Patent Publication Number: US-2017355933-A1

Title: Cleaning compositions including nuclease enzyme and malodor reduction materials

Description:
FIELD OF THE INVENTION 
     The present disclosure relates to cleaning compositions that include a nuclease enzyme and malodor reduction materials. The present disclosure also relates to methods of making and using such cleaning compositions. The present disclosure also relates to the use of malodor reduction materials. 
     BACKGROUND OF THE INVENTION 
     The laundry detergent formulator is constantly aiming to improve the performance of detergent compositions, particularly on malodorous soils. Nuclease enzymes are useful in providing malodor-reducing benefits. In particular, it is believed that nuclease enzymes can help to loosen and/or release malodorous soils from a target surface. However, some malodors may remain. 
     There is a need for improved cleaning compositions that provide malodor-reducing benefits. 
     SUMMARY OF THE INVENTION 
     The present disclosure relates to a cleaning composition that includes a nuclease enzyme and at least one malodor reduction material. 
     The present disclosure also relates to a method of cleaning a surface, preferably a textile, where the method includes mixing the cleaning composition according to the present disclosure with water to form an aqueous liquor and contacting a surface, preferably a textile, with the aqueous liquor in a laundering step. 
     The present disclosure also relates to the use of malodor reduction materials in a cleaning composition to enhance the malodor-reducing benefits of a nuclease enzyme. 
    
    
     DETAILED DESCRIPTION OF THE INVENTION 
     The present disclosure relates to cleaning compositions that include a nuclease enzyme and malodor reduction materials. Without wishing to be bound by theory, it is believed that nuclease enzymes are effective at unlocking soil matrices on a target surface (such as a fabric). However, when they do so, malodorous materials can be released into the immediate environment, such as a wash liquor. These malodorous materials can find their way into the headspace during the washing process, particularly in handwash and/or semi-automatic process, leading to an unpleasant washing experience for the consumer. Malodor reduction materials in combination with nucleases can improve the washing experience and overall performance of the cleaning compositions by neutralizing the impact of such malodorous materials. 
     The components of the compositions and processes of the present disclosure are described in more detail below. 
     As used herein, the articles “a” and “an” when used in a claim, are understood to mean one or more of what is claimed or described. As used herein, the terms “include,” “includes,” and “including” are meant to be non-limiting. The compositions of the present disclosure can comprise, consist essentially of, or consist of, the components of the present disclosure. 
     The terms “substantially free of” or “substantially free from” may be used herein. This means that the indicated material is at the very minimum not deliberately added to the composition to form part of it, or, preferably, is not present at analytically detectable levels. It is meant to include compositions whereby the indicated material is present only as an impurity in one of the other materials deliberately included. The indicated material may be present, if at all, at a level of less than 1%, or less than 0.1%, or less than 0.01%, or even 0%, by weight of the composition. 
     Unless otherwise noted, all component or composition levels are in reference to the active portion of that component or composition, and are exclusive of impurities, for example, residual solvents or by-products, which may be present in commercially available sources of such components or compositions. 
     All temperatures herein are in degrees Celsius (° C.) unless otherwise indicated. Unless otherwise specified, all measurements herein are conducted at 20° C. and under the atmospheric pressure. 
     In all embodiments of the present disclosure, all percentages are by weight of the total composition, unless specifically stated otherwise. All ratios are weight ratios, unless specifically stated otherwise. 
     It should be understood that every maximum numerical limitation given throughout this specification includes every lower numerical limitation, as if such lower numerical limitations were expressly written herein. Every minimum numerical limitation given throughout this specification will include every higher numerical limitation, as if such higher numerical limitations were expressly written herein. Every numerical range given throughout this specification will include every narrower numerical range that falls within such broader numerical range, as if such narrower numerical ranges were all expressly written herein. 
     As used herein “MORV” is the calculated malodor reduction value for a subject material. A material&#39;s MORV indicates such material&#39;s ability to decrease or even eliminate the perception of one or more malodors. For purposes of the present application, a material&#39;s MORV is calculated in accordance with method found in the test methods section of the present application. 
     As used herein, the term “perfume” does not include malodor reduction materials. Thus, the perfume portion of a composition does not include, when determining the perfume&#39;s composition, any malodor reduction materials found in the composition as such malodor reduction materials are described herein. In short, if a material has a malodor reduction value “MORV” that is within the range of the MORV recited in the subject claim, such material is a malodor reduction material for purposes of such claim. 
     As used herein “cleaning and/or treatment compositions” means products comprising fluid laundry detergents, fabric enhancers, laundry and/or rinse additives, fluid dishwashing detergents, fluid hard surface cleaning and/or treatment compositions, fluid toilet bowl cleaners that may or may not be contained in a unit dose delivery product all for consumer, agricultural, industrial or institutional use. 
     As used herein, “malodor” refers to compounds generally offensive or unpleasant to most people, such as the complex odors associated with bowel movements. 
     As used herein, “odor blocking” refers to the ability of a compound to dull the human sense of smell. 
     As used herein, the term “alkoxy” is intended to include C1-C8 alkoxy and C1-C8 alkoxy derivatives of polyols having repeating units such as butylene oxide, glycidol oxide, ethylene oxide or propylene oxide. 
     As used herein, unless otherwise specified, the terms “alkyl” and “alkyl capped” are intended to include C1-C18 alkyl groups, or even C1-C6 alkyl groups. 
     As used herein, unless otherwise specified, the term “aryl” is intended to include C3-12 aryl groups. 
     As used herein, unless otherwise specified, the term “arylalkyl” and “alkaryl” are equivalent and are each intended to include groups comprising an alkyl moiety bound to an aromatic moiety, typically having C1-C18 alkyl groups and, in one aspect, C1-C6 alkyl groups. 
     The terms “ethylene oxide,” “propylene oxide” and “butylene oxide” may be shown herein by their typical designation of “EO,” “PO” and “BO,” respectively. 
     As used herein, the term “cleaning and/or treatment composition” includes, unless otherwise indicated, granular, powder, liquid, gel, paste, unit dose, bar form and/or flake type washing agents and/or fabric treatment compositions, including but not limited to products for laundering fabrics, fabric softening compositions, fabric enhancing compositions, fabric freshening compositions, and other products for the care and maintenance of fabrics, and combinations thereof. Such compositions may be pre-treatment compositions for use prior to a washing step or may be rinse added compositions, as well as cleaning auxiliaries, such as bleach additives and/or “stain-stick” or pre-treat compositions or substrate-laden products such as dryer added sheets. 
     As used herein, “cellulosic substrates” are intended to include any substrate which comprises cellulose, either 100% by weight cellulose or at least 20% by weight, or at least 30% by weight or at least 40% or at least 50% by weight or even at least 60% by weight cellulose. Cellulose may be found in wood, cotton, linen, jute, and hemp. Cellulosic substrates may be in the form of powders, fibers, pulp and articles formed from powders, fibers and pulp. Cellulosic fibers, include, without limitation, cotton, rayon (regenerated cellulose), acetate (cellulose acetate), triacetate (cellulose triacetate), and mixtures thereof. Typically cellulosic substrates comprise cotton. Articles formed from cellulosic fibers include textile articles such as fabrics. Articles formed from pulp include paper. 
     As used herein, the term “maximum extinction coefficient” is intended to describe the molar extinction coefficient at the wavelength of maximum absorption (also referred to herein as the maximum wavelength), in the range of 400 nanometers to 750 nanometers. 
     As used herein “average molecular weight” is reported as a weight average molecular weight, as determined by its molecular weight distribution; as a consequence of their manufacturing process, polymers disclosed herein may contain a distribution of repeating units in their polymeric moiety. 
     As used herein the term “variant” refers to a polypeptide that contains an amino acid sequence that differs from a wild type or reference sequence. A variant polypeptide can differ from the wild type or reference sequence due to a deletion, insertion, or substitution of a nucleotide(s) relative to said reference or wild type nucleotide sequence. The reference or wild type sequence can be a full-length native polypeptide sequence or any other fragment of a full-length polypeptide sequence. A polypeptide variant generally has at least about 70% amino acid sequence identity with the reference sequence, but may include 75% amino acid sequence identity within the reference sequence, 80% amino acid sequence identity within the reference sequence, 85% amino acid sequence identity with the reference sequence, 86% amino acid sequence identity with the reference sequence, 87% amino acid sequence identity with the reference sequence, 88% amino acid sequence identity with the reference sequence, 89% amino acid sequence identity with the reference sequence, 90% amino acid sequence identity with the reference sequence, 91% amino acid sequence identity with the reference sequence, 92% amino acid sequence identity with the reference sequence, 93% amino acid sequence identity with the reference sequence, 94% amino acid sequence identity with the reference sequence, 95% amino acid sequence identity with the reference sequence, 96% amino acid sequence identity with the reference sequence, 97% amino acid sequence identity with the reference sequence, 98% amino acid sequence identity with the reference sequence, 98.5% amino acid sequence identity with the reference sequence or 99% amino acid sequence identity with the reference sequence. 
     As used herein, the term “solid” includes granular, powder, bar and tablet product forms. 
     As used herein, the term “fluid” includes liquid, gel, paste, and gas product forms. 
     Cleaning Composition 
     The present disclosure relates to cleaning compositions. The cleaning composition may be selected from the group of light duty liquid detergents compositions, heavy duty liquid detergent compositions, hard surface cleaning compositions, detergent gels commonly used for laundry, bleaching compositions, laundry additives, fabric enhancer compositions, shampoos, body washes, other personal care compositions, and mixtures thereof. The cleaning composition may be a hard surface cleaning composition (such as a dishwashing composition) or a laundry composition (such as a heavy duty liquid detergent composition). 
     The cleaning compositions may be in any suitable form. The composition can be selected from a liquid, solid, or combination thereof. As used herein, “liquid” includes free-flowing liquids, as well as pastes, gels, foams and mousses. Non-limiting examples of liquids include light duty and heavy duty liquid detergent compositions, fabric enhancers, detergent gels commonly used for laundry, bleach and laundry additives. Gases, e.g., suspended bubbles, or solids, e.g. particles, may be included within the liquids. A “solid” as used herein includes, but is not limited to, powders, agglomerates, and mixtures thereof. Non-limiting examples of solids include: granules, micro-capsules, beads, noodles, and pearlised balls. Solid compositions may provide a technical benefit including, but not limited to, through-the-wash benefits, pre-treatment benefits, and/or aesthetic effects. 
     The cleaning composition may be in the form of a unitized dose article, such as a tablet or in the form of a pouch. Such pouches typically include a water-soluble film, such as a polyvinyl alcohol water-soluble film, that at least partially encapsulates a composition. Suitable films are available from MonoSol, LLC (Indiana, USA). The composition can be encapsulated in a single or multi-compartment pouch. A multi-compartment pouch may have at least two, at least three, or at least four compartments. A multi-compartmented pouch may include compartments that are side-by-side and/or superposed. The composition contained in the pouch may be liquid, solid (such as powders), or combinations thereof. 
     Nuclease Enzyme 
     The nuclease enzyme is an enzyme capable of cleaving the phosphodiester bonds between the nucleotide sub-units of nucleic acids. The nuclease enzyme herein is preferably a deoxyribonuclease or ribonuclease enzyme or a functional fragment thereof. By functional fragment or part is meant the portion of the nuclease enzyme that catalyzes the cleavage of phosphodiester linkages in the DNA backbone and so is a region of said nuclease protein that retains catalytic activity. Thus it includes truncated, but functional versions, of the enzyme and/or variants and/or derivatives and/or homologues whose functionality is maintained. 
     Preferably the nuclease enzyme is a deoxyribonuclease, preferably selected from any of the classes E.C. 3.1.21.x, where x=1, 2, 3, 4, 5, 6, 7, 8 or 9, E.C. 3.1.22.y where y=1, 2, 4 or 5, E.C. 3.1.30.z where z=1 or 2, E.C. 3.1.31.1 and mixtures thereof. 
     Nucleases in class E.C. 3.1.21.x cleave at the 3′ hydroxyl to liberate 5′ phosphomonoesters as follows: 
     
       
         
         
             
             
         
       
     
     Nuclease enzymes from class E.C. 3.1.21.x and especially where x=1 are particularly preferred. 
     Nucleases in class E.C. 3.1.22.y cleave at the 5′ hydroxyl to liberate 3′ phosphomonoesters. Enzymes in class E.C. 3.1.30.z may be preferred as they act on both DNA and RNA and liberate 5′-phosphomonoesters. Suitable examples from class E.C. 3.1.31.2 are described in US2012/0135498A, such as SEQ ID NO:3 therein. Such enzymes are commercially available as DENARASE® enzyme from c-LECTA. 
     Nuclease enzymes from class E.C. 3.1.31.1 produce 3′phosphomonoesters. 
     Preferably, the nuclease enzyme comprises a microbial enzyme. The nuclease enzyme may be fungal or bacterial in origin. Bacterial nucleases may be most preferred. Fungal nucleases may be most preferred. 
     The microbial nuclease is obtainable from  Bacillus , such as a  Bacillus licheniformis  or  Bacillus subtilis  bacterial nucleases. A preferred nuclease is obtainable from  Bacillus licheniformis , preferably from strain EI-34-6. A preferred deoxyribonuclease is a variant of  Bacillus licheniformis , from strain EI-34-6 nucB deoxyribonuclease defined in SEQ ID NO:1 herein, or variant thereof, for example having at least 70% or 75% or 80% or 85% or 90% or 95%, 96%, 97%, 98%, 99% or 100% identical thereto. 
     Other suitable nucleases are defined in SEQ ID NO:2 herein, or variant thereof, for example having at least 70% or 75% or 80% or 85% or 90% or 95%, 96%, 97%, 98%, 99% or 100% identical thereto. Other suitable nucleases are defined in SEQ ID NO:3 herein, or variant thereof, for example having at least 70% or 75% or 80% or 85% or 90% or 95%, 96%, 97%, 98%, 99% or 100% identical thereto. 
     A fungal nuclease is obtainable from  Aspergillus , for example  Aspergillus oryzae . A preferred nuclease is obtainable from  Aspergillus oryzae  defined in SEQ ID NO: 5 herein, or variant thereof, for example having at least 60% or 70% or 75% or 80% or 85% or 90% or 95%, 96%, 97%, 98%, 99% or 100% identical thereto. 
     Another suitable fungal nuclease is obtainable from  Trichoderma , for example  Trichoderma harzianum . A preferred nuclease is obtainable from  Trichoderma harzianum  defined in SEQ ID NO: 6 herein, or variant thereof, for example having at least 60% or 70% or 75% or 80% or 85% or 90% or 95%, 96%, 97%, 98%, 99% or 100% identical thereto. 
     Other fungal nucleases include those encoded by the DNA sequences of  Aspergillus oryzae  RIB40,  Aspergillus oryzae  3.042,  Aspergillus flavus  NRRL3357,  Aspergillus parasiticus  SU-1,  Aspergillus  nomius NRRL13137,  Trichoderma reesei  QM6a,  Trichoderma virens  Gv29-8 , Oidiodendron maius  Zn,  Metarhizium guizhouense  ARSEF 977 , Metarhizium majus  ARSEF 297 , Metarhizium robertsii  ARSEF 23 , Metarhizium acridum  CQMa 102 , Metarhizium brunneum  ARSEF 3297 , Metarhizium anisopliae, Colletotrichum fioriniae  PJ7,  Colletotrichum sublineola, Trichoderma atroviride  IMI 206040,  Tolypocladium ophioglossoides  CBS 100239,  Beauveria bassiana  ARSEF 2860,  Colletotrichum higginsianum, Hirsutella minnesotensis  3608 , Scedosporium apiospermum, Phaeomoniella chlamydospora, Fusarium verticillioides  7600,  Fusarium oxysporum  f. sp.  cubense  race 4,  Colletotrichum graminicola  M1.001,  Fusarium oxysporum  FOSC 3-a,  Fusarium avenaceum, Fusarium langsethiae, Grosmannia clavigera  kw1407,  Claviceps purpurea  20.1,  Verticillium longisporum, Fusarium oxysporum  f. sp.  cubense  race 1,  Magnaporthe oryzae  70-15,  Beauveria bassiana  D1-5,  Fusarium pseudograminearum  CS3096 , Neonectria ditissima, Magnaporthiopsis poae  ATCC 64411,  Cordyceps militaris  CM01,  Marssonina brunnea  f. sp. ‘multigermtubi’ MB_ml,  Diaporthe ampelina, Metarhizium album  ARSEF 1941,  Colletotrichum gloeosporioides  Nara gc5 , Madurella mycetomatis, Metarhizium brunneum  ARSEF 3297,  Verticillium alfalfae  VaMs.102 , Gaeumannomyces graminis  var.  tritici  R3-111a-1,  Nectria haematococca  mpVI 77-13-4,  Verticillium longisporum, Verticillium dahliae  VdLs.17 , Torrubiella hemipterigena, Verticillium longisporum, Verticillium dahliae  VdLs.17,  Botrytis cinerea  B05.10,  Chaetomium globosum  CBS 148.51 , Metarhizium anisopliae, Stemphylium lycopersici, Sclerotinia borealis  F-4157 , Metarhizium robertsii  ARSEF 23,  Myceliophthora thermophila  ATCC 42464 , Phaeosphaeria nodorum  SN15,  Phialophora attae, Ustilaginoidea virens, Diplodia seriata, Ophiostoma piceae  UAMH 11346 , Pseudogymnoascus pannorum  VKM F-4515 (FW-2607),  Bipolaris oryzae  ATCC 44560 , Metarhizium guizhouense  ARSEF 977,  Chaetomium thermophilum  var.  thermophilum  DSM 1495,  Pestalotiopsis fici  W106-1,  Bipolaris zeicola  26-R-13,  Setosphaeria turcica  Et28A,  Arthroderma otae  CBS 113480 and  Pyrenophora tritici -repentis Pt-1C-BFP. 
     Preferably the nuclease is an isolated nuclease. 
     Preferably the nuclease enzyme is present in a the laundering aqueous solution in an amount of from 0.01 ppm to 1000 ppm of the nuclease enzyme, or from 0.05 or from 0.1 ppm to 750 or 500 ppm. 
     The nucleases may also give rise to biofilm-disrupting effects. 
     In a preferred composition, the composition additionally comprises a 13-N-acetylglucosaminidase enzyme from E.C. 3.2.1.52, preferably an enzyme having at least 70%, or at least 75% or at least 80% or at least 85% or at least 90% or at least 95% or at least 96% or at least 97% or at least 98% or at least 99% or at least or 100% identity to SEQ ID NO:4. 
     Malodor Reduction Materials 
     The cleaning compositions of the present disclosure comprise malodour reduction materials. As described above, such materials are capable of decreasing or even eliminating the perception of one or more malodors. These materials can be characterized by a calculated malodor reduction value (“MORV”), which is calculated according to the test method shown below. 
     As used herein “MORV” is the calculated malodor reduction value for a subject material. A material&#39;s MORV indicates such material&#39;s ability to decrease or even eliminate the perception of one or more malodors. For purposes of the present application, a material&#39;s MORV is calculated in accordance with method found in the test methods section of the present application. 
     The cleaning compositions of the present disclosure may comprise a sum total of from about 0.00025% to about 0.5%, preferably from about 0.0025% to about 0.1%, more preferably from about 0.005% to about 0.075%, most preferably from about 0.01% to about 0.05%, by weight of the composition, of 1 or more malodor reduction materials. The cleaning composition may comprise from about 1 to about 20 malodor reduction materials, more preferably 1 to about 15 malodor reduction materials, most preferably 1 to about 10 malodor reduction materials. 
     One, some, or each of the malodor reduction materials may have a MORV of at least 0.5, preferably from 0.5 to 10, more preferably from 1 to 10, most preferably from 1 to 5. One, some, or each of the malodor reduction materials may have a Universal MORV, defined as all of the MORV values of &gt;0.5 for the malodors tested as described herein. The sum total of malodor reduction materials may have a Blocker Index of less than 3, more preferable less than about 2.5, even more preferably less than about 2, and still more preferably less than about 1, and most preferably about 0. The sum total of malodor reduction materials may have a Blocker Index average of from about 3 to about 0.001. 
     In the cleaning compositions of the present disclosure, the malodor reduction materials may have a Fragrance Fidelity Index of less than 3, preferably less than 2, more preferably less than 1 and most preferably about 0 and/or a Fragrance Fidelity Index average of 3 to about 0.001 Fragrance Fidelity Index. As the Fragrance Fidelity Index decreases, the malodor reduction material(s) provide less and less of a scent impact, while continuing to counteract malodors. 
     The cleaning compositions of the present disclosure may comprise a perfume. The weight ratio of parts of malodor reduction composition to parts of perfume may be from about 1:20,000 to about 3000:1, preferably from about 1:10,000 to about 1,000:1, more preferably from about 5,000:1 to about 500:1, and most preferably from about 1:15 to about 1:1. As the ratio of malodor reduction composition to parts of perfume is tightened, the malodor reduction material(s) provide less and less of a scent impact, while continuing to counteract malodors. 
     The cleaning compositions may comprise one or more malodor reduction materials having a log P greater than 3, preferably greater than 3 but less than 8. The one or more malodor reduction materials may be selected from the group consisting of Table 1 materials 7; 14; 39; 48; 183; 206; 212; 215; 229; 248; 260; 261; 329; 335; 360; 441; 484; 487; 488; 501; 566; 567; 569; 570; 573; 574; 603; 616; 621; 624; 632; 663; 680; 684; 694; 696; 708; 712; 714; 726; 750; 775; 776; 788; 804; 872; 919; 927; 933; 978; 1007; 1022; 1024; 1029; 1035; 1038; 1060; 1089; 1107; 1129; 1131; 1136; 1137; 1140; 1142; 1143; 1144; 1145; 1148, 1149 and mixtures thereof, most preferably said material is selected from the group consisting of Table 1 materials 261; 680; 788; 1129, 1148, 1149 and mixtures thereof. All of the aforementioned materials have a log P that is equal to or greater than 3, thus they deposit through the wash especially well. The more preferred and most preferred of the aforementioned material are particularly preferred as they are effective at counteracting all of the key malodors. 
     The cleaning compositions described herein may comprise one or more malodor reduction materials having a vapor pressure of greater than about 0.01 torr, preferably greater than about 0.01 torr to about 10 torr. The one or more malodor materials may be selected from the group consisting of Table 1 materials 7; 229; 281; 441; 603; 621; 627; 632; 696; 708; 714; 750; 1060; 1137; 1144; 1145 and mixtures thereof. All of the aforementioned materials have a vapor pressure that is greater than 0.01 torr, thus they effectively saturate the head space of a cleaning and/or treatment composition, wash solutions comprising same and a treated situs which leads to malodor blocking of any malodors in the cleaning and/or treatment composition, wash solutions comprising same and a treated situs. The more preferred and most preferred of the aforementioned material are particularly preferred as they are effective at counteracting all of the key malodors. 
     A non-limiting set of suitable malodor reduction materials are provided in Table 1 below. The cleaning compositions described herein may comprise a malodor reduction material selected from any of the materials listed in Table 1, or combinations thereof. For ease of reference herein, each material in Table 1 is assigned a numerical identifier which is found in the column for each table that is designated Number. Additional characteristics are provided in Table 1 according to the Comment Codes key shown below. Additional materials and corresponding characteristics are listed, for example, in US Patent Publication No. 2016/0090555 (assigned to The Procter &amp; Gamble Company). 
     
