Patent Publication Number: US-2022211359-A1

Title: Wire gripping device

Description:
TECHNICAL FIELD 
     The disclosure relates to medical devices. 
     BACKGROUND 
     Some medical devices include a wire, such as a guidewire or a push wire. During a medical procedure, a clinician may control movement of the wire, such as by applying a distal pushing force and/or a torqueing motion to a proximal portion of the wire to navigate a distal portion. The wire may be relatively thin and can also include a hydrophilic coating, both of which may make it difficult for a clinician to manually grip, e.g., between fingers. A wire gripper, also referred to as a wire torquer in some cases, may attached to the wire to enable a clinician to better control the wire, e.g., to apply an adequate pushing, pulling, and/or twisting/torqueing force to the wire. 
     SUMMARY 
     The present disclosure describes a wire gripping device including a locking cam configured to be operable by one hand of a user, such as a clinician, to alternately grip and/or release a wire, or other elongate shaft such as a tube or hypotube, of a medical device. The wire gripping device includes a one handed locking cam and a collet. The wire gripping device may be small, light, and enable one handed operation of the wire gripping device, e.g., pushing, pulling, torqueing, and repositioning and regripping of the wire. For example, the wire gripping device may enable a user to push a cam of the wire gripping device to cause the wire gripping device to grip the wire, push, pull, and or torque the wire using the wire gripping device, and push the cam to release the wire, reposition the wire gripping device on the wire and push a cam to regrip the wire for subsequent pushing, pulling, and/or torqueing, all with one hand. 
     Clause 1: In some examples, a device includes a collet defining a collet lumen, the collet lumen configured to receive a medical device wire or shaft; a collet sleeve configured to at least partially house the collet, wherein the collet sleeve defines a collet sleeve lumen configured to receive the medical device wire or shaft, wherein the collet sleeve comprises a flange; and a cam configured to at least partially house the collet sleeve, wherein the cam defines a cam lumen configured to receive the medical device wire or shaft; and a housing includes a proximal portion configured to at least partially house the collet and collet sleeve; and a distal portion, wherein the cam is rotatably attached to the distal portion, wherein the cam is configured to move the collet sleeve and collet towards the proximal portion of the housing upon rotation of the cam relative to the housing from a release position to a grip position, wherein the cam is configured to enable the collet sleeve and collet to move towards the distal portion of the housing upon rotation of the cam relative to the housing from the grip position to the release position. 
     Clause 2: In some examples of the device of clause 1, the medical device wire or shaft comprises a guidewire, a guide extension catheter wire, a wire coupled to an implant, or a tube or hypotube. 
     Clause 3: In some examples of the device of any of clauses 1 or 2, a proximal end of the collet defines one or more slots, wherein the one or more slots are configured to compress radially inwards in response to rotation of the cam relative to the housing from the release position to the grip position. 
     Clause 4: In some examples of the device of any of any of clauses 1-3, the collet comprises one or more tabs extending radially outwards at a proximal end of the collet, wherein a proximal surface of each tab tapers towards the proximal end of the collet. 
     Clause 5: In some examples of the device of any of clauses 1-4, an inner surface of the proximal portion of the housing is tapers towards the proximal end of the housing and is configured to engage the proximal surfaces of the one or more tabs. 
     Clause 6: In some examples of the device of clause 5, the collet sleeve is configured to move the collet towards the proximal portion of the housing upon being pushed by the cam, thereby forcing the proximal surfaces of the one or more tabs to engage the inner surface of the proximal portion of the housing, wherein the inner surface of the proximal portion of the housing is configured to resist movement of the collet and cause the one or more tabs to apply a radially inward force to compress the collet. 
     Clause 7: In some examples of the device of any of clauses 5 or 6, the collet is biased radially outwards to enable the proximal surfaces of the one or more tabs to engage the inner surface of the proximal portion of housing and move the collet and collet sleeve in a distal direction relative to the housing upon rotation of the cam from the grip position to the release position. 
     Clause 8: In some examples of the device of clause 7, upon rotation of the cam from the grip position to the release position, a diameter of the collet lumen is configured to increase and thereby decrease a grip force on the device. 
     Clause 9: In some examples of the device of any of clauses 1-8, rotation of the cam from the release position to the grip position is configured to push compress the collet, and wherein the collet is configured to decrease a diameter of the collet lumen and increase a grip force on the medical device wire or shaft upon compression of the collet. 
