Patent Publication Number: US-2004060081-A1

Title: Plant genes that confer resistance to strains of magnaporthe grisea having avri co39 cultivar specificity gene

Description:
[0001] This application claims priority under 35 U.S.C. §119(e)(1) to U.S. Provisional Application No. 60/242,313, filed Oct. 20, 2000, and to U.S. Provisional Application No. 60/303,897, filed Jul. 9, 2001, the entireties of both of which are incorporated by reference herein. 
    
    
     [0002] Pursuant to 35 U.S.C. §202(c), it is acknowledged that the U.S. Government has certain rights in the invention described herein, which was made in part with funds from the National Institutes of Health (Grant No. GM33716) and the United States Department of Agriculture—Agricultural Research Service (Project Nos.3655-0500-008-00D, 3655-22000-010-00D and 58-3655-7-208). 
    
    
     
       FIELD OF THE INVENTION  
       [0003] This invention relates to the field of disease resistance in plants. In particular, the invention is drawn to novel resistance genes present in rice cultivar CO39 and other plant species, that confers resistance to strains of the rice blast pathogen,  Magnaporthe grisea,  having a corresponding avirulence gene. This invention further provides methods of using the resistance gene and its encoded products for improving resistance of plants to this pathogen.  
       BACKGROUND OF THE INVENTION  
       [0004] Various patent and scientific publications are referred to throughout the specification to describe the state of the art to which this invention pertains. Full citations of such publications not appearing within the specification may be found at the end of the specification. Each of these publications is incorporated by reference herein in its entirety.  
       [0005] Rice is a major staple food for about two-thirds of the world&#39;s population More than ninety percent of the world&#39;s rice is grown and consumed in developing countries. Rice blast disease, caused by the fungus  Magnaporthe grisea , threatens rice crops worldwide. The disease can cause yield losses of ten to thirty percent in infested fields. Rice blast has been an ongoing problem in rice growing areas of the southern United States. It has now become a significant problem in rice growing areas of California, as well.  
       [0006] The “gene-for-gene” hypothesis has been advanced to explain the very specific disease resistance/susceptibility relationship that often exists between races of a plant pathogen and cultivars of its host species. The gene-for-gene hypothesis has been found applicable to many host-pathogen interactions, including that of the rice blast fungus,  Magnaporthe grisea,  and its host,  Oryza sativa . To be able to understand and manipulate this host-pathogen relationship is of great practical interest as  M. grisea  is rapidly able to overcome new disease resistance in rice soon after their deployment. Moreover,  M. grisea  exists as a complex genus with many subspecific groups that are sometimes infertile, but differ in their host range. How these different subspecific groups interrelate evolutionarily is of great concern to plant breeders since some of these alternate hosts are frequently found growing in close proximity to, or in rotation with rice, and  M. grisea  isolates infecting these alternate hosts can sometimes also infect rice.  
       [0007] Gene-for-gene resistance (also known as hypersensitive resistance (KR) or race-specific resistance) depends for its activation on specific recognition of the invading pathogen by the plant. Many individual plant genes have been identified that control gene-for-gene resistance. These genes are referred to as resistance (R) genes. The function of a particular R gene depends on the genotype of the pathogen. A pathogen gene is referred to as an Avr gene if its expression causes the pathogen to produce a signal that triggers a strong defense response in a plant having a corresponding R gene. This response is not observed in the absence of either the Avr gene in the pathogen or the corresponding R gene in the plant. It should be noted that a single plant may have many R genes, and a single pathogen may have many Avr genes. However, strong resistance occurs only when an Avr gene (which is usually a dominant allele) and its corresponding specific R gene (also usually a dominant allele) are matched in a host-pathogen interaction. In this instance, resistance generally occurs as activation of a HR response, in which the cells in the immediate vicinity of the infection undergo programmed necrosis in order to prevent the further advance of the pathogen into living plant tissue. Other features of the resistance response may also include synthesis of antimicrobial metabolites or pathogen-inhibiting enzymes, reinforcement of plant cell walls in the infected area, and induction of signal transduction pathways leading to systemic acquired resistance (SAR) in the plant.  
       [0008] The molecular basis of host-cultivar specificity and pathogenic variability in  M. grisea  has been partly elucidated with the identification, mapping and, in some instances, cloning of specific Avr genes from pathogenic isolates of  M. grisea.  For instance, AVR2-YAMO (more recently named Avr-Pita)(cultivar specificity) and PWL2 (host specificity) (Valent &amp; Chumley, pp. 3.113-3.134 in  Rice Blast Disease  (R. Zeigler, S. A. Leong, P. Teng, Eds.), Wallingford: CAB International, 1994) both function as classic avirulence genes by preventing infection of a specific cultivar or host. AVR2-YAMO encodes a 223-amino acid protein with homology to proteases, while PWL2 encodes a 145-amino acid polypeptide which is glycine-rich. Based on the predicted amino acid sequences of the proteins, both may be secreted (Sweigard et al., Plant Cell 7:1221-1233, 1995).  
       [0009] Homologs of both AVR2-YAMO and PWL2 appear to be widely distributed in rice and in other grass-infecting isolates of  M. grisea , thereby confirming that  M. grisea  isolates which do not infect rice still may carry host or cultivar specificity genes for rice. In some cases, homologs of AVR2-YAMO and PWL2 have been shown to be functional and to exhibit the same host or cultivar specificity as AVR2-YAMO or PWL2 (Kang et al., Molecular Plant-Microbe Interactions. 8:939-498, 1995; Orbach et al., Plant Cell. 12:2019-2032, 2000;.Jia et al., EMBO J 12:4004-4014, 2000).  
       [0010] As another example of a potentially useful Avr gene, the cultivar specificity gene AVR1-CO39, which determines avirulence on rice cultivar CO39, has been identified (Valent et al., Genetics 127: 87-101, 1991) and mapped to a position on  M. grisea  chromosome 1 (Smith &amp; Leong, Theor. Appl. Genet. 88: 901-908, 1994). The avirulence gene in  M. grisea  (AVR1-CO39) has been cloned and sequenced (Farman &amp; Leong, 1998; see also PCT US99/04047 and commonly-owned co-pending U.S. application Ser. No. 09/257,585).  
       [0011] Indica rice cultivar CO39 was originally bred for blast resistance and agronomic value and has been lately used as a tester for blast pathogenicity assays as well as a recurrent parent for developing near-isogenic-lines. Genetic analysis of blast resistance in CO39 to  M. grisea  progeny, 6082, which carries AVR1-CO39, as well as to the Guy 11(AVR1-CO39) transformant has shown that resistance is controlled by a single dominant locus. The resistance phenotype is uniform and consistently of reaction type 1 and is inherited as a simple Mendelian trait among different segregating populations (F1/F2/F3/F4). The resistance gene(s), designated as Pi-CO39(t), has been mapped to the short arm of rice chromosome 11. However, neither fine mapping nor cloning of the Pi-CO39(t) locus has been reported.  
       [0012] In addition to cloned cultivar and host specificity genes from  M. grisea , the availability of the corresponding R genes from rice would provide usefuil tools for manipulating and augmenting resistance to this pathogen in the field. Accordingly, it is an object of the present invention to provide a new cloned rice R gene that confers resistance to strains of  Magnaporthe grisea  carrying the AVR1-CO39 avirulence gene. It is a further object of the present invention to provide methods for using the R gene and the corresponding fungal avirulence gene to confer or improve resistance of other cultivars and plant species to rice blast and other plant diseases.  
       SUMMARY OF THE INVENTION  
       [0013] One aspect of the invention features an isolated nucleic acid segment from chromosome 11 of Indica rice cultivar CO39, which comprises one or more genes that confer resistance to strains of the rice blast pathogen,  Magnaporthe grisea,  that have the avirulence gene AVR1-CO39. The locus comprising the gene(s) co-segregates with one or more of the following markers: (1) RGA8 (GenBank Accession No. AF074889; Mago et al., 1999); (2) RGA38 (GenBank Accession No. AF074895; Mago et al., 1999); and (3) G320 (GenBank Accession No. RICG320A Fukuoka et al., 1994). The gene (or, if more than one, the plurality of genes) is referred to herein as Pi-CO39(t). It should be noted that the term Pi-CO39(t) gene, if used in the singular herein, also refers to any plurality of genes associated with resistance to AVR1-CO39expressing strains of  M. grisea.    
       [0014] According to another aspect of the invention, a transgenic plant comprising the Pi-CO39(t) resistance gene is provided. Expression of the gene in the transgenic plants confers a resistance response upon challenge with the gene product of AVR1-CO39 or microorganisms expressing the AVR1-CO39 gene. In a preferred embodiment, the plant is rice. In another embodiment, the plant is a monocot other than rice, which is susceptible to diseases caused by Magnaporthe. Such plants include, for example, turf grasses such as  Lolium perenne.  In another embodiment, the plant is a dicotyledenous species.  
       [0015] According to another aspect of the invention, a method of enhancing pathogen resistance in a plant is provided. The method comprises the following steps: (1) transforming the plant with the Pi-CO39(t) gene; and (2) pre-treating the transformed plant with either the AVR1-CO39 gene product or a non-pathogenic organism (e.g., an epiphytic bacterium or a non-pathogenic fungus) that expresses a portion of an AVR1-CO39 gene effective to trigger expression of a CO39-specific R gene in the plants. Triggering expression of the R gene in this manner will confer upon the plant increased resistance not only to  Magnaporthe grisea,  but also to other plant pathogens whose infective ability is reduced or prevented by the R gene product and its associated activity.  
       [0016] These and other features and advantages of the present invention will be described in greater detail in the description and examples set forth below. 
     
    
    
     BRIEF DESCRIPTION OF THE DRAWINGS  
     [0017]FIG. 1. Schematic diagrams showing a genetic map linked with physical maps of a region of rice chromosome 11-associated with Pi-CO39 (t). The genetic map displays the resistance gene(s), Pi-CO39(t) with respect to co-segregating markers. Designations to the right of the schematic diagram of chromosome 11 of rice CO39 are names of genetic markers. Numbers to the left represent distance in centiMorgans (cM). The physical map is from Japonica rice variety, Nipponbare and Indica rice variety CO39. The physical map shows minimum tiling path of BAC clones from Contig 43 of a BAC library from Japonica rice variety, Nipponbare and its relationship to a contig of BAC clones from Indica rice variety CO39.  
     [0018]FIG. 2. Diagram showing comparative sequence analysis of BAC clones from variety Nipponbare (Japonica, susceptible) and CO39 (Indica, resistant) at regions that cosegregate with Pi-CO39 (t). NSL (Nipponbare serpin-like genes); CSL (CO39 serpin-like genes); NBR (Nipponbare NBS-LRR disease resistance-like genes); CODR (CO39 NBS-LRR disease resistance-like genes); note NBR2 is a rice Pib-like gene; NBR3, NBR5 and CODR4 are rice Pi-ta-like genes; KIN1 and KIN2 are receptor kinases; CODR3 is a rice Xa1-like gene; another CODR gene, homologous to NBR1 or NBR2, may exist between CSL3 and CODR1 on E2P5; and the solid bars indicate retroelements.  
     DETAILED DESCRIPTION OF THE INVENTION  
     [0019] I. Definitions  
     [0020] Various terms relating to the biological molecules of the present invention are used hereinabove and also throughout the specifications and claims.  
     [0021] The term “pathogen-inoculated” refers to the inoculation of a plant with a pathogen.  
     [0022] The term “disease defense response” refers to a change in metabolism, biosynthetic activity or gene expression that enhances the plant&#39;s ability to suppress the replication and spread of a microbial pathogen (i.e., to resist the microbial pathogen). Examples of plant disease defense responses include, but are not limited to, production of low molecular weight compounds with antimicrobial activity (referred to as phytoalexins) and induction of expression of defense (or defense-related) genes, whose products include, for example, peroxidases, cell wall proteins, proteinase inhibitors, hydrolytic enzymes, pathogenesis-related (PR) proteins and phytoalexin biosynthetic enzymes, such as phenylalanine ammonia lyase and chalcone synthase. Such defense responses appear to be induced in plants by several signal transduction pathways involving secondary defense signaling molecules produced in plants. Agents that induce disease defense responses in plants include, but are not limited to: (1) microbial pathogens, such as fungi, bacteria and viruses; (2) microbial components and other defense response elicitors, such as proteins and protein fragments, small peptides, β-glucans, elicitins and harpins, cryptogein and oligosaccharides; and (3) secondary defense signaling molecules produced by the plant, such as salicylic acid, H 2 O 2 , nitric oxide, ethylene and jasmonates.  
     [0023] With reference to nucleic acids of the invention, the term “isolated nucleic acid” or “polynucleotide” is sometimes used. This term, when applied to DNA, refers to a DNA molecule that is separated from sequences with which it is immediately contiguous (in the 5′ and 3′ directions) in the naturally occurring genome of the organism from which it was derived. For example, the “isolated nucleic acid” may comprise a DNA molecule inserted into a vector, such as a plasmid or virus vector, or integrated into the genomic DNA of a procaryote or eucaryote. An “isolated nucleic acid molecule” may also comprise a cDNA molecule.  
     [0024] With respect to RNA molecules of the invention the term “isolated nucleic acid” or “polynucleotide” primarily refers to an RNA molecule encoded by an isolated DNA molecule as defined above. Alternatively, the term may refer to an RNA molecule that has been sufficiently separated from RNA molecules with which it would be associated in its natural state (i.e., in cells or tissues), such that it exists in a “substantially pure” form (the term “substantially pure” is defined below).  
     [0025] With respect to protein, the term “isolated protein” or “isolated and purified protein” is sometimes used herein. This term refers primarily to a protein produced by expression of an isolated nucleic acid molecule of the invention. Alternatively, this term may refer to a protein which has been sufficiently separated from other proteins with which it would naturally be associated, so as to exist in “substantially pure” form.  
     [0026] With respect to antibodies of the invention, the term “immunologically specific” refers to antibodies that bind to one or more epitopes of a protein of interest, but which do not substantially recognize and bind other molecules in a sample containing a mixed population of antigenic biological molecules.  
     [0027] The term “substantially pure” refers to a preparation comprising at least 50-60% by weight the compound of interest (e.g., nucleic acid, oligonucleotide, protein, etc.). More preferably, the preparation comprises at least 75% by weight, and most preferably 90-99% by weight, the compound of interest Purity is measured by methods appropriate for the compound of interest (e.g. chromatographic methods, agarose or polyacrylamide gel electrophoresis, HPLC analysis, and the like).  
     [0028] When used herein in describing components of media or other experimental results, the term “about” means within a margin of commonly acceptable error for the determination being made, using standard methods. For plant transformation or tissue culture media in particular, persons skilled in the art would appreciate that the concentrations of various components initially added to culture media may change somewhat during use of the media, e.g., by evaporation of liquid from the medium or by condensation onto the medium. Moreover, it is understood that the precise concentrations of the macronutrients, vitamins and carbon sources are less critical to the efficacy of the media than are the micronutrient, hormone and antibiotic concentrations.  
     [0029] With respect to single stranded oligonucleotides and polynucleotides, the term “specifically hybridizing” refers to the association between two single-stranded nucleotide molecules of sufficiently complementary sequence to permit such hybridization under pre-determined conditions generally used in the art (sometimes termed “substantially complementary”). In particular, the term refers to hybridization of an oligonucleotide or polynucleotide with a substantially complementary sequence contained within a single-stranded DNA or RNA molecule of the invention, to the substantial exclusion of hybridization of the oligonucleotide or polynucleotide with single-stranded nucleic acids of non-complementary sequence.  
     [0030] The term “substantially the same” refers to nucleic acid or amino acid sequences having sequence variation that do not materially affect the nature of the protein (i.e. the structure, stability characteristics and/or biological activity of the protein). With particular reference to nucleic acid sequences, the term “substantially the same” is intended to refer to the coding region and to conserved sequences governing expression, and refers primarily to degenerate codons encoding the same amino acid, or alternate codons encoding conservative substitute amino acids in the encoded polypeptide. With reference to amino acid sequences, the term “substantially the same” refers generally to conservative substitutions and/or variations in regions of the polypeptide not involved in determination of structure or function.  
     [0031] Nucleic acid sequences and amino acid sequences can be compared using computer programs that align the similar sequences of the nucleic or amino acids thus define the differences. In preferred methodologies, the Blastn and Blastp 2.0 programs provided by the National Center for Biotechnology Information (at www.ncbi.nlm.nih.gov/blast/: Altschul et al., 1990, J. Mol. Biol. 215:403-410) using a gapped alignment with default parameters, may be used to determine the level of identity and similarity between nucleic acid sequences and amino acid sequences. However, equivalent alignments and similarity/identity assessments can be obtained through the use of any standard alignment software. For instance, the DNAstar system (Madison, Wis.) may be used to align sequence fragments of genomic or other DNA sequences. Alternatively, GCG Wisconsin Package version 9.1, available from the Genetics Computer Group in Madison, Wis., and the default parameters used (gap creation penalty=12, gap extension penalty=4) by that program may also be used to compare sequence identity and similarity.  
     [0032] The terms “percent identical” and “percent similar” are also used herein in comparisons among amino acid and nucleic acid sequences. When referring to amino acid sequences, “percent identical” refers to the percent of the amino acids of the subject amino acid sequence that have been matched to identical amino acids in the compared amino acid sequence by a sequence analysis program. “Percent similar” refers to the percent of the amino acids of the subject amino acid sequence that have been matched to identical or conserved amino acids. Conserved amino acids are those which differ in structure but are similar in physical properties such that the exchange of one for another would not appreciably change the tertary structure of the resulting protein. Conservative substitutions are defined by Taylor (1986, J. Theor. Biol. 119:205). Polypeptides having sequences greater than 70% identical, preferably greater than 80%, and more preferably greater than 90% and most preferably greater than 95% identical to the polypeptides encoded by the nucleic acid sequences described herein are considered within the scope of the invention. When referring to nucleic acid molecules, “percent identical” refers to the percent of the nucleotides of the subject nucleic acid sequence that have been matched to identical nucleotides by a sequence analysis program. Polynucleotides having sequences greater than 60% identical, preferably greater than 70% identical, more preferably preferably greater than 80% identical, and more preferably greater than 90% identical, and most preferably greater than 95% identical to the polynucleotides described herein are considered within the scope of the invention.  
     [0033] A “coding sequence” or “coding region” refers to a nucleic acid molecule having sequence information necessary to produce a gene product (RNA or protein), when the sequence is expressed.  
     [0034] The term “operably linked” or “operably inserted” means that the regulatory sequences necessary for expression of the coding sequence are placed in a nucleic acid molecule in the appropriate positions relative to the coding sequence so as to enable expression of the coding sequence. This same definition is sometimes applied to the arrangement of other transcription control elements (e.g. enhancers) in an expression vector.  
     [0035] Transcriptional and translational control sequences, sometimes referred to herein as “expression control” sequences or elements, or “expression regulating” sequences or elements, are DNA regulatory elements such as promoters, enhancers, ribosome binding sites, polyadenylation signals, terminators, and the like, that provide for the expression of a coding sequence in a host cell. The term “expression” is intended to include transcription of DNA and translation of the mRNA transcript.  
     [0036] The terms “promoter”, “promoter region” or “promoter sequence” refer generally to transcriptional regulatory regions of a gene, which may be found at the 5′ or 3′ side of the coding region, or within the coding region, or within introns. Typically, a promoter is a DNA regulatory region capable of binding RNA polymerase in a cell and initiating transcription of a downstream (3′ direction) coding sequence. The typical 5′ promoter sequence is bounded at its 3′ terminus by the transcription initiation site and extends upstream (5′ direction) to include the minimum number of bases or elements necessary to initiate transcription at levels detectable above background. Within the promoter sequence is a transcription initiation site (conveniently defined by mapping with nuclease S1), as well as protein binding domains (consensus sequences) responsible for the binding of RNA polymerase.  
     [0037] A “vector” is a replicon, such as plasmid, phage, cosmid, or virus to which another nucleic acid segment may be operably inserted so as to bring about the replication or expression of the segment.  
     [0038] The term “nucleic acid construct” or “DNA construct” is sometimes used to refer to a coding sequence or sequences operably linked to appropriate regulatory sequences and inserted into a vector for transforming a cell. This term may be used interchangeably with the term “transforming DNA”. Such a nucleic acid construct may contain a coding sequence for a gene product of interest, along with a selectable marker gene and/or a reporter gene. These constructs may be administered to plants in a viral or plasmid vector. Other methods of delivery such as Agrobacterium T-DNA mediated transformation and transformation using the biolistic process are also contemplated to be within the scope of the present invention. In addition to specific methods described herein, the transforming DNA may be prepared according to standard protocols such as those set forth in “Current Protocols in Molecular Biology”, eds. Frederick M. Ausubel et al., John Wiley &amp; Sons, 2001. In certain embodiments, such constructs are chimeric, i.e., the coding sequence is from a different source one or more of the regulatory sequences (e.g., coding sequence from rice and promoter from maize or Arabidopsis). However, non-chimeric DNA constructs also can be used. A plant species or cultivar may be transformed with a DNA construct (chimeric or non-chimeric) that encodes a polypeptide from a different plant species or cultivar, or a non-plant species. Alternatively, a plant species or cultivar may be transformed with a DNA construct (chimeric or non-chimeric) that encodes a polypeptide from the same plant species or cultivar. The term “transgene” is sometimes used to refer to the DNA construct within the transformed cell or plant.  
     [0039] The term “selectable marker gene” refers to a gene encoding a product that, when expressed, confers a selectable phenotype such as antibiotic resistance on a transformed cell.  
     [0040] The term “reporter gene” refers to a gene that encodes a product which is easily detectable by standard methods, either directly or indirectly.  
     [0041] A “heterologous” region of a nucleic acid construct is an identifiable segment (or segments) of the nucleic acid molecule within a larger molecule that is not found in association with the larger molecule in nature. Thus, when the heterologous region encodes a plant gene, the gene will usually be flanked by DNA that does not flank the plant genomic DNA in the genome of the source organism. In another example, a heterologous region is a construct where the coding sequence itself is not found in nature (e.g., a cDNA where the genomic coding sequence contains introns, or synthetic sequences having codons different than the native gene). Allelic variations or naturally occurring mutational events do not give rise to a heterologous region of DNA as defined herein. The term “DNA construct”, as defined above, is also used to refer to a heterologous region, particularly one constructed for use in transformation of a cell.  
     [0042] A cell has been “transformed” or “transfected” by exogenous or heterologous DNA when such DNA has been introduced inside the cell. The transforming DNA may or may not be integrated (covalently linked) into the genome of the cell. In prokaryotes, yeast, and plant or animal cells for example, the transforming DNA may be maintained on an episomal element such as a plasmid. With respect to eukaryotic cells, a stably transformed cell is one in which the transforming DNA has become integrated into a chromosome so that it is inherited by daughter cells through chromosome replication. This stability is demonstrated by the ability of the eukaryotic cell to establish cell lines or clones comprised of a population of daughter cells containing the transforming DNA. A “clone” is a population of cells derived from a single cell or common ancestor by mitosis. A “cell line” is a clone of a primary cell that is capable of stable growth in vitro for many generations.  
     [0043] II. Description  
     [0044] In accordance with the present invention, a novel rice resistance gene (or genes) has been identified and localized to a specific region on chromosome 11 of the rice genome. This gene is referred to herein as Pi-CO39(t), to denote its function as a gene in rice cultivar CO39 that confers resistance to strains of the plant pathogen,  Magnaporthe grisea,  that contain the cultivar specificity gene AVR1-CO39.  
     [0045] The genetic mapping of Pi-CO39(t) in rice line CO39 and identification of large insert clones linked to resistance are described in detail in Example 1. The gene was mapped to 5.9 cM from marker RG1094 and 1.0 cM from marker S2712 on chromosome 11 in 260 F2 progenies. Three additional markers, RGA8, RGA38 and G320, were found to co-segregate with the Pi-CO39(t) gene in 400 F2 progenies among 1,100 F2 progenies phenotypically tested for resistance. These markers were used to isolate BAC clones from the resistant variety CO39 and the susceptible variety Nipponbare. Single BAC clones hybridizing to all co-segregating markers were obtained from the Nipponbare library; these are clones 82N20, 55L08, 20A20, 5M17. Several BAC clones hybridizing to co-segregating marker RGA38 were obtained from the CO39 library; these are clones 1L23, 36K6,4A14. Sequence analysis of the RGA38 and RGA8 homologs in CO39 yielded SEQ ID NO: 1 and SEQ ID NO:2, respectively. These two sequences are about 97% and 84% identical, respectively, to RGA38 and RGA8 as reported by Mago et al. (GenBank Accession Numbers set forth above).  
     [0046] It is believed that part or all of the genomic region of rice containing Pi-CO39(t) resides on one or more of the CO39 BAC clones listed above. A contig of about 0.5 mb has been constructed in the relevant region of the Nipponbare library. Sequence information of portions of the Nipponbare contig is set forth in Example 2 as SEQ ID NOS: 3 and 4. Sequences of two BAC clones, K6P36 and E2P5, from the relevant region of CO39 chromosome 11 are set forth herein as SEQ ID NO:5 and SEQ ID NO:6. A detailed analysis of the BAC clones and the genes predicted to be located on the clones is also set forth in the examples. Sequences representing the open reading frames of BAC clones K6P36 and E2P5 are set forth as SEQ ID NOS: 7-14, and described in FIG. 2 and in the examples.  
     [0047] The following description sets forth the general procedures involved in practicing the present invention. To the extent that specific materials are mentioned, it is merely for purposes of illustration and is not intended to limit the invention Unless otherwise specified, general cloning procedures, such as those set forth in Sambrook et al.,  Molecular Cloning,  Cold Spring Harbor Laboratory (1989) (hereinafter “Sambrook et al.”) or Ausubel et al. (eds)  Current Protocols in Molecular Biology,  John Wiley &amp; Sons (2001) (hereinafter “Ausubel et al.”) are used.  
     A. Preparation of Pi-CO39(t) Nucleic Acid M lecules, Encoded P lypeptides and Transgenic Plants  
     [0048] 1. Nucleic Acid Molecules  
     [0049] Pi-CO39(t) nucleic acid molecules of the invention may be prepared by two general methods: (1) they may be synthesized from appropriate nucleotide triphosphates, or (2) they may be isolated from biological sources. Both methods utilize protocols well known in the art.  
     [0050] The availability of the Pi-CO39(t) nucleotide sequence information enables preparation of an isolated nucleic acid molecule of the invention by oligonucleotide synthesis. Synthetic oligonucleotides may be prepared by the phosphoramadite method employed in the Applied Biosystems 38A DNA Synthesizer or similar devices. The resultant construct may be purified according to methods known in the art, such as high performance liquid chromatography (HPLC).  
     [0051] Pi-CO39(t) genes also may be isolated from appropriate biological sources using methods known in the art. In one embodiment, large insert clones have been isolated from BAC libraries of a resistant and susceptible rice cultivar. In an alternative embodiment, a cDNA clone comprising the open reading frame of the genomic Pi-CO39(t) locus may be isolated.  
     [0052] In accordance with the present invention, nucleic acids having the appropriate level sequence homology with part or all the coding and/or regulatory regions of Pi-CO39(t) may be identified by using hybridization and washing conditions of appropriate stringency. For example, hybridizations may be performed, according to the method of Sambrook et al., using a hybridization solution comprising: 5×SSC, 5× Denhardt&#39;s reagent, 1.0% SDS, 100 μg/ml denatured, fragmented salmon sperm DNA, 0.05% sodium pyrophosphate and up to 50% formamide. Hybridization is carried out at 37-42° C. for at least six hours. Following hybridization, filters are washed as follows: (1) 5 minutes at room temperature in 2×SSC and 1% SDS; (2) 15 minutes at room temperature in 2×SSC and 0.1% SDS; (3) 30 minutes-1 hour at 37° C. in 2×SSC and 0.1% SDS; (4) 2 hours at 45-55° in 2×SSC and 0.1% SDS, changing the solution every 30 minutes. Alternatively, a modification of the Amasino hybridization protocol (Anal. Biochem. 152: 304-307) is preferred for use in the present invention and is described in greater detail in Example 1.  
     [0053] One common formula for calculating the stringency conditions required to achieve hybridization between nucleic acid molecules of a specified sequence homology (Sambrook et al., 1989):  
       T   m =81.5° C.+16.6 Log [Na+]+0.41(%  G+C )−0.63 (% formamide)−600/#bp in duplex 
     [0054] As an illustration of the above formula, using [N+]=[0.368] and 50% formamide, with GC content of 42% and an average probe size of 200 bases, the T m  is 57° C. The T m  of a DNA duplex decreases by 1-1.5° C. with every 1% decrease in homology. Thus, targets with greater than about 75% sequence identity would be observed using a hybridization temperature of 42° C. In a preferred embodiment, the hybridization is at 37° C. and the final wash is at 42° C., in a more preferred embodiment the hybridization is at 42° C. and the final wash is at 50° C., and in a most preferred embodiment the hybridization is at 42° C. and final wash is at 65° C., with the above hybridization and wash solutions. Conditions of high stringency include hybridization at 42° C. in the above hybridization solution and a final wash at 65° C. in 0.1×SSC and 0.1% SDS for 10 minutes.  
     [0055] Nucleic acids of the present invention may be maintained as DNA in any convenient cloning vector. In a preferred embodiment, clones are maintained in plasmid cloning/expression vector, such as pGEM-T (Promega Biotech, Madison, Wis.) or pBluescript (Stratagene, La Jolla, Calif.), either of which is propagated in a suitable  E. coli  host cell.  
     [0056] Pi-CO39(t) nucleic acid molecules of the invention include cDNA, genomic DNA, RNA, and fragments thereof which may be single- or double-stranded. Thus, this invention provides oligonucleotides (sense or antisense strands of DNA or RNA) having sequences capable of hybridizing with at least one sequence of a nucleic acid molecule of the present invention. Such oligonucleotides are useful as probes for detecting Pi-CO39(t) genes or mRNA in test samples of plant tissue, e.g. by PCR amplification, or for the positive or negative regulation of expression of Pi-CO39(t) genes at or before translation of the mRNA into proteins.  
     [0057] 2. Polypeptides  
     [0058] Polypeptides encoded by the Pi-CO39(t) gene may be prepared in a variety of ways, according to known methods. If produced in situ the polypeptides may be purified from appropriate sources, e.g., plant tissue.  
     [0059] Alternatively, the availability of nucleic acid molecules encoding the polypeptides will enable production of the proteins using in vitro expression methods known in the art. For example, a cDNA or gene may be cloned into an appropriate in vitro transcription vector, such a pSP64 or pSP65 for in vitro transcription, followed by cell-free translation in a suitable cell-free translation system, such as wheat germ or rabbit reticulocytes. In vitro transcription and translation systems are commercially available, e.g., from Promega Biotech, Madison, Wis. or BRL, Rockville, Md.  
     [0060] According to a preferred embodiment, larger quantities of Pi-CO39(t)-encoded polypeptides may be produced by expression in a suitable procaryotic or eucaryotic system. For example, part or all of a Pi-CO39(t) gene or cDNA may be inserted into a plasmid vector adapted for expression in a bacterial cell (such as  E. coli ) or a yeast cell (such as  Saccharomyces cerevisiae ), or into a baculovirus vector for expression in an insect cell. Such vectors comprise the regulatory elements necessary for expression of the DNA in the host cell, positioned in such a manner as to permit expression of the DNA in the host cell. Such regulatory elements required for expression include promoter sequences, transcription initiation sequences and, optionally, enhancer sequences.  
     [0061] The Pi-CO39(t) polypeptide(s) produced by gene expression in a recombinant procaryotic or eucyarotic system may be purified according to methods known in the art. In a preferred embodiment, a commercially available expression/secretion system can be used, whereby the recombinant protein is expressed and theater secreted from the host cell, to be easily purified from the surrounding medium. If expression/secretion vectors are not used, an alternative approach involves purifying the recombinant protein by affinity separation, such as by immunological interaction with antibodies that bind specifically to the recombinant protein. Such methods are commonly used by skilled practitioners.  
     [0062] The present invention also provides antibodies capable of immunospecifically binding to Pi-CO39(t)-encoded polypeptides. Polyclonal or monoclonal antibodies are prepared according to standard methods. Monoclonal antibodies may be prepared according to general methods of Köhler and Milstein, following standard protocols. Recombinant monoclonal antibodies also may be prepared in accordance with standard methods, e.g., via phage display libraries of genes encoding human or animal antibodies or fragments, which may be panned with plant proteins. In a preferred embodiment, antibodies are prepared, which react immunospecifically with various epitopes of the Pi-CO39(t)-encoded polypeptides.  
     [0063] Polyclonal or monoclonal antibodies that immunospecifically interact with one or more of the polypeptides encoded by Pi-CO39(t) can be utilized for identifying and purifying such proteins. For example, antibodies may be utilized for affinity separation of proteins with which they immunospecifically interact. Antibodies may also be used to immunoprecipitate proteins from a sample containing a mixture of proteins and other biological molecules.  
     [0064] 3. Transgenic Plants  
     [0065] The present invention includes transgenic plants comprising one or more copies of the Pi-CO39(t) gene or genes. This is accomplished by transforming plant cells with a transgene that comprises part of all of a Pi-CO39(t) coding sequence, controlled by either native or recombinant regulatory sequences, as described below. Transgenic plants of any species are included in the invention. Preferred are monocots having susceptibility to pathogenic species of Magnaporthe; these include rice, wheat, barley, maize and other cereal crops, as well as turfgrasses such as  Lolium perenne  L.,  Lolium multiflorium  Lam. and the cereal  Setaria italica.    
     [0066] Transgenic plants can be generated using standard plant transformation methods known to those skilled in the art. These include, but are not limited to, Agrobacterium vectors, polyethylene glycol treatment of protoplasts, biolistic DNA delivery, UV laser microbeam, gemini virus vectors or other plant viral vectors, calcium phosphate treatment of protoplasts, electroporation of isolated protoplasts, agitation of cell suspensions in solution with microbeads coated with the transforming DNA, agitation of cell suspension in solution with silicon fibers coated with transforming DNA, direct DNA uptake, liposome-mediated DNA uptake, and the like. Such methods have been published in the art. See, e.g.,  Methods for Plant Molecular Biology  (Weissbach &amp; Weissbach, eds., 1988);  Methods in Plant Molecular Biology  (Schuler &amp; Zielinski, eds., 1989);  Plant Molecular Biology Manual  (Gelvin, Schilperoort, Verma, eds., 1993); and  Methods in Plant Molecular Biology—A Laboratorv Manual  (Maliga, Klessig, Cashmore, Gruissem &amp; Varner, eds., 1994).  
     [0067] The method of transformation depends upon the plant to be transformed. Agrobacterium vectors are often used to transform dicot species. Agrobacterium binary vectors include, but are not limited to, BIN19 (Bevan, 1984) and derivatives thereof, the pBI vector series (Jefferson et al., 1987), and binary vectors pGA482 and pGA492 (An, 1986) For transformation of monocot species, biolistic bombardment with particles coated with transforming DNA and silicon fibers coated with transforming DNA are often useful for nuclear transformation. Alternatively, Agrobacterium “superbinary” vectors have been used successfully for the transformation of rice, maize and various other monocot species.  
     [0068] DNA constructs for transforming a selected plant comprise a coding sequence of interest operably linked to appropriate 5′ (e.g., promoters and translational regulatory sequences) and 3′ regulatory sequences (e.g., terminators). In a preferred embodiment, the Pi-CO39(t) gene under control of its own 5′ and 3′ regulatory elements is utilized.  
     [0069] In an alternative embodiment, the coding region of the gene is placed under a powerful constitutive promoter, such as the Cauliflower Mosaic Virus (CaMV) 35S promoter or the figwort mosaic virus 35S promoter. Other constitutive promoters contemplated for use in the present invention include, but are not limited to: T-DNA mannopine synthetase, nopaline synthase (NOS) and octopine syntiase (OCS) promoters. In preferred embodiments, a strong monocot promoter is used, for example, the maize ubiquitin promoter, the rice actin promoter or the rice tubulin promoter (Jeon et al., Plant Physiology. 123:1005-14, 2000).  
     [0070] Transgenic plants expressing Pi-CO39(t) coding sequences under an inducible promoter are also contemplated to be within the scope of the present invention. Inducible plant promoters include the tetracycline repressor/operator controlled promoter, the heat shock gene promoters, stress (e.g., wounding)-induced promoters, defense responsive gene promoters (e.g. phenylalanine ammonia lyase genes), wound induced gene promoters (e.g. hydroxyproline rich cell wall protein genes), chemically-inducible gene promoters (e.g., nitrate reductase genes, glucanase genes, chitanase genes, etc.) and dark-inducible gene promoters (e.g., asparagine synthetase gene) to name a few. The use of pathogen- and wound-inducible promoters is described in more detail below.  
     [0071] Tissue specific and development-specific promoters are also contemplated for use in the present invention. Examples of these include, but are not limited to: the ribulose bisphosphate carboxylase (RuBisCo) small subunit gene promoters or chlorophyll a/b binding protein (CAB) gene promoters for expression in photosynthetic tissue; the various seed storage protein gene promoters for expression in seeds; and the root-specific glutamine synthetase gene promoters where expression in roots is desired.  
     [0072] The coding region is also operably linked to an appropriate 3′ regulatory sequence. In a preferred embodiment, the nopaline synthetase polyadenylation region (NOS) is used. Other useful 3′ regulatory regions include, but are not limited to the octopine (OCS) polyadenylation region.  
     [0073] Using an Agrobacterium binary vector system for transformation, the selected coding region, under control of appropriate regulatory elements, is linked to a nuclear drug resistance marker, such as kanamycin resistance. Other useful selectable marker systems include, but are not limited to: other genes that confer antibiotic or herbicide resistances (e.g., resistance to hygromycin or bialaphos) or herbicide resistance (e.g., resistance to sulfonylurea, phosphinothricin, or glyphosate).  
     [0074] Plants are transformed and thereafter screened for one or more properties, including the presence of Pi-CO39(t) protein, Pi-CO39(t) mRNA, or enhanced resistance to plant pathogens, in particular  Magnaporthe grisea.  It should be recognized that the amount of expression, as well as the tissue-specific pattern of expression of the transgenes in transformed plants can vary depending on the position of their insertion into the nuclear genome. Such positional effects are well known in the art. For this reason, several nuclear transformants should be regenerated and tested for expression of the transgene.  
     [0075] Transgenic plants that exhibit one or more of the aforementioned desirable phenotypes can be used for plant breeding, or directly in agricultural or horticultural applications. Plants containing one transgene may also be crossed with plants containing a complementary transgene in order to produce plants with enhanced or combined phenotypes.  
     B. Uses of Pi-CO39(t) Nucleic Acids, Proteins and Transgenic Plants  
     [0076] The potential of recombinant genetic engineering methods to enhance disease resistance in agronomically important plants has received considerable attention in recent years. Protocols are currently available for the stable introduction of genes into plants (as described in detail above), as well as for augmentation of gene expression. The present invention provides nucleic acid molecules which, upon stable introduction into a recipient plant, can enhance the plant&#39;s ability to resist pathogen attack.  
     [0077] 1. Pi-CO39(t) Nucleic Acids and Transgenic Plants  
     [0078] Pi-CO39(t) nucleic acids (genomic clones or cDNAs) may be used fov a variety of purposes in accordance with the present invention. The DNA, RNA, or fragments thereof may be used as probes to detect the presence of and/or expression of Pi-CO39(t) genes. Methods in which Pi-CO39(t) 19Unucleic acids may be utilized as probes for such assays include, but are not limited to: (1) in situ hybridization; (2) Southern hybridization (3) northern hybridization; and (4) assorted amplification reactions such as polymerase chain reactions (PCR). The Pi-CO39(t) nucleic acids of the invention may also be utilized as probes to identify homologs from other rice cultivars and from other plant species. As described above, Pi-CO39(t) nucleic acids are also used to advantage to produce large quantities of substantially pure Pi-CO39(t) proteins, or selected portions thereof.  
     [0079] Of greater significance, however, is the use of Pi-CO39(t) nucleic acidw to broaden the scope of resistance of rice cultivars and other plant species to a variety of  M. grisea  isolates, and even to plant pathogens other than  M. grisea.  For instance, in one embodiment of the invention, the Pi-CO39(t) coding region is operably linked to a heterologous promoter, preferably one that is either generally pathogen inducible (i.e. inducible upon challenge by a broad range of pathogens) or wound inducible. Such promoters include, but are not limited to:  
     [0080] a) promoters of genes encoding lipoxygenases (preferably from plants, most preferably from rice, e.g., Peng et al., J. Biol. Chem. 269: 3755-3761, 1994; Peng et al., Abstract presented at the general meeting of the International Program on Rice Biotechnology, Malacca, Malaysia, Sep. 15-19, 1997);  
     [0081] b) promoters of genes encoding peroxidases (preferably from plants, most preferably from rice, e.g., Chittoor et al., Mol. Plant-Microbe Interactions 10: 861-871, 1997);  
     [0082] c) promoters of genes encoding hydroxymethylglutaryl-CoA reductase (preferably from plants, most preferably from rice, e.g., Nelson et al., Plant Mol. Biol. 25: 401-412, 1994);  
     [0083] d) promoters of genes encoding phenylalanine ammonia lyase (preferably from rice; e.g., Lamb et al., Abstract of the general meeting of the International Program on Rice Biotechnology, Malacca, Malaysia, Sep. 15-19, 1997);  
     [0084] e) promoters of genes encoding glutathione-S-transferase (preferably from plants, most preferably from rice, or alternatively, the PRP1 promoter from potato);  
     [0085] f) promoters from pollen-specific genes, such as corn Zmg13, which has been show to be expressed in rice transgenic pollen carrying the corn gene (Aldemita et al., Abstract of the general meeting of the International Program on Rice Biotechnology, Malacca, Malaysia, Sept. 15-19, 1997);  
     [0086] g) promoters from genes encoding chitinases (preferably from plants, most preferably from rice; e.g., Zhu &amp; Lamb, Mol. Gen. Genet. 226: 289-296, 1991);  
     [0087] h) promoters from genes induced early (within 5 hours post-inoculation) in the interaction of  M. grisea  and rice (e.g., Bhargava &amp; Hamer, Abstract B-10, 8th International Congress Molecular Plant Microbe Interactions, Knoxville, Ten. July 14-19, 1996);  
     [0088] i) promoters from plant (preferably rice) viral genes, either contained on a bacterial plasmid or on a plant viral vector, as described by Hammond-Kosack et al., Mol. Plant-Microbe Interactions 8: 181-185 (1994);  
     [0089] j) promoters from genes involved in the plant (preferably rice) respiratory burst (e.g., Groom et al., Plant J. 10(3): 515-522, 1996); and  
     [0090] k) promoters from plant (preferably rice) anthocyanin pathway genes (e.g., Reddy, pp 341-352  in Rice Genetics III , supra; Reddy et al., Abstract of the general meeting of the International Program on Rice Biotechnology, Malacca, Malaysia, Sep. 15-19, 1997).  
     [0091] The chimeric gene is then used to transform the plant of interest. Upon wounding or challenge with a plant pathogen, the resulting transgenic plants would be induced to produce the Pi-CO39(t) gene product, thereby triggering the R gene defense response. In this embodiment, care must be taken to avoid using a promoter that is induced by necrosis, since use of such a promoter could result in a self-perpetuating hypersensitive response that may be lethal to the plant (see, e.g., Kim et al., Proc. Natl. Acad. Sci. USA 91: 10445-10449, 1994).  
     [0092] A preferred embodiment utilizes the Pi-CO39(t) gene controlled by its own regulatory sequences, rendering it either constitutively expressed or inducible by the product of the corresponding AVR1-CO39 avirulence gene that has been cloned. In this embodiment, the selected plant is transformed and a disease resistance response is generated by exposing the transformed plant to either or both of (1) the gene product of the AVR1-CO39 gene or (2) a suspension of non-pathogenic recombinant microorganisms (e.g., epiphytic or endophytic bacteria, or even a non-pathogenic stain of Magnaporthe) comprising the AVR1-CO39 gene. Upon pathogen attack, two levels of protection can occur in the transgenic plant: (1) the gene product produced by the recombinant epiphytes or endophytes triggers an interaction on the plant surface that prevents further penetration by the pathogen (e.g., the fungal conidia develop appresoria, but do not develop penetration pegs); or (2) the gene product produced by the recombinant epiphytes is carried into the plant tissue at the wound site, where it interacts with the corresponding R gene; product and induces an internal disease defense response. Thus, this pre-treatment confers resistance to Maganporthe isolates (and, presumably, other plant pathogens) which normally are virulent on those cultivars. These methods are described in detail in PCT US99/04047 and commonly-owned co-pending U.S. application Ser. No. 09/257,585.  
     [0093] In another embodiment, plants themselves can be co-transformed with Pi-CO39(t) and the fungal AVR1-CO39 gene. Co-expression of the genes results in an internal triggering mechanism to induce the resistance response.  
     [0094] It should be noted that constitutive production of the Pi-CO39(t) gene product may induce resistance without the aid of the AVR1-CO39 gene. Accordingly, it may not be necessary in all instances to use an inducible system.  
     [0095] 2. Pi-CO39(t) Proteins and Antibodies  
     [0096] Purified gene products of Pi-CO39(t), or fragments thereof, may be used to produce polyclonal or monoclonal antibodies, which also may serve as sensitive detection reagents for the presence and accumulation of Pi-CO39(t) polypeptides. Polyclonal or monoclonal antibodies immunologically specific for Pi-CO39(t) polypeptides may be used in a variety of assays designed to detect and quantitate the proteins. Such assays include, but are not limited to: (1) flow cytometric analysis; (2) immunochemical localization of expressed proteins in cells or tissues; and (3) immunoblot analysis (e.g., dot blot, Western blot) of extracts from various cells and tissues. Additionally, as described above, antibodies can be used for purification of Pi-CO39(t) polypeptides (e.g., affinity column purification, inmmunoprecipitation).  
     [0097] The following specific examples are provided to illustrate embodiments of the invention. They are not intended to limit the scope of the invention in any way. 
    
    
     EXAMPLE 1  
     Genetic Mapping of Locus Comprising Blast Resistance Genes Pi-CO39(t) in Rice Line CO39 and Identification of Large Insert Clones Linked to Resistance  
     [0098] Materials &amp; Methods  
     [0099] M. grisea  strains. Isolate ‘Guy 11’—virulent on CO39 and 51583—originally collected from a diseased rice plant in French Guyana, was provided by J L Notteghem (Institute de Recherches Agronomiques Tropicales Montpellier Cedex, France). Progeny 6082, avirulent on CO39 and virulent on 51583, was produced by crossing isolate 2539 and Guy 11 as described in Smith and Leong (1994). Guy 11 transformant (G11XF18-1(0) A#6), carrying aviruilence gene, AVR1-CO39 was produced by Farman and Leong (1998). Fungal cultures were stored at −20° C. in 6-mm chromatography paper discs (Whatman) as described by Valent et al. (1991).  
     [0100] Seed germination, inoculation procedure and disease severity rati˜gs. Seeds of rice genotypes CO39 and 51583 were procured from different sources as described in Smith and Leong (1994). Seeds were surface sterilized in 10% bleach and germinated on petri plates lined with moist blotting paper. Individual seedlings, usually 5-6 days after germination, were transplanted to disposable plastic square cubicles. The growth medium was Bacto professional planting mix (Michigan Peat Co., Housten, Tex.). Seedlings were flooded with water continuously. Seedlings were grown for 3-4 weeks in a growth chamber equipped with full spectrum white light GROW-LOX bulbs (230 μE/m/sec) set for 16 h photoperiods. Day/night temperatures were 28° C./21° C., respectively, and percent relative humidity was 33%. Plants were inoculated at the three leaf stage, 20-25 days after transplanting.  
     [0101] Inoculum was prepared by growing each isolate on oatmeal agar plates under full spectrum white light bulbs (Sylvania GRO-LOX 20W) (20-55 μE/m/sec) at 22° C. for 15-20 days. Spores were detached by gently rubbing the agar surface with a bent glass rod after adding 5 ml of 0.2% gelatin solution and sprayed on seedlings at a concentration of 10 4  spores/ml. Plants were placed in a plastic bag and tied from the top. Bags were removed after 24 hours.  
     [0102] Seven days after inoculation, ratings for disease severity were recorded on the youngest leaf that was expanded at the time of inoculation. We based our judgements on the ability of affected tissue to support conidiation under high humidity conditions and thus complete the disease cycle (Valent et al. 1991). To describe the interaction phenotype, a numerical system similar to that of Yu et al. (1987) has been adopted in this study: Type 0—no visible symptoms; Type 1—small dark brown, pin point-sized, non-sporulating lesions Type 2—dark brown, non-sporulating lesions 2-3 mm in length, Type 3—circular, sporulating lesions with the tan centers and dark brown margins; Type 4—large diamond-shaped, sporulating with tan centers and dark brown margins. Reaction phenotypes with lesion types 0, 1 and 2 were considered resistant while those producing reaction types 3 and 4 were considered susceptible.  
     [0103] Inheritance experiments. Reciprocal crosses between CO39 (resistant) and 51583 (susceptible) were made. Each F 1  seedling was tested for disease reaction and grown to maturity to produce a F 2  population. Individual plant progenies derived from a single F 2 plant constituted a single F 3  family. Segregation data were tested for Mendelian inheritance using the Chi-square method. Twelve homozygous resistant F 3  lines and six homozygous susceptible F 3  lines were selected for preliminary mapping using bulked segregant analysis. Equal amounts of DNA from each line were combined to make resistant and susceptible pools of DNA for bulked segregant analysis (Michelmore et al. 1991).  
     [0104] Microsatellite analysis. Microsatellite primer pairs for 20 loci on rice chromosomes 4, 6, 11 and 12 were synthesized using an ABI DNA synthesizer according to the manufacturers instructions. Total genomic DNA (75-100 ng) of CO39 and 51583 as well as of pools from 10 resistant or 6 susceptible F 3  progenies was used as template for PCR amplification by initial incubation at 92° C. for 5 min followed by 35 cycles of denaturation at 92° C. for 1 min; annealing at 55° C. for 1 min and extension at 72° C. for 2 min and a final 4 min extension at 72° C. Polymorphisms between the PCR products from DNA of parents and the resistant or susceptible F 3  progeny were analysed by electrophoresing the PCR products on 40-cm-long 4.5% denaturing polyacrylamide gels (PAGE) run for 1.5 h at 75 constant watts and silver stained according to the manufacturer&#39;s instructions (Promega). The polymorphic and co-segregating marker, RM202, was tested with DNA of a large number of individual F 2  progenies. The PCR products for the RM202 marker were resolved in 3.0% MetaPhor agarose (FMC Bioproducts) prepared in 0.5×TBE and run at 10.0 V/cm for 5 h.  
     [0105] Plant DNA extraction, restriction digestion, electrophoresis and Southern analysis. Plant DNA was prepared from fresh or frozen leaf tissue from individual plants according to the method of McCouch et al. (1988). Total genomic DNA of CO39 and 51583 was digested with several 6 bp restriction endonucleases to detect polymorphisms. The parental DNA as well as of individual F 2  progenies was digested with EcoR1, BamH1, EcoRV, Hind111, Dra1, Nae1 for mapping. Genomic and cDNA probes as well as microsatellite primer pair sequences from the high-density e Cornell maps (Causse et al. 1994; Chen et al. 1997) and the Japanese Rice Genome Program (Harushima et al. 1998) were selected. Electrophoresis and Southern hybridization analysis were done according to Farman &amp; Leong (1998). Hybridization methods were modified from Amasino (1986). The hybridization buffer was prepared according to the Amasino protocol, but without the PEG and NaCl and with reduced concentrations of NaHPO 4 : 0.125M NaHPO 4 , 7% SDS, 50% formamide, 1.0 mM EDTA, pH 7.2. High stringency conditions were used (42° C., 16 h). Post hybridization washes were: 2×SSC+0.1% SDS and in 0.1×SSC+1.0% SDS at 42° C. for 15 min each and in 0.1×SSC+0.1% SDS at 65° C. for 20 min, respectively. The final washing conditions were of greater stringency than were the hybridization conditions, giving a T m  of 68° C. Thus, greater than 95% homology would be required to maintain a hybrid. None of the post hybridization phosphate- containing buffers described in Amasino (1986) were employed.  
     [0106] Construction of Large insert DNA library. Indica rice variety CO39, which is a source of blast resistance locus in this study, was the plant material used for constructing a large insert DNA library.  
     [0107] The conventional binary cosmid vector pCLDO4541, designed for Agrobacterium-mediated plant transformation (Bent et al., 1994), was selected as a cloning vector. The vector has a cos site and a polylinker from pBluescript SK/KS which can facilitate cloning of foreign DNA at five restriction sites (Cal1, Hind111, EcoR1, BamH1 and Xba1). PCLDO4541 has been used for stable cloning and maintenance of large DNA inserts without any rearrangements (Tao and Zhang, 1998; Wu et al., 2000). The preparation of vector DNA, restriction digestion, and dephosphorylation were done according to Zhang et al. (1996).  
     [0108] Isolation of high molecular weight DNA, partial digestion and size selection. Rice seedlings were grown for 2-3 weeks, etiolated for 24-36 hrs under complete darkness and 25-30 g of fresh leaf tissue was used for nuclei isolation as per the “nuclei isolation method” described by Zhang et al (1995). Fresh leaf tissue (20 g) was ground into fine powder using a mortar and pestle in liquid nitrogen and immediately transferred into ice-cold homogenization buffer (HB: 10 mM trizma base, 80 mM KCl, 1 mM spermidine, 1 mM spermine, pH 9.4,0.5 M sucrose) plus 0.5% Triton®X-100 and 0.15% β-mercaptoethanol, mixed well and filtered through cheesecloth and Miracloth (Calbiochem-Novabiochem, La Jolla, Calif., USA) and centrifuged at 1800×g for 25 min. After washing in wash buffer the nuclear pellet was resuspended in 500 μl of HB and processed for microbead preparation according to Zhang et al. (1995). Nuclei were embedded in low melting agarose microbeads. The microbeads were incubated in lysis buffer (0.5 M EDTA, pH 9.0, 1% sodium lauryl sarcosine, 0.1 mg/ml proteinase K) at 55° C. for 36 h, followed by treatment with TE buffer (10 mM Tris-HCl, 1 mM EDTA, pH 8.0) plus 0.1 mM phenylmethylsulfonyl fluoride (PMSF) for I h, three times. The mirobeads were finally kept in TE buffer. Partial digestion of high molecular weight DNA with BamH1 was performed in the beads according to Zhang et al (1995).  
     [0109] Size fractionation of partially digested DNA in microbeads. Partially digested DNA was size selected using a modification of the method of Osoegawa et al. (1998). Microbeads containing the partially digested DNA were applied to the central well of a 1% low melting temperature agarose (SeaPlaque®GTG® agarose) gel and the lambda concatamer size markers in the flanking wells. The fractionation was done in BIORAD CHEF-DR®III sysytem. The DNA was separated in three different stages using a pulse direction of 120°. The first direction of the field allowed the DNA to migrate 1-1.5 cm from the $wells toward the top edge of the gel by electrophoresis at 5.0 V/cm for 6 h with a pulse time of 15 s. In the 2nd step, the CHEF running conditions were the same but current was reversed in order to bring all the fragments remaining in the gel back toward the wells. Small DNA fragments (≈50-100 kb) which moved beyond the wells were excised and discarded. Fresh 1% low melting agarose solution was poured into the excised portion of the gel. New marker DNA was loaded into the flanking wells not previously used. The high molecular weight DNA was then resolved at 6 V/cm for 16 h with an increasing pulse time of 0.1 s-to-40 s. Running buffer (0.5×TBE), CHEF chamber temperature (12° C.) and the angle (120°) were the same for all three steps. After electrophoresis, the flanking marker lanes along with peripheral portion of both the sides of high MW rice DNA lane were cut, stained with ethidium bromide, destained, washed in distilled water thoroughly, and aligned with the digested genomic DNA lane to mark the position of selected size ranges. Gel slices were cut at an interval of 0.5 cm to obtain gel slices containing DNA in the range of 150-500 kb.  
     [0110] Ligation, transformation, and storage of the library. Gel slices containing the size (200-300 kb) selected DNA were dialysed against TE buffer and the agarose digested with gelase (Epicentre Technologies, Madison, Wis.) as reported by Zhang et al. (1996). Insert DNA, which was BamH1 digested, was ligated to dephosphorylated vector DNA in 1:3 ratio at 16° C. overnight. The ligated DNA was transformed into Electromax DH10B  E. coli  cells (Gibco BRL, Grand Island, N.Y.) by electroporation using the Cell Porator and Voltage Booster system (Gibco BRL). The Cell Porator settings were the same as recommended by the manufacturer. Transformed cells were incubated at 37° C. for 1 h in 1 ml of SOC medium (2% Bacto typtopane, 0.5% Bacto Yeast Extrect, 10 mM NaCL, 2.5 mM KCL, 10 mMMgCl 2 , 10 mM MgSO 4  and 20 mM glucose, pH 7.0), and then plated on LB plates containing X-gal (80 μg/ml), IPTG(0.55 mM), and tetracycline (15 μg/l). The pates were incubated at 37° C. for 18-20 hrs for blue/white color development. The white colonies were picked with toothpicks and transferred to 384-well microtitre dishes containing 70 μl LB cell freezing medium (36 mM K 2 HPO 4 , 13.2 mM KH 2 PO 4 , 1.7 mM sodium citrate, 0.4 mM MgSO 4 , 6.8 mM (NH 4 ) 2 , 4.4% glycerol LB 25 g/l). The microtitre dishes were incubated at 37° C. for 24 h. The library was replicated and stored at −80° C.  
     [0111] Arraying of clones on high density filters. Large DNA insert clones were arrayed onto high density filters using a 384-pin Biomeck 2000 Robotics Workstation (Beckman, Fullerton, Calif). Each arrayed filter (7.5 cm×11 cm) contained duplicate copies of each clone&#39;s DNA in a 3×3 grid with no colony in the center (1,536 clones/filter). The library consisted of 23,040 clones arrayed on 15 filters. The filters were processed according to Zhang et al. (1996) and stored at 4° C. before probing.  
     [0112] Identification of clones linked to blast resistance locus (Pi-CO39(t)). The library was probed with a co-segregating RFLP marker RGA38 using the following conditions for probe preparation and hybridization.  
     [0113] BAC filter probing and hybridization. Probes were labelled using random hexamer Oligolabelling Kit (Pharmacia) except that 1 ng uncut lambda DNA was included along with the probe DNA and hybridized at 42° C. in 50% formamide, 7% SDS, 0.125 M Na 2 HPO 4  (pH7.2) and 1 mM Na EDTA overnight. The BAC filters were washed three times for 20 min each in 2×SSC+0.1% SDS at 42° C. for 1st wash and in 0.5×SSC+0.l% SDS and in 0.1×SSC+0.1% SDS at 65° C. for 2nd and 3rd washes, respectively. The filters were exposed to Phosphor screen and scanned after 30 min-1 h exposure using a Packard Cyclone Storage system. Overnight exposures were also scanned to see the background hybridization of all colonies caused by hybridization of lambda to the vector to facilitate the determination of the clone address. Mniprep DNA from recombinant BAC clones was isolated using a modification of alkaines lysis method described in Zhang et al. (1996). Large scale isolation of BAC DNA was done according to the QIAGEN® large-construct kit  
     [0114] Results  
     [0115] Genetic Analysis of resistance in CO39. Resistance phenotype of the F 1 , individual F 2  progenies, and F 3  families was consistently of reaction type 1 and the reaction phenotype of the susceptible seedlings was reaction type 4 in all segregating populations. All the reciprocal F 1  tested i.e. CO39×51583 or 51583×CO39 were resistant to  M. grisea  strain 6082, thereby, indicating that resistance is controlled by a dominant locus in the nuclear genome of CO39. Resistance to  M. grisea  progeny 6082 in three F 2  populations consisting of 604 F 2  progenies derived from different F 1  plants, segregated as a single dominant locus (Table 1).  
               TABLE 1                          Segregation f resistance in F 1  and F 2  generations of crosses between       indica lines CO39(R) and 51583(S)                                           M. grisea     No. Plants   Expected                                                 Cross   strain   R   S   ratio   x 2     P value                                                 F 1  (CO39X51583)   6082   5   0   all R   —   —       F 1  (CO39X51583)   Guy 11   0   4   all S   —   —       F 1  (51583XCO39   6082   4   0   all R   —   —       F 1  (51583XCO39)   Guy 11   0   3   all S   —   —       F 2  Family 1   6082   205   59   3:1   0.99   0.5-0.3       F 2  Family 2   6082   150   47   3:1   0.14   0.7-0.5       F 2  Family 3   6082   109   34   3:1   0.11   0.7-0.5       F 2  Family 4   Guy 11   180   55   3:1   0.32   0.7-0.5           (AVR           1-CO39)       Total F 2          644   195   3:1   1.38   0.3-0.2       Progenies                  
 
     [0116] Resistance to a Guy 11 (AVR1-CO39) transformant in one F 2  population consisting of 235 F 2  progenies also segregated as a single dominant locus (Table 1). Inheritance of resistance was also confirmed in F3 families derived from the F 2  populations used for mapping the resistance locus. Testing of 78 F 3  families against the Guy 11 (AVR1-CO39) transformant and 59 F 3  families to  M. grisea  progeny 6082 also showed that resistance is controlled by a single dominant locus. The segregation ratio of F 3  families was: all resistant: segregating for resistance: all susceptible and fit into 1:2:1 ratio (Table 2). The disease resistance locus in CO39 was designated as Pi-CO39(t).  
               TABLE 2                          Segregation of blast resistance in F 3  families of crosses between indica       rice lines CO39 and 51583                                 No. F 3       M. grisea                     Families   strain   R:Seg:S   1:2:1   P value               78   Guy11 (AVR1-   16:44:18   1.38   0.5-0.6           CO39)       59   6082   13:34:12   1.40   0.5-0.6                  
 
     [0117] Mapping of resistance gene(s) Pi-CO39(t). Microsatellite loci were randomly selected from four rice chromosomes 4, 6, 11 and 12 that were previously shown to carry many disease resistance genes (McCouch et al., 1994). Most of the test loci were found to be polymorphic between CO39 and 51583. Microsatellite locus, RM202, co-segregated in bulked segregant analysis of resistant and susceptible F 3  progenies. The resistance locus was fine mapped on chromosome 11 in two different F 2  populations consisting of 154 and 103 progenies, respectively. The program Mapmaker Version 2.0 (Lander et al., 1987) was used to determine association between molecular markers and the resistance locus using Kosambi Centimorgan function and LOD value of 3.0. The genetic map of resistance locus with respect to co-segregating markers is presented in FIG. 1. The resistance locus, Pi-CO39(t), was mapped between RZ141 (7.5 cM) and R2316 (3.0 cM) on one side (telomeric end) and RG211 (18.8 cM), RM202 (11.9 cM) and RG1094 (5.9 cM) on the centromeric end of the short arm of chromosome 11. Three markers, RGA8, RGA38 and G320 perfectly co-segregated with Pi-CO39(t) among all the F 2  progenies tested. RGA8 and RGA38 are resistance gene analogues mapped on chromosome 11 of rice (Mago et al., 1999). These three markers have been tested on 400 individual F 2  progenies. All the resistant F 2  progenies recombinant for different mapping markers were confirmed to be of the genotype RR or Rr. The frequency of recombination for different markers is given in Table 3.  
               TABLE 3                          Cross-over among markers:                             Marker   Number of Crossovers                                         RM202   43           RG1094   29           RZ141   39           RG211   62           R2316   15           RGA8   0           RGA38   0           G320   0                      
 
     [0118] C nstruction f a large DNA insert library f CO39. The large DNA insert library of the disease resistant genotype CO39 used in this study, was constructed from high molecular weight DNA isolated from nuclei in which more than 95% of the chloroplasts and mitochondria were removed during the preparation of nuclei. The DNA embedded in microbeads was partially digested with BamH1, size selected and ligated using a single size selection of 200-300 kb.  
     [0119] The library consists of 23,040 clones arrayed in 60 384-well microtitre dishes. About 65 random clones were selected, digested with Not 1 because Not1 cuts out the cloned insert DNA. The Not1 digested BAC DNAs were separated by pulse-field gel (PFG) electrophoresis (initial pulse time: 5 s; final pulse time: 15 s, 6 V/cm, 11° C., 120°, 15 h) to determine the sizes of the cloned fragments. A lambda concatemer ladder from New England Biolabs® inc. was used as a PFG marker. Insert size of recombinant clones ranged from 60-185 with an average insert size of 100 kb. All the 65 clones contained foreign DNA and one or more Not1 site within the insert DNA. This library represented about 5× rice genome equivalents with a theoretical probability of 95% coverage of each gene. Contamination of chloroplast DNA in the library was less than 1% as determined by probing with a fragment of the chloroplast gene, rbcL.  
     [0120] Identification of large insert clones linked to blast resistance locus, Pi-CO39(t). The library was screened with co-segregating probe RGA38 and three positive clones were identified. The identification of three clones hybridizing to RGA38 (corresponding to a single fragment on genomic DNA) is consistent with the number of clones expected from a 5× library of CO39. Restriction enzyme mapping, PCR and Southern analysis of positive clones, the genomic DNA of mapping rice parental genotypes, CO39 and 51583, was done to confirm that the clones are from the right location in the genome. Southern hybridization analysis of RGA38-positive clones digested with HindIII showed the presence of 7.5 kb fragment which was mapped in the resistant line CO39 and shown to co-segregate with Pi-CO39(t). Three RGA38 clones were extensively overlapping as shown by the HindIII restriction digestion fragment patterns. The largest clone, 36K6 (100 kb) was selected for shotgun sequencing. The CO39 library was probed with an amplicon derived from end sequence of a Nipponbare BAC clone OSJNBa91E20 which is part of contig 43 (see below) belonging to a syntenic region in the Nipponbare. Five positive clones in the CO39 library, including 36K6 and 4A14 which were positive to RGA 38, were identified. Ends of the largest clone from CO39, 5E2 (70 kb) were sequenced. Additional clones from the library are being identified to extend the contig. The CO39 library could not be screened with G320 because it is not detected by hybridization to the CO39 genome.  
     [0121] Screening of BAC library from Japonica rice variety, Nipponbare. Rice variety, Nipponbare is the model rice genome being sequenced by the International Rice Genome Sequencing Project Consortiun. Extensive resources are available for this genome project, including several large fragment libraries which have been end-sequenced and fingerprinted, a YAC physical map, and contig information obtained through overlapping fingerprinted clones. We screened a HindIII BAC library of Nipponbare consisting of 36,864 clones with an average insert size of 128.5 kb markers with the three markers co-segregating with Pi-CO39(t). Several positive clones were identified including five clones hybridizing to all the three co-segregating markers, RGA8, RGA38 &amp; G320. All the BAC clones hybridizing to three markers were in one fingerprint contig no. 43. All five of the positive clones were confirmed to contain the expected restriction fragments associated with the markers by restriction digestion and probing with marker clones as well as PCR to identify the expected amplicon associated with the markers. Contig 43 consists of 77 BAC clones. The tentative physical location of RGA8, RGA38 and G320 has been assigned by restriction and Southern hybridization analysis using a subset of representative BAC clones from contig 43. A minimum tiling path of three BAC clones was developed for sequencing (FIG. 1, lower panel). Information about contigs and BAC end sequences is available on the web site of Clemson University Genome Center (www.genome.clemson.edu). End sequences from the BAC clones in contig 43 were used to walk in the CO39 library. Nipponbare is susceptible to the  M. grisea  strain 6082 and Guy 11 (AVR1-CO39) transformant.  
     EXAMPLE 2  
     Sequence Information for Selected Segments of BAC Clones Containing Co-Segregating Markers  
     [0122] The following sequence information has been obtained in accordance with the present invention.  
     [0123] CO39.RGA8seq (SEQ ID NO:1): PCR product (360 bp) amplified from rice variety CO39 using primer sequences from the published RGA8 sequence. 84% identity to the published RGA8 sequence.  
     [0124] CO39.RGA38seq (SEQ ID NO:2): DNA fragment of 493 bp cloned from rice variety CO39 using primer sequences from the published RGA38 sequence. 97% identity to the published sequence.  
     [0125] RGA38 contig.26Nippon (SEQ ID NO:3): BAC clone 82N20 from susceptible rice variety Nipponbare being sequenced and one contiguous sequence (contig) of 15.6 kb contains RGA38 sequence from 13334-13834 with 97% nucleotide identity to published RGA38 and CO39 RGA38.  
     [0126] RGA8 contig.30Nipp (SEQ ID NO:4): BAC clone 82N20 from susceptible rice variety Nipponbare being sequenced and one contiguous sequence (contig) of 17.87 kb contains RGA8 sequence from 13334-13834 with 88% nucleotide identity to published RGA8 sequence and 97% identity to CO39RGA8 360 bp sequence.  
     [0127] A preliminary sequence analysis revealed resistance like gene in contig.491 from clone 36K6 (K6P36, SEQ ID NO:5). The CO39.RGA38seq is part of a RPR1-like gene in rice. RPR1 is a defense response gene induced by an agricultural chemical probenazole for protecting rice plants against pathogens, particularly  Magnaporthe grisea.  The RPR1 published gene maps at 1.0 cM from our co-segregating markers RGA8/RGA38/G320 toward the telomeric end of rice chromosome 11 and belongs to nucleotide binding site and leucine rich repeats (NBS-LRR) class of resistance genes (Sakamoto et al., 1999; Plant Mol. Biol. 40:847-855). The published RPR1 gene does not provide strain specific resistance. The RPR1-like gene in BAC clone 36K6 (from resistant rice CO39) is a single exon in contig.334CO39 from 5224-2501 (bottom strand) and has 62% identity at the amino acid level to the published RPR1 gene.  
     [0128] Another disease resistance like gene also appears in contig.491 from clone 36K6 (SEQ ID NO:5). The gene is like the Xa-1 gene and has 42/o identity at the amino acid level. The Xa-1 gene has been cloned in rice and confers a high level of specific resistance to a Japanese race 1 of the bacterial pathogen,  Xanthomonas oryzae  pv.  oryzae.  It also belongs to NBS-LRR class of resistance genes and maps to rice chromosome 4 (Yoshimura et al., 1998 PNAS 95: 1663-1668)  
     EXAMPLE 3  
     Comparative DNA Sequence Analysis of Resistant and Susceptible Cultivars at the Pi-CO39(t) Locus  
     [0129] The relationship between the genetic map and the physical maps of the region of rice chromosome 11 associated with Pi-CO39(t) in Japonica variety Nipponbare and Indica variety CO39 is shown diagrammatically in FIG. 1. The preliminary sequence assembly of two BAC clones to give ordered contigs is shown diagrammatically in FIG. 2. Comparative sequence analysis of blast resistant (CO39 indica) and susceptible (Nipponbare japonica) rice cultivars at genomic regions co-segregating with Pi-CO39(t) showed that these two haplotypes are substantially diverged with respect to the relative number, size, orientation and location of resistance gene homologs within each cluster (FIG. 2). Gene prediction using GENSCAN, GeneMark.Arabidopsis and BLASTX indicated the presence of several disease resistance (NBS-LRR)-like genes with highest similarity to RPR1, Xa1 and Pi-ta. RPR1 (rice probenazole-responsive) is involved in induced resistance to blast in rice (Sakamoto et al., 1999); Xa1 confers a high level of resistance in rice to race 1 of bacterial blight ( Xanthomonas oryzae  pv.  oryzae ) in Japan (Yoshimura et al., 1998); Pi-ta is a rice blast resistance gene (Bryan et al., 2000. Plant Cell. 12: 2033-2045). All the three genes belong to non-TIR NBS-LRR subfamily of plant disease resistance genes suggested to be more abundant in monocot genomes (Meyers et al., 1999). Lack of significant synteny between the Nipponbare and CO39 haplotypes indicates a dynamic nature of these gene clusters with the potential to adapt rapidly to novel pathogen variants.  
     EXAMPLE 4  
     Detailed Sequence Analysis of BAC Inserts K6P36 and E2P5 from Indica Variety CO39 Large Insert Library  
     [0130] The complete sequences of BAC K6P36 (also referred to herein as 36K6) and E2P5 (also referred to herein as 5E2) are set forth herein as SEQ ID NO:5 and SEQ ID NO:6, respectively.  
     [0131] Genetic/Physical Mapping  
     [0132] Four microsatellites (di-, tri-, and hexa-nucleotide repeats) were identified in the 90 kb sequence of K6P36. Primers were designed from the flanking 100-110 bp unique sequence and amplified on genomic DNA of mapping parents (CO39/51583) as well as segregating progenies. Two microsatellites were monomorphic between CO39 and 51583, whereas other two were null for 51583 (no amplification).  
     [0133] Primers were designed from predicted genes in K6P36 sequence for fine mapping. About 250 homozygous susceptible F2 progenies have been tested with RFLP marker G320, microsatellites, gene specific primers, E2P5 clone end sequence to detect any recombination within KP636. The physical position of fine mapping markers in the K6P36 sequence is shown in Table 4.  
               TABLE 4                          Physical Position of Markers in 36K6 Sequence                                 Position       Marker   Size (Kb)   (kb from centromere-proximal end)                                 36K6RPR1   4.1    8.1-12.0       36K6RPR1rg38   3.6   38.0-41.0       36K6Xa1Ex4   4.2   47.0-51.2       36K6Xa1(2.6)   2.6   51.5-54.1       36K6Xa1Ex1   0.6   52.8-53.5       M22/8 (Microsat)   0.24   55.0-56.0       M10L/R (Microsat)   0.2   78.0-79.0       36K6PitaEx2   1.9   83.6-85.6       36K6PitaEx1   0.7   85.7-86.5       36K6Pita   2.3   85.6-88.0       E2P5 End   0.48   E2P5 End Seq.                  
 