       
         
           
               
             
               
                 TABLE 1 
               
             
            
               
                   
               
               
                 List of materials with ALL MORVs &gt;0.5 
               
            
           
           
               
               
               
               
            
               
                 Number 
                 Material Name 
                 CAS Number 
                 Comment Code 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 2 
                 2,4-dimethyl-2-(5,5,8,8-tetramethyl- 
                 131812-67-4 
                 DFHJ 
               
               
                   
                 5,6,7,8-tetrahydronaphthalen-2-yl)-1,3- 
               
               
                   
                 dioxolane 
               
               
                 7 
                 3-methoxy-7,7-dimethyl-10- 
                 216970-21-7 
                 BDEFHJK 
               
               
                   
                 methylenebicyclo[4.3.1]decane 
               
               
                 13 
                 Oxybenzone 
                 131-57-7 
                 DEFGJ 
               
               
                 14 
                 Oxyoctaline formate 
                 65405-72-3 
                 DFHJK 
               
               
                 23 
                 3a,5,6,7,8,8b-hexahydro-2,2,6,6,7,8,8- 
                 823178-41-2 
                 DEFHJK 
               
               
                   
                 heptamethyl-4H-indeno(4,5-d)-1,3- 
               
               
                   
                 dioxole 
               
               
                 39 
                 2,2,6,8-tetramethyl-1,2,3,4,4a,5,8,8a- 
                 103614-86-4 
                 DEFHIJK 
               
               
                   
                 octahydronaphthalen-1-ol 
               
               
                 48 
                 Nootkatone 
                 4674-50-4 
                 DHJK 
               
               
                 65 
                 1-ethyl-3- 
                 31996-78-8 
                 ACEFHIJKL 
               
               
                   
                 methoxytricyclo[2.2.1.02,6]heptane 
               
               
                 68 
                 10-isopropyl-2,7-dimethyl-1- 
                 89079-92-5 
                 BDEFHIJK 
               
               
                   
                 oxaspiro[4.5]deca-3,6-diene 
               
               
                 100 
                 Methyl stearate 
                 112-61-8 
                 DEFHJ 
               
               
                 105 
                 Methyl linoleate 
                 112-63-0 
                 DEFHJ 
               
               
                 108 
                 Methyl isoeugenol 
                 93-16-3 
                 ACEFHK 
               
               
                 110 
                 Methyl eugenol 
                 93-15-2 
                 ACEFHK 
               
               
                 141 
                 2,4-dimethyl-4,4a,5,9b- 
                 27606-09-3 
                 CEFHJK 
               
               
                   
                 tetrahydroindeno[1,2-d][1,3]dioxine 
               
               
                 143 
                 4-(4-hydroxy-4-methylpentyl)cyclohex- 
                 31906-04-4 
                 CHJ 
               
               
                   
                 3-ene-1-carbaldehyde 
               
               
                 146 
                 (Z)-3-hexen-1-yl-2-cyclopenten-1-one 
                 53253-09-1 
                 BDHK 
               
               
                 161 
                 (2,5-dimethyl-1,3-dihydroinden-2- 
                 285977-85-7 
                 CEFHJK 
               
               
                   
                 yl)methanol 
               
               
                 183 
                 Khusimol 
                 16223-63-5 
                 CEFHJK 
               
               
                 185 
                 (1-methyl-2-((1,2,2- 
                 198404-98-7 
                 DEFHJK 
               
               
                   
                 trimethylbicyclo[3.1.0]hexan-3- 
               
               
                   
                 yl)methyl)cyclopropyl)methanol 
               
               
                 192 
                 2,6,9,10-tetramethyl-1- 
                 71078-31-4 
                 BDEFHIJK 
               
               
                   
                 oxaspiro(4.5)deca-3,6-diene 
               
               
                 195 
                 Isopropyl palmitate 
                 142-91-6 
                 DEFHJ 
               
               
                 199 
                 Isopimpinellin 
                 482-27-9 
                 CFGJ 
               
               
                 206 
                 Iso3-methylcyclopentadecan-1-one 
                 3100-36-5 
                 DEFGJK 
               
               
                 212 
                 Isoeugenyl benzyl ether 
                 120-11-6 
                 DFHJ 
               
               
                 215 
                 1-((2S,3S)-2,3,8,8-tetramethyl- 
                 54464-57-2 
                 DHJK 
               
               
                   
                 1,2,3,4,5,6,7,8-octahydronaphthalen-2- 
               
               
                   
                 yl)ethan-1-one 
               
               
                 227 
                 Isobornylcyclohexanol 
                 68877-29-2 
                 DEFHJK 
               
               
                 228 
                 Isobornyl propionate 
                 2756-56-1 
                 BDEFHIJK 
               
               
                 229 
                 Isobornyl isobutyrate 
                 85586-67-0 
                 BDEFHIJK 
               
               
                 230 
                 Isobornyl cyclohexanol 
                 66072-32-0 
                 DEFHJK 
               
               
                 233 
                 Isobergamate 
                 68683-20-5 
                 DEFHJK 
               
               
                 248 
                 Hydroxymethyl isolongifolene 
                 59056-64-3 
                 BDEFHJK 
               
               
                 260 
                 2,3-dihydro-3,3-dimethyl-1H-indene-5- 
                 173445-44-8 
                 DHJK 
               
               
                   
                 propanal 
               
               
                 261 
                 3-(3,3-dimethyl-2,3-dihydro-1H-inden-5- 
                 173445-65-3 
                 DHJK 
               
               
                   
                 yl)propanal 
               
               
                 281 
                 3a,4,5,6,7,7a-hexahydro-1H-4,7- 
                 5413-60-5 
                 CEFGJK 
               
               
                   
                 methanoinden-6-yl acetate 
               
               
                 292 
                 Guaiol 
                 489-86-1 
                 DEFHJK 
               
               
                 322 
                 gamma-Muurolene 
                 30021-74-0 
                 DEFHJKL 
               
               
                 325 
                 gamma-Himachalene 
                 53111-25-4 
                 BDEFHJKL 
               
               
                 329 
                 gamma-Eudesmol 
                 1209-71-8 
                 DFHJK 
               
               
                 333 
                 gamma-Cadinene 
                 39029-41-9 
                 DEFHJKL 
               
               
                 335 
                 4,6,6,7,8,8-hexamethyl-1,3,4,6,7,8- 
                 1222-05-5 
                 DEFHJK 
               
               
                   
                 hexahydrocyclopenta[g]isochromene 
               
               
                 343 
                 8,8-dimethyl-3a,4,5,6,7,7a-hexahydro- 
                 76842-49-4 
                 DEFHJK 
               
               
                   
                 1H-4,7-methanoinden-6-yl propionate 
               
               
                 353 
                 (Z)-6-ethylideneoctahydro-2H-5,8- 
                 69486-14-2 
                 CEFGJK 
               
               
                   
                 methanochromen-2-one 
               
               
                 359 
                 (E)-4-((3aR,4R,7R,7aR)-1,3a,4,6,7,7a- 
                 501929-47-1 
                 DEFHJK 
               
               
                   
                 hexahydro-5H-4,7-methanoinden-5- 
               
               
                   
                 ylidene)-3-methylbutan-2-ol 
               
               
                 360 
                 8,8-dimethyl-3a,4,5,6,7,7a-hexahydro- 
                 171102-41-3 
                 DEFHJK 
               
               
                   
                 1H-4,7-methanoinden-6-yl acetate 
               
               
                 361 
                 3-(4-ethylphenyl)-2,2- 
                 134123-93-6 
                 DEFHJK 
               
               
                   
                 dimethylpropanenitrile 
               
               
                 371 
                 1-cyclopentadec-4-en-1-one 
                 14595-54-1 
                 DEFGJK 
               
               
                 372 
                 1-cyclopentadec-4-en-1-one 
                 35720-57-1 
                 DEFGJK 
               
               
                 374 
                 Eugenyl acetate 
                 93-28-7 
                 CFHJK 
               
               
                 413 
                 6-ethyl-2,10,10-trimethyl-1- 
                 79893-63-3 
                 BDEFHIJK 
               
               
                   
                 oxaspiro[4.5]deca-3,6-diene 
               
               
                 418 
                 (E)-4-((3aS,7aS)-octahydro-5H-4,7- 
                 30168-23-1 
                 DFHJK 
               
               
                   
                 methanoinden-5-ylidene)butanal 
               
               
                 441 
                 Octahydro-1H-4,7-methanoinden-5-yl 
                 64001-15-6 
                 DEFHJKL 
               
               
                   
                 acetate 
               
               
                 465 
                 delta-Cadinene 
                 483-76-1 
                 DEFHJKL 
               
               
                 467 
                 delta-Amorphene 
                 189165-79-5 
                 DEFHJKL 
               
               
                 472 
                 Decyl anthranilate 
                 18189-07-6 
                 DEFHJ 
               
               
                 484 
                 3a,4,5,6,7,7a-hexahydro-1H-4,7- 
                 113889-23-9 
                 DEFHJK 
               
               
                   
                 methanoinden-6-yl butyrate 
               
               
                 487 
                 3a,4,5,6,7,7a-hexahydro-1H-4,7- 
                 67634-20-2 
                 DEFHJK 
               
               
                   
                 methanoinden-5-yl isobutyrate 
               
               
                 488 
                 Curzerene 
                 17910-09-7 
                 DHJK 
               
               
                 501 
                 (E)-cycloheptadec-9-en-1-one 
                 542-46-1 
                 DEFGJ 
               
               
                 526 
                 (Z)-3-methyl-2-(pent-2-en-1- 
                 488-10-8 
                 BCHIJKL 
               
               
                   
                 yl)cyclopent-2-en-1-one 
               
               
                 559 
                 (E)-1-(2,6,6-trimethylcyclohex-2-en-1- 
                 79-78-7 
                 DHJK 
               
               
                   
                 yl)hepta-1,6-dien-3-one 
               
               
                 561 
                 (3aR,5aR,9aR,9bR)-3a,6,6,9a- 
                 3738-00-9 
                 DEFHJK 
               
               
                   
                 tetramethyldodecahydronaphtho[2,1- 
               
               
                   
                 b]furan 
               
               
                 565 
                 Cedryl methyl ether 
                 19870-74-7 
                 ADEFHJK 
               
               
                 566 
                 Cedryl formate 
                 39900-38-4 
                 BDEFHJK 
               
               
                 567 
                 Cedryl acetate 
                 77-54-3 
                 DEFHJK 
               
               
                 568 
                 (4Z,8Z)-1,5,9-trimethyl-13- 
                 71735-79-0 
                 DFHJK 
               
               
                   
                 oxabicyclo[10.1.0]trideca-4,8-diene 
               
               
                 569 
                 Cedrol 
                 77-53-2 
                 DEFHJK 
               
               
                 570 
                 5-methyl-1-(2,2,3-trimethylcyclopent-3- 
                 139539-66-5 
                 DEFHJK 
               
               
                   
                 en-1-yl)-6-oxabicyclo[3.2.1]octane 
               
               
                 571 
                 5-methyl-1-(2,2,3-trimethylcyclopent-3- 
                 426218-78-2 
                 DFHJ 
               
               
                   
                 en-1-yl)-6-oxabicyclo[3.2.1]octane 
               
               
                 572 
                 1,1,2,3,3-pentamethyl-1,2,3,5,6,7- 
                 33704-61-9 
                 BDEFHIJK 
               
               
                   
                 hexahydro-4H-inden-4-one 
               
               
                 573 
                 Caryophyllene alcohol acetate 
                 32214-91-8 
                 DEFHJK 
               
               
                 574 
                 Caryolan-1-ol 
                 472-97-9 
                 DEFHJK 
               
               
                 603 
                 Bornyl isobutyrate 
                 24717-86-0 
                 BDEFHIJK 
               
               
                 616 
                 beta-Santalol 
                 77-42-9 
                 DEFHJK 
               
               
                 621 
                 beta-Patchoulline 
                 514-51-2 
                 BDEFGJKL 
               
               
                 624 
                 beta-Himachalene Oxide 
                 57819-73-5 
                 BDFHJK 
               
               
                 625 
                 beta-Himachalene 
                 1461-03-6 
                 DEFHJKL 
               
               
                 626 
                 beta-Guaiene 
                 88-84-6 
                 DEFHJKL 
               
               
                 627 
                 (2,2-dimethoxyethyl)benzene 
                 101-48-4 
                 DHJK 
               
               
                 631 
                 beta-Copaene 
                 18252-44-3 
                 BDEFHJKL 
               
               
                 632 
                 beta-Cedrene 
                 546-28-1 
                 BDEFGJKL 
               
               
                 633 
                 beta-Caryophyllene 
                 87-44-5 
                 DEFHJKL 
               
               
                 638 
                 Bergaptene 
                 484-20-8 
                 CGJ 
               
               
                 644 
                 Benzyl laurate 
                 140-25-0 
                 DEFHJ 
               
               
                 659 
                 2′-isopropyl-1,7,7- 
                 188199-50-0 
                 DEFHJK 
               
               
                   
                 trimethylspiro[bicyclo[2.2.1]heptane- 
               
               
                   
                 2,4′-[1,3]dioxane] 
               
               
                 663 
                 Anisyl phenylacetate 
                 102-17-0 
                 DFHJ 
               
               
                 673 
                 (3aR,5aS,9aS,9bR)-3a,6,6,9a- 
                 6790-58-5 
                 DEFHJK 
               
               
                   
                 tetramethyldodecahydronaphtho[2,1- 
               
               
                   
                 b]furan 
               
               
                 674 
                 (4aR,5R,7aS,9R)-2,2,5,8,8,9a- 
                 211299-54-6 
                 DEFHJK 
               
               
                   
                 hexamethyloctahydro-4H-4a,9- 
               
               
                   
                 methanoazuleno[5,6-d][1,3]dioxole 
               
               
                 676 
                 2,5,5-trimethyl-1,2,3,4,5,6,7,8- 
                 41199-19-3 
                 DEFHJK 
               
               
                   
                 octahydronaphthalen-2-ol 
               
               
                 678 
                 (3S,5aR,7aS,11aS,11bR)-3,8,8,11a- 
                 57345-19-4 
                 DEFHJ 
               
               
                   
                 tetramethyldodecahydro-5H-3,5a- 
               
               
                   
                 epoxynaphtho[2,1-c]oxepine 
               
               
                 679 
                 2,2,6,6,7,8,8-heptamethyldecahydro-2H- 
                 476332-65-7 
                 ADEFHJK 
               
               
                   
                 indeno[4,5-b]furan 
               
               
                 680 
                 2,2,6,6,7,8,8-heptamethyldecahydro-2H- 
                 647828-16-8 
                 ADEFHJK 
               
               
                   
                 indeno[4,5-b]furan 
               
               
                 684 
                 alpha-Vetivone 
                 15764-04-2 
                 DHJK 
               
               
                 694 
                 alpha-Santalol 
                 115-71-9 
                 DEFHJK 
               
               
                 696 
                 alpha-Patchoulene 
                 560-32-7 
                 ADEFHJKL 
               
               
                 698 
                 alpha-Muurolene 
                 10208-80-7 
                 DEFHJKL 
               
               
                 700 
                 alpha-methyl ionone 
                 127-42-4 
                 BDHJK 
               
               
                 708 
                 alpha-Gurjunene 
                 489-40-7 
                 BDEFHJKL 
               
               
                 712 
                 alpha-Eudesmol 
                 473-16-5 
                 DEFHJK 
               
               
                 714 
                 alpha-Cubebene 
                 17699-14-8 
                 ADEFHJKL 
               
               
                 715 
                 alpha-Cedrene epoxide 
                 13567-39-0 
                 ADEFHJK 
               
               
                 716 
                 alpha-Cadinol 
                 481-34-5 
                 DEFHJK 
               
               
                 717 
                 alpha-Cadinene 
                 24406-05-1 
                 DEFHJKL 
               
               
                 718 
                 alpha-Bisabolol 
                 515-69-5 
                 DFHJK 
               
               
                 725 
                 alpha-Amorphene 
                 23515-88-0 
                 DEFHJKL 
               
               
                 726 
                 alpha-Agarofuran 
                 5956-12-7 
                 BDEFHJK 
               
               
                 750 
                 Allo-aromadendrene 
                 25246-27-9 
                 BDEFHJKL 
               
               
                 758 
                 Acetoxymethyl-isolongifolene (isomers) 
                 59056-62-1 
                 BDEFHJK 
               
               
                 764 
                 Acetarolle 
                 744266-61-3 
                 DFHJK 
               
               
                 769 
                 (Z)-2-(4-methylbenzylidene)heptanal 
                 84697-09-6 
                 DHJ 
               
               
                 775 
                 7-eip-alpha-Eudesmol 
                 123123-38-6 
                 DEFHJK 
               
               
                 776 
                 7-Acetyl-1,1,3,4,4,6-hexamethyltetralin 
                 1506-02-1 
                 DEFHJ 
               
               
                 788 
                 5-Cyclohexadecenone 
                 37609-25-9 
                 DEFGJK 
               
               
                 803 
                 4-(p-Methoxyphenyl)-2-butanone 
                 104-20-1 
                 BCEFHJK 
               
               
                 804 
                 3-Thujopsanone 
                 25966-79-4 
                 BDEFHJK 
               
               
                 865 
                 2,6-Nonadien-1-ol 
                 7786-44-9 
                 ACEFHK 
               
               
                 872 
                 10-epi-gamma-Eudesmol 
                 15051-81-7 
                 DFHJK 
               
               
                 879 
                 1,1,2,3,3-Pentamethylindan 
                 1203-17-4 
                 ADHIJKL 
               
               
                 893 
                 (2S,5S,6S)-2,6,10,10-tetramethyl-1- 
                 65620-50-0 
                 DFHIJK 
               
               
                   
                 oxaspiro[4_5]decan-6-ol 
               
               
                 912 
                 2-(8-isopropyl-6- 
                 68901-32-6 
                 DEFHJK 
               
               
                   
                 methylbicyclo[2.2.2]oct-5-en-2-yl)-1,3- 
               
               
                   
                 dioxolane 
               
               
                 919 
                 3a,4,5,6,7,7a-hexahydro-1H-4,7- 
                 17511-60-3 
                 CEFHJK 
               
               
                   
                 methanoinden-6-yl propionate 
               
               
                 920 
                 Bulnesol 
                 22451-73-6 
                 DEFHJK 
               
               
                 923 
                 Benzoin 
                 119-53-9 
                 CEFHJ 
               
               
                 927 
                 5-Acetyl-1,1,2,3,3,6-hexamethylindan 
                 15323-35-0 
                 DEFHJK 
               
               
                 933 
                 Patchouli alcohol 
                 5986-55-0 
                 DEFHIJK 
               
               
                 948 
                 Perillyl alcohol 
                 536-59-4 
                 CHIJK 
               
               
                 959 
                 Phenethyl phenylacetate 
                 102-20-5 
                 DHJ 
               
               
                 962 
                 Phenoxanol 
                 55066-48-3 
                 DEFHJK 
               
               
                 978 
                 3a,4,5,6,7,7a-hexahydro-1H-4,7- 
                 68039-44-1 
                 DEFHJK 
               
               
                   
                 methanoinden-6-yl pivalate 
               
               
                 998 
                 p-Tolyl phenylacetate 
                 101-94-0 
                 DFHJ 
               
               
                 1007 
                 (2R,4a′R,8a′R)-3,7′-dimethyl- 
                 41816-03-9 
                 DEFHJK 
               
               
                   
                 3′,4′,4a′,5′,8′,8a′-hexahydro-1′H- 
               
               
                   
                 spiro[oxirane-2,2′- 
               
               
                   
                 [1,4]methanonaphthalene] 
               
               
                 1008 
                 (Z)-6-ethylideneoctahydro-2H-5,8- 
                 93939-86-7 
                 BCEFHJKL 
               
               
                   
                 methanochromene 
               
               
                 1022 
                 2,2,7,9-tetramethylspiro(5.5)undec-8-en- 
                 502847-01-0 
                 DHIJK 
               
               
                   
                 1-one 
               
               
                 1023 
                 3-methyl-5-(2,2,3-trimethylcyclopent-3- 
                 65113-99-7 
                 DEFHJK 
               
               
                   
                 en-1-yl)pentan-2-ol 
               
               
                 1024 
                 (Z)-2-ethyl-4-(2,2,3-trimethylcyclopent- 
                 28219-61-6 
                 DEFHJK 
               
               
                   
                 3-en-1-yl)but-2-en-1-ol 
               
               
                 1026 
                 5-methoxyoctahydro-1H-4,7- 
                 86803-90-9 
                 CHJK 
               
               
                   
                 methanoindene-2-carbaldehyde 
               
               
                 1027 
                 5-methoxyoctahydro-1H-4,7- 
                 193425-86-4 
                 CHJK 
               
               
                   
                 methanoindene-2-carbaldehyde 
               
               
                 1028 
                 Sclareol 
                 515-03-7 
                 DEFHJ 
               
               
                 1029 
                 Sclareol oxide 
                 5153-92-4 
                 DEFHJK 
               
               
                 1031 
                 Selina-3,7(11)-diene 
                 6813-21-4 
                 DEFHJKL 
               
               
                 1035 
                 Spathulenol 
                 6750-60-3 
                 DEFHJK 
               
               
                 1038 
                 1-(spiro[4.5]dec-7-en-7-yl)pent-4-en-1- 
                 224031-70-3 
                 DGJK 
               
               
                   
                 one 
               
               
                 1046 
                 tau-Cadinol 
                 5937-11-1 
                 DEFHJK 
               
               
                 1047 
                 tau-Muurolol 
                 19912-62-0 
                 DEFHJK 
               
