCCTACGACAACCGGC 
                   
               
               
                   
               
               
                 CCCAGGTTCCGCTCTACAACATGACTTTCGACCAATGGTGGTTCCACGGTCACAAAGACTACCCACCCAACGA 
               
               
                   
               
               
                 GGGCGATTTCTTCGAACTCCCTGCGGGTGGAGAGGTGAACAGCATCATCTCCTGCGATAAGGGTGCGACTCCG 
               
               
                   
               
               
                 TTCTACGAGTCGTCTCCGGGCGGAGATTCGGGCTATGGCAGCAACTCTCCTTGCCCCGGGCAGCCCATGTCCG 
               
               
                   
               
               
                 AGTACCACACGACGGGCATTGATGATGTCAAGGGCTSCTGCATGGCCATCGCGTACAAGCCCGATGTCAACGA 
               
               
                   
               
               
                 TGTGCAGCCAGACGACTTCGTGGTCTTCTCCTGCAACTCGACGTGCGTTTGGGAGATGAACACCAAGTTTGAG 
               
               
                   
               
               
                 ATCCCGAAGCTCCCTGCCTGCCCCGAAGGTGGTTGCCATTSCGCCTGGTTCTGGATTCACTCCTACGATAGCG 
               
               
                   
               
               
                 GTGCTGAGCAGATCTATATGAATGGTTTCAAGTGCAAAGTAACCGGCGACGTAGGCACTCAGCCTCTCGGCAA 
               
               
                   
               
               
                 GCCTGCCGTCCCGCGCAGGTGCGGTGCCGACCCTGATCACGGCAAGCCTGATCCTACTCCCGGTAATTGTACT 
               
               
                   
               
               
                 ATCGGGGCCAAGACGCCCATGTACTGGTACCAGCGGGAGGGTAACAACATGTTCGAAGACACTTATGACGCCC 
               
               
                   
               
               
                 CGTACTATAACCCACTCTACGGCTTCAACGATGGGGCGCAGAACGACATTTTCATGGATGGTGTCATCGCGTC 
               
               
                   
               
               
                 CCTCGCA 
               
               
                   
               
               
                 SEQ ID NO. 5 
                   
               
               
                 CACATCGCCTTCTGGCATAACAGCATGTACGGGTTCAATGTGACGGAACAGACGTTCCCTTACGACAACCGCC 
                   
               
               
                   
               
               
                 CCGTCGTCCCGCTTCAGTACATGACCTTCCAAGAATGGTGGTTCCACAACCACCTCGACTACCCGCCCCACCC 
               
               
                   
               
               
                 GGGCGACTTCTTCGACTTCCCGGCCGGCAAGGCCGCGACGGCGGAGCTCGCGTGCAACAAGGGCGCGACCACC 
               
               
                   
               
               
                 TGGTTCAACTCCTCCGAGGGCGGCAACATCCAGAACGGCAACGACCCGTGCCCGGGGAGCCCCCCGAGCGAGT 
               
               
                   
               
               
                 ACCACACGACGGGCATCGACGACGTGAAGGGCTGCGCGATGGCGATCGCGTACGAGTCCGACGTCAGGAAGAT 
               
               
                   
               
               
                 CAAGCCCGAGGACTTCACCGTCTTCAGCGTGAACCAGACGTGCGTCTGGTACCGCTTCACGGACTTCCAGGTC 
               
               
                   
               
               
                 CCCGAGCGCATGCCGCCGTGCCCTCCTGGCGGCTGTCACTGCGCGTGGTTCTGGATCCACTCGCCCGATAGCG 
               
               
                   
               
               
                 GCGGTGAGCAGATCTACATGAACGGCTTCCAGTGCAACATCACCGGCTCCACGTCCCACGTCCCGCTCGCAAA 
               
               
                   
               
               
                 GCCCAAAGTCGCTCGCCGCTGCGGTGCGGACCCGGACCACGGCAAGCCCGACGCCGTCCCCCGCAACTGCACA 
               
               
                   
               
               
                 TACGGTGCGAAGCAGCCCCTCTACTGGCTCCAGAAGGAGGGCAACAACGAGTTCGACGACTACATCGCGCCGC 
               
               
                   
               
               
                 CGTTCTACAACGACCTGTACAACTTCAAGGACGGCGCGCAGAACGACATCTTCGTCGACTCGTACCCCGACGG 
               
               
                   
               
               
                 CATC 
               
               
                   
               
               
                 SEQ ID NO. 6 
                   
               
               
                 ATGTTCTGGACGGTTCCCGTTACACTGGCTCTCGCCTCCGGGGCCTCTGCCCATGTTGCCGCCTTCGTGAAGG 
                   
               
               
                   
               
               
                 GCATGTACTGCGAGGGTGGCCCCGACCCTAACAACTACAACCCCAACTCCAACACTCCCGTCAACCCTCTCTG 
               
               
                   
               
               
                 GGATCTTCCTTTCGAGCAGTGGTGGATGCAGGCCGACCGTGGCTGCAACAAGGCTCCTCCTCCTGACGGTGCC 
               
               
                   
               
               
                 TCCGTTGCTCTGCCTGCCGGCGGCCAGTTCACTGTTGAGCTCGCCCACAACCAGGCCCAGACGACCTTATCCT 
               
               
                   
               
               
                 TCAATGGACAGTTCGCTGGCGAGTGGCCTGATGGCCAGCCTCACCCAGAGAACTGGAGCGGCCCCGGTAGCCC 
               
               
                   
               
               
                 CCCTGACTGCATCCAGGACGACGGTGCCATGCATACCAACAACCAGACAATGGCCGCTGGTACCGCTTGGGCC 
               
               
                   
               
               
                 ATTTCCTACAATGACGACATCTCCAAGGTGACCATGGACAACCTGGTTGTTTTCTCTGTCCTTGAGCACACCC 
               
               
                   
               
               
                 CTTGGAAGCGCATCGCCACCTATGATGTCCCCAAGGATCTCCCTGCTTGCCCTGCTGGCGGCTGCTACTGCGC 
               
               
                   
               
               
                 CTGGCTTTGGGTTCCCAACGGGTGCGGCGAGCCCAACATGTACATGGCCAACTACAGGTGCCATGTCACCAAC 
               
               
                   
               
               
                 ACCACCTCGACCAAGCAGCTTGCTCAAGCCAAGCCCCCCACCTGGTGTGGCGGTGACTCTTCCAAGTGCACCA 
               
               
                   
               
               
                 AGGGCGCTAAGCAGATGATTGCTTGGAACCAGGCCACAGGCAACAATGTCCAAGTTCCCAATGGCGCTTCCCC 
               
               
                   
               
               
                 CGGCTACACATCAACATGGGCTGGGCTCCCGGTGCTCAGAACGACATCTTCGCGTAG 
               
               
                   
               
               
                 SEQ ID NO. 7 
                   
               
               
                 HIAFWHNSMYGFNVTEQTFPYDNRPVVPLQYMTFQEWWFHNHLDYPPHPGDFFDFPAGKAATAELACNKGATT 
                   
               
               
                   
               
               
                 WFNSSEGGNIQNGNDPCPGSPPSEYHTTGIDDVKGCAMAIAYESDVRKIKPEDFTVFSVNQTCVWYRFTDFQV 
               
               
                   
               
               
                 PERMPPCPPGGCHCAWFWIHSPDSGGEQIYMNGFQCNIT 
               
               
                   
               
               
                 SEQ ID NO8 
                   
               
               
                 MFWTVPVTLALASGASA 
                   
               
               
                   
               
               
                 SEQ ID NO. 9 
                   
               
               
                 MFWTVPVTLALASGASAHVAAFVKGMYCEGGPDPNNYNPNSNTPVNPLWDLPFEQWWMQADRGCNKAPPPDGA 
                   
               
               
                   
               
               
                 SVALPAGGQFTVELAHNQAQTTLSFNGQFAGEWPDGQPHPENWSGFGSPPDCIQDDGAMHTNNQTMAAGTAWA 
               
               
                   
               
               
                 ISYNDDISKVTNDNLVVFSVLEHTPWKRIATYDVPKDLPACPAGGCYCAWLWVPNGCGEPNMYMANYRCHVTN 
               
               
                   
               
               
                 TTSTKQLAQAKPPTWCGGDSSKCTKGAKQMIAWNQATGNNVQVPNGASPGYNINMGWAPGAQNDIFA 
               
            
           
         
       
     
     
       
         
           
               
             
               
                   
               
               
                 CRYSTAL STRUCTURE OF AAxx (PcAAxxB) of SEQ ID No2 
               
               
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
               
               
            
               
                   
                 MODRES 
                 NAG 
                 A 
                 300 
                 NAG-b-D 
                 RENAME 
               
               
                   
                 MODRES 
                 NAG 
                 A 
                 301 
                 NAG-b-D 
                 RENAME 
               
               
                   
                 MODRES 
                 NAG 
                 A 
                 310 
                 NAG-b-D 
                 RENAME 
               
               
                   
                 MODRES 
                 NAG 
                 A 
                 311 
                 NAG-b-D 
                 RENAME 
               
               
                   
                 MODRES 
                 MAN 
                 A 
                 313 
                 MAN-a-D 
                 RENAME 
               
               
                   
                 MODRES 
                 MAN 
                 A 
                 314 
                 MAN-a-D 
                 RENAME 
               
               
                   
                 MODRES 
                 MAN 
                 A 
                 315 
                 MAN-a-D 
                 RENAME 
               
               
                   
                 MODRES 
                 NAG 
                 A 
                 320 
                 NAG-b-D 
                 RENAME 
               
               
                   
                 MODRES 
                 NAG 
                 A 
                 321 
                 NAG-b-D 
                 RENAME 
               
               
                   
                 MODRES 
                 MAN 
                 A 
                 323 
                 MAN-a-D 
                 RENAME 
               
               
                   
                 MODRES 
                 MAN 
                 A 
                 324 
                 MAN-a-D 
                 RENAME 
               
               
                   
                 MODRES 
                 NAG 
                 A 
                 330 
                 NAG-b-D 
                 RENAME 
               
               
                   
                 MODRES 
                 NAG 
                 A 
                 331 
                 NAG-b-D 
                 RENAME 
               
               
                   
                 MODRES 
                 MAN 
                 A 
                 333 
                 MAN-a-D 
                 RENAME 
               
               
                   
                 MODRES 
                 NAG 
                 A 
                 340 
                 NAG-b-D 
                 RENAME 
               
               
                   
                 MODRES 
                 NAG 
                 A 
                 341 
                 NAG-b-D 
                 RENAME 
               
               
                   
                 MODRES 
                 MAN 
                 A 
                 343 
                 MAN-a-D 
                 RENAME 
               
               
                   
                 MODRES 
                 MAN 
                 A 
                 344 
                 MAN-a-D 
                 RENAME 
               
               
                   
                 MODRES 
                 MAN 
                 A 
                 345 
                 MAN-a-D 
                 RENAME 
               
               
                   
                 MODRES 
                 MAN 
                 A 
                 346 
                 MAN-a-D 
                 RENAME 
               
               
                   
                   
               
            
           
           
               
               
               
               
               
               
               
               
               
            
               
                   
                 SSBOND 
                 1 
                 CYS 
                 A 
                 67 
                 CYS 
                 A 
                 90 
               
               
                   
                 SSBOND 
                 2 
                 CYS 
                 A 
                 109 
                 CYS 
                 A 
                 136 
               
               
                   
                 SSBOND 
                 3 
                 CYS 
                 A 
                 153 
                 CYS 
                 A 
                 158 
               
               
                   
                 SSBOND 
                 4 
                 CYS 
                 A 
                 160 
                 CYS 
                 A 
                 182 
               
               
                   
                 SSBOND 
                 5 
                 CYS 
                 A 
                 202 
                 CYS 
                 A 
                 218 
               
               
                   
                   
               
            
           
           
               
               
               
               
               
               
               
               
               
               
               
            
               
                   
                 LINKR 
                 C1 
                 NAG 
                 A 
                 300 
                 ND2 
                 ASN 
                 A 
                 13 
                 NAG-ASN 
               
               
                   
                 LINKR 
                 C1 
                 NAG 
                 A 
                 310 
                 ND2 
                 ASN 
                 A 
                 76 
                 NAG-ASN 
               
               
                   
                 LINKR 
                 C1 
                 NAG 
                 A 
                 320 
                 ND2 
                 ASN 
                 A 
                 133 
                 NAG-ASN 
               
               
                   
                 LINKR 
                 C1 
                 NAG 
                 A 
                 330 
                 ND2 
                 ASN 
                 A 
                 183 
                 NAG-ASN 
               
               
                   
                 LINKR 
                 C1 
                 NAG 
                 A 
                 340 
                 ND2 
                 ASN 
                 A 
                 217 
                 NAG-ASN 
               
               
                   
                 LINKR 
                   
                 NAG 
                 A 
                 300 
                   
                 NAG 
                 A 
                 301 
                 BETA1-4 
               
               
                   
                 LINKR 
                   
                 NAG 
                 A 
                 301 
                   
                 BMA 
                 A 
                 302 
                 BETA1-4 
               
               
                   
                 LINKR 
                   
                 NAG 
                 A 
                 310 
                   
                 NAG 
                 A 
                 311 
                 BETA1-4 
               
               
                   
                 LINKR 
                   
                 NAG 
                 A 
                 311 
                   
                 BMA 
                 A 
                 312 
                 BETA1-4 
               
               
                   
                 LINKR 
                   
                 BMA 
                 A 
                 312 
                   
                 MAN 
                 A 
                 313 
                 ALPHA1-6 
               
               
                   
                 LINKR 
                   
                 MAN 
                 A 
                 313 
                   
                 MAN 
                 A 
                 314 
                 ALPHA1-3 
               
               
                   
                 LINKR 
                   
                 BMA 
                 A 
                 312 
                   
                 MAN 
                 A 
                 315 
                 ALPHA1-3 
               
               
                   
                 LINKR 
                   
                 NAG 
                 A 
                 320 
                   
                 NAG 
                 A 
                 321 
                 BETA1-4 
               
               
                   
                 LINKR 
                   
                 NAG 
                 A 
                 321 
                   
                 BMA 
                 A 
                 322 
                 BETA1-4 
               
               
                   
                 LINKR 
                   
                 BMA 
                 A 
                 322 
                   
                 MAN 
                 A 
                 323 
                 ALPHA1-3 
               
               
                   
                 LINKR 
                   
                 BMA 
                 A 
                 322 
                   
                 MAN 
                 A 
                 324 
                 ALPHA1-6 
               
               
                   
                 LINKR 
                   
                 NAG 
                 A 
                 330 
                   
                 NAG 
                 A 
                 331 
                 BETA1-4 
               
               
                   
                 LINKR 
                   
                 NAG 
                 A 
                 331 
                   
                 BMA 
                 A 
                 332 
                 BETA1-4 
               
               
                   
                 LINKR 
                   
                 BMA 
                 A 
                 332 
                   
                 MAN 
                 A 
                 333 
                 ALPHA1-3 
               
               
                   
                 LINKR 
                   
                 NAG 
                 A 
                 340 
                   
                 NAG 
                 A 
                 341 
                 BETA1-4 
               
               
                   
                 LINKR 
                   
                 NAG 
                 A 
                 341 
                   
                 BMA 
                 A 
                 342 
                 BETA1-4 
               
               
                   
                 LINKR 
                   
                 BMA 
                 A 
                 342 
                   
                 MAN 
                 A 
                 343 
                 ALPHA1-3 
               
               
                   
                 LINKR 
                   
                 MAN 
                 A 
                 343 
                   
                 MAN 
                 A 
                 345 
                 ALPHA1-2 
               
               
                   
                 LINKR 
                   
                 BMA 
                 A 
                 342 
                   
                 MAN 
                 A 
                 344 
                 ALPHA1-6 
               
               
                   
                 LINKR 
                   
                 MAN 
                 A 
                 343 
                   
                 MAN 
                 A 
                 346 
                 ALPHA1-6 
               
               
                   
                   
               
            
           
           
               
               
               
               
               
               
               
               
               
               
               
            
               
                 CRYST1 
                 203.754 
                 203.754 
                 110.586 
                 90.00 
                 90.00 
                 90.00 
                 P 
                 41 
                 21 
                 2 
               
               
                   
               
            
           
           
               
               
               
               
               
               
            
               
                   
                 SCALE1 
                 0.004908 
                 0.000000 
                 0.000000 
                 0.00000 
               
               
                   
                 SCALE2 
                 −0.000000 
                 0.004908 
                 0.000000 
                 0.00000 
               
               
                   
                 SCALE3 
                 0.000000 
                 −0.000000 
                 0.009043 
                 0.00000 
               
               
                   
                   
               
            
           
           
               
               
               
               
               
               
               
               
               
               
               
               
            
               
                 ATOM 
                 1 
                 N 
                 HIS 
                 A 
                 1 
                 84.207 
                 23.023 
                 6.334 
                 1.00 
                 91.64 
                 N 
               
               
                 ATOM 
                 2 
                 CA 
                 HIS 
                 A 
                 1 
                 84.466 
                 23.579 
                 7.697 
                 1.00 
                 92.54 
                 C 
               
               
                 ATOM 
                 3 
                 CB 
                 HIS 
                 A 
                 1 
                 83.152 
                 23.732 
                 8.477 
                 1.00 
                 96.32 
                 C 
               
               
                 ATOM 
                 4 
                 CG 
                 HIS 
                 A 
                 1 
                 82.286 
                 24.858 
                 7.994 
                 1.00 
                 103.06 
                 C 
               
               
                 ATOM 
                 5 
                 ND1 
                 HIS 
                 A 
                 1 
                 81.800 
                 24.929 
                 6.705 
                 1.00 
                 107.25 
                 N 
               
               
                 ATOM 
                 6 
                 CE1 
                 HIS 
                 A 
                 1 
                 81.067 
                 26.021 
                 6.570 
                 1.00 
                 107.65 
                 C 
               
               
                 ATOM 
                 7 
                 NE2 
                 HIS 
                 A 
                 1 
                 81.051 
                 26.657 
                 7.728 
                 1.00 
                 107.39 
                 N 
               
               
                 ATOM 
                 8 
                 CD2 
                 HIS 
                 A 
                 1 
                 81.802 
                 25.948 
                 8.636 
                 1.00 
                 107.70 
                 C 
               
               
                 ATOM 
                 9 
                 C 
                 HIS 
                 A 
                 1 
                 85.475 
                 22.714 
                 8.468 
                 1.00 
                 89.46 
                 C 
               
               
                 ATOM 
                 10 
                 O 
                 HIS 
                 A 
                 1 
                 85.099 
                 21.813 
                 9.220 
                 1.00 
                 87.30 
                 O 
               
               
                 ATOM 
                 11 
                 N 
                 ILE 
                 A 
                 2 
                 86.758 
                 22.994 
                 8.247 
                 1.00 
                 85.02 
                 N 
               
               
                 ATOM 
                 12 
                 CA 
                 ILE 
                 A 
                 2 
                 87.864 
                 22.287 
                 8.897 
                 1.00 
                 82.47 
                 C 
               
               
                 ATOM 
                 13 
                 CB 
                 ILE 
                 A 
                 2 
                 88.504 
                 21.243 
                 7.951 
                 1.00 
                 82.74 
                 C 
               
               
                 ATOM 
                 14 
                 CG1 
                 ILE 
                 A 
                 2 
                 87.504 
                 20.143 
                 7.573 
                 1.00 
                 84.37 
                 C 
               
               
                 ATOM 
                 15 
                 CD1 
                 ILE 
                 A 
                 2 
                 87.087 
                 19.238 
                 8.714 
                 1.00 
                 84.11 
                 C 
               
               
                 ATOM 
                 16 
                 CG2 
                 ILE 
                 A 
                 2 
                 89.744 
                 20.610 
                 8.573 
                 1.00 
                 82.26 
                 C 
               
               
                 ATOM 
                 17 
                 C 
                 ILE 
                 A 
                 2 
                 88.930 
                 23.304 
                 9.288 
                 1.00 
                 82.66 
                 C 
               
               
                 ATOM 
                 18 
                 O 
                 ILE 
                 A 
                 2 
                 89.091 
                 24.331 
                 8.623 
                 1.00 
                 81.32 
                 O 
               
               
                 ATOM 
                 19 
                 N 
                 ALA 
                 A 
                 3 
                 89.659 
                 23.015 
                 10.364 
                 1.00 
                 83.36 
                 N 
               
               
                 ATOM 
                 20 
                 CA 
                 ALA 
                 A 
                 3 
                 90.744 
                 23.883 
                 10.810 
                 1.00 
                 83.72 
                 C 
               
               
                 ATOM 
                 21 
                 CB 
                 ALA 
                 A 
                 3 
                 90.229 
                 24.884 
                 11.825 
                 1.00 
                 85.46 
                 C 
               
               
                 ATOM 
                 22 
                 C 
                 ALA 
                 A 
                 3 
                 91.897 
                 23.099 
                 11.410 
                 1.00 
                 82.57 
                 C 
               
               
                 ATOM 
                 23 
                 O 
                 ALA 
                 A 
                 3 
                 91.711 
                 22.006 
                 11.943 
                 1.00 
                 82.43 
                 O 
               
               
                 ATOM 
                 24 
                 N 
                 PHE 
                 A 
                 4 
                 93.091 
                 23.676 
                 11.307 
                 1.00 
                 82.50 
                 N 
               
               
                 ATOM 
                 25 
                 CA 
                 PHE 
                 A 
                 4 
                 94.289 
                 23.131 
                 11.939 
                 1.00 
                 82.14 
                 C 
               
               
                 ATOM 
                 26 
                 CB 
                 PHE 
                 A 
                 4 
                 95.544 
                 23.679 
                 11.248 
                 1.00 
                 81.58 
                 C 
               
               
                 ATOM 
                 27 
                 CG 
                 PHE 
                 A 
                 4 
                 96.801 
                 23.534 
                 12.055 
                 1.00 
                 82.24 
                 C 
               
               
                 ATOM 
                 28 
                 CD1 
                 PHE 
                 A 
                 4 
                 97.531 
                 22.356 
                 12.025 
                 1.00 
                 84.74 
                 C 
               
               
                 ATOM 
                 29 
                 CE1 
                 PHE 
                 A 
                 4 
                 98.696 
                 22.226 
                 12.763 
                 1.00 
                 85.69 
                 C 
               
               
                 ATOM 
                 30 
                 CZ 
                 PHE 
                 A 
                 4 
                 99.145 
                 23.281 
                 13.536 
                 1.00 
                 86.18 
                 C 
               
               
                 ATOM 
                 31 
                 CE2 
                 PHE 
                 A 
                 4 
                 98.430 
                 24.463 
                 13.568 
                 1.00 
                 85.11 
                 C 
               
               
                 ATOM 
                 32 
                 CD2 
                 PHE 
                 A 
                 4 
                 97.267 
                 24.587 
                 12.829 
                 1.00 
                 82.90 
                 C 
               
               
                 ATOM 
                 33 
                 C 
                 PHE 
                 A 
                 4 
                 94.243 
                 23.540 
                 13.408 
                 1.00 
                 79.27 
                 C 
               
               
                 ATOM 
                 34 
                 O 
                 PHE 
                 A 
                 4 
                 94.223 
                 24.733 
                 13.713 
                 1.00 
                 78.92 
                 O 
               
               
                 ATOM 
                 35 
                 N 
                 TRP 
                 A 
                 5 
                 94.214 
                 22.556 
                 14.308 
                 1.00 
                 76.19 
                 N 
               
               
                 ATOM 
                 36 
                 CA 
                 TRP 
                 A 
                 5 
                 94.078 
                 22.815 
                 15.748 
                 1.00 
                 73.59 
                 C 
               
               
                 ATOM 
                 37 
                 CB 
                 TRP 
                 A 
                 5 
                 92.972 
                 21.947 
                 16.342 
                 1.00 
                 71.23 
                 C 
               
               
                 ATOM 
                 38 
                 CG 
                 TRP 
                 A 
                 5 
                 91.616 
                 22.342 
                 15.888 
                 1.00 
                 71.66 
                 C 
               
               
                 ATOM 
                 39 
                 CD1 
                 TRP 
                 A 
                 5 
                 90.794 
                 21.643 
                 15.057 
                 1.00 
                 71.88 
                 C 
               
               
                 ATOM 
                 40 
                 NE1 
                 TRP 
                 A 
                 5 
                 89.622 
                 22.333 
                 14.860 
                 1.00 
                 73.14 
                 N 
               
               
                 ATOM 
                 41 
                 CE2 
                 TRP 
                 A 
                 5 
                 89.674 
                 23.506 
                 15.565 
                 1.00 
                 73.24 
                 C 
               
               
                 ATOM 
                 42 
                 CD2 
                 TRP 
                 A 
                 5 
                 90.919 
                 23.547 
                 16.223 
                 1.00 
                 72.48 
                 C 
               
               
                 ATOM 
                 43 
                 CE3 
                 TRP 
                 A 
                 5 
                 91.226 
                 24.656 
                 17.018 
                 1.00 
                 72.79 
                 C 
               
               
                 ATOM 
                 44 
                 CZ3 
                 TRP 
                 A 
                 5 
                 90.291 
                 25.675 
                 17.132 
                 1.00 
                 73.08 
                 C 
               
               
                 ATOM 
                 45 
                 CH2 
                 TRP 
                 A 
                 5 
                 89.059 
                 25.606 
                 16.466 
                 1.00 
                 74.22 
                 C 
               
               
                 ATOM 
                 46 
                 CZ2 
                 TRP 
                 A 
                 5 
                 88.733 
                 24.533 
                 15.679 
                 1.00 
                 74.18 
                 C 
               
               
                 ATOM 
                 47 
                 C 
                 TRP 
                 A 
                 5 
                 95.360 
                 22.586 
                 16.533 
                 1.00 
                 75.33 
                 C 
               
               
                 ATOM 
                 48 
                 O 
                 TRP 
                 A 
                 5 
                 95.922 
                 21.491 
                 16.518 
                 1.00 
                 74.09 
                 O 
               
               
                 ATOM 
                 49 
                 N 
                 HIS 
                 A 
                 6 
                 95.804 
                 23.632 
                 17.227 
                 1.00 
                 80.24 
                 N 
               
               
                 ATOM 
                 50 
                 CA 
                 HIS 
                 A 
                 6 
                 96.984 
                 23.570 
                 18.089 
                 1.00 
                 80.86 
                 C 
               
               
                 ATOM 
                 51 
                 CB 
                 HIS 
                 A 
                 6 
                 98.257 
                 23.467 
                 17.251 
                 1.00 
                 78.51 
                 C 
               
               
                 ATOM 
                 52 
                 CG 
                 HIS 
                 A 
                 6 
                 99.432 
                 22.941 
                 18.008 
                 1.00 
                 76.30 
                 C 
               
               
                 ATOM 
                 53 
                 ND1 
                 HIS 
                 A 
                 6 
                 100.512 
                 23.725 
                 18.351 
                 1.00 
                 76.28 
                 N 
               
               
                 ATOM 
                 54 
                 CE1 
                 HIS 
                 A 
                 6 
                 101.395 
                 22.993 
                 19.006 
                 1.00 
                 76.89 
                 C 
               
               
                 ATOM 
                 55 
                 NE2 
                 HIS 
                 A 
                 6 
                 100.923 
                 21.763 
                 19.104 
                 1.00 
                 76.64 
                 N 
               
               
                 ATOM 
                 56 
                 CD2 
                 HIS 
                 A 
                 6 
                 99.699 
                 21.704 
                 18.485 
                 1.00 
                 74.93 
                 C 
               
               
                 ATOM 
                 57 
                 C 
                 HIS 
                 A 
                 6 
                 97.027 
                 24.823 
                 18.964 
                 1.00 
                 83.70 
                 C 
               
               
                 ATOM 
                 58 
                 O 
                 HIS 
                 A 
                 6 
                 96.542 
                 25.872 
                 18.553 
                 1.00 
                 87.03 
                 O 
               
               
                 ATOM 
                 59 
                 N 
                 ASN 
                 A 
                 7 
                 97.613 
                 24.720 
                 20.156 
                 1.00 
                 84.93 
                 N 
               
               
                 ATOM 
                 60 
                 CA 
                 ASN 
                 A 
                 7 
                 97.683 
                 25.864 
                 21.083 
                 1.00 
                 82.64 
                 C 
               
               
                 ATOM 
                 61 
                 CB 
                 ASN 
                 A 
                 7 
                 98.139 
                 25.415 
                 22.476 
                 1.00 
                 82.43 
                 C 
               
               
                 ATOM 
                 62 
                 CG 
                 ASN 
                 A 
                 7 
                 99.559 
                 24.883 
                 22.488 
                 1.00 
                 85.12 
                 C 
               
               
                 ATOM 
                 63 
                 OD1 
                 ASN 
                 A 
                 7 
                 100.174 
                 24.686 
                 21.440 
                 1.00 
                 88.15 
                 O 
               
               
                 ATOM 
                 64 
                 ND2 
                 ASN 
                 A 
                 7 
                 100.089 
                 24.647 
                 23.682 
                 1.00 
                 87.40 
                 N 
               
               
                 ATOM 
                 65 
                 C 
                 ASN 
                 A 
                 7 
                 98.571 
                 27.017 
                 20.592 
                 1.00 
                 80.24 
                 C 
               
               
                 ATOM 
                 66 
                 O 
                 ASN 
                 A 
                 7 
                 98.520 
                 28.120 
                 21.138 
                 1.00 
                 81.89 
                 O 
               
               
                 ATOM 
                 67 
                 N 
                 SER 
                 A 
                 8 
                 99.379 
                 26.753 
                 19.568 
                 1.00 
                 76.92 
                 N 
               
               
                 ATOM 
                 68 
                 CA 
                 SER 
                 A 
                 8 
                 100.251 
                 27.760 
                 18.971 
                 1.00 
                 76.31 
                 C 
               
               
                 ATOM 
                 69 
                 CB 
                 SER 
                 A 
                 8 
                 101.521 
                 27.099 
                 18.439 
                 1.00 
                 78.16 
                 C 
               
               
                 ATOM 
                 70 
                 OG 
                 SER 
                 A 
                 8 
                 101.219 
                 26.179 
                 17.403 
                 1.00 
                 76.69 
                 O 
               
               
                 ATOM 
                 71 
                 C 
                 SER 
                 A 
                 8 
                 99.578 
                 28.518 
                 17.828 
                 1.00 
                 74.65 
                 C 
               
               
                 ATOM 
                 72 
                 O 
                 SER 
                 A 
                 8 
                 100.198 
                 29.385 
                 17.213 
                 1.00 
                 74.69 
                 O 
               
               
                 ATOM 
                 73 
                 N 
                 MET 
                 A 
                 9 
                 98.324 
                 28.191 
                 17.536 
                 1.00 
                 73.77 
                 N 
               
               
                 ATOM 
                 74 
                 CA 
                 MET 
                 A 
                 9 
                 97.611 
                 28.834 
                 16.441 
                 1.00 
                 74.84 
                 C 
               
               
                 ATOM 
                 75 
                 CB 
                 MET 
                 A 
                 9 
                 96.458 
                 27.949 
                 15.954 
                 1.00 
                 74.96 
                 C 
               
               
                 ATOM 
                 76 
                 CG 
                 MET 
                 A 
                 9 
                 95.228 
                 27.964 
                 16.847 
                 1.00 
                 74.10 
                 C 
               
               
                 ATOM 
                 77 
                 SD 
                 MET 
                 A 
                 9 
                 94.042 
                 26.680 
                 16.421 
                 1.00 
                 74.41 
                 S 
               
               
                 ATOM 
                 78 
                 CE 
                 MET 
                 A 
                 9 
                 93.364 
                 27.372 
                 14.914 
                 1.00 
                 77.74 
                 C 
               
               
                 ATOM 
                 79 
                 C 
                 MET 
                 A 
                 9 
                 97.063 
                 30.188 
                 16.849 
                 1.00 
                 75.28 
                 C 
               
               
                 ATOM 
                 80 
                 O 
                 MET 
                 A 
                 9 
                 96.799 
                 30.440 
                 18.024 
                 1.00 
                 83.04 
                 O 
               
               
                 ATOM 
                 81 
                 N 
                 TYR 
                 A 
                 10 
                 96.888 
                 31.053 
                 15.859 
                 1.00 
                 74.31 
                 N 
               
               
                 ATOM 
                 82 
                 CA 
                 TYR 
                 A 
                 10 
                 96.248 
                 32.339 
                 16.074 
                 1.00 
                 74.32 
                 C 
               
               
                 ATOM 
                 83 
                 CB 
                 TYR 
                 A 
                 10 
                 96.636 
                 33.330 
                 14.973 
                 1.00 
                 72.98 
                 C 
               
               
                 ATOM 
                 84 
                 CG 
                 TYR 
                 A 
                 10 
                 98.026 
                 33.895 
                 15.150 
                 1.00 
                 71.66 
                 C 
               
               
                 ATOM 
                 85 
                 CD1 
                 TYR 
                 A 
                 10 
                 99.150 
                 33.108 
                 14.941 
                 1.00 
                 72.01 
                 C 
               
               
                 ATOM 
                 86 
                 CE1 
                 TYR 
                 A 
                 10 
                 100.426 
                 33.619 
                 15.115 
                 1.00 
                 72.90 
                 C 
               
               
                 ATOM 
                 87 
                 CZ 
                 TYR 
                 A 
                 10 
                 100.586 
                 34.935 
                 15.497 
                 1.00 
                 73.32 
                 C 
               
               
                 ATOM 
                 88 
                 OH 
                 TYR 
                 A 
                 10 
                 101.845 
                 35.457 
                 15.668 
                 1.00 
                 75.71 
                 O 
               
               
                 ATOM 
                 89 
                 CE2 
                 TYR 
                 A 
                 10 
                 99.486 
                 35.738 
                 15.707 
                 1.00 
                 73.41 
                 C 
               
               
                 ATOM 
                 90 
                 CD2 
                 TYR 
                 A 
                 10 
                 98.216 
                 35.216 
                 15.535 
                 1.00 
                 73.15 
                 C 
               
               
                 ATOM 
                 91 
                 C 
                 TYR 
                 A 
                 10 
                 94.740 
                 32.106 
                 16.111 
                 1.00 
                 75.52 
                 C 
               
               
                 ATOM 
                 92 
                 O 
                 TYR 
                 A 
                 10 
                 94.209 
                 31.290 
                 15.354 
                 1.00 
                 77.48 
                 O 
               
               
                 ATOM 
                 93 
                 N 
                 GLY 
                 A 
                 11 
                 94.059 
                 32.813 
                 17.004 
                 1.00 
                 76.98 
                 N 
               
               
                 ATOM 
                 94 
                 CA 
                 GLY 
                 A 
                 11 
                 92.618 
                 32.658 
                 17.176 
                 1.00 
                 77.07 
                 C 
               
               
                 ATOM 
                 95 
                 C 
                 GLY 
                 A 
                 11 
                 92.251 
                 31.299 
                 17.739 
                 1.00 
                 77.32 
                 C 
               
               
                 ATOM 
                 96 
                 O 
                 GLY 
                 A 
                 11 
                 91.217 
                 30.735 
                 17.388 
                 1.00 
                 78.34 
                 O 
               
               
                 ATOM 
                 97 
                 N 
                 PHE 
                 A 
                 12 
                 93.100 
                 30.779 
                 18.620 
                 1.00 
                 76.88 
                 N 
               
               
                 ATOM 
                 98 
                 CA 
                 PHE 
                 A 
                 12 
                 92.893 
                 29.466 
                 19.228 
                 1.00 
                 77.53 
                 C 
               
               
                 ATOM 
                 99 
                 CB 
                 PHE 
                 A 
                 12 
                 94.060 
                 29.150 
                 20.169 
                 1.00 
                 79.12 
                 C 
               
               
                 ATOM 
                 100 
                 CG 
                 PHE 
                 A 
                 12 
                 93.945 
                 27.823 
                 20.868 
                 1.00 
                 82.77 
                 C 
               
               
                 ATOM 
                 101 
                 CD1 
                 PHE 
                 A 
                 12 
                 93.956 
                 26.638 
                 20.146 
                 1.00 
                 83.25 
                 C 
               
               
                 ATOM 
                 102 
                 CE1 
                 PHE 
                 A 
                 12 
                 93.863 
                 25.415 
                 20.785 
                 1.00 
                 83.58 
                 C 
               
               
                 ATOM 
                 103 
                 CZ 
                 PHE 
                 A 
                 12 
                 93.771 
                 25.363 
                 22.166 
                 1.00 
                 84.84 
                 C 
               
               
                 ATOM 
                 104 
                 CE2 
                 PHE 
                 A 
                 12 
                 93.768 
                 26.534 
                 22.900 
                 1.00 
                 85.08 
                 C 
               
               
                 ATOM 
                 105 
                 CD2 
                 PHE 
                 A 
                 12 
                 93.861 
                 27.755 
                 22.253 
                 1.00 
                 85.04 
                 C 
               
               
                 ATOM 
                 106 
                 C 
                 PHE 
                 A 
                 12 
                 91.560 
                 29.370 
                 19.972 
                 1.00 
                 78.05 
                 C 
               
               
                 ATOM 
                 107 
                 O 
                 PHE 
                 A 
                 12 
                 90.881 
                 28.343 
                 19.906 
                 1.00 
                 79.95 
                 O 
               
               
                 ATOM 
                 108 
                 N 
                 ASN 
                 A 
                 13 
                 91.187 
                 30.445 
                 20.664 
                 1.00 
                 79.85 
                 N 
               
               
                 ATOM 
                 109 
                 CA 
                 ASN 
                 A 
                 13 
                 89.955 
                 30.483 
                 21.455 
                 1.00 
                 80.66 
                 C 
               
               
                 ATOM 
                 110 
                 CB 
                 ASN 
                 A 
                 13 
                 90.259 
                 31.013 
                 22.860 
                 1.00 
                 82.92 
                 C 
               
               
                 ATOM 
                 111 
                 CG 
                 ASN 
                 A 
                 13 
                 91.025 
                 30.020 
                 23.719 
                 1.00 
                 85.75 
                 C 
               
               
                 ATOM 
                 112 
                 OD1 
                 ASN 
                 A 
                 13 
                 91.179 
                 28.849 
                 23.368 
                 1.00 
                 86.69 
                 O 
               
               
                 ATOM 
                 113 
                 ND2 
                 ASN 
                 A 
                 13 
                 91.509 
                 30.497 
                 24.869 
                 1.00 
                 88.38 
                 N 
               
               
                 ATOM 
                 114 
                 C 
                 ASN 
                 A 
                 13 
                 88.835 
                 31.321 
                 20.839 
                 1.00 
                 80.10 
                 C 
               
               
                 ATOM 
                 115 
                 O 
                 ASN 
                 A 
                 13 
                 87.829 
                 31.582 
                 21.499 
                 1.00 
                 79.99 
                 O 
               
               
                 ATOM 
                 116 
                 N 
                 VAL 
                 A 
                 14 
                 88.996 
                 31.732 
                 19.582 
                 1.00 
                 80.60 
                 N 
               
               
                 ATOM 
                 117 
                 CA 
                 VAL 
                 A 
                 14 
                 87.972 
                 32.528 
                 18.898 
                 1.00 
                 79.17 
                 C 
               
               
                 ATOM 
                 118 
                 CB 
                 VAL 
                 A 
                 14 
                 88.473 
                 33.066 
                 17.539 
                 1.00 
                 78.29 
                 C 
               
               
                 ATOM 
                 119 
                 CG1 
                 VAL 
                 A 
                 14 
                 87.331 
                 33.669 
                 16.731 
                 1.00 
                 78.86 
                 C 
               
               
                 ATOM 
                 120 
                 CG2 
                 VAL 
                 A 
                 14 
                 89.567 
                 34.101 
                 17.751 
                 1.00 
                 79.23 
                 C 
               
               
                 ATOM 
                 121 
                 C 
                 VAL 
                 A 
                 14 
                 86.715 
                 31.690 
                 18.685 
                 1.00 
                 79.96 
                 C 
               
               
                 ATOM 
                 122 
                 O 
                 VAL 
                 A 
                 14 
                 86.795 
                 30.543 
                 18.244 
                 1.00 
                 82.35 
                 O 
               
               
                 ATOM 
                 123 
                 N 
                 THR 
                 A 
                 15 
                 85.562 
                 32.271 
                 19.007 
                 1.00 
                 81.16 
                 N 
               
               
                 ATOM 
                 124 
                 CA 
                 THR 
                 A 
                 15 
                 84.278 
                 31.594 
                 18.853 
                 1.00 
                 83.25 
                 C 
               
               
                 ATOM 
                 125 
                 CB 
                 THR 
                 A 
                 15 
                 83.560 
                 31.430 
                 20.208 
                 1.00 
                 82.34 
                 C 
               
               
                 ATOM 
                 126 
                 OG1 
                 THR 
                 A 
                 15 
                 83.185 
                 32.715 
                 20.719 
                 1.00 
                 83.75 
                 O 
               
               
                 ATOM 
                 127 
                 CG2 
                 THR 
                 A 
                 15 
                 84.461 
                 30.721 
                 21.209 
                 1.00 
                 80.67 
                 C 
               
               
                 ATOM 
                 128 
                 C 
                 THR 
                 A 
                 15 
                 83.385 
                 32.364 
                 17.880 
                 1.00 
                 86.18 
                 C 
               
               
                 ATOM 
                 129 
                 O 
                 THR 
                 A 
                 15 
                 83.780 
                 33.402 
                 17.344 
                 1.00 
                 86.80 
                 O 
               
               
                 ATOM 
                 130 
                 N 
                 GLU 
                 A 
                 16 
                 82.185 
                 31.839 
                 17.656 
                 1.00 
                 90.27 
                 N 
               
               
                 ATOM 
                 131 
                 CA 
                 GLU 
                 A 
                 16 
                 81.237 
                 32.423 
                 16.714 
                 1.00 
                 95.92 
                 C 
               
               
                 ATOM 
                 132 
                 CB 
                 GLU 
                 A 
                 16 
                 79.978 
                 31.557 
                 16.663 
                 1.00 
                 99.78 
                 C 
               
               
                 ATOM 
                 133 
                 CG 
                 GLU 
                 A 
                 16 
                 78.944 
                 31.990 
                 15.636 
                 1.00 
                 101.53 
                 C 
               
               
                 ATOM 
                 134 
                 CD 
                 GLU 
                 A 
                 16 
                 77.828 
                 30.973 
                 15.465 
                 1.00 
                 104.50 
                 C 
               
               
                 ATOM 
                 135 
                 OE1 
                 GLU 
                 A 
                 16 
                 78.104 
                 29.755 
                 15.519 
                 1.00 
                 106.60 
                 O 
               
               
                 ATOM 
                 136 
                 OE2 
                 GLU 
                 A 
                 16 
                 76.670 
                 31.390 
                 15.262 
                 1.00 
                 104.82 
                 O 
               
               
                 ATOM 
                 137 
                 C 
                 GLU 
                 A 
                 16 
                 80.870 
                 33.868 
                 17.052 
                 1.00 
                 98.70 
                 C 
               
               
                 ATOM 
                 138 
                 O 
                 GLU 
                 A 
                 16 
                 80.799 
                 34.715 
                 16.159 
                 1.00 
                 100.81 
                 O 
               
               
                 ATOM 
                 139 
                 N 
                 GLN 
                 A 
                 17 
                 80.660 
                 34.144 
                 18.337 
                 1.00 
                 101.15 
                 N 
               
               
                 ATOM 
                 140 
                 CA 
                 GLN 
                 A 
                 17 
                 80.240 
                 35.477 
                 18.794 
                 1.00 
                 101.61 
                 C 
               
               
                 ATOM 
                 141 
                 CB 
                 GLN 
                 A 
                 17 
                 79.328 
                 35.375 
                 20.035 
                 1.00 
                 106.37 
                 C 
               
               
                 ATOM 
                 142 
                 CG 
                 GLN 
                 A 
                 17 
                 79.957 
                 34.784 
                 21.301 
                 1.00 
                 110.91 
                 C 
               
               
                 ATOM 
                 143 
                 CD 
                 GLN 
                 A 
                 17 
                 79.913 
                 33.260 
                 21.369 
                 1.00 
                 112.06 
                 C 
               
               
                 ATOM 
                 144 
                 OE1 
                 GLN 
                 A 
                 17 
                 79.731 
                 32.579 
                 20.358 
                 1.00 
                 112.42 
                 O 
               
               
                 ATOM 
                 145 
                 NE2 
                 GLN 
                 A 
                 17 
                 80.090 
                 32.721 
                 22.571 
                 1.00 
                 111.28 
                 N 
               
               
                 ATOM 
                 146 
                 C 
                 GLN 
                 A 
                 17 
                 81.395 
                 36.460 
                 19.063 
                 1.00 
                 95.82 
                 C 
               
               
                 ATOM 
                 147 
                 O 
                 GLN 
                 A 
                 17 
                 81.150 
                 37.635 
                 19.333 
                 1.00 
                 91.71 
                 O 
               
               
                 ATOM 
                 148 
                 N 
                 THR 
                 A 
                 18 
                 82.639 
                 35.990 
                 18.977 
                 1.00 
                 93.69 
                 N 
               
               
                 ATOM 
                 149 
                 CA 
                 THR 
                 A 
                 18 
                 83.815 
                 36.837 
                 19.228 
                 1.00 
                 91.59 
                 C 
               
               
                 ATOM 
                 150 
                 CB 
                 THR 
                 A 
                 18 
                 85.127 
                 36.039 
                 19.082 
                 1.00 
                 89.62 
                 C 
               
               
                 ATOM 
                 151 
                 OG1 
                 THR 
                 A 
                 18 
                 85.113 
                 34.926 
                 19.982 
                 1.00 
                 91.84 
                 O 
               
               
                 ATOM 
                 152 
                 CG2 
                 THR 
                 A 
                 18 
                 86.335 
                 36.912 
                 19.388 
                 1.00 
                 88.68 
                 C 
               
               
                 ATOM 
                 153 
                 C 
                 THR 
                 A 
                 18 
                 83.873 
                 38.056 
                 18.303 
                 1.00 
                 91.59 
                 C 
               
               
                 ATOM 
                 154 
                 O 
                 THR 
                 A 
                 18 
                 84.147 
                 39.165 
                 18.756 
                 1.00 
                 93.09 
                 O 
               
               
                 ATOM 
                 155 
                 N 
                 PHE 
                 A 
                 19 
                 83.631 
                 37.838 
                 17.013 
                 1.00 
                 92.07 
                 N 
               
               
                 ATOM 
                 156 
                 CA 
                 PHE 
                 A 
                 19 
                 83.607 
                 38.916 
                 16.022 
                 1.00 
                 91.00 
                 C 
               
               
                 ATOM 
                 157 
                 CB 
                 PHE 
                 A 
                 19 
                 84.372 
                 38.500 
                 14.758 
                 1.00 
                 89.62 
                 C 
               
               
                 ATOM 
                 158 
                 CG 
                 PHE 
                 A 
                 19 
                 85.861 
                 38.393 
                 14.941 
                 1.00 
                 86.57 
                 C 
               
               
                 ATOM 
                 159 
                 CD1 
                 PHE 
                 A 
                 19 
                 86.713 
                 39.338 
                 14.388 
                 1.00 
                 84.95 
                 C 
               
               
                 ATOM 
                 160 
                 CE1 
                 PHE 
                 A 
                 19 
                 88.085 
                 39.234 
                 14.543 
                 1.00 
                 84.49 
                 C 
               
               
                 ATOM 
                 161 
                 CZ 
                 PHE 
                 A 
                 19 
                 88.621 
                 38.176 
                 15.253 
                 1.00 
                 84.63 
                 C 
               
               
                 ATOM 
                 162 
                 CE2 
                 PHE 
                 A 
                 19 
                 87.785 
                 37.223 
                 15.802 
                 1.00 
                 85.95 
                 C 
               
               
                 ATOM 
                 163 
                 CD2 
                 PHE 
                 A 
                 19 
                 86.413 
                 37.332 
                 15.643 
                 1.00 
                 86.68 
                 C 
               
               
                 ATOM 
                 164 
                 C 
                 PHE 
                 A 
                 19 
                 82.154 
                 39.213 
                 15.652 
                 1.00 
                 91.80 
                 C 
               
               
                 ATOM 
                 165 
                 O 
                 PHE 
                 A 
                 19 
                 81.265 
                 38.417 
                 15.966 
                 1.00 
                 92.30 
                 O 
               
               
                 ATOM 
                 166 
                 N 
                 PRO 
                 A 
                 20 
                 81.900 
                 40.359 
                 14.985 
                 1.00 
                 92.36 
                 N 
               
               
                 ATOM 
                 167 
                 CA 
                 PRO 
                 A 
                 20 
                 80.544 
                 40.650 
                 14.497 
                 1.00 
                 93.18 
                 C 
               
               
                 ATOM 
                 168 
                 CB 
                 PRO 
                 A 
                 20 
                 80.708 
                 41.983 
                 13.761 
                 1.00 
                 93.72 
                 C 
               
               
                 ATOM 
                 169 
                 CG 
                 PRO 
                 A 
                 20 
                 81.914 
                 42.610 
                 14.364 
                 1.00 
                 93.17 
                 C 
               
               
                 ATOM 
                 170 
                 CD 
                 PRO 
                 A 
                 20 
                 82.827 
                 41.476 
                 14.724 
                 1.00 
                 92.10 
                 C 
               
               
                 ATOM 
                 171 
                 C 
                 PRO 
                 A 
                 20 
                 80.048 
                 39.579 
                 13.529 
                 1.00 
                 92.47 
                 C 
               
               
                 ATOM 
                 172 
                 O 
                 PRO 
                 A 
                 20 
                 78.861 
                 39.253 
                 13.516 
                 1.00 
                 94.83 
                 O 
               
               
                 ATOM 
                 173 
                 N 
                 TYR 
                 A 
                 21 
                 80.973 
                 39.050 
                 12.731 
                 1.00 
                 89.94 
                 N 
               
               
                 ATOM 
                 174 
                 CA 
                 TYR 
                 A 
                 21 
                 80.694 
                 37.973 
                 11.791 
                 1.00 
                 87.48 
                 C 
               
               
                 ATOM 
                 175 
                 CB 
                 TYR 
                 A 
                 21 
                 81.251 
                 38.310 
                 10.402 
                 1.00 
                 86.87 
                 C 
               
               
                 ATOM 
                 176 
                 CG 
                 TYR 
                 A 
                 21 
                 82.767 
                 38.336 
                 10.269 
                 1.00 
                 85.77 
                 C 
               
               
                 ATOM 
                 177 
                 CD1 
                 TYR 
                 A 
                 21 
                 83.520 
                 39.408 
                 10.744 
                 1.00 
                 85.72 
                 C 
               
               
                 ATOM 
                 178 
                 CE1 
                 TYR 
                 A 
                 21 
                 84.900 
                 39.438 
                 10.599 
                 1.00 
                 86.03 
                 C 
               
               
                 ATOM 
                 179 
                 CZ 
                 TYR 
                 A 
                 21 
                 85.545 
                 38.393 
                 9.961 
                 1.00 
                 85.88 
                 C 
               
               
                 ATOM 
                 180 
                 OH 
                 TYR 
                 A 
                 21 
                 86.915 
                 38.409 
                 9.808 
                 1.00 
                 85.79 
                 O 
               
               
                 ATOM 
                 181 
                 CE2 
                 TYR 
                 A 
                 21 
                 84.817 
                 37.327 
                 9.472 
                 1.00 
                 86.31 
                 C 
               
               
                 ATOM 
                 182 
                 CD2 
                 TYR 
                 A 
                 21 
                 83.440 
                 37.305 
                 9.622 
                 1.00 
                 85.97 
                 C 
               
               
                 ATOM 
                 183 
                 C 
                 TYR 
                 A 
                 21 
                 81.291 
                 36.676 
                 12.326 
                 1.00 
                 85.29 
                 C 
               
               
                 ATOM 
                 184 
                 O 
                 TYR 
                 A 
                 21 
                 82.034 
                 36.690 
                 13.307 
                 1.00 
                 85.15 
                 O 
               
               
                 ATOM 
                 185 
                 N 
                 ASP 
                 A 
                 22 
                 80.952 
                 35.556 
                 11.695 
                 1.00 
                 84.23 
                 N 
               
               
                 ATOM 
                 186 
                 CA 
                 ASP 
                 A 
                 22 
                 81.479 
                 34.259 
                 12.112 
                 1.00 
                 81.39 
                 C 
               
               
                 ATOM 
                 187 
                 CB 
                 ASP 
                 A 
                 22 
                 80.601 
                 33.118 
                 11.595 
                 1.00 
                 79.88 
                 C 
               
               
                 ATOM 
                 188 
                 CG 
                 ASP 
                 A 
                 22 
                 80.934 
                 31.781 
                 12.235 
                 1.00 
                 80.48 
                 C 
               
               
                 ATOM 
                 189 
                 OD1 
                 ASP 
                 A 
                 22 
                 81.957 
                 31.686 
                 12.950 
                 1.00 
                 80.95 
                 O 
               
               
                 ATOM 
                 190 
                 OD2 
                 ASP 
                 A 
                 22 
                 80.167 
                 30.817 
                 12.025 
                 1.00 
                 77.89 
                 O 
               
               
                 ATOM 
                 191 
                 C 
                 ASP 
                 A 
                 22 
                 82.899 
                 34.119 
                 11.584 
                 1.00 
                 80.14 
                 C 
               
               
                 ATOM 
                 192 
                 O 
                 ASP 
                 A 
                 22 
                 83.105 
                 33.974 
                 10.377 
                 1.00 
                 83.56 
                 O 
               
               
                 ATOM 
                 193 
                 N 
                 ASN 
                 A 
                 23 
                 83.871 
                 34.176 
                 12.490 
                 1.00 
                 78.77 
                 N 
               
               
                 ATOM 
                 194 
                 CA 
                 ASN 
                 A 
                 23 
                 85.278 
                 34.094 
                 12.118 
                 1.00 
                 78.72 
                 C 
               
               
                 ATOM 
                 195 
                 CB 
                 ASN 
                 A 
                 23 
                 85.956 
                 35.449 
                 12.324 
                 1.00 
                 79.93 
                 C 
               
               
                 ATOM 
                 196 
                 CG 
                 ASN 
                 A 
                 23 
                 87.323 
                 35.515 
                 11.656 
                 1.00 
                 82.32 
                 C 
               
               
                 ATOM 
                 197 
                 OD1 
                 ASN 
                 A 
                 23 
                 88.345 
                 35.469 
                 12.332 
                 1.00 
                 87.78 
                 O 
               
               
                 ATOM 
                 198 
                 ND2 
                 ASN 
                 A 
                 23 
                 87.349 
                 35.564 
                 10.327 
                 1.00 
                 82.73 
                 N 
               
               
                 ATOM 
                 199 
                 C 
                 ASN 
                 A 
                 23 
                 86.021 
                 33.010 
                 12.901 
                 1.00 
                 77.85 
                 C 
               
               
                 ATOM 
                 200 
                 O 
                 ASN 
                 A 
                 23 
                 87.188 
                 33.174 
                 13.256 
                 1.00 
                 76.33 
                 O 
               
               
                 ATOM 
                 201 
                 N 
                 ARG 
                 A 
                 24 
                 85.346 
                 31.896 
                 13.167 
                 1.00 
                 77.43 
                 N 
               
               
                 ATOM 
                 202 
                 CA 
                 ARG 
                 A 
                 24 
                 85.985 
                 30.779 
                 13.851 
                 1.00 
                 78.84 
                 C 
               
               
                 ATOM 
                 203 
                 CB 
                 ARG 
                 A 
                 24 
                 84.961 
                 29.708 
                 14.215 
                 1.00 
                 82.46 
                 C 
               
               
                 ATOM 
                 204 
                 CG 
                 ARG 
                 A 
                 24 
                 83.948 
                 30.142 
                 15.261 
                 1.00 
                 87.00 
                 C 
               
               
                 ATOM 
                 205 
                 CD 
                 ARG 
                 A 
                 24 
                 82.841 
                 29.113 
                 15.404 
                 1.00 
                 90.70 
                 C 
               
               
                 ATOM 
                 206 
                 NE 
                 ARG 
                 A 
                 24 
                 81.997 
                 29.063 
                 14.213 
                 1.00 
                 94.41 
                 N 
               
               
                 ATOM 
                 207 
                 CZ 
                 ARG 
                 A 
                 24 
                 81.062 
                 28.146 
                 13.978 
                 1.00 
                 100.00 
                 C 
               
               
                 ATOM 
                 208 
                 NH1 
                 ARG 
                 A 
                 24 
                 80.832 
                 27.168 
                 14.850 
                 1.00 
                 102.61 
                 N 
               
               
                 ATOM 
                 209 
                 NH2 
                 ARG 
                 A 
                 24 
                 80.355 
                 28.203 
                 12.855 
                 1.00 
                 102.93 
                 N 
               
               
                 ATOM 
                 210 
                 C 
                 ARG 
                 A 
                 24 
                 87.049 
                 30.181 
                 12.936 
                 1.00 
                 77.88 
                 C 
               
               
                 ATOM 
                 211 
                 O 
                 ARG 
                 A 
                 24 
                 86.931 
                 30.270 
                 11.715 
                 1.00 
                 79.51 
                 O 
               
               
                 ATOM 
                 212 
                 N 
                 PRO 
                 A 
                 25 
                 88.092 
                 29.562 
                 13.517 
                 1.00 
                 76.89 
                 N 
               
               
                 ATOM 
                 213 
                 CA 
                 PRO 
                 A 
                 25 
                 89.160 
                 28.944 
                 12.722 
                 1.00 
                 76.11 
                 C 
               
               
                 ATOM 
                 214 
                 CB 
                 PRO 
                 A 
                 25 
                 89.920 
                 28.115 
                 13.758 
                 1.00 
                 75.95 
                 C 
               
               
                 ATOM 
                 215 
                 CG 
                 PRO 
                 A 
                 25 
                 89.723 
                 28.849 
                 15.034 
                 1.00 
                 75.64 
                 C 
               
               
                 ATOM 
                 216 
                 CD 
                 PRO 
                 A 
                 25 
                 88.354 
                 29.457 
                 14.964 
                 1.00 
                 75.85 
                 C 
               
               
                 ATOM 
                 217 
                 C 
                 PRO 
                 A 
                 25 
                 88.683 
                 28.040 
                 11.575 
                 1.00 
                 76.14 
                 C 
               
               
                 ATOM 
                 218 
                 O 
                 PRO 
                 A 
                 25 
                 89.365 
                 27.944 
                 10.553 
                 1.00 
                 78.16 
                 O 
               
               
                 ATOM 
                 219 
                 N 
                 VAL 
                 A 
                 26 
                 87.534 
                 27.386 
                 11.750 
                 1.00 
                 74.03 
                 N 
               
               
                 ATOM 
                 220 
                 CA 
                 VAL 
                 A 
                 26 
                 87.001 
                 26.463 
                 10.742 
                 1.00 
                 74.16 
                 C 
               
               
                 ATOM 
                 221 
                 CB 
                 VAL 
                 A 
                 26 
                 86.097 
                 25.379 
                 11.375 
                 1.00 
                 75.02 
                 C 
               
               
                 ATOM 
                 222 
                 CG1 
                 VAL 
                 A 
                 26 
                 86.876 
                 24.575 
                 12.405 
                 1.00 
                 76.87 
                 C 
               
               
                 ATOM 
                 223 
                 CG2 
                 VAL 
                 A 
                 26 
                 84.841 
                 25.980 
                 11.996 
                 1.00 
                 75.97 
                 C 
               
               
                 ATOM 
                 224 
                 C 
                 VAL 
                 A 
                 26 
                 86.235 
                 27.141 
                 9.608 
                 1.00 
                 76.22 
                 C 
               
               
                 ATOM 
                 225 
                 O 
                 VAL 
                 A 
                 26 
                 85.985 
                 26.517 
                 8.578 
                 1.00 
                 80.23 
                 O 
               
               
                 ATOM 
                 226 
                 N 
                 VAL 
                 A 
                 27 
                 85.862 
                 28.405 
                 9.788 
                 1.00 
                 77.19 
                 N 
               
               
                 ATOM 
                 227 
                 CA 
                 VAL 
                 A 
                 27 
                 85.106 
                 29.132 
                 8.766 
                 1.00 
                 77.16 
                 C 
               
               
                 ATOM 
                 228 
                 CB 
                 VAL 
                 A 
                 27 
                 84.644 
                 30.512 
                 9.286 
                 1.00 
                 78.69 
                 C 
               
               
                 ATOM 
                 229 
                 CG1 
                 VAL 
                 A 
                 27 
                 84.097 
                 31.382 
                 8.159 
                 1.00 
                 81.69 
                 C 
               
               
                 ATOM 
                 230 
                 CG2 
                 VAL 
                 A 
                 27 
                 83.600 
                 30.338 
                 10.378 
                 1.00 
                 78.01 
                 C 
               
               
                 ATOM 
                 231 
                 C 
                 VAL 
                 A 
                 27 
                 85.940 
                 29.305 
                 7.493 
                 1.00 
                 75.90 
                 C 
               
               
                 ATOM 
                 232 
                 O 
                 VAL 
                 A 
                 27 
                 87.110 
                 29.679 
                 7.569 
                 1.00 
                 76.15 
                 O 
               
               
                 ATOM 
                 233 
                 N 
                 PRO 
                 A 
                 28 
                 85.340 
                 29.026 
                 6.321 
                 1.00 
                 76.46 
                 N 
               
               
                 ATOM 
                 234 
                 CA 
                 PRO 
                 A 
                 28 
                 86.056 
                 29.172 
                 5.053 
                 1.00 
                 77.60 
                 C 
               
               
                 ATOM 
                 235 
                 CB 
                 PRO 
                 A 
                 28 
                 85.147 
                 28.453 
                 4.056 
                 1.00 
                 76.68 
                 C 
               
               
                 ATOM 
                 236 
                 CG 
                 PRO 
                 A 
                 28 
                 83.790 
                 28.562 
                 4.637 
                 1.00 
                 77.52 
                 C 
               
               
                 ATOM 
                 237 
                 CD 
                 PRO 
                 A 
                 28 
                 83.994 
                 28.461 
                 6.119 
                 1.00 
                 78.17 
                 C 
               
               
                 ATOM 
                 238 
                 C 
                 PRO 
                 A 
                 28 
                 86.248 
                 30.626 
                 4.631 
                 1.00 
                 78.58 
                 C 
               
               
                 ATOM 
                 239 
                 O 
                 PRO 
                 A 
                 28 
                 85.462 
                 31.496 
                 5.015 
                 1.00 
                 81.59 
                 O 
               
               
                 ATOM 
                 240 
                 N 
                 LEU 
                 A 
                 29 
                 87.292 
                 30.865 
                 3.841 
                 1.00 
                 77.97 
                 N 
               
               
                 ATOM 
                 241 
                 CA 
                 LEU 
                 A 
                 29 
                 87.631 
                 32.196 
                 3.347 
                 1.00 
                 79.27 
                 C 
               
               
                 ATOM 
                 242 
                 CB 
                 LEU 
                 A 
                 29 
                 89.133 
                 32.447 
                 3.503 
                 1.00 
                 77.54 
                 C 
               
               
                 ATOM 
                 243 
                 CG 
                 LEU 
                 A 
                 29 
                 89.675 
                 32.775 
                 4.904 
                 1.00 
                 76.54 
                 C 
               
