Patent Publication Number: US-11395891-B2

Title: Methods and delivery devices using herbal extracts

Description:
CLAIM OF PRIORITY 
     This application is a continuation of U.S. patent application Ser. No. 15/199,366, filed Jun. 30, 2016, which application is a continuation-in-part to U.S. patent application Ser. No. 14/574,591, filed on Dec. 18, 2014, now issued as U.S. Pat. No. 9,380,813, which is a continuation-in-part to U.S. patent application Ser. No. 14/264,999, filed Apr. 29, 2014, now issued as U.S. Pat. No. 9,220,294, which claims the benefit of priority to U.S. Provisional Application Ser. No. 61/938,577, filed Feb. 11, 2014. U.S. patent application Ser. No. 14/574,591 also claims the benefit of priority to U.S. Provisional Application Ser. No. 62/058,431, filed Oct. 1, 2014. U.S. patent application Ser. No. 15/199,366 is also a continuation-in-part of International Application Serial No. PCT/US2015/015445, filed Feb. 11, 2015 which is a continuation International Application Serial No. PCT/US2015/014418, filed Feb. 4, 2015, which is a continuation of U.S. patent application Ser. No. 14/574,591 filed Dec. 18, 2014, in which all aforementioned applications are hereby incorporated by reference herein in their entirety. 
    
    
     TECHNICAL FIELD 
     The present application relates to methods and devices using herbal extracts, and more particularly, to methods of purifying herbal extract(s) from herbaceous plants with naturopathic and/or medicinal properties to create delivery products containing herbal extracts useful for naturopathic and/or human beneficial purposes. 
     BACKGROUND 
     Herbal extracts, otherwise known as botanical medicines, are derived from naturally occurring herbaceous plants by extraction from the seeds, berries, stems, branches, leaves, bark, roots or flowers or other parts of the plants. Herbal extracts are well known for medicinal purposes dating back to ancient Chinese and Egyptian writings. Herbaceous plants also constitute a source for development of modern pharmaceutical medicines and herbal extract(s) ranging from the development in the late 1800&#39;s of aspirin, a derivative of the silver willow bark, to the development in the 1980&#39;s of paclitaxel, a terpene derivative of the yew bush. When used as medicinals, herbal extracts can provide numerous benefits and can be used, for example, to treat pain, cancer, muscle spasm, depression, viral and bacterial infection, nausea, cardiovascular problems, lung problems, joint and osteoporosis problems, blood clots and other physiological problems. 
     Herbal extracts traditionally are administered by oral, topical, inhalation and/or injection methods. Inhalation of vaporized herbal extracts is a common form of administration. However, the traditional methods do not control dose or timing of the delivery. Moreover, traditional methods do not utilize purified extracts so that the herbal extracts typically contain plant side products, carcinogenic substances and other deleterious plant substances. Furthermore, in some circumstances, the vapors of the medicinal herb plant material are inhaled by burning the plant material, in other words by smoking. The combustion of the plant material can also release many toxic substances such as ammonia and hydrogen cyanide that can cause tissue damage if ingested. Ingestion of foods laced with herbal extracts material can also deliver herbal extract(s) to the body. However, undesirable materials in the herbal extracts are also ingested and the dosages of the ingested herbal extract(s) can be inconsistent and hard to determine. 
     Isolation and purification of herbal extract(s) from herbaceous plants can be of great interest and benefit to the medical community. A way to purify herbal extract(s) from herbaceous plants and convert the purified forms into an easily-ingestible form and/or to administer such purified forms or derivatives thereof is desired. 
     GOALS OF THE INVENTION 
     There is an opportunity for an herbal extract(s) delivery product that allows for inhalation of herbal extract(s) without inhaling other undesirable components found in raw herbaceous plants or created by burning the raw plant material. The amount and purity of herbal extract(s) in the delivery product can be controlled for dosage. The delivery product can be formed using a separation and coating process, as described herein, that facilitates controlled deposition of herbal extract(s) onto a substrate to form the delivery product. 
     SUMMARY OF THE INVENTION 
     The present invention is directed to methods for purifying herbal extract(s) from herbaceous plant material; providing substrates containing or incorporating the purified herbal extract(s); and providing apparatuses for delivery of herbal extract(s) to patients and consumers. 
     In a first aspect of the invention, the method is directed to controlled volatilization or wet extraction of the herbal extract(s) from herbaceous plant material, that is preferably comminuted, and absorption, adsorption, deposition or otherwise combining the volatilized or extracted herbal extract(s) with a substrate. When an individual herbal extract is obtained by volatilization, the substrate is held at a temperature to assure capture of the volatilized herbal extract by its condensation on the substrate (preferably cooled). When an individual herbal extract is obtained by wet extraction, a concentrate of the herbal extract in solvent is deposited onto the substrate with evaporation to form a dried layer on the substrate. 
     A second aspect of the invention is directed to the substrate with deposited herbal extracts. The substrate with herbal extract(s) is constructed and configured to enable release of the herbal extract(s) upon controlled heating. This aspect can include controlled release of the herbal extract(s) so as to provide regulated, controlled, limited doses of herbal extract(s) over time. 
     In a third aspect of the invention, the substrate with deposited herbal extract(s) is converted into a delivery cartridge. The delivery cartridge can be used with a controllable heating element to volatilize or entrain as a vapor or aerosol the herbal extract(s) and inhale the vapor or aerosol. 
     A fourth aspect of the invention is directed to a delivery system which can include a delivery cartridge described above. In an example, the delivery cartridge can include a cylindrical structure extending in a longitudinal direction and formed from an electrically conductive material. The cylindrical structure can include multiple electrodes extending laterally across the substrate at respective longitudinal locations. Each of the electrodes has an electrical resistance small enough to conduct current laterally along the substrate without heating the cylindrical structure. The cylindrical structure can include at least one substrate portion extending longitudinally between a respective pair of electrodes. Each substrate portion can have an electrical resistance high enough to conduct current longitudinally between the electrodes and resistively heat the respective substrate portion in response to the current conducted there through. A dose of an herbal extract(s) can be disposed on each substrate portion and configured to volatilize into a gas or vapor or entrain into an aerosol in response to the resistive heating of the respective substrate portion. 
     A fifth aspect of the invention is directed to the configuration and construction of the herbal extract(s) on the substrate. If multiple extracts are present, they may be arranged as overlapping layers or as segregated layers on the substrate. If the layers are overlapping, they may be arranged in any order and preferably are arranged with the herbal extract having the lowest volatilization or entrainment temperature as the top layer and the herbal extract having the highest volatilization or entrainment temperature being the bottom layer next to the substrate. With the overlapping arrangement, volatilization or entrainment is accomplished by controlling the temperature in increasing stages. With the segregated arrangement, volatilization or entrainment is accomplished by a series of heating elements, each of which is controlled to produce the appropriate volatilization or entrainment temperature for the corresponding herbal extract of the segment. 
     A sixth aspect is directed to an apparatus and method for producing herbal extract(s) from the raw herbaceous plant material and depositing the herbal extract(s) on the substrate. The apparatus includes a component for comminution of the herbaceous plant material, a component for controlled heating of the comminuted plant material to volatilize the herbal extract, and a cooled substrate on which the volatilized herbal extract is condensed and deposited. 
     A supplement of this aspect includes a cooled transport belt in place of the substrate. The volatilized herbal extract is condensed and deposited on the transport belt. A knife scraper or other remover apparatus is positioned to remove the herbal extract from the belt which is preferably heated so as to place the herbal extract to a liquid state. A transport mechanism, preferably heated, deposits the herbal extract appropriately on the substrate at a relatively close location. The appropriate deposit of the herbal extract is preferably controlled so as to deposit a unit dose of the herbal extract on the substrate, the apparatus being capable of continuously preparing substrate pieces with purified extract having the dimensions suitable for use in the delivery system. 
     A seventh aspect is directed to a method for wet extraction of the herbal extract(s) from the herbaceous plant material. The herbaceous plant material is comminuted to provide very small particles and the particles optionally dried in air to remove water within the plant material. The dried particles are combined with a solvent in which the herbal extract is soluble and agitated or otherwise mixed to extract into the solvent the herbal extract and produce a solution. The solution is filtered, optionally treated with activated charcoal and optionally chromatographed or fractionally distilled or optionally crystallized to further purify the herbal extract. Either following the optional purification steps or without use of these steps, the herbal extract in solvent is concentrated to produce a concentrate. The concentrate may be deposited with evaporation on the substrate to form a dried layer or coating of herbal extract on the substrate. Optionally the concentrate may be treated with a non-solvent for the herbal extract to crystallize the herbal extract or “oil out” the herbal extract as an amorphous solid. The solid may be filtered, dried and may be directly deposited or otherwise cast on the substrate. The substrate with solid may be optionally heated to liquefy or otherwise convert the solid into a contiguous layer of herbal extract on the substrate. The so-coated substrate is used as described above to form a delivery cartridge and subsequently a delivery system. 
     This Summary is intended to provide an overview of subject matter of the present patent application. It is not intended to provide an exclusive or exhaustive explanation of the invention. The Detailed Description is included to provide further information about the present patent application. 
    
    
     
       BRIEF DESCRIPTION OF THE DRAWINGS 
       In the drawings, which are not necessarily drawn to scale, like numerals may describe similar components in different views. Like numerals having different letter suffixes may represent different instances of similar components. The drawings illustrate generally, by way of example, but not by way of limitation, various embodiments discussed in the present document. 
         FIG. 1A  is a side view of an example of a single herbal extract coated substrate in accordance with the present invention. 
         FIG. 1B  is a top view of a substrate coated with herbal extract(s) of  FIG. 1A . 
         FIG. 1C  is a side view of an example of a multilayer herbal extract coating on a substrate in accordance with the present invention. 
         FIG. 1D  is a side view of an example of a substrate with a segregated multi-coating herbal extract. 
         FIG. 2  is a block diagram of an example of a process for making a delivery cartridge in accordance with the present invention. 
         FIG. 3  is an example of a heating chamber having a batch substrate coating process for creating a coated substrate in accordance with the present invention. 
         FIG. 4  is an example of a heating chamber having a continuous substrate coating process in accordance with the present invention. 
         FIGS. 5A, 5B and 5C  are examples of a series of heating chambers for producing a multi-layered substrate coating process in accordance with the present invention. 
         FIG. 5D  is an example of a substrate with multiple layers of herbal extract(s) 
         FIGS. 6A and 6B  present an example of a heating chamber with transfer cooling belt, knife scraper and substrate deposit; and a storage and deposit system for processing one of more batches of herbaceous plant material in accordance with the present invention. 
         FIG. 7A  is an example of a penultimate form of a delivery cartridge formed of a substrate with a multilayer coating of herbal extracts and separation spacers in accordance with the present invention. 
         FIG. 7B  is an example of a penultimate form of a delivery cartridge with a segregated multi segment substrate in accordance with the present invention. 
         FIG. 7C  is an example of an end view of the delivery cartridge formed from the penultimate cartridge form of  FIG. 7A . 
         FIG. 8  is a block diagram of an example of a process to construct a delivery cartridge having a spirally wound cylindrical shape, in accordance with the present invention. 
         FIG. 9  is an example of a delivery cartridge in accordance with the present invention. 
         FIG. 10  is an example of a delivery cartridge having multiple overlapping layers of coated substrates, in accordance with the present invention. 
         FIG. 11  is an example of a delivery cartridge having multiple segregated layers of coated substrates, in accordance with the present invention. 
         FIG. 12  is a block diagram of an example of a process to construct a delivery cartridge in accordance with the present invention. 
         FIG. 13A  is a top view of an example of a polygonal delivery cartridge in accordance with the present invention. 
         FIG. 13B  is a perspective view of the polygonal delivery cartridge of  FIG. 13A . 
         FIG. 13C  is a side view of the coated substrate of the delivery cartridge of  FIGS. 13A and 13B  prior to forming the polygonal shape. 
         FIG. 13D  is an end view of the coated substrate of  FIG. 13C  formed into a polygonal shape. 
         FIG. 14  is a block diagram of an example of a process to construct a polygonal delivery cartridge in accordance with the present invention. 
         FIG. 15  is an exploded cross-section view of an example of a multi-layer substrate in accordance with the present invention. 
         FIG. 16  is a block diagram of an example of a process used to make a delivery cartridge having two or more layers, in accordance with the present invention. 
         FIG. 17  is a perspective view of an example of a delivery cartridge in combination with a delivery device, in accordance with the present invention. 
         FIG. 18  shows an example of a cylindrically rolled sheet, which can be suitable for use with a delivery system. 
         FIG. 19  shows a cross-section of the rolled sheet of  FIG. 18 . 
         FIG. 20  shows the cross-section of the rolled sheet from  FIG. 19 , with the addition of an optional plurality of electrically insulating spacers positioned to space apart adjacent rolls of the rolled sheet. 
         FIG. 21  shows another example of a cylindrically rolled sheet. 
         FIGS. 22 and 23  show examples of a delivery system with control circuit for providing multi-temperature staged heating of coated substrate. 
         FIG. 24  is a side-view schematic drawing of another example of an herbal extract(s) delivery system. 
         FIG. 25  is a schematic drawing of an example of an interface connector for use with a vaporizer nebulizer and controller. 
         FIGS. 26A and 26B  are schematic drawings of a wet extraction process and device and remote multi-storage and deposit unit. 
     
    
    