     Clause 10: In some examples of the device of any of clauses 1-9, the cam comprises one or more posts, the one or more posts configured to be rotatably attached within one or more apertures of the housing, wherein the cam is configured to push the housing in a distal direction via the one or more posts while pushing the collet sleeve in a proximal direction via the flange. 
     Clause 11: In some examples of the device of any of clauses 1-10, the cam is configured to apply a radial force compressing the collet, via the one or more tabs, in response to rotation of the cam relative to the housing. 
     Clause 12: In some examples of the device of any of clauses 1-11, the cam is configured to remain in the grip position until a force greater than a predetermined threshold force is applied to the cam in a release direction. 
     Clause 13: In some examples, a method includes introducing a medical device wire or shaft into a device lumen of a device, wherein the device comprises: a collet defining a collet lumen; a collet sleeve configured to at least partially house the collet, wherein the collet sleeve defines a collet sleeve lumen, wherein the collet sleeve comprises a flange; and a cam configured to at least partially house the collet sleeve, wherein the cam defines a cam lumen; and a housing includes a proximal portion configured to at least partially house the collet and collet sleeve; and a distal portion, wherein the cam is rotatably attached to the distal portion, wherein the device lumen is at least partially defined by the collet lumen, the collet sleeve lumen, and the cam lumen; rotating the cam relative to the housing from release position towards a grip position, wherein the cam is configured to move the collet sleeve and collet towards the proximal portion of the housing upon rotation of the cam relative to the housing from the release position to the grip position, and wherein the cam is configured to enable the collet sleeve and collet to move towards the distal portion of the housing upon rotation of the cam relative to the housing from the grip position to the release position. 
     Clause 14: In some examples of the method of clause 13, the medical device wire or shaft comprises a guidewire, a guide extension catheter wire, a wire coupled to an implant, or a tube or hypotube. 
     Clause 15: In some examples of the method of any of clauses 13 or 14, a proximal end of the collet defines one or more slots, wherein rotating the cam from the release position towards the grip position comprises compressing the one or more slots radially inwards. 
     Clause 16: In some examples of the method of any of clauses 13-15, the method further includes rotating the cam from the grip position towards the release position; and repositioning the device along the medical device wire or shaft. 
     Clause 17: In some examples of the method of any of clauses 13-16, the method further includes locking the cam in a grip position until a force greater than a predetermined threshold force is applied to the cam in a release direction. 
     Clause 18: In some examples, a medical device includes a collet defining a collet lumen, the collet lumen configured to receive a medical device wire or shaft; a collet sleeve configured to at least partially house the collet, wherein the collet sleeve defines a sleeve lumen configured to receive the medical device wire or shaft, wherein the collet sleeve comprises a flange; and a cam configured to at least partially house the collet sleeve, wherein the cam defines a cam lumen configured to receive the medical device wire or shaft; and a housing includes a proximal portion configured to at least partially house the collet and collet sleeve; and a distal portion, wherein the cam is rotatably attached to the distal portion, wherein the cam is configured to increase a push force against the flange upon rotation of the cam relative to the housing from a release position to a grip position and thereby move the collet sleeve and collet towards the proximal portion of the housing, wherein the cam is configured to move the collet sleeve and collet towards the proximal portion of the housing upon rotation of the cam relative to the housing from a release position to a grip position, wherein the cam is configured to enable the collet sleeve and collet to move towards the distal portion of the housing upon rotation of the cam relative to the housing from the grip position to the release position, wherein rotation of the cam from the release position to the grip position is configured to push compress the collet, and wherein the collet is configured to decrease a diameter of the collet lumen and increase a grip force on the medical device wire or shaft upon compression of the collet. 
     Clause 19: In some examples of the medical device of clause 18, upon rotation of the cam from the grip position to the release position, the diameter of the collet lumen is configured to increase to decrease the grip force on the medical device. 
     Clause 20: In some examples of the medical device of any of clauses 18 or 19, the cam is configured to remain in the grip position until a force greater than a predetermined threshold force is applied to the cam in a release direction. 
     The details of one or more examples are set forth in the accompanying drawings and the description below. Other features, objects, and advantages will be apparent from the description and drawings, and from the claims. 
    
    
     
       BRIEF DESCRIPTION OF THE DRAWINGS 
         FIG. 1  is a perspective view illustrating an example wire gripping device. 
