Patent Publication Number: US-2022218357-A1

Title: Delivery systems for implants

Description:
CROSS-REFERENCE TO RELATED APPLICATIONS 
     This application is a continuation-in-part of PCT Application No. PCT/EP2021/050451, filed on Jan. 12, 2021, the contents of which as are hereby incorporated by reference in their entirety. 
    
    
     TECHNICAL FIELD 
     The present disclosure relates to delivery systems for implants. More particularly, the present disclosure relates to a delivery system for gripping and releasing an implant, and an embolization system actuatable to release an embolization device and having a flexible joint. 
     BACKGROUND 
     When delivering medical implants to a location within a bodily lumen of a patient, the delivery system must often navigate tortuous anatomies, including sharp turns in the vasculature, for example at branches. Such tortuous anatomies cause strain to be experienced the delivery system caused by the bending forces exerted on the system as it navigates the anatomy. If the strain is transmitted to the medical implant or to the detach mechanism connecting the medical implant to the delivery system, this can cause premature detachment of the medical implant or even damage to the medical implant. 
     Furthermore, the delivery mechanism may comprise a detach mechanism which is actuatable to release the medical implant. The detach mechanism risks premature actuation, especially when strain is imparted onto the delivery system by bending forces experienced in the bodily lumen. 
     There is therefore a need for reducing the potential damage to medical implant delivery systems and medical implants during delivery in complex anatomies, and further a need for improving the reliability of detach mechanisms so that they are less likely to break or detach from the medical implant prematurely. 
     SUMMARY 
     According to a first aspect of the present disclosure, there is provided a delivery system for delivering and deploying an implant to a bodily lumen, comprising: a delivery element configured to extend through a lumen of a delivery catheter; a detach mechanism connected to a distal portion of the delivery element, the detach mechanism having a first configuration in which the detach mechanism is configured to grip the implant and a second configuration in which the detach mechanism is configured to release the implant; and an actuating mechanism configured to extend through the lumen of the delivery catheter to the detach mechanism, the actuating mechanism movable between a first position and a second position, wherein moving the actuating mechanism from the first position to the second position changes the detach mechanism from the first configuration to the second configuration. 
     According to a second aspect of the present disclosure, there is provided an embolization system, comprising: an embolization device, comprising a self-expandable skeleton and a flow restricting layer mounted on the skeleton, the embolization device having a collapsed delivery configuration in which the embolization device is configured to fit inside a delivery catheter, and an expanded deployed configuration in which the skeleton is configured to anchor the embolization device to a bodily lumen; wherein in the expanded deployed configuration the flow restricting layer extends across the bodily lumen to restrict blood flow through the bodily lumen; a detach mechanism for connecting the embolization device to a delivery element and actuatable to release the embolization device from the delivery element; and a flexible joint having a higher flexibility than the embolization device, the flexible joint for allowing the embolization device to tilt with respect to the delivery element when the delivery element is connected to the embolization device. 
    
    
     
       BRIEF DESCRIPTION OF THE DRAWINGS 
       To enable better understanding of the present disclosure, and to show how the same may be carried into effect, reference will now be made, by way of example only, to the accompanying schematic drawings, in which: 
         FIG. 1  shows a schematic view of an embolization system according to one or more embodiments shown and described herein; 
         FIG. 2A  shows a schematic view of an embolization system in a bodily lumen according to one or more embodiments shown and described herein; 
         FIG. 2B  shows the embolization system of  FIG. 2A  in another configuration; 
         FIG. 2C  shows the embolization system of  FIG. 2A  in another configuration; 
         FIG. 3A  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 3B  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 3C  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 3D  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 4A  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 4B  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 4C  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 4D  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 5A  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 5B  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 5C  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 5D  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 6A  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 6B  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 6C  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 6D  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 7A  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 7B  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 7C  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 7D  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 8A  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 8B  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 8C  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 8D  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 9A  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 9B  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 9C  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 9D  shows a schematic view of another embolization system according to one or more embodiments shown and described herein; 
         FIG. 10A  shows a schematic view of a delivery system according to one or more embodiments shown and described herein; 
         FIG. 10B  shows the delivery system of  FIG. 10A  in a second configuration; 
         FIG. 11A  shows a schematic view of a delivery system in a bodily lumen according to one or more embodiments shown and described herein; 
         FIG. 11B  shows the delivery system of  FIG. 10A  in a second configuration; 
         FIG. 11C  shows the delivery system of  FIG. 10A  in a third configuration; 
         FIG. 12A  shows a schematic view of a delivery system according to one or more embodiments shown and described herein; 
         FIG. 12B  shows the delivery system of  FIG. 12A  in a second configuration; 
         FIG. 13A  shows a schematic view of a delivery system according to one or more embodiments shown and described herein; 
         FIG. 13B  shows the delivery system of  FIG. 13A  in a second configuration; 
         FIG. 14A  shows a schematic view of a delivery system according to one or more embodiments shown and described herein; 
         FIG. 14B  shows the delivery system of  FIG. 14A  in a second configuration; 
         FIG. 15A  shows a schematic view of a delivery system according to one or more embodiments shown and described herein; 
         FIG. 15B  shows the delivery system of  FIG. 15A  in a second configuration; 
         FIG. 16A  shows a schematic view of a delivery system according to one or more embodiments shown and described herein; 
         FIG. 16B  shows the delivery system of  FIG. 16A  in a second configuration; 
         FIG. 17A  shows a schematic view of a delivery system according to one or more embodiments shown and described herein; 
         FIG. 17B  shows the delivery system of  FIG. 17A  in a second configuration; 
         FIG. 18  shows a schematic view of an embolization device according to one or more embodiments shown and described herein; 
         FIG. 19A  shows a schematic view of an embolization system according to one or more embodiments shown and described herein; 
         FIG. 19B  shows a schematic view of an embolization system according to one or more embodiments shown and described herein; 
         FIG. 20A  shows a schematic diagram of a breakable detachment element for an embolization system according to one or more embodiments shown and described herein; 
         FIG. 20B  shows a schematic diagram of another breakable detachment element for an embolization system according to one or more embodiments shown and described herein; and 
         FIG. 20C  shows a schematic diagram of another breakable detachment element for an embolization system according to one or more embodiments shown and described herein. 
     
    
    
     DETAILED DESCRIPTION 
     As disclosed herein, the term “skeleton” may be understood to mean a structure which is configured to provide structural support to a layer of material formed on the skeleton. The skeleton may comprise a plurality of struts providing the structural support. 