               
                 1060 
                 Thujopsene 
                 470-40-6 
                 BDEFGJKL 
               
               
                 1063 
                 1-(2,2,6-trimethylcyclohexyl)hexan-3-ol 
                 70788-30-6 
                 DEFHJK 
               
               
                 1089 
                 Tricyclone 
                 68433-81-8 
                 DEFHJK 
               
               
                 1093 
                 Methyl 2-((1-hydroxy-3- 
                 144761-91-1 
                 DFHJ 
               
               
                   
                 phenylbutyl)amino)benzoate 
               
               
                 1097 
                 Decahydro-2,6,6,7,8,8-hexamethyl-2h- 
                 338735-71-0 
                 BDEFHJK 
               
               
                   
                 indeno(4,5-b)furan 
               
               
                 1105 
                 Valencene 
                 4630-07-3 
                 BDEFHJK 
               
               
                 1107 
                 Valerianol 
                 20489-45-6 
                 DEFHJK 
               
               
                 1120 
                 1-methoxy-3a,4,5,6,7,7a-hexahydro-1H- 
                 27135-90-6 
                 ACEFHJKL 
               
               
                   
                 4,7-methanoindene 
               
               
                 1129 
                 1-((3R,3aR,7R,8aS)-3,6,8,8-tetramethyl- 
                 32388-55-9 
                 DHJK 
               
               
                   
                 2,3,4,7,8,8a-hexahydro-1H-3a,7- 
               
               
                   
                 methanoazulen-5-yl)ethan-1-one 
               
               
                 1131 
                 Methyl (Z)-2-(((2,4-dimethylcyclohex-3- 
                 68738-99-8 
                 DEFHJ 
               
               
                   
                 en-1-yl)methylene)amino)benzoate 
               
               
                 1135 
                 Vetiverol 
                 89-88-3 
                 CEFHIJK 
               
               
                 1136 
                 Vetivert Acetate 
                 117-98-6 
                 DEFHJK 
               
               
                 1137 
                 Decahydro-3H-spiro[furan-2,5′- 
                 68480-11-5 
                 DEFGJKL 
               
               
                   
                 [4,7]methanoindene] 
               
               
                 1139 
                 (Z)-cyclooct-4-en-1-yl methyl carbonate 
                 87731-18-8 
                 BCHJKL 
               
               
                 1140 
                 (1aR,4S,4aS,7R,7aS,7bS)-1,1,4,7- 
                 552-02-3 
                 DEFHJK 
               
               
                   
                 tetramethyldecahydro-1H- 
               
               
                   
                 cyclopropalelazulen-4-ol 
               
               
                 1142 
                 3,5,5,6,7,8,8-heptamethyl-5,6,7,8- 
                 127459-79-4 
                 DHJ 
               
               
                   
                 tetrahydronaphthalene-2-carbonitrile 
               
               
                 1143 
                 (1S,2S,3S,5R)-2,6,6- 
                 133636-82-5 
                 DEFHJK 
               
               
                   
                 trimethylspiro[bicyclo[3.1.1]heptane- 
               
               
                   
                 3,1′-cyclohexan]-2′-en-4′-one 
               
               
                 1144 
                 1′,1′,5′,5′-tetramethylhexahydro- 
                 154171-76-3 
                 DEFHJK 
               
               
                   
                 2′H,5′H-spiro[[1,3]dioxolane-2,8′- 
               
               
                   
                 [2,4a]methanonaphthalene] 
               
               
                 1145 
                 1′,1′,5′,5′-tetramethylhexahydro- 
                 154171-77-4 
                 DEFHJK 
               
               
                   
                 2′H,5′H-spiro[[1,3]dioxolane-2,8′- 
               
               
                   
                 [2,4a]methanonaphthalene] K 
               
               
                 1146 
                 4-(4-hydroxy-3-methoxyphenyl)butan-2- 
                 122-48-5 
                 CEFGJ 
               
               
                   
                 one 
               
               
                 1147 
                 (1R,8aR)-4-isopropyl-1,6-dimethyl- 
                 41929-05-9 
                 DEFHJKL 
               
               
                   
                 1,2,3,7,8,8a-hexahydronaphthalene 
               
               
                 1148 
                 4,5-epoxy-4,11,11-trimethyl-8- 
                 1139-30-6 
                 DEFHJK 
               
               
                   
                 methylenebicyclo(7.2.0)undecane 
               
               
                 1149 
                 1,3,4,6,7,8alpha-hexahydro-1,1,5,5- 
                 23787-90-8 
                 DEFHIJK 
               
               
                   
                 tetramethyl-2H-2,4alpha- 
               
               
                   
                 methanophtalen-8(5H)-one 
               
               
                 1151 
                 1-(2,2-dimethyl-6-methylen cyclohexyl)- 
                 64070-16-2 
                 CEFHJK 
               
               
                   
                 1-penten-3-one 
               
               
                   
               
               
                 Comment Codes 
               
               
                 A = Vapor Pressure &gt; 0.1 torr 
               
               
                 B = Vapor Pressure is between 0.01 torr and 0.1 torr 
               
               
                 C = log P &lt; 3 
               
               
                 D = log P &gt; 3 
               
               
                 E = Probability of Ingredient Color Instability = 0% 
               
               
                 F = Probability of Ingredient Color Instability &lt; 71% 
               
               
                 G = Odor Detection Threshold less than p.ol = 8 
               
               
                 H = Odor Detection Threshold greater than p.ol = 8 
               
               
                 I = Melamine formaldehyde PMC Headspace Response Ratio greater than or equal to 10 
               
               
                 J = Melamine formaldehyde PMC leakage less than or equal to 5% 
               
               
                 K = Log of liquid dish neat product liquid-air partition coefficient greater than or equal to −7 
               
               
                 L = Log of liquid dish neat product liquid-air partition coefficient greater than or equal to −5 
               
            
           
         
       
     
     The materials in Table 1 can be supplied by one or more of the following: Firmenich Inc. of Plainsboro N.J. USA; International Flavor and Fragrance Inc. New York, N.Y. USA; Takasago Corp. Teterboro, N.J. USA; Symrise Inc. Teterboro, N.J. USA; Sigma-Aldrich/SAFC Inc. Carlsbad, Calif. USA; and Bedoukian Research Inc., Danbury, Conn. USA. 
     Table 2 shows the actual MORV values for each material listed in Table 1 above. 
     
       
         
           
               
             
               
                 TABLE 2 
               
             
            
               
                   
               
               
                 Actual MORV values 
               
            
           
           
               
               
               
               
               
            
               
                   
                 MORV 
                   
                   
                 MORV 
               
               
                 Material 
                 value for 
                 MORV Value 
                 MORV Value 
                 value for 
               
               
                 No. 
                 Equation a.) 
                 for Equation b.) 
                 for Equation c.) 
                 Equation d.) 
               
               
                   
               
            
           
           
               
               
               
               
               
            
               
                 2 
                 1.520311929 
                 3.493450446 
                 2.70657265 
                 5.11342862 
               
               
                 7 
                 1.437444636 
                 2.131822996 
                 3.81633465 
                 1.318339345 
               
               
                 13 
                 1.549643217 
                 1.809183231 
                 0.70864531 
                 2.22799611 
               
               
                 14 
                 2.82111224 
                 2.339505033 
                 1.240818 
                 2.502429355 
               
               
                 23 
                 3.702361074 
                 1.399942641 
                 5.23954766 
                 7.089933671 
               
               
                 39 
                 1.083800659 
                 2.069727985 
                 2.48170879 
                 3.205630609 
               
               
                 48 
                 2.370955056 
                 2.783472865 
                 2.68240273 
                 1.221864405 
               
               
                 65 
                 0.972835178 
                 2.797151284 
                 1.53453579 
                 0.857051645 
               
               
                 68 
                 0.527636614 
                 0.590831983 
                 1.02843762 
                 2.208655795 
               
               
                 100 
                 1.654535066 
                 0.995056228 
                 2.35139085 
                 0.543654824 
               
               
                 105 
                 1.654535066 
                 3.654489674 
                 3.13033965 
                 0.544225478 
               
               
                 108 
                 0.532375207 
                 0.826537134 
                 1.21040312 
                 0.690230716 
               
               
                 110 
                 0.54830833 
                 2.916795026 
                 1.40126098 
                 0.690230716 
               
               
                 141 
                 2.067620311 
                 1.424830396 
                 2.33536931 
                 7.644025075 
               
               
                 143 
                 1.736969725 
                 0.991537809 
                 2.5691601 
                 1.227191656 
               
               
                 146 
                 1.912710035 
                 0.926306508 
                 1.81253333 
                 0.494121361 
               
               
                 161 
                 0.475184006 
                 1.99305646 
                 1.90910177 
                 3.288337059 
               
               
                 183 
                 3.195758563 
                 3.886545621 
                 4.29482769 
                 3.829845293 
               
               
                 185 
                 5.61162203 
                 1.40458529 
                 2.86231343 
                 1.035135749 
               
               
                 192 
                 0.65612864 
                 1.231196814 
                 0.75462061 
                 1.514581532 
               
               
                 195 
                 1.18880856 
                 0.704463775 
                 1.99312777 
                 1.419709023 
               
               
                 199 
                 1.493919434 
                 1.45125612 
                 1.95141371 
                 4.403441058 
               
               
                 206 
                 2.147983695 
                 1.291351958 
                 1.64553247 
                 1.626455601 
               
               
                 212 
                 1.367811201 
                 1.689658923 
                 1.8017376 
                 2.525531645 
               
               
                 215 
                 2.264275088 
                 1.360001278 
                 3.25759951 
                 2.147928282 
               
               
                 227 
                 5.317676982 
                 2.824566654 
                 1.73360625 
                 3.103310061 
               
               
                 228 
                 3.323728685 
                 1.554268023 
                 1.8883835 
                 0.957527434 
               
               
                 229 
                 3.218950175 
                 1.464118271 
                 2.47512497 
                 1.214429025 
               
               
                 230 
                 5.242356467 
                 3.482206715 
                 3.50441556 
                 1.614847073 
               
               
                 233 
                 1.312921486 
                 0.816597603 
                 2.17066283 
                 0.472801294 
               
               
                 248 
                 5.81821686 
                 6.320330665 
                 6.14379552 
                 5.214046447 
               
               
                 260 
                 2.4020693 
                 2.669351733 
                 2.36395771 
                 1.910609499 
               
               
                 261 
                 1.978618006 
                 2.732613301 
                 2.19594212 
                 1.683156477 
               
               
                 281 
                 2.201373139 
                 2.228820089 
                 2.03455575 
                 1.720697243 
               
               
                 292 
                 1.2252731 
                 0.720498276 
                 4.33362953 
                 2.202084022 
               
               
                 322 
                 0.956379568 
                 2.838565742 
                 2.7997689 
                 0.805938034 
               
               
                 325 
                 0.791400443 
                 2.454239197 
                 1.54315324 
                 1.416449646 
               
               
                 329 
                 1.800767509 
                 1.372656013 
                 2.09551175 
                 2.849728342 
               
               
                 333 
                 0.956379568 
                 2.838565742 
                 2.7997689 
                 0.805938034 
               
               
                 335 
                 1.931053264 
                 2.306571877 
                 4.45651797 
                 4.474221307 
               
               
                 343 
                 3.375840967 
                 3.294907583 
                 5.0378352 
                 4.14804591 
               
               
                 353 
                 2.347680291 
                 1.432589328 
                 3.81650185 
                 2.28664738 
               
               
                 359 
                 3.169264285 
                 2.326146291 
                 5.44251947 
                 3.621423972 
               
               
                 360 
                 2.824830639 
                 3.29829616 
                 3.43870859 
                 3.771256974 
               
               
                 361 
                 0.772183137 
                 0.62924397 
                 1.14549597 
                 0.743423792 
               
               
                 371 
                 1.933819902 
                 0.975863726 
                 1.62799441 
                 1.492919426 
               
               
                 372 
                 1.933819902 
                 0.975863726 
                 1.62799441 
                 1.492919426 
               
               
                 374 
                 0.940949346 
                 2.935858163 
                 0.52084392 
                 0.847114052 
               
               
                 413 
                 0.630456164 
                 1.538096427 
                 2.10994563 
                 2.45668637 
               
               
                 418 
                 3.678359573 
                 3.437930194 
                 4.42449746 
                 0.716864637 
               
               
                 441 
                 2.349282571 
                 1.734747324 
                 1.71148239 
                 1.274963632 
               
               
                 465 
                 0.940569103 
                 1.267891616 
                 1.68420132 
                 1.263608034 
               
               
                 467 
                 0.940569103 
                 1.267891616 
                 1.68420132 
                 1.263608034 
               
               
                 472 
                 0.605628283 
                 0.938001104 
                 0.50028363 
                 0.743911872 
               
               
                 484 
                 3.269313083 
                 2.336715633 
                 3.65534824 
                 2.158890088 
               
               
                 487 
                 2.889323404 
                 2.226094104 
                 4.12877599 
                 2.184426542 
               
               
                 488 
                 1.062548487 
                 4.75312035 
                 2.78435853 
                 2.01925207 
               
               
                 501 
                 1.992766 
                 1.365055 
                 1.774147 
                 1.760818 
               
               
                 526 
                 0.698504484 
                 0.548193178 
                 0.92265651 
                 0.500152973 
               
               
                 559 
                 1.433732801 
                 2.854621121 
                 1.81079379 
                 0.893806123 
               
               
                 561 
                 1.874725149 
                 0.921395625 
                 3.05642524 
                 2.616508159 
               
               
                 565 
                 3.655479783 
                 3.751479035 
                 5.51820797 
                 3.282822615 
               
               
                 566 
                 4.034374094 
                 3.755759834 
                 4.82506006 
                 3.190861648 
               
               
                 567 
                 4.203811008 
                 3.627632534 
                 4.68751919 
                 3.372829008 
               
               
                 568 
                 1.643514525 
                 0.827299302 
                 0.70706274 
                 2.545428997 
               
               
                 569 
                 2.692371513 
                 3.589810155 
                 4.40390088 
                 4.506937878 
               
               
                 570 
                 1.707556133 
                 2.400065573 
                 1.78745169 
                 2.655458557 
               
               
                 571 
                 1.862893827 
                 2.803280605 
                 0.98209954 
                 3.188564781 
               
               
                 572 
                 1.203581368 
                 0.798608763 
                 2.67898788 
                 1.659633314 
               
               
                 573 
                 2.459623568 
                 2.656773866 
                 3.54771795 
                 2.085649266 
               
               
                 574 
                 2.878405284 
                 1.770500246 
                 4.00464111 
                 4.859737959 
               
               
                 603 
                 3.218950175 
                 1.464118271 
                 2.47512497 
                 1.214429025 
               
               
                 616 
                 2.689328335 
                 3.692579375 
                 2.01499213 
                 1.348800283 
               
               
                 621 
                 3.671429366 
                 1.708460032 
                 4.57083156 
                 1.955988764 
               
               
                 624 
                 2.139270802 
                 2.093130621 
                 2.5533383 
                 3.30383102 
               
               
                 625 
                 0.665423108 
                 1.356936283 
                 1.5515704 
                 1.874119646 
               
               
                 626 
                 1.292942787 
                 0.621140137 
                 2.28513785 
                 1.042322574 
               
               
                 627 
                 1.14724223 
                 −0.51104438 
                 1.01088446 
                 1.51232276 
               
               
                 631 
                 2.622138509 
                 5.106659136 
                 4.48303003 
                 2.115425367 
               
               
                 632 
                 2.450328692 
                 4.670297017 
                 4.54579766 
                 2.15781135 
               
               
                 633 
                 1.560465308 
                 2.636096631 
                 2.45546606 
                 0.920962489 
               
               
                 638 
                 1.921725015 
                 0.758255259 
                 0.81570609 
                 3.615611357 
               
               
                 644 
                 0.85173251 
                 0.664325682 
                 1.88299246 
                 0.951603698 
               
               
                 659 
                 3.996948911 
                 1.915319951 
                 3.03990612 
                 5.764113617 
               
               
                 663 
                 1.521826905 
                 1.097809988 
                 2.13583044 
                 1.30609234 
               
               
                 673 
                 1.874725149 
                 0.921395625 
                 3.05642524 
                 2.616508159 
               
               
                 674 
                 5.912391366 
                 3.468705262 
                 6.81994671 
                 7.217631788 
               
               
                 676 
                 0.623704257 
                 1.523736626 
                 2.50208859 
                 2.474137331 
               
               
                 678 
                 4.818555677 
                 1.506257638 
                 4.96635528 
                 5.508133385 
               
               
                 679 
                 4.332202737 
                 2.699343437 
                 5.65576391 
                 5.021298111 
               
               
                 680 
                 4.042984412 
                 4.75506829 
                 4.65903898 
                 4.913020939 
               
               
                 684 
                 2.349844428 
                 1.181400632 
                 2.15359469 
                 2.136987013 
               
               
                 694 
                 4.858313721 
                 4.772826468 
                 3.58732214 
                 2.558402204 
               
               
                 696 
                 2.99409154 
                 3.843066736 
                 2.50597637 
                 1.205022789 
               
               
                 698 
                 0.983060431 
                 2.328872529 
                 1.67788951 
                 0.805938034 
               
               
                 700 
                 0.698400489 
                 0.514637899 
                 1.14265307 
                 0.816064314 
               
               
                 708 
                 2.391828225 
                 1.877690145 
                 3.85935427 
                 1.647356195 
               
               
                 712 
                 1.936489942 
                 2.528373237 
                 2.13424487 
                 2.393940425 
               
               
                 714 
                 2.3584433 
                 3.778880151 
                 3.4396901 
                 1.593719007 
               
               
                 715 
                 4.023918591 
                 3.403899942 
                 5.07447567 
                 4.880181625 
               
               
                 716 
                 0.981194248 
                 1.73892162 
                 2.21166953 
                 2.738129365 
               
               
                 717 
                 0.983060431 
                 2.328872529 
                 1.67788951 
                 0.805938034 
               
               
                 718 
                 1.241840746 
                 3.430871861 
                 0.55000978 
                 1.073616332 
               
               
                 725 
                 0.983060431 
                 2.328872529 
                 1.67788951 
                 0.805938034 
               
               
                 726 
                 2.887615733 
                 3.282342953 
                 1.95034945 
                 2.462290186 
               
               
                 750 
                 2.554017714 
                 3.544542579 
                 4.42317523 
                 1.647356195 
               
               
                 758 
                 5.933043009 
                 5.716461604 
                 6.67410554 
                 4.433272782 
               
               
                 764 
                 1.695705 
                 3.388013 
                 2.181775 
                 3.284744 
               
               
                 769 
                 1.889999468 
                 1.112266205 
                 0.82815523 
                 0.525271623 
               
               
                 775 
                 1.936489942 
                 2.528373237 
                 2.13424487 
                 2.393940425 
               
               
                 776 
                 1.495019673 
                 4.35984375 
                 2.59969954 
                 2.95313487 
               
               
                 788 
                 2.147983695 
                 1.250042565 
                 1.72576392 
                 1.626956379 
               
               
                 803 
                 1.706162052 
                 0.623892414 
                 0.59662073 
                 0.7745661 
               
               
                 804 
                 3.478490379 
                 2.348697011 
                 3.96279011 
                 2.456963386 
               
               
                 865 
                 1.670680003 
                 1.916382859 
                 0.6998144 
                 1.124089601 
               
               
                 872 
                 1.800767509 
                 1.372656013 
                 2.09551175 
                 2.849728342 
               
               
                 879 
                 1.187592149 
                 1.464239711 
                 0.67009263 
                 1.103774764 
               
               
                 893 
                 0.869958847 
                 0.843158237 
                 0.61532515 
                 3.158279932 
               
               
                 912 
                 0.530707518 
                 0.774109528 
                 3.0396125 
                 4.394775258 
               
               
                 919 
                 2.891894151 
                 2.295157633 
                 3.54101626 
                 1.984030826 
               
               
                 920 
                 1.292959895 
                 0.808281618 
                 2.92956952 
                 2.204248324 
               
               
                 923 
                 1.340862559 
                 0.503169303 
                 0.53213093 
                 3.164832031 
               
               
                 927 
                 1.879182741 
                 3.409153142 
                 2.48473663 
                 3.409954437 
               
               
                 933 
                 3.702965303 
                 3.03402795 
                 4.33630831 
                 4.238503729 
               
               
                 948 
                 0.592575441 
                 1.383482681 
                 0.93567635 
                 1.058669028 
               
               
                 959 
                 1.609198886 
                 0.500797943 
                 0.795571 
                 0.908389449 
               
               
                 962 
                 1.836429446 
                 0.208275147 
                 −0.14300625 
                 1.067462181 
               
               
                 978 
                 2.201759817 
                 2.123549573 
                 3.7881607 
                 2.358768953 
               
               
                 998 
                 2.197271885 
                 1.578871826 
                 0.90563334 
                 1.056619658 
               
               
                 1007 
                 4.040291133 
                 3.474551355 
                 3.57146797 
                 3.565985043 
               
               
                 1008 
                 0.764519082 
                 0.917635102 
                 2.88258762 
                 2.319622474 
               
               
                 1022 
                 1.364966718 
                 1.690570939 
                 2.05914194 
                 2.364375484 
               
               
                 1023 
                 2.154641091 
                 0.800066339 
                 0.85365652 
                 0.965810338 
               
               
                 1024 
                 2.302280068 
                 1.252164308 
                 1.73414439 
                 1.549538352 
               
               
                 1026 
                 2.97722987 
                 2.096441965 
                 3.87172868 
                 0.550274831 
               
               
                 1027 
                 2.474381478 
                 1.950326182 
                 3.81861867 
                 1.366897355 
               
               
                 1028 
                 1.778414353 
                 3.114931059 
                 4.47690731 
                 6.054314034 
               
               
                 1029 
                 3.672910795 
                 2.760483725 
                 3.26915034 
                 3.042677588 
               
               
                 1031 
                 2.012732245 
                 2.293857161 
                 0.54405555 
                 1.261882121 
               
               
                 1035 
                 2.506372295 
                 3.419954592 
                 4.58206882 
                 4.134341651 
               
               
                 1038 
                 2.753559643 
                 3.81185814 
                 2.71344734 
                 2.243351472 
               
               
                 1046 
                 0.981194248 
                 1.73892162 
                 2.21166953 
                 2.738129365 
               
               
                 1047 
                 0.981194248 
                 1.73892162 
                 2.21166953 
                 2.738129365 
               
               
                 1060 
                 3.311161199 
                 3.074783921 
                 2.10199297 
                 1.822541682 
               
               
                 1063 
                 1.385675542 
                 0.738759296 
                 1.1677069 
                 0.501211562 
               