     [0134] End sequence of Nippon BAC clone, 24M23 overlapping with the 44D15 end sequence has been mapped at 0.5 cM from Pi-CO39(t), as shown in FIG. 1.  
     [0135] Annotation of CO39 Clone K6P36  
     [0136] Sequence (90 kb) of K6P36 clone co-segregating with the disease resistance gene(s) Pi-CO39(t) in CO39 has been annotated using three gene prediction programs, Genescan.arabidopsis, GeneMark.arabidopsis, and GeneMark.rice. Comparative analysis of three programs with respect to gene length and similarity to published disease resistance genes indicated that GeneMark.arab followed by Genescan.arab are better than GeneMark.rice probably due to the fact that former two programs are better trained for predicting disease resistance-like genes (Table 5).  
               TABLE 5                          Gene Predictions for K6P36 Sequence (90 Kb)                                     RPR1-like   RPR1rg38   Xa1-like   Pita-like                                                 GeneScan.Arab   Length   17409-7047   38580-41303   52897-44286   85741-69018           Exons   8   1   6   16       GeneMark.Arab   Length   10896-7881   38580-41303   53552-47154   87376-83281           Exons   2   1   5    7       GeneMark.Rice   Length   10896-7881   38580-41303   53552-47224   Not identified           Exons   5   4   6   Not identified                  
 
     [0137] A number of disease resistance genes have been cloned in Arabidopsis compared to rice. Four disease resistance-like genes were identified in K6P36 (Table 6). The annotation of RML1- is referred to as a Pi-ta-like gene (37% similarity). Pi-ta is a rice blast resistance gene in rice (Bryan et al., 2000, supra). All the four predicted resistance-like genes have signature conserved motifs present in the NBS-LRR class of disease resistance genes. A non-TIR sub-domain, so far found only in monocot NBS-LRR genes, is also present in the four predicted genes. Hydropathy analysis of all four genes showed that these are most likely cytoplasmic, soluble proteins. All have LRR domains, however the Pi-ta-like gene has a rudimentary LRR domain like the Pi-ta gene itself.  
               TABLE 6                          Domain, Subdomain Predictions for K6P36 Genes                                                                 RNBS-D   LRR   Hydro-           P-loop   Kinase-2a   Kinase-3a   GLPL   (Non-TIR)   Domain   pathy               Consensus   GVGKTT   LVVLDDWW   GSRIIITTRD   CGGLPLA   CFLYCALFPED               RPR1-Pub   GMGGLGKT   ENFLIVLDDV   NFQASRIIITTRQGDV   CQGLPLAIVSIGG   LRNCFLYCSL   LRR   Soluble       RPR1-like   GGLGKTT   SCLIVLDDVWD   PQASRIIITTR   CKGLPLALV   QKNCFLYCSL   LRR   Soluble       RPR1-rg38   GGLGKTT   KCLIVLDDVWD   NFQATRVIITTR   CHGLPLAIV   RNCFLYCSL   LRR   Soluble       Xa1   GNGGIGKTT   KKFLIVLDDV   GNMIILTTRIOS   LKGNPLAAKTVGS   LOOCVSYCSLFPK   LRR   Soluble       Xa1-like   GIAGVGKT   RTKKFLLVLDDVW   GNMILVTTR   NGNPLAAE   LQQCFLYCS   LRR   Soluble       Pita   GSGGVGKTT   RYPIIIEDLW   NNSCSRILTTEIEPV   KCGGLPLAITIT   CLKACLLYLS   Rudimentary   Soluble                               LRR       Pita-like   GAEGIGKT   RYFIVDDLWA   GSRIITITKVDE   KCGGSPLA   CLKTCLLYLS   Rudimentary   Soluble                               LRR       Pib   GMGGLGKTT   KSCLIVLDD   TSRIIVTTRKENI   CDGLPLAIVVIGG   LKSCFLYL   LRR   Soluble                                          
 
     [0138] Analysis of Predicted Resistance-Like Genes in Rice Varieties  
     [0139] Popular rice varieties, Crocoderi (R), Cypress (R), Drew (R), M202 (S), IR64, Nipponbare (S), and Azucena (R) were characterized for resistance (R) or susceptibility (S) and tested for the presence/absence of predicted genes by PCR as well as genomic DNA hybridization to find any functional correlations. Two genes, Xa1-like and Pita-like, did not show any correlation, whereas RPL1 and RPL6 showed correlation for the presence of a common hybridizing fragment in susceptible genotypes. Pedigree lines of resistant variety CO39 are being tested for disease reaction and also for the presence/absence of predicted R genes to infer any correlation as well as trace the origin of the functional allele.  
     [0140] Analysis of clone E2P5 Together with Clone K6P36  
     [0141] Table 5 above lists genes predicted in the sequence of CO39 clone K6P36. Sequence analysis of clone E2P5 also predicts genes located in this clone. These are shown in Table 7 below, together with the predicted genes in clone K6P36. The predicted genes are shown diagrammatically in FIG. 2.  
               TABLE 7                          Genes Predicted in the Sequence of CO39 Clones K6P36 and E2P5                                         %       Clone   Gene   Similarity to   Similarity               K6P36,   CODRL1   Rice blast resistance gene RPR1   70       E2P5   (RPR1-like)       K6P36   CODRL2   Rice blast resistance gene RPR1   74           (RPR1-rg38)       K6P36   CODRL3   Rice bacterial blight resistance   52           (Xa-like)   gene Xa1       K6P3   CODRL4   Rice blast resistance gene Pi-ta   52           (Pita-like)       E2P5   RSL1 (CSL1)   Barley serpin gene   51       E2P5   RSL2 (CSL2)   Barley z-type serpin gene   55       E2P5   RSL3 (CSL3)   Wheat serpin gene   52                                  
 
     [0142] An alignment of the genomic region of CO39 included in BAC clones K6P36 and E2P5 with the corresponding area of the Nipponbare genome is shown in FIG. 3. Table 8 below provides a summary of the sequences of all polynucleotides disclosed herein, including sequences comprising the open reading frames identified in these segments of both the CO39 and Nipponbare varieties.  
               TABLE 8                          Summary of sequences and SEQ ID Numbers for GenomeFragments       and Open Reading Frames of Rice Varieties CO39 and Nipponbare                     SEQ ID NO:   Genome Fragment or ORF                             1   CO39.RGA8seq; PCR product amplified from CO39 using           primer sequences from published RGA8 sequence       2   CO39.RGA38seq; DNA fragment cloned from CO39 using           primer sequences from published RGA38 sequence       3   RGA38 contig.26Nippon; portion of BAC clone 82N20           from Nipponbare, containing RGA38 sequence as well as           ORFs NBRS and NBR6       4   RGA8 contig.30Nippon; portion of BAC clone 82N20 from           Nipponbare, containing RGA8 sequence and ORF NBR7       5   BAC clone K6P36 from rice variety CO39       6   BAC clone E2P5 from rice variety CO39       7   CODR1 ORF from CO39       8   CODR2 ORF from CO39       9   CODR3 ORF from CO39       10   CODR4 ORF from CO39       11   COSL1 ORF from CO39       12   COSL2 ORF from CO39       13   COSL3 ORF from CO39       14   GTPase ORF from CO39                  
 
     [0143] References  
     [0144] Amasino R 1986. Acceleration of nucleic acid hybridization rate by polyethylene glycol. Anal. Biochem. 152:304-307  
     [0145] Bent A E, B N Kunkel, D Dahlbeck, K L Brown, S R Schnidt, J Giraudat, J Leung and B Staskawicz 1994. RPS2 of  Arabidopsis thaliana:  A leucine-rich repeat class of plant disease resistance genes. Science 265: 1856-1860.  
     [0146] Bryan G T, K S Wu, L Farrall, Y Jia, H P Hershey, S A McAdams, K N Faulk, G K Donaldson, R Tarchini and B Valent 2000. tA single amino acid difference distinguishes resistant and susceptible alleles of the rice blast resistance gene Pi-ta. Plant Cell 12: 2033-2045.  
     [0147] Causse M, T M Fulton, Y G Cho, S N Ahn, K Wu, J Xio, J Chunwongse, Z Yu, P C Ronald, S B Harrington, G A Second, S R McCouch and S D Tanksley 1994. Saturated molecular map of the rice genome on an interspecific backcross population. Genetics 138:1251-1274.  
     [0148] Chen X, S Temnykh, Y Xu, Y G Cho and S R McCouch 1997. Development of a microsatellite framework map providing genome-wide coverage in rice ( Oryza sativa  L.) Theor. Appl. Genet. 95: 553-567.  
     [0149] Farman M L and S A Leong 1998. Chromosome walking to the AVR1-CO39 avirulence gene of  Magnaporthe grisea:  discrepancy between the physical and genetic maps. Genetics 150: 1049-1058.  
     [0150] Grant M. R Godiard L Straube E Ashfield,T Lewald, J. Sattler A Innes R W and Dangl,J. L 1995. Structure of the Arabidopsis RPM1 gene enabling dual specificity disease resistance. Science 269 (5225), 843-846.  
     [0151] Harushima Y, M Yano, A Shomura, M Sato, T Shimano, Y Kuboki, T Yamamoto, S Y Lin, B A Antonio, A Parco, H Kajiya, N huang, K Yamamoto, Y Nagamura, N Kurata, G S Khush and T Sasaki 1998. A high-density rice genetic linkage map with 2275 markers using a single F2 population Genetics 148:479-494.  
     [0152] Kiyosawa S 1981. Gene analysis for blast resistance. Oryza 18: 196-203  
     [0153] Lander E S, P Green, J Abrahamson, A Barlow, M J Daly, S E Lincoln and L Newburg 1987. MAPMAKER: an interactive computer package for constructing genetic linkage maps of experimental and natural populations. Genomics 1: 174-181  
     [0154] Mago R, S Nair and M Mohan 1999. Resistance gene analogues from rice: cloning, sequencing and mapping. Theor. Appl. Genet. 99: 50-57.  
     [0155] McCouch S R, G Kockert, Z H Yu, Z Y Wang, G S Khush, W R Caffman and S D Tanksley 1988. Molecular mapping of rice chromosomes. Theor. Appl. Genet 76:815-829.  
     [0156] McCouch S R, R J Nelson, J Tohme and R S Zeigler 1994. Mapping of blast resistance genes in rice., pp 167-186 in  Rice Blast Disease  edited by R S Zeigler, S A Leong and P S Teng. CAB International, Wallingford, UIK (in association with the International Rice Research Institute, Philippines).  
     [0157] Meyers B C Dickerman A W Michelmore R W Sivaramakrishman S Sobral B W and Young N D 1999 Plant disease resistance genes encode members of an ancient and diverse protein family within the nucleotide-binding superfamily. Plant J. 20:317-332.  
     [0158] Michelmore R, I Paran, and R Kesseli 1991. Identification of markers linked to disease resistance genes by bulked segregant analysis: a rapid method to detect markers in specific genomic regions by using segregating populations. Proc. Natl. Acad. Sci. USA 88:2236-2240.  
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     [0160] Sakamoto K Tada Y Yokozeki Y Akagi H Hayashi N Fujimura T and Ichikawa N 1999 Chemical induction of disease resistance in rice is correlated with the expression of a gene encoding a nucleotide binding site and leucine-rich repeats. Plant Mol. Biol. 40:847-855.  
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     [0162] Tao Q and H B Zhang. 1998. Cloning and stable maintenance of DNA fragments over 300 kb in  Escherichia coli  with conventional plasmid-based vectors. Nucleic Acids Res. 26:4901-4909.  
     [0163] Valent B, L Farrall &amp; F G Chumley 1991.  Magnaporthe grisea  genes for pathogenicity and virulence identified through a series of backcrosses. Genetics 127: 87-101.  
     [0164] Wu Y, L Tulsieram, Q Tao, H B Zhang and S J Rothstein 2000. A binary vector-based large insert library of  Brassica napus  and identification of clones linked to a fertility restorer locus of Ogura cytoplasmic male sterility (CMS). Genome 43: 102-109.  
     [0165] Yoshimura S Yamanouchi,U KatayoseY TokiS WangZ X Kono I Kurata N Yano M. Iwata N. and Sasaki,T 1998 Expression of Xa1, a bacterial blight-resistance gene in rice, is induced by bacterial inoculation. Proc. Natl. Acad. Sci. U.SA. 95 (4):1663-1668.  
     [0166] Yu Z H, D J Mackill, J M Bonman, S R McCouch, E Guiderdoni, J L Notteghem, and S D Tanksley 1996. Molecular mapping of genes for resistance to blast ( Pyricularia grisea  Sacc.). Theor. Appl. Genet. 93: 859-863  
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     [0169] While certain of the preferred embodiments of the present invention have been described and specifically exemplified above, it is not intended that the invention be limited to such embodiments. Various modifications may be made thereto without departing from the scope and spirit of the present invention, as set forth in the following claims.  
    
     
       
         1 
         
           
             14  
           
           
             1  
             358  
             DNA  
             Oryza sativa  
           
            1 

agacgacact ggtcacaaat gtgtatgaac gtgaaaagat caacttctct gctcatgcat     60 

ggatggttgt gtctcaaacc tacactgtgg atgctctatt aaggaagctg cttaggaaag    120 

ttggttacac agaaccacca ctgtcaagta acattgacaa aatggatgtg tatgatttga    180 

aagaggaaat aaagcgatgc tcaaagttag aaaatgcttg atcgtacttg atgatgtctg    240 

ggatcaagaa gcatactttc aaatacgtga tgcattccag aatgaccaag gaagtcgcgt    300 

aataatcaca acacggaaga atcatgtggc agctcttgct tcctcaacat gtccttaa      358 

 
           
             2  
             493  
             DNA  
             Oryza sativa  
             
               misc_feature  
               (123)..(123)  
               N is any nucleotide  
             
           
            2 

ggtggggaag acgacattag tcacaaatat ttatgagcgt gaaaaggtca actttgctgc     60 

tcatgcatgg attgttgtct cccagaccta caatgtggag gctctattaa gaaagctcct    120 

tanaaagatt gggtctactg aactgtcact tgatagctng aacaatatgg atgcacatga    180 

cctgaaagaa gaaattaaga aaaagattga agatagcaaa tgtttgattg tgctggatga    240 

tgtctgggac aaaaaagtgt actttcagat gcaagaagca tnccagaatc ttcaagcaac    300 

tcgagtcntc atcacaactt agagaatgat gttgcagccc ttgctacctc agcacgccgc    360 

tnaacctcca gcctttgaat ggcgctgatg catttgaact ctctgtagaa gggctttcta    420 

taacaagggc cacaaatgcc ccaaggagct agagaaggtt gctaattcta tagtggatag    480 

gtgcatggcc ttc                                                       493 

 
           
             3  
             15686  
             DNA  
             Oryza sativa  
           
            3 

ttcccccccc ccccccccag aactagattg cacacccagt gcatgtgaga accccttgga     60 

gtataaaagg aggttcatgt ccagtaagtg ggagagagga caatttggag taggaactcc    120 

tagctctggc ttgtacatca gagattcaga gacttcaaaa gcttagaaaa atcatcacac    180 

agaagagtag ggtattacgc tccttagcgg ccagaacttg tataatccct tttgtctccc    240 

ccttttgatt gagggcccaa ccccctcggt ccttttcgat cttatcagtt tcttgattta    300 

cacacgctgt cccccgccga actaacgaag gaggggcctc aaggtccccc gcttgaggag    360 

tttatccccc gacagttatc tttacatcag acttccaacc gatgtatact ttaaccgtcg    420 

agcctacatt taatattttg catcaatatc gatcgattgg ctcattggac atctacttca    480 

tcatattatc atcaagttga ttggattgtt tattcaagtt cttccattat ctttatctaa    540 

gtgtcagaat ctacattgga tatatagcag attgttcaaa accttatcga catatgctag    600 

tatcgttaca tcggcttttt ggcctatcgg ttctttatca tcaattatct atgttgtcag    660 

ttatagaatc aaactgactg acacgcccgc actggagtta agcaaatttc tcaggccctt    720 

gtgtgtcacg acgaattttc acatcaactg cttgatatca taacgagcca gactaagccg    780 

agctgagcca gcttggcatc caccttgagt tacagtgtgt agcttagtat actcaagtta    840 

tatttgtttc ccagatcaag ctagcacaca aagtaaacat gataactaca tcacgatcac    900 

gattttatta ataaataata aacaaatagt ataaatttta gttgtgactt atgaccaggt    960 

tttataattt tactagaaat atcgttagtg tgtcgtggat gccctgcgca ttgtaatata   1020 

gcacgatccg attaatctct acttttgggc ttgatctggt ttttgcgaac aaatttacaa   1080 

agaaattgaa aaaaaaaaag caggtattga gaatgagatc ggggacctct tggcttatgc   1140 

agagaccatg agttttctga atggttctat taacttgatg ctcctccgca accataagat   1200 

ttcgcatcta attttgatta tctgtcttat ttaatttttt ttaattagta tttttattat   1260 

tatgagatat aaaacatgaa tagtacatgt aacttatgtt tttaattttt tttatttttt   1320 

taaataaaac ggatgatcag agttgtgcac ggaaaattat gaatgaactt acagatagaa   1380 

ttatagggag tggttaatat aatcgttttg acattaatga aagcttcctt tatactaaaa   1440 

ggaaaaaaaa cgagtcaacc ccgatgcaca aggggatcga ataggaggat aagcccgtcg   1500 

agtagccaga aatcgcagat ggaggcagct attttgagcg gtttgttgaa aatactcgcg   1560 

tcgaggatgc tctctctggt agatcagaag tacaatctgt acaagggatt caaaggcgac   1620 

gcagaatttc tgttgaagga gctccgcatg atcgccggag ccattgacga gcagctcttg   1680 

cggacggtga gccgtggaag cgtgctgctg ctgtccatcg aagagcttcg cgacctggct   1740 

cgcgacatag aggactgcgt agatcgcatc atgtatcaga aaactcggga tcagcaagct   1800 

tctcttttca gtatcaattc cgtcacggga acgtcgaagc ttcagttggc caaagagatg   1860 

aagaagctga ggaagagagc agacgaagcg aaagagcggc gagaaagata cacggtggtc   1920 

gtcggtcatc agtcctcccc tgtcagctcg gatgagcaac gctgctccgg tgcatctgac   1980 

gggagaaacc tccaggctga tctcgtcggc atcgacctgc cccgagaaga acttctggag   2040 

catctgaaag aagccgagcc gaagaagctt aaggtgatat cgattgttgg gttctgcggc   2100 

ttggggaaga ctgcacttgc aagggagttg tacaacaaca gcggtctcgg ccggagtttc   2160 

agtaaacagg cctgggtttc tgcggcacat ggtgatccga gcaaggtgtt gagggagata   2220 

atcggacaac tggtatctaa cccgccatcg gatgcctccg ttgtcgacct ggaccagctt   2280 

attgtaaatc tcactgatca gctgaccaac ttgaggtatc aacaattctt cttctaatta   2340 

ggctgattta agttccacat gctctgctcc attttttcat acccgtgatt cgatttatgt   2400 

ttcccttatg gagaaatttt atagtcctta agaaagtaac tgaagatact aagattttac   2460 

actaaaattt ttggtatttc aaggtaccaa attttacact agaaaaatat gatacctcct   2520 

ggtattttct caaggattgt aaaattaccc ttcccttatg ctattcaggt ttcttcagat   2580 

tgttgatatg ctttagagtg gttatagaga gcagagtttc tttttatgtt ttttagaaac   2640 

tacagtactg taatactgct gcctaccttg gacggtatag tgttatcacc ttcacaatat   2700 

ctccaactat gatggagata tatcatgatg tatgaagata tatatgtcca gtcctcagtc   2760 

ctatatccgt ctctgtctcc ctctcaagaa agcaggtggc taggcttatg gtagctgtgc   2820 

tgaggtgagg taatggttgt atagccgtat cacgatggta ttatcgagtt tcagggtgct   2880 

atcatagaga tagcatcatg ctcgtttata gaggtattat tgcgttttac attgctatca   2940 

tggtacattg gttttatcac catataacct gatattgtga tactacagtg tgtcatataa   3000 

ctccactccg gtgtgtcatg gtaacttggc tttcagttct agatttggaa ctctctactt   3060 

ttctgtgtgt ttagttgatt acagtgtaat agcggtgtat agtttccatg agttatatac   3120 

tcatgttatc ttccaaacaa acaacaaact atagactatg cagacaacta aattaacgca   3180 

gtaaaataat tcagtgtgag gcctacggat tggacaatta cagtacagtg aaaacagagg   3240 

ctgtgcttgc ttggcccatg gttgttattt gttcatacgg agtggatttt tactaatgtc   3300 

cattcccttt tgttgtttca tgttattagg tatttcattg taatagatga catgcgaaaa   3360 

gatttgtgga gtactattga atctgccttc ccgaaggatg gtttcagcag tagaatagtg   3420 

gtgaccacaa cagtgcaatc agtagctaaa gcctgcagtt cagccaatgg ctatgtatat   3480 

aaaattagaa ggctagataa gatacactca aaaaaattgt tcttgaagaa tgcttgtccg   3540 

gtggaatatc aagattacat tcagcctgat tcagtacgga ttttgaagaa atgtgatggt   3600 

caagcactcg cccttcttac agtaggtcaa ttcttgcgaa aaatgggctg gccaagagaa   3660 

cccaagtgtg aagatgcttg caaccagcta tgcaatcatc tggaggatga cgacaccttg   3720 

gagagaatgc gacaggtgct gattcatgag tactctacac tatcttgcca tgctctcaaa   3780 

gcctgcttgc tatattttgg catgttcccc agtggtcatt caatcaggag aaaaagacta   3840 

ctcaggcgat ggtcagctga aggatttgta gaagcactac cttcaggttc ttttcctgat   3900 

ccagcagttg agaatttcaa taagctcatg gacagaaata tcattcaacc cattgatcta   3960 

agcagcaacg aggaggtgaa gacatgtcaa acttatggca tgatgcgcga gttcattttg   4020 

ctcaaatcta tttctcagga ttttattgct gtctttggtg acaagaagct ccaataccaa   4080 

catgtccgtc gcctttgtct ccaaaacaat agtgctgtag atagcagcaa tcttgacatc   4140 

gatttgactc ttgtccgatc tctggtagtc tttgggaaag caggtaaagc tattttggat   4200 

ttcaagaagt atcaactgct tcgagtctta gatcttgaag aatgtactga cttggacgat   4260 

gatcatctca ttcaagtgtg caaccttttt cttctaagat atttgagcct tgggggcaaa   4320 

gtcaccaaac ttccagaaga gataactaaa ctgaaacttt tggagacact tgatcttagg   4380 

agaagaaagg aggtgactat caacctgtca acagaagtca tcaagctacc atatttaatt   4440 

aatctgcttg gaaagtttaa gctcctaaat aaagccaaga gattgaacga actgcagaag   4500 

tttttgtccg aaaactgtag attgcagaca ctagcaggat ttagcacaga cggaagtgaa   4560 

ggatttccag aacttatggg ccacatgaag caattgagaa aggtgaaagt ttggtgtact   4620 

gaactatcag caagtagttc tgggtttact aatcttcaaa atgccattca aaaatttata   4680 

catgacgaac agaatggatt caacgatcct cgctctttgt cgcttaactt tgataattgc   4740 

cctgaagact tcctctacga gataaaagcc ccatgctacc ttcgatcgtt gaaattacat   4800 

gctaaattac tggaatcgcc caaatttgtg gtactattgc gtggcctcca ggagttgtgc   4860 

atttcatcat cagctacaaa attgaccaca ggtcttcttt cagctttgag taacctgagg   4920 

aaattgaagt atctcaagct gattgcagat caacttgagg agttcattat taaggataat   4980 

gcattgccaa gcctgctaag cctatgtttt gtgctgaacc gtcctacatt cccggtaatc   5040 

aaaggaaatg ctttgaggtt tctcaaatca ctccagcttc tctgtaaaaa tctagttggc   5100 

ctttcagaga tcaacattaa ttgtctcaaa cgccttgagg aagtcgttct tcatccatgt   5160 

gtgaacaaag caactaaagt tacatgggaa agggcagcta aggaacatcc caataggcca   5220 

aaagttttgg tgcttgaaaa ggttgatcta gcagatggcc atgaagaaga ttcagattcg   5280 

accccaactg aaattgtgac aaataaggaa tctactgttg caggaaatgg agcagatatt   5340 

gacaaacaga actatattga caaacagaac tatcctacca gtaatatgtc acgtgcaatg   5400 

gtttcccctg ctttgactga gccatgcagc gctgggaatg gtgtggagtc ctcttgtgcc   5460 

tgacgacacg gtcagttttg tggaataatt cccttctctg ttcttattgc aacaaagtga   5520 

aacaaaattt gcgaaagaat tctactgaat tgaatatgga ataaatttgc aaaaaaaatt   5580 

cttctttatt aaatctgtac agtatttttt tctgtaaagt tcaagtttac aggttatcaa   5640 

aagataaaag taagaaaatt ttggacaaca atacaaatgg atttgtattc cccaaaattt   5700 

caagtgctta tatttgttag tttccatcaa tcagcacttt aggctgactc tatgtttcca   5760 

acttgacata ttcatgctat cgtaattgga acctacaaat ttgatacgcc ttctgatttc   5820 

aaatataatt tgtttttgat gagcacatga atagaaaatt tatcttcaaa ttactttgtt   5880 

acatctattt atactagatc ggaaaatatg ccatctcttt gagagtgata ggatttattt   5940 

tatttggtgt ggctaaatat ggaagaaaaa ggatgaaaaa gtgtccatgt tataaaatta   6000 

cttagtaaag atttttttac ttagtaaaga gttgagagtg ctaaaacaac ttgtatttac   6060 

attagaaatc agaaagagta ataatctagt tagttgcagt ttctttaaac caatagttgc   6120 

atttacgatc aactgaaatt aatcttgcca tgtaaattgc aagctgctta tgctgtcgct   6180 

gatgattaat ccgtatggct tctgttttct tttattttta aacaaatgct tagccggatt   6240 

atgtgtatgt gtaccttttt ctttatattt ctctatccaa ttttgtccaa tactgctaca   6300 

gttgggcctt gctttagtac tcctcccagg aaaaacttag cagatcttac agctcctaag   6360 

aaaaggtttt cgcacccata tcccaactga acaccaacgc gctatttgca tctaaagttg   6420 

taagcatttc atgtcttaga agtagttgga cgactcagcc accaacctag cattgatgac   6480 

tagaaaacag ctttgacctt aagtagctac tagttcaaat cttttgtttt ttcaaaacct   6540 

gttttcatgc tcagtttggc tcttctttct caagagaaat aaccctgttt ctatatcagt   6600 

gactataaaa atcagggttt gtgtgaatac aaagcggtta gaaaacatat tggaggagtg   6660 

gttttgcagt gctcttactc tctaactgat caactgtgaa actttgttca ttgagatctt   6720 

ttacagtact tggaaggtac ctccttaacc aattgatacc catcattaat tcattttttt   6780 

cgataacttc taactgggct cactcctggc ctctgcatga aatgcacaca gctacaaaac   6840 

aggatctaac tagactctca acacaaaact aagaaattag tgactatcaa gccgaagact   6900 

agatcgccac ccatgctcta gggtaaaaaa ctcatgtacc acctgatcca aacaacgcga   6960 

taccaccaca atacctgaag acccggtttg tggaggatag acctggtgcg tagccacctg   7020 

gtgactaaag caataacctg caaaggagaa gataccatct tattatcaaa aattgccccg   7080 

tttcagctta gccaaatgga ccaacaaata gctgttgcac ccatcaaaag cagatttctc   7140 

atatccttag gaacacatgt aaaccaacgc ccaaacatat gattaaaatt ttgaggatgt   7200 

tgtaagttat aagccatatg aatcacggat caaaccaaac gagtaacatg acattggaag   7260 

aacaaatgtt ggatggtttc gtccttatga cagaagcaac gtttcttatt acctttccac   7320 

tttcgcttag ctagattatc cttggttaga attatgcccc gacgtaagta ccaaaagaaa   7380 

atctttactt tgagcaatac ttttaccttc caaatacatc tatttatatt cgggatgccc   7440 

gtatggacaa gagctaagta atgagaattg accgaaaaga tcccattggg ggtgagattc   7500 

catcgaaatt catcttgctc ctgtgccaac accaaatcag ctatgcgagg ccataaattg   7560 

tgccatgcgg ctaattttgc tccgattaaa tctcgtctcc atgaaaagct tggaggattg   7620 

ttttgaaaga tttatgagat agtcgattgt ttatgccttg ctatgttata gagacaagga   7680 

tattaatctc tcaacgaggc attacccaac catttatcct cccaaaacct tatttgagag   7740 

ctttccctaa tacgaaagga cctaaaccta agaaaatctt gtttggcttt cataaggcta   7800 

gcccaaaaat atgagtcccc cgcttttcaa aaagcctgag ataaaggttg cgatcccaaa   7860 

tatttattac gtagcatatc ttgccataat tttggaacag aaaatagtat taataagggt   7920 

agcttagtaa ttgctcaatc ccagttcccc attccctgcc tagcggcatc atgccaaagt   7980 

ggtgaagtcc taagtagact tactatgttt tcaaccacac acaacccacc taaggcacgt   8040 

tgtgtcatgt tatatggaat accatttgtt gattggtaag tgttgtatac ttgtgtttca   8100 

tggtgagatt aatacaagaa ctactaggga aaagtttcat ttgtagtcat gtgtgcaaca   8160 

ttgctagaaa aatagtaact gtactgtaat tgcgaagcca aaaggaaatc gaagcaagtt   8220 

atacatgctg cagggcactt tagttaatat atgtacctta attagctgaa aatctcttta   8280 

tccaaatata gtatcatgac ggccattttg attttgcagt acattggaag agttgtttgt   8340 

ggattgtcat tgctctgagc tgatttactg tgttggtaca tggtactgct agttctgttg   8400 

actagaatct cagaaacaaa tacggctcat ttcaacgttg agaagatata ttgacgacat   8460 

ttggttgctt ccgttgcaat atctgtgctc ctttgtactt caattgcaat ttgcaaggtt   8520 

tgtctttctt cgattcaaat cactggacat ctgtctggtc aatttgcaag gtttgtcttt   8580 

cttcaattca aatcactgga catctgtctg gtcaaaatga agttcaccat gttgttcttt   8640 

gttgttagtg cttgtaattg ttgtaacata ttcagaaaca cattgttgta ccttgtgcta   8700 

agtgagaaac tatatttttg ttgtaccttg gtgcggtgca gcacgattgc tggtctgtat   8760 

ctgatatgcc acttatgttt tttaattaat aaaaaaactg tttttaataa tatgggaata   8820 

aacctttcaa tagattgttt ttctcttgca aatcttaacc ttttaacttt taggcacacc   8880 

tagctaccta catcctgcca ttgcgaataa atttgtggtt tgacaccacc atgctcatta   8940 

ctatgtgcaa ctcttcacaa gagccgagta ggcaaccaca gagcgtatgc tgatcacact   9000 

atgcatagta gtgagtggtt caatgaggga atgtggatcc taagtttatg cgcccaactt   9060 

tgatcgtccg ttttatttga gaaattttta taattagtat ttttgttgtt atgagatgat   9120 

aaaatataaa tagtacttta ctcatgactt atgtttttaa attttttcaa aaaattttca   9180 

aataagacag acgattaaag ttgggcgcgg aaaactatgg ttacacttaa aatgggacgg   9240 

agggagtact acccttatgt ccacagttag tgacaacatc actgggaagt aaatgtcaga   9300 

ggaacctcct ccttcgggca tcctcaatgt taaaccaaac aacaactata agacggaacc   9360 

cacatatatg tgtttttact tatagtcaat gctacaatgt ttaagatcat ctcttcacct   9420 

taagttggga ctcactagaa aaaataatat ctattaattc ttatagtatg aaggattcaa   9480 

accaacgtac atgttgaaaa gacataaagt aattttatat tccttatagc tagctttaag   9540 

gttaagttag ccatagcaat attctcttcc aaacacacct ccctatacat aaagttgtac   9600 

taagaatatt atcatatggc ttatggtcgc atttacatgc acattagaga tgcccttcaa   9660 

tcagagggat agaaaaaagt gagtgatgtt tagcaagact acagggccta cttgcttaca   9720 

tgcacaggag aaactatacc aaggctctgg ttagtttcca cacaaaaatt ttatacccta   9780 

tcacatcgaa tgtttaaaca cctgtatgaa gtattaaata taggctaaaa aaataattaa   9840 

ttgtgcagat tgcgactaat ttgcgagacg aatcttttaa gcctaattgc tctatgattt   9900 

aacaatgtgg tgctacagta aacatttgct aatgatggat taattaggct taataaattt   9960 

atctcgttgt ttaatgacgg attctgtaat tagtttttta ttagtgcccg aaacacccca  10020 

tgcgacaccc tatataatat ccgatgtgac atgccaaaac tttacagcct tggatctaaa  10080 

cacccccaag tgatattaat tgtatcatag tggattagga taatctaatt tggtgcaaat  10140 

agctgccatt agtacaataa cgatttttcc gtgcggtcga aagcggtttt tgcgtgcaaa  10200 

tcttccgccc gtctagaacg aagtgcctgt gaaaatccga tttttttcgt gcgggtgatg  10260 

cacccacacg tgtgtgcggg cacttaagtc acccgcacga gaaaataaaa aatcgaaaca  10320 

gaaaaaaaaa accaaaagcc gccctggaac cctaatccag ccgccgccgc tggcctgcct  10380 

gaggccagtc accgtcgtcc gcttggtcgc cggcaacgga tccaaacgcc cgaggctggg  10440 

agaccattgc cgccaccgca gtcatcgtcg ctgccctgcc cgaggcccgc cgctatcatc  10500 

ccaatggtcg ccggtgatgg atccaccctc cccacggtgg ccggcgacgg atccgcgctc  10560 

cccacggtgg caggcgacgg atccaccctc cccgtggtgg ccagcggcgg atccgctccg  10620 

ctgccaccac cctagccgat gctgccgcta cactcgccaa tgccgccgcc gccgctctca  10680 

ccgatgccgc tgccaccgcc gccctagccg aggctgctgc cgtcgccagg agtgggtaca  10740 

ggggagggtg gagagggaga gggagatggg aggagtgaga ggagagatgg gaggatgaga  10800 

gggagaggga gagggagtgg gagttggagt ggccgagtgg taggatggga agagatcaag  10860 

tggcgccggg agctaaaagg gtgggtgggc tatttttgcg tgcgggtcac ttaacaggtt  10920 

cgcacgcgaa aataagccta ttattgcgtg tggatctgtt aagaggcctg cctgcaaaaa  10980 

ttgttttttc cttgcggtca ttttaaagaa ccgcacacga aaatggagcg tgatttttgc  11040 

agacgcgacc acttacagtc cgtctgcaat ataaagtgag tcctgtacag gaaaattatt  11100 

tctatactag tgcgctttta gattttttgg cgtttggcaa actgattttt ttttaatcta  11160 

tatgtcgcaa acagtaaaac cactaagaga catgacagtt aagtaacaca attatataac  11220 

tgtaatttaa tttgtaaaac aaactacgac ggtcagtaaa ataacaagcc cagcgcagtg  11280 

tagcacaacc accataaagt aagcctgaag ttgtgaggtc ttccaacaaa aatgctgggt  11340 

ataggggata tagtagttca caagtgaata gcacagtgac cagagagcta gacaatatat  11400 

agatggatga ccagaagctt aaatcctaac catattatat acttgcattg atgcataata  11460 

gcattgacaa cattggtcct actatcttgt tacatttcat ttccaccgca tatatctcca  11520 

aacagagaga ttaatatatt ggcaacagta catgcaaata aggtcttata aaaaaatgga  11580 

tgtgctctta catacaatga atatcaaagt aaatgaaact acacataatg tacagaggca  11640 

ccgcgaacgc aaaaaagcta ggaatgatag gcaactcatc ggaaatcgac acctgctgca  11700 

aacagagggg gaaaaaaact acaaacggca ccagccagcc gcatctaaag ttctaaacac  11760 

gaatctctgg aacatgctgc atcttctgat gcattctgtt tttgtgccat tgagttttga  11820 

agtccctgtg caggtacaga agccagagct tcttcagggt ccgaagggac tcaatgccct  11880 

cagggactat atccagcttt gagagtgaca caacgtacaa accttcaatg gatggaagtg  11940 

ccccatccat gatctttagc tggttcacat tgggcatgtg ctttaagaca agtgtcttca  12000 

ggtggggaaa agactgtaga aagaaccaaa atgtttgcac tatgcatgtt gttcagtctc  12060 

aaataagtga ggttcggcaa atgcgaagcg agcatcccta gtggatcttc accaagatga  12120 

caccaactta gagctagata tttaagattt gtgccgttcc cgtgaaatat tgggcaatca  12180 

agtgtaccct tagcccatcg ccctctgatg attagtctgt ggagttctgt tgaccttggc  12240 

ctaagagcct cgaagcagag ttcctcattt tcatcttttg cagaaagaag caagctggaa  12300 

agaaatagcg aaaatatttg cacaatcagc agaacttatg ttgtcaatcc acacacttct  12360 

tagttgcatc aatttcttca gttgctcagc caggtctttg ctagactcca cagtttctag  12420 

agtctgcagc tcttgcaagt tggaaagttc tttaggggca tgcattccaa caaagtaccg  12480 

gaaatctgac tgcctctcat caacgtatct atcggctata aggtgtctta gcttcttgat  12540 

cttaacaata cttcgtggta gcttctcaat tttggtttgc ttgatgtcaa gcgtgtggag  12600 

gttagataac tttccaatag actccggaag tgatttgact ttggtgcgtc gtaagccaat  12660 

gtaacgtaga ttaaacatat tcccaataga agtcggcact tcagtaatct ctgagtcttg  12720 

cagctcaaga actgtaaggt agctagatcc acacaaaatt gaggataaca tctcaagggg  12780 

caatgaggtt gtcgaaagtg agatcagggt ccgaaggcgc atgaatttaa ctgttgatac  12840 

agtatcatca ctccatccac atgttgacaa gcgacgaact tccttatcca taagcaacat  12900 

tgtgccaaga tcattggctg aaccaaacct ctcctcttta gcaatagaaa gagccaatac  12960 

acgcacaatg tcatgcatct tacaggagtt taccctgcca atctcatcat tgtccacaac  13020 

ttccagcata ttccggtgga tcagttccat aaggtttccc tctgcgacat cctctagcgt  13080 

gttcttttct ttgcctagca caaagccttc tgcaacccac aacctcagaa ggctctcccg  13140 

tgtcattgtg tagtcttcag ggaacaagct acagtacaag aagcaatttc tgaggtctcc  13200 

tgataggtca tggtagctca aatttagaat tgctcggaca tgatcattgt ttgctagctc  13260 

agtccgaagc tgtttgtata ttttattcca aacaaattct gctgctggtc ttgaagacag  13320 

aaggcttcct atcgttacaa ttgctagtgg taggccatga cacctatcca ctatagaatt  13380 

agcaaccttc tctagctcct tggggcattt gtggcccttg ttatagaaag cccttctaca  13440 

gaagagttca aatgcatcag cgccattcaa aggctggagg ttgagacggc gtgttgaggt  13500 

agcaagggct gcaacatcat tctctcgagt tgtgatgatg actcgagttg cttgaagatt  13560 

ctggaatgca tcttgcatct gaaagtacac ttttttgtcc cagacatcat ccagcacaat  13620 

caaacatttg ctatcttcaa tctttttctt aatttcttct ttcaggtcat gtgcatccat  13680 

attgttcaag ctatcaagtg acagttcagt agacccaatc tttctaagga gctttcttaa  13740 

tagagcctcc acattgtagg tctgggagac aacaatccat gcatgagcag caaagttgac  13800 

cttttcacgc tcataaacat ttgtgactaa tgtggttttt cccaacccac ctataccaga  13860 

tactgttatc actgctctat ctggctcatc agagtacaac catccagcca gcaatctctt  13920 

gtggtcttca atccccacaa gatcttcatc tttgacaaga tatgggaagt tgtcgtgaga  13980 

ccgtggtctg ccagtctcag caagctggtt gggattgagc tgggaagggt gcaaccactg  14040 

ctctttaagc tttataactt gctggatttg cttctctaac ttgactacct cctcagcaat  14100 

atcactaaat accacgactt aatgagaacc tttaacgaag tacttcttca agaaaccttc  14160 

ttcctcaagt tgaatagcat gatatgagta cttgtccatt acgtcctcaa catggtaggc  14220 

taactttctc acctctgcaa tccaattctt tacaactata ccagtgaggt atgaggtgcc  14280 

tatctgtagt ataacactgt tcatgattgt cagttgcttc cttatttcct cgaccttctc  14340 

tggcatctcc ttcaaattag taaccttttc agacaccttg gcaatgacag cgttggcagc  14400 

ttcatctgct aacacgttgc caaccttttt gacagaaagg agcactgcct cagccatttg  14460 

ttctgaaaga acacacacca ttatgttaca aaagagaaca acaagtggct tgcgatttct  14520 

agtctccaat ttaacttata tatcaaagaa aatttttatt tattgatgcc tttaattatc  14580 

actattttcc tggagaaatg tgtgctttca ttgaacagaa ctccaatggt ttctgcatga  14640 

aatgtgtggc actgttcaga cttggataat aatggtccac tgtgagaaaa gaaataatgg  14700 

tactcatgca ccgtgtccat agagtaattc ttttaccaca agcatctatg atctcataaa  14760 

acgttttatg agaagttaat ggcatctcat aagatacaac tcagcaaata aatgacaagc  14820 

tttatttgat ttgcttgtgg gcacagagta ggattccaaa tcagaatggc aaacagtatc  14880 

atatatgaag gccagtgcta agttatattt tattaattga cttggaacat tttttttttg  14940 

acaccttact ttggagttcg gaaatcggct acgagatttt ctggacaaac tatgctttcg  15000 

gaagagctct cctgcttggc tcagtaaaag aaacattgct ataatgttat acatcatgaa  15060 

gtacagctat tctgtatgta gttgtttact ttaatttgag tatgcattta ttacatttca  15120 

ccaacataca tgtgtttagt tcctgaaatt ggggagaagt ttagggaaag ttggtagttt  15180 

ggaaaaaaag ttgggagttt atgtgtgtag gaaagttttg gatgtgatgt gatgtgatgg  15240 

aaagttggga gttgggggga agtttggtgt gaactaaaca caccctatac agcttcagct  15300 

gaagcaactt gtgggctgaa catagttcat acatattcaa agaaaataac tggttcatca  15360 

acaagacagt gagcagaaag actatacatt agacaagcaa gtttagcagc attacctgga  15420 

acattagact aacaactatg aagaacaaaa aaatgatccg tagaacagaa cacacaacaa  15480 

atacactgcc atactgagta gtgatttata tgcttgctca cctgctggaa gaccagagaa  15540 

cagggctgga gcgcaggtgc tgtacggtca atgtgcagaa ccctgcagga tcaaacaaga  15600 

gaggatgaga acccagtcag caaaacagtt tgtgatcgtg cccaaccggg gacaaaattt  15660 

ggcccaaaaa aaaaaaaaag cgccgc                                       15686 

 
           
             4  
             17953  
             DNA  
             Oryza sativa  
           
            4 

caccaccctc cctttcctaa gccggcacca cctaggacaa gatatggcga tgacgagtgc     60 

cgtatcttct tccgcttggg agggcaagtg cgggggctcg agcggcggca aaaagagagg    120 

agagaaagag aagagatggg gatggcgtgg tgaggatggg gctcggctct cctcttattg    180 

gcggcgtgag cttggcggga cgcggcgatc tggcggctag gcaccgcgag tccgggcata    240 

gccggctagc tgctacggcg agcggatgac gatgcggtgg cgcggcgacg tgatgacgat    300 

ggtgacggcg cgacgtcatg ggaagcggcg atggaacgcg aggtgacgcg cggggagcgg    360 

gtttggcgac gggataatgg tgacgcgcga cggacggcgg ctacggccgg gaatcgagcg    420 

gtagggttct tctcagagcg aggggacgcg agcggcgtca tgcggtggtg gcaacgcgac    480 

gcgagagaga gagataggcg cgggctcggc ggcttcccgg taggagacgg gcgacaaggc    540 

gcggtgtgac aagtggagag ggcgcgcgtc cgcgggagcc cgggatagga cggcgtggcg    600 

tcacgaggag gtggcgacgg gacgacgcgg cgccgtgtct cccggagaga aaccggagcg    660 

agggatggga tgtgattccc actgggatat gcggcttggc agggcgcggc tttggcgcga    720 

tgcggtcctg gcacggcgcg cggcgcatgg gagggcggct cggtgcgacg cagcactgcc    780 

acgactcagt gctcgggcga gacatttcgt cgaacatgtg gtgcgcgcgc gcgaccggtc    840 

ggaggaggaa gacaaacagc ggtgggctgg gccggtgcgg gaaggccatg ggccggcctg    900 

ctcggggaga gagaggagag gaaagggagt tgggctgagg gaagaaaaag gaaaaaaaga    960 

ggcccaaatg aatagtgacc tttgaccttt cacattttct ctaggatttg gaatttgaaa   1020 

ttttggggag tttttggagg aatctaattt gaattttgtc ctagggtttt gacaacaact   1080 

cgaggggatt tctaagagag gatttgagac ctatttggca caaaatcaaa taagaaccaa   1140 

atttatactc aaaatgttta aatgacaaga tttttaaata aatgaaaaat tcaagggtgc   1200 

tacaaaatta caaagagcct ctttaaggta aataaagcat gcaacttcta gacacagatt   1260 

tctgcaacat gcagcatctt cttgtgcatc tcattaccat tccattggat tttgaagtct   1320 

ttatgcaggt tcaacaggga gagcttcttc agggagttaa gggactcaat gccttgaggg   1380 

accttgtcca gcttcggcag caacacaatg tacaaacatt caatgcatgg aagggcgcca   1440 

tccatgatct ttatctgctt gacatcaggc atctgcctca agacaagagt ctttagtttg   1500 

gggaatgcct ttgcacgaag aactaatgtt gctgcactct gcatgttgtt cagttttaga   1560 

taagtgaggt ccgacaagtt cgacgcaagc atccccaatg gatcttcccc gagatgacac   1620 

caacttaggg ataaatattt gagatgtgta ctgtggctac ggaatatcgg gtagtccaat   1680 

gtactcttgg cccattgccc tctgacaatt aacctgtgga gttctgtgga acttggcttg   1740 

agagcctcaa aagaaagtgg ctcattctca ttccttgcag aaagaagcaa actggaaagt   1800 

agcggcatat ttgacagtgt agcaaaaata ttatcacaat cagcagagct tatgttgtca   1860 

atccatacac tttttagttg tatgagtttc ttcaactgct cagctaagtc cttgctggct   1920 

tcaacagtct ccagagtttg tagttctttc aggttggata gatctttagg tgcctgcatt   1980 

cctacaaagt atcggaactc cgactgcttc tcgtcaacac atctatcagc aaacaagtgt   2040 

cttagcttct tgattttagt gattcctcgt ggtagcttct ctatctttgt ttgcttcatg   2100 

tccagagtgt ggaggttcag caacttttca atggagtctg ggagtgactt aaccttggtc   2160 

ctccgtaagc caatgtaacg tagattaaac aaattcccta tagatggtgg aacttgagtg   2220 

atttctgaat cttgaagctc gagaacagta aggtagcttg agtgagacaa aactgaggac   2280 

aacatatcaa tggaagatga aaatgcttca agtgatacta tggttcgaag acgtagaagt   2340 

ttgagaattg gtgcagtact gtctttccat cggtaagttg acagacgacg aacatcctta   2400 

tcaatctcta ccattgtgcc aaaatcattt gcagagccaa acttctcctc tttagcagca   2460 

gaaagggcca ggtctcgcat aatgtcatgc attccacaag tattcaccct gccgagatca   2520 

tcatactctg taacttgaag catattcctg tatatcaatt ccatgagatt tccctcagct   2580 

actgcctctg gtgtgttgtt ctctttcctc aggacaaagc cttctgcaat ccacagacgc   2640 

acaaggctct cacgggagag cgggtagtct tccgggaata ggctgcagta caaaaagcag   2700 

tttcttaggt ctcctgacag gtcatggtag ctcatattta aaattgctcg gacatgattg   2760 

ttctttgaca actcacttct aagttgattg tatgcttgat tccaaacata atgtgaccgt   2820 

gatcttgaag acaggaggca gcctattgac acaattgcta gtggaaggcc ctgacaccgc   2880 

tcaactatag atttggcaac tttcacgagt tccgtgggac actcatggtc cttaatgtta   2940 

taaaatgccc ttctgcagaa tagatcaaag ccatgaatat cactcaatgg ctggagatca   3000 

aggtgacatg ttgaggaagc aagagctgcc acatgattct tccgtgttgt gattattacg   3060 

cgacttcctt ggtcattctg gaatgcatca cgtatttgaa agtatgcttc ttggtcccag   3120 

acatcatcaa gtacgatcaa gcattttcta actttgagca ttcgctttat ttcctctttc   3180 

aaatcataca catccatttt gtcaatgtta cttgacagtg gtggttctgt gtaaccaact   3240 

ttccaaagca gcttccttaa tagagcatcc acagtgtagg tttgagacac aaccatccat   3300 

gcatgagcag agaagttgat cttttcacgt tcatacacat ttgtgaccag ggtggttttc   3360 

cccagtccgc ccatacctga cactgttatc accttactgt ccagctcgtc ggtgtacaac   3420 

cattcagtca gcagtctcct gttgtcttca atccccacaa gatcttcatc tttcacaagt   3480 

tctgggaagc tgtcccggga cctctgtctt tccatctcag tgagcgggtc agaaacaagc   3540 

tgggatggat gcaaccactg atccttcagt tctataactt gtttgatttc cttctctatc   3600 

ttgactacct cattagcaat ttcagtgaaa acaataacat aatgtgatgc tttgatgaag   3660 

tattttttaa ggaaccactc ttccgccatt tgcacagagt aatacgagta tttgtccatg   3720 

acatcctcaa cacggtaggc caccttcctt acctccccaa tccaaccctt gacgacttca   3780 

tcagtgaggt atgtcgtgcc tatctgcaat ataacgttgt tcatggttgt caattgtttc   3840 

ctcatttgct caatcttctc atccagatcc tttagattat taaccttttc agacagtttg   3900 

gcaatcaatt ctttagcgat ttcatttgct aaagcatcac cgatcttcgt tagagcaagg   3960 

aggaccgcct ctgccatttg tgctgaacaa aataaacata ttatcatgtt atggacatac   4020 

aaatatcacc caaagttttt ggcctcagtt ttactttgat gttgaaaatt ggaaacactt   4080 

ttctattgta gaccatagtc agactatgat aataatgaca ctactggatg aggctcatga   4140 

tgtataactt agcaattaaa tcagtaacac gggccatgaa tcaaggttag atctaatcta   4200 

tattaatgca tttacttgga acaacctagc aacatcaaaa acaaaactgc tcatgtttca   4260 

gtcacgtcat acctagatcg gaagatacct tttcaatttt tttttaaaag aactacagta   4320 

ggtaagtaga gagaaaccgg ttaattaaga taaagctcca atttattgag ggattaaatg   4380 

ataattcttg gagggtatct ttttaattaa aaataataag taaaaaaact gccgacaggg   4440 

aaacaaactt gggtggtgag gttcaattcc caaactccag ttaaaaaatt tgagagaaag   4500 

tgtgagttct ttcattagat tgtatctata tctaacatac tatgctgttg ggaagtgctt   4560 

gggtcagtaa aagaaacatt attatacaca agcgatgtaa tagcaattca aaatctgctt   4620 

gtttacatca atttgagtat cgatttactg tttagtactt aactataata taaccctttg   4680 

cttgtctgag acattaattt tgtggaacga atgaatttgt tgtggttcac aacaaaataa   4740 

taaatgaatc agcaaggtac tgaatgataa aactagtatt agataagcat gtaatatttc   4800 

ttggaacatg gttgcattta taaaataaaa ggaaaagtat attttacttc cctaaattat   4860 

ttggctgaag cagttaatcc taagcaattt taagttcgct ctattccctg aactactaaa   4920 

actggctagc ttaactctct cgttgctttg tcgtttttgt ttgtccttac acaagatgtg   4980 

ttttaaactg aaattgtgtg agatgatatg ctcgctcagg gtcaaatttc agaacaaatt   5040 

tcccaatatt ttctagcaaa gagactagtt agtgatccct cctctcaaca aggcgaaatt   5100 

cacgaaagaa aaaggcagaa ttttccagca gacataatca gaaaagttaa agctgatgac   5160 

agctacaaac tagctagatg atacaaagca agatccagtg gaaatcaatc taacctgagc   5220 

tgcagacgat cagagcgtct agaagagcag agctggcgag acgatcagag catgtgaggt   5280 

ttaagatagg caacgaagaa aatataaagc acaaagccac tagcctcaaa tctcaatcag   5340 

atccttgtct gtttctctga actagccgcc gacgacttga cgcgaagtcg acgcggctaa   5400 

gcatttgcag tgccaattat caactggcca agttgtgcgt gtaggacggg agtccgctgt   5460 

ggaagcttcc tttttcctga tctcaaaatt tatagtatac cctccaaacc gcatgcagtg   5520 

ggggatgctg gattcttttt aaatggacca gaaactcgag aaattattgc tcaatagatt   5580 

attttgccta tagtaaaaag gaaaagaaaa agtaaatcag aattgttcat atcgaaagga   5640 

atagaatatc tgtagtccag tatgcaaatt agaaaagata cagttttgat tagtttactg   5700 

tcctgcagcc agctcactgg tcaggctgtt cgctgcatct tggacatata ctcgctttgc   5760 

ccaaaatata agggattttg gacggatgag atattttttt agtacaagga atctggacat   5820 

gtactagtaa gtgttgcatc tgtttaaaat cctttatatt taggtacgaa tggagtagga   5880 

agaaacatat tgttatattt gaggatggag ggagtaggaa gaaacatacc gtgtcacctt   5940 

aacagtcctt gtacttatga ctcagttgtt gaggacctag ttagctagtc ggcaactgca   6000 

aaaatataat tccagtctcc ttattctact cactaatgac agcttagaga aagctaacaa   6060 

actgatttct tatgttttca tccaactaaa acggccggag acctccaagt cgtcttagta   6120 

taaaaatctc tcaagtcaag tttcctcgat ttcttggtcg tcgtcttcgt ccaccttttg   6180 

gtatgctcga ttttttaaaa aaaattatga ctctttttgt aaaacttatt tcataaatag   6240 

accctccaaa aatctaatta tggatatgga ctctactcgg tgccggtgag cttggcatcg   6300 

aggtttcatg cacccacgct ggagaccttg gcatcgagtt agagggggag ggggagagag   6360 

tgtcgatgtt gtagatcacg actatggtat ttgcaaagtt tggggatcat tcgtaccagg   6420 

gtataagcga gactaaggta aaatagacgg agacaaggat tttcatgtag gttcaggctc   6480 

cttatttaac aggtaatagc cctactcctg ctaattgaaa ccagtgttgc tcttattcat   6540 

cagaatcaca caagtacaat atttgggata actctaatca tcgtcaacac ggcggcatga   6600 

accaccacac gttgtcgaca acagggtagt cctcctcctc taatatgaac tgggcgatat   6660 

cagagatagc gctagatccc tcttgttagc ctctgtggca ccagattgga tctgtttagg   6720 

tttatctctt atgttgatgt ctggcggcat gtattgatgt atattctgac tgttgcctgt   6780 

ctatttagac tcggcttgtc ttggtccgtc tccccctctt cttttagggg tcttgtattt   6840 

ataaccatag atgtcccctt atccaaatag aactagaaag ataaatatgg atacgatccg   6900 

aatagtcctt gtagtttcca tatagaactc tgcttctcct tccttatctg gaataccttc   6960 

catatgcaag atttgatttc atataagact tggtatatgg tgggtcccgt tgagcttaac   7020 

ccaacactat tgggtatgcc ttacccataa aactgacagg gggtaggcgc catgcttctt   7080 

ggtgcggaca ccgagttgtc ccgagatggc atgggatggc atgagtgtac agcgagcacc   7140 

aagagtctga gacaccatgg aatggcacgt gtttggcaac ttttttgaca agtagacaaa   7200 

cacgatcgag acacctaaac gccttgcggt gattgtagtg tcgccaacca cctcaatcta   7260 

gcaaaagcta gaccaagatg ggttttgata aactaaaccg gctagcggag ccgatttaga   7320 

tagaacaata gataactatc cgtctcgtgg gtaaacggaa ggtttacggg acaaacctac   7380 

aaaggatttc gcactctcgt agtgaagaca gacgatttat ggcacaaatc gacaaagatg   7440 

gatgaactag actagaacta gattgaaata ttgaaaaagc gatttaattg gctaagttgg   7500 

attgtgtgta gattgtatgc tcaattgaac cggccttgtc ccttatatag gggttgatct   7560 

tgcctcctac aggtcctcct ccacgtcgaa ctcgggatag aattcaaagg aaacccgaaa   7620 

tatagcctcc tgagtaagga atcctgagac atgacgaaaa cagactcggg cttggactct   7680 

gctggtctga ccggccacat gccgccggac agaccggccc tcaagcagcg gtctgaccga   7740 

ccaacaaacg acggtcagac cggccctatg gaggaaaccg gcggttttcc caaatcttag   7800 

caattttcct taatttgaac agacaaacga tgatgatgag catggcccac ctcaaccctc   7860 

cctcttctcc atttcaatcc ctgccttttt atcagttgat tctatcttat ttttcctcta   7920 

tgtagctcct aatgttacta cttcctctat ttcatactac aagactttct agcattgctc   7980 

gcatataaga tagaatatac tacaagactt ttttttctta acggcaacat atcctatgca   8040 

cacaggccct cacgtgtaca cacgtgcaca ccaactaaaa aatgtcacca aaaaatttag   8100 

aaaaaatcat acacatactt tcaattgtat tacacctagg gttaaaatct taacgtcaaa   8160 

ttcattatat tttagccgta acaaaaaaaa caaaaaatct gacagtttta aggttgcaat   8220 

tttgtcagaa ttttatcttt tttgttattc tctatataga atgaatttga agatgcgact   8280 

ttgcacgttg atgtaatact attgaaagta catgtatgaa ttttcctaga attttttgtg   8340 

ataattttta gttggtgtac acggtgtgta cacgcgaata tatatatata tatgtgtgtg   8400 

tgtgtgtgtt aatgaatcta gacatatata tatgtgttta gatttattaa catctatata   8460 

aatgtgagta atgctaaaaa gtcttataat ataaaacaga gtgagtaata ttttttttct   8520 

atggaaatct tgaataccca tcccgaaaat catgtctctg tcactaatag ggctagtggc   8580 

atttggccaa gcgttggtcg ggttggtatg tgcaggagtt actagcacgt gtggtggagg   8640 

tttttttttt ctttttcctt gataataatt tcgtagggtt ataatctttt gtactttttc   8700 

ccagctttat caatatgaaa tttcacacca tcttatctta tgtgtgggcc attttggaaa   8760 

aaaaaaactg agctgcaatt gtatcgcttt cagtaacacc agaccacgcg atcattttta   8820 

ccgtgactcg gtggttgatg acctatagct tagctagttg gcacaactgt agatccgatt   8880 

gctccataca atccgtctgc ttattctaat cactactggt agctaatgga acgtaaaacg   8940 

aggaagtcat tgccattttg attaattaaa ttttaattat tttaaactta aaaatggatt   9000 

tatttgatat tttaaaacaa cttgtatata acaagttttc acacgaaata taccatttaa   9060 

ctgtttgaaa agcatgctaa cgaaaaccaa ggtaaaatct gtataatcaa agttagaacg   9120 

gggttagaga aaagccaata aaacggccgt ggacctgaaa agtttcatta gaatacacct   9180 

ctcaagtcag tctcctctgc atcctggtcg tcgccttcgt ctacctctcg cctcgccgtc   9240 

gccggaagag gagctaaccg gctggagatc gattgatcca acatgagtga caatcctcca   9300 

ggtatgtgca tgctacaagc ttaaccaatc atccataggc gaactatttc acgtttgaat   9360 

aacatatttt ctgtaaattt tcttactttg tgggtgttgt tcatatgcag gctacttcgt   9420 

tggtcgccca ttgaaccatg aagaacagca agcttcacgg ccggctgagg aacagaacgc   9480 

tcaattccct ggtaggtata caggattaat tagttttctg catacatcaa tttgcttagt   9540 

tttctgcata catcaatttg ccggatatga tgtagcagat cttgttataa cttgaggttg   9600 

ataagtgctt tgaaaagggt tcttaatttt cagtcttcta tgcattcttc tattacctca   9660 

ggctgttttg tttgctatgt cctatgatag ttttcaactt ttcaaatttc aaatccttat   9720 

aaagattaag agaaatcttt atcttctgat tttccttttc tactactaag gctactacaa   9780 

tggcaatccg gtcagaccaa atgatgctaa gggtgcacag aggaatgaac cgggcttctt   9840 

taagaaactg taagctgcaa ttcgtgtaca gaatatcaga tgcttctgtc tgtagttacc   9900 

cattgatttg tttttctctt tgcatgatgc attggctcat tgaatctctg cagcttcggg   9960 

tgcttcactg gcggtcaaaa tgtgaactag atcaacacgg ctgtattcgc aatgttaatc  10020 

gacagttcat caagaaatca gtggaatttt gatggagaag ttatcatttt aggaaataca  10080 

agttttgttt cttccaaagt ttttcttttc ctgcagttac actgttgtga attgtacaat  10140 

catatcccaa gcaaatgaga ttattccgcg ttatccatta gtattttgct tacctgtttg  10200 

gatctatcaa tttactatat tgctactggt ctcattaaaa ggattgtttt atccaagtcg  10260 

tctttgtcaa ggaaaaggtc cacatgaata tgaaaacttt gaactttctc ttggatggtt  10320 

cagaaatttt ttttgactca atcgcctatt aattacaacg aacaatcatt tgtcattttc  10380 

aacgaaaaag aataataatg tttgcaaacg agagcagcga tcaatgagat gactttgaca  10440 

attgaccgac ttatttgcaa ctgcaagtct tcaagcaatt gaaccaaact gtcatggatt  10500 

ttaatttttc agcgtttgct ttgagatgaa aatgactata aattaactgg aaaagttcta  10560 

agactcttcg ctgacaagga ttgataggta ttctggtatt tggcatgctt gtggtcttca  10620 

ttaattaatc ctggttcagg gtaaataaac ttggacaata atcaattatt atactcattc  10680 

aaatcaaggc ctggtttaat tcctaacttt ttgttcaaac ttccaacttt tccatcacat  10740 

caaaactttt ctacgcacac aaactttcaa cttttccatc acatcgttcc aatttcaatc  10800 

aaacttctaa ttttgacgtg aacaaacaca ccccaaatta cacttagaat cttatattcg  10860 

ccaccagtcc atactatact aatcaagtag acacctttac tttcatctaa tttccaagac  10920 

taacagccaa tgcatcaacc ttatggacta tcatattgaa acattttata tcatgttcct  10980 

tttgcaatac ttatttacaa atacaatcct atgaaactta attgtaggaa tgaaccccaa  11040 

tctcagtcac agccaagccc aagcttagga gtgaactcca acatcttagc accaacaagc  11100 

aggtcactta gttactactc cctccgtcct aaaatgtaag atttttagct atgaatttgg  11160 

acacgtatgt gtccagattc atagctaaaa attgctatat tttgggacgg aggtagtata  11220 

ttaatcttgc ttctagcatg gtgccattgg tcaactccaa ggatttttgt gctgagatgt  11280 

tagaagtttt agggtccatt tgtgcgatca gtttttaagg gtttgttctt aaaataagta  11340 

ttgaaaaaga acacaaatgt gtaaaatctt caggggctac ttaaaagaaa aagctttttg  11400 

cagacagtca aaagtgattt acacaagtgg ccagccatta tgtctacaat ttaaggcctg  11460 

cgaaaatcat gcatctttca cattgattga tattctgtct tcaaaagcat catacattta  11520 

tcattgatat gtaggtttat gattcatcag acctatatat cagtaataaa gtcacatgcc  11580 

tttcaatgta gaagaggccg atctctttca cttgcagcca aactaacacg gcccaaatat  11640 

ctgtaagaca atgaagtttt ccctgtcatg acaacttaca agatccagag tatctgtcct  11700 

aactaaaacg gttgccagta cggtgaaaat aaaaaaaaca aacagtggat gatttgatat  11760 

tctcattgca tgccatgttt gcaatttcgt ggaaagaaat aacaaatagt ggatgctttg  11820 

atattctcta tctcatgcca tgtttgcaaa ttcctgatac tctagttact gagctggtct  11880 

tcgagtagta gtggtcgctg gttggtgatg ccacttgagc aacgacttgg gttttaggtc  11940 

gtcgcggccg aaaaaaatat caatctctgc gcgaatcatt ggcgtaggcc agcctgggag  12000 

agaggaagga agcatcttcc tgtgcctctc cttaccctct tcgtcttctt ctccatctcc  12060 

ttgtgtgctc agtagcttct cctcctacga aaccaaccag ctgccgccgg tgaccgtcga  12120 

tccgtcgacc gccgccgcca tgagcagcga tgttcctggt acgtgtcact cactcacaag  12180 

ctttctcttc tcttcttttt tttttgtttg tatcaatcaa tcatgctaaa gcctaaagga  12240 

attcttgctt ctttatatca gtctaagaat ttttcggtgt gtgtgtacgt ttgttgcagg  12300 

gtacttcgtg gggcggccga tgaaccaagc ggagcctgcg aaagaacagc agcagggcgc  12360 

cgacgagcag cggcctgcta ccaacgcgca gatccctggt ggtacgtcca acggtgcaaa  12420 

ctcgatttga tgatcaaatt ttggccgcaa aagaatcggt tttgcccgat gttttgctga  12480 

actttgcttc gttttcgttt tatgtaatcg ttttgggaca caaaaatgag tcgattttgt  12540 

ccggttggtt tgctaaattt ttgcttcgtt ttcatttttt gggggggaga agactacttc  12600 

gtcgggcgtc cggcaaaccc gcagcagccg ccgtcgcaac ctccgcgggc gcaggagaga  12660 

tcgagcttct tggccaaatg gtactccaat ttgttcttcg aaaatcgaac aacaattgtt  12720 

tagattgtat tagatttcat atcgatttgt cactctgatg ctttgctctt gctgatttct  12780 

ctgtttcgtt tctgcagctg cccatgcctc gacagccgag ctgagggata gacgaacaag  12840 

tgcggcggcg ggcgtgaccg taaattcgat gggaaaattg aagcaaattt gcttggagtg  12900 

ataaggctcg gatctgtgtt tgtgttgcaa gttttgctaa tagatgtttg taactgaagg  12960 

ttgcttctat tcatttgtat accaattgtt cattcgtatc atcagagtgc gaattcgatg  13020 

aaattgtcca ttccaatccg gcatgccttt tctccttcct tgaaatgaat attctgctcc  13080 

attgctggca aatgtcaaga atgagtttgt tgttttattc agtactgatg ttgattgcat  13140 

ggttatcccg aatttgtttc cctttttttt gtgaaaataa atccaaatct ttaagttcat  13200 

ctttgataaa aaaaattctt tctttgctag aaaatatata tattgtttta gtcaattttg  13260 

caacttgcgt gcatatgttt ttgccacagc tctccacagt acatgtacga agcaacttga  13320 

tgaactaata ttgtaccaat taagaaagcg aaaatcattc ccagcaaaat aaaagaaaga  13380 

gaactatgtt cggattccag cggaaaatag tttaatagtg ctagaattac tccatgggga  13440 

ttatttttga tgatttattt gacagctgaa tgtgagtgtt aacctaatgt ttgattcccc  13500 

caatcttgtc tgcaggatgc gagaccactt ttttttttga atgaaatgat gagacgattt  13560 

gtggctttaa aatatcgtat ttgttttgtt ggacaaccta gcaaccaatc attttctgct  13620 

cacttggtag cgagtttttt ttagttgttt gatcagaatc atagttgtat cacatggaat  13680 

ttgtagttct acttagaaaa aatgcccgtg cgttgcaacg ggaagaaaat atgagaaaat  13740 

taaggagaag ttgaaaaaga tttacattat gtaattaact taaatacaaa tttcctgaaa  13800 

tagttgatat tttttaagta ggtatgtgtt taaattaatt taaaagtaaa ttaagtgtgg  13860 

aaatacaatg atatggctgg atttaatttt tatgaagttc tccatgatta attacgctct  13920 

ctagaatttt cttgaaattt tcagagctta gttgcgaatt ttaataatac aaacatcatt  13980 

tcagcattta tttaaaaaaa tctaaataaa aaccctcctt tctctttggg ccattttcag  14040 

cccgtttcct tcctcagccc acagccagcc gacccacttt tctcccttct cctcccctcc  14100 

gcctcggccc gcaagtacgc atccggcccg gcaaggcact acaagtctaa tcatcctccc  14160 

cactcctttc ccagtcacgt gggcacgtgg tccggtgcta cagggttgtc tcctacctct  14220 

gtctatattg tcgcatctgc ccgacgacgc ctgaatccac ctcctccgta aaatccggtc  14280 

acatccttgg agataatctg aaattaactg agaggttttg atacttatct tctcctcttt  14340 

ccgttttccc aagaatcaaa gcaaaaccac gtcgtataaa tgtcggaagc gaaaccctag  14400 

ttttttttag tctaggccca tttctcttaa aaaaaaactg cgcaagcatt cgcgagaggg  14460 

gggaggaatt ggaccatatg gataaaaaaa agtgtgacga aaggaaaaat acgaattttt  14520 

taattagtta agatactaat gaattttaag gtaatacaat agttagtgcc taattgtcaa  14580 

gaggcaaatt atatgtaaat aaagataatt atattatata gaagttgggt ggtaaacgcc  14640 

ctgacgcaaa aaattcatga aaccatccgt cccaaaataa atcaatatag ggttgtatgt  14700 

gatattattt agtataataa atctggatat atattatatt ggtttattat aagacgaaat  14760 

gagtagcgtt gtaagtatcg agtactaatc cctctcttgg gtaaagggac acgcagagct  14820 

accaaacgaa catactctgt ttttaataga cgatgatgtt tgatttttaa cacaaaactt  14880 

tatatatttt tcttattaaa aaatttgtgc aaatacatta tacttaaagt atttttagtg  14940 

ataaaataac ccacaataaa ataaattata attatgtaat ctttttaata agatgaatga  15000 

tctaatatgt attaaaagct aacggtgccg tctattaaaa gatgatgaac gtagtatatt  15060 

accattcgaa tttatttaag ttttgcatgc tccgtatgct ccaactattt tctttttttt  15120 

aaaaaataat caatcatcaa tgtaaaagtg ccatccttgt cactaggaat tctctatata  15180 

cccgtagctt ttaactattt gccattttta gatttgacaa ataactattt gtcaccccta  15240 

tctcaatgac atgtgggtcc acatgtgtct atgacatata gatctagtgg caaaaagtta  15300 

attgccacat ccaaaagtgg caaatggtta aatatctccg gaaatggcgc caactgaacg  15360 

tgctccactg gccggtgtgg atggttgact tagtcagcgc actggtagcg aactatagta  15420 

gtagcgatta gcgatggaat ggcagcgttg acttgacaaa taaaaaagtg agaaaaacca  15480 

agctgcagct tgcagccagc tagctcattc cgtctcttct ctttagctca ccctcacacc  15540 

tcgcccatag agtcaaaggt cgtcgcctcc tctcccatca gcgagccgct ccattgcgag  15600 

ctcatcaacc aattaatcca gatacgtgat gatccatgcc ttcgcttgca aatcgatttg  15660 

tgctttagtt aagcggactt ctgcccaaca tttctttctg ccccgattta gacggagatt  15720 

aattagtttt ggtggatttt tttgtttttt agcgtttgag catgagaagc tagtggttgt  15780 

tgggattgtg atccggttcg gatctttggt gatgaaatcg tcatgctcgc ccggccacct  15840 

cggttgcctg tgcgaccaac gccgtgtcgc gtcaccggtc gcccacgacg tgttcggcgt  15900 

aaggcgccaa agcgaccggg agaatatgta ggccagtagc ggcggcgccg gcggccggat  15960 

tgccgattcg tgcggtgttt ggagtttggc ctgcagtcga tgtgatgtta ttattatcgc  16020 

cggccgcgcc ggcgcggccg gagtgcgttg tcgcggccac cgtgccaaga tgtaccactc  16080 

ctgctttatt tctagggcca aatcttagga aattttcgaa agttgtaatg tcctgtgcct  16140 

agatggctaa gctgtgttgg tttacgcaaa gctcgttagg attcaagtac tggatttggc  16200 

acaagacgtc atcaatttta tgagtgctct gccacttcca gctggttgga gtcgtacttt  16260 

ccgagtcttt tttcctttgg tcttttgttt ccctcctctc ttggcataag tcggtctggc  16320 

ttaatgcgtt gtgtaacgaa tattcttatc ttctaatata ttgacgtgca atccttttgc  16380 

gcgttcgaga aaaaaaaaca attttatgag taggaacgcg tttttgttca atggatatgt  16440 

gtatgtggtc tggggacatt tgttagtgcc ttcaacaatt tctaagcgtg tagagaacaa  16500 

ccgtgaccct gaccttcttg caaacaacgc tgctgctgtc tttgtctttg gatgtgttct  16560 

tatcctattt ctgtaataat gctgcaggtt tcggcacacc aactgtttgg gcaccactgt  16620 

tctgcccccc cccccttccc tagctcgcca acaaatctta cagcaggtga gctagcacta  16680 

gttcatcata attcatagga attgtcaagt gcatgagttg catggtcagt ttcttcagaa  16740 

tgctgctttc aggtccagta gttgttaatc tgacttcttt gcgaaaaagc cattttttct  16800 

ctcttaaatt actttgttga agtgtaattt tacttctcag acaactaatg ttttagtttg  16860 

aaattttgtg gggcgataga tgatactgta atttatattg ctaaacattt tcaaaaatct  16920 

tcatcactat ttacatgcat ttccatttat tagaagacaa actggtcttc tgtgctcaaa  16980 

atctatacat tctcgtacaa attgaattga aaacacagct tgtgcaagga gaaacaaaaa  17040 

aatacaaatg caacaaggga gttaatgaaa caagctttca gttctgtttg gggagcttaa  17100 

gattctgaga agtagctggt tggtagctag cttctgataa tctggaaaag ttgggttttt  17160 

caacttctgg cttctataac tacagattct tagaacctga gtgagaatgt agactatttg  17220 

aggagctgga aattctaaaa gaaactgcaa atactagaag ctcactcaaa cagggcctta  17280 

gtacttgaag gagtaaagtg aactagaata aagtctaggg agttaaatgc ttcaacgaaa  17340 

tatttagggg agtgaaatat acatctttca tttattttta tgaggataac catgcttgct  17400 

tctctaatta tactagtttt gtgattaagt ggtttattgt tattttattt gacacaaagc  17460 

gtgtaattta gcccatatac aaatgatata tgttggttac ttaactgtag taaatggata  17520 

ctcaaattga tgtaaataag atgtgaaatt gttattccat cccttggtgt agactaatac  17580 

gtcttttatt gacccaagca cttcctaaca gcatgtgtct tgagttgttt acttgtattt  17640 

cccgacgctt tacttacttg acagttagta ggacctgcct ggtggcccat tattcatgcc  17700 

attaacatct ttagttatta gaattgttct gtgccttcaa agatctgtga gctccatgtt  17760 

tcccacatct gattagcatg tacacaatct aatgaaagaa ctcgcacttt ctctccaaca  17820 

tttagaatta gagttcagga attgaacatc actacccatg tttggttccc ggctggctca  17880 

aattttgttt agtttcttct taactaatag catatctagt tcctcctagg attctaattt  17940 

aataccttaa taa                                                     17953 

 
           