     DEFINITIONS 
     The following terms as used herein according to the invention have the following meanings. 
     The terms “herbs” and “herbaceous plants” in the singular and plural are understood to mean all kinds of plants, funguses and algae that can contain or can produce substances that have a pharmacological, physiological, beneficial, sensory or other perceived or un-noticed but measurable effect on humans. The term herbaceous plant includes the stems, seeds, buds, roots, leaves, branches, bark, flowers fruit and all other parts of a plant. Preferably, these parts may be selected to provide only the plant part containing the desired herbal extract if appropriate. The term “herbaceous plant material” is understood to mean comminuted herbaceous plant material unless in context this term describes a whole plant. 
     As used herein pursuant to the invention, an “herbal extract” and/or “extract” are understood to mean a substance or derivative thereof obtained directly from an herbaceous plant or indirectly through synthetic methods applied to such plants and/or substances. An herbal extract can be a solid, oil or liquid and can have a pharmacological, physiological, beneficial, sensory or other perceived or unnoticed but measurable effect on humans (e.g., an unnoticed but measurable effect may be, but is not limited to, lowering of blood pressure). In addition to the popular understanding that an herbal extract is a flavor, taste and odiferous substance for use in foods, the term herbal extract(s) and related terms used herein include medicinal agents and substances, pharmacological agents and substances, and chemical agent, substances and compounds known or derived from any kind of plant, fungus or algae. Included also are semi-synthetic derivatives of such substances. The term “herbal extract(s)” includes any of the phrases “one or more herbal extracts” an “herbal extract or extracts”, and herbal extract, in other words, the singular herbal extract and the plural herbal extracts, i.e., multiple herbal extracts 
     As used herein according to the invention, the terms “volatilize” and/or “volatilization” are understood to mean vaporization of an herbal extract from an herbaceous plant, which is either a liquid or a solid and is vaporized to a gas or vapor phase. In an example, one or more herbal extracts described herein may start as a solid or an oil and be heated such that the one or more herbal extracts vaporize. The one or more herbal extracts may transition directly from the solid to the gas phase, a sublimation process, or the one or more herbal extracts may become a liquid and then vaporize to a gas. In an example, the one or more herbal extracts described herein may be in a liquid or solid form prior to heating. 
     As used herein according to the invention, the terms “entrain”, “entraining” and/or “entrainment” are understood to mean formation of a solid-gas mixture such as a solid-gas aerosol with air in which a solid, oil or liquid herbal extract is heated to an extent that it forms microparticles or micro-droplets of liquid dispersed and/or mixed in a gas such as air. The common form of such a dispersion is a particulate-gas aerosol or a liquid droplet-gas aerosol. The entrainment does not require the herbal extract to vaporize into a gaseous state but instead to form an aerosol. 
     DETAILED DESCRIPTION 
     The present application relates to methods of purifying the herbal extract(s) from herbaceous plant material by heating the herbaceous plant material to vaporize the herbal extract(s) and condensing the vapor onto a substrate to form a substrate coated with herbal extract(s). Alternatively, the herbaceous plant material can be wet extracted with an appropriate solvent to produce solution of herbal extract in solvent. The solution can be concentrated to produce a concentrate and the concentrate can be deposited on a substrate and dried to produce a substrate coated with herbal extract. With either technique, multiple overlapping or segregated layers of one or more herbal extracts can be deposited on the substrate. 
     The coated substrates can be converted into various three-dimensional structures configured for use as a delivery cartridge. The delivery cartridge can be heated and air or inert gas can be passed through the cartridge, thus volatilizing as a vapor or entraining as an aerosol the herbal extract(s) in the delivery cartridge such that the user can inhale the herbal extract(s) for a medicinal effect and/or therapeutic effect and/or beneficial effect. The purity and ratios of herbal extract(s) in the delivery cartridge can be controlled based on the desired composition, and the quantities of herbal extract(s) can be controlled based on the desired dosage. Based on the processes used to form the coated substrates, undesirable components in the herbaceous plant material are not included in the delivery cartridge. The delivery cartridges described herein can be used with various types of delivery devices to aid in inhalation of the herbal extract(s) 
     The delivery cartridge can be a cylindrical structure extending in a longitudinal direction and formed from a substrate of an electrically conductive material. Electrodes can extend laterally across the substrate at respective longitudinal locations. The electrodes can each have an electrical resistance small enough to conduct current laterally along the substrate without heating the cylindrical structure. One or more substrate portions can have an electrical resistance sufficient to conduct current longitudinally between the electrodes and resistively heat the substrate portions. Herbal extract(s) can be disposed on the substrate portions and configured to volatilize or aerosolize or entrain in response to the resistive heating of the substrate portions. The cylindrical structure or other type of delivery cartridge can be used in various types of delivery systems. 
     With reference to the figures, details of examples and aspects of embodiments of the invention are described. The descriptions of the examples and aspects do not limit the scope of the invention. 
       FIGS. 1A and 1B  show side and top views of an example of a coated substrate  100  of the present disclosure. The coated substrate  100  can include a substrate component  110  onto which an herbal extract(s) component  120  can be deposited. The coated substrate  100  can be exposed to heated air  130 , and the herbal extract(s) component  120  can be volatilized and/or entrained in the heated air  130  to form a vapor, an aerosol or a gas-particulate mixture in which the herbal extract(s)  140  is present. The vapor or aerosol  140  can then be ingested by a user to induce a medicinal or therapeutic effect on the user. 
       FIGS. 1C and 1D  respectively show the side views of an example of a substrate with a multi-layer overlapping herbal extract coating and an example of a substrate with a multi-layer segregated multi-layer herbal extract coating. Substrate  110  is coated with overlapping layers ( 120 A, B and C) or segregated layers ( 120 D, E, F and G) respectively. The layers can be exposed to air heated in stages to increase the air temperature or can be electrically heated in stages to raise the temperature of the layers and volatilize or entrain simultaneously or sequentially the multiple herbal extracts. 
     The substrate component  110  can be constructed from any naturally-occurring material or any man-made material, such as an FDA-approved polymer for the delivery of one or more herbal extracts, or any combination of naturally-occurring and/or man-made materials. The material selected for the substrate component  110  is inert at the heating temperatures described below for forming the coating on the substrate and the heating temperatures for later imbibing, inhaling, ingesting or otherwise administering the one or more herbal extract(s) components from the coated substrate. In an example, the substrate component  110 , can include, but is not limited to, materials where the substrate component  110  can be elastic, flexible, resilient, permanently deformable or plastically deformable. 
     For examples including resistive heating of the substrate, the substrate may be electrically conductive such as a metal including aluminum or an electrically conductive organic polymer such as high temperature polyethylene, polypropylene or polycarbonate or polyacrylate or similar polymers preferably doped to make the polymer(s) electrically conductive, as well as inorganic (e.g. silicone) polymers. The resistive potential of the substrate will be sufficient to generate heat and volatilize or cause entrainment of the herbal extract(s). 
     In an example, the substrate component  110  can assume the form of any three dimensional structure, including, but not limited to, a sheet, a mesh, or any combination of three dimensional structures. Other types of structures can be employed without departing from the present subject matter of the invention. In an example, the substrate component  110  can be a sheet of polymer material. In an example, the substrate component  110  can be a sheet of aluminum mesh, a sheet of solid aluminum or a combination of both aluminum mesh and aluminum sheet. As used herein, the term aluminum can include all grades of aluminum and aluminum alloys. Materials suitable for use as the substrate component  110  are also described below in reference to  FIG. 3 . 
     As described further below, the substrate component  110  can be formed into a variety of three-dimensional shapes to form a deliver cartridge with herbal extract(s). In an example, the delivery cartridge can be designed to maximize the surface area of the herbal extract(s) component  120  exposed to the flow of heated air  130 . In an example, the substrate component  110  can be shaped into forms including, but not limited to, a cone, a tube or tubular structure. As used here, a tubular structure can include any structure with an open cross-sectional area shape, a closed cross-sectional area shape, or a combination of open and closed cross-sectional area shapes. In an example, the cross-sectional area shapes can include, but are not limited to, circles, ovals, ellipses, squares, rectangles or other polygonal shapes. In an example, the cross-sectional area shapes can be open or closed shapes. Other types of structures can be employed without departing from the present subject matter. 
     The herbal extract(s) component  120  can include any substance or agent having a pharmaceutical, physiological, medical, beneficial, sensory, perceived or unperceived but measurable effect upon a human. The substance or agent may be present in an herbaceous plant material or in a semi-synthetic derivative of plant material. In an example, the herbal extract component  120  can include one or more active components for medicinal purposes, physiological action or therapeutic effect. In an example, the herbal extract component  120  can include one or more extracts found in herbaceous plant material, including one or more of the plant materials such as herbal extracts of herbaceous plants. As discussed above, herbaceous plants in the context of the invention include spice and flavor producing plants, flowering plants, trees, bushes fungus, algae, medicinal agent plants, alkaloid producing plants, complex hydrocarbon producing plants and any kind of plant that has been found to contain or produce an organic compound that has a pharmacological, physiological, beneficial, naturopathic, sensory or other desired effect on a human. The herbal extracts may be polycyclic hydrocarbons, heterocycle compounds, saturated and unsaturated poly-hydrocarbon acids and esters, purines, pyrimidines, alkaloids, terpenes, steroidal compounds such as budesonide, mometasone or fluticasone, macrocycles, anti-infectives, naturally occurring esters, naturally occurring acids, naturally occurring amines, naturally occurring amides, naturally occurring Schiff bases and combinations and semi-synthetic derivatives thereof. These extracts may exhibit such therapeutic or physiologic effects as bronchodilator, cardiovascular, antibacterial, anti-infective, anti-viral, mucolytic, psychological, endocrine, gastrointestinal, digestive, anti-asthmatic, cardiopulmonary, renal, urogenital, reproductive, anti-conceptive, central nervous system, sympathetic and parasympathetic nervous system effects, skin, cranial-sinus, and other pharmacological effects. These therapeutic, pharmacological and/or physiologic effects are known attributes of the herbal extracts. Administration of herbal extracts that are controlled substances such as opiates and/or have significant pharmacological and/or physiological effects should be accomplished only under the guidance and wisdom of a registered M.D. or D.O. physician, nurse practitioner or physician&#39;s assistant who is qualified and licensed to prescribe such substances. In addition, purchase and use of such controlled substances made pursuant to aspects of this invention should only be made under the supervision and licensure of qualified pharmacists. 
     As an example, the herbaceous plants may be selected from the group consisting of damiana, blue lotus, mullein, lobelia, peppermint, spearmint, catnip, thyme, sage, wild dagga, lavender, rosemary,  Salvia divinorum , basil, lemon balm, hops, yerba mate,  Calea zacatechichi , chamomile, ashwagandha  eucalyptus , passion flower, St John&#39;s wart,  valerian, astragalus, Avena sativa , kinnikinnick, cacao, chago, cinnamon, nutmeg, mace, cordyceps, Don Quai, Gotu  Kola , ginger root,  ginseng , green tea,  kava, maca , moringa leaf, mullein, sacred pink lotus, red raspberry,  rhodiola, rooibos , tong kat ali, vanilla, yohimbine, garlic, turmeric, nutmeg, capsaicin, rosemary,  cannabis , coniferous trees, yew bush, willow tree, aspen tree, blood root, opium poppy,  Atropa belladonna , strychnine,  Vinca rosea , coffee plant, cacao tree and beans (chocolate), coca plant (cocaine), nicotinaa  tabacum, Camelia sinensis , monkshood, castor oil, henbane, calabar bean,  digitalis  sp, autumn  crocus , peyote,  amanita , orange, lemon, and similar known herbaceous plants in which useful herbal extracts are known to be present. Some of these herbal extracts can be obtained commercially as they have previously been extracted for the herbaceous plant materials. Still others have been synthetically derivatized to form semi-synthetic compounds. The most useful forms of such herbal extracts and semi-synthetic compounds are the free base or free acid forms or neutral, uncomplexed forms. These forms lend themselves to volatilization and/or molecular entrainment as vapors and/or aerosols. The salt forms of bases and acids as well as complexed forms of neutral compounds can preferably be converted into the non-salt and/or non-complexed forms for use according to the invention. 
     The extracts of herbal plant material can exist in several parts of the plant including, but not limited to, leaves, stem, roots, branches, bark, flower, flower buds and/or fruit or seeds. In an example, the herbaceous plant material can include components such as all of the foregoing parts of a plant. As used herein, herbaceous plants can refer to plant material that has been harvested but is otherwise unprocessed. In an example, the plant material such as leaves, stems, bark, branches, seeds, roots, flowers and/or fruit can be shredded, chopped or otherwise comminuted to increase the surface area of the material in preparation for purification. In an example, the desired herbaceous material can include small particles produced by comminution. In an example, the herbal extract can be obtained by solvent extraction treatments or volatilization treatments or fractional distillation treatments of the comminuted herbaceous material. 
     Multiple references are made herein to a starting material of herbaceous plant material. It is recognized that any herbaceous plant composition can alternatively be used in the descriptions and examples below. Some of the processing steps, such as the separation or purification step, may vary depending on whether herbaceous plant material or an alternative form of an herbal plant material composition is used. 
       FIG. 2  shows an example of a process  200  that can be used to form a delivery product containing herbal extract(s), also referred to herein as a delivery cartridge. In an example, the delivery product includes herbal extract(s). In the process  200 , a pre-processing step  210  can include receiving source material, such as, for example, raw herbaceous plant material. In an example, the pre-processing step  210  can include collection of raw herbaceous material from growers for use as source material and removal of undesirable organic and inorganic components from the source material. In an example, the source material can be a whole plant as discussed above or appropriate parts of the plant known to contain the desired herbal extract(s). 
     A first inspection step  220  can include examination of the source material for general suitability in the process  200 . In an example, source material that is diseased or not otherwise of a specified quality can be removed from the source material before further processing. 
     A source material preparation step  230  can further prepare the source material for later steps in the process  200 . In an example, the source material preparation step  230  can include the use of equipment and methods to increase the surface area of the source material, such as by shredding, chopping or otherwise comminuting, to aid in a purification process. 
     A second inspection step  240  can include examination of source material to ensure that the source material has been suitably processed. In an example, source material that has been improperly shredded or chopped may be rejected or redirected for further processing. 
     A purification and coating step  250  can include a process for separating the herbal extracts component  120  of  FIG. 1  from the herbaceous plants. The purification in step  250  can include heating the pre-processed plant material to volatilize the herbal extract(s). Specific steps can depend on the form of the herbaceous plant material. Under step  250 , the volatilized herbal extract(s) can then be condensed onto a carrier material to form a substrate coated with the herbal extract(s). In an example, the condensation of volatilized herbal extract(s) on a carrier material such as a substrate or on a cooled transport device can be accomplished through cooled absorption or cooled adsorption of the volatilized herbal extract. The purification and coating step can also be practiced multiple times or simultaneously practiced with multiple apparatuses to produce multiple herbal extracts deposited as overlapping layers or segregated layers on the substrate. 
     Alternatively, the purification and coating step  250  can include an extractive process for separating the herbal extract from the herbaceous plants. The appropriate plant material, e.g., the whole plant or selected plant parts such as flowers, seeds, buds, leaves, stems, branches, bark and/or roots, may be comminuted into very small particles. The small plant particles may be extracted with a solvent in which the desired herb extract is soluble to form an extract solution. In some examples, the solvent may be water while in others it may be ethyl alcohol, chloroform, supercritical carbon dioxide or a hydrocarbon. The extract solution may be decolorized with activated charcoal and/or further purified by column chromatography on diatomaceous earth or silica gel or other suitable known chromatographic support material, for example. The purified extract solution may be concentrated by substantial but not complete evaporation of the solvent to form a concentrate. The concentrate may be parsed onto the substrate and the remaining solvent evaporated to deposit the purified herbal extract on the substrate. Also, if the herbal extract is commercially available, it may be purchased in purified form and formulated in a minimum amount of appropriate solvent to form a concentrate as discussed above. The subsequent steps to form the purified herbal extract on the substrate may be carried out as described above. If multiple overlain layers of herbal extract are to be formed, subsequent layers may be deposited on top of previous layers by flash evaporation. As the subsequent concentrate is laid down over a previous layer, a flow of air or inert gas at a temperature to instantly evaporate the solvent is applied. The result is deposition of dry herbal extract and avoidance of comingling of the various layers that might result from solvent dissolution. 
     A third inspection step  260  can include examination of substrate coated with the herbal extract(s) for coating uniformity or other predetermined parameters. 
     A first post-processing step  270  can include identification and handling of the substrate coated with one or more herbal extracts. In an example, the coated substrate with herbal extract(s) can be marked or labeled for quality assurance and material handling purposes, such as delivery to inventory of the substrate coated with one or more herbal extracts. In an example, steps  260  and  270  can be skipped and the coated substrate from step  250  can go directly to step  280  for converting. 
     A conversion step  280  can include transforming the coated substrate with herbal extract(s) into forms convenient for consumption by an individual user. In an example, the conversion step  280  can include converting the substrate coated with herbal extract(s) into segments and forming the segments into delivery products or cartridges. In an example, the cartridge is constructed to maximize the volatilization or entrainment surface area of the coated substrate while minimizing packaging volume of the cartridge. In an example, the cartridge can be of a generally tubular form and assume any cross-sectional shape without altering the effect of the cartridge. In an example, the cross-section shape can include, but is not limited to, a circle, a square, a hexagon, a polygon or any symmetric or non-symmetric cross-sectional profile. Other types of shapes can be employed without departing from the present subject matter. 
     A fourth inspection step  285  can include examination of the cartridges to ensure that the cartridges have been suitably processed. In an example, the fourth inspection step  285  can include examination of the user shapes for visual uniformity or other parameters. 
     A second post-processing step  290  can include packaging and labeling of the cartridges. In an example, each cartridge can be wrapped as an individual unit. In an example, individual units can be labeled for quality assurance and governmental tax purposes. 
     In an example, all the aforementioned steps of the process  200  can be subject to standard manufacturing control techniques. 
       FIG. 3  shows an example of a heating chamber  300  of the present disclosure for use in a single sheet substrate coating process when the herbal extract can be volatilized from the herbaceous plant material. The heating chamber  300  can include a container box  310  and a container cover  320  that can be removably attached to the container box  310 . The container box  310  can include an interior surface  312 , an exterior surface  314  and a controlled heat source  316  located along an interior surface  312  of the container box  310 . A removable tray  330  to contain a source material (plant material)  332  can be located against an interior surface  312  of the container box  310 . A removable screen  318  can be located in the container box  310  between the removable tray  330  and the container cover  320  to contain source material  332 . 
     The container cover  320  can include a hinge  326  to attach the container cover  320  to the container box  310  and a cooling bar  322  to which a substrate  324  can be located in close proximity or removably attached. In an example, the substrate  324  can be removably attached to the cooling bar  322  with clips or similar attachment aids. 
     The substrate  324  can be covered with a coating  328  of herbal extract(s) using, for example, a heating process. In an example, herbal extract(s) can be deposited on the substrate by sequential processing of the appropriate herbaceous plant materials. The depositions may overlay the respective multiple extract layers on top of each other or may segregate the layers on the substrate. The controlled heat source  316  can be initiated to heat the source material  332  to a selected temperature. Depending on the selected temperature, herbal extract(s) can volatilize from the source material  332 . The substrate  324  can be cooled through conduction (when in contact with the cooling bar  322 ) or radiation (when located in close proximity to the cooling bar  322 ) and the vapors generated during the heating process can condense onto the substrate  324  to form a coating  328  on the substrate  324 . In an example, the herbal extract(s) can be absorbed and/or adsorbed within and/or on the substrate  324 . In an example, the herbal extract(s) can be adsorbed onto the surface of the substrate  324  so as to produce a substrate coated with herbal extract(s). As used herein, a coated substrate  334  can refer to a combination of the substrate  324  and the coating  328  formed thereon. 
     In an example, the heating chamber  300  can be used to volatilize herbal extract(s) in the herbaceous plant material. Using the steps above, the desirable components, i.e., one or more herbal extracts, can be sequentially extracted and purified from the herbaceous plant material by controlling the temperature in the heating chamber and sequentially adding appropriate herbaceous plant material containing the desired herbal extracts. As described further below, various one or more substrates coated with herbal extracts can be formed that have one or more herbal extracts, in purified form, and contain minimal to no undesirable components. 
     The volatilization of the herbal extract in the heating chamber  300  can be based on the known volatilization temperature of particular herbal extract desired. Depending on a temperature that the herbaceous plant material is heated to, herbal extract(s) can be volatilized if more than one is present in the composition. Typically, the temperature of the heating chamber may approach the known volatilization temperature of the desired herbal extract. However, maintaining a slightly, to somewhat, lower chamber temperature can be utilized to assure primary production of the desired herbal extract in substantially purified form. Use of the partial vapor pressure of the herbal extract at a temperature below its volatilization temperature can be practiced to assure at least in part the production of substantially purified herbal extract. 
     Care is practiced to avoid combustion of the cellulosic and other materials of the herbaceous plant composition. While not a required condition for volatilization and deposition, applying a vacuum to the heating chamber can facilitate volatilization of the herbal extract at lower temperatures while not also producing undesirable substances or causing combustion. Preferably, the heating with or without partial vacuum is conducted under an inert atmosphere, such as a nitrogen or argon atmosphere. This aspect also is helpful for avoidance of plant combustion. 
     Water is almost always present in such plant material. Consequently, the herbaceous plant material can be pre-dried at ambient to slightly elevated temperatures to remove water. 
     In general, the temperatures at which each of herbal extract(s) can volatilize relative to their known volatilization temperatures in isolated, pure states are not necessarily precisely known and can depend, for example, on the surrounding conditions, the degree of comminution, the pre-drying removal of water and the particular plant part containing the herbal extract. The heating chambers described above can be used to heat the herbal extracts-containing composition to any given temperature. The particular temperature or temperature range selected can depend on multiple factors, including, for example, a particular composition of the raw herbal extracts or the desired composition of the coated substrate. Samples of the deposited or cooled vapors can be collected, at all or some of the temperature intervals, to analyze the fractions and determine the composition of the coating. Based on the results, the temperature range sufficient for volatilization can be determined or adjusted based on the desired composition of the coating. It is recognized that the temperature range can depend on the starting material and how tightly the composition of the coating is to be controlled. The composition of the starting material can vary from batch to batch and can depend, for example, on where and how the raw herbaceous plants are grown, and cleaning of the raw herbaceous plants or other preparation steps, prior to processing. 
     Practice and variation of these parameters are well within the ordinary and routine skill of a chemical technician to achieve the desired volatilization. The following discussion examines these parameters. 
     A composition of the coated substrate  334 , including a purity of the herbal extract(s) can be a function of the source material used in the heating process. In an example, the grade of herbaceous plant used as the source material, such as the species and source of supply, can influence the composition of the coated substrate  334 , including varying levels of one or more herbal extracts. In an example, the pre-processing of the source material, such as the size of particle resulting from shredding and chopping of the source material, can influence the composition of the coated substrate  334 . In an example, sampling can be performed on the source material to determine a composition of the source material. Specification parameters and standard processing control can be implemented for monitoring and controlling the composition of the source material and the coated substrate  334 . 