               
                 1089 
                 2.769817302 
                 1.661618789 
                 3.97585272 
                 1.059236597 
               
               
                 1093 
                 0.72304265 
                 1.667011476 
                 2.53982093 
                 2.7903213 
               
               
                 1097 
                 4.407270402 
                 2.670641491 
                 5.02636153 
                 5.361271976 
               
               
                 1105 
                 2.387326861 
                 3.865456674 
                 2.2251199 
                 0.728667998 
               
               
                 1107 
                 2.352582059 
                 2.595496601 
                 3.20492728 
                 2.844590737 
               
               
                 1120 
                 0.953790113 
                 1.106552668 
                 3.00006904 
                 1.585038764 
               
               
                 1129 
                 3.18966648 
                 3.284362987 
                 4.49398568 
                 3.950809104 
               
               
                 1131 
                 1.650621055 
                 1.545704806 
                 2.37535081 
                 1.259373143 
               
               
                 1135 
                 0.626973385 
                 1.998305877 
                 2.61706075 
                 1.570404253 
               
               
                 1136 
                 2.812199484 
                 1.353198146 
                 2.05618426 
                 1.869204406 
               
               
                 1137 
                 2.208307057 
                 1.387136198 
                 3.21521374 
                 2.069795393 
               
               
                 1139 
                 1.408517438 
                 0.890457374 
                 1.24524408 
                 0.685687797 
               
               
                 1140 
                 2.765860952 
                 2.525539595 
                 4.12464228 
                 3.833744077 
               
               
                 1142 
                 2.54335679 
                 4.298105601 
                 3.36234238 
                 2.684404542 
               
               
                 1143 
                 4.204367611 
                 3.062126931 
                 3.4234313 
                 2.072899554 
               
               
                 1144 
                 2.479165229 
                 3.226545885 
                 4.65897152 
                 4.952127235 
               
               
                 1145 
                 2.479158921 
                 3.226545885 
                 4.65897152 
                 4.952127235 
               
               
                 1146 
                 0.774334025 
                 1.075800774 
                 1.06893156 
                 1.011113116 
               
               
                 1147 
                 0.844648531 
                 1.21935371 
                 2.59138595 
                 0.805938034 
               
               
                 1148 
                 2.906236436 
                 1.550674121 
                 3.56959167 
                 2.832126896 
               
               
                 1149 
                 2.837627443 
                 3.707154326 
                 4.53384262 
                 2.625871865 
               
               
                 1151 
                 0.663392406 
                 1.217197666 
                 2.133352421 
                 0.816460278 
               
               
                   
               
            
           
         
       
     
     Adjuncts 
     The cleaning compositions described herein may include other adjunct components. The cleaning compositions may comprise a surfactant system as described below. The cleaning composition may comprise a fabric shading agent as described below and/or an additional enzyme selected from lipases, amylases, proteases, mannanases, pectate lyases, cellulases, cutinases, and mixtures thereof. The cleaning composition may comprise a cleaning cellulase. 
     The composition may comprise a fabric shading agent. Suitable fabric shading agents include dyes, dye-clay conjugates, and pigments. Suitable dyes include small molecule dyes and polymeric dyes. Suitable small molecule dyes include small molecule dyes selected from the group consisting of dyes falling into the Colour Index (C.I.) classifications of Direct Blue, Direct Red, Direct Violet, Acid Blue, Acid Red, Acid Violet, Basic Blue, Basic Violet and Basic Red, or mixtures thereof. Preferred dyes include alkoxylated azothiophenes, Solvent Violet 13, Acid Violet 50 and Direct Violet 9. 
     The cleaning compositions described herein may include one or more of the following non-limiting list of ingredients: fabric care benefit agent; detersive enzyme; deposition aid; rheology modifier; builder; chelant; bleach; bleaching agent; bleach precursor; bleach booster; bleach catalyst; perfume and/or perfume microcapsules; perfume loaded zeolite; starch encapsulated accord; polyglycerol esters; whitening agent; pearlescent agent; enzyme stabilizing systems; scavenging agents including fixing agents for anionic dyes, complexing agents for anionic surfactants, and mixtures thereof; optical brighteners or fluorescers; polymer including but not limited to soil release polymer and/or soil suspension polymer; dispersants; antifoam agents; non-aqueous solvent; fatty acid; suds suppressors, e.g., silicone suds suppressors; cationic starches; scum dispersants; substantive dyes; colorants; opacifier; antioxidant; hydrotropes such as toluenesulfonates, cumenesulfonates and naphthalenesulfonates; color speckles; colored beads, spheres or extrudates; clay softening agents; anti-bacterial agents. Additionally or alternatively, the compositions may comprise surfactants, quaternary ammonium compounds, and/or solvent systems. Quaternary ammonium compounds may be present in fabric enhancer compositions, such as fabric softeners, and comprise quaternary ammonium cations that are positively charged polyatomic ions of the structure NR 4   + , where R is an alkyl group or an aryl group. 
     Surfactant System 
     The cleaning composition may comprise a surfactant system. The cleaning composition may comprise from about 1% to about 80%, or from 1% to about 60%, preferably from about 5% to about 50% more preferably from about 8% to about 40%, by weight of the cleaning composition, of a surfactant system. 
     Surfactants of the present surfactant system may be derived from natural and/or renewable sources. 
     The surfactant system may comprise an anionic surfactant, more preferably an anionic surfactant selected from the group consisting of alkyl sulfate, alkyl alkoxy sulfate, especially alkyl ethoxy sulfate, alkyl benzene sulfonate, paraffin sulfonate and mixtures thereof. The surfactant system may further comprise a surfactant selected from the group consisting of nonionic surfactant, cationic surfactant, amphoteric surfactant, zwitterionic surfactant, and mixtures thereof. The surfactant system may comprise an amphoteric surfactant; the amphoteric surfactant may comprise an amine oxide surfactant. The surfactant system may comprise a nonionic surfactant; the nonionic surfactant may comprise an ethoxylated nonionic surfactant. 
     Alkyl sulfates are preferred for use herein and also alkyl ethoxy sulfates; more preferably a combination of alkyl sulfates and alkyl ethoxy sulfates with a combined average ethoxylation degree of less than 5, preferably less than 3, more preferably less than 2 and more than 0.5 and an average level of branching of from about 5% to about 40%. 
     The composition of the invention comprises amphoteric and/or zwitterionic surfactant, preferably the amphoteric surfactant comprises an amine oxide, preferably an alkyl dimethyl amine oxide, and the zwitteronic surfactant comprises a betaine surfactant. 
     The most preferred surfactant system for the detergent composition of the present invention comprise from 1% to 40%, preferably 6% to 35%, more preferably 8% to 30% weight of the total composition of an anionic surfactant, preferably an alkyl alkoxy sulfate surfactant, more preferably an alkyl ethoxy sulfate, combined with 0.5% to 15%, preferably from 1% to 12%, more preferably from 2% to 10% by weight of the composition of amphoteric and/or zwitterionic surfactant, more preferably an amphoteric and even more preferably an amine oxide surfactant, especially and alkyl dimethyl amine oxide. Preferably the composition further comprises a nonionic surfactant, especially an alcohol alkoxylate in particular and alcohol ethoxylate nonionic surfactant. 
     Anionic Surfactant 
     Anionic surfactants include, but are not limited to, those surface-active compounds that contain an organic hydrophobic group containing generally 8 to 22 carbon atoms or generally 8 to 18 carbon atoms in their molecular structure and at least one water-solubilizing group preferably selected from sulfonate, sulfate, and carboxylate so as to form a water-soluble compound. Usually, the hydrophobic group will comprise a C8-C 22 alkyl, or acyl group. Such surfactants are employed in the form of water-soluble salts and the salt-forming cation usually is selected from sodium, potassium, ammonium, magnesium and mono-, di- or tri-C2-C3 alkanolammonium, with the sodium cation being the usual one chosen. 
     The anionic surfactant can be a single surfactant but usually it is a mixture of anionic surfactants. Preferably the anionic surfactant comprises a sulfate surfactant, more preferably a sulfate surfactant selected from the group consisting of alkyl sulfate, alkyl alkoxy sulfate and mixtures thereof. Preferred alkyl alkoxy sulfates for use herein are alkyl ethoxy sulfates. 
     Sulfated Anionic Surfactant 
     Preferably the sulfated anionic surfactant is alkoxylated, more preferably, an alkoxylated branched sulfated anionic surfactant having an alkoxylation degree of from about 0.2 to about 4, even more preferably from about 0.3 to about 3, even more preferably from about 0.4 to about 1.5 and especially from about 0.4 to about 1. Preferably, the alkoxy group is ethoxy. When the sulfated anionic surfactant is a mixture of sulfated anionic surfactants, the alkoxylation degree is the weight average alkoxylation degree of all the components of the mixture (weight average alkoxylation degree). In the weight average alkoxylation degree calculation the weight of sulfated anionic surfactant components not having alkoxylated groups should also be included. 
       Weight average alkoxylation degree=( x 1*alkoxylation degree of surfactant 1+ x 2*alkoxylation degree of surfactant 2+ . . . )/( x 1+ x 2+ . . . ) 
     wherein x1, x2, . . . are the weights in grams of each sulfated anionic surfactant of the mixture and alkoxylation degree is the number of alkoxy groups in each sulfated anionic surfactant. 
     Preferably, the branching group is an alkyl. Typically, the alkyl is selected from methyl, ethyl, propyl, butyl, pentyl, cyclic alkyl groups and mixtures thereof. Single or multiple alkyl branches could be present on the main hydrocarbyl chain of the starting alcohol(s) used to produce the sulfated anionic surfactant used in the detergent of the invention. Most preferably the branched sulfated anionic surfactant is selected from alkyl sulfates, alkyl ethoxy sulfates, and mixtures thereof. 
     The branched sulfated anionic surfactant can be a single anionic surfactant or a mixture of anionic surfactants. In the case of a single surfactant the percentage of branching refers to the weight percentage of the hydrocarbyl chains that are branched in the original alcohol from which the surfactant is derived. 
     In the case of a surfactant mixture the percentage of branching is the weight average and it is defined according to the following formula: 
       Weight average of branching (%)=[( x 1*wt % branched alcohol 1 in alcohol 1+ x 2*wt % branched alcohol 2 in alcohol 2+ . . . )/( x 1+ x 2+ . . . )]*100 
     wherein x1, x2, . . . are the weight in grams of each alcohol in the total alcohol mixture of the alcohols which were used as starting material for the anionic surfactant for the detergent of the invention. In the weight average branching degree calculation the weight of anionic surfactant components not having branched groups should also be included. 
     Suitable sulfate surfactants for use herein include water-soluble salts of C8-C18 alkyl or hydroxyalkyl, sulfate and/or ether sulfate. Suitable counterions include alkali metal cation or ammonium or substituted ammonium, but preferably sodium. 
     The sulfate surfactants may be selected from C8-C18 primary, branched chain and random alkyl sulfates (AS); C8-C18 secondary (2,3) alkyl sulfates; C8-C18 alkyl alkoxy sulfates (AExS) wherein preferably x is from 1-30 in which the alkoxy group could be selected from ethoxy, propoxy, butoxy or even higher alkoxy groups and mixtures thereof. 
     Alkyl sulfates and alkyl alkoxy sulfates are commercially available with a variety of chain lengths, ethoxylation and branching degrees. Commercially available sulfates include, those based on Neodol alcohols ex the Shell company, Lial-Isalchem and Safol ex the Sasol company, natural alcohols ex The Procter &amp; Gamble Chemicals company. 
     Preferably, the anionic surfactant comprises at least 50%, more preferably at least 60% and especially at least 70% of a sulfate surfactant by weight of the anionic surfactant. Especially preferred detergents from a cleaning view point are those in which the anionic surfactant comprises more than 50%, more preferably at least 60% and especially at least 70% by weight thereof of sulfate surfactant and the sulfate surfactant is selected from the group consisting of alkyl sulfates, alkyl ethoxy sulfates and mixtures thereof. Even more preferred are those in which the anionic surfactant is an alkyl ethoxy sulfate with a degree of ethoxylation of from about 0.2 to about 3, more preferably from about 0.3 to about 2, even more preferably from about 0.4 to about 1.5, and especially from about 0.4 to about 1. They are also preferred anionic surfactant having a level of branching of from about 5% to about 40%, even more preferably from about 10% to 35% and especially from about 20% to 30%. 
     Sulfonate Surfactant 
     Suitable anionic sulfonate surfactants for use herein include water-soluble salts of C8-C18 alkyl or hydroxyalkyl sulfonates; C11-C18 alkyl benzene sulfonates (LAS), modified alkylbenzene sulfonate (MLAS) as discussed in WO 99/05243, WO 99/05242, WO 99/05244, WO 99/05082, WO 99/05084, WO 99/05241, WO 99/07656, WO 00/23549, and WO 00/23548; methyl ester sulfonate (MES); and alpha-olefin sulfonate (AOS). Those also include the paraffin sulfonates may be monosulfonates and/or disulfonates, obtained by sulfonating paraffins of 10 to 20 carbon atoms. The sulfonate surfactant also include the alkyl glyceryl sulfonate surfactants. 
     Nonionic Surfactant 
     Nonionic surfactant, when present, is comprised in a typical amount of from 0.1% to 40%, preferably 0.2% to 20%, most preferably 0.5% to 10% by weight of the composition. Suitable nonionic surfactants include the condensation products of aliphatic alcohols with from 1 to 25 moles of ethylene oxide. The alkyl chain of the aliphatic alcohol can either be straight or branched, primary or secondary, and generally contains from 8 to 22 carbon atoms. Particularly preferred are the condensation products of alcohols having an alkyl group containing from 10 to 18 carbon atoms, preferably from 10 to 15 carbon atoms with from 2 to 18 moles, preferably 2 to 15, more preferably 5-12 of ethylene oxide per mole of alcohol. Highly preferred nonionic surfactants are the condensation products of guerbet alcohols with from 2 to 18 moles, preferably 2 to 15, more preferably 5-12 of ethylene oxide per mole of alcohol. 
     Other suitable non-ionic surfactants for use herein include fatty alcohol polyglycol ethers, alkylpolyglucosides and fatty acid glucamides. 
     Amphoteric Surfactant 
     The surfactant system may include amphoteric surfactant, such as amine oxide. Preferred amine oxides are alkyl dimethyl amine oxide or alkyl amido propyl dimethyl amine oxide, more preferably alkyl dimethyl amine oxide and especially coco dimethyl amino oxide Amine oxide may have a linear or mid-branched alkyl moiety. Typical linear amine oxides include water-soluble amine oxides containing one R1 C8-18 alkyl moiety and 2 R2 and R3 moieties selected from the group consisting of C1-3 alkyl groups and C1-3 hydroxyalkyl groups. Preferably amine oxide is characterized by the formula R1-N(R2)(R3) 0 wherein R1 is a C8-18 alkyl and R2 and R3 are selected from the group consisting of methyl, ethyl, propyl, isopropyl, 2-hydroxethyl, 2-hydroxypropyl and 3-hydroxypropyl. The linear amine oxide surfactants in particular may include linear C10-C18 alkyl dimethyl amine oxides and linear C8-C12 alkoxy ethyl dihydroxy ethyl amine oxides. Preferred amine oxides include linear C10, linear C10-C12, and linear C12-C14 alkyl dimethyl amine oxides. As used herein “mid-branched” means that the amine oxide has one alkyl moiety having n1 carbon atoms with one alkyl branch on the alkyl moiety having n2 carbon atoms. The alkyl branch is located on the a carbon from the nitrogen on the alkyl moiety. This type of branching for the amine oxide is also known in the art as an internal amine oxide. The total sum of n1 and n2 is from 10 to 24 carbon atoms, preferably from 12 to 20, and more preferably from 10 to 16. The number of carbon atoms for the one alkyl moiety (n1) should be approximately the same number of carbon atoms as the one alkyl branch (n2) such that the one alkyl moiety and the one alkyl branch are symmetric. As used herein “symmetric” means that |n1−n2| is less than or equal to 5, preferably 4, most preferably from 0 to 4 carbon atoms in at least 50 wt %, more preferably at least 75 wt % to 100 wt % of the mid-branched amine oxides for use herein. 
     The amine oxide further comprises two moieties, independently selected from a C1-3 alkyl, a C1-3 hydroxyalkyl group, or a polyethylene oxide group containing an average of from about 1 to about 3 ethylene oxide groups. Preferably the two moieties are selected from a C1-3 alkyl, more preferably both are selected as a C1 alkyl. 
     Zwitterionic Surfactant 
     Other suitable surfactants include betaines, such as alkyl betaines, alkylamidobetaine, amidazoliniumbetaine, sulfobetaine (INCI Sultaines) as well as the Phosphobetaine and preferably meets formula (I): 
       R 1 —[CO—X(CH 2 ) n ] x —N + (R 2 )(R 3 )—(CH 2 ) m —[CH(OH)—CH 2 ] y —Y—  (I)
         wherein   R 1  is a saturated or unsaturated C6-22 alkyl residue, preferably C8-18 alkyl residue, in particular a saturated C10-16 alkyl residue, for example a saturated C12-14 alkyl residue;   X is NH, NR 4  with C1-4 Alkyl residue R 4 , O or S,   n a number from 1 to 10, preferably 2 to 5, in particular 3,   x 0 or 1, preferably 1,   R 2 , R 3  are independently a C1-4 alkyl residue, potentially hydroxy substituted such as a hydroxyethyl, preferably a methyl.   m a number from 1 to 4, in particular 1, 2 or 3,   y 0 or 1 and   Y is COO, SO3, OPO(OR 5 )O or P(O)(OR 5 )O, whereby R 5  is a hydrogen atom H or a C1-4 alkyl residue.       

     Preferred betaines are the alkyl betaines of the formula (Ia), the alkyl amido propyl betaine of the formula (Ib), the Sulfo betaines of the formula (Ic) and the Amido sulfobetaine of the formula (Id); 
       R 1 —N + (CH 3 ) 2 —CH 2 COO −   (Ia)
 
       R 1 —CO—NH(CH 2 ) 3 —N + (CH 3 ) 2 —CH 2 COO −   (Ib)
 
       R 1 —N + (CH 3 ) 2 —CH 2 CH(OH)CH 2 SO 3 —  (Ic)
 
       R 1 —CO—NH—(CH 2 ) 3 —N + (CH 3 ) 2 —CH 2 CH(OH)CH 2 SO 3 —  (Id)
 