             5  
             91552  
             DNA  
             Oryza sativa  
           
            5 

ggatccacta atcctcctcc tcatcgtcga gctgtcgccg cacagctgct tctgcatgag     60 

gacaatggga gatggcgagg agagcgcttc ttcatgctat ggtgagagag aagagaggga    120 

gagggctcct ctttattgcc aagccgctat ccctccatgc attattgacc caaaggtatg    180 

ctcgagtgca taattagatg ggcaaatgag taaatgactc actgtaacgc cccgcaataa    240 

ttagagaaaa agaaaagaga gaaaagagca aactagcagc ccagctaagc cttgggcctt    300 

ggcccatgcg tgcagcccag caagtagcaa gcagcagcag gccagcccat gcatgcatgc    360 

agcccacagc agcaacatga agcagcagta gctagcatgc agcagcgagc agagcaagag    420 

cagcagcaac agctgtagct aactttagtc ccacctcgcc aatttgagaa gagagggagc    480 

agcttataag gaaggcagca cggtcgctag gaattctgat tttggaattt ttgcgttaaa    540 

gcgaggtcga tagtgttaaa tagtgttaag tgtgattcaa ctcagatgga tccgataccg    600 

ttttcgggct ggtaaacttc gtcgagtata ttgctttctc tactgttaga aataacattt    660 

tgagttcaac aacatagaca acttaaaagc atcagtgata cggtagtgaa gtcatgagtt    720 

atacccacaa atattatgca tatgtaagtg ggctttcaac acgaatttaa tcagtgaaat    780 

catatacgtg ctgctgattt tcatctattt gagagtgtgt tagggagcgt attcgtgagt    840 

gtgtgagtgt ggtgttacat gtacagtgat atatgtgcat gtgagtttgt tgtgtaataa    900 

aaaaaaagaa ttactcatta taataatctt ctgaacatct cgcaaaaccg aaaattttgt    960 

gatccattaa caccctaggt ggctaggcca gaagaagccc aaagaacaca attccacatt   1020 

ggacctagaa gaataagacc aaactagaat aatcaaacat atataaacaa tgctcaaatt   1080 

gttcatctcg agcagagttg ggtcgcgtcg gctcacccca gtggcaacta atcccagccc   1140 

gccttatggc atagtctggg tggtggaggg agcagtagcc ccccagcaag cgctcgccgc   1200 

cgacaatgat gacgacgact atagcgactg acggggcggc ggcagcctgc ccgcctgctt   1260 

tggtgccgag ctcctatgca tcggccatca agctcccatg cggcgtcggc tctttcttgg   1320 

atttcgtggt aaggattcgg actcagtttc ctatggtttt attgggggtt tctattcaat   1380 

ttgttccata gagatatccc aacccaaatg tgttggtctc gattttaggg gttcctctcg   1440 

acgttcgtgg gctagggctt tcagtctttg ttgctccatt cttgcaggct tgcagcatgt   1500 

ttcatgtggc tgcaaattca ccacatgtaa gcaaagaggg ttcacagctc cacagttcac   1560 

acagtagtgc agcaatgtgc aagttctagc attgccatgg cataatgtgg gaattctctg   1620 

gctttcttta ggttagaaca atggattagt atgtgctctc gtactccaat tgtatgagca   1680 

agattgcatt ctccaattcc agagaaaaaa aacccctaaa ctcaggtgat gcaatcctta   1740 

aatttcccta caaattcatc aattactatt atgaaagttt tttccatcca tgaggatgta   1800 

tcaggaggta ctaagtacca ccagtacgat tgaaatatgt ccgttcaatt cgcagggaca   1860 

cgatagtcat aaaaaaaaga gtggtttgat agggctgccc catgctggtg ttgactactt   1920 

gactttgcct tccatcctaa ttcatcgtcg ccgttttcgt cgcccctgct agcctactct   1980 

ctccctactc cccagcctca aactcctcct gatctagcgg caacggcagc gcactatccg   2040 

gagtgtggcc tcgtccccgt tctcaccacc ctcacctagg ggggtagcgg ggcggggcgg   2100 

ggccgggttg gataggaacc cccccgctcc ccgcattccc tcccccccag ctgttaacag   2160 

tgaaatttgg taagcccgga gtagtcatcg gcttagagtc agcatcggct ttgaagtcct   2220 

gcgattagcc gatgagaatt gtcaagtcgt cagttgtcgg attcttgcta tattcggtta   2280 

agaaaattga tctactaaag gaagcttatc tagaagagac cgagttcaaa gagaatgcgg   2340 

catggcaagt tatctattaa ttaggaatag tttgttagtt tccttttatc tttagaaaag   2400 

tgtgtttagt atcctataag gactttatct tttcctttta tctttaggaa agtttttttc   2460 

ttgtccgaca aggacttgta tcaacccatg ggtataaata tgtacacccg gggtctatgt   2520 

aatctatcac tacgatcaat acaattcggc gcatcgccac cctttttact tctacttttg   2580 

tttttacatt ccggcggaac ctggcacccg acgcggggct gcatcgtctt cgatctccgg   2640 

cgaagggata agtccaatgt tccgccggtc caggcaattg tatcgtctac gtcggcgtcg   2700 

ttcaaggctg catcagtaca ttcgacctat aggattactc tggtttggat aatatatttg   2760 

cctggctatt tatcatatgt ctatgttaat ctagtcctag catctcaatt tagctctatc   2820 

ggctgtctct cactttaggg tttctgccag tatcggctaa atcgctttgc tagattagat   2880 

tagcctagac atctaccacc ctgaaaatca gtcaacggct tgattgtcta gatattgtgt   2940 

ttcttttcat acttagtgct gcatcagtta agtttgatct actaagtcgt gcttagaacc   3000 

ataatctcta gcctgctttt tgattgccaa taagggtttc atcggggttt caaccggtga   3060 

gttatctgga cgttgcatcg gctcataagg attgcatata catataagtt ggatttagcc   3120 

gatgacaaca aaggtttcat tgtttaatct aatcttgtgg atttcatgac atcggacctc   3180 

cagccgatgt gtgctttaac cttcggatcg atgcttattt atcatatcaa tgctagccga   3240 

ttggcttata ctggattata ttgttatttt attacatcat catcagccga ttgtctttat   3300 

atcattatct acattggaca tatagccgat tgcttaaacc ctatcgctat cggctggtat   3360 

tggcatcggc tattatcggc tatcggctag aaccactcca tcggcttgtc agacgatcgg   3420 

ctatttgatc tactatttac atatcttgtc agttgcagga tcaaactgac tagcacgctc   3480 

gcatctcatc aacctttgta cctgcacagg agctaagcag atctcccaga ccggtgtgtt   3540 

cgattttttc atcaacacca gcccccgtcc ccgcccccgc attggtcacc acgtggaaaa   3600 

cctcccccgc ccctgcaggg agcccgacgg gtgagcgggg ccccgcacca tctgggtgga   3660 

gttggtactc tattgaaaca acacaacaca ctgaataaac aatgacatga tcacaataac   3720 

ttttcaagta ttattatgtg attgatgtta caagtgttgc taacatttca tatatagcca   3780 

tataggtacg acaactaggc aagttctatg cccacggaca agccgtgtgc tgattaataa   3840 

aatcttagga tagcatagcc cacattgagc cccatataaa ttaacactat aaaaaaagtc   3900 

tagcaccata aacttttagg ctaaggcctc gagccatgga ccaaattcct caagccccaa   3960 

atctgcattt gtgtgtggac aaatcccata aatgtaaata gcacctaata tatgccgacg   4020 

ttatatatga tttaccctat cctgaagcta ttttaaacta cactagcttt acggttacct   4080 

tatcttatct cattataatt taaattacac caaagtttcg ctctctatta tggtgtctta   4140 

tctttttcac tattttagag ctctttacgc gccattcacc taaaatagaa taccacgttt   4200 

ttcactataa aaagatcacc ctacctctgt cggcaaacac agaaaaacaa ctctcacaag   4260 

agtcattttc attactaggt tcgtgtccgt gcgcccgtgt aggtgaggtg tgctatggca   4320 

cggcatacca aaaacgctgc ccgcagagtg actcttagga ggcgtcgtgc tggattgatt   4380 

aaaaaggtaa cagagctatc aatcttgtgc agtgtccaag ctagtatcgt ggtgtacaac   4440 

atcgatgaag catgtgatcc agtggtatgg ccatctattg aagaggccaa aaacatgtgg   4500 

agcaaactca tggacatgcc agaggctgtc cagaagaagt ggatgcaaga ctccaagacc   4560 

ctactccagc agcaaattat gaagctccag aagaagctgg acaatctgaa ggctgagaac   4620 

tacaaacgtg agatcaccaa cataatttct gagataggag gtggacaccg caagaactta   4680 

aatgatttat ctcccgagat ggtcaaaaat gtcaagcggg aggcggccaa gctccgggag   4740 

gccattagaa accgcatcat cgagctccac gcacaaggtg cttcttcttc ggtggttgtg   4800 

gctccacaag tggaaatagt tgcaccacat gcttctcaat ttgatttgaa tgaacatgca   4860 

ctagtttaat atggcgtgcc catagtgagg gaagaggctg atctcccttg caactaaatg   4920 

tgctttgttt ggtgattacc ggttgcaagg aacatggcta gcctattact tgttgtatgt   4980 

gagaagaata ttgatatagt ttaattggtg gtaatgtttc atctattata agcttgttat   5040 

gataaataaa taaattgttg ttgcgtaagt aatagaaaaa tattttctct ggtaagaaat   5100 

agttaatgac ataatattgt aacgccatag ttttagtgag gcattaataa aaacctaatt   5160 

tcaaacgtgt gaattgtgct agaatgatac gatcaataaa tagtagaaaa atgattaagc   5220 

aatgttttat attgatattg tttgtggttt aaagctaata ttgaaaaata atgaactgca   5280 

ataacaatac ccaaaattaa ctttagaaaa atcaaatttc aagatttaaa tttttgctat   5340 

ggctgataag cgaataagta gacacttatg atagtcttgg tatcttcttt accaaaaaag   5400 

aaatgacgtt ttggatatcg atatactagt cctcaaggtc catgctatca tttctctctc   5460 

aaactatata ttagcaaaaa taatttaaat ataactgtat gaaatatctt tttttatgca   5520 

aaaactacta atatagtttc tgcattttaa atgctgataa ttttgtagta tgtattaatt   5580 

aatgatttaa ttaagatgtt aaggttacac attataacat gtcatcgaag gatagttgta   5640 

aactccgttg agtatattgc attctgtagc gttaggaaga acttgcattt tgactttttt   5700 

ttttactaca agaacgtaga tagatttgag attgtcttta gtgacagcta aagtgaacta   5760 

tttcaaaatg gtgtggcggg aacagtgcac ggacacggac atccgccact gtgccgtgtc   5820 

gcccgcgcag gtgaccacgc cggccgtctg gcaagccgtg ggttccctcc acgttcgctg   5880 

acgcactgga gcgcagggtg actccgtcat cgcctctgcc ggccgccgcg tggcgcgcgc   5940 

ctcccatcgc ttcactgcgc gccgccctca agagatggga aaaaagagtg aagagggaga   6000 

ggcagatgag ggagaagaga tgggccgctg acacgtgggg aaaatgcttt atatcgtacg   6060 

tccgatcaaa accgaaatat cggacgcgtc atctactgta aatcggtata tggataggat   6120 

gaactatttc actgtaacat ccatggccaa ttgtttcctt ttgttcttac ctcttctctt   6180 

taaatatttt ttcttctaga ttacttattc gatctacgaa ccgatcacac cgttatattt   6240 

gttgcaatta aatctttaca ataagatatc atatgattat attatataaa aaaacatgtg   6300 

tttcaaaccg ttaaaactaa atatttcata cgtgatagtg atatgtttca acatgcgtct   6360 

tcagcgtatt tcaaaaaatt cctgatacta tctgctacta ccctctccct cctctctctc   6420 

catctcatcc atgcacacat gcatttattt tagcaagctt caaaatgatt tttctcttaa   6480 

attacttatc caatatatga cccgattaca ccattgtatt cgttttaatt aaatctttac   6540 

aacaagatat cgcatgacta tattttgata aaggaaaaac atatgctact tgttgtttca   6600 

tatgtgatag caatatgttt caacgtgtat cttcaccatg tttcataaaa tatttaaatg   6660 

ttttagttgc tgattttttt taccgtatat aacttaatgt ttcacttatt ggtaaactgc   6720 

aacatttgac catccgattt tttgataggc atcggacgtc cgatgggtag ctttctccag   6780 

acatatgggg tccacgtggg tccccctcat catgtcagcc aaaaccgatc actgtattat   6840 

cgagtgatca aagttaacga ggtattgtga gttgtgtcag ccaaaaccga tcactgtact   6900 

gtggagtgat caaagttaac aaggtattat gagttgagga tgtgctatac cgtatttcgg   6960 

ttcaggggtg aatggtagac tcggcgacaa attgaggaac ctaaagtgaa cttataccat   7020 

aatgaaatga acccgtcggc ccagatcaga tcggagacca atcccctcga ctctgcggcg   7080 

gcggagtaaa cgagcccaag caagcgctcg ccggcggcgg ccatggacga cgaccgtcgg   7140 

cggcgcctct tcctggattc ttcaggtaac gcccggattc agttccctgc gattttggtg   7200 

gggttgcccc attcgattca ttccatgaag atattcccag gtgtcgattt taagggtttc   7260 

gtgtcaattg cgcggcagat tcgtgttcta gtgcgttcaa ttatgttttc taggtgttca   7320 

tccttcttgc atgtttaatc tggttaaaat actggcacat gaaatgcaca gagggttcac   7380 

acttgcatag tacatctgtg cagcaatgca tctgctcttg cttgcaatgg cctacgatgg   7440 

gagttgtcag aatttcttca gctaaacaat agtagtagat tacaacaaag ttcaaacgct   7500 

gcatcatctg attgctttag ttattttttc tgaaattcga gaatgcaatc taactcataa   7560 

aagtgaaccc accattagat aataaacaaa tgctatgaga tcattctgca gaacaacgat   7620 

ctcaaaaatg aacagaaagg aaaaacattg tctaaacgca gttcaatagt aaaagggcct   7680 

cttacaacaa tctccaaagc aatcaaaata acagaagaac acttcaggtc cagatggata   7740 

agaaagcgaa tgtttcaggt agtgctagca aagtagcaat aactccataa cgatgaactt   7800 

attggaatgg tcaatggacc tgacaaatgc agaggcatca aacaagattg ctaatgtagg   7860 

gagaaggtaa ctagcactcc tagtccccta cacaatcagc cattttttgg tccatctcac   7920 

tctcaatcca gtgagcttca aagtcccagt gcagaccaac cagccagagt ttcttcaggg   7980 

tccgaagggt ttcaatgcca ggagggacac tctccagccc tgacagagca acaatgtaca   8040 

aaccttcaat gactggaagt gcaccactta taatttttag ctggttgaca tcaggcatgt   8100 

gcttcagcac aagtgtcttc aggcatggga aagccgccgc gccaagaacc aatctgcaac   8160 

atctatatac ggacctctgc aacatgcagc atcttctggt gcatcccgtc acctttccat   8220 

tgagtcttga agtctttgtg caggtccttc aaccagagct tcttcaggga ggcaagggat   8280 

tcaatgcctt gagggacttt atccagcttc cacaatgata caatgtataa accttcaatg   8340 

catggaaggg cgccatccgt gatgtttatc tggttgacat caggcatgtg cattaacaca   8400 

agagtcttca ggtgggggaa cgcctctgca tcaagaacca aagttttcga actgtgcacg   8460 

ttgttcagtc ttagataagt gaggtttgac aagtgtgatg cgagcatccc cagtggatct   8520 

tccccaagat tacaccaact tagagctaag tacttgagat gtgtagtgtg gctacgaaat   8580 

atcgggtagt ccaatgtgcc cttggcccat tgccctctga taattaacct gtggagttct   8640 

ttggacatgg gctggagagc ctcaaagcaa agaggttcat tctcatctct tgcagaaaga   8700 

agcaagctag aaagaagcgg catagttgat aatgtagcaa aaatatttcc acaatcagca   8760 

gaacttatgt tgtcaatcca aatacttctt atctgcatta gttccttcag ctgctcggcc   8820 

aagtccttgc tggcttccac agtctcaaga gtctgaagtt cttccaactt agacagatct   8880 

ttgggtgctt gcattccaat gaaatagcga aacactgact gcttctcgtc ttcatatcta   8940 

tcagctagca ggtgccttag cttcttgatc ttagtgattc cacgtggtag cttctctatt   9000 

ttggtttgct tgatgtccag agtttgcagg tttgagagct tctcaataga ctctggtagt   9060 

gagcagagtc ttgtccgcct taagccaatg taacgtaaat taaacaattt acctatgcat   9120 

gctggtactt cagtgatatc tgaatcttgt agctctagga cagtgaggta tttggattca   9180 

gacaaaattg aggataacaa tccaggaggg tgtgtagttg tttcaagtag tgtgcgaaga   9240 

tgtggaaatt tcactgttga tgcacaacct tttccattgt tcaagaataa tgacagacga   9300 

cggacttccc aatcaacctt ttccacagct ccataatcat ttacgcaacc gaacctctcc   9360 

tgtccagcaa ttgagagagc caggttgcgc acaatgtcat gcatcttaca agatctcacc   9420 

ctgccaagct catcatactc gtcaacttca agcatgttcc ggtggatcag ttccatgaga   9480 

tttatttcgg ccacatcttc tggtctattg tgttcggttc tcaccgcaaa accttctgca   9540 

acccagtacc gcacaaggct ctcacgagat atgcgaaaat cttcagggaa caggctgcag   9600 

tacaagaagc agttcttttg gtcagctggt aatgcatggt agcttagttt cagaattgcc   9660 

ttgacatcat catttttggc cagctcactc cgaagctggt tgtacatttg ttgccaggca   9720 

tgctcagttt gtagctttgt ggacatcagg acacccatgg taacaagtgc taggggcagc   9780 

cccttacact tacttactat ggaggcagcc acattctcaa ggtccagcgg gcacctatgg   9840 

tcctttctgt tgtaaaatgc ccttctgcag aaaaggttga atgcatcaat ttcacccaaa   9900 

gcctgtatct tgagatggca ttcagaggga gcaagaactg ccacatgttc catccgtgtc   9960 

gtgatgataa tgcgacttgc ttggggattc ttaagcttgc cctgtatttc gaagtacacg  10020 

ttctggtccc agacatcatc tagcacaatc aaacatgatg tactgttttc agtccttctg  10080 

tttaattctt ctgtcaaatc ttgaacgccc attttgttga ttagatcttc cttagattct  10140 

gatgattctt gttccatgcg tatgagctca ctgactagct gcctacaaag actaaggatc  10200 

gtccaagtct gtgacacagt gatccaggca tgaactggga acttgatctt ttcacgttca  10260 

tatacgtcta aggccagggt ggtttttccc agtccaccca taccagacac tgttattact  10320 

ttgtgacctg gttcttcaga gtacagtaat tcaagcaacc ttttcctgtt gtattcaatc  10380 

cccacaggat cgccacattc aagcaacttc cttcttcctt gagattgcgg tgtttcgatg  10440 

tcagtgggag ttcttggaat gagctgaact gtaggtaacc attccgtttg ctgtctttta  10500 

acctgttcaa tatcaccctt tatcttcatt acctcactag caacttcact gaaaacacct  10560 

gcataatgta ctcttacgaa cctcatcact gatccttctt gctgcagttg acaagcatag  10620 

tatgagtact tgtccattat gtcttcaaca cggtaagcca gcttccgcag ctcgtcgatc  10680 

caacccttta caacattcat gttggtattt gtggaatcta aatcttgtat tacatctttc  10740 

atgacacgca attcccttct gatatactca actttgtctg gaagttccct caagttagtt  10800 

accttcccag acagtttggc tatgacagct ctggtggctt catctcccaa tgcaatactg  10860 

atctttgaga tggcaagcag cacagcttct gccattacct tagtgctgca gaacagaatc  10920 

atgaatcatg gagatagtca cataacgaat tgataagata aaaaaggttg ttgttacagt  10980 

tgtaaaacaa ttgcagctaa gattgttttt tgggcccttg tgggcatttg caagccatat  11040 

atatatatat ttctaatgtt aatcatggtg taccaacaga tataggtaaa ggagctcctc  11100 

attacgtacc agcctcaaca gtaatcttaa ttgtaagggt aatgttctat ggcaattgtt  11160 

tcataactct gcaatgtgac caactgtgta acttaggtcc tgtttggggg agcttgtccc  11220 

agctgtaact tttcccaaaa gctgcttctg ctagaagcta ccccaaacag tccacagctt  11280 

ctgagaatct gtagttacag aatctgaaaa atgaactaag aagccagaag ctggagaagc  11340 

tgggtttcag agcttttcca gattctcaga atctagctac caaacagttg cttctcagaa  11400 

tctaaagctc ccccaaatag gcccttaata ggagatcaaa gtaactcata atcagatagt  11460 

ctcatagttt agttgagtgt gttgtttctt gaagtaggtc tctattcagg tttttaatgg  11520 

ttccacagat agattgatca tttagtataa ctcatatgtg cccagctttt taatgcttca  11580 

tacaaaggcc agtatctaat atgtgtgagt atttcatgca ccatcacttc ttccatgttc  11640 

ttaaatgcaa tgaagtatat atgaaacagc ccagatatat ctgaacataa tatcaaacat  11700 

gatcatagtt tgtttctaat cttacttttc ttttaagcag ccatttctaa tgacaactct  11760 

gttttggatt ctgctcttct agtctgttac accatgctta gatgataggt ttcttgtcag  11820 

tagaaaccta cttgtgaatt ctggcattaa gctgctgaac ctactgataa gtacttaaag  11880 

aacatgactg tgactcaatt tctttttaag tgacaaggag cagaccagca atgctcttaa  11940 

tatgaagtag agatgcacac cacatattcc agtgttctct ttctcagcat ggaagtgctg  12000 

aagcgcatgt ggttcgattc ttttgcttat aacaggtaga ggtcaacatt ttacatatcc  12060 

ttttacaaaa cacaccgttt agcaatacgg aaaacacatt aacgaaaaag aaaaaagttg  12120 

tcgttttgag ttgctgaaaa gaactaccct ctaactgtga atataagaga ttataaccct  12180 

tcgatttgtc cacaaataca agggatcgtg gatcctgagg tgagcaaaca acagaaggga  12240 

tgcagcaaca ttttaggccc cctttgattc aaaggaaatt gatagaaatt ttagaggatt  12300 

tcattcctat aggaattttt cttacaaagc cttttgaatt aaaggaatga atcctatgga  12360 

atcctataaa attcctatgg aatgcctctt cccatacaag ttttggagga attttaacaa  12420 

gaggtagaac ctcatgaaaa aatcgttttg agtctttatc tctcatcaaa ttcctgtgtt  12480 

ttttctgtgg tccaatcaaa tggtcattca tacgttattc ctgtgttttg caatcctctt  12540 

ttacacttac attcctgtca gaattctatg tttttcatat tcctccgttt ttttattcat  12600 

gtgattcaaa ggggccctta gctttttctt actttttttt agtttattca atgtgccaat  12660 

cggcctaatc caattagtgc ttccctttat ctgtactttt tcctattcct taatttctat  12720 

taaaaaaaat ataatccctc gtattacgaa cggagggagt accgtttagc actggtgtag  12780 

atctgttgta taggcagggt catggttgat ttgttatgag atgcacttga taatgtagtg  12840 

ataaggggtg cgtggtttca atcccaaggt cccatgttca atcccaacac gcttacaatt  12900 

tattcttata ataaaaacta gcatggtggc ccgcgcagac tgcgcggcta gcaccattat  12960 

gttttttccc atataattgc atatatgttt tctcattata ttattcaaat atattaaaat  13020 

gacaacataa ttttaaattt tacaataact ttacaaaact actaatacat aatattcata  13080 

ttatatttta tatacgtgtt agttattaat tatttttaat atcaaatttt agttatttgt  13140 

aaattatata tatttctata tggactctag actcgtgttt taatatttct tttttttaat  13200 

tccgaatttt ctgtaaattg tatttctata tagactctat gctcttcttc caatattatt  13260 

tatttttatt tctgaatttt tattatttct aattgtattt ctatctggac tctaaactca  13320 

tctttcaata ttctttaatt tttaatttcg aatttcagtt acttttaaat tgtattccta  13380 

tagtgacttt aaactcttct tcccatgttt ttcttaattt taaattttag ttatttataa  13440 

attgtatttt tatactgact ctaaactcta cttttaattt tattatgttt attccaaatt  13500 

ttagttagtt ttaaattcct atatggactc tatactcaac ttctaatatt ccttattttt  13560 

ttatttcgaa tttctatttt ttttcttcat tgaatttcta tatggactct atactctact  13620 

tctaatattc cttattttta attccgaatt tcagttattt cctaatcgta tttctatatg  13680 

gactgtatac tctacttcta atattcctta ttttgaattc cgaatttcag ttatttcata  13740 

attgtatttc tatatggact ctatactcca cttttaatat tccttatttt taattccgaa  13800 

tttcagttat ttcctaattg tatttctata tggactatat actctacttt taatattcct  13860 

tatttttaat tccgaatttc agttatttat ttcctaattg tatttctata tatggactct  13920 

agtctcatct tctaatattc cttatttttt aattctgaat ttcaactatt tctaaattgt  13980 

atttctatat ggactctagt ctcctcttct aagattccat attttttaat tctgaatttc  14040 

agctatttct aaattgtatt tctatatgga ctctgtcttt tctttttccc taattaatgt  14100 

gagaatttat agaccatgag agcaaacata gaggcttctt cttctattcc tttaataata  14160 

taatagatgt ttgcccttca aatctcgttt atctggttga cttgttactg tttctttatt  14220 

tggtcctagt tgtttttgtc ttccttttgt aatccatatt aattctgtac agccgctata  14280 

gtagcactgg atcttttgta aagcaacatt tcaactatat cgcaaattga ttggccatta  14340 

gaaaatttcg ttgggctact catctttcat gctttgttct tggtgaaatg attggtaata  14400 

gtttccacgg gcattcaatt ttagcttaag atgtccttgc agtagatggc caacaataag  14460 

ataataaatg ataaaaatac gggaaacatg taattaacac acagtattta aggtgatgca  14520 

ctgcaaacaa cagtaatcgc taaatgttgc agttgaatca gcactgaaca aaacaacaac  14580 

acaaaggttc tttccccatc tctgaactga gaatgtgctg ctggccttag atatgctcgc  14640 

tcagggtcaa atttcagaac aaatttccca atattttcta gcaaagagac taattagtga  14700 

tccctcctct caacaaggcg aaattcacga aagaaaaagg cagaattttc cagcagacat  14760 

aatcagaaaa gttaaagctg ataacagcta caaactagct agatgataca aagcaagatc  14820 

cagtggaaat caatctaacc tgagctgcag acgatcagag cgtctagaag agcagagctg  14880 

gcgagacgat cagagcatgt gaggtttaag ataggcaacg aagaaaatat aaagcacaaa  14940 

gccactagcc tcaaatctca atcagatcct tgtctgtttc tctgaactag ccgccgacga  15000 

cttgacgcga agtcgacgcg gctaagcatt tgcagtgcca attatcaact ggccaagttg  15060 

tgcgtgtagg acgggagtcc gctgtggaag cttccttttt cctgatctca aaatttatag  15120 

tataccctcc aaaccgcatg cagtggggga tgctggattc tttttaaatg gaccagaaac  15180 

tcgagaaatt attgctcaat agattatttt gcctatagta aaaaggaaaa gaaaaagtaa  15240 

atcagaattg ttcatatcga aaggaataga atatctgtag tccagtatgc aaattagaaa  15300 

agatacagtt ttgattagtt tactgtcctg cagccagctc actggtcagg ctgttcgctg  15360 

catcttggac atatactccc tttgcccaaa atataagaga ttttagacgg atgagacatt  15420 

tttttagtac aaggaatctg gacatgtact agtaagtgtc acatctgttt aaaatccttt  15480 

atatttaagt acgaatggag taggaagaaa catatcgtta tatttgagga cggagggagt  15540 

aggaagaaac ataccgtgtc accttaacag tccttgtact tatgactcag ttgttgagga  15600 

cctagttagc tagtcggcaa ctgcaaaaat ataattccag tctccttatt ctactcgcta  15660 

atgacagctt agagaaagct aacaaactga tttcttatgt tttcatccaa ctaaaacggc  15720 

cggagacctc caagtcgtct tagtataaaa atctctcaag tcaagtttcc tcgatttctt  15780 

ggtcgtcgtc ttcgtccacc ttttggtatg ctcgattttt ttaaaaaaat tatgactctt  15840 

tttgtaaaac ttatttatga ataaatagac tccaaaaatc taattatgga tatggactct  15900 

actcggtgcc ggtgagcttg gcatcgaggt ttcgtgcacc cacgctggag accttggcat  15960 

cgagttagag ggggaggggg agagagtgtc gatgttgtag atcacgacta cggtatttgc  16020 

agagtttggg gatcattcgt atcagggtat aagcgagact aaggtaaaat aaacggagac  16080 

aaggattttc atgtaggttc aggctcctta tctaccaggt aatagctcta ctcctgctaa  16140 

ttgaaaccag tgttgctctt attcatcaga atcacacaag tacaatattt gggataactt  16200 

atctaatcat cgtcaacacg gcggcatgaa ccaccacacg ttgtcgacaa cagggtagtc  16260 

ctcctcctct aatatgaatt gggcgatatc agagatagcg ctagatccct cttgtcagcc  16320 

tctgtggcac cagattggat ctgtttaggt ttatctctta tgttgatgtc tggcggcatg  16380 

tattgatgta tattttgact gttgcctgtc tatttagact cggcttgtct tggtccgtct  16440 

ccccctcttc ttttaggggt cttgtattta tacccataga tgtcccctta tccaaataga  16500 

actagaaaga taaatatgga tacgatccga atagtccttg tagtttccat gtagaactct  16560 

gcttctcctt ccttatctgg aataccttcc gtatgcaaga tttgattccg tataagactt  16620 

ggtatatggt aggtcccgct aagcttaacc caacactatt gggtatgcct tacccataaa  16680 

actgataggg ggtaggcgcc atgcttcttg gtgcggacac cgagttgtcc cgagatggca  16740 

tgggatggca tgagtgtaca acgagcacca agagtctgag acaccatgga atggcacgtg  16800 

tttggcaact tttttgacaa gtagacaagc acgatcgaga cacctaaacg ccttgcggtg  16860 

attgtagtat cgccaaccac ctcaatctag caaaagctag accaagatgg gttttgataa  16920 

actaaaccgg ctagcggagc cgatttagat agaacaatag ataactaccc gtctcgtggg  16980 

taaacggaag gtttacggga caaacctaca aaggatttcg cactctcgta gtgaaggcag  17040 

acgatttatg gcacaaatcg acaaagatgg atgaactaga ctagaactag attgaaatat  17100 

tgaaaaagca atttaattgg ctaagttgga ttgtgtgtag attgtatgct caattgaacc  17160 

ggccttgtcc cttatatagg ggttgatctt gcctcctaca ggtcctcctc cacgtccaac  17220 

tcaggataga attcaaagga aacccgaaat atagcctcct gagtaaggaa tcctgagacc  17280 

tgacgaaaac agactcgggc ttggactctg ccggtctgac cggccacatg ccgctggaca  17340 

gaccggccct caagtagcgg tctgaccgac caacaaacga cggtcagacc ggccctatgg  17400 

aggaaaccgg cggttttccc aaatcttagc aattttcttt aatttgaaca gacaaacgac  17460 

gatgatgagc atggcgcacc tcaaccctcc ctcttctcca tttcaatccc tgccttttta  17520 

tcagttgatt ctaccttatt tttcctctat gtagctccta atgttactac tttctctatt  17580 

tcatattata agactttcta gcattgctcg catatatata tatatatata tatatatata  17640 

tatatatata tatatatggc aacatatcct atgcacacag gccctcacgt gtacacacgg  17700 

tgcacaccaa ctaaaaaatg tcaccaataa atctagaaaa aatcatacac atactttcaa  17760 

ttgtattaca cctagggtta aaatcttaac gtcaaattca ttatatttta gccgtaacaa  17820 

aaaaacaaaa aatctgacag ttttaaggtt gcaattttgt cagaatttta tcttttttgt  17880 

tattctctat gtagaatgaa tttgaagatg cgactttgca cgtagatgta tatatatata  17940 

tatatatata tatatatata tatatatata tatgtgtgtg tgtttagatt tattaacatc  18000 

tatataaatg tgggcaatgc taaaaagtct tataatatga aacagagtga gtaatatttt  18060 

tttctatgga aatcttgaat acccatcccg aaaatcatgt ctctgtcact aatagggcta  18120 

gtggcatttg gccaagcgtt ggtcgggttg gtatgtgcag gagttactag cacgtgtggt  18180 

ggaggttttt ttttttttcc ttgataataa tttcgtaggg ttataatctt ttgtactttt  18240 

tcccagcttt atcaatatga aatttcacac catcttatct tatgtgtggg ccattttgga  18300 

aaaaaaaaac tgagctgcaa ttgtatcgct ttcagtaaca ccagaccacg cgatcatttt  18360 

tactgtgact cggtggttga tgacctatag cttagctagt tggcacaact gtagatccga  18420 

ttgctccata caatccgtct gcttattcta atcactactg gtagctaatg gaacgtaaaa  18480 

cgaggaagtc attgccattt tgattaatta aattttaatt attttaaact taaaaatgga  18540 

tttatttgat attttaaaac aacttgtata taacaagttt tcacacgaaa tataccattt  18600 

aactgtttaa aaaatatgct aacgaaaacc aaggtaaaat ctgtataatc aaagttagaa  18660 

cggggttaga gaaaagccaa taaaacggcc gtggacctga aaagtttcat tagaatacac  18720 

ctctcaagtc agtctcctct gcatcctggt cgtcgccttc gtctacctct cgcctcgccg  18780 

tcgccggaag aggagctaac cggctggaga tcgattgatc caacatgagt gacaatcctc  18840 

caggtatgtg catgctacaa gcttaaccaa tcatccatag gcgaactatt tcacgtttga  18900 

ataacatatt ttctgtaaat tttcttactt tgtgggtgtt gttcatatgc aggctacttc  18960 

gttggtcgcc cattgaacca tgaagaacag caagcttcac ggccggctga ggaacagaac  19020 

gctcaattcc ctggtaggta tacaggatta attagttttc tgcatacatc aatttgctta  19080 

gttttctgca tacatcaatt tgccggatat gatgtagcag atcttgttat aacttgaggt  19140 

tgataagtgc tttgaaaagg gttcttaatt ttcagtcttc tatgcattct tctattacct  19200 

caggctgttt tgtttgctat gtcctatgat agttttcaac ttttcaaatt tcaaacttat  19260 

aaagattaag agaaatcttt atcttctgat tttccttttc tactactaag gctactacaa  19320 

tggcaatccg gtcagaccaa atgatgctaa gggtgcacag aggaatgaac cgggcttctt  19380 

taagaaactg taagctgcaa ttcgtgtaca gaatatcaga tgcttctgtc tgtagttacc  19440 

cattgatttg tttttctctt tgcatgatgc attggctcat tgaatctctg cagcttcggg  19500 

tgcttcactg ccggtcaaaa tgtgaactag atcaacacgg ctgtattcgc aatgttaatc  19560 

gacagttcat caagaaatca gtggaatttt gatggagaag ttatcatttt aggaaataca  19620 

agttttgttt cttccaaagt ttttcttttc ctgcagttac actgttgtga attgtacaat  19680 

catatcccaa gcaaatgaga ttattccgcg ttatccatta gtattttgct tacctgtttg  19740 

gatctatcaa tttactatat tgctactggt ctcattaaaa ggattgtttt atccaagtcg  19800 

tctttgtcag gaaaaggtcc acatgaatat gaaaactttg aactttctct tggatggttc  19860 

agaaattttt ttttgactca atcgcctatt aattacaacg aacaatcatt tgtcattttc  19920 

aacgaaaaag aataataatg tttgcaaacg agagcagcga tcaatgagat gactttgaca  19980 

attgaccgac ttatttgcaa ctgcaagtct tcaagcaatt gaaccaaact gtcatggatt  20040 

ttaatttttc agcgtttgct ttgagatgaa aatgactata aattaactgg aaaagttcta  20100 

agactcttcg ctgacatgga ttgataggta ttctggtatt tggcatgctt gtggtcttca  20160 

ttaattaatc ctggttcagg gtaaataaac ttggacaata atcaattatt atactcattc  20220 

aaatcaaggc ctggtttaat tcctaacttt ttcttcaaac ttccaacttt tccatcacat  20280 

caaaactttt ctacgcacac acactttcaa cttttccatc acatcgttcc aatttcaatc  20340 

aaacttctaa ttttgacgtg aacaaacaca ccccaaatta cacttagaat cttatattcg  20400 

ccaccaccag tccatactat actaatcaag tagacacctt tactttcatc taatttccaa  20460 

gactaacagc caatgcatca accttatgga ctatcatatt gaaacatttt atatcatgtt  20520 

ccttttgcaa tacttattta caaatacaat cctatgaaac ttaattgtag gaatgaaccc  20580 

caatctcagt cacagccaag cccaagctta ggagtgaact ccaacatctt agcaccaaca  20640 

agcaggtcgc ttagttacta ctccctccgt cctaaaatgt aagatttttt agctatgaat  20700 

ctggacacgt atgtgtccag attcatagct aaaaattgct atattttggg atggaggtag  20760 

tatattaatc ttgcttctag catggtgcca ttggtcaact ccaaggattt ttgtgctgag  20820 

atgttagaag ttttagggtc catttgtgcg atcagttttt aagggtttgt tcttaaaata  20880 

agtattgaaa aagaacacaa atgtgtaaaa tcttcagggg ctacttaaaa gaaaaagctt  20940 

tttgcaaaca gtcaaaagtg atttacacaa gtggccagcc attatgtcta caatttaagg  21000 

cctgcgaaaa tcatgcatct ttcacattga ttgatattct ttgtcttcaa aagcatcata  21060 

catttatcat tgatacgtag gtttatgatt catcggacct atatatcagt aataaagtca  21120 

catgcctttg aatgtagaag aggccgatct ctttcacttg cagccaaact aacacggccc  21180 

aaatatctgt aagacaatga agttttccct gtcatgacaa cttacaagat ccagagtatc  21240 

tgtcctaact aaaacggttg ccagtacggt gaaaataaaa aaaacaaaca gtggatgatt  21300 

tgatattctc attgcatgcc atgtttgcaa tttcgtggaa agaaataaca aatagtggat  21360 

gctttgatat tctctatctc atgccatgtt tgcaaattcc tgatactcta gttactgagc  21420 

tggtcttcga gtagtagtgg tcgctggttg gtgatgccac ttgagcaacg acttgggttt  21480 

taggtcgtcg cggccgaaaa aaaatatcaa tctctgcgcg aatcattggc gtaggccagc  21540 

ctgggagaga ggaaggaaca tcttcctgtg cctccttacc ctcttcgtct tcttttccat  21600 

ctcgttgtgt gcgctcagta gcttctcctc ctacgaaacc aaccagctgc cgccggtgac  21660 

cgtcgatccg tcgaccgccg ccgccatgag cagcgatgtt cctggtacgt gtcactctga  21720 

tcactcaaaa gctttcgttt ctcttctttt ttttttttgt ttgtatcaat caatcatgct  21780 

aaagcctaaa ggaattcttg cttctttata tcagtctaag aatttttcgt ttgctgcagg  21840 

gtacttcgtg gggcggccga tgaaccacgc ggagccggcg aaagaacagc agcagggcgc  21900 

cgacgagcag cggcctgctg ccaacgcgca gatccctggt ggtacgtgca acgttgcaag  21960 

ctcgattcga tcaaattttg ggcacaaaag aatcagtttt gcccgatgtt ttgctgaacc  22020 

ttgcttcgtt ttcgttttat gcaatcgttt tttgacacaa aaattgagtc aattttgtct  22080 

ggttggtttg ctattttttt ttttgcttcg ttttcgtttt tggggggaga agactacttc  22140 

gtcgggcgtc cggcaaaccc gcagcagccg ccgtcgcaac ctcagcgggc gcaggagaga  22200 

ccgagcttct tggccaaatg gtactccaat ttgttctttg aaaatcgaac agcaattatt  22260 

tagattgtat tagatttcat atcgattcgt cactctgtgc tttgttttat gagttgtttg  22320 

atgctttgct cttgctgatt tctctgtttt gtttctgcag ctgcccatgc ctcgccggcg  22380 

gcggagccga gagctagacc gacaaattcg attggaaaat tgaagcaaat ttacatggag  22440 

tgataaggct cagatctgtg ttttgtgttg caagttttgc taatcgatgt ttgtagctga  22500 

aggttgcttc tattcattta tataccaatt gttcattcgt atcatcagag tgcgaattcg  22560 

atgaaattgt gaaattgtcc attctaatcc ggcatgcttt ttctccttcc ttgaaatgaa  22620 

tattctactc cattgctggg taatgtcaag aatgagtttg ttgttttatt ccgtaccgat  22680 

gttgattaat tttttcccct ttttgtgaaa aaaatccaaa tctttaagtt cgtctttgat  22740 

aagaaaaaag aaattctttc tttgctagaa aaaatatctt ctgttttagt caaatttgca  22800 

acttgtgtgc atacgttttg gcaaaaaaaa aattgttacg tgacacctaa aaatgtgtaa  22860 

ttagctataa ggcattgcaa agacataaat tagttagagg atatcataaa aacctcgtaa  22920 

ttagctaccg gacatcaaca gccatatttt attatatgtg gtgcagattg agagagaaac  22980 

aacatgaaaa gtactaattt gcccctatct attatctatt atctatctat ctattctgtt  23040 

ctatctatta tatactaaag tccatgaaac ttcctacaaa cgttctcaag ccaccacatg  23100 

gacatcctat aaacgctctc aagccgccat gtggcatgtg gtattttaat aaattaaaaa  23160 

atatcaaaag tttctaaaaa taacccacca ttgattttca cttaaatcag tgggcccatt  23220 

atttatgcca tattagatct gttatagata acacaaaact aattaaatct atacctaata  23280 

aaaaaaattc gtaaggtttc cgtaagaatc acgttgctaa aatcgtttta atccgctcaa  23340 

tggtctggat ggatcctttt cagtctacct caaaactagg ttaatatagg atatgtatta  23400 

actgatataa catgtgatca caagtagtag cttgcctact tggttattgg agaaaatctt  23460 

cattgtggcc accagggttc tattcccacc accctctccc tttaatgcct attataacag  23520 

gctttggccc atttaagttt ctattgtttc ctttttcttt atttgttttt ttcgcttttt  23580 

tcttgggaaa aaattcctcc cgacgcttta tctttttttt ttcctttttt atgcggtaag  23640 

ttaggataat aacaggtagg gaattcacta aaaacaaagt tcaatagaaa aaacacataa  23700 

ataatttagt taaaactttt aaaagaatag ttgaaaattt caaatatgta gttgaaagtt  23760 

ttcaaaattc gagttgaagt ttcgaaatct taagtgaaag tattcaattt tggtataact  23820 

tattttttta taacttttca attattaaag taatttttaa tttttagtaa aaaagaaaag  23880 

aagtaaagta gattgtaata ccggaaacta attacgtaaa aggaaaaaaa gaggtgcgaa  23940 

aacagagaag aggagacatg gtggcaacca actgcgtgag ttttttttca atttttgatc  24000 

tgactccttg cgcaagaggt gcgaaaaaat agagaagaca ctgtggcaac caattgcgtg  24060 

aaaaagaagt ctcgaaacaa aagataataa aaaaaaggga aaataggtcg cgcgcgactg  24120 

tgcgatggat gggctcaaaa cgcgcaccac ttaaattcgc gacgcgtatg cactaattag  24180 

gagtttcgta ttattacttt cactgtctat gggcctctcc taggccagat tgacctaccc  24240 

tacctaaaac ttttacactt attattactc ggaataaatc tactttgtct ccagatctca  24300 

aatcctattt gcgcgcaatt tttttctctc cgccactagc acggaccatg cacatccttt  24360 

tttttttctc tccaccatta gcacagacca tacacattcg atggctgaaa agtcaaaagt  24420 

tttgtacctc tttcttcaac agatatttag tgattctgaa atcttataat gaaccagttt  24480 

ttaatttaaa aattaaacat aattattttt ttcttttcgt catctgcaaa acacgacata  24540 

ttagagtccg caccatctat catccacaca tgagccgtta aacgatccgt ctccacgcga  24600 

gtccatgttg gattttagaa gttatatcag actcgtgcca tgcaagagtt gagagagagc  24660 

gtgtgctatg acaatatgag tattatatca atatgcaatg gtgtttctta ttagtcttga  24720 

ttatcattaa cccaataaac aatttatcta tcttgaaata ttattacata catgttaacc  24780 

gtgtatttat agcatttaac ctttcattat acccgtagcg aagcacgggc attttgctag  24840 

tctatcaaaa gaaacaaact atcctcccac ccctccagcc gtacgtgcgt atatagtacg  24900 

gagtatggac gtacgtttta ctccttctcc caattctttt tttaactaat ttttttaatg  24960 

gaaaaacaac taataattta aaatccatat cacccatatt ttactatgta caaaaactaa  25020 

aatatattat ttgatcatat cgcatcaaaa cagcatccgg tttttaattt atttaaacag  25080 

taattttatt tgtaattaat taagtaaatc aacatctata ttactatttt gctctataaa  25140 

aatttaaata catcatttga acatacgggc aacaaccaaa caacctcgaa acattaaaat  25200 

gttagtgtca tcttaaatca ttctacgcaa taaagattca tcgaacttat cacattttaa  25260 

aactagaaaa aaattcttag aaatttgagc atcattatat actaaaagtc cattacatgg  25320 

cattcctaca aacactccta tactgccacg tggcactttc ctataaaccg gtggacccaa  25380 

cattttaaat cattagatta ttaattttca ccactaaatc ttatcttcca aaaaaaaata  25440 

tgtacgttcc cccgctccga tcacaagttt acataatacg ttttaaaacg aaaaaaaatg  25500 

tgcacatgta tgtacgtaac tccctctctc cccctctaac cctccccttc catatttcct  25560 

attttttttg gctaacacca aatacgtgta gtataaaaat taattagata gctaaataat  25620 

ctcttggtac atatgtttct atataaaaat tataatacgt cacttggatg tatataccct  25680 

taattttcag gggtgaactc agaaaaaaaa aatcgcaaca tcacttggat attatcaggg  25740 

acactacaca tacaaattat ttaattactg agtgatatgt taattaatat gacatgaatt  25800 

atctattatt atatactaaa aatccattag atatcctaca aattctctca agctatcacg  25860 

tggcttccca taaacattcc taaatcacca catggcgctc taatatatct ttatataaaa  25920 

aattttgaga aaaaaacatc ttacccaaac cggtggacct tatttaaaat gttagatcta  25980 

tatcttaaaa ataaaaccta ccgatcgatc aggccgtcaa aatccatatg tataatgcac  26040 

atatccactt ccctcctcac ggatgagacg aacccactgg ctttcgcctc ttttttttct  26100 

tccttacggc aattaagtta accactaaat aaaagaaaat cctaaaaaga atttaataaa  26160 

aatggtgggc tcattacttt ataccattag gcatctaaca acttctacta acttaattat  26220 

atctctcaac atgtatacga ggtctattta cctatataaa tatgtaaagc taaatcaatc  26280 

tacaaacgta caaataaatt cgtaaatcca tatatgaatg aagctttttt taattactat  26340 

gtctgtccta taatgaatcc taaaatttta tagcaattaa ggaagaatga aaaaaatata  26400 

ctaagattcc cctctctaaa taaggctcat taaataagtg gtatgtgcag agttagaaga  26460 

ttgttagagt actgttagat aaaaaaaaaa tgaataatgg atggttggat gggatgagta  26520 

gtattaaaat cggataaaat ttgaatcctt taatttatgg atggaggtag tagaagcaaa  26580 

tagaagtatg tgattatgtc tttaattaga taaagaagtc atattaccat atttttaata  26640 

ggaaatttct taaattaata tatcctaaaa tctataaatg catctttagt atacaagaaa  26700 

aagtattact taaaagttta aattaagatg ctaatttttt aaaaaagaaa cacatatagt  26760 

ataaatgata gtttcatatg aaccgtatcc attgttgcga cattttttct cataaattta  26820 

agatgacatg attcatgtaa ttttagttta caatttgtaa caatccgttc tctagaacaa  26880 

catatcacag cctatttaac tggcactccc acttacagat atcaccccac ttacactttc  26940 

gttgtcgctt catgtaaaat aatcaacacg aaaatgatat ggttagaggg acaatgcctt  27000 

acaagttagt tgcactcttg cttaactagc aagatggtac tactaaagtg cacacaacac  27060 

aaatcacatc ctttaaataa aacataggcc atatctaatc gaactaggat gtcacagaca  27120 

ccccctcaaa agacctgacg tacccattgg tccaacataa gtatagataa attaaatgcc  27180 

tagaaacatg tcccctcttt gcacgtctgt acgtccagtg atcgaaacta acttttaaaa  27240 

caatcccaaa caaattattg atatacacat atttagaaga gaaaaaatat tttttttaaa  27300 

aaaatcatat acataaacat tcataacaaa atttcaaaca ccactaaata agatacccgc  27360 

gcatcagcgg gggctacctt cctagtatta tatactaaaa gtccattaaa ctccctataa  27420 

acgctctcaa gctgccacgt ggcttcctca aaatactctc acattgccac gtggcactct  27480 

aataaaatag tgaaatccga ccatcgattt tcatttaaat ccgttagatc tatattaaaa  27540 

atcaaaaact cccaccggcc ccacctccgt gcagtactca cgtacgtact gctccctatg  27600 

ttccgttgtc ttttttccct ctgctccttt cttttctttt tccaatcaca gttaaaattg  27660 

aacttatctt tatagaaaag aataccccca caaatagaca ttaaacgcgt taaagtccat  27720 

taaatatcat ataaatattt ctaactgttg tgtggcactc ttaaatcagt tattatatac  27780 

taaaaatcga ttagactttc tagaaatgct ctcatactat catgtggcac cctacagaca  27840 

ctactatacc gccacgtggc gctctaataa atttagaatt ctaaaataaa tctaaccatt  27900 

agttttcatt taatctggtg gacccattat tttttactat ttgatctata ataaaaataa  27960 

ccaatccgat ttttcttaaa agacccacat aacccacgta gctgcatgta cgtacttacg  28020 

tacttcatgc acggcaccac atccatcttt tctcttttct tttctttttc gctcacgaca  28080 

ataaaaaccg aattaattat tccaacccat atatattaac tccagcctat atatatatat  28140 

gcaaaaatat atgcacatac cagtaatata ttatatattt ttatatatta tagatattat  28200 

ttagtatgat gggccccaca tccctccttt tctttttttt tcttttcgat tcatatgaca  28260 

taaaaaccaa attaatatta ataattatat actaaaagtc tattagactt tctgcaaacg  28320 

ctcctgaacc gtcatgtggc atctacaaac gctcttaagc cgtcacgtgg cactgtaata  28380 

aattaaaaaa actataaatc ctgagaaaag aatatctaac atccactttc acttaaattg  28440 

atgggcccat tattttaacc gtcggattta atctcatata aacaaagaga tggaaagaaa  28500 

gaccacatac cttccccacc tctcccctaa gtcgttacgt tcgccctctc cgcacgtact  28560 

cccctctctc tcccgcccct ctaagtataa ttcatttttc ctatattagc taacggggga  28620 

aatttgatta aaaaatttca acatttgtaa catctaaatc atatatcctg aaaaataaat  28680 

atctaccctt taattttaat attaaaatta gtggacataa cacttcaagc cattggatta  28740 

gatttaattt ttctcatcct taaaaaaaaa agacgtccat ccttccctcc attttctttt  28800 

aggaaatcct ctatgttttt ttcctcccat tctctcttta tgaaagcttt tgcaacaata  28860 

aattttaaat aagcatactt ctaaatacat attttttgca acagtaaatt ttaaataata  28920 

ctaacttttt aacttttaaa ttgtacgttc aatttttgat ctatttacac attgtgttat  28980 

ttatgattaa aatcacaatt agaatttaag acacatgttg actatatttt aacttgtaaa  29040 

attatattca tttaagtttt tttgagaccc tttacatgtt attcaaacat atatgaacaa  29100 

ttattaaaag aaagtgatat tatatactat ttcatcatat atcacttcac cggcatgcat  29160 

agctaaaaca gatttatgaa cttcaaaaag ttctaaaaat tctgaattat gagaaaaaca  29220 

aaatatagat tataccatag tttgatgcat cacaaaacat gcataactaa ataagattta  29280 

cttaaaaagt aatgagtcat atcctagctg tttgtccacc tatatatcat tccgagctta  29340 

agatagaaat gacctattct gtaccaaatt ctacatgata aggcaataga aattatatgg  29400 

aagtaaagat aaagctaaat ttcctttctg tatacatggt aatataacgg taatgttcag  29460 

cttcagaaca agcaagcaaa agctgcatct gtatttgttc tgtgtatcta tatattgtat  29520 

atgaaaaatc cattaaactt cttagaatac tctcaagccg ccatgtgaga ctcctaccaa  29580 

tgctcctaag ctgacacgtg gtactctaat aaattagaga aaaccttacg aattttgaga  29640 

aaaaagaaaa aacatccaac cctcgatttt catttaattc gacggaccca ctatttttaa  29700 

attattagat tagatttatt aaaaatacat ctcatataat aatatatata cgtatttcca  29760 

tactatacta ctcacggcaa aaaaagaaaa aaagtaatta ccattgaaaa aaagatgggt  29820 

taaccctacc acggtcccac ctaattgcta cgagagaaat gtatatacgt actgttcaca  29880 

aaaaaactga aaaataattc tcacatgtac aatacgcact actatccacc ggattgagaa  29940 

aaaaaatctc ctggacatgt acatactacg caccgtccac ccgtcccaaa taaacttatc  30000 

aataatgtta gatattttct tgagaaacaa agtcaatgca gacgctaaca acgcacgcac  30060 

actcacccct acgaacgcac acatgcacac tctacctcta tgagtacctt cgagagattg  30120 

ggacgacata ttttgagatt gataaagtca ccatgagtga ttcgctgtcg atgggtacgt  30180 

cgtctaccac taaaagaatt tgtcaaatct gggacttgaa aacgagtggg caatttccac  30240 

cacaaggaac ctaaccagtt gagttatgtt taattcaaaa taatgttgga tattaaaaca  30300 

gccataattt ttaaagtaca cttttataat actcctatgc cttttaaacc agtgaaacca  30360 

ttattttaaa tcgttagatc tatcttgcat aaagaaatca agcgtgtatt catggtacat  30420 

cacatttcaa aaatattatt atgcaattat attaacgtta ggttgcgtag aacctcctac  30480 

ccactctaca tgaaatgttt atacatggat tgtctctcaa actatatcaa tatgcatatt  30540 

aggctatata aaatttagtg gagcatgata atatatatgc aataaaaaaa ataaaaacac  30600 

actacttttg ctttacactt acttttactt tcgttgaaat attttcaaaa gaaaataagt  30660 

ctaccttctt ttcaaatgat gaagaagatt ataaataatt gcatatatat atatatatat  30720 

atatatatat ataaagctaa taggttaaaa attataatag caactaatgc taaaaaaaca  30780 

atttacgggg aaattggggt agatgttctc tggttaatat atcgctttca gtgtctcaaa  30840 

cttagcgtat gacgcatgcc cgcgcatttg cgcgggctac cttcctagtt attatatact  30900 

aaaagtccat taaacttcct acaaacgctc tcaagctgcc atgtggcacc ctataaatac  30960 

tcttaagttg ccacgtggca ctttaataaa atagagaaat ctaacaatcg attttcattt  31020 

aaatcgtgga cccattatta ttttagatgg taaaatcctt ctttcaggtt gcaagtacgc  31080 

acggtttcct tttctacgtt gagtagtata tacgtacaca gggtgaaaac gtattttttc  31140 

atcagcgagt agtccacgta cacgaaagat tgttttcggt aattcttttc tacataccgc  31200 

gaaattttct tattcatttg gaggttaggt gggaggcact attttttttc attattagat  31260 

ctaatctaaa ggcctaaaat taatattggg tccatcaatt taattcaaaa attcattaaa  31320 

cttactgcaa acactcccaa gctaccacgt ggcacgctat aaatactttt atggcaccac  31380 

gtggcactaa taaaatagag aaatctgacc atcaattttc atttaaatcg atatacctac  31440 

tattttagat cgttagatcc atcttaaaaa tcgaaaacct cctaccgtat tattttagat  31500 

cattacatct atctcaagat gtgcttctat gctcctcaga aaaaaaaaag cacgaatgtt  31560 

aaagatggtg aatggtctag attaaaaggt gattaacagg ctaaacgtta ttaggaaggg  31620 

caatttcgtc cttgaggtag ttacccatat cccaaacgtt caatcctgat gcagcgccgc  31680 

cccgcctgcc gccgcattcg atcgcaagta caagagaaaa aaagaaggca ttccatgatt  31740 

ccaaaacagc gaatcctcct ctgttccggc tacacatgtg cagcacctca atccaccatt  31800 

tgattggcat ccatgttctt gccaaatcaa aaaatgagat gggggtagag ataagaagca  31860 

tgacaagaaa aatcagaaat gggcgaaggc agggagcacg ccgggacagg cggtgtggcg  31920 

agaggaggaa gaagggggtg gcgcagcaaa agtatacggg cgatgcacgg tggaggaagc  31980 

gagcgcgatc gctgagagtc atcgatttgt aactcctcat cggctgatcg agtatgtgat  32040 

aacttcacag gacaaaactg cccctcccta atgactttta ctctgttaag caacttttaa  32100 

tctaaatcat tcatgagctt taatatccgt gcaggttttt ttagtgagaa gcatagaagc  32160 

acatcccaaa ttaaaattat cttttaggga aaaacccaca aatagatatc atacgcatta  32220 

aaatccatta aatattctat aaatgtttct aaaccattat gtggccctct taaatttgag  32280 

aaacatccca ccattggttt ccacttaaat tgacatacac actattttac acgttatttg  32340 

atcttttatt tttttttcaa aataaatatc ccgaactatc ttcccttcct atccatccct  32400 

gtgggcatta aagtacataa acgctatgct aagctactgc ttgtctcact taaattagag  32460 

aaaatcctaa caaatatgaa aaaaaattat aaaagatatg gccatcggtt ttgacttaaa  32520 

aatcaacaca ttattttaga ttattttagg tcgttagata aagcatttca ttcaaaaaaa  32580 

aaagaaacat cccaaccctc cctccatccc cacatccccg ggcagtgtgc ggtgttacat  32640 

ttcttacttt tctatgtttt tctatcttta tgataattaa aattaatatt atctgtttga  32700 

actatcatat tagaaaagaa cacaaacgaa cctccaccaa tcatgtatag ccagctatcc  32760 

atctgtccct tatgatctgt ttgaactatc ataatttttt aactgaaatc aataatttaa  32820 

taccaatatt ggctatattt acatgctaaa aaaatacatt ttggacccac atccatatca  32880 

aggcctccac caaatacaag aaaatgctaa aatttctcac taaaaaaaat caaaatatcc  32940 

caccataact ttttatgaaa ctggtagacc catcacctat atcccattag acatctaacg  33000 

actgtagcac tcggggccgg aagagaagaa ccttgatact aaaccaagtt tcgataactt  33060 

cttcagcttt gtcatattca tattatgtct atataagttt ttctaacaca atctaaaata  33120 

catgaccgca tattaatatt ccatttatat aagtttttca aacacaatct aaaatatatg  33180 

cccgcgtgaa tacgcgggct accttcctag ttcaattaat cggcggaccc tacaccgtgg  33240 

cgagcgagtg cttcagttca cacgcaccac catctccagg cgtggccgcc ctccgcgatt  33300 

atgaggcgcg agtgccgcaa cgactccagt ggccatggcg atctttcctc gctctttgcc  33360 

ggctccaacg acaactgccc agcgcctccg atggtggctt cgtcggcacc atccgccatg  33420 

tccggccaca agagggtagg tccggcttgg acaggttcat tgaccaccac cccggcagct  33480 

agctggagca caaccacttg ctgctattgc tttttcttgc atctatttat ttggagtagt  33540 

atatattgca atctgaatgc aagctagtaa gtactccctc cgtattttaa cgtatgacgc  33600 

cgttgacttt tcgatcaaca tttgaccatt cgttttattc aaaatttttg tgcaaatata  33660 

aaaatattta tgttatgctt aaagaatatt tgatgacgaa tcaagtcata ataaaataaa  33720 

tgataattac ataaattttt tgaataagac gaatggtcaa acgttgaaca aaaagtcaac  33780 

aacgtcatac attaaaatac agagggagta ttgagtacca aggcgatctc cacagtacat  33840 

gtatgaagca acttaattgg ttgttatgaa atatttgggt gatctcatct atctatctgg  33900 

atagagcagc aataaatctg ggacacgacg gttggtcgtg ccccacacct cttctcgcct  33960 

cacggcgatt ctaacaaggg acgcgatggt tcccaaacca tcgcgtcttc tgttgccgcc  34020 

tctcttcctc ctatatattg taaccattgt tatcaataaa ggatcgctca ttcattctct  34080 

acattcttgt gtgcaattct ctctctcact caatctctct cgctcaatca attctattca  34140 

caacattggt gaactaatat tgtaccaatt aagaaagaga aaattattcc cagcaaaata  34200 

aagcaaagag aaaactatgt tcggatttca gcggaaagta gtttaattat gctagaatta  34260 

ctacatgggg gtaatttttg atgatttatt tgacagctga atgtgagtgt taacctaatg  34320 

tttgattccc ccaatcttgt ctgctggatg cgagaccact tttttttttt aatgaaatga  34380 

ttgagacgac ttgtagcttt aagatatttg ttttgttgga caatctagca accaatcatt  34440 

ttcttctcac ttggtagcaa gttttctgtt gtttgatcag aatcatagtt gtatcacatg  34500 

gaatttgtag ttctgtacca attaatttta agtttttttt aataagataa atggtcaatc  34560 

aaaaattaat ggtgttgtgt attaaacgat ggagatagtt tattacaatt tgaatttatt  34620 

taagttttgc atgctcggta tatgccccat ctctcttttt ttaaaaaaga acaacagata  34680 

ctttacacga tctatcacaa aactacaaaa ttaagaactt atttcacaaa attagagatt  34740 

cagtgtcttc gtttatcaca aaactataga tactttgcac aatatatcac aaaactatag  34800 

atttaagaac ttgttttaaa aattatagat ttaatatctt catttatcac aaaactacaa  34860 

gtttagggtc tccattatca caaaactaca tgttttaaca atgctaaaac ctgtagtttt  34920 

gtgataatgg agacactaaa cctgtagttt tctaataaat gaagatatta atgtatagtt  34980 

ctgtgataaa cgatatacta aatctatagt tttacgaaat aagttctgtg ataaacatag  35040 

acactaaatc tgtagtttta tgaaacgagc tattaaatct gtagttttgt tataaattgt  35100 

gcaaaatacc tatagtttta taaaatttac tctctttttt ttctaaaaaa aatgatcaac  35160 

catcaatgta aggaaccacc tatacatttg tcgacaaatt ttctactaaa aatttgacag  35220 

atgtaattat agtacaatcg tagtgtaatt acacttgtaa cttgtatata attacactgt  35280 

aacttgcatg taactacagt gtaacttgta tgtaagtttc acgtaatttt gaatcgttag  35340 

atctattaca agatttgttc tggtgaggaa gaaaaaaatc acagcacata catatgtgaa  35400 

agaatttatt cccaggacct ctattttact gaaataacat gttaccgaga gattcttaaa  35460 

agttacatat aagttacatt atagttacag tataattaca tgtaagttac agtgtaatta  35520 

cactacgatt gtactgtaat tacatctgac aaatattagg gggagaaatt tgatgacaaa  35580 

tatctagcaa aatcgaatgt gtaatgtacg tacgtacttc cctcccatta cttttctata  35640 

tgtttttttc ttcatgagaa attaattaaa accaaaatta ttttcacagg caataaagcc  35700 

ccacaaatag actttcacct actaggtcta ctaactcttc ctctatcact ttaaacatcc  35760 

tacaaacgct tttaaaccgc tacatagtgc tattaaatta gagaaaatac tataaaatct  35820 

aaaaaaccaa agtatccagc tatcaatttc tacttaaatt gacagatgca ttgttttaga  35880 

ttgatagtat ttttaaatag aaaaatccaa acctctctcc tctccccacc cctatgcgat  35940 

attcaaatcc attaaacatc ttataaatgc ttataagcta ctatgtgaca ttcttaaatc  36000 

ggagaaaatc ttagaatttt gaaaaaaaat aatccgacca tcggttttga tttaaatctg  36060 

tggaaacttt attttacatg cccacttttt tatatatttt ttttgtaaaa catgttaaca  36120 

ttttcaaatc ttgagtcctg atgtagaatc atctagaaac atgtatttgt tataagacat  36180 

ttcagtttag tgatagttca caaaaaaata ctatgaccat tacttcaata tttcatgaga  36240 

gaaaatttag aacatatgcc tttaccctat gccataaatg cattcatgtt ttcgccccaa  36300 

attgcaaaga tcaaagcatt tcatgcatgt ttcatacaat ggaaatctcc caaaaaaata  36360 

ggacataaaa taaattgaaa actgaaaaaa aatgttggta gatttaaaac ccattctaaa  36420 

tagaaaaaat caaacatttt atgaggattg ttagaatgaa aatatataaa acttaaaata  36480 

aaatcaaaca aaaaatgata ttattgaact tcttttggga tgttagatat cattctgggg  36540 

agtcaaaata ccctaaattt tctcatagga accactccat tgacataatg ttttctcgta  36600 

atttcaaaat tgcatgatct caagtaattt tgttttagaa tttattttta tatgttgcaa  36660 

gtgtaattgt aagaaaataa ctagcgttca aagcacacta aataagctta attttagtgt  36720 

acaatatagt aaaaaatatt ttaataaaaa gttagtcata cataaatatt cataaaaaca  36780 

tttcactcac attatataaa gtgcccgcgc atgtgcgaat gccactctta tcatggtgat  36840 

tttgggttat ttttaattgt aatatactac atctgtccca aaatgtaaca atagttgtct  36900 

agatttatag ctaaaaatac ttacatttta ggatagagag agtagttttc agcatttaca  36960 

tttggcttca tttaattttt cgcggtatgt caaacaactg aacacttgaa caggccgcag  37020 

ccgtagccct ggagcagaac acgaccccct gagtagcggt gtggacgcct ggagacggta  37080 

ctccacttca ccgtgtctcc ttaccaataa aatccagaaa ttattaggag acggaaaagc  37140 

cagcgacgac ctgacccaga aagaaataag gaaaaaaaaa agaaaggaaa agaagaagaa  37200 

ccaagctgca ggcagctggt tcaagagctc cgagcgggtc aaagtctcct cctcctctct  37260 

cgtcggcgag ctccttgcga ttgattcatc aggtgcgtgc attccttcac ttgcagaatc  37320 

catggagctt gcgagcgatt agtagtagtt catgctgcag agccgtttcg ccgcggagaa  37380 

tttttgttgt ctctctcgat ttgctcgtgc tcggcgactt tagtatcacc cgaagatcgc  37440 

gaagaactcc tccttctctc gatttcgatc cgcattccgt tgaccgattg gtacgcgagt  37500 

tgactttgca aggattgatt atctccccct ttgggatgaa cacccagtgt cccccccttt  37560 

gcggcgcccg ccaagtgttc gtcggaatgc ccgttcccga ccgcgagtct aggcacgctg  37620 

cgcgccgacg catccggcga agggaggccg ccacgcctcc gtctggtgtg gttccgcggc  37680 

ctgcgcgcgg cagcgttttt tttttttttg gccaaatctt gtccccggtt gtgcacgatc  37740 

acgatctgct ttgctgactg cgttctcatc ctctcttgtt tgatcctgca gggttcagca  37800 

cactgaccgt acagcacctg cgctccagcc ctgttctctg gtcttccagc aggtgagcaa  37860 

gcatataaat cactactcag tatggctgtg tatttgttgt gtgttctgtt ctatggatca  37920 

tttttttgtt cttcatagtt gttagtcgaa tgttccaggt aatgctgcta aacttgctta  37980 

tctaatgtat agtctttctg ctcactgtct tgttgatgaa ccagttattt tctttgaata  38040 

tgtatgaact atgttcagcc cacaagttgc ttcagctgaa gctgtatgta tgttggtgaa  38100 

atgtaataaa tgcatactca aattaaagta aacaactaca tacagaatag ctgtacttca  38160 

tgatgtataa cagtataaca atgtttcttt tactgaccca ggctcccatc ggatggccta  38220 

tccagccaaa gaaaaagcca aaatttgaat tttcaaactt aattttgaca ttgattttga  38280 

gatattttca acgtagtttc ttttacagca ttggctttta agtcaccgag aacacatata  38340 

taaaagtttt acctacaaat taatttttat tctctaataa gccgttttgg cttattacga  38400 

aaaaagccaa acgataaggc cgccaagcag gagagctctt ccgaaagcat agtttgtccg  38460 

gaaaatctcg tagccgattt ccgaactcca acgtaaggtg ccaaaaaaaa tcgttccaag  38520 

taaattaatg aaatataact tagcactggc cttcatatat ggtactgttt accattctga  38580 

tttggaatcc ttctctgtgc ccatgagcaa atcaaataaa gcttgtcatt tatttgctga  38640 

gttatatctt atgagatgcc attaacttct cattaaacgt tttatgagat catagatgct  38700 

tgtggtaaaa gaattactct atggacacgg tgcatgagta ccattatttc ttttctcaca  38760 

gtggaccatt attatccaag tctgaacagt gccacacatt tcatgcagaa accattggag  38820 

ttctgttcaa tgaaagcaca catttctcca ggaaaatagt gataattaaa ggcatcaata  38880 

aataaaaatt ttctttgata tataagttaa attggagact agaaatcgca agccacttgt  38940 

tgttctcttt tgtaacatga tggtgtgtgt tctttcagaa caaatggctg aggcagtgct  39000 

ccttgctgtc aaaaaggttg gcaacgtgtt agcagatgaa gctgccaagg ctgtcattgc  39060 

caaggtgtct gaaaaggtta ctaatctgaa ggagctgcca gagaaggtcg aagaaataag  39120 

gaagcaactg acaatcatga acagtgttat actacagata ggcacctctt acctcactga  39180 

tatagttgta aagaattgga ttgcagaggt gagaaagtta gcctaccatg ttgaggacgt  39240 

aatggacaag tactcatatc atgctattca acttgaggaa gaaggtttct tgaagaagta  39300 

cttcgttaaa ggttctcatt acgtcatggt atttagtgat attgctgagg aggtagtcaa  39360 

gttagagaag caaatccagc aagttataaa gcttaaagag cagtggttgc acccttccca  39420 

gctcaatccc aaccagcttg ctgagagtgg cagaccacgg tctcacgaca acttcccata  39480 

tcttgtcaaa gatgaagatc ttgtggggat tgaagaccac aagagattgc tggctggatg  39540 

gttgtactct gatgagtcag atagagcagt gataacagta tctggtatag gtgggttggg  39600 

aaaaaccaca ttagtcacaa atatttatga gcgtgaaaag gtcaactttg ctgctcatgc  39660 

atggattgtt gtctcccaga cctacaatgt ggaggctcta ttaagaaagc tccttagaaa  39720 

gattgggtct actgaactgt cacttgatag cttgaacaat atggatgcac atgacctgaa  39780 

agaagaaatt aagaaaaaga ttgaagatag caaatgtttg attgtgctgg atgatgtctg  39840 

ggacaaaaaa gtgtactttc agatgcaaga agcattccag aatcttcaag caactcgagt  39900 

catcatcaca actcgagaga atgatgttgc agcccttgct acctcagcac gccgtctcaa  39960 

cctccagcct ttgaatggcg ctgatgcatt tgaactcttc tgtagaaggg ctttctataa  40020 

caagggccac aaatgcccca aggagctaga gaaggttgct aattctatag tggataggtg  40080 

tcatggccta ccactagcaa ttgtaacggt aggaagcctt ctgtcttcaa gaccagcagc  40140 

agaatttgtt tggaataaaa tatacaaaga gcttcggact gagctagcaa acaatgatca  40200 

tgtccgagca attctaaatt tgagctacca tgacctatca ggagacctca gaaattgttt  40260 

cttgtactgt agcttgttcc ctgaagacta cacaatgaca cgggagagcc ttgtgaggtt  40320 

gtgggttgca gaaggctttg tgctaagcaa agaaaagaac acgctagagg atgtcgcaga  40380 

gggaaacctt atggaactga tccaccggaa tatgctggaa gttgtggaca atgatgagat  40440 

tggcagggta aactcctgta agatgcatga cattgtgcgt gtattggctc tttctattgc  40500 

taaagaggag aggtttggtt cagcaaatga tcttggcaca atgttgctta tggataagga  40560 

agttcgtcgc ttgtcaacat gtggatggag tgatgatact gtatcaacag ttaaattcat  40620 

gcgccttcgg accctgatct cactttcgac aacctcattg tcccttgaga tgttatcctc  40680 

aattttgtgt ggatctagct accttacagt tcttgagctg caagactcag agattactga  40740 

agtgccgact tctattggga atatgtttaa tttacgctac attggtttac gacgcaccaa  40800 

agtcaaatca cttccggagt ctattggaaa gttatctaac ctccacacgc ttgacatcaa  40860 

gcaaaccaaa attgagaagc taccacgaag tgttgttaag ataaagaagc taagacacct  40920 

tttagccgat agatacgttg atgagaagca gtcagatttc cggtactttg ttggaatgca  40980 

tgctcctaaa gaactttcca acttgcaaga gctgcagact ctagaaactg tggagtctag  41040 

caaagacctg gccgagcagc tgaagaaatt gatgcaacta agaagtgtgt ggattgacaa  41100 

cataagttct gctgattgtg caaatatttt cgcttcattg tcaagcatgc catttctttc  41160 

cagcttgctt ctttctgcaa aagatgagaa tgaggaactc tgcttcgagg ctctcaggcc  41220 

aaggtcaaca gaactccaca gactgatcat cagagggcaa tgggctaagg gtacacttga  41280 

ttgcccaata tttcacggga acggcacaaa tcttaaatat ctagctctaa gttggtgtca  41340 

tcttggcgaa gatccactag ggatgctcgc ttcaaatttg ccgaacctca cttatttgag  41400 

actgaacaac atgcatagtg caaacatttt ggttctttca acagagtctt tcccccacct  41460 

gaagacactt gtcttaaagc acatgcccaa tgtgaaccag cttaagatca tggatggggc  41520 

gcttccatcc attgaaggtt tgtacgttgt gtcactctca aagctggata tagtccctga  41580 

gggcattgag tcccttcgga ccctgaagaa gctctggctt ctgtacctgc acagggactt  41640 

caaaactcaa tggcacaaga acggaatgca tcacaagatg cagcatgttc cagagattcg  41700 

tgtttagatg cggctgacag gtgccgtttg tagtagtttt ttttttcctc gtctgtttgc  41760 

agctcaggtg ttgatttcca atgagttagc ttttttgcat tcgcggtgcg tctgtacatt  41820 

ttgtatagtt tcatttactt tgatatttat ctatctatct atctatatct attatatact  41880 

aaaagtccat taaacttcct ataaacactc ctaagccgct atgtggcatc ctataaacgc  41940 

tctcgagacg ccacatgtca ctctaacaaa atagaaaaat ttgaccatcg attttcattt  42000 

aaattggtgg acctattaat tttgaccgtt agatttattt ttacattaaa ataaaatccc  42060 

cctacgacgc ctccacaatg tacgtactat ccatcaatct atcagcaacg tatgtacgta  42120 

cgatccctcc gtttccattt tttttcattt ttctatttcc ataataatta aattagaaaa  42180 

atgcatgcct aaaaaatcca tcaatctact agatctattc ttcctctagc acatcctaat  42240 

aagtccatta aacatcatat aaatattacc aaacatctat ttgacaccta aattagagaa  42300 

aatctaaaaa gatataaaac attcgttcat cgatttacat tattttaggt tattatatat  42360 

atctttttct tacgtaaaac atcccaaact cccttcgcgc tcctatatgg cgttaaaacc  42420 

cattaaccat ccttataaat gtttgtaaac cactctgtaa cacttcgtat atagagtaaa  42480 

taataaaaat ttaagaataa aacatataat cattggtttc gacttaaatc gttgggcata  42540 

ccatttaggt tgttatgaga tttgtattta aaaaaagaaa caaacctcct ttcctctctc  42600 

ccccacccaa caatgtcgaa gccttataca ttaaacatcc aacacattat tttagtcatt  42660 

atatcaatct tttatttttt tgaaaaaaaa tatatcaata atttatttaa gaaaaacatc  42720 

tcgcccacct tatccctatg tggtgtgcat cgttcatcct tttctcttat ttttattctt  42780 

ataataattg aaattaaaat tatctttatg ggaaaaaacc acaaatggac ctccacataa  42840 

caggtctagc tagctctccc atgatccctt ttcttctctt tctcatctta ctaacattta  42900 

tgggaacaat ataaataaaa taatataatc ttttaaatca tatattcaac ttatgatttg  42960 

tttgaactat tgtattttct tagtgaaatc aactttaaga tccatattga gtatatttaa  43020 

atgctaacat aaaaattaca ttccggaccc acatccatct tgaggcatcc acttagtaaa  43080 

aaaatgaaaa ttcatcatta taaatcaaaa tatcacatct taatttttaa taaagcctgt  43140 

agacctatta cctgtatcca attagacacg taacaacttt ctatcaactt aattaatttc  43200 

tctcaacatg tatatggggg taatttgcct atacaatttg actttggtgc tttttatcaa  43260 

taaatgatat ttttaggaga taaaattata tataatctat gaagtcacta ataaattaga  43320 

ggaaaaaaat ctttaaatga taacaatttt atgtcataat gtgtactcca tctagcgtta  43380 

attttttata gacaacattt taaaagtaaa aaacatgctc agttgaacat ccaactgata  43440 

gtaccaaaca tgtggattgc accgagaaat cttttttttt tgaggaaatg caccaagaaa  43500 

tcttagcagt gaaacaactc tgaggtggca ttaccaatat agtgaatata gtgagttaat  43560 

tccatatgga attaaagacc atgttcattt atttcttttt ggtaaaactt gctatgctac  43620 

atcgtaaatt cataatattt actgtagaat aatatagaaa tgtgcattta ttatatgacc  43680 

tctattttca tattcttact caattccaga gagataatta gaatagatga ttttacccca  43740 

tgtcaggttg taggcttaac ccacatatat ttataaccca aattgcagat atcaaatcat  43800 

ttcaaagatg cttggtagaa tggaattctc caatttatta aaaatggaca tgaaaagaat  43860 

tcaaaattta tgtaaatgtt ttaaaaaatt gttgggttta aaacccgttc taaatggaaa  43920 

tattcaaata ttttagcagg actaatagaa cgaaaatatc taaaatttcg aatagaatct  43980 

gataaaaatt tggacttttt gagcaaatgt ttggggaaag atatccccat gggtagttga  44040 

aatacccaaa attttttcat aggaactaca tctattgtct cgacataata ttatctcata  44100 

aattaaaaac tgtacgattt taagtaattt tagtttagaa tttatgtgct acaagggtaa  44160 

ttagaagaaa atcataacca acgttgaaag cacattaaat aagttaaata ataatttata  44220 

tatagtaaag taatatttta atacaaagtc acatatatag atattcgtaa taaaatttca  44280 

cacatattaa attaggtgca cgcgcatgtg cgcgggctac ctttctagtt attattatta  44340 

ttatatacta aaagtccatt aaactctcta taaacactct caagctgcca tgtggctacc  44400 

tcaaaacgct ctcatgttgc cacgtggcac tctaataaga aacagaaatc tgaccattaa  44460 

ttttcattta aatcggtggg cccattattt tacatcgtta gatctatatt agaaaaccaa  44520 

aacgtccaca actatggtcc cacatctcct tccgtgtagg taaggtacgt acatgagcgt  44580 

acgtacgtac aagaccgaag aaagacatcc gttttttctt tttcccctct ctttttctct  44640 

ttctcagaaa tactcgtaca aatgcgtaca tttgtcttat ttctggctag ctactttgta  44700 

aaggtgagca aggttaatgc aaatataaat acactgtgat catgtgatag gtaattatat  44760 

atagattcac gtagattatg tgagactaaa ttagctatgt aatatttaat atttaaaaat  44820 

aaagtttaca ccattatata tttacccaat aaataaataa tgtaagatag tttcctaaaa  44880 

gtccattaaa ctccctataa acattctcaa gctgccatgt ggctccctca aaacgctctc  44940 

atattgccac gtggcactct aataaaatag ataaatcatt attttacatc gttagaccta  45000 

tcttaaaaac caaaacctct caccggcccc acatccgtgc agtacgcacg tactgctcgc  45060 

ctgttccgtt ctcctttttt tttccctttg ttcctttctt ttgttttttc aatcacaatt  45120 

aaaattgaac ttatctttat agaaagaata cccccacaaa tgttaaagtc cattaaatat  45180 

catataaatg tttctaatcg ttgcgtggca cttttaaatt agagaaacat cgaatcattg  45240 

gtttccacta aaatcgatgg acacattatt ttacatcatt atttgatatg tattaactaa  45300 

aagtccatga aactttctac aaatagtcct aaatcgccac gtggcatcat agaagtgttc  45360 

ctaagccacc acatgccact ctaacaaata accgttgatt ttcattatat ttgatggacc  45420 

tattgtttac aacattaaat ttttcttaaa taaaaagtta accacccaaa cctaatccac  45480 

ccatcctgta aatagtaagt acgtacttat atctcatata caactaccta ttatatatga  45540 

aaataataat aatatacctc atatattatt attattatta ttattattat tattattatt  45600 

attattatta ttattattat tattattatg ttgaccgtaa catatatgtc acgtgtctgc  45660 

cattctctct actttctatt ttatagctag caattcaagg taaacatgat gagctaattt  45720 

gtcatgattt aatttataat taaacaaatt aatttaagat caataaaatc taaaagttct  45780 

aagtaaaatg caaaacatca tattatcgat ttacacttaa accgagaaaa atattatttt  45840 