         FIG. 2  is cross-sectional view of an example wire gripping device with a cam in a release position. 
         FIG. 3  is a cross-sectional view of an example wire gripping device with a cam in a grip position. 
         FIG. 4  is a perspective view of an example collet of a wire gripping device. 
         FIG. 5  is a perspective view of an example collet in a sleeve of a wire gripping device. 
         FIG. 6  is a perspective view of an example cam housing a collet in a collet sleeve of a wire gripping device. 
         FIG. 7  is a perspective view of an example housing connected to a cam housing a collet in a collet sleeve of a wire gripping device. 
         FIG. 8  is a flow diagram of an example method of using a wire gripping device. 
     
    
    
     DETAILED DESCRIPTION 
     The present disclosure describes wire gripping devices including a locking cam operable by one hand of a user to alternately grip and/or release a wire, or other elongate shaft such as a tube or hypotube, of a medical device. The wire can be, for example, a guidewire, a push wire of a guide extension catheter, a wire coupled to an implant or embolization device (e.g., a coil) or another elongated medical device (e.g. those used in intravascular procedures) that may be gripped and manipulated by a clinician during a medical procedure. 
     The gripping device defines a device lumen configured to receive the medical device wire, e.g., and enable the medical device wire to extend through the entire gripping device from a proximal end to a distal end of the gripping device. The device lumen can be defined by one or more structures of the gripping device, including a collet, a housing, and a collet sleeve. 
     In some examples, the gripping device includes a collet defining a lumen configured to receive the medical device wire, a collet sleeve configured to at least partially house the collet, the collet sleeve defining a collet sleeve lumen configured to receive the medical device wire, and a cam configured to at least partially house the collet sleeve and defining a cam lumen configured to receive the medical device wire. The gripping device may also include a housing that includes a proximal portion configured to at least partially house the collet and collet sleeve and a distal portion to which the cam is rotatably attached. 
     The cam is configured to be rotated relative to the housing from a grip position to a release position and vice versa. In the grip position of the cam, the medical device wire or shaft is secured within the device lumen, e.g., to enable the gripping device and the medical device wire to move as one unit. That is, when the cam is in the grip position, as the gripping device is moved (e.g., pushed or pulled along a longitudinal axis of the medical device wire and/or torqued about the longitudinal axis), the medical device wire moves with the gripping device. In this way, the gripping device provides structure for a user to grip and may facilitate controllable application of axial force, e.g., push and pull along a longitudinal axis of the medical device wire, and torqueing of the medical device wire, e.g., rotation about the longitudinal axis of the medical device wire. For example, a medical device wire or shaft may be relatively thin and/or may include a lubricious coating (e.g., a hydrophilic coating) that may make direct gripping and manipulation of the medical device wire itself by hand relatively difficult. The gripping device may be configured to secure relative to the medical device wire to enable a user to manipulate the guidewire by manipulating of the gripping device. The gripping device may be sized for a user to more comfortably manipulate the medical device wire in comparison to directly gripping the medical device wire. 
     In some examples, the gripping device may enable a user to grip and/or lock the gripping device on the medical device wire, manipulate the medical device wire via the gripping device, and release and reposition the gripping device with one hand. In the release position, the gripping device is configured to move relative to the gripping wire. This can enable a clinician to reposition the gripping device relative to the medical device wire (e.g., to move the gripping device proximally or distally along a longitudinal axis of the medical device wire and/or to change a rotational position of the gripping device relative to the medical device wire) or introduce or remove medical device wire from the device lumen of the gripping device. 
     The cam of the gripping device may be configured to push a flange of the collet sleeve to move the collet sleeve and collet in the proximal direction relative to the cam and the housing when the cam is rotated in the direction of the grip position, e.g., from a release position towards the grip position. The collet may include one or slots that enable the diameter of the collet to be decreased when a radial force is applied via one or more tabs at the distal end of the collet. In some examples, the one or more tabs may be tapered towards the proximal end of the collet and may be configured to engage with inner surfaces of the proximal portion of the housing, e.g., to resist movement of the collet towards in the proximal direction and convert the movement and/or push force from the cam in the proximal direction to movement and/or a force in the radial direction via the tabs to compress the collet lumen and increase a grip force on the medical device wire. In some examples, the collet is configured to be biased radially outwards, e.g., at least partially elastic, and exert an elastic and/or spring force to resist the radial force, such that when the cam is rotated in the direction of the release position, e.g., from the grip position towards the release position, the collet may decompress. Such decompression of the collet decreases the grip force of the collet on the medical device wire or shaft and causes radially outward movement and/or a radially outward directed force on the tabs, which may engage with the inner surfaces of the housing and convert the radially outward movement and/or force to movement and/or a force in the distal direction. 