     in which R 1  has the same meaning as in formula I. Particularly preferred betaines are the Carbobetaine [wherein Y − ═COO − ], in particular the Carbobetaine of the formula (Ia) and (Ib), more preferred are the Alkylamidobetaine of the formula (Ib). 
     Examples of suitable betaines and sulfobetaine are the following [designated in accordance with INCI]: Almondamidopropyl of betaines, Apricotam idopropyl betaines, Avocadamidopropyl of betaines, Babassuamidopropyl of betaines, Behenam idopropyl betaines, Behenyl of betaines, betaines, Canolam idopropyl betaines, Capryl/Capram idopropyl betaines, Carnitine, Cetyl of betaines, Cocamidoethyl of betaines, Cocam idopropyl betaines, Cocam idopropyl Hydroxysultaine, Coco betaines, Coco Hydroxysultaine, Coco/Oleam idopropyl betaines, Coco Sultaine, Decyl of betaines, Dihydroxyethyl Oleyl Glycinate, Dihydroxyethyl Soy Glycinate, Dihydroxyethyl Stearyl Glycinate, Dihydroxyethyl Tallow Glycinate, Dimethicone Propyl of PG-betaines, Erucam idopropyl Hydroxysultaine, Hydrogenated Tallow of betaines, Isostearam idopropyl betaines, Lauram idopropyl betaines, Lauryl of betaines, Lauryl Hydroxysultaine, Lauryl Sultaine, Milkam idopropyl betaines, Minkamidopropyl of betaines, Myristam idopropyl betaines, Myristyl of betaines, Oleam idopropyl betaines, Oleam idopropyl Hydroxysultaine, Oleyl of betaines, Olivamidopropyl of betaines, Palmam idopropyl betaines, Palm itam idopropyl betaines, Palmitoyl Carnitine, Palm Kernelam idopropyl betaines, Polytetrafluoroethylene Acetoxypropyl of betaines, Ricinoleam idopropyl betaines, Sesam idopropyl betaines, Soyam idopropyl betaines, Stearam idopropyl betaines, Stearyl of betaines, Tallowam idopropyl betaines, Tallowam idopropyl Hydroxysultaine, Tallow of betaines, Tallow Dihydroxyethyl of betaines, Undecylenam idopropyl betaines and Wheat Germam idopropyl betaines. 
     A preferred betaine is, for example, Cocoamidopropylbetaine. 
     Methods of Making the Composition 
     The present disclosure relates to methods of making the compositions described herein. The compositions of the invention may be solid (for example granules or tablets) or liquid form. Preferably the compositions are in liquid form. They may be made by any process chosen by the formulator, including by a batch process, a continuous loop process, or combinations thereof. 
     When in the form of a liquid, the compositions of the invention may be aqueous (typically above 2 wt % or even above 5 or 10 wt % total water, up to 90 or up to 80 wt % or 70 wt % total water) or non-aqueous (typically below 2 wt % total water content). Typically the compositions of the invention will be in the form of an aqueous solution or uniform dispersion or suspension of optical brightener, DTI and optional additional adjunct materials, some of which may normally be in solid form, that have been combined with the normally liquid components of the composition, such as the liquid alcohol ethoxylate nonionic, the aqueous liquid carrier, and any other normally liquid optional ingredients. Such a solution, dispersion or suspension will be acceptably phase stable. When in the form of a liquid, the detergents of the invention preferably have viscosity from 1 to 1500 centipoises (1-1500 mPa*s), more preferably from 100 to 1000 centipoises (100-1000 mPa*s), and most preferably from 200 to 500 centipoises (200-500 mPa*s) at 20s-1 and 21° C. Viscosity can be determined by conventional methods. Viscosity may be measured using an AR 550 rheometer from TA instruments using a plate steel spindle at 40 mm diameter and a gap size of 500 μm. The high shear viscosity at 20s-1 and low shear viscosity at 0.05-1 can be obtained from a logarithmic shear rate sweep from 0.1-1 to 25-1 in 3 minutes time at 21 C. The preferred rheology described therein may be achieved using internal existing structuring with detergent ingredients or by employing an external rheology modifier. More preferably the detergents, such as detergent liquid compositions have a high shear rate viscosity of from about 100 centipoise to 1500 centipoise, more preferably from 100 to 1000 cps. Unit Dose detergents, such as detergent liquid compositions have high shear rate viscosity of from 400 to 1000 cps. Detergents such as laundry softening compositions typically have high shear rate viscosity of from 10 to 1000, more preferably from 10 to 800 cps, most preferably from 10 to 500 cps. Hand dishwashing compositions have high shear rate viscosity of from 300 to 4000 cps, more preferably 300 to 1000 cps. 
     The cleaning and/or treatment compositions in the form of a liquid herein can be prepared by combining the components thereof in any convenient order and by mixing, e.g., agitating, the resulting component combination to form a phase stable liquid detergent composition. In a process for preparing such compositions, a liquid matrix is formed containing at least a major proportion, or even substantially all, of the liquid components, e.g., nonionic surfactant, the non-surface active liquid carriers and other optional liquid components, with the liquid components being thoroughly admixed by imparting shear agitation to this liquid combination. For example, rapid stirring with a mechanical stirrer may usefully be employed. While shear agitation is maintained, substantially all of any anionic surfactants and the solid form ingredients can be added. Agitation of the mixture is continued, and if necessary, can be increased at this point to form a solution or a uniform dispersion of insoluble solid phase particulates within the liquid phase. After some or all of the solid-form materials have been added to this agitated mixture, particles of any enzyme material to be included, e.g., enzyme granulates, are incorporated. As a variation of the composition preparation procedure hereinbefore described, one or more of the solid components may be added to the agitated mixture as a solution or slurry of particles premixed with a minor portion of one or more of the liquid components. After addition of all of the composition components, agitation of the mixture is continued for a period of time sufficient to form compositions having the requisite viscosity and phase stability characteristics. Frequently this will involve agitation for a period of from about 30 to 60 minutes. 
     The adjunct ingredients in the compositions of this invention may be incorporated into the composition as the product of the synthesis generating such components, either with or without an intermediate purification step. Where there is no purification step, commonly the mixture used will comprise the desired component or mixtures thereof (and percentages given herein relate to the weight percent of the component itself unless otherwise specified) and in addition unreacted starting materials and impurities formed from side reactions and/or incomplete reaction. For example, for an ethoxylated or substituted component, the mixture will likely comprise different degrees of ethoxylation/substitution. 
     Method of Use 
     The present disclosure relates to methods of using the cleaning compositions of the present disclosure to clean a surface, such as a textile. In general, the method includes mixing the cleaning composition as described herein with water to form an aqueous liquor and contacting a surface, preferably a textile, with the aqueous liquor in a laundering step. The target surface may include a greasy soil. 
     The compositions of this invention, typically prepared as hereinbefore described, can be used to form aqueous washing/treatment solutions for use in the laundering/treatment of fabrics and/or hard surfaces. Generally, an effective amount of such a composition is added to water, for example in a conventional fabric automatic washing machine, to form such aqueous laundering solutions. The aqueous washing solution so formed is then contacted, typically under agitation, with the fabrics to be laundered/treated therewith. An effective amount of the detergent composition herein added to water to form aqueous laundering solutions can comprise amounts sufficient to form from about 500 to 25,000 ppm, or from 500 to 15,000 ppm of composition in aqueous washing solution, or from about 1,000 to 3,000 ppm of the detergent compositions herein will be provided in aqueous washing solution. 
     Typically, the wash liquor is formed by contacting the detergent with wash water in such an amount so that the concentration of the detergent in the wash liquor is from above 0 g/l to 5 g/l, or from 1 g/l, and to 4.5 g/l, or to 4.0 g/l, or to 3.5 g/l, or to 3.0 g/l, or to 2.5 g/l, or even to 2.0 g/l, or even to 1.5 g/l. The method of laundering fabric or textile may be carried out in a top-loading or front-loading automatic washing machine, or can be used in a hand-wash laundry application. In these applications, the wash liquor formed and concentration of laundry detergent composition in the wash liquor is that of the main wash cycle. Any input of water during any optional rinsing step(s) is not included when determining the volume of the wash liquor. 
     The wash liquor may comprise 40 litres or less of water, or 30 litres or less, or 20 litres or less, or 10 litres or less, or 8 litres or less, or even 6 litres or less of water. The wash liquor may comprise from above 0 to 15 litres, or from 2 litres, and to 12 litres, or even to 8 litres of water. Typically from 0.01 kg to 2 kg of fabric per litre of wash liquor is dosed into said wash liquor. Typically from 0.01 kg, or from 0.05 kg, or from 0.07 kg, or from 0.10 kg, or from 0.15 kg, or from 0.20 kg, or from 0.25 kg fabric per litre of wash liquor is dosed into said wash liquor. Optionally, 50 g or less, or 45 g or less, or 40 g or less, or 35 g or less, or 30 g or less, or 25 g or less, or 20 g or less, or even 15 g or less, or even 10 g or less of the composition is contacted to water to form the wash liquor. Such compositions are typically employed at concentrations of from about 500 ppm to about 15,000 ppm in solution. When the wash solvent is water, the water temperature typically ranges from about 5° C. to about 90° C. and, when the situs comprises a fabric, the water to fabric ratio is typically from about 1:1 to about 30:1. Typically the wash liquor comprising the detergent of the invention has a pH of from 3 to 11.5. 
     In one aspect, such method comprises the steps of optionally washing and/or rinsing said surface or fabric, contacting said surface or fabric with any composition disclosed in this specification then optionally washing and/or rinsing said surface or fabric is disclosed, with an optional drying step. 
     Drying of such surfaces or fabrics may be accomplished by any one of the common means employed either in domestic or industrial settings: machine drying or open-air drying. The fabric may comprise any fabric capable of being laundered in normal consumer or institutional use conditions, and the invention is particularly suitable for synthetic textiles such as polyester and nylon and especially for treatment of mixed fabrics and/or fibres comprising synthetic and cellulosic fabrics and/or fibres. As examples of synthetic fabrics are polyester, nylon, these may be present in mixtures with cellulosic fibres, for example, polycotton fabrics. The solution typically has a pH of from 7 to 11, more usually 8 to 10.5. The compositions are typically employed at concentrations from 500 ppm to 5,000 ppm in solution. The water temperatures typically range from about 5° C. to about 90° C. The water to fabric ratio is typically from about 1:1 to about 30:1. 
     Use of Malodor Reduction Materials 
     The present disclosure further relates to a use of malodor reduction materials in a cleaning composition to enhance the malodor-reducing benefits of a nuclease enzyme. 
     COMBINATIONS 
     Specifically contemplated combinations of the disclosure are herein described in the following numbered paragraphs. These combinations are intended to be illustrative in nature and are not intended to be limiting. 
     A. A cleaning composition comprising a nuclease enzyme and one or more malodor reduction materials. 
     B. A cleaning composition according to paragraph A, wherein the nuclease enzyme is a deoxyribonuclease enzyme, a ribonuclease enzyme, or a mixture thereof. 
     C. A cleaning composition according to any of paragraphs A-B, wherein the nuclease enzyme is selected from any of E.C. classes E.C. 3.1.21.x (where x=1, 2, 3, 4, 5, 6, 7, 8, 9), 3.1.22.y (where y=1, 2, 4, 5), E.C. 3.1.30.z (where z=1, 2) or E.C. 3.1.31.1, or mixtures thereof, preferably from E.C. 3.1.21, preferably E.C. 3.1.21.1. 
     D. A cleaning composition according to any of paragraphs A-C, wherein the nuclease enzyme comprises a deoxyribonuclease enzyme. 
     E. A cleaning composition according to any of paragraphs A-D, where the enzyme comprises an enzyme having both RNase and DNase activity, preferably being from E.C. 3.1.30.2. 
     F. A cleaning composition according to any of paragraphs A-E, wherein the nuclease enzyme is a microbial enzyme, preferably a bacterial enzyme. 
     G. A cleaning composition according to any of paragraphs A-F, wherein the enzyme has an amino acid sequence having at least 85%, or at least 90 or at least 95% or even 100% identity with the amino acid sequence shown in SEQ ID NO:1, SEQ ID NO:2 or SEQ ID NO:3. 
     H. A cleaning composition according to any of paragraphs A-G, wherein the composition further comprises a β-N-acetylglucosaminidase enzyme from E.C. 3.2.1.52, preferably an enzyme having at least 70% identity to SEQ ID NO:4. 
     I. A cleaning composition according to any of paragraphs A-H, wherein the cleaning composition comprises a sum total of from about 0.00025% to about 0.5%, by weight of the cleaning composition, of one or more malodor reduction materials. 
     J. A cleaning composition according to any of paragraphs A-I, wherein said one or more malodor reduction material has a MORV of at least 0.5, preferably from 0.5 to 10, more preferably from 1 to 10, most preferably from 1 to 5, as determined by the test methods described herein. 
     K. A cleaning composition according to any of paragraphs A-J, wherein the cleaning composition comprises at least one, preferably all, of the one or more malodor reduction materials has a Universal MORV. 
     L. A cleaning composition according to any of paragraphs A-K, wherein the sum total of the one or more malodor reduction materials in the cleaning composition has a Blocker Index of less than 3, more preferable less than about 2.5, even more preferably less than about 2, and still more preferably less than about 1, and most preferably about 0. 
     M. A cleaning composition according to any of paragraphs A-L, wherein the one or more malodor reduction material has a Fragrance Fidelity Index of less than 3, preferably less than 2, more preferably less than 1, and most preferably about 0. 
     N. A cleaning composition according to any of paragraphs A-M, wherein one or more malodor reduction materials has a log P greater than about 3, preferably greater than about 3 but less than about 8. 
     O. A cleaning composition according to any of paragraphs A-N, wherein one or more malodor reduction materials has a vapor pressure of greater than about 0.01 torr, preferably greater than about 0.01 torr to about 10 torr. 
     P. A cleaning composition according to any of paragraphs A-O, wherein the one or more malodor reduction materials is selected from the group consisting of: 2,4-dimethyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3-dioxolane; 3-methoxy-7,7-dimethyl-10-methylenebicyclo[4.3.1]decane; Oxybenzone; Oxyoctaline formate; 3a,5,6,7,8,8b-hexahydro-2,2,6,6,7,8,8-heptamethyl-4H-indeno(4,5-d)-1,3-dioxole; 3a,5,6,7,8,8b-hexahydro-2,2,6,6,7,8,8-heptamethyl-4H-indeno(4,5-d)-1,3-dioxole; 2,2,6,8-tetramethyl-1,2,3,4,4a,5,8,8a-octahydronaphthalen-1-ol; Nootkatone; 1-ethyl-3-methoxytricyclo[2.2.1.02,6]heptane; 10-isopropyl-2,7-dimethyl-1-oxaspiro[4.5]deca-3,6-diene; Methyl stearate; Methyl linoleate; Methyl isoeugenol; Methyl eugenol; 2,4-dimethyl-4,4a,5,9b-tetrahydroindeno[1,2-d][1,3]dioxine; 4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde; (Z)-3-hexen-1-yl-2-cyclopenten-1-one; (2,5-dimethyl-1,3-dihydroinden-2-yl)methanol; Khusimol; (1-methyl-24-(1,2,2-trimethylbicyclo[3.1.0]hexan-3-yl)methyl)cyclopropyl)methanol; 2,6,9,10-tetramethyl-1-oxaspiro(4.5)deca-3,6-diene; Isopropyl palmitate; Isopimpinellin; Iso3-methylcyclopentadecan-1-one; Isoeugenyl benzyl ether; 1-((2S,3S)-2,3,8,8-tetramethyl-1,2,3,4,5,6,7,8-octahydronaphthalen-2-yl)ethan-1-one; Isobornylcyclohexanol; Isobornyl propionate; Isobornyl isobutyrate; Isobornyl cyclohexanol; Isobergamate; Hydroxymethyl isolongifolene; 2,3-dihydro-3,3-dimethyl-1H-indene-5-propanal; 3-(3,3-dimethyl-2,3-dihydro-1H-inden-5-yl)propanal; 3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoinden-6-yl acetate; Guaiol; gamma-Muurolene; gamma-Himachalene; gamma-Eudesmol; gamma-Cadinene; 4,6,6,7,8,8-hexamethyl-1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene; 8,8-dimethyl-3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoinden-6-yl propionate; (Z)-6-ethylideneoctahydro-2H-5,8-methanochromen-2-one; (E)-4-((3aR,4R,7R,7aR)-1,3a,4,6,7,7a-hexahydro-5H-4,7-methanoinden-5-ylidene)-3-methylbutan-2-ol; 8,8-dimethyl-3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoinden-6-yl acetate; 3-(4-ethylphenyl)-2,2-dimethylpropanenitrile; 1-cyclopentadec-4-en-1-one; 1-cyclopentadec-4-en-1-one; Eugenyl acetate; 6-ethyl-2,10,10-trimethyl-1-oxaspiro[4.5]deca-3,6-diene; (E)-4-((3aS,7aS)-octahydro-5H-4,7-methanoinden-5-ylidene)butanal; Octahydro-1H-4,7-methanoinden-5-yl acetate; delta-Cadinene; delta-Amorphene; Decyl anthranilate; 3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoinden-6-yl butyrate; 3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoinden-5-ylisobutyrate; Curzerene; (E)-cycloheptadec-9-en-1-one; (Z)-3-methyl-2-(pent-2-en-1-yl)cyclopent-2-en-1-one; (E)-1-(2,6,6-trimethylcyclohex-2-en-1-yl)hepta-1,6-dien-3-one; (3aR,5aR,9aR,9bR)-3a,6,6,9a-tetramethyldodecahydronaphtho[2,1-b]furan; Cedryl methyl ether; Cedryl formate; Cedryl acetate; (4Z,8Z)-1,5,9-trimethyl-13-oxabicyclo[10.1.0]trideca-4,8-diene; Cedrol; 5-methyl-1-(2,2,3-trimethylcyclopent-3-en-1-yl)-6-oxabicyclo[3.2.1]octane; 1,1,2,3,3-pentamethyl-1,2,3,5,6,7-hexahydro-4H-inden-4-one; Caryophyllene alcohol acetate; Caryolan-1-ol; Bornyl isobutyrate; beta-Santalol; beta-Patchoulline; beta-Himachalene Oxide; beta-Himachalene; beta-Guaiene; (2,2-dimethoxyethyl)benzene; beta-Copaene; beta-Cedrene; beta-Caryophyllene; Bergaptene; Benzyl laurate; 2′-isopropyl-1,7,7-trimethylspiro[bicyclo[2.2.1]heptane-2,4′-[1,3]clioxane]; Anisyl phenylacetate; (3aR,5aS,9aS,9bR)-3a,6,6,9a-tetramethyldodecahydronaphtho[2,1-b]furan; (4aR,5R,7aS,9R)-2,2,5,8,8,9a-hexamethyloctahydro-4H-4a,9-methanoazuleno[5,6-d][1,3]dioxole; 2,5,5-trimethyl-1,2,3,4,5,6,7,8-octahydronaphthalen-2-ol; (3S,5aR,7aS,11aS,1 lbR)-3,8,8,11a-tetramethyldodecahydro-5H-3,5a-epoxynaphtho[2,1-c]oxepine; 2,2,6,6,7,8,8-heptamethyldecahydro-2H-indeno[4,5-b]furan; alpha-Vetivone; alpha-Santalol; alpha-Patchoulene; alpha-Muurolene; alpha-methyl ionone; alpha-Gurjunene; alpha-Eudesmol; alpha-Cubebene; alpha-Cedrene epoxide; alpha-Cadinol; alpha-Cadinene; alpha-Bisabolol; alpha-Amorphene; alpha-Agarofuran; Allo-aromadendrene; Acetoxymethyl-isolongifolene (isomers); Acetarolle; (Z)-2-(4-methylbenzylidene)heptanal; 7-eip-alpha-Eudesmol; 7-Acetyl-1,1,3,4,4,6-hexamethyltetralin; 5-Cyclohexadecenone; 4-(p-Methoxyphenyl)-2-butanone; 3-Thujopsanone; 2,6-Nonadien-1-ol; 10-epi-gamma-Eudesmol; 1,1,2,3,3-Pentamethylindan; (2S,5S,6S)-2,6,10,10-tetramethyl-1-oxaspiro[4_5]decan-6-ol; 2-(8-isopropyl-6-methylbicyclo[2.2.2]oct-5-en-2-yl)-1,3-dioxolane; 3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoinden-6-yl propionate; Bulnesol; Benzoin; 5-Acetyl-1,1,2,3,3,6-hexamethylindan; Patchouli alcohol; Perillyl alcohol; Phenethyl phenylacetate; Phenoxanol; 3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoinden-6-yl pivalate; p-Tolyl phenylacetate; (2R,4a′R,8a′R)-3,7′-dimethyl-3′,4′,4a′,5′,8′,8a′-hexahydro-1′H-spiro[oxirane-2,2′-[1,4]methanonaphthalene]; (Z)-6-ethylideneoctahydro-2H-5,8-methanochromene; 2,2,7,9-tetramethylspiro(5.5)undec-8-en-1-one; 3-methyl-5-(2,2,3-trimethylcyclopent-3-en-1-yl)pentan-2-ol; (Z)-2-ethyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)but-2-en-1-ol; 5-methoxyoctahydro-1H-4,7-methanoindene-2-carbaldehyde; Sclareol; Sclareol oxide; Selina-3,7(11)-diene; Spathulenol; 1-(spiro[4.5]dec-7-en-7-yl)pent-4-en-1-one; tau-Cadinol; tau-Muurolol; Thujopsene; 1-(2,2,6-trimethylcyclohexyl)hexan-3-ol; Tricyclone; Methyl 2-((1-hydroxy-3-phenylbutyl)amino)benzoate; Decahydro-2,6,6,7,8,8-hexamethyl-2h-indeno(4,5-b)furan; Valencene; Valerianol; 1-methoxy-3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoindene; 1-((3R,3aR,7R,8aS)-3,6,8,8-tetramethyl-2,3,4,7,8,8a-hexahydro-1H-3a,7-methanoazulen-5-yl)ethan-1-one; Methyl (Z)-2-(((2,4-dimethylcyclohex-3-en-1-yl)methylene)amino)benzoate; Vetiverol; Vetivert Acetate; Decahydro-3H-spiro[furan-2,5′-[4,7]methanoindene]; (Z)-cyclooct-4-en-1-yl methyl carbonate; (1aR,4S,4aS,7R,7aS,7bS)-1,1,4,7-tetramethyldecahydro-1H-cyclopropa[e]azulen-4-ol; 3,5,5,6,7,8,8-heptamethyl-5,6,7,8-tetrahydronaphthalene-2-carbonitrile; (1S,2S,3S,5R)-2,6,6-trimethylspiro[bicyclo[3.1.1]heptane-3,1′-cyclohexan]-2′-en-4′-one; 1′,1′,5′,5′-tetramethylhexahydro-2′H,5′H-spiro[[1,3]dioxolane-2,8′-[2,4a]methanonaphthalene]; 1′,1′,5′,5′-tetramethylhexahydro-2′H,5′H-spiro[[1,3]dioxolane-2,8′-[2,4a]methanonaphthalene] K; 4-(4-hydroxy-3-methoxyphenyl)butan-2-one; (1R,8aR)-4-isopropyl-1,6-dimethyl-1,2,3,7,8,8a-hexahydronaphthalene; 4,5-epoxy-4,11,11-trimethyl-8-methylenebicyclo(7.2.0)undecane; 1,3,4,6,7,8alpha-hexahydro-1,1,5,5-tetramethyl-2H-2,4alpha-methanophtalen-8(5H)-one; 1-(2,2-dimethyl-6-methylen cyclohexyl)-1-penten-3-one; and combinations thereof. 
     Q. A cleaning composition according to any of paragraphs A-P, wherein the one or more malodor reduction materials is selected from the group consisting of: 3-(3,3-dimethyl-2,3-dihydro-1H-inden-5-yl)propanal; 3-(6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-2,2-dimethylpropanal; 3-methyl-5-phenylpentan-1-ol; E)-3,7-dimethylocta-2,6-dien-1-yl palmitate; 3a,4,5,6,7,7a-hexahydro-4,7-methano-1H-inden-(5 and 6)-yl acetate; 3,4,4a,5,6,7,8,8a-octahydrochromen-2-one; 2,2,7,7-tetramethyltricyclo(6.2.1.0(1,6))-undecan-5-one; (E)-3,7-dimethylocta-1,3,6-triene; 1-((2-(tert-butyl)cyclohexyl)oxy)butan-2-ol; and combinations thereof. 
     R. A cleaning composition according to any of paragraphs A-Q, wherein cleaning composition further comprises a perfume. 
     S. A cleaning composition according to any of paragraphs A-R, wherein the weight ratio of parts of malodor reduction composition to parts of perfume may be from about 1:20,000 to about 3000:1, preferably from about 1:10,000 to about 1,000:1, more preferably from about 5,000:1 to about 500:1, and most preferably from about 1:15 to about 1:1. 
     T. A cleaning composition according to any of paragraphs A-S, wherein the cleaning composition further comprises from about 1% to about 80%, by weight of the cleaning composition, of a surfactant system. 
     U. A cleaning composition according to any of paragraphs A-T, wherein the surfactant system comprises an anionic surfactant, preferably selected from the group consisting of alkyl sulfate, alkyl alkoxy sulfate, alkyl benzene sulfonate, paraffin sulfonate, and mixtures thereof. 
     V. A method of cleaning a surface, preferably a textile, comprising mixing the cleaning composition according to any of paragraphs A-U with water to form an aqueous liquor and contacting a surface, preferably a textile, with the aqueous liquor in a laundering step. 
     W. The use of one or more malodor reducing materials in a cleaning composition to enhance the malodor-reducing benefits of a nuclease enzyme. 
     TEST METHODS 
     Viscosity Test Method 
     Viscosity is measured using an AR 550 rheometer/viscometer from TA instruments (New Castle, Del., USA), using parallel steel plates of 40 mm diameter and a gap size of 500 μm. The high shear viscosity at 20 s −1  is obtained from a logarithmic shear rate sweep from 0.1 s −1  to 25 s −1  in 3 minutes time at 21° C. 
     Test Method for Determining Saturation Vapour Pressure (VP) 
     The saturation Vapour Pressure (VP) values are computed for each PRM in the perfume mixture being tested. The VP of an individual PRM is calculated using the VP Computational Model, version 14.02 (Linux) available from Advanced Chemistry Development Inc. (ACD/Labs) (Toronto, Canada) to provide the VP value at 25° C. expressed in units of torr. The ACD/Labs&#39; Vapor Pressure model is part of the ACD/Labs model suite. 
     Test Method for Determining the Logarithm of the Octanol/Water Partition Coefficient (logP) 
     The value of the log of the Octanol/Water Partition Coefficient (logP) is computed for each PRM in the perfume mixture being tested. The logP of an individual PRM is calculated using the Consensus logP Computational Model, version 14.02 (Linux) available from Advanced Chemistry Development Inc. (ACD/Labs) (Toronto, Canada) to provide the unitless logP value. The ACD/Labs&#39; Consensus logP Computational Model is part of the ACD/Labs model suite. 
     Test Method for the Generation of Molecular Descriptors 
     In order to conduct the calculations involved in the computed-value test methods described herein, the starting information required includes the identity, weight percent, and molar percent of each PRM in the perfume being tested, as a proportion of that perfume, wherein all PRMs in the perfume composition are included in the calculations. Additionally for each of those PRMs, the molecular structure, and the values of various computationally-derived molecular descriptors are also required, as determined in accordance with the Test Method for the Generation of Molecular Descriptors described herein. 
     For each PRM in a perfume mixture or composition, its molecular structure is used to compute various molecular descriptors. The molecular structure is determined by the graphic molecular structure representations provided by the Chemical Abstract Service (“CAS”), a division of the American Chemical Society, Columbus, Ohio, U.S.A. These molecular structures may be obtained from the CAS Chemical Registry System database 10 by looking up the index name or CAS number of each PRM. For PRMs, which at the time of their testing are not yet listed in the CAS Chemical Registry System database, other databases or information sources may be used to determine their structures. For a PRM which has potentially more than one isomer present, the molecular descriptor computations are conducted using the molecular structure of only one of the isomers, which is selected to represent that PRM. The selection of isomer is determined by the relative amount of extension in the molecular structures of the isomers. Of all the isomers of a given PRM, it is the isomer whose molecular structure that is the most prevalent which is the one that is selected to represent that PRM. The structures for other potential isomers of that PRM are excluded from the computations. The molecular structure of the isomer that is the most prevalent is paired with the concentration of that PRM, where the concentration reflects the presence of all the isomers of that PRM that are present. 
     A molecule editor or molecular sketching software program, such as ChemDraw (CambridgeSoft/PerkinElmer Inc., Waltham, Mass., U.S.A.), is used to duplicate the 2-dimensional molecular structure representing each PRM. Molecular structures should be represented as neutral species (quaternary nitrogen atoms are allowed) with no disconnected fragments (e.g., single structures with no counter ions). The winMolconn program described below can convert any deprotonated functional groups to the neutral form by adding the appropriate number of hydrogen atoms and will discard the counter ion. 
     For each PRM, the molecular sketching software is used to generate a file which describes the molecular structure of the PRM. The file(s) describing the molecular structures of the PRMs is subsequently submitted to the computer software program winMolconn, version 1.0.1.3 (Hall Associates Consulting, Quincy, Mass., U.S.A., www.molconn.com), in order to derive various molecular descriptors for each PRM. As such, it is the winMolconn software program which dictates the structure notations and file formats that are acceptable options. These options include either a MACCS SDF formatted file (i.e., a Structure-Data File); or a Simplified Molecular Input Line Entry Specification (i.e., a SMILES string structure line notation) which is commonly used within a simple text file, often with a “.smi” or “.txt” file name extension. The SDF file represents each molecular structure in the 5 format of a multi-line record, while the syntax for a SMILES structure is a single line of text with no white space. A structure name or identifier can be added to the SMILES string by including it on the same line following the SMILES string and separated by a space, e.g.: C1=CC═CC═C1 benzene. 
     The winMolconn software program is used to generate numerous molecular descriptors for each PRM, which are then output in a table format. Specific molecular descriptors derived by winMolconn are subsequently used as inputs (i.e., as variable terms in mathematical equations) for a variety of computer model test methods in order to calculate values such as: saturation Vapour Pressure (VP); Boiling Point (BP); logarithm of the Octanol/Water Partition Coefficient (logP); Odour Detection Threshold (ODT); Malodour Reduction Value (MORV); and/or Universal Malodour Reduction Value (Universal MORV) for each PRM. The molecular descriptor labels used in the models&#39; test method computations are the same labels reported by the winMolconn program, and their descriptions and definitions can be found listed in the winMolconn documentation. The following is a generic description of how to execute the winMolconn software program and generate the required molecular structure descriptors for each PRM in a composition. 
     Computing Molecular Structure Descriptors using winMolconn:
         1) Assemble the molecular structure for one or more perfume ingredients in the form of a MACCS Structure-Data File, also called an SDF file, or as a SMILES file.   2) Using version 1.0.1.3 of the winMolconn program, running on an appropriate computer, compute the full complement of molecular descriptors that are available from the program, using the SDF or SMILES file described above as input.
           a. The output of winMolconn is in the form of an ASCII text file, typically space delimited, containing the structure identifiers in the first column and respective molecular descriptors in the remaining columns for each structure in the input file.   
           3) Parse the text file into columns using a spreadsheet software program or some other appropriate technique. The molecular descriptor labels are found on the first row of the resulting table.   4) Find and extract the descriptor columns, identified by the molecular descriptor label, corresponding to the inputs required for each model.
           a. Note that the winMolconn molecular descriptor labels are case-sensitive.   
               