               
                 ATOM 
                 244 
                 CD1 
                 LEU 
                 A 
                 29 
                 91.176 
                 32.541 
                 4.937 
                 1.00 
                 75.32 
                 C 
               
               
                 ATOM 
                 245 
                 CD2 
                 LEU 
                 A 
                 29 
                 89.013 
                 31.971 
                 6.011 
                 1.00 
                 76.40 
                 C 
               
               
                 ATOM 
                 246 
                 C 
                 LEU 
                 A 
                 29 
                 87.228 
                 32.296 
                 1.880 
                 1.00 
                 82.98 
                 C 
               
               
                 ATOM 
                 247 
                 O 
                 LEU 
                 A 
                 29 
                 87.705 
                 31.521 
                 1.050 
                 1.00 
                 85.82 
                 O 
               
               
                 ATOM 
                 248 
                 N 
                 GLN 
                 A 
                 30 
                 86.360 
                 33.256 
                 1.563 
                 1.00 
                 85.08 
                 N 
               
               
                 ATOM 
                 249 
                 CA 
                 GLN 
                 A 
                 30 
                 85.833 
                 33.409 
                 0.207 
                 1.00 
                 84.07 
                 C 
               
               
                 ATOM 
                 250 
                 CB 
                 GLN 
                 A 
                 30 
                 84.644 
                 32.461 
                 0.010 
                 1.00 
                 83.65 
                 C 
               
               
                 ATOM 
                 251 
                 CG 
                 GLN 
                 A 
                 30 
                 83.505 
                 32.673 
                 1.004 
                 1.00 
                 85.40 
                 C 
               
               
                 ATOM 
                 252 
                 CD 
                 GLN 
                 A 
                 30 
                 82.633 
                 31.442 
                 1.217 
                 1.00 
                 85.90 
                 C 
               
               
                 ATOM 
                 253 
                 OE1 
                 GLN 
                 A 
                 30 
                 83.118 
                 30.311 
                 1.215 
                 1.00 
                 83.42 
                 O 
               
               
                 ATOM 
                 254 
                 NE2 
                 GLN 
                 A 
                 30 
                 81.341 
                 31.665 
                 1.432 
                 1.00 
                 86.12 
                 N 
               
               
                 ATOM 
                 255 
                 C 
                 GLN 
                 A 
                 30 
                 85.427 
                 34.856 
                 −0.081 
                 1.00 
                 85.69 
                 C 
               
               
                 ATOM 
                 256 
                 O 
                 GLN 
                 A 
                 30 
                 84.653 
                 35.455 
                 0.666 
                 1.00 
                 86.01 
                 O 
               
               
                 ATOM 
                 257 
                 N 
                 TYR 
                 A 
                 31 
                 85.965 
                 35.405 
                 −1.167 
                 1.00 
                 89.33 
                 N 
               
               
                 ATOM 
                 258 
                 CA 
                 TYR 
                 A 
                 31 
                 85.709 
                 36.788 
                 −1.591 
                 1.00 
                 91.39 
                 C 
               
               
                 ATOM 
                 259 
                 CB 
                 TYR 
                 A 
                 31 
                 84.343 
                 36.903 
                 −2.281 
                 1.00 
                 91.41 
                 C 
               
               
                 ATOM 
                 260 
                 CG 
                 TYR 
                 A 
                 31 
                 84.183 
                 38.164 
                 −3.108 
                 1.00 
                 92.21 
                 C 
               
               
                 ATOM 
                 261 
                 CD1 
                 TYR 
                 A 
                 31 
                 85.077 
                 38.463 
                 −4.132 
                 1.00 
                 93.65 
                 C 
               
               
                 ATOM 
                 262 
                 CE1 
                 TYR 
                 A 
                 31 
                 84.937 
                 39.607 
                 −4.898 
                 1.00 
                 94.01 
                 C 
               
               
                 ATOM 
                 263 
                 CZ 
                 TYR 
                 A 
                 31 
                 83.888 
                 40.466 
                 −4.653 
                 1.00 
                 94.14 
                 C 
               
               
                 ATOM 
                 264 
                 OH 
                 TYR 
                 A 
                 31 
                 83.753 
                 41.599 
                 −5.418 
                 1.00 
                 94.67 
                 O 
               
               
                 ATOM 
                 265 
                 CE2 
                 TYR 
                 A 
                 31 
                 82.982 
                 40.191 
                 −3.647 
                 1.00 
                 94.39 
                 C 
               
               
                 ATOM 
                 266 
                 CD2 
                 TYR 
                 A 
                 31 
                 83.131 
                 39.043 
                 −2.884 
                 1.00 
                 93.28 
                 C 
               
               
                 ATOM 
                 267 
                 C 
                 TYR 
                 A 
                 31 
                 85.835 
                 37.782 
                 −0.434 
                 1.00 
                 89.84 
                 C 
               
               
                 ATOM 
                 268 
                 O 
                 TYR 
                 A 
                 31 
                 84.935 
                 38.585 
                 −0.175 
                 1.00 
                 91.00 
                 O 
               
               
                 ATOM 
                 269 
                 N 
                 MET 
                 A 
                 32 
                 86.975 
                 37.710 
                 0.248 
                 1.00 
                 87.23 
                 N 
               
               
                 ATOM 
                 270 
                 CA 
                 MET 
                 A 
                 32 
                 87.272 
                 38.560 
                 1.394 
                 1.00 
                 84.81 
                 C 
               
               
                 ATOM 
                 271 
                 CB 
                 MET 
                 A 
                 32 
                 87.742 
                 37.702 
                 2.566 
                 1.00 
                 83.80 
                 C 
               
               
                 ATOM 
                 272 
                 CG 
                 MET 
                 A 
                 32 
                 86.653 
                 36.922 
                 3.268 
                 1.00 
                 84.29 
                 C 
               
               
                 ATOM 
                 273 
                 SD 
                 MET 
                 A 
                 32 
                 87.372 
                 35.892 
                 4.557 
                 1.00 
                 88.43 
                 S 
               
               
                 ATOM 
                 274 
                 CE 
                 MET 
                 A 
                 32 
                 85.911 
                 35.425 
                 5.482 
                 1.00 
                 88.00 
                 C 
               
               
                 ATOM 
                 275 
                 C 
                 MET 
                 A 
                 32 
                 88.370 
                 39.561 
                 1.072 
                 1.00 
                 83.30 
                 C 
               
               
                 ATOM 
                 276 
                 O 
                 MET 
                 A 
                 32 
                 89.194 
                 39.332 
                 0.187 
                 1.00 
                 82.99 
                 O 
               
               
                 ATOM 
                 277 
                 N 
                 THR 
                 A 
                 33 
                 88.379 
                 40.665 
                 1.812 
                 1.00 
                 84.00 
                 N 
               
               
                 ATOM 
                 278 
                 CA 
                 THR 
                 A 
                 33 
                 89.443 
                 41.655 
                 1.708 
                 1.00 
                 85.10 
                 C 
               
               
                 ATOM 
                 279 
                 CB 
                 THR 
                 A 
                 33 
                 89.066 
                 42.968 
                 2.408 
                 1.00 
                 86.62 
                 C 
               
               
                 ATOM 
                 280 
                 OG1 
                 THR 
                 A 
                 33 
                 88.682 
                 42.694 
                 3.761 
                 1.00 
                 85.39 
                 O 
               
               
                 ATOM 
                 281 
                 CG2 
                 THR 
                 A 
                 33 
                 87.911 
                 43.640 
                 1.687 
                 1.00 
                 88.78 
                 C 
               
               
                 ATOM 
                 282 
                 C 
                 THR 
                 A 
                 33 
                 90.679 
                 41.072 
                 2.374 
                 1.00 
                 84.97 
                 C 
               
               
                 ATOM 
                 283 
                 O 
                 THR 
                 A 
                 33 
                 90.570 
                 40.134 
                 3.167 
                 1.00 
                 84.64 
                 O 
               
               
                 ATOM 
                 284 
                 N 
                 PHE 
                 A 
                 34 
                 91.847 
                 41.626 
                 2.068 
                 1.00 
                 84.71 
                 N 
               
               
                 ATOM 
                 285 
                 CA 
                 PHE 
                 A 
                 34 
                 93.096 
                 41.070 
                 2.584 
                 1.00 
                 84.09 
                 C 
               
               
                 ATOM 
                 286 
                 CB 
                 PHE 
                 A 
                 34 
                 94.300 
                 41.925 
                 2.201 
                 1.00 
                 82.95 
                 C 
               
               
                 ATOM 
                 287 
                 CG 
                 PHE 
                 A 
                 34 
                 95.605 
                 41.323 
                 2.623 
                 1.00 
                 81.81 
                 C 
               
               
                 ATOM 
                 288 
                 CD1 
                 PHE 
                 A 
                 34 
                 96.087 
                 40.193 
                 1.984 
                 1.00 
                 81.66 
                 C 
               
               
                 ATOM 
                 289 
                 CE1 
                 PHE 
                 A 
                 34 
                 97.283 
                 39.618 
                 2.369 
                 1.00 
                 81.94 
                 C 
               
               
                 ATOM 
                 290 
                 CZ 
                 PHE 
                 A 
                 34 
                 98.014 
                 40.170 
                 3.406 
                 1.00 
                 80.79 
                 C 
               
               
                 ATOM 
                 291 
                 CE2 
                 PHE 
                 A 
                 34 
                 97.540 
                 41.294 
                 4.057 
                 1.00 
                 81.75 
                 C 
               
               
                 ATOM 
                 292 
                 CD2 
                 PHE 
                 A 
                 34 
                 96.339 
                 41.863 
                 3.668 
                 1.00 
                 82.13 
                 C 
               
               
                 ATOM 
                 293 
                 C 
                 PHE 
                 A 
                 34 
                 93.078 
                 40.861 
                 4.094 
                 1.00 
                 85.55 
                 C 
               
               
                 ATOM 
                 294 
                 O 
                 PHE 
                 A 
                 34 
                 93.405 
                 39.779 
                 4.571 
                 1.00 
                 83.63 
                 O 
               
               
                 ATOM 
                 295 
                 N 
                 GLN 
                 A 
                 35 
                 92.682 
                 41.892 
                 4.835 
                 1.00 
                 89.59 
                 N 
               
               
                 ATOM 
                 296 
                 CA 
                 GLN 
                 A 
                 35 
                 92.652 
                 41.828 
                 6.298 
                 1.00 
                 92.31 
                 C 
               
               
                 ATOM 
                 297 
                 CB 
                 GLN 
                 A 
                 35 
                 92.176 
                 43.159 
                 6.884 
                 1.00 
                 97.58 
                 C 
               
               
                 ATOM 
                 298 
                 CG 
                 GLN 
                 A 
                 35 
                 92.242 
                 43.228 
                 8.401 
                 1.00 
                 100.31 
                 C 
               
               
                 ATOM 
                 299 
                 CD 
                 GLN 
                 A 
                 35 
                 91.806 
                 44.578 
                 8.923 
                 1.00 
                 104.73 
                 C 
               
               
                 ATOM 
                 300 
                 OE1 
                 GLN 
                 A 
                 35 
                 90.700 
                 45.025 
                 8.633 
                 1.00 
                 108.24 
                 O 
               
               
                 ATOM 
                 301 
                 NE2 
                 GLN 
                 A 
                 35 
                 92.663 
                 45.233 
                 9.703 
                 1.00 
                 108.47 
                 N 
               
               
                 ATOM 
                 302 
                 C 
                 GLN 
                 A 
                 35 
                 91.768 
                 40.698 
                 6.819 
                 1.00 
                 87.97 
                 C 
               
               
                 ATOM 
                 303 
                 O 
                 GLN 
                 A 
                 35 
                 92.081 
                 40.082 
                 7.840 
                 1.00 
                 88.49 
                 O 
               
               
                 ATOM 
                 304 
                 N 
                 GLU 
                 A 
                 36 
                 90.672 
                 40.432 
                 6.115 
                 1.00 
                 83.87 
                 N 
               
               
                 ATOM 
                 305 
                 CA 
                 GLU 
                 A 
                 36 
                 89.734 
                 39.383 
                 6.508 
                 1.00 
                 81.96 
                 C 
               
               
                 ATOM 
                 306 
                 CB 
                 GLU 
                 A 
                 36 
                 88.388 
                 39.590 
                 5.809 
                 1.00 
                 82.61 
                 C 
               
               
                 ATOM 
                 307 
                 CG 
                 GLU 
                 A 
                 36 
                 87.670 
                 40.854 
                 6.258 
                 1.00 
                 84.88 
                 C 
               
               
                 ATOM 
                 308 
                 CD 
                 GLU 
                 A 
                 36 
                 86.424 
                 41.172 
                 5.449 
                 1.00 
                 85.92 
                 C 
               
               
                 ATOM 
                 309 
                 OE1 
                 GLU 
                 A 
                 36 
                 86.237 
                 40.599 
                 4.356 
                 1.00 
                 88.20 
                 O 
               
               
                 ATOM 
                 310 
                 OE2 
                 GLU 
                 A 
                 36 
                 85.633 
                 42.019 
                 5.908 
                 1.00 
                 87.08 
                 O 
               
               
                 ATOM 
                 311 
                 C 
                 GLU 
                 A 
                 36 
                 90.264 
                 37.969 
                 6.244 
                 1.00 
                 78.74 
                 C 
               
               
                 ATOM 
                 312 
                 O 
                 GLU 
                 A 
                 36 
                 90.151 
                 37.099 
                 7.110 
                 1.00 
                 79.13 
                 O 
               
               
                 ATOM 
                 313 
                 N 
                 TRP 
                 A 
                 37 
                 90.850 
                 37.739 
                 5.068 
                 1.00 
                 74.66 
                 N 
               
               
                 ATOM 
                 314 
                 CA 
                 TRP 
                 A 
                 37 
                 91.333 
                 36.397 
                 4.715 
                 1.00 
                 71.51 
                 C 
               
               
                 ATOM 
                 315 
                 CB 
                 TRP 
                 A 
                 37 
                 91.230 
                 36.128 
                 3.192 
                 1.00 
                 70.80 
                 C 
               
               
                 ATOM 
                 316 
                 CG 
                 TRP 
                 A 
                 37 
                 92.341 
                 36.670 
                 2.332 
                 1.00 
                 67.87 
                 C 
               
               
                 ATOM 
                 317 
                 CD1 
                 TRP 
                 A 
                 37 
                 92.305 
                 37.789 
                 1.559 
                 1.00 
                 68.80 
                 C 
               
               
                 ATOM 
                 318 
                 NE1 
                 TRP 
                 A 
                 37 
                 93.506 
                 37.958 
                 0.912 
                 1.00 
                 69.34 
                 N 
               
               
                 ATOM 
                 319 
                 CE2 
                 TRP 
                 A 
                 37 
                 94.342 
                 36.932 
                 1.257 
                 1.00 
                 66.64 
                 C 
               
               
                 ATOM 
                 320 
                 CD2 
                 TRP 
                 A 
                 37 
                 93.638 
                 36.096 
                 2.143 
                 1.00 
                 65.97 
                 C 
               
               
                 ATOM 
                 321 
                 CE3 
                 TRP 
                 A 
                 37 
                 94.277 
                 34.962 
                 2.649 
                 1.00 
                 67.44 
                 C 
               
               
                 ATOM 
                 322 
                 CZ3 
                 TRP 
                 A 
                 37 
                 95.578 
                 34.702 
                 2.256 
                 1.00 
                 68.15 
                 C 
               
               
                 ATOM 
                 323 
                 CH2 
                 TRP 
                 A 
                 37 
                 96.251 
                 35.555 
                 1.371 
                 1.00 
                 68.14 
                 C 
               
               
                 ATOM 
                 324 
                 CZ2 
                 TRP 
                 A 
                 37 
                 95.650 
                 36.671 
                 0.862 
                 1.00 
                 67.60 
                 C 
               
               
                 ATOM 
                 325 
                 C 
                 TRP 
                 A 
                 37 
                 92.741 
                 36.106 
                 5.246 
                 1.00 
                 69.80 
                 C 
               
               
                 ATOM 
                 326 
                 O 
                 TRP 
                 A 
                 37 
                 93.022 
                 34.984 
                 5.657 
                 1.00 
                 68.47 
                 O 
               
               
                 ATOM 
                 327 
                 N 
                 TRP 
                 A 
                 38 
                 93.619 
                 37.105 
                 5.240 
                 1.00 
                 72.07 
                 N 
               
               
                 ATOM 
                 328 
                 CA 
                 TRP 
                 A 
                 38 
                 95.006 
                 36.918 
                 5.697 
                 1.00 
                 75.67 
                 C 
               
               
                 ATOM 
                 329 
                 CB 
                 TRP 
                 A 
                 38 
                 95.836 
                 38.173 
                 5.417 
                 1.00 
                 77.42 
                 C 
               
               
                 ATOM 
                 330 
                 CG 
                 TRP 
                 A 
                 38 
                 97.241 
                 38.121 
                 5.933 
                 1.00 
                 78.07 
                 C 
               
               
                 ATOM 
                 331 
                 CD1 
                 TRP 
                 A 
                 38 
                 97.750 
                 38.830 
                 6.979 
                 1.00 
                 79.20 
                 C 
               
               
                 ATOM 
                 332 
                 NE1 
                 TRP 
                 A 
                 38 
                 99.078 
                 38.532 
                 7.153 
                 1.00 
                 79.67 
                 N 
               
               
                 ATOM 
                 333 
                 CE2 
                 TRP 
                 A 
                 38 
                 99.453 
                 37.612 
                 6.211 
                 1.00 
                 78.00 
                 C 
               
               
                 ATOM 
                 334 
                 CD2 
                 TRP 
                 A 
                 38 
                 98.318 
                 37.326 
                 5.426 
                 1.00 
                 78.69 
                 C 
               
               
                 ATOM 
                 335 
                 CE3 
                 TRP 
                 A 
                 38 
                 98.435 
                 36.401 
                 4.383 
                 1.00 
                 81.00 
                 C 
               
               
                 ATOM 
                 336 
                 CZ3 
                 TRP 
                 A 
                 38 
                 99.666 
                 35.795 
                 4.164 
                 1.00 
                 80.23 
                 C 
               
               
                 ATOM 
                 337 
                 CH2 
                 TRP 
                 A 
                 38 
                 100.773 
                 36.102 
                 4.966 
                 1.00 
                 78.28 
                 C 
               
               
                 ATOM 
                 338 
                 CZ2 
                 TRP 
                 A 
                 38 
                 100.686 
                 37.002 
                 5.992 
                 1.00 
                 77.56 
                 C 
               
               
                 ATOM 
                 339 
                 C 
                 TRP 
                 A 
                 38 
                 95.084 
                 36.554 
                 7.184 
                 1.00 
                 76.24 
                 C 
               
               
                 ATOM 
                 340 
                 O 
                 TRP 
                 A 
                 38 
                 94.643 
                 37.316 
                 8.046 
                 1.00 
                 72.52 
                 O 
               
               
                 ATOM 
                 341 
                 N 
                 PHE 
                 A 
                 39 
                 95.648 
                 35.378 
                 7.461 
                 1.00 
                 77.18 
                 N 
               
               
                 ATOM 
                 342 
                 CA 
                 PHE 
                 A 
                 39 
                 95.744 
                 34.828 
                 8.819 
                 1.00 
                 76.64 
                 C 
               
               
                 ATOM 
                 343 
                 CB 
                 PHE 
                 A 
                 39 
                 96.652 
                 35.693 
                 9.705 
                 1.00 
                 77.48 
                 C 
               
               
                 ATOM 
                 344 
                 CG 
                 PHE 
                 A 
                 39 
                 98.059 
                 35.181 
                 9.814 
                 1.00 
                 78.53 
                 C 
               
               
                 ATOM 
                 345 
                 CD1 
                 PHE 
                 A 
                 39 
                 98.464 
                 34.469 
                 10.936 
                 1.00 
                 79.16 
                 C 
               
               
                 ATOM 
                 346 
                 CE1 
                 PHE 
                 A 
                 39 
                 99.762 
                 33.996 
                 11.045 
                 1.00 
                 79.01 
                 C 
               
               
                 ATOM 
                 347 
                 CZ 
                 PHE 
                 A 
                 39 
                 100.670 
                 34.227 
                 10.025 
                 1.00 
                 79.14 
                 C 
               
               
                 ATOM 
                 348 
                 CE2 
                 PHE 
                 A 
                 39 
                 100.278 
                 34.935 
                 8.902 
                 1.00 
                 78.45 
                 C 
               
               
                 ATOM 
                 349 
                 CD2 
                 PHE 
                 A 
                 39 
                 98.978 
                 35.407 
                 8.801 
                 1.00 
                 78.90 
                 C 
               
               
                 ATOM 
                 350 
                 C 
                 PHE 
                 A 
                 39 
                 94.382 
                 34.604 
                 9.482 
                 1.00 
                 76.52 
                 C 
               
               
                 ATOM 
                 351 
                 O 
                 PHE 
                 A 
                 39 
                 94.301 
                 34.448 
                 10.702 
                 1.00 
                 81.02 
                 O 
               
               
                 ATOM 
                 352 
                 N 
                 HIS 
                 A 
                 40 
                 93.327 
                 34.553 
                 8.669 
                 1.00 
                 74.90 
                 N 
               
               
                 ATOM 
                 353 
                 CA 
                 HIS 
                 A 
                 40 
                 91.956 
                 34.369 
                 9.146 
                 1.00 
                 74.06 
                 C 
               
               
                 ATOM 
                 354 
                 CB 
                 HIS 
                 A 
                 40 
                 91.817 
                 33.016 
                 9.857 
                 1.00 
                 69.89 
                 C 
               
               
                 ATOM 
                 355 
                 CG 
                 HIS 
                 A 
                 40 
                 90.460 
                 32.401 
                 9.730 
                 1.00 
                 66.79 
                 C 
               
               
                 ATOM 
                 356 
                 ND1 
                 HIS 
                 A 
                 40 
                 89.299 
                 33.085 
                 10.019 
                 1.00 
                 66.58 
                 N 
               
               
                 ATOM 
                 357 
                 CE1 
                 HIS 
                 A 
                 40 
                 88.262 
                 32.290 
                 9.821 
                 1.00 
                 65.80 
                 C 
               
               
                 ATOM 
                 358 
                 NE2 
                 HIS 
                 A 
                 40 
                 88.709 
                 31.111 
                 9.428 
                 1.00 
                 65.20 
                 N 
               
               
                 ATOM 
                 359 
                 CD2 
                 HIS 
                 A 
                 40 
                 90.081 
                 31.153 
                 9.365 
                 1.00 
                 65.32 
                 C 
               
               
                 ATOM 
                 360 
                 C 
                 HIS 
                 A 
                 40 
                 91.552 
                 35.513 
                 10.078 
                 1.00 
                 78.21 
                 C 
               
               
                 ATOM 
                 361 
                 O 
                 HIS 
                 A 
                 40 
                 90.708 
                 35.339 
                 10.959 
                 1.00 
                 79.42 
                 O 
               
               
                 ATOM 
                 362 
                 N 
                 ASN 
                 A 
                 41 
                 92.157 
                 36.683 
                 9.867 
                 1.00 
                 82.14 
                 N 
               
               
                 ATOM 
                 363 
                 CA 
                 ASN 
                 A 
                 41 
                 91.928 
                 37.861 
                 10.703 
                 1.00 
                 82.77 
                 C 
               
               
                 ATOM 
                 364 
                 CB 
                 ASN 
                 A 
                 41 
                 90.579 
                 38.500 
                 10.345 
                 1.00 
                 80.83 
                 C 
               
               
                 ATOM 
                 365 
                 CG 
                 ASN 
                 A 
                 41 
                 90.473 
                 39.946 
                 10.794 
                 1.00 
                 79.26 
                 C 
               
               
                 ATOM 
                 366 
                 OD1 
                 ASN 
                 A 
                 41 
                 91.480 
                 40.641 
                 10.938 
                 1.00 
                 78.80 
                 O 
               
               
                 ATOM 
                 367 
                 ND2 
                 ASN 
                 A 
                 41 
                 89.246 
                 40.413 
                 10.996 
                 1.00 
                 79.09 
                 N 
               
               
                 ATOM 
                 368 
                 C 
                 ASN 
                 A 
                 41 
                 92.010 
                 37.528 
                 12.198 
                 1.00 
                 84.66 
                 C 
               
               
                 ATOM 
                 369 
                 O 
                 ASN 
                 A 
                 41 
                 91.164 
                 37.952 
                 12.989 
                 1.00 
                 88.85 
                 O 
               
               
                 ATOM 
                 370 
                 N 
                 HIS 
                 A 
                 42 
                 93.030 
                 36.753 
                 12.568 
                 1.00 
                 84.35 
                 N 
               
               
                 ATOM 
                 371 
                 CA 
                 HIS 
                 A 
                 42 
                 93.252 
                 36.351 
                 13.959 
                 1.00 
                 84.97 
                 C 
               
               
                 ATOM 
                 372 
                 CB 
                 HIS 
                 A 
                 42 
                 93.240 
                 34.823 
                 14.093 
                 1.00 
                 83.97 
                 C 
               
               
                 ATOM 
                 373 
                 CG 
                 HIS 
                 A 
                 42 
                 91.890 
                 34.204 
                 13.916 
                 1.00 
                 83.92 
                 C 
               
               
                 ATOM 
                 374 
                 ND1 
                 HIS 
                 A 
                 42 
                 91.717 
                 32.943 
                 13.387 
                 1.00 
                 86.21 
                 N 
               
               
                 ATOM 
                 375 
                 CE1 
                 HIS 
                 A 
                 42 
                 90.428 
                 32.654 
                 13.355 
                 1.00 
                 84.60 
                 C 
               
               
                 ATOM 
                 376 
                 NE2 
                 HIS 
                 A 
                 42 
                 89.759 
                 33.686 
                 13.838 
                 1.00 
                 82.81 
                 N 
               
               
                 ATOM 
                 377 
                 CD2 
                 HIS 
                 A 
                 42 
                 90.650 
                 34.669 
                 14.195 
                 1.00 
                 82.87 
                 C 
               
               
                 ATOM 
                 378 
                 C 
                 HIS 
                 A 
                 42 
                 94.569 
                 36.885 
                 14.530 
                 1.00 
                 86.81 
                 C 
               
               
                 ATOM 
                 379 
                 O 
                 HIS 
                 A 
                 42 
                 95.054 
                 36.371 
                 15.539 
                 1.00 
                 88.94 
                 O 
               
               
                 ATOM 
                 380 
                 N 
                 LEU 
                 A 
                 43 
                 95.141 
                 37.915 
                 13.906 
                 1.00 
                 87.62 
                 N 
               
               
                 ATOM 
                 381 
                 CA 
                 LEU 
                 A 
                 43 
                 96.409 
                 38.480 
                 14.379 
                 1.00 
                 87.31 
                 C 
               
               
                 ATOM 
                 382 
                 CB 
                 LEU 
                 A 
                 43 
                 96.950 
                 39.518 
                 13.390 
                 1.00 
                 85.45 
                 C 
               
               
                 ATOM 
                 383 
                 CG 
                 LEU 
                 A 
                 43 
                 97.366 
                 38.975 
                 12.018 
                 1.00 
                 84.56 
                 C 
               
               
                 ATOM 
                 384 
                 CD1 
                 LEU 
                 A 
                 43 
                 97.778 
                 40.109 
                 11.092 
                 1.00 
                 84.45 
                 C 
               
               
                 ATOM 
                 385 
                 CD2 
                 LEU 
                 A 
                 43 
                 98.489 
                 37.957 
                 12.145 
                 1.00 
                 84.05 
                 C 
               
               
                 ATOM 
                 386 
                 C 
                 LEU 
                 A 
                 43 
                 96.285 
                 39.086 
                 15.781 
                 1.00 
                 90.04 
                 C 
               
               
                 ATOM 
                 387 
                 O 
                 LEU 
                 A 
                 43 
                 97.224 
                 39.010 
                 16.576 
                 1.00 
                 91.88 
                 O 
               
               
                 ATOM 
                 388 
                 N 
                 ASP 
                 A 
                 44 
                 95.122 
                 39.658 
                 16.089 
                 1.00 
                 90.94 
                 N 
               
               
                 ATOM 
                 389 
                 CA 
                 ASP 
                 A 
                 44 
                 94.872 
                 40.239 
                 17.413 
                 1.00 
                 90.81 
                 C 
               
               
                 ATOM 
                 390 
                 CB 
                 ASP 
                 A 
                 44 
                 93.751 
                 41.285 
                 17.342 
                 1.00 
                 91.78 
                 C 
               
               
                 ATOM 
                 391 
                 CG 
                 ASP 
                 A 
                 44 
                 94.126 
                 42.494 
                 16.497 
                 1.00 
                 93.05 
                 C 
               
               
                 ATOM 
                 392 
                 OD1 
                 ASP 
                 A 
                 44 
                 95.329 
                 42.704 
                 16.227 
                 1.00 
                 93.42 
                 O 
               
               
                 ATOM 
                 393 
                 OD2 
                 ASP 
                 A 
                 44 
                 93.210 
                 43.246 
                 16.105 
                 1.00 
                 95.74 
                 O 
               
               
                 ATOM 
                 394 
                 C 
                 ASP 
                 A 
                 44 
                 94.545 
                 39.189 
                 18.481 
                 1.00 
                 88.30 
                 C 
               
               
                 ATOM 
                 395 
                 O 
                 ASP 
                 A 
                 44 
                 94.294 
                 39.538 
                 19.634 
                 1.00 
                 92.18 
                 O 
               
               
                 ATOM 
                 396 
                 N 
                 TYR 
                 A 
                 45 
                 94.553 
                 37.912 
                 18.102 
                 1.00 
                 86.07 
                 N 
               
               
                 ATOM 
                 397 
                 CA 
                 TYR 
                 A 
                 45 
                 94.333 
                 36.810 
                 19.038 
                 1.00 
                 86.13 
                 C 
               
               
                 ATOM 
                 398 
                 CB 
                 TYR 
                 A 
                 45 
                 93.001 
                 36.116 
                 18.743 
                 1.00 
                 83.98 
                 C 
               
               
                 ATOM 
                 399 
                 CG 
                 TYR 
                 A 
                 45 
                 91.804 
                 37.000 
                 18.991 
                 1.00 
                 83.67 
                 C 
               
               
                 ATOM 
                 400 
                 CD1 
                 TYR 
                 A 
                 45 
                 91.391 
                 37.924 
                 18.038 
                 1.00 
                 83.99 
                 C 
               
               
                 ATOM 
                 401 
                 CE1 
                 TYR 
                 A 
                 45 
                 90.297 
                 38.743 
                 18.261 
                 1.00 
                 83.73 
                 C 
               
               
                 ATOM 
                 402 
                 CZ 
                 TYR 
                 A 
                 45 
                 89.601 
                 38.644 
                 19.450 
                 1.00 
                 83.17 
                 C 
               
               
                 ATOM 
                 403 
                 OH 
                 TYR 
                 A 
                 45 
                 88.513 
                 39.457 
                 19.672 
                 1.00 
                 82.14 
                 O 
               
               
                 ATOM 
                 404 
                 CE2 
                 TYR 
                 A 
                 45 
                 89.992 
                 37.733 
                 20.414 
                 1.00 
                 83.17 
                 C 
               
               
                 ATOM 
                 405 
                 CD2 
                 TYR 
                 A 
                 45 
                 91.089 
                 36.920 
                 20.182 
                 1.00 
                 82.66 
                 C 
               
               
                 ATOM 
                 406 
                 C 
                 TYR 
                 A 
                 45 
                 95.491 
                 35.818 
                 18.937 
                 1.00 
                 86.55 
                 C 
               
               
                 ATOM 
                 407 
                 O 
                 TYR 
                 A 
                 45 
                 95.294 
                 34.660 
                 18.566 
                 1.00 
                 86.50 
                 O 
               
               
                 ATOM 
                 408 
                 N 
                 PRO 
                 A 
                 46 
                 96.709 
                 36.270 
                 19.281 
                 1.00 
                 88.41 
                 N 
               
               
                 ATOM 
                 409 
                 CA 
                 PRO 
                 A 
                 46 
                 97.863 
                 35.396 
                 19.162 
                 1.00 
                 88.47 
                 C 
               
               
                 ATOM 
                 410 
                 CB 
                 PRO 
                 A 
                 46 
                 99.037 
                 36.370 
                 19.243 
                 1.00 
                 88.57 
                 C 
               
               
                 ATOM 
                 411 
                 CG 
                 PRO 
                 A 
                 46 
                 98.546 
                 37.474 
                 20.115 
                 1.00 
                 88.79 
                 C 
               
               
                 ATOM 
                 412 
                 CD 
                 PRO 
                 A 
                 46 
                 97.045 
                 37.515 
                 19.997 
                 1.00 
                 89.40 
                 C 
               
               
                 ATOM 
                 413 
                 C 
                 PRO 
                 A 
                 46 
                 97.936 
                 34.393 
                 20.304 
                 1.00 
                 89.24 
                 C 
               
               
                 ATOM 
                 414 
                 O 
                 PRO 
                 A 
                 46 
                 97.334 
                 34.616 
                 21.353 
                 1.00 
                 91.06 
                 O 
               
               
                 ATOM 
                 415 
                 N 
                 PRO 
                 A 
                 47 
                 98.682 
                 33.295 
                 20.108 
                 1.00 
                 89.74 
                 N 
               
               
                 ATOM 
                 416 
                 CA 
                 PRO 
                 A 
                 47 
                 98.854 
                 32.294 
                 21.153 
                 1.00 
                 89.39 
                 C 
               
               
                 ATOM 
                 417 
                 CB 
                 PRO 
                 A 
                 47 
                 99.518 
                 31.142 
                 20.405 
                 1.00 
                 89.86 
                 C 
               
               
                 ATOM 
                 418 
                 CG 
                 PRO 
                 A 
                 47 
                 100.352 
                 31.832 
                 19.379 
                 1.00 
                 89.43 
                 C 
               
               
                 ATOM 
                 419 
                 CD 
                 PRO 
                 A 
                 47 
                 99.525 
                 33.004 
                 18.932 
                 1.00 
                 89.34 
                 C 
               
               
                 ATOM 
                 420 
                 C 
                 PRO 
                 A 
                 47 
                 99.786 
                 32.818 
                 22.235 
                 1.00 
                 90.42 
                 C 
               
               
                 ATOM 
                 421 
                 O 
                 PRO 
                 A 
                 47 
                 100.293 
                 33.936 
                 22.120 
                 1.00 
                 90.12 
                 O 
               
               
                 ATOM 
                 422 
                 N 
                 HIS 
                 A 
                 48 
                 100.019 
                 32.023 
                 23.273 
                 1.00 
                 93.02 
                 N 
               
               
                 ATOM 
                 423 
                 CA 
                 HIS 
                 A 
                 48 
                 100.965 
                 32.424 
                 24.307 
                 1.00 
                 94.38 
                 C 
               
               
                 ATOM 
                 424 
                 CB 
                 HIS 
                 A 
                 48 
                 100.828 
                 31.565 
                 25.564 
                 1.00 
                 95.13 
                 C 
               
               
                 ATOM 
                 425 
                 CG 
                 HIS 
                 A 
                 48 
                 99.486 
                 31.671 
                 26.221 
                 1.00 
                 95.66 
                 C 
               
               
                 ATOM 
                 426 
                 ND1 
                 HIS 
                 A 
                 48 
                 98.803 
                 32.864 
                 26.331 
                 1.00 
                 97.19 
                 N 
               
               
                 ATOM 
                 427 
                 CE1 
                 HIS 
                 A 
                 48 
                 97.659 
                 32.658 
                 26.959 
                 1.00 
                 97.52 
                 C 
               
               
                 ATOM 
                 428 
                 NE2 
                 HIS 
                 A 
                 48 
                 97.581 
                 31.377 
                 27.272 
                 1.00 
                 97.13 
                 N 
               
               
                 ATOM 
                 429 
                 CD2 
                 HIS 
                 A 
                 48 
                 98.713 
                 30.738 
                 26.826 
                 1.00 
                 95.64 
                 C 
               
               
                 ATOM 
                 430 
                 C 
                 HIS 
                 A 
                 48 
                 102.376 
                 32.351 
                 23.718 
                 1.00 
                 96.28 
                 C 
               
               
                 ATOM 
                 431 
                 O 
                 HIS 
                 A 
                 48 
                 102.644 
                 31.505 
                 22.862 
                 1.00 
                 96.29 
                 O 
               
               
                 ATOM 
                 432 
                 N 
                 PRO 
                 A 
                 49 
                 103.281 
                 33.240 
                 24.166 
                 1.00 
                 97.64 
                 N 
               
               
                 ATOM 
                 433 
                 CA 
                 PRO 
                 A 
                 49 
                 104.614 
                 33.331 
                 23.557 
                 1.00 
                 98.49 
                 C 
               
               
                 ATOM 
                 434 
                 CB 
                 PRO 
                 A 
                 49 
                 105.323 
                 34.391 
                 24.414 
                 1.00 
                 99.83 
                 C 
               
               
                 ATOM 
                 435 
                 CG 
                 PRO 
                 A 
                 49 
                 104.229 
                 35.170 
                 25.054 
                 1.00 
                 98.41 
                 C 
               
               
                 ATOM 
                 436 
                 CD 
                 PRO 
                 A 
                 49 
                 103.136 
                 34.177 
                 25.295 
                 1.00 
                 97.68 
                 C 
               
               
                 ATOM 
                 437 
                 C 
                 PRO 
                 A 
                 49 
                 105.431 
                 32.036 
                 23.539 
                 1.00 
                 97.48 
                 C 
               
               
                 ATOM 
                 438 
                 O 
                 PRO 
                 A 
                 49 
                 106.244 
                 31.849 
                 22.636 
                 1.00 
                 96.07 
                 O 
               
               
                 ATOM 
                 439 
                 N 
                 GLY 
                 A 
                 50 
                 105.216 
                 31.159 
                 24.519 
                 1.00 
                 97.60 
                 N 
               
               
                 ATOM 
                 440 
                 CA 
                 GLY 
                 A 
                 50 
                 105.978 
                 29.912 
                 24.628 
                 1.00 
                 96.66 
                 C 
               
               
                 ATOM 
                 441 
                 C 
                 GLY 
                 A 
                 50 
                 105.441 
                 28.715 
                 23.858 
                 1.00 
                 94.24 
                 C 
               
               
                 ATOM 
                 442 
                 O 
                 GLY 
                 A 
                 50 
                 106.114 
                 27.688 
                 23.777 
                 1.00 
                 96.57 
                 O 
               
               
                 ATOM 
                 443 
                 N 
                 ASP 
                 A 
                 51 
                 104.238 
                 28.835 
                 23.296 
                 1.00 
                 91.17 
                 N 
               
               
                 ATOM 
                 444 
                 CA 
                 ASP 
                 A 
                 51 
                 103.607 
                 27.733 
                 22.562 
                 1.00 
                 88.43 
                 C 
               
               
                 ATOM 
                 445 
                 CB 
                 ASP 
                 A 
                 51 
                 102.084 
                 27.821 
                 22.685 
                 1.00 
                 88.07 
                 C 
               
               
                 ATOM 
                 446 
                 CG 
                 ASP 
                 A 
                 51 
                 101.602 
                 27.681 
                 24.121 
                 1.00 
                 88.98 
                 C 
               
               
                 ATOM 
                 447 
                 OD1 
                 ASP 
                 A 
                 51 
                 102.338 
                 27.107 
                 24.952 
                 1.00 
                 87.99 
                 O 
               
               
                 ATOM 
                 448 
                 OD2 
                 ASP 
                 A 
                 51 
                 100.477 
                 28.141 
                 24.416 
                 1.00 
                 88.52 
                 O 
               
               
                 ATOM 
                 449 
                 C 
                 ASP 
                 A 
                 51 
                 104.007 
                 27.717 
                 21.081 
                 1.00 
                 87.45 
                 C 
               
               
                 ATOM 
                 450 
                 O 
                 ASP 
                 A 
                 51 
                 103.668 
                 28.632 
                 20.328 
                 1.00 
                 82.48 
                 O 
               
               
                 ATOM 
                 451 
                 N 
                 PHE 
                 A 
                 52 
                 104.729 
                 26.669 
                 20.681 
                 1.00 
                 86.67 
                 N 
               
               
                 ATOM 
                 452 
                 CA 
                 PHE 
                 A 
                 52 
                 105.177 
                 26.489 
                 19.299 
                 1.00 
                 86.78 
                 C 
               
               
                 ATOM 
                 453 
                 CB 
                 PHE 
                 A 
                 52 
                 106.681 
                 26.747 
                 19.178 
                 1.00 
                 88.12 
                 C 
               
               
                 ATOM 
                 454 
                 CG 
                 PHE 
                 A 
                 52 
                 107.071 
                 28.187 
                 19.330 
                 1.00 
                 89.61 
                 C 
               
               
                 ATOM 
                 455 
                 CD1 
                 PHE 
                 A 
                 52 
                 107.381 
                 28.709 
                 20.577 
                 1.00 
                 90.55 
                 C 
               
               
                 ATOM 
                 456 
                 CE1 
                 PHE 
                 A 
                 52 
                 107.750 
                 30.034 
                 20.716 
                 1.00 
                 91.55 
                 C 
               
               
                 ATOM 
                 457 
                 CZ 
                 PHE 
                 A 
                 52 
                 107.815 
                 30.856 
                 19.604 
                 1.00 
                 92.08 
                 C 
               
               
                 ATOM 
                 458 
                 CE2 
                 PHE 
                 A 
                 52 
                 107.513 
                 30.347 
                 18.354 
                 1.00 
                 90.65 
                 C 
               
               
                 ATOM 
                 459 
                 CD2 
                 PHE 
                 A 
                 52 
                 107.148 
                 29.019 
                 18.222 
                 1.00 
                 90.14 
                 C 
               
               
                 ATOM 
                 460 
                 C 
                 PHE 
                 A 
                 52 
                 104.900 
                 25.073 
                 18.806 
                 1.00 
                 86.43 
                 C 
               
               
                 ATOM 
                 461 
                 O 
                 PHE 
                 A 
                 52 
                 104.956 
                 24.116 
                 19.580 
                 1.00 
                 89.33 
                 O 
               
               
                 ATOM 
                 462 
                 N 
                 PHE 
                 A 
                 53 
                 104.608 
                 24.955 
                 17.514 
                 1.00 
                 84.53 
                 N 
               
               
                 ATOM 
                 463 
                 CA 
                 PHE 
                 A 
                 53 
                 104.450 
                 23.658 
                 16.861 
                 1.00 
                 82.72 
                 C 
               
               
                 ATOM 
                 464 
                 CB 
                 PHE 
                 A 
                 53 
                 103.408 
                 23.744 
                 15.744 
                 1.00 
                 79.11 
                 C 
               
               
                 ATOM 
                 465 
                 CG 
                 PHE 
                 A 
                 53 
                 103.052 
                 22.415 
                 15.135 
                 1.00 
                 74.50 
                 C 
               
               
                 ATOM 
                 466 
                 CD1 
                 PHE 
                 A 
                 53 
                 101.884 
                 21.762 
                 15.500 
                 1.00 
                 72.03 
                 C 
               
               
                 ATOM 
                 467 
                 CE1 
                 PHE 
                 A 
                 53 
                 101.551 
                 20.539 
                 14.944 
                 1.00 
                 70.56 
                 C 
               
               
                 ATOM 
                 468 
                 CZ 
                 PHE 
                 A 
                 53 
                 102.389 
                 19.954 
                 14.012 
                 1.00 
                 71.23 
                 C 
               
               
                 ATOM 
                 469 
                 CE2 
                 PHE 
                 A 
                 53 
                 103.556 
                 20.594 
                 13.636 
                 1.00 
                 71.89 
                 C 
               
               
                 ATOM 
                 470 
                 CD2 
                 PHE 
                 A 
                 53 
                 103.883 
                 21.817 
                 14.194 
                 1.00 
                 73.25 
                 C 
               
               
                 ATOM 
                 471 
                 C 
                 PHE 
                 A 
                 53 
                 105.820 
                 23.292 
                 16.290 
                 1.00 
                 83.28 
                 C 
               
               
                 ATOM 
                 472 
                 O 
                 PHE 
                 A 
                 53 
                 106.380 
                 24.038 
                 15.488 
                 1.00 
                 82.27 
                 O 
               
               
                 ATOM 
                 473 
                 N 
                 ASP 
                 A 
                 54 
                 106.356 
                 22.147 
                 16.700 
                 1.00 
                 84.85 
                 N 
               
               
                 ATOM 
                 474 
                 CA 
                 ASP 
                 A 
                 54 
                 107.699 
                 21.737 
                 16.288 
                 1.00 
                 85.30 
                 C 
               
               
                 ATOM 
                 475 
                 CB 
                 ASP 
                 A 
                 54 
                 108.404 
                 21.003 
                 17.436 
                 1.00 
                 87.15 
                 C 
               
               
                 ATOM 
                 476 
                 CG 
                 ASP 
                 A 
                 54 
                 108.726 
                 21.918 
                 18.607 
                 1.00 
                 88.60 
                 C 
               
               
                 ATOM 
                 477 
                 OD1 
                 ASP 
                 A 
                 54 
                 109.024 
                 23.113 
                 18.382 
                 1.00 
                 87.90 
                 O 
               
               
                 ATOM 
                 478 
                 OD2 
                 ASP 
                 A 
                 54 
                 108.698 
                 21.435 
                 19.758 
                 1.00 
                 93.39 
                 O 
               
               
                 ATOM 
                 479 
                 C 
                 ASP 
                 A 
                 54 
                 107.708 
                 20.870 
                 15.029 
                 1.00 
                 83.18 
                 C 
               
               
                 ATOM 
                 480 
                 O 
                 ASP 
                 A 
                 54 
                 106.981 
                 19.880 
                 14.941 
                 1.00 
                 83.58 
                 O 
               
               
                 ATOM 
                 481 
                 N 
                 PHE 
                 A 
                 55 
                 108.541 
                 21.258 
                 14.065 
                 1.00 
                 80.53 
                 N 
               
               
                 ATOM 
                 482 
                 CA 
                 PHE 
                 A 
                 55 
                 108.739 
                 20.499 
                 12.832 
                 1.00 
                 78.93 
                 C 
               
               
                 ATOM 
                 483 
                 CB 
                 PHE 
                 A 
                 55 
                 108.573 
                 21.403 
                 11.604 
                 1.00 
                 79.62 
                 C 
               
               
                 ATOM 
                 484 
                 CG 
                 PHE 
                 A 
                 55 
                 107.140 
                 21.707 
                 11.263 
                 1.00 
                 78.94 
                 C 
               
               
                 ATOM 
                 485 
                 CD1 
                 PHE 
                 A 
                 55 
                 106.328 
                 20.729 
                 10.701 
                 1.00 
                 78.40 
                 C 
               
               
                 ATOM 
                 486 
                 CE1 
                 PHE 
                 A 
                 55 
                 105.009 
                 20.997 
                 10.388 
                 1.00 
                 76.98 
                 C 
               
               
                 ATOM 
                 487 
                 CZ 
                 PHE 
                 A 
                 55 
                 104.486 
                 22.254 
                 10.624 
                 1.00 
                 77.19 
                 C 
               
               
                 ATOM 
                 488 
                 CE2 
                 PHE 
                 A 
                 55 
                 105.283 
                 23.242 
                 11.175 
                 1.00 
                 77.28 
                 C 
               
               
                 ATOM 
                 489 
                 CD2 
                 PHE 
                 A 
                 55 
                 106.603 
                 22.967 
                 11.492 
                 1.00 
                 77.85 
                 C 
               
               
                 ATOM 
                 490 
                 C 
                 PHE 
                 A 
                 55 
                 110.137 
                 19.882 
                 12.844 
                 1.00 
                 77.06 
                 C 
               
               
                 ATOM 
                 491 
                 O 
                 PHE 
                 A 
                 55 
                 111.126 
                 20.594 
                 12.670 
                 1.00 
                 76.91 
                 O 
               
               
                 ATOM 
                 492 
                 N 
                 PRO 
                 A 
                 56 
                 110.228 
                 18.556 
                 13.051 
                 1.00 
                 75.75 
                 N 
               
               
                 ATOM 
                 493 
                 CA 
                 PRO 
                 A 
                 56 
                 111.536 
                 17.916 
                 13.097 
                 1.00 
                 77.64 
                 C 
               
               
                 ATOM 
                 494 
                 CB 
                 PRO 
                 A 
                 56 
                 111.263 
                 16.636 
                 13.886 
                 1.00 
                 77.83 
                 C 
               
               
                 ATOM 
                 495 
                 CG 
                 PRO 
                 A 
                 56 
                 109.837 
                 16.308 
                 13.603 
                 1.00 
                 76.68 
                 C 
               
               
                 ATOM 
                 496 
                 CD 
                 PRO 
                 A 
                 56 
                 109.136 
                 17.579 
                 13.209 
                 1.00 
                 76.19 
                 C 
               
               
                 ATOM 
                 497 
                 C 
                 PRO 
                 A 
                 56 
                 112.080 
                 17.594 
                 11.707 
                 1.00 
                 80.24 
                 C 
               
               
                 ATOM 
                 498 
                 O 
                 PRO 
                 A 
                 56 
                 111.481 
                 16.802 
                 10.979 
                 1.00 
                 83.61 
                 O 
               
               
                 ATOM 
                 499 
                 N 
                 ALA 
                 A 
                 57 
                 113.214 
                 18.200 
                 11.359 
                 1.00 
                 80.81 
                 N 
               
               
                 ATOM 
                 500 
                 CA 
                 ALA 
                 A 
                 57 
                 113.845 
                 17.992 
                 10.058 
                 1.00 
                 79.94 
                 C 
               
               
                 ATOM 
                 501 
                 CB 
                 ALA 
                 A 
                 57 
                 115.173 
                 18.730 
                 9.993 
                 1.00 
                 79.03 
                 C 
               
               
                 ATOM 
                 502 
                 C 
                 ALA 
                 A 
                 57 
                 114.053 
                 16.510 
                 9.766 
                 1.00 
                 81.02 
                 C 
               
               
                 ATOM 
                 503 
                 O 
                 ALA 
                 A 
                 57 
                 114.479 
                 15.753 
                 10.636 
                 1.00 
                 82.40 
                 O 
               
               
                 ATOM 
                 504 
                 N 
                 GLY 
                 A 
                 58 
                 113.730 
                 16.103 
                 8.541 
                 1.00 
                 83.86 
                 N 
               
               
                 ATOM 
                 505 
                 CA 
                 GLY 
                 A 
                 58 
                 113.888 
                 14.716 
                 8.109 
                 1.00 
                 84.69 
                 C 
               
               
                 ATOM 
                 506 
                 C 
                 GLY 
                 A 
                 58 
                 112.937 
                 13.736 
                 8.771 
                 1.00 
                 84.18 
                 C 
               
               
                 ATOM 
                 507 
                 O 
                 GLY 
                 A 
                 58 
                 113.135 
                 12.524 
                 8.674 
                 1.00 
                 85.98 
                 O 
               
               
                 ATOM 
                 508 
                 N 
                 LYS 
                 A 
                 59 
                 111.899 
                 14.255 
                 9.427 
                 1.00 
                 82.88 
                 N 
               
               
                 ATOM 
                 509 
                 CA 
                 LYS 
                 A 
                 59 
                 110.931 
                 13.430 
                 10.147 
                 1.00 
                 83.70 
                 C 
               
               
                 ATOM 
                 510 
                 CB 
                 LYS 
                 A 
                 59 
                 111.279 
                 13.390 
                 11.639 
                 1.00 
                 87.21 
                 C 
               
               
                 ATOM 
                 511 
                 CG 
                 LYS 
                 A 
                 59 
                 112.457 
                 12.494 
                 11.985 
                 1.00 
                 90.93 
                 C 
               
               
                 ATOM 
                 512 
                 CD 
                 LYS 
                 A 
                 59 
                 112.880 
                 12.671 
                 13.433 
                 1.00 
                 95.35 
                 C 
               
               
                 ATOM 
                 513 
                 CE 
                 LYS 
                 A 
                 59 
                 113.889 
                 11.613 
                 13.850 
                 1.00 
                 100.46 
                 C 
               
               
                 ATOM 
                 514 
                 NZ 
                 LYS 
                 A 
                 59 
                 114.320 
                 11.783 
                 15.267 
                 1.00 
                 103.42 
                 N 
               
               
                 ATOM 
                 515 
                 C 
                 LYS 
                 A 
                 59 
                 109.507 
                 13.947 
                 9.962 
                 1.00 
                 81.27 
                 C 
               
               
                 ATOM 
                 516 
                 O 
                 LYS 
                 A 
                 59 
                 109.292 
                 15.090 
                 9.554 
                 1.00 
                 79.60 
                 O 
               
               
                 ATOM 
                 517 
                 N 
                 ALA 
                 A 
                 60 
                 108.540 
                 13.091 
                 10.271 
                 1.00 
                 79.91 
                 N 
               
               
                 ATOM 
                 518 
                 CA 
                 ALA 
                 A 
                 60 
                 107.128 
                 13.437 
                 10.156 
                 1.00 
                 79.46 
                 C 
               
               
                 ATOM 
                 519 
                 CB 
                 ALA 
                 A 
                 60 
                 106.282 
                 12.173 
                 10.104 
                 1.00 
                 81.71 
                 C 
               
               
                 ATOM 
                 520 
                 C 
                 ALA 
                 A 
                 60 
                 106.678 
                 14.321 
                 11.315 
                 1.00 
                 77.96 
                 C 
               
               
                 ATOM 
                 521 
                 O 
                 ALA 
                 A 
                 60 
                 107.222 
                 14.246 
                 12.418 
                 1.00 
                 81.06 
                 O 
               
               
                 ATOM 
                 522 
                 N 
                 ALA 
                 A 
                 61 
                 105.681 
                 15.158 
                 11.049 
                 1.00 
                 74.15 
                 N 
               
               
                 ATOM 
                 523 
                 CA 
                 ALA 
                 A 
                 61 
                 105.096 
                 16.029 
                 12.056 
                 1.00 
                 72.68 
                 C 
               
               
                 ATOM 
                 524 
                 CB 
                 ALA 
                 A 
                 61 
                 105.499 
                 17.470 
                 11.806 
                 1.00 
                 71.45 
                 C 
               
               
                 ATOM 
                 525 
                 C 
                 ALA 
                 A 
                 61 
                 103.584 
                 15.879 
                 11.991 
                 1.00 
                 73.76 
                 C 
               
               
                 ATOM 
                 526 
                 O 
                 ALA 
                 A 
                 61 
                 102.958 
                 16.323 
                 11.031 
                 1.00 
                 76.05 
                 O 
               
               
                 ATOM 
                 527 
                 N 
                 THR 
                 A 
                 62 
                 102.998 
                 15.252 
                 13.007 
                 1.00 
                 74.78 
                 N 
               
               
                 ATOM 
                 528 
                 CA 
                 THR 
                 A 
                 62 
                 101.556 
                 15.021 
                 13.029 
                 1.00 
                 74.22 
                 C 
               
               
                 ATOM 
                 529 
                 CB 
                 THR 
                 A 
                 62 
                 101.182 
                 13.889 
                 13.999 
                 1.00 
                 74.44 
                 C 
               
               
                 ATOM 
                 530 
                 OG1 
                 THR 
                 A 
                 62 
                 101.914 
                 12.706 
                 13.655 
                 1.00 
                 77.29 
                 O 
               
               
                 ATOM 
                 531 
                 CG2 
                 THR 
                 A 
                 62 
                 99.690 
                 13.590 
                 13.929 
                 1.00 
                 74.77 
                 C 
               
               
                 ATOM 
                 532 
                 C 
                 THR 
                 A 
                 62 
                 100.789 
                 16.284 
                 13.415 
                 1.00 
                 73.32 
                 C 
               
               
                 ATOM 
                 533 
                 O 
                 THR 
                 A 
                 62 
                 101.075 
                 16.906 
                 14.437 
                 1.00 
                 73.85 
                 O 
               
               
                 ATOM 
                 534 
                 N 
                 ALA 
                 A 
                 63 
                 99.818 
                 16.648 
                 12.581 
                 1.00 
                 71.65 
                 N 
               
               
                 ATOM 
                 535 
                 CA 
                 ALA 
                 A 
                 63 
                 98.959 
                 17.799 
                 12.812 
                 1.00 
                 71.44 
                 C 
               
               
                 ATOM 
                 536 
                 CB 
                 ALA 
                 A 
                 63 
                 99.055 
                 18.763 
                 11.646 
                 1.00 
                 72.36 
                 C 
               
               
                 ATOM 
                 537 
                 C 
                 ALA 
                 A 
                 63 
                 97.529 
                 17.313 
                 12.972 
                 1.00 
                 72.07 
                 C 
               
               
                 ATOM 
                 538 
                 O 
                 ALA 
                 A 
                 63 
                 97.175 
                 16.254 
                 12.454 
                 1.00 
                 72.86 
                 O 
               
               
                 ATOM 
                 539 
                 N 
                 GLU 
                 A 
                 64 
                 96.713 
                 18.080 
                 13.691 
                 1.00 
                 73.76 
                 N 
               
               
                 ATOM 
                 540 
                 CA 
                 GLU 
                 A 
                 64 
                 95.314 
                 17.714 
                 13.916 
                 1.00 
                 74.96 
                 C 
               
               
                 ATOM 
                 541 
                 CB 
                 GLU 
                 A 
                 64 
                 94.972 
                 17.740 
                 15.404 
                 1.00 
                 76.45 
                 C 
               
               
                 ATOM 
                 542 
                 CG 
                 GLU 
                 A 
                 64 
                 95.780 
                 16.747 
                 16.224 
                 1.00 
                 79.88 
                 C 
               
               
                 ATOM 
                 543 
                 CD 
                 GLU 
                 A 
                 64 
                 95.271 
                 16.604 
                 17.645 
                 1.00 
                 83.26 
                 C 
               
               
                 ATOM 
                 544 
                 OE1 
                 GLU 
                 A 
                 64 
                 94.084 
                 16.260 
                 17.822 
                 1.00 
                 84.32 
                 O 
               
               
                 ATOM 
                 545 
                 OE2 
                 GLU 
                 A 
                 64 
                 96.063 
                 16.818 
                 18.587 
                 1.00 
                 85.29 
                 O 
               
               
                 ATOM 
                 546 
                 C 
                 GLU 
                 A 
                 64 
                 94.378 
                 18.630 
                 13.139 
                 1.00 
                 74.74 
                 C 
               
               
                 ATOM 
                 547 
                 O 
                 GLU 
                 A 
                 64 
                 94.387 
                 19.850 
                 13.323 
                 1.00 
                 74.92 
                 O 
               
               
                 ATOM 
                 548 
                 N 
                 LEU 
                 A 
                 65 
                 93.577 
                 18.024 
                 12.268 
                 1.00 
                 73.51 
                 N 
               
               
                 ATOM 
                 549 
                 CA 
                 LEU 
                 A 
                 65 
                 92.629 
                 18.744 
                 11.431 
                 1.00 
                 71.37 
                 C 
               
               
                 ATOM 
                 550 
                 CB 
                 LEU 
                 A 
                 65 
                 92.931 
                 18.473 
                 9.956 
                 1.00 
                 71.01 
                 C 
               
               
                 ATOM 
                 551 
                 CG 
                 LEU 
                 A 
                 65 
                 94.395 
                 18.637 
                 9.526 
                 1.00 
                 71.64 
                 C 
               
               
                 ATOM 
                 552 
                 CD1 
                 LEU 
                 A 
                 65 
                 94.593 
                 18.148 
                 8.102 
                 1.00 
                 73.33 
                 C 
               
               
                 ATOM 
                 553 
                 CD2 
                 LEU 
                 A 
                 65 
                 94.859 
                 20.078 
                 9.664 
                 1.00 
                 71.74 
                 C 
               
               
                 ATOM 
                 554 
                 C 
                 LEU 
                 A 
                 65 
                 91.232 
                 18.257 
                 11.782 
                 1.00 
                 69.60 
                 C 
               
               
                 ATOM 
                 555 
                 O 
                 LEU 
                 A 
                 65 
                 90.983 
                 17.052 
                 11.773 
                 1.00 
                 68.72 
                 O 
               
               
                 ATOM 
                 556 
                 N 
                 ALA 
                 A 
                 66 
                 90.328 
                 19.181 
                 12.104 
                 1.00 
                 69.80 
                 N 
               
               
                 ATOM 
                 557 
                 CA 
                 ALA 
                 A 
                 66 
                 88.965 
                 18.808 
                 12.481 
                 1.00 
                 71.86 
                 C 
               
               
                 ATOM 
                 558 
                 CB 
                 ALA 
                 A 
                 66 
                 88.952 
                 18.233 
                 13.893 
                 1.00 
                 72.50 
                 C 
               
               
                 ATOM 
                 559 
                 C 
                 ALA 
                 A 
                 66 
                 87.972 
                 19.962 
                 12.377 
                 1.00 
                 75.05 
                 C 
               
               
                 ATOM 
                 560 
                 O 
                 ALA 
                 A 
                 66 
                 88.357 
                 21.130 
                 12.313 
                 1.00 
                 76.83 
                 O 
               
               
                 ATOM 
                 561 
                 N 
                 CYS 
                 A 
                 67 
                 86.689 
                 19.611 
                 12.367 
                 1.00 
                 79.66 
                 N 
               
               
                 ATOM 
                 562 
                 CA 
                 CYS 
                 A 
                 67 
                 85.606 
                 20.587 
                 12.285 
                 1.00 
                 84.59 
                 C 
               
               
                 ATOM 
                 563 
                 CB 
                 CYS 
                 A 
                 67 
                 84.324 
                 19.913 
                 11.791 
                 1.00 
                 89.06 
                 C 
               
               
                 ATOM 
                 564 
                 SG 
                 CYS 
                 A 
                 67 
                 83.623 
                 18.703 
                 12.944 
                 1.00 
                 99.46 
                 S 
               
               
                 ATOM 
                 565 
                 C 
                 CYS 
                 A 
                 67 
                 85.349 
                 21.253 
                 13.632 
                 1.00 
                 85.01 
                 C 
               
               
                 ATOM 
                 566 
                 O 
                 CYS 
                 A 
                 67 
                 84.738 
                 22.321 
                 13.691 
                 1.00 
                 85.07 
                 O 
               
               
                 ATOM 
                 567 
                 N 
                 ASN 
                 A 
                 68 
                 85.799 
                 20.609 
                 14.707 
                 1.00 
                 89.37 
                 N 
               
               
                 ATOM 
                 568 
                 CA 
                 ASN 
                 A 
                 68 
                 85.644 
                 21.151 
                 16.053 
                 1.00 
                 93.19 
                 C 
               
               
                 ATOM 
                 569 
                 CB 
                 ASN 
                 A 
                 68 
                 84.401 
                 20.587 
                 16.750 
                 1.00 
                 98.47 
                 C 
               
               
                 ATOM 
                 570 
                 CG 
                 ASN 
                 A 
                 68 
                 83.562 
                 21.678 
                 17.382 
                 1.00 
                 106.32 
                 C 
               
               
                 ATOM 
                 571 
                 OD1 
                 ASN 
                 A 
                 68 
                 84.040 
                 22.438 
                 18.231 
                 1.00 
                 111.29 
                 O 
               
               
                 ATOM 
                 572 
                 ND2 
                 ASN 
                 A 
                 68 
                 82.315 
                 21.785 
                 16.947 
                 1.00 
                 110.61 
                 N 
               