gatgattaga ttagatttat taaactaatt aatccctcac tgctgatctc ctccgtaatt  45900 

tatgattaaa aaattcaaaa agttgtgagt aacaggcaaa atatggcacc atcgatttac  45960 

acttatccta ttatttttaa ccattataga tctattaaac tacttaatcc ctctgtccta  46020 

atctcctagg taattacata attataataa ttgattcata ttacaccacc ctcttcctag  46080 

attaacactt cattcttatg tttttatact ttattaggta caaagagata tcttcgatta  46140 

tatattaaaa gtccattaaa cttcgtacaa acgctcctaa attaccatgt ggcattctac  46200 

aaaacgctac taaaccgtta cgtggcgttc taataaaccg gtggacccac tatttgttta  46260 

ataaatcgat aggcccacta tttgtttaat aaatcgatag acccactatt ttcaactatt  46320 

atatttatct ttataaaaaa acattcatca taggaactca taatttccta tgaggaatta  46380 

tccatagcta tgaccaatcg atgtttgcca tcaaataata aattgattat caatttttct  46440 

acaaaagtgg gtagagccat taattatata tggttgtata tgtaatgtct tttataactt  46500 

aagttttccc tcttttccta tggaatctca agagcatatg tcttaggtac cattttttat  46560 

accgtaagtt accaaccata atctccaata ggtaatttta taaataataa ttaaattcgt  46620 

catgcaattc taacaaagaa aattcattaa aaaacacaat tttaaaactt tgcagatatt  46680 

atttcgttgg tataccgcct ttataagttt ctcaaattta tcctacgtat gagacatgcc  46740 

cgcgcgaatg cgcgggctac cttcctagtt gtatgaaaga gcaaatccat tttttttata  46800 

agacctcatt tgcatgtatt gttgccaata tattaatctc tgtgcttgga gatatatgca  46860 

gtggaaatga gatgaaacaa gatagtagga caaatgctat caatgttatt atgcatcaac  46920 

gcaagcatat aataggattt aagcttctgg tcattcatgt atacagtcta gatttttgcc  46980 

tgctcaggag gcagcctgag cgagtgcttg tttggttgca gttgtatgcc tgaggataac  47040 

agtacatatc attctttgat aattacctca ataaacaata tcaagagact tcattaacgt  47100 

gaaaaacaaa tagaaatata ctcctgcgtt ttgtctatat ggttctacat cgaaacttga  47160 

aaataaacaa gagtaaataa atgatgtagg gcagagtccg gcgttggatt ttgtaggcct  47220 

gagccaggcc aggccggcca cccatgaaac gatccaggac atcaaccaaa caagtactac  47280 

gagacaggcg ccagggaaac gacaggtcag gcgaaaacac ttcagttcag gactccaacc  47340 

aaacagtccc ccacatgcct agttgatgtc acatgccaac gtcagtgcct atgataacat  47400 

gacgaccaac tgcctagttt agtactaact aataactctg agcatgtgtt gattgtgaag  47460 

ataacttggt ggaatgcaga attgtacctt tggaaggaat aaatcgatac cagttgggta  47520 

aataaaagaa gttcctgtca agccacccaa taattcaatt atgaagacac aagactccca  47580 

tcgattttga ccttcagctt gcttcctagc gttctgcact ggtcatctag ctcttttctg  47640 

caaccataga tatccagttc ttccagcgaa ggtgggagac ccttttctgg cagcttcctg  47700 

atgccatagc aacacaagat gtccaacctc ttgagggagt gaaggctgtg cagacctgca  47760 

ggaagatctt gaagagagta gcaatgcgta aagcggagct cttgcagggt cgtgaggagc  47820 

tggagcgctc tctcttgctc atccgttagt ctccactctt cgcttctgaa accgtaaatc  47880 

tttaggtatt caagggaagt gaggtgcttg cagaatgacg tggtaaggat agaggtatca  47940 

tcgatgcaca acttttctag tcgcagatgg ccttgccatg acaaattatc caaacatgga  48000 

ggcaatctgg ggcattcgtg tacttgcaaa ctcctgaggc catagaggaa ttgcaagccc  48060 

tccagtacgg cgagtgtttt acaatattta atcgtcaact cttcgagtgc cgtgcatgat  48120 

tgcagctcta gagatatcaa aaattcagag tggtgcacct ctaatttttt taggcaggtg  48180 

agattcattt gaaagcgggg gcacagggtt tcaataaaac agttgttgat gcaaagttcc  48240 

tcaagtgatt gtggaaggag gtaacccatg tgagctctaa ggccctttac ctgcagcagc  48300 

cttaggttgc cgagcgattg caagccttcc agagaattaa gcgattgcaa gccttccaga  48360 

gaattactag taatttgtaa gcgcgcacaa cgaattgtca gctcttggag tgctgtgcag  48420 

gaatgtaact gcagagatgt caaacttacc tctctcatta gaaacagttt tttcaggcgg  48480 

gtgaggttcc ctggaaagca gagttgaagc atttcaaagg gaccatcata ttgtacaata  48540 

agttcttcaa gggatatagg gaggagccat cttctattcg cctgctcaac atttccatca  48600 

ttatgcaata aggaatcgat gagcttgggg cataccgaaa tctctagctg ctcaagggag  48660 

gtaaatccag ccaaaccatc cttgctccca tgaaatgtta aatcagagca ccatttgata  48720 

tatatcttct tcagagagca tatgatattt aacggaaggc gtggaagttt gttttcagcg  48780 

gaaaatccca atgatggagt ctccgtagct gacataagat ttggttgacc acattcttcc  48840 

tctcctatag atagacctgt tatctgctcg cagtcttgta acctcaactc ttgtagggtc  48900 

ttcatgtgtt gtagcaacag agatagccac ttccctgtta ttccacaatt tctaatatcg  48960 

agaagtttaa gacataggag ggtgttgtga tctgcagctg ccatgtcttc acgggtatct  49020 

gatgggacat ttggagcgaa aagttctagg cagttggata tttccaaact cttcaaagac  49080 

ctgagttgtc ttaaactgtc caatgatata gtcgtaagat tttgacaacc acatattacc  49140 

aatccactta agaacctcaa gttacggaac gccataactt tgtcatccaa cgttatcatc  49200 

tgatcagaag attcatccca ttcatccatc caatcatatg aaaatccgat tcttaatgtt  49260 

ccactagatg acccctcgat tgatggaagt gttgaaactc gggtgatgga taatttctcg  49320 

acattaggtg aaggcggaag aggtttgtgc acacgcaaat gagggcaacc atagatggta  49380 

atctccctta gacaggaaaa ccatgacgac tgctcaatct caaattgcgg gtagttctca  49440 

aacaatggaa agacctccag tgcagggcaa ctcttaatct tcaaaacctt taaattgtca  49500 

ttcaagttcc tgatggaagt gcaggagcat gccttcaagc ttatcaattc agttaataca  49560 

agctcctcca ctgatggaat tgagacttct gttgcattcc tcattttgat caacacaagc  49620 

tttctaagta acgttagcct ttctaaagga agtctttgcc atttttcaca tttttctagg  49680 

tgaagtgttt gcagacaggt aagtgaagac ggaaaccaag ttggggaggt agctccatta  49740 

tacccagata tccgtagatg cttgagactg tgatgtggtt caagaccatc aagcacctca  49800 

cgtgctatgc ctggcaaatt ttttaaaact ggggatatat ttgtatcagc catcgtcagt  49860 

ccctccatca gaggttctat gtcactgtca gtttcatttt cagaactcat gtctgtgtca  49920 

tactcatttt cagagctcat gccactgtca tatccatcct ttgcatcctt cgaggacaaa  49980 

tgtagctttt ctaaattatg tttgtctctt agtcttgcac cacaagcttc gattctagtc  50040 

gtaatagttt caagtccaga cacaccgagc tgtacaagtt ggttcaagga ctgtagttgg  50100 

ttcaagccca aagaattatg aacactaaag tcatttaatt cctgaagaga ggtcattttg  50160 

ccaatgctag tgatggacga gaacacttgc tttgctgcta caagatgcct caggctaacg  50220 

aggttatcca tatcattagg tataataaga tcagattctg aaccagcatc aaatacttgg  50280 

agatgataaa acttgccgac agatagaggc aaagctccgt catcaaactt tatatagcga  50340 

atatgggtag gattcaccag attcaataac gaggggtcaa tatcagtaaa tggtgcagag  50400 

atttgcaaga cacgtagatg atgttccttc tggactatat ctttgaagga tttgaggaat  50460 

atatggttat gctgcccaat tagcaccaaa gttctcaaat gtttcactgg tttaactgca  50520 

tttctaattc tttcttcaac cttgccacaa tcaggatctt cttggtgtgt agaatcggtt  50580 

aatattgaca agtgacgtat agttggcaac attttattgc actgtggatt atctatagtt  50640 

gcgtactctg ttctcgaaac catccttgca aaatcatgaa taagcccaca cataacatag  50700 

gatgtcttgt caacttgagt gaactgattt gtctgtgcac ctggctgaaa gaagccggag  50760 

tttaccaaat tagaaaggta ctccctcccg atctcttcca gtctcttact tgaagagtta  50820 

cgatgcacaa aaccttgaga aatccaaata tggatcaact cctgtccaag gaagcaataa  50880 

ccactaggga atattgaaca atacaagaaa cattgttgta aatagtaagg cagctgatca  50940 

tagctaagct tcaaagaagg catgattcct ctacttatat tcagggattt ccaatcttca  51000 

ttcctcagag tgttgctcca gtgatcaatt gtaagatgct ttcttaatat ttgccctgct  51060 

gtttctgctg ccaatgggtt accatttaac ttgtcagcta ttttctgccc aatgatgttt  51120 

agacttggat gtgctttata attttcgtca tcaaatgcgc atgctttaaa aaataaccaa  51180 

aagtcctcat ttgacaaaga atctaactta atcggttcga ctgtccccac ccgttgtgca  51240 

agagacaaaa ttctagttgt cacaagtatc atattgcctt ttgcacgatt tgatttcaat  51300 

ggagctaata gaatgttcca tgtgttatca tccatgctat tccatacgtc atccaaaaca  51360 

agcaggaatt ttttcgtgcg gatgtccata tgccttttca agatctcctg aagtttggca  51420 

aaactactta ttgcattgtg tctttctttt ctttgatgag atacttcatg tctttcttga  51480 

gagacaaaat ctagaatctc catcgtgagc atcactccat cgtagtcttt agatacccaa  51540 

acccatacct gatcaaagtt atgtttcacc attggatcat tgtatacaag ttgagcaaga  51600 

gctgtcttcc caactcctgc aatgcctaca atgggcacta cagttagtcc atcgtaactg  51660 

tcatctgtaa taatcttcag gatggcattc ttctccgcgt ctcttccata aattttgtgt  51720 

gggctaagac ttgacgttcg gatcagggtc gttgttgtac ttgtacgatg atttgagttt  51780 

ccaacaaggt ccgctccatg tagcgtgaga acctcactaa cagccctgat ggcaacttgt  51840 

aacccaccag ttatttgctg tatcctgcta gaaaattcag ccttattcca agggcgtgaa  51900 

tcgactgcat tgttgttcca agggtgtgaa tcgactgcat tgttgtgtgt tgactcatca  51960 

atattcctca tcctttttct gccggaatta atcttcatcc tttttctgct gccggaacca  52020 

ccgagttgat cagtaatggt gatatttgct gtggtgtcag aagtactgca aaattaaaaa  52080 

ggaaaaaaaa aagaaggatc acacaatcgc tgctgacgtg atgaaccatg caagtatgtt  52140 

acattagtta aaaatagtgc cgggtaaaaa caagaagaag aaaagaacat aaatcctacc  52200 

tcgataggtt tgggtagctt gctcgacgct tgttcttaca actgatgcta tggaggtgat  52260 

tacgcaaaac cgacgtccct gtgtgagaac cacactcgag cacagtgtta cgaacacatc  52320 

ttgccttcaa aggctttcca ttttccaatt cagtgatacg taagttctcc catgccccgg  52380 

accggcctgt tttgccacca ctgctactcg aaatatcagt ggtacttttc ggtgtcactg  52440 

cctctgcttg cagtggtgca tgtttatccg cgctttcagg agcgccttgc catgcatctg  52500 

aaccaagaga aagcggaatg aatgcacctc cctgggcaga aactaaaacg gatacatctt  52560 

acatatccta tcttactata aagttataac ccactaactc ctaaagctta acatgcaaag  52620 

atgccacatc atcattcact aacaagttga cacatcatca tctattaaca atcaatacat  52680 

ttaatatcat acaaacatgc tatattatct ataatttaaa atttattaca ttttagagct  52740 

tttaaaataa aggcatgtta aattattatc acacataatt cacataatat ttcaatatat  52800 

atcttcatta tttattataa tatcttatgc acctatgtaa gttcatcctc acttggttaa  52860 

tattattttt ctcttctcta attaaactat tattttggct gtgtacaccc tcgcaaggtg  52920 

tagaggccgg gtttaatata atccattatc taaaaaaaat taagctatta tcacatcaat  52980 

tgattttagt acttatgtaa gtttatgttg ttaagctatc ttacacatta tttttactta  53040 

ttattattat attgaagtcc cgcagcaaca cgcggggttt catctagtta cgtttatatt  53100 

acctccttgg acctggtgct ggagcctgta gtagtcgagg tcgtcgacta ctgcattgtt  53160 

gtgcgttgac tcaccaataa tcctcgtcct ttttctgctg ccggaaccac agagttcaac  53220 

agtaagagcg atattagttc agcacttact tttttaacta tttttaaaga aaaagaaaag  53280 

aagagaacat aaatcctacc tcgattggtc tttacgctta tccgtacaac ggttgctacg  53340 

gaggtgaata tgcaaagccg acgccccatt ttgacacttg agctcagtgt tacagaaact  53400 

acatttgacc ttcacagcct ttccattttc atattcagtg gcaacaaagt acttccatac  53460 

cttggaccat cttttgccac caggcccacc actgcttctc gaaatatcag tggtaaattt  53520 

tggtctcact acctgatctg cttgcactgg tgcatgttta tgcgcgcttt caggagcgcc  53580 

ttgttgccat gcatttgaac caacagacga aagaggtgat gtacatctta catgcgtacg  53640 

gacgcttata ttacctcctt ggacctggtg ctggagcctg tagtagtcga gctcatcgac  53700 

ggcattgtcg gcgtcgtaga gcagctccct gagacgaccg agcgatcggg tcagcttgtt  53760 

cccgattgct ctctgcctaa cggcagcgac caccactttc accctctcca tctctgactt  53820 

aagcttctcg gtggcatcag agagcccaac ctgacgaatc cactcgtcca gcttgtcgct  53880 

ttccaggttc tccaggatgg tctgcgccag ccactcgatc ccgccctcca gcaaagtgac  53940 

ttccacctct gccatcaggt tcggcggaaa actgctagca gttgctgggc aattggcaat  54000 

ggcatgaaat gatggttgta atgattaagg tgctgaaata atggttgaag tgatatataa  54060 

ttgggatgat taagggacta ttattttttg attaagggaa ccggattatc acagacaagc  54120 

ttcctaaact caagtttttt ttttaaaaaa caaatcttca ataaattttt ttaattagaa  54180 

tattttttaa gaacaatttt tcaaatttgt aacaattaat tcattcattt ctgtcctcga  54240 

ataaattgta atgtcatggt gaaggttatg ttgtgatgaa caatttgcaa atatgttcag  54300 

acaagttgaa tttcatgtat atgacttctt cgtagttttt gtacattaca tgttacatat  54360 

aatactctat tgttgcacta atttaaatca agttggcaag aacttgtgct cggaatatgg  54420 

tttagatatt attctcatgt gcatgcattg gttgaggccg cagaagcgtg gttggtgact  54480 

ggatcgggac taaacacaga gggttaaggt ccatatagtc aaggatgtca tatgggatgc  54540 

tcaggctaga gaactacatg ggaggtgtgc gtatatggat aaagaagtta aacttggagg  54600 

aagtccaaat ttggagggat ctgaatccta atttggaaag atagaaaaga gttggaatat  54660 

gacggagtcc tagtcctagt tagattagga actgtacttg gttatgaagg atatgggtat  54720 

ataaacacta gagggagtga ccaaatatga agagaaaaaa aaagggtttc acatgtttgc  54780 

tcttgcatct agagttcagt ttgtgagatc atagaggagt gcttttgtat gcactttgta  54840 

aacactttga tgcaaaggaa tacgtggtaa tctcactatc ttttacattg ttctagttaa  54900 

tttggttttt tttgcttgat tttattttat cttaataaaa ttgtgctaga acaatagtta  54960 

agagttctcc ttttggtctt ttcttttggg tgaatattta ttgtctctag aggcggatcc  55020 

agcatgggga cggcagggtc tcgagtcccc actactggcg cgagtactat gggagccccc  55080 

acaaagcccc cgctaaatct ttttgctata tgtatgcggg aatggggctg tagctttatc  55140 

tagtttatta agaccccccc tactatctct tcctagatct tccactgatt gtcccagatt  55200 

tgttttgttt ttggttccgc taccaatcac cccacctcta gtaggttcgg ttagctgtgt  55260 

ttcaatccta aaagttatat cagagccacg tgtactcttg ttatggccta taggttttca  55320 

accaagctca tagtttttct tggagttgac ttatagttaa ttcttgaaat ctcggaggaa  55380 

atcttacatc atttctcaag gttttgatat ttagcaaaaa gtttcaactg cttatacgtt  55440 

tcctttgggt attattgatg caaacaaagt tgcttcttaa tacaacaatt gcatagctca  55500 

aaatttgatt ttgagtggtg tttctagttc tggttttgat tggatttctc atcttgaaac  55560 

cgtgaatgag ttgtggaaag ttctgagtat cacaaaggct cttttactat caaggaagtg  55620 

tgtaaagtat cttcaatatt cttcaatatg tatacatata catatacata tacatataca  55680 

tatacatata catatacata tgcatatata tatatatata tatatttgca ctcgagctca  55740 

catgcaccca caatctatac cattgatgtg ttccaagact cgtgctgcaa aatgtaccta  55800 

actttgatca aatgaattct tactatagaa agaaaagatt aggttggtac acaacacata  55860 

taataagtat gttgcatttt tttaccaatt ttttttttca gtaacaatca tatatgaaat  55920 

ttggcaaaat ctaaatcaag aggcctctcg ttttagtgct aacgagagac cctatctaga  55980 

tgccttaact gtagtactag tccccatcaa gtaagtagga aatatattcc tatcacctat  56040 

gtttcaaata aaattttttc ttaaaccact catccgatct atgattcgat tacacggttg  56100 

tgttcgtaag aactaaatct ttataacaag atctcatatg attatatttt gatgataaat  56160 

tataaattac ttttatagta tatctaaatt acttttagat ttcactaaat tacttcttag  56220 

acatataaaa gtaatttcag taaagcttaa aagtaattta catatattat agaagtaact  56280 

taagataaaa aggaagtaat tttgtcatga tattaaaatt agatccgtta tggaggtaaa  56340 

aacgtgagtc tatctaaaaa ttaaatttaa tcaacacaaa ttatgaaatt gactaaaaaa  56400 

gataataaaa taaacaactc acaacattat gattgtataa taagtaattt aatcaaatcg  56460 

aaaagtaact tatatatata tatatgataa aagtaactta catatataat aaaagtaatt  56520 

tacaacataa atatttcttc tatcaaaata tagtcatgta agatcttgtt gtaaagattt  56580 

aattgcaaca agcacaatgg tttaatcgga ttataaatcg gataaataat ttaaaagaaa  56640 

aatctataaa acatatatca tttggtgtat tagtatgcaa ccaagtctaa gacaagtctc  56700 

tggttaagac aatatagagt gcggtctcta tgtagtcatg tccatgaaat ttgtgcatgg  56760 

tatttctcta acccttattt ttttataaca tgatatttag tcaatatgag aaaatgttac  56820 

atctattata tcaccaaatt atcatcttgc aaaaatgata tatcctacca tccaaaacta  56880 

cataaacgag gtaattatat aaacaagata atttatataa acaaggtaaa tttgatctga  56940 

taatttgata acctcaatgt tttacatata aaaaaatttt acatcaacaa ggtattttgc  57000 

acttgtaaaa aatattgtat aaagtaaaca tcatgtatgt tacattttgt tagtacctaa  57060 

tgtacctgcc ctaagattcg tgcaacctat atacagggtg tagattgtgg gtgcatgtgt  57120 

gctcgagtgc aaaaaatcca aaatttacat atatgtatat ctatatatat gcatatgtat  57180 

atacatatat gtatatctat atatgtatat gtatatctat atatgtatat atatagatat  57240 

gtatttacat aaacttatat atatatatat atatatatat atatatatat atatatatat  57300 

gcatatgtat acatatacat atacatatac atatacatac ataaatctag tttaaagcaa  57360 

gtttgaactg aatttgaact tgtttttgtt agattttgat tctaggtata tagcatccaa  57420 

acatataatt agttaggtat gtaatcatgg attgtgaact aaagttaaat ttgagttgtt  57480 

ttgttgatag gtataggtat gaatcgaatt cttataacta ggtatatact cacaatttga  57540 

aaaaattgag tgaatttata tatttgatac catggtgtcc gggaaccatg gagccccata  57600 

tgagacaaat atttgaagag gatcacttgc gtttgattat taacaagttt tatcaaaatt  57660 

tgaagtgtca agaacaagaa aagaggtgga ccaaatacat tgattaatta aacattgtaa  57720 

ataataaagc taataaatag cttggaaaag attatctagg caattcatgt aacacccctg  57780 

gcccatttga agccaatagt agttgcgatg ttggccgacg tgggccaata aaatgtgata  57840 

tagaggtggt ggtttaacac caactttgat gttgctgatg gcctgctaag gctttgtgct  57900 

ctaaccatga cacacctgag ttaactcttt tacatgaagc aatcacaaaa atacaaggaa  57960 

ggtactatgc gtatgttcgc acgctcaaca tgtagagccg actaataaga attttgaatg  58020 

cgggcgtttt gtgagaataa acctatgtaa tctcgtggat gttttgccgg ctgcttgcag  58080 

taaggcaatg ttgtatctga actaccgctt cttataatac aattgtatgt aagccttttg  58140 

catattcccc aaaaaaaagg tggggtagtc caatgccgat gatttttttt tagaaatcgt  58200 

agtagctttg aaagcatggt atatgaataa tccgatgatg tattatcccc cttgatctga  58260 

aaagagtggg gactaataat caggttcttc taacactcag ttatatccag attgaaacat  58320 

tattagttct taaaaatttc cagattgaaa cttgaaagtg cacactgcac atatacaggg  58380 

cctgaaacca ttatttccgc cctgagacta agcatttgat tctatctatc tattatacac  58440 

taaaagtctt ttaaactttc tacaaatgct cctagatcgt caaatggcaa tctataaaca  58500 

ctcctaagct actacatggt aaataaaaaa aatctaacct tcaatttgca tttaaattgg  58560 

tggactcatt cttttggacc attagattag atgtaggaac gttcttttct tttccttcta  58620 

ttatatctat catttttctt tctattagtt agaaagcaaa atttaaaaca tttaaacaac  58680 

tatagcattt aaatcatacg tgcatttttg atatgcttat gttgtttaaa taaaacaaat  58740 

ctaaccttca atttgcagtt aaattggtgg actcattttt tttaaccatt agattagatg  58800 

taggaatgtt cttctctttt ccttctatta tatctctcat ttttctttct attagttaga  58860 

aagcaaaatt taaaacagtt aaacaactaa agcatttaaa tcatacatgt attattgata  58920 

tgcttatgtt gttagattat ttatgattaa taaatttata gttaaaaact caaatttact  58980 

gcaagtatgt agtattatgg atgaggtata tatcttatac ttgaaaacgt aacacccaat  59040 

aattatcacc tcccaaaatt ggacccacct aagccttaca accattagat ttatcttaaa  59100 

gaaaaagttt acctcccaaa atcgggctca cctaagcatg tatgtacata cgtaccttat  59160 

tattttttta aaaaagtaca tcctcctttt cacctattcc ttctcctatt tttatgattt  59220 

attagttaga aaagcaaaag ttttgcttta taacatctaa atcatataac taatttttga  59280 

tatgttttaa attgtttatg actaaattta tagttgaaga ataaatttca ctataattca  59340 

actttgaaaa gaaatgatat tttgagttat attttttgac ttttgtgtgc cattcaagct  59400 

aaaaatatag attttatcat cgtatgtaac ttcataattt acattagatc tacaatcaca  59460 

aaagtaaaat gaatataact atgagtaata ttcctaaaat atattagtta gaaaacaaaa  59520 

gtaatgctat aaagtaagca actataacat ctaaattata cgactactat tgatctgttt  59580 

atgattattt tacatttaaa gagccatatt cactataatt aacttttcat atgtcacttt  59640 

gaggttatat tttatgactt ttgcgtgaca ttcaaacaat tatgaaatta tgaaaaagaa  59700 

ttatgtagat tttattgttg tatataattg cacaataatt aaattagatc tataatgata  59760 

taagtaaaat gataaaagga ctaacttgta ctatttgaag aaaatctaat aagtttgtaa  59820 

aagaattagt tcttactctt tcctaaaatt ggaccaacca ttgcatgttc cgttttcata  59880 

acaattttga gaaaattcct tctatacccc agaaagttta gccaatccct tctacgcccc  59940 

cgagttttgt ctactccctt gtatgcccct gaattttggt tttgatccct ttcataccca  60000 

ttccgttagt caacttgtaa tacaacatta tttctgtaaa gattattgct attgaggtgg  60060 

aagaatattt gttagaacaa gatgcacgca tgctttgttg gattctgatc aagcagctga  60120 

aaatagctag cactttatcg ccatgggtga aaggattaat accagtttta ttctgaagat  60180 

taatcatgta catgtacttg aatttaacac tcctctctct acagcttgtt atgtgctata  60240 

tgtagcagtt catgaacaga atctatgtga ttggagaaag aaaaataaat cagcccgaca  60300 

ggtgtgcttt ggttgttctc agtaaatttt tgaatttatt ttaactttcg ttatgtatgg  60360 

aagtaaactg aggcattgat ttcttttctt tcaatgattt atttcttacc aacacagatt  60420 

ccatgttgtc tgttttatgt gtaatcttgg tatgaatttt gtttttctct atttttccac  60480 

ccagggaatg ccagacatga tttaatgcaa attattttct cagtttcaat gctttctgag  60540 

catcgtctgg aactatggga catcatcttg ctaccttgaa ggaattagat ggcaatggtg  60600 

atgtatgaac caatctcttc ccttttttta ccagctattg caataatcag gtgccactga  60660 

tccccatgaa tgatgcatcg tggttatttc atttgaaaag cttggtgcag tgcttcattg  60720 

aaattgcagc aagtagcgtt ggaggtagca atctaaatgt taatctactt tggggctttt  60780 

gacttcagga atcaggagga aagtggagca aaaaaggagg atcatgtcca tgatacatat  60840 

tacaaggtcc ttttccgact atcaattaaa gatctgacat gtaacctttt ctcattttgt  60900 

attgatgcta gcatgacttg tggtctaaga ttattgttca agtaacattt ggaatttgta  60960 

caaaggatta gacactcaag ttgtcacttt ttacaactct ctggttggag catcgacaga  61020 

atgtgattta ctcctctttt attatgttac gatgatgata aggctaatgg gaatcagcaa  61080 

gatgcactcc ttttactaaa tatataatat gaagaggtgt aatacttcta ataaccagat  61140 

ggtttcacta atgtttgctt agcaatactt agaattctgt attaaatgat tttatcattc  61200 

ttttgatatt cctatatgaa tcgaattggt gttgtataaa aactatccaa tgaagtgcac  61260 

taatatatta tggttaagta cagttttcag attatgaagt tattatctaa atcaagaaca  61320 

tgctatttcc gttctggatc gtattttgac gaatattatt ggagtgatga tgtgctgctt  61380 

attccttttt tataggtgta tgaggatgtt ctatacaaat tttattcatc aaacatatta  61440 

tgtttcagaa gctgcagttc taaatttttt aatgtaatca tgtattttgt ataatataat  61500 

atgaagaaaa acatgccttg cacgtgcatg gttactagtt agttagaaaa gcaaaagttt  61560 

tgttttataa catctaaatc atataactaa ttttcgatat gttttaaatt gtttatgact  61620 

aaatttatag ttgaagaata aatttcacta taattcaact ttgaaaagaa atgatatttt  61680 

gagttatatt tttcaagttt tgcgtgccat tcaagctaaa aatatagatt ttatcatcat  61740 

atataacttc ataatttaca ttagatatac aattgtcgga gatatgggcc cgggggtatg  61800 

tggagtaaag gagagctaat tccctttcca gccacgtggc tctgtgagct ggtcccaccc  61860 

acatacctcg tgagtcacta aggcgatggg gagagcctcg ggggtgacgt cacccccctc  61920 

gagctctccc gtcgttttag cccgagtccc tccctcgggg ggaagtgtga gaggggagtc  61980 

caggctgggc ggccataaat gtgcagcgcc ccaaccgtcc ctcgttgcat tcaatgcggc  62040 

gagggcagac gtgcggcgtg cccgaacgac ccctgtcagt cggatgcgac cggtctgtga  62100 

ccagtctatt gccggtcacg gccgattgaa cgggtggtcg tgcccccacg tcgcctctgt  62160 

ctccgcggag tggcggtagg tacgccccgt cacatccgga cgtcgttcga tgcagggctg  62220 

ccgcaagtcc tcactcattt atgagggaat gacagggctg ccccccgtgt caggcgggag  62280 

acggcgctgg gccccactca aggaccaacc gatgcttagc ttccagcaaa aggcacgggt  62340 

tgaaacccgg tggcaggagc gagcagggcc ccctcccctc cctccgatgg aggaggaggg  62400 

tagagacggc gcatgtggta accccttaag ctataaaagg aggaccttgc ccacaaaaag  62460 

gggggggggc ttttggaggg gaaagcaagg ggaaccttgt aagagttcac tgataatccc  62520 

aaacgcagga gtagggtatt acgcttcaga gcggcctgaa cctgggtaat cgaattgtgt  62580 

gctatctaac cggggatcgg agggacgaac acgcgacttc ggagagacga gtctctgccc  62640 

tcggccgaac tcacgaaagg ggggtcacgc gactccccgc gatcgggggt cttccctcga  62700 

cagctggcgc gccaggtagg gggcagttgc gcgtttgaga agaagtcgct tccttccgcc  62760 

ccaagtcgga ccaggcccta gaccgtcatg gtcgaggtcc tggaagcgga ggaagcggtg  62820 

gcgtttaccc ccaccccgtc tgggagtggg gattcgcgcg aaaaccgtga ccctcgtcac  62880 

catcgccatg gctctcgaag tcctccccgc cgcgagcctt cgcggaggga ggatccaacc  62940 

cgttcaagtg gtacggccct ctccccgctc ccaggcggag ggaggtcgca acgcgtcgga  63000 

gcacgtcgcc gtctcgacta cggagacggt ggttcgcccc aaggcgcgct tcaggaggtg  63060 

ggcgcccttc tgcggcatcc cccggtgaac ccggagccgg agacccccgt acggcgctgg  63120 

ctggacgacg tggccaactt ggtcaccgct gcccagcggc agttggccac gggtggccaa  63180 

tccaccgcca caggtacatc aagtgccccg gctacccttt cctcatcggc gaggagaagg  63240 

gcccgtcgat cggccacaac ctcgaggcga tccacggctc caacgacatc ggaggtctcg  63300 

ggaaggcgga ggtgtcacga tgacctctac ggggcgcagg acgctcgggt caacatcgag  63360 

cgacgccggg acgagcgccg ggctacccgc atgggggaag gcgcctcctc atctggagtg  63420 

ccacgctctt cttcatgagg cagccctccc cccacgctca cccctggggg gcaggttgta  63480 

gggctttcgt tgcgagtctc cggaatgtcc ggtggccccc gaagtttcgc cccaacctca  63540 

cggagaagta tgatggcagc atcagcccct ccgagttcct ccaaatctac accacgatca  63600 

tcgtggcggc agggggtgac gaccgggtta tggcgaacta ctttcccatg gcccttaagg  63660 

gtcaggcgcg tggctggttg atgacccagc cccccgactc cattcactcc tgggaggatc  63720 

tgtgccagca gttcgtcacg aacttccagg ggacatatcc ccgccagagg gaagaagcgg  63780 

acctgcatgc tgtgcggcgg aaggacgacg agtccctccg ttcgtatata cagcgcttct  63840 

gccaggtccg ccacaccata ccgtgcattc cagcccacgc agtagtgtat gcattccgga  63900 

acggcgtgcg gcataaccgc atgctggaga agatcgcctc caaggagccc aagaccacca  63960 

ccgagctctt cgagctggcg gacaaggtgg cccggaagga ggaggcgtgg gcctggaact  64020 

ctcctggcac cggtgcggcg gctgcggctg cccccgagtc tgccccccgc tctaagcggc  64080 

gagataggag aggcaagagg aaaccggccc gttccgacga cgagggccat gtccttgcgg  64140 

cagacaggcc cacgcgggcc ccgtgcaaag gaaagattac cggcgataag ccgagctcca  64200 

ccgccccctc tgacgaaggc cggtcggcgg acaagtggtg ttcggtgcac aacacttacc  64260 

gccacagtct cgccgacttg ccgctcggtc aagaacttgg ccgagcggtt ccgaaaggcc  64320 

gatgaggaaa agcggcaggg tcgacgggag ggcaaggctc ccgtgacctc aaccagtgac  64380 

cagcgagagg aggccaagaa caaggccccc gctgacgatg gcggaggtag tgaggatctg  64440 

gatttccaga taccccaagg gaccgtcgcc acattcgatg ggggggcttg cgctcgcact  64500 

tctcgtcgag ggttcaaggc catgaggcgg gaacttctgg ccgctgttcc cacccacgag  64560 

gcgatccgga aggagcgctg gtcggaggta aagctcacct tcgaccaaag cgaccatccg  64620 

acggtactcg ctcggggagg gaagttggcc ctggtggtct ccccgactat ccacaacgtc  64680 

aagatgaagc gtgtgctggt ggacggcggg gccagtctga acatcatctc cccggctgcc  64740 

tttgacgcgc tcaaggcccc ggggatgaag ctccaaccgt cgctaccaat cattggcgtt  64800 

actccgggac acacgtggcc gcttggtcac gtcgagctcc cagtaacctt cggcgactcc  64860 

accaatttcc gcaccgagcg gatcgacttc gatgtggcgg atctcaatct gccctacaac  64920 

gcggtcctgg gcagacccgc gttggtgaag ttcatggccg ccacccatta cgcctacctt  64980 

cagatgaaga tgccaggtcc tgccggtccc atcaccatct ttggtgatgt caaagtcgcc  65040 

ctcgcctgtg cagaacagcg cgcggacaac ctggcggtgg ccacggggcc gcaggccccg  65100 

gaggcccccg cgtcccgcgc ccccaagaag cgcctcacct tggccgacga ggttcccgtc  65160 

aaggagattc cccttggcga tgatccgtcc aaaaccgcta agattggcgg aaccttggac  65220 

gccaaatagg aaggcgcgct cgtctccttc ctgcgggcga attctgacgt tttcgcatgg  65280 

aagccgtcgg atatgcccgg ggtccccagg gaggtgattg agcaccgcct tgccgtgcga  65340 

ctggatgcgc gaccagtccg gcaaaaagtg cggcgtcaag ccccggagcg acaagccttc  65400 

atcagggagg aggtggcgcg gctcctggag gctgatttca tccacgaggt gattcatccg  65460 

gagtggctgg cgaacccggt ggtcgtcccg aaggccaacg gcaagctgcg gatgtgcatc  65520 

gactacacag acctcaataa ggcatgccct aaagatccct tccctctacc acgtatagat  65580 

cagatagtcg actccactgc ggggtgcgtc cttttgtgtt ttctagatgc atactctggg  65640 

taccattaga ttcgcatggc tagggaagat gaagaaaaaa ctgccttcat tactcctgta  65700 

ggcacctttt gttatacaac catgcctttt gggttaaaaa atgccggtcc tacctttcag  65760 

cgcatgactc gaattacttt aagtaatcag atagggcgca atgtagaggc gtatgtcgat  65820 

gacctagtgg taaaaacgcg ccgccaggac acattgctgc aggacctggc cgagactttc  65880 

gatagtctta ggtccacgcg cgtaaagctg aaccccgata agtgtgtgtt cggcgtgccg  65940 

gcgggcaagc ttcttggttt tctagtctct tcccgaggca tagaagcaaa tcccgagaaa  66000 

atacgcgcga tagagaggat gcgcccccca gcaagctcag ggatgtgcaa tgtgtcgctg  66060 

gatgcatggc cgccctgagt cgatttatat caagactggg cgagagagtg ctgcccctat  66120 

tcaagctcct caagcgcccc gggccgtttg tatggacgga ggaagctgag caagccctca  66180 

atcagttgaa agcttacctc acttctcccc ctatcctggt ggccccgggg ccggaggagc  66240 

cattgctaca tctacttggc tgcgaccccc cacgtggtga gtgcccgccc tagtagttga  66300 

acgcgaggag accgagcggg aggtccctcc gactcgtgat ggcccctcgt cccccaaagc  66360 

ccccagcccc cgggaggacc ccgaggcccc cggaggagaa ggcgaggctt tggcaggagg  66420 

ccccgagccc tgtgatccca agataatccg gaatcccacg agggcccccg agcaggcgcg  66480 

ccccggatca tccgcccctg acaacacgaa ccggccccgc cgaacggtgc agcggcccgt  66540 

ctactttgtc agcgaggcgc ttcgggatgc gaaaacccgg tacccgcagg cccagaaaat  66600 

gctttacgcc atattgatgg cctcgaggaa gttgcgccat tacttccaag cacatcgggt  66660 

ttccgtggta acatcgtacc ctctcggcca aatcttgcac aaccgagagg gcaccggacg  66720 

ggtggtaaaa tgggccatcg agctggctga gttcgacctg cacttcgaac cgcggcacgc  66780 

gatcaaaagt caagtcttgg ctgacttcat cgtggaatgg gccccagtgg acgaccctgt  66840 

tccgtccaaa cccccttcct ctcccgaaga gaaagaggac ccaaacgccg acattcgtgg  66900 

cggacactgg attatgcatt tcgacggctc cctcaccctt caaggcgcgg gagctggagt  66960 

cacactaacc tcgccaagcg gagacgtcct caaatacgtc gttcggctcg acttccgagc  67020 

cacgaacaac atggcagaat acgaagggct cctcgtagga ttgagggctg cagccggaat  67080 

gggcatccac cgtctcctgg tccaaggtga cttctagctg gtcgtaaatc aagtctccaa  67140 

agagtatcaa tgcaccgacc ctcaaatgga tgcatatgtc cgcgaagtac ggcgcatgga  67200 

atgccacttc gacggaatcg agctccggca tgtgccccgg cgcgacaaca cgctcgctga  67260 

tgagctgtcg cgtgttgcgt cggtgcgagc cccacttccc ccggggacct ttgaagaaag  67320 

gcttgtccaa ccatcagcac gaccgaaccc ctcgaggggc tccaacgaca tgccctccgc  67380 

cccgactcct gccgacccgc gcccctcgga gcctgagggg gtcgaccccg accctcctcc  67440 

gtgccccccg gggcccgagg gggtcgaccc tgacccccct cgccaagtcg catggatgac  67500 

tgatatccgg gcgtatctcg acggcaatac tcttcctgag gaccacgcag aagctgaaaa  67560 

gcttgcgcgc atctctaagc ggtacgtcct cgtagaaggg accctctacc ggcgtgccgc  67620 

caacgggata ctcttgaagt gtgtttctcg agagcagggc atcgagctca tagccgacac  67680 

ccatcagggc gagtgcgggg cccattctgc ctcacgaact ttagtcggga aagccttccg  67740 

gcaaggcttt tattggccga ctgcattaca agatgcccaa gaatgggtcc agcggtgtaa  67800 

agcatgccag ttccacgcca agcagaacca ccagccggcc caagccttgc aggtcatccc  67860 

cctctcttgg ccttttgcgg tctggggcta gacatccttg gacctttcaa agcggctcga  67920 

ggcgggtatc agcacctgta cgtcgccatc gacaagttca ccaagtggcc cgaggcttac  67980 

cctgtcgtca agatcgacaa gcattctgcc ctcaaattca tcaggggcat cacctctcgg  68040 

ttcggagtgc ccaaccgcat tatcacagac aacggcaccc agttcaccag tgagctgttc  68100 

ggcgattact gtgacgacat gggcatcaag ttatgctttg cctcgcccgc ccaccccaag  68160 

agcaacggcc aagtcgagcg agccaatgcc gaaatcctca aaggcctaaa aaccaagaca  68220 

tacaacgtct tgaagaggca cggggattca tggctcgagg agttgcccgc cgtgttgtgg  68280 

gcaaatcgga ccaccccaag ccgcgccacc ggtgaaacgc cgttttttct ggtgtacggc  68340 

gccgaagcgg tcctaccctc cgagctctcc ctgggatcgc ctcgcgtcac actgtacagc  68400 

gagaccaacc aggatgacct tcgccgcgat gatctcgatt atcttgagga acggagaagg  68460 

cgagcggcct tgcgtgccgc ccgctaccag cagagcctgc gacgctacca tcagcgtaac  68520 

gtccgggccc gatcactgca agttggcgac ctcgtcctac gccgcgttca gtcgcgccta  68580 

gggctgagca agctctcgcc aatgtgggaa ggcccataca aagtgatcgg cgtgccctgg  68640 

ccaggctccg ttcggttaac cacggaggac ggcacagaat tgcctaaccc ctggaatatc  68700 

gaacacctcc gtcgcttcta tccataatat cgagactttt ttgctttctt ggagctcggg  68760 

ccagcccccg cacaacccct cggtttgtgt gcgcctggct gggggctacc actgtgtatc  68820 

cttttttcct cttacaagca atgaattctt atgtactttt acccaaagac cgtttttttc  68880 

ccttcctctg gcttgtcctg gtttaagggg taatctgcgt ttgctctgaa tcctaagtgc  68940 

tgtgaggcgg cctggaaacc ccgaaaggga gcacgaacgc gggccgtgcc cagggttgcg  69000 

ccgaaccccg gaggatcgga agggcctaca cacggccgtc cccgaccccc ggtcgacgcg  69060 

gcctcggtct ggccagtccc gctaggcggc tccctcggag cagtgggttt gcccatcact  69120 

acttaggtgc cctggaccaa acgcggattc accatctcgc tagaacaagc ccgagggggg  69180 

ggatggggtc aaagcggcat ctcgatcacg gactgattat ccccttttcc cctgtttttt  69240 

ttgttgttct ctctgtttca aagacattca gtggaaggag caatgaatag aagaaacgaa  69300 

aggggaaaag gagctaagga agtttcaatt gcaaaacaag gcaggatggc acgacggcct  69360 

aaatacaaga ggtgcccgct acgggcgcac aacaagaggg aattgaaggc gcggatagtc  69420 

acggggtgcc cggccctccg aggccggcgc cgctgacaat gtcgtcccag tcttcgtcgc  69480 

tatcgtcgcc cccgctcccg ctttcttcgt ccgaggccag cccggaggtg aagcgggggg  69540 

ccgatccctc gaagcccgag acaatcgcgt cggctgcctc ccgaacttgc tcccgggccc  69600 

tcgcttcagt tcccagggaa aaatcttcaa gtgcgcgcca cggcatgaag tcggggtcgc  69660 

gcgcttggtg gcttgcgaga accagctcca ccgcggcccg tgccaaagaa gctgacgagg  69720 

actttatggt ctcgccgacc tcctcttcca gtctctccag gcccgccgct agcccgtcca  69780 

accggaacgc gagcgctggt tgtgtgggcg gaagttggct atgctggcgc acgggaacgc  69840 

cgactcggcg cgccgcgcgc tccagccgag cgacggcgtc ggagagctgc ccgggcccga  69900 

gttcgttggt gaggcggagg gccgcaatct ccctagcctg atcttgcacc aggcgcccca  69960 

ggtcggcaag ggtactctga gccttggcga gcgagctcgc caaccccgcg ccgccgggcg  70020 

gcccgccggc tgccaggtgc ttctcccggg cctccagttc agaagccctc gccgttatcg  70080 

ccgcgcgctc ggcgcgagcg ctctccagat gccgggcctc gcgcctagca gcagcctcct  70140 

cgcgcttcgc aagctgcttg ccaagccggc gcaaggctac ctcgcggcgg tttacctcgg  70200 

cttcgcgctc ggcgagtgcg gcgtcccgtt cctggcacac ctcctcccgc agccgtagct  70260 

cttccgcgcg gcggcccgcg gaagcttccg cggcaagagt gatccgatca tgctcagccg  70320 

cggcctcttc acgaaggtga agggaggcct ccgtttccgc cgccgttctc tcgtgggtgg  70380 

ccaaggtgga ctcccgctga tccagcaggc gtgcttgctc ccccagctcc tgggcccgct  70440 

gtgcctgttc ctggccgcgc gcgttttgtt cgcgctggct ccgatcaagg acctcaatcc  70500 

gccgacggat cgtggcttca aactcctgca cggagcgggc acgatcgtcc aaggccttgc  70560 

gttcagcctc gagtgccgca gtccgggcct gcaacgaggc gtcggcctcc gctgctcgcc  70620 

gctcgtgggc agcggctgcg tcgagggtgc cacgcgcatt cctgaccctc tccgctaggt  70680 

cctcggcatg ggcctcgtac tgaaggcgga tatcgcccag cgcttcgtcc agggcgctcg  70740 

aggcgatcag cgccgcctgc cgctcctcct ccgtctcccg catgacggag tccagcacct  70800 

cctcgcgcgc ctagattttg gctaggtggg cttagtgttt tttgcgcccc accctcacca  70860 

tgtcctccac ggcacggcgc ccctcgtcga ctcgcgcgcg gtccgccaca agctgagccc  70920 

attcggcatc cagggtcgtc cgctcttccg ccagggcttg aacttgggta ttgagcccct  70980 

cccggacagt ggagtcggcg gcggcgagca cctgcagaag tggctccatg ctcgccgggg  71040 

atggggaaga aaagcccacg ggtcaccccc gggacgacgg agtgctgctg gaccccccac  71100 

gagacggggg ctgctctcgg ccccccttct gcgaggccag ccccgagggc gccccaaacg  71160 

caagggggag cggctgttct tttcgtcccc cgcttccagt cctcgggtgg attcggcctc  71220 

ggcctcgggc tcagggccgc cctgtcacat cccaaaaatc ctaaatttat aaattgttgt  71280 

ttaattggaa tttttagaaa ttaaattaaa agcctacaag ctaaacctta attttctagg  71340 

aaaattttca acataaaaat gagctaaata aaattttatt aaatactatg cttgctcctc  71400 

tattttctag atttttctgg gaattatttg agcaagggaa gtatttttaa taattgaaac  71460 

aacattttac aaattgtttt attcaaaaaa gttcaaaaag tccccttctt ggtccttggg  71520 

ccgaatccgg cccatctctc ctctcttctc tctctttccc cgcgctcggc ccagctcggc  71580 

ccaagccgcg cccgcgcccg cgcgcccctc tcacccggag gctgacaggt ggggctcacc  71640 

tgtcaggtcg tcttcaacct cccgccgccg ccgcgcccgc gccgaaccct agccgttttt  71700 

cccgcatcga ttccggccaa atccgatgcg atctcttcaa attgattgag gggttttgtt  71760 

cctctcggtc tcctcttcct tttcccccaa gaatcaaagc aaatggttga gttttggatg  71820 

agatttggat tcggtttcga gtttatctcc aaaaataagt ccgaattctt cccgattcga  71880 

ttccatccgt ttgcggttcg atctcttcga tttgagctca tataaatgtt ccccgtgatc  71940 

tcctctctcg tttgccccct ttcctgagtc ctcccgtgcc tcctagcgcc gtcgccgcgt  72000 

gcttttagcc gtcgccgtcg ccggccgtcc ttcggcattg ccgcgccgcc gtctccgtcg  72060 

tcgccgccgg tcgccgccac cgccattagc ttcgccgtga ggaggagaag gccgtccgcc  72120 

cctccgtttg cgtcgccgac caccggagca cccccgacgc cgtcgacccg agccgccgcc  72180 

gccttcttct tcgtcgccgg ccgccgtcgt tcatcgtctc gtgtcggggt gggtaccgtt  72240 

gagttcctct cgtcgccctc tacgcgttgg tgccctccaa tctcgtcgcc gaggtccgta  72300 

gcgccggcga gctcgtcgtc ccgagccggc cgccgtcgct gacgtcaggc tgacgtcaac  72360 

cctagggcag acgtcacctc tgccagggct gacgtcatcc ttttcctttt tccctttttc  72420 

tcgattttta aatagattaa aactttgaaa aatcataact aaataacctg tagatccgtt  72480 

ttaggtggtt caagtttcta aattcttcta aaatcaagat ctacatgtta aaaatatcca  72540 

catgtactgt ttatgcttgt ttttgtactg ttttgttgat tttgtttatt tgctttagtt  72600 

tccgacgttc cggaggagag cgtttccgtt gaggaaggtt ccgaagcgtt tgtggaagcc  72660 

caaggcaagt cacacagatc ccaaacaacc ctttgagcat gttgatcctg tttaaagcta  72720 

ttattttatt tcaacttatg cattattttc gaatgtcatc gggtggtgaa cctttcccag  72780 

ttaattatgg ccgaagttga ctttattttc ctatgggtta taatttgatt agcatgaacc  72840 

ttatatattg gattggttca gctaaatgct atatatctag gtttgcttag ccatgcttag  72900 

aaacattagc taactaaaag ggttaatggt aaactacttc attattttat gttaataatt  72960 

gtggttattt taatggtagc tcacgatggt caattgtgtg ataataatta attgataact  73020 

aaaacctggc taaggtgggt tgtgagcata tggttttgat ggttgtgctc atgacaatta  73080 

aggaccggtt cgcgagctac tgttgtgata catttatcgt gccaaccaca agccagcgtg  73140 

ggcaacggct ttatcttttg tatagcatag ttcattaaag tgcgccagac tgagaagtgg  73200 

cgagaagtcc atgggggtcg ctggggagtc catgcctctg gttgtagagg gggtgattat  73260 

gatccaggta cggtgcactg tggtgaattg tgttatgtga gggataatgt cacaattcct  73320 

ttccgagata ccgtggtggt attgaggcac atggtaacat gatgtggggt tgtgtcttgt  73380 

gggtacagtg gtacacctct gatcagagtt taatctattc gaatagccgt acccgcggtt  73440 

atgggtgagt tgagcaatgt ttttcgtgat tagtctcaca ctactcatta atggtaataa  73500 

tgtgataatt aatttaattc ctggtttgga atggttaatt cctggtttgg agggttaatt  73560 

tgttcagccg gggttggttg atcaaatgtg gttgggccta tgcaacacgg gtgtgttgta  73620 

tggtgttgat ttaatattga ttaattatat aactgtttta ttattctctt aaatatttat  73680 

taaatgctgt tttctgcaaa tgagctatat tatgccatcc tttgttatcc tgtgcacttg  73740 

catatttgct gtgtggcttg ttgagtatgt catatgctca ttcttgcaat attcattcat  73800 

cagaggagga gtacttcagt gaaggtgatg atcttgagaa ttgagcttat tctggttaag  73860 

ttgcctgtgg agtggagttg ccgtcgctgt tccgtcgttt gttttagttt tatctttccg  73920 

ctgcgtagaa tgttttattt tctttgagag gaactatcta cctctgtaat attttaattt  73980 

gcgagtattt aatagttaat tatttgtact ctattatcaa tattgtcatt gtgtgcctcg  74040 

gttgattcct ggacgagggc ttaacacaca tgtaagcgtt tggaattttg gatagaaatt  74100 

ccgggcgtga cacgccccca gcctcgacct caacctcggg ctcacgaccg tccgcaccaa  74160 

ccgatcctgg gtggcgctcc gcatggaccc cagtctcgga gccgcccccg ggaggggcgt  74220 

cgacgccacc gccgcccacg gtaggtcgag tcccggctaa gggtcgctcg ggatcgggcc  74280 

cagtacgtgt cctgtggacc ccaccgcgag gttgcgaaga ccctgtggtc ttggattggc  74340 

caggcccgga ccgctccggt tgtgcggatt tcgtcctccg tgaggggtcc gaccccgagg  74400 

tcccctgaga aggaatatcg ctacaaggga acccagatcg cgttaacaaa agaaaaataa  74460 

aggggaggga acaagaggcc gagctaggta agagcaccga agtgagcgcc agcgtttgta  74520 

cctgcgggga ggacagttga aggtccactt tgggggctcg atgaagctcc ctcggcacgg  74580 

ctccgtttgc cctatcttcc ggagccgttt cttcttccga ccggcctcgg gcccggcagg  74640 

tcgcttgtga cccgccggtg gaaggtctgt cgcgcgctcg gcgcctcctc cacgcggggg  74700 

agatggcggc caagattcgg tcgccttccg cttccccttc gggtcacttg ccgggtcgtc  74760 

tctgggtttg cggcccgagc cgggcgcccg tgagtcgcta ccaccgcctg gaccgcttgg  74820 

ccgcctcccg cccacggacg cgccgccacc accggcgctg gcggcgctac cgctggcgcc  74880 

cccacggcca ggccggcccc tgccggcgcc gacgaccgac atcacggcca agatgctctc  74940 

ccggtcgcgg tcgcagcaga gggggaggat cccatccggg atcagtgttt gctcggcgga  75000 

gtccaggccc agcacccgcc gaatcaccat cttggcgtcc tcctcgcccc agtcccagcg  75060 

ctggcccgca tgcgtgcgca tggggtcgtt ggggccggta tactcccacg cgccacggga  75120 

tcgttcctgg agaggggcga tacggcggtg aaagtagtcg ccgaagacca ttgcccctgt  75180 

gaggcccaag cttcgcaggc ccctgagacg atcccacacc gcgtcatatt cctcgcccag  75240 

ctccgaagcc gccagccatg cggcggatct ctcgggagga ccggcgggaa ctcgaagtcg  75300 

tgggtgatcc ggcagcgcag tgtagaacca gtctttcttc cagtcctccc ttttcttgcg  75360 

gaggtggctc tcgatgtact gccccgccgt gcctggtcgg ggctggaagt aacatccgcc  75420 

caccaccgca ccctatagca gctgcgggac gaagaaggcc tggaacaacc gcatcgtcgg  75480 

tcgcaccctg atgaacatct cgcacaggtg cgcaaagatg ctcagtgtca tcacggcgtt  75540 

gggcgcgaga tgcaaggcat ggatttcgta gaaatcaaga acctcgtgga aaaatcggga  75600 

gaaaggcgga atcaatcctg ccatggcgaa ggacaagagg tgcacggacc gctccggata  75660 

tcgcggccgt ggccgtgact cccccgccct cacgacggcg ccgtccggca taattttgcg  75720 

ggggaggcta agatgtctgt ctgccgagat gcgggaagaa gggagcactg tgtcgccggt  75780 

gtcttgagcc atgatggccg gcggggcagt gacagaaggc gtggcgcgca aagctgcgtg  75840 

gagtggtgag agtgttaggg ttcgagaggc gagaggacga gtcggcggtt agcgaaagga  75900 

aggaggggag gtccctgcct ccactccctt ttaattctcg cctcatccgc gctcgcctcc  75960 

tcgtttcccg ccctcataat tgcccccatg tccgcagttg tctttccatt tcccgcgccc  76020 

gttcaccacg tcgcccgtcg tatccgcgtc ccacctttag tgcgcctatc accggcgcac  76080 

tcgaggtgga atgcgtaacg gctataagcg caagctgagt gaaccgtcac cacaaccgcc  76140 

gtaggaatag cgggcgaggt aatcgaggcg tggtctaacc gatcccctga ttatcgcgtc  76200 

ccaagcatcc tcgtctttag cgcgatcaga ggcgaccgaa ccgccgctat ggctggcccg  76260 

ctaatctggc cgctcggcaa tactccttta aactccccgc cgggcccata accccagcta  76320 

gggaggtcgt gaggcaccat gtcagaccga tcccaggaag cccgcgtctg acatggcgcc  76380 

gggggctact gtcggagata tgggcccggg ggtatgtgga gtaaaggaga gctaattccc  76440 

tttccagcca cgtggctctg cgagctggtc ccacccacat acctcgtgag tcactaaggc  76500 

gatggggaga gcctcggggg tcgacgacat cccctcgggg gtgacgtcac ccccctcggg  76560 

ctctcccgtc gttttagccc gaggccctcc ctcgggggga agtgtgagag gggagtccag  76620 

gctgggcggc cataaatgtg cagcgcccca accgtccctt gctgcattca atgcggcgag  76680 

ggcagacgtg cggcgtgccc gaccgacccc tgtcagtcgg atgcgaccgg tctgtgacca  76740 

gtctattgcc ggtcacggcc gattgaacgg gtggtcgtgc ccccacgtcg cctctgtctc  76800 

cgcggagtgg cggtaggtac gccccgtcac atccggacgt cgttcgatgc agggctgccg  76860 

caagtcctca ctcatttatg agggaatgac agggctaccc cccgtgtcag ccgggagacg  76920 

gtgctgggcc ccactcaagg accaaccgat gcttagcttc cagcaaaagg cacgggttga  76980 

aacccggtgg caggagcgag cagggccccc tcccctccct ccgatggagg gggagggtag  77040 

agacggcgca tgtggtatcc ccttaagcta taaaaggagg accttgccca caaaaagggg  77100 

gggcttttgg aggggaaagc aaggggaacc ttgtaagagt tcactgataa tcccaaacac  77160 

aggagtaggg tattacgctc cagagtggcc tgaacctggg taatcgaatt gtgtgctatc  77220 

taaccgggga tcggagggac gaacacgcga cttcggagag acgagtctct gccctcggcc  77280 

gaactcacga aaggggggtc acgcgactcc ccgcgatcgg gggtcttccc tcgacaacaa  77340 

tcataaaagt aaaatgtcca gtcaaaaaaa tcataaaagt aaaatgaata taactatgag  77400 

taatattcct aaatatatta gttagaaaac aaaagtaatg ctataaagta agcaactata  77460 

acatctaaat tatatgacta ctattgttct gtttgtgact attttatatt taaagagcca  77520 

tattcactat atttaacttt tgatatgtca ctttgaggtt atattttctg acttttgcgt  77580 

gacattcaaa caattatgaa attatgaaaa agaattatat agattttatc gttgtatata  77640 

attgcacaat aattaaatta gatctatcat ggtataagta aaatgataaa aggactaact  77700 

tggactattt gaataaaatc taataagctt gtaaaagaat tagttcttac tctttcctta  77760 

aattggaccg accattgcat gttacgtttt acaattttga gaaaattcct tctatacccc  77820 

tgaaagttta gccaatccct tctacgcccc cgagttttgt ccactccctt gtatgcccct  77880 

gaattttggt tttgatccct ttcgtaccca ttccgttagt ttaccgttgg ttgaatgttt  77940 

aattccaatg aaaaggacct ttttgccctt agacaggaag ggaatctgaa agttgtagac  78000 

tagttgtatt gtcggaagtg tataattttg ttatataaga ctattatatt catggcttta  78060 

ttgtacaagg tattattcat ggcaaagttt atttttacat aatgacataa aaataatatt  78120 

tatttactta ttaaaagagc atatgtagca attttttggt agttcaacat attttctcga  78180 

gtaaatttca caaaactaca ggtattttga ctaaattatc acaaaactac acatttaagg  78240 

agttgtatca caaaactaca catttagcac caaatttatc acaaaactgc agattttagg  78300 

ttaagtatca caaaaatgca tatttaatat taaacttatc acaaaactac aacttttggc  78360 

tataaacatt attaatttat gattaaattg gttctaaacc tgtagtttta tgataattta  78420 

gttactaaac atgtagttcc gtgacacttc atcttaaatg tgtagttttg tgataaattt  78480 

ggtgttaaat gtgtagtttt gtgatacact gagttaaata tgtagttttg tgataattta  78540 

gtcatagtat ctgtagtttt gtgaaattta ctctattttc tcctgttgta tatattatat  78600 

tggaatgctt tccaaaacta gatttatctt taaaaaatgc tacacatact ttattaatat  78660 

atattaattt ttttgtacga caaagttatg aatatgataa tcacacaaca aattttatac  78720 

ttccaacaat atagtttaca gatttctaca tattcctcac atattgaagg gtaaaactga  78780 

cttttttata cctattaaac ggtcaattaa tggcaagggt acggaaggga tccaaatcaa  78840 

aattcagagg tatacaaggg agtgcagaaa atttaggggc acataaggga ttggctaaaa  78900 

ttcaaggata tggaaggaat tttctcagtt tttaaatgct tagatattaa tggccttata  78960 

tctattctgt atcatagaat tatgagtttc ttcgcatatt attgcatata taaggtagtt  79020 

aaaatgttat atttgttact attaaattta aatttttgga cttatgttaa ttaggtattt  79080 

tcttttaaat atatatatat atatatatat atcacgcata tcacgaggaa gcgaggtcta  79140 

cgacatatct ttgttatgta agtatgcaac agcttgcgtc aatctgaacc aattaaaagg  79200 

atgactaact tgatgctaca aataaaacat atttgttaat gataacagtt ctttagaatg  79260 

tgttaaaaaa tccactaaac attcaattaa ataagacaaa acaccttact tgcttttcag  79320 

ttagacaagt tttataaaca gactagatct aactctatac tgaagaaatc atatataact  79380 

atttataggg atgtcttaaa tattacatgt ttcaaaagca aacaaatagt ttaaaaaaaa  79440 

attacctaag cgaagaaaat ttatggagaa atactgcttt tgaaacatga caggtgtcat  79500 

ccggttgata ttccatctat ataagttttt aaacgcaatc tacaatacat gcccgcgcga  79560 

atacgtgggc taccttccta gttttgtttt tctttttttg ataatctacc ttcctagtta  79620 

ttattaaaac atgataaaga aataatcctc caagttcgtt tcgtgaccta gctagaaagc  79680 

tatcatatta ataagaaagc aaataaatat ttggtttcat tttgtaacag tactcagact  79740 

gatcccacac aaattagagt actacaggag gtacgattat atttggaata aaacaaatat  79800 

atccatgtgt aaattgcaat gaaattgtag atagttctac gtaaaacaag tagaagttct  79860 

agcattcgat ataatgtggt cggagttgga gatgcaatag acatacctaa cttgcggtct  79920 

tgggaagact ttggaggatc ggttgcttgg aatgtcctgt gtacaaacca acgtagacca  79980 

taaagaaatg aatgtacgag acgagaaaga gaggtagata catataagag tgattttacg  80040 

gttggacctt gagtacacct gaagatatat atgagatttt gcattataaa atttagatac  80100 

ctcctggtac atgaagtact aagagggagc aaaaatttta cgttataaaa tggtactttg  80160 

aggttcatct ttgaaaatca taaaatttct ccataagttt cagtttgcac atgaaacaca  80220 

attaaaattt aatttattat tataggtata gtcggagaat aagaaaacta caaggcttat  80280 

aaggtccagg aagtgtgtca gataacatgt ttgttgtaat tgagaaatgc ttttgttgtg  80340 

tggtggactg atgggtgtaa acttttttcc ctacctcggt gtttaaatcg aataaaggta  80400 

ttggggcttc caaaacacaa aaaccagtta ttgtgatttg cttccaggaa cctcatgttt  80460 

tagggcaaaa tgtttcaaaa agccccatat ttatgtaaaa tcctcgtatt tcatttttac  80520 

atatgattat ttgtacacaa attcatgtta actcaaagta cacattccgc ttgtctcatt  80580 

tatcttctcc ccccccccca aatcttttat tatatactaa aattccatta aacttcctac  80640 

aaatgctctt aagccgccac gtggcaatcc tacaaactct cctagatcgc cacatggcac  80700 

tatataatct caccgttgat tttcacttaa attggtggtc ccgatatttt agaccattag  80760 

attgcatctg ttattaaaaa ataatacctt cctttcacag gagaaatata taactgttgc  80820 

ctaaaagata aataccttcc tcacgtacgt acgactaaaa gaaaaaaaaa agctaaacca  80880 

ttaattgttt gctgcaagaa aaagaaaaag aagaccacgt gcatgtactt ataagataga  80940 

gaaaaataaa gaaaaaaaag aacgtagtac cgttccaaag aaaaatcgac gttatttcat  81000 

acaatttaca aatttacgca aatatacgta gctctttaaa cattccatct tttaaattat  81060 

tttaaattta tatccaattt gtgatactat tgtattcctt tacttaaaaa gatgtctatg  81120 

atccaaaata catcatagca ccagcacatg ggacccacat gtatataatt gatgttatgt  81180 

tatctatcta ttatccatct attatctatc tatctattat ataataaaag tccattaaac  81240 

ttactacaaa cgctactaag ccgccacata gcaaccctac aaatgctcct aagtctctac  81300 

gtggcgctat aattatttct aaaaaaatca aaagaaggca aaacatctga tttttttaat  81360 

ctattcccga tggacccatt gttgtcaacc attagatcta tttttaaaaa cgatcaatta  81420 

aatttatctc catcaatccc acggacacgt gcatatatac aagcacagca cgtacgtatc  81480 

taagtaacca gctggcctca tgtccctctt tttcttttct ttttctttct aaaataaaaa  81540 

taaataaata caccgttaga aaccattaga tctatcatga aaacctaaca gttaatttta  81600 

tcgctaaaaa tcactaaata cacgtgcaca taagcaccgt atgtaagtac gtagacacgt  81660 

tggcctcaca accctctatg tctgtttttt ttttcattct gaaatccaaa aaaaataaaa  81720 

taaaacaaag ctacatttag ggtttaaaag taaaaataaa tcaagctata agcttccgat  81780 

tataggatag aaaaaacagt atgcaatttg aattccttat tgattcatca ttgtattatc  81840 

ctttggtttc cacaaatatg tcgtagcaat tctgaaggaa aaaaaatcat tttctaccta  81900 

taccatgcaa gaaacacaca aaaaaattta agtccattaa acatcatgca gaatgctcct  81960 

aaaccgctac atggaacttt aataaattag aaaaaatcat ataaaaatta taagaaaaaa  82020 

gaaaaatact tagctatccg ttctaactta aatcggtgga cccattattt ctaaccatta  82080 

aatcaatcct tcaaaacaca aatcccttcc acctcccact ccctcccgta cataatcact  82140 

cctccctctc caacatccat atgtacaaag catatatctt atatacaact caattagatt  82200 

aaaagtaaaa aaaatgacac ataagttgtt tcgtactccc ccgtcccatt ttaagtgcaa  82260 

ccataaaatt tcatgcccaa tgttgatcgt tcatcttatt tggatttttt ttataattag  82320 

tatttttatt attatgagac aataagacat gaatagttac tttatatgta acttaagttt  82380 

ttaatttttt ttaagttttt taaaagacgg acggttaaag ttgatcacgg aaaatcatgg  82440 

ctatacttag aaatgggagt agtaagtaga tttttaagga ataagtttac attaatcact  82500 

gtctttctta taaataatgg aggtacagtt tcaacctttt aatataaatg aatggttacg  82560 

atgctcaaat gtgctttatt gcgcactcat atcaaaatag acaaattatc agtttgaagt  82620 

atatattttt tatatcttta taactaagaa aatacttaga acatgtgacg agttataatg  82680 

cacgcataat gttatgatgc cggactcagt catcatatag aatataatta ttttaatatt  82740 

ttactgccta attaaatatg tcaatgattg ttagaataac taacgctcaa catttaattt  82800 

tgaaaatatc aaacactcat attcaaaaga aaaagatata gtagtataat tttgaacgat  82860 

attaacaaag tgcccataga gtgagctata aattataatc ttggtggttt ataaatctat  82920 

acaatctaga aagtatcata actacttaaa aacattttta ggacaaatat catatattta  82980 

aactattatc aaataacatc ttaagtaaaa gtcgtcgtat atccctacgg caataaaata  83040 

aaaccaagat gtccatgcat gttttattcc ttcacatagc atgtaggcaa tcaagctgct  83100 

aatggaaagt ttgtttggtt atgatttatg cattgataga tgatattttg atctaggtgg  83160 

gttaataaat tttcaattcc catgattttc tacactccat taaaacatcc gttcttttca  83220 

atactctatt ttacacatgt attcctatca tatttttgta cattttctat tctttttttt  83280 

tcaatcatgt gttacaaagg aacctttaat tttttttcac cgagaggcaa aatcataaca  83340 

tttcacaatc ctaataacac aaattatgat ggtttaaata agatgcccgc gcagatgcgt  83400 

gggctacctt cctagttttt cactaaaaaa aataaataat cctaactaat attgatataa  83460 

taatttgtta aatatacgta taaatgatca aactactacg atcgcaaaat gttgaaaatc  83520 

atctatgtac ttaaaaacgt ctcatatata ttttttacaa ttgttataga taaatatatt  83580 

agttaaattg atgatataaa tttttaggtg aggtttaatg aaatattttg cccccaaact  83640 

tgaggtttta tgaaacaaat tataaaatct agggatttgc atcatggatt cctcaaaacc  83700 

tgaagttatg tgaaatttgc tccaacataa atttcgtgag gtttgaggat gtttatcctt  83760 

tgactagtat tttaaggata aactctcatg tgtttgtggg tgacataaac gcttgttata  83820 

tacttattat actatcggca agtataaaca acccatacct gctatcgtca aggttacgct  83880 

catcctctgg ttccatcttt agagttcggt gttgtttggt taaccaatca tacggagaac  83940 

acctttctcc cggacacgct ttcacagagt gcatctccct tttaaagcat tcatatggta  84000 

aacaattatt attgtgaaaa atccctaaat aagatggtaa agaaatatca taaaaaaact  84060 

aaataggatg gcttcctatt tatgagaaca atccacacct gctatcggaa aggttccttg  84120 

tatcttctag ttctctcttt gttgtttggc gtatgtctat ctctattcgg tatcgtttgc  84180 

ttgaagaacc atcttcgtca gagctctgtt tttgtctgtc cagatgatta gcttcctgaa  84240 

cctgactgac ttttccaaga actttgaagg taggaccgta cggatgcttg ccaatggcat  84300 

tcttgcaaac agattcggca gctccccggt cagattcgat agcaccagtg gcaattccaa  84360 

ttcttgcact gatatccgta aggtttaata ggtgctccac gcccaaaagc gcaataccat  84420 

atccctcacc tctatgggca tcgaaaacta gatacagcct ctgaagattg ggcattgccc  84480 

cttcctgaaa ctctattcgc agtttatgac acctgaattc aaagaatatc agagcagaaa  84540 

atgtaccttt tttgaacacg atgccttttg cagtgggttc ctggacatac agtgagagag  84600 

ctgcaagggt acccaattct gtcaggatat ccatgtcgct atccaggaat tccctgatca  84660 

caattttcaa aatacggagt tctcgaaaat gagcaatcca ctcgggaatt tctgaaaaga  84720 

tgcactcaga tggcaacagc tccagtgttt gaacgggagg agaggatgcg ctcgttgaat  84780 

catggaggct agcagtcgtg tgtgaggtac taggatccat actgtgattc ttgatgccat  84840 

cagtaactcc tggttgattt ggcatacctt ggaactggag tggtaagaaa ctgagatgaa  84900 

gaacattcga tggaacaact gcgtcgtttg catttatttc cagtgtctgc aagtgtttaa  84960 

aactctgcat ctgatctggc agtttcactg taacgctaca attgacctgc atatatctca  85020 

atagaaccag ttgataaatt tctgtgaggt ctatcatgtt tccatcttca cacgaaaaat  85080 

caagacatgc aacacgaaga agcttaaact ctttaattga aggcatgcag ttaaatagcc  85140 

caataaatat aaaagaccga atttctgata gcccaatatt aaccggtgta gtagcatatg  85200 

ttgcactgcc gaagtgtagg gacaatcgat gaaccttgta agtaagtctt actgtcgttt  85260 

gagaataatc aattgcagtg acaaaattct cttcctgggc cttgcgtgtg ataaattcat  85320 

gtacaatatg gtgaactgca taggtcaata tgtcagattt atacttgata tccctacatt  85380 

ggatgagtcc cagattgaca agcttattga aataactcat ggcaacttcc atggcatttt  85440 

cccgtgttga cgagcagaca aaatcttggg ctatccattg attcaccaaa tcttccttca  85500 

aaagtatgta gttatccgga tatacactaa gatatagcaa acatgtcttc aaacaacaag  85560 

gaagactgtt gtagcaaagg ttcagtactt gcttcagtat ctcatcagaa gtagcattta  85620 

ccctcaaatt attgcacaag aaattttcta catattgcca gtacttcaat ctatcttcca  85680 

agttctgtac tgtctcatgt tggattgcta gaagactgcc catgatgata attgctagtg  85740 

gtgagccacc acattttctt gcaatctctt gtgtgacttt gtggaattga ccgggatgct  85800 

ctccagagcc aaaagttcta ctgattagca acttcttcga ctcgtcgaca ctaagagctt  85860 

tcatcttgaa tatgtactga gggttataaa cgcaacaagc cagagcaact tcatcaactt  85920 

ttgtggttgt tattattctg ctcccacaat tattcacagg aaaagcatgt ctaacaacat  85980 

cccatacgga tggagcccat aaatcatcaa ttacaataaa gtacctgaca aataatttgg  86040 

tctgtatcag acgtgttttg tcaagcaaaa gagaaaatat ccaagaaaaa tatcatgaca  86100 

atggattttt gttctaaaaa acaaaaagaa gatttgcaaa cctcctgttt tttagatgat  86160 

tcttgacatc gtcgatgagg ttggtcacag cacaagggac gactggttgg agcggccgaa  86220 

cttgagagag tatattcctc agaatcatcc ttatatcagg ctttttggcc gtctgcacaa  86280 

aagcccggca ctcgaatttt ccttcaagtt cacgccatag tagttcggca agcttggtct  86340 

taccgattcc ttcagcaccg agaatgcata acaccttgag attttcatct tcgtcttcag  86400 

ccatccaacc acgcagcttg tttctcgggc catccatgcc aacagggtca acaaccttgc  86460 

tgaacacagt tggaagatga tgatgtacaa ccatgtttgt gggacttgat ccagcatcag  86520 

catcaagatt atagatgctc catcgctcat tcgcctcctt gacaagagtc aagaatcctg  86580 

agatggtgtc atcccaaccc atcttggcac cagcatcagc gttgaccaac aagtcgatgc  86640 

agtcctccat gtcgtagcaa agctcgcgca catccttcat ccagtaaatc accgtgaggg  86700 

atggatctcg cacatttgaa agcttctcca aacgatcttg tatgacgcta agctcagata  86760 

tgagttgatg gatagtcggg ctatcgagct ccttcaactt ctgtagaagg gagcccatgg  86820 

cacccagcga agcgctaatc ggagcttcca ttcttgtttc tgcctgcagt tgatcaaaag  86880 

ggaacacatc atgagctgct atcagccaga acctcatatg gacgaaaatc atgaaatagg  86940 

aggtaattca ttggaaagaa aaaggaacat cattaatcga aaagaaaacc gcagctaacc  87000 

atgagattat gatatgttag gggagacacg gcagtactgc aaaggtacga caggagttat  87060 

ttggagagtg atttctctct tcttcgtttt aagggcaacg aagaacaaca atatatcctg  87120 

ttcctcgctc cgacctttac atgtccaatc ccaacagctc cgataccccc acgcatgccc  87180 

accaggcacc catacaacag attttgttta tactcaagtg gcacaaccct gtctcagcat  87240 

ttttttattt aaattttaaa attaaatctc ctatcatact ttttaaaaag gctactacta  87300 

tgttttagta tattataggg ctgtgttcgt tccagcccat tcccaacacg aacagtatgc  87360 

acggataatg gagtggtcca ttagtgcgtg cttaattaag tatttgttag ggttacgggt  87420 

tagatatacc ctctaccctt cgatacacgt cacatatcga tatggcatgc ccgcgcatat  87480 

acggacgttc tccgtataca ctaaggaaat ccttcacgga ggttgcagag aataagagtt  87540 

caactcggac aggactgggt cgtcaatgta tcgtgtaggg tccgatgtct ccgagttcga  87600 

cttggaaacc gcctgacctg cgatataaaa gggacccctg ggaggacccg agggatcgaa  87660 

tctcagatcc aacacaacca ccacagccta cgaagtcgga gcctgcagga gccaaatcgt  87720 

cgggatagct agtcgaacct actcgattac gttctcgatg gtttcatcga gttccatcgt  87780 

tccccttttg taacctgtga tttccatcat ataatcccat atcaactgga ttagggctat  87840 

tacctgttaa ggggcctgaa ccagtataaa tcttcgtttt ctgtttgttc gatgtcgtat  87900 

tacgtagatc cttgtaccaa cgtaccccaa taccctctat atctggtcta cgggtatcac  87960 

ccgtcgacag tggcgcgcca ggtaggggca cttggtactc aaggttctac tattacgtca  88020 

tccagctccg ttgacaacag catcagcgtc aacctcaacc agggaatccc tgctcaacaa  88080 

tgctggtgtg gactcaagtc ggcgaaatcg tcttcccggt tttcaccacg atgccgatct  88140 

cagacaataa tcagaaacga gaacgcagtg gctacagccc aagacgatcc catgtcgaag  88200 

gatcctcccg ccgaagcgga gaacggaaca tcgactacat ccaaactcga gaagaattct  88260 

actgcggcca aaccttgtcg ttacgacgag aaccacgagc cgacgagaat aacttccgaa  88320 

gcgacaaggt cctggtgtcc tatccacaaa accaggaaac acactttgca agcttgccgg  88380 

gttttcctcg acgtccacgc cgaaattctc gcttgcaaag agcgtggaat tcagcgtatc  88440 

tctccaactc gtgatgtcta ctgtcctatt cacaagacaa agaatcacga cctctcaagc  88500 

tgcagggtct ttctcagcgc cacaaagacg tcatctccta aggtccatca gtcaggcata  88560 

ccccttagag aggaagacaa ggaacaagaa atgctgatct cagatcgatt cgttagcgaa  88620 

atcaacattg gttcccacga accatcaggc ctgcatttac tcgaggacta tggctcatcg  88680 

ccaacgagta cgccacgcga ggtattggct atcgacggga ccagcacatc agcacatgct  88740 

aatgcggaag cgcaaaatca agtgactaca ctggcccagc acatcaggac catcaacgca  88800 

atattgaggg agacccctta cgatcccgtc ctaaatgatg acctcgcaca gtggatggaa  88860 

cgtctacggg agtcggtaac caacctcagc aatgcgttcg aagaggccgc cgccgcagca  88920 

caccaggaac agccaccaag aggcgatgtc gatggcgaaa atcccgaacg tcaggagtca  88980 

ccccttcaag ctacccctcc acctcgcagc accgttgatc tccgcgacca tctcaatggc  89040 

cgccgagagg cacgacgcac gcaagacgac gggaatcgct cccgacatcg cgtctcttca  89100 

cgacatcgcg aggaacgaga gggccgctcg aacgaagacc aagaccgtgc taatcgccac  89160 

aaccgccacg atcatgatga tcgcgaaagg cggatgcaag gtgatactgg tcgaggacac  89220 

cgccataacg acgagaacga cagagatcgg cgccgggaca acaacggagg acgacgacag  89280 

gattctcgag aaccgagccg acgacctcgt aatcccacac cggatccaag cgatccatcg  89340 

tcatcatctt cttcatcttc gtcgtcagac agacatccac gaaagacaca cgatcgccga  89400 

caagccaccg cccccagcgc tgggtgtagg gcttccggcc gttccctccg tgatgtccga  89460 

tggcctgaga gattccgacc cggagcaata gagaagtacg atgggagtac tgacccagaa  89520 

gaattccttc aagtctactc cacggtactc tacgctgctg gagcagacga caacgcgttg  89580 

gcaaattatc tgccaaccgc attaaaaggc tctgcacgtt catggctaat gcatctcccg  89640 

ccctactcga tttcttcgtg ggcagacctg tggcagtagt tcgtcgccaa ctttcaagga  89700 

acttacaagc gtcacgcgat agaagacgac ctacatgcgt tgacacagaa ctcgggtgaa  89760 

tccttgaggg aatatgttcg gcgcttcaac gagtgcagaa atacaatccc cgacatcacc  89820 

gatgcttctg taattcgcgc cttcaagtcc ggtgtccgag atcgctatac tacccaagag  89880 

ttggcgacaa gacgcatcac aactactcgg agactattcg agatcgttga gcgatgcgcc  89940 

cacgtagacg atgcgttgag acgcaagaac gacaaaccga agacgggggg agaaaagaaa  90000 

ctggccatga acgcacccga gtcaagcaag aagaaaaatc gcaagagtgg gaaaaggaaa  90060 

gctcaggcgg aagttctcgc agcagaatac gcgaacccac ccaagcgccc agacccacaa  90120 

gatagcaacg caaagaaagc atggtgcccc atacacaaga tgaacagaca ttctatggaa  90180 

gattgccttg ttttcaaaaa gtcgctcgag aagcacatgg cgcttgaaaa aggcaagcga  90240 

gtacgagtga tcgagaagga tgcggaggcg gctgctcagg aatcggattc agcatatcca  90300 

gactctaacc tccacgtctc tcacattttc ggaggctcca cagcgtactc ctcaaaacga  90360 

gaatacaaga aggtcgaacg cgaagtctgt tcgacatcac agggggctac acccaagatg  90420 

aagtggtctg aacagaagat taaattttca gaagaagacc atcccaatac tgccgtcatc  90480 

ccaggacgct atccgatcgt ggtcgaaccc actattcgga atatcaaggt cgcgcgggtt  90540 

ctcatcgacg gtggcagctc aatcaacctt ctcttcgcca gcactttgga cgcgatggga  90600 

atcccacgaa gcgagttgac acccaccgat caacccttcc atggaattac tccccaatcc  90660 

tcgtccaaac cattgggcaa aattacgttg cctgtgactt ttggccaagc gaacaacttc  90720 

cgaacggagt agatcacctt tgatgtcgct gaattcgata tagcatataa cgccatcatc  90780 

gggagaactg cacttgcgaa gttcatggcc gcatctcact acgcatatca agtgctcaag  90840 

ataccgggac caaaagaaac aatcagtatt caagggaacg ccaagctagc ggtacagtgc  90900 

gacaagcaga acctcgacat ggtcgagcac acgcctagcc cacccgctac aactgagcaa  90960 

cccaagaaag tggccaagac aaacaagacg ccgaagccag acggcgcgat caagattgtt  91020 

ccactctcta gtgccaaccc cgacaagacc gtcaagatcg aggcatcact aagtgagaaa  91080 

taggaattcg cgctcatcac cttcctccgc gacaatgctg acgtgttcgc ttggcagccg  91140 

tccgacatgc cgggggtccc cagggaggtg atcgagcaca aactcatggt gcgacccgat  91200 

gccaagccag taaagcaaag actgcggcga tttgcaccag accgaaaaca ggccatacga  91260 

gaagaactcg ataaacttct caaagctggc tttatcagag aggtacttca tccagagagg  91320 

tactttatct agtttatttt ctggattcta caactttaac ttctcagaat ctgtactaaa  91380 

agcgagcttt tgattttggg aaaagttgca tgtgctataa gctccacaaa caagtcctaa  91440 

aatagctcac acgttaaata taagatgagt tagaccttgt ttggatcgtt tagtctatgg  91500 

actaaaatta gtctctggac taaaaacttt agtgccctac tgtttggatc cg          91552 

 
           
             6  
             69300  
             DNA  
             Oryza sativa  
             
               misc_feature  
               (26297)..(26395)  
               N is any nucleotide  
             