     As disclosed herein, the term “flow-restricting layer” may be understood as a component part of an embolization device which is configured to extend across a substantial cross-section of the embolization device when deployed in a bodily lumen such that blood-flow through the lumen is at least partially restricted by the component. 
     As disclosed herein, the term “delivery element” may be understood as any element configured to fit inside a delivery catheter which is able to push a medical implant through the delivery catheter to a distal end of the delivery catheter. 
     As disclosed herein, the term “breakable detachment element” may be understood as an element configured to break upon application of a predetermined force. More specifically, it may refer to any element which is configured to break irreversibly such that two elements which are connected by the detachment element are separated irreversibly. The breakable detachment element may connect two elements of a system such that when a force (for example a shear force or twisting force) is applied to the system, the breakable detachment element preferentially breaks before the other elements of the system. 
       FIG. 1  shows an embolization system  100  comprising an embolization device  110  and a detach mechanism  140  for connecting the embolization device  110  to a delivery element  150  (which may be, for example, a wire, ribbon or similar configured to extend through a delivery catheter). The embolization system  100  may further comprise a flexible joint  130  having a higher flexibility than the embolization device  110 , configured to allow the embolization device  110  to tilt with respect to the delivery element  150 . The embolization device  110  may be considered a “Micro Vascular Plug System” (MVP) suitable for peripheral embolization, such as the MVP manufactured by Medtronic. 
     Whilst the flexible joint  130  is shown in  FIG. 1  as being distal of the detach mechanism  140 , in other embodiments the detach mechanism  140  may be distal of the flexible joint  130 . 
     The embolization device  110  may further comprise a self-expandable skeleton  112  (which may comprise, for example, a plurality of interconnected or braided struts forming a self-expanding cage). The embolization device  110  may further comprise a flow-restricting layer  114  mounted onto the skeleton  112 . The embolization device  110  has a collapsed delivery configuration in which the embolization device  110  is configured to fit inside a delivery catheter, and an expanded deployed configuration in which the skeleton  112  is configured to anchor the embolization device  110  to a bodily lumen. The flow restricting layer  114 , being mounted to the skeleton  112 , is moved between the collapsed delivery configuration and the expanded deployed configuration by the self-expandable skeleton  112 . In the expanded deployed configuration, the flow restricting layer  114  extends at least partially and across the bodily lumen to restrict blood flow through the bodily lumen. In some embodiments, the flow restricting layer  114  is configured to extend wholly across the bodily lumen in the expanded deployed configuration. 
     The self-expandable skeleton  112  may comprise an anchoring portion which is configured to contact the bodily lumen in the expanded deployed configuration and provide the anchoring force of the embolization device  110 . The anchoring portion may be, for example, a cylindrical shape in the expanded deployed configuration. The self-expandable skeleton  112  may also comprise one or more of a proximal tapered portion  120  and a distal tapered portion  116 . The distal tapered portion  116  may terminate at a tip  118 . The tip  118  may be an atraumatic shape, such as a rounded shape, and/or may be formed of a material which is softer than the material of the skeleton  112 , to reduce the risk of perforation of vessel walls as the embolization device  110  is deployed. The proximal tapered portion  120  improves retrievability of the embolization device  110  by allowing it to be re-collapsed by a delivery catheter. The proximal tapered portion  120  may terminate at a proximal fixing element  122  which connects the proximal end of the skeleton  112  to the flexible joint  130  or the detach mechanism  140 . Alternatively, the proximal end of the skeleton  112  may be directly connected to the flexible joint  130  or detach mechanism  140 . In some embodiments, instead of one or both of the tapered portions the embolization device  110  comprises a portion that extends radially inwards of the anchoring portion (i.e. does not have longitudinal extent) to connect the anchoring portion to the proximal fixing element  122 , flexible joint  130  or detach mechanism  140 . The self-expandable skeleton  112  may be made of any self-expandable material, for example, stainless steel or nitinol. 
     The embolization device  110  may comprise one or more radiopaque markers to assist locating the embolization device  110  when deployed inside the bodily lumen. For example, the proximal fixing element  122  and/or the distal tip  118  and/or the skeleton  112  may be made of a radiopaque material. 
     The detach mechanism  140  is configured to connect the embolization device  110  to the delivery element  150  and is actuatable to release the embolization device  110  from the delivery element  150 . The detach mechanism  140  may be a reversible detach mechanism such as a screw thread (i.e. the detachment may be reversable), or the detach mechanism  140  may be an irreversible detach mechanism such as an electrolytic element, as disclosed in further detail herein. Any of the embolization systems disclosed herein may comprise any such detach mechanism. 
     The flexible joint  130  may be provided as part of the embolization device  110  or may be provided as part of the delivery element  150 . 
     The flow restricting layer  114  is illustrated as covering the skeleton  112  from a distal end of the embolization device  110  to a point along the anchoring portion of the skeleton  112 . In other embodiments, the flow restricting layer  114  may extend from the proximal end of the embolization device to a point along the anchoring portion of the skeleton  112 , or may cover the entire length of skeleton  112 . The flow restricting layer  114  may comprise at least one longitudinal end which is closed such that in the expanded deployed configuration, the flow restricting layer  114  extends across the entire diameter of the bodily lumen. The flow restricting layer  114  may be any suitable flexible layer which is able to move between the collapsed delivery configuration and the expanded deployed configuration, and may for example be a flexible polymer, and more specifically PTFE or polyurethane, polyethylene or a composite thereof. The layer  114  may be separately formed and mounted to the skeleton  112  by welding, adhesive, tying or any other suitable means for mounting to the skeleton  112 , on the inner side or the outer side of the skeleton  112 . Alternatively, the layer  114  may be formed on the skeleton by dip-casting. 
       FIG. 2A  shows an embolization system  100  (for example the embolization system  100  described with respect to  FIG. 1 ) in a collapsed delivery configuration inside a delivery catheter  200 . In use, the delivery catheter  200  is advanced through the vasculature of a patient to a target site. The embolization device  110  is then collapsed into the collapsed delivery configuration and advanced through to the distal tip of the delivery catheter  200  by delivery element  150 . 
       FIG. 2B  shows the embolization system  100  in a partially deployed configuration in which the embolization device  110  has been deployed from the distal tip of the delivery catheter  200  and has expanded to the expanded deployed configuration in which the embolization device  110  is anchored to the vessel wall  250  of the bodily lumen at the target site. As in the illustrated embodiment, in some cases the deployment site of the embolization device  110  is tilted at a large angle compared to the delivery element  150 . Such a large tilt angle can exert large bending forces on the embolization device  110  and may cause damage to the embolization device  110  or cause it to detach from delivery element  150  prematurely. In the illustrated embodiment, as the embolization system  100  is provided with flexible joint  130  which has a higher flexibility than embolization device  110 , the bending is taken up primarily by the flexible joint  130 , reducing or avoiding any bending forces being transmitted to the embolization device  110  and thereby avoiding damage to the embolization device  110  upon deployment at a substantial tilt angle, or premature detachment of the embolization device  110 . 