               
                 ATOM 
                 573 
                 C 
                 ASN 
                 A 
                 68 
                 86.866 
                 20.854 
                 16.898 
                 1.00 
                 89.54 
                 C 
               
               
                 ATOM 
                 574 
                 O 
                 ASN 
                 A 
                 68 
                 87.495 
                 19.803 
                 16.752 
                 1.00 
                 91.68 
                 O 
               
               
                 ATOM 
                 575 
                 N 
                 LYS 
                 A 
                 69 
                 87.186 
                 21.778 
                 17.795 
                 1.00 
                 86.26 
                 N 
               
               
                 ATOM 
                 576 
                 CA 
                 LYS 
                 A 
                 69 
                 88.306 
                 21.598 
                 18.706 
                 1.00 
                 84.37 
                 C 
               
               
                 ATOM 
                 577 
                 CB 
                 LYS 
                 A 
                 69 
                 88.599 
                 22.902 
                 19.446 
                 1.00 
                 84.78 
                 C 
               
               
                 ATOM 
                 578 
                 CG 
                 LYS 
                 A 
                 69 
                 89.835 
                 22.845 
                 20.325 
                 1.00 
                 85.39 
                 C 
               
               
                 ATOM 
                 579 
                 CD 
                 LYS 
                 A 
                 69 
                 90.389 
                 24.228 
                 20.637 
                 1.00 
                 86.09 
                 C 
               
               
                 ATOM 
                 580 
                 CE 
                 LYS 
                 A 
                 69 
                 89.394 
                 25.097 
                 21.390 
                 1.00 
                 86.95 
                 C 
               
               
                 ATOM 
                 581 
                 NZ 
                 LYS 
                 A 
                 69 
                 89.991 
                 26.410 
                 21.760 
                 1.00 
                 87.92 
                 N 
               
               
                 ATOM 
                 582 
                 C 
                 LYS 
                 A 
                 69 
                 88.029 
                 20.447 
                 19.683 
                 1.00 
                 82.18 
                 C 
               
               
                 ATOM 
                 583 
                 O 
                 LYS 
                 A 
                 69 
                 88.958 
                 19.835 
                 20.203 
                 1.00 
                 82.98 
                 O 
               
               
                 ATOM 
                 584 
                 N 
                 GLY 
                 A 
                 70 
                 86.750 
                 20.150 
                 19.913 
                 1.00 
                 80.13 
                 N 
               
               
                 ATOM 
                 585 
                 CA 
                 GLY 
                 A 
                 70 
                 86.350 
                 19.014 
                 20.742 
                 1.00 
                 78.14 
                 C 
               
               
                 ATOM 
                 586 
                 C 
                 GLY 
                 A 
                 70 
                 86.766 
                 17.677 
                 20.153 
                 1.00 
                 77.52 
                 C 
               
               
                 ATOM 
                 587 
                 O 
                 GLY 
                 A 
                 70 
                 86.987 
                 16.712 
                 20.885 
                 1.00 
                 76.75 
                 O 
               
               
                 ATOM 
                 588 
                 N 
                 ALA 
                 A 
                 71 
                 86.878 
                 17.622 
                 18.826 
                 1.00 
                 78.12 
                 N 
               
               
                 ATOM 
                 589 
                 CA 
                 ALA 
                 A 
                 71 
                 87.305 
                 16.410 
                 18.126 
                 1.00 
                 75.95 
                 C 
               
               
                 ATOM 
                 590 
                 CB 
                 ALA 
                 A 
                 71 
                 86.765 
                 16.412 
                 16.704 
                 1.00 
                 77.32 
                 C 
               
               
                 ATOM 
                 591 
                 C 
                 ALA 
                 A 
                 71 
                 88.826 
                 16.241 
                 18.109 
                 1.00 
                 75.03 
                 C 
               
               
                 ATOM 
                 592 
                 O 
                 ALA 
                 A 
                 71 
                 89.329 
                 15.288 
                 17.521 
                 1.00 
                 77.75 
                 O 
               
               
                 ATOM 
                 593 
                 N 
                 THR 
                 A 
                 72 
                 89.552 
                 17.157 
                 18.748 
                 1.00 
                 75.74 
                 N 
               
               
                 ATOM 
                 594 
                 CA 
                 THR 
                 A 
                 72 
                 91.009 
                 17.092 
                 18.825 
                 1.00 
                 77.19 
                 C 
               
               
                 ATOM 
                 595 
                 CB 
                 THR 
                 A 
                 72 
                 91.642 
                 18.360 
                 18.225 
                 1.00 
                 77.47 
                 C 
               
               
                 ATOM 
                 596 
                 OG1 
                 THR 
                 A 
                 72 
                 91.168 
                 19.515 
                 18.927 
                 1.00 
                 74.39 
                 O 
               
               
                 ATOM 
                 597 
                 CG2 
                 THR 
                 A 
                 72 
                 91.290 
                 18.485 
                 16.752 
                 1.00 
                 80.25 
                 C 
               
               
                 ATOM 
                 598 
                 C 
                 THR 
                 A 
                 72 
                 91.464 
                 16.948 
                 20.276 
                 1.00 
                 80.88 
                 C 
               
               
                 ATOM 
                 599 
                 O 
                 THR 
                 A 
                 72 
                 90.646 
                 16.952 
                 21.196 
                 1.00 
                 82.69 
                 O 
               
               
                 ATOM 
                 600 
                 N 
                 THR 
                 A 
                 73 
                 92.776 
                 16.827 
                 20.471 
                 1.00 
                 83.90 
                 N 
               
               
                 ATOM 
                 601 
                 CA 
                 THR 
                 A 
                 73 
                 93.373 
                 16.708 
                 21.805 
                 1.00 
                 84.61 
                 C 
               
               
                 ATOM 
                 602 
                 CB 
                 THR 
                 A 
                 73 
                 94.884 
                 16.416 
                 21.707 
                 1.00 
                 85.56 
                 C 
               
               
                 ATOM 
                 603 
                 OG1 
                 THR 
                 A 
                 73 
                 95.130 
                 15.511 
                 20.625 
                 1.00 
                 85.62 
                 O 
               
               
                 ATOM 
                 604 
                 CG2 
                 THR 
                 A 
                 73 
                 95.410 
                 15.811 
                 23.004 
                 1.00 
                 88.69 
                 C 
               
               
                 ATOM 
                 605 
                 C 
                 THR 
                 A 
                 73 
                 93.189 
                 17.985 
                 22.634 
                 1.00 
                 84.43 
                 C 
               
               
                 ATOM 
                 606 
                 O 
                 THR 
                 A 
                 73 
                 93.260 
                 17.951 
                 23.863 
                 1.00 
                 87.77 
                 O 
               
               
                 ATOM 
                 607 
                 N 
                 TRP 
                 A 
                 74 
                 92.934 
                 19.102 
                 21.958 
                 1.00 
                 82.29 
                 N 
               
               
                 ATOM 
                 608 
                 CA 
                 TRP 
                 A 
                 74 
                 92.762 
                 20.392 
                 22.617 
                 1.00 
                 80.19 
                 C 
               
               
                 ATOM 
                 609 
                 CB 
                 TRP 
                 A 
                 74 
                 93.267 
                 21.503 
                 21.692 
                 1.00 
                 81.10 
                 C 
               
               
                 ATOM 
                 610 
                 CG 
                 TRP 
                 A 
                 74 
                 94.650 
                 21.231 
                 21.197 
                 1.00 
                 81.68 
                 C 
               
               
                 ATOM 
                 611 
                 CD1 
                 TRP 
                 A 
                 74 
                 95.000 
                 20.674 
                 20.003 
                 1.00 
                 80.85 
                 C 
               
               
                 ATOM 
                 612 
                 NE1 
                 TRP 
                 A 
                 74 
                 96.365 
                 20.556 
                 19.917 
                 1.00 
                 82.91 
                 N 
               
               
                 ATOM 
                 613 
                 CE2 
                 TRP 
                 A 
                 74 
                 96.923 
                 21.033 
                 21.073 
                 1.00 
                 83.06 
                 C 
               
               
                 ATOM 
                 614 
                 CD2 
                 TRP 
                 A 
                 74 
                 95.870 
                 21.458 
                 21.907 
                 1.00 
                 82.46 
                 C 
               
               
                 ATOM 
                 615 
                 CE3 
                 TRP 
                 A 
                 74 
                 96.175 
                 21.991 
                 23.163 
                 1.00 
                 81.89 
                 C 
               
               
                 ATOM 
                 616 
                 CZ3 
                 TRP 
                 A 
                 74 
                 97.504 
                 22.080 
                 23.541 
                 1.00 
                 83.00 
                 C 
               
               
                 ATOM 
                 617 
                 CH2 
                 TRP 
                 A 
                 74 
                 98.530 
                 21.649 
                 22.689 
                 1.00 
                 83.09 
                 C 
               
               
                 ATOM 
                 618 
                 CZ2 
                 TRP 
                 A 
                 74 
                 98.262 
                 21.124 
                 21.456 
                 1.00 
                 82.68 
                 C 
               
               
                 ATOM 
                 619 
                 C 
                 TRP 
                 A 
                 74 
                 91.308 
                 20.640 
                 23.015 
                 1.00 
                 78.66 
                 C 
               
               
                 ATOM 
                 620 
                 O 
                 TRP 
                 A 
                 74 
                 90.870 
                 21.787 
                 23.103 
                 1.00 
                 77.18 
                 O 
               
               
                 ATOM 
                 621 
                 N 
                 PHE 
                 A 
                 75 
                 90.576 
                 19.562 
                 23.290 
                 1.00 
                 79.48 
                 N 
               
               
                 ATOM 
                 622 
                 CA 
                 PHE 
                 A 
                 75 
                 89.155 
                 19.645 
                 23.638 
                 1.00 
                 81.86 
                 C 
               
               
                 ATOM 
                 623 
                 CB 
                 PHE 
                 A 
                 75 
                 88.525 
                 18.248 
                 23.675 
                 1.00 
                 81.03 
                 C 
               
               
                 ATOM 
                 624 
                 CG 
                 PHE 
                 A 
                 75 
                 89.025 
                 17.382 
                 24.800 
                 1.00 
                 81.49 
                 C 
               
               
                 ATOM 
                 625 
                 CD1 
                 PHE 
                 A 
                 75 
                 88.464 
                 17.474 
                 26.067 
                 1.00 
                 82.81 
                 C 
               
               
                 ATOM 
                 626 
                 CE1 
                 PHE 
                 A 
                 75 
                 88.920 
                 16.679 
                 27.106 
                 1.00 
                 82.06 
                 C 
               
               
                 ATOM 
                 627 
                 CZ 
                 PHE 
                 A 
                 75 
                 89.945 
                 15.776 
                 26.886 
                 1.00 
                 81.50 
                 C 
               
               
                 ATOM 
                 628 
                 CE2 
                 PHE 
                 A 
                 75 
                 90.513 
                 15.675 
                 25.629 
                 1.00 
                 82.26 
                 C 
               
               
                 ATOM 
                 629 
                 CD2 
                 PHE 
                 A 
                 75 
                 90.052 
                 16.473 
                 24.593 
                 1.00 
                 81.87 
                 C 
               
               
                 ATOM 
                 630 
                 C 
                 PHE 
                 A 
                 75 
                 88.883 
                 20.350 
                 24.966 
                 1.00 
                 84.27 
                 C 
               
               
                 ATOM 
                 631 
                 O 
                 PHE 
                 A 
                 75 
                 87.794 
                 20.879 
                 25.167 
                 1.00 
                 83.13 
                 O 
               
               
                 ATOM 
                 632 
                 N 
                 ASN 
                 A 
                 76 
                 89.857 
                 20.344 
                 25.874 
                 1.00 
                 88.11 
                 N 
               
               
                 ATOM 
                 633 
                 CA 
                 ASN 
                 A 
                 76 
                 89.682 
                 20.985 
                 27.186 
                 1.00 
                 89.63 
                 C 
               
               
                 ATOM 
                 634 
                 CB 
                 ASN 
                 A 
                 76 
                 90.845 
                 20.651 
                 28.129 
                 1.00 
                 92.20 
                 C 
               
               
                 ATOM 
                 635 
                 CG 
                 ASN 
                 A 
                 76 
                 92.193 
                 21.063 
                 27.577 
                 1.00 
                 94.54 
                 C 
               
               
                 ATOM 
                 636 
                 OD1 
                 ASN 
                 A 
                 76 
                 92.288 
                 21.819 
                 26.609 
                 1.00 
                 96.72 
                 O 
               
               
                 ATOM 
                 637 
                 ND2 
                 ASN 
                 A 
                 76 
                 93.249 
                 20.564 
                 28.198 
                 1.00 
                 98.59 
                 N 
               
               
                 ATOM 
                 638 
                 C 
                 ASN 
                 A 
                 76 
                 89.463 
                 22.498 
                 27.114 
                 1.00 
                 88.24 
                 C 
               
               
                 ATOM 
                 639 
                 O 
                 ASN 
                 A 
                 76 
                 88.887 
                 23.084 
                 28.029 
                 1.00 
                 90.63 
                 O 
               
               
                 ATOM 
                 640 
                 N 
                 SER 
                 A 
                 77 
                 89.933 
                 23.123 
                 26.036 
                 1.00 
                 87.91 
                 N 
               
               
                 ATOM 
                 641 
                 CA 
                 SER 
                 A 
                 77 
                 89.700 
                 24.548 
                 25.801 
                 1.00 
                 88.76 
                 C 
               
               
                 ATOM 
                 642 
                 CB 
                 SER 
                 A 
                 77 
                 90.924 
                 25.195 
                 25.151 
                 1.00 
                 87.82 
                 C 
               
               
                 ATOM 
                 643 
                 OG 
                 SER 
                 A 
                 77 
                 91.255 
                 24.559 
                 23.934 
                 1.00 
                 88.97 
                 O 
               
               
                 ATOM 
                 644 
                 C 
                 SER 
                 A 
                 77 
                 88.456 
                 24.775 
                 24.934 
                 1.00 
                 89.89 
                 C 
               
               
                 ATOM 
                 645 
                 O 
                 SER 
                 A 
                 77 
                 88.060 
                 25.916 
                 24.702 
                 1.00 
                 90.07 
                 O 
               
               
                 ATOM 
                 646 
                 N 
                 SER 
                 A 
                 78 
                 87.850 
                 23.689 
                 24.453 
                 1.00 
                 94.92 
                 N 
               
               
                 ATOM 
                 647 
                 CA 
                 SER 
                 A 
                 78 
                 86.629 
                 23.761 
                 23.649 
                 1.00 
                 99.03 
                 C 
               
               
                 ATOM 
                 648 
                 CB 
                 SER 
                 A 
                 78 
                 86.590 
                 22.628 
                 22.623 
                 1.00 
                 99.62 
                 C 
               
               
                 ATOM 
                 649 
                 OG 
                 SER 
                 A 
                 78 
                 86.188 
                 21.405 
                 23.222 
                 1.00 
                 97.38 
                 O 
               
               
                 ATOM 
                 650 
                 C 
                 SER 
                 A 
                 78 
                 85.422 
                 23.637 
                 24.574 
                 1.00 
                 102.60 
                 C 
               
               
                 ATOM 
                 651 
                 O 
                 SER 
                 A 
                 78 
                 85.491 
                 22.969 
                 25.600 
                 1.00 
                 103.92 
                 O 
               
               
                 ATOM 
                 652 
                 N 
                 GLU 
                 A 
                 79 
                 84.313 
                 24.267 
                 24.207 
                 1.00 
                 108.55 
                 N 
               
               
                 ATOM 
                 653 
                 CA 
                 GLU 
                 A 
                 79 
                 83.107 
                 24.256 
                 25.060 
                 1.00 
                 114.49 
                 C 
               
               
                 ATOM 
                 654 
                 CB 
                 GLU 
                 A 
                 79 
                 82.200 
                 25.440 
                 24.691 
                 1.00 
                 123.71 
                 C 
               
               
                 ATOM 
                 655 
                 CG 
                 GLU 
                 A 
                 79 
                 80.904 
                 25.532 
                 25.489 
                 1.00 
                 132.76 
                 C 
               
               
                 ATOM 
                 656 
                 CD 
                 GLU 
                 A 
                 79 
                 80.009 
                 26.677 
                 25.043 
                 1.00 
                 140.84 
                 C 
               
               
                 ATOM 
                 657 
                 OE1 
                 GLU 
                 A 
                 79 
                 80.450 
                 27.508 
                 24.217 
                 1.00 
                 147.37 
                 O 
               
               
                 ATOM 
                 658 
                 OE2 
                 GLU 
                 A 
                 79 
                 78.857 
                 26.748 
                 25.519 
                 1.00 
                 143.38 
                 O 
               
               
                 ATOM 
                 659 
                 C 
                 GLU 
                 A 
                 79 
                 82.293 
                 22.953 
                 25.091 
                 1.00 
                 109.97 
                 C 
               
               
                 ATOM 
                 660 
                 O 
                 GLU 
                 A 
                 79 
                 81.727 
                 22.609 
                 26.129 
                 1.00 
                 106.29 
                 O 
               
               
                 ATOM 
                 661 
                 N 
                 GLY 
                 A 
                 80 
                 82.220 
                 22.242 
                 23.971 
                 1.00 
                 110.25 
                 N 
               
               
                 ATOM 
                 662 
                 CA 
                 GLY 
                 A 
                 80 
                 81.446 
                 20.997 
                 23.891 
                 1.00 
                 107.47 
                 C 
               
               
                 ATOM 
                 663 
                 C 
                 GLY 
                 A 
                 80 
                 81.995 
                 19.802 
                 24.660 
                 1.00 
                 104.12 
                 C 
               
               
                 ATOM 
                 664 
                 O 
                 GLY 
                 A 
                 80 
                 81.264 
                 18.857 
                 24.953 
                 1.00 
                 104.62 
                 O 
               
               
                 ATOM 
                 665 
                 N 
                 GLY 
                 A 
                 81 
                 83.275 
                 19.851 
                 25.012 
                 1.00 
                 100.72 
                 N 
               
               
                 ATOM 
                 666 
                 CA 
                 GLY 
                 A 
                 81 
                 83.952 
                 18.716 
                 25.629 
                 1.00 
                 97.65 
                 C 
               
               
                 ATOM 
                 667 
                 C 
                 GLY 
                 A 
                 81 
                 84.530 
                 17.772 
                 24.592 
                 1.00 
                 93.95 
                 C 
               
               
                 ATOM 
                 668 
                 O 
                 GLY 
                 A 
                 81 
                 84.514 
                 18.060 
                 23.394 
                 1.00 
                 92.80 
                 O 
               
               
                 ATOM 
                 669 
                 N 
                 ASN 
                 A 
                 82 
                 85.027 
                 16.633 
                 25.063 
                 1.00 
                 92.19 
                 N 
               
               
                 ATOM 
                 670 
                 CA 
                 ASN 
                 A 
                 82 
                 85.684 
                 15.651 
                 24.207 
                 1.00 
                 90.58 
                 C 
               
               
                 ATOM 
                 671 
                 CB 
                 ASN 
                 A 
                 82 
                 86.543 
                 14.713 
                 25.058 
                 1.00 
                 90.22 
                 C 
               
               
                 ATOM 
                 672 
                 CG 
                 ASN 
                 A 
                 82 
                 87.370 
                 13.761 
                 24.221 
                 1.00 
                 90.16 
                 C 
               
               
                 ATOM 
                 673 
                 OD1 
                 ASN 
                 A 
                 82 
                 87.340 
                 13.811 
                 22.994 
                 1.00 
                 93.93 
                 O 
               
               
                 ATOM 
                 674 
                 ND2 
                 ASN 
                 A 
                 82 
                 88.116 
                 12.889 
                 24.882 
                 1.00 
                 90.44 
                 N 
               
               
                 ATOM 
                 675 
                 C 
                 ASN 
                 A 
                 82 
                 84.721 
                 14.806 
                 23.376 
                 1.00 
                 91.56 
                 C 
               
               
                 ATOM 
                 676 
                 O 
                 ASN 
                 A 
                 82 
                 83.892 
                 14.076 
                 23.922 
                 1.00 
                 92.50 
                 O 
               
               
                 ATOM 
                 677 
                 N 
                 ILE 
                 A 
                 83 
                 84.850 
                 14.902 
                 22.054 
                 1.00 
                 91.59 
                 N 
               
               
                 ATOM 
                 678 
                 CA 
                 ILE 
                 A 
                 83 
                 84.067 
                 14.083 
                 21.128 
                 1.00 
                 92.28 
                 C 
               
               
                 ATOM 
                 679 
                 CB 
                 ILE 
                 A 
                 83 
                 83.002 
                 14.924 
                 20.383 
                 1.00 
                 92.95 
                 C 
               
               
                 ATOM 
                 680 
                 CG1 
                 ILE 
                 A 
                 83 
                 83.655 
                 15.994 
                 19.494 
                 1.00 
                 93.81 
                 C 
               
               
                 ATOM 
                 681 
                 CD1 
                 ILE 
                 A 
                 83 
                 82.671 
                 16.825 
                 18.698 
                 1.00 
                 94.08 
                 C 
               
               
                 ATOM 
                 682 
                 CG2 
                 ILE 
                 A 
                 83 
                 82.048 
                 15.565 
                 21.378 
                 1.00 
                 93.58 
                 C 
               
               
                 ATOM 
                 683 
                 C 
                 ILE 
                 A 
                 83 
                 84.953 
                 13.371 
                 20.103 
                 1.00 
                 92.93 
                 C 
               
               
                 ATOM 
                 684 
                 O 
                 ILE 
                 A 
                 83 
                 84.443 
                 12.795 
                 19.141 
                 1.00 
                 95.28 
                 O 
               
               
                 ATOM 
                 685 
                 N 
                 GLN 
                 A 
                 84 
                 86.269 
                 13.390 
                 20.316 
                 1.00 
                 91.26 
                 N 
               
               
                 ATOM 
                 686 
                 CA 
                 GLN 
                 A 
                 84 
                 87.202 
                 12.832 
                 19.337 
                 1.00 
                 91.95 
                 C 
               
               
                 ATOM 
                 687 
                 CB 
                 GLN 
                 A 
                 84 
                 88.656 
                 13.183 
                 19.686 
                 1.00 
                 93.42 
                 C 
               
               
                 ATOM 
                 688 
                 CG 
                 GLN 
                 A 
                 84 
                 89.228 
                 12.543 
                 20.940 
                 1.00 
                 92.49 
                 C 
               
               
                 ATOM 
                 689 
                 CD 
                 GLN 
                 A 
                 84 
                 90.513 
                 13.214 
                 21.412 
                 1.00 
                 91.92 
                 C 
               
               
                 ATOM 
                 690 
                 OE1 
                 GLN 
                 A 
                 84 
                 90.641 
                 13.518 
                 22.588 
                 1.00 
                 93.06 
                 O 
               
               
                 ATOM 
                 691 
                 NE2 
                 GLN 
                 A 
                 84 
                 91.453 
                 13.469 
                 20.497 
                 1.00 
                 89.11 
                 N 
               
               
                 ATOM 
                 692 
                 C 
                 GLN 
                 A 
                 84 
                 87.021 
                 11.331 
                 19.159 
                 1.00 
                 88.78 
                 C 
               
               
                 ATOM 
                 693 
                 O 
                 GLN 
                 A 
                 84 
                 86.706 
                 10.617 
                 20.110 
                 1.00 
                 87.28 
                 O 
               
               
                 ATOM 
                 694 
                 N 
                 ASN 
                 A 
                 85 
                 87.207 
                 10.875 
                 17.923 
                 1.00 
                 88.53 
                 N 
               
               
                 ATOM 
                 695 
                 CA 
                 ASN 
                 A 
                 85 
                 86.994 
                 9.478 
                 17.560 
                 1.00 
                 86.85 
                 C 
               
               
                 ATOM 
                 696 
                 CB 
                 ASN 
                 A 
                 85 
                 85.559 
                 9.296 
                 17.050 
                 1.00 
                 88.39 
                 C 
               
               
                 ATOM 
                 697 
                 CG 
                 ASN 
                 A 
                 85 
                 85.231 
                 7.852 
                 16.728 
                 1.00 
                 90.44 
                 C 
               
               
                 ATOM 
                 698 
                 OD1 
                 ASN 
                 A 
                 85 
                 85.629 
                 6.938 
                 17.448 
                 1.00 
                 91.39 
                 O 
               
               
                 ATOM 
                 699 
                 ND2 
                 ASN 
                 A 
                 85 
                 84.495 
                 7.640 
                 15.644 
                 1.00 
                 95.33 
                 N 
               
               
                 ATOM 
                 700 
                 C 
                 ASN 
                 A 
                 85 
                 88.000 
                 9.008 
                 16.507 
                 1.00 
                 82.78 
                 C 
               
               
                 ATOM 
                 701 
                 O 
                 ASN 
                 A 
                 85 
                 87.668 
                 8.860 
                 15.331 
                 1.00 
                 82.04 
                 O 
               
               
                 ATOM 
                 702 
                 N 
                 GLY 
                 A 
                 86 
                 89.235 
                 8.784 
                 16.946 
                 1.00 
                 80.60 
                 N 
               
               
                 ATOM 
                 703 
                 CA 
                 GLY 
                 A 
                 86 
                 90.294 
                 8.289 
                 16.072 
                 1.00 
                 78.14 
                 C 
               
               
                 ATOM 
                 704 
                 C 
                 GLY 
                 A 
                 86 
                 90.655 
                 9.265 
                 14.972 
                 1.00 
                 76.72 
                 C 
               
               
                 ATOM 
                 705 
                 O 
                 GLY 
                 A 
                 86 
                 90.790 
                 10.462 
                 15.217 
                 1.00 
                 78.98 
                 O 
               
               
                 ATOM 
                 706 
                 N 
                 ASN 
                 A 
                 87 
                 90.792 
                 8.751 
                 13.753 
                 1.00 
                 76.52 
                 N 
               
               
                 ATOM 
                 707 
                 CA 
                 ASN 
                 A 
                 87 
                 91.156 
                 9.571 
                 12.591 
                 1.00 
                 76.73 
                 C 
               
               
                 ATOM 
                 708 
                 CB 
                 ASN 
                 A 
                 87 
                 91.836 
                 8.710 
                 11.516 
                 1.00 
                 76.38 
                 C 
               
               
                 ATOM 
                 709 
                 CG 
                 ASN 
                 A 
                 87 
                 93.330 
                 8.566 
                 11.734 
                 1.00 
                 75.91 
                 C 
               
               
                 ATOM 
                 710 
                 OD1 
                 ASN 
                 A 
                 87 
                 94.020 
                 9.537 
                 12.034 
                 1.00 
                 72.57 
                 O 
               
               
                 ATOM 
                 711 
                 ND2 
                 ASN 
                 A 
                 87 
                 93.842 
                 7.354 
                 11.552 
                 1.00 
                 78.45 
                 N 
               
               
                 ATOM 
                 712 
                 C 
                 ASN 
                 A 
                 87 
                 90.006 
                 10.355 
                 11.953 
                 1.00 
                 77.29 
                 C 
               
               
                 ATOM 
                 713 
                 O 
                 ASN 
                 A 
                 87 
                 90.212 
                 11.019 
                 10.940 
                 1.00 
                 78.45 
                 O 
               
               
                 ATOM 
                 714 
                 N 
                 ASP 
                 A 
                 88 
                 88.811 
                 10.293 
                 12.535 
                 1.00 
                 77.80 
                 N 
               
               
                 ATOM 
                 715 
                 CA 
                 ASP 
                 A 
                 88 
                 87.659 
                 11.015 
                 11.994 
                 1.00 
                 79.67 
                 C 
               
               
                 ATOM 
                 716 
                 CB 
                 ASP 
                 A 
                 88 
                 86.369 
                 10.517 
                 12.654 
                 1.00 
                 79.19 
                 C 
               
               
                 ATOM 
                 717 
                 CG 
                 ASP 
                 A 
                 88 
                 85.114 
                 11.001 
                 11.945 
                 1.00 
                 81.31 
                 C 
               
               
                 ATOM 
                 718 
                 OD1 
                 ASP 
                 A 
                 88 
                 85.179 
                 11.989 
                 11.182 
                 1.00 
                 84.32 
                 O 
               
               
                 ATOM 
                 719 
                 OD2 
                 ASP 
                 A 
                 88 
                 84.050 
                 10.382 
                 12.154 
                 1.00 
                 84.65 
                 O 
               
               
                 ATOM 
                 720 
                 C 
                 ASP 
                 A 
                 88 
                 87.826 
                 12.530 
                 12.209 
                 1.00 
                 81.10 
                 C 
               
               
                 ATOM 
                 721 
                 O 
                 ASP 
                 A 
                 88 
                 87.862 
                 12.985 
                 13.354 
                 1.00 
                 85.52 
                 O 
               
               
                 ATOM 
                 722 
                 N 
                 PRO 
                 A 
                 89 
                 87.937 
                 13.311 
                 11.112 
                 1.00 
                 80.28 
                 N 
               
               
                 ATOM 
                 723 
                 CA 
                 PRO 
                 A 
                 89 
                 88.069 
                 14.765 
                 11.244 
                 1.00 
                 80.13 
                 C 
               
               
                 ATOM 
                 724 
                 CB 
                 PRO 
                 A 
                 89 
                 88.398 
                 15.231 
                 9.816 
                 1.00 
                 81.36 
                 C 
               
               
                 ATOM 
                 725 
                 CG 
                 PRO 
                 A 
                 89 
                 88.773 
                 14.005 
                 9.063 
                 1.00 
                 81.57 
                 C 
               
               
                 ATOM 
                 726 
                 CD 
                 PRO 
                 A 
                 89 
                 87.996 
                 12.898 
                 9.700 
                 1.00 
                 81.53 
                 C 
               
               
                 ATOM 
                 727 
                 C 
                 PRO 
                 A 
                 89 
                 86.802 
                 15.462 
                 11.738 
                 1.00 
                 81.61 
                 C 
               
               
                 ATOM 
                 728 
                 O 
                 PRO 
                 A 
                 89 
                 86.882 
                 16.565 
                 12.271 
                 1.00 
                 82.89 
                 O 
               
               
                 ATOM 
                 729 
                 N 
                 CYS 
                 A 
                 90 
                 85.643 
                 14.842 
                 11.545 
                 1.00 
                 83.76 
                 N 
               
               
                 ATOM 
                 730 
                 CA 
                 CYS 
                 A 
                 90 
                 84.397 
                 15.408 
                 12.052 
                 1.00 
                 87.12 
                 C 
               
               
                 ATOM 
                 731 
                 CB 
                 CYS 
                 A 
                 90 
                 83.756 
                 16.336 
                 11.019 
                 1.00 
                 89.21 
                 C 
               
               
                 ATOM 
                 732 
                 SG 
                 CYS 
                 A 
                 90 
                 82.536 
                 17.452 
                 11.749 
                 1.00 
                 97.73 
                 S 
               
               
                 ATOM 
                 733 
                 C 
                 CYS 
                 A 
                 90 
                 83.441 
                 14.291 
                 12.475 
                 1.00 
                 87.04 
                 C 
               
               
                 ATOM 
                 734 
                 O 
                 CYS 
                 A 
                 90 
                 82.627 
                 13.831 
                 11.676 
                 1.00 
                 88.42 
                 O 
               
               
                 ATOM 
                 735 
                 N 
                 PRO 
                 A 
                 91 
                 83.560 
                 13.834 
                 13.736 
                 1.00 
                 88.68 
                 N 
               
               
                 ATOM 
                 736 
                 CA 
                 PRO 
                 A 
                 91 
                 82.711 
                 12.766 
                 14.265 
                 1.00 
                 87.95 
                 C 
               
               
                 ATOM 
                 737 
                 CB 
                 PRO 
                 A 
                 91 
                 83.210 
                 12.595 
                 15.706 
                 1.00 
                 88.48 
                 C 
               
               
                 ATOM 
                 738 
                 CG 
                 PRO 
                 A 
                 91 
                 84.600 
                 13.125 
                 15.697 
                 1.00 
                 89.41 
                 C 
               
               
                 ATOM 
                 739 
                 CD 
                 PRO 
                 A 
                 91 
                 84.582 
                 14.252 
                 14.712 
                 1.00 
                 89.53 
                 C 
               
               
                 ATOM 
                 740 
                 C 
                 PRO 
                 A 
                 91 
                 81.231 
                 13.133 
                 14.254 
                 1.00 
                 87.89 
                 C 
               
               
                 ATOM 
                 741 
                 O 
                 PRO 
                 A 
                 91 
                 80.864 
                 14.231 
                 14.670 
                 1.00 
                 88.66 
                 O 
               
               
                 ATOM 
                 742 
                 N 
                 GLY 
                 A 
                 92 
                 80.400 
                 12.216 
                 13.768 
                 1.00 
                 88.83 
                 N 
               
               
                 ATOM 
                 743 
                 CA 
                 GLY 
                 A 
                 92 
                 78.956 
                 12.427 
                 13.711 
                 1.00 
                 88.73 
                 C 
               
               
                 ATOM 
                 744 
                 C 
                 GLY 
                 A 
                 92 
                 78.455 
                 13.014 
                 12.404 
                 1.00 
                 87.94 
                 C 
               
               
                 ATOM 
                 745 
                 O 
                 GLY 
                 A 
                 92 
                 77.247 
                 13.115 
                 12.200 
                 1.00 
                 92.01 
                 O 
               
               
                 ATOM 
                 746 
                 N 
                 SER 
                 A 
                 93 
                 79.372 
                 13.401 
                 11.519 
                 1.00 
                 85.11 
                 N 
               
               
                 ATOM 
                 747 
                 CA 
                 SER 
                 A 
                 93 
                 79.009 
                 13.950 
                 10.211 
                 1.00 
                 83.68 
                 C 
               
               
                 ATOM 
                 748 
                 CB 
                 SER 
                 A 
                 93 
                 79.288 
                 15.455 
                 10.156 
                 1.00 
                 83.96 
                 C 
               
               
                 ATOM 
                 749 
                 OG 
                 SER 
                 A 
                 93 
                 80.668 
                 15.729 
                 10.309 
                 1.00 
                 86.87 
                 O 
               
               
                 ATOM 
                 750 
                 C 
                 SER 
                 A 
                 93 
                 79.765 
                 13.203 
                 9.102 
                 1.00 
                 81.71 
                 C 
               
               
                 ATOM 
                 751 
                 O 
                 SER 
                 A 
                 93 
                 80.841 
                 12.653 
                 9.346 
                 1.00 
                 79.60 
                 O 
               
               
                 ATOM 
                 752 
                 N 
                 PRO 
                 A 
                 94 
                 79.195 
                 13.171 
                 7.881 
                 1.00 
                 81.27 
                 N 
               
               
                 ATOM 
                 753 
                 CA 
                 PRO 
                 A 
                 94 
                 79.796 
                 12.420 
                 6.781 
                 1.00 
                 79.29 
                 C 
               
               
                 ATOM 
                 754 
                 CB 
                 PRO 
                 A 
                 94 
                 78.625 
                 12.248 
                 5.816 
                 1.00 
                 81.13 
                 C 
               
               
                 ATOM 
                 755 
                 CG 
                 PRO 
                 A 
                 94 
                 77.800 
                 13.467 
                 6.022 
                 1.00 
                 80.76 
                 C 
               
               
                 ATOM 
                 756 
                 CD 
                 PRO 
                 A 
                 94 
                 77.957 
                 13.858 
                 7.462 
                 1.00 
                 80.51 
                 C 
               
               
                 ATOM 
                 757 
                 C 
                 PRO 
                 A 
                 94 
                 80.948 
                 13.170 
                 6.107 
                 1.00 
                 78.51 
                 C 
               
               
                 ATOM 
                 758 
                 O 
                 PRO 
                 A 
                 94 
                 81.217 
                 14.320 
                 6.464 
                 1.00 
                 77.25 
                 O 
               
               
                 ATOM 
                 759 
                 N 
                 PRO 
                 A 
                 95 
                 81.628 
                 12.527 
                 5.134 
                 1.00 
                 76.99 
                 N 
               
               
                 ATOM 
                 760 
                 CA 
                 PRO 
                 A 
                 95 
                 82.752 
                 13.168 
                 4.438 
                 1.00 
                 75.51 
                 C 
               
               
                 ATOM 
                 761 
                 CB 
                 PRO 
                 A 
                 95 
                 83.280 
                 12.063 
                 3.515 
                 1.00 
                 74.85 
                 C 
               
               
                 ATOM 
                 762 
                 CG 
                 PRO 
                 A 
                 95 
                 82.794 
                 10.793 
                 4.113 
                 1.00 
                 76.11 
                 C 
               
               
                 ATOM 
                 763 
                 CD 
                 PRO 
                 A 
                 95 
                 81.460 
                 11.127 
                 4.709 
                 1.00 
                 76.90 
                 C 
               
               
                 ATOM 
                 764 
                 C 
                 PRO 
                 A 
                 95 
                 82.383 
                 14.411 
                 3.622 
                 1.00 
                 76.85 
                 C 
               
               
                 ATOM 
                 765 
                 O 
                 PRO 
                 A 
                 95 
                 83.273 
                 15.177 
                 3.255 
                 1.00 
                 73.77 
                 O 
               
               
                 ATOM 
                 766 
                 N 
                 SER 
                 A 
                 96 
                 81.094 
                 14.606 
                 3.337 
                 1.00 
                 79.96 
                 N 
               
               
                 ATOM 
                 767 
                 CA 
                 SER 
                 A 
                 96 
                 80.635 
                 15.806 
                 2.632 
                 1.00 
                 81.01 
                 C 
               
               
                 ATOM 
                 768 
                 CB 
                 SER 
                 A 
                 96 
                 79.130 
                 15.742 
                 2.356 
                 1.00 
                 82.03 
                 C 
               
               
                 ATOM 
                 769 
                 OG 
                 SER 
                 A 
                 96 
                 78.380 
                 15.812 
                 3.556 
                 1.00 
                 81.00 
                 O 
               
               
                 ATOM 
                 770 
                 C 
                 SER 
                 A 
                 96 
                 80.958 
                 17.063 
                 3.436 
                 1.00 
                 81.78 
                 C 
               
               
                 ATOM 
                 771 
                 O 
                 SER 
                 A 
                 96 
                 81.075 
                 18.153 
                 2.876 
                 1.00 
                 82.50 
                 O 
               
               
                 ATOM 
                 772 
                 N 
                 GLU 
                 A 
                 97 
                 81.095 
                 16.898 
                 4.751 
                 1.00 
                 84.85 
                 N 
               
               
                 ATOM 
                 773 
                 CA 
                 GLU 
                 A 
                 97 
                 81.482 
                 17.987 
                 5.638 
                 1.00 
                 85.15 
                 C 
               
               
                 ATOM 
                 774 
                 CB 
                 GLU 
                 A 
                 97 
                 81.290 
                 17.571 
                 7.102 
                 1.00 
                 87.89 
                 C 
               
               
                 ATOM 
                 775 
                 CG 
                 GLU 
                 A 
                 97 
                 81.230 
                 18.728 
                 8.093 
                 1.00 
                 89.90 
                 C 
               
               
                 ATOM 
                 776 
                 CD 
                 GLU 
                 A 
                 97 
                 82.591 
                 19.298 
                 8.462 
                 1.00 
                 90.87 
                 C 
               
               
                 ATOM 
                 777 
                 OE1 
                 GLU 
                 A 
                 97 
                 82.633 
                 20.470 
                 8.886 
                 1.00 
                 90.84 
                 O 
               
               
                 ATOM 
                 778 
                 OE2 
                 GLU 
                 A 
                 97 
                 83.615 
                 18.586 
                 8.340 
                 1.00 
                 90.58 
                 O 
               
               
                 ATOM 
                 779 
                 C 
                 GLU 
                 A 
                 97 
                 82.932 
                 18.407 
                 5.363 
                 1.00 
                 82.63 
                 C 
               
               
                 ATOM 
                 780 
                 O 
                 GLU 
                 A 
                 97 
                 83.256 
                 19.591 
                 5.449 
                 1.00 
                 80.59 
                 O 
               
               
                 ATOM 
                 781 
                 N 
                 TYR 
                 A 
                 98 
                 83.795 
                 17.451 
                 5.010 
                 1.00 
                 81.53 
                 N 
               
               
                 ATOM 
                 782 
                 CA 
                 TYR 
                 A 
                 98 
                 85.179 
                 17.784 
                 4.653 
                 1.00 
                 79.61 
                 C 
               
               
                 ATOM 
                 783 
                 CB 
                 TYR 
                 A 
                 98 
                 86.205 
                 16.673 
                 4.983 
                 1.00 
                 79.95 
                 C 
               
               
                 ATOM 
                 784 
                 CG 
                 TYR 
                 A 
                 98 
                 85.804 
                 15.496 
                 5.847 
                 1.00 
                 80.21 
                 C 
               
               
                 ATOM 
                 785 
                 CD1 
                 TYR 
                 A 
                 98 
                 85.165 
                 15.671 
                 7.065 
                 1.00 
                 83.17 
                 C 
               
               
                 ATOM 
                 786 
                 CE1 
                 TYR 
                 A 
                 98 
                 84.821 
                 14.580 
                 7.851 
                 1.00 
                 86.71 
                 C 
               
               
                 ATOM 
                 787 
                 CZ 
                 TYR 
                 A 
                 98 
                 85.150 
                 13.294 
                 7.436 
                 1.00 
                 85.74 
                 C 
               
               
                 ATOM 
                 788 
                 OH 
                 TYR 
                 A 
                 98 
                 84.815 
                 12.204 
                 8.217 
                 1.00 
                 82.99 
                 O 
               
               
                 ATOM 
                 789 
                 CE2 
                 TYR 
                 A 
                 98 
                 85.816 
                 13.102 
                 6.243 
                 1.00 
                 81.75 
                 C 
               
               
                 ATOM 
                 790 
                 CD2 
                 TYR 
                 A 
                 98 
                 86.147 
                 14.197 
                 5.464 
                 1.00 
                 79.31 
                 C 
               
               
                 ATOM 
                 791 
                 C 
                 TYR 
                 A 
                 98 
                 85.281 
                 18.111 
                 3.148 
                 1.00 
                 78.58 
                 C 
               
               
                 ATOM 
                 792 
                 O 
                 TYR 
                 A 
                 98 
                 86.383 
                 18.165 
                 2.602 
                 1.00 
                 75.58 
                 O 
               
               
                 ATOM 
                 793 
                 N 
                 HIS 
                 A 
                 99 
                 84.138 
                 18.308 
                 2.488 
                 1.00 
                 78.17 
                 N 
               
               
                 ATOM 
                 794 
                 CA 
                 HIS 
                 A 
                 99 
                 84.070 
                 18.625 
                 1.056 
                 1.00 
                 78.49 
                 C 
               
               
                 ATOM 
                 795 
                 CB 
                 HIS 
                 A 
                 99 
                 84.615 
                 20.029 
                 0.775 
                 1.00 
                 80.65 
                 C 
               
               
                 ATOM 
                 796 
                 CG 
                 HIS 
                 A 
                 99 
                 83.839 
                 21.122 
                 1.438 
                 1.00 
                 84.17 
                 C 
               
               
                 ATOM 
                 797 
                 ND1 
                 HIS 
                 A 
                 99 
                 82.534 
                 21.414 
                 1.104 
                 1.00 
                 86.58 
                 N 
               
               
                 ATOM 
                 798 
                 CE1 
                 HIS 
                 A 
                 99 
                 82.108 
                 22.423 
                 1.841 
                 1.00 
                 87.71 
                 C 
               
               
                 ATOM 
                 799 
                 NE2 
                 HIS 
                 A 
                 99 
                 83.091 
                 22.802 
                 2.637 
                 1.00 
                 87.96 
                 N 
               
               
                 ATOM 
                 800 
                 CD2 
                 HIS 
                 A 
                 99 
                 84.187 
                 22.006 
                 2.402 
                 1.00 
                 85.49 
                 C 
               
               
                 ATOM 
                 801 
                 C 
                 HIS 
                 A 
                 99 
                 84.760 
                 17.591 
                 0.157 
                 1.00 
                 77.06 
                 C 
               
               
                 ATOM 
                 802 
                 O 
                 HIS 
                 A 
                 99 
                 85.602 
                 17.933 
                 −0.678 
                 1.00 
                 75.08 
                 O 
               
               
                 ATOM 
                 803 
                 N 
                 THR 
                 A 
                 100 
                 84.385 
                 16.328 
                 0.333 
                 1.00 
                 76.26 
                 N 
               
               
                 ATOM 
                 804 
                 CA 
                 THR 
                 A 
                 100 
                 84.905 
                 15.243 
                 −0.494 
                 1.00 
                 75.33 
                 C 
               
               
                 ATOM 
                 805 
                 CB 
                 THR 
                 A 
                 100 
                 86.259 
                 14.719 
                 0.026 
                 1.00 
                 75.69 
                 C 
               
               
                 ATOM 
                 806 
                 OG1 
                 THR 
                 A 
                 100 
                 86.691 
                 13.618 
                 −0.781 
                 1.00 
                 73.34 
                 O 
               
               
                 ATOM 
                 807 
                 CG2 
                 THR 
                 A 
                 100 
                 86.161 
                 14.268 
                 1.487 
                 1.00 
                 76.67 
                 C 
               
               
                 ATOM 
                 808 
                 C 
                 THR 
                 A 
                 100 
                 83.904 
                 14.094 
                 −0.565 
                 1.00 
                 77.28 
                 C 
               
               
                 ATOM 
                 809 
                 O 
                 THR 
                 A 
                 100 
                 83.156 
                 13.852 
                 0.381 
                 1.00 
                 78.28 
                 O 
               
               
                 ATOM 
                 810 
                 N 
                 THR 
                 A 
                 101 
                 83.893 
                 13.401 
                 −1.700 
                 1.00 
                 79.81 
                 N 
               
               
                 ATOM 
                 811 
                 CA 
                 THR 
                 A 
                 101 
                 83.006 
                 12.257 
                 −1.908 
                 1.00 
                 78.80 
                 C 
               
               
                 ATOM 
                 812 
                 CB 
                 THR 
                 A 
                 101 
                 82.726 
                 12.026 
                 −3.405 
                 1.00 
                 78.80 
                 C 
               
               
                 ATOM 
                 813 
                 OG1 
                 THR 
                 A 
                 101 
                 83.949 
                 11.727 
                 −4.091 
                 1.00 
                 80.62 
                 O 
               
               
                 ATOM 
                 814 
                 CG2 
                 THR 
                 A 
                 101 
                 82.095 
                 13.259 
                 −4.025 
                 1.00 
                 78.50 
                 C 
               
               
                 ATOM 
                 815 
                 C 
                 THR 
                 A 
                 101 
                 83.630 
                 10.999 
                 −1.314 
                 1.00 
                 77.63 
                 C 
               
               
                 ATOM 
                 816 
                 O 
                 THR 
                 A 
                 101 
                 82.924 
                 10.127 
                 −0.809 
                 1.00 
                 79.35 
                 O 
               
               
                 ATOM 
                 817 
                 N 
                 GLY 
                 A 
                 102 
                 84.957 
                 10.912 
                 −1.389 
                 1.00 
                 74.75 
                 N 
               
               
                 ATOM 
                 818 
                 CA 
                 GLY 
                 A 
                 102 
                 85.700 
                 9.780 
                 −0.843 
                 1.00 
                 73.71 
                 C 
               
               
                 ATOM 
                 819 
                 C 
                 GLY 
                 A 
                 102 
                 87.185 
                 10.075 
                 −0.760 
                 1.00 
                 72.34 
                 C 
               
               
                 ATOM 
                 820 
                 O 
                 GLY 
                 A 
                 102 
                 87.616 
                 11.198 
                 −1.013 
                 1.00 
                 71.11 
                 O 
               
               
                 ATOM 
                 821 
                 N 
                 ILE 
                 A 
                 103 
                 87.971 
                 9.062 
                 −0.411 
                 1.00 
                 73.72 
                 N 
               
               
                 ATOM 
                 822 
                 CA 
                 ILE 
                 A 
                 103 
                 89.422 
                 9.218 
                 −0.295 
                 1.00 
                 77.88 
                 C 
               
               
                 ATOM 
                 823 
                 CB 
                 ILE 
                 A 
                 103 
                 90.077 
                 7.954 
                 0.313 
                 1.00 
                 78.60 
                 C 
               
               
                 ATOM 
                 824 
                 CG1 
                 ILE 
                 A 
                 103 
                 91.526 
                 8.238 
                 0.723 
                 1.00 
                 79.37 
                 C 
               
               
                 ATOM 
                 825 
                 CD1 
                 ILE 
                 A 
                 103 
                 92.155 
                 7.125 
                 1.531 
                 1.00 
                 81.18 
                 C 
               
               
                 ATOM 
                 826 
                 CG2 
                 ILE 
                 A 
                 103 
                 90.005 
                 6.774 
                 −0.650 
                 1.00 
                 79.39 
                 C 
               
               
                 ATOM 
                 827 
                 C 
                 ILE 
                 A 
                 103 
                 90.080 
                 9.560 
                 −1.638 
                 1.00 
                 81.78 
                 C 
               
               
                 ATOM 
                 828 
                 O 
                 ILE 
                 A 
                 103 
                 91.135 
                 10.193 
                 −1.677 
                 1.00 
                 83.03 
                 O 
               
               
                 ATOM 
                 829 
                 N 
                 ASP 
                 A 
                 104 
                 89.454 
                 9.131 
                 −2.730 
                 1.00 
                 88.15 
                 N 
               
               
                 ATOM 
                 830 
                 CA 
                 ASP 
                 A 
                 104 
                 89.956 
                 9.401 
                 −4.083 
                 1.00 
                 91.83 
                 C 
               
               
                 ATOM 
                 831 
                 CB 
                 ASP 
                 A 
                 104 
                 89.357 
                 8.399 
                 −5.089 
                 1.00 
                 98.41 
                 C 
               
               
                 ATOM 
                 832 
                 CG 
                 ASP 
                 A 
                 104 
                 87.828 
                 8.292 
                 −4.998 
                 1.00 
                 106.90 
                 C 
               
               
                 ATOM 
                 833 
                 OD1 
                 ASP 
                 A 
                 104 
                 87.191 
                 9.093 
                 −4.276 
                 1.00 
                 108.74 
                 O 
               
               
                 ATOM 
                 834 
                 OD2 
                 ASP 
                 A 
                 104 
                 87.263 
                 7.390 
                 −5.653 
                 1.00 
                 115.22 
                 O 
               
               
                 ATOM 
                 835 
                 C 
                 ASP 
                 A 
                 104 
                 89.704 
                 10.844 
                 −4.547 
                 1.00 
                 87.09 
                 C 
               
               
                 ATOM 
                 836 
                 O 
                 ASP 
                 A 
                 104 
                 90.380 
                 11.332 
                 −5.454 
                 1.00 
                 85.40 
                 O 
               
               
                 ATOM 
                 837 
                 N 
                 ASP 
                 A 
                 105 
                 88.747 
                 11.520 
                 −3.913 
                 1.00 
                 84.52 
                 N 
               
               
                 ATOM 
                 838 
                 CA 
                 ASP 
                 A 
                 105 
                 88.347 
                 12.878 
                 −4.300 
                 1.00 
                 83.78 
                 C 
               
               
                 ATOM 
                 839 
                 CB 
                 ASP 
                 A 
                 105 
                 86.818 
                 12.984 
                 −4.220 
                 1.00 
                 83.39 
                 C 
               
               
                 ATOM 
                 840 
                 CG 
                 ASP 
                 A 
                 105 
                 86.278 
                 14.287 
                 −4.782 
                 1.00 
                 83.83 
                 C 
               
               
                 ATOM 
                 841 
                 OD1 
                 ASP 
                 A 
                 105 
                 86.840 
                 14.809 
                 −5.772 
                 1.00 
                 84.71 
                 O 
               
               
                 ATOM 
                 842 
                 OD2 
                 ASP 
                 A 
                 105 
                 85.271 
                 14.779 
                 −4.231 
                 1.00 
                 83.05 
                 O 
               
               
                 ATOM 
                 843 
                 C 
                 ASP 
                 A 
                 105 
                 89.006 
                 13.990 
                 −3.462 
                 1.00 
                 82.38 
                 C 
               
               
                 ATOM 
                 844 
                 O 
                 ASP 
                 A 
                 105 
                 88.697 
                 15.169 
                 −3.637 
                 1.00 
                 84.48 
                 O 
               
               
                 ATOM 
                 845 
                 N 
                 VAL 
                 A 
                 106 
                 89.915 
                 13.623 
                 −2.562 
                 1.00 
                 80.21 
                 N 
               
               
                 ATOM 
                 846 
                 CA 
                 VAL 
                 A 
                 106 
                 90.636 
                 14.616 
                 −1.758 
                 1.00 
                 76.79 
                 C 
               
               
                 ATOM 
                 847 
                 CB 
                 VAL 
                 A 
                 106 
                 91.240 
                 14.007 
                 −0.473 
                 1.00 
                 76.30 
                 C 
               
               
                 ATOM 
                 848 
                 CG1 
                 VAL 
                 A 
                 106 
                 90.152 
                 13.342 
                 0.361 
                 1.00 
                 75.86 
                 C 
               
               
                 ATOM 
                 849 
                 CG2 
                 VAL 
                 A 
                 106 
                 92.364 
                 13.028 
                 −0.792 
                 1.00 
                 75.64 
                 C 
               
               
                 ATOM 
                 850 
                 C 
                 VAL 
                 A 
                 106 
                 91.732 
                 15.252 
                 −2.613 
                 1.00 
                 77.16 
                 C 
               
               
                 ATOM 
                 851 
                 O 
                 VAL 
                 A 
                 106 
                 92.360 
                 14.571 
                 −3.425 
                 1.00 
                 78.52 
                 O 
               
               
                 ATOM 
                 852 
                 N 
                 LYS 
                 A 
                 107 
                 91.964 
                 16.550 
                 −2.423 
                 1.00 
                 76.96 
                 N 
               
               
                 ATOM 
                 853 
                 CA 
                 LYS 
                 A 
                 107 
                 92.907 
                 17.302 
                 −3.262 
                 1.00 
                 76.64 
                 C 
               
               
                 ATOM 
                 854 
                 CB 
                 LYS 
                 A 
                 107 
                 92.202 
                 18.528 
                 −3.844 
                 1.00 
                 78.36 
                 C 
               
               
                 ATOM 
                 855 
                 CG 
                 LYS 
                 A 
                 107 
                 90.971 
                 18.201 
                 −4.675 
                 1.00 
                 80.98 
                 C 
               
               
                 ATOM 
                 856 
                 CD 
                 LYS 
                 A 
                 107 
                 91.330 
                 17.445 
                 −5.943 
                 1.00 
                 83.14 
                 C 
               
               
                 ATOM 
                 857 
                 CE 
                 LYS 
                 A 
                 107 
                 90.093 
                 17.097 
                 −6.748 
                 1.00 
                 85.25 
                 C 
               
               
                 ATOM 
                 858 
                 NZ 
                 LYS 
                 A 
                 107 
                 90.459 
                 16.404 
                 −8.012 
                 1.00 
                 89.06 
                 N 
               
               
                 ATOM 
                 859 
                 C 
                 LYS 
                 A 
                 107 
                 94.197 
                 17.739 
                 −2.568 
                 1.00 
                 75.69 
                 C 
               
               
                 ATOM 
                 860 
                 O 
                 LYS 
                 A 
                 107 
                 95.007 
                 18.443 
                 −3.166 
                 1.00 
                 76.63 
                 O 
               
               
                 ATOM 
                 861 
                 N 
                 GLY 
                 A 
                 108 
                 94.386 
                 17.345 
                 −1.313 
                 1.00 
                 75.76 
                 N 
               
               
                 ATOM 
                 862 
                 CA 
                 GLY 
                 A 
                 108 
                 95.621 
                 17.655 
                 −0.597 
                 1.00 
                 74.81 
                 C 
               
               
                 ATOM 
                 863 
                 C 
                 GLY 
                 A 
                 108 
                 95.705 
                 19.048 
                 0.000 
                 1.00 
                 74.07 
                 C 
               
               
                 ATOM 
                 864 
                 O 
                 GLY 
                 A 
                 108 
                 95.023 
                 19.975 
                 −0.442 
                 1.00 
                 74.11 
                 O 
               
               
                 ATOM 
                 865 
                 N 
                 CYS 
                 A 
                 109 
                 96.561 
                 19.179 
                 1.012 
                 1.00 
                 73.65 
                 N 
               
               
                 ATOM 
                 866 
                 CA 
                 CYS 
                 A 
                 109 
                 96.774 
                 20.438 
                 1.719 
                 1.00 
                 74.38 
                 C 
               
               
                 ATOM 
                 867 
                 CB 
                 CYS 
                 A 
                 109 
                 95.952 
                 20.472 
                 3.003 
                 1.00 
                 77.23 
                 C 
               
               
                 ATOM 
                 868 
                 SG 
                 CYS 
                 A 
                 109 
                 96.511 
                 19.304 
                 4.250 
                 1.00 
                 86.71 
                 S 
               
               
                 ATOM 
                 869 
                 C 
                 CYS 
                 A 
                 109 
                 98.258 
                 20.590 
                 2.034 
                 1.00 
                 70.37 
                 C 
               
               
                 ATOM 
                 870 
                 O 
                 CYS 
                 A 
                 109 
                 99.021 
                 19.636 
                 1.884 
                 1.00 
                 70.18 
                 O 
               
               
                 ATOM 
                 871 
                 N 
                 ALA 
                 A 
                 110 
                 98.661 
                 21.774 
                 2.492 
                 1.00 
                 68.05 
                 N 
               
               
                 ATOM 
                 872 
                 CA 
                 ALA 
                 A 
                 110 
                 100.080 
                 22.073 
                 2.693 
                 1.00 
                 67.71 
                 C 
               
               
                 ATOM 
                 873 
                 CB 
                 ALA 
                 A 
                 110 
                 100.606 
                 22.832 
                 1.484 
                 1.00 
                 66.87 
                 C 
               
               
                 ATOM 
                 874 
                 C 
                 ALA 
                 A 
                 110 
                 100.396 
                 22.864 
                 3.960 
                 1.00 
                 67.08 
                 C 
               
               
                 ATOM 
                 875 
                 O 
                 ALA 
                 A 
                 110 
                 99.507 
                 23.404 
                 4.615 
                 1.00 
                 65.06 
                 O 
               
               
                 ATOM 
                 876 
                 N 
                 MET 
                 A 
                 111 
                 101.687 
                 22.911 
                 4.283 
                 1.00 
                 66.62 
                 N 
               
               
                 ATOM 
                 877 
                 CA 
                 MET 
                 A 
                 111 
                 102.214 
                 23.716 
                 5.376 
                 1.00 
                 68.59 
                 C 
               
               
                 ATOM 
                 878 
                 CB 
                 MET 
                 A 
                 111 
                 102.953 
                 22.855 
                 6.408 
                 1.00 
                 69.75 
                 C 
               
               
                 ATOM 
                 879 
                 CG 
                 MET 
                 A 
                 111 
                 102.147 
                 21.746 
                 7.071 
                 1.00 
                 71.01 
                 C 
               
               
                 ATOM 
                 880 
                 SD 
                 MET 
                 A 
                 111 
                 100.703 
                 22.240 
                 8.040 
                 1.00 
                 71.63 
                 S 
               
               
                 ATOM 
                 881 
                 CE 
                 MET 
                 A 
                 111 
                 101.331 
                 23.608 
                 8.969 
                 1.00 
                 71.26 
                 C 
               
               
                 ATOM 
                 882 
                 C 
                 MET 
                 A 
                 111 
                 103.216 
                 24.694 
                 4.768 
                 1.00 
                 70.65 
                 C 
               
               
                 ATOM 
                 883 
                 O 
                 MET 
                 A 
                 111 
                 104.177 
                 24.273 
                 4.118 
                 1.00 
                 69.63 
                 O 
               
               
                 ATOM 
                 884 
                 N 
                 ALA 
                 A 
                 112 
                 102.993 
                 25.989 
                 4.972 
                 1.00 
                 72.73 
                 N 
               
               
                 ATOM 
                 885 
                 CA 
                 ALA 
                 A 
                 112 
                 103.926 
                 27.013 
                 4.511 
                 1.00 
                 73.22 
                 C 
               
               
                 ATOM 
                 886 
                 CB 
                 ALA 
                 A 
                 112 
                 103.182 
                 28.138 
                 3.816 
                 1.00 
                 74.60 
                 C 
               
               
                 ATOM 
                 887 
                 C 
                 ALA 
                 A 
                 112 
                 104.715 
                 27.550 
                 5.699 
                 1.00 
                 75.00 
                 C 
               
               
                 ATOM 
                 888 
                 O 
                 ALA 
                 A 
                 112 
                 104.319 
                 27.354 
                 6.849 
                 1.00 
                 74.54 
                 O 
               
               
                 ATOM 
                 889 
                 N 
                 ILE 
                 A 
                 113 
                 105.829 
                 28.223 
                 5.417 
                 1.00 
                 75.76 
                 N 
               
               
                 ATOM 
                 890 
                 CA 
                 ILE 
                 A 
                 113 
                 106.684 
                 28.781 
                 6.467 
                 1.00 
                 75.57 
                 C 
               
               
                 ATOM 
                 891 
                 CB 
                 ILE 
                 A 
                 113 
                 107.799 
                 27.787 
                 6.871 
                 1.00 
                 74.30 
                 C 
               
               
                 ATOM 
                 892 
                 CG1 
                 ILE 
                 A 
                 113 
                 108.525 
                 28.264 
                 8.132 
                 1.00 
                 72.52 
                 C 
               
               
                 ATOM 
                 893 
                 CD1 
                 ILE 
                 A 
                 113 
                 109.418 
                 27.209 
                 8.747 
                 1.00 
                 71.73 
                 C 
               
               
                 ATOM 
                 894 
                 CG2 
                 ILE 
                 A 
                 113 
                 108.787 
                 27.567 
                 5.729 
                 1.00 
                 74.42 
                 C 
               
               
                 ATOM 
                 895 
                 C 
                 ILE 
                 A 
                 113 
                 107.318 
                 30.108 
                 6.057 
                 1.00 
                 78.06 
                 C 
               
               
                 ATOM 
                 896 
                 O 
                 ILE 
                 A 
                 113 
                 107.704 
                 30.299 
                 4.903 
                 1.00 
                 78.43 
                 O 
               
               
                 ATOM 
                 897 
                 N 
                 ALA 
                 A 
                 114 
                 107.418 
                 31.017 
                 7.023 
                 1.00 
                 81.36 
                 N 
               
               
                 ATOM 
                 898 
                 CA 
                 ALA 
                 A 
                 114 
                 108.054 
                 32.312 
                 6.827 
                 1.00 
                 82.37 
                 C 
               
               
                 ATOM 
                 899 
                 CB 
                 ALA 
                 A 
                 114 
                 107.010 
                 33.411 
                 6.755 
                 1.00 
                 82.04 
                 C 
               
               
                 ATOM 
                 900 
                 C 
                 ALA 
                 A 
                 114 
                 109.006 
                 32.554 
                 7.992 
                 1.00 
                 84.16 
                 C 
               
               
                 ATOM 
                 901 
                 O 
                 ALA 
                 A 
                 114 
                 108.574 
                 32.630 
                 9.144 
                 1.00 
                 85.37 
                 O 
               
               
                 ATOM 
                 902 
                 N 
                 TYR 
                 A 
                 115 
                 110.297 
                 32.668 
                 7.688 
                 1.00 
                 84.64 
                 N 
               