     The composition of the coated substrate  334  can be a function of the control parameters used in the heating process. In an example, the temperature and partial pressure (i.e., partial vacuum) of the chamber, the total time the source material is exposed to the temperature of the chamber and the temperature of the cooling bar  324  can influence the coated substrate  334 . In an example, these and other process parameters can be under standard processing control. 
     The substrate  324  can be constructed from any naturally-occurring material or any man-made material, such as an FDA-approved polymer for the delivery of one or more herbal extracts, or any combination of naturally-occurring or man-made materials. 
     The substrate  324  can be a pharmaceutically acceptable material or combination of materials, including natural and/or synthetic materials, which can capture the one or more herbal extracts. In an example, pharmaceutically acceptable materials for the substrate can include, but are not limited to, cellulosic materials, synthetically altered cellulosic materials, synthetic polymers, natural polymers or any material approved for pharmaceutical use by the United States Food and Drug Administration (FDA). In an example, the materials can be porous, micro-porous, adsorptive or absorptive or include a combination of adsorptive and absorptive properties. In an example, the substrate can be stable and non-degrading at temperatures well above the volatilization temperatures of one or more herbal extracts. In an example, the substrate  324  can comprise an aluminum or aluminum alloy. If a substrate is to be designed as an electrically conductive synthetic or natural organic or inorganic polymer, it will include a feature providing the ability to conduct electricity. Such electrically conductive polymers are well-known. 
       FIG. 4  shows an example of a heating chamber  400  of the present disclosure for use in a continuous sheet substrate coating process. The heating chamber  400  can include many of the same elements as the heating chamber  300  of  FIG. 3 , but instead of being a batch process, it can include additional features to enable a continuous process. The container cover  420  can include a roller take-up mechanism  424 . In an example, the roller take-up mechanism  424  can include a source spool mechanism  425 , a receiving spool mechanism  426  and a flexible substrate  427  extending from the source spool mechanism  425  to the receiving spool mechanism  426  and located in close proximity to the cooling bar  422 . In an example, the source spool mechanism  425  can include a spindle and bearings to support the source spool and a motor attached to the source spool for tensioning of the flexible substrate  427 . In an example, the receiving spool mechanism  426  can include a spindle and bearings to support the receiving spool and a motor attached to the receiving spool to draw the flexible substrate  427  across the cooling bar  422 . During the heating process, the receiving spool mechanism  426  can draw the flexible substrate  427  across the cooling bar  422  so that the herbal extract(s) condense on one side of the flexible substrate  427  to form a continuous coating  432  on the flexible substrate  427 . 
     In an example, the roller take-up mechanism  424  can be controlled to perform continuous deposition processing of the flexible substrate  427 . In an example, the roller take-up mechanism  424  can be controlled to perform multi-batch deposition processing of the flexible substrate  427 . Other designs can be used as an alternative to or in addition to the mechanisms  424  and  426  for enabling a continuous process. 
       FIGS. 5A, 5B and 5C  show an exemplary series of heating chambers  500 ,  501  and  502  of the present disclosure for use in preparation of a substrate with a multiple layer coating of different herbal extracts. The heating chambers  500 ,  501  and  502  can be separate chambers arranged in a tandem order or can be a single chamber which is replenished with different herbaceous materials as feed stocks and which serve to convert chamber  500  to chamber  501  and hence into chamber  502 . Heating chambers  500 ,  501  and  502  can include many of the same elements as the heating chambers  300  and  400  of  FIGS. 3 and 4 , respectively. When operated in tandem, the substrate  527  can be arranged on a continuous belt and roller as depicted in  FIG. 4 . The continuous belt and roller will extend through chambers  500 ,  501  and  502  with the outtake roller being positioned before chamber  500  and the uptake roller being positioned after chamber  502 . Alternatively, a single chamber  500  can be employed and the herbaceous plant material changed to provide an operational configuration of chambers  501  and  502 . In an example, flexible substrate  527  is coated in either a multi-batch or continuous deposition process with a first coat  531  of herbal extract from volatilization of herbaceous material  530  as shown in  FIG. 5A . The chamber  500  is refilled with herbaceous material  540  so as to provide chamber  501 . Alternatively, a second, separate chamber  501  is employed in this step as shown by  FIG. 5B . A second coating of herbal extract  541  is applied to the substrate with coating  531  by volatilization and cooling as depicted in  FIG. 5B . The result is a substrate with coatings  531  and  541 . In a third step as shown in  FIG. 5C  the original chamber is replenished with herbaceous material  550  so as to provide chamber  502 , or a third separate chamber  502  is used. Through volatilization and cooling, a third coating of herbal extract  551  is applied so as to produce a substrate with multiple coatings  531 ,  541  and  551 . The substrate coated with three herbaceous extracts  531 ,  541  and  551  is shown in  FIG. 5D . 
       FIG. 6A  shows an exemplary heating chamber  600  of the present disclosure for use in a continuous substrate coating process with a continuous source material feed system and a heated, remote storage and coating subsystem. The remote coating subsystem enables the use of a single heating chamber and a multiple number of storage and coating subsystems. The overall system enables large runs of herbaceous plant material and multiple coatings of batch substrates or continuous substrates. In an example, a screw conveyor  660  can move herbaceous plant material  634  into the feed hopper  610  for heating and volatilization. A screw conveyor  660  moves the herbaceous material  634  into the heating chamber  600 . The screw conveyer can also be used to remove spent herbaceous plant material from chamber  600  and dispose it into a waste hopper (not shown). Multiple feed hoppers can be connected to a single delivery chute leading to the screw conveyer. Each hopper can contain a different herbaceous plant material and the release of each into the screw conveyer can be controlled by hopper outlet valves. In this fashion multiple herbaceous materials can be delivered to the single heating chamber so as to produce multiple herbal extracts. Each volatilized herbal extract is collected on a continuous belt  641  cooled by cooling bar  640 . The belt with solidified herbal extract moves out of the heating chamber  600  and is subsequently warmed by heat source  642 . Stripper  643  or a similar device causes the warmed herbal extract to pass into storage hopper  650 . Storage hopper can be cooled or heated by heater/cooler  652  depending on whether the herbal extract is to be stored in hopper  650  or is to be transported through tube  651  to the remote coating subsystem  670 . As shown in  FIG. 6B , a remote series of coating subsystems  670   a ,  670   b  and  670   c  can be employed to provide substrates with multiple layers of herbal extracts or a series of substrates each with a single different herbal extract. The coating subsystem includes storage hoppers  650  with transport tubes  651  and heater coolers  652 . The system can be arranged on a rotating platform synchronized with the continuous belt  641  and stripper  643  so that a series of herbal extracts can be collected, stored and sequentially applied to a substrate. To form a substrate with one or more layers of herbal extract, storage hopper  650  is heated and the liquid herbal extract caused to flow through tube  651  to the remote coating subsystem  670 . The flowable herbal extract is deposited on substrate  671 , is leveled by a leveling means such as a knife edge or a curtain of air or by gravity optionally in combination with movement of substrate  671  . . . . The leveled herbal extract layer is cooled by direct or indirect contact with a cooler or by cold air. A deposition of subsequent layers of different herbal extracts contained in additional storage hoppers  650  can be accomplished by the same process to produce a multi-coated substrate. The same process and coating subsystem can be employed to produce and store multiple herbal extracts and coat substrates with single coatings of different herbal extracts. 
     In an example, any of the heating chambers described above can be part of a mobile process such that the purification and coating processes can be done at or near the origin of the source material. In an example in which the source material is raw herbaceous plant material, the purification and coating processes can be contained or stored within a transportation device such that these steps can be performed at or near where the raw herbal extracts is grown. 
     In an example, a batch process similar to the heating chamber  300  of  FIG. 3  can be used to sample source material and determine its composition, to determine, for example, levels of herbal extract(s) in the source material. 
     The heating chambers and processes described above in reference to  FIGS. 3-6  are an example of a separation process for separating one or more components from the herbaceous plant composition. Other known processes may be used, such as, for example, a wet extraction process or a fractional distillation process. The particular process used for separating the desired components from the source material can depend, in part, on the composition and form (solid, liquid, etc.) of the source material, the nature of the herbal extract(s) desired, the volume of coated substrate to be produced, the time for production, technical expertise of the users, equipment availability and budget, and the cost of implementation. 
     Alternatively, a wet extraction method can be used to obtain the herbal extract(s). In an example, an herbaceous plant material containing an herbal extract, such as but not limited to an alkaloid such as sanguinarine (blood root) or  digitalis  (digitalin and digitoxin from foxglove) can be comminuted to small particles and dried to remove water. Combining the dried herbaceous plant material with an appropriate solvent such as ethyl alcohol or chloroform or water extracts the herbal extract from the dried plant material and produces an herbal extract solution. 
     Optionally, treating the herbal extract solution with activated charcoal to decolorize, and optionally recrystallizing by addition of water followed by filtration, can be employed to produce purified herbal extract as an oil or solid. 
     Either the herbal extract solution can be concentrated by vacuum evaporation of a substantial amount of solvent to produce a concentrate or the purified herbal extract can be redissolved in a minimum amount solvent to produce a concentrate. The concentrate can be deposited as a layer of concentrate on a substrate. 
     The deposit can be accomplished by a batchwise technique involving placing the substrate in a catch pan with sides slightly higher than the side edges of the substrate. The catch pan and substrate can be sized to enable subsequent division of the coated substrate into dose calculated strips. The concentrate can be deposited onto the substrate in the catch pan that holds the concentrate at appropriate depth on top of the substrate. The concentrate can be flash evaporated by placing the catch pan with concentrate and substrate into a vacuum chamber and applying a vacuum with slightly elevated temperature. This technique will flash off the solvent while not volatilizing or subliming the herbal extract to any detectable degree. 
     The coated substrate can be cut or otherwise divided along predetermined lines to produce the unit dosage forms of substrate coated with herbal extract. As explained above, the coated substrate can be configured for use in a hot air delivery cartridge or configured with electric heating elements and flowing ambient air to entrain the herbal extract molecules in a micro-aerosol or solid particulate-gas mixture or volatize the molecules into a vapor for inhalation delivery to the lungs. 
     Administration of herbal extracts such as for example medicinal alkaloids such as sanguinarine (anti-bacterial) or  digitalis  (cardiovascular) and other medicinal herbal extracts by inhalation into the lungs is an effective method for rapid and precise delivery of the medicinal to the organ or organs in need. This technique avoids transport of the medicinal through the gut-blood barrier and its passage through the hepatic route, both of which can cause degradation of the medicinal. 
     In an example, the purification and coating processes described above can include re-processing the coated substrate or transport by heating the coated substrate such that the herbal extract(s) on the coated substrate or transport belt are re-vaporized and then condensed onto a new substrate. This can be used to further purify the herbal extract(s) in the coated substrate and can be repeated until a desired purity of the at least one of herbal extract(s) is achieved. 
     An amount of the herbal extract(s) components in or on the coated substrates can be determined as part of the process for forming the coated substrate and the delivery cartridges described below. As described above, process control methods can be implemented to control, for example, a thickness of the coating on the substrate. Based on sampling of the source material, a composition of the coating on the substrate can also be determined. Other known techniques can be used to determine a composition of the coating on the substrate. As such, an amount of the herbal extract(s) component can be determined per unit area of the coated substrate. This can be used to determine an appropriate surface area of the delivery cartridge if there is a specified amount of the herbal extract(s) in the delivery cartridge. Similarly, if the surface area of the delivery cartridge is specified, the thickness of the coating on the substrate can be adjusted in order to meet a specified amount of the herbal extract(s) in the delivery cartridge. The methods described herein for forming the coated substrates and the delivery cartridges can be used to effectively and accurately determine a composition and amount of the herbal extract(s) which can be used for dosage control. 
     Coated substrates as described herein containing herbal extract(s) can be used to form a three-dimensional structure configured for use as a delivery product. In an example, a coated substrate can be used as a delivery cartridge in a delivery device. As used herein, a delivery cartridge can refer to a replaceable element in a delivery system that is slowly depleted of herbal extract(s) as a consequence of continued use or intervals of use. The delivery cartridge can be replaced for continued use of the delivery system. In an example, delivery cartridges can be designed to maximize surface area exposed to an air flow while minimizing package volume. 
     Coated substrates can take many structural forms. In an example, coated substrates can include, but are not limited to, cubes, cones, parallelenebulizerds, or other three-dimensional shapes. In an example, a coated substrate can be in the form of a sheet. As used herein, a sheet can be any three-dimensional structure defined by a first dimension, a second dimension and a third dimension where the first dimension is much smaller than the second and third dimensions. In an example, a sheet can be generally rectangular in shape with a first end and a second end opposite the first end. 
       FIG. 7A  shows an example of a coated substrate  700  of the present disclosure which can be formed using the techniques described above or generally known in the art, examples of which are described above for extracting and purifying herbal extract(s) and coating the herbal extract(s) on a substrate. The substrate coated with herbal extract(s)  700  can include a substrate component  710 , and herbal extract(s)  720  coated on the substrate component  710  and spacers  722  located on the substrate component  710  or the herbal extract(s) component  720 . In an example, the spacers  722  can be located on the substrate component  710  before the substrate component  710  is coated. In an example, the spacers  722  can be located on the herbal extract(s) component  720  after the substrate component  710  is coated. 
       FIG. 7B  shows an example where the substrate coated with herbal extract(s)  700  can be converted into a three-dimensional structure configured for use as a delivery cartridge  702 . In an example, the substrate coated with herbal extract(s)  700  can be rolled into a spirally wound cylindrical shape to form the delivery cartridge  702 . In an example, the plurality of spacers  722  can be used as a structural element to maintain channel(s)  724  between layers of the delivery cartridge  702  to allow for the passage of heated air. The delivery cartridge  702  can include any number of layers. 
     The delivery cartridge  702  can be used with a delivery device, an example of which is described below and shown in  FIG. 17 . In an example, the delivery device can include, but is not limited to a vaporizer, an e-cigarette device, a nebulizer or an aerosol device. Alternatively, the delivery cartridge  702  can be used by directly applying heated air to the delivery cartridge  702  to volatilize or entrain molecules of the herbal extract(s) from the delivery cartridge  702 . In an example, heated air can be directly applied to the delivery cartridge  702  by any heating process or heating device that can include, but is not limited to, a vaporizer, an e-cigarette device, a nebulizer or an aerosol device In an example, heated air can be directed through the channel  724  to volatilize, and/or entrain as a solid-gas aerosol, molecules of the herbal extract(s) from the delivery cartridge  702 . 
       FIG. 8  shows a flow chart of an exemplary process to construct a spirally wound cylindrical shape, similar to the cartridge  702  of  FIG. 7B . In an example, step  810  can include providing a supply of herbaceous plant material; step  820  can include heating the herbaceous plant material to a first temperature to release a first vapor or wet extraction to produce a solution; step  830  can include condensing the first vapor or depositing and evaporating the solution onto a substrate to create a coated substrate; step  840  can include placing spacers on the coated substrate to allow for airflow through the cartridge; step  850  can include rolling the coated substrate to form a spirally-wound cylindrical shape configured for use as a delivery cartridge. 
       FIG. 9  shows an example of a coated substrate shaped in a saw-tooth, zig-zag, or accordion configuration. In an example, the saw-tooth coated substrate  900  includes a first coating  910  where the first coating  910  can be one of one or more herbal extracts. In an example, the saw-tooth coated substrate  900  includes a second coating  920  where the coating  920  can be another of the herbal extract(s) 
       FIG. 10  shows an example of a two-substrate assembly  1070  where a first saw-tooth coated substrate  1035  and a second saw-tooth coated substrate  1045  can be stacked for use as delivery cartridge. In an example, a plurality of spacers  1022  can be used as structural elements to maintain a plurality of channels  1024  between the first saw-tooth coated substrate  1035  and the second saw-tooth coated substrate  1045  to allow for the passage of heated air. In an example, the two-substrate assembly  1070  can be stacked so that the first coating  1010  of the first saw-tooth coated substrate  1035  can face the second coating  1020  of the second saw-tooth coated substrate  1045 . In an example, a plurality of two substrate assembly  1070  can be stacked for use as a delivery cartridge. 
       FIG. 11  shows an example of a two-substrate assembly  1170  where the first coating  1110  of a first saw-tooth coated substrate  1135  can face the first coating  1110  of a second saw-tooth coated substrate  1145 . In an example, a plurality of two-substrate assembly  1170  can be stacked for use as a delivery cartridge. 
       FIG. 12  shows an example of a process to construct a saw-toothed delivery cartridge. In an example, step  1210  can include providing a supply of herbaceous plant material; step  1220  can include heating the herbaceous plant material to a first temperature to release a first vapor or wet extracting a first extract to form a solution; step  1230  can include condensing the first vapor or depositing and evaporating the solution onto a first side of a substrate; step  1240  can include heating a second herbaceous plant material to a second temperature to release a second vapor or performing a second wet extraction step; step  1250  can include condensing the second vapor or depositing and evaporating the second solution onto a second side of the substrate; step  1260  can include creating a plurality of notches in the coated substrate; step  1270  can include articulating the segments to form a saw-tooth pattern and step  1280  can include stacking the substrate for use as a delivery cartridge. The process of  FIG. 12  can be modified to incorporate the multiple substrate assemblies shown in  FIGS. 10 and 11 . 
       FIGS. 13A and 13B  show top and side views, respectively, of an example of a polygonal delivery cartridge  1300 . In an example, the cross-sectional shape of the polygonal delivery cartridge can include, but is not limited to, a three-side cross-section, a four-sided cross-section or an “n”-sided cross-section where “n” can be any number equal to or greater than 3. 
       FIG. 13C  shows notches  1370  formed in the substrate  1310  and the coating  1320  that can allow a segment  1375  to articulate with respect to an adjacent segment  1375 . As used herein, a segment  1375  is the portion of the substrate  1310  and coating  1320  located between two notches  1370 . 
       FIG. 14  shows an example of a process to construct a closed polygonal shaped delivery cartridge similar to the star-shaped cartridge  1300  of  FIG. 13 . In an example, step  1410  can include providing a supply of herbaceous plant material; step  1420  can include heating the herbaceous plant material to a first temperature to release a first vapor or wet extraction to produce a first solution; step  1430  can include condensing the first vapor or depositing and evaporating the first solution onto a substrate to create a coated substrate; step  1440  can include creating a plurality of notches and step  1450  can include articulating the segments to form a saw-tooth pattern; and step  1460  can include connecting the first end to the second end to form a polygonal shape. In an example, step  1460  can include manipulating the segments to align the segments in a desired orientation relative to one another. 
     Other shapes can be used for a delivery cartridge. Any of the examples described and shown in  FIGS. 7, 9, 10, 11 and 13A-13C  can include additional layers of substrate and each layer of substrate can include one or more coating layers. As stated above in reference to  FIG. 7B , the delivery cartridges described herein can be used alone or in combination with a delivery device. Each delivery cartridge can be designed such that heated air can be passed through the cartridge and one or more herbal extract(s) can be volatilized or entrained and inhaled by a user. 
     Dimensions of any of the delivery cartridges described herein can depend, in part, on whether a delivery device is intended to be used with the cartridge and a particular design of the delivery device. These dimensions can include a length, width and overall shape of the delivery cartridge and can depend on the length and width of the coated substrate used to form the delivery cartridge. The dimensions of the delivery cartridge can also depend, in part, on an amount of the herbal extract(s) in the delivery cartridge and an intended dosage of the herbal extract(s). 
       FIG. 15  shows an exploded view of an example of an assembly  1500  comprising multiple layers of coated substrates. In an example, an herbal extract layer  1550  can include a substrate  1552  with a first surface and a second surface where a first herbal extract coating  1556  can be applied to the first surface and a second herbal extract coating  1557  can be applied to the second surface. In an example, a taste layer  1560  can include a substrate  1562  having a taste coating  1566  applied to the substrate  1562  to enhance or mask the user sensation as some but not all herbal extracts have bitter and/or unpleasing tastes and/or odors. In an example, the taste coating  1566  can include a flavoring that can include, but is not limited to, fresh mint and/or a volatile sweetening agent such as sorbitol. In an example, an adjuvant layer  1570  can include a substrate  1572  having an adjuvant coating  1576  applied to the substrate  1572  where the adjuvant coating  1576  can include at least a second compound that can augment the therapeutic effect of the herbal extract. In an example, the second compound can include, for example, a volatizable adjuvant for medicinal agents, the adjuvant being, for example, paraffin oil or squalene. In an example, an amelioration layer  1580  can include a substrate  1582  having an amelioration coating  1586  applied to the substrate  1582  where the amelioration coating  1586  can include at least a third compound that can minimize any undesirable side effects of herbal extracts, if applicable. In an example, the active herbal extracts layer  1550 , the taste layer  1560 , the adjuvant layer  1570  and the amelioration layer  1580  can be assembled together or in any permutation. In a further example incorporating any or all of the foregoing features of the coatings applied to the substrate, an herbal extract applied as first or second coating  1556  or  1557  respectively to the first or second surfaces of substrate  1552  may be one or more  cannabis  extracts such as THC and/or CBD or may be one of the herbal extracts delineated in the foregoing list of extracts. Preferably, the coatings may be a combination of  cannabis  extracts with one of the other herbal extracts. More preferably, the coatings may be a combination of  cannabis  extracts and an adjuvant or flavoring. In an example, the assembly  1500  can be converted into a three-dimensional structure for use as a delivery cartridge as described above. In other examples, an assembly can include any number and combination of layers depending on desired properties of the assembly. In an example, spacers similar to the spacers  722  shown in  FIGS. 7A and 7B  can be placed between each layer prior to forming the three-dimensional structure to allow for the passage of air between the layers. 
       FIG. 16  shows an example of a process used to make a delivery cartridge where the coated substrate includes two or more layers where at least one provides flavor or adjuvant. In an example, step  1610  can include providing a supply of herbaceous plant material; step  1620  can include heating or wet extracting the herbaceous plant material to release a first vapor or produce a first solution; step  1630  can include condensing the first vapor or depositing and drying the first solution onto a substrate to create a coated substrate; step  1640  can include attaching one or more layers to the coated substrate where the one or more layers provide at least one of flavor or adjuvant of the at least one of one or more herbal extracts, and step  1650  can include converting the substrate into a three-dimensional structure for use as a delivery cartridge. In an example, an additional step can be performed between steps  1630  and  1640  which can include heating or wet extracting the second, different herbaceous plant material to release a second vapor or to produce a second solution and subsequently condensing the second vapor or depositing and drying the second solution onto the substrate, thus creating a second coating on the coated substrate, as described above. 
     As described above in reference to the coated substrates, a composition and amount of the herbal extract(s) in the delivery cartridge can be determined and controlled, which can be used for dosage control of the herbal extract(s). In an example, the delivery cartridges can contain a predetermined quantity of herbal extract(s) and can be designed as single dosage or multi-dosage cartridges. Using the control parameters described above, a quantity of herbal extract(s) in the delivery cartridge can vary depending, for example, on the intended use of the herbal extracts. 
     A delivery cartridge can cooperate with a delivery device that supplies a volatilizing heat source to deliver the herbal extract(s) in the delivery cartridge to a user. In an example, the delivery device can include, but is not limited to, an e-cigarette, a bong, a water nebulizer and a vaporizer. 
       FIG. 17  shows a delivery cartridge  1750  in combination with an example of a delivery device, an electronic nebulizer  1700 . In an example, the electronic nebulizer  1700  and the delivery cartridge  1750  form a delivery system. The electronic nebulizer  1700  can include a heating element  1710  with an opening  1715  sized and shaped to receive the delivery cartridge  1750 , a power unit  1717 , an air intake  1720 , a moisturizing and cooling chamber  1730 , a mouthpiece  1740 , a cover  1760 , a power switch  1762  and a digital readout  1764 . 
     The heating element  1710  can heat the delivery cartridge  1750  to a specified temperature. In an example, the heating element  1710  can pre-heat the delivery cartridge  1750  to a temperature less than a volatizing or entraining temperature of the herbal extracts so that the delivery cartridge  1750  can readily volatize or entrain the molecules of the herbal extract on user demand. In an example, the heating element  1710  can heat the delivery cartridge  1750  to a temperature greater than or equal to a volatizing or entraining temperature of the herbal extract(s) to volatize or entrain the herbal extract(s) for delivery of the volatized herbal extracts on user demand. 