     Once it is determined that the embolization device  110  is correctly located in the bodily lumen, the detach mechanism  140  can be actuated by the user to detach the embolization device  110  from the delivery element  150 , as shown in  FIG. 2C . The delivery element  150  and the delivery catheter  200  are retracted in a proximal direction P and removed from the bodily lumen, and the embolization device  110  is anchored to the bodily lumen in the desired location. 
       FIG. 3A  shows an embodiment of the embolization system  100  described with respect to  FIG. 1 . In the embodiment of  FIG. 3A , the flexible joint  130  is provided distally to the detach mechanism  140 . In the illustrated embodiment, the flexible joint  130  may comprise an articulating joint, which comprises interlocking loops  300   a  and  300   b . Loop  300   b  is connected to the embolization device  110  and loop  300   a  is connected to the detach mechanism  140 . The interlocking loops  300   a ,  300   b  may be made of any suitable material such as a polymer or metal. Detach mechanism  140  may include a female screw thread  140   b  which is configured to connect to a male screw thread  140   a  on a delivery element  150  (in other embodiments the detach mechanism  140  comprises a male screw thread connected to the flexible joint  130 , configured to connect to a female screw thread on the delivery element  150 ). The loop  300   b  may be formed on the proximal fixing element  122  or may be formed directly on the skeleton  114  of embolization device  110 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 3A . The interlocking loops  300   a  and  300   b  allow the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, the delivery element  150  may be rotated to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 3B  shows another embodiment of the embolization system  100  described with respect to  FIG. 1 . In the embodiment of  FIG. 3B , the flexible joint  130  is provided proximally to the detach mechanism  140 . In the depicted embodiment, the flexible joint  130  may comprise an articulating joint, which comprises interlocking loops  300   a  and  300   b . The interlocking loops  300   a ,  300   b  may be made of any suitable material such as a polymer or metal. Loop  300   b , in the present embodiment, is connected to the detach mechanism  140  and loop  300   a  is connected to the delivery element  150 . Detach mechanism  140  may include a female screw thread  140   b  connected to embolization device  110  which is configured to connect to a male screw thread  140   a  connected to loop  300   b  (in other embodiments the detach mechanism  140  comprises a male screw thread connected to the embolization device  110 , configured to connect to a female screw thread connected to the loop  300   b ). the female screw thread  140   b  may be formed on the proximal fixing element  122  or may be formed directly on the skeleton  114  of embolization device  110 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 3B . The interlocking loops  300   a  and  300   b  allow the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, the delivery element  150  may be rotated to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 3C  shows another embodiment of the embolization system described with respect to  FIG. 1 . In the embodiment of  FIG. 3C , the flexible joint  130  is provided distally to the detach mechanism  140 . The flexible joint  130  may comprise an articulating joint, which comprises interlocking loops  300   a  and  300   b . The interlocking loops  300   a ,  300   b  may be made of any suitable material such as a polymer or metal. Loop  300   b  is connected to the embolization device  110  and loop  300   a  is connected to the detach mechanism  140 . The loop  300   b  may be formed on the proximal fixing element  122  or may be formed directly on the skeleton  114  of embolization device  110 . Detach mechanism  140  may comprise an electrolytic element  145  connecting the flexible joint  130  and the delivery element  150 . The electrolytic element  145  is electrically connected to a proximal end of the embolization system  100 , and is operable to disintegrate by electrolysis in the body lumen to detach the embolization device  110  from the delivery element  150 . By applying an electric current to the electrolytic element, at a current amplitude, a voltage and for a duration of time, such that the electrical energy supplied to the electrolytic element is above a disintegration energy of the electrolytic element, the delivery element  150  is detached from the embolization device  110 . The delivery element  150  may be electrically conductive itself or a conductive wire (not shown) may be provided that runs along the length of the delivery element  150 . The electrolytic element  145  may be formed of any material configured to disintegrate by electrolysis in the body lumen upon application of an electric current. Suitable materials include platinum, stainless steel, nitinol and cobalt chromium. The electric current applied may be a positive direct current. A corresponding electrode may be provided proximal to the location of the embolization device  110  to complete the circuit, for example inside the bodily lumen adjacent the electrolytic element or on the surface of the patient proximal to the location of the embolization device  110 . It is noted that in some embodiments, loop  300   a  or  300   b  may be formed of the electrolytic material  145 , thus acting as both the flexible joint  130  and the detach mechanism  140 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 3C . The interlocking loops  300   a  and  300   b  allow the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, electric current is applied to the electrolytic element  145  to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 3D  shows another embodiment of the embolization system described with respect to  FIG. 1 . In the embodiment of  FIG. 3D , the flexible joint  130  is provided proximally to the detach mechanism  140 . The flexible joint  130  may comprise an articulating joint, which comprises interlocking loops  300   a  and  300   b . The interlocking loops  300   a ,  300   b  may be made of any suitable material such as a polymer or metal. Loop  300   b  is connected to the detach mechanism  140  and loop  300   a  is connected to the delivery element  150 . Detach mechanism  140  comprises an electrolytic element  145  connecting the flexible joint  130  and the embolization device  110 . Loop  300   b  may be formed on the electrolytic element  145  or one or more of loops  300   a ,  300   b  may themselves be made of electrolytic material such that it acts as both the joint  130  and the electrolytic element  145 . The electrolytic element  145  is electrically connected to a proximal end of the embolization system  100 , and is operable to disintegrate by electrolysis in the body lumen to detach the embolization device  110  from the delivery element  150 . By applying an electric current to the electrolytic element, at a current amplitude, a voltage and for a duration of time, such that the electrical energy supplied to the electrolytic element is above a disintegration energy of the electrolytic element, the delivery element  150  is detached from the embolization device  110 . The delivery element  150  may be electrically conductive itself or a conductive wire (not shown) may be provided that runs along the length of the delivery element  150 . The loops  300   a ,  300   b  may be electrically conductive themselves or a flexible conductive wire may extend across the joint  130  to electrically connect the electrolytic element  145 . The electrolytic element  145  may be formed of any material configured to disintegrate by electrolysis in the body lumen upon application of an electric current. Suitable materials include platinum, stainless steel, nitinol and cobalt chromium. The electric current applied may be a positive direct current. A corresponding electrode may be provided proximal to the location of the embolization device  110  to complete the circuit, for example inside the bodily lumen adjacent the electrolytic element or on the surface of the patient proximal to the location of the embolization device  110 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 3D . The interlocking loops  300   a  and  300   b  allow the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, electric current is applied to the electrolytic element  145  to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 4A  shows an embodiment of the embolization system  100  described with respect to  FIG. 1 . In the embodiment of  FIG. 4A , the flexible joint  130  is provided distally to the detach mechanism  140 . The flexible joint  130  may comprise an articulating joint, which comprises a hinge pin  302  and a hinge loop  304  connected to the hinge pin  302 . The hinge pin  302  and hinge loop  304  may be made of any suitable material such as a polymer or metal. Hinge loop  304  is connected to the embolization device  110  (e.g. formed on proximal fixing element  122  or directly on skeleton  114 ). Detach mechanism  140  may comprise a female screw thread  140   b  which is configured to connect to a male screw thread  140   a  on a delivery element  150  (in other embodiments the detach mechanism  140  comprises a male screw thread connected to the flexible joint  130 , configured to connect to a female screw thread on the delivery element  150 ). Hinge