     In some examples, the wire gripping device may be configured to lock in the grip position and/or in the release position. For example, the cam may be configured to lock or remain in a grip position until a force greater than a predetermined threshold force is applied to the cam in the release direction. 
     The wire gripping device may be small, light, and enable one handed operation of the wire gripping device by a clinician, e.g., pushing, pulling, torqueing, and repositioning and regripping of the wire. For example, the wire gripping device may enable a user to push a cam of the wire gripping device to cause the wire gripping device to grip the wire, push, pull, and or torque the wire using the wire gripping device, and push the cam to release the wire, reposition the wire gripping device on the wire, and push a cam to regrip the wire for subsequent pushing, pulling, and/or torqueing, all with one hand. 
       FIG. 1  is a conceptual perspective view illustrating an example wire or shaft gripping device  100 . In the example shown, wire gripping device  100  includes housing  102 , cam  104 , collet sleeve  106 , and collet  108  (not visible in  FIG. 1 ). Cam  104  is illustrated in a cam position between a release position and a grip position, e.g., between fully releasing and fully gripping medical device wire  110  received within and extending through a device lumen of wire gripping device  100  in the example shown. In some examples, medical device wire  110  is a guidewire. In other examples, medical device wire  110  is a guide extension catheter wire (e.g., a push wire) or a wire connected to an embolization device. In still other examples, medical device wire  110  is any other suitable elongated element or shaft, such as a tube, hypotube, or catheter body, that is part of a medical device or used to facilitate a medical procedure. The elongated element can be, for example, configured to be introduced into a hollow anatomical structure of a patient (e.g., a blood vessel). 
     In the example shown in  FIG. 1 , housing  102  includes a proximal portion  112  configured to house collet sleeve  106 . Housing  102  has any suitable shape. In some examples, proximal portion  112  is substantially cylindrical (e.g., a majority of the proximal portion defines a cylinder-like shape) and has a substantially circular (e.g., circular or nearly circular to the extent permitted by manufacturing tolerances) cross-sectional shape, the cross-section being take in a direction orthogonal to a longitudinal axis of wire gripping device  100 , which runs parallel to medical device wire  110  shown in  FIG. 1 . Other cross-sectional shapes can also be used. 
     Housing  102  also includes a distal portion  114  at a distal end  100 B of wire gripping device  100 . Distal portion  114  is configured to rotatably connect to cam  104 . Distal portion  114  can be integrally formed with and/or separate from and mechanically attached to proximal portion  112 . In the example shown, distal portion  114  comprises two arms  126 ,  128  each including an aperture  116  configured to receive a post  118  of cam  104  and separated from each other and configured to accept cam  104 . Proximal portion  112  at a proximal end  100 A of wire gripping device  100  may be configured to at least partially house a collet  108  and a collet sleeve  106 . Housing  102  may be made of metal, plastic, or any suitable material for providing structure for wire gripping device  100 . 
     Cam  104  includes slot  140  configured to receive collet sleeve  106 . Cam  104  may include posts  118  configured to fit within apertures  116  and enable cam  104  to rotate relative to housing  102 . Cam  104  may be made of metal, plastic, or any suitable material for providing structure to push against both housing  102  and collet sleeve  106 . 
     Collet sleeve  106  is configured to receive and house collet  108  and may be configured to be received by cam  104 . In the example shown in  FIG. 1 , collet sleeve  106  includes flange  122  configured to contact cam  104  and provide structure for cam  104  to push against and thereby move collet sleeve  106  relative to housing  102 . Flange  122  may be integrally formed with and/or separate from and mechanically attached to collet sleeve body  124 . Collet sleeve  106  has any suitable shape. In some examples, collet sleeve  106  is substantially cylindrical having a substantially circular cross-sectional shape, the cross-section being take in a direction orthogonal to the longitudinal axis of wire gripping device  100 . Collet sleeve  106  may be made of metal, plastic, or any suitable material for providing structure for cam  104  to push against to move collet sleeve  106  relative to housing  102 . 