     The air intake  1720  provides makeup air to the electronic nebulizer  1700 . In an example, the air intake  1720  can be a hole located in the electronic nebulizer  1700  in communication with the opening  1715 , the moisturizing and cooling chamber  1730  and the mouthpiece  1740 . In an example, the air intake  1720  can allow makeup air to flow into the electronic nebulizer  1700  when a user induces a negative pressure (or suction) action at the mouthpiece  1740 . 
     The cover  1760  can prevent users from contacting the heating element  1710  during operation of the electronic nebulizer  1700 . In an example, the cover  1760  removably attaches to the electronic nebulizer  1700  to prevent loss of the delivery cartridge  1750  during use. 
     The power switch  1762  controls the flow of electrical power from a power unit  1717  to the heating element  1710 . In an example, electrical power can flow from the power unit  1717  to the heating element  1710  when the power switch  1762  is in an ‘on’ position. In an example, electrical power can be prevented from flowing from the power unit  1717  to the heating element  1710  when the power switch  1762  is in an ‘off’ position. 
     The delivery cartridge  1750  can be used with the electronic nebulizer  1700  to deliver a predetermined and accurate quantity of volatized or entrained herbal extract(s) to a user. As described above, the amount of the herbal extract(s) in the cartridge  1750  can be controlled and thus known. The cartridge  1750  can be a single dose cartridge or intended for use over multiple doses. In an example, a user can remove the cover  1760  from the electronic nebulizer  1700  and insert a delivery cartridge  1750  into the opening  1715 . In an example, the user can removably attach the cover  1760  to the electronic nebulizer  1700  before adjusting the power switch  1862  to the ‘on’ position in order to preheat the delivery cartridge  1750 . In an example, the user can monitor the digital display  1764  for a visual cue that indicates that the electronic nebulizer  1700  is ready for use. 
     A delivery device can be configured to control the dosage of the herbal extract(s) to the user such that a multi-dose cartridge can be used with the delivery device, while still maintaining dosage control. For example, a delivery device similar to the electronic nebulizer  1700  can be configured to deliver a predetermined amount of herbal extract(s) per inhalation. 
     The delivery device can control how much air passes through the delivery cartridge and how much air is delivered to the user. In an example, a valve device inserted into the air flow of the delivery device can be used to control the volume of air available to the user. For example, the valve device can be located in the mouthpiece of a delivery device to throttle the volume of air flowing through the mouthpiece. In an example, the valve device can include, but is not limited to, a flapper valve, a ball valve, a gate valve, a butterfly valve, a duckbill valve or an adjustable orifice. 
     In an example, the valve device can include a timer device that can cause the valve device to open or close after an interval of time to regulate air flow through the delivery device. For example, the valve device can include an open-loop timer device utilizing mechanisms such as a spring or a mechanical linkage to open or close the valve device. In another example, the valve device can include a closed-loop timer device using an actuator, an electrical control circuit and one or more feedback sensors to implement a control algorithm to open and close the valve. 
     The delivery device can also control other parameters that impact the amount herbal extracts(s) delivered to the user, including, for example, a temperature that the cartridge is heated to and the rate of airflow. Because the delivery cartridge only contains the desired components, which have already been separated from the undesirable components in the source material, sufficient heat can be applied to the delivery cartridge to quickly vaporize or entrain the herbal extract(s) without worrying about the undesirable components also being vaporized. 
     The delivery cartridge can be configured to control the amount or dose of herbal extract(s) delivered. In an example, the delivery cartridge can be coated with a micro porous film to control the flow of herbal extract(s) vapor or entrained microparticles from the delivery cartridge. For example, the diameter of the pores in the micro porous film applied to the coated substrate can be sized to control the dose of herbal extract(s) delivered. In an example, the coated substrate used to form a delivery cartridge can be coated with a micro porous film to control the flow of herbal extract(s) vapor or entrained herbal microparticles from the coated substrate and thereafter formed into a delivery cartridge. 
     In an example, the delivery cartridge can be constructed from a coated substrate comprising a conductive material. In an example, the conductive material can include, but is not limited to, aluminum. In an example, an electrical power circuit can be connected to the conductive material to resistively heat the conductive material to a temperature sufficient to volatilize or entrain the herbal extract(s) on the coated substrate. In an example, the electrical power circuit can include an electrical control circuit and one or more feedback sensors to resistively heat the conductive material to a sufficient temperature and thereafter accurately maintain the temperature over a period of time. 
     In an example, the delivery cartridges described herein can be used with a vaporizer or entrainer. The vaporizer or entrainer can be configured to include a chamber or receptacle into which the delivery cartridge can be placed. The delivery cartridge can be configured as a single dose or multi-dose cartridge. Given the control parameters that can be used in the process of making the delivery cartridge, the delivery cartridge can include a known quantity of the herbal extract(s). As similarly stated above, a heating temperature of the vaporizer or entrainer is not a significant concern because the delivery cartridge only includes the desired herbal extract(s) and the substrate used in forming delivery cartridge can be inert at these operating temperatures. 
       FIG. 18  shows an example of a cylindrically rolled sheet  1802 , which can be suitable for use as a delivery cartridge with a delivery system. The term cylindrical, as used herein, is intended to mean that the cross-sectional shape of the rolled sheet is the same at each longitudinal location along the rolled sheet  1802 . For instance, the cross-section itself can be a circle, a spiral, a curve that lacks sharp corners, a curve that includes at least one sharp corner, a combination of curved and straight portions, a polygon, a square, a star shape, and other suitable shapes. In some examples, the cylindrically rolled sheet can form a tunnel structure that can support air flow there through. The rolled sheet  1802  of  FIG. 18  is but one example of a cylindrical structure for use as a delivery cartridge. As described below, a cylindrical closed-end structure, such as a tube or a star can alternatively be used. 
     As described above and shown in the figures, any suitable shape can be used for the delivery cartridge, and the shape and design is not limited to the examples described and shown herein. As described above, the delivery cartridge can be cylindrical such that the cross-sectional shape is the same at each longitudinal location. In other examples, non-cylindrical designs can be used in which the cross-sectional shape varies longitudinally. In other examples, the delivery cartridge can be further converted to have a shape configured for use with different delivery systems. Further converting can include, for example, shaping a cylindrical structure into a J or an S for use in a nebulizer. 
     Referring back to  FIG. 18 , the rolled sheet  1802  includes a substrate  1803 , which can be formed from an electrically conductive material, such as aluminum, copper, or another suitable metal or metal alloy. The rolled sheet  1802  is shaped to allow a gaseous flow in its interior, along the longitudinal direction (Z), from a first longitudinal end  1826  to a second longitudinal end  1828  opposite the first longitudinal end  1826 . As further described below, all or a portion of the substrate  1803  can be covered with a coating of herbal extract(s). As described above, in some examples, the herbal extract(s) component can include one or more herbal extracts on one or both sides of the substrate  1803 . 
     The rolled sheet  1802  can include a first electrode  1804  extending laterally (X) across the substrate  1803  at a first longitudinal location  1806 . In some examples, the first electrode  1804  can be formed integral to the substrate  1803  to form the rolled sheet  1802 , for example, by extruding the electrode  1804  onto the substrate  1803 . In those examples, the first electrode  1804  can be thicker relative to the substrate  1803 . In some examples, the first electrode  1804  can be originally separate from the substrate  1803  and attached to the substrate  1803 , so that the first electrode  1804  is electrically coupled to the substrate  1803  to form the rolled sheet  1802 . This is described further below. In some examples, the first electrode  1804  can extend outward from the rolled sheet  1802 , toward an exterior of the rolled sheet  1802 . In other examples, the first electrode  1804  can extend inward from the rolled sheet  1802 , toward an interior of the rolled sheet  1802 . In still other examples, the first electrode  104  can extend both outward and inward from the rolled sheet  1802 . 
     The first electrode  1804  can be formed from an electrically conductive material and can be formed from the same or a different material than the substrate  1803 . Example materials include, but are not limited to, aluminum, copper, or another suitable metal or metal alloy. The particular material selected can depend in part on whether the first electrode  1804  is integral to or separate from the substrate  1803 . The first electrode  1804  can act a contact portion for use within a housing of an herbal extract(s) delivery system having corresponding electrodes, as described further below. 
     In an example in which the first electrode  1804  is separate from the substrate  1803 , the first electrode  1804  can be made of steel and welded to the substrate  1803  to form the rolled sheet  1802 . In such an example, the steel material can optionally be formed or provided as a coiled spring which can be straightened out to weld the material to the substrate and then the material can coil back up as the substrate  1803  is rolled to form the rolled sheet  1802 . Other materials and other assembly methods can be used to form the rolled sheet  1802  out of the substrate  1803  and first electrode  1804 . 
     The rolled sheet  1802  can also include a second electrode  1808  extending laterally (X) across the rolled sheet  1802  at a second longitudinal location  1810 . The second electrode  1808  can be similar to the first electrode  1804  and have the properties described above. The first and second electrodes  1804 ,  1808  can each have an electrical resistance small enough to conduct current laterally (X direction) along the rolled sheet  1802  without heating the rolled sheet  1802 . The second electrode  1808  can also be formed as a thick portion of the rolled sheet  1802 , or formed separately from the rolled sheet  1802  and attached to the rolled sheet  1802 , as described above with reference to the first electrode  1804 . 
     The rolled sheet  1802  can include a first substrate portion  1812  extending longitudinally (Z direction) between the first and second electrodes  1804 ,  1808 . The first substrate portion  1812  can have an electrical resistance high enough to conduct current longitudinally (Z) between the first and second electrodes  1804 ,  1808  and resistively heat the first substrate portion  1812  in response to the current conducted there through. 
     A first dose  1814  of an herbal extract(s) can be disposed on the first substrate portion  1812  of the substrate  1803  and configured to volatilize or entrain into vapor or aerosol in response to the resistive heating of the first substrate portion  1812 . In some examples, the first dose  1814  of the herbal extract(s) can be uniformly coated on the first substrate portion  1812 . In other examples, the first dose  1814  of the herbal extract(s) can include discrete pieces of multiple herbal extract(s) adhered to the first substrate portion  1812 . In some examples, the herbal extract(s) can be coated on an exterior side of the substrate  1803  in the area identified as the first portion  1812 . In some examples, the herbal extract(s) can be coated on an interior side of the substrate  1803  in the area identified as the first portion  1812 . In some examples, the herbal extract(s) can be coated on both the interior and exterior sides of the substrate  1803 . In some examples, different herbal extract(s) or combinations of herbal extract(s) can be coated on the interior and exterior sides of the substrate  1803 . 
     In some examples, the rolled sheet  1802  can further include a third electrode  1816  extending laterally (X) across the rolled sheet  1802  at a third longitudinal location  1818 , so that the second electrode  1808  is positioned longitudinally between the first and third electrodes  1804 ,  1816 . The third electrode  1816  can have an electrical resistance small enough to conduct current laterally (X) along the rolled sheet  1802  without heating the rolled sheet  1802 . The third electrode  1816  can also be formed as a thick portion of the rolled sheet  1802 , or formed separately from the rolled sheet  1802  and attached to the rolled sheet  1802 . 
     In some examples, the rolled sheet  1802  can further include a second substrate portion  1820  extending longitudinally (Z) between the second and third electrodes  1808 ,  1816 . The second substrate portion  1820  can have an electrical resistance high enough to conduct current longitudinally (Z) between the second and third electrodes  1808 ,  1816  and resistively heat the second substrate portion  1820  in response to the current conducted there through. 
     A second dose  1822  of the herbal extract(s) can be disposed on the second substrate portion  1820  and configured to volatilize or entrain into a vapor or aerosol or in response to the resistive heating of the second substrate portion  1820 . In some examples, the first and second doses  1814 ,  1822  include doses of the same herbal extract(s). In other examples, the first and second doses  1814 ,  1822  include doses of different herbal extract(s). 
     In some examples, the rolled sheet can include more than three electrodes, with a corresponding substrate portion between each pair of adjacent electrodes, and an herbal extract(s) dose disposed on each substrate portion of the substrate  1803 . As described below in reference to  FIGS. 22 and 23 , a controller can be used to regulate how and when the herbal extract(s) doses are delivered to an individual. 
       FIG. 19  shows a cross-section of the rolled sheet  1802  of  FIG. 18 . In this example, the substrate  1803  is rolled to form a cylindrical structure having a spiral cross-section, when viewed from the first longitudinal end  1826  ( FIG. 18 ) of the rolled sheet  1802 . The first, second, and third electrodes are omitted from  FIG. 19  for clarity. 
       FIG. 20  shows the cross-section of the rolled sheet  1802  from  FIG. 19 , with the addition of an optional plurality of electrically insulating spacers  2024  positioned to space apart adjacent layers of the substrate  1803 . The spacers  2024  can be similar to the spacers described above in reference to  FIGS. 7A and 7B . The electrically insulating spacers  2024  can be positioned and spaced apart to allow a gaseous flow in the interior of the rolled sheet  1802 , along the longitudinal direction, from the first longitudinal end  1826  ( FIG. 18 ) to the second longitudinal end  1828  ( FIG. 18 ). The spacers  2024  can be added to the substrate  1803  prior to forming the rolled sheet  1802  or after the rolled sheet  1802  is assembled. 
     In the examples of  FIGS. 18-20 , the substrate  1803  is rolled in an open-ended manner to form the rolled sheet  1802 , so that one of its lateral edges  2026  is disposed at the center of the rolled sheet  1802  and the opposite lateral edge  2028  is disposed at the exterior of the rolled sheet  1802 . In other examples, the substrate  1803  can be assembled in a closed-ended manner, so that for some methods of assembly, its lateral edges can be joined during assembly to form a tube or other cylindrical structure. 
       FIG. 21  shows an example of a tube  2102 , suitable for use as a delivery cartridge in delivery system. In the example of  FIG. 21 , the tube  2102  has a circular cross-section, when viewed from a longitudinal end  2126  of the tube  2102 . The tube  2102  is formed of a substrate  2103 , and as described above, all or a portion of the substrate  2103  can be coated with herbal extract(s). The tube  2102  includes a first electrode  2104  at a first longitudinal location  2106 , a second electrode  2108  at a second longitudinal location  2110 , a first substrate portion  2112  extending longitudinally (Z) between the first and second electrodes  2104 ,  2108 , a first dose  2114  of an herbal extract disposed on the first substrate portion  2112 , a third electrode  2116  disposed at a third longitudinal location  2118 , a second substrate portion  2120  extending longitudinally (Z) between the second and third electrodes  2108 ,  2116 , and a second dose  2122  of an herbal extract disposed on the second substrate portion  2120 . In some examples, only one side of the substrate  2103  is coated with the herbal extract(s) such that the herbal extract doses are disposed on the exterior of the tube  2102  or the interior of the tube  2102 . In some examples, both sides of the substrate  2103  are coated with the herbal extract(s) such that the herbal extract(s) doses are disposed on the interior and exterior of the tube  2102 . 
     In an example in which the cylindrical structure is a tube, like the tube  2102 , the tube  2102  can be formed in at least the two ways described herein. Other processes can alternatively or additionally be used to form the cylindrical structure. In a first process, the first electrode  2104  can be open and have a lateral dimension generally equal to a lateral dimension of the substrate  2103 . The first electrode  2104  can include a hinge, which can be generally located at a lateral mid-point on the first electrode  2104 . It is recognized that the hinge can be at other lateral locations on the first electrode  2104 , and more than one hinge can be used. The first electrode  404  and the substrate  2103  can be brought together such that the first and second lateral ends of each of the substrate  2103  and the electrode  2104  are generally aligned. The first and second lateral ends of the substrate  2103  and the electrode  2104  can then be connected together to form a closed, tubular structure, with the electrode  2104  connected to an exterior circumference of the substrate  2103 . Additional electrodes can similarly be attached to the substrate  2103  to form a tube having multiple electrodes at various longitudinal locations on the substrate  2103 . 
     In a second process, the first electrode  2104  can be a closed-end structure, having a generally circular shape; the substrate  2103  can be converted into a tube by joining the first and second longitudinal ends of the substrate  2103 . The converted substrate  2103  can then be inserted into the circular electrode  2104  such that the electrode  2104  is connected to an exterior circumference of the substrate  2103 . If the tube  2102  is intended to have multiple electrodes, the converted substrate  2103  can be separately inserted into each electrode, or the multiple electrodes can be longitudinally spaced from one another and the converted substrate  2103  can be inserted into the multiple electrodes in one step. In some examples, a support structure can be used to support the one or more electrodes as the converted substrate  2103  is inserted into the one or more electrodes. 
     One of ordinary skill in the art will appreciate that the delivery cartridge can have any suitable cross-section, such as spiral ( FIGS. 17-20 ), circular ( FIG. 21 ), elliptical, rounded and elongated, square, star-shaped, regular and irregular polygonal, and so forth. 
       FIGS. 22 and 23  show an example of a delivery system  2200 . The delivery system  2200  can include a delivery cartridge  2202 , which can be similar to the rolled sheet  1802  ( FIGS. 17-20 ) or alternatively can be a tube such as the tube  2102  ( FIG. 21 ). The delivery system  2200  can further include a housing  2230 .  FIG. 5  shows the rolled sheet  2202  separate from the housing  2230 , which is how the delivery system  2200  can be arranged as sold or during storage.  FIG. 23  shows the rolled sheet  2202  inserted into the housing  2230 , which is how the delivery system  2200  can be arranged during use. 
     In some examples, the housing  2230  can be configured to be reusable, and the rolled sheet  2202  can be configured to be disposable or recyclable after the herbal extract dosages have been delivered. In some of these examples, the rolled sheet  2202  can be packaged as a replaceable cartridge. In other examples, the housing  2230  and rolled sheet  2202  can be packaged together, with one or both being configured to be disposable or recyclable after the herbal extracts dosages have been delivered. In some examples, the housing  2230  can be elongated and can include a first longitudinal end configured to deliver the volatilized gas into a user&#39;s mouth. 
     The housing  2230  can be configured to receive the rolled sheet  2202  within a cylindrical cavity  2232 . The cylindrical cavity  2232  can be accessed through an opening  2234  in the housing  2230 . In some examples, such as the example of  FIG. 22 , the opening  2234  can face a user, during use. In some of these examples, the opening  2234  is configured to deliver the aerosol or vapor into a user&#39;s mouth. For these examples, the housing  2230  can include an air filter  2236 , attached to or made integral with the housing  2230 , positioned on an opposite side of the cylindrical cavity  2232  as the opening  2234 , and configured to filter air intake as air flows from outside the housing  2230 , through air filter  2236 , toward the cylindrical cavity  2232 . In other examples, the opening  2234  can face away from a user, during use. In these examples, the rolled sheet  2202  can optionally include an air filter. In some examples, the cylindrical cavity  2232  and the rolled sheet  2202  can be keyed, or can include one or more locating features that can ensure that the rolled sheet  2202  is inserted into the cylindrical cavity  2232  with a specified rotational orientation. The housing  2230  can be designed to receive delivery cartridges having alternative shapes to the cylindrical design of the delivery cartridge  2200  by having the cavity  2232  in the housing  530  be sized and shaped to correspond to the size and shape of the delivery cartridge. 
     The housing  2230  can include a first housing electrode  2238  around a circumference of the cylindrical cavity  2232  and facing inward toward the cylindrical cavity  2232 . The first housing electrode  2238  can be positioned longitudinally to respectively contact the first electrode  2204  of the rolled sheet  2202  when the rolled sheet  2202  is inserted into the housing  2230 . The first housing electrode  2238 , as well as additional housing electrodes, can be formed from stainless steel, aluminum, copper, or other suitable conductive materials. 
     The housing  2230  can include a second housing electrode  2240  around a circumference of the cylindrical cavity  2232  and facing inward toward the cylindrical cavity  2232 . The second housing electrode  2240  can be positioned longitudinally to respectively contact the second electrode  2208  of the rolled sheet  2202  when the rolled sheet  2202  is inserted into the housing  2230 . The first and second housing electrodes  2238 ,  2240  can be configured to deliver current between the first and second electrodes  2204 ,  2208  of the rolled sheet  2202 . The first and second housing electrodes  2238 ,  2240  can be part of a heating element to deliver current between the first and second electrodes  2204 ,  2208  of the rolled sheet  2202  such that a portion of the rolled sheet  2202  can be resistively heated, as an alternative to using heated air. 
     The housing  2230  can optionally include a third housing electrode  2242  around a circumference of the cylindrical cavity  2232  and facing inward toward the cylindrical cavity  2232 . The third housing electrode  2242  can be positioned longitudinally to respectively contact the third electrode  2216  of the rolled sheet  2202  when the rolled sheet  2202  is inserted into the housing  2230 . The second and third housing electrodes  2240 ,  2242  can be configured to deliver current between the second and third electrodes  2208 ,  2216  of the rolled sheet  2202 . 
     In some examples, the rolled sheet  2202  and housing  2230  can include more than three electrodes and housing electrodes, respectively. For these examples, each pair of adjacent housing electrodes can be configured to deliver current between a corresponding pair of adjacent electrodes of the rolled sheet. 
     In some examples, a controller  2244  can be positioned in the housing  2230 . The controller  2244  can be configured to deliver current to the housing electrodes  2238 ,  2240  and  2242 . In some examples, the controller can deliver current between the first and second housing electrodes  2238 ,  2240  at a first time to provide a first dose of an herbal extract to a user. In some examples, the controller  2244  can be further configured to deliver current between the second and third housing electrodes  2240 ,  2242  at a second time, different from the first time, to provide a second dose of the herbal extract to the user. For delivery cartridges that include multiple doses, the controller  2244  can be configured to deliver current between adjacent pairs of housing electrodes at sequential times to provide a dose of herbal extract to a user at each sequential time. In some examples, the controller  2244  can deliver current to multiple pairs of housing electrodes at the same time to deliver multiple doses to the user with a single inhalation. By using a conductive substrate and delivering current to the electrodes, the herbal extract(s) can be volatilized or entrained and inhaled by the user using room temperature air instead of heated air. 
     In some examples, the controller  2244  can include one or more batteries. In some examples, the controller  2244  can be rechargeable. In some examples, the controller  2244  can communicate with other electronic devices, such as through short-range wireless communication. In some examples, the controller  2244  can communicate with the Internet. In some of these examples, the controller  2244  can record a user&#39;s dosage history through wireless communication with another electronic device or through a web-based application. The controller  2244  can be triggered through a button on the housing  2230 , through a touch-sensitive area on the housing configured to activate the controller  2244  when the  2230  housing contacts a user&#39;s mouth, or through another suitable trigger. 
     During use, as a user inhales, such as through opening  2234 , the user can draw in air from the surroundings through the air filter  2236 . The air from the surroundings can combine with the dose of the herbal extract released from the rolled sheet  2202  in an optional expansion/mixing chamber  2246 . In some examples, the expansion/mixing chamber  2246  can be positioned between the rolled sheet  2202  and the user&#39;s mouth, during use. 
     After use, once the doses of the herbal extract(s) on the rolled sheet  2202  have been dispensed, the housing  2230  can eject or release the expended rolled sheet  2202 . The expended rolled sheet  2202  can then be thrown away or recycled. In some examples, the housing  2230  can optionally include storage for one or more additional rolled sheets  2202 . 
       FIG. 24  is a side-view schematic drawing of another example of a delivery system or nebulizer  2400 . The example of  FIG. 24  is sized and shaped for ease of use by a user. The delivery system  2400  can include a housing  2402 . 
     An air intake nozzle  2404  can receive air flow from the surroundings and can optionally restrict the air flow into the housing  2402 . In some examples, the air intake nozzle  2404  can be adjustable. In some examples, the air intake nozzle  2404  can allow a user to control the rate at which the surrounding air is taken into the housing  2402 . In some examples, the air intake nozzle  2404  can control a duration of an inhalation. In some examples, the air intake nozzle  2404  can produce an internal nebulizer pressure when the user inhales. 
     Air passing through the air intake nozzle  2404  can pass through an air filter  2406 . The air filter  2406  can prevent particles or particulate from entering further into the housing  2402 . In some examples, the air filter  2406  can be the same in structure and function as the air filter  2236  ( FIGS. 22 and 23 ). 