loop  304  may be formed on the proximal fixing element  122  or may be formed directly on the skeleton  114  of embolization device  110 . In some embodiments, the hinge pin  302  is formed on the proximal fixing element  122  or directly on the skeleton  114 , and the hinge loop  304  is connected to the detach mechanism  140 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 4A . The hinge pin  302  and hinge loop  304  allow the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, the delivery element  150  may be rotated to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 4B  shows an embodiment of the embolization system  100  described with respect to  FIG. 1 . In the embodiment of  FIG. 4B , the flexible joint  130  is provided proximally to the detach mechanism  140 . The flexible joint may comprise an articulating joint, which comprises a hinge pin  302  and a hinge loop  304  connected to the hinge pin  302 . The hinge pin  302  and hinge loop  304  may be made of any suitable material such as a polymer or metal. Hinge loop  304  is connected to detach mechanism  140  and hinge pin  302  is connected to the delivery element  150 . Detach mechanism  140  may comprise a female screw thread  140   b  formed on the proximal fixing element  122  or directly on the skeleton  114 , which is configured to connect to a male screw thread  140   a  connected to flexible joint  130  (in other embodiments the detach mechanism  140  comprises a male screw thread connected to the embolization device  110 , configured to connect to a female screw thread connected to the delivery element  150  via flexible joint  130 ). In some embodiments, the hinge pin  302  is connected to detach mechanism  140 , and the hinge loop  304  is connected to the delivery element  150 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 4B . The interlocking hinge pin  302  and hinge loop  304  allow the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, the delivery element  150  may be rotated to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 4C  shows an embodiment of the embolization system  100  described with respect to  FIG. 1 . In the embodiment of  FIG. 4C , the flexible joint  130  is provided distally to the detach mechanism  140 . The flexible joint  130  may comprise an articulating joint, which comprises a hinge pin  302  and a hinge loop  304  connected to the hinge pin  302  The hinge pin  302  and hinge loop  304  may be made of any suitable material such as a polymer or metal. Hinge loop  304  is connected to embolization device  110  (either via proximal fixing element  122  or directly to the skeleton  114 ). Hinge pin  302  is connected to detach mechanism  140 . In other embodiments hinge loop  304  is connected to detach mechanism  140  and hinge pin  302  is connected to embolization device  110 . Detach mechanism  140  may include an electrolytic element  145  connecting the flexible joint  130  and the delivery element  150 . The electrolytic element  145  is electrically connected to a proximal end of the embolization system  100 , and is operable to disintegrate by electrolysis in the body lumen to detach the embolization device  110  from the delivery element  150 . By applying an electric current to the electrolytic element, at a current amplitude, a voltage and for a duration of time, such that the electrical energy supplied to the electrolytic element is above a disintegration energy of the electrolytic element, the delivery element  150  is detached from the embolization device  110 . The delivery element  150  may be electrically conductive itself or a conductive wire (not shown) may be provided that runs along the length of the delivery element  150 . The electrolytic element  145  may be formed of any material configured to disintegrate by electrolysis in the body lumen upon application of an electric current. Suitable materials include platinum, stainless steel, nitinol and cobalt chromium. The electric current applied may be a positive direct current. A corresponding electrode may be provided proximal to the location of the embolization device  110  to complete the circuit, for example inside the bodily lumen adjacent the electrolytic element or on the surface of the patient proximal to the location of the embolization device  110 . It is noted that in some embodiments, the more proximal of the hinge pin  302  or hinge loop  304  may be formed of the electrolytic material  145 , the flexible joint  130  thus acting as both the flexible joint  130  and the detach mechanism  140 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 4C . The interlocking hinge pin  302  and hinge loop  304  allow the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, electric current is applied to the electrolytic element  145  to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 4D  shows another embodiment of the embolization system described with respect to  FIG. 1 . In the embodiment of  FIG. 4D , the flexible joint  130  is provided proximally to the detach mechanism  140 . The flexible joint  130  may comprise an articulating joint, which comprises a hinge pin  302  and a hinge loop  304  connected to the hinge pin  302 . The hinge pin  302  and hinge loop  304  may be made of any suitable material such as a polymer or metal. Hinge loop  304  is connected to detach mechanism  140  and hinge pin  302  is connected to delivery element  150 . In other embodiments, hinge loop  304  is connected to delivery element  150  and hinge pin  302  is connected to detach mechanism  140 . Detach mechanism  140  comprises an electrolytic element  145  connecting the flexible joint  130  and the embolization device  110 . The more distal of the hinge pin  302  and hinge loop  304  may be formed on the electrolytic element  145  or may itself be made of electrolytic material such that it acts as both the joint  130  and the electrolytic element  145 . The electrolytic element  145  is electrically connected to a proximal end of the embolization system  100 , and is operable to disintegrate by electrolysis in the body lumen to detach the embolization device  110  from the delivery element  150 . By applying an electric current to the electrolytic element, at a current amplitude, a voltage and for a duration of time, such that the electrical energy supplied to the electrolytic element is above a disintegration energy of the electrolytic element, the delivery element  150  is detached from the embolization device  110 . The delivery element  150  may be electrically conductive itself or a conductive wire (not shown) may be provided that runs along the length of the delivery element  150 . The hinge pin  302  and hinge loop  304  may be electrically conductive themselves or a flexible conductive wire may extend across the joint  130  to electrically connect the electrolytic element  145 . The electrolytic element  145  may be formed of any material configured to disintegrate by electrolysis in the body lumen upon application of an electric current. Suitable materials include platinum, stainless steel, nitinol and cobalt chromium. The electric current applied may be a positive direct current. A corresponding electrode may be provided proximal to the location of the embolization device  110  to complete the circuit, for example inside the bodily lumen adjacent the electrolytic element or on the surface of the patient proximal to the location of the embolization device  110 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 4D . The interlocking hinge pin  302  and hinge loop  304  allow the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, electric current is applied to the electrolytic element  145  to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 5A  shows an embodiment of the embolization system  100  described with respect to  FIG. 1 . In the embodiment of  FIG. 5A , the flexible joint  130  is provided distally to the detach mechanism  140 . The flexible joint  130  in the present embodiment comprises a resiliently deformable joint, and more particularly a spring  306  (although any suitable resiliently deformable element may be used such as an elastic material). The spring  306  may be made of any suitable material such as a polymer or metal. Optionally, the flexible joint  130  may additionally comprise inextensible wire or thread  308  (made of e.g. a polymer or metal) connecting the detach mechanism  140  and the embolization device  110 , which inhibits the spring  306  from being overstretched. The spring  306  is connected to the detach mechanism  140  at a proximal end and embolization device  110  via the proximal fixing element  122  or skeleton  112  at a distal end. Detach mechanism  140  may comprise a female screw thread  140   b  which is configured to connect to a male screw thread  140   a  on a delivery element  150  (in other embodiments the detach mechanism  140  comprises a male screw thread connected to the flexible joint  130 , configured to connect to a female screw thread on the delivery element  150 ). 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 5A . Spring  306  allows the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, the delivery element  150  may be rotated to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C  (whilst the flexible spring  306  allows the embolization device  110  to rotate axially relative to the delivery element  150 , with sufficient rotation of the delivery element  150  tension in the spring  306  becomes sufficient to allow the detach mechanism  140  to unscrew with further rotation). 