     MORV and Universal MORV Calculation 
     1.) Input Molecular Descriptor values as determined via the method above into the following four equations: 
       MORV=−8.5096+2.8597·( dxp 9)+1.1253·( knotpv )−0.34484·( e 1C2O2)−10 0.00046231·( idw )+3.3509·( idcbar )+0.11158·( n 2 pag 22)  a)
 
       MORV=−5.2917+2.1741·( dxvp 5)−2.6595−( dxvp 8)+0.45297·( e 1C2C2 d )−0.6202·( c 1C2O2)+1.3542−(CdCH2)+0.68105·(CaasC)+1.7129·( idcbar )  b)
 
       MORV=−0.0035+0.8028·(SHCsatu)+2.1673·( xvp 7)−1.3507−( c 1C1C3 d )+0.61496·( c 1C1O2)+0.00403·( idc )−0.23286·( nd 2).  c)
 
       MORV=−0.9926−0.03882−(SdO)+0.1869·(Ssp3OH)+2.1847·( xp 7)+0.34344·( e 1C3O2)−0.45767·( c 1C2C3)+0.7684·(CKetone)  d)
 
     Equation a) is for the malodor trans-3-methyl-2-hexenoic acid (carboxylic acid based malodors).
 
Equation b) is for the malodor trimethylamine (amine based malodors).
 
Equation c) is for the malodor 3-mercapto-3-methylhexan-1-ol (thiol based malodors).
 
Equation d) is for the malodor skatole (indole based malodors).
 
     The program winMolconn (version 1.1.2.1) is used to compute the following set of molecular structure descriptors: c1C1C3d, c1C1O2, c1C2C3, c1C2O2, CaasC, CdCH2, CKetone, dxvp5, dxvp8, dxvp9, e1C2C2d, e1C2O2, e1C3O2, idc, idcbar, idw, knotpv, n2pag22, nd2, SdO, SHCsatu, Ssp3OH, xp7, xvp7, where c1C1C3d is a count of single bonds between a carbon atom with one double bond and two single bonds to non-hydrogen atoms (═C&lt;) and a methyl carbon atom (—CH3), c1C1O2 is a count of single bonds between 5 a methyl (—CH3) carbon atom and an oxygen atom with two single bonds, c1C2C3 is a count of single bonds between a carbon atom with three bonds to non-hydrogen atoms (&gt;CH—) and a methylene (—CH2-) carbon atom, c1C2O2 is a count of single bonds between a methylene (—CH2-) carbon atom and an oxygen atom with two single bonds, CaasC is a count of aromatic carbon atoms single-bonded to one other non-hydrogen atom, CdCH2 is a count of methylene groups (—CH2-), CKetone is account of ketone functional groups, dxvp5 is the valence-corrected difference 5th-order path molecular connectivity index, dxvp8 is the valence-corrected difference 8th-order path molecular connectivity index, dxvp9 is the valence-corrected difference 9th-order path molecular connectivity index, e1C2C2d is the sum of the bond-type electrotopological state index values for single bonds between a carbon atom with one double bond and one single bond to non-hydrogen atoms (═CH—) and a methylene (—CH2-) carbon atom, e1C2O2 is the sum of the bond-type electrotopological state index value for single bonds between a methylene (—CH2-) carbon atom and an oxygen atom with two single bonds, e1C3O2 is the sum of the bond-type electrotopological state index values for single bonds between a carbon atom with three bonds to non-hydrogen atoms (&gt;CH—) and an oxygen atom with two single bonds, idc is a Bonchev-Trinajstic information index, idcbar is a Bonchev-Trinajstic information index, idw is a Bonchev-Trinajstic information index, knotpv is the subgraph distance between xvc3 and xvpc4 where xvc3 is the valence-corrected 3rd-order molecular connectivity index and xvpc4 is the valencecorrected 4th-order path-cluster molecular connectivity index, n2pag22 is the count of path 2 subgraphs with path terminal vertex delta values of 2 and 2, nd2 is the count of vertices with a delta value of 2, SdO is the sum of the electrotopological state index values for sp2 oxygen atoms, SHCsatu is the sum of the hydrogen atom electrotopological state indexes for hydrogen atoms on sp3 carbons that are also bonded to sp2 carbon atoms, Ssp3OH is the sum of the electrotopological state index values for oxygen atoms bonded to sp3 carbon atoms, xp7 is the 7th-order path molecular connectivity index, and xvp7 is the valence-corrected 7th-order path molecular connectivity index. 
     Test Methods for Assigning Fragrance Fidelity Index (FFI) and the Blocker Index (BI) for a Malodor Reduction Compound 
     Blocker materials suitable for use in consumer products of the present invention are chosen for their ability to decrease malodor, while not interfering with perception of a fragrance. Material selection is done by assigning two indices to a test sample material from two reference scales in order to rank odor strengths. The two reference scales are the Fragrance Fidelity Index (FFI) scale and the Blocker Index (BI) scale. The FFI ranks the ability of the test sample material to impart a perceivable odor which could cause interference when combined with another fragrance and the BI ranks the ability of the test sample material to reduce malodor perception. The two methods for assigning the indices to a test sample on the FFI and the BI reference scales are given below. 
     A. Method for Assigning the FFI to Test Samples 
     The first step in the method for assigning an FFI to the test samples on the FFI reference scale is to create the FFI reference swatches. The swatches for the scale are created by treating clean fabrics swatches with a known amount of a known concentration of an ethyl vanillin solution. Fabric swatches for this test are white knit polycotton (4 inch×4 inch) swatches from EMC ordered as PC 50/50. The supplier is instructed to strip the swatches first, stripping involves washing twice with a fragrance-free detergent and rinsing three times. 
     i. Making the FFI Reference Swatches 
     Make three solutions of ethyl vanillin using a 50%/50% EtOH/water as the diluent at the following concentrations: 25 ppm, 120 ppm and 1000 ppm. Pipette 13 μL of each of the three solutions into the middle of a clean swatch resulting in about a 1 cm diameter of the solution in the middle of the swatch. This will create a sensory scale of three swatches with three different odor levels based on the concentration of the solution pipetted onto the swatch. After drying for 30 minutes in a vented hood, the swatches are wrapped in aluminum foil to prevent odor contamination to the treated swatch. A clean untreated swatch is also included as the lowest anchor point of reference for odor strength on the FFI scale. The FFI reference scale swatches should be used within 0.5 to 12 hours and discarded after 12 hours. The swatches are used as scale anchor points when graders evaluate a test sample(s) and are assigned a Fragrance Fidelity Index (FFI) as show in Table W. 
     At least four perfumers/expert graders are used to rank the ethyl vanillin swatches in the FFI scale. The perfumer/expert grader needs to demonstrate adequate discrimination on the scale. The perfumer/expert panel is asked to rank order swatches according to a scale between 0 and 3. The panel must demonstrate statistical differences between the swatches. 
     
       
         
           
               
             
               
                 TABLE W 
               
             
            
               
                   
               
               
                 Results FFI of reference swatches from six perfumers/expert graders. 
               
            
           
           
               
               
               
            
               
                   
                 Expert Grader 
                   
               
            
           
           
               
               
               
               
               
               
               
               
               
               
            
               
                 FFI 
                 Swatch 
                 1 
                 2 
                 3 
                 4 
                 5 
                 6 
                 Ave 
                 Std Dev. 
               
               
                   
               
            
           
           
               
               
               
               
               
               
               
               
               
               
            
               
                 0 
                 Control: stripped swatch NIL 
                 0 
                 0 
                 0.5 
                 0 
                 0 
                 0 
                 0.08 
                 0.2 
               
               
                   
                 ethyl vanillin 
               
               
                 1 
                 Stripped swatch with 13 μL 25 ppm 
                 0.5 
                 0.5 
                 0.5 
                 1.5 
                 0.5 
                 1.0 
                 0.75 
                 0.4 
               
               
                   
                 ethyl vanillin 
               
               
                 2 
                 Stripped swatch with 13 μL 
                 2.0 
                 1.5 
                 1.5 
                 2.0 
                 2.0 
                 2.0 
                 1.8 
                 0.2 
               
               
                   
                 120 ppm ethyl vanillin 
               
               
                 3 
                 Stripped swatch with 13 μL 
                 3.0 
                 2.0 
                 3.0 
                 3.0 
                 3.0 
                 3.0 
                 2.8 
                 0.4 
               
               
                   
                 1000 ppm ethyl vanillin 
               
               
                   
               
            
           
         
       
     
     The expert graders must demonstrate a full range of 2.5 over the 4 swatches to be acceptably discriminating. Grader 2 in table W has a range of only 2 and is eliminated from the panel. The panel of expert graders must also demonstrated the ability to statistically discriminate between swatches in the scale. 
     
       
         
           
               
             
               
                 TABLE X 
               
             
            
               
                   
               
               
                 This table demonstrates acceptable expert graders with an acceptable 
               
               
                 range and the panel meets the requirement for discriminating statistics. 
               
            
           
           
               
               
               
            
               
                   
                 Expert Grader 
                   
               
            
           
           
               
               
               
               
               
               
               
               
               
            
               
                 FFI 
                 Swatch 
                 1 
                 3 
                 4 
                 5 
                 6 
                 Ave 
                 Std Dev. 
               
               
                   
               
            
           
           
               
               
               
               
               
               
               
               
               
            
               
                 0 
                 Control: stripped 
                 0 
                 0.5 
                 0 
                 0 
                 0 
                 0.08 
                 0.2 
               
               
                   
                 swatch NIL 
               
               
                   
                 ethyl vanillin 
               
               
                 1 
                 Stripped swatch with 
                 0.5 
                 0.5 
                 1.5 
                 0.5 
                 1.0 
                 0.80 
                 0.4 
               
               
                   
                 13 μL 25 ppm 
               
               
                   
                 ethyl vanillin 
               
               
                 2 
                 Stripped swatch with 
                 2.0 
                 1.5 
                 2.0 
                 2.0 
                 2.0 
                 1.9 
                 0.2 
               
               
                   
                 13 μL 120 
               
               
                   
                 ppm ethyl vanillin 
               
               
                 3 
                 Stripped swatch with 
                 3.0 
                 3.0 
                 3.0 
                 3.0 
                 3.0 
                 3.0 
                 0.0 
               
               
                   
                 13 μL 1000 ppm 
               
               
                   
                 ethyl vanillin 
               
               
                   
               
            
           
         
       
     
     The reference swatches represent the 0, 1, 2, and 3 FFIs on the FFI reference scale, Table Y. The expert grader should familiarize them self with the strength of the odor on the FFI reference swatches by sniffing each one starting at 0 (the lowest odor strength) and ending at 3 (the highest odor strength). This should be done prior to evaluating the test sample material treated swatch. 
     
       
         
           
               
             
               
                 TABLE Y 
               
             
            
               
                   
               
               
                 Swatch treatments comprising the 
               
               
                 Fragrance Fidelity Index (FFI) reference scale 
               
            
           
           
               
               
               
            
               
                 Swatch treatment 
                 Conc. of ethyl vanillin 
                 FFI 
               
               
                   
               
            
           
           
               
               
               
            
               
                 Clean fabric swatch w/ 13 μL 
                 1000 ppm ethyl vanillin 
                 3 
               
               
                 ethyl vanillin 
               
               
                 Clean fabric swatch w/ 13 μL 
                  120 ppm ethyl vanillin 
                 2 
               
               
                 ethyl vanillin 
               
               
                 Clean fabric swatch w/ 13 μL 
                  25 ppm ethyl vanillin 
                 1 
               
               
                 ethyl vanillin 
               
               
                 Clean fabric swatch NIL ethyl vanillin 
                 NIL ethyl vanillin 
                 0 
               
               
                   
               
            
           
         
       
     
     ii. Making Swatches Treated with the Test Material 
     A clean swatch is treated with 13 μL of a known concentration of a test sample material resulting in an about 1 cm of the solution on the clean swatch. Just like the reference swatches, the test sample material swatch is dried in a vented hood for 30 minutes and then wrapped in aluminum foil to prevent contamination. The test material swatches and the FFI reference swatches should be made within 2 hrs of each other. The test material swatch must be used within 0.5 to 12 hours and discarded after 12 hours. 
     iii. Assigning the FFI to the Test Material 
     At least two perfumers/expert graders are used to assign an FFI grade to a test sample. The perfumer/expert grader smells the test sample swatch by holding that swatch 1 inch from their nose with their nose centered over the area where the test sample was pipetted on to the fabric and then assigns the test sample an FFI grade using the FFI reference scale anchor swatches as references. The test sample swatch is assigned an FFI grade at or between numbers on the FFI scale shown in Table 9. In cases where the test sample material is graded greater than 3, the test material is not a blocker material or the concentration of the material needs to be lowered and reevaluated to determine if a lower level has a malodor blocker functionality. 
     B. Method for Assigning the BI to Test Sample 
     The first step in the method for assigning a BI to a test sample material on the BI reference scale is to create the BI reference swatches. The swatches for the scale are created by treating clean fabrics swatches with a known amount of a known volume of isovaleric acid solution at a known concentration. Fabric swatches for this test are white knit polycotton (4 inch×4 inch) swatches from EMC ordered as PC 50/50. The supplier is instructed to strip the swatches first, stripping involves washing twice with a fragrance-free detergent and rinsing three times. 
     i. Making the BI Reference Swatches 
     Make one solution of 0.08% isovaleric acid using 50%/50% EtOH/water as the diluent. The BI scale contains one clean swatch with no malodor applied. Three other swatches each have a different volume of the 0.08% isovaleric acid applied. Pipette 2 μL of the 0.08% isovaleric acid solution to one clean swatch, 5 μL of the 0.08% isovaleric acid solution to the next swatch and 20 μL of isovaleric acid to the final clean swatch. These solutions are pipetted to the middle of the swatches. This will create a sensory scale of three swatches with three different odor levels based on the volume of the 0.08% isovaleric acid solution pipetted onto the swatch. After drying for 30 minutes in a vented hood, the swatches are wrapped in aluminum foil to prevent odor contamination to the treated swatch. A clean untreated swatch is also included as the lowest anchor point of reference for malodor strength on the BI scale. The BI reference scale swatches should be used within 0.5 to 12 hours and discarded after 12 hours. The swatches are used as scale anchor points when graders evaluate a test sample(s) and are assigned a Blocker Index (BI). The reference swatches represent the 0, 1, 2, and 3 BIs on the BI reference scale, Table 12. The expert grader should familiarizes him/herself with the strength of the odor on the BI reference swatches by sniffing each one starting at 0 (the lowest odor strength) and ending at 3 (the highest odor strength). This should be done prior to evaluating the swatch treated with the test material. 
     
       
         
           
               
             
               
                 TABLE Z 
               
             
            
               
                   
               
               
                 Swatch treatments comprising the Blocker Index (BI) reference scale. 
               
            
           
           
               
               
               
            
               
                 Swatch/treatment 
                 Wt of isovaleric acid 
                 BI 
               
               
                   
               
               
                 Clean fabric swatch w/ 20 μL 
                  16 mg isovaleric acid 
                 3 
               
               
                 0.08% isovaleric acid 
               
               
                 Clean fabric swatch w/ 5 μL 
                   4 mg isovaleric acid 
                 2 
               
               
                 0.08% isovaleric acid 
               
               
                 Clean fabric swatch w/ 2 μL 
                 1.6 mg isovaleric acid 
                 1 
               
               
                 0.08% isovaleric acid 
               
               
                 Clean fabric swatch NIL isovaleric acid 
                 NIL isovaleric acid 
                 0 
               
               
                   
               
            
           
         
       
     
     At least four perfumers/expert graders are used to rank the isovaleric acid swatches in the BI scale. The perfumer/expert grader needs to demonstrate adequate discrimination on the scale. The perfumer/expert grader is asked to rank order swatches according to a scale between 0 and 3. The panel of graders must demonstrate statistical differences between the swatches. 
     Making the Malodorous Swatch and Treating it with a Test Material 
     To evaluate the BI, the test material is applied to a malodorous swatch to determine how well the test material blocks the malodor. The malodorous swatch is made by treating a clean swatch with 20 μL of a 0.08% solution of isovaleric acid. Dry the malodorous swatch treated with isovaleric acid in a vented hood for 30 minutes. After drying the malodorous swatch a known concentration of test material solution, between 1 ppm and 100 ppm is pipetted onto the malodorous swatch. Apply the test material solution right on top of the spot where the isovaleric acid solution was applied making an about 1 cm diameter spot. Just like the BI reference swatches, the isovaleric acid+test material swatch is dried in a vented hood for 30 minutes and then wrapped in aluminum foil to prevent contamination. The isovaleric acid+test material swatches and the BI reference swatches should be made within 2 hrs of each other. The isovaleric acid+test material swatch must be used between 1-12 hours just like the reference swatches. It is sometimes necessary to evaluate several levels of the test material between about 1 and about 100 ppm to determine the BI. 
     ii. Assigning the BI to the Test Material 
     At least two perfumers/expert graders are used to assign the BI to the test sample. The expert grader smells the isovaleric acid+test material swatch by holding that swatch one inch from their nose with their nose centered over the area where the test sample was pipetted on to the fabric and then assigns the isovaleric acid+test material swatch a BI based on ranking its odor strength against the odor strength of the swatches in the BI reference scale. The test sample swatch is assigned a BI at or between numbers on the BI in table. In cases where the isovaleric acid+test material swatch odor is greater than 3 on the BI reference scale, this indicates the material is not a blocker or the concentration of the test material needs to be lowered to achieve its blocker functionality. 
     EXAMPLES 
     The following are illustrative examples of cleaning compositions of the invention and are not intended to be limiting. 
     Example 1—Compositions Comprising Malodor Reduction Compounds 
     In the present disclosure, blends enable more potent malodor reduction because blends are useful at a higher % of the product composition before becoming olfactively noticeable. Below are non-limiting examples of malodor reduction compounds and blends (A-E). 
     