     Air passing through the air filter  2406  can enter a volatilizing or entraining chamber  2408 . In some examples, the volatilizing chamber  2408  can accommodate delivery cartridges, such as  1802  ( FIGS. 17 and 18 ),  2102  ( FIG. 21 ), or  2202  ( FIGS. 22 and 23 ). An interior of the volatilizing or entraining chamber  2408  can include electrodes that connect to corresponding electrodes on a rolled sheet during use. Air leaving the volatilizing or entraining chamber  2408  can include a prescribed dose of the herbal extract(s), which is volatilized or entrained from the cartridge during use ( 2409 ). 
     A vortex chamber  2410  can reduce a cross-section surface area of gas passing there through. The reduced surface area can increase the velocity of gas passing there through, which can be desirable. 
     Gas or vapor leaving the vortex chamber  2410  can optionally pass through a misting ring  2412 , which can optionally inject mist from a misting reservoir  2422  into the gas. In some examples, the mist can include water. In some examples, the mist can include one or more flavorings or scents. The misting reservoir can alternatively be filled with an emulsion of water and squalene or mineral oil or paraffin oil. The emulsion can act as an adjuvant in substitution for the adjuvant layer described above. 
     In some examples, the misting ring  2412  can be activated by a controller, such as  2244  ( FIGS. 22 and 23 ). In some examples, the misting reservoir  2422  is refillable. In some of these examples, the housing  2402  can define a port  2424 , through which the misting reservoir  2422  can be refilled. In some of these examples, the material to refill the misting reservoir  2422  can be poured through the port  2424  in the housing  2402 . In some examples, the material to refill the misting reservoir  2422  can be inserted via a cartridge, or other container, through the port  2424  in the housing  2402 . As described further below in reference to  FIG. 25 , a pump can be used with the reservoir  2422  to deliver the solution from the reservoir  2422  to the misting ring  2412 . As shown in  FIG. 24 , in an example, the misting reservoir  2422  can be located within the vortex chamber  2410 . In other examples, the misting reservoir  2422  can be located in an alternative location within the housing  2402  or external to the housing  2402 . 
     Gas or vapor leaving the misting ring  2412  can enter a mixing chamber  2414 . The gas or vapor, moving with an increased velocity from the vortex chamber  2410 , can expand within the mixing chamber  2414 . This expansion can form a vortex, which can improve mixing of the mist with the gas or vapor ( 2415 ). The inclusion of a misting ring in the delivery system  2400  can be used to moisturize and cool the air leaving the volatilizing chamber  2408  and can improve inhalation of the vapors or aerosol from the delivery cartridge. The mist can be added to the vapors using additional or alternative features to the misting ring  2412 . In an example, a misting solution can be packaged separately or together with a delivery cartridge. The misting solution can be available in different flavors to accommodate user preferences. It is recognized that the misting ring  2412  or comparable misting feature can be used in the other delivery systems described above. The misting ring  2412  can be used independently of the housing electrode design of  FIG. 24 . The delivery system  2400  of  FIG. 24  can alternatively exclude the misting ring  2412 . 
     Vapor or aerosol from the mixing chamber  2414  can exit the housing  2402  through a mouthpiece  2416 . In some examples, the mouthpiece  2416  is removable from the housing  2402 . A removable mouthpiece  2416  can help ensure sterility for the user. In other examples, the mouthpiece  2416  can be attached to and non-removable from the housing  2402 . 
     The housing  2402  can include an optional status indicator, which can display visual indicia that indicate a status of the housing during use. In the example of  FIG. 24 , the status indicator can include three light emitting diodes (LEDs,  2418 ) radiating outward from the housing  2402 . This is but one example of a status indicator, other suitable examples can also be used. 
     In the specific example of  FIG. 24 , each LED  2418  corresponds to a housing electrode and a corresponding electrode on the rolled sheet. In the specific example of  FIG. 24 , when the cartridge is inserted into the volatilizing or entraining chamber  2408 , the controller can sense a voltage drop across adjacent pairs of electrodes, and can direct corresponding LEDs  2418  to glow red. In this example, a red color indicates that a corresponding dose on the rolled sheet is ready to be volatilized. In this example, a user can depress a button  2420  on the housing  2402 , which can instruct the housing to direct current through a corresponding portion of the substrate. The button  2420  can operate as a ‘go button’. In other examples, the button  2420  can include additional functionality with regards to operating the delivery system  2400 . In the specific example of  FIG. 24 , when the user depressed the button for the first time, for a particular rolled sheet, corresponding LEDs can alternately blink red and green. In a specific example, blinking red and green can indicate that the controller is heating a selected dose on the rolled sheet. In some examples, the heating can take a relatively short period of time, such as two seconds. In some examples, when a dose is ready to be volatilized or entrained, a corresponding LED can turn solid green. In some examples, when a user depresses the button  2420  for a second time, the controller can monitor an internal pressure, such as in the volatilizing or entraining chamber  2408  or the mixing chamber  2414 . In some examples, the controller can include a pressure sensor that detects a drop in pressure. When the pressure drops, corresponding to an inhalation by the user, the controller can volatilize or entrain the corresponding herbal extract dose on the rolled sheet. In some examples, the pressure sensor can provide a rate at which the herbal extract is being depleted to the controller. In some examples, one or more LEDs can blink at a rate indicative of the rate at which the herbal extract is depleted. In some examples, when the controller determines that a dose of the herbal extract is fully dispensed, one of more LEDs can turn off. 
     In other examples, more or less than the three LEDs  2418  can be used in the housing  2402 . The LEDs as described above are but one specific example of a status indicator; other status indicators can also be used. 
     As shown in  FIG. 24 , the delivery system  2400  can optionally include a dose selection switch  2426  as part of the electronic controller module  2502  (schematically shown in  FIG. 25 ) for selecting how many dosages are dispensed at one time from a delivery cartridge inserted in the chamber  2408 . In some examples, the dose selection switch  2426  can include settings labeled as “1”, “2”, “3”, up to the number of doses capable of being delivered from the cartridge. For example, if the dose selection switch  2426  is set to “3”, then the delivery system  2400  can dispense three doses from the cartridge at one time. In operation, the controller module  2502  is removably and electronically connected with delivery system  2400  through the interface connectors  2500 . The schematic representation of the connection and electronic control circuits of module  2502  is shown in  FIG. 25 . 
       FIG. 25  is a schematic drawing of an example of an interface connector  2500 . The interface connector  2500  can form various connections, including electrical, hydraulic, and gaseous connections, between a controller  2502  for a vaporizing or entraining delivery system such as nebulizer  2400  ( FIG. 24 ), which is the vaporizing or entraining nebulizer shown in outline form in  FIG. 25  ( 2504 ). The interface connector  2500  is but one example of a connector; other suitable connectors can also be used. The vaporizing or entraining nebulizer  2504  is an outline of for example the nebulizer shown in  FIG. 24  and can alternatively be other nebulizer shapes having similar functions. The controller  2502  can be external to the nebulizer  2504 , attachable thereto, or integrally formed therewith. The interface connector  2500 , the controller  2502  and the vaporizing or entraining nebulizer  2504  can be part of the delivery system. 
     A controllable switching matrix  2506  can control voltages directed to each electrode  2508  on a delivery cartridge usable in the vaporizing or entraining nebulizer  2504 . The controller  2502  can include a controllable current source  2510  to generate the current, and a voltage detector  2512  to monitor the voltage across the leads of the current source  2510 . The controllable switching matrix  2506  can controllably switch the electrical connection of each electrode between the two sides of the current source  2510 , thus switching or alternating a voltage applied to each electrode between a relatively low value and a relatively high value. When the relative voltages between a pair of adjacent electrodes  2508  are equal (e.g., both relatively low or both relatively high), then no current flows between the electrodes  2508 . When the voltages between the pair of adjacent electrodes  2508  are different (e.g., one relatively low and one relatively high), then current flows from the electrode having the relatively high voltage to the electrode having the relatively low voltage. The current generates heat, and the heat volatilizes the desired dose of the herbal extract, which is disposed between the electrodes  2508  in the pair, as described above. The controller  2502  can track which doses have been volatilized or entrained, so that current is directed through each adjacent pair of electrodes  2508  only a single time during use of a particular delivery cartridge. 
     As shown in  FIG. 25 , a misting reservoir and pump  2514  can be included in the same mechanical housing as the controllable switching matrix  2506  and, in an example, can be housed within the controller  2502 . The interface connector  2500  can hydraulically connect the controller  2502  to the vaporizing or entraining nebulizer  2504  such that the misting reservoir and pump  2514  can controllably direct a specified volume of mist, through the interface connector  2500 , to a mister  2516 , such as a misting ring  2412  ( FIG. 24 ). In some examples, the controller  2502  supplies a fixed volume of mist for each dose of the herbal extract. In some examples, the controller  2502  allows a user to select the volume of mist for each dose of the herbal extract. For instance, the mist volume can be selected mechanically, such as with a knob, level, or button on the housing. Alternatively, the mist volume can be selected electronically, such as by one or more buttons on the housing of the vaporizing or entraining nebulizer  2504  or the controller  2502 . 
     A pressure sensor  2518  can be included in the controller  2502 . The pressure sensor  2518  can measure one or more pressures in the delivery system  2504 , such as at an orifice  2520 , which can be located, for example, proximate to the mouth of the user. In some examples, the controller  2502  can use the pressure sensor  2518  as a trigger switch, which can trigger additional actions from the controller  2502 . When the user inhales from the vaporizing or entraining nebulizer  2504 , the pressure at a particular location, such as at the orifice  2520 , drops. The pressure sensor  2518  can detect the drop in pressure, and the controller  2502  can take a suitable action, such as directing suitable voltages to the electrodes  2508  to initiate delivery of an herbal extract dose, and/or directing the misting reservoir  2514  to dispense mist. In other examples, the controller  2502  can connect to a Get Ready/Go button on the housing, similar to the button  2420  shown in  FIG. 24 , to trigger suitable actions. 
     The interface connector  2500  can optionally include additional electrical connections between the controller  2502  and the vaporizing or entraining nebulizer  2504 . For instance, an optional LED controller  2522  can electrically connect, through the interface connector  2500 , to one or more LEDs  2524  on or in the housing. In some examples, the controller  2502  can additionally connect to a dose selection switch disposed on the housing. In some examples, the controller can electrically connect to a power source disposed on or in the housing. 
     Although several features, for example, the misting reservoir and pump  2514 , are described above as being part of the controller  2502 , it is recognized that some or all of these features do not have to be physically contained within the same housing as the controller  2502  but can still be controlled by the controller  2502 . 
     It is recognized that a delivery system, like the system  2400  of  FIG. 24 , can exclude a controller, or a controller could be used having more or less features as the controller  2502  shown in  FIG. 25 . In a delivery system that excludes a controller, a user can manually control operation of the electrodes (or other means of volatilizing or entraining the one or more herbal extracts), or similarly, the user can manually deliver a misting solution to a mixing chamber by manually activating the pump for the mist reservoir. 
       FIG. 26A  is a perspective representation and schematic of an example of a wet extraction apparatus with casting chamber for formation of a substrate coated with an herbal extract. A large container for conducting the wet extraction of herbal extract from the herbaceous plant material is the operational device for performing this process. Typically, the large container is a five portal vessel  2601  that can be any size chemical operation vessel ranging from 1 L to 10,000 L or larger. The five portals of the vessel ( 2601 A, B, C, D and E) provide access, delivery and inlet openings to the interior of the vessel. Door  2601 XT in extraction vessel  2601  allows large scale access to the interior of the vessel and enables removal of residual herbaceous plant material after the extraction process. Although any arrangement of inlet portals is within the scope of the invention, this example provide separate inlets for the various substances and solvents as well as operational devices. Inlet  2601 A is removably connected to a container (solvent container  2602 ), typically an addition funnel, with valve for variable rate introduction of solvent into the extraction vessel  2601 . Inlet  2601 B is removably connected to a stirring rod and paddle  2603 . The rod and paddle extend into the interior region of the vessel, are powered by a variable speed electric motor (not shown) and provide distribution and mixing of the plant material and solvent. Inlet  2601 C is removably connected to a hopper with slide valve for delivery of the herbaceous plant material to the vessel  2601  (delivery hopper  2604 ). Preferably the herbaceous plant material is cleaned, dried and comminuted into very small particles. Transport of the particles from the delivery hopper into the extraction vessel may be accomplished by gravity flow, pressurized delivery or mechanical transport through the delivery chute. Inlet  2601 D is removably connected to a tank of inert gas (gas tube  2605 ). If the herbal extract is oxidation sensitive, a cloud or atmosphere of inert gas such as nitrogen or argon may be introduced over the solution of solvent and plant material. Inlet  2601 E is removably connected to an outlet tube capped at its distal end with a glass frit or other screen material (outlet tube  2606 ). The outlet tube extends into the interior of the vessel and the frit or screen resides at the bottom of the extraction vessel. Outlet tube  2606  is optionally, removably connected to a trap having an inlet and outlet (trap  2607 ). The outlet tube  2606  will carry solution and residue of plant material into the trap  2607 . The trap allows the residue to settle and enables further transport of clean solution to a concentrator to remove substantially most of the solvent from the solution, provide a concentrate and the concentrate delivered to distribution tube  2608   a . If trap  2607  is not needed, it can be bypassed and solution delivered to a concentrator to remove substantially most of the solvent from the solution, provide a concentrate and the concentrate delivered to distribution tube  2608 A. 
     Distribution tube  2608 A is removably and variably connected through a Y tube with valve  2608 B to a chromatographic column  2609 A on one side of the Y tube and a fine flow spray tube  2609 B on the other side of the Y tube through a transport tube  2609 C. The valve of Y tube  2608 B directs solution flow either to cylinder  2609 A or to spray tube  2609 B through transport tube  2609 C. The outlet of cylinder  2609 A connects to a valve arrangement and hence to spray tube  2609 B. Spray tube  2609 B is movably positioned over casting basin  2610  and is designed to deliver a fine sheet of concentrate onto the casting basin. Spray tube  2609 B can be transported along the length of the casting basin so as to deliver a layer of concentrate into the casting basin. Also movably positioned over casting basin  2610  is evaporator tube  2611 . Evaporator tube  2611  is positioned at an appropriate distance behind spray tube  2609 B. Evaporator tube  2611  is connected to a tank of dry inert gas and is equipped with an exhaust hood  2612 . The combination of the evaporator tube, gas and exhaust hood enable evaporation of solvent from the cast solution in the casting basin so as to provide a dried layer of herbal extract. 
     In operation, finely divided herbaceous plant material that preferably has been cleaned and dried to remove water is placed into delivery hopper  2604 . The valve or other transport mechanism for delivery of the material to the vessel  2601  is actuated and an appropriate amount of material is delivered to the vessel. Solvent container  2602  is filled with an appropriate solvent in which it is known that the herbal extract is soluble. The solvent container valve is actuated and an appropriate amount of solvent added to the vessel  2601 . The stirring rod/paddle  2603  is actuated and the solution of solvent and plant material stirred. Heat may be applied to the solution through a heating mantle around the vessel (not shown). The temperature of the heating process can be appropriately controlled so as to increase the rate of extraction of the herbal extract from the material but not to volatilize the solvent to a great extent. Additional solvent may be added from time to time to replenish solvent loss. 
     After an appropriate time for achievement of extraction of the herbal extract from the material, gas flow from gas tube  2605  is initiated. At the same time, the valve of the solvent container  2602  is checked to assure it is closed and the gas tight seal around the stirring rod/paddle is checked to assure sealing. The flow of inert gas into flask  2601  increases the internal pressure and causes the solution to flow out through the outlet tube  2606 . The glass frit or screen at the distal end of the outlet tube  2606  provides separation of solution from residual plant material. The increased pressure inside vessel  2601  causes the solution to transport optionally into trap  2607  as the trap fills with solution, any residual plant material carried by the solution settles to the bottom of the trap. Clean solution passes from the trap outlet tube into distribution tube  2608   a . If the solution from tube  2606  is clean, trap  2607  can be bypassed and the solution delivered directly to tube  2608 A. Distribution tube  2608   a  connects with Y tube and valve  2608 B. The Y tube valve can control delivery of the solution either to a chromatography column  2609 A or to spray tube  2609 B. 
     Delivery to chromatography column  2609 A is an option for further purification of the herbal extract in the solution. The column may be a silica gel, diatomaceous earth, cellulose, cellulose derivatives, alumina, polystyrene microparticles and similar chromatographic materials. Passing the solution through the column will separate a mixture of substances in the herbal extract such that each substance will exit the column at a different time owing to its retention factor in the column material. In this fashion, a gross herbal extract can be further refined to a particular substantially purified substance. Identification of the various fractions can be made by UV and/or IR identification of the fraction at the outflow end of the column (not shown). If the column  2609 A is chosen for passage of the solution, the chromatographed, desired herbal extract exiting the column may be directed to the next appropriate step. 
     With the passage of solution through either column  2609 A or by bypassing column  2609 A, the solution can be optionally and preferably concentrated by vacuum evaporation of a significant portion of solvent. This may be accomplished for example by roto-vacuum evaporation on a rotostripper (not shown). The solution is concentrated into a concentrate with a minimum amount of solvent present to enable the concentrate to flow. 
     The concentrate from vacuum evaporation may be transported to spray tube  2609 B. The spray tube is utilized to lay down a broad flat sheet of concentrate into casting basin  2610 . Spray tube  2609 B is dimensioned so that its length spans the width of the casting basin. Spray tube  1609 B has a slit running its entire length so that the spray of concentrate out of the spray tube constitutes a continuous sheet of spray. Into casting basin  2610  is prepositioned substrate  2012 . The dimensions of the casting basin and the substrate are coordinated so that the substrate fits tightly into the casting basin. The edges of the substrate seal against the sides of the casting basin so that concentrate is unable to seep past the edges and down underneath the substrate. The edges of the casting basin are higher than the thickness of the substrate and the sheet of concentrate to be laid down so that the sheet of concentrate is held in a stationary configuration on top of the substrate. As concentrate flows out through the slit of spray tube  2608 B, the tube may be moved along the length of casting basin  2610  or spray tube  2608 B may be remain stationary above casting basin  2610 . Because the concentrate is liquid, it will seek its own uniform level on the substrate  2612  in casting basin  2610  when spray tube  2608 B is stationary. Nevertheless, transport of spray tube  2608 B along the length of casting pan  2610  is preferred. At an appropriate distance and time following the operation of spray tube  2608 B, evaporator tube  2611  is actuated to emit a sheet of inert gas to evaporate the solvent from the layer of concentrate laid down on the substrate  2612 . Evaporator tube  2611  spans the width of the casting basin and is configured with a thin slit or with a line of holes along its long axis. The slit or holes are arranged to direct a stream of inert gas substantially parallel and at some distance above the casting pan. Preferably, evaporator tube  2611  can be rotated around its long axis so as to direct to flow of inert gas upward and perpendicular to the substrate, or at any rotary angle form upward and perpendicular to downward and perpendicular. Evaporator tube  2611  also can be moved along the length of the casting basin, i.e., is translatable along the length of the casting basin so that it will translate from one end to the other of the casting basin. In operation, the evaporator tube is actuated after completion of the deposit of concentrate on the substrate. The flow of inert gas is first directed upward so as to evaporate a substantial portion of the solvent from the deposited concentrate. As the deposited concentrate become sticky to tacky and tends toward dryness, the flow of inert gas is directed more and more downward so as to continue drying and finally leaving a dried layer of herbal extract on the substrate. 
     This process can be repeated to deposit multiple layers of herbal extract. For subsequent layers, the evaporator tube preferably is operated substantially soon after the spray tube has deposited a sheet of concentrate. In this fashion, a subsequent sheet of concentrate is dried fairly rapidly as it is laid down so that the underlying layer of herbal extract is not redissolved. 
     It is preferred to include an exhaust hood above the casting basin, spray tube and evaporator tube so that evaporated solvent can be captured and disposed of without exhausting solvent into the atmosphere. 
     Solvents useful for wet extraction include water, chloroform, ether, ethyl alcohol, glyme, hexane, and similar polar protic or polar aprotic or nonpolar organic solvents having boiling point below 100° C. 
     As an alternative, as described and depicted in  FIG. 26B , a wet extraction process can be employed to produce a series of solutions of herbal extracts held in remote storage vessels  2950 A, B and C. On the other side of the process, individual hoppers  2604  A, B and C are used to deliver different herbaceous plant material to the extraction vessel  2601 . Each hopper can contain a different individual herbaceous plant material. The chutes of the individual hoppers can be actuated to deliver the herbaceous material to extraction vessel  2601  through inlet  2601 C. Following the wet extraction, the solution can be transported to an individual storage vessel, one of vessels  2650  A, B and C. The residual herbaceous material remaining in extraction vessel  2601  can be removed through door  2601 XT. 
     The storage vessels  2651  A, B and C will have inlets connected by a multi directional flow controller (a multiple position valve assembly  2630 ) to delivery tube  2609 D. The controller  2630  can direct the flow of different solutions of herbal extract to individual storage vessels  2651  A, B and C. When needed, the multi-positional valve  2952  connected to the outlets  2951  A, B and C of the storage vessels can be actuated and the appropriate solution from a chosen storage vessel delivered to a concentrator (vacuum evaporator) and the concentrate delivered to slit tube  2609   b . The concentrate from storage vessel  2950  A, B or C may be cast as an individual herbal extract layer on a substrate or as one of a multiple number of layers on a substrate as described above. 
     There can be potential advantages to delivering the herbal extract(s) using the delivery cartridges described herein. For instance, the herbal extract(s) dosage and purity can be accurately controlled during the manufacturing process. In some examples, an advantage can include allowing a user to ingest herbal extract(s) in a safe, repeatable accurate dose suitable for research and clinical trials. In some examples, an advantage can include forming the cartridge from recyclable aluminum. In some examples, an advantage can include depositing the herbal extract(s) onto the aluminum substrate in a carefully controlled and regulated process, transported to the user. In some examples, an advantage can include removing the toxins during factory processing and disposing of the toxins properly. In some examples, an advantage can include recycling the cartridge, with no waste. In some examples, an advantage can include convenience for the user, and lack of smoke when used. In some examples, an advantage can include disposing multiple doses on a single cartridge, which further enhances convenience, functionality as well as lowering shipping cost. In some examples, an advantage can include the flexibility in accurately setting a dose level, which can provide functionality to both users and researchers alike. In some examples, an advantage can include optionally adding a moisturizing mist, and perhaps a pleasant flavor, which improves the overall experience and comfort for the user. 
     Embodiments 
     The present application provides for the following exemplary embodiments, the numbering of which is not to be construed as designating levels of importance: 
     Embodiment 1 provides a method of purifying an herbal extract from an herbaceous plant composition and the method can comprise heating the composition to a first temperature to volatilize the herbal extract into a first vapor, and condensing the first vapor onto a substrate to form a first coating, the first coating comprising the herbal extract 
     Embodiment 2 provides the method of Embodiment 1 optionally configured to provide multiple layers of herbal extracts, each layer being a different herbal extract. The method comprises practice of embodiment 1 to provide a first coating and optionally further comprising, after forming the first coating, heating a second herbaceous plant composition to a second temperature to volatilize a second herbal extract into a second vapor, and condensing the second vapor onto the substrate to form a second coating over the first coating, the second coating comprising the second herbal extract. As an option of embodiment 2, one of the herbal extracts may be a  cannabis  extract. 
     Embodiment 3 provides the method of Embodiment 1 optionally configured such that the substrate includes a first side and a second side and the first coating is formed on the first side of the substrate and comprises the first herbal extract. The method optionally further comprises heating the second herbaceous plant composition to volatilize the second herbal extract into a second vapor and condensing the second vapor onto the second side of the substrate to form a second coating, the second coating comprising the second herbal extract. As an option of embodiment 3, one of the herbal extracts may be a  cannabis  extract. 
     Embodiment 4 provides the method of Embodiment 1 optionally configured such that the first coating comprises the first herbal extract and the method optionally further comprising, after forming the first coating, heating the second herbaceous plant composition to volatilize the second herbal extract into a second vapor, and condensing the second vapor onto a second substrate to form a coating comprising the second herbal extract. As an option of embodiment 4, one of the herbal extracts may be a  cannabis  extract. 
     Embodiment 5 provides the method of Embodiment 1 optionally configured such that the first temperature is equal to or greater than a temperature sufficient to volatilize the first herbal extract. 