           
            6 

ggatccatcc agaccattga gcggattaaa acgattttag caacgtgatt cttacggaaa     60 

ccttacgaat tttttttatt aggtatagat ttaattagtt ttgtgttatc tataacagat    120 

ctaatatggc ataaataatg ggcccactga tttaagtgaa aatcaatggt gggttatttt    180 

tagaaacttt tgatattttt taatttatta aaataccaca tgccacatgg cggcttgaga    240 

gcgtttatag gatgtccatg tggtggcttg agaacgtttg taggaagttt catggacttt    300 

agtatataat agatagaaca gaatagatag atagataata gataatagat aggggcaaat    360 

tagtactttt catgttgttt ctctctcaat ctgcaccaca tataataaaa tatggctgtt    420 

gatgtccggt agctaattac gaggttttta tgatatcctc taactaattt atgtctttgc    480 

aatgccttat agctaattac acatttttag gtgtcacgta acaatttttt ttttgccaaa    540 

acgtatgcac acaagttgca aatttgacta aaacagaaga tattttttct agcaaagaaa    600 

gaatttcttt tttcttatca aagacgaact taaagatttg gatttttttc acaaaaaggg    660 

gaaaaaatta atcaacatcg gtacggaata aaacaacaaa ctcattcttg acattaccca    720 

gcaatggagt agaatattca tttcaaggaa ggagaaaaag catgccggat tagaatggac    780 

aatttcacaa tttcatcgaa ttcgcactct gatgatacga atgaacaatt ggtatataaa    840 

tgaatagaag caaccttcag ctacaaacat cgattagcaa aacttgcaac acaaaacaca    900 

gatctgagcc ttatcactcc atgtaaattt gcttcaattt tccaatcgaa tttgtcggtc    960 

tagctctcgg ctccgccgcc ggcgaggcat gggcagctgc agaaacaaaa cagagaaatc   1020 

agcaagagca aagcatcaaa caactcataa aacaaagcac agagtgacga atcgatatga   1080 

aatctaatac aatctaaata attgctgttc gattttcaaa gaacaaattg gagtaccatt   1140 

tggccaagaa gctcggtctc tcctgcgccc gctgaggttg cgacggcggc tgctgcgggt   1200 

ttgccggacg cccgacgaag tagtcttctc cccccaaaaa cgaaaacgaa gcaaaaaaaa   1260 

aaatagcaaa ccaaccagac aaaattgact caatttttgt gtcaaaaaac gattgcataa   1320 

aacgaaaacg aagcaaggtt cagcaaaaca tcgggcaaaa ctgattcttt tgtgcccaaa   1380 

atttgatcga atcgagcttg caacgttgca cgtaccacca gggatctgcg cgttggcagc   1440 

aggccgctgc tcgtcggcgc cctgctgctg ttctttcgcc ggctccgcgt ggttcatcgg   1500 

ccgccccacg aagtaccctg cagcaaacga aaaattctta gactgatata aagaagcaag   1560 

aattccttta ggctttagca tgattgattg atacaaacaa aaaaaaaaaa gaagagaaac   1620 

gaaagctttt gagtgatcag agtgacacgt accaggaaca tcgctgctca tggcggcggc   1680 

ggtcgacgga tcgacggtca ccggcggcag ctggttggtt tcgtaggagg agaagctact   1740 

gagcgcacac aacgagatgg aaaagaagac gaagagggta aggaggcaca ggaagatgtt   1800 

ccttcctctc tcccaggctg gcctacgcca atgattcgcg cagagattga tatttttttt   1860 

cggccgcgac gacctaaaac ccaagtcgtt gctcaagtgg catcaccaac cagcgaccac   1920 

tactactcga agaccagctc agtaactaga gtatcaggaa tttgcaaaca tggcatgaga   1980 

tagagaatat caaagcatcc actatttgtt atttctttcc acgaaattgc aaacatggca   2040 

tgcaatgaga atatcaaatc atccactgtt tgtttttttt attttcaccg tactggcaac   2100 

cgttttagtt aggacagata ctctggatct tgtaagttgt catgacaggg aaaacttcat   2160 

tgtcttacag atatttgggc cgtgttagtt tggctgcaag tgaaagagat cggcctcttc   2220 

tacattcaaa ggcatgtgac tttattactg atatataggt ccgatgaatc ataaacctac   2280 

gtatcaatga taaatgtatg atgcttttga agacaaagaa tatcaatcaa tgtgaaagat   2340 

gcatgatttt cgcaggcctt aaattgtaga cataatggct ggccacttgt gtaaatcact   2400 

tttgactgtt tgcaaaaagc tttttctttt aagtagcccc tgaagatttt acacatttgt   2460 

gttctttttc aatacttatt ttaagaacaa acccttaaaa actgatcgca caaatggacc   2520 

ctaaaacttc taacatctca gcacaaaaat ccttggagtt gaccaatggc accatgctag   2580 

aagcaagatt aatatactac ctccatccca aaatatagca atttttagct atgaatctgg   2640 

acacatacgt gtccagattc atagctaaaa aatcttacat tttaggacgg agggagtagt   2700 

aactaagcga cctgcttgtt ggtgctaaga tgttggagtt cactcctaag cttgggcttg   2760 

gctgtgactg agattggggt tcattcctac aattaagttt cataggattg tatttgtaaa   2820 

taagtattgc aaaaggaaca tgatataaaa tgtttcaata tgatagtcca taaggttgat   2880 

gcattggctg ttagtcttgg aaattagatg aaagtaaagg tgtctacttg attagtatag   2940 

tatggactgg tggtggcgaa tataagattc taagtgtaat ttggggtgtg tttgttcacg   3000 

tcaaaattag aagtttgatt gaaattggaa cgatgtgatg gaaaagttga aagtgtgtgt   3060 

gcgtagaaaa gttttgatgt gatggaaaag ttggaagttt gaagaaaaag ttaggaatta   3120 

aaccaggcct tgatttgaat gagtataata attgattatt gtccaagttt atttaccctg   3180 

aaccaggatt aattaatgaa gaccacaagc atgccaaata ccagaatacc tatcaatcca   3240 

tgtcagcgaa gagtcttaga acttttccag ttaatttata gtcattttca tctcaaagca   3300 

aacgctgaaa aattaaaatc catgacagtt tggttcaatt gcttgaagac ttgcagttgc   3360 

aaataagtcg gtcaattgtc aaagtcatct cattgatcgc tgctctcgtt tgcaaacatt   3420 

attattcttt ttcgttgaaa atgacaaatg attgttcgtt gtaattaata ggcgattgag   3480 

tcaaaaaaaa atttctgaac catccaagag aaagttcaaa gttttcatat tcatgtggac   3540 

cttttcctga caaagacgac ttggataaaa caatcctttt aatgagacca gtagcaatat   3600 

agtaaattga tagatccaaa caggtaagca aaatactaat ggataacgcg gaataatctc   3660 

atttgcttgg gatatgattg tacaattcac aacagtgtaa ctgcaggaaa agaaaaactt   3720 

tggaagaaac aaaacttgta tttcctaaaa tgataacttc tccatcaaaa ttccactgat   3780 

ttcttgatga actgtcgatt aacattgcga atacagccgt gttgatctag ttcacatttt   3840 

gaccggcagt gaagcacccg aagctgcaga gattcaatga gccaatgcat catgcaaaga   3900 

gaaaaacaaa tcaatgggta actacagaca gaagcatctg atattctgta cacgaattgc   3960 

agcttacagt ttcttaaaga agcccggttc attcctctgt gcacccttag catcatttgg   4020 

tctgaccgga ttgccattgt agtagcctta gtagtagaaa aggaaaatca gaagataaag   4080 

atttctctta atctttataa gtttgaaatt tgaaaagttg aaaactatca taggacatag   4140 

caaacaaaac agcctgaggt aatagaagaa tgcatagaag actgaaaatt aagaaccctt   4200 

ttcaaagcac ttatcaacct caagttataa caagatctgc tacatcatat ccggcaaatt   4260 

gatgtatgca gaaaactaag caaattgatg tatgcagaaa actaattaat cctgtatacc   4320 

taccagggaa ttgagcgttc tgttcctcag ccggccgtga agcttgctgt tcttcatggt   4380 

tcaatgggcg accaacgaag tagcctgcat atgaacaaca cccacaaagt aagaaaattt   4440 

acagaaaata tgttattcaa acgtgaaata gttcgcctat ggatgattgg ttaagcttgt   4500 

agcatgcaca tacctggagg attgtcactc atgttggatc aatcgatctc cagccggtta   4560 

gctcctcttc cggcgacggc gaggcgagag gtagacgaag gcgacgacca ggatgcagag   4620 

gagactgact tgagaggtgt attctaatga aacttttcag gtccacggcc gttttattgg   4680 

cttttctcta accccgttct aactttgatt atacagattt taccttggtt ttcgttagca   4740 

tattttttaa acagttaaat ggtatatttc gtgtgaaaac ttgttatata caagttgttt   4800 

taaaatatca aataaatcca tttttaagtt taaaataatt aaaatttaat taatcaaaat   4860 

ggcaatgact tcctcgtttt acgttccatt agctaccagt agtgattaga ataagcagac   4920 

ggattgtatg gagcaatcgg atctacagtt gtgccaacta gctaagctat aggtcatcaa   4980 

ccaccgagtc acagtaaaaa tgatcgcgtg gtctggtgtt actgaaagcg atacaattgc   5040 

agctcagttt tttttttcca aaatggccca cacataagat aagatggtgt gaaatttcat   5100 

attgataaag ctgggaaaaa gtacaaaaga ttataaccct acgaaattat tatcaaggaa   5160 

aaaaaaaaaa acctccacca cacgtgctag taactcctgc acataccaac ccgaccaacg   5220 

cttggccaaa tgccactagc cctattagtg acagagacat gattttcggg atgggtattc   5280 

aagatttcca tagaaaaaaa tattactcac tctgtttcat attataagac tttttagcat   5340 

tgcccacatt tatatagatg ttaataaatc taaacacaca cacatatata tatatatata   5400 

tatatatata tatatatata tatatataca tctacgtgca aagtcgcatc ttcaaattca   5460 

ttctacatag agaataacaa aaaagataaa attctgacaa aattgcaacc ttaaaactgt   5520 

cagatttttt gtttttttgt tacggctaaa atataatgaa tttgacgtta agattttaac   5580 

cctaggtgta atacaattga aagtatgtgt atgatttttt ctagatttat tggtgacatt   5640 

ttttagttgg tgtgcacgtg tgtacacgtg agggcctgtg tgcataggat atgttgccat   5700 

atatatatat atatatatat atatatatat atatatatat atatgcgagc aatgctagaa   5760 

agtcttataa tatgaaatag agaaagtagt aacattagga gctacataga ggaaaaataa   5820 

ggtagaatca actgataaaa aggcagggat tgaaatggag aagagggagg gttgaggtgc   5880 

gccatgctca tcatcgtcgt ttgtctgttc aaattaaaga aaattgctaa gatttgggaa   5940 

aaccgccggt ttcctccata gggccggtct gaccgtcgtt tgttggtcgg tcagaccgct   6000 

acttgagggc cggtctgtcc agcggcatgt ggccggtcag accggcagag tccaagcccg   6060 

agtctgtttt cgtcaggtct caggattcct tactcaggag gctatatttc gggtttcctt   6120 

tgaattctat cctgagttgg acgtggagga ggacctgtag gaggcaagat caacccctat   6180 

ataagggaca aggccggttc aattgagcat acaatctaca cacaatccaa cttagccaat   6240 

taaattgctt tttcaatatt tcaatctagt tctagtctag ttcatccatc tttgtcgatt   6300 

tgtgccataa atcgtctgcc ttcactacga gagtgcgaaa tcctttgtag gtttgtcccg   6360 

taaaccttcc gtttacccac gagacgggta gttatctatt gttctatcta aatcggctcc   6420 

gctagccggt ttagtttatc aaaacccatc ttggtctagc ttttgctaga ttgaggtggt   6480 

tggcgatact acaatcaccg caaggcgttt aggtgtctcg atcgtgcttg tctacttgtc   6540 

aaaaaagttg ccaaacacgt gccattccat ggtgtctcag actcttggtg ctcgttgtac   6600 

actcatgcca tcccatgcca tctcgggaca actcggtgtc cgcaccaaga agcatggcgc   6660 

ctacccccta tcagttttat gggtaaggca tacccaatag tgttgggtta agcttagcgg   6720 

gacctaccat ataccaagtc ttatacggaa tcaaatcttg catacggaag gtattccaga   6780 

taaggaagga gaagcagagt tctacatgga aactacaagg actattcgga tcgtatccat   6840 

atttatcttt ctagttctat ttggataagg ggacatctat gggtataaat acaagacccc   6900 

taaaagaaga gggggagacg gaccaagaca agccgagtct aaatagacag gcaacagtca   6960 

aaatatacat caatacatgc cgccagacat caacataaga gataaaccta aacagatcca   7020 

atctggtgcc acagaggctg acaagaggga tctagcgcta tctctgatat cgcccaattc   7080 

atattagagg aggaggacta ccctgttgtc gacaacgtgt ggtggttcat gccgccgtgt   7140 

tgacgatgat tagataagtt atcccaaata ttgtacttgt gtgattctga tgaataagag   7200 

caacactggt ttcaattagc aggagtagag ctattacctg gtagataagg agcctgaacc   7260 

tacatgaaaa tccttgtctc cgtttatttt accttagtct cgcttatacc ctgatacgaa   7320 

tgatccccaa actctgcaaa taccgtagtc gtgatctaca acatcgacac tctctccccc   7380 

tccccctcta actcgatgcc aaggtctcca gcgtgggtgc acgaaacctc gatgccaagc   7440 

tcaccggcac cgagtagagt ccatatccat aattagattt ttggagtcta tttattcata   7500 

aataagtttt acaaaaagag tcataatttt tttaaaaaaa tcgagcatac caaaaggtgg   7560 

acgaagacga cgaccaagaa atcgaggaaa cttgacttga gagattttta tactaagacg   7620 

acttggaggt ctccggccgt tttagttgga tgaaaacata agaaatcagt ttgttagctt   7680 

tctctaagct gtcattagcg agtagaataa ggagactgga attatatttt tgcagttgcc   7740 

gactagctaa ctaggtcctc aacaactgag tcataagtac aaggactgtt aaggtgacac   7800 

ggtatgtttc ttcctactcc ctccgtcctc aaatataacg atatgtttct tcctactcca   7860 

ttcgtactta aatataaagg attttaaaca gatgtgacac ttactagtac atgtccagat   7920 

tccttgtact aaaaaaatgt ctcatccgtc taaaatctct tatattttgg gcaaagggag   7980 

tatatgtcca agatgcagcg aacagcctga ccagtgagct ggctgcagga cagtaaacta   8040 

atcaaaactg tatcttttct aatttgcata ctggactaca gatattctat tcctttcgat   8100 

atgaacaatt ctgatttact ttttcttttc ctttttacta taggcaaaat aatctattga   8160 

gcaataattt ctcgagtttc tggtccattt aaaaagaatc cagcatcccc cactgcatgc   8220 

ggtttggagg gtatactata aattttgaga tcaggaaaaa ggaagcttcc acagcggact   8280 

cccgtcctac acgcacaact tggccagttg ataattggca ctgcaaatgc ttagccgcgt   8340 

cgacttcgcg tcaagtcgtc ggcggctagt tcagagaaac agacaaggat ctgattgaga   8400 

tttgaggcta gtggctttgt gctttatatt ttcttcgttg cctatcttaa acctcacatg   8460 

ctctgatcgt ctcgccagct ctgctcttct agacgctctg atcgtctgca gctcaggtta   8520 

gattgatttc cactggatct tgctttgtat catctagcta gtttgtagct gttatcagct   8580 

ttaacttttc tgattatgtc tgctggaaaa ttctgccttt ttctttcgtg aatttcgcct   8640 

tgttgagagg agggatcact aattagtctc tttgctagaa aatattggga aatttgttct   8700 

gaaatttgac cctgagcgag catatctaag gccagcagca cattctcagt tcagagatgg   8760 

ggaaagaacc tttgtgttgt tgttttgttc agtgctgatt caactgcaac atttagcgat   8820 

tactgttgtt tgcagtgcat caccttaaat actgtgtgtt aattacatgt ttcccgtatt   8880 

tttatcattt attatcttat tgttggccat ctactgcaag gacatcttaa gctaaaattg   8940 

aatgcccgtg gaaactatta ccaatcattt caccaagaac aaagcatgaa agatgagtag   9000 

cccaacgaaa ttttctaatg gccaatcaat ttgcgatata gttgaaatgt tgctttacaa   9060 

aagatccagt gctactatag cggctgtaca gaattaatat ggattacaaa aggaagacaa   9120 

aaacaactag gaccaaataa agaaacagta acaagtcaac cagataaacg agatttgaag   9180 

ggcaaacatc tattatatta ttaaaggaat agaagaagaa gcctctatgt ttgctctcat   9240 

ggtctataaa ttctcacatt aattagggaa aaagaaaaga cagagtccat atagaaatac   9300 

aatttagaaa tagctgaaat tcagaattaa aaaatatgga atcttagaag aggagactag   9360 

agtccatata gaaatacaat ttagaaatag ttgaaattca gaattaaaaa ataaggaata   9420 

ttagaagatg agactagagt ccatatatag aaatacaatt aggaaataaa taactgaaat   9480 

tcggaattaa aaataaggaa tattaaaagt agagtatata gtccatatag aaatacaatt   9540 

aggaaataac tgaaattcgg aattaaaaat aaggaatatt aaaagtggag tatagagtcc   9600 

atatagaaat acaattatga aataactgaa attcggaatt caaaataagg aatattagaa   9660 

gtagagtata cagtccatat agaaatacga ttaggaaata actgaaattc ggaattaaaa   9720 

ataaggaata ttagaagtag agtatagagt ccatatagaa attcaatgaa gaaaaaaaat   9780 

agaaattcga aataaaaaaa taaggaatat tagaagttga gtatagagtc catataggaa   9840 

tttaaaacta actaaaattt ggaataaaca taataaaatt aaaagtagag tttagagtca   9900 

gtataaaaat acaatttata aataactaaa atttaaaatt aagaaaaaca tgggaagaag   9960 

agtttaaagt cactatagga atacaattta aaagtaactg aaattcgaaa ttaaaaatta  10020 

aagaatattg aaagatgagt ttagagtcca gatagaaata caattagaaa taataaaaat  10080 

tcagaaataa aaataaataa tattggaaga agagcataga gtctatatag aaatacaatt  10140 

tacagaaaat tcggaattaa aaaaaagaaa tattaaaaca cgagtctaga gtccatatag  10200 

aaatatatat aatttacaaa taactaaaat ttgatattaa aaataattaa taactaacac  10260 

gtatataaaa tataatatga atattatgta ttagtagttt tgtaaagtta ttgtaaaatt  10320 

taaaattatg ttgtcatttt aatatatttg aataatataa tgagaaaaca tatatgcaat  10380 

tatatgggaa aaaacataat ggtgctagcc gcgcagtctg cgcgggccac catgctagtt  10440 

tttattataa gaataaattg taagcgtgtt gggattgaac atgggacctt gggattgaaa  10500 

ccacgcaccc cttatcacta cattatcaag tgcatctcat aacaaatcaa ccatgaccct  10560 

gcctatacaa cagatctaca ccagtgctaa acggtactcc ctccgttcgt aatacgaggg  10620 

attatatttt ttttaataga aattaaggaa taggaaaaag tacagataaa gggaagcact  10680 

aattggatta ggccgattgg cacattgaat aaactaaaaa aaagtaagaa aaagctaagg  10740 

gcccctttga atcacatgaa taaaaaaacg gaggaatatg aaaaacatag aattctgaca  10800 

ggaatgtaag tgtaaaagag gattgcaaaa cacaggaata acgtatgaat gaccatttga  10860 

ttggaccaca gaaaaaacac aggaatttga tgagagataa agactcaaaa cgattttttc  10920 

atgaggttct acctcttgtt aaaattcctc caaaacttgt atgggaagag gcattccata  10980 

ggaattttat aggattccat aggattcatt cctttaattc aaaaggcttt gtaagaaaaa  11040 

ttcctatagg aatgaaatcc tctaaaattt ctatcaattt cctttgaatc aaagggggcc  11100 

taaaatgttg ctgcatccct tctgttgttt gctcacctca ggatccacga tcccttgtat  11160 

ttgtggacaa atcgaagggt tataatctct tatattcaca gttagagggt agttcttttc  11220 

agcaactcaa aacgacaact tttttctttt tcgttaatgt gttttccgta ttgctaaacg  11280 

gtgtgttttg taaaaggata tgtaaaatgt tgacctctac ctgttataag caaaagaatc  11340 

gaaccacatg cgcttcagca cttccatgct gagaaagaga acactggaat atgtggtgtg  11400 

catctctact tcatattaag agcattgctg gtctgctcct tgtcacttaa aaagaaattg  11460 

agtcacagtc atgttcttta agtacttatc agtaggttca gcagcttaat gccagaattc  11520 

acaagtaggt ttctactgac aagaaaccta tcatctaagc atggtgtaac agactagaag  11580 

agcagaatcc aaaacagagt tgtcattaga aatggctgct taaaagaaaa gtaagattag  11640 

aaacaaacta tgatcatgtt tgatattatg ttcagatata tctgggctgt ttcatatata  11700 

cttcattgca tttaagaaca tggaagaagt gatggtgcat gaaatactca cacatattag  11760 

atactggcct ttgtatgaag cattaaaaag ctgggcacat atgagttata ctaaatgatc  11820 

aatctatctg tggaaccatt aaaaacctga atagagacct acttcaagaa acaacacact  11880 

caactaaact atgagactat ctgattatga gttactttga tctcctatta agggcctatt  11940 

tgggggagct ttagattctg agaagcaact gtttggtagc tagattctga gaatctggaa  12000 

aagctctgaa acccagcttc tccagcttct ggcttcttag ttcatttttc agattctgta  12060 

actacagatt ctcagaagct gtggactgtt tggggtagct tctagcagaa gcagcttttg  12120 

ggaaaagtta cagctgggac aagctccccc aaacaggacc taagttacac agttggtcac  12180 

attgcagagt tatgaaacaa ttgccataga acattaccct tacaattaag attactgttg  12240 

aggctggtac gtaatgagga gctcctttac ctatatctgt tggtacacca tgattaacat  12300 

tagaaatata tatatatatg gcttgcaaat gcccacaagg gcccaaaaaa caatcttagc  12360 

tgcaattgtt ttacaactgt aacaacaacc ttttttatct tatcaattcg ttatgtgact  12420 

atctccatga ttcatgattc tgttctgcag cactaaggta atggcagaag ctgtgctgct  12480 

tgccatctca aagatcagta ttgcattggg agatgaagcc accagagctg tcatagccaa  12540 

actgtctggg aaggtaacta acttgaggga acttccagac aaagttgagt atatcagaag  12600 

ggaattgcgt gtcatgaaag atgtaataca agatttagat tccacaaata ccaacatgaa  12660 

tgttgtaaag ggttggatcg acgagctgcg gaagctggct taccgtgttg aagacataat  12720 

ggacaagtac tcatactatg cttgtcaact gcagcaagaa ggatcagtga tgaggttcgt  12780 

aagagtacat tatgcaggtg ttttcagtga agttgctagt gaggtaatga agataaaggg  12840 

tgatattgaa caggttaaaa gacagcaaac ggaatggtta cctacagttc agctcattcc  12900 

aagaactccc actgacatcg aaacaccgca atctcaagga agaaggaagt tgcttgaatg  12960 

tggcgatcct gtggggattg aatacaacag gaaaaggttg cttgaattac tgtactctga  13020 

agaaccaggt cacaaagtaa taacagtgtc tggtatgggt ggactgggaa aaaccaccct  13080 

ggccttagac gtatatgaac gtgaaaagat caagttccca gttcatgcct ggatcactgt  13140 

gtcacagact tggacgatcc ttagtctttg taggcagcta gtcagtgagc tcatacgcat  13200 

ggaacaagaa tcatcagaat ctaaggaaga tctaatcaac aaaatgggcg ttcaagattt  13260 

gacagaagaa ttaaacagaa ggactgaaaa cagtacatca tgtttgattg tgctagatga  13320 

tgtctgggac cagaacgtgt acttcgaaat acagggcaag cttaagaatc cccaagcaag  13380 

tcgcattatc atcacgacac ggatggaaca tgtggcagtt cttgctccct ctgaatgcca  13440 

tctcaagata caggctttgg gtgaaattga tgcattcaac cttttctgca gaagggcatt  13500 

ttacaacaga aaggaccata ggtgcccgct ggaccttgag aatgtggctg cctccatagt  13560 

aagtaagtgt aaggggctgc ccctagcact tgttaccatg ggtgtcctga tgtccacaaa  13620 

gctacaaact gagcatgcct ggcaacaaat gtacaaccag cttcggagtg agctggccaa  13680 

aaatgatgat gtcaaggcaa ttctgaaact aagctaccat gcattaccag ctgaccaaaa  13740 

gaactgcttc ttgtactgca gcctgttccc tgaagatttt cgcatatctc gtgagagcct  13800 

tgtgcggtac tgggttgcag aaggttttgc ggtgagaacc gaacacaata gaccagaaga  13860 

tgtggccgaa ataaatctca tggaactgat ccaccggaac atgcttgaag ttgacgagta  13920 

tgatgagctt ggcagggtga gatcttgtaa gatgcatgac attgtgcgca acctggctct  13980 

ctcaattgct ggacaggaga ggttcggttg cgtaaatgat tatggagctg tggaaaaggt  14040 

tgattgggaa gtccgtcgtc tgtcattatt cttgaacaat ggaaaaggtt gtgcatcaac  14100 

agtgaaattt ccacatcttc gcacactact tgaaacaact acacaccctc ctggattgtt  14160 

atcctcaatt ttgtctgaat ccaaatacct cactgtccta gagctacaag attcagatat  14220 

cactgaagta ccagcatgca taggtaaatt gtttaattta cgttacattg gcttaaggcg  14280 

gacaagactc tgctcactac cagagtctat tgagaagctc tcaaacctgc aaactctgga  14340 

catcaagcaa accaaaatag agaagctacc acgtggaatc actaagatca agaagctaag  14400 

gcacctgcta gctgatagat atgaagacga gaagcagtca gtgtttcgct atttcattgg  14460 

aatgcaagca cccaaagatc tgtctaagtt ggaagaactt cagactcttg agactgtgga  14520 

agccagcaag gacttggccg agcagctgaa ggaactaatg cagataagaa gtatttggat  14580 

tgacaacata agttctgctg attgtggaaa tatttttgct acattatcaa ctatgccgct  14640 

tctttctagc ttgcttcttt ctgcaagaga tgagaatgaa cctctttgct ttgaggctct  14700 

ccagcccatg tccaaagaac tccacaggtt aattatcaga gggcaatggg ccaagggcac  14760 

attggactac ccgatatttc gtagccacac tacacatctc aagtacttag ctctaagttg  14820 

gtgtaatctt ggggaagatc cactggggat gctcgcatca cacttgtcaa acctcactta  14880 

tctaagactg aacaacgtgc acagttcgaa aactttggtt cttgatgcag aggcgttccc  14940 

ccacctgaag actcttgtgt taatgcacat gcctgatgtc aaccagataa acatcacgga  15000 

tggcgccctt ccatgcattg aaggtttata cattgtatca ttgtggaagc tggataaagt  15060 

ccctcaaggc attgaatccc ttgcctccct gaagaagctc tggttgaagg acctgcacaa  15120 

agacttcaag actcaatgga aaggtgacgg gatgcaccag aagatgctgc atgttgcaga  15180 

ggtccgtata tagatgttgc agattggttc ttggcgcggc ggctttccca tgcctgaaga  15240 

cacttgtgct gaagcacatg cctgatgtca accagctaaa aattataagt ggtgcacttc  15300 

cagtcattga aggtttgtac attgttgctc tgtcagggct ggagagtgtc cctcctggca  15360 

ttgaaaccct tcggaccctg aagaaactct ggctggttgg tctgcactgg gactttgaag  15420 

ctcactggat tgagagtgag atggaccaaa aaatggctga ttgtgtaggg gactaggagt  15480 

gctagttacc ttctccctac attagcaatc ttgtttgatg cctctgcatt tgtcaggtcc  15540 

attgaccatt ccaataagtt catcgttatg gagttattgc tactttgcta gcactacctg  15600 

aaacattcgc tttcttatcc atctggacct gaagtgttct tctgttattt tgattgcttt  15660 

ggagattgtt gtaagaggcc cttttactat tgaactgcgt ttagacaatg tttttccttt  15720 

ctgttcattt ttgagatcgt tgttctgcag aatgatctca tagcatttgt ttattatcta  15780 

atggtgggtt cacttttatg agttagattg cattctcgaa tttcagaaaa aataactaaa  15840 

gcaatcagat gatgcagcgt ttgaactttg ttgtaatcta ctactattgt ttagctgaag  15900 

aaattctgac aactcccatc gtaggccatt gcaagcaaga gcagatgcat tgctgcacag  15960 

atgtactatg caagtgtgaa ccctctgtgc atttcatgtg ccagtatttt aaccagatta  16020 

aacatgcaag aaggatgaac acctagaaaa cataattgaa cgcactagaa cacgaatctg  16080 

ccgcgcaatt gacacgaaac ccttaaaatc gacacctggg aatatcttca tggaatgaat  16140 

cgaatggggc aaccccacca aaatcgcagg gaactgaatc cgggcgttac ctgaagaatc  16200 

caggaagagg cgccgccgac ggtcgtcgtc catggccgcc gccggcgagc gcttgcttgg  16260 

gctcgtttac tccgccgccg cagagtcgag gggattggtc tccgatctga tctgggccga  16320 

cgggttcatt tcattatggt ataagttcac tttaggttcc tcaatttgtc gccgagtcta  16380 

ccattcaccc ctgaaccgaa atacggtata gcacatcctc aactcataat accttgttaa  16440 

ctttgatcac tccacagtac agtgatcggt tttggctgac acaactcaca atacctcgtt  16500 

aactttgatc actcgataat acagtgatcg gttttggctg acatgatgag ggggacccac  16560 

gtggacccca tatgtctgga gaaagctacc catcggacgt ccgatgccta tcaaaaaatc  16620 

ggatggtcaa atgttgcagt ttaccaataa gtgaaacatt aagttatata cggtaaaaaa  16680 

aatcagcaac taaaacattt aaatatttta tgaaacatgg tgaagataca cgttgaaaca  16740 

tattgctatc acatatgaaa caacaagtag catatgtttt tcctttatca aaatatagtc  16800 

atgcgatatc ttgttgtaaa gatttaatta aaacgaatac aatggtgtaa tcgggtcata  16860 

tattggataa gtaatttaag agaaaaatca ttttgaagct tgctaaaata aatgcatgtg  16920 

tgcatggatg agatggagag agaggaggga gagggtagta gcagatagta tcaggaattt  16980 

tttgaaatac gctgaagacg catgttgaaa catatcacta tcacgtatga aatatttagt  17040 

tttaacggtt tgaaacacat gtttttttat ataatataat catatgatat cttattgtaa  17100 

agatttaatt gcaacaaata taacggtgtg atcggttcgt agatcgaata agtaatctag  17160 

aagaaaaaat atttaaagag aagaggtaag aacaaaagga aacaattggc catggatgtt  17220 

acagtgaaat agttcatcct atccatatac cgatttacag tagatgacgc gtccgatatt  17280 

tcggttttga tcggacgtac gatataaagc attttcccca cgtgtcagcg gcccatctct  17340 

tctccctcat ctgcctctcc ctcttcactc ttttttccca tctcttgagg gcggcgcgca  17400 

gtgaagcgat gggaggcgcg cgccacgcgg cggccggcag aggcgatgac ggagtcaccc  17460 

tgcgctccag tgcgtcagcg aacgtggagg gaacccacgg cttgccagac ggccggcgtg  17520 

gtcacctgcg cgggcgacac ggcacagtgg cggatgtccg tgtccgtgca ctgttcccgc  17580 

cacaccattt tgaaatagtt cactttagct gtcactaaag acaatctcaa atctatctac  17640 

gttcttgtag taaaaaaaaa agtcaaaatg caagttcttc ctaacgctac agaatgcaat  17700 

atactcaacg gagtttacaa ctatccttcg atgacatgtt ataatgtgta accttaacat  17760 

cttaattaaa tcattaatta atacatacta caaaattatc agcatttaaa atgcagaaac  17820 

tatattagta gtttttgcat aaaaaaagat atttcataca gttatattta aattattttt  17880 

gctaatatat agtttgagag agaaatgata gcatggacct tgaggactag tatatcgata  17940 

tccaaaacgt catttctttt ttggtaaaga agataccaag actatcataa gtgtctactt  18000 

attcgcttat cagccatagc aaaaatttaa atcttgaaat ttgatttttc taaagttaat  18060 

tttgggtatt gttattgcag ttcattattt ttcaatatta gctttaaacc acaaacaata  18120 

tcaatataaa acattgctta atcatttttc tactatttat tgatcgtatc attctagcac  18180 

aattcacacg tttgaaatta ggtttttatt aatgcctcac taaaactatg gcgttacaat  18240 

attatgtcat taactatttc ttaccagaga aaatattttt ctattactta cgcaacaaca  18300 

atttatttat ttatcataac aagcttataa tagatgaaac attaccacca attaaactat  18360 

atcaatattc ttctcacata caacaagtaa taggctagcc atgttccttg caaccggtaa  18420 

tcaccaaaca aagcacattt agttgcaagg gagatcagcc tcttccctca ctatgggcac  18480 

gccatattaa actagtgcat gttcattcaa atcaaattga gaagcatgtg gtgcaactat  18540 

ttccacttgt ggagccacaa ccaccgaaga agaagcacct tgtgcgtgga gctcgatgat  18600 

gcggtttcta atggcctccc ggagcttggc cgcctcccgc ttgacatttt tgaccatctc  18660 

gggagataaa tcatttaagt tcttgcggtg tccacctcct atctcagaaa ttatgttggt  18720 

gatctcacgt ttgtagttct cagccttcag attgtccagc ttcttctgga gcttcataat  18780 

ttgctgctgg agtagggtct tggagtcttg catccacttc ttctggacag cctctggcat  18840 

gtccatgagt ttgctccaca tgtttttggc ctcttcaata gatggccata ccactggatc  18900 

acatgcttca tcgatgttgt acaccacgat actagcttgg acactgcaca agattgatag  18960 

ctctgttacc tttttaatca atccagcacg acgcctccta agagtcactc tgcgggcagc  19020 

gtttttggta tgccgtgcca tagcacacct cacctacacg ggcgcacgga cacgaaccta  19080 

gtaatgaaaa tgactcttgt gagagttgtt tttctgtgtt tgccgacaga ggtagggtga  19140 

tctttttata gtgaaaaacg tggtattcta ttttaggtga atggcgcgta aagagctcta  19200 

aaatagtgaa aaagataaga caccataata gagagcgaaa ctttggtgta atttaaatta  19260 

taatgagata agataaggta accgtaaagc tagtgtagtt taaaatagct tcaggatagg  19320 

gtaaatcata tataacgtcg gcatatatta ggtgctattt acatttatgg gatttgtcca  19380 

cacacaaatg cagatttggg gcttgaggaa tttggtccat ggctcgaggc cttagcctaa  19440 

aagtttatgg tgctagactt tttttatagt gttaatttat atggggctca atgtgggcta  19500 

tgctatccta agattttatt aatcagcaca cggcttgtcc gtgggcatag aacttgccta  19560 

gttgtcgtac ctatatggct atatatgaaa tgttagcaac acttgtaaca tcaatcacat  19620 

aataatactt gaaaagttat tgtgatcatg tcattgttta ttcagtgtgt tgtgttgttt  19680 

caatagagta ccaactccac ccagatggtg cggggccccg ctcacccgtc gggctccctg  19740 

caggggcggg ggaggttttc cacgtggtga ccaatgcggg ggcggggacg ggggctggtg  19800 

ttgatgaaaa aatcgaacac accggtctgg gagatctgct tagctcctgt gcaggtacaa  19860 

aggttgatga gatgcgagcg tgctagtcag tttgatcctg caactgacaa gatatgtaaa  19920 

tagtagatca aatagccgat cgtctgacaa gccgatggag tggttctagc cgatagccga  19980 

taatagccga tgccaatacc agccgatagc gatagggttt aagcaatcgg ctatatgtcc  20040 

aatgtagata atgatataaa gacaatcggc tgatgatgat gtaataaaat aacaatataa  20100 

tccagtataa gccaatcggc tagcattgat atgataaata agcatcgatc cgaaggttaa  20160 

agcacacatc ggctggaggt ccgatgtcat gaaatccaca agattagatt aaacaatgaa  20220 

acctttgttg tcatcggcta aatccaactt atatgtatat gcaatcctta tgagccgatg  20280 

caacgtccag ataactcacc ggttgaaacc ccgatgaaac ccttattggc aatcaaaaag  20340 

caggctagag attatggttc taagcacgac ttagtagatc aaacttaact gatgcagcac  20400 

taagtatgaa aagaaacaca atatctagac aatcaagccg ttgactgatt ttcagggtgg  20460 

tagatgtcta ggctaatcta atctagcaaa gcgatttagc cgatactggc agaaacccta  20520 

aagtgagaga cagccgatag agctaaattg agatgctagg actagattaa catagacata  20580 

tgataaatag ccaggcaaat atattatcca aaccagagta atcctatagg tcgaatgtac  20640 

tgatgcagcc ttgaacgacg ccgacgtaga cgatacaatt gcctggaccg gcggaacatt  20700 

ggacttatcc cttcgccgga gatcgaagac gatgcagccc cgcgtcgggt gccaggttcc  20760 

gccggaatgt aaaaacaaaa gtagaagtaa aaagggtggc gatgcgccga attgtattga  20820 

tcgtagtgat agattacata gaccccgggt gtacatattt atacccatgg gttgatacaa  20880 

gtccttgtcg gacaagaaaa aaactttcct aaagataaaa ggaaaagata aagtccttat  20940 

aggatactaa acacactttt ctaaagataa aaggaaacta acaaactatt cctaattaat  21000 

agataacttg ccatgccgca ttctctttga actcggtctc ttctagataa gcttccttta  21060 

gtagatcaat tttcttaacc gaatatagca agaatccgac aactgacgac ttgacaattc  21120 

tcatcggcta atcgcaggac ttcaaagccg atgctgactc taagccgatg actactccgg  21180 

gcttaccaaa tttcactgtt aacagctggg ggggagggaa tgcggggagc gggggggttc  21240 

ctatccaacc cggccccgcc ccgccccgct acccccctag gtgagggtgg tgagaacggg  21300 

gacgaggcca cactccggat agtgcgctgc cgttgccgct agatcaggag gagtttgagg  21360 

ctggggagta gggagagagt aggctagcag gggcgacgaa aacggcgacg atgaattagg  21420 

atggaaggca aagtcaagta gtcaacacca gcatggggca gccctatcaa accactcttt  21480 

tttttatgac tatcgtgtcc ctgcgaattg aacggacata tttcaatcgt actggtggta  21540 

cttagtacct cctgatacat cctcatggat ggaaaaaact ttcataatag taattgatga  21600 

atttgtaggg aaatttaagg attgcatcac ctgagtttag gggttttttt tctctggaat  21660 

tggagaatgc aatcttgctc atacaattgg agtacgagag cacatactaa tccattgttc  21720 

taacctaaag aaagccagag aattcccaca ttatgccatg gcaatgctag aacttgcaca  21780 

ttgctgcact actgtgtgaa ctgtggagct gtgaaccctc tttgcttaca tgtggtgaat  21840 

ttgcagccac atgaaacatg ctgcaagcct gcaagaatgg agcaacaaag actgaaagcc  21900 

ctagcccacg aacgtcgaga ggaaccccta aaatcgagac caacacattt gggttgggat  21960 

atctctatgg aacaaattga atagaaaccc ccaataaaac cataggaaac tgagtccgaa  22020 

tccttaccac gaaatccaag aaagagccga cgccgcatgg gagcttgatg gccgatgcat  22080 

aggagctcgg caccaaagca ggcgggcagg ctgccgccgc cccgtcagtc gctatagtcg  22140 

tcgtcatcat tgtcggcggc gagcgcttgc tggggggcta ctgctccctc caccacccag  22200 

actatgccat aaggcgggct gggattagtt gccactgggg tgagccgacg cgacccaact  22260 

ctgctcgaga tgaacaattt gagcattgtt tatatatgtt tgattattct agtttggtct  22320 

tattcttcta ggtccaatgt ggaattgtgt tctttgggct tcttctggcc tagccaccta  22380 

gggtgttaat ggatcacaaa attttcggtt ttgcgagatg ttcagaagat tattataatg  22440 

agtaattctt tttttttatt acacaacaaa ctcacatgca catatatcac tgtacatgta  22500 

acaccacact cacacactca cgaatacgct ccctaacaca ctctcaaata gatgaaaatc  22560 

agcagcacgt atatgatttc actgattaaa ttcgtgttga aagcccactt acatatgcat  22620 

aatatttgtg ggtataactc atgacttcac taccgtatca ctgatgcttt taagttgtct  22680 

atgttgttga actcaaaatg ttatttctaa cagtagagaa agcaatatac tcgacgaagt  22740 

ttaccagccc gaaaacggta tcggatccat ctgagttgaa tcacacttaa cactatttaa  22800 

cactatcgac ctcgctttaa cgcaaaaatt ccaaaatcag aattcctagc gaccgtgctg  22860 

ccttccttat aagctgctcc ctctcttctc aaattggcga ggtgggacta aagttagcta  22920 

cagctgttgc tgctgctctt gctctgctcg ctgctgcatg ctagctactg ctgcttcatg  22980 

ttgctgctgt gggctgcatg catgcatggg ctggcctgct gctgcttgct acttgctggg  23040 

ctgcacgcat gggccaaggc ccaaggctta gctgggctgc tagtttgctc ttttctctct  23100 

tttctttttc tctaattatt gcggggcgtt acagtgagtc atttactcat ttgcccatct  23160 

aattatgcac tcgagcatac ctttgggtca ataatgcatg gagggatagc ggcttggcaa  23220 

taaagaggag ccctctccct ctcttctctc tcaccatagc atgaagaagc gctctcctcg  23280 

ccatctccca ttgtcctcat gcagaagcag ctgtgcggcg acagctcgac gatgaggagg  23340 

aggattagtg gatccgatgg tggagcttgg gctgcggcaa gtcccgggcg atgaatccgg  23400 

cggcggtaag tcttccgtgg ccatgttgga cttcaactgc tgcgggtcaa tgacagcaac  23460 

gccacggcga ggatggtggc taggctacat cgacatggcc tccttgctct ctcccatcca  23520 

caagccgcat gcatcagtgg cgcggtagca tccgacggca tcaagaaggg gaaggccaca  23580 

tccaacggtg tagggcatta ccgtgtcttg agattagtca aatttccatg aggtagtagt  23640 

gtgacctcat gaaataaaaa atattactgc atcatgaaat tagttaaaaa ttccatcaca  23700 

tattttctat acactgatgt acaaactgga ttgaaaaaac aagaaccact gaaaactagg  23760 

atcaaatgga cacaaagggg ttttttccct tgaaatgagc aaacttgaaa aggcatggac  23820 

aaattggtag ttaggcttca aaacaggatt aaaagcgcaa atgccccatt gtttattgat  23880 

tataactata aaagacggaa tattgccacc aactaaacta tcgaaatatt ctcctttcat  23940 

gcaacaagtg atagactagc tatgtgagga ccatgttcct tgaaaccagt actcatgtaa  24000 

aagtcttgcc aaacaaagca cctttagttg caggggagat cgacctcttc cctcactatg  24060 

ggaggatcat catcaaccgc tgcaggttca ttcaaatcaa attgaaaagc atgtggtgca  24120 

actatttcct cttgtggagc cacaaccacc gaagaagaag caccttgggc gcgaagctcg  24180 

acaatgcggt ttctaatagc ctccctatgc ttcgccacct ccagcttgac acctttgacc  24240 

atctcgggag atagatcatc taggttcttg cagagaccaa ctgatagctc agaaattata  24300 

ttggtgatct cacgtttgta gttctcagcc ttcagattgt ccagcttctt ctggagcttc  24360 

gcaatttgct gctgaagtag ggtcttggag tcttgcatcc acttcttctg gacagcctct  24420 

ggcatgtcca tgagtttgct ccacatgtct ttggcctcct caatggatgg ccatgccact  24480 

ggatcacctg tctcatttat gttgtacacc atgatactag ccttgacact gcacaagatt  24540 

gatagctctg ttaccttttt aatcaatcta gcactacgct tcctaagagt cactttgcgg  24600 

gcaatattgt tggcctggta agctttgcca tggcacacct cacctatgcg cgcgcacaga  24660 

cacggacttg gtaatggaaa tgacttgtaa tttgtttttg tgtgtgtttg caaatagagg  24720 

taggtgacct ttttatagtg aaaatcatgg tattctattt taggtgaata gcgtataaag  24780 

ggctccaaaa gagtgaaaaa tataatacgc catataggga gaaaaacttt gatgtaattt  24840 

aaattctaat gagagaagat aaggtaaaca caaagctagt atagtttaaa tatcttcagg  24900 

atagggtaaa tcataacgtc ggcatagatt aggtgctatt tatgtttgtg ggatttgttg  24960 

ttcacacata tgcagatctg ggccttgagg aacctggtcc atgtctcgag gccttggact  25020 

aaaagttcat ggagctagac tttttcataa tgttagttta tatgggagct caatgtgggc  25080 

taggccatcc ctggacttat taatcaacac acggttgatc caccgacata gaacaagcct  25140 

agttgtcaac ttgtcatata tatatatgga atggttagga acacttgtaa catcagtcat  25200 

ataatacatg aaaaattatt ttcatgtcat cgtcctatat ctctaactct atgttatctg  25260 

ttttgtgcta tgtaaattgc tagagtgcgc ggtaagtaaa ggttgccaca ccttgtaaat  25320 

atttggtact ttgatctttt cctgtccgac cacgcatata caaacgtgac acacgcaagt  25380 

aaatatcacg ggtttaactt ggtaagatac atttcatacc ccgcaagaac gcgcatctac  25440 

ataaatcccc ttgaggtgat caaggataca tccgaactcg aattattttg catctacctt  25500 

atagccgtgc acataccttg aacagatgta cgcttcacgt ggaattttgt aaatagtttc  25560 

aattttgtta catatttatc aacaaaattt cttttaaaaa gttgacaaat ataattatag  25620 

tacaatcgta catagtgtaa tgtacttttt tagtcaaagt tctttaggtt tgagcaaatt  25680 

tatagaaaaa ttagtaacat ctataacacc aaattagttt cattaaatcc aacattgaat  25740 

atattttaaa aaaatatttg ttttgtattt gaaatatcac tatatgtttc tacaaactta  25800 

tcaaacttta aaaaatttga ctaagaaaaa aaatcaaatg acttatcata taaagcggag  25860 

ggagtaattt ttatataatt ttgaactgtt agatttgttt caagatttgt gcaaacaagg  25920 

aagggaaaaa attatgtgat ttcagtgtca acaaaaattt cacgaatttc ggttttttca  25980 

aaactttttt acacgaaaat atttgaaatt taactatttt tactaaattt gaattcataa  26040 

aaattactaa aaaacctgaa aattgcgagg gagattgttg cttgccaggg ggtccaaaat  26100 

tagtagcgcg aaaacatcgt ctatatatag gatatggatt ttcatccctc tacaattatg  26160 

caagaccaaa tttaacttct acaagttgca acaaaaagaa caaaataagt tgaaaatagt  26220 

tattcaactt ctacgaaaac tatcaatcca atcaatagct atcaccatga ctaccatgga  26280 

agacgccggc ggccgcnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn  26340 

nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnngcggc  26400 

cgcgacggag aacctcatcg acacgatcct cccgccgggg tcggtgagca cggacacggg  26460 

tctcgtggtc accagcgcca tctacttcaa cggcacatgg cagacgccat tccgaaagca  26520 

ggacaccaag aaggacaagt tccacctcct cgacggccac ggcaccgtcg acgcggactt  26580 

catgcgcacc ggcgaggacc agtacatcgc ggcgcacgac gggttcaagg tgctcaagat  26640 

gccgtacgcc cacgaccacg cggcgccaca accctcgccg cggtactact ccatgtacat  26700 

cctcctcccc gacgagagcg acggcctgtc cagcctcgag gacaggatgg cggcggccgg  26760 

tggcggcggc ggcggcgagg gcttcctcag cgagcacatg ccggtgcgac gcgtcgaggt  26820 

cggcgagttc aggatcccca ggttcaagct ctccttcagc cgcagcgtcg tgcgcgcgct  26880 

ccggggtgtc ggggtgaacg ccgtgttcga tcgggccgag ctgccggaca tgatcgaggg  26940 

cgagccgctg cgcgtgtcgg acgtcctgca caaggccgtg atcgaggtga acgaggaggg  27000 

caccgaggcg gcggcggcca cggcagtgtt aatggaaggt gcggcgcggt atgcgccgcc  27060 

gccgccgcca agggaggact tcgtcgccga ccatccgttc gccttctttg tggtggagga  27120 

atcgtcgggc gcggtactct tcgcggggca tgtcgttgac ccgacgaaat cttagtcaac  27180 

agaagtatag tatcattgtt tttggaaatt gctcgagtct taacgctaat gtctatttct  27240 

atccgtccca aaaaaaaaaa aactgttttc tcttttttat tctcaaagat aatttccaaa  27300 

aaaaaaaaag aaaaactgtt cttctaatga gaaactgcgt gggtatttaa atggactgca  27360 

cgctaaattc tttttttttc tcaaacatta gataattaga aaattcccaa aaaaagcaaa  27420 

gtgagaattt ttctcttttt tttcagttaa ttagagtttt cgattgattt gttaagaaaa  27480 

actgcgtggg tagttaaatg gactgcataa ggcggacaaa gtaccgtacc ttggcttgcg  27540 

aagttgcgat gggaaataga tatttaagtt ctttcagaaa acatattgtt cttcacgtgg  27600 

gcctgtatga taacttattc aaaataggtt attcggttat tcctcgtcca tcagatccaa  27660 

cattagctat tgatttgtag ataaaaactt gatctgtact ggtcacaacc taattaaaca  27720 

tgtctagccg cacatcatat ctactgcttc ctctatttca caatgtaagt cattttagca  27780 

tttcccacat tcatattaat gttaataaag attcattaac atcaatataa atgtggaaaa  27840 

tgatagaatg acttacattg tgaaacggat ggagtactac gtatacctgt tgcataatat  27900 

atgggatttt ggtgaagtac taggatatgt cacatccact caaaatcatt catattaata  27960 

tgtcgcatcc acctaaaatc atttatagta ctacgatatg tcacattcac ccagaagctc  28020 

ttagggtgtg ttcgattggg tggatgagcc tgaatgggag atggccgccc gatttttcgt  28080 

gttgtttgat tggagggcat gatggatggg gcgacctgca atatgaaata ttccctcgat  28140 

atgctggatg agtgcattcg atcgatttgg ctggatgaag ctactcagtt ttggtctggg  28200 

tgatgtgtca tattctgatt ggttgtggtt ggtttaattt cttgttaagc aagctctaaa  28260 

tgattttttt tctcctaaac cgtttattca atttatgatt tgattacacc attatatttg  28320 

ttataattaa atctttaaaa caagatctcg aatgattata ttttgataaa aaaatatata  28380 

tgacaaattg gtctcactaa cttttggctt ttcccatcca tgttatatcc ctccaaccaa  28440 

gaaattggat cgccatatct atacaaacca aacaaaaaat tagattggca tatccaacaa  28500 

agtatagatg gccatatctc atccatgtat gactgtgacc caaacacacc cttatattat  28560 

gggacatagg gagtatcttt tacgttggct ccctattctg gcgtgttaga tctaatcatg  28620 

gtggcatctc cgatgatcga ataggaaaaa aatgcattaa agttaaaata aaccgccaac  28680 

atctctccgg tttaggagaa tttagagtat ttaccatcca attcgcatgc cccaactttt  28740 

ttactaccca attcatatgc cctctataat atatccttag gactgctaat tagtctattt  28800 

ggtaccactt tatttgtttt tcatgtattt ctcttttctt aatcccattt gtattttttt  28860 

taagttttgt ggactgtttt gcccctggac ccacctgtta gaacaaaggg tgagaacaaa  28920 

gtctggatcg atcgatctct ctgcccgagc atcgacatcc actccaccgt agcgggccac  28980 

gagcgccacc accctgtcac cgtgcgccgc caaccccgcc gacgtgtgcc gctgtcggag  29040 

agtgaactcc tagagcaggg gactaaaggg gccccctttc agttcggcca ggggcagcgg  29100 

gtgagaatcg agggttggta gaaagagggg tcgggcctct cgagaacaat gagagaaaat  29160 

agatttatac aggttccggc cgctgagaag cataacaccc tactcctgtg tgtgtttgat  29220 

ttgtgaggag gcgcatgtac ttgttggatc tatccgagag tcatcctcca cttcttcact  29280 

aggcctggac ctccttttat acctcaaggg gttaccacag tggcccaaac gatctaccta  29340 

gggaagaagg aagacatcat ttacttttat tacacgtctt atttctctga caaaggaaat  29400 

catgccttcg gcgctccagc atggctgtat caaatcacaa caggaaacac gggggacgag  29460 

tgcgtcattt cccattaacc atctaaagac tttgggtacc cgttcccacc aaggaatgga  29520 

taccctaatt taaattagag tgggatattg tccccgactt gcacacgggg cgcgatttct  29580 

ctcatcatga tgatgtgacc agtcggcatc ggccacacgc cgcctgacaa agggccagtg  29640 

cgcaggcgca ctcaccctat cacaccggtc actcaagcgt cacttagcct gtcaaccact  29700 

cctgcacttc gcattaaatg cggcgtggcg gggctgcagc tcctgcctta agtgttgtta  29760 

gttgcacgct aggcgtgccc acctaacccg cgcatgttgg caggtgcatg cagggggtca  29820 

tgacggcctg accaccgact gggagggggc agctgtcact ccaccccggt ccgactcccc  29880 

tcgggggcaa tgccacgtgg tcctgacgac ggcttcctcc ctctagtcat gatacccatg  29940 

ggcccatatc accgagagcc accaaccccg cccccaacgc cgaggagtgc caccgccaag  30000 

caccaccact tccgccgccg ccgagcgcca ccaccgatgc ccccaccgcc acagttctca  30060 

gaatcaacaa tgtccaactc cagtgcttgt aattgttcct cctggcatgt aacccttgtc  30120 

ttctggaatg ccttaagaga ccacttgctg gaactcggca ccgaaatctg ctttgatagg  30180 

agatgcaaag ttgattcgag ctaggccggt gttggcgatc ggtggcggtg ctcggcggcg  30240 

gggtggcggt gctctcctag tcctggagct agggcgcgct cggcagtgga ggcggtaggg  30300 

gcattgagct aggccgacgg cggtgctcgg cggcggggtg gtggcgctcg gcggtggggc  30360 

atcgagctgg ggcagcggcg gtgcttggtg gcggcgctca gcagcggggt tgtggcgctc  30420 

cggcagcggt gctcggtggc actcggcggt agggtggtgg cactcagcgt tggaggcgga  30480 

gtatgccagt cactggcgga ggtgctctgg agagatcgat cgatccagag aagagaaaac  30540 

ctctcctttt gttctgacat gtggcccagg ggcaaaacgg tccacaaagc ttgaaaaaaa  30600 

atacaaatgg gattaagaaa tgagaaatat ataaaacaga gaaaatgtta ccaaatagac  30660 

taattagtag tcctaatgac atattataga gggcatgcga attgggtagt aaatactcta  30720 

aattctcccg atttaggtca tgtttagttc gtgaacaaaa aattttggca tgacacatcg  30780 

gatatacgga cacacatttg aagtattaag tgtagaccaa taacaaaaca aattacagat  30840 

tccgcctgga aactacgaga caaatttact aagcctaatt aattcgtcat tagcaaatat  30900 

ttactgtagc accacattat caaatcatgg cgcgattaga cttaaaagat ttgtctctca  30960 

atttccgtta gaactatgta attttttttt gtccacattt aatactttat gtatttatct  31020 

aaatattcga tgtgatgggt gaaaagtttt tttttaacta aacaaggcct gatgcaggca  31080 

ggcggcagcc gttaaaaaaa aaatgcaaga ggggtttgga tggggctaaa acgttatagc  31140 

ccctgtcgac tagggttgca gttaggtgaa cctcaccact gcagcaaatt ggcatgtcat  31200 

gttagcacac gaagtgggtt gcaggggaca tggtgcggag agcttgaagc gaggttcagc  31260 

agcgaagcaa tggcaggctc gagtgggagc acagcacggt aggcgtctca aatatccaag  31320 

taagttaaaa cctttgcatc tcttattcaa tgcagggaaa aaaactccac ttaattactc  31380 

gcctgctgtt atttgtgatt ctggttcaga ggccggtgga tttcatggag cgagaacaat  31440 

ccatctcgga ggttcctagc tatcttgtgc aagggctcgg gtgagtagtt tgtgaatgtc  31500 

atttggtcga ttactttaat gtttgaacca ttttgacttg ggtcgagttt agttccaacc  31560 

ttttttcaaa cttctaactt ttccatcaca tcaaaacttt tctacacaca caaacttcca  31620 

atttttccat catatcgttc caattttaac aaaactttta attttaacgt gaactaaaca  31680 

cacccttggt tgtttcattt ttgaatgagc aaaatgatgg atgcaatatc tggtagtgat  31740 

atgaaccggt gacaacgccg tatttgtcta cactgttcat gatttttttt ttgaggaacc  31800 

gacgacagga gtttctcctg ccggaattta tagaagaaga gaatcggccc agttaataag  31860 

agaaaccggg cccaaaaacc aaacaagcac ggttaattaa atgggaaacc ggcgaaaacc  31920 

tatacagaaa aggaaaagaa aacaactatt gagacctcac aaaagtcatc gttgccgagc  31980 

ttgcccaagg caagcagctt cgacaacata atgcacgagg tctccagaac caccaaacat  32040 

cctctagcgg agcagaaacc ttctgagcga agccttcgac aagggaacaa catcaataat  32100 

gctgtcaacg cccgttccaa aaggaaccca gttttcacct gaagggagag agagccatca  32160 