               
                 ATOM 
                 903 
                 CA 
                 TYR 
                 A 
                 115 
                 111.326 
                 32.873 
                 8.709 
                 1.00 
                 84.66 
                 C 
               
               
                 ATOM 
                 904 
                 CB 
                 TYR 
                 A 
                 115 
                 112.710 
                 32.503 
                 8.165 
                 1.00 
                 82.76 
                 C 
               
               
                 ATOM 
                 905 
                 CG 
                 TYR 
                 A 
                 115 
                 112.967 
                 31.012 
                 8.120 
                 1.00 
                 81.09 
                 C 
               
               
                 ATOM 
                 906 
                 CD1 
                 TYR 
                 A 
                 115 
                 114.000 
                 30.445 
                 8.856 
                 1.00 
                 80.03 
                 C 
               
               
                 ATOM 
                 907 
                 CE1 
                 TYR 
                 A 
                 115 
                 114.239 
                 29.082 
                 8.820 
                 1.00 
                 79.47 
                 C 
               
               
                 ATOM 
                 908 
                 CZ 
                 TYR 
                 A 
                 115 
                 113.434 
                 28.265 
                 8.053 
                 1.00 
                 77.13 
                 C 
               
               
                 ATOM 
                 909 
                 OH 
                 TYR 
                 A 
                 115 
                 113.668 
                 26.915 
                 8.019 
                 1.00 
                 73.14 
                 O 
               
               
                 ATOM 
                 910 
                 CE2 
                 TYR 
                 A 
                 115 
                 112.398 
                 28.800 
                 7.319 
                 1.00 
                 79.12 
                 C 
               
               
                 ATOM 
                 911 
                 CD2 
                 TYR 
                 A 
                 115 
                 112.167 
                 30.165 
                 7.358 
                 1.00 
                 81.10 
                 C 
               
               
                 ATOM 
                 912 
                 C 
                 TYR 
                 A 
                 115 
                 111.304 
                 34.313 
                 9.219 
                 1.00 
                 86.07 
                 C 
               
               
                 ATOM 
                 913 
                 O 
                 TYR 
                 A 
                 115 
                 112.121 
                 35.147 
                 8.821 
                 1.00 
                 85.81 
                 O 
               
               
                 ATOM 
                 914 
                 N 
                 GLU 
                 A 
                 116 
                 110.346 
                 34.586 
                 10.100 
                 1.00 
                 87.27 
                 N 
               
               
                 ATOM 
                 915 
                 CA 
                 GLU 
                 A 
                 116 
                 110.166 
                 35.905 
                 10.685 
                 1.00 
                 91.13 
                 C 
               
               
                 ATOM 
                 916 
                 CB 
                 GLU 
                 A 
                 116 
                 109.296 
                 36.769 
                 9.766 
                 1.00 
                 93.22 
                 C 
               
               
                 ATOM 
                 917 
                 CG 
                 GLU 
                 A 
                 116 
                 108.943 
                 38.140 
                 10.326 
                 1.00 
                 97.30 
                 C 
               
               
                 ATOM 
                 918 
                 CD 
                 GLU 
                 A 
                 116 
                 110.159 
                 39.000 
                 10.616 
                 1.00 
                 101.54 
                 C 
               
               
                 ATOM 
                 919 
                 OE1 
                 GLU 
                 A 
                 116 
                 111.055 
                 39.082 
                 9.748 
                 1.00 
                 107.29 
                 O 
               
               
                 ATOM 
                 920 
                 OE2 
                 GLU 
                 A 
                 116 
                 110.211 
                 39.609 
                 11.706 
                 1.00 
                 102.79 
                 O 
               
               
                 ATOM 
                 921 
                 C 
                 GLU 
                 A 
                 116 
                 109.524 
                 35.765 
                 12.065 
                 1.00 
                 93.80 
                 C 
               
               
                 ATOM 
                 922 
                 O 
                 GLU 
                 A 
                 116 
                 108.479 
                 35.132 
                 12.210 
                 1.00 
                 92.53 
                 O 
               
               
                 ATOM 
                 923 
                 N 
                 SER 
                 A 
                 117 
                 110.159 
                 36.358 
                 13.071 
                 1.00 
                 97.53 
                 N 
               
               
                 ATOM 
                 924 
                 CA 
                 SER 
                 A 
                 117 
                 109.664 
                 36.303 
                 14.448 
                 1.00 
                 97.24 
                 C 
               
               
                 ATOM 
                 925 
                 CB 
                 SER 
                 A 
                 117 
                 110.806 
                 36.585 
                 15.435 
                 1.00 
                 100.11 
                 C 
               
               
                 ATOM 
                 926 
                 OG 
                 SER 
                 A 
                 117 
                 111.643 
                 37.633 
                 14.972 
                 1.00 
                 105.40 
                 O 
               
               
                 ATOM 
                 927 
                 C 
                 SER 
                 A 
                 117 
                 108.489 
                 37.255 
                 14.694 
                 1.00 
                 95.90 
                 C 
               
               
                 ATOM 
                 928 
                 O 
                 SER 
                 A 
                 117 
                 107.653 
                 36.990 
                 15.558 
                 1.00 
                 94.55 
                 O 
               
               
                 ATOM 
                 929 
                 N 
                 ASP 
                 A 
                 118 
                 108.431 
                 38.358 
                 13.946 
                 1.00 
                 96.01 
                 N 
               
               
                 ATOM 
                 930 
                 CA 
                 ASP 
                 A 
                 118 
                 107.349 
                 39.340 
                 14.078 
                 1.00 
                 97.66 
                 C 
               
               
                 ATOM 
                 931 
                 CB 
                 ASP 
                 A 
                 118 
                 107.911 
                 40.765 
                 13.984 
                 1.00 
                 99.77 
                 C 
               
               
                 ATOM 
                 932 
                 CG 
                 ASP 
                 A 
                 118 
                 106.853 
                 41.842 
                 14.212 
                 1.00 
                 101.82 
                 C 
               
               
                 ATOM 
                 933 
                 OD1 
                 ASP 
                 A 
                 118 
                 105.746 
                 41.528 
                 14.704 
                 1.00 
                 103.70 
                 O 
               
               
                 ATOM 
                 934 
                 OD2 
                 ASP 
                 A 
                 118 
                 107.141 
                 43.018 
                 13.904 
                 1.00 
                 104.07 
                 O 
               
               
                 ATOM 
                 935 
                 C 
                 ASP 
                 A 
                 118 
                 106.288 
                 39.116 
                 12.999 
                 1.00 
                 97.06 
                 C 
               
               
                 ATOM 
                 936 
                 O 
                 ASP 
                 A 
                 118 
                 106.510 
                 39.421 
                 11.829 
                 1.00 
                 98.49 
                 O 
               
               
                 ATOM 
                 937 
                 N 
                 VAL 
                 A 
                 119 
                 105.130 
                 38.604 
                 13.408 
                 1.00 
                 96.94 
                 N 
               
               
                 ATOM 
                 938 
                 CA 
                 VAL 
                 A 
                 119 
                 104.030 
                 38.294 
                 12.483 
                 1.00 
                 97.43 
                 C 
               
               
                 ATOM 
                 939 
                 CB 
                 VAL 
                 A 
                 119 
                 102.807 
                 37.719 
                 13.242 
                 1.00 
                 99.06 
                 C 
               
               
                 ATOM 
                 940 
                 CG1 
                 VAL 
                 A 
                 119 
                 102.134 
                 38.786 
                 14.098 
                 1.00 
                 99.23 
                 C 
               
               
                 ATOM 
                 941 
                 CG2 
                 VAL 
                 A 
                 119 
                 101.810 
                 37.093 
                 12.276 
                 1.00 
                 100.11 
                 C 
               
               
                 ATOM 
                 942 
                 C 
                 VAL 
                 A 
                 119 
                 103.581 
                 39.492 
                 11.637 
                 1.00 
                 96.97 
                 C 
               
               
                 ATOM 
                 943 
                 O 
                 VAL 
                 A 
                 119 
                 103.140 
                 39.322 
                 10.500 
                 1.00 
                 96.72 
                 O 
               
               
                 ATOM 
                 944 
                 N 
                 ARG 
                 A 
                 120 
                 103.705 
                 40.695 
                 12.193 
                 1.00 
                 97.92 
                 N 
               
               
                 ATOM 
                 945 
                 CA 
                 ARG 
                 A 
                 120 
                 103.284 
                 41.919 
                 11.508 
                 1.00 
                 99.51 
                 C 
               
               
                 ATOM 
                 946 
                 CB 
                 ARG 
                 A 
                 120 
                 103.353 
                 43.115 
                 12.466 
                 1.00 
                 103.11 
                 C 
               
               
                 ATOM 
                 947 
                 CG 
                 ARG 
                 A 
                 120 
                 102.446 
                 43.008 
                 13.686 
                 1.00 
                 105.30 
                 C 
               
               
                 ATOM 
                 948 
                 CD 
                 ARG 
                 A 
                 120 
                 100.973 
                 43.100 
                 13.315 
                 1.00 
                 105.70 
                 C 
               
               
                 ATOM 
                 949 
                 NE 
                 ARG 
                 A 
                 120 
                 100.099 
                 42.829 
                 14.454 
                 1.00 
                 105.98 
                 N 
               
               
                 ATOM 
                 950 
                 CZ 
                 ARG 
                 A 
                 120 
                 98.769 
                 42.875 
                 14.415 
                 1.00 
                 106.94 
                 C 
               
               
                 ATOM 
                 951 
                 NH1 
                 ARG 
                 A 
                 120 
                 98.134 
                 43.189 
                 13.290 
                 1.00 
                 107.36 
                 N 
               
               
                 ATOM 
                 952 
                 NH2 
                 ARG 
                 A 
                 120 
                 98.066 
                 42.610 
                 15.511 
                 1.00 
                 108.34 
                 N 
               
               
                 ATOM 
                 953 
                 C 
                 ARG 
                 A 
                 120 
                 104.108 
                 42.222 
                 10.255 
                 1.00 
                 98.14 
                 C 
               
               
                 ATOM 
                 954 
                 O 
                 ARG 
                 A 
                 120 
                 103.621 
                 42.887 
                 9.341 
                 1.00 
                 98.42 
                 O 
               
               
                 ATOM 
                 955 
                 N 
                 LYS 
                 A 
                 121 
                 105.348 
                 41.739 
                 10.217 
                 1.00 
                 96.66 
                 N 
               
               
                 ATOM 
                 956 
                 CA 
                 LYS 
                 A 
                 121 
                 106.230 
                 41.955 
                 9.069 
                 1.00 
                 97.00 
                 C 
               
               
                 ATOM 
                 957 
                 CB 
                 LYS 
                 A 
                 121 
                 107.695 
                 41.967 
                 9.517 
                 1.00 
                 100.76 
                 C 
               
               
                 ATOM 
                 958 
                 CG 
                 LYS 
                 A 
                 121 
                 108.074 
                 43.177 
                 10.355 
                 1.00 
                 105.33 
                 C 
               
               
                 ATOM 
                 959 
                 CD 
                 LYS 
                 A 
                 121 
                 109.582 
                 43.288 
                 10.515 
                 1.00 
                 108.74 
                 C 
               
               
                 ATOM 
                 960 
                 CE 
                 LYS 
                 A 
                 121 
                 109.983 
                 44.630 
                 11.105 
                 1.00 
                 111.26 
                 C 
               
               
                 ATOM 
                 961 
                 NZ 
                 LYS 
                 A 
                 121 
                 111.458 
                 44.828 
                 11.062 
                 1.00 
                 114.12 
                 N 
               
               
                 ATOM 
                 962 
                 C 
                 LYS 
                 A 
                 121 
                 106.052 
                 40.929 
                 7.948 
                 1.00 
                 95.26 
                 C 
               
               
                 ATOM 
                 963 
                 O 
                 LYS 
                 A 
                 121 
                 106.583 
                 41.120 
                 6.854 
                 1.00 
                 97.97 
                 O 
               
               
                 ATOM 
                 964 
                 N 
                 ILE 
                 A 
                 122 
                 105.310 
                 39.853 
                 8.207 
                 1.00 
                 93.34 
                 N 
               
               
                 ATOM 
                 965 
                 CA 
                 ILE 
                 A 
                 122 
                 105.126 
                 38.788 
                 7.214 
                 1.00 
                 91.06 
                 C 
               
               
                 ATOM 
                 966 
                 CB 
                 ILE 
                 A 
                 122 
                 104.603 
                 37.482 
                 7.850 
                 1.00 
                 89.31 
                 C 
               
               
                 ATOM 
                 967 
                 CG1 
                 ILE 
                 A 
                 122 
                 105.591 
                 36.969 
                 8.900 
                 1.00 
                 90.30 
                 C 
               
               
                 ATOM 
                 968 
                 CD1 
                 ILE 
                 A 
                 122 
                 105.068 
                 35.813 
                 9.722 
                 1.00 
                 90.61 
                 C 
               
               
                 ATOM 
                 969 
                 CG2 
                 ILE 
                 A 
                 122 
                 104.398 
                 36.411 
                 6.784 
                 1.00 
                 87.46 
                 C 
               
               
                 ATOM 
                 970 
                 C 
                 ILE 
                 A 
                 122 
                 104.167 
                 39.215 
                 6.107 
                 1.00 
                 91.89 
                 C 
               
               
                 ATOM 
                 971 
                 O 
                 ILE 
                 A 
                 122 
                 103.072 
                 39.711 
                 6.378 
                 1.00 
                 92.60 
                 O 
               
               
                 ATOM 
                 972 
                 N 
                 LYS 
                 A 
                 123 
                 104.593 
                 39.000 
                 4.864 
                 1.00 
                 93.11 
                 N 
               
               
                 ATOM 
                 973 
                 CA 
                 LYS 
                 A 
                 123 
                 103.795 
                 39.318 
                 3.684 
                 1.00 
                 95.03 
                 C 
               
               
                 ATOM 
                 974 
                 CB 
                 LYS 
                 A 
                 123 
                 104.570 
                 40.271 
                 2.776 
                 1.00 
                 98.86 
                 C 
               
               
                 ATOM 
                 975 
                 CG 
                 LYS 
                 A 
                 123 
                 104.764 
                 41.651 
                 3.385 
                 1.00 
                 102.64 
                 C 
               
               
                 ATOM 
                 976 
                 CD 
                 LYS 
                 A 
                 123 
                 105.857 
                 42.439 
                 2.684 
                 1.00 
                 105.78 
                 C 
               
               
                 ATOM 
                 977 
                 CE 
                 LYS 
                 A 
                 123 
                 106.091 
                 43.771 
                 3.377 
                 1.00 
                 108.87 
                 C 
               
               
                 ATOM 
                 978 
                 NZ 
                 LYS 
                 A 
                 123 
                 107.317 
                 44.453 
                 2.879 
                 1.00 
                 111.78 
                 N 
               
               
                 ATOM 
                 979 
                 C 
                 LYS 
                 A 
                 123 
                 103.439 
                 38.027 
                 2.945 
                 1.00 
                 92.62 
                 C 
               
               
                 ATOM 
                 980 
                 O 
                 LYS 
                 A 
                 123 
                 104.125 
                 37.017 
                 3.103 
                 1.00 
                 91.55 
                 O 
               
               
                 ATOM 
                 981 
                 N 
                 PRO 
                 A 
                 124 
                 102.368 
                 38.053 
                 2.129 
                 1.00 
                 89.62 
                 N 
               
               
                 ATOM 
                 982 
                 CA 
                 PRO 
                 A 
                 124 
                 101.920 
                 36.841 
                 1.431 
                 1.00 
                 89.50 
                 C 
               
               
                 ATOM 
                 983 
                 CB 
                 PRO 
                 A 
                 124 
                 100.746 
                 37.338 
                 0.581 
                 1.00 
                 91.29 
                 C 
               
               
                 ATOM 
                 984 
                 CG 
                 PRO 
                 A 
                 124 
                 100.301 
                 38.592 
                 1.241 
                 1.00 
                 90.38 
                 C 
               
               
                 ATOM 
                 985 
                 CD 
                 PRO 
                 A 
                 124 
                 101.553 
                 39.220 
                 1.756 
                 1.00 
                 89.45 
                 C 
               
               
                 ATOM 
                 986 
                 C 
                 PRO 
                 A 
                 124 
                 102.984 
                 36.211 
                 0.536 
                 1.00 
                 89.46 
                 C 
               
               
                 ATOM 
                 987 
                 O 
                 PRO 
                 A 
                 124 
                 102.998 
                 34.994 
                 0.358 
                 1.00 
                 89.19 
                 O 
               
               
                 ATOM 
                 988 
                 N 
                 GLU 
                 A 
                 125 
                 103.867 
                 37.041 
                 −0.011 
                 1.00 
                 89.63 
                 N 
               
               
                 ATOM 
                 989 
                 CA 
                 GLU 
                 A 
                 125 
                 104.938 
                 36.569 
                 −0.881 
                 1.00 
                 89.62 
                 C 
               
               
                 ATOM 
                 990 
                 CB 
                 GLU 
                 A 
                 125 
                 105.574 
                 37.735 
                 −1.655 
                 1.00 
                 95.09 
                 C 
               
               
                 ATOM 
                 991 
                 CG 
                 GLU 
                 A 
                 125 
                 104.612 
                 38.588 
                 −2.484 
                 1.00 
                 99.97 
                 C 
               
               
                 ATOM 
                 992 
                 CD 
                 GLU 
                 A 
                 125 
                 103.940 
                 39.715 
                 −1.704 
                 1.00 
                 102.20 
                 C 
               
               
                 ATOM 
                 993 
                 OE1 
                 GLU 
                 A 
                 125 
                 104.465 
                 40.128 
                 −0.647 
                 1.00 
                 102.51 
                 O 
               
               
                 ATOM 
                 994 
                 OE2 
                 GLU 
                 A 
                 125 
                 102.882 
                 40.202 
                 −2.161 
                 1.00 
                 103.21 
                 O 
               
               
                 ATOM 
                 995 
                 C 
                 GLU 
                 A 
                 125 
                 106.033 
                 35.846 
                 −0.096 
                 1.00 
                 86.13 
                 C 
               
               
                 ATOM 
                 996 
                 O 
                 GLU 
                 A 
                 125 
                 106.828 
                 35.119 
                 −0.683 
                 1.00 
                 82.74 
                 O 
               
               
                 ATOM 
                 997 
                 N 
                 ASP 
                 A 
                 126 
                 106.077 
                 36.053 
                 1.221 
                 1.00 
                 86.04 
                 N 
               
               
                 ATOM 
                 998 
                 CA 
                 ASP 
                 A 
                 126 
                 107.130 
                 35.479 
                 2.067 
                 1.00 
                 83.80 
                 C 
               
               
                 ATOM 
                 999 
                 CB 
                 ASP 
                 A 
                 126 
                 107.259 
                 36.269 
                 3.375 
                 1.00 
                 86.37 
                 C 
               
               
                 ATOM 
                 1000 
                 CG 
                 ASP 
                 A 
                 126 
                 107.607 
                 37.735 
                 3.148 
                 1.00 
                 89.43 
                 C 
               
               
                 ATOM 
                 1001 
                 OD1 
                 ASP 
                 A 
                 126 
                 108.014 
                 38.095 
                 2.023 
                 1.00 
                 90.53 
                 O 
               
               
                 ATOM 
                 1002 
                 OD2 
                 ASP 
                 A 
                 126 
                 107.479 
                 38.529 
                 4.105 
                 1.00 
                 91.56 
                 O 
               
               
                 ATOM 
                 1003 
                 C 
                 ASP 
                 A 
                 126 
                 106.937 
                 33.997 
                 2.385 
                 1.00 
                 79.71 
                 C 
               
               
                 ATOM 
                 1004 
                 O 
                 ASP 
                 A 
                 126 
                 107.919 
                 33.277 
                 2.575 
                 1.00 
                 76.75 
                 O 
               
               
                 ATOM 
                 1005 
                 N 
                 PHE 
                 A 
                 127 
                 105.687 
                 33.539 
                 2.440 
                 1.00 
                 77.69 
                 N 
               
               
                 ATOM 
                 1006 
                 CA 
                 PHE 
                 A 
                 127 
                 105.406 
                 32.127 
                 2.739 
                 1.00 
                 76.03 
                 C 
               
               
                 ATOM 
                 1007 
                 CB 
                 PHE 
                 A 
                 127 
                 103.907 
                 31.876 
                 2.959 
                 1.00 
                 74.67 
                 C 
               
               
                 ATOM 
                 1008 
                 CG 
                 PHE 
                 A 
                 127 
                 103.461 
                 32.070 
                 4.377 
                 1.00 
                 74.73 
                 C 
               
               
                 ATOM 
                 1009 
                 CD1 
                 PHE 
                 A 
                 127 
                 103.999 
                 31.292 
                 5.392 
                 1.00 
                 75.69 
                 C 
               
               
                 ATOM 
                 1010 
                 CE1 
                 PHE 
                 A 
                 127 
                 103.590 
                 31.452 
                 6.703 
                 1.00 
                 75.83 
                 C 
               
               
                 ATOM 
                 1011 
                 CZ 
                 PHE 
                 A 
                 127 
                 102.619 
                 32.386 
                 7.014 
                 1.00 
                 75.24 
                 C 
               
               
                 ATOM 
                 1012 
                 CE2 
                 PHE 
                 A 
                 127 
                 102.064 
                 33.159 
                 6.012 
                 1.00 
                 75.56 
                 C 
               
               
                 ATOM 
                 1013 
                 CD2 
                 PHE 
                 A 
                 127 
                 102.481 
                 32.998 
                 4.700 
                 1.00 
                 74.80 
                 C 
               
               
                 ATOM 
                 1014 
                 C 
                 PHE 
                 A 
                 127 
                 105.929 
                 31.164 
                 1.670 
                 1.00 
                 76.28 
                 C 
               
               
                 ATOM 
                 1015 
                 O 
                 PHE 
                 A 
                 127 
                 105.753 
                 31.386 
                 0.471 
                 1.00 
                 74.14 
                 O 
               
               
                 ATOM 
                 1016 
                 N 
                 THR 
                 A 
                 128 
                 106.567 
                 30.093 
                 2.139 
                 1.00 
                 75.69 
                 N 
               
               
                 ATOM 
                 1017 
                 CA 
                 THR 
                 A 
                 128 
                 107.117 
                 29.044 
                 1.291 
                 1.00 
                 74.38 
                 C 
               
               
                 ATOM 
                 1018 
                 CB 
                 THR 
                 A 
                 128 
                 108.643 
                 28.953 
                 1.456 
                 1.00 
                 74.05 
                 C 
               
               
                 ATOM 
                 1019 
                 OG1 
                 THR 
                 A 
                 128 
                 109.244 
                 30.200 
                 1.090 
                 1.00 
                 74.56 
                 O 
               
               
                 ATOM 
                 1020 
                 CG2 
                 THR 
                 A 
                 128 
                 109.220 
                 27.834 
                 0.598 
                 1.00 
                 74.60 
                 C 
               
               
                 ATOM 
                 1021 
                 C 
                 THR 
                 A 
                 128 
                 106.526 
                 27.704 
                 1.708 
                 1.00 
                 74.11 
                 C 
               
               
                 ATOM 
                 1022 
                 O 
                 THR 
                 A 
                 128 
                 106.618 
                 27.328 
                 2.875 
                 1.00 
                 74.98 
                 O 
               
               
                 ATOM 
                 1023 
                 N 
                 VAL 
                 A 
                 129 
                 105.926 
                 26.987 
                 0.761 
                 1.00 
                 72.30 
                 N 
               
               
                 ATOM 
                 1024 
                 CA 
                 VAL 
                 A 
                 129 
                 105.366 
                 25.665 
                 1.040 
                 1.00 
                 70.81 
                 C 
               
               
                 ATOM 
                 1025 
                 CB 
                 VAL 
                 A 
                 129 
                 104.408 
                 25.200 
                 −0.075 
                 1.00 
                 69.00 
                 C 
               
               
                 ATOM 
                 1026 
                 CG1 
                 VAL 
                 A 
                 129 
                 103.927 
                 23.778 
                 0.179 
                 1.00 
                 68.01 
                 C 
               
               
                 ATOM 
                 1027 
                 CG2 
                 VAL 
                 A 
                 129 
                 103.226 
                 26.152 
                 −0.189 
                 1.00 
                 69.56 
                 C 
               
               
                 ATOM 
                 1028 
                 C 
                 VAL 
                 A 
                 129 
                 106.525 
                 24.682 
                 1.177 
                 1.00 
                 72.26 
                 C 
               
               
                 ATOM 
                 1029 
                 O 
                 VAL 
                 A 
                 129 
                 107.254 
                 24.448 
                 0.211 
                 1.00 
                 74.48 
                 O 
               
               
                 ATOM 
                 1030 
                 N 
                 PHE 
                 A 
                 130 
                 106.701 
                 24.129 
                 2.378 
                 1.00 
                 71.94 
                 N 
               
               
                 ATOM 
                 1031 
                 CA 
                 PHE 
                 A 
                 130 
                 107.815 
                 23.214 
                 2.656 
                 1.00 
                 71.73 
                 C 
               
               
                 ATOM 
                 1032 
                 CB 
                 PHE 
                 A 
                 130 
                 108.617 
                 23.687 
                 3.876 
                 1.00 
                 73.22 
                 C 
               
               
                 ATOM 
                 1033 
                 CG 
                 PHE 
                 A 
                 130 
                 107.899 
                 23.525 
                 5.185 
                 1.00 
                 73.63 
                 C 
               
               
                 ATOM 
                 1034 
                 CD1 
                 PHE 
                 A 
                 130 
                 107.111 
                 24.548 
                 5.692 
                 1.00 
                 74.85 
                 C 
               
               
                 ATOM 
                 1035 
                 CE1 
                 PHE 
                 A 
                 130 
                 106.451 
                 24.402 
                 6.902 
                 1.00 
                 76.17 
                 C 
               
               
                 ATOM 
                 1036 
                 CZ 
                 PHE 
                 A 
                 130 
                 106.577 
                 23.226 
                 7.620 
                 1.00 
                 75.83 
                 C 
               
               
                 ATOM 
                 1037 
                 CE2 
                 PHE 
                 A 
                 130 
                 107.363 
                 22.200 
                 7.125 
                 1.00 
                 75.44 
                 C 
               
               
                 ATOM 
                 1038 
                 CD2 
                 PHE 
                 A 
                 130 
                 108.022 
                 22.354 
                 5.918 
                 1.00 
                 74.02 
                 C 
               
               
                 ATOM 
                 1039 
                 C 
                 PHE 
                 A 
                 130 
                 107.387 
                 21.760 
                 2.844 
                 1.00 
                 71.33 
                 C 
               
               
                 ATOM 
                 1040 
                 O 
                 PHE 
                 A 
                 130 
                 108.229 
                 20.862 
                 2.806 
                 1.00 
                 70.69 
                 O 
               
               
                 ATOM 
                 1041 
                 N 
                 SER 
                 A 
                 131 
                 106.094 
                 21.525 
                 3.053 
                 1.00 
                 70.85 
                 N 
               
               
                 ATOM 
                 1042 
                 CA 
                 SER 
                 A 
                 131 
                 105.587 
                 20.165 
                 3.209 
                 1.00 
                 71.30 
                 C 
               
               
                 ATOM 
                 1043 
                 CB 
                 SER 
                 A 
                 131 
                 105.675 
                 19.720 
                 4.669 
                 1.00 
                 73.51 
                 C 
               
               
                 ATOM 
                 1044 
                 OG 
                 SER 
                 A 
                 131 
                 105.301 
                 18.360 
                 4.805 
                 1.00 
                 74.55 
                 O 
               
               
                 ATOM 
                 1045 
                 C 
                 SER 
                 A 
                 131 
                 104.149 
                 20.060 
                 2.719 
                 1.00 
                 69.79 
                 C 
               
               
                 ATOM 
                 1046 
                 O 
                 SER 
                 A 
                 131 
                 103.352 
                 20.980 
                 2.901 
                 1.00 
                 67.79 
                 O 
               
               
                 ATOM 
                 1047 
                 N 
                 VAL 
                 A 
                 132 
                 103.834 
                 18.924 
                 2.103 
                 1.00 
                 70.57 
                 N 
               
               
                 ATOM 
                 1048 
                 CA 
                 VAL 
                 A 
                 132 
                 102.519 
                 18.674 
                 1.518 
                 1.00 
                 70.58 
                 C 
               
               
                 ATOM 
                 1049 
                 CB 
                 VAL 
                 A 
                 132 
                 102.561 
                 18.867 
                 −0.020 
                 1.00 
                 69.36 
                 C 
               
               
                 ATOM 
                 1050 
                 CG1 
                 VAL 
                 A 
                 132 
                 101.234 
                 18.487 
                 −0.664 
                 1.00 
                 69.12 
                 C 
               
               
                 ATOM 
                 1051 
                 CG2 
                 VAL 
                 A 
                 132 
                 102.931 
                 20.302 
                 −0.365 
                 1.00 
                 69.14 
                 C 
               
               
                 ATOM 
                 1052 
                 C 
                 VAL 
                 A 
                 132 
                 102.070 
                 17.248 
                 1.819 
                 1.00 
                 70.20 
                 C 
               
               
                 ATOM 
                 1053 
                 O 
                 VAL 
                 A 
                 132 
                 102.897 
                 16.343 
                 1.946 
                 1.00 
                 72.95 
                 O 
               
               
                 ATOM 
                 1054 
                 N 
                 ASN 
                 A 
                 133 
                 100.760 
                 17.067 
                 1.957 
                 1.00 
                 68.16 
                 N 
               
               
                 ATOM 
                 1055 
                 CA 
                 ASN 
                 A 
                 133 
                 100.165 
                 15.743 
                 2.071 
                 1.00 
                 70.49 
                 C 
               
               
                 ATOM 
                 1056 
                 CB 
                 ASN 
                 A 
                 133 
                 99.778 
                 15.417 
                 3.514 
                 1.00 
                 72.09 
                 C 
               
               
                 ATOM 
                 1057 
                 CG 
                 ASN 
                 A 
                 133 
                 99.396 
                 13.956 
                 3.699 
                 1.00 
                 72.52 
                 C 
               
               
                 ATOM 
                 1058 
                 OD1 
                 ASN 
                 A 
                 133 
                 98.600 
                 13.412 
                 2.932 
                 1.00 
                 72.44 
                 O 
               
               
                 ATOM 
                 1059 
                 ND2 
                 ASN 
                 A 
                 133 
                 99.962 
                 13.316 
                 4.724 
                 1.00 
                 74.04 
                 N 
               
               
                 ATOM 
                 1060 
                 C 
                 ASN 
                 A 
                 133 
                 98.955 
                 15.720 
                 1.148 
                 1.00 
                 72.68 
                 C 
               
               
                 ATOM 
                 1061 
                 O 
                 ASN 
                 A 
                 133 
                 97.956 
                 16.379 
                 1.414 
                 1.00 
                 73.03 
                 O 
               
               
                 ATOM 
                 1062 
                 N 
                 GLN 
                 A 
                 134 
                 99.057 
                 14.969 
                 0.056 
                 1.00 
                 74.63 
                 N 
               
               
                 ATOM 
                 1063 
                 CA 
                 GLN 
                 A 
                 134 
                 98.015 
                 14.954 
                 −0.969 
                 1.00 
                 74.97 
                 C 
               
               
                 ATOM 
                 1064 
                 CB 
                 GLN 
                 A 
                 134 
                 98.548 
                 14.351 
                 −2.269 
                 1.00 
                 76.21 
                 C 
               
               
                 ATOM 
                 1065 
                 CG 
                 GLN 
                 A 
                 134 
                 99.637 
                 15.191 
                 −2.909 
                 1.00 
                 77.57 
                 C 
               
               
                 ATOM 
                 1066 
                 CD 
                 GLN 
                 A 
                 134 
                 100.043 
                 14.681 
                 −4.275 
                 1.00 
                 80.24 
                 C 
               
               
                 ATOM 
                 1067 
                 OE1 
                 GLN 
                 A 
                 134 
                 99.592 
                 13.623 
                 −4.718 
                 1.00 
                 82.97 
                 O 
               
               
                 ATOM 
                 1068 
                 NE2 
                 GLN 
                 A 
                 134 
                 100.902 
                 15.434 
                 −4.952 
                 1.00 
                 81.02 
                 N 
               
               
                 ATOM 
                 1069 
                 C 
                 GLN 
                 A 
                 134 
                 96.732 
                 14.247 
                 −0.554 
                 1.00 
                 74.40 
                 C 
               
               
                 ATOM 
                 1070 
                 O 
                 GLN 
                 A 
                 134 
                 95.684 
                 14.473 
                 −1.157 
                 1.00 
                 80.04 
                 O 
               
               
                 ATOM 
                 1071 
                 N 
                 THR 
                 A 
                 135 
                 96.812 
                 13.384 
                 0.452 
                 1.00 
                 74.31 
                 N 
               
               
                 ATOM 
                 1072 
                 CA 
                 THR 
                 A 
                 135 
                 95.631 
                 12.701 
                 0.965 
                 1.00 
                 77.03 
                 C 
               
               
                 ATOM 
                 1073 
                 CB 
                 THR 
                 A 
                 135 
                 95.939 
                 11.235 
                 1.327 
                 1.00 
                 75.26 
                 C 
               
               
                 ATOM 
                 1074 
                 OG1 
                 THR 
                 A 
                 135 
                 96.708 
                 10.634 
                 0.280 
                 1.00 
                 74.35 
                 O 
               
               
                 ATOM 
                 1075 
                 CG2 
                 THR 
                 A 
                 135 
                 94.652 
                 10.444 
                 1.522 
                 1.00 
                 75.12 
                 C 
               
               
                 ATOM 
                 1076 
                 C 
                 THR 
                 A 
                 135 
                 95.165 
                 13.486 
                 2.190 
                 1.00 
                 82.39 
                 C 
               
               
                 ATOM 
                 1077 
                 O 
                 THR 
                 A 
                 135 
                 95.116 
                 12.959 
                 3.307 
                 1.00 
                 82.05 
                 O 
               
               
                 ATOM 
                 1078 
                 N 
                 CYS 
                 A 
                 136 
                 94.824 
                 14.756 
                 1.972 
                 1.00 
                 84.83 
                 N 
               
               
                 ATOM 
                 1079 
                 CA 
                 CYS 
                 A 
                 136 
                 94.499 
                 15.645 
                 3.077 
                 1.00 
                 86.52 
                 C 
               
               
                 ATOM 
                 1080 
                 CB 
                 CYS 
                 A 
                 136 
                 95.175 
                 16.990 
                 2.920 
                 1.00 
                 86.38 
                 C 
               
               
                 ATOM 
                 1081 
                 SG 
                 CYS 
                 A 
                 136 
                 94.984 
                 17.997 
                 4.401 
                 1.00 
                 83.29 
                 S 
               
               
                 ATOM 
                 1082 
                 C 
                 CYS 
                 A 
                 136 
                 93.022 
                 15.895 
                 3.277 
                 1.00 
                 90.46 
                 C 
               
               
                 ATOM 
                 1083 
                 O 
                 CYS 
                 A 
                 136 
                 92.241 
                 15.963 
                 2.326 
                 1.00 
                 85.99 
                 O 
               
               
                 ATOM 
                 1084 
                 N 
                 VAL 
                 A 
                 137 
                 92.688 
                 16.096 
                 4.548 
                 1.00 
                 94.32 
                 N 
               
               
                 ATOM 
                 1085 
                 CA 
                 VAL 
                 A 
                 137 
                 91.324 
                 16.244 
                 5.012 
                 1.00 
                 87.90 
                 C 
               
               
                 ATOM 
                 1086 
                 CB 
                 VAL 
                 A 
                 137 
                 90.656 
                 17.503 
                 4.443 
                 1.00 
                 88.76 
                 C 
               
               
                 ATOM 
                 1087 
                 CG1 
                 VAL 
                 A 
                 137 
                 89.238 
                 17.622 
                 4.957 
                 1.00 
                 94.38 
                 C 
               
               
                 ATOM 
                 1088 
                 CG2 
                 VAL 
                 A 
                 137 
                 91.460 
                 18.733 
                 4.840 
                 1.00 
                 86.92 
                 C 
               
               
                 ATOM 
                 1089 
                 C 
                 VAL 
                 A 
                 137 
                 90.590 
                 14.932 
                 4.727 
                 1.00 
                 85.62 
                 C 
               
               
                 ATOM 
                 1090 
                 O 
                 VAL 
                 A 
                 137 
                 89.553 
                 14.884 
                 4.065 
                 1.00 
                 85.99 
                 O 
               
               
                 ATOM 
                 1091 
                 N 
                 TRP 
                 A 
                 138 
                 91.219 
                 13.862 
                 5.207 
                 1.00 
                 81.26 
                 N 
               
               
                 ATOM 
                 1092 
                 CA 
                 TRP 
                 A 
                 138 
                 90.633 
                 12.533 
                 5.250 
                 1.00 
                 80.06 
                 C 
               
               
                 ATOM 
                 1093 
                 CB 
                 TRP 
                 A 
                 138 
                 91.206 
                 11.622 
                 4.161 
                 1.00 
                 78.20 
                 C 
               
               
                 ATOM 
                 1094 
                 CG 
                 TRP 
                 A 
                 138 
                 90.416 
                 10.367 
                 4.023 
                 1.00 
                 74.91 
                 C 
               
               
                 ATOM 
                 1095 
                 CD1 
                 TRP 
                 A 
                 138 
                 90.803 
                 9.111 
                 4.369 
                 1.00 
                 74.39 
                 C 
               
               
                 ATOM 
                 1096 
                 NE1 
                 TRP 
                 A 
                 138 
                 89.790 
                 8.218 
                 4.115 
                 1.00 
                 76.74 
                 N 
               
               
                 ATOM 
                 1097 
                 CE2 
                 TRP 
                 A 
                 138 
                 88.714 
                 8.900 
                 3.612 
                 1.00 
                 76.01 
                 C 
               
               
                 ATOM 
                 1098 
                 CD2 
                 TRP 
                 A 
                 138 
                 89.073 
                 10.259 
                 3.545 
                 1.00 
                 74.70 
                 C 
               
               
                 ATOM 
                 1099 
                 CE3 
                 TRP 
                 A 
                 138 
                 88.142 
                 11.181 
                 3.055 
                 1.00 
                 74.89 
                 C 
               
               
                 ATOM 
                 1100 
                 CZ3 
                 TRP 
                 A 
                 138 
                 86.896 
                 10.722 
                 2.655 
                 1.00 
                 76.10 
                 C 
               
               
                 ATOM 
                 1101 
                 CH2 
                 TRP 
                 A 
                 138 
                 86.567 
                 9.361 
                 2.733 
                 1.00 
                 77.44 
                 C 
               
               
                 ATOM 
                 1102 
                 CZ2 
                 TRP 
                 A 
                 138 
                 87.460 
                 8.436 
                 3.207 
                 1.00 
                 77.43 
                 C 
               
               
                 ATOM 
                 1103 
                 C 
                 TRP 
                 A 
                 138 
                 90.904 
                 11.958 
                 6.643 
                 1.00 
                 80.76 
                 C 
               
               
                 ATOM 
                 1104 
                 O 
                 TRP 
                 A 
                 138 
                 89.991 
                 11.459 
                 7.303 
                 1.00 
                 79.36 
                 O 
               
               
                 ATOM 
                 1105 
                 N 
                 TYR 
                 A 
                 139 
                 92.166 
                 12.034 
                 7.071 
                 1.00 
                 82.51 
                 N 
               
               
                 ATOM 
                 1106 
                 CA 
                 TYR 
                 A 
                 139 
                 92.581 
                 11.601 
                 8.401 
                 1.00 
                 81.56 
                 C 
               
               
                 ATOM 
                 1107 
                 CB 
                 TYR 
                 A 
                 139 
                 93.916 
                 10.861 
                 8.339 
                 1.00 
                 80.89 
                 C 
               
               
                 ATOM 
                 1108 
                 CG 
                 TYR 
                 A 
                 139 
                 94.018 
                 9.811 
                 7.257 
                 1.00 
                 80.17 
                 C 
               
               
                 ATOM 
                 1109 
                 CD1 
                 TYR 
                 A 
                 139 
                 93.330 
                 8.606 
                 7.359 
                 1.00 
                 80.27 
                 C 
               
               
                 ATOM 
                 1110 
                 CE1 
                 TYR 
                 A 
                 139 
                 93.437 
                 7.637 
                 6.374 
                 1.00 
                 82.65 
                 C 
               
               
                 ATOM 
                 1111 
                 CZ 
                 TYR 
                 A 
                 139 
                 94.248 
                 7.865 
                 5.272 
                 1.00 
                 81.80 
                 C 
               
               
                 ATOM 
                 1112 
                 OH 
                 TYR 
                 A 
                 139 
                 94.359 
                 6.909 
                 4.287 
                 1.00 
                 81.17 
                 O 
               
               
                 ATOM 
                 1113 
                 CE2 
                 TYR 
                 A 
                 139 
                 94.946 
                 9.050 
                 5.155 
                 1.00 
                 80.06 
                 C 
               
               
                 ATOM 
                 1114 
                 CD2 
                 TYR 
                 A 
                 139 
                 94.832 
                 10.011 
                 6.144 
                 1.00 
                 79.78 
                 C 
               
               
                 ATOM 
                 1115 
                 C 
                 TYR 
                 A 
                 139 
                 92.750 
                 12.826 
                 9.296 
                 1.00 
                 81.52 
                 C 
               
               
                 ATOM 
                 1116 
                 O 
                 TYR 
                 A 
                 139 
                 93.288 
                 13.844 
                 8.860 
                 1.00 
                 82.26 
                 O 
               
               
                 ATOM 
                 1117 
                 N 
                 ARG 
                 A 
                 140 
                 92.303 
                 12.717 
                 10.546 
                 1.00 
                 81.61 
                 N 
               
               
                 ATOM 
                 1118 
                 CA 
                 ARG 
                 A 
                 140 
                 92.458 
                 13.798 
                 11.522 
                 1.00 
                 80.81 
                 C 
               
               
                 ATOM 
                 1119 
                 CB 
                 ARG 
                 A 
                 140 
                 91.682 
                 13.503 
                 12.802 
                 1.00 
                 80.92 
                 C 
               
               
                 ATOM 
                 1120 
                 CG 
                 ARG 
                 A 
                 140 
                 91.965 
                 14.496 
                 13.916 
                 1.00 
                 81.79 
                 C 
               
               
                 ATOM 
                 1121 
                 CD 
                 ARG 
                 A 
                 140 
                 90.903 
                 14.448 
                 14.997 
                 1.00 
                 85.18 
                 C 
               
               
                 ATOM 
                 1122 
                 NE 
                 ARG 
                 A 
                 140 
                 90.964 
                 13.227 
                 15.803 
                 1.00 
                 86.47 
                 N 
               
               
                 ATOM 
                 1123 
                 CZ 
                 ARG 
                 A 
                 140 
                 91.715 
                 13.062 
                 16.892 
                 1.00 
                 84.38 
                 C 
               
               
                 ATOM 
                 1124 
                 NH1 
                 ARG 
                 A 
                 140 
                 91.672 
                 11.905 
                 17.545 
                 1.00 
                 85.39 
                 N 
               
               
                 ATOM 
                 1125 
                 NH2 
                 ARG 
                 A 
                 140 
                 92.506 
                 14.034 
                 17.339 
                 1.00 
                 83.04 
                 N 
               
               
                 ATOM 
                 1126 
                 C 
                 ARG 
                 A 
                 140 
                 93.927 
                 14.003 
                 11.857 
                 1.00 
                 79.50 
                 C 
               
               
                 ATOM 
                 1127 
                 O 
                 ARG 
                 A 
                 140 
                 94.402 
                 15.133 
                 11.904 
                 1.00 
                 79.49 
                 O 
               
               
                 ATOM 
                 1128 
                 N 
                 PHE 
                 A 
                 141 
                 94.631 
                 12.903 
                 12.110 
                 1.00 
                 78.69 
                 N 
               
               
                 ATOM 
                 1129 
                 CA 
                 PHE 
                 A 
                 141 
                 96.063 
                 12.951 
                 12.362 
                 1.00 
                 78.46 
                 C 
               
               
                 ATOM 
                 1130 
                 CB 
                 PHE 
                 A 
                 141 
                 96.504 
                 11.793 
                 13.256 
                 1.00 
                 79.59 
                 C 
               
               
                 ATOM 
                 1131 
                 CG 
                 PHE 
                 A 
                 141 
                 95.953 
                 11.862 
                 14.650 
                 1.00 
                 80.07 
                 C 
               
               
                 ATOM 
                 1132 
                 CD1 
                 PHE 
                 A 
                 141 
                 96.507 
                 12.721 
                 15.588 
                 1.00 
                 80.90 
                 C 
               
               
                 ATOM 
                 1133 
                 CE1 
                 PHE 
                 A 
                 141 
                 96.005 
                 12.785 
                 16.875 
                 1.00 
                 83.01 
                 C 
               
               
                 ATOM 
                 1134 
                 CZ 
                 PHE 
                 A 
                 141 
                 94.941 
                 11.980 
                 17.240 
                 1.00 
                 82.71 
                 C 
               
               
                 ATOM 
                 1135 
                 CE2 
                 PHE 
                 A 
                 141 
                 94.382 
                 11.119 
                 16.314 
                 1.00 
                 82.15 
                 C 
               
               
                 ATOM 
                 1136 
                 CD2 
                 PHE 
                 A 
                 141 
                 94.888 
                 11.062 
                 15.029 
                 1.00 
                 81.39 
                 C 
               
               
                 ATOM 
                 1137 
                 C 
                 PHE 
                 A 
                 141 
                 96.782 
                 12.898 
                 11.022 
                 1.00 
                 77.36 
                 C 
               
               
                 ATOM 
                 1138 
                 O 
                 PHE 
                 A 
                 141 
                 97.094 
                 11.821 
                 10.518 
                 1.00 
                 77.71 
                 O 
               
               
                 ATOM 
                 1139 
                 N 
                 THR 
                 A 
                 142 
                 97.023 
                 14.072 
                 10.447 
                 1.00 
                 76.07 
                 N 
               
               
                 ATOM 
                 1140 
                 CA 
                 THR 
                 A 
                 142 
                 97.678 
                 14.188 
                 9.150 
                 1.00 
                 76.31 
                 C 
               
               
                 ATOM 
                 1141 
                 CB 
                 THR 
                 A 
                 142 
                 96.990 
                 15.256 
                 8.278 
                 1.00 
                 76.58 
                 C 
               
               
                 ATOM 
                 1142 
                 OG1 
                 THR 
                 A 
                 142 
                 95.643 
                 14.850 
                 7.996 
                 1.00 
                 77.62 
                 O 
               
               
                 ATOM 
                 1143 
                 CG2 
                 THR 
                 A 
                 142 
                 97.737 
                 15.450 
                 6.964 
                 1.00 
                 77.49 
                 C 
               
               
                 ATOM 
                 1144 
                 C 
                 THR 
                 A 
                 142 
                 99.147 
                 14.545 
                 9.334 
                 1.00 
                 76.47 
                 C 
               
               
                 ATOM 
                 1145 
                 O 
                 THR 
                 A 
                 142 
                 99.472 
                 15.623 
                 9.829 
                 1.00 
                 76.20 
                 O 
               
               
                 ATOM 
                 1146 
                 N 
                 ASP 
                 A 
                 143 
                 100.027 
                 13.633 
                 8.927 
                 1.00 
                 77.81 
                 N 
               
               
                 ATOM 
                 1147 
                 CA 
                 ASP 
                 A 
                 143 
                 101.468 
                 13.842 
                 9.038 
                 1.00 
                 78.46 
                 C 
               
               
                 ATOM 
                 1148 
                 CB 
                 ASP 
                 A 
                 143 
                 102.212 
                 12.500 
                 9.032 
                 1.00 
                 81.65 
                 C 
               
               
                 ATOM 
                 1149 
                 CG 
                 ASP 
                 A 
                 143 
                 101.879 
                 11.633 
                 10.239 
                 1.00 
                 83.58 
                 C 
               
               
                 ATOM 
                 1150 
                 OD1 
                 ASP 
                 A 
                 143 
                 101.038 
                 12.040 
                 11.070 
                 1.00 
                 85.51 
                 O 
               
               
                 ATOM 
                 1151 
                 OD2 
                 ASP 
                 A 
                 143 
                 102.467 
                 10.539 
                 10.354 
                 1.00 
                 84.80 
                 O 
               
               
                 ATOM 
                 1152 
                 C 
                 ASP 
                 A 
                 143 
                 101.993 
                 14.713 
                 7.903 
                 1.00 
                 74.97 
                 C 
               
               
                 ATOM 
                 1153 
                 O 
                 ASP 
                 A 
                 143 
                 101.479 
                 14.670 
                 6.785 
                 1.00 
                 77.14 
                 O 
               
               
                 ATOM 
                 1154 
                 N 
                 PHE 
                 A 
                 144 
                 103.021 
                 15.498 
                 8.210 
                 1.00 
                 71.79 
                 N 
               
               
                 ATOM 
                 1155 
                 CA 
                 PHE 
                 A 
                 144 
                 103.688 
                 16.348 
                 7.237 
                 1.00 
                 71.00 
                 C 
               
               
                 ATOM 
                 1156 
                 CB 
                 PHE 
                 A 
                 144 
                 103.379 
                 17.820 
                 7.507 
                 1.00 
                 69.59 
                 C 
               
               
                 ATOM 
                 1157 
                 CG 
                 PHE 
                 A 
                 144 
                 101.965 
                 18.210 
                 7.182 
                 1.00 
                 69.05 
                 C 
               
               
                 ATOM 
                 1158 
                 CD1 
                 PHE 
                 A 
                 144 
                 100.983 
                 18.185 
                 8.158 
                 1.00 
                 69.25 
                 C 
               
               
                 ATOM 
                 1159 
                 CE1 
                 PHE 
                 A 
                 144 
                 99.678 
                 18.543 
                 7.860 
                 1.00 
                 69.31 
                 C 
               
               
                 ATOM 
                 1160 
                 CZ 
                 PHE 
                 A 
                 144 
                 99.341 
                 18.931 
                 6.577 
                 1.00 
                 67.47 
                 C 
               
               
                 ATOM 
                 1161 
                 CE2 
                 PHE 
                 A 
                 144 
                 100.311 
                 18.962 
                 5.593 
                 1.00 
                 67.42 
                 C 
               
               
                 ATOM 
                 1162 
                 CD2 
                 PHE 
                 A 
                 144 
                 101.614 
                 18.600 
                 5.896 
                 1.00 
                 68.29 
                 C 
               
               
                 ATOM 
                 1163 
                 C 
                 PHE 
                 A 
                 144 
                 105.190 
                 16.100 
                 7.311 
                 1.00 
                 73.12 
                 C 
               
               
                 ATOM 
                 1164 
                 O 
                 PHE 
                 A 
                 144 
                 105.820 
                 16.379 
                 8.328 
                 1.00 
                 71.85 
                 O 
               
               
                 ATOM 
                 1165 
                 N 
                 GLN 
                 A 
                 145 
                 105.755 
                 15.570 
                 6.227 
                 1.00 
                 78.05 
                 N 
               
               
                 ATOM 
                 1166 
                 CA 
                 GLN 
                 A 
                 145 
                 107.182 
                 15.262 
                 6.170 
                 1.00 
                 77.96 
                 C 
               
               
                 ATOM 
                 1167 
                 CB 
                 GLN 
                 A 
                 145 
                 107.504 
                 14.360 
                 4.975 
                 1.00 
                 80.55 
                 C 
               
               
                 ATOM 
                 1168 
                 CG 
                 GLN 
                 A 
                 145 
                 106.704 
                 13.064 
                 4.915 
                 1.00 
                 82.81 
                 C 
               
               
                 ATOM 
                 1169 
                 CD 
                 GLN 
                 A 
                 145 
                 106.892 
                 12.190 
                 6.142 
                 1.00 
                 85.81 
                 C 
               
               
                 ATOM 
                 1170 
                 OE1 
                 GLN 
                 A 
                 145 
                 107.994 
                 12.091 
                 6.688 
                 1.00 
                 87.14 
                 O 
               
               
                 ATOM 
                 1171 
                 NE2 
                 GLN 
                 A 
                 145 
                 105.816 
                 11.537 
                 6.575 
                 1.00 
                 87.99 
                 N 
               
               
                 ATOM 
                 1172 
                 C 
                 GLN 
                 A 
                 145 
                 107.965 
                 16.559 
                 6.056 
                 1.00 
                 76.90 
                 C 
               
               
                 ATOM 
                 1173 
                 O 
                 GLN 
                 A 
                 145 
                 107.702 
                 17.368 
                 5.168 
                 1.00 
                 77.08 
                 O 
               
               
                 ATOM 
                 1174 
                 N 
                 VAL 
                 A 
                 146 
                 108.920 
                 16.754 
                 6.961 
                 1.00 
                 75.97 
                 N 
               
               
                 ATOM 
                 1175 
                 CA 
                 VAL 
                 A 
                 146 
                 109.732 
                 17.964 
                 6.982 
                 1.00 
                 75.59 
                 C 
               
               
                 ATOM 
                 1176 
                 CB 
                 VAL 
                 A 
                 146 
                 110.064 
                 18.389 
                 8.425 
                 1.00 
                 75.15 
                 C 
               
               
                 ATOM 
                 1177 
                 CG1 
                 VAL 
                 A 
                 146 
                 110.804 
                 19.720 
                 8.442 
                 1.00 
                 75.39 
                 C 
               
               
                 ATOM 
                 1178 
                 CG2 
                 VAL 
                 A 
                 146 
                 108.795 
                 18.483 
                 9.259 
                 1.00 
                 74.27 
                 C 
               
               
                 ATOM 
                 1179 
                 C 
                 VAL 
                 A 
                 146 
                 111.029 
                 17.690 
                 6.231 
                 1.00 
                 76.30 
                 C 
               
               
                 ATOM 
                 1180 
                 O 
                 VAL 
                 A 
                 146 
                 111.608 
                 16.613 
                 6.385 
                 1.00 
                 76.96 
                 O 
               
               
                 ATOM 
                 1181 
                 N 
                 PRO 
                 A 
                 147 
                 111.487 
                 18.649 
                 5.404 
                 1.00 
                 78.68 
                 N 
               
               
                 ATOM 
                 1182 
                 CA 
                 PRO 
                 A 
                 147 
                 112.755 
                 18.431 
                 4.701 
                 1.00 
                 81.84 
                 C 
               
               
                 ATOM 
                 1183 
                 CB 
                 PRO 
                 A 
                 147 
                 112.881 
                 19.659 
                 3.787 
                 1.00 
                 80.60 
                 C 
               
               
                 ATOM 
                 1184 
                 CG 
                 PRO 
                 A 
                 147 
                 111.513 
                 20.234 
                 3.693 
                 1.00 
                 79.84 
                 C 
               
               
                 ATOM 
                 1185 
                 CD 
                 PRO 
                 A 
                 147 
                 110.823 
                 19.894 
                 4.977 
                 1.00 
                 79.51 
                 C 
               
               
                 ATOM 
                 1186 
                 C 
                 PRO 
                 A 
                 147 
                 113.941 
                 18.347 
                 5.661 
                 1.00 
                 86.08 
                 C 
               
               
                 ATOM 
                 1187 
                 O 
                 PRO 
                 A 
                 147 
                 113.938 
                 19.000 
                 6.706 
                 1.00 
                 86.09 
                 O 
               
               
                 ATOM 
                 1188 
                 N 
                 GLU 
                 A 
                 148 
                 114.939 
                 17.545 
                 5.307 
                 1.00 
                 91.96 
                 N 
               
               
                 ATOM 
                 1189 
                 CA 
                 GLU 
                 A 
                 148 
                 116.120 
                 17.368 
                 6.150 
                 1.00 
                 97.64 
                 C 
               
               
                 ATOM 
                 1190 
                 CB 
                 GLU 
                 A 
                 148 
                 116.968 
                 16.200 
                 5.636 
                 1.00 
                 101.74 
                 C 
               
               
                 ATOM 
                 1191 
                 CG 
                 GLU 
                 A 
                 148 
                 118.213 
                 15.911 
                 6.463 
                 1.00 
                 107.11 
                 C 
               
               
                 ATOM 
                 1192 
                 CD 
                 GLU 
                 A 
                 148 
                 119.079 
                 14.827 
                 5.853 
                 1.00 
                 113.41 
                 C 
               
               
                 ATOM 
                 1193 
                 OE1 
                 GLU 
                 A 
                 148 
                 118.525 
                 13.806 
                 5.393 
                 1.00 
                 120.31 
                 O 
               
               
                 ATOM 
                 1194 
                 OE2 
                 GLU 
                 A 
                 148 
                 120.318 
                 14.993 
                 5.842 
                 1.00 
                 118.08 
                 O 
               
               
                 ATOM 
                 1195 
                 C 
                 GLU 
                 A 
                 148 
                 116.971 
                 18.637 
                 6.223 
                 1.00 
                 98.80 
                 C 
               
               
                 ATOM 
                 1196 
                 O 
                 GLU 
                 A 
                 148 
                 117.497 
                 18.973 
                 7.284 
                 1.00 
                 99.60 
                 O 
               
               
                 ATOM 
                 1197 
                 N 
                 ARG 
                 A 
                 149 
                 117.092 
                 19.345 
                 5.102 
                 1.00 
                 100.31 
                 N 
               
               
                 ATOM 
                 1198 
                 CA 
                 ARG 
                 A 
                 149 
                 117.944 
                 20.535 
                 5.026 
                 1.00 
                 102.05 
                 C 
               
               
                 ATOM 
                 1199 
                 CB 
                 ARG 
                 A 
                 149 
                 118.496 
                 20.691 
                 3.602 
                 1.00 
                 109.61 
                 C 
               
               
                 ATOM 
                 1200 
                 CG 
                 ARG 
                 A 
                 149 
                 119.367 
                 19.534 
                 3.140 
                 1.00 
                 116.76 
                 C 
               
               
                 ATOM 
                 1201 
                 CD 
                 ARG 
                 A 
                 149 
                 119.858 
                 19.745 
                 1.716 
                 1.00 
                 125.71 
                 C 
               
               
                 ATOM 
                 1202 
                 NE 
                 ARG 
                 A 
                 149 
                 120.677 
                 18.626 
                 1.239 
                 1.00 
                 133.21 
                 N 
               
               
                 ATOM 
                 1203 
                 CZ 
                 ARG 
                 A 
                 149 
                 121.985 
                 18.479 
                 1.460 
                 1.00 
                 133.30 
                 C 
               
               
                 ATOM 
                 1204 
                 NH1 
                 ARG 
                 A 
                 149 
                 122.666 
                 19.375 
                 2.173 
                 1.00 
                 135.95 
                 N 
               
               
                 ATOM 
                 1205 
                 NH2 
                 ARG 
                 A 
                 149 
                 122.619 
                 17.417 
                 0.970 
                 1.00 
                 129.76 
                 N 
               
               
                 ATOM 
                 1206 
                 C 
                 ARG 
                 A 
                 149 
                 117.261 
                 21.839 
                 5.471 
                 1.00 
                 96.88 
                 C 
               
               
                 ATOM 
                 1207 
                 O 
                 ARG 
                 A 
                 149 
                 117.676 
                 22.925 
                 5.055 
                 1.00 
                 95.81 
                 O 
               
               
                 ATOM 
                 1208 
                 N 
                 MET 
                 A 
                 150 
                 116.233 
                 21.746 
                 6.316 
                 1.00 
                 90.98 
                 N 
               
               
                 ATOM 
                 1209 
                 CA 
                 MET 
                 A 
                 150 
                 115.560 
                 22.943 
                 6.824 
                 1.00 
                 89.04 
                 C 
               
               
                 ATOM 
                 1210 
                 CB 
                 MET 
                 A 
                 150 
                 114.235 
                 22.594 
                 7.512 
                 1.00 
                 88.98 
                 C 
               
               
                 ATOM 
                 1211 
                 CG 
                 MET 
                 A 
                 150 
                 113.137 
                 22.104 
                 6.582 
                 1.00 
                 89.61 
                 C 
               
               
                 ATOM 
                 1212 
                 SD 
                 MET 
                 A 
                 150 
                 112.456 
                 23.348 
                 5.461 
                 1.00 
                 90.13 
                 S 
               
               
                 ATOM 
                 1213 
                 CE 
                 MET 
                 A 
                 150 
                 111.604 
                 24.446 
                 6.585 
                 1.00 
                 88.70 
                 C 
               
               
                 ATOM 
                 1214 
                 C 
                 MET 
                 A 
                 150 
                 116.472 
                 23.659 
                 7.818 
                 1.00 
                 88.28 
                 C 
               
               
                 ATOM 
                 1215 
                 O 
                 MET 
                 A 
                 150 
                 116.906 
                 23.054 
                 8.797 
                 1.00 
                 89.76 
                 O 
               
               
                 ATOM 
                 1216 
                 N 
                 PRO 
                 A 
                 151 
                 116.768 
                 24.949 
                 7.570 
                 1.00 
                 87.50 
                 N 
               
               
                 ATOM 
                 1217 
                 CA 
                 PRO 
                 A 
                 151 
                 117.634 
                 25.717 
                 8.464 
                 1.00 
                 88.75 
                 C 
               
               
                 ATOM 
                 1218 
                 CB 
                 PRO 
                 A 
                 151 
                 117.986 
                 26.949 
                 7.630 
                 1.00 
                 87.34 
                 C 
               
               
                 ATOM 
                 1219 
                 CG 
                 PRO 
                 A 
                 151 
                 116.809 
                 27.138 
                 6.747 
                 1.00 
                 87.38 
                 C 
               
               
                 ATOM 
                 1220 
                 CD 
                 PRO 
                 A 
                 151 
                 116.305 
                 25.760 
                 6.430 
                 1.00 
                 87.98 
                 C 
               
               
                 ATOM 
                 1221 
                 C 
                 PRO 
                 A 
                 151 
                 116.922 
                 26.131 
                 9.753 
                 1.00 
                 90.96 
                 C 
               
               
                 ATOM 
                 1222 
                 O 
                 PRO 
                 A 
                 151 
                 115.692 
                 26.071 
                 9.816 
                 1.00 
                 91.16 
                 O 
               
               
                 ATOM 
                 1223 
                 N 
                 PRO 
                 A 
                 152 
                 117.688 
                 26.558 
                 10.775 
                 1.00 
                 91.63 
                 N 
               
               
                 ATOM 
                 1224 
                 CA 
                 PRO 
                 A 
                 152 
                 117.083 
                 26.959 
                 12.038 
                 1.00 
                 91.53 
                 C 
               
               
                 ATOM 
                 1225 
                 CB 
                 PRO 
                 A 
                 152 
                 118.278 
                 27.020 
                 12.986 
                 1.00 
                 92.45 
                 C 
               
               
                 ATOM 
                 1226 
                 CG 
                 PRO 
                 A 
                 152 
                 119.412 
                 27.417 
                 12.110 
                 1.00 
                 92.47 
                 C 
               
               
                 ATOM 
                 1227 
                 CD 
                 PRO 
                 A 
                 152 
                 119.150 
                 26.757 
                 10.786 
                 1.00 
                 92.22 
                 C 
               
               
                 ATOM 
                 1228 
                 C 
                 PRO 
                 A 
                 152 
                 116.417 
                 28.324 
                 11.934 
                 1.00 
                 91.29 
                 C 
               