     Embodiment 6 provides the method of any of Embodiments 1-5 optionally configured such that condensing the first vapor onto a substrate includes placing the substrate on or near a cooling bar. 
     Embodiment 7 provides the method of any of Embodiments 1-6 optionally configured such that the herbaceous plant composition is one or more of the flowers, seeds buds, leaves, stems, branches, bark and/or roots of the herbaceous plant. 
     Embodiment 8 provides the method of Embodiment 7 optionally further comprising processing the herbaceous plant composition by comminuting the flowers, buds, seeds, leaves, stems, branches, bark and/or roots into very small pieces prior to heating the raw herbal extracts. 
     Embodiment 9 provides a method of pre-treating the very small pieces of herbaceous plant material of Embodiment 8 by drying the very small pieces in air at ambient temperature to slightly above ambient temperature to remove water, and optionally collecting the removed water and separating any herbal extract present in the removed water. 
     Embodiment 10 provides the method of Embodiment 9 optionally further comprising vacuum drying the very small pieces of herbaceous plant material to produce vapors composed of water and herbal extracts, collecting the vapors by condensation and separating the herbal extracts from the water by dissolution of the herbal extracts with a water immiscible solvent. 
     Embodiment 11 provides a method of making a delivery cartridge and can comprise practice of Embodiments 1-10 followed by converting the coated substrate into a three-dimensional structure configured for use as a delivery cartridge. 
     Embodiment 12 provides the method of Embodiment 11 optionally configured such that converting the coated substrate includes rolling the coating substrate to form a spirally-wound cylindrical shape. 
     Embodiment 13 provides the method of Embodiment 12 optionally configured such that a plurality of spacers is placed along the coated substrate prior to converting. The plurality of spacers can be configured to allow for airflow through the spirally-wound cylindrical shape. 
     Embodiment 14 provides the method of Embodiment 11 optionally configured such that the coated substrate comprises a first end and a second end opposite to the first end and the method can further comprise creating a plurality of notches at multiple locations on the coated substrate between the first and second ends. The notches can create an interface and an interval between adjacent notches defines a segment of coated substrate. The method can further comprise bending the segments relative to one another at the interfaces so as to form a saw-tooth pattern. 
     Embodiment 15 provides the method of Embodiment 14 optionally further comprising connecting the first end to the second end to form a closed polygonal shape. 
     Embodiment 16 provides the method of any of Embodiments 11-15 optionally further comprising ascertaining an average amount of the herbal extract(s) in the coating per unit area of the coated substrate. 
     Embodiment 17 provides the method of any of Embodiments 11-16 optionally configured such that converting the coated substrate into a three-dimensional structure includes determining a total area of the coated substrate to use for the three-dimensional structure based on a predetermined amount of the herbal extract(s) in the delivery cartridge. 
     Embodiment 18 provides the method of any of Embodiments 11-17 optionally further comprising attaching one or more layers to the coated substrate prior to converting the coated substrate into a three-dimensional structure, the one or more layers configured to provide at least one of flavor or adjuvant substance with the herbal extract(s). 
     Embodiment 19 provides the method of any of Embodiments 11-18 optionally further comprising depositing multiple overlapping or sequential layers of herbal extract(s) on one or both sides of the substrate, the multiple layers each being a different herbal extract. 
     Embodiment 20 provides the method of any of Embodiments 11-19 optionally configured such that the vaporization temperatures for producing the herbal extract vapors are selected according to the known vaporization temperatures of the individual herbal extract(s). 
     Embodiment 21 provides a delivery product comprising a coated substrate with one or more coating layers, the one or more coating layers including one or more herbal extracts 
     Embodiment 22 provides the delivery product of Embodiment 21 optionally configured such that the coated substrate is converted into a three-dimensional structure configured to maximize surface area of the three-dimensional structure and allow for passage of air through the three-dimensional structure, in order to volatize the herbal extract(s) for inhalation by a user when heat is applied to at least one of the three-dimensional structure or the air passing through the three-dimensional structure. 
     Embodiment 23 provides the delivery product of Embodiment 22 optionally configured such that the three-dimensional structure is a cylindrical shape having multiple layers of the coated substrate, and the three-dimensional structure is formed by rolling the coated substrate into a spiral. 
     Embodiment 24 provides the acts delivery product of Embodiment 22 optionally configured such that the three-dimensional structure is tubular and includes a longitudinal opening extending from a first end to a second end of the three-dimensional structure, and a cross-section of the three-dimensional structure is a polygon. 
     Embodiment 25 provides the delivery product of Embodiment 22 optionally configured such that the three-dimensional structure is rectangular and includes multiple layers of the coated substrate folded in a saw-tooth pattern and compressed together to form the rectangular shape. 
     Embodiment 26 provides the delivery product of any of Embodiments 22-25 optionally in combination with a delivery device configured to receive the three-dimensional structure and comprising a heating element for heating the three-dimensional structure to volatilize or entrain the herbal extract(s) in the three-dimensional structure into a vapor or aerosol. 
     Embodiment 27 provides the delivery product of Embodiment 26 optionally configured to have multiple layers of herbal extracts, each layer being a different herbal extract and the volatilization or entrainment of the herbal extract(s) is simultaneous or sequential and is controlled by management of the heating temperature produced by the delivery device. 
     Embodiment 28 provides the delivery product of Embodiment 27 optionally configured to include misting of water such that a hot aerosol is passed over the delivery product and the delivery device further comprises a misting reservoir hydraulically connected to the mister. 
     Embodiment 29 provides the delivery product of any of Embodiments 22-28 optionally further comprising one or more additional layers attached to the coated substrate and configured to provide at least one of flavor or adjuvant of the one or more herbal extract(s). 
     Embodiment 30 provides the delivery product of any of Embodiments 22-29 optionally configured such that the coated substrate includes first and second electrodes extending laterally on the coated substrate at first and second longitudinal locations, the first and second electrodes each having an electrical resistance sufficient to conduct current laterally such that at least a portion of the coated substrate can be resistively heated, and the herbal extract or extracts volatilize or entrain in response to the resistive heating. 
     Embodiment 31 provides a delivery system comprising a coated substrate with one or more coating layers, the one or more coating layers including herbal extract(s), and a heating element for heating the coated substrate to a temperature to volatize or entrain the herbal extract(s) in the one or more coating layers into a vapor or aerosol inhalable by a user. 
     Embodiment 32 provides the delivery system of Embodiment 31 optionally configured such that the coated substrate is converted into a delivery cartridge configured to maximize surface area of the delivery cartridge and allow for passage of air through delivery cartridge, in order to volatize or entrain herbal extract(s) for inhalation by a user when heat is applied to delivery cartridge or the air passing through the delivery cartridge. 
     Embodiment 33 provides the delivery system of Embodiment 31 or 32 optionally configured such that the heating element is contained within the delivery device and the delivery cartridge is receivable within a receptacle of the delivery device to heat the delivery cartridge. 
     Embodiment 34 provides the delivery system of any of Embodiments 31-33 optionally configured such that the heating element is part of a vaporizer or a nebulizer. 
     Embodiment 35 provides the delivery system of any of Embodiments 31-34 optionally further comprising a mister configured to add a mist to the vapor. 
     Embodiment 36 provides the delivery system of Embodiment 35 optionally further comprising a misting reservoir hydraulically connected to the mister. 
     Embodiment 37 provides the delivery system of any of Embodiments 31-36 optionally configured such that the coated substrate includes first and second electrodes extending laterally on the coated substrate at first and second longitudinal locations, the first and second electrodes each having an electrical resistance sufficient to conduct current laterally along the substrate, the substrate having an electrical resistance high enough to conduct current longitudinally between the first and second electrodes and resistively heat at least a portion of the coated substrate in response to the current conducted there through, and the herbal extract(s) volatilizes into a gas or vapor or entrains as an aerosol in response to the resistive heating. 
     Embodiment 38 provides the delivery system of Embodiment 37 optionally configured such that the heating element includes first and second housing electrodes to deliver current between the first and second electrodes on the substrate to resistively heat at least a portion of the coated substrate. 
     Embodiment 39 provides a delivery product including a cylindrical structure extending in a longitudinal direction and formed from a substrate of an electrically conductive material. The cylindrical structure can include first and second electrodes extending laterally on the substrate at respective first and second longitudinal locations, the first and second electrodes each having an electrical resistance sufficient to conduct current laterally along the substrate, and a first substrate portion extending longitudinally between the first and second electrodes, the first substrate portion having an electrical resistance high enough to conduct current longitudinally between the first and second electrodes and resistively heat the first substrate portion in response to the current conducted there through. The cylindrical structure can also include a first dose of an herbal extract disposed on the first substrate portion and configured to volatilize or entrain into a gas or vapor or aerosol in response to the resistive heating of the first substrate portion. 
     Embodiment 40 provides the delivery product of Embodiment 39 optionally configured such that the substrate is rolled to form the cylindrical structure having a spiral cross-section, when viewed from a longitudinal end of the rolled sheet, and can optionally further comprise a plurality of electrically insulating spacers positioned to space apart adjacent layers of the substrate. 
     Embodiment 41 provides the delivery product of Embodiment 40 optionally configured such that the first and second electrodes are attached to the substrate prior to rolling the substrate to form the cylindrical structure. 
     Embodiment 42 provides the delivery product of any of Embodiments 39-41 optionally further comprising a housing configured to receive the cylindrical structure within a cavity in the housing, the cavity sized and shaped to correspond to the cylindrical structure, the housing having first and second housing electrodes around a circumference of the cavity and facing inward toward the cavity. The first and second housing electrodes can be positioned longitudinally to respectively contact the first and second electrodes of the cylindrical structure when the cylindrical structure is inserted into the housing, and the first and second housing electrodes can be configured to deliver current between the first and second electrodes of the cylindrical structure. 
     Embodiment 43 provides the delivery product of any of Embodiments 39-42 optionally configured such that the cylindrical structure further includes a third electrode extending laterally across the cylindrical structure at a third longitudinal location, so that the second electrode is positioned longitudinally between the first and third electrodes; and the third electrode has an electrical resistance small enough to conduct current laterally along the cylindrical structure. The cylindrical structure further includes a second substrate portion extending longitudinally between the second and third electrodes; and the second substrate portion has an electrical resistance sufficient to conduct current longitudinally between the second and third electrodes and resistively heat the second substrate portion in response to the current conducted there through. A second dose of the herbal extract which is the same as or different from the first dose can be disposed on the second substrate portion and configured to volatilize into a gas or vapor or entrain into an aerosol in response to the resistive heating of the second substrate portion. 
     Embodiment 44 provides the delivery product of Embodiment 43 optionally further comprising a housing configured to receive the cylindrical structure within a cavity in the housing, the cavity sized and shaped to correspond to the cylindrical structure, the housing having first, second, and third housing electrodes around a circumference of the cavity and facing inward toward the cavity, the first, second, and third housing electrodes being positioned longitudinally to respectively contact the first, second, and third electrodes of the cylindrical structure when the cylindrical structure is inserted into the housing, the first and second housing electrodes configured to deliver current between the first and second electrodes of the cylindrical structure, and the second and third housing electrodes configured to deliver current between the second and third electrodes of the cylindrical structure. 
     Embodiment 45 provides the delivery product of Embodiment 44 optionally further comprising a controller positioned in the housing and configured to deliver current between the first and second housing electrodes to provide the first dose of the herbal extract to a patient, and further configured to deliver current between the second and third housing electrodes to provide second and third doses of the herbal extract to the patient, the herbal extract of the second and third doses being the same as or different from the herbal extract of the first dose and the herbal extracts of the second and third doses being the same or being different. 
     Embodiment 46 provides the delivery product of Embodiment 45 optionally configured such that the controller delivers current between the first and second housing electrodes at a first time to provide the first dose of the herbal extract to a user and delivers current between the second and third housing electrodes at a second time and third, different from the first time, to provide the second dose and third dose of herbal extract to the user. 
     Embodiment 47 provides the delivery product of Embodiment 45 optionally configured such that the controller delivers current between the first and second housing electrodes and simultaneously delivers current between the second and third housing electrodes to provide the first, second and doses of herbal extracts to the user at the same time. 
     Embodiment 48 provides the delivery product of any of Embodiments 44-47 optionally configured such that the housing is elongated and includes a first longitudinal end configured to deliver the vapor or aerosol into a user&#39;s mouth. 
     Embodiment 49 provides the delivery product of any of Embodiments 39-48 optionally configured such that the herbal extract(s) include at least one of a coniferous extract, menthol, nutmeg oil,  digitalis , methyl salicylate, acetyl salicylic acid or the methyl ester thereof, tetrahydrocannabinol, cannabidiol, arachidonic acid, a steroid such as budesonide, mometasone or fluticasone, niacin, caffeine, cacao extract, or coca leaf extract. The purified forms of some of these extracts may be purchased as substances previously obtained from herbaceous plants and/or optionally synthetically modified. The non-salt forms, e.g., free bases, free acids and non-complexed neutral forms are preferred for volatilization and/or entrainment as vapors and/or aerosols. 
     Embodiment 50 provides the delivery product of any of Embodiments 39-49 optionally configured such that the first and second electrodes are formed integrally with the substrate and are thicker than the first substrate portion. 
     Embodiment 51 provides the delivery product of any of Embodiments 39-50 optionally configured such that the housing further comprises a mister configured to add a mist to the volatized first dose of the one or more herbal extracts. 
     Embodiment 52 provides the delivery product of Embodiment 51 optionally configured such that the housing further comprises a misting reservoir hydraulically connected to the mister. 
     Embodiment 53 provides an apparatus including a cylindrical structure extending in a longitudinal direction and formed from a substrate of an electrically conductive material. The cylindrical structure can include a plurality of electrodes extending laterally on the substrate at respective longitudinal locations, each electrode in the plurality having an electrical resistance sufficient to conduct current laterally along the substrate. The cylindrical structure can include at least one substrate portion extending longitudinally between the adjacent electrodes in the plurality, each substrate portion having an electrical resistance sufficient to conduct current longitudinally between the adjacent electrodes and resistively heat the substrate portion in response to the current conducted there through. The cylindrical structure can include herbal extract(s) disposed on each substrate portion and configured to volatilize or entrain into a vapor or aerosol in response to the resistive heating of the substrate portion 
     Embodiment 54 provides the apparatus of Embodiment 53 optionally configured such that the substrate is rolled to form the cylindrical structure having a spiral cross-section, when viewed from a longitudinal end of the rolled sheet, and optionally further comprising a plurality of electrically insulating spacers positioned to space apart adjacent layers of the substrate. 
     Embodiment 55 provides the apparatus of Embodiment 54 optionally configured such that the first and second electrodes are attached to the substrate prior to rolling the substrate to form the cylindrical structure. 
     Embodiment 56 provides the apparatus of any of Embodiments 53-55 optionally configured such that a first lateral end of the substrate is connected to a second lateral end of the substrate to form the cylindrical structure having a tubular shape, and each of the plurality of electrodes extend around an exterior circumference of the tubular shape. 
     Embodiment 57 provides the apparatus of any of Embodiments 53-56 optionally further comprising a housing configured to receive the cylindrical structure within a cavity sized and shaped to receive the cylindrical structure, the housing having a plurality of housing electrodes around a circumference of the cavity and facing inward toward the cavity, each housing electrode being positioned longitudinally to respectively contact a respective electrode of the cylindrical structure when the cylindrical structure is inserted into the housing. Each pair of adjacent housing electrodes can be configured to deliver current between a corresponding pair of adjacent electrodes of the cylindrical structure. 
     Embodiment 58 provides the apparatus of Embodiment 57 optionally further comprising a controller positioned in the housing and configured to deliver current between adjacent pairs of housing electrodes at sequential times to provide a dose of the corresponding herbal extract to a user at each sequential time, or deliver current between adjacent pairs of housing electrodes simultaneously to provide more than one dose of the corresponding herbal extract(s) to the user at one time. 
     Embodiment 59 provides the apparatus of any of Embodiments 53-58 optionally configured such that the herbal extract or extracts includes at least one of a coniferous extract, menthol, nutmeg oil,  digitalis , methyl salicylate, acetyl salicylic acid or the methyl ester thereof, tetrahydrocannabinol, cannabidiol, arachidonic acid, a steroid such as budesonide, mometasone or fluticasone, niacin, caffeine, cacao extract, or coca leaf extract. The purified forms of some of these extracts may be purchased as substances previously obtained from herbaceous plants and/or optionally synthetically modified. The non-salt forms, e.g., free bases, free acids and non-complexed neutral forms are preferred for volatilization and/or entrainment as vapors and/or aerosols. 
     Embodiment 60 provides the apparatus of any of Embodiments 53-59 optionally configured such that the housing further comprises a mister configured to add a mist to the volatilized herbal extract or extracts. 
     Embodiment 61 provides the apparatus of Embodiment 60 optionally configured such that the housing further comprises a misting reservoir hydraulically connected to the mister. 
     Embodiment 62 provides a method including forming or providing a sheet of conductive material, the sheet extending in longitudinal and lateral dimensions, the sheet having a plurality of contact portions spaced apart longitudinally and extending laterally across the sheet, the sheet having at least one substrate portion extending longitudinally between a pair of adjacent contact portions, the contact portions having a thickness greater than a thickness of the at least one substrate portion. The method including depositing an herbal extract or multiple herbal extracts on the corresponding substrate portion or portions, the herbal extract(s) being configured to volatilize into a vapor or entrain as an aerosol in response to resistive heating of the respective substrate portion, and converting the sheet into a cylindrical structure. 
     Embodiment 63 provides the method of Embodiment 62 optionally configured such that converting the sheet into a cylindrical structure includes rolling the sheet such that the cylindrical structure has a spiral cross-section, when viewed from a longitudinal end of the rolled sheet. The method can optionally further comprise, as the sheet is rolled, placing a plurality of electrically insulating spacers between adjacent layers of the sheet, the spacers being spaced apart to allow a flow of gas or aerosol there-around. 
     Embodiment 64 provides the method of Embodiment 62 or 63 optionally configured such that converting the sheet into a cylindrical structure includes connecting a first lateral end of the sheet to a second lateral end of the sheet to form the cylindrical structure having a tubular shape, and each of the plurality of contact portions extends around a circumference of the tubular shape. 
     Embodiment 65 provides the method of any of Embodiments 62-64 optionally configured such that the cylindrical structure is configured for use as a delivery cartridge. 
     Embodiment 66 provides the method of any of Embodiments 62-65 wherein the herbal extract(s) includes at least one of a coniferous extract, menthol, nutmeg oil,  digitalis , methyl salicylate, acetyl salicylic acid or the methyl ester thereof, tetrahydrocannabinol, cannabidiol, arachidonic acid, a steroid such as budesonide, mometasone or fluticasone, niacin, caffeine, cacao extract, or coca leaf extract. The purified forms of some of these extracts may be purchased as substances previously obtained from herbaceous plants and/or optionally synthetically modified. The non-salt forms, e.g., free bases, free acids and non-complexed neutral forms are preferred for volatilization and/or entrainment as vapors and/or aerosols. 
     Embodiment 67 provides a method, system, product or apparatus of any one or any combination of Embodiments 1-66, which can be optionally configured such that all steps or elements recited are available to use or select from. 
     Embodiment 68 provides a method, system, product and/or apparatus for practicing wet extraction and isolation of herbal extract(s) from one or more comminuted herbaceous plant compositions to produce one or more purified herbal extracts and deposition of one or more herbal extract on corresponding portions of a substrate to provide a substrate coated with one or more herbal extracts, the herbal extract(s) being present as overlapping layers on the substrate or as segregated layers on the substrate, the coated substrate being preferably configured to provide a delivery cartridge corresponding to a delivery system wherein the delivery system is configured to volatilize the herbal extract(s) or entrain the herbal extract(s) so as to produce a vapor or aerosol of the herbal extract(s) for administrative delivery by inhalation to a patient. 
     Embodiment 69 provides a method and product of Embodiment 68 in which the wet extraction and isolation includes formation of a concentrate of the one or more comminuted herbaceous plant compositions in one or more appropriate solvents so as to extract the herbal extract(s) from the composition or compositions and provide one or more solutions of herbal extract(s), concentrating the one or more solutions to form concentrates or optionally crystallizing the herbal extract(s) from the solutions or optionally forming neet oils of the one or more concentrated solutions and depositing and/or casting the one or more crystallized herbal extract(s) and/or one or more oils of herbal extracts and/or one or more concentrates onto the one or more corresponding portions of the substrate. 
     Embodiment 70 provides a method and product of Embodiments 68 and 69 in which the concentration of the one or more solutions is accomplished by stirred vacuum removal of solvent and the crystallization is accomplished by addition of a non-solvent for the herbal extract(s) to the concentrated solution of herbal extract(s). 
     Embodiment 71 provides a method, system, product and/or apparatus of Embodiments 68, 69 and/or 70 wherein the herbaceous plant material is pre-treated as described in Embodiments 7-10. 
     Embodiment 72 provides a coated substrate, a delivery cartridge and/or a delivery system of any of Embodiments 11-66 wherein the substrate coated with one or more overlapping or segregated layer is herbal extract(s) is produced according to the wet extraction methods of Embodiments 68, 69 and/or 70 and optionally by incorporating the pre-treatment of herbaceous plant material according to Embodiments 7-10. 
     Embodiment 73 provides an apparatus including a cylindrical structure extending in a longitudinal direction and formed from a substrate of an electrically conductive material. The cylindrical structure can include a plurality of electrodes extending laterally on the substrate at respective longitudinal locations, each electrode in the plurality having an electrical resistance sufficient to conduct current laterally along the substrate. The cylindrical structure can include at least one substrate portion extending longitudinally between the adjacent electrodes in the plurality, each substrate portion having an electrical resistance sufficient to conduct current longitudinally between the adjacent electrodes and resistively heat the substrate portion in response to the current conducted there-through. The cylindrical structure can include herbal extract(s) of Embodiments 68-70 disposed on each substrate portion and configured to volatilize into a gas or vapor or to become entrained as an aerosol in air in response to the resistive heating of the substrate portion and an optional flow of air through the cylindrical structure. 
     STATEMENTS 
     1. An herbal extract delivery system comprising: 
     a coated substrate with one or more coating layers, the one or more coating layers including one or more herbal extracts; and 
     a heating element for heating the coated substrate to a temperature to volatize or entrain the one or more herbal extracts on the one or more coating layers into one or more vapors or aerosols inhalable by a user. 
     2. An herbal extract delivery system of statement 1 further comprising multiple coating layers, each layer being a different herbal extract. 
     3. An herbal extract delivery system of statement 1 further comprising a control element for the heating element that controls the time and temperature of heating. 
     4. An herbal extract delivery system of statement 2 further comprising a control element for the heating element that controls the time and temperature of heating. 
     5. An herbal extract delivery system of statement 3 further comprising multiple coating layers and an arrangement of the control element to volatilize sequentially the multiple layers of herbal extracts. 
     6. An herbal extract delivery system of statement 4 further comprising multiple coating layers and an arrangement of the control element to volatilize sequentially the multiple layers of herbal extracts. 
     7. An herbal extract delivery system of statement 2 further comprising overlapping layers in which the layers are ordered by volatilization temperature, the herbal extract with the lowest volatilization temperature being the top layer and the herbal extract with the highest volatilization temperature being the bottom layer adjacent to the substrate.
 