tgatgatacc tccaaggagg aaacggcacc cacaagcgtt gatatcatca acctagaaaa  32220 

acactaggca aggttttcac ccgagactct ctcaaattgc tccaccacca aaccctcatc  32280 

gtgttgcctg gacgtctgtt gagggtcatc gttgccgagc ttgcaagaca agcagctccg  32340 

actctgcctc aacagtcaat cacattgcag ctcgaccaga gatcacctca cacacaggaa  32400 

cccaactgca gcaaacctac ggcgcggccg acgaccagtg agacaggacg ccggaaacca  32460 

actccacccg ccacccctac cacacaaagg agctccccgg caatgactgg aaacagctta  32520 

gcctaagaag ggaggaggac ctaagaagag ggcagcggac gccacaccgc cggtgagcac  32580 

tggaagacga acaactaaag aagaggggaa ccggatctgg agaaatagga gtgagggaga  32640 

tggaggcgcc gtccccgtcg ccggcaaaat cgcagcaggt cggcagcccc cagctaggtc  32700 

agcggcagcc ggcgccggag cgcgccaccg agagccggac tggagccgcc gccgacgaat  32760 

gcgagccgcc gccgacccga tgccgtggtc gccgacgagc ccacgccgga gaagcccgtc  32820 

accggtccat ccgcctacgc ccgagcggcg tcggagtcga ccaagcccgt caccggtcac  32880 

cccggccaga ggggcaaccg gatctggcga ctccgtcgcc tgtcccgtcg ccggagccga  32940 

ccgccacggg gagccccacc gccgcgccac cgtcgcggtg gagagcccca ccgccgcgca  33000 

gtcccatcgc cacgacctcg ccgtcccgct gccatcgtcg ccacgcccgc gccgggacga  33060 

gacggagcgg aggatgatgg ccccgccgcc gccatcccag cgcgtcgccc ggctttgccg  33120 

tcaacgagct ccggcggcgg cgaagcacgg aggagggagg aggaggggtg gcggcggcta  33180 

gggtttcgcc cccgagcagc cgcgcgaggg cgacgcgagg gctgttttgg atttcccttc  33240 

cactgttcat gatttgaaga tagagaactc taaaataaga gcatcccttg tcaatgctag  33300 

agttgagatt gatcaactta tcgttgcgcg cagtgtacac gaagcacagt gcagaagggg  33360 

cgcgtctagt atacgaatgt tcgcgtagca tgaacacaat agagggtaaa ttccgacaag  33420 

tccagtccgt gtgcgtgggc accttttact ttcgaccgac gtgctagctg gctcgttcgc  33480 

ttgcagccca atagatacaa cccacaatat tttagcctaa ttcatttgtg tgtataaact  33540 

ttgtaggcat atactatata cctatagact ttgcacatat aaaatttata ccatagaaaa  33600 

aatagtgtag ggattttacg cacataaaca catttagtat gcaaacttta caccatggaa  33660 

aaatttgctg tagcaatttt acacatagaa acaattagta tacaaattta tacacataat  33720 

tttctttgag agaaatacac ggaaatattt ggtatagaaa ttttatattt gcatggtcca  33780 

tgttttcttg ctacagcgta gatgcccttc atttgaatta ggtccaagcc catcataaga  33840 

gtaaaaaaga agaaagtctg gcctcaatga gacaggcttg gtccgaaaaa catatgggtc  33900 

cacatactta aaaaatatta aagaactaaa cacggcctgt gtagtgatgt tatttgctct  33960 

gttgcttaga gcaggtataa taagtcctaa tcagcaggct gaagcagtgg cgaagccacc  34020 

gtaggggcca gggagggcca acacccccct aacctctatg tgacctcccc tcccctctct  34080 

tctcccaagg atgattagca cttataatct agctattaat tatatcatta gttgcagatg  34140 

agactaacta tataggacag gacaactgcc tagctatata tatatatgac tcatgaaatg  34200 

acttagctaa atgatttatc attttagaag tgattgcaag actccaatta atgaaacaaa  34260 

ctgttcaatc atccatatat taaaaatatt actgaatttt aaattggcaa atcatgatat  34320 

atgggttctt gttctctctt gtagctaatc gctgtaatat gtatgatatc gagttaccga  34380 

tcatacatca acgctataaa atcactgttc actaaacctt aagtgagttg ccatgtctcg  34440 

tagatggcac cctccatctc taaatcttgg cttcgccact gggctgaagg gtttgccatg  34500 

tcatcaaaat cctaggtgga ggagtgagaa gagaagagag agaatgaagc gggcggctcc  34560 

tctatcgctc ggttgaagcg catcgtccga gaaaaatctc tcgctttcca gcccggtgcg  34620 

agcgctaagg gcacccacaa tggttatcta taggctctct acaagagatc catgtcagca  34680 

tattttccta catggaagat attaaatgaa gagagagagc aaaactatct actaaattag  34740 

agatggtcta tagagaaaaa cgaggcaatg catgagagag atatagatac ccatgtagac  34800 

atactattga gatggtttac tattaatcta gtctattgct gagatgtaca tgttttatag  34860 

atagcacctt actttaccat tgcgggtgct ctaagggcac ccacaatggt tatctatggg  34920 

ctctctacaa gagatccatg tcagcatatt ttcttacttg gaagagattc aatgaagaga  34980 

gagagcaaag ctatctacta atctggagat agtctataga gaaaaacgag gcaatgcatt  35040 

agagagctat agatacccat atagacatac cattaaagtg gtttactatt aatctagtct  35100 

attgctgaga tgtacatatt ttatagatag caccttactt tactattgcg ggtgctctaa  35160 

gccgctgctt tgttcctccc tccgatccca tgcatctctg ccgccgccct cttccctagc  35220 

tcgcctcctc tacgcggaaa attgccccag cctccctcca aatcgagtcc cccctgctac  35280 

aattcatagt ataaaacact caaatccatc cccatgccac caaattcgtc ctcaaattgc  35340 

ctcctccaaa ccatagacgc catttgtccc caaaccatag caaccacagc aaggttgaac  35400 

ggcaaagcaa gaggacgttt gtaccagcgt ctctggaggt ctcgccgccg gcgactcagc  35460 

ccgtcacgcc gccgccacct cagatcgtcc tactgccatc cttcctttca catacagatc  35520 

tagagactgg agccaggttt cccccagcaa caccacagtc catgagcatg tgtatcttgt  35580 

ttgatgaaat agccacaata gatcatatct catgcatgca ttaaatgcct aaatatttat  35640 

caaaggtaga ttaaccacca acctatcagc cggcctatta tataagtgaa ggctttaggt  35700 

gatgtgtcac tagtataacg cccactgctg gcgttcttat tatccttgct cttatctggt  35760 

tcaggctaga tcgatatgga tattctgttt gcctcgcctt ttgtgttatc tgaaatttat  35820 

atggcacagg aatgatcttt tgttgtgtat gtatgtttgt tcaaaatctt aaatgaatgg  35880 

aatgaattat cccttcagca ttttgtggtt agtattttaa tttcgatgag atgaatgacc  35940 

aactgtaata tttgtcatat tgaatatttt gtgagactgt cagttatgtc gtgaaaattg  36000 

ccatccataa tatatgtcag attgacaact gtcactgtca actcatagta aaaaaaaaaa  36060 

tcagatcgga ccgaccgttc aactggaaaa aaatcgaaac caaagatctt caaggttcgg  36120 

ttcgaatgta agaccggaca tacatgtaaa actaccttga accggctatt aaaccagcac  36180 

cgattaaacc tgatgaggcc acaacagtcg tttaatggcc ttaatgtggc ccaattagtc  36240 

tgccatgcac actcagttgg caaaaaatga aaaaaatata tcctcacatg aatccggctg  36300 

tcctagcagt tgcgttatag ctttaacata tattatatat aaaaattgaa ccgcggttca  36360 

accacctggt gctcgattca tagtttgacc agcggacccc gtaaacccag gtgcccgatt  36420 

catggttttt cgtactatac cggcaagcaa acaattggct gtcttcggct gcccctcttc  36480 

ctaatccctc ctctcgtttt ctatgcgcga gcttttcaaa ctgttaaacg gtgtattttt  36540 

ttaaaatgtt tatatacgaa agttgcttaa aaaatcaaat taatctattt ttttaaaaat  36600 

attagctaat acttaattaa tcacgtgcta ataaaccgtt ccgttttccg tacgtacacc  36660 

ggtagggaag caatggtgaa cacagcccta aacaggtcaa cctcaggtgt tgactagagt  36720 

actagacagg tcaaaagggt ggccccaccg caccacccaa cggaatgccc aattgctcac  36780 

cgaaacagca gcagtcacaa cctgtccacg cgtttatccc ccgtggacac ggtccacgct  36840 

ctaaatgaca ataccttagc cttggagtct ctcattgcac gtgagaggag tgcatacacc  36900 

gcgtccacgc ccacattcac acgccccccg gtaattcctc gtccctacta cagtactacc  36960 

agtagtaaaa ctttcctgcg tctcctcccg tccaatggcg actccaccgg cggccggggc  37020 

gccgcgccgg cggtggtgcg cgatccaggg tctcgtcgtg ttgttcctcg tctacgtgct  37080 

tgcggtgctt gtgctcgccg gcggcgagct cttccacgac gaccagctcc agccccgctt  37140 

cccatgtacg tgctcccggc cggattcctg gtttatcttt tttttttccc ccacgtttaa  37200 

ttttttcccc ctttttttct ctcttccgtt ctgcaagatt ggttcgtgat ttccacgcgt  37260 

ttctgatctg tgtagcctct cctggaatcg gatcctcttc ctcctcctcc tccgctcgaa  37320 

ttctcctctc gcctcgctcg atgatccgcc gtctcgggga gatcgctcgc cgtggtggaa  37380 

gcaggcggtg gtggactggt ggtgttcgac cggaatcggg ctctccaaga agcgagggag  37440 

gaaacagttc agccacggat caggcgtgtt cgcggcggtg cgccgcctcc ggcctggcgg  37500 

ggatggcgct gcgcctcgcc gagcgtctgt ccttggagga ggacagcgtc ggcggcggca  37560 

acctcgtgtt ctcgccgctg tccatctact ccgcgctcac cgtggtcacc gccggcgcgc  37620 

gggggaccac cctggccgag ctgctcgccg ccctcggcgc gccgtcctcc cgcgacgcgc  37680 

tcgccgagga cgccggcgag atcgtgcgcg ccctccccgg cggctccggc acggcgacgg  37740 

gcgggccccg cgtcgcgcac gcgtgcggcc tctggcacga tcggaggagg aacgtcaagc  37800 

cggccttccg cgacgccacc gccgcgtcct tccaaggcac gacgcgcgcc gtcgacttcc  37860 

tcgccaacgt aagtgatcga atcatcgatc tatatcaatc taatgtcacg ccattaacga  37920 

atgacgatct ccattgaaac ggacatgcgc gacgcgtgta gccggaggaa gcgaggaacg  37980 

cgatcaacag ctgggtcgcg gcggcgacgg agaacctcat cgacacgatc ctcccgccgg  38040 

ggtcggtgag cacggacacg cggctcgtgg tcgccagcgc catctacttc aacgccactt  38100 

ggcagacgcc attccgcaag caggacacca agaaggacaa gttccacctc ctcggcggcg  38160 

gcggcgacgt cgacgcggac ttcatgcgca gcggcgacga ccagtacgtc gccgcgtacg  38220 

acgggttcaa ggtgctcagg atgccgtaca acacgcgtgc ctcccgtacg cacacgcaac  38280 

cgcagtactc gttgtgtgtc ttcctccccg acgagcgcga cgggctgtgg accctcgccg  38340 

acaggatgga ggccggcggc ggcgaggtct tcctccggga gcacatgccg gagaagcgcg  38400 

tcaaggtcgg cgagttcagg atccccaggt tcaagctctc cttcgacggc agcatcaaga  38460 

ccgcgctcca gggtgtcggg gtcagggccg tgttcgatcc ggcagcggcc gacctgtccg  38520 

acgtgctgga ggagggcaac tccggcgatc cgccgctgtt cgtgtcggac gtcctgcatg  38580 

gggcagcgat cgaggtgaac gaggagggca cggaggtggc ggcggccacg gtggttatta  38640 

tgaaagggag ggcgaggcgg ccatctccgg cgccggcgcc ggtggacttc gtcgccgacc  38700 

atccgttcgc cttctttgta gtggaggagt cgtcgggtgc ggtgctcttc gccggccacg  38760 

tcgttgaccc cactaatcct agtcaactgt aatgaaattt gcatggatct taaatggtcg  38820 

tggcaactag agagcaaatt gagcctttta ttcgttttaa attggatatc taccctatag  38880 

tatgaattta aactggctag ttctacgttt gctatatttt agggtgaatg aaatagaaaa  38940 

ttgctttggg tgtgttcgga cctctagttt cccaacccaa atcccttgtt tttcgcgcgc  39000 

acgcttttca aactgctaaa cggtgcattt gttataaaaa gtttctatac gaaagttgct  39060 

taaaaaaaca aattaatcta ttttttttaa aaaaaattag ctaatactta attaatcacg  39120 

tgctaataga tcgttctgtt ttccgtgtgg aggcactatg ttcccatcat ccacatgcta  39180 

ggcattcata tagacatgag aagacggctc actcagatct actggatcag caagaaggcg  39240 

ctggcttcag ttgagagtac tggagctgtg tgcttttagt gagggaaaat ctattcaggt  39300 

ttcagcgaaa cgtttaagca gttttacatt aacgccgtgt ttagttgcaa attattcttc  39360 

aaactttcaa ttttttcatc acatcaaaat ttttctacac acacaaactt tcaacttttc  39420 

cgttacatcg ttccaatttc aaccaaaatt ccaattttgg tgtgaactaa acacagtcta  39480 

agatgctgct ctttctagtg atatttgtac tggtcatcga agtcgttcac ataggattgg  39540 

ttgaggtgat tgtaattgtc aaatgtgctg tcgtgcaaca aaaataaagg attacattcg  39600 

agatggaaat ttttgcttgt gtacataata gagcaagagt acagtagcat gctccgccgc  39660 

tggatctggg agggagggag gggccgggag ccgccgccac cctcctccgc cgccgctcgc  39720 

cgccaccctc cgcctcccgc cggtagccgc cgccctccac tgccgccgta cgcgtggcca  39780 

ccgccttccc cccgcccccc tcaggccaga tctgggagag agtgagggag gggagtgccg  39840 

ccggccaccg ccctccgccg ccgcctccac cggtagccgc cgccctccgc tgccatcagc  39900 

gccggggaga ggaggagagg tgcggggagg ggagaggtga ggcaaagagg acttagaaaa  39960 

aaatctaggg tatacagcct ctatttatat ttcctatgta ttttcgcagg cggaggtccg  40020 

cctgcaaaaa tgaagggtat ttttgcagga agaccgttta agtggtccac atgcaaaaat  40080 

ggattttcgc aggcgggcag cgggtttcac cccgatttac attttcgtag acggctattt  40140 

gtatccgaag gttatgtcca cctgcgaaaa taagtatcca acatcggcaa aaatgccttt  40200 

tcttgtagtg taatagagat gcgacatatc ctaagactat aaatttggag agatagttat  40260 

ctagatttat agttatataa tatattacat ttgtattagg ttgcatttat attccagagg  40320 

gagtaatagc tgccctatgt ggcaagtgga tcagtagatc aattggcatc aaacaatatt  40380 

ggtgtgcaat ctttcgatca ttggttgttt ttttagaaaa caaaaatatt ttcggactgg  40440 

cttgaatgct ttcaaaacat gtaattgaac actcgccatc gagtcagaaa atcgttttca  40500 

atctactaat tgatcggtta actaggtcct gtcatcgtga agcaacataa tgcaatctaa  40560 

taatctgtac acaagtcgaa ggaagcatgt aactaagcaa caagaagctg catatacatc  40620 

atggagtagt acgcacgaat ccaggtcaat tggcaaacta cacatttggc gcggcgaccc  40680 

tgaatctgaa ttgaacccat cataggcctg cctcatcaaa ctggttcggg cgggagagtc  40740 

tcagtagcac ctgaggtcct gggtttgact ccccgtggga gcgaattttt caggatttaa  40800 

cggcattgtg ctttcagtgg taggcgacgt acccgtcgac agcgaggcgc ccgtggtgac  40860 

ttcgtcaatc tctccaagat ttgccagtcc agtcttcgaa gatgctcata gatatagggt  40920 

ttgcgtgcgc gtgttcatag gggtcagtgc gcgtgcgttg tgagtatctg cgttgtactg  40980 

tgtaattttt ttttaaaaaa aaaactggtt cgggcagggc cccgtacgtg gacctcgacg  41040 

cctcgagcgc cctctgcatc tttccaaaac cctacaagtt tgaggcggcg atcgatcgga  41100 

caggcagcgg ggagacagat cgagcgagcg gtaggcatat gggttttagg tcgttgtcgc  41160 

tgctgggctc tctcgttcgc gggagtatcc gctgttcctc ctcctcgccg ggatcgggaa  41220 

tcgctaatcg tctactatcc ctggtaaatc aaactcagaa acttttaact aataattata  41280 

ttaatcataa tacatgatat atcgctagat tcatattttc actctaattt caaattcgtt  41340 

aataacgcaa catgaataaa ccaatagtca aaatatgcca ttgaaaatcg tgtaaaaaat  41400 

atagatatta taatttgaga cggagggagt agtaatctgc ttcttttgat cttttctcat  41460 

ctcagatcta tacatcgtat gctttctccg ctagcggctc ataattattc tcgcagagga  41520 

acgcgctgtt cttctactcc gatgcccgtc gtaagagtct tgtggcggcc aacacctctg  41580 

ctttcgccgc cagatcatcc cgttgtctgc acagcatggt aaatttcttt caaatcttgc  41640 

tgtgtgtgtt tccctccttt ttcaatccca cagacacaca cattcacgcg cgtgtttcca  41700 

tcttgctccc gttatttcgt tcgttaattc atcgttgtgc aggggtctct ggggtcgccg  41760 

gcggggagga gagcacgccg gttccacgac ttggtaaatt tccttcatcg tttatctatc  41820 

taagccttgt tttacttcca gataagctca cgttgaatcc tcgtggtgca gagggatgtg  41880 

gtcttggaac atgccgatgc tgctaccgct acgttgtctg ttgttgtttt ctctgcggtt  41940 

gctggaattt tgcatttgat gcaagataca ggtgagtttt taggtactcc atgtgaaact  42000 

agctgccttt gactgcatgt ttcatatatg agctttgttc tggtccagca gttggtacct  42060 

ccaggtactg gtaccacagg taccaaacga aatccggccg ttcaataaac tggggtacga  42120 

ttggaaatga agtaaagcag ccagctagcg tgcgacgacg aaatctcctc atcttcacag  42180 

gcatatccga gtcgccgctg ccgtcgcatt ctgctctcct tgacgcatga catcgttcct  42240 

cagctcgctc cgtcgcgcac gtctctgtca ccgccgtcgc tgctgcctgt cctcccccca  42300 

gccccagcgt gtccttgctc tgcggcaacg acagtgggac cgatggccga cgctgccgca  42360 

acatgtatcc tgacgcgccg gactttgtcg ccaccgccgc tgtagtctgc accctataat  42420 

tgttccggaa tggaggttgt gttggagctt ttcgcatgag tattgatttt gtgtttgtct  42480 

gacaaatcaa cctgaagcca tttaggcaaa tcaacttcat gcttctcttt ttttttgcgg  42540 

ggaacttcct gcttctcaat ttattcctgt atgtatcttt cttgctcaaa aactgttcaa  42600 

ccaaatcaac catcgtcgtc gctagcaatg acccgtggag tgatgccgtc gtcgccgaag  42660 

acaattatcg gagcgctgcc accgcagttg cagatgatcc ctggagcacc gccgtcactg  42720 

ccgataactc ctggaatgct gccgttgtcg ccgctgacaa caactcctgg agcaccgttg  42780 

tggcctcaga agactggtgg agcgcaccgt aattcctgaa gcgtcgccgg ctcgccgcca  42840 

ctgccgtaga ttttcctctg caaagcctta tccaaaacac gaatcaaatc gacgaaattc  42900 

ctttccaatg tgcaaataca attttacccc tccacctcat tcccctttgg caggtaccac  42960 

gtagggagta aatggtactt gaaggtacca attgatgtca gccatccgat catacctatc  43020 

cagcggtcca catttggtac cgggcttcac tgctggacag taaaaaaact cttcatatat  43080 

aaccatcaat ggttatggga aattatttcg atcgcataag aatgtaccct cgtttgctta  43140 

aaagtcatcc aaattgttat gaaaaattct ggaaaatttt gacaacactc atacaaaata  43200 

tctatacaac tttataaaat cttggctcca aactcaagtc acacgtcgac gtataagaaa  43260 

gacaaattca gtgtatgaat agcaatgtac tgttcacgtc taattttgtc ttttcgatgt  43320 

gtagattgaa tttgaacttg atttttaatg gaccgataca tatcactgta ctctacattg  43380 

tcgatatttt tttcagattt tttcacaact atttgtatcg aattttgaaa aaaaaagcac  43440 

acacgaaggg ataacccctc aagagattag aacccactcc tcatactaca tgttaaacac  43500 

ccttcagatt tctcgtcttt agctttcctt ttatgttttt cgccgggaag ctttcctttt  43560 

atgttacatt gccctcaacc ctcacgagtt catactgtct gtacgtagac gaagctcgga  43620 

aggaggacac acccactaag acaaatcctt acttccgttc caaccagttg atggaagact  43680 

tgatacgaga gagggcgtct tacaacgaaa caacgcctga cgagaagacc gtggttcgag  43740 

agtacatgga ggatgatcaa gacataaggg caaggttcaa ggattggatg aaggagcatg  43800 

gcaggacata caagcaggac gaggtggagg aggctaggcg attcaaaata ttcaagtcag  43860 

ttgcaagatt ttctgatgca gccaacgatg attctgccaa cgcagggcac tcgacccgtt  43920 

ttggcctgaa tgagttttca gactggaacc aggaagaact tgctcggatg tgttgttgta  43980 

tgccagctag gagtgatggt gggtacttcg aaatggtcct gtcttatctt gttccgcagg  44040 

ggatctggca tcaggtatag ctgacatgga gtacaaggta tgtattccca atttcatcta  44100 

tacaatgtat attttaattt gtttttctga tagacatgga tcgagtgcat taactggaga  44160 

agcccttagc ttgatctgtc ccaaaatgta acgtgttttg gaacggaggg agtagtagta  44220 

acctatcttg tacttcctgt gactcttttt tggaatcggc aaattaagtg ttaattattt  44280 

ctcagttggc ttctcactcg tgaagcagtt agtgtactgg cttgaccttg aattccatgt  44340 

tgtgatagga tcagggttgt tttaaatctc cgactatagc tgccgctatg tccggttata  44400 

tctgtttgag aagagtttta gctcttttct cttccgtata atttagccgc tatagatgcc  44460 

cctataactg ttgagagggc caaccgctaa attagcctgc tataaaacaa tggttaggat  44520 

gaataagaaa tgcatttttg aactacctaa ttattatctg cgctagtttt acttaaagag  44580 

aaatatttgt gtactgatta gtaaataccc cgatcatata tatcttggat actggcagtt  44640 

tagttttgtt atttctatcg tgtggcggct tcacaatcat gagttctcaa ttgttgattg  44700 

cttgctgtat tgatcgcttg ctaagcactt gtaaagtagt ttgattttga cacagaaatg  44760 

gcctttattc aggctagcta acgtcaatca tgtttgttga caaatcaaat actccctata  44820 

aatgcaattt cataaatatg gtatcaactt tgcactttga tgcttacggt tctgtgtatt  44880 

tttttcttga agcaaagtag ttggagaatt gttttgtttt ccttttcagc caaaaacggt  44940 

tttctattca agtctctgtt tttctgtaat caatggatct tattaagctc ttcattgaga  45000 

aactctaggg tggtggacct taagaagtga attttctctc acaggctaac agctacagcg  45060 

cataaaccag ctatagtttc tgtaagttgt catgatttat gttcatgtaa tggtacagta  45120 

gcagtgtgaa tgttgattta cagcagcctg accgtatcga aaagtaacat aaattgggtg  45180 

caatgtagag ttttaaccat tttcctggga caaaaaaaaa tttatacaaa attgccttgc  45240 

tcaaatctga tactttattt ttgctttaat ttgtatgctc gctggttgca cctttgattc  45300 

ttcgtctgtg tacttctctt tcattatggg gcttcttcag agctatagcc tgcattctaa  45360 

ttaatttcct ttctcaaaag caggagtttt aagattgaga agggtcgaga cgctatatat  45420 

atatatatat atcatacgaa gaccaacaag ctgtcatgtg aaaaccagcc aaaatgaatc  45480 

tgtttcagat gtcaaatgtc catatcttcc gtttttgtac cctctaatgc tacctgtctg  45540 

aatagcataa tgctagagtt gttatggtta tatgagctat cttgtaaggg tggtagatgt  45600 

tgaagttaat ataaatggga atttctgaag ctaattaaga gtttgttttc ccattggaca  45660 

attgcattct tgtcctaact ttgatgatca aactctatat cacacaatac tgaaagttac  45720 

agtcgcgtgt actgtcacac cgagtcgttc cctcgctggt ggattaatat ccccaacacc  45780 

aacgatctag gctccagaat acgttcccat acgttatgcc aagttctttg atcggtagtt  45840 

ggaatatatc tcttgttcaa ctaattctaa actctatcaa acatttgttg tcctagtata  45900 

tttcgggtat tctcatgtga ttcccacaag ctcaaattta ttccattgtc atgtcatgcc  45960 

tagttttcca tttgttcttc aaaataatga aagaaaataa ccgacctaca aaactcatgc  46020 

tcaatccaat caagttactc gtcgtgtcgt catgcttttt ttggccaaac tcccttcgaa  46080 

gaagaatctg tcaccagaga gactaaaaca ataaaataag ttgatccccg tgatgggcct  46140 

atctgaggca tcattccttc gtcttggggc cctcacattc taggcctcat caaattaact  46200 

agtttggtgt accgcgcaaa tgtccaacct ttttaaggcc gctcgtaata tagacgctat  46260 

ccttgccctc gaacccccgc atccttccaa accctagcgg catgtttgcc aagagaagag  46320 

gattgggggt ttgaaaggag gaagttgatg gagggattgg tcttgggagt tccattttta  46380 

ctccccgtac attatttggg tagtagagat gacaattatg gcgagtttgg gtataaatta  46440 

aattttacgt gatgatgtat ggccgagatc tatctcttac agttagaagg aaataggtgt  46500 

cggttttaaa taaactgaca cctataggat attaggtgtt ttctagtagt gcacccttct  46560 

tagcggtgcc actcctggtt gtagctttct ttgcacgtct tccgacatca gcaaaatgga  46620 

ccacaattca atgaaaaaca tactttatgt attagctcag tagggtcatg agatttcttg  46680 

tttttaaaac atgctgcatt tttggctttc catatggtct agatcacagc tgcaatctcc  46740 

acttccatag agggaatatg agctagatga ttacggcctg ttttggaagt gatttcgtca  46800 

tcgtcgatcg tctgcatttt ttttccttcg atggtgacaa cattgagttt agatcagggg  46860 

gctagagcgt cgagcttcct acaacaatca tttgtgtcta tttcactctc ttcgtcgtcg  46920 

ctggcaatag cgttctaagc ttgggctact tcgttgttgt cacgccccac cctatcgcac  46980 

agccaccacc aaggagggtg tgccgcagga gacagtatgc cattctcacg cataaccatg  47040 

ataatgttac ccactataac aacataaatt tttatagtac caataaaaaa ttataaatta  47100 

attattggac tgctaagagc aggtacaata gatgaatttt gcccgcgata ctacatgcat  47160 

gcagcctaat atggtgagtt ggcagagaaa tttggggaga aagagggtga gccggcgact  47220 

aattagtcac cgcctccacg cgtgtgtcga ggcaagaaaa gcaacatcat acgttttcct  47280 

actggaccat acagttgtgg ggtccacgtg attagtagta tgtggatgag aagatgacat  47340 

gtgtagacat gacactataa aaaaaagaaa agaaatgttt tgtcattgag tggaggcagc  47400 

ttgtagacta ttgttgtaca aattagctat ttggtgaaag agtattttat tatacttgtc  47460 

atgatttgga gctgacagct tactcctcta ttaaacttga tctaatagga tacatttata  47520 

cttttaggtt gcaattggtt gcaaattcag gtagatcggg aagtatagct tttattcttt  47580 

ggattgcagg atttgaggcc tgcccctttt ttctactcca tcagtttcat attataagtc  47640 

attttgattt ttttcctaat aaaacttttt taaagtttaa ccaaatttat agaaaaatat  47700 

agtagcattt tcaacacaaa atatatatat tatcaaaatc tattaaatct ttcatctgat  47760 

gaaactaatt tggttttata catgttacta aaattttcta taaacttgat taaatctaaa  47820 

aaaatttgat taaaaaaagt aaaaacaaca tataattaaa taatgggggt actaataata  47880 

gataggtttt aaaccatggc gatttcatgc tatatatacg aaattgctaa aaaaactgtc  47940 

gcaagtttaa ctataatgta attacagtat aatgtaatta cagtatagtt acattgtaaa  48000 

ttacgctgta actatatagt tacattgtat ctgcactgta agtatattgt aatatctata  48060 

taagttagat ataaaactgt atatattatt ttaatactta tataaaagtt atataatagt  48120 

tatagtggaa tcatattaca attatactat aattaaagtt tttttcttaa agaacttagg  48180 

gcagtttttt aatagtccct aacaatatac gatatactat gggcctgttc actttgatgc  48240 

catttttaat cttaccaaat tttggtaaag ttgtcaaaaa agtggctaca tttagtttac  48300 

tgccaaattt tgaagatcta tctatataac acccgacaga tttttgttat aaatcacaca  48360 

gatttttcta accaccaaac ggccaacttg ctagccaaat taaaaagcaa cgcctatagt  48420 

gtagattaag gcgtgttaat ccaagccaca aaactaacta cttgtcagca catatactaa  48480 

aggctttttt taaaaaaaat tacaccctaa ttacactata cttacatttg taactatagt  48540 

gtaattatag tataactaat atgtaagtac tgtgtaacta atatataatt atagtgtaac  48600 

tacactaaaa agttttttta aaaaattaca ccctagttac actatactta cacttgtaac  48660 

tatagtgtaa ttatagtgta actacaccaa aatctttctt ttaaaaaaat tacaccctaa  48720 

ttatactgta cttacgaatg taactatagt gtaattatag tgtaactaca ccagaatctt  48780 

tcttttaaaa aaattacacc ctagttatac tgtacttacg aatgtaacta cagtgtaatt  48840 

gtagtgtaac taatatgaaa ttaatacact agtggagaaa ccctttgtag tcccggttcg  48900 

taaccccctt tagtcccggt ttccaaaccg ggagtaccaa tccgggacta aagatcgcta  48960 

tctttagtcc cgggtgaaat aaccgggact aaagatcgag ctgacctttt ttttttgcat  49020 

ggccctgttg ctgcatggtt tatatatata tatatatata tatatatata tatatatata  49080 

tatatatata tatatatata taaaaaccat gcatatatat gtttcaatac atatatatgc  49140 

atacatatat atatgtatat atatatatat attatattat atgtatatac atgcataata  49200 

tatatgtatt tatacatata tatgttatgc aaatgcatat gtatatagat atatatatga  49260 

ccaaaatata tttacattat agaaaatgtg tacacatgca tatagaaaca tatgtagtca  49320 

tatattaatt acaatccatt ttatgtccta gctagctacg atttcgacgt agtagtagtc  49380 

gctgctagct cagaagctaa ggaccggtga attgtgtttc cgtcgtagta gaattcaccc  49440 

ttgggatcaa ggatatcttc gttgatgaat cccatgagtt gttcttgaac cgctgcgata  49500 

aattccttgt gtgtggtcag gttatccctc atgcgaataa actatatgaa tgtatgaaat  49560 

tgattagtaa ttaaacaaga aatcgttacg taatgaaatt ttgaatttat ttgtacgtac  49620 

atcgagctct cttgtggtga tgatttggtc tgtaaggcag tggcaatact cacacacgta  49680 

gtagccgcac aagttagttc cctgcttttg ctttgcgcac tacaaataaa tgacaaatta  49740 

acggcgtgag atctaattaa tatacagttg tatgtattaa tttgaatcgg agaaatataa  49800 

atgtagagca tgtgtactca caggaaattt gaacttccgc ctaagtcttt ctctccattt  49860 

gctgcggacc aaatgacgga accgatacca agccctacat ggagtttaaa gctatgattc  49920 

gtagtagcaa ttaacataac aagattttct taattaacaa aggaacttat gacggtacct  49980 

gtctataagt tcgaaaacct tgtcaaacgt agactctttt ttatccattg agtcatatac  50040 

gttgacggtg caggcctcca ggtcgaagag taaaagcacc cagtggaatc tgcaatgtgc  50100 

gtgggatgca ttacatatga aacacttagc aagttcgtac gggaatgaaa tttggtatgt  50160 

aggaagacag taaaattaaa ctaactctgt gttgtacggt aacagtatga acgtcttgta  50220 

atgctgcgcc ttcaggagat ggacgagatt gtcctctgtt tcctgcggat attggtcgag  50280 

cattgcaacg tttactctcc gagggtcgat gaatccagta tcgaaaaccc tccgccgtcg  50340 

ggccctttga atctccattc tacaacgata aaagggagta ttttatttta tatagtctac  50400 

ttatatacaa ggacctaatt aattaaagga gacgtagtaa ttaagaatta taattgaacg  50460 

atatacttac aaaatccagc aactcataat agagacgtcg agggcgtcca gctggtatag  50520 

ttcgtagatt cccctgaaat tgatccagag aatgtcatct ccttgcaaga agtccgtgtc  50580 

cctgatcgtc gctccgatca tctctctacc ggtggcgctc atctccatgt acagctgatg  50640 

gaacttgtac atttgtgtgg gtagggactg cagcagctca ggcttgacaa gcggtttacc  50700 

gagttcgtac atgtatttca ctttcgcctt ttcgattggt gcgactccta gcaattgatc  50760 

cgtagttaga ccggtgtcag taataaattg ttctatcgtc atttctttac tggtcaccaa  50820 

cggctcgatc tcctggtttg gttgctctcc aagctgaggg actggtttgg actttccaga  50880 

agatgctttc ttcagcgttc gctcatagtc cgatagcttg atggcctcct tgacagatgc  50940 

agacataccc ctgaagaagt tcctgacact ggggtctata ggaatcttct tttctggact  51000 

tcgaggcttg aattgtctct tgacttctga tgcaacgtaa gcgtcaagct cctcttgcgt  51060 

gcgatcgtac cccgggtcct tgttcttggc ggcgtcaact ttcgccttct tcactgccct  51120 

tgtgtgggca ggcggtggag ctgggggggc ccttgacttt gaaggtgccg gaagaggagc  51180 

ttgcggggga gtaggtgtag gagcacgagg aggagtcggt gcaggatcct gaggaggagt  51240 

cgatgctgga gcctgaggtg gagacggtgc tatcggagca tgaggaggag acggtgcagg  51300 

atcctgagga ggagatggtg cacgagacgc cgcttgtcgc ccagggagga tgatgtaccg  51360 

cctgcgtcat agaataatgg catggcttgt ttctcgtaga tgcgtctcac cgtctcctcc  51420 

agggtaatcc agctcgaggt cctcgtacgc gccttcgacc aactcaactt cgaccttcga  51480 

gtatcctgct ggaatcggcc tgcagtggta agtacctgaa gggtccgttg ggatggccat  51540 

gcccgacgcc accttcatgt tgtgagagat tatttattag taatcaacat atataagcag  51600 

caactagcgg aatggctaaa tcataccttt attgataagt tcttgaaagg aatatgcagc  51660 

tcacatggtg tccgttgagt gatgtcatca acgggacagg tcgattcgtc ctgtgtttgc  51720 

atggcgtcca tgctctgtga tcctacctgc cccgttgagg cgcagctgct acggtttcct  51780 

gacaggctta ccattgcagg aggaatggtc agctggggat catgggaccg atgtgcggcc  51840 

atgcgttcat caaccttcct tgccacctcc tcttgcatgt tgagttcgta gctcgatacc  51900 

tggaactcta ggtctgcaat cttcgcctcg gtatctctct tgctcctcat ccaactcctg  51960 

tacgtgtgga tgtcctcctt gaaaccaatc ttccaaggaa tcaccccttt ccctcgtgtt  52020 

cgtcctggat gctctggagt ctgcagggcg agtgtcagct cgtccctatc tctgtctggt  52080 

cggaacgtgc cctgagagga ggcttccact gcatctgtta gtcgtcgcgc agcctctcgt  52140 

atctgatcgc cgaagaccag tgagccatca gctgggttga gcgttccacc gtgagcatag  52200 

taccagaact tcgatcgttc cggccaattg gctgttgccg gttcgatacc cctctcaatc  52260 

aagctagcct ccatctgctc ccacttcggc atcgcgacgc tatagcctcc tgaccccaag  52320 

tggtgatggt acttcttctt ggcggcattt tctttgtttc tttccatcat cgcctgccct  52380 

tgttcacctg tcttatatgc aacaaactcg tcccagtgat cccttagctt tgggaatgtg  52440 

tcgaagttcg gtgtctgccc cttcagtata tacttttggt acagatctcc cttgaagctc  52500 

tgaaactgtt ctgccatttt cttcagagtc caccttttca ctttgtcctc tgtacccgca  52560 

ggaagggtga atgtctcgag cattgtggtc cacagcatct ctttctctga atctgggaca  52620 

aagctctcat gatctccgcg tgcccttgtt cttcgccagt acaccgtact gacaggcacg  52680 

ttatcccgca caacccaacc gctgtgacgt acatagttct tggcggcttc ggccggggca  52740 

ctaggacgtc catcttcttg cacttccgtt atgatgtgcc gaccctcaag cttcttcgct  52800 

gcacctcgtt gcccgcgtgc cctcttctgt ccaacggagg gttgactacc actagcctcc  52860 

tcctcctggt tcccctccac atccctttcc acgtgcccct gctggttccc ctccgcatcc  52920 

ctctccacgt tcccttcctc gttcaagtac tggtttggat cctcgttccc ctcttcttca  52980 

ttccagtact ggctgcttcc ctccgcgatt gtatcgtaca atatctgttc ctcatcgcgg  53040 

tcagccatct gttgatacaa gaaacatctg ctaagtcacg agacatttat gttttaacaa  53100 

tctaagtcat gtatgctaag tgtaaatgtc gtacattaga accctacaca accttacgtg  53160 

ctaagtctaa ttacaaatcg tgatataagc taagtctagg tgacgtatat tatataaccc  53220 

tagctagtaa ataattatat actaagtcta attacaaata aaataatctt atattaaaac  53280 

tcaaataata ttacatgcta agactacaat agtcatgtat atgctaagtg tttcgtgcgt  53340 

atatgctaag tctaattaag actacaatag tcaattgcta cttgtcgcac caattccgta  53400 

gtcaataatt acatactaag tctaattaca aataaagtaa tcttatatta aaactcaaat  53460 

aatattacat gctaagacta aaatagtcat gtatatgcta agtgtttcgt gcgtatatgc  53520 

taagtctaat taagactaca atagtcaatt gctacttgtc gcaccaattc cgtagtcaat  53580 

aattacatac taagtataat tacaaataaa gtaatcttat attaaaactc aaataatatt  53640 

acatgctaag actaaaatag tcatctatgc taagtgtttc gtgcgtatat gctaagtcta  53700 

attaagacta caatagtcaa ttgctacttg tcgcaccaat tccgtagtca ataattatac  53760 

atactaagtc taattacaaa taaagtaatc ttatattaaa actcaaataa tattacatgc  53820 

taagactaaa atagtcatct atgctaagtg tttcgtgcgt atatgctaag tctaattaag  53880 

actacaatag tcaattgcta cttgtcgcac caattccgta gtcaataatt atacatacta  53940 

agtctaatta caaataaagt aatcttatat taaaactcaa ataatattac atgctaagac  54000 

taaaatagtc atctatgcta agtgtttcgt gcgtatatgc taagtctaat taagactaca  54060 

atagtcaatt gctacttgtc gcaccaattc cgtagtcaat aattatacat actaagtcta  54120 

attacaaata aagtaatctt atattaaaac tcaaataata ttacatgcta agactaaaat  54180 

agtcatctat gctaagtgtt tcgtgcgtat atgctaagtc taattaagac tacaatagtc  54240 

aattgctact tgtcgcacca attccgtagt caataattat acatactaag tctaattaca  54300 

aataaagtaa tcttatatta aaactcaaat aatattagaa cactacacaa tcttatatga  54360 

taagtccaat tacaggtcta ataatcttaa ttaattgcat tacaaatata acaatcattt  54420 

atattattac gtcacttgcc tgctccaatt ccttctaggg ctagctcttc cactcaggct  54480 

tgacggacga ctccgacaac acgtcttttc tgcaagatac aaaaagatgt attaggataa  54540 

atgcgaagta acatatatat atatatatat atatatatat atattgcatt tcacgttaac  54600 

gttcgtcctc gttcgttcgc tcgttcacgt tccctagctc gttcacgttc gttcgctcat  54660 

tctcattcac gttcgttcgc ttgttctcat tcacgttcgt tccctcgttc tcgcttgtct  54720 

tcgatcgatc gttctcgttc tcgctctcat tcgttcgatc gttctcgttc tcgttcacat  54780 

tctcgcggca acgtacgttg acgtgttcgt tctcgctctc gttcgttcga tcgttctcgt  54840 

tctcgttcgt taacggcggt gtggctggca tcggggcggc ggttggcgcg gcggcdgtgg  54900 

cggcggcggc ggcggcgtgg cgacggcggc ggcggcgtgg cgttgcgggg ccgtggcggc  54960 

ggcggcgtgg cgtggcggcg gcggcattgc gcgcgcggcg gcgaaggcgg cggcggctgt  55020 

ggcgacggcg gcggcggcgt ggctgttggc atacggcggc ggtgatggca gcggcgtggc  55080 

gcgtcgtcgt cgtggtgcgt tgtcgtcgtg gcgcggcgtc tcgtggcggg cggcgcgacg  55140 

gagagagatc gatatcggag agatcgagat gcatgaaggg agatctggcg gcggcggctc  55200 

tcaccccaga gatgcggcgg cagcggagga ggcggaggcg gcggcgagga cgacggcgag  55260 

atacggcggc gtcggcgcgg ggatttgccc taggcagtgg cggcgaagga gagaggccga  55320 

gagagatcga tcggccgaaa acgtctaagt gttggtgaag aagacgaggg cgcaccggga  55380 

atatatatac ccccggatct ttactcccgg ttgttgagaa caaccgggac taaagatatc  55440 

tttagtcccg gttgttgaga acaaccggga gtaaagaaaa gatatttact cccggttgtt  55500 

gagaacaacc gggactaaag atgatcttta gttccggttg gtattaccaa ccgggagtaa  55560 

atatcttttc ccgctatttc gaaattcttt ttaaacccgg ttagggttaa gaaccgggac  55620 

taaagattat agcactacat atgattttcg cttacatatg tgtttataaa atagaagtta  55680 

atgcattaac attatttaaa gtacaaagat taatgacaat tacttcgaaa aattattttt  55740 

gtctgtaata aattaagtgg ataaatcgta ataagcaaat atatgactta taattaataa  55800 

aaattccaat atatatatat atatacttag catatatatg aatgatatta ttatattggt  55860 

aaaaactcta attaagatat gtatgtacat actgcatgat ttaaaattaa taaaaattgt  55920 

aatcatcata tatacttagc gtaggaatta tattaaatta aatgctaaaa actctaatta  55980 

acatatgtaa atgccacatg catgatttaa accttttaaa aattcgaata gtcatatata  56040 

agtagcatat gaaagatagt aaattaaatt gtgaaaaact ctaatatatg aatgatagtt  56100 

ttaaaaatat attaaattta atacttttaa aaattctcca gtcaattata attagcatat  56160 

gaatgatagt aaattaaatg ttaaaaactc taattaacat atgaaattgc cacttgcgtg  56220 

atttaaaact tttaaaaatc ctctagtcaa ttataattag catatgaatg ctagtaaatt  56280 

aaatgttaaa aactctaatt aacatacata tgaaattgcc acctgtgtga tttaaaactt  56340 

ttaaaaattg taagtatcac atataactag catatacatg atttaaactt gttgaaacct  56400 

ctaataatcg tgcgtaatta acatatgcca tacatcaatt gatttatatg gataatcaat  56460 

acatccaaaa tagtttacat catgtacaca ataattacgg cattacatcg gcggtgacgg  56520 

ttgaccgcac gtactttctc ctcactattg ttccctcctt gtgatcgctg cgtgagtaag  56580 

gggtgtcttc atttgatagg aggatgctag ggtcaatcgt caccgtgaaa gggggttgcc  56640 

catccaactg atcgtaatcc tcgtcagtct tgtcctcaac tccgacgatt tttcttttgc  56700 

ctgggagaac cacttgacgc ttaggctcat caggccctct gcccttcttt cctttgctag  56760 

acatgtcctt cacgaaaaag acttgcgtta catcattggc aaggacaaaa ggttcgtcgg  56820 

agtatccaac cttgttaagg tcaacagttg tcatcccact gtcatcaatc attacgcctc  56880 

caccagtcaa cctaacccat tggcaccgga acagaggaac cttgagagga ccatagtcaa  56940 

gttcccatat gtcctcgatg gtaccataat acgtggcagt tgttccatcg tgtcccatgg  57000 

catcgacacg aacagcgctg ttttggttcg tgctcttcat gtcttgggct ctcgtgtaga  57060 

atgtgtaccc attgatctca tatccctgga atgtcgcgat cgacccagac ggtcccctcg  57120 

ccaggaaggc aagttgttgg ttgatcgact cgttacccat gagatgttgt cgtagccacg  57180 

cggggaaagt atcaatgtga tgccgtgtaa tccatgcatc ggacttaccg atgttcctgg  57240 

cgcgaactag agccaagtgc tcctcgatgt aaggagctac caatgaagag tgttgcagaa  57300 

cagtgaaatg ggctttacgg aataaattgt tgtctaccgt cattattgct ttccttccga  57360 

gagttccctt tccccgtagt ctcccttcat ggcgtgattc aggtaccccg attgggcgaa  57420 

ggtcttcgat aaattctacg caaaattcga tgacctcctc tgttccataa cccttggcga  57480 

tgcttgcctc tggacgagca cggttacgaa catacttctt cagaacgccc atgtacctct  57540 

cgaaaggaaa catgttgtgt aggtacatag gcccgagaat acggatctct ttcacaaggt  57600 

gacaaagcag atgcgtcatt atattgaaaa atgaaggtgg aaatatcaac tcaaaactga  57660 

cgagacattg caccacttca ttctgaaggg cttctaatct atccggatcg atgaccttct  57720 

gcgaaattgc gttcatgaat gcacatagct ttgttattgt tgcccggaca ttgtctggaa  57780 

ggatacccct tattacaact ggtagcagtt atgtcatcaa cacgtgacag tcatgagact  57840 

ttaggtttgt gaacttcttc tccttcgtgc ttattattcg cttgatattc gtggagtatc  57900 

cagacggtac ctttatgctc tccaagcatt caaacatact ttccttctct gccttgctaa  57960 

gagtgtagct ggctggactc aagtaatggc ttcctttctc ctttggttcc gggtgaaggt  58020 

cgccgcgttg ttccatatgc ttcagatcat tacgtgcttc cagtgtatct ttcgactttc  58080 

cgtatacacc taggaagcca agaaggttta cgcaaaggtt cttagtgagg tgcatcacgt  58140 

cgattgcgtg gcgtacgtcc aagaattccc aatatggtaa ctcccaaaat atagagttct  58200 

ttttccacat cgccgcgtga ccatcttcgc tctctatatg ctggcttcca ggcccctttc  58260 

cgaacactac tttaagatct ttaaccatag caaacactgt tttcccgctg cgatgtttag  58320 

gcttcgtacg gtagtcggcc ttatgtttga agtgcttgcc tttcttccgt accgggtggt  58380 

ttgctgcaag gaatcgacga tgacccatgt atacaacctt cctacagtgc ttaagatacg  58440 

tactttctgt ttcatccata cagtgagtgc aagccttgta ccccttgttg gactgtccgg  58500 

ataggttgct aagtgcaggc caatcgttga tggttacgaa cagcagcgct cgtaggttaa  58560 

actcctcctg tttgtcctcg tcccacacgg ggacaccttc cttcttccac aactgtttaa  58620 

gatcttctac cagtggtctt aggtacacgt cgatgtcgtt accaggttgc ttggggcctt  58680 

gaataataat cggcatcatt atgtacttcc tcttcatgca tagccagggg gggaggttgt  58740 

agatacacat cgtaacgggc caagtgctat ggccgctgct catctctcca aaaggattca  58800 

tgccatccgt actcaaacca aaccgtatgt ttcgtgcgtc ctttccaaat tctttaaatt  58860 

ttctgtcgat gtttcgccat tgcgaaccat cggcggggtg tctcagcatc ccgtcctgtt  58920 

gacgctcttc agcgtgccat cgcaacattc tagcattccc cttgttcctg aacaaacgcc  58980 

ttagccgtgg tattataggg aaataccaca tcaccttagc aggaattctc ttctttgtta  59040 

gctgcccgtc aacttctcct ggatcgtccc gtctaatctt gtatcgtagt gctttgcaaa  59100 

cagggcatgc ttctaggttc tcatactcct caccgcgata taggatacaa tcgttcggac  59160 

atgcgtgaat cttatgaact tccagtccta acgggcagac tatcttctta gcctcgtacg  59220 

ttgtctcggg caatttgttt ccccccggaa gaatgttctt gacgagtttc aataaatcgc  59280 

caaatgcctt gtcactaacc ctattttttg ccttccattg caacaactcc agagtggtat  59340 

ccaacttttt gtgcccctgc tcgcaacctg ggtacaacga agttctgtgg tcctccaaca  59400 

tcttgtccaa tttatgggcc tccttttcac tttcgcagtc ctccctggcg tcctgcaaca  59460 

tctgaccaag atcatccgca acgtcgttac catcagcagc tatttcctcc tcgcccgttt  59520 

gatttccttc aaatccaaca tactgagcaa agtccggaat attgtcgtct tccacttcat  59580 

cttcttccat ttcaacacct tgctctccgt gggatgtcca acaattatag cttggcatga  59640 

accccgactc aaacaagtgg aaatgaatag tcctggatgc agaatactcc ttctgattct  59700 

tacacttatt gcatggacaa caaataaaac ccctttgcct gttagcttcg gccactctca  59760 

aaaaatagtg cacgccgtca ataaactctt tggaccaccg gtcagcgtac atccattgcc  59820 

gatccatcta catgagtcaa aaaaactgta cacaaataat tattcttaca ataatgacag  59880 

tcatacaata attataagat atctttattc atacaaaaat cataaaatat tacaccaaat  59940 

aattcttaaa aactatttgt aaagttttaa actaatttta atgtgtttta cttcttttaa  60000 

ttttcatttt agtttgtttt ctattattta agattaactt tcactagagt tttccttctc  60060 

aattatttta taaaaccttg tttagcaaat gaactaaatt tctatatatt ctttcttccc  60120 

cacacacatt ttctctctca tcaacttaca actaaatttt ggagacaaaa aaagtgtgca  60180 

aaacataggt gcaaatgtag tatgacaaaa aaaacattgg aggatgaagt tgcaaacctt  60240 

ttaggcacct ccgatttgta tgtaatcacc aaaataaatt caatagaaat tttggcatga  60300 

cctcccctct tttttgaaga aattttgaag cttgctcggg cagctggagg aggaagaaga  60360 

catatatata gggatgggac tttagtcccg gttggtagca ccaaccgggg ctaaagatca  60420 

ccgggatctt tagtcccggt tggtattacc aaccgggact aaagttacga tctgttacca  60480 

accgggacta aagatcccgg gggggcctga caggccctga cagcattcaa accgggacta  60540 

aagatgatct ttagtcccag ttggtaacac aaaccgggac taaagatcaa atatgcccgt  60600 

tacccttttg aaccgggact aaagatcatc tttagccccg gtttttattg catccgggac  60660 

tattgtggaa atcggccgac cgacgaaaga tggtttctcc accagtgata tgtaagtaca  60720 

atgtaactaa tatatataat tatagtgcaa ttataatata attaatatgt acatacagta  60780 

taactaatac agtataagta agtattgttt tggtgaaaca attagttgct ccttcttgct  60840 

cagctagtta tttcacgttc aaagcatcag atcttgggat cgactcccac ggaggttaca  60900 

gtagtccttt tttttggttg taacggcagc tagcacaaat cataatgcaa tttagacggt  60960 

ggaaaatctg ggagatttct aaaaaaaaaa atttgtcgac aaatttttag caaaaccaaa  61020 

tttggataac tatataagaa atcctgctaa aattttagta agttgtcaaa attttgacaa  61080 

ctatatcaaa gttttggtaa tgccaaattt tggtaaggtc ttattttgca tcaaagtgaa  61140 

catgccctat gttattatta cttcagcatt catggattat aggttctata aaagccttgg  61200 

gccgtacgtc ttgtgatcga gttgtgcaaa tagatctctg agacaggcgt cgaacacctt  61260 

tttccaccat ggaatcgtgt gcacggcggt gcgccgtctc cggcctgatg gcgctgtcca  61320 

tgcgcctcac caagcagctc tccgccgccg ccgccgccag caaggctggc gctgccggca  61380 

acctcgtctt ctcgccgctg tccatctact ccgcgctctc cgtggtcacc gccggcgcgc  61440 

gcgggcgcac cctgacagag ctcctcggcg ccctcggcgc agagtcccgc gagaagctcg  61500 

ccgcgaacgc cggcgagatg gcgcgtgctc tccccgcccc cggcggcggc gcggcacagc  61560 

cgggcggcgg cccgcgcgtc gcgcacgcgt gcggagtctg gcacgagcgg acgcggacgg  61620 

ttaggccggc gttccgcgac gccgccgccg cgtcgttcaa cgccgcggcc ctcgccgtcg  61680 

acttcctcaa caacgtaagc gaactatata tatatacaca tgacaagatc taccaatcta  61740 

atctgtcatg tatgcgtgta gccggaggaa gcgaggaagg agatcaacag ctgggttgcg  61800 

gcggcgacgg agaacctcat cgacacgatc ctcccgccgg ggtcggtgag cacggacacg  61860 

ggcctcgtgg tcaccagcgc catctacttc aacggccaat ggcggactcc tttctgtaag  61920 

gagataaccg agaagcgggc gttccaccgc ctcgacggcg gcgacgtcga ggcggacttc  61980 

atgcgcagcg gcgaggacca gtacatcgcc gtgcacgacg ggttcaaggt gctcaagatg  62040 

ccgtacgcgg cttgtgtgag cgcgaggacg acgacgacgc cgaggtactc gatgtacgtc  62100 

ttcctccccg acgagcgcga cggcctgtgg agcctggagg acaggatggc ggccggcggc  62160 

gagggcttcc tccgcgagca cacgccggag cggcgcgtcg aggtcggcga gttcaggatc  62220 

cccaggttca agctctcctt cgacgacagc gtcgtgggcg ccctccagcg tctcggggtc  62280 

agggacgtgt tcaagccgtt cgtggcggac ctggccgacg tgctggaagc ggagaactct  62340 

ggcgatgatc cgccgctgtt tgtgtcggac gtcaagcaca aggccgtcat cgaggtgaac  62400 

gaggagggca ccgaggcggc cgccgccacc gcggtttgtc ttaccttcgc atcggcggcg  62460 

ccatcgtcac ggcggccggc gagggtggat ttcgtcgccg accatccgtt cgcgttcttg  62520 

gttttggagg agtcgtcggg tgcggtgctc ttcgccggcc acgttgttga cccgacagat  62580 

gagtaattcc atcttcacgt catgaaattt gttttagctg catttttgat tcggttatga  62640 

aatttgtgga cttccaatta agaacgattt gagttcctcg actccgagga gtggaattca  62700 

ggttgtaagg gtaggactaa gccatgtttc gtcttgttca ttggcataga gagacgcttc  62760 

tttcgtctca ttatattgac acaatgtcac aatacacagt gaagagcggc tccgatagga  62820 

ctaagctatg tagtagattt ttcttcgcaa tccatttggt cagaaaaaaa aaaagaacag  62880 

ggcgttttac tcatggaaac acaatgaaca tatgccacaa actataattg cacagaacaa  62940 

ttctcctttc ttgagatgcc acaaactagg atgagacgaa atttaggatg taggggtttg  63000 

tcttccgttt tgctgtcatg acgctacttg taaggacagc cttttggttt ctttctgctt  63060 

attttgttgc ttttagagct ggtagcaagt ttgggagtct ttcatgtttt ccttttggag  63120 

ggctttgaac ctccctatgc tataaactgg tgtctgggtg ttcccagcac aatcctctgg  63180 

ctttcaatag aagccgggcc gtacggcctt tctcttaaaa aaaataatgg taacatggag  63240 

aaggcgtgca taagaacaat taagaagaaa gctagttgtt gtgggaaccc taatcaatta  63300 

gaataattcc atcttctcct aataaaattc acacaaatgg tcgaacccta attgttgtgg  63360 

gaattacaga gagcaaaacg aagtttttac taagaaattg catggaggtg ccttcccatt  63420 

gatttagact tgatgcaaat taaatttgtt gaattccttt tgaatgatcg attcaagttc  63480 

tattttcctt tctcaaacac gcaagagagc gtcattatat tattaattga gattttctcc  63540 

cattcttgga ggggtatata cctaattaca atttgagagc cataacccaa caaccaaaca  63600 

aactttatga agaaaaacta atagagaaac tgcacccaac aaccaaacaa aatttatgaa  63660 

gaaaaactaa tagagaaact gcttgtttag tacaaacttt atgggaaaaa aaactaatag  63720 

agcaaatttc tgagaactac aagttcaatg actaaactat gaacttgctg caactttagc  63780 

aacttatttc agtttgcacg gtaacacctt taaaaaaaaa gtcctagcat tatagttgca  63840 

aaccaactat agataggact gaaaatcaaa ttccccttta agatatgcac gtagcgagga  63900 

ggtgttgcac attttcttcc tcttgatcag aaagctgcca ttaccccacg tgatcacgtc  63960 

tatggcgagc caaccgaaag gcaggccaac atctatcttt tttttttagg ccaatcaaac  64020 

aaagagaacg cactagtaca gaaaacgcta ttggtgccgg ttggtaactg gcaataggtg  64080 

ccggtttccc aatcggcacc aattggtcgg caccaataca tccttccggc acctataggt  64140 

aaaacagaac cggcacctat aggtccacac gagccaaaaa aaaaacctcg agccgatcca  64200 

gaaccgaaat atccccacat cccgaatcca gaagaacccc tccacattct gtaatcccct  64260 

ccatccacaa atccagaata atatccccac atccaaaatc aaaatccaaa gaacacatca  64320 