               
                 ATOM 
                 1229 
                 O 
                 PRO 
                 A 
                 152 
                 116.912 
                 29.203 
                 11.227 
                 1.00 
                 87.61 
                 O 
               
               
                 ATOM 
                 1230 
                 N 
                 CYS 
                 A 
                 153 
                 115.303 
                 28.490 
                 12.638 
                 1.00 
                 95.22 
                 N 
               
               
                 ATOM 
                 1231 
                 CA 
                 CYS 
                 A 
                 153 
                 114.562 
                 29.747 
                 12.624 
                 1.00 
                 100.58 
                 C 
               
               
                 ATOM 
                 1232 
                 CB 
                 CYS 
                 A 
                 153 
                 113.097 
                 29.506 
                 13.001 
                 1.00 
                 105.48 
                 C 
               
               
                 ATOM 
                 1233 
                 SG 
                 CYS 
                 A 
                 153 
                 112.131 
                 28.865 
                 11.616 
                 1.00 
                 110.80 
                 S 
               
               
                 ATOM 
                 1234 
                 C 
                 CYS 
                 A 
                 153 
                 115.197 
                 30.783 
                 13.546 
                 1.00 
                 99.11 
                 C 
               
               
                 ATOM 
                 1235 
                 O 
                 CYS 
                 A 
                 153 
                 115.962 
                 30.426 
                 14.440 
                 1.00 
                 100.03 
                 O 
               
               
                 ATOM 
                 1236 
                 N 
                 PRO 
                 A 
                 154 
                 114.883 
                 32.075 
                 13.328 
                 1.00 
                 99.89 
                 N 
               
               
                 ATOM 
                 1237 
                 CA 
                 PRO 
                 A 
                 154 
                 115.453 
                 33.146 
                 14.152 
                 1.00 
                 103.15 
                 C 
               
               
                 ATOM 
                 1238 
                 CB 
                 PRO 
                 A 
                 154 
                 114.838 
                 34.426 
                 13.556 
                 1.00 
                 102.45 
                 C 
               
               
                 ATOM 
                 1239 
                 CG 
                 PRO 
                 A 
                 154 
                 113.722 
                 33.979 
                 12.679 
                 1.00 
                 101.24 
                 C 
               
               
                 ATOM 
                 1240 
                 CD 
                 PRO 
                 A 
                 154 
                 114.096 
                 32.614 
                 12.206 
                 1.00 
                 101.08 
                 C 
               
               
                 ATOM 
                 1241 
                 C 
                 PRO 
                 A 
                 154 
                 115.136 
                 33.030 
                 15.655 
                 1.00 
                 106.30 
                 C 
               
               
                 ATOM 
                 1242 
                 O 
                 PRO 
                 A 
                 154 
                 114.291 
                 32.223 
                 16.043 
                 1.00 
                 103.59 
                 O 
               
               
                 ATOM 
                 1243 
                 N 
                 PRO 
                 A 
                 155 
                 115.820 
                 33.835 
                 16.494 
                 1.00 
                 109.83 
                 N 
               
               
                 ATOM 
                 1244 
                 CA 
                 PRO 
                 A 
                 155 
                 115.691 
                 33.817 
                 17.956 
                 1.00 
                 112.03 
                 C 
               
               
                 ATOM 
                 1245 
                 CB 
                 PRO 
                 A 
                 155 
                 116.332 
                 35.143 
                 18.369 
                 1.00 
                 114.04 
                 C 
               
               
                 ATOM 
                 1246 
                 CG 
                 PRO 
                 A 
                 155 
                 117.382 
                 35.371 
                 17.341 
                 1.00 
                 113.75 
                 C 
               
               
                 ATOM 
                 1247 
                 CD 
                 PRO 
                 A 
                 155 
                 116.841 
                 34.809 
                 16.056 
                 1.00 
                 111.64 
                 C 
               
               
                 ATOM 
                 1248 
                 C 
                 PRO 
                 A 
                 155 
                 114.265 
                 33.733 
                 18.509 
                 1.00 
                 111.44 
                 C 
               
               
                 ATOM 
                 1249 
                 O 
                 PRO 
                 A 
                 155 
                 114.016 
                 32.954 
                 19.434 
                 1.00 
                 112.99 
                 O 
               
               
                 ATOM 
                 1250 
                 N 
                 GLY 
                 A 
                 156 
                 113.345 
                 34.518 
                 17.951 
                 1.00 
                 108.40 
                 N 
               
               
                 ATOM 
                 1251 
                 CA 
                 GLY 
                 A 
                 156 
                 111.954 
                 34.533 
                 18.417 
                 1.00 
                 107.86 
                 C 
               
               
                 ATOM 
                 1252 
                 C 
                 GLY 
                 A 
                 156 
                 111.032 
                 33.536 
                 17.729 
                 1.00 
                 106.15 
                 C 
               
               
                 ATOM 
                 1253 
                 O 
                 GLY 
                 A 
                 156 
                 109.811 
                 33.688 
                 17.773 
                 1.00 
                 101.23 
                 O 
               
               
                 ATOM 
                 1254 
                 N 
                 GLY 
                 A 
                 157 
                 111.609 
                 32.511 
                 17.105 
                 1.00 
                 106.69 
                 N 
               
               
                 ATOM 
                 1255 
                 CA 
                 GLY 
                 A 
                 157 
                 110.837 
                 31.524 
                 16.355 
                 1.00 
                 104.57 
                 C 
               
               
                 ATOM 
                 1256 
                 C 
                 GLY 
                 A 
                 157 
                 110.410 
                 32.056 
                 14.998 
                 1.00 
                 101.90 
                 C 
               
               
                 ATOM 
                 1257 
                 O 
                 GLY 
                 A 
                 157 
                 110.762 
                 33.174 
                 14.618 
                 1.00 
                 104.11 
                 O 
               
               
                 ATOM 
                 1258 
                 N 
                 CYS 
                 A 
                 158 
                 109.652 
                 31.247 
                 14.266 
                 1.00 
                 98.35 
                 N 
               
               
                 ATOM 
                 1259 
                 CA 
                 CYS 
                 A 
                 158 
                 109.128 
                 31.629 
                 12.955 
                 1.00 
                 98.02 
                 C 
               
               
                 ATOM 
                 1260 
                 CB 
                 CYS 
                 A 
                 158 
                 109.898 
                 30.915 
                 11.840 
                 1.00 
                 99.92 
                 C 
               
               
                 ATOM 
                 1261 
                 SG 
                 CYS 
                 A 
                 158 
                 110.210 
                 29.171 
                 12.180 
                 1.00 
                 111.88 
                 S 
               
               
                 ATOM 
                 1262 
                 C 
                 CYS 
                 A 
                 158 
                 107.637 
                 31.313 
                 12.888 
                 1.00 
                 93.44 
                 C 
               
               
                 ATOM 
                 1263 
                 O 
                 CYS 
                 A 
                 158 
                 107.072 
                 30.765 
                 13.837 
                 1.00 
                 94.72 
                 O 
               
               
                 ATOM 
                 1264 
                 N 
                 HIS 
                 A 
                 159 
                 107.001 
                 31.678 
                 11.779 
                 1.00 
                 89.00 
                 N 
               
               
                 ATOM 
                 1265 
                 CA 
                 HIS 
                 A 
                 159 
                 105.567 
                 31.461 
                 11.600 
                 1.00 
                 86.06 
                 C 
               
               
                 ATOM 
                 1266 
                 CB 
                 HIS 
                 A 
                 159 
                 104.862 
                 32.797 
                 11.384 
                 1.00 
                 86.11 
                 C 
               
               
                 ATOM 
                 1267 
                 CG 
                 HIS 
                 A 
                 159 
                 104.714 
                 33.602 
                 12.634 
                 1.00 
                 85.86 
                 C 
               
               
                 ATOM 
                 1268 
                 ND1 
                 HIS 
                 A 
                 159 
                 105.771 
                 34.260 
                 13.224 
                 1.00 
                 85.50 
                 N 
               
               
                 ATOM 
                 1269 
                 CE1 
                 HIS 
                 A 
                 159 
                 105.349 
                 34.875 
                 14.314 
                 1.00 
                 87.12 
                 C 
               
               
                 ATOM 
                 1270 
                 NE2 
                 HIS 
                 A 
                 159 
                 104.056 
                 34.642 
                 14.451 
                 1.00 
                 85.96 
                 N 
               
               
                 ATOM 
                 1271 
                 CD2 
                 HIS 
                 A 
                 159 
                 103.634 
                 33.850 
                 13.412 
                 1.00 
                 86.34 
                 C 
               
               
                 ATOM 
                 1272 
                 C 
                 HIS 
                 A 
                 159 
                 105.258 
                 30.514 
                 10.447 
                 1.00 
                 83.23 
                 C 
               
               
                 ATOM 
                 1273 
                 O 
                 HIS 
                 A 
                 159 
                 105.976 
                 30.474 
                 9.448 
                 1.00 
                 81.54 
                 O 
               
               
                 ATOM 
                 1274 
                 N 
                 CYS 
                 A 
                 160 
                 104.185 
                 29.746 
                 10.617 
                 1.00 
                 80.95 
                 N 
               
               
                 ATOM 
                 1275 
                 CA 
                 CYS 
                 A 
                 160 
                 103.723 
                 28.792 
                 9.620 
                 1.00 
                 80.06 
                 C 
               
               
                 ATOM 
                 1276 
                 CB 
                 CYS 
                 A 
                 160 
                 103.953 
                 27.364 
                 10.107 
                 1.00 
                 82.18 
                 C 
               
               
                 ATOM 
                 1277 
                 SG 
                 CYS 
                 A 
                 160 
                 105.680 
                 26.861 
                 10.200 
                 1.00 
                 88.40 
                 S 
               
               
                 ATOM 
                 1278 
                 C 
                 CYS 
                 A 
                 160 
                 102.240 
                 28.985 
                 9.361 
                 1.00 
                 78.26 
                 C 
               
               
                 ATOM 
                 1279 
                 O 
                 CYS 
                 A 
                 160 
                 101.560 
                 29.715 
                 10.086 
                 1.00 
                 76.85 
                 O 
               
               
                 ATOM 
                 1280 
                 N 
                 ALA 
                 A 
                 161 
                 101.743 
                 28.316 
                 8.325 
                 1.00 
                 76.08 
                 N 
               
               
                 ATOM 
                 1281 
                 CA 
                 ALA 
                 A 
                 161 
                 100.328 
                 28.373 
                 7.982 
                 1.00 
                 73.79 
                 C 
               
               
                 ATOM 
                 1282 
                 CB 
                 ALA 
                 A 
                 161 
                 100.049 
                 29.573 
                 7.094 
                 1.00 
                 73.37 
                 C 
               
               
                 ATOM 
                 1283 
                 C 
                 ALA 
                 A 
                 161 
                 99.888 
                 27.088 
                 7.295 
                 1.00 
                 71.21 
                 C 
               
               
                 ATOM 
                 1284 
                 O 
                 ALA 
                 A 
                 161 
                 100.631 
                 26.515 
                 6.500 
                 1.00 
                 72.15 
                 O 
               
               
                 ATOM 
                 1285 
                 N 
                 TRP 
                 A 
                 162 
                 98.683 
                 26.637 
                 7.625 
                 1.00 
                 69.66 
                 N 
               
               
                 ATOM 
                 1286 
                 CA 
                 TRP 
                 A 
                 162 
                 98.103 
                 25.446 
                 7.022 
                 1.00 
                 68.18 
                 C 
               
               
                 ATOM 
                 1287 
                 CB 
                 TRP 
                 A 
                 162 
                 97.434 
                 24.575 
                 8.083 
                 1.00 
                 66.71 
                 C 
               
               
                 ATOM 
                 1288 
                 CG 
                 TRP 
                 A 
                 162 
                 96.645 
                 23.429 
                 7.522 
                 1.00 
                 64.24 
                 C 
               
               
                 ATOM 
                 1289 
                 CD1 
                 TRP 
                 A 
                 162 
                 97.124 
                 22.215 
                 7.134 
                 1.00 
                 63.87 
                 C 
               
               
                 ATOM 
                 1290 
                 NE1 
                 TRP 
                 A 
                 162 
                 96.099 
                 21.421 
                 6.686 
                 1.00 
                 62.98 
                 N 
               
               
                 ATOM 
                 1291 
                 CE2 
                 TRP 
                 A 
                 162 
                 94.926 
                 22.119 
                 6.779 
                 1.00 
                 62.55 
                 C 
               
               
                 ATOM 
                 1292 
                 CD2 
                 TRP 
                 A 
                 162 
                 95.232 
                 23.390 
                 7.304 
                 1.00 
                 62.40 
                 C 
               
               
                 ATOM 
                 1293 
                 CE3 
                 TRP 
                 A 
                 162 
                 94.194 
                 24.305 
                 7.505 
                 1.00 
                 63.45 
                 C 
               
               
                 ATOM 
                 1294 
                 CZ3 
                 TRP 
                 A 
                 162 
                 92.898 
                 23.927 
                 7.176 
                 1.00 
                 64.28 
                 C 
               
               
                 ATOM 
                 1295 
                 CH2 
                 TRP 
                 A 
                 162 
                 92.626 
                 22.655 
                 6.651 
                 1.00 
                 64.06 
                 C 
               
               
                 ATOM 
                 1296 
                 CZ2 
                 TRP 
                 A 
                 162 
                 93.625 
                 21.739 
                 6.448 
                 1.00 
                 63.81 
                 C 
               
               
                 ATOM 
                 1297 
                 C 
                 TRP 
                 A 
                 162 
                 97.083 
                 25.886 
                 5.988 
                 1.00 
                 67.79 
                 C 
               
               
                 ATOM 
                 1298 
                 O 
                 TRP 
                 A 
                 162 
                 96.149 
                 26.617 
                 6.309 
                 1.00 
                 67.02 
                 O 
               
               
                 ATOM 
                 1299 
                 N 
                 PHE 
                 A 
                 163 
                 97.266 
                 25.439 
                 4.750 
                 1.00 
                 67.99 
                 N 
               
               
                 ATOM 
                 1300 
                 CA 
                 PHE 
                 A 
                 163 
                 96.366 
                 25.793 
                 3.657 
                 1.00 
                 65.65 
                 C 
               
               
                 ATOM 
                 1301 
                 CB 
                 PHE 
                 A 
                 163 
                 97.140 
                 26.477 
                 2.538 
                 1.00 
                 62.67 
                 C 
               
               
                 ATOM 
                 1302 
                 CG 
                 PHE 
                 A 
                 163 
                 97.753 
                 27.784 
                 2.935 
                 1.00 
                 59.96 
                 C 
               
               
                 ATOM 
                 1303 
                 CD1 
                 PHE 
                 A 
                 163 
                 99.060 
                 27.843 
                 3.393 
                 1.00 
                 57.85 
                 C 
               
               
                 ATOM 
                 1304 
                 CE1 
                 PHE 
                 A 
                 163 
                 99.628 
                 29.055 
                 3.745 
                 1.00 
                 58.02 
                 C 
               
               
                 ATOM 
                 1305 
                 CZ 
                 PHE 
                 A 
                 163 
                 98.889 
                 30.224 
                 3.644 
                 1.00 
                 58.37 
                 C 
               
               
                 ATOM 
                 1306 
                 CE2 
                 PHE 
                 A 
                 163 
                 97.584 
                 30.177 
                 3.188 
                 1.00 
                 58.49 
                 C 
               
               
                 ATOM 
                 1307 
                 CD2 
                 PHE 
                 A 
                 163 
                 97.023 
                 28.961 
                 2.836 
                 1.00 
                 59.66 
                 C 
               
               
                 ATOM 
                 1308 
                 C 
                 PHE 
                 A 
                 163 
                 95.669 
                 24.561 
                 3.102 
                 1.00 
                 65.65 
                 C 
               
               
                 ATOM 
                 1309 
                 O 
                 PHE 
                 A 
                 163 
                 96.204 
                 23.462 
                 3.175 
                 1.00 
                 64.46 
                 O 
               
               
                 ATOM 
                 1310 
                 N 
                 TRP 
                 A 
                 164 
                 94.484 
                 24.762 
                 2.530 
                 1.00 
                 66.84 
                 N 
               
               
                 ATOM 
                 1311 
                 CA 
                 TRP 
                 A 
                 164 
                 93.709 
                 23.672 
                 1.948 
                 1.00 
                 66.24 
                 C 
               
               
                 ATOM 
                 1312 
                 CB 
                 TRP 
                 A 
                 164 
                 93.004 
                 22.883 
                 3.057 
                 1.00 
                 66.14 
                 C 
               
               
                 ATOM 
                 1313 
                 CG 
                 TRP 
                 A 
                 164 
                 92.024 
                 21.853 
                 2.559 
                 1.00 
                 64.96 
                 C 
               
               
                 ATOM 
                 1314 
                 CD1 
                 TRP 
                 A 
                 164 
                 92.256 
                 20.891 
                 1.626 
                 1.00 
                 64.45 
                 C 
               
               
                 ATOM 
                 1315 
                 NE1 
                 TRP 
                 A 
                 164 
                 91.129 
                 20.124 
                 1.444 
                 1.00 
                 64.11 
                 N 
               
               
                 ATOM 
                 1316 
                 CE2 
                 TRP 
                 A 
                 164 
                 90.145 
                 20.573 
                 2.282 
                 1.00 
                 62.02 
                 C 
               
               
                 ATOM 
                 1317 
                 CD2 
                 TRP 
                 A 
                 164 
                 90.674 
                 21.661 
                 3.006 
                 1.00 
                 64.79 
                 C 
               
               
                 ATOM 
                 1318 
                 CE3 
                 TRP 
                 A 
                 164 
                 89.861 
                 22.304 
                 3.948 
                 1.00 
                 66.51 
                 C 
               
               
                 ATOM 
                 1319 
                 CZ3 
                 TRP 
                 A 
                 164 
                 88.559 
                 21.847 
                 4.128 
                 1.00 
                 64.78 
                 C 
               
               
                 ATOM 
                 1320 
                 CH2 
                 TRP 
                 A 
                 164 
                 88.065 
                 20.761 
                 3.389 
                 1.00 
                 61.88 
                 C 
               
               
                 ATOM 
                 1321 
                 CZ2 
                 TRP 
                 A 
                 164 
                 88.842 
                 20.112 
                 2.467 
                 1.00 
                 60.20 
                 C 
               
               
                 ATOM 
                 1322 
                 C 
                 TRP 
                 A 
                 164 
                 92.684 
                 24.174 
                 0.937 
                 1.00 
                 65.82 
                 C 
               
               
                 ATOM 
                 1323 
                 O 
                 TRP 
                 A 
                 164 
                 91.957 
                 25.128 
                 1.202 
                 1.00 
                 65.09 
                 O 
               
               
                 ATOM 
                 1324 
                 N 
                 ILE 
                 A 
                 165 
                 92.654 
                 23.531 
                 −0.227 
                 1.00 
                 68.37 
                 N 
               
               
                 ATOM 
                 1325 
                 CA 
                 ILE 
                 A 
                 165 
                 91.652 
                 23.797 
                 −1.261 
                 1.00 
                 68.83 
                 C 
               
               
                 ATOM 
                 1326 
                 CB 
                 ILE 
                 A 
                 165 
                 92.247 
                 24.510 
                 −2.490 
                 1.00 
                 67.90 
                 C 
               
               
                 ATOM 
                 1327 
                 CG1 
                 ILE 
                 A 
                 165 
                 92.757 
                 25.897 
                 −2.091 
                 1.00 
                 67.98 
                 C 
               
               
                 ATOM 
                 1328 
                 CD1 
                 ILE 
                 A 
                 165 
                 93.456 
                 26.654 
                 −3.199 
                 1.00 
                 69.23 
                 C 
               
               
                 ATOM 
                 1329 
                 CG2 
                 ILE 
                 A 
                 165 
                 91.195 
                 24.624 
                 −3.588 
                 1.00 
                 69.24 
                 C 
               
               
                 ATOM 
                 1330 
                 C 
                 ILE 
                 A 
                 165 
                 91.067 
                 22.451 
                 −1.664 
                 1.00 
                 68.08 
                 C 
               
               
                 ATOM 
                 1331 
                 O 
                 ILE 
                 A 
                 165 
                 91.808 
                 21.515 
                 −1.962 
                 1.00 
                 69.04 
                 O 
               
               
                 ATOM 
                 1332 
                 N 
                 HIS 
                 A 
                 166 
                 89.742 
                 22.366 
                 −1.682 
                 1.00 
                 68.83 
                 N 
               
               
                 ATOM 
                 1333 
                 CA 
                 HIS 
                 A 
                 166 
                 89.053 
                 21.102 
                 −1.927 
                 1.00 
                 71.85 
                 C 
               
               
                 ATOM 
                 1334 
                 CB 
                 HIS 
                 A 
                 166 
                 87.972 
                 20.887 
                 −0.864 
                 1.00 
                 71.51 
                 C 
               
               
                 ATOM 
                 1335 
                 CG 
                 HIS 
                 A 
                 166 
                 86.856 
                 21.878 
                 −0.925 
                 1.00 
                 72.05 
                 C 
               
               
                 ATOM 
                 1336 
                 ND1 
                 HIS 
                 A 
                 166 
                 85.731 
                 21.680 
                 −1.693 
                 1.00 
                 75.81 
                 N 
               
               
                 ATOM 
                 1337 
                 CE1 
                 HIS 
                 A 
                 166 
                 84.918 
                 22.711 
                 −1.555 
                 1.00 
                 76.33 
                 C 
               
               
                 ATOM 
                 1338 
                 NE2 
                 HIS 
                 A 
                 166 
                 85.478 
                 23.574 
                 −0.727 
                 1.00 
                 75.99 
                 N 
               
               
                 ATOM 
                 1339 
                 CD2 
                 HIS 
                 A 
                 166 
                 86.693 
                 23.077 
                 −0.320 
                 1.00 
                 74.28 
                 C 
               
               
                 ATOM 
                 1340 
                 C 
                 HIS 
                 A 
                 166 
                 88.446 
                 21.000 
                 −3.331 
                 1.00 
                 73.81 
                 C 
               
               
                 ATOM 
                 1341 
                 O 
                 HIS 
                 A 
                 166 
                 88.442 
                 21.962 
                 −4.096 
                 1.00 
                 72.40 
                 O 
               
               
                 ATOM 
                 1342 
                 N 
                 SER 
                 A 
                 167 
                 87.926 
                 19.817 
                 −3.644 
                 1.00 
                 75.65 
                 N 
               
               
                 ATOM 
                 1343 
                 CA 
                 SER 
                 A 
                 167 
                 87.361 
                 19.532 
                 −4.953 
                 1.00 
                 78.55 
                 C 
               
               
                 ATOM 
                 1344 
                 CB 
                 SER 
                 A 
                 167 
                 87.006 
                 18.047 
                 −5.042 
                 1.00 
                 82.08 
                 C 
               
               
                 ATOM 
                 1345 
                 OG 
                 SER 
                 A 
                 167 
                 86.547 
                 17.699 
                 −6.338 
                 1.00 
                 86.01 
                 O 
               
               
                 ATOM 
                 1346 
                 C 
                 SER 
                 A 
                 167 
                 86.119 
                 20.376 
                 −5.238 
                 1.00 
                 78.52 
                 C 
               
               
                 ATOM 
                 1347 
                 O 
                 SER 
                 A 
                 167 
                 85.413 
                 20.761 
                 −4.307 
                 1.00 
                 79.61 
                 O 
               
               
                 ATOM 
                 1348 
                 N 
                 PRO 
                 A 
                 168 
                 85.852 
                 20.677 
                 −6.526 
                 1.00 
                 78.75 
                 N 
               
               
                 ATOM 
                 1349 
                 CA 
                 PRO 
                 A 
                 168 
                 84.641 
                 21.425 
                 −6.881 
                 1.00 
                 78.88 
                 C 
               
               
                 ATOM 
                 1350 
                 CB 
                 PRO 
                 A 
                 168 
                 84.899 
                 21.874 
                 −8.326 
                 1.00 
                 78.02 
                 C 
               
               
                 ATOM 
                 1351 
                 CG 
                 PRO 
                 A 
                 168 
                 86.326 
                 21.574 
                 −8.603 
                 1.00 
                 78.49 
                 C 
               
               
                 ATOM 
                 1352 
                 CD 
                 PRO 
                 A 
                 168 
                 86.703 
                 20.447 
                 −7.704 
                 1.00 
                 78.14 
                 C 
               
               
                 ATOM 
                 1353 
                 C 
                 PRO 
                 A 
                 168 
                 83.367 
                 20.588 
                 −6.835 
                 1.00 
                 80.35 
                 C 
               
               
                 ATOM 
                 1354 
                 O 
                 PRO 
                 A 
                 168 
                 82.273 
                 21.146 
                 −6.742 
                 1.00 
                 81.61 
                 O 
               
               
                 ATOM 
                 1355 
                 N 
                 ASP 
                 A 
                 169 
                 83.510 
                 19.266 
                 −6.896 
                 1.00 
                 80.49 
                 N 
               
               
                 ATOM 
                 1356 
                 CA 
                 ASP 
                 A 
                 169 
                 82.354 
                 18.370 
                 −6.936 
                 1.00 
                 82.01 
                 C 
               
               
                 ATOM 
                 1357 
                 CB 
                 ASP 
                 A 
                 169 
                 82.756 
                 17.006 
                 −7.512 
                 1.00 
                 84.94 
                 C 
               
               
                 ATOM 
                 1358 
                 CG 
                 ASP 
                 A 
                 169 
                 83.697 
                 16.240 
                 −6.606 
                 1.00 
                 87.76 
                 C 
               
               
                 ATOM 
                 1359 
                 OD1 
                 ASP 
                 A 
                 169 
                 84.189 
                 16.833 
                 −5.623 
                 1.00 
                 92.11 
                 O 
               
               
                 ATOM 
                 1360 
                 OD2 
                 ASP 
                 A 
                 169 
                 83.948 
                 15.046 
                 −6.877 
                 1.00 
                 90.58 
                 O 
               
               
                 ATOM 
                 1361 
                 C 
                 ASP 
                 A 
                 169 
                 81.649 
                 18.172 
                 −5.591 
                 1.00 
                 80.62 
                 C 
               
               
                 ATOM 
                 1362 
                 O 
                 ASP 
                 A 
                 169 
                 80.693 
                 17.404 
                 −5.515 
                 1.00 
                 80.75 
                 O 
               
               
                 ATOM 
                 1363 
                 N 
                 SER 
                 A 
                 170 
                 82.113 
                 18.839 
                 −4.536 
                 1.00 
                 81.20 
                 N 
               
               
                 ATOM 
                 1364 
                 CA 
                 SER 
                 A 
                 170 
                 81.455 
                 18.742 
                 −3.232 
                 1.00 
                 83.20 
                 C 
               
               
                 ATOM 
                 1365 
                 CB 
                 SER 
                 A 
                 170 
                 82.153 
                 17.712 
                 −2.346 
                 1.00 
                 82.93 
                 C 
               
               
                 ATOM 
                 1366 
                 OG 
                 SER 
                 A 
                 170 
                 81.443 
                 17.534 
                 −1.132 
                 1.00 
                 81.13 
                 O 
               
               
                 ATOM 
                 1367 
                 C 
                 SER 
                 A 
                 170 
                 81.408 
                 20.090 
                 −2.522 
                 1.00 
                 83.08 
                 C 
               
               
                 ATOM 
                 1368 
                 O 
                 SER 
                 A 
                 170 
                 82.436 
                 20.610 
                 −2.093 
                 1.00 
                 82.18 
                 O 
               
               
                 ATOM 
                 1369 
                 N 
                 GLY 
                 A 
                 171 
                 80.206 
                 20.652 
                 −2.424 
                 1.00 
                 84.35 
                 N 
               
               
                 ATOM 
                 1370 
                 CA 
                 GLY 
                 A 
                 171 
                 79.982 
                 21.907 
                 −1.718 
                 1.00 
                 86.21 
                 C 
               
               
                 ATOM 
                 1371 
                 C 
                 GLY 
                 A 
                 171 
                 80.536 
                 23.145 
                 −2.399 
                 1.00 
                 85.87 
                 C 
               
               
                 ATOM 
                 1372 
                 O 
                 GLY 
                 A 
                 171 
                 81.128 
                 23.072 
                 −3.480 
                 1.00 
                 85.11 
                 O 
               
               
                 ATOM 
                 1373 
                 N 
                 GLY 
                 A 
                 172 
                 80.336 
                 24.287 
                 −1.745 
                 1.00 
                 86.38 
                 N 
               
               
                 ATOM 
                 1374 
                 CA 
                 GLY 
                 A 
                 172 
                 80.805 
                 25.574 
                 −2.247 
                 1.00 
                 84.86 
                 C 
               
               
                 ATOM 
                 1375 
                 C 
                 GLY 
                 A 
                 172 
                 82.315 
                 25.662 
                 −2.207 
                 1.00 
                 81.45 
                 C 
               
               
                 ATOM 
                 1376 
                 O 
                 GLY 
                 A 
                 172 
                 82.956 
                 25.046 
                 −1.357 
                 1.00 
                 81.76 
                 O 
               
               
                 ATOM 
                 1377 
                 N 
                 GLU 
                 A 
                 173 
                 82.880 
                 26.442 
                 −3.120 
                 1.00 
                 79.46 
                 N 
               
               
                 ATOM 
                 1378 
                 CA 
                 GLU 
                 A 
                 173 
                 84.325 
                 26.534 
                 −3.252 
                 1.00 
                 80.95 
                 C 
               
               
                 ATOM 
                 1379 
                 CB 
                 GLU 
                 A 
                 173 
                 84.712 
                 26.590 
                 −4.732 
                 1.00 
                 82.70 
                 C 
               
               
                 ATOM 
                 1380 
                 CG 
                 GLU 
                 A 
                 173 
                 86.160 
                 26.234 
                 −5.000 
                 1.00 
                 83.57 
                 C 
               
               
                 ATOM 
                 1381 
                 CD 
                 GLU 
                 A 
                 173 
                 86.508 
                 24.803 
                 −4.637 
                 1.00 
                 86.05 
                 C 
               
               
                 ATOM 
                 1382 
                 OE1 
                 GLU 
                 A 
                 173 
                 85.904 
                 23.875 
                 −5.209 
                 1.00 
                 88.87 
                 O 
               
               
                 ATOM 
                 1383 
                 OE2 
                 GLU 
                 A 
                 173 
                 87.404 
                 24.608 
                 −3.790 
                 1.00 
                 89.20 
                 O 
               
               
                 ATOM 
                 1384 
                 C 
                 GLU 
                 A 
                 173 
                 84.884 
                 27.736 
                 −2.490 
                 1.00 
                 80.15 
                 C 
               
               
                 ATOM 
                 1385 
                 O 
                 GLU 
                 A 
                 173 
                 84.255 
                 28.792 
                 −2.417 
                 1.00 
                 77.51 
                 O 
               
               
                 ATOM 
                 1386 
                 N 
                 GLN 
                 A 
                 174 
                 86.078 
                 27.551 
                 −1.931 
                 1.00 
                 81.16 
                 N 
               
               
                 ATOM 
                 1387 
                 CA 
                 GLN 
                 A 
                 174 
                 86.731 
                 28.546 
                 −1.085 
                 1.00 
                 78.07 
                 C 
               
               
                 ATOM 
                 1388 
                 CB 
                 GLN 
                 A 
                 174 
                 85.999 
                 28.623 
                 0.256 
                 1.00 
                 76.04 
                 C 
               
               
                 ATOM 
                 1389 
                 CG 
                 GLN 
                 A 
                 174 
                 85.976 
                 27.296 
                 1.025 
                 1.00 
                 75.95 
                 C 
               
               
                 ATOM 
                 1390 
                 CD 
                 GLN 
                 A 
                 174 
                 84.636 
                 26.569 
                 1.067 
                 1.00 
                 75.19 
                 C 
               
               
                 ATOM 
                 1391 
                 OE1 
                 GLN 
                 A 
                 174 
                 84.600 
                 25.370 
                 1.346 
                 1.00 
                 78.72 
                 O 
               
               
                 ATOM 
                 1392 
                 NE2 
                 GLN 
                 A 
                 174 
                 83.537 
                 27.274 
                 0.816 
                 1.00 
                 75.03 
                 N 
               
               
                 ATOM 
                 1393 
                 C 
                 GLN 
                 A 
                 174 
                 88.182 
                 28.127 
                 −0.826 
                 1.00 
                 78.53 
                 C 
               
               
                 ATOM 
                 1394 
                 O 
                 GLN 
                 A 
                 174 
                 88.661 
                 27.152 
                 −1.412 
                 1.00 
                 83.04 
                 O 
               
               
                 ATOM 
                 1395 
                 N 
                 ILE 
                 A 
                 175 
                 88.873 
                 28.855 
                 0.051 
                 1.00 
                 76.75 
                 N 
               
               
                 ATOM 
                 1396 
                 CA 
                 ILE 
                 A 
                 175 
                 90.186 
                 28.425 
                 0.545 
                 1.00 
                 76.57 
                 C 
               
               
                 ATOM 
                 1397 
                 CB 
                 ILE 
                 A 
                 175 
                 91.345 
                 29.321 
                 0.057 
                 1.00 
                 76.05 
                 C 
               
               
                 ATOM 
                 1398 
                 CG1 
                 ILE 
                 A 
                 175 
                 91.363 
                 30.668 
                 0.788 
                 1.00 
                 75.36 
                 C 
               
               
                 ATOM 
                 1399 
                 CD1 
                 ILE 
                 A 
                 175 
                 92.640 
                 31.458 
                 0.585 
                 1.00 
                 74.21 
                 C 
               
               
                 ATOM 
                 1400 
                 CG2 
                 ILE 
                 A 
                 175 
                 91.255 
                 29.508 
                 −1.451 
                 1.00 
                 77.02 
                 C 
               
               
                 ATOM 
                 1401 
                 C 
                 ILE 
                 A 
                 175 
                 90.161 
                 28.378 
                 2.070 
                 1.00 
                 76.43 
                 C 
               
               
                 ATOM 
                 1402 
                 O 
                 ILE 
                 A 
                 175 
                 89.246 
                 28.910 
                 2.700 
                 1.00 
                 77.44 
                 O 
               
               
                 ATOM 
                 1403 
                 N 
                 TYR 
                 A 
                 176 
                 91.169 
                 27.731 
                 2.649 
                 1.00 
                 77.61 
                 N 
               
               
                 ATOM 
                 1404 
                 CA 
                 TYR 
                 A 
                 176 
                 91.292 
                 27.601 
                 4.101 
                 1.00 
                 77.05 
                 C 
               
               
                 ATOM 
                 1405 
                 CB 
                 TYR 
                 A 
                 176 
                 90.988 
                 26.167 
                 4.531 
                 1.00 
                 76.53 
                 C 
               
               
                 ATOM 
                 1406 
                 CG 
                 TYR 
                 A 
                 176 
                 89.539 
                 25.780 
                 4.364 
                 1.00 
                 76.89 
                 C 
               
               
                 ATOM 
                 1407 
                 CD1 
                 TYR 
                 A 
                 176 
                 89.042 
                 25.385 
                 3.130 
                 1.00 
                 77.36 
                 C 
               
               
                 ATOM 
                 1408 
                 CE1 
                 TYR 
                 A 
                 176 
                 87.714 
                 25.029 
                 2.976 
                 1.00 
                 77.51 
                 C 
               
               
                 ATOM 
                 1409 
                 CZ 
                 TYR 
                 A 
                 176 
                 86.865 
                 25.067 
                 4.063 
                 1.00 
                 76.94 
                 C 
               
               
                 ATOM 
                 1410 
                 OH 
                 TYR 
                 A 
                 176 
                 85.547 
                 24.719 
                 3.911 
                 1.00 
                 79.19 
                 O 
               
               
                 ATOM 
                 1411 
                 CE2 
                 TYR 
                 A 
                 176 
                 87.332 
                 25.456 
                 5.299 
                 1.00 
                 76.88 
                 C 
               
               
                 ATOM 
                 1412 
                 CD2 
                 TYR 
                 A 
                 176 
                 88.663 
                 25.809 
                 5.445 
                 1.00 
                 78.44 
                 C 
               
               
                 ATOM 
                 1413 
                 C 
                 TYR 
                 A 
                 176 
                 92.696 
                 27.988 
                 4.546 
                 1.00 
                 77.51 
                 C 
               
               
                 ATOM 
                 1414 
                 O 
                 TYR 
                 A 
                 176 
                 93.678 
                 27.575 
                 3.932 
                 1.00 
                 75.08 
                 O 
               
               
                 ATOM 
                 1415 
                 N 
                 MET 
                 A 
                 177 
                 92.784 
                 28.783 
                 5.610 
                 1.00 
                 80.01 
                 N 
               
               
                 ATOM 
                 1416 
                 CA 
                 MET 
                 A 
                 177 
                 94.074 
                 29.209 
                 6.154 
                 1.00 
                 77.80 
                 C 
               
               
                 ATOM 
                 1417 
                 CB 
                 MET 
                 A 
                 177 
                 94.488 
                 30.561 
                 5.577 
                 1.00 
                 78.47 
                 C 
               
               
                 ATOM 
                 1418 
                 CG 
                 MET 
                 A 
                 177 
                 95.844 
                 31.040 
                 6.070 
                 1.00 
                 77.88 
                 C 
               
               
                 ATOM 
                 1419 
                 SD 
                 MET 
                 A 
                 177 
                 96.289 
                 32.658 
                 5.429 
                 1.00 
                 79.52 
                 S 
               
               
                 ATOM 
                 1420 
                 CE 
                 MET 
                 A 
                 177 
                 97.914 
                 32.856 
                 6.160 
                 1.00 
                 79.52 
                 C 
               
               
                 ATOM 
                 1421 
                 C 
                 MET 
                 A 
                 177 
                 94.028 
                 29.309 
                 7.674 
                 1.00 
                 74.45 
                 C 
               
               
                 ATOM 
                 1422 
                 O 
                 MET 
                 A 
                 177 
                 93.098 
                 29.879 
                 8.239 
                 1.00 
                 73.78 
                 O 
               
               
                 ATOM 
                 1423 
                 N 
                 ASN 
                 A 
                 178 
                 95.050 
                 28.750 
                 8.317 
                 1.00 
                 72.63 
                 N 
               
               
                 ATOM 
                 1424 
                 CA 
                 ASN 
                 A 
                 178 
                 95.213 
                 28.808 
                 9.762 
                 1.00 
                 68.48 
                 C 
               
               
                 ATOM 
                 1425 
                 CB 
                 ASN 
                 A 
                 178 
                 94.727 
                 27.510 
                 10.410 
                 1.00 
                 68.50 
                 C 
               
               
                 ATOM 
                 1426 
                 CG 
                 ASN 
                 A 
                 178 
                 93.215 
                 27.425 
                 10.498 
                 1.00 
                 71.24 
                 C 
               
               
                 ATOM 
                 1427 
                 OD1 
                 ASN 
                 A 
                 178 
                 92.615 
                 26.424 
                 10.105 
                 1.00 
                 73.50 
                 O 
               
               
                 ATOM 
                 1428 
                 ND2 
                 ASN 
                 A 
                 178 
                 92.588 
                 28.473 
                 11.026 
                 1.00 
                 72.32 
                 N 
               
               
                 ATOM 
                 1429 
                 C 
                 ASN 
                 A 
                 178 
                 96.680 
                 29.037 
                 10.096 
                 1.00 
                 68.03 
                 C 
               
               
                 ATOM 
                 1430 
                 O 
                 ASN 
                 A 
                 178 
                 97.489 
                 28.114 
                 10.006 
                 1.00 
                 67.06 
                 O 
               
               
                 ATOM 
                 1431 
                 N 
                 GLY 
                 A 
                 179 
                 97.022 
                 30.268 
                 10.467 
                 1.00 
                 69.28 
                 N 
               
               
                 ATOM 
                 1432 
                 CA 
                 GLY 
                 A 
                 179 
                 98.395 
                 30.613 
                 10.837 
                 1.00 
                 72.01 
                 C 
               
               
                 ATOM 
                 1433 
                 C 
                 GLY 
                 A 
                 179 
                 98.720 
                 30.206 
                 12.266 
                 1.00 
                 75.63 
                 C 
               
               
                 ATOM 
                 1434 
                 O 
                 GLY 
                 A 
                 179 
                 97.822 
                 30.091 
                 13.108 
                 1.00 
                 76.00 
                 O 
               
               
                 ATOM 
                 1435 
                 N 
                 PHE 
                 A 
                 180 
                 100.002 
                 29.988 
                 12.547 
                 1.00 
                 76.09 
                 N 
               
               
                 ATOM 
                 1436 
                 CA 
                 PHE 
                 A 
                 180 
                 100.427 
                 29.579 
                 13.883 
                 1.00 
                 77.15 
                 C 
               
               
                 ATOM 
                 1437 
                 CB 
                 PHE 
                 A 
                 180 
                 100.021 
                 28.126 
                 14.143 
                 1.00 
                 78.41 
                 C 
               
               
                 ATOM 
                 1438 
                 CG 
                 PHE 
                 A 
                 180 
                 100.700 
                 27.136 
                 13.248 
                 1.00 
                 79.99 
                 C 
               
               
                 ATOM 
                 1439 
                 CD1 
                 PHE 
                 A 
                 180 
                 100.268 
                 26.952 
                 11.945 
                 1.00 
                 79.59 
                 C 
               
               
                 ATOM 
                 1440 
                 CE1 
                 PHE 
                 A 
                 180 
                 100.890 
                 26.037 
                 11.122 
                 1.00 
                 77.76 
                 C 
               
               
                 ATOM 
                 1441 
                 CZ 
                 PHE 
                 A 
                 180 
                 101.948 
                 25.286 
                 11.600 
                 1.00 
                 76.93 
                 C 
               
               
                 ATOM 
                 1442 
                 CE2 
                 PHE 
                 A 
                 180 
                 102.382 
                 25.456 
                 12.892 
                 1.00 
                 79.56 
                 C 
               
               
                 ATOM 
                 1443 
                 CD2 
                 PHE 
                 A 
                 180 
                 101.759 
                 26.375 
                 13.714 
                 1.00 
                 80.71 
                 C 
               
               
                 ATOM 
                 1444 
                 C 
                 PHE 
                 A 
                 180 
                 101.930 
                 29.735 
                 14.095 
                 1.00 
                 79.15 
                 C 
               
               
                 ATOM 
                 1445 
                 O 
                 PHE 
                 A 
                 180 
                 102.698 
                 29.831 
                 13.136 
                 1.00 
                 78.34 
                 O 
               
               
                 ATOM 
                 1446 
                 N 
                 GLN 
                 A 
                 181 
                 102.337 
                 29.759 
                 15.363 
                 1.00 
                 81.63 
                 N 
               
               
                 ATOM 
                 1447 
                 CA 
                 GLN 
                 A 
                 181 
                 103.748 
                 29.842 
                 15.723 
                 1.00 
                 82.49 
                 C 
               
               
                 ATOM 
                 1448 
                 CB 
                 GLN 
                 A 
                 181 
                 103.922 
                 30.335 
                 17.160 
                 1.00 
                 85.63 
                 C 
               
               
                 ATOM 
                 1449 
                 CG 
                 GLN 
                 A 
                 181 
                 103.581 
                 31.800 
                 17.376 
                 1.00 
                 87.98 
                 C 
               
               
                 ATOM 
                 1450 
                 CD 
                 GLN 
                 A 
                 181 
                 103.922 
                 32.281 
                 18.779 
                 1.00 
                 87.06 
                 C 
               
               
                 ATOM 
                 1451 
                 OE1 
                 GLN 
                 A 
                 181 
                 104.026 
                 31.487 
                 19.715 
                 1.00 
                 84.92 
                 O 
               
               
                 ATOM 
                 1452 
                 NE2 
                 GLN 
                 A 
                 181 
                 104.095 
                 33.590 
                 18.928 
                 1.00 
                 86.83 
                 N 
               
               
                 ATOM 
                 1453 
                 C 
                 GLN 
                 A 
                 181 
                 104.379 
                 28.467 
                 15.588 
                 1.00 
                 82.49 
                 C 
               
               
                 ATOM 
                 1454 
                 O 
                 GLN 
                 A 
                 181 
                 103.909 
                 27.505 
                 16.197 
                 1.00 
                 81.59 
                 O 
               
               
                 ATOM 
                 1455 
                 N 
                 CYS 
                 A 
                 182 
                 105.438 
                 28.377 
                 14.789 
                 1.00 
                 82.33 
                 N 
               
               
                 ATOM 
                 1456 
                 CA 
                 CYS 
                 A 
                 182 
                 106.152 
                 27.123 
                 14.597 
                 1.00 
                 82.80 
                 C 
               
               
                 ATOM 
                 1457 
                 CB 
                 CYS 
                 A 
                 182 
                 105.926 
                 26.586 
                 13.189 
                 1.00 
                 85.08 
                 C 
               
               
                 ATOM 
                 1458 
                 SG 
                 CYS 
                 A 
                 182 
                 106.333 
                 27.768 
                 11.889 
                 1.00 
                 88.27 
                 S 
               
               
                 ATOM 
                 1459 
                 C 
                 CYS 
                 A 
                 182 
                 107.642 
                 27.302 
                 14.822 
                 1.00 
                 82.53 
                 C 
               
               
                 ATOM 
                 1460 
                 O 
                 CYS 
                 A 
                 182 
                 108.136 
                 28.420 
                 14.963 
                 1.00 
                 80.43 
                 O 
               
               
                 ATOM 
                 1461 
                 N 
                 ASN 
                 A 
                 183 
                 108.350 
                 26.180 
                 14.858 
                 1.00 
                 83.98 
                 N 
               
               
                 ATOM 
                 1462 
                 CA 
                 ASN 
                 A 
                 183 
                 109.789 
                 26.178 
                 15.038 
                 1.00 
                 87.53 
                 C 
               
               
                 ATOM 
                 1463 
                 CB 
                 ASN 
                 A 
                 183 
                 110.127 
                 26.372 
                 16.515 
                 1.00 
                 94.35 
                 C 
               
               
                 ATOM 
                 1464 
                 CG 
                 ASN 
                 A 
                 183 
                 111.599 
                 26.621 
                 16.752 
                 1.00 
                 99.90 
                 C 
               
               
                 ATOM 
                 1465 
                 OD1 
                 ASN 
                 A 
                 183 
                 112.340 
                 27.000 
                 15.837 
                 1.00 
                 102.98 
                 O 
               
               
                 ATOM 
                 1466 
                 ND2 
                 ASN 
                 A 
                 183 
                 112.035 
                 26.415 
                 17.987 
                 1.00 
                 102.09 
                 N 
               
               
                 ATOM 
                 1467 
                 C 
                 ASN 
                 A 
                 183 
                 110.364 
                 24.867 
                 14.518 
                 1.00 
                 86.07 
                 C 
               
               
                 ATOM 
                 1468 
                 O 
                 ASN 
                 A 
                 183 
                 109.675 
                 23.846 
                 14.509 
                 1.00 
                 84.50 
                 O 
               
               
                 ATOM 
                 1469 
                 N 
                 ILE 
                 A 
                 184 
                 111.621 
                 24.899 
                 14.084 
                 1.00 
                 85.52 
                 N 
               
               
                 ATOM 
                 1470 
                 CA 
                 ILE 
                 A 
                 184 
                 112.261 
                 23.724 
                 13.500 
                 1.00 
                 85.50 
                 C 
               
               
                 ATOM 
                 1471 
                 CB 
                 ILE 
                 A 
                 184 
                 112.902 
                 24.067 
                 12.145 
                 1.00 
                 86.78 
                 C 
               
               
                 ATOM 
                 1472 
                 CG1 
                 ILE 
                 A 
                 184 
                 111.855 
                 24.741 
                 11.257 
                 1.00 
                 88.90 
                 C 
               
               
                 ATOM 
                 1473 
                 CD1 
                 ILE 
                 A 
                 184 
                 112.291 
                 24.944 
                 9.829 
                 1.00 
                 91.71 
                 C 
               
               
                 ATOM 
                 1474 
                 CG2 
                 ILE 
                 A 
                 184 
                 113.462 
                 22.813 
                 11.477 
                 1.00 
                 86.77 
                 C 
               
               
                 ATOM 
                 1475 
                 C 
                 ILE 
                 A 
                 184 
                 113.305 
                 23.121 
                 14.431 
                 1.00 
                 85.05 
                 C 
               
               
                 ATOM 
                 1476 
                 O 
                 ILE 
                 A 
                 184 
                 114.204 
                 23.814 
                 14.906 
                 1.00 
                 87.23 
                 O 
               
               
                 ATOM 
                 1477 
                 N 
                 THR 
                 A 
                 185 
                 113.172 
                 21.819 
                 14.673 
                 1.00 
                 84.65 
                 N 
               
               
                 ATOM 
                 1478 
                 CA 
                 THR 
                 A 
                 185 
                 114.090 
                 21.070 
                 15.519 
                 1.00 
                 84.52 
                 C 
               
               
                 ATOM 
                 1479 
                 CB 
                 THR 
                 A 
                 185 
                 113.324 
                 20.290 
                 16.607 
                 1.00 
                 83.63 
                 C 
               
               
                 ATOM 
                 1480 
                 OG1 
                 THR 
                 A 
                 185 
                 112.565 
                 19.231 
                 16.010 
                 1.00 
                 82.31 
                 O 
               
               
                 ATOM 
                 1481 
                 CG2 
                 THR 
                 A 
                 185 
                 112.382 
                 21.212 
                 17.373 
                 1.00 
                 82.88 
                 C 
               
               
                 ATOM 
                 1482 
                 C 
                 THR 
                 A 
                 185 
                 114.884 
                 20.089 
                 14.660 
                 1.00 
                 87.43 
                 C 
               
               
                 ATOM 
                 1483 
                 O 
                 THR 
                 A 
                 185 
                 114.461 
                 19.731 
                 13.562 
                 1.00 
                 92.86 
                 O 
               
               
                 ATOM 
                 1484 
                 N 
                 GLY 
                 A 
                 186 
                 116.033 
                 19.654 
                 15.163 
                 1.00 
                 89.40 
                 N 
               
               
                 ATOM 
                 1485 
                 CA 
                 GLY 
                 A 
                 186 
                 116.885 
                 18.702 
                 14.449 
                 1.00 
                 89.10 
                 C 
               
               
                 ATOM 
                 1486 
                 C 
                 GLY 
                 A 
                 186 
                 117.567 
                 19.281 
                 13.222 
                 1.00 
                 87.83 
                 C 
               
               
                 ATOM 
                 1487 
                 O 
                 GLY 
                 A 
                 186 
                 117.929 
                 18.544 
                 12.304 
                 1.00 
                 86.14 
                 O 
               
               
                 ATOM 
                 1488 
                 N 
                 SER 
                 A 
                 187 
                 117.760 
                 20.599 
                 13.215 
                 1.00 
                 87.16 
                 N 
               
               
                 ATOM 
                 1489 
                 CA 
                 SER 
                 A 
                 187 
                 118.376 
                 21.288 
                 12.084 
                 1.00 
                 87.75 
                 C 
               
               
                 ATOM 
                 1490 
                 CB 
                 SER 
                 A 
                 187 
                 118.233 
                 22.803 
                 12.249 
                 1.00 
                 86.93 
                 C 
               
               
                 ATOM 
                 1491 
                 OG 
                 SER 
                 A 
                 187 
                 118.824 
                 23.495 
                 11.163 
                 1.00 
                 87.00 
                 O 
               
               
                 ATOM 
                 1492 
                 C 
                 SER 
                 A 
                 187 
                 119.852 
                 20.926 
                 11.941 
                 1.00 
                 88.80 
                 C 
               
               
                 ATOM 
                 1493 
                 O 
                 SER 
                 A 
                 187 
                 120.620 
                 21.057 
                 12.892 
                 1.00 
                 91.38 
                 O 
               
               
                 ATOM 
                 1494 
                 N 
                 THR 
                 A 
                 188 
                 120.234 
                 20.467 
                 10.750 
                 1.00 
                 91.89 
                 N 
               
               
                 ATOM 
                 1495 
                 CA 
                 THR 
                 A 
                 188 
                 121.626 
                 20.126 
                 10.444 
                 1.00 
                 93.80 
                 C 
               
               
                 ATOM 
                 1496 
                 CB 
                 THR 
                 A 
                 188 
                 121.803 
                 18.608 
                 10.225 
                 1.00 
                 94.36 
                 C 
               
               
                 ATOM 
                 1497 
                 OG1 
                 THR 
                 A 
                 188 
                 121.083 
                 18.199 
                 9.055 
                 1.00 
                 97.73 
                 O 
               
               
                 ATOM 
                 1498 
                 CG2 
                 THR 
                 A 
                 188 
                 121.299 
                 17.827 
                 11.429 
                 1.00 
                 95.01 
                 C 
               
               
                 ATOM 
                 1499 
                 C 
                 THR 
                 A 
                 188 
                 122.085 
                 20.876 
                 9.193 
                 1.00 
                 95.01 
                 C 
               
               
                 ATOM 
                 1500 
                 O 
                 THR 
                 A 
                 188 
                 122.790 
                 20.323 
                 8.349 
                 1.00 
                 94.25 
                 O 
               
               
                 ATOM 
                 1501 
                 N 
                 SER 
                 A 
                 189 
                 121.677 
                 22.139 
                 9.084 
                 1.00 
                 97.50 
                 N 
               
               
                 ATOM 
                 1502 
                 CA 
                 SER 
                 A 
                 189 
                 122.010 
                 22.974 
                 7.930 
                 1.00 
                 98.32 
                 C 
               
               
                 ATOM 
                 1503 
                 CB 
                 SER 
                 A 
                 189 
                 121.191 
                 22.547 
                 6.711 
                 1.00 
                 97.46 
                 C 
               
               
                 ATOM 
                 1504 
                 OG 
                 SER 
                 A 
                 189 
                 121.468 
                 23.375 
                 5.596 
                 1.00 
                 96.80 
                 O 
               
               
                 ATOM 
                 1505 
                 C 
                 SER 
                 A 
                 189 
                 121.746 
                 24.447 
                 8.228 
                 1.00 
                 100.26 
                 C 
               
               
                 ATOM 
                 1506 
                 O 
                 SER 
                 A 
                 189 
                 120.976 
                 24.773 
                 9.128 
                 1.00 
                 100.80 
                 O 
               
               
                 ATOM 
                 1507 
                 N 
                 HIS 
                 A 
                 190 
                 122.402 
                 25.327 
                 7.475 
                 1.00 
                 100.89 
                 N 
               
               
                 ATOM 
                 1508 
                 CA 
                 HIS 
                 A 
                 190 
                 122.232 
                 26.775 
                 7.622 
                 1.00 
                 101.15 
                 C 
               
               
                 ATOM 
                 1509 
                 CB 
                 HIS 
                 A 
                 190 
                 123.489 
                 27.394 
                 8.244 
                 1.00 
                 104.71 
                 C 
               
               
                 ATOM 
                 1510 
                 CG 
                 HIS 
                 A 
                 190 
                 123.642 
                 27.110 
                 9.705 
                 1.00 
                 109.21 
                 C 
               
               
                 ATOM 
                 1511 
                 ND1 
                 HIS 
                 A 
                 190 
                 124.242 
                 25.965 
                 10.184 
                 1.00 
                 110.75 
                 N 
               
               
                 ATOM 
                 1512 
                 CE1 
                 HIS 
                 A 
                 190 
                 124.233 
                 25.986 
                 11.505 
                 1.00 
                 112.14 
                 C 
               
               
                 ATOM 
                 1513 
                 NE2 
                 HIS 
                 A 
                 190 
                 123.651 
                 27.104 
                 11.900 
                 1.00 
                 113.10 
                 N 
               
               
                 ATOM 
                 1514 
                 CD2 
                 HIS 
                 A 
                 190 
                 123.272 
                 27.825 
                 10.794 
                 1.00 
                 111.06 
                 C 
               
               
                 ATOM 
                 1515 
                 C 
                 HIS 
                 A 
                 190 
                 121.908 
                 27.475 
                 6.301 
                 1.00 
                 98.77 
                 C 
               
               
                 ATOM 
                 1516 
                 O 
                 HIS 
                 A 
                 190 
                 121.777 
                 28.700 
                 6.269 
                 1.00 
                 99.11 
                 O 
               
               
                 ATOM 
                 1517 
                 N 
                 VAL 
                 A 
                 191 
                 121.765 
                 26.708 
                 5.222 
                 1.00 
                 96.73 
                 N 
               
               
                 ATOM 
                 1518 
                 CA 
                 VAL 
                 A 
                 191 
                 121.453 
                 27.279 
                 3.913 
                 1.00 
                 92.97 
                 C 
               
               
                 ATOM 
                 1519 
                 CB 
                 VAL 
                 A 
                 191 
                 121.734 
                 26.286 
                 2.765 
                 1.00 
                 93.24 
                 C 
               
               
                 ATOM 
                 1520 
                 CG1 
                 VAL 
                 A 
                 191 
                 121.399 
                 26.919 
                 1.420 
                 1.00 
                 94.47 
                 C 
               
               
                 ATOM 
                 1521 
                 CG2 
                 VAL 
                 A 
                 191 
                 123.188 
                 25.832 
                 2.791 
                 1.00 
                 92.73 
                 C 
               
               
                 ATOM 
                 1522 
                 C 
                 VAL 
                 A 
                 191 
                 119.975 
                 27.671 
                 3.907 
                 1.00 
                 89.35 
                 C 
               
               
                 ATOM 
                 1523 
                 O 
                 VAL 
                 A 
                 191 
                 119.106 
                 26.804 
                 4.023 
                 1.00 
                 88.41 
                 O 
               
               
                 ATOM 
                 1524 
                 N 
                 PRO 
                 A 
                 192 
                 119.685 
                 28.977 
                 3.763 
                 1.00 
                 85.73 
                 N 
               
               
                 ATOM 
                 1525 
                 CA 
                 PRO 
                 A 
                 192 
                 118.304 
                 29.454 
                 3.837 
                 1.00 
                 85.92 
                 C 
               
               
                 ATOM 
                 1526 
                 CB 
                 PRO 
                 A 
                 192 
                 118.465 
                 30.977 
                 3.882 
                 1.00 
                 85.56 
                 C 
               
               
                 ATOM 
                 1527 
                 CG 
                 PRO 
                 A 
                 192 
                 119.733 
                 31.239 
                 3.152 
                 1.00 
                 85.62 
                 C 
               
               
                 ATOM 
                 1528 
                 CD 
                 PRO 
                 A 
                 192 
                 120.625 
                 30.062 
                 3.424 
                 1.00 
                 85.73 
                 C 
               
               
                 ATOM 
                 1529 
                 C 
                 PRO 
                 A 
                 192 
                 117.431 
                 29.038 
                 2.650 
                 1.00 
                 87.68 
                 C 
               
               
                 ATOM 
                 1530 
                 O 
                 PRO 
                 A 
                 192 
                 117.916 
                 28.426 
                 1.694 
                 1.00 
                 87.51 
                 O 
               
               
                 ATOM 
                 1531 
                 N 
                 LEU 
                 A 
                 193 
                 116.145 
                 29.368 
                 2.734 
                 1.00 
                 88.68 
                 N 
               
               
                 ATOM 
                 1532 
                 CA 
                 LEU 
                 A 
                 193 
                 115.191 
                 29.059 
                 1.675 
                 1.00 
                 88.77 
                 C 
               
               
                 ATOM 
                 1533 
                 CB 
                 LEU 
                 A 
                 193 
                 113.762 
                 28.982 
                 2.228 
                 1.00 
                 89.66 
                 C 
               
               
                 ATOM 
                 1534 
                 CG 
                 LEU 
                 A 
                 193 
                 113.369 
                 27.730 
                 3.019 
                 1.00 
                 91.71 
                 C 
               
               
                 ATOM 
                 1535 
                 CD1 
                 LEU 
                 A 
                 193 
                 114.294 
                 27.487 
                 4.203 
                 1.00 
                 93.84 
                 C 
               
               
                 ATOM 
                 1536 
                 CD2 
                 LEU 
                 A 
                 193 
                 111.925 
                 27.843 
                 3.485 
                 1.00 
                 90.96 
                 C 
               
               
                 ATOM 
                 1537 
                 C 
                 LEU 
                 A 
                 193 
                 115.258 
                 30.117 
                 0.582 
                 1.00 
                 90.31 
                 C 
               
               
                 ATOM 
                 1538 
                 O 
                 LEU 
                 A 
                 193 
                 115.552 
                 31.282 
                 0.852 
                 1.00 
                 90.47 
                 O 
               
               
                 ATOM 
                 1539 
                 N 
                 ALA 
                 A 
                 194 
                 114.984 
                 29.701 
                 −0.651 
                 1.00 
                 91.88 
                 N 
               
               
                 ATOM 
                 1540 
                 CA 
                 ALA 
                 A 
                 194 
                 114.947 
                 30.620 
                 −1.785 
                 1.00 
                 92.62 
                 C 
               
               
                 ATOM 
                 1541 
                 CB 
                 ALA 
                 A 
                 194 
                 115.054 
                 29.851 
                 −3.092 
                 1.00 
                 94.08 
                 C 
               
               
                 ATOM 
                 1542 
                 C 
                 ALA 
                 A 
                 194 
                 113.647 
                 31.413 
                 −1.744 
                 1.00 
                 92.46 
                 C 
               
               
                 ATOM 
                 1543 
                 O 
                 ALA 
                 A 
                 194 
                 112.663 
                 30.965 
                 −1.151 
                 1.00 
                 92.11 
                 O 
               
               
                 ATOM 
                 1544 
                 N 
                 LYS 
                 A 
                 195 
                 113.645 
                 32.593 
                 −2.361 
                 1.00 
                 93.79 
                 N 
               
               
                 ATOM 
                 1545 
                 CA 
                 LYS 
                 A 
                 195 
                 112.437 
                 33.415 
                 −2.412 
                 1.00 
                 96.51 
                 C 
               
               
                 ATOM 
                 1546 
                 CB 
                 LYS 
                 A 
                 195 
                 112.718 
                 34.780 
                 −3.041 
                 1.00 
                 101.11 
                 C 
               
               
                 ATOM 
                 1547 
                 CG 
                 LYS 
                 A 
                 195 
                 113.591 
                 35.670 
                 −2.171 
                 1.00 
                 108.63 
                 C 
               
               
                 ATOM 
                 1548 
                 CD 
                 LYS 
                 A 
                 195 
                 113.770 
                 37.056 
                 −2.769 
                 1.00 
                 116.33 
                 C 
               
               
                 ATOM 
                 1549 
                 CE 
                 LYS 
                 A 
                 195 
                 114.626 
                 37.937 
                 −1.870 
                 1.00 
                 118.72 
                 C 
               
               
                 ATOM 
                 1550 
                 NZ 
                 LYS 
                 A 
                 195 
                 114.852 
                 39.289 
                 −2.453 
                 1.00 
                 120.76 
                 N 
               
               
                 ATOM 
                 1551 
                 C 
                 LYS 
                 A 
                 195 
                 111.364 
                 32.666 
                 −3.196 
                 1.00 
                 94.08 
                 C 
               
               
                 ATOM 
                 1552 
                 O 
                 LYS 
                 A 
                 195 
                 111.553 
                 32.383 
                 −4.380 
                 1.00 
                 94.57 
                 O 
               