     In the example shown, cam  104  has a length that varies relative to the longitudinal axis of wire gripping device  100  in a circumferential direction C, depending on a position of cam  104  relative to housing  102 . In particular, cam  104  has a length L1 at a first circumferential position, e.g., the release position, and its length increases in the circumferential direction to a length L2 at a second circumferential position, e.g., the grip position. The circumferential direction C can, but need not, extend along an outer perimeter of an imaginary circle. Rather, the circumferential direction C can extend along any curve. Lengths L1 and L2 can be measured, for example, through a center of cam  104  from end to end of cam  104 , along an edge of cam  204  from end to end of cam  104 , or the like, and in a manner consistent with each other. 
     In some examples, cam  104  is configured to move the collet sleeve and/or increase a push force against flange  122  in the proximal direction, e.g., in the axial direction from distal end  100 B to proximal end  100 A. For example, a user may rotate cam  104  in a grip direction relative to housing  102 , e.g., the grip direction being the direction of rotation of cam  104  from a greater cam  104  length L2 to lesser cam  104  length L1 and the same as circumferential direction C in the example shown. When cam  104  is rotated relative to housing  102  in the grip direction, the length of the portion of cam  104  contacting flange  122  and apertures  116  of housing  102  increases and causes the push force against flange  122 . For example, cam  104  is mechanically connected to housing  102  via posts  118 , which are rotatably supported within apertures  116 , and when cam  104  is rotated from a release position with a length L1 to a grip position with a length L2 that is greater than L1, cam  104  pushes housing  102  in a distal direction, e.g., in the axial direction from proximal end  100 A to distal end  100 B, via posts  118 . At the same time, cam  104  pushes collet sleeve  106  in the proximal direction via flange  122 . In other words, rotating cam  104  in the grip direction increases the length of the mechanical structure contacting flange  122  and apertures  116 , namely, cam  104 . Similarly, when cam  104  is rotated in the opposite direction the length of cam  104  in contact between flange  122  and apertures  116  decreases, decreasing the push force in the proximal direction on collet sleeve  106  and the push force in the distal direction on housing  102 . 
     In some examples, cam  104  increases the push force against flange  122  when rotated in the grip direction and causes collet sleeve  106  to move towards the proximal end of housing  102  within housing  102 . Collet  108  may be at least partially housed within collet sleeve  106 , and collet sleeve  106  may be configured to push collet  108  upon being pushed by cam  104 . In some examples, collet  108  may include a lumen configured to receive medical device wire  110 . 
     In some examples, and as illustrated and described below with reference to  FIG. 2 , when cam  104  is rotated in the grip direction, cam  104  is configured to apply a push force in the proximal axial direction (along the longitudinal axis of wire gripping device  100 ) to collet  108  and one or more inner surfaces of housing  102 . Collet  108  and the one or more inner surfaces of housing  102  are configured to convert this push force in the proximal axial direction to a radially inwards force, which may compress collet  108  (e.g., converting the movement of collet  108  in the proximal axial direction to a radially inwards movement). The compression of collet  108  causes a lumen of collet  108  to contact and grip medical device wire or shaft  110 , e.g., collet  108  may increase a grip force on medical device wire  110  when cam  104  is rotated from the release position to the grip position. 
     In some examples, collet  108  may be configured is biased radially outwards, e.g., collet  108  may be at least partially elastic such that collet  108  may push radially outwards in resistance to a radially inwards force. In some examples, when cam  104  is rotated in the opposite direction, e.g., in the release direction or from the grip position towards the release position, collet  108  decompresses via a radially outwards elastic force and/or spring force and may cause movement in the radially outwards direction. Collet  108  and the one or more inner surfaces of housing  102  may then convert the spring force and/or radially outwards movement to a push force in the distal axial direction on collet  108  and/or movement of collet  108  in the distal axial direction. In other words, rotating cam  104  in the release direction may decrease the push force on collet  108  which may decrease a grip force on medical device wire  110 . 
       FIG. 2  is a conceptual cross-sectional view of an example wire gripping device  100  with a cam in a release position, the cross-section being taken in a direction parallel to the longitudinal axis of wire gripping device  100  and through a longitudinal center of gripping device  100 . Housing  102 , cam  104 , collet sleeve  106 , and collet  108  of wire gripping device  100  are shown in  FIG. 2 . 