ataacaataa caattcctac attcatttaa ttataatttt catccaatcc aaatcttcat  64380 

gttcttggta cacacatgaa caagagaaga gaaattaaac aagagaagaa attaaaaact  64440 

cgaaccacgg cggcggtgac ggggcccttg gccgcctcct ccttcccctt aagcgtcgtc  64500 

gggatgctgg gaaggggagc accgccgccc acgggagggg agggcgcggc ggtgctgccg  64560 

cctccgtggg agcccgccgc ctcccctctc gccggatctg gcgaagggga gggcacggcc  64620 

gccgccggcg tagcgggagc tcgccgcctc cctactggct ctcatgtcgc cggatctgga  64680 

ggagggagcc caccacctcc cctcctgccg gatctagcgg aggggaggat gcggccggcg  64740 

ccgctgccac ctctgccaag cagtcaccga tcgcgcgagc ccgccgccac ccacaagtgg  64800 

tcgccacctc cgccaggcaa ccgccggccg cgggagcccg ccgcctccaa atcgagcgag  64860 

agagagaggg gaggtagacg cgagtgagag agagagggga gggagagaga gggatgcgag  64920 

agtagataag gacggtgggc tcggttagtc ggctaggctc ggtttttttc aaaggtgccg  64980 

gttctattaa aaaaccggca cctctactat atgtgtcggt ttttttaaga actgacacct  65040 

atacttatat tataggtgtc ggttctaaac aaaaaaccga cacctatagt atatgtgttg  65100 

gttttttaat agaaccgcta tagtgtttaa aggtgtcgat tctacttttt tttcatcgtg  65160 

tggaggtggg aaaagggtca taggtgtcgg ttttaaatga accgacacct ataaggccgg  65220 

tccctatgtg ggtttttgta gtagtgatga caacgtggtg gaacctatgt acaacaaatt  65280 

acctaccaag ggttatactc cctctgtccc aaaatatttg acgtcgttga ctttttaaaa  65340 

tatacttaac cgttcgtttt atttaaaaac ttttttgaaa tatgtaaaac tatatatata  65400 

tatacataaa agtatattga taaatcaaat gataggaaaa gaattaataa ttacttaatt  65460 

tttttgaata agacgaacga tcaaacatat ttaaaaaagt taacggcgtc aaatatttag  65520 

ggacggagga gtactcaaca gccctctacg aagtaacgaa gctatgacga ttttgttgag  65580 

aaaactttca atggggacga cgtctaaaaa tgctgatcct ctgttctagg ggtgatattg  65640 

cctccaagcg tgttgtataa ttagagatat tccagtaatg cctttgccct cgagtcgtcc  65700 

cttatatgat aaagcctcct atggtgattt ttggggcagt tcagaagttg tttcattgtt  65760 

ccctttcttg aattgtttca ttgccgacaa cgctgaattt ctcgggcggc tgcagcgtca  65820 

agcttactac aatggtgata tgtgcctatt tcatcacttt ggtggctcaa cgtcttccca  65880 

tagttgttca actcctcttt gtggatgttc aatgttcaat ttgtaaataa tgtttgacta  65940 

ggatgtcagt tgttcattga atcctcttgt atcttatcct aaggactcgt tagtttgctt  66000 

ttatttttat ttctagttcg attttggcgc acatcttctc ttcttccgca tgtcgcatgc  66060 

gcaaccaggg tttaccttac cgccccggta actacacggt taccgcggtt accaagctta  66120 

ctgcgatgta cggtaatata aataccatgg taacctcctt aaattcaaat aaatttaaaa  66180 

aataatttga atttttaata aattttgcac agtttttcac ggttaccacg tttaccgtgt  66240 

ggtaatcgtg cttacctcta ggacgcggta accctggccc cggcggtttg aggaaccctg  66300 

tcacaatgtg cgttggcgcg tggatacgat gaccgtacag cgcagcgtct ggcggccact  66360 

ttgcctggga gcacgagcca tcggatcgct cgtcgtcgtc tcacgacctc gcctggattc  66420 

ctgttcgtga ggggggcttc ttgcaaatat accaagatgc agacggttcc aaaaaataat  66480 

taaacagtaa cggctggtac caaggtaact gccatagtga aattagatgt ttggaaatga  66540 

taataactta ttaataatct attgtgcaaa aaaaagcatc tatcagaggc acacaacgat  66600 

aataatatat taatttatta cattacataa aaacatctat cagagacaca caacgataat  66660 

ataataactt attacagtgc agaaaaaaca tatatcagag acaacgataa tataactaga  66720 

tagatataaa agcagtcggg aaaccaggcg gcagtaaccc atcatggtgc agtgacctat  66780 

ttatgcctgg gataatacga gtagaaaatt atgcataagt cagtgattgt accaactgaa  66840 

atataagaga taatctgaga taacttgttt tctctttgct agttacacca ggaacaaaaa  66900 

tataatgcaa ggtaattaaa gtcatttatg actgaaatag aggcgtcact acaataatga  66960 

aacgacacta aacttcaact gggtctaatt gtggttgcca tgctcggcgt tctgaatgca  67020 

ttgtgcttta gggtggattg gtggctgacc cgattgtgtt gtgctctcgt atggcaaaca  67080 

caacacaaac ggcaaacttt tatttagtga aatatggcat ccccagcagt aaaacctaaa  67140 

tatgcataaa taaaatacag cataatcatt gcactatagg tgagactcac cccgaaacga  67200 

aattttttct tcaccctcca tgtgggcaac tccttacatg atatcttccc tttgttccta  67260 

cagcagagag gaaaggggga gggagggaga gtgagctttg caatagcaac ataaataaaa  67320 

tgttcaagtg aaagcagggt tttaaatctc ccgctaaact gccgctatct cccgctatag  67380 

ctgtttgaga aggattctag ttatttgttc tcatgtacaa tttagccgct atatatagct  67440 

ccatttagcc cgctatagct gctgctatag ctgtttgaga agctaaccgc taaatgcctt  67500 

agctagctat ttaaaacatt gagtgaaagg aacaatcgca gtttaccaga acaaacattg  67560 

aaaactgggc acctaccagt atgcaggaga gcaacaggtt atgatatggc acatgatgct  67620 

ataaggacct ggaatatctt tttcttctgc aattactcca tctgttgctt gtgataatgt  67680 

gccattactg aggtggtatt gactaagata gattttggtg tctggcatga caatggtgtc  67740 

aggaacaatg gtagggaacg ccttagagct gacacagagt gacctcctac caatgaagag  67800 

tgcattgcca tctatggatg tcacatggac agtccttccc agcataagat cagctagcct  67860 

gtaaactgag tagtaaaccg catcccattt tgtgccaatc accaaaatct cagagttgca  67920 

ttctaccaga cggtaggaat acaatcgaaa gctttcatcg cttgttggcc atctaaattt  67980 

tgcaatcaac tttggtgatg gctccgataa acagtgctgg ggtgggtcga tctgtatgac  68040 

ctcatgctca cctctcaccg aatgaggtcg cagcagcaca taaagcttcc catggaatgg  68100 

caatgtagaa gaacggtggt tgatgcgatc ccaggttgta gccaccctcc attgctgatc  68160 

accggaggta gcaaaacata tgttccacac gccgatcggc cgcatcatta ccctgacgag  68220 

tccatctcct acacccacgc tgatgcaggc gccacagatg tttcgaaggg agcaccaccg  68280 

agacgcctcg gagcggcagc gcacccgcgg caggagggta tccagcggcg ggagctccgc  68340 

ggtgtcgccg gtgaaggggt ggaggaggcg gatggctgtg tcgtggtccc tctgcagcag  68400 

gaggacgccg tcggcgtcgt agaggacgca gtggtccctg aaatggggca gcctgacgcg  68460 

gacgacggcg ccggtcgaca ggtggaagga gcggacgtgg ccgcggagct tgccgtggcc  68520 

cgggtggagg ccgcggccct cgggcagcag catccacccg cgcgggtgga agcgcgggtc  68580 

gaggatgccg cggcggcgcg ggcaggtggt ggcggagcgc cactggggac acacggcccg  68640 

gaagcggatg tagtcgcgga agtcgccggc tgccactcgc catccgatta ggctcaccaa  68700 

gtcctcgtgc agagacgccc acgacgagga tggatcgccg gcgttaacct tccgcctact  68760 

gctgcacgca actaaggcca tatgacatgc cgctgcaaca aatattagca gcacatctag  68820 

ttcaccaaac tatattcgcc caaggaacaa aaatagtaca atttttatta gggaatcacc  68880 

tgcaggcaaa ggaccagcgg cagatgcaaa ccttggcgtt cgcagagggc ggcgtatcag  68940 

atgggggagg aagccctagg gctaagccgc tgcgccctac aaggccgacg agcctaaggc  69000 

tcagaagccc attaacggga cagagagccc aaaacatacg gtctatagat agactcttgg  69060 

gactctaatc taaaccaccg ccgggccagc acgcacgtcc gcacggcctc ctgcgccggg  69120 

aggagggaga ggatgcggtg cagtattgcg tccgggagta gggatggcaa cggggtgggt  69180 

tgggctggaa cggccccgtc cccgacccct gacctctcca cccggcccgg cctcggcccc  69240 

tgccccgagt gaagatgcgg ggccaaacca tcccctgccc ccggcccctg cagggatccg  69300 

 
           
             7  
             11460  
             DNA  
             Oryza sativa  
           
            7 

tttattttag caagcttcaa aatgattttt ctcttaaatt acttatccaa tatatgaccc     60 

gattacacca ttgtattcgt tttaattaaa tctttacaac aagatatcgc atgactatat    120 

tttgataaag gaaaaacata tgctacttgt tgtttcatat gtgatagcaa tatgtttcaa    180 

cgtgtatctt caccatgttt cataaaatat ttaaatgttt tagttgctga ttttttttac    240 

cgtatataac ttaatgtttc acttattggt aaactgcaac atttgaccat ccgatttttt    300 

gataggcatc ggacgtccga tgggtagctt tctccagaca tatggggtcc acgtgggtcc    360 

ccctcatcat gtcagccaaa accgatcact gtattatcga gtgatcaaag ttaacgaggt    420 

attgtgagtt gtgtcagcca aaaccgatca ctgtactgtg gagtgatcaa agttaacaag    480 

gtattatgag ttgaggatgt gctataccgt atttcggttc aggggtgaat ggtagactcg    540 

gcgacaaatt gaggaaccta aagtgaactt ataccataat gaaatgaacc cgtcggccca    600 

gatcagatcg gagaccaatc ccctcgactc tgcggcggcg gagtaaacga gcccaagcaa    660 

gcgctcgccg gcggcggcca tggacgacga ccgtcggcgg cgcctcttcc tggattcttc    720 

aggtaacgcc cggattcagt tccctgcgat tttggtgggg ttgccccatt cgattcattc    780 

catgaagata ttcccaggtg tcgattttaa gggtttcgtg tcaattgcgc ggcagattcg    840 

tgttctagtg cgttcaatta tgttttctag gtgttcatcc ttcttgcatg tttaatctgg    900 

ttaaaatact ggcacatgaa atgcacagag ggttcacact tgcatagtac atctgtgcag    960 

caatgcatct gctcttgctt gcaatggcct acgatgggag ttgtcagaat ttcttcagct   1020 

aaacaatagt agtagattac aacaaagttc aaacgctgca tcatctgatt gctttagtta   1080 

ttttttctga aattcgagaa tgcaatctaa ctcataaaag tgaacccacc attagataat   1140 

aaacaaatgc tatgagatca ttctgcagaa caacgatctc aaaaatgaac agaaaggaaa   1200 

aacattgtct aaacgcagtt caatagtaaa agggcctctt acaacaatct ccaaagcaat   1260 

caaaataaca gaagaacact tcaggtccag atggataaga aagcgaatgt ttcaggtagt   1320 

gctagcaaag tagcaataac tccataacga tgaacttatt ggaatggtca atggacctga   1380 

caaatgcaga ggcatcaaac aagattgcta atgtagggag aaggtaacta gcactcctag   1440 

tcccctacac aatcagccat tttttggtcc atctcactct caatccagtg agcttcaaag   1500 

tcccagtgca gaccaaccag ccagagtttc ttcagggtcc gaagggtttc aatgccagga   1560 

gggacactct ccagccctga cagagcaaca atgtacaaac cttcaatgac tggaagtgca   1620 

ccacttataa tttttagctg gttgacatca ggcatgtgct tcagcacaag tgtcttcagg   1680 

catgggaaag ccgccgcgcc aagaaccaat ctgcaacatc tatatacgga cctctgcaac   1740 

atgcagcatc ttctggtgca tcccgtcacc tttccattga gtcttgaagt ctttgtgcag   1800 

gtccttcaac cagagcttct tcagggaggc aagggattca atgccttgag ggactttatc   1860 

cagcttccac aatgatacaa tgtataaacc ttcaatgcat ggaagggcgc catccgtgat   1920 

gtttatctgg ttgacatcag gcatgtgcat taacacaaga gtcttcaggt gggggaacgc   1980 

ctctgcatca agaaccaaag ttttcgaact gtgcacgttg ttcagtctta gataagtgag   2040 

gtttgacaag tgtgatgcga gcatccccag tggatcttcc ccaagattac accaacttag   2100 

agctaagtac ttgagatgtg tagtgtggct acgaaatatc gggtagtcca atgtgccctt   2160 

ggcccattgc cctctgataa ttaacctgtg gagttctttg gacatgggct ggagagcctc   2220 

aaagcaaaga ggttcattct catctcttgc agaaagaagc aagctagaaa gaagcggcat   2280 

agttgataat gtagcaaaaa tatttccaca atcagcagaa cttatgttgt caatccaaat   2340 

acttcttatc tgcattagtt ccttcagctg ctcggccaag tccttgctgg cttccacagt   2400 

ctcaagagtc tgaagttctt ccaacttaga cagatctttg ggtgcttgca ttccaatgaa   2460 

atagcgaaac actgactgct tctcgtcttc atatctatca gctagcaggt gccttagctt   2520 

cttgatctta gtgattccac gtggtagctt ctctattttg gtttgcttga tgtccagagt   2580 

ttgcaggttt gagagcttct caatagactc tggtagtgag cagagtcttg tccgccttaa   2640 

gccaatgtaa cgtaaattaa acaatttacc tatgcatgct ggtacttcag tgatatctga   2700 

atcttgtagc tctaggacag tgaggtattt ggattcagac aaaattgagg ataacaatcc   2760 

aggagggtgt gtagttgttt caagtagtgt gcgaagatgt ggaaatttca ctgttgatgc   2820 

acaacctttt ccattgttca agaataatga cagacgacgg acttcccaat caaccttttc   2880 

cacagctcca taatcattta cgcaaccgaa cctctcctgt ccagcaattg agagagccag   2940 

gttgcgcaca atgtcatgca tcttacaaga tctcaccctg ccaagctcat catactcgtc   3000 

aacttcaagc atgttccggt ggatcagttc catgagattt atttcggcca catcttctgg   3060 

tctattgtgt tcggttctca ccgcaaaacc ttctgcaacc cagtaccgca caaggctctc   3120 

acgagatatg cgaaaatctt cagggaacag gctgcagtac aagaagcagt tcttttggtc   3180 

agctggtaat gcatggtagc ttagtttcag aattgccttg acatcatcat ttttggccag   3240 

ctcactccga agctggttgt acatttgttg ccaggcatgc tcagtttgta gctttgtgga   3300 

catcaggaca cccatggtaa caagtgctag gggcagcccc ttacacttac ttactatgga   3360 

ggcagccaca ttctcaaggt ccagcgggca cctatggtcc tttctgttgt aaaatgccct   3420 

tctgcagaaa aggttgaatg catcaatttc acccaaagcc tgtatcttga gatggcattc   3480 

agagggagca agaactgcca catgttccat ccgtgtcgtg atgataatgc gacttgcttg   3540 

gggattctta agcttgccct gtatttcgaa gtacacgttc tggtcccaga catcatctag   3600 

cacaatcaaa catgatgtac tgttttcagt ccttctgttt aattcttctg tcaaatcttg   3660 

aacgcccatt ttgttgatta gatcttcctt agattctgat gattcttgtt ccatgcgtat   3720 

gagctcactg actagctgcc tacaaagact aaggatcgtc caagtctgtg acacagtgat   3780 

ccaggcatga actgggaact tgatcttttc acgttcatat acgtctaagg ccagggtggt   3840 

ttttcccagt ccacccatac cagacactgt tattactttg tgacctggtt cttcagagta   3900 

cagtaattca agcaaccttt tcctgttgta ttcaatcccc acaggatcgc cacattcaag   3960 

caacttcctt cttccttgag attgcggtgt ttcgatgtca gtgggagttc ttggaatgag   4020 

ctgaactgta ggtaaccatt ccgtttgctg tcttttaacc tgttcaatat caccctttat   4080 

cttcattacc tcactagcaa cttcactgaa aacacctgca taatgtactc ttacgaacct   4140 

catcactgat ccttcttgct gcagttgaca agcatagtat gagtacttgt ccattatgtc   4200 

ttcaacacgg taagccagct tccgcagctc gtcgatccaa ccctttacaa cattcatgtt   4260 

ggtatttgtg gaatctaaat cttgtattac atctttcatg acacgcaatt cccttctgat   4320 

atactcaact ttgtctggaa gttccctcaa gttagttacc ttcccagaca gtttggctat   4380 

gacagctctg gtggcttcat ctcccaatgc aatactgatc tttgagatgg caagcagcac   4440 

agcttctgcc attaccttag tgctgcagaa cagaatcatg aatcatggag atagtcacat   4500 

aacgaattga taagataaaa aaggttgttg ttacagttgt aaaacaattg cagctaagat   4560 

tgttttttgg gcccttgtgg gcatttgcaa gccatatata tatatatttc taatgttaat   4620 

catggtgtac caacagatat aggtaaagga gctcctcatt acgtaccagc ctcaacagta   4680 

atcttaattg taagggtaat gttctatggc aattgtttca taactctgca atgtgaccaa   4740 

ctgtgtaact taggtcctgt ttgggggagc ttgtcccagc tgtaactttt cccaaaagct   4800 

gcttctgcta gaagctaccc caaacagtcc acagcttctg agaatctgta gttacagaat   4860 

ctgaaaaatg aactaagaag ccagaagctg gagaagctgg gtttcagagc ttttccagat   4920 

tctcagaatc tagctaccaa acagttgctt ctcagaatct aaagctcccc caaataggcc   4980 

cttaatagga gatcaaagta actcataatc agatagtctc atagtttagt tgagtgtgtt   5040 

gtttcttgaa gtaggtctct attcaggttt ttaatggttc cacagataga ttgatcattt   5100 

agtataactc atatgtgccc agctttttaa tgcttcatac aaaggccagt atctaatatg   5160 

tgtgagtatt tcatgcacca tcacttcttc catgttctta aatgcaatga agtatatatg   5220 

aaacagccca gatatatctg aacataatat caaacatgat catagtttgt ttctaatctt   5280 

acttttcttt taagcagcca tttctaatga caactctgtt ttggattctg ctcttctagt   5340 

ctgttacacc atgcttagat gataggtttc ttgtcagtag aaacctactt gtgaattctg   5400 

gcattaagct gctgaaccta ctgataagta cttaaagaac atgactgtga ctcaatttct   5460 

ttttaagtga caaggagcag accagcaatg ctcttaatat gaagtagaga tgcacaccac   5520 

atattccagt gttctctttc tcagcatgga agtgctgaag cgcatgtggt tcgattcttt   5580 

tgcttataac aggtagaggt caacatttta catatccttt tacaaaacac accgtttagc   5640 

aatacggaaa acacattaac gaaaaagaaa aaagttgtcg ttttgagttg ctgaaaagaa   5700 

ctaccctcta actgtgaata taagagatta taacccttcg atttgtccac aaatacaagg   5760 

gatcgtggat cctgaggtga gcaaacaaca gaagggatgc agcaacattt taggccccct   5820 

ttgattcaaa ggaaattgat agaaatttta gaggatttca ttcctatagg aatttttctt   5880 

acaaagcctt ttgaattaaa ggaatgaatc ctatggaatc ctataaaatt cctatggaat   5940 

gcctcttccc atacaagttt tggaggaatt ttaacaagag gtagaacctc atgaaaaaat   6000 

cgttttgagt ctttatctct catcaaattc ctgtgttttt tctgtggtcc aatcaaatgg   6060 

tcattcatac gttattcctg tgttttgcaa tcctctttta cacttacatt cctgtcagaa   6120 

ttctatgttt ttcatattcc tccgtttttt tattcatgtg attcaaaggg gcccttagct   6180 

ttttcttact tttttttagt ttattcaatg tgccaatcgg cctaatccaa ttagtgcttc   6240 

cctttatctg tactttttcc tattccttaa tttctattaa aaaaaatata atccctcgta   6300 

ttacgaacgg agggagtacc gtttagcact ggtgtagatc tgttgtatag gcagggtcat   6360 

ggttgatttg ttatgagatg cacttgataa tgtagtgata aggggtgcgt ggtttcaatc   6420 

ccaaggtccc atgttcaatc ccaacacgct tacaatttat tcttataata aaaactagca   6480 

tggtggcccg cgcagactgc gcggctagca ctctactttt aattttatta tgtttattcc   6540 

aaattttagt tagttttaaa ttcctatatg gactctatac tcaacttcta atattcctta   6600 

tttttttatt tcgaatttct attttttttc ttcattgaat ttctatatgg actctatact   6660 

ctacttctaa tattccttat ttttaattcc gaatttcagt tatttcctaa tcgtatttct   6720 

atatggactg tatactctac ttctaatatt ccttattttg aattccgaat ttcagttatt   6780 

tcataattgt atttctatat ggactctata ctccactttt aatattcctt atttttaatt   6840 

ccgaatttca gttatttcct aattgtattt ctatatggac tatatactct acttttaata   6900 

ttccttattt ttaattccga atttcagtta tttatttcct aattgtattt ctatatatgg   6960 

actctagtct catcttctaa tattccttat tttttaattc tgaatttcaa ctatttctaa   7020 

atctctactt ttaattttat tatgtttatt ccaaatttta gttagtttta aattcctata   7080 

tggactctat actcaacttc taatattcct tattttttta tttcgaattt ctattttttt   7140 

tcttcattga atttctatat ggactctata ctctacttct aatattcctt atttttaatt   7200 

ccgaatttca gttatttcct aatcgtattt ctatatggac tgtatactct acttctaata   7260 

ttccttattt tgaattccga atttcagtta tttcataatt gtatttctat atggactcta   7320 

tactccactt ttaatattcc ttatttttaa ttccgaattt cagttatttc ctaattgtat   7380 

ttctatatgg actatatact ctacttttaa tattccttat ttttaattcc gaatttcagt   7440 

tatttatttc ctaattgtat ttctatatat ggactctagt ctcatcttct aatattcctt   7500 

attttttaat tctgaatttc aactatttct aaattgtatt tctatatgga ctctagtctc   7560 

ctcttctaag attccatatt ttttaattct gaatttcagc tatttctaaa ttgtatttct   7620 

atatggactc tgtcttttct ttttccctaa ttaatgtgag aatttataga ccatgagagc   7680 

aaacatagag gcttcttctt ctattccttt aataatataa tagatgtttg cccttcaaat   7740 

ctcgtttatc tggttgactt gttactgttt ctttatttgg tcctagttgt ttttgtcttc   7800 

cttttgtaat ccatattaat tctgtacagc cgctatagta gcactggatc ttttgtaaag   7860 

caacatttca actatatcgc aaattgattg gccattagaa aatttcgttg ggctactcat   7920 

ctttcatgct ttgttcttgg tgaaatgatt ggtaatagtt tccacgggca ttcaatttta   7980 

gcttaagatg tccttgcagt agatggccaa caataagata ataaatgata aaaatacggg   8040 

aaacatgtaa ttaacacaca gtatttaagg tgatgcactg caaacaacag taatcgctaa   8100 

atgttgcagt tgaatcagca ctgaacaaaa caacaacaca aaggttcttt ccccatctct   8160 

gaactgagaa tgtgctgctg gccttagata tgctcgctca gggtcaaatt tcagaacaaa   8220 

tttcccaata ttttctagca aagagactaa ttagtgatcc ctcctctcaa caaggcgaaa   8280 

ttcacgaaag aaaaaggcag aattttccag cagacataat cagaaaagtt aaagctgata   8340 

acagctacaa actagctaga tgatacaaag caagatccag tggaaatcaa tctaacctga   8400 

gctgcagacg atcagagcgt ctagaagagc agagctggcg agacgatcag agcatgtgag   8460 

gtttaagata ggcaacgaag aaaatataaa gcacaaagcc actagcctca aatctcaatc   8520 

agatccttgt ctgtttctct gaactagccg ccgacgactt gacgcgaagt cgacgcggct   8580 

aagcatttgc agtgccaatt atcaactggc caagttgtgc gtgtaggacg ggagtccgct   8640 

gtggaagctt cctttttcct gatctcaaaa tttatagtat accctccaaa ccgcatgcag   8700 

tgggggatgc tggattcttt ttaaatggac cagaaactcg agaaattatt gctcaataga   8760 

ttattttgcc tatagtaaaa aggaaaagaa aaagtaaatc agaattgttc atatcgaaag   8820 

gaatagaata tctgtagtcc agtatgcaaa ttagaaaaga tacagttttg attagtttac   8880 

tgtcctgcag ccagctcact ggtcaggctg ttcgctgcat cttggacata tactcccttt   8940 

gcccaaaata taagagattt tagacggatg agacattttt ttagtacaag gaatctggac   9000 

atgtactagt aagtgtcaca tctgtttaaa atcctttata tttaagtacg aatggagtag   9060 

gaagaaacat atcgttatat ttgaggacgg agggagtagg aagaaacata ccgtgtcacc   9120 

ttaacagtcc ttgtacttat gactcagttg ttgaggacct agttagctag tcggcaactg   9180 

caaaaatata attccagtct ccttattcta ctcgctaatg acagcttaga gaaagctaac   9240 

aaactgattt cttatgtttt catccaacta aaacggccgg agacctccaa gtcgtcttag   9300 

tataaaaatc tctcaagtca agtttcctcg atttcttggt cgtcgtcttc gtccaccttt   9360 

tggtatgctc gattttttta aaaaaattat gactcttttt gtaaaactta tttatgaata   9420 

aatagactcc aaaaatctaa ttatggatat ggactctact cggtgccggt gagcttggca   9480 

tcgaggtttc gtgcacccac gctggagacc ttggcatcga gttagagggg gagggggaga   9540 

gagtgtcgat gttgtagatc acgactacgg tatttgcaga gtttggggat cattcgtatc   9600 

agggtataag cgagactaag gtaaaataaa cggagacaag gattttcatg taggttcagg   9660 

ctccttatct accaggtaat agctctactc ctgctaattg aaaccagtgt tgctcttatt   9720 

catcagaatc acacaagtac aatatttggg ataacttatc taatcatcgt caacacggcg   9780 

gcatgaacca ccacacgttg tcgacaacag ggtagtcctc ctcctctaat atgaattggg   9840 

cgatatcaga gatagcgcta gatccctctt gtcagcctct gtggcaccag attggatctg   9900 

tttaggttta tctcttatgt tgatgtctgg cggcatgtat tgatgtatat tttgactgtt   9960 

gcctgtctat ttagactcgg cttgtcttgg tccgtctccc cctcttcttt taggggtctt  10020 

gtatttatac ccatagatgt ccccttatcc aaatagaact agaaagataa atatggatac  10080 

gatccgaata gtccttgtag tttccatgta gaactctgct tctccttcct tatctggaat  10140 

accttccgta tgcaagattt gattccgtat aagacttggt atatggtagg tcccgctaag  10200 

cttaacccaa cactattggg tatgccttac ccataaaact gatagggggt aggcgccatg  10260 

cttcttggtg cggacaccga gttgtcccga gatggcatgg gatggcatga gtgtacaacg  10320 

agcaccaaga gtctgagaca ccatggaatg gcacgtgttt ggcaactttt ttgacaagta  10380 

gacaagcacg atcgagacac ctaaacgcct tgcggtgatt gtagtatcgc caaccacctc  10440 

aatctagcaa aagctagacc aagatgggtt ttgataaact aaaccggcta gcggagccga  10500 

tttagataga acaatagata actacccgtc tcgtgggtaa acggaaggtt tacgggacaa  10560 

acctacaaag gatttcgcac tctcgtagtg aaggcagacg atttatggca caaatcgaca  10620 

aagatggatg aactagacta gaactagatt gaaatattga aaaagcaatt taattggcta  10680 

agttggattg tgtgtagatt gtatgctcaa ttgaaccggc cttgtccctt atataggggt  10740 

tgatcttgcc tcctacaggt cctcctccac gtccaactca ggatagaatt caaaggaaac  10800 

ccgaaatata gcctcctgag taaggaatcc tgagacctga cgaaaacaga ctcgggcttg  10860 

gactctgccg gtctgaccgg ccacatgccg ctggacagac cggccctcaa gtagcggtct  10920 

gaccgaccaa caaacgacgg tcagaccggc cctatggagg aaaccggcgg ttttcccaaa  10980 

tcttagcaat tttctttaat ttgaacagac aaacgacgat gatgagcatg gcgcacctca  11040 

accctccctc ttctccattt caatccctgc ctttttatca gttgattcta ccttattttt  11100 

cctctatgta gctcctaatg ttactacttt ctctatttca tattataaga ctttctagca  11160 

ttgctcgcat atatatatat atatatatat atatatatat atatatatat atatggcaac  11220 

atatcctatg cacacaggcc ctcacgtgta cacacggtgc acaccaacta aaaaatgtca  11280 

ccaataaatc tagaaaaaat catacacata ctttcaattg tattacacct agggttaaaa  11340 

tcttaacgtc aaattcatta tattttagcc gtaacaaaaa aacaaaaaat ctgacagttt  11400 

taaggttgca attttgtcag aattttatct tttttgttat tctctatgta gaatgaattt  11460 

 
           
             8  
             3159  
             DNA  
             Oryza sativa  
           
            8 

tgatatataa gttaaattgg agactagaaa tcgcaagcca cttgttgttc tcttttgtaa     60 

catgatggtg tgtgttcttt cagaacaaat ggctgaggca gtgctccttg ctgtcaaaaa    120 

ggttggcaac gtgttagcag atgaagctgc caaggctgtc attgccaagg tgtctgaaaa    180 

ggttactaat ctgaaggagc tgccagagaa ggtcgaagaa ataaggaagc aactgacaat    240 

catgaacagt gttatactac agataggcac ctcttacctc actgatatag ttgtaaagaa    300 

ttggattgca gaggtgagaa agttagccta ccatgttgag gacgtaatgg acaagtactc    360 

atatcatgct attcaacttg aggaagaagg tttcttgaag aagtacttcg ttaaaggttc    420 

tcattacgtc atggtattta gtgatattgc tgaggaggta gtcaagttag agaagcaaat    480 

ccagcaagtt ataaagctta aagagcagtg gttgcaccct tcccagctca atcccaacca    540 

gcttgctgag agtggcagac cacggtctca cgacaacttc ccatatcttg tcaaagatga    600 

agatcttgtg gggattgaag accacaagag attgctggct ggatggttgt actctgatga    660 

gtcagataga gcagtgataa cagtatctgg tataggtggg ttgggaaaaa ccacattagt    720 

cacaaatatt tatgagcgtg aaaaggtcaa ctttgctgct catgcatgga ttgttgtctc    780 

ccagacctac aatgtggagg ctctattaag aaagctcctt agaaagattg ggtctactga    840 

actgtcactt gatagcttga acaatatgga tgcacatgac ctgaaagaag aaattaagaa    900 

aaagattgaa gatagcaaat gtttgattgt gctggatgat gtctgggaca aaaaagtgta    960 

ctttcagatg caagaagcat tccagaatct tcaagcaact cgagtcatca tcacaactcg   1020 

agagaatgat gttgcagccc ttgctacctc agcacgccgt ctcaacctcc agcctttgaa   1080 

tggcgctgat gcatttgaac tcttctgtag aagggctttc tataacaagg gccacaaatg   1140 

ccccaaggag ctagagaagg ttgctaattc tatagtggat aggtgtcatg gcctaccact   1200 

agcaattgta acggtaggaa gccttctgtc ttcaagacca gcagcagaat ttgtttggaa   1260 

taaaatatac aaagagcttc ggactgagct agcaaacaat gatcatgtcc gagcaattct   1320 

aaatttgagc taccatgacc tatcaggaga cctcagaaat tgtttcttgt actgtagctt   1380 

gttccctgaa gactacacaa tgacacggga gagccttgtg aggttgtggg ttgcagaagg   1440 

ctttgtgcta agcaaagaaa agaacacgct agaggatgtc gcagagggaa accttatgga   1500 

actgatccac cggaatatgc tggaagttgt ggacaatgat gagattggca gggtaaactc   1560 

ctgtaagatg catgacattg tgcgtgtatt ggctctttct attgctaaag aggagaggtt   1620 

tggttcagca aatgatcttg gcacaatgtt gcttatggat aaggaagttc gtcgcttgtc   1680 

aacatgtgga tggagtgatg atactgtatc aacagttaaa ttcatgcgcc ttcggaccct   1740 

gatctcactt tcgacaacct cattgtccct tgagatgtta tcctcaattt tgtgtggatc   1800 

tagctacctt acagttcttg agctgcaaga ctcagagatt actgaagtgc cgacttctat   1860 

tgggaatatg tttaatttac gctacattgg tttacgacgc accaaagtca aatcacttcc   1920 

ggagtctatt ggaaagttat ctaacctcca cacgcttgac atcaagcaaa ccaaaattga   1980 

gaagctacca cgaagtgttg ttaagataaa gaagctaaga caccttttag ccgatagata   2040 

cgttgatgag aagcagtcag atttccggta ctttgttgga atgcatgctc ctaaagaact   2100 

ttccaacttg caagagctgc agactctaga aactgtggag tctagcaaag acctggccga   2160 

gcagctgaag aaattgatgc aactaagaag tgtgtggatt gacaacataa gttctgctga   2220 

ttgtgcaaat attttcgctt cattgtcaag catgccattt ctttccagct tgcttctttc   2280 

tgcaaaagat gagaatgagg aactctgctt cgaggctctc aggccaaggt caacagaact   2340 

ccacagactg atcatcagag ggcaatgggc taagggtaca cttgattgcc caatatttca   2400 

cgggaacggc acaaatctta aatatctagc tctaagttgg tgtcatcttg gcgaagatcc   2460 

actagggatg ctcgcttcaa atttgccgaa cctcacttat ttgagactga acaacatgca   2520 

tagtgcaaac attttggttc tttcaacaga gtctttcccc cacctgaaga cacttgtctt   2580 

aaagcacatg cccaatgtga accagcttaa gatcatggat ggggcgcttc catccattga   2640 

aggtttgtac gttgtgtcac tctcaaagct ggatatagtc cctgagggca ttgagtccct   2700 

tcggaccctg aagaagctct ggcttctgta cctgcacagg gacttcaaaa ctcaatggca   2760 

caagaacgga atgcatcaca agatgcagca tgttccagag attcgtgttt agatgcggct   2820 

gacaggtgcc gtttgtagta gttttttttt tcctcgtctg tttgcagctc aggtgttgat   2880 

ttccaatgag ttagcttttt tgcattcgcg gtgcgtctgt acattttgta tagtttcatt   2940 

tactttgata tttatctatc tatctatcta tatctattat atactaaaag tccattaaac   3000 

ttcctataaa cactcctaag ccgctatgtg gcatcctata aacgctctcg agacgccaca   3060 

tgtcactcta acaaaataga aaaatttgac catcgatttt catttaaatt ggtggaccta   3120 

ttaattttga ccgttagatt tatttttaca ttaaaataa                          3159 

 
           
             9  
             12024  
             DNA  
             Oryza sativa  
           
            9 

tttatttttt tgaaaaaaaa tatatcaata atttatttaa gaaaaacatc tcgcccacct     60 

tatccctatg tggtgtgcat cgttcatcct tttctcttat ttttattctt ataataattg    120 

aaattaaaat tatctttatg ggaaaaaacc acaaatggac ctccacataa caggtctagc    180 

tagctctccc atgatccctt ttcttctctt tctcatctta ctaacattta tgggaacaat    240 

ataaataaaa taatataatc ttttaaatca tatattcaac ttatgatttg tttgaactat    300 

tgtattttct tagtgaaatc aactttaaga tccatattga gtatatttaa atgctaacat    360 

aaaaattaca ttccggaccc acatccatct tgaggcatcc acttagtaaa aaaatgaaaa    420 

ttcatcatta taaatcaaaa tatcacatct taatttttaa taaagcctgt agacctatta    480 

cctgtatcca attagacacg taacaacttt ctatcaactt aattaatttc tctcaacatg    540 

tatatggggg taatttgcct atacaatttg actttggtgc tttttatcaa taaatgatat    600 

ttttaggaga taaaattata tataatctat gaagtcacta ataaattaga ggaaaaaaat    660 

ctttaaatga taacaatttt atgtcataat gtgtactcca tctagcgtta attttttata    720 

gacaacattt taaaagtaaa aaacatgctc agttgaacat ccaactgata gtaccaaaca    780 

tgtggattgc accgagaaat cttttttttt tgaggaaatg caccaagaaa tcttagcagt    840 

gaaacaactc tgaggtggca ttaccaatat agtgaatata gtgagttaat tccatatgga    900 

attaaagacc atgttcattt atttcttttt ggtaaaactt gctatgctac atcgtaaatt    960 

cataatattt actgtagaat aatatagaaa tgtgcattta ttatatgacc tctattttca   1020 

tattcttact caattccaga gagataatta gaatagatga ttttacccca tgtcaggttg   1080 

taggcttaac ccacatatat ttataaccca aattgcagat atcaaatcat ttcaaagatg   1140 

cttggtagaa tggaattctc caatttatta aaaatggaca tgaaaagaat tcaaaattta   1200 

tgtaaatgtt ttaaaaaatt gttgggttta aaacccgttc taaatggaaa tattcaaata   1260 

ttttagcagg actaatagaa cgaaaatatc taaaatttcg aatagaatct gataaaaatt   1320 

tggacttttt gagcaaatgt ttggggaaag atatccccat gggtagttga aatacccaaa   1380 

attttttcat aggaactaca tctattgtct cgacataata ttatctcata aattaaaaac   1440 

tgtacgattt taagtaattt tagtttagaa tttatgtgct acaagggtaa ttagaagaaa   1500 

atcataacca acgttgaaag cacattaaat aagttaaata ataatttata tatagtaaag   1560 

taatatttta atacaaagtc acatatatag atattcgtaa taaaatttca cacatattaa   1620 

attaggtgca cgcgcatgtg cgcgggctac ctttctagtt attattatta ttatatacta   1680 

aaagtccatt aaactctcta taaacactct caagctgcca tgtggctacc tcaaaacgct   1740 

ctcatgttgc cacgtggcac tctaataaga aacagaaatc tgaccattaa ttttcattta   1800 

aatcggtggg cccattattt tacatcgtta gatctatatt agaaaaccaa aacgtccaca   1860 

actatggtcc cacatctcct tccgtgtagg taaggtacgt acatgagcgt acgtacgtac   1920 

aagaccgaag aaagacatcc gttttttctt tttcccctct ctttttctct ttctcagaaa   1980 

tactcgtaca aatgcgtaca tttgtcttat ttctggctag ctactttgta aaggtgagca   2040 

aggttaatgc aaatataaat acactgtgat catgtgatag gtaattatat atagattcac   2100 

gtagattatg tgagactaaa ttagctatgt aatatttaat atttaaaaat aaagtttaca   2160 

ccattatata tttacccaat aaataaataa tgtaagatag tttcctaaaa gtccattaaa   2220 

ctccctataa acattctcaa gctgccatgt ggctccctca aaacgctctc atattgccac   2280 

gtggcactct aataaaatag ataaatcatt attttacatc gttagaccta tcttaaaaac   2340 

caaaacctct caccggcccc acatccgtgc agtacgcacg tactgctcgc ctgttccgtt   2400 

ctcctttttt tttccctttg ttcctttctt ttgttttttc aatcacaatt aaaattgaac   2460 

ttatctttat agaaagaata cccccacaaa tgttaaagtc cattaaatat catataaatg   2520 

tttctaatcg ttgcgtggca cttttaaatt agagaaacat cgaatcattg gtttccacta   2580 

aaatcgatgg acacattatt ttacatcatt atttgatatg tattaactaa aagtccatga   2640 

aactttctac aaatagtcct aaatcgccac gtggcatcat agaagtgttc ctaagccacc   2700 

acatgccact ctaacaaata accgttgatt ttcattatat ttgatggacc tattgtttac   2760 

aacattaaat ttttcttaaa taaaaagtta accacccaaa cctaatccac ccatcctgta   2820 

aatagtaagt acgtacttat atctcatata caactaccta ttatatatga aaataataat   2880 

aatatacctc atatattatt attattatta ttattattat tattattatt attattatta   2940 

ttattattat tattattatg tygaccgtaa catatatgtc acrgtgtctg ccattctctc   3000 

tactttctat tttatagcta gcaattcaag gtaaacatga tgagctaatt tgtcatgatt   3060 

taatttataa ttaaacaaat taatttaaga tcaataaaat ctaaaagttc taagtaaaat   3120 

gcaaaacatc atattatcga tttacactta aaccgagaaa aatattattt tgatgattag   3180 

attagattta ttaaactaat taatccctca ctgctgatct cctccgtaat ttatgattaa   3240 

aaaattcaaa aagttgtgag taacaggcaa aatatggcac catcgattta cacttatcct   3300 

attattttta accattatag atctattaaa ctacttaatc cctctgtcct aatctcctag   3360 

gtaattacat aattataata attgattcat attacaccac cctcttccta gattaacact   3420 

tcattcttat gtttttatac tttattaggt acaaagagat atcttcgatt atatattaaa   3480 

agtccattaa acttcgtaca aacgctccta aattaccatg tggcattcta caaaacgcta   3540 

ctaaaccgtt acgtggcgtt ctaataaacc ggtggaccca ctatttgttt aataaatcga   3600 

taggcccact atttgtttaa taaatcgata gacccactat tttcaactat tatatttatc   3660 

tttataaaaa aacattcatc ataggaactc ataatttcct atgaggaatt atccatagct   3720 

atgaccaatc gatgtttgcc atcaaataat aaattgatta tcaatttttc tacaaaagtg   3780 

ggtagagcca ttaattatat atggttgtat atgtaatgtc ttttataact taagttttcc   3840 

ctcttttcct atggaatctc aagagcatat gtcttaggta ccatttttta taccgtaagt   3900 

taccaaccat aatctccaat aggtaatttt ataaataata attaaattcg tcatgcaatt   3960 

ctaacaaaga aaattcatta aaaaacacaa ttttaaaact ttgcagatat tatttcgttg   4020 

gtataccgcc tttataagtt tctcaaattt atcctacgta tgagacatgc ccgcgcgaat   4080 

gcgcgggcta ccttcctagt tgtatgaaag agcaaatcca ttttttttat aagacctcat   4140 

ttgcatgtat tgttgccaat atattaatct ctgtgcttgg agatatatgc agtggaaatg   4200 

agatgaaaca agatagtagg acaaatgcta tcaatgttat tatgcatcaa cgcaagcata   4260 

taataggatt taagcttctg gtcattcatg tatacagtct agatttttgc ctgctcagga   4320 

ggcagcctga gcgagtgctt gtttggttgc agttgtatgc ctgaggataa cagtacatat   4380 

cattctttga taattacctc aataaacaat atcaagagac ttcattaacg tgaaaaacaa   4440 

atagaaatat actcctgcgt tttgtctata tggttctaca tcgaaacttg aaaataaaca   4500 

agagtaaata aatgatgtag ggcagagtcc ggcgttggat tttgtaggcc tgagccaggc   4560 

caggccggcc acccatgaaa cgatccagga catcaaccaa acaagtacta cgagacaggc   4620 

gccagggaaa cgacaggtca ggcgaaaaca cttcagttca ggactccaac caaacagtcc   4680 

cccacatgcc tagttgatgt cacatgccaa cgtcagtgcc tatgataaca tgacgaccaa   4740 

ctgcctagtt tagtactaac taataactct gagcatgtgt tgattgtgaa gataacttgg   4800 

tggaatgcag aattgtacct ttggaaggaa taaatcgata ccagttgggt aaataaaaga   4860 

agttcctgtc aagccaccca ataattcaat tatgaagaca caagactccc atcgattttg   4920 

accttcagct tgcttcctag cgttctgcac tggtcatcta gctcttttct gcaaccatag   4980 

atatccagtt cttccagcga aggtgggaga cccttttctg gcagcttcct gatgccatag   5040 

caacacaaga tgtccaacct cttgagggag tgaaggctgt gcagacctgc aggaagatct   5100 

tgaagagagt agcaatgcgt aaagcggagc tcttgcaggg tcgtgaggag ctggagcgct   5160 

ctctcttgct catccgttag tctccactct tcgcttctga aaccgtaaat ctttaggtat   5220 

tcaagggaag tgaggtgctt gcagaatgac gtggtaagga tagaggtatc atcgatgcac   5280 

aacttttcta gtcgcagatg gccttgccat gacaaattat ccaaacatgg aggcaatctg   5340 

gggcattcgt gtacttgcaa actcctgagg ccatagagga attgcaagcc ctccagtacg   5400 

gcgagtgttt tacaatattt aatcgtcaac tcttcgagtg ccgtgcatga ttgcagctct   5460 

agagatatca aaaattcaga gtggtgcacc tctaattttt ttaggcaggt gagattcatt   5520 

tgaaagcggg ggcacagggt ttcaataaaa cagttgttga tgcaaagttc ctcaagtgat   5580 

tgtggaagga ggtaacccat gtgagctcta aggcccttta cctgcagcag ccttaggttg   5640 

ccgagcgatt gcaagccttc cagagaatta agcgattgca agccttccag agaattacta   5700 

gtaatttgta agcgcgcaca acgaattgtc agctcttgga gtgctgtgca ggaatgtaac   5760 

tgcagagatg tcaaacttac ctctctcatt agaaacagtt ttttcaggcg ggtgaggttc   5820 

cctggaaagc agagttgaag catttcaaag ggaccatcat attgtacaat aagttcttca   5880 

agggatatag ggaggagcca tcttctattc gcctgctcaa catttccatc attatgcaat   5940 

aaggaatcga tgagcttggg gcataccgaa atctctagct gctcaaggga ggtaaatcca   6000 

gccaaaccat ccttgctccc atgaaatgtt aaatcagagc accatttgat atatatcttc   6060 

ttcagagagc atatgatatt taacggaagg cgtggaagtt tgttttcagc ggaaaatccc   6120 

aatgatggag tctccgtagc tgacataaga tttggttgac cacattcttc ctctcctata   6180 

gatagacctg ttatctgctc gcagtcttgt aacctcaact cttgtagggt cttcatgtgt   6240 

tgtagcaaca gagatagcca cttccctgtt attccacaat ttctaatatc gagaagttta   6300 

agacatagga gggtgttgtg atctgcagct gccatgtctt cacgggtatc tgatgggaca   6360 

tttggagcga aaagttctag gcagttggat atttccaaac tcttcaaaga cctgagttgt   6420 

cttaaactgt ccaatgatat agtcgtaaga ttttgacaac cacatattac caatccactt   6480 

aagaacctca agttacggaa cgccataact ttgtcatcca acgttatcat ctgatcagaa   6540 

gattcatccc attcatccat ccaatcatat gaaaatccga ttcttaatgt tccactagat   6600 

gacccctcga ttgatggaag tgttgaaact cgggtgatgg ataatttctc gacattaggt   6660 

gaaggcggaa gaggtttgtg cacacgcaaa tgagggcaac catagatggt aatctccctt   6720 

agacaggaaa accatgacga ctgctcaatc tcaaattgcg ggtagttctc aaacaatgga   6780 

aagacctcca gtgcagggca actcttaatc ttcaaaacct ttaaattgtc attcaagttc   6840 

ctgatggaag tgcaggagca tgccttcaag cttatcaatt cagttaatac aagctcctcc   6900 

actgatggaa ttgagacttc tgttgcattc ctcattttga tcaacacaag ctttctaagt   6960 

aacgttagcc tttctaaagg aagtctttgc catttttcac atttttctag gtgaagtgtt   7020 

tgcagacagg taagtgaaga cggaaaccaa gttggggagg tagctccatt atacccagat   7080 

atccgtagat gcttgagact gtgatgtggt tcaagaccat caagcacctc acgtgctatg   7140 

cctggcaaat tttttaaaac tggggatata tttgtatcag ccatcgtcag tccctccatc   7200 

agaggttcta tgtcactgtc agtttcattt tcagaactca tgtctgtgtc atactcattt   7260 

tcagagctca tgccactgtc atatccatcc tttgcatcct tcgaggacaa atgtagcttt   7320 

tctaaattat gtttgtctct tagtcttgca ccacaagctt cgattctagt cgtaatagtt   7380 

tcaagtccag acacaccgag ctgtacaagt tggttcaagg actgtagttg gttcaagccc   7440 

aaagaattat gaacactaaa gtcatttaat tcctgaagag aggtcatttt gccaatgcta   7500 

gtgatggacg agaacacttg ctttgctgct acaagatgcc tcaggctaac gaggttatcc   7560 

atatcattag gtataataag atcagattct gaaccagcat caaatacttg gagatgataa   7620 

aacttgccga cagatagagg caaagctccg tcatcaaact ttatatagcg aatatgggta   7680 

ggattcacca gattcaataa cgaggggtca atatcagtaa atggtgcaga gatttgcaag   7740 

acacgtagat gatgttcctt ctggactata tctttgaagg atttgaggaa tatatggtta   7800 

tgctgcccaa ttagcaccaa agttctcaaa tgtttcactg gtttaactgc atttctaatt   7860 

ctttcttcaa ccttgccaca atcaggatct tcttggtgtg tagaatcggt taatattgac   7920 

aagtgacgta tagttggcaa cattttattg cactgtggat tatctatagt tgcgtactct   7980 

gttctcgaaa ccatccttgc aaaatcatga ataagcccac acataacata ggatgtcttg   8040 

tcaacttgag tgaactgatt tgtctgtgca cctggctgaa agaagccgga gtttaccaaa   8100 

ttagaaaggt actccctccc gatctcttcc agtctcttac ttgaagagtt acgatgcaca   8160 

aaaccttgag aaatccaaat atggatcaac tcctgtccaa ggaagcaata accactaggg   8220 

aatattgaac aatacaagaa acattgttgt aaatagtaag gcagctgatc atagctaagc   8280 

ttcaaagaag gcatgattcc tctacttata ttcagggatt tccaatcttc attcctcaga   8340 

gtgttgctcc agtgatcaat tgtaagatgc tttcttaata tttgccctgc tgtttctgct   8400 

gccaatgggt taccatttaa cttgtcagct attttctgcc caatgatgtt tagacttgga   8460 

tgtgctttat aattttcgtc atcaaatgcg catgctttaa aaaataacca aaagtcctca   8520 

tttgacaaag aatctaactt aatcggttcg actgtcccca cccgttgtgc aagagacaaa   8580 

attctagttg tcacaagtat catattgcct tttgcacgat ttgatttcaa tggagctaat   8640 

agaatgttcc atgtgttatc atccatgcta ttccatacgt catccaaaac aagcaggaat   8700 

tttttcgtgc ggatgtccat atgccttttc aagatctcct gaagtttggc aaaactactt   8760 

attgcattgt gtctttcttt tctttgatga gatacttcat gtctttcttg agagacaaaa   8820 

tctagaatct ccatcgtgag catcactcca tcgtagtctt tagataccca aacccatacc   8880 

tgatcaaagt tatgtttcac cattggatca ttgtatacaa gttgagcaag agctgtcttc   8940 

ccaactcctg caatgcctac aatgggcact acagttagtc catcgtaact gtcatctgta   9000 

ataatcttca ggatggcatt cttctccgcg tctcttccat aaattttgtg tgggctaaga   9060 

cttgacgttc ggatcagggt cgttgttgta cttgtacgat gatttgagtt tccaacaagg   9120 

tccgctccat gtagcgtgag aacctcacta acagccctga tggcaacttg taacccacca   9180 

gttatttgct gtatcctgct agaaaattca gccttattcc aagggcgtga atcgactgca   9240 

ttgttgttcc aagggtgtga atcgactgca ttgttgtgtg ttgactcatc aatattcctc   9300 

atcctttttc tgccggaatt aatcttcatc ctttttctgc tgccggaacc accgagttga   9360 

tcagtaatgg tgatatttgc tgtggtgtca gaagtactgc aaaattaaaa aggaaaaaaa   9420 

aaagaaggat cacacaatcg ctgctgacgt gatgaaccat gcaagtatgt tacattagtt   9480 

aaaaatagtg ccgggtaaaa acaagaagaa gaaaagaaca taaatcctac ctcgataggt   9540 

ttgggtagct tgctcgacgc ttgttcttac aactgatgct atggaggtga ttacgcaaaa   9600 

ccgacgtccc tgtgtgagaa ccacactcga gcacagtgtt acgaacacat cttgccttca   9660 

aaggctttcc attttccaat tcagtgatac gtaagttctc ccatgccccg gaccggcctg   9720 

ttttgccacc actgctactc gaaatatcag tggtactttt cggtgtcact gcctctgctt   9780 

gcagtggtgc atgtttatcc gcgctttcag gagcgccttg ccatgcatct gaaccaagag   9840 

aaagcggaat gaatgcacct ccctgggcag aaactaaaac ggatacatct tacatatcct   9900 

atcttactat aaagttataa cccactaact cctaaagctt aacatgcaaa gatgccacat   9960 

catcattcac taacaagttg acacatcatc atctattaac aatcaataca tttaatatca  10020 

tacaaacatg ctatattatc tataatttaa aatttattac attttagagc ttttaaaata  10080 

aaggcatgtt aaattattat cacacataat tcacataata tttcaatata tatcttcatt  10140 

atttattata atatcttatg cacctatgta agttcatcct cacttggtta atattatttt  10200 

tctcttctct aattaaacta ttattttggc tgtgtacacc ctcgcaaggt gtagaggccg  10260 

ggtttaatat aatccattat ctaaaaaaaa ttaagctatt atcacatcaa ttgattttag  10320 

tacttatgta agtttatgtt gttaagctat cttacacatt atttttactt attattatta  10380 

tattgaagtc ccgcagcaac acgcggggtt tcatctagtt acgtttatat tacctccttg  10440 

gacctggtgc tggagcctgt agtagtcgag gtcgtcgact actgcattgt tgtgcgttga  10500 

ctcaccaata atcctcgtcc tttttctgct gccggaacca cagagttcaa cagtaagagc  10560 

gatattagtt cagcacttac ttttttaact atttttaaag aaaaagaaaa gaagagaaca  10620 

taaatcctac ctcgattggt ctttacgctt atccgtacaa cggttgctac ggaggtgaat  10680 

atgcaaagcc gacgccccat tttgacactt gagctcagtg ttacagaaac tacatttgac  10740 

cttcacagcc tttccatttt catattcagt ggcaacaaag tacttccata ccttggacca  10800 

tcttttgcca ccaggcccac cactgcttct cgaaatatca gtggtaaatt ttggtctcac  10860 

tacctgatct gcttgcactg gtgcatgttt atgcgcgctt tcaggagcgc cttgttgcca  10920 

tgcatttgaa ccaacagacg aaagaggtga tgtacatctt acatgcgtac ggacgcttat  10980 

attacctcct tggacctggt gctggagcct gtagtagtcg agctcatcga cggcattgtc  11040 

ggcgtcgtag agcagctccc tgagacgacc gagcgatcgg gtcagcttgt tcccgattgc  11100 

tctctgccta acggcagcga ccaccacttt caccctctcc atctctgact taagcttctc  11160 

ggtggcatca gagagcccaa cctgacgaat ccactcgtcc agcttgtcgc tttccaggtt  11220 

ctccaggatg gtctgcgcca gccactcgat cccgccctcc agcaaagtga cttccacctc  11280 

tgccatcagg ttcggcggaa aactgctagc agttgctggg caattggcaa tggcatgaaa  11340 

tgatggttgt aatgattaag gtgctgaaat aatggttgaa gtgatatata attgggatga  11400 

ttaagggact attatttttt gattaaggga accggattat cacagacaag cttcctaaac  11460 

tcaagttttt tttttaaaaa acaaatcttc aataaatttt tttaattaga atatttttta  11520 

agaacaattt ttcaaatttg taacaattaa ttcattcatt tctgtcctcg aataaattgt  11580 

aatgtcatgg tgaaggttat gttgtgatga acaatttgca aatatgttca gacaagttga  11640 

atttcatgta tatgacttct tcgtagtttt tgtacattac atgttacata taatactcta  11700 

ttgttgcact aatttaaatc aagttggcaa gaacttgtgc tcggaatatg gtttagatat  11760 

tattctcatg tgcatgcatt ggttgaggcc gcagaagcgt ggttggtgac tggatcggga  11820 

ctaaacacag agggttaagg tccatatagt caaggatgtc atatgggatg ctcaggctag  11880 

agaactacat gggaggtgtg cgtatatgga taaagaagtt aaacttggag gaagtccaaa  11940 

tttggaggga tctgaatcct aatttggaaa gatagaaaag agttggaata tgacggagtc  12000 

ctagtcctag ttagattagg aact                                         12024 

 
           
             10  
             18155  
             DNA  
             Oryza sativa  
             
               misc_feature  
               (3312)..(3312)  
               N is any nucleotide  
             