       FIG. 5B  shows an embodiment of the embolization system  100  described with respect to  FIG. 1 . In the embodiment of  FIG. 5B , the flexible joint is provided proximally to the detach mechanism  140 . The flexible joint may comprise a resiliently deformable joint, and more particularly a spring  306  (although any suitable resiliently deformable element may be used such as an elastic material). The spring  306  may be made of any suitable material such as a polymer or metal. Optionally, the flexible joint  130  may additionally comprise inextensible wire or thread  308  (made of e.g. a polymer or metal) connecting the detach mechanism  140  and the embolization device  110 , which inhibits the spring  306  from being overstretched. The spring  306  is connected to the detach mechanism at a distal end and the delivery element at a proximal end. Detach mechanism  140  may comprise a female screw thread  140   b  formed on the proximal fixing element  122  or directly on the skeleton  114 , which is configured to connect to a male screw thread  140   a  connected to flexible joint  130  (in other embodiments the detach mechanism  140  comprises a male screw thread connected to the embolization device  110 , configured to connect to a female screw thread connected to the delivery element  150  via flexible joint  130 ). 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 5B . The resiliently deformable element allows the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, the delivery element  150  may be rotated to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 5C  shows an embodiment of the embolization system  100  described with respect to  FIG. 1 . In the embodiment of  FIG. 5C , the flexible joint is provided distally to the detach mechanism. The flexible joint may comprise a resiliently deformable joint, and more particularly a spring  306  (although any suitable resiliently deformable element may be used such as an elastic material). The spring  306  may be made of any suitable material such as a polymer or metal. Optionally, the flexible joint  130  may additionally comprise inextensible wire or thread  308  (made of e.g. a polymer or metal) connecting the detach mechanism  140  and the embolization device  110 , which inhibits the spring  306  from being overstretched. The spring  306  is connected to the embolization device  110  at a distal end (e.g. via proximal fixing element  122  or skeleton  114 ) and the detach mechanism  140  at a proximal end. Detach mechanism  140  may comprise an electrolytic element  145  connecting the flexible joint  130  and the delivery element  150 . The electrolytic element  145  is electrically connected to a proximal end of the embolization system  100 , and is operable to disintegrate by electrolysis in the body lumen to detach the embolization device  110  from the delivery element  150 . By applying an electric current to the electrolytic element, at a current amplitude, a voltage and for a duration of time, such that the electrical energy supplied to the electrolytic element is above a disintegration energy of the electrolytic element, the delivery element  150  is detached from the embolization device  110 . The delivery element  150  may be electrically conductive itself or a conductive wire (not shown) may be provided that runs along the length of the delivery element  150 . The electrolytic element  145  may be formed of any material configured to disintegrate by electrolysis in the body lumen upon application of an electric current. Suitable materials include platinum, stainless steel, nitinol and cobalt chromium. The electric current applied may be a positive direct current. A corresponding electrode may be provided proximal to the location of the embolization device  110  to complete the circuit, for example inside the bodily lumen adjacent the electrolytic element or on the surface of the patient proximal to the location of the embolization device  110 . It is noted that in some embodiments, the spring  306  (and the wire or thread  308 ) may be made of the electrolytic material  145 , the flexible joint  130  thus acting as both the flexible joint  130  and the detach mechanism  140 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 5C . The resiliently deformable element allows the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, electric current is applied to the electrolytic element  145  to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 5D  shows another embodiment of the embolization system described with respect to  FIG. 1 . In the embodiment of  FIG. 5D , the flexible joint  130  is provided proximally to the detach mechanism  140 . The flexible joint  130  may comprise a resiliently deformable joint, and more particularly a spring  306  (although any suitable resiliently deformable element may be used such as an elastic material). The spring  306  may be made of any suitable material such as a polymer or metal. Optionally, the flexible joint  130  may additionally comprise inextensible wire or thread  308  (made of e.g. a polymer or metal) connecting the detach mechanism  140  and the embolization device  110 , which inhibits the spring  306  from being overstretched. The spring  306  is connected to the detach mechanism  140  at a distal end and the delivery element  150  at a proximal end. Detach mechanism  140  may comprise an electrolytic element  145  connecting the flexible joint  130  and the embolization device  110 . The spring  306  and wire or thread  308  (where present) may be formed on the electrolytic element  145  or may themselves be made of electrolytic material such that they act as both the joint  130  and the electrolytic element  145 . The electrolytic element  145  is electrically connected to a proximal end of the embolization system  100 , and is operable to disintegrate by electrolysis in the body lumen to detach the embolization device  110  from the delivery element  150 . By applying an electric current to the electrolytic element, at a current amplitude, a voltage and for a duration of time, such that the electrical energy supplied to the electrolytic element is above a disintegration energy of the electrolytic element, the delivery element  150  is detached from the embolization device  110 . The delivery element  150  may be electrically conductive itself or a conductive wire (not shown) may be provided that runs along the length of the delivery element  150 . The spring  306  and/or the thread  308  may be electrically conductive themselves or a flexible conductive wire may extend across the joint  130  to electrically connect the electrolytic element  145 . The electrolytic element  145  may be formed of any material configured to disintegrate by electrolysis in the body lumen upon application of an electric current. Suitable materials include platinum, stainless steel, nitinol and cobalt chromium. The electric current applied may be a positive direct current. A corresponding electrode may be provided proximal to the location of the embolization device  110  to complete the circuit, for example inside the bodily lumen adjacent the electrolytic element or on the surface of the patient proximal to the location of the embolization device  110 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 5D . The resiliently deformable element allows the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, electric current is applied to the electrolytic element  145  to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 6A  shows an embodiment of the embolization system  100  described with respect to  FIG. 1 . In the embodiment of  FIG. 6A , the flexible joint  130  is provided distally to the detach mechanism  140 . The flexible joint  130  may comprise a flexible material  310  (for example a wire, thread or ribbon). The flexible material  310  may be made of any suitable material such as a polymer or metal. The flexible material  310  is connected to the detach mechanism  140  at a proximal end and the embolization device  110  (proximal fixing element  122  or skeleton  112 ) at a distal end. The flexible material  310  may be crimped to the detach mechanism  140  and the embolization device by crimped hypotubes  312 . Alternatively, the elongate material  310  may be attached by adhesive or welding. Detach mechanism  140  comprises a female screw thread  140   b  which is configured to connect to a male screw thread  140   a  on a delivery element  150  (in other embodiments the detach mechanism  140  comprises a male screw thread connected to the flexible joint  130 , configured to connect to a female screw thread on the delivery element  150 ). 