8. An herbal extract delivery system of statement 3 further comprising overlapping layers in which the layers are ordered by volatilization temperature, the herbal extract with the lowest volatilization temperature being the top layer and the herbal extract with the highest volatilization temperature being the bottom layer adjacent to the substrate.
 
9. An herbal extract delivery system of statement 4 further comprising overlapping layers in which the layers are ordered by volatilization temperature, the herbal extract with the lowest volatilization temperature being the top layer and the herbal extract with the highest volatilization temperature being the bottom layer adjacent to the substrate.
 
10. An herbal extract delivery system of statement 5 further comprising overlapping layers in which the layers are ordered by volatilization temperature, the herbal extract with the lowest volatilization temperature being the top layer and the herbal extract with the highest volatilization temperature being the bottom layer adjacent to the substrate.
 
11. An herbal extract delivery system of statement 6 further comprising overlapping layers in which the layers are ordered by volatilization temperature, the herbal extract with the lowest volatilization temperature being the top layer and the herbal extract with the highest volatilization temperature being the bottom layer adjacent to the substrate.
 
12. An herbal extract delivery system of statement 2 further comprising segregated layers of herbal extracts having a coterminous arrangement such that the layers are free from overlap.
 
13. An herbal extract delivery system of statement 3 further comprising segregated layers of herbal extracts having a coterminous arrangement such that the layers are free from overlap.
 
14. An herbal extract delivery system of statement 4 further comprising segregated layers of herbal extracts having a coterminous arrangement such that the layers are free from overlap.
 
15. An herbal extract delivery system of statement 5 further comprising segregated layers of herbal extracts having a coterminous arrangement such that the layers are free from overlap.
 
16. An herbal extract delivery system of statement 6 further comprising segregated layers of herbal extracts having a coterminous arrangement such that the layers are free from overlap.
 
17. An herbal extract delivery system of statement 1 further comprising herbal extracts of herbaceous plants selected from the group consisting of damiana, blue lotus, mullein, lobelia, peppermint, spearmint, catnip, thyme, sage, wild dagga, lavender, rosemary,  Salvia divinorum , basil, lemon balm, hops, yerba mate,  Calea zacatechichi , chamomile, ashwagandha  eucalyptus , passion flower, St John&#39;s wart,  valerian, astragalus, Avena sativa , kinnikinnick, cacao, chago, cinnamon, nutmeg, mace, cordyceps, Don Quai, Gotu  Kola , ginger root,  ginseng , green tea,  kava, maca , moringa leaf, mullein, sacred pink lotus, red raspberry,  rhodiola, rooibos , tong kat ali, vanilla, yohimbine, garlic, turmeric, nutmeg, capsaicin, rosemary,  cannabis , coniferous trees, yew bush, willow tree, aspen tree, blood root, opium poppy,  Atropa belladonna , strychnine,  vinca rosea , coffee plant, cacao tree and beans (chocolate), coca plant (cocaine), nicotinaa  tabacum, Camelia sinensis , monkshood, castor oil, henbane, calabar bean,  digitalis  sp, autumn  crocus , peyote,  amanita , orange, lemon, and any other known herbaceous plants which produce known agents having useful medicinal, pharmacological, physiological, beneficial, sensory or other perceived measurable effects on humans.
 
18. An herbal extract delivery system of statement 2 further comprising herbal extracts of herbaceous plants selected from the group consisting of damiana, blue lotus, mullein, lobelia, peppermint, spearmint, catnip, thyme, sage, wild dagga, lavender, rosemary,  Salvia divinorum , basil, lemon balm, hops, yerba mate,  Calea zacatechichi , chamomile, ashwagandha  eucalyptus , passion flower, St John&#39;s wart,  valerian, astragalus, Avena sativa , kinnikinnick, cacao, chago, cinnamon, nutmeg, mace, cordyceps, Don Quai, Gotu  Kola , ginger root,  ginseng , green tea,  kava, maca , moringa leaf, mullein, sacred pink lotus, red raspberry,  rhodiola, rooibos , tong kat ali, vanilla, yohimbine, garlic, turmeric, nutmeg, capsaicin, rosemary,  cannabis , coniferous trees, yew bush, willow tree, aspen tree, blood root, opium poppy,  Atropa belladonna , strychnine, vinca rosea, coffee plant, cacao tree and beans (chocolate), coca plant (cocaine), nicotinaa  tabacum, Camelia sinensis , monkshood, castor oil, henbane, calabar bean,  digitalis  sp, autumn  crocus , peyote,  amanita , orange, lemon, and any other known herbaceous plants which produce known agents having useful medicinal, pharmacological, physiological, beneficial, sensory or other perceived measurable effects on humans.
 
19. An herbal extract delivery system of statement 7 further comprising herbal extracts of herbaceous plants selected from the group consisting of damiana, blue lotus, mullein, lobelia, peppermint, spearmint, catnip, thyme, sage, wild dagga, lavender, rosemary,  Salvia divinorum , basil, lemon balm, hops, yerba mate,  Calea zacatechichi , chamomile, ashwagandha  eucalyptus , passion flower, St John&#39;s wart,  valerian, astragalus, Avena sativa , kinnikinnick, cacao, chago, cinnamon, nutmeg, mace, cordyceps, Don Quai, Gotu  Kola , ginger root,  ginseng , green tea,  kava, maca , moringa leaf, mullein, sacred pink lotus, red raspberry,  rhodiola, rooibos , tong kat ali, vanilla, yohimbine, garlic, turmeric, nutmeg, capsaicin, rosemary,  cannabis , coniferous trees, yew bush, willow tree, aspen tree, blood root, opium poppy,  Atropa belladonna , strychnine,  vinca rosea , coffee plant, cacao tree and beans (chocolate), coca plant (cocaine), nicotinaa  tabacum, Camelia sinensis , monkshood, castor oil, henbane, calabar bean,  digitalis  sp, autumn  crocus , peyote,  amanita , orange, lemon, and any other known herbaceous plants which produce known agents having useful medicinal, pharmacological, physiological, beneficial, sensory or other perceived measurable effects on humans.
 