               
                 ATOM 
                 1553 
                 N 
                 PRO 
                 A 
                 196 
                 110.239 
                 32.335 
                 −2.537 
                 1.00 
                 89.68 
                 N 
               
               
                 ATOM 
                 1554 
                 CA 
                 PRO 
                 A 
                 196 
                 109.214 
                 31.518 
                 −3.174 
                 1.00 
                 89.92 
                 C 
               
               
                 ATOM 
                 1555 
                 CB 
                 PRO 
                 A 
                 196 
                 108.264 
                 31.195 
                 −2.021 
                 1.00 
                 90.30 
                 C 
               
               
                 ATOM 
                 1556 
                 CG 
                 PRO 
                 A 
                 196 
                 108.366 
                 32.383 
                 −1 .137 
                 1.00 
                 89.69 
                 C 
               
               
                 ATOM 
                 1557 
                 CD 
                 PRO 
                 A 
                 196 
                 109.794 
                 32.837 
                 −1.224 
                 1.00 
                 89.48 
                 C 
               
               
                 ATOM 
                 1558 
                 C 
                 PRO 
                 A 
                 196 
                 108.480 
                 32.251 
                 −4.291 
                 1.00 
                 88.68 
                 C 
               
               
                 ATOM 
                 1559 
                 O 
                 PRO 
                 A 
                 196 
                 108.298 
                 33.467 
                 −4.217 
                 1.00 
                 84.56 
                 O 
               
               
                 ATOM 
                 1560 
                 N 
                 LYS 
                 A 
                 197 
                 108.062 
                 31.498 
                 −5.308 
                 1.00 
                 89.24 
                 N 
               
               
                 ATOM 
                 1561 
                 CA 
                 LYS 
                 A 
                 197 
                 107.406 
                 32.056 
                 −6.486 
                 1.00 
                 90.03 
                 C 
               
               
                 ATOM 
                 1562 
                 CB 
                 LYS 
                 A 
                 197 
                 108.300 
                 31.857 
                 −7.708 
                 1.00 
                 94.64 
                 C 
               
               
                 ATOM 
                 1563 
                 CG 
                 LYS 
                 A 
                 197 
                 109.639 
                 32.561 
                 −7.567 
                 1.00 
                 102.22 
                 C 
               
               
                 ATOM 
                 1564 
                 CD 
                 LYS 
                 A 
                 197 
                 110.545 
                 32.364 
                 −8.768 
                 1.00 
                 108.84 
                 C 
               
               
                 ATOM 
                 1565 
                 CE 
                 LYS 
                 A 
                 197 
                 111.819 
                 33.181 
                 −8.599 
                 1.00 
                 114.08 
                 C 
               
               
                 ATOM 
                 1566 
                 NZ 
                 LYS 
                 A 
                 197 
                 112.776 
                 33.008 
                 −9.726 
                 1.00 
                 117.94 
                 N 
               
               
                 ATOM 
                 1567 
                 C 
                 LYS 
                 A 
                 197 
                 106.035 
                 31.434 
                 −6.711 
                 1.00 
                 87.01 
                 C 
               
               
                 ATOM 
                 1568 
                 O 
                 LYS 
                 A 
                 197 
                 105.739 
                 30.359 
                 −6.192 
                 1.00 
                 86.28 
                 O 
               
               
                 ATOM 
                 1569 
                 N 
                 VAL 
                 A 
                 198 
                 105.205 
                 32.120 
                 −7.492 
                 1.00 
                 85.50 
                 N 
               
               
                 ATOM 
                 1570 
                 CA 
                 VAL 
                 A 
                 198 
                 103.827 
                 31.689 
                 −7.739 
                 1.00 
                 84.79 
                 C 
               
               
                 ATOM 
                 1571 
                 CB 
                 VAL 
                 A 
                 198 
                 103.047 
                 32.737 
                 −8.567 
                 1.00 
                 84.93 
                 C 
               
               
                 ATOM 
                 1572 
                 CG1 
                 VAL 
                 A 
                 198 
                 101.643 
                 32.239 
                 −8.896 
                 1.00 
                 84.34 
                 C 
               
               
                 ATOM 
                 1573 
                 CG2 
                 VAL 
                 A 
                 198 
                 102.983 
                 34.067 
                 −7.822 
                 1.00 
                 84.73 
                 C 
               
               
                 ATOM 
                 1574 
                 C 
                 VAL 
                 A 
                 198 
                 103.783 
                 30.337 
                 −8.452 
                 1.00 
                 83.78 
                 C 
               
               
                 ATOM 
                 1575 
                 O 
                 VAL 
                 A 
                 198 
                 104.502 
                 30.119 
                 −9.426 
                 1.00 
                 82.25 
                 O 
               
               
                 ATOM 
                 1576 
                 N 
                 ALA 
                 A 
                 199 
                 102.938 
                 29.438 
                 −7.952 
                 1.00 
                 85.82 
                 N 
               
               
                 ATOM 
                 1577 
                 CA 
                 ALA 
                 A 
                 199 
                 102.791 
                 28.103 
                 −8.529 
                 1.00 
                 87.01 
                 C 
               
               
                 ATOM 
                 1578 
                 CB 
                 ALA 
                 A 
                 199 
                 102.153 
                 27.159 
                 −7.521 
                 1.00 
                 87.79 
                 C 
               
               
                 ATOM 
                 1579 
                 C 
                 ALA 
                 A 
                 199 
                 101.950 
                 28.165 
                 −9.799 
                 1.00 
                 86.64 
                 C 
               
               
                 ATOM 
                 1580 
                 O 
                 ALA 
                 A 
                 199 
                 100.884 
                 28.778 
                 −9.811 
                 1.00 
                 85.61 
                 O 
               
               
                 ATOM 
                 1581 
                 N 
                 ARG 
                 A 
                 200 
                 102.434 
                 27.526 
                 −10.862 
                 1.00 
                 87.46 
                 N 
               
               
                 ATOM 
                 1582 
                 CA 
                 ARG 
                 A 
                 200 
                 101.745 
                 27.524 
                 −12.153 
                 1.00 
                 85.78 
                 C 
               
               
                 ATOM 
                 1583 
                 CB 
                 ARG 
                 A 
                 200 
                 102.754 
                 27.716 
                 −13.284 
                 1.00 
                 87.93 
                 C 
               
               
                 ATOM 
                 1584 
                 CG 
                 ARG 
                 A 
                 200 
                 103.507 
                 29.037 
                 −13.218 
                 1.00 
                 90.52 
                 C 
               
               
                 ATOM 
                 1585 
                 CD 
                 ARG 
                 A 
                 200 
                 104.596 
                 29.114 
                 −14.276 
                 1.00 
                 92.57 
                 C 
               
               
                 ATOM 
                 1586 
                 NE 
                 ARG 
                 A 
                 200 
                 104.039 
                 29.134 
                 −15.626 
                 1.00 
                 94.90 
                 N 
               
               
                 ATOM 
                 1587 
                 CZ 
                 ARG 
                 A 
                 200 
                 103.594 
                 30.223 
                 −16.251 
                 1.00 
                 97.54 
                 C 
               
               
                 ATOM 
                 1588 
                 NH1 
                 ARG 
                 A 
                 200 
                 103.104 
                 30.118 
                 −17.481 
                 1.00 
                 100.03 
                 N 
               
               
                 ATOM 
                 1589 
                 NH2 
                 ARG 
                 A 
                 200 
                 103.630 
                 31.416 
                 −15.663 
                 1.00 
                 98.92 
                 N 
               
               
                 ATOM 
                 1590 
                 C 
                 ARG 
                 A 
                 200 
                 100.978 
                 26.224 
                 −12.355 
                 1.00 
                 83.28 
                 C 
               
               
                 ATOM 
                 1591 
                 O 
                 ARG 
                 A 
                 200 
                 101.387 
                 25.176 
                 −11.855 
                 1.00 
                 84.83 
                 O 
               
               
                 ATOM 
                 1592 
                 N 
                 ARG 
                 A 
                 201 
                 99.866 
                 26.299 
                 −13.087 
                 1.00 
                 82.76 
                 N 
               
               
                 ATOM 
                 1593 
                 CA 
                 ARG 
                 A 
                 201 
                 99.032 
                 25.127 
                 −13.374 
                 1.00 
                 84.44 
                 C 
               
               
                 ATOM 
                 1594 
                 CB 
                 ARG 
                 A 
                 201 
                 97.675 
                 25.557 
                 −13.940 
                 1.00 
                 82.09 
                 C 
               
               
                 ATOM 
                 1595 
                 CG 
                 ARG 
                 A 
                 201 
                 96.632 
                 24.456 
                 −13.958 
                 1.00 
                 79.77 
                 C 
               
               
                 ATOM 
                 1596 
                 CD 
                 ARG 
                 A 
                 201 
                 95.331 
                 24.954 
                 −14.554 
                 1.00 
                 79.28 
                 C 
               
               
                 ATOM 
                 1597 
                 NE 
                 ARG 
                 A 
                 201 
                 94.242 
                 23.990 
                 −14.392 
                 1.00 
                 80.17 
                 N 
               
               
                 ATOM 
                 1598 
                 CZ 
                 ARG 
                 A 
                 201 
                 93.447 
                 23.899 
                 −13.323 
                 1.00 
                 79.41 
                 C 
               
               
                 ATOM 
                 1599 
                 NH1 
                 ARG 
                 A 
                 201 
                 92.485 
                 22.982 
                 −13.298 
                 1.00 
                 79.97 
                 N 
               
               
                 ATOM 
                 1600 
                 NH2 
                 ARG 
                 A 
                 201 
                 93.600 
                 24.707 
                 −12.279 
                 1.00 
                 79.24 
                 N 
               
               
                 ATOM 
                 1601 
                 C 
                 ARG 
                 A 
                 201 
                 99.786 
                 24.225 
                 −14.352 
                 1.00 
                 87.56 
                 C 
               
               
                 ATOM 
                 1602 
                 O 
                 ARG 
                 A 
                 201 
                 99.591 
                 24.278 
                 −15.563 
                 1.00 
                 85.14 
                 O 
               
               
                 ATOM 
                 1603 
                 N 
                 CYS 
                 A 
                 202 
                 100.640 
                 23.380 
                 −13.792 
                 1.00 
                 94.65 
                 N 
               
               
                 ATOM 
                 1604 
                 CA 
                 CYS 
                 A 
                 202 
                 101.609 
                 22.608 
                 −14.559 
                 1.00 
                 95.70 
                 C 
               
               
                 ATOM 
                 1605 
                 CB 
                 CYS 
                 A 
                 202 
                 102.867 
                 22.449 
                 −13.708 
                 1.00 
                 99.41 
                 C 
               
               
                 ATOM 
                 1606 
                 SG 
                 CYS 
                 A 
                 202 
                 104.213 
                 21.618 
                 −14.557 
                 1.00 
                 111.34 
                 S 
               
               
                 ATOM 
                 1607 
                 C 
                 CYS 
                 A 
                 202 
                 101.142 
                 21.228 
                 −15.009 
                 1.00 
                 93.03 
                 C 
               
               
                 ATOM 
                 1608 
                 O 
                 CYS 
                 A 
                 202 
                 101.151 
                 20.921 
                 −16.198 
                 1.00 
                 90.38 
                 O 
               
               
                 ATOM 
                 1609 
                 N 
                 GLY 
                 A 
                 203 
                 100.750 
                 20.400 
                 −14.046 
                 1.00 
                 94.84 
                 N 
               
               
                 ATOM 
                 1610 
                 CA 
                 GLY 
                 A 
                 203 
                 100.396 
                 19.003 
                 −14.295 
                 1.00 
                 95.40 
                 C 
               
               
                 ATOM 
                 1611 
                 C 
                 GLY 
                 A 
                 203 
                 99.189 
                 18.741 
                 −15.174 
                 1.00 
                 94.49 
                 C 
               
               
                 ATOM 
                 1612 
                 O 
                 GLY 
                 A 
                 203 
                 98.573 
                 19.662 
                 −15.708 
                 1.00 
                 95.78 
                 O 
               
               
                 ATOM 
                 1613 
                 N 
                 ALA 
                 A 
                 204 
                 98.860 
                 17.462 
                 −15.312 
                 1.00 
                 93.19 
                 N 
               
               
                 ATOM 
                 1614 
                 CA 
                 ALA 
                 A 
                 204 
                 97.767 
                 17.027 
                 −16.167 
                 1.00 
                 94.27 
                 C 
               
               
                 ATOM 
                 1615 
                 CB 
                 ALA 
                 A 
                 204 
                 98.058 
                 15.637 
                 −16.707 
                 1.00 
                 94.46 
                 C 
               
               
                 ATOM 
                 1616 
                 C 
                 ALA 
                 A 
                 204 
                 96.443 
                 17.021 
                 −15.425 
                 1.00 
                 98.11 
                 C 
               
               
                 ATOM 
                 1617 
                 O 
                 ALA 
                 A 
                 204 
                 96.405 
                 16.857 
                 −14.206 
                 1.00 
                 102.18 
                 O 
               
               
                 ATOM 
                 1618 
                 N 
                 ASP 
                 A 
                 205 
                 95.361 
                 17.206 
                 −16.176 
                 1.00 
                 103.96 
                 N 
               
               
                 ATOM 
                 1619 
                 CA 
                 ASP 
                 A 
                 205 
                 94.000 
                 17.120 
                 −15.642 
                 1.00 
                 110.17 
                 C 
               
               
                 ATOM 
                 1620 
                 CB 
                 ASP 
                 A 
                 205 
                 93.586 
                 18.402 
                 −14.895 
                 1.00 
                 112.33 
                 C 
               
               
                 ATOM 
                 1621 
                 CG 
                 ASP 
                 A 
                 205 
                 93.754 
                 19.665 
                 −15.729 
                 1.00 
                 113.97 
                 C 
               
               
                 ATOM 
                 1622 
                 OD1 
                 ASP 
                 A 
                 205 
                 94.538 
                 19.648 
                 −16.705 
                 1.00 
                 121.66 
                 O 
               
               
                 ATOM 
                 1623 
                 OD2 
                 ASP 
                 A 
                 205 
                 93.104 
                 20.682 
                 −15.395 
                 1.00 
                 108.73 
                 O 
               
               
                 ATOM 
                 1624 
                 C 
                 ASP 
                 A 
                 205 
                 93.024 
                 16.790 
                 −16.777 
                 1.00 
                 110.88 
                 C 
               
               
                 ATOM 
                 1625 
                 O 
                 ASP 
                 A 
                 205 
                 92.516 
                 17.692 
                 −17.446 
                 1.00 
                 112.06 
                 O 
               
               
                 ATOM 
                 1626 
                 N 
                 PRO 
                 A 
                 206 
                 92.781 
                 15.487 
                 −17.013 
                 1.00 
                 110.76 
                 N 
               
               
                 ATOM 
                 1627 
                 CA 
                 PRO 
                 A 
                 206 
                 91.870 
                 15.035 
                 −18.068 
                 1.00 
                 113.60 
                 C 
               
               
                 ATOM 
                 1628 
                 CB 
                 PRO 
                 A 
                 206 
                 91.710 
                 13.543 
                 −17.767 
                 1.00 
                 113.91 
                 C 
               
               
                 ATOM 
                 1629 
                 CG 
                 PRO 
                 A 
                 206 
                 92.992 
                 13.157 
                 −17.117 
                 1.00 
                 113.31 
                 C 
               
               
                 ATOM 
                 1630 
                 CD 
                 PRO 
                 A 
                 206 
                 93.432 
                 14.354 
                 −16.327 
                 1.00 
                 111.03 
                 C 
               
               
                 ATOM 
                 1631 
                 C 
                 PRO 
                 A 
                 206 
                 90.500 
                 15.726 
                 −18.064 
                 1.00 
                 115.91 
                 C 
               
               
                 ATOM 
                 1632 
                 O 
                 PRO 
                 A 
                 206 
                 89.961 
                 16.030 
                 −19.131 
                 1.00 
                 114.76 
                 O 
               
               
                 ATOM 
                 1633 
                 N 
                 ASP 
                 A 
                 207 
                 89.960 
                 15.974 
                 −16.872 
                 1.00 
                 115.90 
                 N 
               
               
                 ATOM 
                 1634 
                 CA 
                 ASP 
                 A 
                 207 
                 88.638 
                 16.587 
                 −16.709 
                 1.00 
                 115.10 
                 C 
               
               
                 ATOM 
                 1635 
                 CB 
                 ASP 
                 A 
                 207 
                 88.322 
                 16.779 
                 −15.220 
                 1.00 
                 116.51 
                 C 
               
               
                 ATOM 
                 1636 
                 CG 
                 ASP 
                 A 
                 207 
                 88.249 
                 15.466 
                 −14.456 
                 1.00 
                 118.65 
                 C 
               
               
                 ATOM 
                 1637 
                 OD1 
                 ASP 
                 A 
                 207 
                 88.492 
                 14.399 
                 −15.061 
                 1.00 
                 120.29 
                 O 
               
               
                 ATOM 
                 1638 
                 OD2 
                 ASP 
                 A 
                 207 
                 87.950 
                 15.505 
                 −13.244 
                 1.00 
                 117.90 
                 O 
               
               
                 ATOM 
                 1639 
                 C 
                 ASP 
                 A 
                 207 
                 88.484 
                 17.927 
                 −17.428 
                 1.00 
                 114.57 
                 C 
               
               
                 ATOM 
                 1640 
                 O 
                 ASP 
                 A 
                 207 
                 87.439 
                 18.192 
                 −18.023 
                 1.00 
                 120.87 
                 O 
               
               
                 ATOM 
                 1641 
                 N 
                 HIS 
                 A 
                 208 
                 89.521 
                 18.760 
                 −17.376 
                 1.00 
                 113.32 
                 N 
               
               
                 ATOM 
                 1642 
                 CA 
                 HIS 
                 A 
                 208 
                 89.483 
                 20.096 
                 −17.988 
                 1.00 
                 113.45 
                 C 
               
               
                 ATOM 
                 1643 
                 CB 
                 HIS 
                 A 
                 208 
                 90.067 
                 21.132 
                 −17.017 
                 1.00 
                 115.37 
                 C 
               
               
                 ATOM 
                 1644 
                 CG 
                 HIS 
                 A 
                 208 
                 89.172 
                 21.444 
                 −15.857 
                 1.00 
                 117.34 
                 C 
               
               
                 ATOM 
                 1645 
                 ND1 
                 HIS 
                 A 
                 208 
                 88.893 
                 20.531 
                 −14.863 
                 1.00 
                 120.15 
                 N 
               
               
                 ATOM 
                 1646 
                 CE1 
                 HIS 
                 A 
                 208 
                 88.082 
                 21.080 
                 −13.975 
                 1.00 
                 119.71 
                 C 
               
               
                 ATOM 
                 1647 
                 NE2 
                 HIS 
                 A 
                 208 
                 87.829 
                 22.320 
                 −14.355 
                 1.00 
                 121.26 
                 N 
               
               
                 ATOM 
                 1648 
                 CD2 
                 HIS 
                 A 
                 208 
                 88.499 
                 22.573 
                 −15.528 
                 1.00 
                 119.91 
                 C 
               
               
                 ATOM 
                 1649 
                 C 
                 HIS 
                 A 
                 208 
                 90.182 
                 20.175 
                 −19.356 
                 1.00 
                 112.20 
                 C 
               
               
                 ATOM 
                 1650 
                 O 
                 HIS 
                 A 
                 208 
                 90.581 
                 21.259 
                 −19.788 
                 1.00 
                 107.64 
                 O 
               
               
                 ATOM 
                 1651 
                 N 
                 GLY 
                 A 
                 209 
                 90.323 
                 19.037 
                 −20.036 
                 1.00 
                 114.07 
                 N 
               
               
                 ATOM 
                 1652 
                 CA 
                 GLY 
                 A 
                 209 
                 90.876 
                 19.007 
                 −21.392 
                 1.00 
                 116.91 
                 C 
               
               
                 ATOM 
                 1653 
                 C 
                 GLY 
                 A 
                 209 
                 92.220 
                 18.320 
                 −21.533 
                 1.00 
                 121.22 
                 C 
               
               
                 ATOM 
                 1654 
                 O 
                 GLY 
                 A 
                 209 
                 92.299 
                 17.200 
                 −22.040 
                 1.00 
                 125.14 
                 O 
               
               
                 ATOM 
                 1655 
                 N 
                 LYS 
                 A 
                 210 
                 93.276 
                 18.995 
                 −21.081 
                 1.00 
                 123.83 
                 N 
               
               
                 ATOM 
                 1656 
                 CA 
                 LYS 
                 A 
                 210 
                 94.650 
                 18.501 
                 −21.232 
                 1.00 
                 123.76 
                 C 
               
               
                 ATOM 
                 1657 
                 CB 
                 LYS 
                 A 
                 210 
                 95.645 
                 19.588 
                 −20.823 
                 1.00 
                 129.30 
                 C 
               
               
                 ATOM 
                 1658 
                 CG 
                 LYS 
                 A 
                 210 
                 95.595 
                 20.797 
                 −21.742 
                 1.00 
                 137.32 
                 C 
               
               
                 ATOM 
                 1659 
                 CD 
                 LYS 
                 A 
                 210 
                 96.602 
                 21.857 
                 −21.349 
                 1.00 
                 141.35 
                 C 
               
               
                 ATOM 
                 1660 
                 CE 
                 LYS 
                 A 
                 210 
                 96.470 
                 23.076 
                 −22.249 
                 1.00 
                 142.74 
                 C 
               
               
                 ATOM 
                 1661 
                 NZ 
                 LYS 
                 A 
                 210 
                 97.345 
                 24.190 
                 −21.804 
                 1.00 
                 145.82 
                 N 
               
               
                 ATOM 
                 1662 
                 C 
                 LYS 
                 A 
                 210 
                 94.936 
                 17.227 
                 −20.440 
                 1.00 
                 118.22 
                 C 
               
               
                 ATOM 
                 1663 
                 O 
                 LYS 
                 A 
                 210 
                 94.935 
                 17.261 
                 −19.210 
                 1.00 
                 115.67 
                 O 
               
               
                 ATOM 
                 1664 
                 N 
                 PRO 
                 A 
                 211 
                 95.191 
                 16.103 
                 −21.144 
                 1.00 
                 112.92 
                 N 
               
               
                 ATOM 
                 1665 
                 CA 
                 PRO 
                 A 
                 211 
                 95.491 
                 14.842 
                 −20.476 
                 1.00 
                 111.37 
                 C 
               
               
                 ATOM 
                 1666 
                 CB 
                 PRO 
                 A 
                 211 
                 94.974 
                 13.806 
                 −21.474 
                 1.00 
                 111.45 
                 C 
               
               
                 ATOM 
                 1667 
                 CG 
                 PRO 
                 A 
                 211 
                 95.191 
                 14.441 
                 −22.807 
                 1.00 
                 112.22 
                 C 
               
               
                 ATOM 
                 1668 
                 CD 
                 PRO 
                 A 
                 211 
                 95.187 
                 15.936 
                 −22.612 
                 1.00 
                 112.40 
                 C 
               
               
                 ATOM 
                 1669 
                 C 
                 PRO 
                 A 
                 211 
                 96.986 
                 14.615 
                 −20.204 
                 1.00 
                 108.39 
                 C 
               
               
                 ATOM 
                 1670 
                 O 
                 PRO 
                 A 
                 211 
                 97.336 
                 13.704 
                 −19.453 
                 1.00 
                 106.62 
                 O 
               
               
                 ATOM 
                 1671 
                 N 
                 ASP 
                 A 
                 212 
                 97.850 
                 15.431 
                 −20.808 
                 1.00 
                 106.42 
                 N 
               
               
                 ATOM 
                 1672 
                 CA 
                 ASP 
                 A 
                 212 
                 99.298 
                 15.296 
                 −20.656 
                 1.00 
                 105.63 
                 C 
               
               
                 ATOM 
                 1673 
                 CB 
                 ASP 
                 A 
                 212 
                 99.967 
                 15.171 
                 −22.029 
                 1.00 
                 108.37 
                 C 
               
               
                 ATOM 
                 1674 
                 CG 
                 ASP 
                 A 
                 212 
                 99.534 
                 13.927 
                 −22.786 
                 1.00 
                 111.39 
                 C 
               
               
                 ATOM 
                 1675 
                 OD1 
                 ASP 
                 A 
                 212 
                 99.239 
                 12.896 
                 −22.141 
                 1.00 
                 110.82 
                 O 
               
               
                 ATOM 
                 1676 
                 OD2 
                 ASP 
                 A 
                 212 
                 99.505 
                 13.982 
                 −24.034 
                 1.00 
                 113.97 
                 O 
               
               
                 ATOM 
                 1677 
                 C 
                 ASP 
                 A 
                 212 
                 99.883 
                 16.499 
                 −19.930 
                 1.00 
                 101.27 
                 C 
               
               
                 ATOM 
                 1678 
                 O 
                 ASP 
                 A 
                 212 
                 99.555 
                 17.644 
                 −20.248 
                 1.00 
                 99.99 
                 O 
               
               
                 ATOM 
                 1679 
                 N 
                 ALA 
                 A 
                 213 
                 100.766 
                 16.234 
                 −18.970 
                 1.00 
                 96.39 
                 N 
               
               
                 ATOM 
                 1680 
                 CA 
                 ALA 
                 A 
                 213 
                 101.421 
                 17.292 
                 −18.205 
                 1.00 
                 92.95 
                 C 
               
               
                 ATOM 
                 1681 
                 CB 
                 ALA 
                 A 
                 213 
                 102.143 
                 16.702 
                 −17.007 
                 1.00 
                 93.67 
                 C 
               
               
                 ATOM 
                 1682 
                 C 
                 ALA 
                 A 
                 213 
                 102.404 
                 18.066 
                 −19.077 
                 1.00 
                 90.86 
                 C 
               
               
                 ATOM 
                 1683 
                 O 
                 ALA 
                 A 
                 213 
                 102.891 
                 17.548 
                 −20.081 
                 1.00 
                 91.44 
                 O 
               
               
                 ATOM 
                 1684 
                 N 
                 VAL 
                 A 
                 214 
                 102.694 
                 19.303 
                 −18.683 
                 1.00 
                 89.07 
                 N 
               
               
                 ATOM 
                 1685 
                 CA 
                 VAL 
                 A 
                 214 
                 103.615 
                 20.160 
                 −19.426 
                 1.00 
                 90.36 
                 C 
               
               
                 ATOM 
                 1686 
                 CB 
                 VAL 
                 A 
                 214 
                 102.894 
                 21.402 
                 −19.986 
                 1.00 
                 90.82 
                 C 
               
               
                 ATOM 
                 1687 
                 CG1 
                 VAL 
                 A 
                 214 
                 103.848 
                 22.256 
                 −20.817 
                 1.00 
                 92.38 
                 C 
               
               
                 ATOM 
                 1688 
                 CG2 
                 VAL 
                 A 
                 214 
                 101.700 
                 20.974 
                 −20.828 
                 1.00 
                 92.12 
                 C 
               
               
                 ATOM 
                 1689 
                 C 
                 VAL 
                 A 
                 214 
                 104.780 
                 20.571 
                 −18.519 
                 1.00 
                 92.80 
                 C 
               
               
                 ATOM 
                 1690 
                 O 
                 VAL 
                 A 
                 214 
                 104.756 
                 21.652 
                 −17.931 
                 1.00 
                 94.19 
                 O 
               
               
                 ATOM 
                 1691 
                 N 
                 PRO 
                 A 
                 215 
                 105.809 
                 19.705 
                 −18.408 
                 1.00 
                 93.71 
                 N 
               
               
                 ATOM 
                 1692 
                 CA 
                 PRO 
                 A 
                 215 
                 106.980 
                 19.938 
                 −17.548 
                 1.00 
                 93.49 
                 C 
               
               
                 ATOM 
                 1693 
                 CB 
                 PRO 
                 A 
                 215 
                 108.004 
                 18.906 
                 −18.037 
                 1.00 
                 93.83 
                 C 
               
               
                 ATOM 
                 1694 
                 CG 
                 PRO 
                 A 
                 215 
                 107.254 
                 17.909 
                 −18.850 
                 1.00 
                 94.23 
                 C 
               
               
                 ATOM 
                 1695 
                 CD 
                 PRO 
                 A 
                 215 
                 105.857 
                 18.391 
                 −19.077 
                 1.00 
                 93.70 
                 C 
               
               
                 ATOM 
                 1696 
                 C 
                 PRO 
                 A 
                 215 
                 107.585 
                 21.339 
                 −17.653 
                 1.00 
                 94.44 
                 C 
               
               
                 ATOM 
                 1697 
                 O 
                 PRO 
                 A 
                 215 
                 108.031 
                 21.893 
                 −16.649 
                 1.00 
                 95.00 
                 O 
               
               
                 ATOM 
                 1698 
                 N 
                 GLY 
                 A 
                 216 
                 107.604 
                 21.896 
                 −18.861 
                 1.00 
                 93.59 
                 N 
               
               
                 ATOM 
                 1699 
                 CA 
                 GLY 
                 A 
                 216 
                 108.176 
                 23.218 
                 −19.100 
                 1.00 
                 91.57 
                 C 
               
               
                 ATOM 
                 1700 
                 C 
                 GLY 
                 A 
                 216 
                 107.431 
                 24.382 
                 −18.468 
                 1.00 
                 91.34 
                 C 
               
               
                 ATOM 
                 1701 
                 O 
                 GLY 
                 A 
                 216 
                 107.971 
                 25.484 
                 −18.381 
                 1.00 
                 93.81 
                 O 
               
               
                 ATOM 
                 1702 
                 N 
                 ASN 
                 A 
                 217 
                 106.196 
                 24.145 
                 −18.030 
                 1.00 
                 90.53 
                 N 
               
               
                 ATOM 
                 1703 
                 CA 
                 ASN 
                 A 
                 217 
                 105.355 
                 25.193 
                 −17.451 
                 1.00 
                 89.29 
                 C 
               
               
                 ATOM 
                 1704 
                 CB 
                 ASN 
                 A 
                 217 
                 103.918 
                 24.992 
                 −17.933 
                 1.00 
                 87.44 
                 C 
               
               
                 ATOM 
                 1705 
                 CG 
                 ASN 
                 A 
                 217 
                 103.098 
                 26.271 
                 −17.916 
                 1.00 
                 86.60 
                 C 
               
               
                 ATOM 
                 1706 
                 OD1 
                 ASN 
                 A 
                 217 
                 103.606 
                 27.361 
                 −18.182 
                 1.00 
                 82.24 
                 O 
               
               
                 ATOM 
                 1707 
                 ND2 
                 ASN 
                 A 
                 217 
                 101.812 
                 26.133 
                 −17.613 
                 1.00 
                 88.48 
                 N 
               
               
                 ATOM 
                 1708 
                 C 
                 ASN 
                 A 
                 217 
                 105.377 
                 25.209 
                 −15.921 
                 1.00 
                 90.89 
                 C 
               
               
                 ATOM 
                 1709 
                 O 
                 ASN 
                 A 
                 217 
                 104.729 
                 26.049 
                 −15.301 
                 1.00 
                 93.27 
                 O 
               
               
                 ATOM 
                 1710 
                 N 
                 CYS 
                 A 
                 218 
                 106.122 
                 24.285 
                 −15.321 
                 1.00 
                 92.57 
                 N 
               
               
                 ATOM 
                 1711 
                 CA 
                 CYS 
                 A 
                 218 
                 106.186 
                 24.151 
                 −13.861 
                 1.00 
                 92.13 
                 C 
               
               
                 ATOM 
                 1712 
                 CB 
                 CYS 
                 A 
                 218 
                 106.800 
                 22.797 
                 −13.471 
                 1.00 
                 95.46 
                 C 
               
               
                 ATOM 
                 1713 
                 SG 
                 CYS 
                 A 
                 218 
                 105.647 
                 21.446 
                 −13.139 
                 1.00 
                 101.99 
                 S 
               
               
                 ATOM 
                 1714 
                 C 
                 CYS 
                 A 
                 218 
                 106.993 
                 25.242 
                 −13.171 
                 1.00 
                 89.73 
                 C 
               
               
                 ATOM 
                 1715 
                 O 
                 CYS 
                 A 
                 218 
                 107.875 
                 25.855 
                 −13.769 
                 1.00 
                 90.36 
                 O 
               
               
                 ATOM 
                 1716 
                 N 
                 THR 
                 A 
                 219 
                 106.663 
                 25.468 
                 −11.902 
                 1.00 
                 89.47 
                 N 
               
               
                 ATOM 
                 1717 
                 CA 
                 THR 
                 A 
                 219 
                 107.444 
                 26.320 
                 −11.015 
                 1.00 
                 89.67 
                 C 
               
               
                 ATOM 
                 1718 
                 CB 
                 THR 
                 A 
                 219 
                 106.547 
                 27.210 
                 −10.139 
                 1.00 
                 89.31 
                 C 
               
               
                 ATOM 
                 1719 
                 OG1 
                 THR 
                 A 
                 219 
                 105.719 
                 28.023 
                 −10.977 
                 1.00 
                 89.54 
                 O 
               
               
                 ATOM 
                 1720 
                 CG2 
                 THR 
                 A 
                 219 
                 107.386 
                 28.109 
                 −9.241 
                 1.00 
                 89.94 
                 C 
               
               
                 ATOM 
                 1721 
                 C 
                 THR 
                 A 
                 219 
                 108.222 
                 25.325 
                 −10.157 
                 1.00 
                 89.67 
                 C 
               
               
                 ATOM 
                 1722 
                 O 
                 THR 
                 A 
                 219 
                 107.624 
                 24.568 
                 −9.388 
                 1.00 
                 88.45 
                 O 
               
               
                 ATOM 
                 1723 
                 N 
                 TYR 
                 A 
                 220 
                 109.546 
                 25.319 
                 −10.295 
                 1.00 
                 88.06 
                 N 
               
               
                 ATOM 
                 1724 
                 CA 
                 TYR 
                 A 
                 220 
                 110.376 
                 24.283 
                 −9.673 
                 1.00 
                 87.99 
                 C 
               
               
                 ATOM 
                 1725 
                 CB 
                 TYR 
                 A 
                 220 
                 111.469 
                 23.834 
                 −10.651 
                 1.00 
                 85.51 
                 C 
               
               
                 ATOM 
                 1726 
                 CG 
                 TYR 
                 A 
                 220 
                 110.940 
                 22.896 
                 −11.707 
                 1.00 
                 84.82 
                 C 
               
               
                 ATOM 
                 1727 
                 CD1 
                 TYR 
                 A 
                 220 
                 110.797 
                 21.540 
                 −11.438 
                 1.00 
                 85.64 
                 C 
               
               
                 ATOM 
                 1728 
                 CE1 
                 TYR 
                 A 
                 220 
                 110.303 
                 20.669 
                 −12.390 
                 1.00 
                 87.79 
                 C 
               
               
                 ATOM 
                 1729 
                 CZ 
                 TYR 
                 A 
                 220 
                 109.938 
                 21.150 
                 −13.629 
                 1.00 
                 87.64 
                 C 
               
               
                 ATOM 
                 1730 
                 OH 
                 TYR 
                 A 
                 220 
                 109.447 
                 20.273 
                 −14.565 
                 1.00 
                 92.31 
                 O 
               
               
                 ATOM 
                 1731 
                 CE2 
                 TYR 
                 A 
                 220 
                 110.066 
                 22.495 
                 −13.923 
                 1.00 
                 85.64 
                 C 
               
               
                 ATOM 
                 1732 
                 CD2 
                 TYR 
                 A 
                 220 
                 110.560 
                 23.361 
                 −12.963 
                 1.00 
                 84.72 
                 C 
               
               
                 ATOM 
                 1733 
                 C 
                 TYR 
                 A 
                 220 
                 110.982 
                 24.613 
                 −8.309 
                 1.00 
                 89.61 
                 C 
               
               
                 ATOM 
                 1734 
                 O 
                 TYR 
                 A 
                 220 
                 111.157 
                 23.715 
                 −7.484 
                 1.00 
                 90.52 
                 O 
               
               
                 ATOM 
                 1735 
                 N 
                 GLY 
                 A 
                 221 
                 111.296 
                 25.879 
                 −8.060 
                 1.00 
                 88.76 
                 N 
               
               
                 ATOM 
                 1736 
                 CA 
                 GLY 
                 A 
                 221 
                 111.916 
                 26.265 
                 −6.791 
                 1.00 
                 88.20 
                 C 
               
               
                 ATOM 
                 1737 
                 C 
                 GLY 
                 A 
                 221 
                 110.953 
                 26.231 
                 −5.612 
                 1.00 
                 84.48 
                 C 
               
               
                 ATOM 
                 1738 
                 O 
                 GLY 
                 A 
                 221 
                 110.070 
                 25.375 
                 −5.532 
                 1.00 
                 80.92 
                 O 
               
               
                 ATOM 
                 1739 
                 N 
                 ALA 
                 A 
                 222 
                 111.142 
                 27.164 
                 −4.684 
                 1.00 
                 81.28 
                 N 
               
               
                 ATOM 
                 1740 
                 CA 
                 ALA 
                 A 
                 222 
                 110.228 
                 27.326 
                 −3.564 
                 1.00 
                 79.28 
                 C 
               
               
                 ATOM 
                 1741 
                 CB 
                 ALA 
                 A 
                 222 
                 110.833 
                 28.242 
                 −2.510 
                 1.00 
                 80.09 
                 C 
               
               
                 ATOM 
                 1742 
                 C 
                 ALA 
                 A 
                 222 
                 108.935 
                 27.919 
                 −4.105 
                 1.00 
                 76.65 
                 C 
               
               
                 ATOM 
                 1743 
                 O 
                 ALA 
                 A 
                 222 
                 108.970 
                 28.817 
                 −4.947 
                 1.00 
                 77.00 
                 O 
               
               
                 ATOM 
                 1744 
                 N 
                 LYS 
                 A 
                 223 
                 107.799 
                 27.420 
                 −3.628 
                 1.00 
                 75.17 
                 N 
               
               
                 ATOM 
                 1745 
                 CA 
                 LYS 
                 A 
                 223 
                 106.499 
                 27.890 
                 −4.102 
                 1.00 
                 73.94 
                 C 
               
               
                 ATOM 
                 1746 
                 CB 
                 LYS 
                 A 
                 223 
                 105.717 
                 26.727 
                 −4.719 
                 1.00 
                 74.06 
                 C 
               
               
                 ATOM 
                 1747 
                 CG 
                 LYS 
                 A 
                 223 
                 106.187 
                 26.356 
                 −6.117 
                 1.00 
                 72.01 
                 C 
               
               
                 ATOM 
                 1748 
                 CD 
                 LYS 
                 A 
                 223 
                 105.382 
                 25.206 
                 −6.701 
                 1.00 
                 70.96 
                 C 
               
               
                 ATOM 
                 1749 
                 CE 
                 LYS 
                 A 
                 223 
                 105.802 
                 23.859 
                 −6.137 
                 1.00 
                 70.20 
                 C 
               
               
                 ATOM 
                 1750 
                 NZ 
                 LYS 
                 A 
                 223 
                 107.178 
                 23.471 
                 −6.561 
                 1.00 
                 69.98 
                 N 
               
               
                 ATOM 
                 1751 
                 C 
                 LYS 
                 A 
                 223 
                 105.666 
                 28.563 
                 −3.014 
                 1.00 
                 72.76 
                 C 
               
               
                 ATOM 
                 1752 
                 O 
                 LYS 
                 A 
                 223 
                 105.661 
                 28.132 
                 −1.863 
                 1.00 
                 77.03 
                 O 
               
               
                 ATOM 
                 1753 
                 N 
                 GLN 
                 A 
                 224 
                 104.959 
                 29.622 
                 −3.399 
                 1.00 
                 71.94 
                 N 
               
               
                 ATOM 
                 1754 
                 CA 
                 GLN 
                 A 
                 224 
                 104.062 
                 30.330 
                 −2.490 
                 1.00 
                 71.49 
                 C 
               
               
                 ATOM 
                 1755 
                 CB 
                 GLN 
                 A 
                 224 
                 103.700 
                 31.707 
                 −3.047 
                 1.00 
                 69.85 
                 C 
               
               
                 ATOM 
                 1756 
                 CG 
                 GLN 
                 A 
                 224 
                 104.875 
                 32.633 
                 −3.299 
                 1.00 
                 67.77 
                 C 
               
               
                 ATOM 
                 1757 
                 CD 
                 GLN 
                 A 
                 224 
                 104.429 
                 34.012 
                 −3.742 
                 1.00 
                 67.40 
                 C 
               
               
                 ATOM 
                 1758 
                 OE1 
                 GLN 
                 A 
                 224 
                 103.238 
                 34.263 
                 −3.939 
                 1.00 
                 68.00 
                 O 
               
               
                 ATOM 
                 1759 
                 NE2 
                 GLN 
                 A 
                 224 
                 105.384 
                 34.919 
                 −3.894 
                 1.00 
                 68.81 
                 N 
               
               
                 ATOM 
                 1760 
                 C 
                 GLN 
                 A 
                 224 
                 102.772 
                 29.537 
                 −2.320 
                 1.00 
                 71.05 
                 C 
               
               
                 ATOM 
                 1761 
                 O 
                 GLN 
                 A 
                 224 
                 102.475 
                 28.664 
                 −3.132 
                 1.00 
                 72.16 
                 O 
               
               
                 ATOM 
                 1762 
                 N 
                 PRO 
                 A 
                 225 
                 101.989 
                 29.846 
                 −1.270 
                 1.00 
                 72.77 
                 N 
               
               
                 ATOM 
                 1763 
                 CA 
                 PRO 
                 A 
                 225 
                 100.696 
                 29.177 
                 −1.136 
                 1.00 
                 72.88 
                 C 
               
               
                 ATOM 
                 1764 
                 CB 
                 PRO 
                 A 
                 225 
                 100.196 
                 29.624 
                 0.248 
                 1.00 
                 72.02 
                 C 
               
               
                 ATOM 
                 1765 
                 CG 
                 PRO 
                 A 
                 225 
                 101.396 
                 30.150 
                 0.956 
                 1.00 
                 73.36 
                 C 
               
               
                 ATOM 
                 1766 
                 CD 
                 PRO 
                 A 
                 225 
                 102.278 
                 30.714 
                 −0.116 
                 1.00 
                 73.96 
                 C 
               
               
                 ATOM 
                 1767 
                 C 
                 PRO 
                 A 
                 225 
                 99.735 
                 29.633 
                 −2.230 
                 1.00 
                 72.69 
                 C 
               
               
                 ATOM 
                 1768 
                 O 
                 PRO 
                 A 
                 225 
                 99.995 
                 30.629 
                 −2.903 
                 1.00 
                 73.43 
                 O 
               
               
                 ATOM 
                 1769 
                 N 
                 LEU 
                 A 
                 226 
                 98.637 
                 28.904 
                 −2.397 
                 1.00 
                 72.76 
                 N 
               
               
                 ATOM 
                 1770 
                 CA 
                 LEU 
                 A 
                 226 
                 97.638 
                 29.223 
                 −3.411 
                 1.00 
                 71.49 
                 C 
               
               
                 ATOM 
                 1771 
                 CB 
                 LEU 
                 A 
                 226 
                 96.976 
                 27.935 
                 −3.908 
                 1.00 
                 71.67 
                 C 
               
               
                 ATOM 
                 1772 
                 CG 
                 LEU 
                 A 
                 226 
                 97.921 
                 26.901 
                 −4.523 
                 1.00 
                 72.47 
                 C 
               
               
                 ATOM 
                 1773 
                 CD1 
                 LEU 
                 A 
                 226 
                 97.232 
                 25.551 
                 −4.637 
                 1.00 
                 72.82 
                 C 
               
               
                 ATOM 
                 1774 
                 CD2 
                 LEU 
                 A 
                 226 
                 98.436 
                 27.365 
                 −5.879 
                 1.00 
                 73.04 
                 C 
               
               
                 ATOM 
                 1775 
                 C 
                 LEU 
                 A 
                 226 
                 96.579 
                 30.175 
                 −2.857 
                 1.00 
                 71.78 
                 C 
               
               
                 ATOM 
                 1776 
                 O 
                 LEU 
                 A 
                 226 
                 95.613 
                 29.740 
                 −2.222 
                 1.00 
                 75.71 
                 O 
               
               
                 ATOM 
                 1777 
                 N 
                 TYR 
                 A 
                 227 
                 96.773 
                 31.474 
                 −3.083 
                 1.00 
                 69.55 
                 N 
               
               
                 ATOM 
                 1778 
                 CA 
                 TYR 
                 A 
                 227 
                 95.798 
                 32.485 
                 −2.666 
                 1.00 
                 70.32 
                 C 
               
               
                 ATOM 
                 1779 
                 CB 
                 TYR 
                 A 
                 227 
                 96.469 
                 33.819 
                 −2.358 
                 1.00 
                 70.40 
                 C 
               
               
                 ATOM 
                 1780 
                 CG 
                 TYR 
                 A 
                 227 
                 97.631 
                 33.712 
                 −1.404 
                 1.00 
                 70.85 
                 C 
               
               
                 ATOM 
                 1781 
                 CD1 
                 TYR 
                 A 
                 227 
                 97.499 
                 33.054 
                 −0.183 
                 1.00 
                 72.80 
                 C 
               
               
                 ATOM 
                 1782 
                 CE1 
                 TYR 
                 A 
                 227 
                 98.562 
                 32.964 
                 0.702 
                 1.00 
                 71.55 
                 C 
               
               
                 ATOM 
                 1783 
                 CZ 
                 TYR 
                 A 
                 227 
                 99.771 
                 33.541 
                 0.371 
                 1.00 
                 71.70 
                 C 
               
               
                 ATOM 
                 1784 
                 OH 
                 TYR 
                 A 
                 227 
                 100.833 
                 33.460 
                 1.236 
                 1.00 
                 71.35 
                 O 
               
               
                 ATOM 
                 1785 
                 CE2 
                 TYR 
                 A 
                 227 
                 99.925 
                 34.200 
                 −0.833 
                 1.00 
                 73.08 
                 C 
               
               
                 ATOM 
                 1786 
                 CD2 
                 TYR 
                 A 
                 227 
                 98.858 
                 34.285 
                 −1.710 
                 1.00 
                 71.37 
                 C 
               
               
                 ATOM 
                 1787 
                 C 
                 TYR 
                 A 
                 227 
                 94.801 
                 32.649 
                 −3.800 
                 1.00 
                 69.55 
                 C 
               
               
                 ATOM 
                 1788 
                 O 
                 TYR 
                 A 
                 227 
                 95.157 
                 33.101 
                 −4.890 
                 1.00 
                 66.57 
                 O 
               
               
                 ATOM 
                 1789 
                 N 
                 TRP 
                 A 
                 228 
                 93.548 
                 32.300 
                 −3.531 
                 1.00 
                 70.33 
                 N 
               
               
                 ATOM 
                 1790 
                 CA 
                 TRP 
                 A 
                 228 
                 92.557 
                 32.191 
                 −4.585 
                 1.00 
                 70.72 
                 C 
               
               
                 ATOM 
                 1791 
                 CB 
                 TRP 
                 A 
                 228 
                 92.648 
                 30.765 
                 −5.144 
                 1.00 
                 70.69 
                 C 
               
               
                 ATOM 
                 1792 
                 CG 
                 TRP 
                 A 
                 228 
                 91.719 
                 30.467 
                 −6.247 
                 1.00 
                 70.07 
                 C 
               
               
                 ATOM 
                 1793 
                 CD1 
                 TRP 
                 A 
                 228 
                 91.780 
                 30.943 
                 −7.518 
                 1.00 
                 71.56 
                 C 
               
               
                 ATOM 
                 1794 
                 NE1 
                 TRP 
                 A 
                 228 
                 90.750 
                 30.431 
                 −8.263 
                 1.00 
                 71.58 
                 N 
               
               
                 ATOM 
                 1795 
                 CE2 
                 TRP 
                 A 
                 228 
                 90.004 
                 29.601 
                 −7.472 
                 1.00 
                 68.67 
                 C 
               
               
                 ATOM 
                 1796 
                 CD2 
                 TRP 
                 A 
                 228 
                 90.592 
                 29.598 
                 −6.194 
                 1.00 
                 68.31 
                 C 
               
               
                 ATOM 
                 1797 
                 CE3 
                 TRP 
                 A 
                 228 
                 90.020 
                 28.817 
                 −5.188 
                 1.00 
                 68.07 
                 C 
               
               
                 ATOM 
                 1798 
                 CZ3 
                 TRP 
                 A 
                 228 
                 88.899 
                 28.087 
                 −5.481 
                 1.00 
                 68.67 
                 C 
               
               
                 ATOM 
                 1799 
                 CH2 
                 TRP 
                 A 
                 228 
                 88.329 
                 28.114 
                 −6.767 
                 1.00 
                 69.73 
                 C 
               
               
                 ATOM 
                 1800 
                 CZ2 
                 TRP 
                 A 
                 228 
                 88.871 
                 28.862 
                 −7.770 
                 1.00 
                 69.10 
                 C 
               
               
                 ATOM 
                 1801 
                 C 
                 TRP 
                 A 
                 228 
                 91.139 
                 32.504 
                 −4.106 
                 1.00 
                 71.61 
                 C 
               
               
                 ATOM 
                 1802 
                 O 
                 TRP 
                 A 
                 228 
                 90.819 
                 32.346 
                 −2.928 
                 1.00 
                 70.99 
                 O 
               
               
                 ATOM 
                 1803 
                 N 
                 LEU 
                 A 
                 229 
                 90.312 
                 32.980 
                 −5.035 
                 1.00 
                 74.68 
                 N 
               
               
                 ATOM 
                 1804 
                 CA 
                 LEU 
                 A 
                 229 
                 88.887 
                 33.246 
                 −4.803 
                 1.00 
                 75.33 
                 C 
               
               
                 ATOM 
                 1805 
                 CB 
                 LEU 
                 A 
                 229 
                 88.181 
                 31.963 
                 −4.351 
                 1.00 
                 74.13 
                 C 
               
               
                 ATOM 
                 1806 
                 CG 
                 LEU 
                 A 
                 229 
                 86.713 
                 31.815 
                 −4.751 
                 1.00 
                 75.62 
                 C 
               
               
                 ATOM 
                 1807 
                 CD1 
                 LEU 
                 A 
                 229 
                 86.613 
                 31.384 
                 −6.209 
                 1.00 
                 75.47 
                 C 
               
               
                 ATOM 
                 1808 
                 CD2 
                 LEU 
                 A 
                 229 
                 86.015 
                 30.802 
                 −3.857 
                 1.00 
                 76.28 
                 C 
               
               
                 ATOM 
                 1809 
                 C 
                 LEU 
                 A 
                 229 
                 88.607 
                 34.376 
                 −3.803 
                 1.00 
                 76.75 
                 C 
               
               
                 ATOM 
                 1810 
                 O 
                 LEU 
                 A 
                 229 
                 87.518 
                 34.435 
                 −3.232 
                 1.00 
                 78.50 
                 O 
               
               
                 ATOM 
                 1811 
                 N 
                 GLN 
                 A 
                 230 
                 89.568 
                 35.277 
                 −3.607 
                 1.00 
                 78.20 
                 N 
               
               
                 ATOM 
                 1812 
                 CA 
                 GLN 
                 A 
                 230 
                 89.400 
                 36.389 
                 −2.668 
                 1.00 
                 81.19 
                 C 
               
               
                 ATOM 
                 1813 
                 CB 
                 GLN 
                 A 
                 230 
                 90.621 
                 36.510 
                 −1.748 
                 1.00 
                 80.60 
                 C 
               
               
                 ATOM 
                 1814 
                 CG 
                 GLN 
                 A 
                 230 
                 90.956 
                 35.236 
                 −0.995 
                 1.00 
                 80.41 
                 C 
               
               
                 ATOM 
                 1815 
                 CD 
                 GLN 
                 A 
                 230 
                 89.756 
                 34.657 
                 −0.267 
                 1.00 
                 80.81 
                 C 
               
               
                 ATOM 
                 1816 
                 OE1 
                 GLN 
                 A 
                 230 
                 89.005 
                 35.378 
                 0.385 
                 1.00 
                 81.10 
                 O 
               
               
                 ATOM 
                 1817 
                 NE2 
                 GLN 
                 A 
                 230 
                 89.567 
                 33.350 
                 −0.383 
                 1.00 
                 80.45 
                 N 
               
               
                 ATOM 
                 1818 
                 C 
                 GLN 
                 A 
                 230 
                 89.173 
                 37.707 
                 −3.393 
                 1.00 
                 83.69 
                 C 
               
               
                 ATOM 
                 1819 
                 O 
                 GLN 
                 A 
                 230 
                 89.290 
                 37.785 
                 −4.615 
                 1.00 
                 85.42 
                 O 
               
               
                 ATOM 
                 1820 
                 N 
                 LYS 
                 A 
                 231 
                 88.852 
                 38.741 
                 −2.625 
                 1.00 
                 86.49 
                 N 
               
               
                 ATOM 
                 1821 
                 CA 
                 LYS 
                 A 
                 231 
                 88.640 
                 40.070 
                 −3.173 
                 1.00 
                 87.59 
                 C 
               
               
                 ATOM 
                 1822 
                 CB 
                 LYS 
                 A 
                 231 
                 87.760 
                 40.892 
                 −2.231 
                 1.00 
                 91.33 
                 C 
               
               
                 ATOM 
                 1823 
                 CG 
                 LYS 
                 A 
                 231 
                 87.261 
                 42.196 
                 −2.825 
                 1.00 
                 95.93 
                 C 
               
               
                 ATOM 
                 1824 
                 CD 
                 LYS 
                 A 
                 231 
                 86.089 
                 42.745 
                 −2.028 
                 1.00 
                 98.90 
                 C 
               
               
                 ATOM 
                 1825 
                 CE 
                 LYS 
                 A 
                 231 
                 85.572 
                 44.044 
                 −2.621 
                 1.00 
                 102.14 
                 C 
               
               
                 ATOM 
                 1826 
                 NZ 
                 LYS 
                 A 
                 231 
                 84.321 
                 44.487 
                 −1.950 
                 1.00 
                 104.65 
                 N 
               
               
                 ATOM 
                 1827 
                 C 
                 LYS 
                 A 
                 231 
                 89.971 
                 40.778 
                 −3.412 
                 1.00 
                 87.28 
                 C 
               
               
                 ATOM 
                 1828 
                 O 
                 LYS 
                 A 
                 231 
                 90.073 
                 41.614 
                 −4.307 
                 1.00 
                 88.94 
                 O 
               
               
                 ATOM 
                 1829 
                 N 
                 GLU 
                 A 
                 232 
                 90.986 
                 40.440 
                 −2.615 
                 1.00 
                 89.06 
                 N 
               
               
                 ATOM 
                 1830 
                 CA 
                 GLU 
                 A 
                 232 
                 92.305 
                 41.067 
                 −2.724 
                 1.00 
                 90.80 
                 C 
               
               
                 ATOM 
                 1831 
                 CB 
                 GLU 
                 A 
                 232 
                 92.448 
                 42.184 
                 −1.683 
                 1.00 
                 94.95 
                 C 
               
               
                 ATOM 
                 1832 
                 CG 
                 GLU 
                 A 
                 232 
                 91.340 
                 43.231 
                 −1.678 
                 1.00 
                 98.24 
                 C 
               
               
                 ATOM 
                 1833 
                 CD 
                 GLU 
                 A 
                 232 
                 91.492 
                 44.250 
                 −0.559 
                 1.00 
                 99.79 
                 C 
               
               
                 ATOM 
                 1834 
                 OE1 
                 GLU 
                 A 
                 232 
                 92.363 
                 44.064 
                 0.319 
                 1.00 
                 100.02 
                 O 
               
               
                 ATOM 
                 1835 
                 OE2 
                 GLU 
                 A 
                 232 
                 90.727 
                 45.237 
                 −0.549 
                 1.00 
                 101.71 
                 O 
               
               
                 ATOM 
                 1836 
                 C 
                 GLU 
                 A 
                 232 
                 93.449 
                 40.074 
                 −2.508 
                 1.00 
                 88.75 
                 C 
               
               
                 ATOM 
                 1837 
                 O 
                 GLU 
                 A 
                 232 
                 93.289 
                 39.063 
                 −1.825 
                 1.00 
                 87.80 
                 O 
               
               
                 ATOM 
                 1838 
                 N 
                 GLY 
                 A 
                 233 
                 94.604 
                 40.383 
                 −3.095 
                 1.00 
                 87.81 
                 N 
               
               
                 ATOM 
                 1839 
                 CA 
                 GLY 
                 A 
                 233 
                 95.838 
                 39.625 
                 −2.874 
                 1.00 
                 86.80 
                 C 
               
               
                 ATOM 
                 1840 
                 C 
                 GLY 
                 A 
                 233 
                 95.893 
                 38.203 
                 −3.401 
                 1.00 
                 85.56 
                 C 
               
               
                 ATOM 
                 1841 
                 O 
                 GLY 
                 A 
                 233 
                 96.456 
                 37.325 
                 −2.750 
                 1.00 
                 86.63 
                 O 
               
               
                 ATOM 
                 1842 
                 N 
                 ASN 
                 A 
                 234 
                 95.327 
                 37.978 
                 −4.582 
                 1.00 
                 85.54 
                 N 
               
               
                 ATOM 
                 1843 
                 CA 
                 ASN 
                 A 
                 234 
                 95.341 
                 36.658 
                 −5.210 
                 1.00 
                 85.24 
                 C 
               
               
                 ATOM 
                 1844 
                 CB 
                 ASN 
                 A 
                 234 
                 94.073 
                 36.455 
                 −6.043 
                 1.00 
                 85.03 
                 C 
               
               
                 ATOM 
                 1845 
                 CG 
                 ASN 
                 A 
                 234 
                 92.838 
                 36.264 
                 −5.192 
                 1.00 
                 84.34 
                 C 
               
               
                 ATOM 
                 1846 
                 OD1 
                 ASN 
                 A 
                 234 
                 92.732 
                 35.297 
                 −4.442 
                 1.00 
                 86.46 
                 O 
               
               
                 ATOM 
                 1847 
                 ND2 
                 ASN 
                 A 
                 234 
                 91.886 
                 37.171 
                 −5.322 
                 1.00 
                 85.12 
                 N 
               
               
                 ATOM 
                 1848 
                 C 
                 ASN 
                 A 
                 234 
                 96.554 
                 36.467 
                 −6.115 
                 1.00 
                 86.89 
                 C 
               
               
                 ATOM 
                 1849 
                 O 
                 ASN 
                 A 
                 234 
                 96.942 
                 37.384 
                 −6.843 
                 1.00 
                 87.53 
                 O 
               
               
                 ATOM 
                 1850 
                 N 
                 ASN 
                 A 
                 235 
                 97.151 
                 35.278 
                 −6.060 
                 1.00 
                 86.38 
                 N 
               
               
                 ATOM 
                 1851 
                 CA 
                 ASN 
                 A 
                 235 
                 98.233 
                 34.899 
                 −6.979 
                 1.00 
                 86.26 
                 C 
               
               
                 ATOM 
                 1852 
                 CB 
                 ASN 
                 A 
                 235 
                 99.465 
                 34.387 
                 −6.221 
                 1.00 
                 86.78 
                 C 
               
               
                 ATOM 
                 1853 
                 CG 
                 ASN 
                 A 
                 235 
                 99.156 
                 33.219 
                 −5.310 
                 1.00 
                 89.65 
                 C 
               
               
                 ATOM 
                 1854 
                 OD1 
                 ASN 
                 A 
                 235 
                 98.019 
                 32.754 
                 −5.232 
                 1.00 
                 91.82 
                 O 
               
               
                 ATOM 
                 1855 
                 ND2 
                 ASN 
                 A 
                 235 
                 100.173 
                 32.742 
                 −4.603 
                 1.00 
                 93.67 
                 N 
               
               
                 ATOM 
                 1856 
                 C 
                 ASN 
                 A 
                 235 
                 97.753 
                 33.875 
                 −8.019 
                 1.00 
                 86.12 
                 C 
               
               
                 ATOM 
                 1857 
                 O 
                 ASN 
                 A 
                 235 
                 98.416 
                 33.661 
                 −9.035 
                 1.00 
                 86.94 
                 O 
               
               
                 ATOM 
                 1858 
                 N 
                 GLU 
                 A 
                 236 
                 96.610 
                 33.240 
                 −7.749 
                 1.00 
                 84.08 
                 N 
               
               
                 ATOM 
                 1859 
                 CA 
                 GLU 
                 A 
                 236 
                 95.962 
                 32.338 
                 −8.697 
                 1.00 
                 84.15 
                 C 
               
               
                 ATOM 
                 1860 
                 CB 
                 GLU 
                 A 
                 236 
                 95.678 
                 30.980 
                 −8.058 
                 1.00 
                 86.71 
                 C 
               
               
                 ATOM 
                 1861 
                 CG 
                 GLU 
                 A 
                 236 
                 96.901 
                 30.285 
                 −7.479 
                 1.00 
                 87.83 
                 C 
               
               
                 ATOM 
                 1862 
                 CD 
                 GLU 
                 A 
                 236 
                 97.991 
                 30.039 
                 −8.502 
                 1.00 
                 88.15 
                 C 
               
               
                 ATOM 
                 1863 
                 OE1 
                 GLU 
                 A 
                 236 
                 97.673 
                 29.826 
                 −9.691 
                 1.00 
                 90.60 
                 O 
               
               
                 ATOM 
                 1864 
                 OE2 
                 GLU 
                 A 
                 236 
                 99.171 
                 30.051 
                 −8.107 
                 1.00 
                 91.39 
                 O 
               
               
                 ATOM 
                 1865 
                 C 
                 GLU 
                 A 
                 236 
                 94.652 
                 32.977 
                 −9.136 
                 1.00 
                 83.78 
                 C 
               
               
                 ATOM 
                 1866 
                 O 
                 GLU 
                 A 
                 236 
                 93.927 
                 33.542 
                 −8.314 
                 1.00 
                 82.36 
                 O 
               
               
                 ATOM 
                 1867 
                 N 
                 PHE 
                 A 
                 237 
                 94.351 
                 32.889 
                 −10.431 
                 1.00 
                 82.30 
                 N 
               
               
                 ATOM 
                 1868 
                 CA 
                 PHE 
                 A 
                 237 
                 93.163 
                 33.530 
                 −10.991 
                 1.00 
                 79.56 
                 C 
               
               
                 ATOM 
                 1869 
                 CB 
                 PHE 
                 A 
                 237 
                 93.587 
                 34.682 
                 −11.900 
                 1.00 
                 78.27 
                 C 
               
               
                 ATOM 
                 1870 
                 CG 
                 PHE 
                 A 
                 237 
                 94.560 
                 35.626 
                 −11.260 
                 1.00 
                 77.48 
                 C 
               
               
                 ATOM 
                 1871 
                 CD1 
                 PHE 
                 A 
                 237 
                 94.115 
                 36.639 
                 −10.424 
                 1.00 
                 78.26 
                 C 
               
               
                 ATOM 
                 1872 
                 CE1 
                 PHE 
                 A 
                 237 
                 95.011 
                 37.512 
                 −9.830 
                 1.00 
                 79.61 
                 C 
               
               
                 ATOM 
                 1873 
                 CZ 
                 PHE 
                 A 
                 237 
                 96.368 
                 37.378 
                 −10.069 
                 1.00 
                 80.36 
                 C 
               
               
                 ATOM 
                 1874 
                 CE2 
                 PHE 
                 A 
                 237 
                 96.825 
                 36.370 
                 −10.900 
                 1.00 
                 79.83 
                 C 
               