           
            10 

cggtctggcc agtcccgcta ggcggctccc tcggagcagt gggtttgccc atcactactt     60 

aggtgccctg gaccaaacgc ggattcacca tctcgctaga acaagcccga ggggggggat    120 

ggggtcaaag cggcatctcg atcacggact gattatcccc ttttcccctg ttttttttgt    180 

tgttctctct gtttcaaaga cattcagtgg aaggagcaat gaatagaaga aacgaaaggg    240 

gaaaaggagc taaggaagtt tcaattgcaa aacaaggcag gatggcacga cggcctaaat    300 

acaagaggtg cccgctacgg gcgcacaaca agagggaatt gaaggcgcgg atagtcacgg    360 

ggtgcccggc cctccgaggc cggcgccgct gacaatgtcg tcccagtctt cgtcgctatc    420 

gtcgcccccg ctcccgcttt cttcgtccga ggccagcccg gaggtgaagc ggggggccga    480 

tccctcgaag cccgagacaa tcgcgtcggc tgcctcccga acttgctccc gggccctcgc    540 

ttcagttccc agggaaaaat cttcaagtgc gcgccacggc atgaagtcgg ggtcgcgcgc    600 

ttggtggctt gcgagaacca gctccaccgc ggcccgtgcc aaagaagctg acgaggactt    660 

tatggtctcg ccgacctcct cttccagtct ctccaggccc gccgctagcc cgtccaaccg    720 

gaacgcgagc gctggttgtg tgggcggaag ttggctatgc tggcgcacgg gaacgccgac    780 

tcggcgcgcc gcgcgctcca gccgagcgac ggcgtcggag agctgcccgg gcccgagttc    840 

gttggtgagg cggagggccg caatctccct agcctgatct tgcaccaggc gccccaggtc    900 

ggcaagggta ctctgagcct tggcgagcga gctcgccaac cccgcgccgc cgggcggccc    960 

gccggctgcc aggtgcttct cccgggcctc cagttcagaa gccctcgccg ttatcgccgc   1020 

gcgctcggcg cgagcgctct ccagatgccg ggcctcgcgc ctagcagcag cctcctcgcg   1080 

cttcgcaagc tgcttgccaa gccggcgcaa ggctacctcg cggcggttta cctcggcttc   1140 

gcgctcggcg agtgcggcgt cccgttcctg gcacacctcc tcccgcagcc gtagctcttc   1200 

cgcgcggcgg cccgcggaag cttccgcggc aagagtgatc cgatcatgct cagccgcggc   1260 

ctcttcacga aggtgaaggg aggcctccgt ttccgccgcc gttctctcgt gggtggccaa   1320 

ggtggactcc cgctgatcca gcaggcgtgc ttgctccccc agctcctggg cccgctgtgc   1380 

ctgttcctgg ccgcgcgcgt tttgttcgcg ctggctccga tcaaggacct caatccgccg   1440 

acggatcgtg gcttcaaact cctgcacgga gcgggcacga tcgtccaagg ccttgcgttc   1500 

agcctcgagt gccgcagtcc gggcctgcaa cgaggcgtcg gcctccgctg ctcgccgctc   1560 

gtgggcagcg gctgcgtcga gggtgccaca gcgcattcct gaccctctcc gctaggtcct   1620 

cggcatgggc ctcgtactga aggcggatat cgcccagcgc ttcgtccagg gcgctcgagg   1680 

cgatcagcgc cgcctgccgc tcctcctccg tctcccgcat gacggagtcc agcacctcct   1740 

cgcgcgccta gattttggct aggtgggctt agtgtttttt gcgccccacc ctcaccatgt   1800 

cctccacggc acggcgcccc tcgtcgactc gcgcgcggtc cgccacaagc tgagcccatt   1860 

cggcatccag ggtcgtccgc tcttccgcca gggcttgaac ttgggtattg agcccctccc   1920 

ggacagtgga gtcggcggcg gcgagcacct gcagaagtgg ctccatgctc gccggggatg   1980 

gggaagaaaa gcccacgggt cacccccggg acgacggagt gctgctggac cccccacgag   2040 

acgggggctg ctctcggccc cccttctgcg aggccagccc cgagggcgcc ccaaacgcaa   2100 

gggggagcgg ctgttctttt cgtcccccgc ttccagtcct cgggtggatt cggcctcggc   2160 

ctcgggctca gggccgccct gtcacatccc aaaaatccta aatttataaa ttgttgttta   2220 

attggaattt ttagaaatta aattaaaagc ctacaagcta aaccttaatt ttctaggaaa   2280 

attttcaaca taaaaatgag ctaaataaaa ttttattaaa tactatgctt gctcctctat   2340 

tttctagatt tttctgggaa ttatttgagc aagggaagta tttttaataa ttgaaacaac   2400 

attttacaaa ttgttttatt caaaaaagtt caaaaagtcc ccttcttggt ccttgggccg   2460 

aatccggccc atctctcctc tcttctctct ctttccccgc gctcggccca gctcggccca   2520 

agccgcgccc gcgcccgcgc gcccctctca cccggaggct gacaggtggg gctcacctgt   2580 

caggtcgtct tcaacctccc gccgccgccg cgcccgcgcc gaaccctagc cgtttttccc   2640 

gcatcgattc cggccaaatc cgatgcgatc tcttcaaatt gattgagggg ttttgttcct   2700 

ctcggtctcc tcttcctttt cccccaagaa tcaaagcaaa tggttgagtt ttggatgaga   2760 

tttggattcg gtttcgagtt tatctccaaa aataagtccg aattcttccc gattcgattc   2820 

catccgtttg cggttcgatc tcttcgattt gagctcatat aaatgttccc cgtgatctcc   2880 

tctctcgttt gccccctttc ctgagtcctc ccgtgcctcc tagcgccgtc gccgcgtgct   2940 

tttagccgtc gccgtcgccg gccgtccttc ggcattgccg cgccgccgtc tccgtcgtcg   3000 

ccgccggtcg ccgccaccgc cattagcttc gccgtgagga ggagaaggcc gtccgcccct   3060 

ccgtttgcgt cgccgaccac cggagcaccc ccgacgccgt cgacccgagc cgccgccgcc   3120 

ttcttcttcv tcgccggccg ccgtcgttca tcgtctcgtg tcggggtggg taccgttgag   3180 

ttcctctcgt cgccctctac gcgttggtgc cctccaatct cgtcgccgag gtccgtagcg   3240 

ccggcgagct cgtcgtyccg agccggccgy cgtcgctgac gtcaggctga cgtcaaccct   3300 

agggcagacg tnacctmtgc cagggctgac gtcatccttt tcctttttcc ctttttctcg   3360 

atttttaaat agattaaaac tttgaaaaat cataactaaa taaccgtaga tccgttttag   3420 

gtggttcaag tttctaaatt cttctaaaat caagatctac atgttaaaaa tatcccatgt   3480 

actgtttatg cttgtttttg tactgttttg ttgattttgt ttatttgctt tagtttccga   3540 

cgttccggag gagagcgttt ccgttgagga aggttccgaa gcgtttgtgg aagcccaagg   3600 

caagtcacac agatcccaaa caaccctttg agcatgttga tcctgtttaa agctattatt   3660 

ttatttcaac ttatgcatta ttttcgaatg tcatcgggtg gtgaaccttt cccagttaat   3720 

tatggccgaa gttgacttta ttttcctatg ggttataatt tgattagcat gaaccttata   3780 

tattggattg gttcagctaa atgctatata tctaggtttg cttagccatg cttagaaaca   3840 

ttagctaact aaaagggtta atggtaaact acttcattat tttatgttaa taattgtggt   3900 

tattttaatg gtagctcacg atggtcaatt gtgtgataat aattaattga taactaaaac   3960 

ctggctaagg tgggttgtga gcatatggtt ttgatggttg tgctcatgac aattaaggac   4020 

cggttcgcga gctactgttg tgatacattt atcgtgccaa ccacaagcca gcgtgggcaa   4080 

cggctttatc ttttgtatag catagttcat taaagtgcgc cagactgaga agtggcgaga   4140 

agtccatggg ggtcgctggg gagtccatgc ctctggttgt agagggggtg attatgatcc   4200 

aggtacggtg cactgtggtg aattgtgtta tgtgagggat aatgtcacaa ttcctttccg   4260 

agataccgtg gtggtattga ggcacatggt aacatgatgt ggggttgtgt cttgtgggta   4320 

cagtggtaca cctctgatca gagtttaatc tattcgaata gccgtacccg cggttatggg   4380 

tgagttgagc aatgtttttc gtgattagtc tcacactact cattaatggt aataatgtga   4440 

taattaattt aattcctggt ttggaatggt taattcctgg tttggagggt taatttgttc   4500 

agccggggtt ggttgatcaa atgtggttgg gcctatgcaa cacgggtgtg ttgtatggtg   4560 

ttgatttaat attgattaat tatataactg ttttattatt ctcttaaata tttattaaat   4620 

gctgttttct gcaaatgagc tatattatgc catcctttgt tatcctgtgc acttgcatat   4680 

ttgctgtgtg gcttgttgag tatgtcatat gctcattctt gcaatattca ttcatcagag   4740 

gaggagtact tcagtgaagg tgatgatctt gagaattgag cttattctgg ttaagttgcc   4800 

tgtggagtgg agttgccgtc gctgttccgt cgtttgtttt agttttatct ttccgctgcg   4860 

tagaatgttt tattttcttt gagaggaact atctacctct gtaatatttt aatttgcgag   4920 

tatttaatag ttaattattt gtactctatt atcaatattg tcattgtgtg cctcggttga   4980 

ttcctggacg agggcttaac acacatgtaa gcgtttggaa ttttggatag aaattccggg   5040 

cgtgacacgc ccccagcctc gacctcaacc tcgggctcac gaccgtccgc accaaccgat   5100 

cctgggtggc gctccgcatg gaccccagtc tcggagccgc ccccgggagg ggcgtcgacg   5160 

ccaccgccgc ccacggtagg tcgagtcccg gctaagggtc gctcgggatc gggcccagta   5220 

cgtgtcctgt ggaccccacc gcgaggttgc gaagaccctg tggtcttgga ttggccaggc   5280 

ccggaccgct ccggttgtgc ggatttcgtc ctccgtgagg ggtccgaccc cgaggtcccc   5340 

tgagaaggaa tatcgctaca agggaaccca gatcgcgtta acaaaagaaa aataaagggg   5400 

agggaacaag aggccgagct aggtaagagc accgaagtga gcgccagcgt ttgtacctgc   5460 

ggggaggaca gttgaaggtc cactttgggg gctcgatgaa gctccctcgg cacggctccg   5520 

tttgccctat cttccggagc cgtttcttct tccgaccggc ctcgggcccg gcaggtcgct   5580 

tgtgacccgc cggtggaagg tctgtcgcgc gctcggcgcc tcctccacgc gggggagatg   5640 

gcggccaaag attcggtcgc cttccgcttc cccttcgggt cacttgccgg gtcgtctctg   5700 

ggtttgcggc ccgagccggg cgcccgtgag tcgctaccac cgcctggacc gcttggccgc   5760 

ctcccgccca cggacgcgcc gccaccaccg gcgctggcgg cgctaccgct ggcgccccca   5820 

cggccaggcc ggcccctgcc ggcgccgacg accgacatca cggccaagat gctctcccgg   5880 

tcgcggtcgc agcagagggg gaggatcccw tccgggatca gtgtttgctc ggcggagtcc   5940 

agcccagcac ccgccgaatc accatcttgg cgtcctcctc gccccagtcc cagcgctggc   6000 

ccgcatgcgt gcgcatgggg tcgttggggc cggtatactc ccacgcgcca cgggatcgtt   6060 

cctggagagg ggcgatacgg cggtgaaagt agtcgccgaa gaccattgcc cctgtgaggc   6120 

ccaagcttcg caggcccctg agacgatccc acaccgcgtc atattcctcg cccagctccg   6180 

aagccgccag ccatgcggcg gatctctcgg gaggaccggc gggaactcga agtcgtgggt   6240 

gatccggcag ctgcagtgta gaaccagtct ttcttccagt cctccctttt cttgcggagg   6300 

tggctctcga tgtactgccc cgccgtgcct ggtcggggct ggaagtaaca tccgcccacc   6360 

accgcaccct atagcagctg cgggacgaag aaggcctgga acaaccgcat cgtcggtcgc   6420 

accctgatga acatctcgca caggtgcgca aagatgctca gtgtcatcac ggcgttgggc   6480 

gcgagatgca aggcatggat ttcgtagaaa tcaagaacct cgtggaaaaa tcgggagaaa   6540 

ggcggaatca atcctgccat ggcgaaggac aagaggtgca cggaccgctc cggatatcgc   6600 

ggccgtggcc gtgactcccc cgccctcacg acggcgccgt ccggcataat tttgcggggg   6660 

aggctaagat gtctgtctgc cgagatgcgg gaagaaggga gcactgtgtc gccggtgtct   6720 

tgagccatga tggccggcgg ggcagtgaca gaaggcgtgg cgcgcaaagc tgcgtggagt   6780 

ggtgagagtg ttagggttcg agaggcgaga ggacgagtcg gcggttagcg aaaggaagga   6840 

ggggaggtcc ctgcctccac tcccttttaa ttctcgcctc atccgcgctc gcctcctcgt   6900 

ttcccgccct cataattgcc cccatgtccg cagttgtctt tccatttccc gcgcccgttc   6960 

accacgtcgc ccgtcgtatc cgcgtcccac ctttagtgcg cctatcaccg gcgcactcga   7020 

ggtggaatgc gtaacggcta taagcgcaag ctgagtgaac cgtcaccaca accgccgtag   7080 

gaatagcggg cgaggtaatc gaggcgtggt ctaaccgatc ccctgattat cgcgtcccaa   7140 

gcatcctcgt ctttagcgcg atcagaggcg accgaaccgc cgctatggct ggcccgctaa   7200 

tctggccgct cggcaatact cctttaaact ccccgccggg cccataaccc cagctaggga   7260 

ggtcgtgagg caccatgtca gaccgatccc aggaagcccg cgtctgacat ggcgccgggg   7320 

gctactgtcg gagatatggg cccgggggta tgtggagtaa aggagagcta attccctttc   7380 

cagccacgtg gctctgcgag ctggtcccac ccacatacct cgtgagtcac taaggcgatg   7440 

gggagagcct cgggggtcga cgacatcccc tcgggggtga cgtcaccccc ctcgggctct   7500 

cccgtcgttt tagcccgagg ccctccctcg gggggaagtg tgagagggga gtccaggctg   7560 

ggcggccata aatgtgcagc gccccaaccg tcccttgctg cattcaatgc ggcgagggca   7620 

gacgtgcggc gtgcccgacc gacccctgtc agtcggatgc gaccggtctg tgaccagtct   7680 

attgccggtc acggccgatt gaacgggtgg tcgtgccccc acgtcgcctc tgtctccgcg   7740 

gagtggcggt aggtacgccc cgtcacatcc ggacgtcgtt cgatgcaggg ctgccgcaag   7800 

tcctcactca tttatgaggg aatgacaggg ctaccccccg tgtcagccgg gagacggtgc   7860 

tgggccccac tcaaggacca accgatgctt agcttccagc aaaaggcacg ggttgaaacc   7920 

cggtggcagg agcgagcagg gccccctccc ctccctccga tggaggggga gggtagagac   7980 

ggcgcatgtg gtatcccctt aagctataaa aggaggacct tgcccacaaa aagggggggc   8040 

ttttggaggg gaaagcaagg ggaaccttgt aagagttcac tgataatccc aaacacagga   8100 

gtagggtatt acgctccaga gtggcctgaa cctgggtaat cgaattgtgt gctatctaac   8160 

cggggatcgg agggacgaac acgcgacttc ggagagacga gtctctgccc tcggccgaac   8220 

tcacgaaagg ggggtcacgc gactccccgc gatcgggggt cttccctcga caacaatcat   8280 

aaaagtaaaa tgtccagtca aaaaaatcat aaaagtaaaa tgaatataac tatgagtaat   8340 

attcctaaat atattagtta gaaaacaaaa gtaatgctat aaagtaagca actataacat   8400 

ctaaattata tgactactat tgttctgttt gtgactattt tatatttaaa gagccatatt   8460 

cactatattt aacttttgat atgtcacttt gaggttatat tttctgactt ttgcgtgaca   8520 

ttcaaacaat tatgaaatta tgaaaaagaa ttatatagat tttatcgttg tatataattg   8580 

cacaataatt aaattagatc tatcatggta taagtaaaat gataaaagga ctaacttgga   8640 

ctatttgaat aaaatctaat aagcttgtaa aagaattagt tcttactctt tccttaaatt   8700 

ggaccgacca ttgcatgtta cgttttacaa ttttgagaaa attccttcta tacccctgaa   8760 

agtttagcca atcccttcta cgcccccgag ttttgtccac tcccttgtat gcccctgaat   8820 

tttggttttg atccctttcg tacccattcc gttagtttac cgttggttga atgtttaatt   8880 

ccaatgaaaa ggaccttttt gcccttagac aggaagggaa tctgaaagtt gtagactagt   8940 

tgtattgtcg gaagtgtata attttgttat ataagactat tatattcatg gctttattgt   9000 

acaaggtatt attcatggca aagtttattt ttacataatg acataaaaat aatatttatt   9060 

tacttattaa aagagcatat gtagcaattt tttggtagtt caacatattt tctcgagtaa   9120 

atttcacaaa actacaggta ttttgactaa attatcacaa aactacacat ttaaggagtt   9180 

gtatcacaaa actacacatt tagcaccaaa tttatcacaa aactgcagat tttaggttaa   9240 

gtatcacaaa aatgcatatt taatattaaa cttatcacaa aactacaact tttggctata   9300 

aacattatta atttatgatt aaattggttc taaacctgta gttttatgat aatttagtta   9360 

ctaaacatgt agttccgtga cacttcatct taaatgtgta gttttgtgat aaatttggtg   9420 

ttaaatgtgt agttttgtga tacactgagt taaatatgta gttttgtgat aatttagtca   9480 

tagtatctgt agttttgtga aatttactct attttctcct gttgtatata ttatattgga   9540 

atgctttcca aaactagatt tatctttaaa aaatgctaca catactttat taatatatat   9600 

taattttttt gtacgacaaa gttatgaata tgataatcac acaacaaatt ttatacttcc   9660 

aacaatatag tttacagatt tctacatatt cctcacatat tgaagggtaa aactgacttt   9720 

tttataccta ttaaacggtc aattaatggc aagggtacgg aagggatcca aatcaaaatt   9780 

cagaggtata caagggagtg cagaaaattt aggggcacat aagggattgg ctaaaattca   9840 

aggatatgga aggaattttc tcagttttta aatgcttaga tattaatggc cttatatcta   9900 

ttctgtatca tagaattatg agtttcttcg catattattg catatataag gtagttaaaa   9960 

tgttatattt gttactatta aatttaaatt tttggactta tgttaattag gtattttctt  10020 

ttaaatatat atatatatat atatatatca cgcatatcac gaggaagcga ggtctacgac  10080 

atatctttgt tatgtaagta tgcaacagct tgcgtcaatc tgaaccaatt aaaaggatga  10140 

ctaacttgat gctacaaata aaacatattt gttaatgata acagttcttt agaatgtgtt  10200 

aaaaaatcca ctaaacattc aattaaataa gacaaaacac cttacttgct tttcagttag  10260 

acaagtttta taaacagact agatctaact ctatactgaa gaaatcatat ataactattt  10320 

atagggatgt cttaaatatt acatgtttca aaagcaaaca aatagtttaa aaaaaaatta  10380 

cctaagcgaa gaaaatttat ggagaaatac tgcttttgaa acatgacagg tgtcatccgg  10440 

ttgatattcc atctatataa gtttttaaac gcaatctaca atacatgccc gcgcgaatac  10500 

gtgggctacc ttcctagttt tgtttttctt tttttgataa tctaccttcc tagttattat  10560 

taaaacatga taaagaaata atcctccaag ttcgtttcgt gacctagcta gaaagctatc  10620 

atattaataa gaaagcaaat aaatatttgg tttcattttg taacagtact cagactgatc  10680 

ccacacaaat tagagtacta caggaggtac gattatattt ggaataaaac aaatatatcc  10740 

atgtgtaaat tgcaatgaaa ttgtagatag ttctacgtaa aacaagtaga agttctagca  10800 

ttcgatataa tgtggtcgga gttggagatg caatagacat acctaacttg cggtcttggg  10860 

aagactttgg aggatcggtt gcttggaatg tcctgtgtac aaaccaacgt agaccataaa  10920 

gaaatgaatg tacgagacga gaaagagagg tagatacata taagagtgat tttacggttg  10980 

gaccttgagt acacctgaag atatatatga gattttgcat tataaaattt agatacctcc  11040 

tggtacatga agtactaaga gggagcaaaa attttacgtt ataaaatggt actttgaggt  11100 

tcatctttga aaatcataaa atttctccat aagtttcagt ttgcacatga aacacaatta  11160 

aaatttaatt tattattata ggtatagtcg gagaataaga aaactacaag gcttataagg  11220 

tccaggaagt gtgtcagata acatgtttgt tgtaattgag aaatgctttt gttgtgtggt  11280 

ggactgatgg gtgtaaactt ttttccctac ctcggtgttt aaatcgaata aaggtattgg  11340 

ggcttccaaa acacaaaaac cagttattgt gatttgcttc caggaacctc atgttttagg  11400 

gcaaaatgtt tcaaaaagcc ccatatttat gtaaaatcct cgtatttcat ttttacatat  11460 

gattatttgt acacaaattc atgttaactc aaagtacaca ttccgcttgt ctcatttatc  11520 

ttctcccccc cccccaaatc ttttattata tactaaaatt ccattaaact tcctacaaat  11580 

gctcttaagc cgccacgtgg caatcctaca aactctccta gatcgccaca tggcactata  11640 

taatctcacc gttgattttc acttaaattg gtggtcccga tattttagac cattagattg  11700 

catctgttat taaaaaataa taccttcctt tcacaggaga aatatataac tgttgcctaa  11760 

aagataaata ccttcctcac gtacgtacga ctaaaagaaa aaaaaaagct aaaccattaa  11820 

ttgtttgctg caagaaaaag aaaaagaaga ccacgtgcat gtacttataa gatagagaaa  11880 

aataaagaaa aaaaagaacg tagtaccgtt ccaaagaaaa atcgacgtta tttcatacaa  11940 

tttacaaatt tacgcaaata tacgtagctc tttaaacatt ccatctttta aattatttta  12000 

aatttatatc caatttgtga tactattgta ttcctttact taaaaagatg tctatgatcc  12060 

aaaatacatc atagcaccag cacatgggac ccacatgtat ataattgatg ttatgttatc  12120 

tatctattat ccatctatta tctatctatc tattatataa taaaagtcca ttaaacttac  12180 

tacaaacgct actaagccgc cacatagcaa ccctacaaat gctcctaagt ctctacgtgg  12240 

cgctataatt atttctaaaa aaatcaaaag aaggcaaaac atctgatttt tttaatctat  12300 

tcccgatgga cccattgttg tcaaccatta gatctatttt taaaaacgat caattaaatt  12360 

tatctccatc aatcccacgg acacgtgcat atatacaagc acagcacgta cgtatctaag  12420 

taaccagctg gcctcatgtc cctctttttc ttttcttttt ctttctaaaa taaaaataaa  12480 

taaatacacc gttagaaacc attagatcta tcatgaaaac ctaacagtta attttatcgc  12540 

taaaaatcac taaatacacg tgcacataag caccgtatgt aagtacgtag acacgttggc  12600 

ctcacaaccc tctatgtctg tttttttttt cattctgaaa tccaaaaaaa ataaaataaa  12660 

acaaagctac atttagggtt taaaagtaaa aataaatcaa gctataagct tccgattata  12720 

ggatagaaaa aacagtatgc aatttgaatt ccttattgat tcatcattgt attatccttt  12780 

ggtttccaca aatatgtcgt agcaattctg aaggaaaaaa aatcattttc tacctatacc  12840 

atgcaagaaa cacacaaaaa aatttaagtc cattaaacat catgcagaat gctcctaaac  12900 

cgctacatgg aactttaata aattagaaaa aatcatataa aaattataag aaaaaagaaa  12960 

aatacttagc tatccgttct aacttaaatc ggtggaccca ttatttctaa ccattaaatc  13020 

aatccttcaa aacacaaatc ccttccacct cccactccct cccgtacata atcactcctc  13080 

cctctccaac atccatatgt acaaagcata tatcttatat acaactcaat tagattaaaa  13140 

gtaaaaaaaa tgacacataa gttgtttcgt actcccccgt cccattttaa gtgcaaccat  13200 

aaaatttcat gcccaatgtt gatcgttcat cttatttgga ttttttttat aattagtatt  13260 

tttattatta tgagacaata agacatgaat agttacttta tatgtaactt aagtttttaa  13320 

ttttttttaa gttttttaaa agacggacgg ttaaagttga tcacggaaaa tcatggctat  13380 

acttagaaat gggagtagta agtagatttt taaggaataa gtttacatta atcactgtct  13440 

ttcttataaa taatggaggt acagtttcaa ccttttaata taaatgaatg gttacgatgc  13500 

tcaaatgtgc tttattgcgc actcatatca aaatagacaa attatcagtt tgaagtatat  13560 

attttttata tctttataac taagaaaata cttagaacat gtgacgagtt ataatgcacg  13620 

cataatgtta tgatgccgga ctcagtcatc atatagaata taattatttt aatattttac  13680 

tgcctaatta aatatgtcaa tgattgttag aataactaac gctcaacatt taattttgaa  13740 

aatatcaaac actcatattc aaaagaaaaa gatatagtag tataattttg aacgatatta  13800 

acaaagtgcc catagagtga gctataaatt ataatcttgg tggtttataa atctatacaa  13860 

tctagaaagt atcataacta cttaaaaaca tttttaggac aaatatcata tatttaaact  13920 

attatcaaat aacatcttaa gtaaaagtcg tcgtatatcc ctacggcaat aaaataaaac  13980 

caagatgtcc atgcatgttt tattccttca catagcatgt aggcaatcaa gctgctaatg  14040 

gaaagtttgt ttggttatga tttatgcatt gatagatgat attttgatct aggtgggtta  14100 

ataaattttc aattcccatg attttctaca ctccattaaa acatccgttc ttttcaatac  14160 

tctattttac acatgtattc ctatcatatt tttgtacatt ttctattctt tttttttcaa  14220 

tcatgtgtta caaaggaacc tttaattttt tttcaccgag aggcaaaatc ataacatttc  14280 

acaatcctaa taacacaaat tatgatggtt taaataagat gcccgcgcag atgcgtgggc  14340 

taccttccta gtttttcact aaaaaaaata aataatccta actaatattg atataataat  14400 

ttgttaaata tacgtataaa tgatcaaact actacgatcg caaaatgttg aaaatcatct  14460 

atgtacttaa aaacgtctca tatatatttt ttacaattgt tatagataaa tatattagtt  14520 

aaattgatga tataaatttt taggtgaggt ttaatgaaat attttgcccc caaacttgag  14580 

gttttatgaa acaaattata aaatctaggg atttgcatca tggattcctc aaaacctgaa  14640 

gttatgtgaa atttgctcca acataaattt cgtgaggttt gaggatgttt atcctttgac  14700 

tagtatttta aggataaact ctcatgtgtt tgtgggtgac ataaacgctt gttatatact  14760 

tattatacta tcggcaagta taaacaaccc atacctgcta tcgtcaaggt tacgctcatc  14820 

ctctggttcc atctttagag ttcggtgttg tttggttaac caatcatacg gagaacacct  14880 

ttctcccgga cacgctttca cagagtgcat ctccctttta aagcattcat atggtaaaca  14940 

attattattg tgaaaaatcc ctaaataaga tggtaaagaa atatcataaa aaaactaaat  15000 

aggatggctt cctatttatg agaacaatcc acacctgcta tcggaaaggt tccttgtatc  15060 

ttctagttct ctctttgttg tttggcgtat gtctatctct attcggtatc gtttgcttga  15120 

agaaccatct tcgtcagagc tctgtttttg tctgtccaga tgattagctt cctgaacctg  15180 

actgactttt ccaagaactt tgaaggtagg accgtacgga tgcttgccaa tggcattctt  15240 

gcaaacagat tcggcagctc cccggtcaga ttcgatagca ccagtggcaa ttccaattct  15300 

tgcactgata tccgtaaggt ttaataggtg ctccacgccc aaaagcgcaa taccatatcc  15360 

ctcacctcta tgggcatcga aaactagata cagcctctga agattgggca ttgccccttc  15420 

ctgaaactct attcgcagtt tatgacacct gaattcaaag aatatcagag cagaaaatgt  15480 

accttttttg aacacgatgc cttttgcagt gggttcctgg acatacagtg agagagctgc  15540 

aagggtaccc aattctgtca ggatatccat gtcgctatcc aggaattccc tgatcacaat  15600 

tttcaaaata cggagttctc gaaaatgagc aatccactcg ggaatttctg aaaagatgca  15660 

ctcagatggc aacagctcca gtgtttgaac gggaggagag gatgcgctcg ttgaatcatg  15720 

gaggctagca gtcgtgtgtg aggtactagg atccatactg tgattcttga tgccatcagt  15780 

aactcctggt tgatttggca taccttggaa ctggagtggt aagaaactga gatgaagaac  15840 

attcgatgga acaactgcgt cgtttgcatt tatttccagt gtctgcaagt gtttaaaact  15900 

ctgcatctga tctggcagtt tcactgtaac gctacaattg acctgcatat atctcaatag  15960 

aaccagttga taaatttctg tgaggtctat catgtttcca tcttcacacg aaaaatcaag  16020 

acatgcaaca cgaagaagct taaactcttt aattgaaggc atgcagttaa atagcccaat  16080 

aaatataaaa gaccgaattt ctgatagccc aatattaacc ggtgtagtag catatgttgc  16140 

actgccgaag tgtagggaca atcgatgaac cttgtaagta agtcttactg tcgtttgaga  16200 

ataatcaatt gcagtgacaa aattctcttc ctgggccttg cgtgtgataa attcatgtac  16260 

aatatggtga actgcatagg tcaatatgtc agatttatac ttgatatccc tacattggat  16320 

gagtcccaga ttgacaagct tattgaaata actcatggca acttccatgg cattttcccg  16380 

tgttgacgag cagacaaaat cttgggctat ccattgattc accaaatctt ccttcaaaag  16440 

tatgtagtta tccggatata cactaagata tagcaaacat gtcttcaaac aacaaggaag  16500 

actgttgtag caaaggttca gtacttgctt cagtatctca tcagaagtag catttaccct  16560 

caaattattg cacaagaaat tttctacata ttgccagtac ttcaatctat cttccaagtt  16620 

ctgtactgtc tcatgttgga ttgctagaag actgcccatg atgataattg ctagtggtga  16680 

gccaccacat tttcttgcaa tctcttgtgt gactttgtgg aattgaccgg gatgctctcc  16740 

agagccaaaa gttctactga ttagcaactt cttcgactcg tcgacactaa gagctttcat  16800 

cttgaatatg tactgagggt tataaacgca acaagccaga gcaacttcat caacttttgt  16860 

ggttgttatt attctgctcc cacaattatt cacaggaaaa gcatgtctaa caacatccca  16920 

tacggatgga gcccataaat catcaattac aataaagtac ctgacaaata atttggtctg  16980 

tatcagacgt gttttgtcaa gcaaaagaga aaatatccaa gaaaaatatc atgacaatgg  17040 

atttttgttc taaaaaacaa aaagaagatt tgcaaacctc ctgtttttta gatgattctt  17100 

gacatcgtcg atgaggttgg tcacagcaca agggacgact ggttggagcg gccgaacttg  17160 

agagagtata ttcctcagaa tcatccttat atcaggcttt ttggccgtct gcacaaaagc  17220 

ccggcactcg aattttcctt caagttcacg ccatagtagt tcggcaagct tggtcttacc  17280 

gattccttca gcaccgagaa tgcataacac cttgagattt tcatcttcgt cttcagccat  17340 

ccaaccacgc agcttgtttc tcgggccatc catgccaaca gggtcaacaa ccttgctgaa  17400 

cacagttgga agatgatgat gtacaaccat gtttgtggga cttgatccag catcagcatc  17460 

aagattatag atgctccatc gctcattcgc ctccttgaca agagtcaaga atcctgagat  17520 

ggtgtcatcc caacccatct tggcaccagc atcagcgttg accaacaagt cgatgcagtc  17580 

ctccatgtcg tagcaaagct cgcgcacatc cttcatccag taaatcaccg tgagggatgg  17640 

atctcgcaca tttgaaagct tctccaaacg atcttgtatg acgctaagct cagatatgag  17700 

ttgatggata gtcgggctat cgagctcctt caacttctgt agaagggagc ccatggcacc  17760 

cagcgaagcg ctaatcggag cttccattct tgtttctgcc tgcagttgat caaaagggaa  17820 

cacatcatga gctgctatca gccagaacct catatggacg aaaatcatga aataggaggt  17880 

aattcattgg aaagaaaaag gaacatcatt aatcgaaaag aaaaccgcag ctaaccatga  17940 

gattatgata tgttagggga gacacggcag tactgcaaag gtacgacagg agttatttgg  18000 

agagtgattt ctctcttctt cgttttaagg gcaacgaaga acaacaatat atcctgttcc  18060 

tcgctccgac ctttacatgt ccaatcccaa cagctccgat acccccacgc atgcccacca  18120 

ggcacccata caacagattt tgtttatact caagt                             18155 

 
           
             11  
             2921  
             DNA  
             Oryza sativa  
           
            11 

taggagaaga tggaattatt ctaattgatt agggttccca caacaactag ctttcttctt     60 

aattgttctt atgcacgcct tctccatgtt accattattt tttttaagag aaaggccgta    120 

cggcccggct tctattgaaa gccagaggat tgtgctggga acacccagac accagtttat    180 

agcataggga ggttcaaagc cctccaaaag gaaaacatga aagactccca aacttgctac    240 

cagctctaaa agcaacaaaa taagcagaaa gaaaccaaaa ggctgtcctt acaagtagcg    300 

tcatgacagc aaaacggaag acaaacccct acatcctaaa tttcgtctca tcctagtttg    360 

tggcatctca agaaaggaga attgttctgt gcaattatag tttgtggcat atgttcattg    420 

tgtttccatg agtaaaacgc cctgttcttt ttttttttct gaccaaatgg attgcgaaga    480 

aaaatctact acatagctta gtcctatcgg agccgctctt cactgtgtat tgtgacattg    540 

tgtcaatata atgagacgaa agaagcgtct ctctatgcca atgaacaaga cgaaacatgg    600 

cttagtccta cccttacaac ctgaattcca ctcctcggag tcgaggaact caaatcgttc    660 

ttaattggaa gtccacaaat ttcataaccg aatcaaaaat gcagctaaaa caaatttcat    720 

gacgtgaaga tggaattact catctgtcgg gtcaacaacg tggccggcga agagcaccgc    780 

acccgacgac tcctccaaaa ccaagaacgc gaacggatgg tcggcgacga aatccaccct    840 

cgccggccgc cgtgacgatg gcgccgccga tgcgaaggta agacaaaccg cggtggcggc    900 

ggccgctcgg tgccctcctc gttcacctcg atgacggcct tgtgcttgac gtccgacaca    960 

aacagcggcg gatcatcgcc agagttctcc gcttccagca cgtcggccag gtccgccacg   1020 

aacggcttga acacgtccct gaccccgaga cgctggaggg cgcccacgac gctgtcgtcg   1080 

aaggagagct tgaacctggg gatcctgaac tcgccgacct cgacgcgccg ctccggcgtg   1140 

tgctcgcgga ggaagccctc gccgccggcc gccatcctgt cctccaggct ccacaggccg   1200 

tcgcgctcgt cggggaggaa gacgtacatc gagtacctcg gcgtcgtcgt cgtcctcgcg   1260 

ctcacacaag ccgcgtacgg catcttgagc accttgaacc cgtcgtgcac ggcgatgtac   1320 

tggtcctcgc cgctgcgcat gaagtccgcc tcgacgtcgc cgccgtcgag gcggtggaac   1380 

gcccgcttct cggttatctc cttacagaaa ggagtccgcc attggccgtt gaagtagatg   1440 

gcgctggtga ccacgaggcc cgtgtccgtg ctcaccgacc ccggcgggag gatcgtgtcg   1500 

atgaggttct ccgtcgccgc cgcaacccag ctgttgatct ccttcctcgc ttcctccggc   1560 

tacacgcata catgacagat tagattggta gatcttgtca tgtgtatata tatatagttc   1620 

gcttacgttg ttgaggaagt cgacggcgag ggccgcggcg ttgaacgacg cggcggcggc   1680 

gtcgcggaac gccggcctaa ccgtccgcgt ccgctcgtgc cagactccgc acgcgtgcgc   1740 

gacgcgcggg ccgccgcccg gctgtgccgc gccgccgccg ggggcgggga gagcacgcgc   1800 

catctcgccg gcgttcgcgg cgagcttctc gcgggactct gcgccgaggg cgccgaggag   1860 

ctctgtcagg gtgcgcccgc gcgcgccggc ggtgaccacg gagagcgcgg agtagatgga   1920 

cagcggcgag aagacgaggt tgccggcagc gccagccttg ctggcggcgg cggcggcgga   1980 

gagctgcttg gtgaggcgca tggacagcgc catcaggccg gagacggcgc accgccgtgc   2040 

acacgattcc atggtggaaa aaggtgttcg acgcctgtct cagagatcta tttgcacaac   2100 

tcgatcacaa gacgtacggc ccaaggcttt tatagaacct ataatccatg aatgctgaag   2160 

taataataac atagggcatg ttcactttga tgcaaaataa gaccttacca aaatttggca   2220 

ttaccaaaac tttgatatag ttgtcaaaat tttgacaact tactaaaatt ttagcaggat   2280 

ttcttatata gttatccaaa tttggttttg ctaaaaattt gtcgacaaat tttttttttt   2340 

agaaatctcc cagattttcc accgtctaaa ttgcattatg atttgtgcta gctgccgtta   2400 

caaccaaaaa aaaggactac tgtaacctcc gtgggagtcg atcccaagat ctgatgcttt   2460 

gaacgtgaaa taactagctg agcaagaagg agcaactaat tgtttcacca aaacaatact   2520 

tacttatact gtattagtta tactgtatgt acatattaat tatattataa ttgcactata   2580 

attatatata ttagttacat tgtacttaca tatcactggt ggagaaacca tctttcgtcg   2640 

gtcggccgat ttccacaata gtcccggatg caataaaaac cggggctaaa gatgatcttt   2700 

agtcccggtt caaaagggta acgggcatat ttgatcttta gtcccggttt gtgttaccaa   2760 

ctgggactaa agatcatctt tagtcccggt ttgaatgctg tcagggcctg tcaggccccc   2820 

ccgggatctt tagtcccggt tggtaacaga tcgtaacttt agtcccggtt ggtaatacca   2880 

accgggacta aagatcccgg tgatctttag ccccggttgg t                       2921 

 
           
             12  
             10883  
             DNA  
             Oryza sativa  
           
            12 

tggtactata aaaatttatg ttgttatagt gggtaacatt atcatggtta tgcgtgagaa     60 

tggcatactg tctcctgcgg cacaccctcc ttggtggtgg ctgtgcgata gggtggggcg    120 

tgacaacaac gaagtagccc aagcttagaa ctgctattgc cagcgacgac gaagagagtg    180 

aaatagacac aaatgattgt tgtaggaagc tcgacgctct agccccctga tctaaactca    240 

atgttgtcac catcgaagga aaaaaaatgc agacgatcga cgatgacgaa atcacttcca    300 

aaacaggccg taatcatcta gctcatattc cctctatgga agtggagatt gcagctgtga    360 

tctagaccat atggaaagcc aaaaatgcag catgttttaa aaacaagaaa tctcatgacc    420 

ctactgagct aatacataaa gtatgttttt cattgaattg tggtccattt tgctgatgtc    480 

ggaagacgtg caaagaaagc tacaaccagg agtggcaccg ctaagaaggg tgcactacta    540 

gaaaacacct aatatcctat aggtgtcagt ttatttaaaa ccgacaccta tttccttcta    600 

actgtaagag atagatctcg gccatacatc atcacgtaaa atttaattta tacccaaact    660 

cgccataatt gtcatctcta ctacccaaat aatgtacggg gagtaaaaat ggaactccca    720 

agaccaatcc ctccatcaac ttcctccttt caaaccccca atcctcttct cttggcaaac    780 

atgccgctag ggtttggaag gatgcggggg ttcgagggca aggatagcgt ctatattacg    840 

agcggcctta aaaaggttgg acatttgcgc ggtacaccaa actagttaat ttgatgaggc    900 

ctagaatgtg agggccccaa gacgaaggaa tgatgcctca gataggccca tcacggggat    960 

caacttattt tattgtttta gtctctctgg tgacagattc ttcttcgaag ggagtttggc   1020 

caaaaaaagc atgacgacac gacgagtaac ttgattggat tgagcatgag ttttgtaggt   1080 

cggttatttt ctttcattat tttgaagaac aaatggaaaa ctaggcatga catgacaatg   1140 

gaataaattt gagcttgtgg gaatcacatg agaatacccg aaatatacta ggacaacaaa   1200 

tgtttgatag agtttagaat tagttgaaca agagatatat tccaactacc gatcaaagaa   1260 

cttggcataa cgtatgggaa cgtattctgg agcctagatc gttggtgttg gggatattaa   1320 

tccaccagcg agggaacgac tcggtgtgac agtacacgcg actgtaactt tcagtattgt   1380 

gtgatataga gtttgatcat caaagttagg acaagaatgc aattgtccaa tgggaaaaca   1440 

aactcttaat tagcttcaga aattcccatt tatattaact tcaacatcta ccacccttac   1500 

aagatagctc atataaccat aacaactcta gcattatgct attcagacag gtagcattag   1560 

agggtacaaa aacggaagat atggacattt gacatctgaa acagattcat tttggctggt   1620 

tttcacatga cagcttgttg gtcttcgtat gatatatata tatatatata gcgtctcgac   1680 

ccttctcaat cttaaaactc ctgcttttga gaaaggaaat taattagaat gcaggctata   1740 

gctctgaaga agccccataa tgaaagagaa gtacacagac gaagaatcaa aggtgcaacc   1800 

agcgagcata caaattaaag caaaaataaa gtatcagatt tgagcaaggc aattttgtat   1860 

aaattttttt ttgtcccagg aaaatggtta aaactctaca ttgcacccaa tttatgttac   1920 

ttttcgatac ggtcaggctg ctgtaaatca acattcacac tgctactgta ccattacatg   1980 

aacataaatc atgacaactt acagaaacta tagctggttt atgcgctgta gctgttagcc   2040 

tgtgagagaa aattcacttc ttaaggtcca ccaccctaga gtttctcaat gaagagctta   2100 

ataagatcca ttgattacag aaaaacagag acttgaatag aaaaccgttt ttggctgaaa   2160 

aggaaaacaa aacaattctc caactacttt gcttcaagaa aaaaatacac agaaccgtaa   2220 

gcatcaaagt gcaaagttga taccatattt atgaaattgc atttataggg agtatttgat   2280 

ttgtcaacaa acatgattga cgttagctag cctgaataaa ggccatttct gtgtcaaaat   2340 

caaactactt tacaagtgct tagcaagcga tcaatacagc aagcaatcaa caattgagaa   2400 

ctcatgattg tgaagccgcc acacgataga aataacaaaa ctaaactgcc agtatccaag   2460 

atatatatga tcggggtatt tactaatcag tacacaaata tttctcttta agtaaaacta   2520 

gcgcagataa taattaggta gttcaaaaat gcatttctta ttcatcctaa ccattgtttt   2580 

atagcaggct aatttagcgg ttggccctct caacagttat aggggcatct atagcggcta   2640 

aattatacgg aagagaaaag agctaaaact cttctcaaac agatataacc ggacatagcg   2700 

gcagctatag tcggagattt aaaacaaccc tgatcctatc acaacatgga attcaaggtc   2760 

aagccagtac actaactgct tcacgagtga gaagccaact gagaaataat taacacttaa   2820 

tttgccgatt ccaaaaaaga gtcacaggaa gtacaagata ggttactact actccctccg   2880 

ttccaaaaca cgttacattt tgggacagat caagctaagg gcttctccag ttaatgcact   2940 

cgatccatgt ctatcagaaa aacaaattaa aatatacatt gtatagatga aattgggaat   3000 

acataccttg tactccatgt cagctatacc tgatgccaga tcccctgcgg aacaagataa   3060 

gacaggacca tttcgaagta cccaccatca ctcctagctg gcatacaaca acacatccga   3120 

gcaagttctt cctggttcca gtctgaaaac tcattcaggc caaaacgggt cgagtgccct   3180 

gcgttggcag aatcatcgtt ggctgcatca gaaaatcttg caactgactt gaatattttg   3240 

aatcgcctag cctcctccac ctcgtcctgc ttgtatgtcc tgccatgctc cttcatccaa   3300 

tccttgaacc ttgcccttat gtcttgatca tcctccatgt actctcgaac cacggtcttc   3360 

tcgtcaggcg ttgtttcgtt gtaagacgcc ctctctcgta tcaagtcttc catcaactgg   3420 

ttggaacgga agtaaggatt tgtcttagtg ggtgtgtcct ccttccgagc ttcgtctacg   3480 

tacagacagt atgaactcgt gagggttgag ggcaatgtaa cataaaagga aagcttcccg   3540 

gcgaaaaaca taaaaggaaa gctaaagacg agaaatctga agggtgttta acatgtagta   3600 

tgaggagtgg gttctaatct cttgaggggt tatcccttcg tgtgtgcttt ttttttcaaa   3660 

attcgataca aatagttgtg aaaaaatctg aaaaaaatat cgacaatgta gagtacagtg   3720 

atatgtatcg gtccattaaa aatcaagttc aaattcaatc tacacatcga aaagacaaaa   3780 

ttagacgtga acagtacatt gctattcata cactgaattt gtctttctta tacgtcgacg   3840 

tgtgacttga gtttggagcc aagattttat aaagttgtat agatattttg tatgagtgtt   3900 

gtcaaaattt tccagaattt ttcataacaa tttggatgac ttttaagcaa acgagggtac   3960 

attcttatgc gatcgaaata atttcccata accattgatg gttatatatg aagagttttt   4020 

ttactgtcca gcagtgaagc ccggtaccaa atgtggaccg ctggataggt atgatcggat   4080 

ggctgacatc aattggtacc ttcaagtacc atttactccc tacgtggtac ctgccaaagg   4140 

ggaatgaggt ggaggggtaa aattgtattt gcacattgga aaggaatttc gtcgatttga   4200 

ttcgtgtttt ggataaggct ttgcagagga aaatctacgg cagtggcggc gagccggcga   4260 

cgcttcagga attacggtgc gctccaccag tcttctgagg ccacaacggt gctccaggag   4320 

ttgttgtcag cggcgacaac ggcagcattc caggagttat cggcagtgac ggcggtgctc   4380 

cagggatcat ctgcaactgc ggtggcagcg ctccgataat tgtcttcggc gacgacggca   4440 

tcactccacg ggtcattgct agcgacgacg atggttgatt tggttgaaca gtttttgagc   4500 

aagaaagata catacaggaa taaattgaga agcaggaagt tccccgcaaa aaaaaagaga   4560 

agcatgaagt tgatttgcct aaatggcttc aggttgattt gtcagacaaa cacaaaatca   4620 

atactcatgc gaaaagctcc aacacaacct ccattccgga acaattatag ggtgcagact   4680 

acagcggcgg tggcgacaaa gtccggcgcg tcaggataca tgttgcggca gcgtcggcca   4740 

tcggtcccac tgtcgttgcc gcagagcaag gacacgctgg ggctgggggg aggacaggca   4800 

gcagcgacgg cggtgacaga gacgtgcgcg acggagcgag ctgaggaacg atgtcatgcg   4860 

tcaaggagag cagaatgcga cggcagcggc gactcggata tgcctgtgaa gatgaggaga   4920 

tttcgtcgtc gcacgctagc tggctgcttt acttcatttc caatcgtacc ccagtttatt   4980 

gaacggccgg atttcgtttg gtacctgtgg taccagtacc tggaggtacc aactgctgga   5040 

ccagaacaaa gctcatatat gaaacatgca gtcaaaggca gctagtttca catggagtac   5100 

ctaaaaactc acctgtatct tgcatcaaat gcaaaattcc agcaaccgca gagaaaacaa   5160 

caacagacaa cgtagcggta gcagcatcgg catgttccaa gaccacatcc ctctgcacca   5220 

cgaggattca acgtgagctt atctggaagt aaaacaaggc ttagatagat aaacgatgaa   5280 

ggaaatttac caagtcgtgg aaccggcgtg ctctcctccc cgccggcgac cccagagacc   5340 

cctgcacaac gatgaattaa cgaacgaaat aacgggagca agatggaaac acgcgcgtga   5400 

atgtgtgtgt ctgtgggatt gaaaaaggag ggaaacacac acagcaagat ttgaaagaaa   5460 

tttaccatgc tgtgcagaca acgggatgat ctggcggcga aagcagaggt gttggccgcc   5520 

acaagactct tacgacgggc atcggagtag aagaacagcg cgttcctctg cgagaataat   5580 

tatgagccgc tagcggagaa agcatacgat gtatagatct gagatgagaa aagatcaaaa   5640 

gaagcagatt actactccct ccgtctcaaa ttataatatc tatatttttt acacgatttt   5700 

caatggcata ttttgactat tggtttattc atgttgcgtt attaacgaat ttgaaattag   5760 

agtgaaaata tgaatctagc gatatatcat gtattatgat taatataatt attagttaaa   5820 

agtttctgag tttgatttac cagggatagt agacgattag cgattcccga tcccggcgag   5880 

gaggaggaac agcggatact cccgcgaacg agagagccca gcagcgacaa cgacctaaaa   5940 

cccatatgcc taccgctcgc tcgatctgtc tccccgctgc ctgtccgatc gatcgccgcc   6000 

tcaaacttgt agggttttgg aaagatgcag agggcgctcg aggcgtcgag gtccacgtac   6060 

ggggccctgc ccgaaccagt ttttttttta aaaaaaaatt acacagtaca acgcagatac   6120 

tcacaacgca cgcgcactga cccctatgaa cacgcgcacg caaaccctat atctatgagc   6180 

atcttcgaag actggactgg caaatcttgg agagattgac gaagtcacca cgggcgcctc   6240 

gctgtcgacg ggtacgtcgc ctaccactga aagcacaatg ccgttaaatc ctgaaaaatt   6300 

cgctcccacg gggagtcaaa cccaggacct caggtgctac tgagactctc ccgcccgaac   6360 

cagtttgatg aggcaggcct atgatgggtt caattcagat tcagggtcgc cgcgccaaat   6420 

gtgtagtttg ccaattgacc tggattcgtg cgtactactc catgatgtat atgcagcttc   6480 

ttgttgctta gttacatgct tccttcgact tgtgtacaga ttattagatt gcattatgtt   6540 

gcttcacgat gacaggacct agttaaccga tcaattagta gattgaaaac gattttctga   6600 

ctcgatggcg agtgttcaat tacatgtttt gaaagcattc aagccagtcc gaaaatattt   6660 

ttgttttcta aaaaaacaac caatgatcga aagattgcac accaatattg tttgatgcca   6720 

attgatctac tgatccactt gccacatagg gcagctatta ctccctctgg aatataaatg   6780 

caacctaata caaatgtaat atattatata actataaatc tagataacta tctctccaaa   6840 

tttatagtct taggatatgt cgcatctcta ttacactaca agaaaaggca tttttgccga   6900 

tgttggatac ttattttcgc aggtggacat aaccttcgga tacaaatagc cgtctacgaa   6960 

aatgtaaatc ggggtgaaac ccgctgcccg cctgcgaaaa tccatttttg catgtggacc   7020 

acttaaacgg tcttcctgca aaaataccct tcatttttgc aggcggacct ccgcctgcga   7080 

aaatacatag gaaatataaa tagaggctgt ataccctaga tttttttcta agtcctcttt   7140 

gcctcacctc tcccctcccc gcacctctcc tcctctcccc ggcgctgatg gcagcggagg   7200 

gcggcggcta ccggtggagg cggcggcgga gggcggtggc cggcggcact cccctccctc   7260 

actctctccc agatctggcc tgaggggggc ggggggaagg cggtggccac gcgtacggcg   7320 

gcagtggagg gcggcggcta ccggcgggag gcggagggtg gcggcgagcg gcggcggagg   7380 

agggtggcgg cggctcccgg cccctccctc cctcccagat ccagcggcgg agcatgctac   7440 

tgtactcttg ctctattatg tacacaagca aaaatttcca tctcgaatgt aatcctttat   7500 

ttttgttgca cgacagcaca tttgacaatt acaatcacct caaccaatcc tatgtgaacg   7560 

acttcgatga ccagtacaaa tatcactaga aagagcagca tcttagactg tgtttagttc   7620 

acaccaaaat tggaattttg gttgaaattg gaacgatgta acggaaaagt tgaaagtttg   7680 

tgtgtgtaga aaaattttga tgtgatgaaa aaattgaaag tttgaagaat aatttgcaac   7740 

taaacacggc gttaatgtaa aactgcttaa acgtttcgct gaaacctgaa tagattttcc   7800 

ctcactaaaa gcacacagct ccagtactct caactgaagc cagcgccttc ttgctgatcc   7860 

agtagatctg agtgagccgt cttctcatgt ctatatgaat gcctagcatg tggatgatgg   7920 

gaacatagtg cctccacacg gaaaacagaa cgatctatta gcacgtgatt aattaagtat   7980 

tagctaattt tttttaaaaa aaatagatta atttgttttt ttaagcaact ttcgtataga   8040 

aactttttat aacaaatgca ccgtttagca gtttgaaaag cgtgcgcgcg aaaaacaagg   8100 

gatttgggtt gggaaactag aggtccgaac acacccaaag caattttcta tttcattcac   8160 

cctaaaatat agcaaacgta gaactagcca gtttaaattc atactatagg gtagatatcc   8220 

aatttaaaac gaataaaagg ctcaatttgc tctctagttg ccacgaccat ttaagatcca   8280 

tgcaaatttc attacagttg actaggatta gtggggtcaa cgacgtggcc ggcgaagagc   8340 

accgcacccg acgactcctc cactacaaag aaggcgaacg gatggtcggc gacgaagtcc   8400 

accggcgccg gcgccggaga tggccgcctc gccctccctt tcataataac caccgtggcc   8460 

gccgccacct ccgtgccctc ctcgttcacc tcgatcgctg ccccatgcag gacgtccgac   8520 

acgaacagcg gcggatcgcc ggagttgccc tcctccagca cgtcggacag gtcggccgct   8580 

gccggatcga acacggccct gaccccgaca ccctggagcg cggtcttgat gctgccgtcg   8640 

aaggagagct tgaacctggg gatcctgaac tcgccgacct tgacgcgctt ctccggcatg   8700 

tgctcccgga ggaagacctc gccgccgccg gcctccatcc tgtcggcgag ggtccacagc   8760 

ccgtcgcgct cgtcggggag gaagacacac aacgagtact gcggttgcgt gtgcgtacgg   8820 

gaggcacgcg tgttgtacgg catcctgagc accttgaacc cgtcgtacgc ggcgacgtac   8880 

tggtcgtcgc cgctgcgcat gaagtccgcg tcgacgtcgc cgccgccgcc gaggaggtgg   8940 

aacttgtcct tcttggtgtc ctgcttgcgg aatggcgtct gccaagtggc gttgaagtag   9000 

atggcgctgg cgaccacgag ccgcgtgtcc gtgctcaccg accccggcgg gaggatcgtg   9060 

tcgatgaggt tctccgtcgc cgccgcgacc cagctgttga tcgcgttcct cgcttcctcc   9120 

ggctacacgc gtcgcgcatg tccgtttcaa tggagatcgt cattcgttaa tggcgtgaca   9180 

ttagattgat atagatcgat gattcgatca cttacgttgg cgaggaagtc gacggcgcgc   9240 

gtcgtgcctt ggaaggacgc ggcggtggcg tcgcggaagg ccggcttgac gttcctcctc   9300 

cgatcgtgcc agaggccgca cgcgtgcgcg acgcggggcc cgcccgtcgc cgtgccggag   9360 

ccgccgggga gggcgcgcac gatctcgccg gcgtcctcgg cgagcgcgtc gcgggaggac   9420 

ggcgcgccga gggcggcgag cagctcggcc agggtggtcc cccgcgcgcc ggcggtgacc   9480 

acggtgagcg cggagtagat ggacagcggc gagaacacga ggttgccgcc gccgacgctg   9540 

tcctcctcca aggacagacg ctcggcgagg cgcagcgcca tccccgccag gccggaggcg   9600 

gcgcaccgcc gcgaacacgc ctgatccgtg gctgaactgt ttcctccctc gcttcttgga   9660 

gagcccgatt ccggtcgaac accaccagtc caccaccgcc tgcttccacc acggcgagcg   9720 

atctccccga gacggcggat catcgagcga ggcgagagga gaattcgagc ggaggaggag   9780 

gaggaagagg atccgattcc aggagaggct acacagatca gaaacgcgtg gaaatcacga   9840 

accaatcttg cagaacggaa gagagaaaaa aagggggaaa aaattaaacg tgggggaaaa   9900 

aaaaaagata aaccaggaat ccggccggga gcacgtacat gggaagcggg gctggagctg   9960 

gtcgtcgtgg aagagctcgc cgccggcgag cacaagcacc gcaagcacgt agacgaggaa  10020 

caacacgacg agaccctgga tcgcgcacca ccgccggcgc ggcgccccgg ccgccggtgg  10080 

agtcgccatt ggacgggagg agacgcagga aagttttact actggtagta ctgtagtagg  10140 

gacgaggaat taccgggggg cgtgtgaatg tgggcgtgga cgcggtgtat gcactcctct  10200 

cacgtgcaat gagagactcc aaggctaagg tattgtcatt tagagcgtgg accgtgtcca  10260 

cgggggataa acgcgtggac aggttgtgac tgctgctgtt tcggtgagca attgggcatt  10320 

ccgttgggtg gtgcggtggg gccacccttt tgacctgtct agtactctag tcaacacctg  10380 

aggttgacct gtttagggct gtgttcacca ttgcttccct accggtgtac gtacggaaaa  10440 

cggaacggtt tattagcacg tgattaatta agtattagct aatattttta aaaaaataga  10500 

ttaatttgat tttttaagca actttcgtat ataaacattt taaaaaaata caccgtttaa  10560 

cagtttgaaa agctcgcgca tagaaaacga gaggagggat taggaagagg ggcagccgaa  10620 

gacagccaat tgtttgcttg ccggtatagt acgaaaaacc atgaatcggg cacctgggtt  10680 

tacggggtcc gctggtcaaa ctatgaatcg agcaccaggt ggttgaaccg cggttcaatt  10740 

tttatatata atatatgtta aagctataac gcaactgcta ggacagccgg attcatgtga  10800 

ggatatattt ttttcatttt ttgccaactg agtgtgcatg gcagactaat tgggccacat  10860 

taaggccatt aaacgactgt tgt                                          10883 

 
           
             13  
             1957  
             DNA  
             Oryza sativa  
           
            13 

ttttttttgg gacggataga aatagacatt agcgttaaga ctcgagcaat ttccaaaaac     60 

aatgatacta tacttctgtt gactaagatt tcgtcgggtc aacgacatgc cccgcgaaga    120 

gtaccgcgcc cgacgattcc tccaccacaa agaaggcgaa cggatggtcg gcgacgaagt    180 

cctcccttgg cggcggcggc ggcgcatacc gcgccgcacc ttccattaac actgccgtgg    240 

ccgccgccgc ctcggtgccc tcctcgttca cctcgatcac ggccttgtgc aggacgtccg    300 

acacgcgcag cggctcgccc tcgatcatgt ccggcagctc ggcccgatcg aacacggcgt    360 

tcaccccgac accccggagc gcgcgcacga cgctgcggct gaaggagagc ttgaacctgg    420 

ggatcctgaa ctcgccgacc tcgacgcgtc gcaccggcat gtgctcgctg aggaagccct    480 

cgccgccgcc gccgccaccg gccgccgcca tcctgtcctc gaggctggac aggccgtcgc    540 

tctcgtcggg gaggaggatg tacatggagt agtaccgcgg cgagggttgt ggcgccgcgt    600 

ggtcgtgggc gtacggcatc ttgagcacct tgaacccgtc gtgcgccgcg atgtactggt    660 

cctcgccggt gcgcatgaag tccgcgtcga cggtgccgtg gccgtcgagg aggtggaact    720 

tgtccttctt ggtgtcctgc tttcggaatg gcgtctgcca tgtgccgttg aagtagatgg    780 

cgctggtgac cacgagaccc gtgtccgtgc tcaccgaccc cggcgggagg atcgtgtcga    840 

tgaggttctc cgtcgcggcc gccggcgtct tccatggtag tcatggtgat agctattgat    900 

tggattgata gttttcgtag aagttgaata actattttca acttattttg ttctttttgt    960 

tgcaacttgt agaagttaaa tttggtcttg cataattgta gagggatgaa aatccatatc   1020 

ctatatatag acgatgtttt cgcgctacta attttggacc ccctggcaag caacaatctc   1080 

cctcgcaatt ttcaggtttt ttagtaattt ttatgaattc aaatttagta aaaatagtta   1140 

aatttcaaat attttcgtgt aaaaaagttt tgaaaaaacc gaaattcgtg aaatttttgt   1200 

tgacactgaa atcacataat tttttccctt ccttgtttgc acaaatcttg aaacaaatct   1260 

aacagttcaa aattatataa aaattactcc ctccgcttta tatgataagt catttgattt   1320 

tttttcttag tcaaattttt taaagtttga taagtttgta gaaacatata gtgatatttc   1380 

aaatacaaaa caaatatttt tttaaaatat attcaatgtt ggatttaatg aaactaattt   1440 

ggtgttatag atgttactaa tttttctata aatttgctca aacctaaaga actttgacta   1500 

aaaaagtaca ttacactatg tacgattgta ctataattat atttgtcaac tttttaaaag   1560 

aaattttgtt gataaatatg taacaaaatt gaaactattt acaaaattcc accgtgaagc   1620 

gtacatctgt tcaaggtatg tgcacggcta taaggtagat gcaaaataat tcgagttcgg   1680 

atgtatcctt gatcacctca aggggattta tgtagatgcg cgttcttgcg gggtatgaaa   1740 

tgtatcttac caagttaaac ccgtgatatt tacttgcgtg tgtcacgttt gtatatgcgt   1800 

ggtcggacag gaaaagatca aagtaccaaa tatttacaag gtgtggcaac ctttacttac   1860 

cgcgcactct agcaatttac atagcacaaa acagataaca tagagttaga gatataggac   1920 

gatgacatga aaataatttt tcatgtatta tatgact                            1957 

 
           
             14  
             6823  
             DNA  
             Oryza sativa  
           
            14 

tatatatata tatatgttac ttcgcattta tcctaataca tctttttgta tcttgcagaa     60 

aagacgtgtt gtcggagtcg tccgtcaagc ctgagtggaa gagctagccc tagaaggaat    120 

tggagcaggc aagtgacgta ataatataaa tgattgttat atttgtaatg caattaatta    180 

agattattag acctgtaatt ggacttatca tataagattg tgtagtgttc taatattatt    240 

tgagttttaa tataagatta ctttatttgt aattagactt agtatgtata attattgact    300 

acggaattgg tgcgacaagt agcaattgac tattgtagtc ttaattagac ttagcatata    360 

cgcacgaaac acttagcata gatgactatt ttagtcttag catgtaatat tatttgagtt    420 

ttaatataag attactttat ttgtaattag acttagtatg tataattatt gactacggaa    480 

ttggtgcgac aagtagcaat tgactattgt agtcttaatt agacttagca tatacgcacg    540 

aaacacttag catagatgac tattttagtc ttagcatgta atattatttg agttttaata    600 

taagattact ttatttgtaa ttagacttag tatgtataat tattgactac ggaattggtg    660 

cgacaagtag caattgacta ttgtagtctt aattagactt agcatatacg cacgaaacac    720 

ttagcataga tgactatttt agtcttagca tgtaatatta tttgagtttt aatataagat    780 

tactttattt gtaattatac ttagtatgta attattgact acggaattgg tgcgacaagt    840 

agcaattgac tattgtagtc ttaattagac ttagcatata cgcacgaaac acttagcata    900 

tacatgacta ttttagtctt agcatgtaat attatttgag ttttaatata agattacttt    960 

atttgtaatt agacttagta tgtaattatt gactacggaa ttggtgcgac aagtagcaat   1020 

tgactattgt agtcttaatt agacttagca tatacgcacg aaacacttag catatacatg   1080 

actattgtag tcttagcatg taatattatt tgagttttaa tataagatta ttttatttgt   1140 

aattagactt agtatataat tatttactag ctagggttat ataatatacg tcacctagac   1200 

ttagcttata tcacgatttg taattagact tagcacgtaa ggttgtgtag ggttctaatg   1260 

tacgacattt acacttagca tacatgactt agattgttaa aacataaatg tctcgtgact   1320 

tagcagatgt ttcttgtatc aacagatggc tgaccgcgat gaggaacaga tattgtacga   1380 

tacaatcgcg gagggaagca gccagtactg gaatgaagaa gaggggaacg aggatccaaa   1440 

ccagtacttg aacgaggaag ggaacgtgga gagggatgcg gaggggaacc agcaggggca   1500 

cgtggaaagg gatgtggagg ggaaccagga ggaggaggct agtggtagtc aaccctccgt   1560 

tggacagaag agggcacgcg ggcaacgagg tgcagcgaag aagcttgagg gtcggcacat   1620 

cataacggaa gtgcaagaag atggacgtcc tagtgccccg gccgaagccg ccaagaacta   1680 

tgtacgtcac agcggttggg ttgtgcggga taacgtgcct gtcagtacgg tgtactggcg   1740 

aagaacaagg gcacgcggag atcatgagag ctttgtccca gattcagaga aagagatgct   1800 

gtggaccaca atgctcgaga cattcaccct tcctgcgggt acagaggaca aagtgaaaag   1860 

gtggactctg aagaaaatgg cagaacagtt tcagagcttc aagggagatc tgtaccaaaa   1920 

gtatatactg aaggggcaga caccgaactt cgacacattc ccaaagctaa gggatcactg   1980 

ggacgagttt gttgcatata agacaggtga acaagggcag gcgatgatgg aaagaaacaa   2040 

agaaaatgcc gccaagaaga agtaccatca ccacttgggg tcaggaggct atagcgtcgc   2100 

gatgccgaag tgggagcaga tggaggctag cttgattgag aggggtatcg aaccggcaac   2160 

agccaattgg ccggaacgat cgaagttctg gtactatgct cacggtggaa cgctcaaccc   2220 

agctgatggc tcactggtct tcggcgatca gatacgagag gctgcgcgac gactaacaga   2280 

tgcagtggaa gcctcctctc agggcacgtt ccgaccagac agagataggg acgagctgac   2340 

actcgccctg cagactccag agcatccagg acgaacacga gggaaagggg tgattccttg   2400 

gaagattggt ttcaaggagg acatccacac gtacaggagt tggatgagga gcaagagaga   2460 

taccgaggcg aagattgcag acctagagtt ccaggtatcg agctacgaac tcaacatgca   2520 

agaggaggtg gcaaggaagg ttgatgaacg catggccgca catcggtccc atgatcccca   2580 

gctgaccatt cctcctgcaa tggtaagcct gtcaggaaac cgtagcagct gcgcctcaac   2640 

ggggcaggta ggatcacaga gcatggacgc catgcaaaca caggacgaat cgacctgtcc   2700 

cgttgatgac atcactcaac ggacaccatg tgagctgcat attcctttca agaacttatc   2760 

aataaaggta tgatttagcc attccgctag ttgctgctta tatatgttga ttactaataa   2820 

ataatctctc acaacatgaa ggtggcgtcg ggcatggcca tcccaacgga cccttcaggt   2880 

acttaccact gcaggccgat tccagcagga tactcgaagg tcgaagttga gttggtcgaa   2940 

ggcgcgtacg aggacctcga gctggattac cctggaggag acggtgagac gcatctacga   3000 

gaaacaagcc atgccattat tctatgacgc aggcggtaca tcatcctccc tgggcgacaa   3060 

gcggcgtctc gtgcaccatc tcctcctcag gatcctgcac cgtctcctcc tcatgctccg   3120 

atagcaccgt ctccacctca ggctccagca tcgactcctc ctcaggatcc tgcaccgact   3180 

cctcctcgtg ctcctacacc tactcccccg caagctcctc ttccggcacc ttcaaagtca   3240 

agggcccccc cagctccacc gcctgcccac acaagggcag tgaagaaggc gaaagttgac   3300 

gccgccaaga acaaggaccc ggggtacgat cgcacgcaag aggagcttga cgcttacgtt   3360 

gcatcagaag tcaagagaca attcaagcct cgaagtccag aaaagaagat tcctatagac   3420 

cccagtgtca ggaacttctt caggggtatg tctgcatctg tcaaggaggc catcaagcta   3480 

tcggactatg agcgaacgct gaagaaagca tcttctggaa agtccaaacc agtccctcag   3540 

cttggagagc aaccaaacca ggagatcgag ccgttggtga ccagtaaaga aatgacgata   3600 

gaacaattta ttactgacac cggtctaact acggatcaat tgctaggagt cgcaccaatc   3660 

gaaaaggcga aagtgaaata catgtacgaa ctcggtaaac cgcttgtcaa gcctgagctg   3720 

ctgcagtccc tacccacaca aatgtacaag ttccatcagc tgtacatgga gatgagcgcc   3780 

accggtagag agatgatcgg agcgacgatc agggacacgg acttcttgca aggagatgac   3840 

attctctgga tcaatttcag gggaatctac gaactatacc agctggacgc cctcgacgtc   3900 

tctattatga gttgctggat tttgtaagta tatcgttcaa ttataattct taattactac   3960 

gtctccttta attaattagg tccttgtata taagtagact atataaaata aaatactccc   4020 

ttttatcgtt gtagaatgga gattcaaagg gcccgacggc ggagggtttt cgatactgga   4080 

ttcatcgacc ctcggagagt aaacgttgca atgctcgacc aatatccgca ggaaacagag   4140 

gacaatctcg tccatctcct gaaggcgcag cattacaaga cgttcatact gttaccgtac   4200 

aacacagagt tagtttaatt ttactgtctt cctacatacc aaatttcatt cccgtacgaa   4260 

cttgctaagt gtttcatatg taatgcatcc cacgcacatt gcagattcca ctgggtgctt   4320 

ttactcttcg acctggaggc ctgcaccgtc aacgtatatg actcaatgga taaaaaagag   4380 

tctacgtttg acaaggtttt cgaacttata gacaggtacc gtcataagtt cctttgttaa   4440 

ttaagaaaat cttgttatgt taattgctac tacgaatcat agctttaaac tccatgtagg   4500 

gcttggtatc ggttccgtca tttggtccgc agcaaatgga gagaaagact taggcggaag   4560 

ttcaaatttc ctgtgagtac acatgctcta catttatatt tctccgattc aaattaatac   4620 

atacaactgt atattaatta gatctcacgc cgttaatttg tcatttattt gtagtgcgca   4680 

aagcaaaagc agggaactaa cttgtgcggc tactacgtgt gtgagtattg ccactgcctt   4740 

acagaccaaa tcatcaccac aagagagctc gatgtacgta caaataaatt caaaatttca   4800 

ttacgtaacg atttcttgtt taattactaa tcaatttcat acattcatat agtttattcg   4860 

catgagggat aacctgacca cacacaagga atttatcgca gcggttcaag aacaactcat   4920 

gggattcatc aacgaagata tccttgatcc caagggtgaa ttctactacg acggaaacac   4980 

aattcaccgg tccttagctt ctgagctagc agcgactact actacgtcga aatcgtagct   5040 

agctaggaca taaaatggat tgtaattaat atatgactac atatgtttct atatgcatgt   5100 

gtacacattt tctataatgt aaatatattt tggtcatata tatatctata tacatatgca   5160 

tttgcataac atatatatgt ataaatacat atatattatg catgtatata catataatat   5220 

aatatatata tatatataca tatatatatg tatgcatata tatgtattga aacatatata   5280 

tgcatggttt ttatatatat atatatatat atatatatat atatatatat atatatatat   5340 

atatatmtat ataaaccatg cagcaacagg gccatgcaaa aaaaaaaggt cagctcgatc   5400 

tttagtcccg gttatttcac ccgggactaa agatagcgat ctttagtccc ggattggtac   5460 

tcccggtttg gaaaccggga ctaaaggggg ttacgaaccg ggactacaaa gggtttctcc   5520 

actagtgtat taatttcata ttagttacac tacaattaca ctgtagttac attcgtaagt   5580 

acagtataac tagggtgtaa tttttttaaa agaaagattc tggtgtagtt acactataat   5640 

tacactatag ttacattcgt aagtacagta taattagggt gtaatttttt taaaagaaag   5700 

attttggtgt agttacacta taattacact atagttacaa gtgtaagtat agtgtaacta   5760 

gggtgtaatt ttttaaaaaa actttttagt gtagttacac tataattata tattagttac   5820 

acagtactta catattagtt atactataat tacactatag ttacaaatgt aagtatagtg   5880 

taattagggt gtaatttttt ttaaaaaaag cctttagtat atgtgctgac aagtagttag   5940 

ttttgtggct tggattaaca cgccttaatc tacactatag gcgttgcttt ttaatttggc   6000 

tagcaagttg gccgtttggt ggttagaaaa atctgtgtga tttataacaa aaatctgtcg   6060 

ggtgttatat agatagatct tcaaaatttg gcagtaaact aaatgtagcc acttttttga   6120 

caactttacc aaaatttggt aagattaaaa atggcatcaa agtgaacagg cccatagtat   6180 

atcgtatatt gttagggact attaaaaaac tgccctaagt tctttaagaa aaaaacttta   6240 

attatagtat aattgtaata tgattccact ataactatta tataactttt atataagtat   6300 

taaaataata tatacagttt tatatctaac ttatatagat attacaatat acttacagtg   6360 

cagatacaat gtaactatat agttacagcg taatttacaa tgtaactata ctgtaattac   6420 

attatactgt aattacatta tagttaaact tgcgacagtt tttttagcaa tttcgtatat   6480 

atagcatgaa atcgccatgg tttaaaacct atctattatt agtaccccca ttatttaatt   6540 

atatgttgtt tttacttttt ttaatcaaat ttttttagat ttaatcaagt ttatagaaaa   6600 

ttttagtaac atgtataaaa ccaaattagt ttcatcagat gaaagattta atagattttg   6660 

ataatatata tattttgtgt tgaaaatgct actatatttt tctataaatt tggttaaact   6720 

ttaaaaaagt tttattagga aaaaaatcaa aatgacttat aatatgaaac tgatggagta   6780 

gaaaaaaggg gcaggcctca aatcctgcaa tccaaagaat aaa                     6823