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 6A . Flexible elongate material  310  allows the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, the delivery element  150  may be rotated to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 6B  shows an embodiment of the embolization system  100  described with respect to  FIG. 1 . In the embodiment of  FIG. 6B , the flexible joint  130  is provided proximally to the detach mechanism  140 . The flexible joint may comprise a flexible material  310  (for example a wire, thread or ribbon). The flexible material  310  may be made of any suitable material such as a polymer or metal. The flexible material  310  is connected to the detach mechanism  140  at a distal end and the elongate element  150  at a proximal end. The flexible material  310  may be crimped to the detach mechanism  140  and the delivery element  150  by crimped hypotubes  312 . Alternatively, the flexible material  310  may be attached by adhesive or welding. Detach mechanism  140  comprises a female screw thread  140   b  formed on the proximal fixing element  122  or directly on the skeleton  114 , which is configured to connect to a male screw thread  140   a  connected to flexible joint  130  (in other embodiments the detach mechanism  140  comprises a male screw thread connected to the embolization device  110 , configured to connect to a female screw thread connected to the delivery element  150  via flexible joint  130 ). 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 6B . The flexible material  310  allows the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, the delivery element  150  may be rotated to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 6C  shows an embodiment of the embolization system  100  described with respect to  FIG. 1 . In the embodiment of  FIG. 6C , the flexible joint  130  is provided distally to the detach mechanism  140 . The flexible joint  130  may comprise a flexible material  310  (for example a wire, thread or ribbon). The flexible material  310  may be made of any suitable material such as a polymer or metal. The flexible material  310  is connected to the detach mechanism  140  at a proximal end and the embolization device  110  (proximal fixing element  122  or skeleton  112 ) at a distal end. The flexible material  310  may be crimped to the detach mechanism  140  and the embolization device by crimped hypotubes  312  or by adhesive or welding. Detach mechanism  140  may comprise an electrolytic element  145  connecting the flexible joint  130  and the delivery element  150 . The electrolytic element  145  is electrically connected to a proximal end of the embolization system  100 , and is operable to disintegrate by electrolysis in the body lumen to detach the embolization device  110  from the delivery element  150 . By applying an electric current to the electrolytic element, at a current amplitude, a voltage and for a duration of time, such that the electrical energy supplied to the electrolytic element is above a disintegration energy of the electrolytic element, the delivery element  150  is detached from the embolization device  110 . The delivery element  150  may be electrically conductive itself or a conductive wire (not shown) may be provided that runs along the length of the delivery element  150 . The electrolytic element  145  may be formed of any material configured to disintegrate by electrolysis in the body lumen upon application of an electric current. Suitable materials include platinum, stainless steel, nitinol and cobalt chromium. The electric current applied may be a positive direct current. A corresponding electrode may be provided proximal to the location of the embolization device  110  to complete the circuit, for example inside the bodily lumen adjacent the electrolytic element or on the surface of the patient proximal to the location of the embolization device  110 . It is noted that in some embodiments, the flexible material  310  may be formed of the electrolytic material  145 , the flexible joint  130  thus acting as both the flexible joint  130  and the detach mechanism  140 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 6C . The flexible material  310  allows the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, electric current is applied to the electrolytic element  145  to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 6D  shows another embodiment of the embolization system described with respect to  FIG. 1 . In the embodiment of  FIG. 6D , the flexible joint  130  is provided proximally to the detach mechanism  140 . The flexible joint  130  may comprise a flexible material  310  (for example a wire, thread or ribbon). The flexible material  310  may be made of any suitable material such as a polymer or metal. The flexible material  310  is connected to the delivery element  150  at a proximal end and the detach mechanism  140  at a distal end. The flexible material  310  may be crimped to the detach mechanism  140  and the delivery element  150  by crimped hypotubes  312  or by adhesive or welding. Detach mechanism  140  may comprise an electrolytic element  145  connecting the flexible joint  130  and the embolization device  110 . The flexible material  310  may be formed on the electrolytic element  145  or may itself be made of electrolytic material such that it acts as both the joint  130  and the electrolytic element  145 . The electrolytic element  145  is electrically connected to a proximal end of the embolization system  100 , and is operable to disintegrate by electrolysis in the body lumen to detach the embolization device  110  from the delivery element  150 . By applying an electric current to the electrolytic element, at a current amplitude, a voltage and for a duration of time, such that the electrical energy supplied to the electrolytic element is above a disintegration energy of the electrolytic element, the delivery element  150  is detached from the embolization device  110 . The delivery element  150  may be electrically conductive itself or a conductive wire (not shown) may be provided that runs along the length of the delivery element  150 . The flexible material  310  may be electrically conductive itself or a flexible conductive wire may extend across the joint  130  to electrically connect the electrolytic element  145 . The electrolytic element  145  may be formed of any material configured to disintegrate by electrolysis in the body lumen upon application of an electric current. Suitable materials include platinum, stainless steel, nitinol and cobalt chromium. The electric current applied may be a positive direct current. A corresponding electrode may be provided proximal to the location of the embolization device  110  to complete the circuit, for example inside the bodily lumen adjacent the electrolytic element or on the surface of the patient proximal to the location of the embolization device  110 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 6D . The flexible material  310  allows the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, electric current is applied to the electrolytic element  145  to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 7A  shows an embodiment of the embolization system  100  described with respect to  FIG. 1 . In the embodiment of  FIG. 7A , the flexible joint  130  is provided distally to the detach mechanism  140 . The flexible joint  130  may comprise an articulating joint, which comprises an interlocking chain of loops  300   a ,  300   b  and  314 . The interlocking chain of loops  300   