               
                 ATOM 
                 1875 
                 CD2 
                 PHE 
                 A 
                 237 
                 95.922 
                 35.499 
                 −11.489 
                 1.00 
                 78.69 
                 C 
               
               
                 ATOM 
                 1876 
                 C 
                 PHE 
                 A 
                 237 
                 92.275 
                 32.558 
                 −11.763 
                 1.00 
                 79.29 
                 C 
               
               
                 ATOM 
                 1877 
                 O 
                 PHE 
                 A 
                 237 
                 91.539 
                 32.967 
                 −12.664 
                 1.00 
                 81.99 
                 O 
               
               
                 ATOM 
                 1878 
                 N 
                 ASP 
                 A 
                 238 
                 92.327 
                 31.279 
                 −11.400 
                 1.00 
                 77.44 
                 N 
               
               
                 ATOM 
                 1879 
                 CA 
                 ASP 
                 A 
                 238 
                 91.510 
                 30.265 
                 −12.062 
                 1.00 
                 77.10 
                 C 
               
               
                 ATOM 
                 1880 
                 CB 
                 ASP 
                 A 
                 238 
                 91.932 
                 28.856 
                 −11.639 
                 1.00 
                 78.33 
                 C 
               
               
                 ATOM 
                 1881 
                 CG 
                 ASP 
                 A 
                 238 
                 93.362 
                 28.523 
                 −12.033 
                 1.00 
                 79.57 
                 C 
               
               
                 ATOM 
                 1882 
                 OD1 
                 ASP 
                 A 
                 238 
                 94.279 
                 29.312 
                 −11.712 
                 1.00 
                 79.76 
                 O 
               
               
                 ATOM 
                 1883 
                 OD2 
                 ASP 
                 A 
                 238 
                 93.567 
                 27.455 
                 −12.648 
                 1.00 
                 82.19 
                 O 
               
               
                 ATOM 
                 1884 
                 C 
                 ASP 
                 A 
                 238 
                 90.031 
                 30.473 
                 −11.746 
                 1.00 
                 75.52 
                 C 
               
               
                 ATOM 
                 1885 
                 O 
                 ASP 
                 A 
                 238 
                 89.684 
                 31.143 
                 −10.775 
                 1.00 
                 73.58 
                 O 
               
               
                 ATOM 
                 1886 
                 N 
                 ASP 
                 A 
                 239 
                 89.164 
                 29.900 
                 −12.572 
                 1.00 
                 77.44 
                 N 
               
               
                 ATOM 
                 1887 
                 CA 
                 ASP 
                 A 
                 239 
                 87.727 
                 30.036 
                 −12.373 
                 1.00 
                 78.86 
                 C 
               
               
                 ATOM 
                 1888 
                 CB 
                 ASP 
                 A 
                 239 
                 86.955 
                 29.654 
                 −13.642 
                 1.00 
                 81.52 
                 C 
               
               
                 ATOM 
                 1889 
                 CG 
                 ASP 
                 A 
                 239 
                 85.477 
                 30.011 
                 −13.560 
                 1.00 
                 82.95 
                 C 
               
               
                 ATOM 
                 1890 
                 OD1 
                 ASP 
                 A 
                 239 
                 84.643 
                 29.085 
                 −13.509 
                 1.00 
                 78.59 
                 O 
               
               
                 ATOM 
                 1891 
                 OD2 
                 ASP 
                 A 
                 239 
                 85.153 
                 31.218 
                 −13.519 
                 1.00 
                 85.56 
                 O 
               
               
                 ATOM 
                 1892 
                 C 
                 ASP 
                 A 
                 239 
                 87.260 
                 29.164 
                 −11.216 
                 1.00 
                 77.00 
                 C 
               
               
                 ATOM 
                 1893 
                 O 
                 ASP 
                 A 
                 239 
                 87.864 
                 28.137 
                 −10.916 
                 1.00 
                 77.36 
                 O 
               
               
                 ATOM 
                 1894 
                 N 
                 TYR 
                 A 
                 240 
                 86.175 
                 29.599 
                 −10.584 
                 1.00 
                 77.15 
                 N 
               
               
                 ATOM 
                 1895 
                 CA 
                 TYR 
                 A 
                 240 
                 85.514 
                 28.897 
                 −9.484 
                 1.00 
                 78.20 
                 C 
               
               
                 ATOM 
                 1896 
                 CB 
                 TYR 
                 A 
                 240 
                 84.096 
                 29.465 
                 −9.351 
                 1.00 
                 78.56 
                 C 
               
               
                 ATOM 
                 1897 
                 CG 
                 TYR 
                 A 
                 240 
                 83.250 
                 28.928 
                 −8.219 
                 1.00 
                 78.85 
                 C 
               
               
                 ATOM 
                 1898 
                 CD1 
                 TYR 
                 A 
                 240 
                 82.506 
                 27.762 
                 −8.372 
                 1.00 
                 80.37 
                 C 
               
               
                 ATOM 
                 1899 
                 CE1 
                 TYR 
                 A 
                 240 
                 81.712 
                 27.279 
                 −7.344 
                 1.00 
                 81.09 
                 C 
               
               
                 ATOM 
                 1900 
                 CZ 
                 TYR 
                 A 
                 240 
                 81.641 
                 27.975 
                 −6.150 
                 1.00 
                 79.15 
                 C 
               
               
                 ATOM 
                 1901 
                 OH 
                 TYR 
                 A 
                 240 
                 80.854 
                 27.504 
                 −5.126 
                 1.00 
                 80.96 
                 O 
               
               
                 ATOM 
                 1902 
                 CE2 
                 TYR 
                 A 
                 240 
                 82.359 
                 29.141 
                 −5.979 
                 1.00 
                 77.95 
                 C 
               
               
                 ATOM 
                 1903 
                 CD2 
                 TYR 
                 A 
                 240 
                 83.152 
                 29.616 
                 −7.011 
                 1.00 
                 77.64 
                 C 
               
               
                 ATOM 
                 1904 
                 C 
                 TYR 
                 A 
                 240 
                 85.456 
                 27.376 
                 −9.667 
                 1.00 
                 80.18 
                 C 
               
               
                 ATOM 
                 1905 
                 O 
                 TYR 
                 A 
                 240 
                 85.729 
                 26.629 
                 −8.727 
                 1.00 
                 81.92 
                 O 
               
               
                 ATOM 
                 1906 
                 N 
                 ILE 
                 A 
                 241 
                 85.119 
                 26.926 
                 −10.874 
                 1.00 
                 83.74 
                 N 
               
               
                 ATOM 
                 1907 
                 CA 
                 ILE 
                 A 
                 241 
                 84.960 
                 25.487 
                 −11.153 
                 1.00 
                 86.17 
                 C 
               
               
                 ATOM 
                 1908 
                 CB 
                 ILE 
                 A 
                 241 
                 83.893 
                 25.231 
                 −12.245 
                 1.00 
                 88.43 
                 C 
               
               
                 ATOM 
                 1909 
                 CG1 
                 ILE 
                 A 
                 241 
                 84.370 
                 25.716 
                 −13.623 
                 1.00 
                 93.04 
                 C 
               
               
                 ATOM 
                 1910 
                 CD1 
                 ILE 
                 A 
                 241 
                 83.371 
                 25.475 
                 −14.738 
                 1.00 
                 94.29 
                 C 
               
               
                 ATOM 
                 1911 
                 CG2 
                 ILE 
                 A 
                 241 
                 82.582 
                 25.897 
                 −11.854 
                 1.00 
                 88.01 
                 C 
               
               
                 ATOM 
                 1912 
                 C 
                 ILE 
                 A 
                 241 
                 86.254 
                 24.744 
                 −11.523 
                 1.00 
                 83.81 
                 C 
               
               
                 ATOM 
                 1913 
                 O 
                 ILE 
                 A 
                 241 
                 86.244 
                 23.519 
                 −11.653 
                 1.00 
                 82.49 
                 O 
               
               
                 ATOM 
                 1914 
                 N 
                 ALA 
                 A 
                 242 
                 87.356 
                 25.474 
                 −11.682 
                 1.00 
                 81.78 
                 N 
               
               
                 ATOM 
                 1915 
                 CA 
                 ALA 
                 A 
                 242 
                 88.653 
                 24.872 
                 −12.006 
                 1.00 
                 82.72 
                 C 
               
               
                 ATOM 
                 1916 
                 CB 
                 ALA 
                 A 
                 242 
                 89.058 
                 25.243 
                 −13.426 
                 1.00 
                 83.77 
                 C 
               
               
                 ATOM 
                 1917 
                 C 
                 ALA 
                 A 
                 242 
                 89.720 
                 25.330 
                 −11.007 
                 1.00 
                 81.87 
                 C 
               
               
                 ATOM 
                 1918 
                 O 
                 ALA 
                 A 
                 242 
                 90.746 
                 25.886 
                 −11.403 
                 1.00 
                 86.24 
                 O 
               
               
                 ATOM 
                 1919 
                 N 
                 PRO 
                 A 
                 243 
                 89.491 
                 25.078 
                 −9.706 
                 1.00 
                 78.01 
                 N 
               
               
                 ATOM 
                 1920 
                 CA 
                 PRO 
                 A 
                 243 
                 90.380 
                 25.570 
                 −8.659 
                 1.00 
                 76.24 
                 C 
               
               
                 ATOM 
                 1921 
                 CB 
                 PRO 
                 A 
                 243 
                 89.671 
                 25.135 
                 −7.374 
                 1.00 
                 76.42 
                 C 
               
               
                 ATOM 
                 1922 
                 CG 
                 PRO 
                 A 
                 243 
                 88.922 
                 23.922 
                 −7.762 
                 1.00 
                 76.32 
                 C 
               
               
                 ATOM 
                 1923 
                 CD 
                 PRO 
                 A 
                 243 
                 88.454 
                 24.189 
                 −9.159 
                 1.00 
                 77.94 
                 C 
               
               
                 ATOM 
                 1924 
                 C 
                 PRO 
                 A 
                 243 
                 91.775 
                 24.963 
                 −8.688 
                 1.00 
                 76.10 
                 C 
               
               
                 ATOM 
                 1925 
                 O 
                 PRO 
                 A 
                 243 
                 91.943 
                 23.840 
                 −9.163 
                 1.00 
                 79.70 
                 O 
               
               
                 ATOM 
                 1926 
                 N 
                 PRO 
                 A 
                 244 
                 92.774 
                 25.704 
                 −8.180 
                 1.00 
                 75.98 
                 N 
               
               
                 ATOM 
                 1927 
                 CA 
                 PRO 
                 A 
                 244 
                 94.118 
                 25.170 
                 −8.030 
                 1.00 
                 76.31 
                 C 
               
               
                 ATOM 
                 1928 
                 CB 
                 PRO 
                 A 
                 244 
                 94.962 
                 26.420 
                 −7.789 
                 1.00 
                 76.74 
                 C 
               
               
                 ATOM 
                 1929 
                 CG 
                 PRO 
                 A 
                 244 
                 94.036 
                 27.354 
                 −7.101 
                 1.00 
                 78.02 
                 C 
               
               
                 ATOM 
                 1930 
                 CD 
                 PRO 
                 A 
                 244 
                 92.691 
                 27.103 
                 −7.721 
                 1.00 
                 78.51 
                 C 
               
               
                 ATOM 
                 1931 
                 C 
                 PRO 
                 A 
                 244 
                 94.177 
                 24.244 
                 −6.818 
                 1.00 
                 76.54 
                 C 
               
               
                 ATOM 
                 1932 
                 O 
                 PRO 
                 A 
                 244 
                 93.361 
                 24.386 
                 −5.906 
                 1.00 
                 77.43 
                 O 
               
               
                 ATOM 
                 1933 
                 N 
                 PHE 
                 A 
                 245 
                 95.121 
                 23.306 
                 −6.813 
                 1.00 
                 74.44 
                 N 
               
               
                 ATOM 
                 1934 
                 CA 
                 PHE 
                 A 
                 245 
                 95.264 
                 22.362 
                 −5.706 
                 1.00 
                 73.61 
                 C 
               
               
                 ATOM 
                 1935 
                 CB 
                 PHE 
                 A 
                 245 
                 94.775 
                 20.975 
                 −6.115 
                 1.00 
                 74.52 
                 C 
               
               
                 ATOM 
                 1936 
                 CG 
                 PHE 
                 A 
                 245 
                 93.368 
                 20.944 
                 −6.629 
                 1.00 
                 73.98 
                 C 
               
               
                 ATOM 
                 1937 
                 CD1 
                 PHE 
                 A 
                 245 
                 92.323 
                 21.415 
                 −5.855 
                 1.00 
                 74.62 
                 C 
               
               
                 ATOM 
                 1938 
                 CE1 
                 PHE 
                 A 
                 245 
                 91.024 
                 21.367 
                 −6.321 
                 1.00 
                 75.77 
                 C 
               
               
                 ATOM 
                 1939 
                 CZ 
                 PHE 
                 A 
                 245 
                 90.755 
                 20.825 
                 −7.565 
                 1.00 
                 75.22 
                 C 
               
               
                 ATOM 
                 1940 
                 CE2 
                 PHE 
                 A 
                 245 
                 91.788 
                 20.338 
                 −8.340 
                 1.00 
                 74.75 
                 C 
               
               
                 ATOM 
                 1941 
                 CD2 
                 PHE 
                 A 
                 245 
                 93.084 
                 20.393 
                 −7.869 
                 1.00 
                 74.29 
                 C 
               
               
                 ATOM 
                 1942 
                 C 
                 PHE 
                 A 
                 245 
                 96.709 
                 22.221 
                 −5.263 
                 1.00 
                 72.53 
                 C 
               
               
                 ATOM 
                 1943 
                 O 
                 PHE 
                 A 
                 245 
                 97.627 
                 22.606 
                 −5.982 
                 1.00 
                 73.25 
                 O 
               
               
                 ATOM 
                 1944 
                 N 
                 TYR 
                 A 
                 246 
                 96.897 
                 21.653 
                 −4.074 
                 1.00 
                 72.91 
                 N 
               
               
                 ATOM 
                 1945 
                 CA 
                 TYR 
                 A 
                 246 
                 98.229 
                 21.308 
                 −3.579 
                 1.00 
                 72.22 
                 C 
               
               
                 ATOM 
                 1946 
                 CB 
                 TYR 
                 A 
                 246 
                 98.327 
                 21.497 
                 −2.059 
                 1.00 
                 68.60 
                 C 
               
               
                 ATOM 
                 1947 
                 CG 
                 TYR 
                 A 
                 246 
                 98.162 
                 22.946 
                 −1.635 
                 1.00 
                 64.47 
                 C 
               
               
                 ATOM 
                 1948 
                 CD1 
                 TYR 
                 A 
                 246 
                 99.206 
                 23.855 
                 −1.774 
                 1.00 
                 62.58 
                 C 
               
               
                 ATOM 
                 1949 
                 CE1 
                 TYR 
                 A 
                 246 
                 99.059 
                 25.179 
                 −1.400 
                 1.00 
                 61.70 
                 C 
               
               
                 ATOM 
                 1950 
                 CZ 
                 TYR 
                 A 
                 246 
                 97.859 
                 25.611 
                 −0.878 
                 1.00 
                 63.67 
                 C 
               
               
                 ATOM 
                 1951 
                 OH 
                 TYR 
                 A 
                 246 
                 97.704 
                 26.932 
                 −0.505 
                 1.00 
                 65.65 
                 O 
               
               
                 ATOM 
                 1952 
                 CE2 
                 TYR 
                 A 
                 246 
                 96.807 
                 24.728 
                 −0.731 
                 1.00 
                 64.18 
                 C 
               
               
                 ATOM 
                 1953 
                 CD2 
                 TYR 
                 A 
                 246 
                 96.963 
                 23.406 
                 −1.110 
                 1.00 
                 63.71 
                 C 
               
               
                 ATOM 
                 1954 
                 C 
                 TYR 
                 A 
                 246 
                 98.484 
                 19.868 
                 −4.014 
                 1.00 
                 75.37 
                 C 
               
               
                 ATOM 
                 1955 
                 O 
                 TYR 
                 A 
                 246 
                 98.487 
                 18.939 
                 −3.204 
                 1.00 
                 74.50 
                 O 
               
               
                 ATOM 
                 1956 
                 N 
                 ASN 
                 A 
                 247 
                 98.678 
                 19.720 
                 −5.325 
                 1.00 
                 79.83 
                 N 
               
               
                 ATOM 
                 1957 
                 CA 
                 ASN 
                 A 
                 247 
                 98.830 
                 18.434 
                 −6.003 
                 1.00 
                 80.51 
                 C 
               
               
                 ATOM 
                 1958 
                 CB 
                 ASN 
                 A 
                 247 
                 97.544 
                 18.107 
                 −6.774 
                 1.00 
                 80.27 
                 C 
               
               
                 ATOM 
                 1959 
                 CG 
                 ASN 
                 A 
                 247 
                 96.464 
                 17.522 
                 −5.903 
                 1.00 
                 83.93 
                 C 
               
               
                 ATOM 
                 1960 
                 OD1 
                 ASN 
                 A 
                 247 
                 96.733 
                 16.963 
                 −4.840 
                 1.00 
                 93.05 
                 O 
               
               
                 ATOM 
                 1961 
                 ND2 
                 ASN 
                 A 
                 247 
                 95.225 
                 17.621 
                 −6.366 
                 1.00 
                 85.79 
                 N 
               
               
                 ATOM 
                 1962 
                 C 
                 ASN 
                 A 
                 247 
                 99.952 
                 18.480 
                 −7.020 
                 1.00 
                 82.01 
                 C 
               
               
                 ATOM 
                 1963 
                 O 
                 ASN 
                 A 
                 247 
                 100.646 
                 19.491 
                 −7.160 
                 1.00 
                 78.89 
                 O 
               
               
                 ATOM 
                 1964 
                 N 
                 ASP 
                 A 
                 248 
                 100.112 
                 17.371 
                 −7.739 
                 1.00 
                 84.71 
                 N 
               
               
                 ATOM 
                 1965 
                 CA 
                 ASP 
                 A 
                 248 
                 101.017 
                 17.314 
                 −8.880 
                 1.00 
                 84.53 
                 C 
               
               
                 ATOM 
                 1966 
                 CB 
                 ASP 
                 A 
                 248 
                 100.996 
                 15.918 
                 −9.516 
                 1.00 
                 87.09 
                 C 
               
               
                 ATOM 
                 1967 
                 CG 
                 ASP 
                 A 
                 248 
                 101.481 
                 14.828 
                 −8.570 
                 1.00 
                 88.71 
                 C 
               
               
                 ATOM 
                 1968 
                 OD1 
                 ASP 
                 A 
                 248 
                 102.396 
                 15.092 
                 −7.764 
                 1.00 
                 90.98 
                 O 
               
               
                 ATOM 
                 1969 
                 OD2 
                 ASP 
                 A 
                 248 
                 100.952 
                 13.698 
                 −8.642 
                 1.00 
                 92.33 
                 O 
               
               
                 ATOM 
                 1970 
                 C 
                 ASP 
                 A 
                 248 
                 100.591 
                 18.374 
                 −9.902 
                 1.00 
                 81.24 
                 C 
               
               
                 ATOM 
                 1971 
                 O 
                 ASP 
                 A 
                 248 
                 101.433 
                 18.957 
                 −10.579 
                 1.00 
                 81.25 
                 O 
               
               
                 ATOM 
                 1972 
                 N 
                 LEU 
                 A 
                 249 
                 99.286 
                 18.641 
                 −9.978 
                 1.00 
                 77.42 
                 N 
               
               
                 ATOM 
                 1973 
                 CA 
                 LEU 
                 A 
                 249 
                 98.732 
                 19.660 
                 −10.873 
                 1.00 
                 75.67 
                 C 
               
               
                 ATOM 
                 1974 
                 CB 
                 LEU 
                 A 
                 249 
                 97.238 
                 19.847 
                 −10.598 
                 1.00 
                 75.24 
                 C 
               
               
                 ATOM 
                 1975 
                 CG 
                 LEU 
                 A 
                 249 
                 96.473 
                 20.856 
                 −11.463 
                 1.00 
                 74.40 
                 C 
               
               
                 ATOM 
                 1976 
                 CD1 
                 LEU 
                 A 
                 249 
                 96.534 
                 20.491 
                 −12.938 
                 1.00 
                 74.67 
                 C 
               
               
                 ATOM 
                 1977 
                 CD2 
                 LEU 
                 A 
                 249 
                 95.028 
                 20.947 
                 −11.005 
                 1.00 
                 74.24 
                 C 
               
               
                 ATOM 
                 1978 
                 C 
                 LEU 
                 A 
                 249 
                 99.442 
                 21.014 
                 −10.787 
                 1.00 
                 76.45 
                 C 
               
               
                 ATOM 
                 1979 
                 O 
                 LEU 
                 A 
                 249 
                 99.513 
                 21.734 
                 −11.782 
                 1.00 
                 77.11 
                 O 
               
               
                 ATOM 
                 1980 
                 N 
                 TYR 
                 A 
                 250 
                 99.941 
                 21.366 
                 −9.604 
                 1.00 
                 77.44 
                 N 
               
               
                 ATOM 
                 1981 
                 CA 
                 TYR 
                 A 
                 250 
                 100.709 
                 22.604 
                 −9.418 
                 1.00 
                 76.72 
                 C 
               
               
                 ATOM 
                 1982 
                 CB 
                 TYR 
                 A 
                 250 
                 99.971 
                 23.544 
                 −8.460 
                 1.00 
                 76.13 
                 C 
               
               
                 ATOM 
                 1983 
                 CG 
                 TYR 
                 A 
                 250 
                 98.875 
                 24.317 
                 −9.151 
                 1.00 
                 77.89 
                 C 
               
               
                 ATOM 
                 1984 
                 CD1 
                 TYR 
                 A 
                 250 
                 99.041 
                 25.661 
                 −9.470 
                 1.00 
                 78.85 
                 C 
               
               
                 ATOM 
                 1985 
                 CE1 
                 TYR 
                 A 
                 250 
                 98.046 
                 26.370 
                 −10.121 
                 1.00 
                 79.13 
                 C 
               
               
                 ATOM 
                 1986 
                 CZ 
                 TYR 
                 A 
                 250 
                 96.873 
                 25.733 
                 −10.478 
                 1.00 
                 77.99 
                 C 
               
               
                 ATOM 
                 1987 
                 OH 
                 TYR 
                 A 
                 250 
                 95.886 
                 26.441 
                 −11.125 
                 1.00 
                 78.48 
                 O 
               
               
                 ATOM 
                 1988 
                 CE2 
                 TYR 
                 A 
                 250 
                 96.689 
                 24.397 
                 −10.183 
                 1.00 
                 78.51 
                 C 
               
               
                 ATOM 
                 1989 
                 CD2 
                 TYR 
                 A 
                 250 
                 97.690 
                 23.696 
                 −9.527 
                 1.00 
                 78.94 
                 C 
               
               
                 ATOM 
                 1990 
                 C 
                 TYR 
                 A 
                 250 
                 102.139 
                 22.314 
                 −8.949 
                 1.00 
                 77.37 
                 C 
               
               
                 ATOM 
                 1991 
                 O 
                 TYR 
                 A 
                 250 
                 102.786 
                 23.154 
                 −8.319 
                 1.00 
                 79.16 
                 O 
               
               
                 ATOM 
                 1992 
                 N 
                 ASN 
                 A 
                 251 
                 102.627 
                 21.124 
                 −9.302 
                 1.00 
                 75.93 
                 N 
               
               
                 ATOM 
                 1993 
                 CA 
                 ASN 
                 A 
                 251 
                 103.972 
                 20.654 
                 −8.959 
                 1.00 
                 71.67 
                 C 
               
               
                 ATOM 
                 1994 
                 CB 
                 ASN 
                 A 
                 251 
                 105.034 
                 21.535 
                 −9.629 
                 1.00 
                 68.52 
                 C 
               
               
                 ATOM 
                 1995 
                 CG 
                 ASN 
                 A 
                 251 
                 106.359 
                 20.814 
                 −9.825 
                 1.00 
                 66.38 
                 C 
               
               
                 ATOM 
                 1996 
                 OD1 
                 ASN 
                 A 
                 251 
                 106.408 
                 19.585 
                 −9.907 
                 1.00 
                 63.22 
                 O 
               
               
                 ATOM 
                 1997 
                 ND2 
                 ASN 
                 A 
                 251 
                 107.446 
                 21.583 
                 −9.909 
                 1.00 
                 65.44 
                 N 
               
               
                 ATOM 
                 1998 
                 C 
                 ASN 
                 A 
                 251 
                 104.234 
                 20.545 
                 −7.451 
                 1.00 
                 72.30 
                 C 
               
               
                 ATOM 
                 1999 
                 O 
                 ASN 
                 A 
                 251 
                 105.375 
                 20.673 
                 −6.999 
                 1.00 
                 71.50 
                 O 
               
               
                 ATOM 
                 2000 
                 N 
                 PHE 
                 A 
                 252 
                 103.179 
                 20.306 
                 −6.678 
                 1.00 
                 72.57 
                 N 
               
               
                 ATOM 
                 2001 
                 CA 
                 PHE 
                 A 
                 252 
                 103.325 
                 20.072 
                 −5.247 
                 1.00 
                 73.19 
                 C 
               
               
                 ATOM 
                 2002 
                 CB 
                 PHE 
                 A 
                 252 
                 102.166 
                 20.686 
                 −4.453 
                 1.00 
                 71.29 
                 C 
               
               
                 ATOM 
                 2003 
                 CG 
                 PHE 
                 A 
                 252 
                 102.198 
                 22.192 
                 −4.393 
                 1.00 
                 70.12 
                 C 
               
               
                 ATOM 
                 2004 
                 CD1 
                 PHE 
                 A 
                 252 
                 103.206 
                 22.851 
                 −3.699 
                 1.00 
                 69.07 
                 C 
               
               
                 ATOM 
                 2005 
                 CE1 
                 PHE 
                 A 
                 252 
                 103.239 
                 24.236 
                 −3.636 
                 1.00 
                 67.34 
                 C 
               
               
                 ATOM 
                 2006 
                 CZ 
                 PHE 
                 A 
                 252 
                 102.253 
                 24.980 
                 −4.258 
                 1.00 
                 66.91 
                 C 
               
               
                 ATOM 
                 2007 
                 CE2 
                 PHE 
                 A 
                 252 
                 101.236 
                 24.338 
                 −4.944 
                 1.00 
                 67.96 
                 C 
               
               
                 ATOM 
                 2008 
                 CD2 
                 PHE 
                 A 
                 252 
                 101.209 
                 22.952 
                 −5.006 
                 1.00 
                 69.30 
                 C 
               
               
                 ATOM 
                 2009 
                 C 
                 PHE 
                 A 
                 252 
                 103.407 
                 18.563 
                 −5.028 
                 1.00 
                 75.80 
                 C 
               
               
                 ATOM 
                 2010 
                 O 
                 PHE 
                 A 
                 252 
                 102.383 
                 17.886 
                 −4.913 
                 1.00 
                 72.23 
                 O 
               
               
                 ATOM 
                 2011 
                 N 
                 LYS 
                 A 
                 253 
                 104.634 
                 18.045 
                 −4.987 
                 1.00 
                 81.32 
                 N 
               
               
                 ATOM 
                 2012 
                 CA 
                 LYS 
                 A 
                 253 
                 104.864 
                 16.615 
                 −4.785 
                 1.00 
                 85.77 
                 C 
               
               
                 ATOM 
                 2013 
                 CB 
                 LYS 
                 A 
                 253 
                 106.331 
                 16.241 
                 −5.026 
                 1.00 
                 92.98 
                 C 
               
               
                 ATOM 
                 2014 
                 CG 
                 LYS 
                 A 
                 253 
                 106.767 
                 16.408 
                 −6.472 
                 1.00 
                 99.97 
                 C 
               
               
                 ATOM 
                 2015 
                 CD 
                 LYS 
                 A 
                 253 
                 108.226 
                 16.049 
                 −6.675 
                 1.00 
                 106.09 
                 C 
               
               
                 ATOM 
                 2016 
                 CE 
                 LYS 
                 A 
                 253 
                 109.129 
                 17.247 
                 −6.439 
                 1.00 
                 111.70 
                 C 
               
               
                 ATOM 
                 2017 
                 NZ 
                 LYS 
                 A 
                 253 
                 110.541 
                 16.971 
                 −6.825 
                 1.00 
                 115.13 
                 N 
               
               
                 ATOM 
                 2018 
                 C 
                 LYS 
                 A 
                 253 
                 104.424 
                 16.191 
                 −3.387 
                 1.00 
                 86.29 
                 C 
               
               
                 ATOM 
                 2019 
                 O 
                 LYS 
                 A 
                 253 
                 104.542 
                 16.954 
                 −2.421 
                 1.00 
                 88.83 
                 O 
               
               
                 ATOM 
                 2020 
                 N 
                 ASP 
                 A 
                 254 
                 103.890 
                 14.979 
                 −3.291 
                 1.00 
                 84.69 
                 N 
               
               
                 ATOM 
                 2021 
                 CA 
                 ASP 
                 A 
                 254 
                 103.447 
                 14.441 
                 −2.014 
                 1.00 
                 79.32 
                 C 
               
               
                 ATOM 
                 2022 
                 CB 
                 ASP 
                 A 
                 254 
                 102.777 
                 13.076 
                 −2.216 
                 1.00 
                 79.03 
                 C 
               
               
                 ATOM 
                 2023 
                 CG 
                 ASP 
                 A 
                 254 
                 101.821 
                 12.712 
                 −1.095 
                 1.00 
                 79.95 
                 C 
               
               
                 ATOM 
                 2024 
                 OD1 
                 ASP 
                 A 
                 254 
                 101.391 
                 13.611 
                 −0.345 
                 1.00 
                 79.56 
                 O 
               
               
                 ATOM 
                 2025 
                 OD2 
                 ASP 
                 A 
                 254 
                 101.476 
                 11.517 
                 −0.979 
                 1.00 
                 83.79 
                 O 
               
               
                 ATOM 
                 2026 
                 C 
                 ASP 
                 A 
                 254 
                 104.684 
                 14.321 
                 −1.131 
                 1.00 
                 77.94 
                 C 
               
               
                 ATOM 
                 2027 
                 O 
                 ASP 
                 A 
                 254 
                 105.735 
                 13.878 
                 −1.592 
                 1.00 
                 77.26 
                 O 
               
               
                 ATOM 
                 2028 
                 N 
                 GLY 
                 A 
                 255 
                 104.570 
                 14.750 
                 0.122 
                 1.00 
                 77.82 
                 N 
               
               
                 ATOM 
                 2029 
                 CA 
                 GLY 
                 A 
                 255 
                 105.690 
                 14.703 
                 1.061 
                 1.00 
                 75.19 
                 C 
               
               
                 ATOM 
                 2030 
                 C 
                 GLY 
                 A 
                 255 
                 106.428 
                 16.024 
                 1.162 
                 1.00 
                 73.47 
                 C 
               
               
                 ATOM 
                 2031 
                 O 
                 GLY 
                 A 
                 255 
                 105.882 
                 17.078 
                 0.847 
                 1.00 
                 73.15 
                 O 
               
               
                 ATOM 
                 2032 
                 N 
                 ALA 
                 A 
                 256 
                 107.681 
                 15.961 
                 1.599 
                 1.00 
                 73.11 
                 N 
               
               
                 ATOM 
                 2033 
                 CA 
                 ALA 
                 A 
                 256 
                 108.483 
                 17.159 
                 1.825 
                 1.00 
                 73.60 
                 C 
               
               
                 ATOM 
                 2034 
                 CB 
                 ALA 
                 A 
                 256 
                 109.684 
                 16.829 
                 2.703 
                 1.00 
                 72.94 
                 C 
               
               
                 ATOM 
                 2035 
                 C 
                 ALA 
                 A 
                 256 
                 108.948 
                 17.803 
                 0.522 
                 1.00 
                 74.79 
                 C 
               
               
                 ATOM 
                 2036 
                 O 
                 ALA 
                 A 
                 256 
                 109.271 
                 17.110 
                 −0.443 
                 1.00 
                 75.91 
                 O 
               
               
                 ATOM 
                 2037 
                 N 
                 GLN 
                 A 
                 257 
                 108.985 
                 19.132 
                 0.514 
                 1.00 
                 74.46 
                 N 
               
               
                 ATOM 
                 2038 
                 CA 
                 GLN 
                 A 
                 257 
                 109.469 
                 19.893 
                 −0.628 
                 1.00 
                 74.65 
                 C 
               
               
                 ATOM 
                 2039 
                 CB 
                 GLN 
                 A 
                 257 
                 108.696 
                 21.213 
                 −0.770 
                 1.00 
                 74.41 
                 C 
               
               
                 ATOM 
                 2040 
                 CG 
                 GLN 
                 A 
                 257 
                 107.178 
                 21.068 
                 −0.734 
                 1.00 
                 74.48 
                 C 
               
               
                 ATOM 
                 2041 
                 CD 
                 GLN 
                 A 
                 257 
                 106.627 
                 20.175 
                 −1.841 
                 1.00 
                 75.54 
                 C 
               
               
                 ATOM 
                 2042 
                 OE1 
                 GLN 
                 A 
                 257 
                 106.881 
                 20.398 
                 −3.028 
                 1.00 
                 72.96 
                 O 
               
               
                 ATOM 
                 2043 
                 NE2 
                 GLN 
                 A 
                 257 
                 105.852 
                 19.169 
                 −1.456 
                 1.00 
                 76.19 
                 N 
               
               
                 ATOM 
                 2044 
                 C 
                 GLN 
                 A 
                 257 
                 110.958 
                 20.148 
                 −0.401 
                 1.00 
                 75.86 
                 C 
               
               
                 ATOM 
                 2045 
                 O 
                 GLN 
                 A 
                 257 
                 111.344 
                 21.135 
                 0.226 
                 1.00 
                 78.46 
                 O 
               
               
                 ATOM 
                 2046 
                 N 
                 ASN 
                 A 
                 258 
                 111.786 
                 19.244 
                 −0.918 
                 1.00 
                 77.15 
                 N 
               
               
                 ATOM 
                 2047 
                 CA 
                 ASN 
                 A 
                 258 
                 113.235 
                 19.270 
                 −0.685 
                 1.00 
                 78.64 
                 C 
               
               
                 ATOM 
                 2048 
                 CB 
                 ASN 
                 A 
                 258 
                 113.801 
                 17.857 
                 −0.862 
                 1.00 
                 79.34 
                 C 
               
               
                 ATOM 
                 2049 
                 CG 
                 ASN 
                 A 
                 258 
                 113.222 
                 16.867 
                 0.135 
                 1.00 
                 80.33 
                 C 
               
               
                 ATOM 
                 2050 
                 OD1 
                 ASN 
                 A 
                 258 
                 112.547 
                 15.911 
                 −0.245 
                 1.00 
                 81.10 
                 O 
               
               
                 ATOM 
                 2051 
                 ND2 
                 ASN 
                 A 
                 258 
                 113.475 
                 17.098 
                 1.417 
                 1.00 
                 80.45 
                 N 
               
               
                 ATOM 
                 2052 
                 C 
                 ASN 
                 A 
                 258 
                 114.042 
                 20.244 
                 −1.549 
                 1.00 
                 79.55 
                 C 
               
               
                 ATOM 
                 2053 
                 O 
                 ASN 
                 A 
                 258 
                 115.225 
                 20.467 
                 −1.285 
                 1.00 
                 79.77 
                 O 
               
               
                 ATOM 
                 2054 
                 N 
                 ASP 
                 A 
                 259 
                 113.409 
                 20.832 
                 −2.560 
                 1.00 
                 81.95 
                 N 
               
               
                 ATOM 
                 2055 
                 CA 
                 ASP 
                 A 
                 259 
                 114.106 
                 21.715 
                 −3.508 
                 1.00 
                 84.57 
                 C 
               
               
                 ATOM 
                 2056 
                 CB 
                 ASP 
                 A 
                 259 
                 113.758 
                 21.302 
                 −4.946 
                 1.00 
                 85.64 
                 C 
               
               
                 ATOM 
                 2057 
                 CG 
                 ASP 
                 A 
                 259 
                 112.263 
                 21.364 
                 −5.237 
                 1.00 
                 86.82 
                 C 
               
               
                 ATOM 
                 2058 
                 OD1 
                 ASP 
                 A 
                 259 
                 111.458 
                 21.428 
                 −4.282 
                 1.00 
                 84.66 
                 O 
               
               
                 ATOM 
                 2059 
                 OD2 
                 ASP 
                 A 
                 259 
                 111.893 
                 21.328 
                 −6.427 
                 1.00 
                 87.99 
                 O 
               
               
                 ATOM 
                 2060 
                 C 
                 ASP 
                 A 
                 259 
                 113.808 
                 23.204 
                 −3.304 
                 1.00 
                 84.43 
                 C 
               
               
                 ATOM 
                 2061 
                 O 
                 ASP 
                 A 
                 259 
                 113.875 
                 23.990 
                 −4.254 
                 1.00 
                 89.08 
                 O 
               
               
                 ATOM 
                 2062 
                 N 
                 ILE 
                 A 
                 260 
                 113.514 
                 23.590 
                 −2.064 
                 1.00 
                 81.70 
                 N 
               
               
                 ATOM 
                 2063 
                 CA 
                 ILE 
                 A 
                 260 
                 113.126 
                 24.971 
                 −1.751 
                 1.00 
                 79.45 
                 C 
               
               
                 ATOM 
                 2064 
                 CB 
                 ILE 
                 A 
                 260 
                 112.008 
                 25.012 
                 −0.679 
                 1.00 
                 78.65 
                 C 
               
               
                 ATOM 
                 2065 
                 CG1 
                 ILE 
                 A 
                 260 
                 112.502 
                 24.469 
                 0.671 
                 1.00 
                 79.64 
                 C 
               
               
                 ATOM 
                 2066 
                 CD1 
                 ILE 
                 A 
                 260 
                 111.509 
                 24.642 
                 1.801 
                 1.00 
                 79.25 
                 C 
               
               
                 ATOM 
                 2067 
                 CG2 
                 ILE 
                 A 
                 260 
                 110.794 
                 24.227 
                 −1.154 
                 1.00 
                 78.74 
                 C 
               
               
                 ATOM 
                 2068 
                 C 
                 ILE 
                 A 
                 260 
                 114.287 
                 25.851 
                 −1.286 
                 1.00 
                 78.23 
                 C 
               
               
                 ATOM 
                 2069 
                 O 
                 ILE 
                 A 
                 260 
                 114.076 
                 27.007 
                 −0.919 
                 1.00 
                 78.94 
                 O 
               
               
                 ATOM 
                 2070 
                 N 
                 PHE 
                 A 
                 261 
                 115.505 
                 25.319 
                 −1.321 
                 1.00 
                 78.47 
                 N 
               
               
                 ATOM 
                 2071 
                 CA 
                 PHE 
                 A 
                 261 
                 116.668 
                 26.030 
                 −0.788 
                 1.00 
                 81.03 
                 C 
               
               
                 ATOM 
                 2072 
                 CB 
                 PHE 
                 A 
                 261 
                 117.508 
                 25.080 
                 0.067 
                 1.00 
                 79.65 
                 C 
               
               
                 ATOM 
                 2073 
                 CG 
                 PHE 
                 A 
                 261 
                 116.687 
                 24.280 
                 1.040 
                 1.00 
                 77.23 
                 C 
               
               
                 ATOM 
                 2074 
                 CD1 
                 PHE 
                 A 
                 261 
                 116.206 
                 24.862 
                 2.201 
                 1.00 
                 76.79 
                 C 
               
               
                 ATOM 
                 2075 
                 CE1 
                 PHE 
                 A 
                 261 
                 115.435 
                 24.136 
                 3.089 
                 1.00 
                 75.75 
                 C 
               
               
                 ATOM 
                 2076 
                 CZ 
                 PHE 
                 A 
                 261 
                 115.130 
                 22.814 
                 2.818 
                 1.00 
                 75.19 
                 C 
               
               
                 ATOM 
                 2077 
                 CE2 
                 PHE 
                 A 
                 261 
                 115.597 
                 22.224 
                 1.660 
                 1.00 
                 75.46 
                 C 
               
               
                 ATOM 
                 2078 
                 CD2 
                 PHE 
                 A 
                 261 
                 116.367 
                 22.957 
                 0.776 
                 1.00 
                 76.57 
                 C 
               
               
                 ATOM 
                 2079 
                 C 
                 PHE 
                 A 
                 261 
                 117.507 
                 26.667 
                 −1.884 
                 1.00 
                 83.24 
                 C 
               
               
                 ATOM 
                 2080 
                 O 
                 PHE 
                 A 
                 261 
                 117.356 
                 26.345 
                 −3.063 
                 1.00 
                 86.36 
                 O 
               
               
                 ATOM 
                 2081 
                 N 
                 VAL 
                 A 
                 262 
                 118.393 
                 27.575 
                 −1.481 
                 1.00 
                 86.71 
                 N 
               
               
                 ATOM 
                 2082 
                 CA 
                 VAL 
                 A 
                 262 
                 119.223 
                 28.325 
                 −2.422 
                 1.00 
                 88.45 
                 C 
               
               
                 ATOM 
                 2083 
                 CB 
                 VAL 
                 A 
                 262 
                 120.044 
                 29.424 
                 −1.709 
                 1.00 
                 89.79 
                 C 
               
               
                 ATOM 
                 2084 
                 CG1 
                 VAL 
                 A 
                 262 
                 120.955 
                 30.146 
                 −2.697 
                 1.00 
                 91.60 
                 C 
               
               
                 ATOM 
                 2085 
                 CG2 
                 VAL 
                 A 
                 262 
                 119.120 
                 30.418 
                 −1.016 
                 1.00 
                 90.85 
                 C 
               
               
                 ATOM 
                 2086 
                 C 
                 VAL 
                 A 
                 262 
                 120.166 
                 27.404 
                 −3.198 
                 1.00 
                 90.80 
                 C 
               
               
                 ATOM 
                 2087 
                 O 
                 VAL 
                 A 
                 262 
                 120.316 
                 27.547 
                 −4.413 
                 1.00 
                 95.70 
                 O 
               
               
                 ATOM 
                 2088 
                 N 
                 ASP 
                 A 
                 263 
                 120.784 
                 26.457 
                 −2.497 
                 1.00 
                 90.45 
                 N 
               
               
                 ATOM 
                 2089 
                 CA 
                 ASP 
                 A 
                 263 
                 121.726 
                 25.519 
                 −3.118 
                 1.00 
                 88.68 
                 C 
               
               
                 ATOM 
                 2090 
                 CB 
                 ASP 
                 A 
                 263 
                 122.763 
                 25.043 
                 −2.087 
                 1.00 
                 89.04 
                 C 
               
               
                 ATOM 
                 2091 
                 CG 
                 ASP 
                 A 
                 263 
                 122.158 
                 24.179 
                 −0.984 
                 1.00 
                 88.58 
                 C 
               
               
                 ATOM 
                 2092 
                 OD1 
                 ASP 
                 A 
                 263 
                 120.943 
                 24.289 
                 −0.721 
                 1.00 
                 89.30 
                 O 
               
               
                 ATOM 
                 2093 
                 OD2 
                 ASP 
                 A 
                 263 
                 122.909 
                 23.391 
                 −0.373 
                 1.00 
                 89.57 
                 O 
               
               
                 ATOM 
                 2094 
                 C 
                 ASP 
                 A 
                 263 
                 121.055 
                 24.306 
                 −3.779 
                 1.00 
                 87.09 
                 C 
               
               
                 ATOM 
                 2095 
                 O 
                 ASP 
                 A 
                 263 
                 121.750 
                 23.446 
                 −4.325 
                 1.00 
                 85.49 
                 O 
               
               
                 ATOM 
                 2096 
                 N 
                 SER 
                 A 
                 264 
                 119.723 
                 24.235 
                 −3.731 
                 1.00 
                 87.15 
                 N 
               
               
                 ATOM 
                 2097 
                 CA 
                 SER 
                 A 
                 264 
                 118.981 
                 23.097 
                 −4.287 
                 1.00 
                 87.74 
                 C 
               
               
                 ATOM 
                 2098 
                 CB 
                 SER 
                 A 
                 264 
                 117.471 
                 23.291 
                 −4.125 
                 1.00 
                 91.73 
                 C 
               
               
                 ATOM 
                 2099 
                 OG 
                 SER 
                 A 
                 264 
                 117.102 
                 23.275 
                 −2.756 
                 1.00 
                 94.76 
                 O 
               
               
                 ATOM 
                 2100 
                 C 
                 SER 
                 A 
                 264 
                 119.312 
                 22.849 
                 −5.749 
                 1.00 
                 85.13 
                 C 
               
               
                 ATOM 
                 2101 
                 O 
                 SER 
                 A 
                 264 
                 119.709 
                 21.745 
                 −6.108 
                 1.00 
                 82.83 
                 O 
               
               
                 ATOM 
                 2102 
                 N 
                 TYR 
                 A 
                 265 
                 119.149 
                 23.876 
                 −6.579 
                 1.00 
                 86.01 
                 N 
               
               
                 ATOM 
                 2103 
                 CA 
                 TYR 
                 A 
                 265 
                 119.461 
                 23.775 
                 −8.008 
                 1.00 
                 87.83 
                 C 
               
               
                 ATOM 
                 2104 
                 CB 
                 TYR 
                 A 
                 265 
                 118.352 
                 24.418 
                 −8.842 
                 1.00 
                 84.66 
                 C 
               
               
                 ATOM 
                 2105 
                 CG 
                 TYR 
                 A 
                 265 
                 117.039 
                 23.670 
                 −8.788 
                 1.00 
                 81.02 
                 C 
               
               
                 ATOM 
                 2106 
                 CD1 
                 TYR 
                 A 
                 265 
                 116.038 
                 24.033 
                 −7.890 
                 1.00 
                 80.85 
                 C 
               
               
                 ATOM 
                 2107 
                 CE1 
                 TYR 
                 A 
                 265 
                 114.836 
                 23.343 
                 −7.840 
                 1.00 
                 78.37 
                 C 
               
               
                 ATOM 
                 2108 
                 CZ 
                 TYR 
                 A 
                 265 
                 114.629 
                 22.274 
                 −8.691 
                 1.00 
                 77.16 
                 C 
               
               
                 ATOM 
                 2109 
                 OH 
                 TYR 
                 A 
                 265 
                 113.448 
                 21.578 
                 −8.654 
                 1.00 
                 73.76 
                 O 
               
               
                 ATOM 
                 2110 
                 CE2 
                 TYR 
                 A 
                 265 
                 115.605 
                 21.897 
                 −9.589 
                 1.00 
                 77.96 
                 C 
               
               
                 ATOM 
                 2111 
                 CD2 
                 TYR 
                 A 
                 265 
                 116.801 
                 22.592 
                 −9.633 
                 1.00 
                 79.46 
                 C 
               
               
                 ATOM 
                 2112 
                 C 
                 TYR 
                 A 
                 265 
                 120.810 
                 24.444 
                 −8.309 
                 1.00 
                 93.04 
                 C 
               
               
                 ATOM 
                 2113 
                 O 
                 TYR 
                 A 
                 265 
                 120.899 
                 25.672 
                 −8.296 
                 1.00 
                 95.54 
                 O 
               
               
                 ATOM 
                 2114 
                 N 
                 PRO 
                 A 
                 266 
                 121.863 
                 23.643 
                 −8.588 
                 1.00 
                 97.30 
                 N 
               
               
                 ATOM 
                 2115 
                 CA 
                 PRO 
                 A 
                 266 
                 123.201 
                 24.199 
                 −8.834 
                 1.00 
                 98.80 
                 C 
               
               
                 ATOM 
                 2116 
                 CB 
                 PRO 
                 A 
                 266 
                 124.093 
                 22.954 
                 −8.953 
                 1.00 
                 99.77 
                 C 
               
               
                 ATOM 
                 2117 
                 CG 
                 PRO 
                 A 
                 266 
                 123.288 
                 21.837 
                 −8.389 
                 1.00 
                 99.49 
                 C 
               
               
                 ATOM 
                 2118 
                 CD 
                 PRO 
                 A 
                 266 
                 121.873 
                 22.178 
                 −8.724 
                 1.00 
                 98.32 
                 C 
               
               
                 ATOM 
                 2119 
                 C 
                 PRO 
                 A 
                 266 
                 123.274 
                 25.015 
                 −10.113 
                 1.00 
                 99.63 
                 C 
               
               
                 ATOM 
                 2120 
                 O 
                 PRO 
                 A 
                 266 
                 123.742 
                 26.152 
                 −10.089 
                 1.00 
                 100.28 
                 O 
               
               
                 ATOM 
                 2121 
                 N 
                 ASP 
                 A 
                 267 
                 122.797 
                 24.431 
                 −11.210 
                 1.00 
                 102.03 
                 N 
               
               
                 ATOM 
                 2122 
                 CA 
                 ASP 
                 A 
                 267 
                 122.783 
                 25.090 
                 −12.511 
                 1.00 
                 104.39 
                 C 
               
               
                 ATOM 
                 2123 
                 CB 
                 ASP 
                 A 
                 267 
                 122.805 
                 24.049 
                 −13.637 
                 1.00 
                 107.27 
                 C 
               
               
                 ATOM 
                 2124 
                 CG 
                 ASP 
                 A 
                 267 
                 124.012 
                 23.135 
                 −13.566 
                 1.00 
                 110.11 
                 C 
               
               
                 ATOM 
                 2125 
                 OD1 
                 ASP 
                 A 
                 267 
                 125.147 
                 23.647 
                 −13.457 
                 1.00 
                 111.81 
                 O 
               
               
                 ATOM 
                 2126 
                 OD2 
                 ASP 
                 A 
                 267 
                 123.821 
                 21.904 
                 −13.637 
                 1.00 
                 110.35 
                 O 
               
               
                 ATOM 
                 2127 
                 C 
                 ASP 
                 A 
                 267 
                 121.564 
                 26.002 
                 −12.678 
                 1.00 
                 103.12 
                 C 
               
               
                 ATOM 
                 2128 
                 O 
                 ASP 
                 A 
                 267 
                 121.354 
                 26.534 
                 −13.764 
                 1.00 
                 102.02 
                 O 
               
               
                 ATOM 
                 2129 
                 N 
                 GLY 
                 A 
                 268 
                 120.760 
                 26.172 
                 −11.625 
                 1.00 
                 101.76 
                 N 
               
               
                 ATOM 
                 2130 
                 CA 
                 GLY 
                 A 
                 268 
                 119.619 
                 27.079 
                 −11.662 
                 1.00 
                 100.79 
                 C 
               
               
                 ATOM 
                 2131 
                 C 
                 GLY 
                 A 
                 268 
                 118.421 
                 26.487 
                 −12.372 
                 1.00 
                 100.45 
                 C 
               
               
                 ATOM 
                 2132 
                 O 
                 GLY 
                 A 
                 268 
                 118.362 
                 25.281 
                 −12.615 
                 1.00 
                 101.51 
                 O 
               
               
                 ATOM 
                 2133 
                 N 
                 ILE 
                 A 
                 269 
                 117.471 
                 27.354 
                 −12.712 
                 1.00 
                 99.07 
                 N 
               
               
                 ATOM 
                 2134 
                 CA 
                 ILE 
                 A 
                 269 
                 116.263 
                 26.968 
                 −13.431 
                 1.00 
                 97.44 
                 C 
               
               
                 ATOM 
                 2135 
                 CB 
                 ILE 
                 A 
                 269 
                 114.996 
                 27.165 
                 −12.561 
                 1.00 
                 97.79 
                 C 
               
               
                 ATOM 
                 2136 
                 CG1 
                 ILE 
                 A 
                 269 
                 115.128 
                 26.365 
                 −11.255 
                 1.00 
                 96.99 
                 C 
               
               
                 ATOM 
                 2137 
                 CD1 
                 ILE 
                 A 
                 269 
                 115.244 
                 27.208 
                 −10.004 
                 1.00 
                 97.80 
                 C 
               
               
                 ATOM 
                 2138 
                 CG2 
                 ILE 
                 A 
                 269 
                 113.731 
                 26.752 
                 −13.309 
                 1.00 
                 99.53 
                 C 
               
               
                 ATOM 
                 2139 
                 C 
                 ILE 
                 A 
                 269 
                 116.176 
                 27.798 
                 −14.713 
                 1.00 
                 97.53 
                 C 
               
               
                 ATOM 
                 2140 
                 O 
                 ILE 
                 A 
                 269 
                 115.593 
                 28.878 
                 −14.708 
                 1.00 
                 98.28 
                 O 
               
               
                 ATOM 
                 2141 
                 N 
                 PRO 
                 A 
                 270 
                 116.793 
                 27.312 
                 −15.808 
                 1.00 
                 98.11 
                 N 
               
               
                 ATOM 
                 2142 
                 CA 
                 PRO 
                 A 
                 270 
                 116.708 
                 27.974 
                 −17.115 
                 1.00 
                 98.64 
                 C 
               
               
                 ATOM 
                 2143 
                 CB 
                 PRO 
                 A 
                 270 
                 117.383 
                 26.973 
                 −18.050 
                 1.00 
                 99.56 
                 C 
               
               
                 ATOM 
                 2144 
                 CG 
                 PRO 
                 A 
                 270 
                 118.402 
                 26.311 
                 −17.193 
                 1.00 
                 100.10 
                 C 
               
               
                 ATOM 
                 2145 
                 CD 
                 PRO 
                 A 
                 270 
                 117.822 
                 26.255 
                 −15.806 
                 1.00 
                 99.54 
                 C 
               
               
                 ATOM 
                 2146 
                 C 
                 PRO 
                 A 
                 270 
                 115.277 
                 28.264 
                 −17.590 
                 1.00 
                 97.88 
                 C 
               
               
                 ATOM 
                 2147 
                 O 
                 PRO 
                 A 
                 270 
                 115.063 
                 29.227 
                 −18.329 
                 1.00 
                 99.51 
                 O 
               
               
                 ATOM 
                 2148 
                 N 
                 LEU 
                 A 
                 271 
                 114.317 
                 27.437 
                 −17.170 
                 1.00 
                 95.54 
                 N 
               
               
                 ATOM 
                 2149 
                 CA 
                 LEU 
                 A 
                 271 
                 112.901 
                 27.631 
                 −17.509 
                 1.00 
                 95.53 
                 C 
               
               
                 ATOM 
                 2150 
                 CB 
                 LEU 
                 A 
                 271 
                 112.035 
                 26.515 
                 −16.919 
                 1.00 
                 93.02 
                 C 
               
               
                 ATOM 
                 2151 
                 CG 
                 LEU 
                 A 
                 271 
                 111.789 
                 25.274 
                 −17.775 
                 1.00 
                 91.39 
                 C 
               
               
                 ATOM 
                 2152 
                 CD1 
                 LEU 
                 A 
                 271 
                 113.066 
                 24.535 
                 −18.101 
                 1.00 
                 89.61 
                 C 
               
               
                 ATOM 
                 2153 
                 CD2 
                 LEU 
                 A 
                 271 
                 110.834 
                 24.345 
                 −17.046 
                 1.00 
                 93.51 
                 C 
               
               
                 ATOM 
                 2154 
                 C 
                 LEU 
                 A 
                 271 
                 112.338 
                 28.975 
                 −17.055 
                 1.00 
                 100.00 
                 C 
               
               
                 ATOM 
                 2155 
                 O 
                 LEU 
                 A 
                 271 
                 111.328 
                 29.430 
                 −17.586 
                 1.00 
                 103.24 
                 O 
               
               
                 ATOM 
                 2156 
                 N 
                 GLU 
                 A 
                 272 
                 112.974 
                 29.598 
                 −16.068 
                 1.00 
                 105.60 
                 N 
               
               
                 ATOM 
                 2157 
                 CA 
                 GLU 
                 A 
                 272 
                 112.547 
                 30.912 
                 −15.595 
                 1.00 
                 111.95 
                 C 
               
               
                 ATOM 
                 2158 
                 CB 
                 GLU 
                 A 
                 272 
                 113.237 
                 31.255 
                 −14.272 
                 1.00 
                 115.04 
                 C 
               
               
                 ATOM 
                 2159 
                 CG 
                 GLU 
                 A 
                 272 
                 112.796 
                 30.355 
                 −13.123 
                 1.00 
                 115.05 
                 C 
               
               
                 ATOM 
                 2160 
                 CD 
                 GLU 
                 A 
                 272 
                 113.542 
                 30.617 
                 −11.825 
                 1.00 
                 116.07 
                 C 
               
               
                 ATOM 
                 2161 
                 OE1 
                 GLU 
                 A 
                 272 
                 114.662 
                 31.175 
                 −11.865 
                 1.00 
                 115.23 
                 O 
               
               
                 ATOM 
                 2162 
                 OE2 
                 GLU 
                 A 
                 272 
                 113.005 
                 30.252 
                 −10.757 
                 1.00 
                 113.02 
                 O 
               
               
                 ATOM 
                 2163 
                 C 
                 GLU 
                 A 
                 272 
                 112.778 
                 32.014 
                 −16.640 
                 1.00 
                 114.41 
                 C 
               
               
                 ATOM 
                 2164 
                 O 
                 GLU 
                 A 
                 272 
                 112.257 
                 33.118 
                 −16.497 
                 1.00 
                 115.45 
                 O 
               
               
                 ATOM 
                 2165 
                 N 
                 GLN 
                 A 
                 273 
                 113.557 
                 31.715 
                 −17.681 
                 1.00 
                 118.50 
                 N 
               
               
                 ATOM 
                 2166 
                 CA 
                 GLN 
                 A 
                 273 
                 113.747 
                 32.640 
                 −18.800 
                 1.00 
                 125.42 
                 C 
               
               
                 ATOM 
                 2167 
                 CB 
                 GLN 
                 A 
                 273 
                 114.790 
                 32.092 
                 −19.781 
                 1.00 
                 125.39 
                 C 
               
               
                 ATOM 
                 2168 
                 CG 
                 GLN 
                 A 
                 273 
                 115.017 
                 32.962 
                 −21.010 
                 1.00 
                 125.94 
                 C 
               
               
                 ATOM 
                 2169 
                 CD 
                 GLN 
                 A 
                 273 
                 116.022 
                 32.366 
                 −21.977 
                 1.00 
                 127.86 
                 C 
               
               
                 ATOM 
                 2170 
                 OE1 
                 GLN 
                 A 
                 273 
                 115.685 
                 32.049 
                 −23.118 
                 1.00 
                 127.00 
                 O 
               
               
                 ATOM 
                 2171 
                 NE2 
                 GLN 
                 A 
                 273 
                 117.259 
                 32.198 
                 −21.522 
                 1.00 
                 129.88 
                 N 
               
               
                 ATOM 
                 2172 
                 C 
                 GLN 
                 A 
                 273 
                 112.422 
                 32.879 
                 −19.529 
                 1.00 
                 132.03 
                 C 
               
               
                 ATOM 
                 2173 
                 O 
                 GLN 
                 A 
                 273 
                 112.161 
                 33.984 
                 −20.010 
                 1.00 
                 133.87 
                 O 
               
               
                 ATOM 
                 2174 
                 N 
                 LYS 
                 A 
                 274 
                 111.592 
                 31.840 
                 −19.601 
                 1.00 
                 138.59 
                 N 
               
               
                 ATOM 
                 2175 
                 CA 
                 LYS 
                 A 
                 274 
                 110.282 
                 31.923 
                 −20.253 
                 1.00 
                 141.98 
                 C 
               
               
                 ATOM 
                 2176 
                 CB 
                 LYS 
                 A 
                 274 
                 109.711 
                 30.519 
                 −20.480 
                 1.00 
                 144.49 
                 C 
               
               
                 ATOM 
                 2177 
                 CG 
                 LYS 
                 A 
                 274 
                 110.568 
                 29.656 
                 −21.397 
                 1.00 
                 147.46 
                 C 
               
               
                 ATOM 
                 2178 
                 CD 
                 LYS 
                 A 
                 274 
                 110.051 
                 28.230 
                 −21.495 
                 1.00 
                 149.98 
                 C 
               
               
                 ATOM 
                 2179 
                 CE 
                 LYS 
                 A 
                 274 
                 110.973 
                 27.373 
                 −22.348 
                 1.00 
                 151.33 
                 C 
               
               
                 ATOM 
                 2180 
                 NZ 
                 LYS 
                 A 
                 274 
                 110.500 
                 25.966 
                 −22.455 
                 1.00 
                 152.26 
                 N 
               
               
                 ATOM 
                 2181 
                 C 
                 LYS 
                 A 
                 274 
                 109.295 
                 32.783 
                 −19.456 
                 1.00 
                 143.02 
                 C 
               
               
                 ATOM 
                 2182 
                 O 
                 LYS 
                 A 
                 274 
                 108.337 
                 33.311 
                 −20.018 
                 1.00 
                 141.96 
                 O 
               
               
                 ATOM 
                 2183 
                 N 
                 LEU 
                 A 
                 275 
                 109.533 
                 32.916 
                 −18.152 
                 1.00 
                 149.30 
                 N 
               
               
                 ATOM 
                 2184 
                 CA 
                 LEU 
                 A 
                 275 
                 108.716 
                 33.777 
                 −17.291 
                 1.00 
                 154.74 
                 C 
               
               
                 ATOM 
                 2185 
                 CB 
                 LEU 
                 A 
                 275 
                 108.867 
                 33.374 
                 −15.819 
                 1.00 
                 158.31 
                 C 
               
               
                 ATOM 
                 2186 
                 CG 
                 LEU 
                 A 
                 275 
                 108.535 
                 31.925 
                 −15.445 
                 1.00 
                 162.45 
                 C 
               
               
                 ATOM 
                 2187 
                 CD1 
                 LEU 
                 A 
                 275 
                 108.845 
                 31.673 
                 −13.976 
                 1.00 
                 161.31 
                 C 
               
               
                 ATOM 
                 2188 
                 CD2 
                 LEU 
                 A 
                 275 
                 107.082 
                 31.590 
                 −15.755 
                 1.00 
                 162.69 
                 C 
               
               
                 ATOM 
                 2189 
                 C 
                 LEU 
                 A 
                 275 
                 109.105 
                 35.249 
                 −17.455 
                 1.00 
                 154.01 
                 C 
               
               
                 ATOM 
                 2190 
                 O 
                 LEU 
                 A 
                 275 
                 108.273 
                 36.138 
                 −17.273 
                 1.00 
                 153.38 
                 O 
               
               
                 ATOM 
                 2191 
                 N 
                 ILE 
                 A 
                 276 
                 110.371 
                 35.496 
                 −17.792 
                 1.00 
                 155.71 
                 N 
               
               
                 ATOM 
                 2192 
                 CA 
                 ILE 
                 A 
                 276 
                 110.884 
                 36.858 
                 −17.988 
                 1.00 
                 155.92 
                 C 
               
               
                 ATOM 
                 2193 
                 CB 
                 ILE 
                 A 
                 276 
                 112.436 
                 36.874 
                 −18.018 
                 1.00 
                 156.41 
                 C 
               
               
                 ATOM 
                 2194 
                 CG1 
                 ILE 
                 A 
                 276 
                 112.996 
                 36.460 
                 −16.651 
                 1.00 
                 155.75 
                 C 
               
               
                 ATOM 
                 2195 
                 CD1 
                 ILE 
                 A 
                 276 
                 114.482 
                 36.168 
                 −16.645 
                 1.00 
                 153.90 
                 C 
               