     In the example shown, cam  104  is illustrated in the release position in which cam  104  is rotated such that the length of cam  104  between posts  118  and flange  122  is L1. In the example shown, cam  104  includes a tapered and or shaped inner surface  160  which may be configured to mate with collet sleeve  106  and thereby lock cam  104  in a grip position and is visible in  FIG. 2  by virtue of cam  104  being in the release position. For example, inner surface  160  may be configured to cause cam  104  to remain in the grip position, e.g., illustrated in  FIG. 3  below, until a force greater than a predetermined threshold force is applied to the cam in the release direction. In other examples, inner surface  160  of cam  104  may or may not be shaped in this manner, and cam  104  may be configured to remain in the grip position until a force greater than a predetermined threshold force is applied to the cam in the release direction. 
     In some examples, the grip position may correspond to the circumferential position, i.e., rotational position, at which the length of cam  104  between posts  118  and flange  122  is a maximum, e.g., L2. In other examples, the grip position may correspond to a different circumferential and/or rotational position of cam  104 . For example, the outer circumferential surface of cam  104  that engages with and/or contacts flange  122  may be flattened such the length L2 is at a circumferential position before cam  104  is rotated all the way to the grip position. In other words, the circumferential and/or rotational position of cam  104  corresponding to length L2 may be between the grip position and the release position, and may be substantially near the grip position, and the length of cam  104  between posts  118  and flange  122  at the circumferential and/or rotational position corresponding to the grip position may be less than L2. As a clinician and/or user rotates cam  104  in the grip direction past the circumferential and/or rotational position corresponding to L2 to the grip position, the length of cam  104  between posts  118  and flange  122  may decrease and the elastic force of collet  108 , as further described below, may cause collet sleeve  106  to move and/or exert a force in the distal direction on cam  104  thereby locking cam  104  in the grip rotational position. For example, the elastic force of collet  108  may cause flange  122  to push against cam  104  in the distal direction such that cam  104  is prevented from rotating in the release direction until a clinician (or other user) applies a force greater than a predetermined threshold force to cam  104  in the release direction, e.g., the release direction being the rotational direction opposite circumferential direction C as illustrated in  FIG. 1 . 
     In some examples, any suitable means for locking cam  104  to remain in the grip position until a force greater than a predetermined threshold force is applied to the cam in the release direction may be used. Similarly, cam  104  may be configured to lock in the release position, e.g., either by a shaped inner surface  170  as illustrated in  FIG. 3 , a flattened outer circumferential surface portion, or any other suitable means. 
     In the example shown, collet  108  is partially housed within collet sleeve  106 . Collet  108  defines one or more slots  140  at one or more positions around a perimeter of collet  108  (referred to herein as circumferential positions although collet  108  may not be circular in cross-section in all examples) and having a length that is less than the entire length of collet  108 , e.g., 10% to 75%, such as 10%, 25%, 50%, or 75% the length of collet  108  in the axial direction. In some examples, each slot  140  may have a width sufficient to allow collet  108  to decompress and contact and grip medical device wire  110 . 
     As shown, collet  108  may include one or more tabs  130 . Tabs  130  may extend radially outwards from another part of collet  108  and in some examples, are located at a proximal portion (e.g., at a proximal end) of collet  108 . In some examples, tabs  130  may include proximal surfaces  134  that taper towards the proximal end of collet  108 , and tabs  130  may include distal surfaces  136  that taper towards the distal end of collet  108 . 
     In the example shown, housing  102  may include one or more inner surfaces  132  that taper towards the proximal end of housing  102 . In the example shown, collet sleeve  106  may include one or more collet sleeve proximal surfaces  138  that taper away from the proximal end of collet sleeve  106 . 
     In some examples, collet sleeve proximal surfaces  138  are configured to engage with distal surfaces  136 , e.g., to push tabs  130  and collet  108  in a proximal axial direction. Inner surfaces  132  may be configured to engage with proximal surfaces  134  of tabs  130 , and to cause and/or convert proximal axial movement and/or at least a portion of proximal axial force into a radially inwards movement and/or force, respectively. For example, when tabs  130  are pushed by collet sleeve  106  via surfaces  138 / 136 , proximal surfaces  134  contact inner surfaces  132  which allow collet  108  to move in the proximal axial direction via proximal surfaces  134  sliding along inner surfaces  132  while forcing tabs  130  radially inwards and thereby exerting a radially inwards force on tabs  130  to compress collet  108 . Slots  140  are configured to allow collet  108  to compress and reduce a diameter of the collet lumen in response to the radially inwards force and/or movement of tabs  130  and increase a grip force on medical device wire  110  disposed with the collet lumen (not shown in  FIG. 2 ). 