a ,  300   b  and  314  may be made of any suitable material such as a polymer or metal. Loop  300   b  is connected to the embolization device  110  and loop  300   a  is connected to the detach mechanism  140 . Loops  300   a  and  300   b  are connected to each other via intermediate loop  314 . Detach mechanism  140  may comprise a female screw thread  140   b  which is configured to connect to a male screw thread  140   a  on a delivery element  150  (in other embodiments the detach mechanism  140  comprises a male screw thread connected to the flexible joint  130 , configured to connect to a female screw thread on the delivery element  150 ). The loop  300   b  may be formed on the proximal fixing element  122  or may be formed directly on the skeleton  114  of embolization device  110 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 7A . The interlocking loops  300   a ,  300   b  and  314  allow the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, the delivery element  150  may be rotated to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 7B  shows another embodiment of the embolization system  100  described with respect to  FIG. 1 . In the embodiment of  FIG. 7B , the flexible joint  130  is provided proximally to the detach mechanism  140 . The flexible joint  130  may comprise an articulating joint, which comprises an interlocking chain of loops  300   a ,  300   b  and  314 . The interlocking chain of loops  300   a ,  300   b  and  314  may be made of any suitable material such as a polymer or metal. Loop  300   b  is connected to the detach mechanism  140  and loop  300   a  is connected to the delivery element  150 . Detach mechanism  140  may comprise a female screw thread  140   b  connected to embolization device  110  which is configured to connect to a male screw thread  140   a  connected to loop  300   b  (in other embodiments the detach mechanism  140  comprises a male screw thread connected to the embolization device  110 , configured to connect to a female screw thread connected to the loop  300   b ). the female screw thread  140   b  may be formed on the proximal fixing element  122  or may be formed directly on the skeleton  114  of embolization device  110 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 7B . The interlocking loops  300   a ,  300   b  and  314  allow the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, the delivery element  150  may be rotated to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 7C  shows another embodiment of the embolization system described with respect to  FIG. 1 . In the embodiment of  FIG. 7C , the flexible joint  130  is provided distally to the detach mechanism  140 . The flexible joint  130  may comprise an articulating joint, which comprises interlocking loops  300   a ,  300   b  and  314 . The interlocking chain of loops  300   a ,  300   b  and  314  may be made of any suitable material such as a polymer or metal. Loop  300   b  is connected to the embolization device  110  and loop  300   a  is connected to the detach mechanism  140 . The loop  300   b  may be formed on the proximal fixing element  122  or may be formed directly on the skeleton  114  of embolization device  110 . Detach mechanism  140  may comprise an electrolytic element  145  connecting the flexible joint  130  and the delivery element  150 . The electrolytic element  145  is electrically connected to a proximal end of the embolization system  100 , and is operable to disintegrate by electrolysis in the body lumen to detach the embolization device  110  from the delivery element  150 . By applying an electric current to the electrolytic element, at a current amplitude, a voltage and for a duration of time, such that the electrical energy supplied to the electrolytic element is above a disintegration energy of the electrolytic element, the delivery element  150  is detached from the embolization device  110 . The delivery element  150  may be electrically conductive itself or a conductive wire (not shown) may be provided that runs along the length of the delivery element  150 . The electrolytic element  145  may be formed of any material configured to disintegrate by electrolysis in the body lumen upon application of an electric current. Suitable materials include platinum, stainless steel, nitinol and cobalt chromium. The electric current applied may be a positive direct current. A corresponding electrode may be provided proximal to the location of the embolization device  110  to complete the circuit, for example inside the bodily lumen adjacent the electrolytic element or on the surface of the patient proximal to the location of the embolization device  110 . It is noted that in some embodiments, loops  300   a ,  300   b  and/or  314  may be formed of the electrolytic material  145 , thus acting as both the flexible joint  130  and the detach mechanism  140 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 7C . The interlocking loops  300   a ,  300   b  and  314  allow the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, electric current is applied to the electrolytic element  145  to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 7D  shows another embodiment of the embolization system described with respect to  FIG. 1 . In the embodiment of  FIG. 7D , the flexible joint  130  is provided proximally to the detach mechanism  140 . The flexible joint  130  may comprise an articulating joint, which comprises interlocking loops  300   a ,  300   b  and  314 . The interlocking chain of loops  300   a ,  300   b  and  314  may be made of any suitable material such as a polymer or metal. Detach mechanism  140  may comprise an electrolytic element  145  connecting the flexible joint  130  and the embolization device  110 . Loop  300   b  may be formed on the electrolytic element  145  or one or more of loops  300   a ,  300   b ,  314  may themselves be made of electrolytic material such that it acts as both the joint  130  and the electrolytic element  145 . The electrolytic element  145  is electrically connected to a proximal end of the embolization system  100 , and is operable to disintegrate by electrolysis in the body lumen to detach the embolization device  110  from the delivery element  150 . By applying an electric current to the electrolytic element, at a current amplitude, a voltage and for a duration of time, such that the electrical energy supplied to the electrolytic element is above a disintegration energy of the electrolytic element, the delivery element  150  is detached from the embolization device  110 . The delivery element  150  may be electrically conductive itself or a conductive wire (not shown) may be provided that runs along the length of the delivery element  150 . The loops  300   a ,  300   b  and  314  may be electrically conductive themselves or a flexible conductive wire may extend across the joint  130  to electrically connect the electrolytic element  145 . The electrolytic element  145  may be formed of any material configured to disintegrate by electrolysis in the body lumen upon application of an electric current. Suitable materials include platinum, stainless steel, nitinol and cobalt chromium. The electric current applied may be a positive direct current. A corresponding electrode may be provided proximal to the location of the embolization device  110  to complete the circuit, for example inside the bodily lumen adjacent the electrolytic element or on the surface of the patient proximal to the location of the embolization device  110 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 7D . The interlocking loops  300   a ,  300   b  and  314  allow the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, electric current is applied to the electrolytic element  145  to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 8A  shows an embodiment of the embolization system  100  described with respect to  FIG. 1 . In the embodiment of  FIG. 8A , the flexible joint  130  is provided distally to the detach mechanism  140 . The flexible joint  130  may comprise an articulating joint, which comprises loops  300   a  