20. An herbal extract delivery system of statement 12 further comprising herbal extracts of herbaceous plants selected from the group consisting of damiana, blue lotus, mullein, lobelia, peppermint, spearmint, catnip, thyme, sage, wild dagga, lavender, rosemary,  Salvia divinorum , basil, lemon balm, hops, yerba mate,  Calea zacatechichi , chamomile, ashwagandha  eucalyptus , passion flower, St John&#39;s wart,  valerian, astragalus, Avena sativa , kinnikinnick, cacao, chago, cinnamon, nutmeg, mace, cordyceps, Don Quai, Gotu  Kola , ginger root,  ginseng , green tea,  kava, maca , moringa leaf, mullein, sacred pink lotus, red raspberry,  rhodiola, rooibos , tong kat ali, vanilla, yohimbine, garlic, turmeric, nutmeg, capsaicin, rosemary,  cannabis , coniferous trees, yew bush, willow tree, aspen tree, blood root, opium poppy,  Atropa belladonna , strychnine, vinca rosea, coffee plant, cacao tree and beans (chocolate), coca plant (cocaine), nicotinaa  tabacum, Camelia sinensis , monkshood, castor oil, henbane, calabar bean,  digitalis  sp, autumn  crocus , peyote,  amanita , orange, lemon, and any other known herbaceous plants which produce known agents having useful medicinal, pharmacological, physiological, beneficial, sensory or other perceived measurable effects on humans.
 
21. An herbal extract delivery product comprising: a substrate coated with one or more layers of one or more herbal extracts of one or more herbaceous plants.
 
22. An herbal extract delivery product of statement 21 further comprising a heating element associated with the substrate, the heating element being capable of heating the substrate in a controlled fashion to a selected temperature.
 
23. An herbal extract delivery product of statement 21 further comprising multiple overlapping layers of individual herbal extracts on the substrate.
 
24. An herbal extract delivery product of statement 22 further comprising multiple overlapping layers of individual herbal extracts on the substrate.
 
25. An herbal extract delivery product of statement 23 further comprising an arrangement of the overlapping layers in which the arrangement orders the layers according to the volatilization temperatures of the herbal extracts, the herbal extract with the lowest volatilization temperature being the top layer and the herbal extract with the highest volatilization temperature being the bottom layer adjacent to the substrate.
 
26. An herbal extract delivery product of statement 24 further comprising an arrangement of the overlapping layers in which the arrangement orders the layers according to the volatilization temperatures of the herbal extracts, the herbal extract with the lowest volatilization temperature being the top layer and the herbal extract with the highest volatilization temperature being the bottom layer adjacent to the substrate.
 
27. An herbal extract delivery product of statement 21 further comprising multiple segregated layers of individual herbal extracts.
 
28. An herbal extract delivery product of statement 22 further comprising multiple segregated layers of individual herbal extracts.
 
29. An herbal extract delivery product of statement 27 wherein the segregated layers of herbal extracts are arranged sequentially on the substrate.
 
30. An herbal extract delivery product of statement 28 wherein the segregated layers of herbal extracts are arranged sequentially on the substrate.
 
31. An herbal extract delivery product of statement 23 wherein the herbal extract of one layer differs from the herbal extracts on all other layers.
 
32. An herbal extract delivery product of statement 27 wherein the herbal extract of one layer differs from the herbal extracts on all other layers.
 
33. An herbal extract delivery product of statement 21 further comprising herbal thermal extracts of herbaceous plants selected from the group consisting of damiana, blue lotus, mullein, lobelia, peppermint, spearmint, catnip, thyme, sage, wild dagga, lavender, rosemary,  Salvia divinorum , basil, lemon balm, hops, yerba mate,  Calea zacatechichi , chamomile, ashwagandha  eucalyptus , passion flower, St John&#39;s wart,  valerian, astragalus, Avena sativa , kinnikinnick, cacao, chago, cinnamon, nutmeg, mace, cordyceps, Don Quai, Gotu  Kola , ginger root,  ginseng , green tea,  kava, maca , moringa leaf, mullein, sacred pink lotus, red raspberry,  rhodiola, rooibos , tong kat ali, vanilla, yohimbine, garlic, turmeric, nutmeg, capsaicin, rosemary,  cannabis , coniferous trees, yew bush, willow tree, aspen tree, blood root, opium poppy,  Atropa belladonna , strychnine,  vinca rosea , coffee plant, cacao tree and beans (chocolate), coca plant (cocaine), nicotinaa  tabacum, Camelia sinensis , monkshood, castor oil, henbane, calabar bean,  digitalis  sp, autumn  crocus , peyote,  amanita , orange, lemon, and any other known herbaceous plants which produce known agents having useful medicinal, pharmacological, physiological, beneficial, sensory or other perceived measurable effects on humans.
 
34. An herbal extract delivery product of statement 23 further comprising herbal thermal extracts of herbaceous plants selected from the group consisting of damiana, blue lotus, mullein, lobelia, peppermint, spearmint, catnip, thyme, sage, wild dagga, lavender, rosemary,  Salvia divinorum , basil, lemon balm, hops, yerba mate,  Calea zacatechichi , chamomile, ashwagandha  eucalyptus , passion flower, St John&#39;s wart,  valerian, astragalus, Avena sativa , kinnikinnick, cacao, chago, cinnamon, nutmeg, mace, cordyceps, Don Quai, Gotu  Kola , ginger root,  ginseng , green tea,  kava, maca , moringa leaf, mullein, sacred pink lotus, red raspberry,  rhodiola, rooibos , tong kat ali, vanilla, yohimbine, garlic, turmeric, nutmeg, capsaicin, rosemary,  cannabis , coniferous trees, yew bush, willow tree, aspen tree, blood root, opium poppy,  Atropa belladonna , strychnine,  vinca rosea , coffee plant, cacao tree and beans (chocolate), coca plant (cocaine), nicotinaa  tabacum, Camelia sinensis , monkshood, castor oil, henbane, calabar bean,  digitalis  sp, autumn  crocus , peyote,  amanita , orange, lemon, and any other known herbaceous plants which produce known agents having useful medicinal, pharmacological, physiological, beneficial, sensory or other perceived measurable effects on humans.
 
35. An herbal extract delivery product of statement 27 further comprising herbal thermal extracts of herbaceous plants selected from the group consisting of damiana, blue lotus, mullein, lobelia, peppermint, spearmint, catnip, thyme, sage, wild dagga, lavender, rosemary,  Salvia divinorum , basil, lemon balm, hops, yerba mate,  Calea zacatechichi , chamomile, ashwagandha  eucalyptus , passion flower, St John&#39;s wart,  valerian, astragalus, Avena sativa , kinnikinnick, cacao, chago, cinnamon, nutmeg, mace, cordyceps, Don Quai, Gotu  Kola , ginger root,  ginseng , green tea,  kava, maca , moringa leaf, mullein, sacred pink lotus, red raspberry,  rhodiola, rooibos , tong kat ali, vanilla, yohimbine, garlic, turmeric, nutmeg, capsaicin, rosemary,  cannabis , coniferous trees, yew bush, willow tree, aspen tree, blood root, opium poppy,  Atropa belladonna , strychnine,  vinca rosea , coffee plant, cacao tree and beans (chocolate), coca plant (cocaine), nicotinaa  tabacum, Camelia sinensis , monkshood, castor oil, henbane, calabar bean,  digitalis  sp, autumn  crocus , peyote,  amanita , orange, lemon, and any other known herbaceous plants which produce known agents having useful medicinal, pharmacological, physiological, beneficial, sensory or other perceived measurable effects on humans.
 
36. An herbal extract delivery product of statement 21, comprising:
 
     A cylindrical structure extending in a longitudinal direction and formed from a substrate of an electrically conductive material, the cylindrical structure comprising:
         At least a first set of electrodes extending longitudinally and laterally on the substrate, the at least first set of electrodes having an electrical resistance sufficient to conduct current laterally along the substrate;   An at least first substrate portion coterminous with the at least first set of electrodes, the first substrate portion having an electrical resistance high enough to conduct current from the first set of electrodes and resistively heat the first substrate portion in response to the current conducted there through, and   At least a first dose of an herbal extract disposed on the first substrate portion and configured to volatilize or entrain into a gas or aerosol in response to the resistive heating of the first substrate portion.
 
37. An herbal extract delivery product of statement 36 wherein multiple herbal l extracts are present and the substrate and extracts are arranged as overlapping layers in which the arrangement orders the layers according to the volatilization temperatures of the herbal extracts, the herbal extract with the lowest volatilization temperature being the top layer and the herbal extract with the highest volatilization temperature being the bottom layer adjacent to the substrate.
 
38. An herbal extract delivery product of statement 36 wherein multiple herbal extracts are present and the substrate and extracts are arranged as multiple segregated layers of individual herbal extracts distributed sequentially on the substrate.
 
39. An apparatus, comprising:
       

     A cylindrical structure extending in a longitudinal direction and formed from a substrate of an electrically conductive material, the cylindrical structure comprising:
         A plurality of electrodes extending laterally on the substrate at respective longitudinal locations, each electrode in the plurality having an electrical resistance sufficient to conduct current laterally along the substrate;   at least one substrate portion extending longitudinally between the adjacent electrodes in the plurality, each substrate portion having an electrical resistance sufficient to conduct current longitudinally between the adjacent electrodes and resistively heat the substrate portion in response to the current conducted there through; and   At least one herbal extract disposed on at least one substrate portion and configured to volatilize or entrain into a vapor or aerosol in response to the resistive heating of the substrate portion.
 
40. An apparatus of statement 39 wherein multiple herbal extracts are present and the substrate and extracts are arranged as overlapping layers in which the arrangement orders the layers according to the volatilization temperatures of the herbal extracts, the herbal extract with the lowest volatilization temperature being the top layer and the herbal extract with the highest volatilization temperature being the bottom layer adjacent to the substrate.
 
41. An apparatus of statement 39 wherein multiple herbal extracts are present and the substrate and the extracts are arranged as multiple segregated layers of individual herbal extracts distributed sequentially on the substrate.
 
42. A method of purifying at least one or more herbal extracts from one or more medicinal herbs, the method comprising:
       

     Heating an appropriate herbaceous plant part to a first temperature to volatilize the herbal extract into a first vapor; and 
     Condensing the first vapor onto a substrate to form a first coating or the herbal extract. 
     43. A method of statement 42 further comprising sequentially heating appropriate multiple herbaceous plant parts to volatilize sequentially multiple herbal extracts and condensing sequentially the multiple vapors onto a substrate to form sequential layers of herbal extracts on the substrate.
 
44. A method of making An herbal extract delivery cartridge, the method comprising:
 
     Heating an appropriate herbaceous plant part to a temperature to volatize an herbal extract into a vapor; 
     Condensing the vapor onto a substrate to form a coating of herbal extract on the substrate; and 
     Converting the coated substrate into a three-dimensional structure configured for use as An herbal extract delivery cartridge. 
     45. A method according to statement 44 further comprising: 
     Providing a substrate that is a sheet of conductive material, the sheet extending in longitudinal and lateral dimensions, the sheet having at least one substrate portion extending longitudinally between a pair of adjacent contact portions; 
     Depositing at least one herbal extract on the substrate portion, the herbal extract configured to volatilize into a vapor in response to resistive heating of the respective substrate portion. 
     46. A method of statement 45 comprising converting the sheet into a cylindrical structure. 
     47. A method of statement 45 further comprising depositing as overlapping layers a multiplicity of herbal extracts. 
     48. A method of statement 45 further comprising 
     Sequentially volatilizing herbal extracts from a multiplicity of herbaceous plants into vapors, 
     Sequentially depositing the herbal extract vapors on a moving cooling belt to form solid substances of the herbal extracts on the belt, 
     Sequentially stripping the solid substances rom the cooling belt and heating the stripped solid substances to form liquid herbal extracts, 
     Sequentially transferring the liquid herbal t extracts into a heated container, 
     Sequentially depositing the liquid herbal extracts from the heated container to the sheet of conductive material that is optionally cooled, 
     Forming uniform layers of the deposited herbal extracts on the sheet. 
     49. A method of statement 48 further comprising forming overlapping layers of the deposited herbal extracts. 
     50. A method of statement 48 further comprising forming sequential layers of the deposited herbal extracts. 
     51. A method of statement 42 further comprising herbal extracts of herbaceous plants selected from the group consisting of damiana, blue lotus, mullein, lobelia, peppermint, spearmint, catnip, thyme, sage, wild dagga, lavender, rosemary,  Salvia divinorum , basil, lemon balm, hops, yerba mate,  Calea zacatechichi , chamomile, ashwagandha  eucalyptus , passion flower, St John&#39;s wart,  valerian, astragalus, Avena sativa , kinnikinnick, cacao, chago, cinnamon, nutmeg, mace, cordyceps, Don Quai, Gotu  Kola , ginger root,  ginseng , green tea,  kava, maca , moringa leaf, mullein, sacred pink lotus, red raspberry,  rhodiola, rooibos , tong kat ali, vanilla, yohimbine, garlic, turmeric, nutmeg, capsaicin, rosemary,  cannabis , coniferous trees, yew bush, willow tree, aspen tree, blood root, opium poppy,  Atropa belladonna , strychnine,  Vinca rosea , coffee plant, cacao tree and beans (chocolate), coca plant (cocaine), nicotinaa  tabacum, Camelia sinensis , monkshood, castor oil, henbane, calabar bean,  digitalis  sp, autumn  crocus , peyote,  amanita , orange, lemon, and any other known herbaceous plants which produce known agents having useful medicinal, pharmacological, physiological, beneficial, sensory or other perceived measurable effects on humans.
 
52. A method of statement 44 further comprising herbal extracts of herbaceous plants selected from the group consisting of damiana, blue lotus, mullein, lobelia, peppermint, spearmint, catnip, thyme, sage, wild dagga, lavender, rosemary,  Salvia divinorum , basil, lemon balm, hops, yerba mate,  Calea zacatechichi , chamomile, ashwagandha  eucalyptus , passion flower, St John&#39;s wart,  valerian, astragalus, Avena sativa , kinnikinnick, cacao, chago, cinnamon, nutmeg, mace, cordyceps, Don Quai, Gotu  Kola , ginger root,  ginseng , green tea,  kava, maca , moringa leaf, mullein, sacred pink lotus, red raspberry,  rhodiola, rooibos , tong kat ali, vanilla, yohimbine, garlic, turmeric, nutmeg, capsaicin, rosemary,  cannabis , coniferous trees, yew bush, willow tree, aspen tree, blood root, opium poppy,  Atropa belladonna , strychnine,  Vinca rosea , coffee plant, cacao tree and beans (chocolate), coca plant (cocaine), nicotinaa  tabacum, Camelia sinensis , monkshood, castor oil, henbane, calabar bean,  digitalis  sp, autumn  crocus , peyote,  amanita , orange, lemon, and any other known herbaceous plants which produce known agents having useful medicinal, pharmacological, physiological, beneficial, sensory or other perceived measurable effects on humans.
 
53. A method for producing a substrate coated with one or more herbal extracts, comprising
         a. Comminuting herbaceous plant material to produce particulate material   b. Extracting the particulate plant material with a solvent in which the herbal extract is soluble to produce a solution;   c. Concentrating the solution to produce a concentrate;   d. Depositing the concentrate on the substrate; and,   e. Evaporating the solvent from the concentrate to produce a coating of the herbal extract on the substrate;   f. Optionally repeating steps a-e to produce multiple layers of herbal extracts on the substrate.
 
54. A method according to statement 53 further comprising preforming steps a-e on multiple different herbaceous plant materials to product multiple layers of herbal extracts on the substrate.
 
55. A method of statement 54 further comprising forming overlapping layers of the deposited herbal extracts.
 
56. A method of statement 54 further comprising forming sequential layers of the deposited herbal extracts.
 
57. A method of statement 53 further comprising herbal extracts of herbaceous plants selected from the group consisting of damiana, blue lotus, mullein, lobelia, peppermint, spearmint, catnip, thyme, sage, wild dagga, lavender, rosemary,  Salvia divinorum , basil, lemon balm, hops, yerba mate,  Calea zacatechichi , chamomile, ashwagandha  eucalyptus , passion flower, St John&#39;s wart,  valerian, astragalus, Avena sativa , kinnikinnick, cacao, chago, cinnamon, nutmeg, mace, cordyceps, Don Quai, Gotu  Kola , ginger root,  ginseng , green tea,  kava, maca , moringa leaf, mullein, sacred pink lotus, red raspberry,  rhodiola, rooibos , tong kat ali, vanilla, yohimbine, garlic, turmeric, nutmeg, capsaicin, rosemary,  cannabis , coniferous trees, yew bush, willow tree, aspen tree, blood root, opium poppy,  Atropa belladonna , strychnine,  Vinca rosea , coffee plant, cacao tree and beans (chocolate), coca plant (cocaine), nicotinaa  tabacum, Camelia sinensis , monkshood, castor oil, henbane, calabar bean,  digitalis  sp, autumn  crocus , peyote,  amanita , orange, lemon, and any other known herbaceous plants which produce known agents having useful medicinal, pharmacological, physiological, beneficial, sensory or other perceived measurable effects on humans.
       

     Miscellaneous Characterizations 
     The foregoing detailed description includes references to the accompanying drawings, which form a part of the detailed description. The drawings show, by way of illustration, specific embodiments in which the invention can be practiced. These embodiments are also referred to herein as “examples.” Such examples can include elements in addition to those shown or described. However, the present inventor also contemplates examples in which only those elements shown or described are provided. Moreover, the present inventor also contemplates examples using any combination or permutation of those elements shown or described (or one or more aspects thereof), either with respect to a particular example (or one or more aspects thereof), or with respect to other examples (or one or more aspects thereof) shown or described herein. 
     All publications, patents, and patent documents referred to in this document are incorporated by reference herein in their entirety, as though individually incorporated by reference. In the event of inconsistent usages between this document and those documents so incorporated by reference, the usage in the incorporated reference(s) should be considered supplementary to that of this document; for irreconcilable inconsistencies, the usage in this document controls. 
     In this document, the terms “a” or “an” are used, as is common in patent documents, to include one or more than one, independent of any other instances or usages of “at least one” or “one or more.” In this document, the term “or” is used to refer to a nonexclusive or, such that “A or B” includes “A but not B,” “B but not A,” and “A and B,” unless otherwise indicated. In this document, the terms “including” and “in which” are used as the plain-English equivalents of the respective terms “comprising” and “wherein.” Also, in the following claims, the terms “including” and “comprising” are open-ended, that is, a system, device, article, or process that includes elements in addition to those listed after such a term in a claim are still deemed to fall within the scope of that claim. Moreover, in the following claims, the terms “first,” “second,” and “third,” etc. are used merely as labels, and are not intended to impose numerical requirements on their objects. 
     The foregoing description is intended to be illustrative, and not restrictive. For example, the above-described examples, statements and the embodiments (or one or more aspects thereof) may be used in combination with each other. Other embodiments can be used, such as by one of ordinary skill in the art upon reviewing the above description. The Abstract is provided to allow the reader to quickly ascertain the nature of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. Also, in the above Detailed Description, various features may be grouped together to streamline the disclosure. This should not be interpreted as intending that an unclaimed disclosed feature is essential to any claim. Rather, inventive subject matter may lie in less than all features of a particular disclosed embodiment. Thus, the following claims are hereby incorporated into the Detailed Description, with each claim standing on its own as a separate embodiment, and it is contemplated that such embodiments can be combined with each other in various combinations or permutations. The scope of the invention should be determined with reference to the appended claims, along with the full scope of equivalents to which such claims are entitled.