       
         
           
               
               
            
               
                   
                   
               
               
                   
                 % wt Active 
               
            
           
           
               
               
               
               
               
               
               
            
               
                 Component 
                 CAS# 
                 A 
                 B 
                 C 
                 D 
                 E 
               
               
                   
               
               
                 2,2,8,8-tetramethyl-octahydro-1H- 
                 29461-14-1 
                 35-45 
                 15-25 
                 5-20 
                 10-30 
                 15-25 
               
               
                 2,4a-methanonapthalene-10-one 
               
               
                 1H-Indene-ar-propanal,2,3- 
                 300371-33-9 
                 10-20 
                  1-30 
                 NIL 
                  5-10 
                 1-5 
               
               
                 dihydro-1,1-dimethyl- 
               
               
                 Hexadecanoic acid, (2E)-3,7- 
                 3681-73-0 
                 35-45 
                 10-25 
                 NIL 
                 30-40 
                 35-50 
               
               
                 dimethyl-2,6-octadien-1-yl ester 
               
               
                 1-Pentanol-3-methyl-5-phenyl 
                 55066-48-3 
                 10-20 
                 10-25 
                  2-10 
                  5-17 
                 10 
               
               
                 4,7-Methano-1H-inden-5-ol, 
                 171102-41-3 
                 0-5 
                 10-25 
                 NIL 
                 1-6 
                 1-5 
               
               
                 3a,4,5,6,7,7a-hexahydro-, 5-acetate 
               
               
                 4,8-dimethyl-1-(methylethyl)-7- 
                 N/A 
                 0-5 
                 NIL 
                 NIL 
                 NIL 
                 1-5 
               
               
                 oxybiciclo [4.3.0]nonane 
               
               
                 (3Z)-3,7-dimethylocta-1,3,6-triene 
                 3338-55-4 
                 NIL 
                 NIL 
                 10-20 
                 2-5 
                 NIL 
               
               
                 1H-Indene-5-propanal, 2,3- 
                 173445-65-3 
                 NIL 
                 NIL 
                 NIL 
                 7.5-16  
                  1-15 
               
               
                 dihydro-3,3-dimethyl- 
               
               
                 3,4,4a,5,6,7,8,8a- 
                 4430-31-3 
                 NIL 
                 NIL 
                 NIL 
                 3-7 
                  1-15 
               
               
                 octahydrochromen-2-one 
               
               
                 1-(2-tert- 
                 139504-68-0 
                 NIL 
                 NIL 
                 NIL 
                 0.25-1.5  
                 NIL 
               
               
                 butylcyclohexyl)oxybutan-2-ol 
               
               
                 ethyl (2,3,6-trimethylcyclohexyl)carbonate 
                 93981-50-1 
                 NIL 
                 NIL 
                 15-30 
                 NIL 
                  2 
               
               
                 benzyl 2-hydroxypropanoate 
                 2051-96-9 
                 NIL 
                 NIL 
                 2-5 
                 NIL 
                 NIL 
               
               
                 (3,5-dimethylcyclohex-3-en-1- 
                 67634-16-6 
                 NIL 
                 NIL 
                  5-30 
                 NIL 
                 NIL 
               
               
                 yl)methanol 
               
               
                 2-Dodecanol 
                 10203-28-8 
                 NIL 
                 0.25-1   
                 NIL 
                 0.5-3   
                 NIL 
               
               
                   
               
            
           
         
       
     
     Example 2—Compositions Comprising Malodor Reduction Compounds 
     Below are non-limiting examples of malodor reduction compounds and blends (F-K). 
     
       
         
           
               
               
            
               
                   
                   
               
               
                   
                 % wt Active 
               
            
           
           
               
               
               
               
               
               
               
               
            
               
                 Ingredient 
                 CAS # 
                 F 
                 G 
                 H 
                 I 
                 J 
                 K 
               
               
                   
               
            
           
           
               
               
               
               
               
               
               
               
            
               
                 (E)-1-(2,6,6-trimethyl-1- 
                 127-42-4 
                 4 
                 8 
                 2 
                 8 
                 3 
                 2 
               
               
                 cyclohex-2-enyl)pent-1-en-3- 
               
               
                 one 
               
               
                 ethyl dodecanoate 
                 106-33-2 
                 NIL 
                 1 
                 NIL 
                 3 
                 NIL 
                 NIL 
               
               
                 3a,4,5,6,7,7a-hexahydro-1H- 
                 68912-13-0 
                 8 
                 30 
                 1 
                 4 
                 1 
                 3.5 
               
               
                 4,7-methanoinden-1-yl 
               
               
                 propanoate 
               
               
                 [1R-(1R*,4R*,6R*,10S*)]- 
                 1139-30-6 
                 NIL 
                 0.3 
                 2 
                 0.5 
                 NIL 
                 0.5 
               
               
                 4,12,12-trimethyl-9- 
               
               
                 methylene-5- 
               
               
                 oxatricyclo[8.2.0.04,6]dodecane 
               
               
                 (8E)-cyclohexadec-8-en-1-one 
                 3100-36-5 
                 NIL 
                 5 
                 NIL 
                 7 
                 NIL 
                 NIL 
               
               
                 3,5,5-trimethylhexyl acetate 
                 58430-94-7 
                 25 
                 15 
                 50 
                 35 
                 60 
                 56 
               
               
                 ethyl (2,3,6- 
                 93981-50-1 
                 NIL 
                 1 
                 NIL 
                 5 
                 NIL 
                 NIL 
               
               
                 trimethylcyclohexyl)carbonate 
               
               
                 2,4-dimethyl-4,4a,5,9b- 
                 27606-09-3 
                 25 
                 10 
                 15 
                 15 
                 16 
                 15 
               
               
                 tetrahydroindeno[1,2- 
               
               
                 d][1,3]dioxine 
               
               
                 2,2,7,7- 
                 23787-90-8 
                 8 
                 9 
                 5 
                 7 
                 5 
                 5 
               
               
                 tetramethyltricyclo[6.2.1.01,6] 
               
               
                 undecan-5-one 
               
               
                 (3,5-dimethylcyclohex-3-en- 
                 67634-16-6 
                 NIL 
                 0.7 
                 NIL 
                 0.5 
                 NIL 
                 NIL 
               
               
                 1-yl)methanol 
               
               
                 3-(7,7-dimethyl-4- 
                 33885-52-8 
                 30 
                 20 
                 25 
                 15 
                 15 
                 18 
               
               
                 bicyclo[3.1.1]hept-3-enyl)- 
               
               
                 2,2-dimethylpropanal 
                   
                   
               
               
                 Total 
                   
                 100 
                 100 
                 100 
                 100 
                 100 
                 100 
               
               
                   
               
            
           
         
       
     
     Example 3—Malodor Reduction Composition 
     Below in are non-limiting examples of malodor reduction compounds and blends (L-N). 
     
       
         
           
               
               
            
               
                   
                   
               
               
                   
                 % wt Active 
               
            
           
           
               
               
               
               
               
            
               
                 Ingredient 
                 CAS # 
                 L 
                 M 
                 N 
               
               
                   
               
            
           
           
               
               
               
               
               
            
               
                 5-Cyclohexadecen-1-One 
                 37609-25-9 
                 15.0 
                 2.00 
                 2.00 
               
               
                 decahydro-2,2,7,7,8,9,9- 
                 476332-65-7 
                 0.005 
                 0.01 
                 0.01 
               
               
                 heptamethylindeno(4,3a- 
               
               
                 b)furan 
               
               
                 2,3-Dihydro-5,6-dimethoxy- 
                 33704-61-9 
                 0.3 
                 0.5 
                 0.5 
               
               
                 2-(4-piperidinylmethylene)- 
               
               
                 1H-inden-1-one 
               
               
                 Cedryl Methyl Ether 
                 19870-74-7 
                 6.0 
                 10.0 
                 4.0 
               
               
                 Trans-4-Decenal 
                 65405-70-1 
                 0.005 
                 0.002 
                 0.002 
               
               
                 Decyl Aldehyde 
                 112-31-2 
                 3.74 
                 2.0 
                 2.0 
               
               
                 3-methyl cyclopentadecenone 
                 63314-79-4 
                 0.4 
                 1.0 
                 1.0 
               
               
                 Diphenyl Oxide 
                 101-84-8 
                 0.5 
                 1.0 
                 1.0 
               
               
                 3a,4,5,6,7,7a-hexahydro-4,7- 
                 54830-99-8 
                 5.0 
                 8.0 
                 8.0 
               
               
                 methano-1H-indenyl acetate 
               
               
                 3a,4,5,6,7,7a-hexahydro- 
                 68912-13-0 
                 6.0 
                 8.0 
                 8.0 
               
               
                 1H-4,7-methanoinden- 
               
               
                 1-yl propanoate 
               
               
                 2-(5-methyl-2-propan-2-yl-8- 
                 68901-32-6 
                 10.0 
                 15.0 
                 15.0 
               
               
                 bicyclo[2.2.2]oct-5-enyl)- 
               
               
                 1,3-dioxolane 
               
               
                 (E)-3,7-dimethyl-2,6- 
                 3681-73-0 
                 10.0 
                 10.0 
                 16.0 
               
               
                 octadienylhexadecanoate 
               
               
                 Iso Nonyl Acetate 
                 58430-94-7 
                 6.65 
                 8.0 
                 3.0 
               
               
                 2,2,7,7- 
                 23787-90-8 
                 10.0 
                 8.0 
                 8.0 
               
               
                 tetramethyltricyclo[6.2.1.01, 
               
               
                 6]undecan-5-one 
               
               
                 (1-Methyl-2-(1,2,2- 
                 198404-98-7 
                 0.1 
                 0.3 
                 0.3 
               
               
                 trimethylbicyclo[3.1.0]-hex-3- 
               
               
                 ylmethyl)cyclopropyl) 
               
               
                 methanol 
               
               
                 Lauric Aldehyde 
                 112-54-9 
                 0.625 
                 1.0 
                 0.7 
               
               
                 Methyl Iso Eugenol 
                 93-16-3 
                 18.000 
                 10.0 
                 13.0 
               
               
                 Methyl hexadecanoate 
                 112-39-0 
                 3.000 
                 10.0 
                 12.0 
               
               
                 2,3-dihydro-1,1-1H-dimethyl- 
                 300371-33-9 
                 0.400 
                 0.0 
                 0.3 
               
               
                 indene-ar-propanal 
               
               
                 4-tert-butylcyclohexanol 
                 98-52-2 
                 0.400 
                 0.1 
                 0.1 
               
               
                 2-isobutyl-4-hydroxy-4- 
                 63500-71-0 
                 1.600 
                 2.0 
                 2.0 
               
               
                 methyltetrahydropyran 
               
               
                 Undecyl Aldehyde 
                 112-44-7 
                 1.725 
                 2.888 
                 1.888 
               
               
                 Undecylenic Aldehyde 
                 112-45-8 
                 0.550 
                 0.2 
                 1.2 
               
               
                 Total 
                   
                 100 
                 100.0 
                 100.0 
               
               
                   
               
            
           
         
       
     
     Example 4—Malodor Reducting Composition 
     Below are non-limiting examples of malodor reduction compounds and blends (O-P). 
     
       
         
           
               
               
            
               
                   
                   
               
               
                   
                 Weight % 
               
            
           
           
               
               
               
               
            
               
                   
                 CAS# 
                 O 
                 P 
               
               
                   
                   
               
            
           
           
               
               
               
               
            
               
                 3-(3,3-dimethyl-2,3-dihydro-1H- 
                 300371-33-9 
                 7.500 
                 1.000 
               
               
                 inden-5-yl)propanal 
               
               
                 3-(6,6-dimethylbicyclo[3.1.1]hept- 
                 33885-52-8 
                 10.000 
                 NIL 
               
               
                 2-en-2-yl)-2,2-dimethylpropanal 
               
               
                 3-methyl-5-phenylpentan-1-ol 
                 55066-48-3 
                 10.000 
                 49.000 
               
               
                 E)-3,7-dimethylocta-2,6-dien-1-yl 
                 3681-73-0 
                 40.000 
                 20.000 
               
               
                 palmitate 
               
               
                 3a,4,5,6,7,7a-hexahydro-4,7- 
                 5413-60-5 
                 4.000 
                 15.000 
               
               
                 methano-1H-inden-(5 and 6)-yl 
               
               
                 acetate 
               
               
                 3,4,4a,5,6,7,8,8a- 
                 4430-31-3 
                 5.000 
                 NIL 
               
               
                 octahydrochromen-2-one 
               
               
                 2,2,7,7- 
                 23787-90-8 
                 20.000 
                 5.000 
               
               
                 tetramethyltricyclo(6.2.1.0(1,6))- 
               
               
                 undecan-5-one 
               
               
                 (E)-3,7-dimethylocta-1,3,6-triene 
                 3338-55-4 
                 3.000 
                 NIL 
               
               
                 1-((2-(tert- 
                 139504-68-0 
                 0.500 
                 10.000 
               
               
                 butyl)cyclohexyl)oxy)butan-2-ol 
                   
               
               
                 Total 
                   
                 100.000 
                 100.000 
               
               
                   
               
            
           
         
       
     
     The following are examples of cleaning compositions according to the present disclosure. 
     Example 5—Heavy Duty Liquid Laundry Detergent Compositions 
       
     
       
         
           
               
               
               
               
               
               
               
               
            
               
                   
                   
               
               
                   
                 1 
                 2 
                 3 
                 4 
                 5 
                 6 
                 7 
               
            
           
           
               
               
            
               
                 Ingredients 
                 % weight 
               
               
                   
               
            
           
           
               
               
               
               
               
               
               
               
            
               
                 AE 1.8 S 
                 6.77 
                 5.16 
                 1.36 
                 1.30 
                 — 
                 — 
                 — 
               
               
                 AE 3 S 
                 — 
                 — 
                 — 
                 — 
                 0.45 
                 — 
                 — 
               
               
                 LAS 
                 0.86 
                 2.06 
                 2.72 
                 0.68 
                 0.95 
                 1.56 
                 3.55 
               
               
                 HSAS 
                 1.85 
                 2.63 
                 1.02 
                 — 
                 — 
                 — 
                 — 
               
               
                 AE9 
                 6.32 
                 9.85 
                 10.20  
                 7.92 
               
               
                 AE8 
                   
                   
                   
                   
                   
                   
                 35.45  
               
               
                 AE7 
                   
                   
                   
                   
                 8.40 
                 12.44  
               
               
                 C 12-14  dimethyl Amine Oxide 
                 0.30 
                 0.73 
                 0.23 
                 0.37 
                 — 
                 — 
                 — 
               
               
                 C 12-18  Fatty Acid 
                 0.80 
                 1.90 
                 0.60 
                 0.99 
                 1.20 
                 — 
                 15.00  
               
               
                 Citric Acid 
                 2.50 
                 3.96 
                 1.88 
                 1.98 
                 0.90 
                 2.50 
                 0.60 
               
               
                 Optical Brightener 1 
                 1.00 
                 0.80 
                 0.10 
                 0.30 
                 0.05 
                 0.50 
                  0.001 
               
               
                 Optical Brightener 3 
                  0.001 
                 0.05 
                 0.01 
                 0.20 
                 0.50 
                 — 
                 1.00 
               
               
                 Sodium formate 
                 1.60 
                 0.09 
                 1.20 
                 0.04 
                 1.60 
                 1.20 
                 0.20 
               
               
                 DTI 1 
                 0.32 
                 0.05 
                 — 
                 0.60 
                 0.10 
                 0.60 
                 0.01 
               
               
                 DTI 2 
                 0.32 
                 0.10 
                 0.60 
                 0.60 
                 0.05 
                 0.40 
                 0.20 
               
               
                 Sodium hydroxide 
                 2.30 
                 3.80 
                 1.70 
                 1.90 
                 1.70 
                 2.50 
                 2.30 
               
               
                 Monoethanolamine 
                 1.40 
                 1.49 
                 1.00 
                 0.70 
                 — 
                 — 
                 — 
               
               
                 Diethylene glycol 
                 5.50 
                 — 
                 4.10 
                 — 
                 — 
                 — 
                 — 
               
               
                 Chelant 1 
                 0.15 
                 0.15 
                 0.11 
                 0.07 
                 0.50 
                 0.11 
                 0.80 
               
               
                 4-formyl-phenylboronic acid 
                 — 
                 — 
                 — 
                 — 
                 0.05 
                 0.02 
                 0.01 
               
               
                 Sodium tetraborate 
                 1.43 
                 1.50 
                 1.10 
                 0.75 
                 — 
                 1.07 
                 — 
               
               
                 Ethanol 
                 1.54 
                 1.77 
                 1.15 
                 0.89 
                 — 
                 3.00 
                 7.00 
               
               
                 Polymer 1 
                 0.10 
                 — 
                 — 
                 — 
                 — 
                 — 
                 2.00 
               
               
                 Polymer 2 
                 0.30 
                 0.33 
                 0.23 
                 0.17 
                 — 
                 — 
                 — 
               
               
                 Polymer 3 
                 — 
                 — 
                 — 
                 — 
                 — 
                 — 
                 0.80 
               
               
                 Polymer 4 
                 0.80 
                 0.81 
                 0.60 
                 0.40 
                 1.00 
                 1.00 
                 — 
               
               
                 1,2-Propanediol 
                 — 
                 6.60 
                 — 
                 3.30 
                 0.50 
                 2.00 
                 8.00 
               
               
                 Structurant 
                 0.10 
                 — 
                 — 
                 — 
                 — 
                 — 
                 0.10 
               
               
                 Perfume 
                 1.60 
                 1.10 
                 1.00 
                 0.80 
                 0.90 
                 1.50 
                 1.60 
               
               
                 Perfume encapsulate 
                 0.10 
                 0.05 
                 0.01 
                 0.02 
                 0.10 
                 0.05 
                 0.10 
               
               
                 Malodour reduction material(s) 
                 0.10 
                 0.05 
                 0.01 
                 0.02 
                 0.10 
                 0.05 
                 0.10 
               
               
                 Protease 
                 0.80 
                 0.60 
                 0.70 
                 0.90 
                 0.70 
                 0.60 
                 1.50 
               
               
                 Mannanase 
                 0.07 
                 0.05 
                  0.045 
                 0.06 
                 0.04 
                  0.045 
                 0.10 
               
               
                 Amylase 1 
                 0.30 
                 — 
                 0.30 
                 0.10 
                 — 
                 0.40 
                 0.10 
               
               
                 Amylase 2 
                 — 
                 0.20 
                 0.10 
                 0.15 
                 0.07 
                 — 
                 0.10 
               
               
                 Xyloglucannase 
                 0.20 
                 0.10 
                 — 
                 — 
                 0.05 
                 0.05 
                 0.20 
               
               
                 Lipase 
                 0.40 
                 0.20 
                 0.30 
                 0.10 
                 0.20 
                 — 
                 — 
               
               
                 Polishing enzyme 
                 — 
                 0.04 
                 — 
                 — 
                 — 
                  0.004 
                 — 
               
               
                 Nuclease 
                 0.05 
                 0.03 
                 0.01 
                 0.03 
                 0.03 
                  0.003 
                  0.003 
               
               
                 Dispersin B 
                 — 
                 — 
                 — 
                 0.05 
                 0.03 
                  0.001 
                  0.001 
               
               
                 Acid Violet 50 
                 0.05 
                 — 
                 — 
                 — 
                 — 
                 — 
                  0.005 
               
               
                 Direct Violet 9 
                 — 
                 — 
                 — 
                 — 
                 — 
                 0.05 
                 — 
               
               
                 Violet DD 
                 — 
                  0.035 
                 0.02 
                  0.037 
                 0.04 
                 — 
                 — 
               
            
           
           
               
               
            
               
                 Water, dyes &amp; minors 
                 Balance 
               
               
                 pH 
                 8.2 
               
               
                   
               
               
                 Based on total cleaning and/or treatment composition weight. Enzyme levels are reported as raw material. 
               
            
           
         
       
     
     Example 6—Unit Dose Compositions 
     These examples provide various formulations for unit dose laundry detergents. Compositions 8 to 12 comprise a single unit dose compartment. The film used to encapsulate the compositions includes polyvinyl alcohol. 
     
       
         
           
               
               
               
               
               
               
            
               
                   
                   
               
               
                   
                 8 
                 9 
                 10 
                 11 
                 12 
               
            
           
           
               
               
            
               
                 Ingredients 
                 % weight 
               
               
                   
               
            
           
           
               
               
               
               
               
               
            
               
                 LAS 
                 19.09 
                 16.76 
                 8.59 
                 6.56 
                 3.44 
               
               
                 AE3S 
                 1.91 
                 0.74 
                 0.18 
                 0.46 
                 0.07 
               
               
                 AE7 
                 14.00 
                 17.50 
                 26.33 
                 28.08 
                 31.59 
               
               
                 Citric Acid 
                 0.6 
                 0.6 
                 0.6 
                 0.6 
                 0.6 
               
               
                 C12-15 Fatty Acid 
                 14.8 
                 14.8 
                 14.8 
                 14.8 
                 14.8 
               
               
                 Polymer 3 
                 4.0 
                 4.0 
                 4.0 
                 4.0 
                 4.0 
               
               
                 Chelant 2 
                 1.2 
                 1.2 
                 1.2 
                 1.2 
                 1.2 
               
               
                 Optical Brightener 1 
                 0.20 
                 0.25 
                 0.01 
                 0.01 
                 0.50 
               
               
                 Optical Brightener 2 
                 0.20 
                 — 
                 0.25 
                 0.03 
                 0.01 
               
               
                 Optical Brightener 3 
                 0.18 
                 0.09 
                 0.30 
                 0.01 
                 — 
               
               
                 DTI 1 
                 0.10 
                 — 
                 0.20 
                 0.01 
                 0.05 
               
               
                 DTI 2 
                 — 
                 0.10 
                 0.20 
                 0.25 
                 0.05 
               
               
                 Glycerol 
                 6.1 
                 6.1 
                 6.1 
                 6.1 
                 6.1 
               
               
                 Monoethanol amine 
                 8.0 
                 8.0 
                 8.0 
                 8.0 
                 8.0 
               
               
                 Tri-isopropanol amine 
                 — 
                 — 
                 2.0 
                 — 
                 — 
               
               
                 Tri-ethanol amine 
                 — 
                 2.0 
                 — 
                 — 
                 — 
               
               
                 Cumene sulfonate 
                 — 
                 — 
                 — 
                 — 
                 2.0 
               
               
                 Protease 
                 0.80 
                 0.60 
                 0.07 
                 1.00 
                 1.50 
               
               
                 Mannanase 
                 0.07 
                 0.05 
                 0.05 
                 0.10 
                 0.01 
               
               
                 Amylase 1 
                 0.20 
                 0.11 
                 0.30 
                 0.50 
                 0.05 
               
               
                 Amylase 2 
                 0.11 
                 0.20 
                 0.10 
                 — 
                 0.50 
               
               
                 Polishing enzyme 
                 0.005 
                 0.05 
                 — 
                 — 
                 — 
               
               
                 Nuclease 
                 0.005 
                 0.05 
                 0.005 
                 0.010 
                 0.005 
               
               
                 Dispersin B 
                 0.010 
                 0.05 
                 0.005 
                 0.005 
                 — 
               
               
                 Cyclohexyl dimethanol 
                 — 
                 — 
                 — 
                 2.0 
                 — 
               
               
                 Acid violet 50 
                 0.03 
                 0.02 
               
               
                 Violet DD 
                   
                   
                 0.01 
                 0.05 
                 0.02 
               
               
                 Structurant 
                 0.14 
                 0.14 
                 0.14 
                 0.14 
                 0.14 
               
               
                 Perfume 
                 1.9 
                 1.9 
                 1.9 
                 1.9 
                 1.9 
               
               
                 Malodour reduction 
                 0.9 
                 0.03 
                 0.05 
                 0.1 
                 0.005 
               
               
                 material(s) 
               
            
           
           
               
               
            
               
                 Water and miscellaneous 
                 To 100% 
               
               
                 pH 
                 7.5-8.2 
               
               
                   
               
               
                 Based on total cleaning and/or treatment composition weight. Enzyme levels are reported as raw material. 
               