     In the example shown, wire or shaft gripping device  100  includes spacer  146 , which may be configured to constrain collet sleeve  106  to movement substantially in the axial direction. 
     In operation, when cam  104  is rotated in the grip direction, cam  104  may push against apertures  116  (not shown in  FIG. 2 ) in the distal axial direction and against flange  122  in the proximal axial direction thereby decreasing space  150  between flange  122  and proximal portion  112  of housing  102  and moving and/or increasing the push force on collet sleeve  106  in the proximal axial direction relative to housing  102 . Collet sleeve  106  may then move and/or increase a push force on collet  108  in the proximal axial direction via engagement and/or contact of collet sleeve proximal surfaces  138  with distal surfaces  136  of tabs  130 . Tabs  130  may then move and/or increase a push force in the proximal axial direction and proximal surfaces  134  may engage with and/or contact inner surfaces  132  to simultaneously move tabs  130  in the proximal axial direction and the radially inwards direction, and/or proximal surfaces  134  may engage with and/or contact inner surfaces  132  to convert at least a portion of the push force on tabs  130  in the proximal axial direction to a force in the radially inwards direction. In response to the radially inwards force and/or movement of tabs  130 , collet  108  may compress the collet lumen and/or increase the grip force on medical device wire  110  disposed within the collet lumen. 
     Similarly, in operation when cam  104  is rotated in the release direction, cam  104  may decrease the push force against apertures  116  (not shown in  FIG. 2 ) in the distal axial direction and against flange  122  in the proximal axial direction, thereby allowing collet sleeve  106  to move in the distal axial direction and/or decrease the push force on tabs  130  in the proximal axial direction. Collet  108  may elastically push back against the radially inwards movement and/or force of tabs  130 , and may cause the collet lumen to decrease the grip force on medical device wire  110  and/or decompress (e.g., expand) and move tabs  130  and collet  108  in the distal axial direction via the engagement of inner surfaces  132  and proximal surfaces  134 . 
       FIG. 3  is a cross-sectional view of an example wire gripping device  100  with a cam in a grip position in which cam  104  is rotated such that the length of cam  104  between posts  118  and flange  122  is L2. As shown in  FIG. 3 , cam  104  includes a tapered and or shaped inner surface  170  which may be configured to mate with collet sleeve  106  and thereby lock cam  104  in the release position and is visible in  FIG. 3  by virtue of cam  104  being in the grip position. 
     In operation, when cam  104  is rotated in the release direction, cam  104  may decrease the push force against apertures  116  (not shown in  FIG. 3 ) in the distal axial direction and against flange  122  in the proximal axial direction, thereby allowing collet sleeve  106  to move in the distal axial direction and/or decrease the push force on tabs  130  in the proximal axial direction. Collet  108  may elastically push back against the radially inwards movement and/or force of tabs  130 , and may cause the collet lumen to decrease the grip force on medical device wire  110  and/or decompress (e.g., expand) and move tabs  130  and collet  108  in the distal axial direction via the engagement of inner surfaces  132  and proximal surfaces  134 . 
       FIGS. 4-7  illustrate example components of a wire gripping device  400  and how they fit together as a progression of adding wire gripping device  400  components starting from collet  408  illustrated in  FIG. 4  to the entire wire gripping device  400  illustrated in  FIG. 7 . 
       FIG. 4  is a perspective view of an example collet  408 , which is an example of collet  108 . Collet  408  includes collet body  402 , one or more tabs  430 , and one or more slots  440 . In the example shown, collet  408  may define a lumen configured to receive a medical device wire. Tabs  430  include proximal surfaces  434  that taper towards the proximal end of collet  408  and may be configured to engage with inner surfaces of a housing. Slots  440  are configured to allow collet  408  to compress in response to the application of a radially inwards force to tabs  430 . 
       FIG. 5  is a perspective view of an example collet  408  partially housed within a collet sleeve  406 , which is an example of collet sleeve  106 . In the example shown, collet sleeve  406  includes flange  422 .  FIG. 6  is a perspective view of an example collet  408  partially housed within a collet sleeve  406  partially housed within a cam  404 , which is an example of cam  104 . In the example shown, cam  404  is near the release position relative to collet sleeve  406 .  FIG. 7  is a perspective view of an example housing  402  connected to cam  404 . Housing  402  is an example of housing  102 . 