               
                 ATOM 
                 2196 
                 CG2 
                 ILE 
                 A 
                 276 
                 112.967 
                 38.256 
                 −18.385 
                 1.00 
                 155.85 
                 C 
               
               
                 ATOM 
                 2197 
                 C 
                 ILE 
                 A 
                 276 
                 110.315 
                 37.506 
                 −19.259 
                 1.00 
                 154.59 
                 C 
               
               
                 ATOM 
                 2198 
                 O 
                 ILE 
                 A 
                 276 
                 110.170 
                 38.728 
                 −19.320 
                 1.00 
                 152.55 
                 O 
               
               
                 ATOM 
                 2199 
                 N 
                 SER 
                 A 
                 277 
                 109.987 
                 36.690 
                 −20.261 
                 1.00 
                 154.98 
                 N 
               
               
                 ATOM 
                 2200 
                 CA 
                 SER 
                 A 
                 277 
                 109.430 
                 37.192 
                 −21.524 
                 1.00 
                 153.95 
                 C 
               
               
                 ATOM 
                 2201 
                 CB 
                 SER 
                 A 
                 277 
                 109.402 
                 36.082 
                 −22.582 
                 1.00 
                 150.69 
                 C 
               
               
                 ATOM 
                 2202 
                 OG 
                 SER 
                 A 
                 277 
                 108.569 
                 35.007 
                 −22.185 
                 1.00 
                 147.26 
                 O 
               
               
                 ATOM 
                 2203 
                 C 
                 SER 
                 A 
                 277 
                 108.027 
                 37.791 
                 −21.363 
                 1.00 
                 156.19 
                 C 
               
               
                 ATOM 
                 2204 
                 O 
                 SER 
                 A 
                 277 
                 107.674 
                 38.743 
                 −22.061 
                 1.00 
                 157.19 
                 O 
               
               
                 ATOM 
                 2205 
                 N 
                 GLU 
                 A 
                 278 
                 107.239 
                 37.231 
                 −20.446 
                 1.00 
                 156.49 
                 N 
               
               
                 ATOM 
                 2206 
                 CA 
                 GLU 
                 A 
                 278 
                 105.871 
                 37.700 
                 −20.194 
                 1.00 
                 152.92 
                 C 
               
               
                 ATOM 
                 2207 
                 CB 
                 GLU 
                 A 
                 278 
                 105.094 
                 36.667 
                 −19.369 
                 1.00 
                 151.29 
                 C 
               
               
                 ATOM 
                 2208 
                 CG 
                 GLU 
                 A 
                 278 
                 104.885 
                 35.335 
                 −20.078 
                 1.00 
                 150.66 
                 C 
               
               
                 ATOM 
                 2209 
                 CD 
                 GLU 
                 A 
                 278 
                 104.176 
                 34.299 
                 −19.219 
                 1.00 
                 149.23 
                 C 
               
               
                 ATOM 
                 2210 
                 OE1 
                 GLU 
                 A 
                 278 
                 104.099 
                 34.478 
                 −17.984 
                 1.00 
                 145.23 
                 O 
               
               
                 ATOM 
                 2211 
                 OE2 
                 GLU 
                 A 
                 278 
                 103.700 
                 33.292 
                 −19.784 
                 1.00 
                 148.65 
                 O 
               
               
                 ATOM 
                 2212 
                 C 
                 GLU 
                 A 
                 278 
                 105.854 
                 39.051 
                 −19.480 
                 1.00 
                 149.61 
                 C 
               
               
                 ATOM 
                 2213 
                 O 
                 GLU 
                 A 
                 278 
                 106.758 
                 39.374 
                 −18.709 
                 1.00 
                 145.55 
                 O 
               
               
                 HETATM 
                 2214 
                 C1 
                 NAG 
                 A 
                 300 
                 92.231 
                 29.653 
                 25.803 
                 1.00 
                 88.06 
                 C 
               
               
                 HETATM 
                 2215 
                 C2 
                 NAG 
                 A 
                 300 
                 93.546 
                 29.976 
                 26.521 
                 1.00 
                 88.70 
                 C 
               
               
                 HETATM 
                 2216 
                 N2 
                 NAG 
                 A 
                 300 
                 94.628 
                 30.106 
                 25.559 
                 1.00 
                 88.07 
                 N 
               
               
                 HETATM 
                 2217 
                 C7 
                 NAG 
                 A 
                 300 
                 94.728 
                 31.148 
                 24.730 
                 1.00 
                 88.36 
                 C 
               
               
                 HETATM 
                 2218 
                 O7 
                 NAG 
                 A 
                 300 
                 93.922 
                 32.075 
                 24.698 
                 1.00 
                 86.86 
                 O 
               
               
                 HETATM 
                 2219 
                 C8 
                 NAG 
                 A 
                 300 
                 95.899 
                 31.162 
                 23.792 
                 1.00 
                 89.47 
                 C 
               
               
                 HETATM 
                 2220 
                 C3 
                 NAG 
                 A 
                 300 
                 93.936 
                 28.982 
                 27.618 
                 1.00 
                 93.40 
                 C 
               
               
                 HETATM 
                 2221 
                 O3 
                 NAG 
                 A 
                 300 
                 94.906 
                 29.554 
                 28.468 
                 1.00 
                 91.90 
                 O 
               
               
                 HETATM 
                 2222 
                 C4 
                 NAG 
                 A 
                 300 
                 92.725 
                 28.576 
                 28.442 
                 1.00 
                 97.32 
                 C 
               
               
                 HETATM 
                 2223 
                 O4 
                 NAG 
                 A 
                 300 
                 93.069 
                 27.586 
                 29.395 
                 1.00 
                 107.70 
                 O 
               
               
                 HETATM 
                 2224 
                 C5 
                 NAG 
                 A 
                 300 
                 91.667 
                 28.059 
                 27.480 
                 1.00 
                 94.56 
                 C 
               
               
                 HETATM 
                 2225 
                 C6 
                 NAG 
                 A 
                 300 
                 90.444 
                 27.489 
                 28.189 
                 1.00 
                 95.47 
                 C 
               
               
                 HETATM 
                 2226 
                 O6 
                 NAG 
                 A 
                 300 
                 89.905 
                 28.462 
                 29.053 
                 1.00 
                 98.19 
                 O 
               
               
                 HETATM 
                 2227 
                 O5 
                 NAG 
                 A 
                 300 
                 91.261 
                 29.151 
                 26.700 
                 1.00 
                 88.89 
                 O 
               
               
                 HETATM 
                 2228 
                 C1 
                 NAG 
                 A 
                 301 
                 93.078 
                 28.120 
                 30.733 
                 1.00 
                 119.47 
                 C 
               
               
                 HETATM 
                 2229 
                 C2 
                 NAG 
                 A 
                 301 
                 92.849 
                 26.984 
                 31.739 
                 1.00 
                 125.81 
                 C 
               
               
                 HETATM 
                 2230 
                 N2 
                 NAG 
                 A 
                 301 
                 91.499 
                 26.413 
                 31.646 
                 1.00 
                 126.51 
                 N 
               
               
                 HETATM 
                 2231 
                 C7 
                 NAG 
                 A 
                 301 
                 90.352 
                 27.055 
                 31.942 
                 1.00 
                 121.91 
                 C 
               
               
                 HETATM 
                 2232 
                 O7 
                 NAG 
                 A 
                 301 
                 90.283 
                 28.222 
                 32.329 
                 1.00 
                 120.28 
                 O 
               
               
                 HETATM 
                 2233 
                 C8 
                 NAG 
                 A 
                 301 
                 89.070 
                 26.285 
                 31.782 
                 1.00 
                 117.84 
                 C 
               
               
                 HETATM 
                 2234 
                 C3 
                 NAG 
                 A 
                 301 
                 93.193 
                 27.361 
                 33.192 
                 1.00 
                 131.36 
                 C 
               
               
                 HETATM 
                 2235 
                 O3 
                 NAG 
                 A 
                 301 
                 93.482 
                 26.189 
                 33.923 
                 1.00 
                 130.30 
                 O 
               
               
                 HETATM 
                 2236 
                 C4 
                 NAG 
                 A 
                 301 
                 94.367 
                 28.330 
                 33.322 
                 1.00 
                 133.81 
                 C 
               
               
                 HETATM 
                 2237 
                 O4 
                 NAG 
                 A 
                 301 
                 94.322 
                 28.954 
                 34.594 
                 1.00 
                 141.80 
                 O 
               
               
                 HETATM 
                 2238 
                 C5 
                 NAG 
                 A 
                 301 
                 94.319 
                 29.408 
                 32.244 
                 1.00 
                 130.44 
                 C 
               
               
                 HETATM 
                 2239 
                 C6 
                 NAG 
                 A 
                 301 
                 95.511 
                 30.359 
                 32.319 
                 1.00 
                 130.22 
                 C 
               
               
                 HETATM 
                 2240 
                 O6 
                 NAG 
                 A 
                 301 
                 96.715 
                 29.646 
                 32.140 
                 1.00 
                 133.23 
                 O 
               
               
                 HETATM 
                 2241 
                 O5 
                 NAG 
                 A 
                 301 
                 94.303 
                 28.769 
                 30.987 
                 1.00 
                 122.75 
                 O 
               
               
                 HETATM 
                 2242 
                 C1 
                 BMA 
                 A 
                 302 
                 95.375 
                 28.514 
                 35.477 
                 1.00 
                 149.86 
                 C 
               
               
                 HETATM 
                 2243 
                 O5 
                 BMA 
                 A 
                 302 
                 94.924 
                 27.535 
                 36.414 
                 1.00 
                 151.87 
                 O 
               
               
                 HETATM 
                 2244 
                 C5 
                 BMA 
                 A 
                 302 
                 95.978 
                 27.001 
                 37.222 
                 1.00 
                 152.13 
                 C 
               
               
                 HETATM 
                 2245 
                 C6 
                 BMA 
                 A 
                 302 
                 95.407 
                 25.922 
                 38.135 
                 1.00 
                 149.41 
                 C 
               
               
                 HETATM 
                 2246 
                 O6 
                 BMA 
                 A 
                 302 
                 96.469 
                 25.123 
                 38.669 
                 1.00 
                 146.07 
                 O 
               
               
                 HETATM 
                 2247 
                 C4 
                 BMA 
                 A 
                 302 
                 96.644 
                 28.114 
                 38.030 
                 1.00 
                 154.34 
                 C 
               
               
                 HETATM 
                 2248 
                 O4 
                 BMA 
                 A 
                 302 
                 97.780 
                 27.590 
                 38.726 
                 1.00 
                 158.54 
                 O 
               
               
                 HETATM 
                 2249 
                 C3 
                 BMA 
                 A 
                 302 
                 97.086 
                 29.262 
                 37.127 
                 1.00 
                 152.99 
                 C 
               
               
                 HETATM 
                 2250 
                 O3 
                 BMA 
                 A 
                 302 
                 97.557 
                 30.359 
                 37.919 
                 1.00 
                 152.44 
                 O 
               
               
                 HETATM 
                 2251 
                 C2 
                 BMA 
                 A 
                 302 
                 95.929 
                 29.708 
                 36.241 
                 1.00 
                 151.92 
                 C 
               
               
                 HETATM 
                 2252 
                 O2 
                 BMA 
                 A 
                 302 
                 94.893 
                 30.288 
                 37.041 
                 1.00 
                 152.03 
                 O 
               
               
                 HETATM 
                 2253 
                 C1 
                 NAG 
                 A 
                 310 
                 94.583 
                 20.869 
                 27.777 
                 1.00 
                 109.65 
                 C 
               
               
                 HETATM 
                 2254 
                 C2 
                 NAG 
                 A 
                 310 
                 95.465 
                 21.038 
                 29.004 
                 1.00 
                 117.28 
                 C 
               
               
                 HETATM 
                 2255 
                 N2 
                 NAG 
                 A 
                 310 
                 94.903 
                 22.024 
                 29.913 
                 1.00 
                 119.62 
                 N 
               
               
                 HETATM 
                 2256 
                 C7 
                 NAG 
                 A 
                 310 
                 94.647 
                 21.772 
                 31.201 
                 1.00 
                 120.08 
                 C 
               
               
                 HETATM 
                 2257 
                 O7 
                 NAG 
                 A 
                 310 
                 94.862 
                 20.689 
                 31.749 
                 1.00 
                 116.82 
                 O 
               
               
                 HETATM 
                 2258 
                 C8 
                 NAG 
                 A 
                 310 
                 94.062 
                 22.903 
                 31.995 
                 1.00 
                 120.22 
                 C 
               
               
                 HETATM 
                 2259 
                 C3 
                 NAG 
                 A 
                 310 
                 96.852 
                 21.445 
                 28.534 
                 1.00 
                 119.67 
                 C 
               
               
                 HETATM 
                 2260 
                 O3 
                 NAG 
                 A 
                 310 
                 97.726 
                 21.550 
                 29.634 
                 1.00 
                 119.10 
                 O 
               
               
                 HETATM 
                 2261 
                 C4 
                 NAG 
                 A 
                 310 
                 97.370 
                 20.405 
                 27.550 
                 1.00 
                 122.93 
                 C 
               
               
                 HETATM 
                 2262 
                 O4 
                 NAG 
                 A 
                 310 
                 98.524 
                 20.918 
                 26.929 
                 1.00 
                 135.19 
                 O 
               
               
                 HETATM 
                 2263 
                 C5 
                 NAG 
                 A 
                 310 
                 96.349 
                 20.102 
                 26.453 
                 1.00 
                 118.12 
                 C 
               
               
                 HETATM 
                 2264 
                 C6 
                 NAG 
                 A 
                 310 
                 96.764 
                 18.929 
                 25.573 
                 1.00 
                 118.70 
                 C 
               
               
                 HETATM 
                 2265 
                 O6 
                 NAG 
                 A 
                 310 
                 96.949 
                 17.778 
                 26.368 
                 1.00 
                 116.86 
                 O 
               
               
                 HETATM 
                 2266 
                 O5 
                 NAG 
                 A 
                 310 
                 95.092 
                 19.805 
                 27.013 
                 1.00 
                 111.69 
                 O 
               
               
                 HETATM 
                 2267 
                 C1 
                 NAG 
                 A 
                 311 
                 99.746 
                 20.381 
                 27.460 
                 1.00 
                 146.81 
                 C 
               
               
                 HETATM 
                 2268 
                 C2 
                 NAG 
                 A 
                 311 
                 100.639 
                 20.109 
                 26.250 
                 1.00 
                 148.11 
                 C 
               
               
                 HETATM 
                 2269 
                 N2 
                 NAG 
                 A 
                 311 
                 100.161 
                 18.923 
                 25.555 
                 1.00 
                 144.86 
                 N 
               
               
                 HETATM 
                 2270 
                 C7 
                 NAG 
                 A 
                 311 
                 100.351 
                 18.733 
                 24.248 
                 1.00 
                 143.26 
                 C 
               
               
                 HETATM 
                 2271 
                 O7 
                 NAG 
                 A 
                 311 
                 100.947 
                 19.539 
                 23.536 
                 1.00 
                 143.90 
                 O 
               
               
                 HETATM 
                 2272 
                 C8 
                 NAG 
                 A 
                 311 
                 99.804 
                 17.470 
                 23.646 
                 1.00 
                 142.28 
                 C 
               
               
                 HETATM 
                 2273 
                 C3 
                 NAG 
                 A 
                 311 
                 102.113 
                 19.945 
                 26.600 
                 1.00 
                 155.81 
                 C 
               
               
                 HETATM 
                 2274 
                 O3 
                 NAG 
                 A 
                 311 
                 102.863 
                 20.077 
                 25.415 
                 1.00 
                 155.79 
                 O 
               
               
                 HETATM 
                 2275 
                 C4 
                 NAG 
                 A 
                 311 
                 102.529 
                 20.992 
                 27.627 
                 1.00 
                 163.01 
                 C 
               
               
                 HETATM 
                 2276 
                 O4 
                 NAG 
                 A 
                 311 
                 103.872 
                 20.824 
                 28.030 
                 1.00 
                 170.20 
                 O 
               
               
                 HETATM 
                 2277 
                 C5 
                 NAG 
                 A 
                 311 
                 101.598 
                 20.888 
                 28.828 
                 1.00 
                 162.22 
                 C 
               
               
                 HETATM 
                 2278 
                 C6 
                 NAG 
                 A 
                 311 
                 102.043 
                 21.767 
                 29.996 
                 1.00 
                 160.93 
                 C 
               
               
                 HETATM 
                 2279 
                 O6 
                 NAG 
                 A 
                 311 
                 101.095 
                 21.690 
                 31.037 
                 1.00 
                 156.34 
                 O 
               
               
                 HETATM 
                 2280 
                 O5 
                 NAG 
                 A 
                 311 
                 100.320 
                 21.283 
                 28.383 
                 1.00 
                 155.90 
                 O 
               
               
                 HETATM 
                 2281 
                 C1 
                 BMA 
                 A 
                 312 
                 104.801 
                 21.457 
                 27.128 
                 1.00 
                 173.77 
                 C 
               
               
                 HETATM 
                 2282 
                 O5 
                 BMA 
                 A 
                 312 
                 105.738 
                 20.504 
                 26.637 
                 1.00 
                 175.56 
                 O 
               
               
                 HETATM 
                 2283 
                 C5 
                 BMA 
                 A 
                 312 
                 106.642 
                 21.022 
                 25.661 
                 1.00 
                 174.38 
                 C 
               
               
                 HETATM 
                 2284 
                 C6 
                 BMA 
                 A 
                 312 
                 107.457 
                 19.854 
                 25.107 
                 1.00 
                 173.09 
                 C 
               
               
                 HETATM 
                 2285 
                 O6 
                 BMA 
                 A 
                 312 
                 106.897 
                 19.386 
                 23.867 
                 1.00 
                 173.14 
                 O 
               
               
                 HETATM 
                 2286 
                 C4 
                 BMA 
                 A 
                 312 
                 107.488 
                 22.118 
                 26.308 
                 1.00 
                 174.90 
                 C 
               
               
                 HETATM 
                 2287 
                 O4 
                 BMA 
                 A 
                 312 
                 108.372 
                 22.697 
                 25.341 
                 1.00 
                 170.26 
                 O 
               
               
                 HETATM 
                 2288 
                 C3 
                 BMA 
                 A 
                 312 
                 106.560 
                 23.196 
                 26.872 
                 1.00 
                 176.32 
                 C 
               
               
                 HETATM 
                 2289 
                 O3 
                 BMA 
                 A 
                 312 
                 107.308 
                 24.319 
                 27.392 
                 1.00 
                 179.24 
                 O 
               
               
                 HETATM 
                 2290 
                 C2 
                 BMA 
                 A 
                 312 
                 105.549 
                 22.571 
                 27.845 
                 1.00 
                 175.80 
                 C 
               
               
                 HETATM 
                 2291 
                 O2 
                 BMA 
                 A 
                 312 
                 106.163 
                 21.983 
                 28.997 
                 1.00 
                 179.19 
                 O 
               
               
                 HETATM 
                 2292 
                 C1 
                 MAN 
                 A 
                 313 
                 105.668 
                 18.645 
                 24.052 
                 1.00 
                 173.82 
                 C 
               
               
                 HETATM 
                 2293 
                 C2 
                 MAN 
                 A 
                 313 
                 105.951 
                 17.157 
                 24.240 
                 1.00 
                 173.85 
                 C 
               
               
                 HETATM 
                 2294 
                 O2 
                 MAN 
                 A 
                 313 
                 104.749 
                 16.562 
                 24.671 
                 1.00 
                 170.58 
                 O 
               
               
                 HETATM 
                 2295 
                 C3 
                 MAN 
                 A 
                 313 
                 106.456 
                 16.548 
                 22.927 
                 1.00 
                 175.11 
                 C 
               
               
                 HETATM 
                 2296 
                 O3 
                 MAN 
                 A 
                 313 
                 106.892 
                 15.191 
                 23.021 
                 1.00 
                 179.56 
                 O 
               
               
                 HETATM 
                 2297 
                 C4 
                 MAN 
                 A 
                 313 
                 105.468 
                 16.852 
                 21.794 
                 1.00 
                 173.27 
                 C 
               
               
                 HETATM 
                 2298 
                 O4 
                 MAN 
                 A 
                 313 
                 106.007 
                 16.404 
                 20.573 
                 1.00 
                 171.08 
                 O 
               
               
                 HETATM 
                 2299 
                 C5 
                 MAN 
                 A 
                 313 
                 105.196 
                 18.355 
                 21.719 
                 1.00 
                 173.04 
                 C 
               
               
                 HETATM 
                 2300 
                 C6 
                 MAN 
                 A 
                 313 
                 104.164 
                 18.707 
                 20.645 
                 1.00 
                 169.96 
                 C 
               
               
                 HETATM 
                 2301 
                 O6 
                 MAN 
                 A 
                 313 
                 102.944 
                 18.034 
                 20.866 
                 1.00 
                 163.68 
                 O 
               
               
                 HETATM 
                 2302 
                 O5 
                 MAN 
                 A 
                 313 
                 104.756 
                 18.830 
                 22.980 
                 1.00 
                 175.64 
                 O 
               
               
                 HETATM 
                 2303 
                 C1 
                 MAN 
                 A 
                 314 
                 105.922 
                 14.184 
                 23.394 
                 1.00 
                 178.69 
                 C 
               
               
                 HETATM 
                 2304 
                 C2 
                 MAN 
                 A 
                 314 
                 106.171 
                 13.732 
                 24.832 
                 1.00 
                 175.17 
                 C 
               
               
                 HETATM 
                 2305 
                 O2 
                 MAN 
                 A 
                 314 
                 105.094 
                 12.927 
                 25.259 
                 1.00 
                 167.65 
                 O 
               
               
                 HETATM 
                 2306 
                 C3 
                 MAN 
                 A 
                 314 
                 107.477 
                 12.949 
                 24.950 
                 1.00 
                 175.89 
                 C 
               
               
                 HETATM 
                 2307 
                 O3 
                 MAN 
                 A 
                 314 
                 107.610 
                 12.413 
                 26.248 
                 1.00 
                 175.01 
                 O 
               
               
                 HETATM 
                 2308 
                 C4 
                 MAN 
                 A 
                 314 
                 107.523 
                 11.824 
                 23.924 
                 1.00 
                 177.70 
                 C 
               
               
                 HETATM 
                 2309 
                 O4 
                 MAN 
                 A 
                 314 
                 108.804 
                 11.232 
                 23.946 
                 1.00 
                 175.31 
                 O 
               
               
                 HETATM 
                 2310 
                 C5 
                 MAN 
                 A 
                 314 
                 107.221 
                 12.378 
                 22.532 
                 1.00 
                 179.10 
                 C 
               
               
                 HETATM 
                 2311 
                 C6 
                 MAN 
                 A 
                 314 
                 107.184 
                 11.279 
                 21.474 
                 1.00 
                 177.74 
                 C 
               
               
                 HETATM 
                 2312 
                 O6 
                 MAN 
                 A 
                 314 
                 106.145 
                 10.367 
                 21.754 
                 1.00 
                 177.31 
                 O 
               
               
                 HETATM 
                 2313 
                 O5 
                 MAN 
                 A 
                 314 
                 105.974 
                 13.053 
                 22.545 
                 1.00 
                 180.90 
                 O 
               
               
                 HETATM 
                 2314 
                 C1 
                 MAN 
                 A 
                 315 
                 107.996 
                 24.177 
                 28.656 
                 1.00 
                 178.04 
                 C 
               
               
                 HETATM 
                 2315 
                 C2 
                 MAN 
                 A 
                 315 
                 107.861 
                 25.503 
                 29.400 
                 1.00 
                 176.71 
                 C 
               
               
                 HETATM 
                 2316 
                 O2 
                 MAN 
                 A 
                 315 
                 108.273 
                 25.337 
                 30.738 
                 1.00 
                 176.35 
                 O 
               
               
                 HETATM 
                 2317 
                 C3 
                 MAN 
                 A 
                 315 
                 108.691 
                 26.587 
                 28.720 
                 1.00 
                 174.62 
                 C 
               
               
                 HETATM 
                 2318 
                 O3 
                 MAN 
                 A 
                 315 
                 108.650 
                 27.779 
                 29.472 
                 1.00 
                 174.02 
                 O 
               
               
                 HETATM 
                 2319 
                 C4 
                 MAN 
                 A 
                 315 
                 110.134 
                 26.123 
                 28.555 
                 1.00 
                 174.24 
                 C 
               
               
                 HETATM 
                 2320 
                 O4 
                 MAN 
                 A 
                 315 
                 110.840 
                 27.087 
                 27.806 
                 1.00 
                 169.00 
                 O 
               
               
                 HETATM 
                 2321 
                 C5 
                 MAN 
                 A 
                 315 
                 110.186 
                 24.763 
                 27.856 
                 1.00 
                 175.46 
                 C 
               
               
                 HETATM 
                 2322 
                 C6 
                 MAN 
                 A 
                 315 
                 111.599 
                 24.182 
                 27.804 
                 1.00 
                 172.54 
                 C 
               
               
                 HETATM 
                 2323 
                 O6 
                 MAN 
                 A 
                 315 
                 112.577 
                 25.196 
                 27.752 
                 1.00 
                 170.89 
                 O 
               
               
                 HETATM 
                 2324 
                 O5 
                 MAN 
                 A 
                 315 
                 109.361 
                 23.825 
                 28.526 
                 1.00 
                 178.20 
                 O 
               
               
                 HETATM 
                 2325 
                 C1 
                 NAG 
                 A 
                 320 
                 99.704 
                 11.932 
                 5.032 
                 1.00 
                 78.00 
                 C 
               
               
                 HETATM 
                 2326 
                 C2 
                 NAG 
                 A 
                 320 
                 101.063 
                 11.242 
                 5.063 
                 1.00 
                 79.63 
                 C 
               
               
                 HETATM 
                 2327 
                 N2 
                 NAG 
                 A 
                 320 
                 101.690 
                 11.279 
                 3.754 
                 1.00 
                 81.27 
                 N 
               
               
                 HETATM 
                 2328 
                 C7 
                 NAG 
                 A 
                 320 
                 102.732 
                 12.057 
                 3.458 
                 1.00 
                 83.86 
                 C 
               
               
                 HETATM 
                 2329 
                 O7 
                 NAG 
                 A 
                 320 
                 103.272 
                 12.831 
                 4.251 
                 1.00 
                 85.89 
                 O 
               
               
                 HETATM 
                 2330 
                 C8 
                 NAG 
                 A 
                 320 
                 103.254 
                 11.957 
                 2.055 
                 1.00 
                 84.99 
                 C 
               
               
                 HETATM 
                 2331 
                 C3 
                 NAG 
                 A 
                 320 
                 100.933 
                 9.788 
                 5.507 
                 1.00 
                 79.53 
                 C 
               
               
                 HETATM 
                 2332 
                 O3 
                 NAG 
                 A 
                 320 
                 102.213 
                 9.258 
                 5.761 
                 1.00 
                 78.00 
                 O 
               
               
                 HETATM 
                 2333 
                 C4 
                 NAG 
                 A 
                 320 
                 100.100 
                 9.685 
                 6.772 
                 1.00 
                 80.67 
                 C 
               
               
                 HETATM 
                 2334 
                 O4 
                 NAG 
                 A 
                 320 
                 99.818 
                 8.327 
                 7.056 
                 1.00 
                 85.62 
                 O 
               
               
                 HETATM 
                 2335 
                 C5 
                 NAG 
                 A 
                 320 
                 98.796 
                 10.457 
                 6.615 
                 1.00 
                 78.92 
                 C 
               
               
                 HETATM 
                 2336 
                 C6 
                 NAG 
                 A 
                 320 
                 97.984 
                 10.436 
                 7.902 
                 1.00 
                 81.04 
                 C 
               
               
                 HETATM 
                 2337 
                 O6 
                 NAG 
                 A 
                 320 
                 98.777 
                 10.903 
                 8.973 
                 1.00 
                 82.77 
                 O 
               
               
                 HETATM 
                 2338 
                 O5 
                 NAG 
                 A 
                 320 
                 99.095 
                 11.795 
                 6.297 
                 1.00 
                 77.52 
                 O 
               
               
                 HETATM 
                 2339 
                 C1 
                 NAG 
                 A 
                 321 
                 100.443 
                 7.908 
                 8.284 
                 1.00 
                 90.18 
                 C 
               
               
                 HETATM 
                 2340 
                 C2 
                 NAG 
                 A 
                 321 
                 99.708 
                 6.704 
                 8.850 
                 1.00 
                 90.56 
                 C 
               
               
                 HETATM 
                 2341 
                 N2 
                 NAG 
                 A 
                 321 
                 98.319 
                 7.015 
                 9.118 
                 1.00 
                 86.90 
                 N 
               
               
                 HETATM 
                 2342 
                 C7 
                 NAG 
                 A 
                 321 
                 97.320 
                 6.575 
                 8.360 
                 1.00 
                 86.04 
                 C 
               
               
                 HETATM 
                 2343 
                 O7 
                 NAG 
                 A 
                 321 
                 97.469 
                 5.880 
                 7.356 
                 1.00 
                 86.02 
                 O 
               
               
                 HETATM 
                 2344 
                 C8 
                 NAG 
                 A 
                 321 
                 95.949 
                 6.988 
                 8.795 
                 1.00 
                 86.14 
                 C 
               
               
                 HETATM 
                 2345 
                 C3 
                 NAG 
                 A 
                 321 
                 100.336 
                 6.267 
                 10.162 
                 1.00 
                 95.00 
                 C 
               
               
                 HETATM 
                 2346 
                 O3 
                 NAG 
                 A 
                 321 
                 99.774 
                 5.031 
                 10.540 
                 1.00 
                 94.11 
                 O 
               
               
                 HETATM 
                 2347 
                 C4 
                 NAG 
                 A 
                 321 
                 101.852 
                 6.146 
                 10.078 
                 1.00 
                 99.90 
                 C 
               
               
                 HETATM 
                 2348 
                 O4 
                 NAG 
                 A 
                 321 
                 102.343 
                 6.206 
                 11.401 
                 1.00 
                 111.46 
                 O 
               
               
                 HETATM 
                 2349 
                 C5 
                 NAG 
                 A 
                 321 
                 102.493 
                 7.282 
                 9.281 
                 1.00 
                 97.44 
                 C 
               
               
                 HETATM 
                 2350 
                 C6 
                 NAG 
                 A 
                 321 
                 103.947 
                 6.969 
                 8.938 
                 1.00 
                 97.10 
                 C 
               
               
                 HETATM 
                 2351 
                 O6 
                 NAG 
                 A 
                 321 
                 103.999 
                 6.031 
                 7.886 
                 1.00 
                 97.63 
                 O 
               
               
                 HETATM 
                 2352 
                 O5 
                 NAG 
                 A 
                 321 
                 101.790 
                 7.546 
                 8.083 
                 1.00 
                 94.30 
                 O 
               
               
                 HETATM 
                 2353 
                 C1 
                 BMA 
                 A 
                 322 
                 102.661 
                 4.906 
                 11.925 
                 1.00 
                 122.99 
                 C 
               
               
                 HETATM 
                 2354 
                 O5 
                 BMA 
                 A 
                 322 
                 101.525 
                 4.109 
                 12.255 
                 1.00 
                 127.83 
                 O 
               
               
                 HETATM 
                 2355 
                 C5 
                 BMA 
                 A 
                 322 
                 101.884 
                 2.771 
                 12.618 
                 1.00 
                 133.51 
                 C 
               
               
                 HETATM 
                 2356 
                 C6 
                 BMA 
                 A 
                 322 
                 100.615 
                 1.981 
                 12.924 
                 1.00 
                 137.04 
                 C 
               
               
                 HETATM 
                 2357 
                 O6 
                 BMA 
                 A 
                 322 
                 99.842 
                 2.620 
                 13.953 
                 1.00 
                 142.80 
                 O 
               
               
                 HETATM 
                 2358 
                 C4 
                 BMA 
                 A 
                 322 
                 102.860 
                 2.751 
                 13.801 
                 1.00 
                 134.12 
                 C 
               
               
                 HETATM 
                 2359 
                 O4 
                 BMA 
                 A 
                 322 
                 103.375 
                 1.426 
                 13.966 
                 1.00 
                 134.46 
                 O 
               
               
                 HETATM 
                 2360 
                 C3 
                 BMA 
                 A 
                 322 
                 104.027 
                 3.719 
                 13.595 
                 1.00 
                 134.38 
                 C 
               
               
                 HETATM 
                 2361 
                 O3 
                 BMA 
                 A 
                 322 
                 104.824 
                 3.820 
                 14.788 
                 1.00 
                 140.14 
                 O 
               
               
                 HETATM 
                 2362 
                 C2 
                 BMA 
                 A 
                 322 
                 103.480 
                 5.082 
                 13.190 
                 1.00 
                 128.00 
                 C 
               
               
                 HETATM 
                 2363 
                 O2 
                 BMA 
                 A 
                 322 
                 102.656 
                 5.617 
                 14.234 
                 1.00 
                 123.99 
                 O 
               
               
                 HETATM 
                 2364 
                 C1 
                 MAN 
                 A 
                 323 
                 106.165 
                 4.289 
                 14.504 
                 1.00 
                 144.86 
                 C 
               
               
                 HETATM 
                 2365 
                 C2 
                 MAN 
                 A 
                 323 
                 107.113 
                 3.102 
                 14.303 
                 1.00 
                 145.83 
                 C 
               
               
                 HETATM 
                 2366 
                 O2 
                 MAN 
                 A 
                 323 
                 108.221 
                 3.519 
                 13.532 
                 1.00 
                 142.79 
                 O 
               
               
                 HETATM 
                 2367 
                 C3 
                 MAN 
                 A 
                 323 
                 107.599 
                 2.476 
                 15.614 
                 1.00 
                 148.36 
                 C 
               
               
                 HETATM 
                 2368 
                 O3 
                 MAN 
                 A 
                 323 
                 108.743 
                 1.684 
                 15.376 
                 1.00 
                 147.23 
                 O 
               
               
                 HETATM 
                 2369 
                 C4 
                 MAN 
                 A 
                 323 
                 107.926 
                 3.522 
                 16.674 
                 1.00 
                 148.74 
                 C 
               
               
                 HETATM 
                 2370 
                 O4 
                 MAN 
                 A 
                 323 
                 108.112 
                 2.888 
                 17.920 
                 1.00 
                 149.10 
                 O 
               
               
                 HETATM 
                 2371 
                 C5 
                 MAN 
                 A 
                 323 
                 106.804 
                 4.549 
                 16.777 
                 1.00 
                 147.56 
                 C 
               
               
                 HETATM 
                 2372 
                 C6 
                 MAN 
                 A 
                 323 
                 107.115 
                 5.600 
                 17.840 
                 1.00 
                 145.14 
                 C 
               
               
                 HETATM 
                 2373 
                 O6 
                 MAN 
                 A 
                 323 
                 106.520 
                 6.836 
                 17.507 
                 1.00 
                 142.88 
                 O 
               
               
                 HETATM 
                 2374 
                 O5 
                 MAN 
                 A 
                 323 
                 106.646 
                 5.160 
                 15.511 
                 1.00 
                 147.26 
                 O 
               
               
                 HETATM 
                 2375 
                 C1 
                 MAN 
                 A 
                 324 
                 98.715 
                 1.788 
                 14.313 
                 1.00 
                 148.42 
                 C 
               
               
                 HETATM 
                 2376 
                 C2 
                 MAN 
                 A 
                 324 
                 97.413 
                 2.512 
                 13.959 
                 1.00 
                 148.60 
                 C 
               
               
                 HETATM 
                 2377 
                 O2 
                 MAN 
                 A 
                 324 
                 96.396 
                 1.554 
                 13.757 
                 1.00 
                 150.22 
                 O 
               
               
                 HETATM 
                 2378 
                 C3 
                 MAN 
                 A 
                 324 
                 96.973 
                 3.530 
                 15.015 
                 1.00 
                 149.37 
                 C 
               
               
                 HETATM 
                 2379 
                 O3 
                 MAN 
                 A 
                 324 
                 95.624 
                 3.891 
                 14.809 
                 1.00 
                 147.64 
                 O 
               
               
                 HETATM 
                 2380 
                 C4 
                 MAN 
                 A 
                 324 
                 97.141 
                 2.995 
                 16.432 
                 1.00 
                 149.92 
                 C 
               
               
                 HETATM 
                 2381 
                 O4 
                 MAN 
                 A 
                 324 
                 96.913 
                 4.039 
                 17.352 
                 1.00 
                 148.37 
                 O 
               
               
                 HETATM 
                 2382 
                 C5 
                 MAN 
                 A 
                 324 
                 98.542 
                 2.423 
                 16.616 
                 1.00 
                 150.46 
                 C 
               
               
                 HETATM 
                 2383 
                 C6 
                 MAN 
                 A 
                 324 
                 98.735 
                 1.846 
                 18.015 
                 1.00 
                 148.18 
                 C 
               
               
                 HETATM 
                 2384 
                 O6 
                 MAN 
                 A 
                 324 
                 98.707 
                 2.883 
                 18.969 
                 1.00 
                 148.30 
                 O 
               
               
                 HETATM 
                 2385 
                 O5 
                 MAN 
                 A 
                 324 
                 98.741 
                 1.389 
                 15.673 
                 1.00 
                 152.09 
                 O 
               
               
                 HETATM 
                 2386 
                 C1 
                 NAG 
                 A 
                 330 
                 113.415 
                 26.632 
                 18.299 
                 1.00 
                 110.44 
                 C 
               
               
                 HETATM 
                 2387 
                 C2 
                 NAG 
                 A 
                 330 
                 113.451 
                 27.224 
                 19.699 
                 1.00 
                 114.33 
                 C 
               
               
                 HETATM 
                 2388 
                 N2 
                 NAG 
                 A 
                 330 
                 112.698 
                 28.467 
                 19.720 
                 1.00 
                 110.83 
                 N 
               
               
                 HETATM 
                 2389 
                 C7 
                 NAG 
                 A 
                 330 
                 111.815 
                 28.817 
                 20.662 
                 1.00 
                 109.92 
                 C 
               
               
                 HETATM 
                 2390 
                 O7 
                 NAG 
                 A 
                 330 
                 111.216 
                 29.888 
                 20.603 
                 1.00 
                 108.90 
                 O 
               
               
                 HETATM 
                 2391 
                 C8 
                 NAG 
                 A 
                 330 
                 111.543 
                 27.895 
                 21.819 
                 1.00 
                 109.21 
                 C 
               
               
                 HETATM 
                 2392 
                 C3 
                 NAG 
                 A 
                 330 
                 114.898 
                 27.468 
                 20.090 
                 1.00 
                 118.83 
                 C 
               
               
                 HETATM 
                 2393 
                 O3 
                 NAG 
                 A 
                 330 
                 114.967 
                 27.874 
                 21.436 
                 1.00 
                 118.84 
                 O 
               
               
                 HETATM 
                 2394 
                 C4 
                 NAG 
                 A 
                 330 
                 115.703 
                 26.186 
                 19.892 
                 1.00 
                 123.15 
                 C 
               
               
                 HETATM 
                 2395 
                 O4 
                 NAG 
                 A 
                 330 
                 117.068 
                 26.467 
                 20.115 
                 1.00 
                 134.68 
                 O 
               
               
                 HETATM 
                 2396 
                 C5 
                 NAG 
                 A 
                 330 
                 115.502 
                 25.610 
                 18.490 
                 1.00 
                 117.64 
                 C 
               
               
                 HETATM 
                 2397 
                 C6 
                 NAG 
                 A 
                 330 
                 116.192 
                 24.267 
                 18.296 
                 1.00 
                 115.10 
                 C 
               
               
                 HETATM 
                 2398 
                 O6 
                 NAG 
                 A 
                 330 
                 115.595 
                 23.304 
                 19.137 
                 1.00 
                 110.28 
                 O 
               
               
                 HETATM 
                 2399 
                 O5 
                 NAG 
                 A 
                 330 
                 114.125 
                 25.419 
                 18.271 
                 1.00 
                 113.09 
                 O 
               
               
                 HETATM 
                 2400 
                 C1 
                 NAG 
                 A 
                 331 
                 117.623 
                 25.577 
                 21.098 
                 1.00 
                 141.38 
                 C 
               
               
                 HETATM 
                 2401 
                 C2 
                 NAG 
                 A 
                 331 
                 119.097 
                 25.938 
                 21.284 
                 1.00 
                 142.10 
                 C 
               
               
                 HETATM 
                 2402 
                 N2 
                 NAG 
                 A 
                 331 
                 119.820 
                 25.923 
                 20.014 
                 1.00 
                 137.18 
                 N 
               
               
                 HETATM 
                 2403 
                 C7 
                 NAG 
                 A 
                 331 
                 120.034 
                 24.827 
                 19.278 
                 1.00 
                 132.94 
                 C 
               
               
                 HETATM 
                 2404 
                 O7 
                 NAG 
                 A 
                 331 
                 119.651 
                 23.703 
                 19.593 
                 1.00 
                 130.56 
                 O 
               
               
                 HETATM 
                 2405 
                 C8 
                 NAG 
                 A 
                 331 
                 120.795 
                 25.006 
                 17.995 
                 1.00 
                 132.22 
                 C 
               
               
                 HETATM 
                 2406 
                 C3 
                 NAG 
                 A 
                 331 
                 119.740 
                 25.076 
                 22.372 
                 1.00 
                 146.26 
                 C 
               
               
                 HETATM 
                 2407 
                 O3 
                 NAG 
                 A 
                 331 
                 121.036 
                 25.546 
                 22.661 
                 1.00 
                 145.00 
                 O 
               
               
                 HETATM 
                 2408 
                 C4 
                 NAG 
                 A 
                 331 
                 118.870 
                 25.127 
                 23.623 
                 1.00 
                 152.12 
                 C 
               
               
                 HETATM 
                 2409 
                 O4 
                 NAG 
                 A 
                 331 
                 119.398 
                 24.297 
                 24.638 
                 1.00 
                 162.28 
                 O 
               
               
                 HETATM 
                 2410 
                 C5 
                 NAG 
                 A 
                 331 
                 117.443 
                 24.712 
                 23.273 
                 1.00 
                 149.81 
                 C 
               
               
                 HETATM 
                 2411 
                 C6 
                 NAG 
                 A 
                 331 
                 116.516 
                 24.666 
                 24.486 
                 1.00 
                 149.59 
                 C 
               
               
                 HETATM 
                 2412 
                 O6 
                 NAG 
                 A 
                 331 
                 116.467 
                 25.929 
                 25.110 
                 1.00 
                 150.33 
                 O 
               
               
                 HETATM 
                 2413 
                 O5 
                 NAG 
                 A 
                 331 
                 116.951 
                 25.649 
                 22.340 
                 1.00 
                 144.92 
                 O 
               
               
                 HETATM 
                 2414 
                 C1 
                 BMA 
                 A 
                 332 
                 119.957 
                 25.093 
                 25.701 
                 1.00 
                 168.28 
                 C 
               
               
                 HETATM 
                 2415 
                 O5 
                 BMA 
                 A 
                 332 
                 121.230 
                 25.636 
                 25.363 
                 1.00 
                 170.32 
                 O 
               
               
                 HETATM 
                 2416 
                 C5 
                 BMA 
                 A 
                 332 
                 121.709 
                 26.581 
                 26.321 
                 1.00 
                 168.05 
                 C 
               
               
                 HETATM 
                 2417 
                 C6 
                 BMA 
                 A 
                 332 
                 123.071 
                 27.095 
                 25.858 
                 1.00 
                 163.68 
                 C 
               
               
                 HETATM 
                 2418 
                 O6 
                 BMA 
                 A 
                 332 
                 122.918 
                 28.350 
                 25.187 
                 1.00 
                 159.66 
                 O 
               
               
                 HETATM 
                 2419 
                 C4 
                 BMA 
                 A 
                 332 
                 121.806 
                 25.969 
                 27.721 
                 1.00 
                 171.45 
                 C 
               
               
                 HETATM 
                 2420 
                 O4 
                 BMA 
                 A 
                 332 
                 121.940 
                 27.054 
                 28.648 
                 1.00 
                 169.83 
                 O 
               
               
                 HETATM 
                 2421 
                 C3 
                 BMA 
                 A 
                 332 
                 120.602 
                 25.100 
                 28.112 
                 1.00 
                 173.51 
                 C 
               
               
                 HETATM 
                 2422 
                 O3 
                 BMA 
                 A 
                 332 
                 120.940 
                 24.206 
                 29.186 
                 1.00 
                 179.72 
                 O 
               
               
                 HETATM 
                 2423 
                 C2 
                 BMA 
                 A 
                 332 
                 120.106 
                 24.243 
                 26.951 
                 1.00 
                 170.13 
                 C 
               
               
                 HETATM 
                 2424 
                 O2 
                 BMA 
                 A 
                 332 
                 121.018 
                 23.165 
                 26.702 
                 1.00 
                 165.46 
                 O 
               
               
                 HETATM 
                 2425 
                 C1 
                 MAN 
                 A 
                 333 
                 120.952 
                 24.832 
                 30.488 
                 1.00 
                 181.80 
                 C 
               
               
                 HETATM 
                 2426 
                 C2 
                 MAN 
                 A 
                 333 
                 122.387 
                 24.853 
                 31.001 
                 1.00 
                 181.64 
                 C 
               
               
                 HETATM 
                 2427 
                 O2 
                 MAN 
                 A 
                 333 
                 122.457 
                 25.624 
                 32.180 
                 1.00 
                 179.83 
                 O 
               
               
                 HETATM 
                 2428 
                 C3 
                 MAN 
                 A 
                 333 
                 122.877 
                 23.433 
                 31.267 
                 1.00 
                 180.97 
                 C 
               
               
                 HETATM 
                 2429 
                 O3 
                 MAN 
                 A 
                 333 
                 124.163 
                 23.465 
                 31.847 
                 1.00 
                 178.86 
                 O 
               
               
                 HETATM 
                 2430 
                 C4 
                 MAN 
                 A 
                 333 
                 121.903 
                 22.692 
                 32.178 
                 1.00 
                 181.14 
                 C 
               
               
                 HETATM 
                 2431 
                 O4 
                 MAN 
                 A 
                 333 
                 122.278 
                 21.333 
                 32.241 
                 1.00 
                 179.06 
                 O 
               
               
                 HETATM 
                 2432 
                 C5 
                 MAN 
                 A 
                 333 
                 120.464 
                 22.813 
                 31.673 
                 1.00 
                 179.97 
                 C 
               
               
                 HETATM 
                 2433 
                 C6 
                 MAN 
                 A 
                 333 
                 119.472 
                 22.252 
                 32.688 
                 1.00 
                 175.98 
                 C 
               
               
                 HETATM 
                 2434 
                 O6 
                 MAN 
                 A 
                 333 
                 118.313 
                 21.812 
                 32.017 
                 1.00 
                 171.57 
                 O 
               
               
                 HETATM 
                 2435 
                 O5 
                 MAN 
                 A 
                 333 
                 120.127 
                 24.167 
                 31.426 
                 1.00 
                 181.86 
                 O 
               
               
                 HETATM 
                 2436 
                 C1 
                 NAG 
                 A 
                 340 
                 100.888 
                 27.243 
                 −17.586 
                 1.00 
                 88.88 
                 C 
               
               
                 HETATM 
                 2437 
                 C2 
                 NAG 
                 A 
                 340 
                 99.518 
                 26.573 
                 −17.707 
                 1.00 
                 90.13 
                 C 
               
               
                 HETATM 
                 2438 
                 N2 
                 NAG 
                 A 
                 340 
                 99.446 
                 25.405 
                 −18.592 
                 1.00 
                 92.46 
                 N 
               
               
                 HETATM 
                 2439 
                 C7 
                 NAG 
                 A 
                 340 
                 99.882 
                 25.283 
                 −19.848 
                 1.00 
                 92.58 
                 C 
               
               
                 HETATM 
                 2440 
                 O7 
                 NAG 
                 A 
                 340 
                 99.757 
                 24.207 
                 −20.432 
                 1.00 
                 91.08 
                 O 
               
               
                 HETATM 
                 2441 
                 C8 
                 NAG 
                 A 
                 340 
                 100.517 
                 26.438 
                 −20.572 
                 1.00 
                 94.41 
                 C 
               
               
                 HETATM 
                 2442 
                 C3 
                 NAG 
                 A 
                 340 
                 98.440 
                 27.624 
                 −17.910 
                 1.00 
                 89.36 
                 C 
               
               
                 HETATM 
                 2443 
                 O3 
                 NAG 
                 A 
                 340 
                 97.185 
                 26.988 
                 −17.974 
                 1.00 
                 89.82 
                 O 
               
               
                 HETATM 
                 2444 
                 C4 
                 NAG 
                 A 
                 340 
                 98.497 
                 28.556 
                 −16.702 
                 1.00 
                 89.59 
                 C 
               
               
                 HETATM 
                 2445 
                 O4 
                 NAG 
                 A 
                 340 
                 97.691 
                 29.694 
                 −16.929 
                 1.00 
                 94.05 
                 O 
               
               
                 HETATM 
                 2446 
                 C5 
                 NAG 
                 A 
                 340 
                 99.924 
                 29.020 
                 −16.373 
                 1.00 
                 88.48 
                 C 
               
               
                 HETATM 
                 2447 
                 C6 
                 NAG 
                 A 
                 340 
                 99.977 
                 29.712 
                 −15.011 
                 1.00 
                 87.61 
                 C 
               
               
                 HETATM 
                 2448 
                 O6 
                 NAG 
                 A 
                 340 
                 99.455 
                 28.875 
                 −14.001 
                 1.00 
                 84.45 
                 O 
               
               
                 HETATM 
                 2449 
                 O5 
                 NAG 
                 A 
                 340 
                 100.874 
                 27.967 
                 −16.379 
                 1.00 
                 88.47 
                 O 
               
               
                 HETATM 
                 2450 
                 C1 
                 NAG 
                 A 
                 341 
                 96.435 
                 29.594 
                 −16.232 
                 1.00 
                 96.35 
                 C 
               
               
                 HETATM 
                 2451 
                 C2 
                 NAG 
                 A 
                 341 
                 95.794 
                 30.976 
                 −16.163 
                 1.00 
                 96.82 
                 C 
               
               
                 HETATM 
                 2452 
                 N2 
                 NAG 
                 A 
                 341 
                 96.637 
                 31.906 
                 −15.427 
                 1.00 
                 95.78 
                 N 
               
               
                 HETATM 
                 2453 
                 C7 
                 NAG 
                 A 
                 341 
                 97.606 
                 32.617 
                 −16.010 
                 1.00 
                 95.58 
                 C 
               
               
                 HETATM 
                 2454 
                 O7 
                 NAG 
                 A 
                 341 
                 97.874 
                 32.543 
                 −17.210 
                 1.00 
                 95.58 
                 O 
               
               
                 HETATM 
                 2455 
                 C8 
                 NAG 
                 A 
                 341 
                 98.401 
                 33.540 
                 −15.131 
                 1.00 
                 95.35 
                 C 
               
               
                 HETATM 
                 2456 
                 C3 
                 NAG 
                 A 
                 341 
                 94.416 
                 30.892 
                 −15.520 
                 1.00 
                 99.78 
                 C 
               
               
                 HETATM 
                 2457 
                 O3 
                 NAG 
                 A 
                 341 
                 93.789 
                 32.152 
                 −15.588 
                 1.00 
                 99.67 
                 O 
               
               
                 HETATM 
                 2458 
                 C4 
                 NAG 
                 A 
                 341 
                 93.591 
                 29.840 
                 −16.252 
                 1.00 
                 104.00 
                 C 
               
               
                 HETATM 
                 2459 
                 O4 
                 NAG 
                 A 
                 341 
                 92.301 
                 29.715 
                 −15.684 
                 1.00 
                 111.33 
                 O 
               
               
                 HETATM 
                 2460 
                 C5 
                 NAG 
                 A 
                 341 
                 94.327 
                 28.504 
                 −16.243 
                 1.00 
                 102.77 
                 C 
               
               
                 HETATM 
                 2461 
                 C6 
                 NAG 
                 A 
                 341 
                 93.552 
                 27.414 
                 −16.979 
                 1.00 
                 104.49 
                 C 
               
               
                 HETATM 
                 2462 
                 O6 
                 NAG 
                 A 
                 341 
                 93.598 
                 27.650 
                 −18.370 
                 1.00 
                 105.18 
                 O 
               
               
                 HETATM 
                 2463 
                 O5 
                 NAG 
                 A 
                 341 
                 95.577 
                 28.676 
                 −16.876 
                 1.00 
                 98.21 
                 O 
               
               
                 HETATM 
                 2464 
                 C1 
                 BMA 
                 A 
                 342 
                 91.328 
                 30.498 
                 −16.408 
                 1.00 
                 119.64 
                 C 
               
               
                 HETATM 
                 2465 
                 O5 
                 BMA 
                 A 
                 342 
                 91.085 
                 31.765 
                 −15.791 
                 1.00 
                 120.34 
                 O 
               
               
                 HETATM 
                 2466 
                 C5 
                 BMA 
                 A 
                 342 
                 90.208 
                 32.602 
                 −16.547 
                 1.00 
                 121.32 
                 C 
               
               
                 HETATM 
                 2467 
                 C6 
                 BMA 
                 A 
                 342 
                 90.160 
                 33.985 
                 −15.906 
                 1.00 
                 121.40 
                 C 
               
               
                 HETATM 
                 2468 
                 O6 
                 BMA 
                 A 
                 342 
                 91.453 
                 34.603 
                 −16.035 
                 1.00 
                 124.56 
                 O 
               
               
                 HETATM 
                 2469 
                 C4 
                 BMA 
                 A 
                 342 
                 88.838 
                 31.936 
                 −16.610 
                 1.00 
                 123.92 
                 C 
               
               
                 HETATM 
                 2470 
                 O4 
                 BMA 
                 A 
                 342 
                 87.945 
                 32.698 
                 −17.428 
                 1.00 
                 121.93 
                 O 
               
               
                 HETATM 
                 2471 
                 C3 
                 BMA 
                 A 
                 342 
                 88.953 
                 30.537 
                 −17.203 
                 1.00 
                 128.89 
                 C 
               
               
                 HETATM 
                 2472 
                 O3 
                 BMA 
                 A 
                 342 
                 87.672 
                 29.893 
                 −17.113 
                 1.00 
                 140.69 
                 O 
               
               
                 HETATM 
                 2473 
                 C2 
                 BMA 
                 A 
                 342 
                 90.035 
                 29.699 
                 −16.517 
                 1.00 
                 124.67 
                 C 
               
               
                 HETATM 
                 2474 
                 O2 
                 BMA 
                 A 
                 342 
                 89.623 
                 29.265 
                 −15.215 
                 1.00 
                 123.88 
                 O 
               
               
                 HETATM 
                 2475 
                 C1 
                 MAN 
                 A 
                 343 
                 87.247 
                 29.408 
                 −18.403 
                 1.00 
                 151.30 
                 C 
               
               
                 HETATM 
                 2476 
                 C2 
                 MAN 
                 A 
                 343 
                 85.721 
                 29.263 
                 −18.399 
                 1.00 
                 154.03 
                 C 
               
               
                 HETATM 
                 2477 
                 O2 
                 MAN 
                 A 
                 343 
                 85.137 
                 28.979 
                 −19.667 
                 1.00 
                 161.06 
                 O 
               
               
                 HETATM 
                 2478 
                 C3 
                 MAN 
                 A 
                 343 
                 85.324 
                 28.143 
                 −17.439 
                 1.00 
                 150.64 
                 C 
               
               
                 HETATM 
                 2479 
                 O3 
                 MAN 
                 A 
                 343 
                 83.935 
                 27.917 
                 −17.508 
                 1.00 
                 147.95 
                 O 
               
               
                 HETATM 
                 2480 
                 C4 
                 MAN 
                 A 
                 343 
                 86.065 
                 26.864 
                 −17.811 
                 1.00 
                 151.44 
                 C 
               
               
                 HETATM 
                 2481 
                 O4 
                 MAN 
                 A 
                 343 
                 85.807 
                 25.852 
                 −16.867 
                 1.00 
                 146.63 
                 O 
               
               
                 HETATM 
                 2482 
                 C5 
                 MAN 
                 A 
                 343 
                 87.571 
                 27.112 
                 −17.856 
                 1.00 
                 153.70 
                 C 
               
               
                 HETATM 
                 2483 
                 C6 
                 MAN 
                 A 
                 343 
                 88.343 
                 25.860 
                 −18.278 
                 1.00 
                 155.05 
                 C 
               
               
                 HETATM 
                 2484 
                 O6 
                 MAN 
                 A 
                 343 
                 87.459 
                 24.892 
                 −18.810 
                 1.00 
                 158.77 
                 O 
               
               
                 HETATM 
                 2485 
                 O5 
                 MAN 
                 A 
                 343 
                 87.851 
                 28.175 
                 −18.751 
                 1.00 
                 154.50 
                 O 
               
               
                 HETATM 
                 2486 
                 C1 
                 MAN 
                 A 
                 345 
                 85.695 
                 29.622 
                 −20.841 
                 1.00 
                 166.37 
                 C 
               
               
                 HETATM 
                 2487 
                 C2 
                 MAN 
                 A 
                 345 
                 85.634 
                 31.158 
                 −20.781 
                 1.00 
                 167.59 
                 C 
               
               
                 HETATM 
                 2488 
                 O2 
                 MAN 
                 A 
                 345 
                 86.580 
                 31.692 
                 −21.683 
                 1.00 
                 167.20 
                 O 
               
               
                 HETATM 
                 2489 
                 C3 
                 MAN 
                 A 
                 345 
                 84.245 
                 31.731 
                 −21.075 
                 1.00 
                 166.74 
                 C 
               
               
                 HETATM 
                 2490 
                 O3 
                 MAN 
                 A 
                 345 
                 84.322 
                 33.124 
                 −21.288 
                 1.00 
                 162.83 
                 O 
               
               
                 HETATM 
                 2491 
                 C4 
                 MAN 
                 A 
                 345 
                 83.617 
                 31.055 
                 −22.288 
                 1.00 
                 167.34 
                 C 
               
               
                 HETATM 
                 2492 
                 O4 
                 MAN 
                 A 
                 345 
                 82.280 
                 31.482 
                 −22.423 
                 1.00 
                 162.36 
                 O 
               
               
                 HETATM 
                 2493 
                 C5 
                 MAN 
                 A 
                 345 
                 83.684 
                 29.542 
                 −22.101 
                 1.00 
                 168.99 
                 C 
               
               
                 HETATM 
                 2494 
                 C6 
                 MAN 
                 A 
                 345 
                 83.040 
                 28.783 
                 −23.255 
                 1.00 
                 168.07 
                 C 
               
               
                 HETATM 
                 2495 
                 O6 
                 MAN 
                 A 
                 345 
                 83.134 
                 27.399 
                 −22.995 
                 1.00 
                 164.56 
                 O 
               
               
                 HETATM 
                 2496 
                 O5 
                 MAN 
                 A 
                 345 
                 85.042 
                 29.160 
                 −22.008 
                 1.00 
                 168.63 
                 O 
               
               
                 HETATM 
                 2497 
                 C1 
                 MAN 
                 A 
                 344 
                 91.467 
                 35.742 
                 −16.924 
                 1.00 
                 128.05 
                 C 
               
               
                 HETATM 
                 2498 
                 C2 
                 MAN 
                 A 
                 344 
                 92.582 
                 35.574 
                 −17.955 
                 1.00 
                 130.27 
                 C 
               
               
                 HETATM 
                 2499 
                 O2 
                 MAN 
                 A 
                 344 
                 92.454 
                 36.565 
                 −18.952 
                 1.00 
                 128.74 
                 O 
               
               
                 HETATM 
                 2500 
                 C3 
                 MAN 
                 A 
                 344 
                 93.959 
                 35.658 
                 −17.296 
                 1.00 
                 130.86 
                 C 
               
               
                 HETATM 
                 2501 
                 O3 
                 MAN 
                 A 
                 344 
                 94.974 
                 35.677 
                 −18.278 
                 1.00 
                 129.03 
                 O 
               
               
                 HETATM 
                 2502 
                 C4 
                 MAN 
                 A 
                 344 
                 94.078 
                 36.901 
                 −16.419 
                 1.00 
                 129.88 
                 C 
               
               
                 HETATM 
                 2503 
                 O4 
                 MAN 
                 A 
                 344 
                 95.251 
                 36.794 
                 −15.641 
                 1.00 
                 125.41 
                 O 
               
               
                 HETATM 
                 2504 
                 C5 
                 MAN 
                 A 
                 344 
                 92.861 
                 37.074 
                 −15.505 
                 1.00 
                 129.52 
                 C 
               
               
                 HETATM 
                 2505 
                 C6 
                 MAN 
                 A 
                 344 
                 92.875 
                 38.441 
                 −14.825 
                 1.00 
                 129.77 
                 C 
               
               
                 HETATM 
                 2506 
                 O6 
                 MAN 
                 A 
                 344 
                 93.749 
                 38.437 
                 −13.718 
                 1.00 
                 128.61 
                 O 
               
               
                 HETATM 
                 2507 
                 O5 
                 MAN 
                 A 
                 344 
                 91.648 
                 36.961 
                 −16.230 
                 1.00 
                 127.47 
                 O 
               
               
                 HETATM 
                 2508 
                 C1 
                 MAN 
                 A 
                 346 
                 88.141 
                 23.896 
                 −19.600 
                 1.00 
                 161.77 
                 C 
               
               
                 HETATM 
                 2509 
                 C2 
                 MAN 
                 A 
                 346 
                 88.219 
                 24.347 
                 −21.060 
                 1.00 
                 161.25 
                 C 
               
               
                 HETATM 
                 2510 
                 O2 
                 MAN 
                 A 
                 346 
                 89.132 
                 23.525 
                 −21.752 
                 1.00 
                 159.91 
                 O 
               
               
                 HETATM 
                 2511 
                 C3 
                 MAN 
                 A 
                 346 
                 86.856 
                 24.287 
                 −21.743 
                 1.00 
                 161.31 
                 C 
               
               
                 HETATM 
                 2512 
                 O3 
                 MAN 
                 A 
                 346 
                 86.990 
                 24.544 
                 −23.123 
                 1.00 
                 161.03 
                 O 
               
               
                 HETATM 
                 2513 
                 C4 
                 MAN 
                 A 
                 346 
                 86.221 
                 22.919 
                 −21.532 
                 1.00 
                 159.90 
                 C 
               
               
                 HETATM 
                 2514 
                 O4 
                 MAN 
                 A 
                 346 
                 84.913 
                 22.924 
                 −22.053 
                 1.00 
                 159.25 
                 O 
               
               
                 HETATM 
                 2515 
                 C5 
                 MAN 
                 A 
                 346 
                 86.185 
                 22.604 
                 −20.039 
                 1.00 
                 159.17 
                 C 
               
               
                 HETATM 
                 2516 
                 C6 
                 MAN 
                 A 
                 346 
                 85.541 
                 21.251 
                 −19.747 
                 1.00 
                 155.90 
                 C 
               
               
                 HETATM 
                 2517 
                 O6 
                 MAN 
                 A 
                 346 
                 86.162 
                 20.229 
                 −20.493 
                 1.00 
                 152.47 
                 O 
               
               
                 HETATM 
                 2518 
                 O5 
                 MAN 
                 A 
                 346 
                 87.505 
                 22.631 
                 −19.523 
                 1.00 
                 163.55 
                 O