            
           
         
       
     
     In the following examples the unit dose has three compartments, but similar compositions can be made with two, three, four or five compartments. The film used to encapsulate the compartments includes polyvinyl alcohol. 
     
       
         
           
               
               
               
               
               
             
               
                   
               
             
            
               
                 Base compositions 
                 13 
                 14 
                 15 
                 16 
               
            
           
           
               
               
            
               
                 Ingredients 
                 % weight 
               
               
                   
               
            
           
           
               
               
               
               
               
            
               
                 HLAS 
                 26.82 
                 16.35 
                 7.50 
                 3.34 
               
               
                 AE7 
                 17.88 
                 16.35 
                 22.50 
                 30.06 
               
               
                 Citric Acid 
                 0.5 
                 0.7 
                 0.6 
                 0.5 
               
               
                 C12-15 Fatty acid 
                 16.4 
                 6.0 
                 11.0 
                 13.0 
               
               
                 Polymer 1 
                 2.9 
                 0.1 
                 — 
                 — 
               
               
                 Polymer 3 
                 1.1 
                 5.1 
                 2.5 
                 4.2 
               
               
                 Cationic cellulose polymer 
                 — 
                 — 
                 0.3 
                 0.5 
               
               
                 Polymer 6 
                 — 
                 1.5 
                 0.3 
                 0.2 
               
               
                 Chelant 2 
                 1.1 
                 2.0 
                 0.6 
                 1.5 
               
               
                 Optical Brightener 1 
                 0.20 
                 0.25 
                 0.01 
                 0.005 
               
               
                 Optical Brightener 3 
                 0.18 
                 0.09 
                 0.30 
                 0.005 
               
               
                 DTI 1 
                 0.1 
                 — 
                 0.2 
                 — 
               
               
                 DTI 2 
                 — 
                 0.1 
                 0.2 
                 — 
               
               
                 Glycerol 
                 5.3 
                 5.0 
                 5.0 
                 4.2 
               
               
                 Monoethanolamine 
                 10.0 
                 8.1 
                 8.4 
                 7.6 
               
               
                 Polyethylene glycol 
                 — 
                 — 
                 2.5 
                 3.0 
               
               
                 Potassium sulfite 
                 0.2 
                 0.3 
                 0.5 
                 0.7 
               
               
                 Protease 
                 0.80 
                 0.60 
                 0.40 
                 0.80 
               
               
                 Amylase 1 
                 0.20 
                 0.20 
                 0.200 
                 0.30 
               
               
                 Polishing enzyme 
                 — 
                 — 
                 0.005 
                 0.005 
               
               
                 Nuclease 
                 0.05 
                 0.010 
                 0.005 
                 0.005 
               
               
                 Dispersin B 
                 — 
                 0.010 
                 0.010 
                 0.010 
               
               
                 MgCl 2   
                 0.2 
                 0.2 
                 0.1 
                 0.3 
               
               
                 Structurant 
                 0.2 
                 0.1 
                 0.2 
                 0.2 
               
               
                 Acid Violet 50 
                 0.04 
                 0.03 
                 0.05 
                 0.03 
               
               
                 Perfume 
                 0.10 
                 0.30 
                 0.01 
                 0.05 
               
            
           
           
               
               
            
               
                 Solvents and misc. 
                 To 100% 
               
               
                 pH 
                 7.0-8.2 
               
               
                   
               
            
           
           
               
               
               
            
               
                 Finishing compositions 
                 17 
                 18 
               
               
                   
               
            
           
           
               
               
               
               
               
               
               
            
               
                 Compartment 
                 A 
                 B 
                 C 
                 A 
                 B 
                 C 
               
               
                   
               
               
                 Volume of each compartment 
                 40 ml 
                 5 ml 
                 5 ml 
                 40 ml 
                 5 ml 
                 5 ml 
               
               
                   
               
            
           
           
               
               
            
               
                 Ingredients 
                 Active material in Wt. % 
               
               
                   
               
            
           
           
               
               
               
               
               
               
               
            
               
                 Perfume 
                 1.6 
                 1.6 
                 1.6 
                 1.6 
                 1.6 
                 1.6 
               
               
                 Malodour reduction 
                 0.1 
                 0.01 
                 0.005 
                 0.3 
                 0.6 
                 0.9 
               
               
                 material(s) 
               
               
                 Violet DD 
                 0 
                 0.006 
                 0 
                 0 
                 0.004 
                 — 
               
               
                 TiO2 
                 — 
                 — 
                 0.1 
                 — 
                   
                 0.1 
               
               
                 Sodium Sulfite 
                 0.4 
                 0.4 
                 0.4 
                 0.3 
                 0.3 
                 0.3 
               
               
                 Polymer 5 
                 — 
                   
                   
                 2 
                 — 
                 — 
               
               
                 Hydrogenated castor oil 
                 0.14 
                 0.14 
                 0.14 
                 0.14 
                 0.14 
                 0.14 
               
            
           
           
               
               
            
               
                 Base Composition 13, 14, 
                 Add to 100% 
               
               
                 15 or 16 
               
               
                   
               
               
                 Based on total cleaning and/or treatment composition weight, enzyme levels are reported as raw material. 
               
            
           
         
       
     
     Example 7—Granular Laundry Detergent Compositions for Hand Washing or Washing Machines, Typically Top-Loading Washing Machines 
       
     
       
         
           
               
               
               
               
               
               
               
            
               
                   
                   
               
               
                   
                 19 
                 20 
                 21 
                 22 
                 23 
                 24 
               
            
           
           
               
               
            
               
                 Ingredient 
                 % weight 
               
               
                   
               
            
           
           
               
               
               
               
               
               
               
            
               
                 LAS 
                 11.33 
                 10.81 
                 7.04 
                 4.20 
                 3.92 
                 2.29 
               
               
                 Quaternary ammonium 
                 0.70 
                 0.20 
                 1.00 
                 0.60 
                 — 
                 — 
               
               
                 AE3S 
                 0.51 
                 0.49 
                 0.32 
                 — 
                 0.08 
                 0.10 
               
               
                 AE7 
                 8.36 
                 11.50 
                 12.54 
                 11.20 
                 16.00 
                 21.51 
               
               
                 Sodium Tripolyphosphate 
                 5.0 
                 — 
                 4.0 
                 9.0 
                 2.0 
                 — 
               
               
                 Zeolite A 
                 — 
                 1.0 
                 — 
                 1.0 
                 4.0 
                 1.0 
               
               
                 Sodium silicate 1.6R 
                 7.0 
                 5.0 
                 2.0 
                 3.0 
                 3.0 
                 5.0 
               
               
                 Sodium carbonate 
                 20.0 
                 17.0 
                 23.0 
                 14.0 
                 14.0 
                 16.0 
               
               
                 Polyacrylate MW 4500 
                 1.0 
                 0.6 
                 1.0 
                 1.0 
                 1.5 
                 1.0 
               
               
                 Polymer 6 
                 0.1 
                 0.2 
                 — 
                 — 
                 0.1 
                 — 
               
               
                 Carboxymethyl cellulose 
                 1.0 
                 0.3 
                 1.0 
                 1.0 
                 1.0 
                 1.0 
               
               
                 Acid Violet 50 
                 0.05 
                 — 
                 0.02 
                 — 
                 0.04 
                 — 
               
               
                 Violet DD 
                 — 
                 0.03 
                 — 
                 0.03 
                 — 
                 0.03 
               
               
                 Protease 2 
                 0.10 
                 0.10 
                 0.10 
                 0.10 
                 — 
                 0.10 
               
               
                 Amylase 
                 0.03 
                 — 
                 0.03 
                 0.03 
                 0.03 
                 0.03 
               
               
                 Lipase 
                 0.03 
                 0.07 
                 0.30 
                 0.10 
                 0.07 
                 0.40 
               
               
                 Polishing enzyme 
                 0.002 
                 — 
                 0.05 
                 — 
                 0.02 
                 — 
               
               
                 Nuclease 
                 0.001 
                 0.001 
                 0.01 
                 0.05 
                 0.002 
                 0.02 
               
               
                 Dispersin B 
                 0.001 
                 0.001 
                 0.05 
                 — 
                 0.001 
                 — 
               
               
                 Optical Brightener 1 
                 0.200 
                 0.001 
                 0.300 
                 0.650 
                 0.050 
                 0.001 
               
               
                 Optical Brightener 2 
                 0.060 
                 — 
                 0.650 
                 0.180 
                 0.200 
                 0.060 
               
               
                 Optical Brightener 3 
                 0.100 
                 0.060 
                 0.050 
                 — 
                 0.030 
                 0.300 
               
               
                 Chelant 1 
                 0.60 
                 0.80 
                 0.60 
                 0.25 
                 0.60 
                 0.60 
               
               
                 DTI 1 
                 0.32 
                 0.15 
                 0.15 
                 — 
                 0.10 
                 0.10 
               
               
                 DTI 2 
                 0.32 
                 0.15 
                 0.30 
                 0.30 
                 0.10 
                 0.20 
               
               
                 Sodium Percarbonate 
                 — 
                 5.2 
                 0.1 
                 — 
                 — 
                 — 
               
               
                 Sodium Perborate 
                 4.4 
                 — 
                 3.85 
                 2.09 
                 0.78 
                 3.63 
               
               
                 Nonanoyloxybenzensulfonate 
                 1.9 
                 0.0 
                 1.66 
                 0.0 
                 0.33 
                 0.75 
               
               
                 Tetraacetylehtylenediamine 
                 0.58 
                 1.2 
                 0.51 
                 0.0 
                 0.015 
                 0.28 
               
               
                 Photobleach 
                 0.0030 
                 0.0 
                 0.0012 
                 0.0030 
                 0.0021 
                 — 
               
               
                 S-ACMC 
                 0.1 
                 0.0 
                 0.0 
                 0.0 
                 0.06 
                 0.0 
               
               
                 Malodour reduction material(s) 
                 0.09 
                 0.01 
                 0.66 
                 0.06 
                 0.1 
                 0.005 
               
            
           
           
               
               
            
               
                 Sulfate/Moisture 
                 Balance 
               
               
                   
               
            
           
         
       
     
     Example 8—Granular Laundry Detergent Compositions Typically for Front-Loading Automatic Washing Machines 
       
     
       
         
           
               
               
               
               
               
               
               
            
               
                   
                   
               
               
                   
                 25 
                 26 
                 27 
                 28 
                 29 
                 30 
               
            
           
           
               
               
            
               
                 Ingredient 
                 % weight 
               
               
                   
               
            
           
           
               
               
               
               
               
               
               
            
               
                 LAS 
                 6.08 
                 5.05 
                 4.27 
                 3.24 
                 2.30 
                 1.09 
               
               
                 AE3S 
                 — 
                 0.90 
                 0.21 
                 0.18 
                 — 
                 0.06 
               
               
                 AS 
                 0.34 
                 — 
                 — 
                 — 
                 — 
                 — 
               
               
                 AE7 
                 4.28 
                 5.95 
                 6.72 
                 7.98 
                 9.20 
                 10.35 
               
               
                 Quaternary ammonium 
                 0.5 
                 — 
                 — 
                 0.3 
                 — 
                 — 
               
               
                 Crystalline layered silicate 
                 4.1 
                 — 
                 4.8 
                 — 
                 — 
                 — 
               
               
                 Zeolite A 
                 5.0 
                 — 
                 2.0 
                 — 
                 2.0 
                 2.0 
               
               
                 Citric acid 
                 3.0 
                 4.0 
                 3.0 
                 4.0 
                 2.5 
                 3.0 
               
               
                 Sodium carbonate 
                 11.0 
                 17.0 
                 12.0 
                 15.0 
                 18.0 
                 18.0 
               
               
                 Sodium silicate 2R 
                 0.08 
                 — 
                 0.11 
                 — 
                 — 
                 — 
               
               
                 Optical Brightener 1 
                 — 
                 0.25 
                 0.05 
                 0.01 
                 0.10 
                 0.02 
               
               
                 Optical Brightener 2 
                 — 
                 — 
                 0.25 
                 0.20 
                 0.01 
                 0.08 
               
               
                 Optical Brightener 3 
                 — 
                 0.06 
                 0.04 
                 0.15 
                 — 
                 0.05 
               
               
                 DTI 1 
                 0.08 
                 — 
                 0.04 
                 — 
                 0.10 
                 0.01 
               
               
                 DTI 2 
                 0.08 
                 — 
                 0.04 
                 0.10 
                 0.10 
                 0.02 
               
               
                 Soil release agent 
                 0.75 
                 0.72 
                 0.71 
                 0.72 
                 — 
                 — 
               
               
                 Acrylic/maleic acid copolymer 
                 1.1 
                 3.7 
                 1.0 
                 3.7 
                 2.6 
                 3.8 
               
               
                 Carboxymethyl cellulose 
                 0.2 
                 1.4 
                 0.2 
                 1.4 
                 1.0 
                 0.5 
               
               
                 Protease 3 
                 0.20 
                 0.20 
                 0.30 
                 0.15 
                 0.12 
                 0.13 
               
               
                 Amylase 3 
                 0.20 
                 0.15 
                 0.20 
                 0.30 
                 0.15 
                 0.15 
               
               
                 Lipase 
                 0.05 
                 0.15 
                 0.10 
                 — 
                 — 
                 — 
               
               
                 Amylase 2 
                 0.03 
                 0.07 
                 — 
                 — 
                 0.05 
                 0.05 
               
               
                 Cellulase 2 
                 — 
                 — 
                 — 
                 — 
                 0.10 
                 0.10 
               
               
                 Polishing enzyme 
                 0.003 
                 0.005 
                 0.020 
                 — 
                 — 
                 — 
               
               
                 Nuclease 
                 0.002 
                 0.010 
                 0.020 
                 0.020 
                 0.010 
                 0.003 
               
               
                 Dispersin B 
                 0.002 
                 0.010 
                 0.020 
                 0.020 
                 0.010 
                 0.002 
               
               
                 Tetraacetylehtylenediamine 
                 3.6 
                 4.0 
                 3.6 
                 4.0 
                 2.2 
                 1.4 
               
               
                 Sodium percabonate 
                 13.0 
                 13.2 
                 13.0 
                 13.2 
                 16.0 
                 14.0 
               
               
                 Chelant 3 
                 — 
                 0.2 
                 — 
                 0.2 
                 — 
                 0.2 
               
               
                 Chelant 2 
                 0.2 
                 — 
                 0.2 
                 — 
                 0.2 
                 0.2 
               
               
                 MgSO 4   
                 — 
                 0.42 
                 — 
                 0.42 
                 — 
                 0.4 
               
               
                 Perfume 
                 0.5 
                 0.6 
                 0.5 
                 0.6 
                 0.6 
                 0.6 
               
               
                 Malodour reduction material(s) 
                 0.05 
                 0.1 
                 0.005 
                 0.2 
                 0.02 
                 0.1 
               
               
                 Suds suppressor agglomerate 
                 0.05 
                 0.10 
                 0.05 
                 0.10 
                 0.06 
                 0.05 
               
               
                 Soap 
                 0.45 
                 0.45 
                 0.45 
                 0.45 
                 — 
                 — 
               
               
                 Acid Violet 50 
                 0.04 
                 — 
                 0.05 
                 — 
                 0.04 
                 — 
               
               
                 Violet DD 
                 — 
                 0.04 
                 — 
                 0.05 
                 — 
                 0.04 
               
               
                 S-ACMC 
                 0.01 
                 0.01 
                 — 
                 0.01 
                 — 
                 — 
               
               
                 Direct Violet 9 (active) 
                 — 
                 — 
                 0.0001 
                 0.0001 
                 — 
                 — 
               
            
           
           
               
               
            
               
                 Sulfate/Water &amp; Miscellaneous 
                 Balance 
               
               
                   
               
            
           
         
       
         
         AE1.8S is C 12-15  alkyl ethoxy (1.8) sulfate 
         AE3S is C 12-15  alkyl ethoxy (3) sulfate 
         AE7 is C 12-13  alcohol ethoxylate, with an average degree of ethoxylation of 7 
         AE8 is C 12-13  alcohol ethoxylate, with an average degree of ethoxylation of 8 
         AE9 is C 12-13  alcohol ethoxylate, with an average degree of ethoxylation of 9 
         Amylase 1 is Stainzyme®, 15 mg active/g 
         Amylase 2 is Natalase®, 29 mg active/g 
         Amylase 3 is Stainzyme Plus®, 20 mg active/g, 
         AS is C 12-14  alkylsulfate 
         Cellulase 2 is Celluclean™, 15.6 mg active/g 
         Xyloglucanase is Whitezyme®, 20 mg active/g 
         Chelant 1 is diethylene triamine pentaacetic acid 
         Chelant 2 is 1-hydroxyethane 1,1-diphosphonic acid 
         Chelant 3 is sodium salt of ethylenediamine-N,N′-disuccinic acid, (S,S) isomer (EDDS) 
         Dispersin B is a glycoside hydrolase, reported as 1000 mg active/g 
         DTI 1 is poly(4-vinylpyridine-1-oxide) (such as Chromabond S-403E®), 
         DTI 2 is poly(1-vinylpyrrolidone-co-1-vinylimidazole) (such as Sokalan HP56®). 
         HSAS is mid-branched alkyl sulfate as disclosed in U.S. Pat. No. 6,020,303 and U.S. Pat. No. 6,060,443 
         LAS is linear alkylbenzenesulfonate having an average aliphatic carbon chain length C 9 -C 15  (HLAS is acid form). 
         Lipase is Lipex®, 18 mg active/g 
         Malodour reduction is as described in the present disclosure material 
         Mannanase is Mannaway®, 25 mg active/g 
         Nuclease is a Phosphodiesterase SEQ ID NO 1, reported as 1000 mg active/g 
         Optical Brightener 1 is disodium 4,4′-bis{[4-anilino-6-morpholino- s -triazin-2-yl]-amino}-2,2′-stilbenedisulfonate 
         Optical Brightener 2 is disodium 4,4′-bis-(2-sulfostyryl)biphenyl (sodium salt) 
         Optical Brightener 3 is Optiblanc SPL10® from 3V Sigma 
         Perfume encapsulate is a core-shell melamine formaldahyde perfume microcapsule. 
         Photobleach is a sulfonated zinc phthalocyanine 
         Polishing enzyme is Para-nitrobenzyl esterase, reported as 1000 mg active/g 
         Polymer 1 is bis((C 2 H 5 O)(C 2 H 4 O)n)(CH 3 )—N + —C x H 2x —N + —(CH 3 )-bis((C 2 H 5 O)(C 2 H 4 O)n), wherein n=20-30, x=3 to 8 or sulfated or sulfonated variants thereof 
         Polymer 2 is ethoxylated (EO 15 ) tetraethylene pentamine 
         Polymer 3 is ethoxylated polyethylenimine 
         Polymer 4 is ethoxylated hexamethylene diamine 
         Polymer 5 is Acusol 305, provided by Rohm &amp; Haas 
         Polymer 6 is a polyethylene glycol polymer grafted with vinyl acetate side chains, provided by BASF. 
         Protease is Purafect Prime®, 40.6 mg active/g 
         Protease 2 is Savinase®, 32.89 mg active/g 
         Protease 3 is Purafect®, 84 mg active/g 
         Quaternary ammonium is C 12-14  Dimethylhydroxyethyl ammonium chloride 
         S-ACMC is Reactive Blue 19 Azo-CM-Cellulose provided by Megazyme 
         Soil release agent is Repel-o-tex® SF2 
         Structurant is Hydrogenated Castor Oil 
         Violet DD is a thiophene azo dye provided by Milliken 
       
    
     The dimensions and values disclosed herein are not to be understood as being strictly limited to the exact numerical values recited. Instead, unless otherwise specified, each such dimension is intended to mean both the recited value and a functionally equivalent range surrounding that value. For example, a dimension disclosed as “40 mm” is intended to mean “about 40 mm.” 
     Every document cited herein, including any cross referenced or related patent or application and any patent application or patent to which this application claims priority or benefit thereof, is hereby incorporated herein by reference in its entirety unless expressly excluded or otherwise limited. The citation of any document is not an admission that it is prior art with respect to any invention disclosed or claimed herein or that it alone, or in any combination with any other reference or references, teaches, suggests or discloses any such invention. Further, to the extent that any meaning or definition of a term in this document conflicts with any meaning or definition of the same term in a document incorporated by reference, the meaning or definition assigned to that term in this document shall govern. 
     While particular embodiments of the present invention have been illustrated and described, it would be obvious to those skilled in the art that various other changes and modifications can be made without departing from the spirit and scope of the invention. It is therefore intended to cover in the appended claims all such changes and modifications that are within the scope of this invention.