       FIG. 8  is a flow diagram of an example method of using a wire gripping device. 
     While  FIG. 8  is described with reference to wire gripping device  100 , in other examples, the method can be used with other similar wire gripping devices, such as wire gripping device  400 . 
     A user may introduce a medical device wire or shaft into a lumen of wire gripping device  100  ( 802 ). For example, a user may rotate cam  104  to the release position and slide wire gripping device  100  onto medical device wire  110  at one of the ends of medical device wire  110 . 
     A user may rotate cam  104  from a release position to a grip position ( 804 ). For example, a user may push on cam  104  to rotate cam  104  relative to housing  102  in the grip direction C as illustrated in  FIG. 1 . In response to the rotation, cam  104  may push collet sleeve  106  towards proximal portion  112  of housing  102  via engaging with and/or contacting flange  122 , and collet sleeve  106  may then push collet  108  towards proximal portion  112  of housing  102  in response to being pushed by cam  104 . In some examples, cam  104  may push collet sleeve  106  in the proximal axial direction via pushing against apertures  116  of housing  102  in the distal axial direction via posts  118  mechanically connected to cam  104  and rotatably housed within apertures  116 . 
     In response to being pushed, collet  108  may move in the proximal axial direction and proximal surfaces  134  of tabs  130  may engage with inner surfaces  132 , which may cause a radially inwards force on tabs  130  proportional to an amount of the pushing of the collet sleeve. In response, collet  108  may compress, via slots  140 , a lumen defined by collet  108  and configured to receive medical device wire  110 , and thereby increase a grip force of collet  108  on medical device wire  110 . 
     In some examples, a user may lock cam  104  in the grip position via rotating cam  104  all the way to the grip position. In some examples, a user may unlock cam  104  by applying a force to cam  104  in the release direction that is greater than a predetermined threshold force. 
     The user may manipulate medical device wire or shaft  110  via wire gripping device  100  and/or  400  ( 806 ). Once in the grip position, wire gripping device  100  may provide the user with a sufficient grip between wire gripping device  100  and medical device wire  110 , and between wire gripping device  100  and a hand of the user. In some examples, the user may manipulate medical device wire  110  by torqueing (e.g., rotating about a central longitudinal axis) medical device wire  110  and/or pushing and pulling medical device wire  110 . In some examples, the user may manipulate medical device wire  110  with wire gripping device  100  in the locked position, or in an unlocked position and gripping medical device wire  110  with a portion of the maximum grip force of wire gripping device  100 ,  400 . 
     The user may rotate cam  104  from a grip position to a release position ( 808 ). For example, the user may push on cam  104  to rotate cam  104  relative to housing  102  in the release direction, e.g., a direction opposite direction C as illustrated in  FIG. 1 . In response to the rotation, cam  104  may reduce a push force on collet sleeve  106  towards proximal portion  112  of housing  102  via flange  122 , and collet sleeve  106  may then reduce a push force against collet  108  towards proximal portion  112  of housing  102  in response to the reduced push force of cam  104 . Collet  108  may then decompress via its radially outwards bias, e.g., its elastic force and/or spring force, and decrease a grip force on medical device wire  110 . In response to the decompression of collet  108 , tabs  130  may exert a radially outwards force on proximal surfaces  134 , which may engage with inner surfaces  132  of housing  102  and cause collet  108  to move in the distal axial direction. Collet  108  may then push against and/or move collet sleeve  106  in the distal axial direction. 
     In some examples, the user may reposition wire gripping device  100  along medical device wire  110  ( 810 ). For example, the user may rotate cam  104  towards the release position, and/or to the release position, allowing collet  108  to decompress and reduce its grip on medical device wire, and/or release from medical device wire  110 , thereby allowing wire gripping device  100  to move and/or slide along medical device wire  110 . In some examples, the user may rotate cam  104  and reposition wire gripping device  100  with the same hand and/or a single hand. In some examples, the user may grip medical device wire  110 , e.g., via rotating cam  104  towards the grip position, manipulate medical device wire  110 , release medical device wire  110 , e.g., via rotating cam  104  towards the release position, and reposition wire gripping device  100  all with a single hand. 
     Various examples of the disclosure have been described. Any combination of the described systems, operations, or functions is contemplated. These and other examples are within the scope of the following claims.