and  300   b  connected via a connecting piece  316  comprising connecting arms which inhibit the loops  300   a  and  300   b  from being separated. The loops  300   a ,  300   b  and connecting piece  316  may be made of any suitable material such as a polymer or metal. Loop  300   b  is connected to the embolization device  110  and loop  300   a  is connected to the detach mechanism  140 . Detach mechanism  140  may comprise a female screw thread  140   b  which is configured to connect to a male screw thread  140   a  on a delivery element  150  (in other embodiments the detach mechanism  140  comprises a male screw thread connected to the flexible joint  130 , configured to connect to a female screw thread on the delivery element  150 ). The loop  300   b  may be formed on the proximal fixing element  122  or may be formed directly on the skeleton  114  of embolization device  110 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 8A . The interlocking loops  300   a ,  300   b  and connecting piece  316  allow the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, the delivery element  150  may be rotated to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 8B  shows another embodiment of the embolization system  100  described with respect to  FIG. 1 . In the embodiment of  FIG. 8B , the flexible joint  130  is provided proximally to the detach mechanism  140 . The flexible joint  130  may comprise an articulating joint, which comprises loops  300   a  and  300   b  connected via a connecting piece  316  comprising connecting arms which inhibit the loops  300   a  and  300   b  from being separated. The loops  300   a ,  300   b  and connecting piece  316  may be made of any suitable material such as a polymer or metal. Loop  300   b  is connected to the detach mechanism  140  and loop  300   a  is connected to the delivery element  150 . Detach mechanism  140  may comprise a female screw thread  140   b  connected to embolization device  110  which is configured to connect to a male screw thread  140   a  connected to loop  300   b  (in other embodiments the detach mechanism  140  comprises a male screw thread connected to the embolization device  110 , configured to connect to a female screw thread connected to the loop  300   b ). the female screw thread  140   b  may be formed on the proximal fixing element  122  or may be formed directly on the skeleton  114  of embolization device  110 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 8B . The interlocking loops  300   a ,  300   b  and connecting piece  316  allow the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, the delivery element  150  may be rotated to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 8C  shows another embodiment of the embolization system described with respect to  FIG. 1 . In the embodiment of  FIG. 8C , the flexible joint  130  is provided distally to the detach mechanism  140 . The flexible joint  130  may comprise an articulating joint, which comprises loops  300   a  and  300   b  connected via a connecting piece  316  comprising connecting arms which inhibit the loops  300   a  and  300   b  from being separated. The loops  300   a ,  300   b  and connecting piece  316  may be made of any suitable material such as a polymer or metal. Loop  300   b  is connected to the embolization device  110  and loop  300   a  is connected to the detach mechanism  140 . The loop  300   b  may be formed on the proximal fixing element  122  or may be formed directly on the skeleton  114  of embolization device  110 . Detach mechanism  140  may comprise an electrolytic element  145  connecting the flexible joint  130  and the delivery element  150 . The electrolytic element  145  is electrically connected to a proximal end of the embolization system  100 , and is operable to disintegrate by electrolysis in the body lumen to detach the embolization device  110  from the delivery element  150 . By applying an electric current to the electrolytic element, at a current amplitude, a voltage and for a duration of time, such that the electrical energy supplied to the electrolytic element is above a disintegration energy of the electrolytic element, the delivery element  150  is detached from the embolization device  110 . The delivery element  150  may be electrically conductive itself or a conductive wire (not shown) may be provided that runs along the length of the delivery element  150 . The electrolytic element  145  may be formed of any material configured to disintegrate by electrolysis in the body lumen upon application of an electric current. Suitable materials include platinum, stainless steel, nitinol and cobalt chromium. The electric current applied may be a positive direct current. A corresponding electrode may be provided proximal to the location of the embolization device  110  to complete the circuit, for example inside the bodily lumen adjacent the electrolytic element or on the surface of the patient proximal to the location of the embolization device  110 . It is noted that in some embodiments, loops  300   a ,  300   b  and/or connecting piece  316  may be formed of the electrolytic material  145 , thus acting as both the flexible joint  130  and the detach mechanism  140 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 8C . The interlocking loops  300   a ,  300   b  and connecting piece  316  allow the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, electric current is applied to the electrolytic element  145  to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 8D  shows another embodiment of the embolization system described with respect to  FIG. 1 . In the embodiment of  FIG. 8D , the flexible joint  130  is provided proximally to the detach mechanism  140 . The flexible joint  130  may comprise an articulating joint, which comprises loops  300   a  and  300   b  connected via a connecting piece  316  comprising connecting arms which inhibit the loops  300   a  and  300   b  from being separated. The loops  300   a ,  300   b  and connecting piece  316  may be made of any suitable material such as a polymer or metal. Detach mechanism  140  may comprise an electrolytic element  145  connecting the flexible joint  130  and the embolization device  110 . Loop  300   b  may be formed on the electrolytic element  145  or one or more of loops  300   a ,  300   b , and connecting piece  316  may themselves be made of electrolytic material such that it acts as both the joint  130  and the electrolytic element  145 . The electrolytic element  145  is electrically connected to a proximal end of the embolization system  100 , and is operable to disintegrate by electrolysis in the body lumen to detach the embolization device  110  from the delivery element  150 . By applying an electric current to the electrolytic element, at a current amplitude, a voltage and for a duration of time, such that the electrical energy supplied to the electrolytic element is above a disintegration energy of the electrolytic element, the delivery element  150  is detached from the embolization device  110 . The delivery element  150  may be electrically conductive itself or a conductive wire (not shown) may be provided that runs along the length of the delivery element  150 . The loops  300   a ,  300   b  and connecting piece  316  may be electrically conductive themselves or a flexible conductive wire may extend across the joint  130  to electrically connect the electrolytic element  145 . The electrolytic element  145  may be formed of any material configured to disintegrate by electrolysis in the body lumen upon application of an electric current. Suitable materials include platinum, stainless steel, nitinol and cobalt chromium. The electric current applied may be a positive direct current. A corresponding electrode may be provided proximal to the location of the embolization device  110  to complete the circuit, for example inside the bodily lumen adjacent the electrolytic element or on the surface of the patient proximal to the location of the embolization device  110 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 8D . The interlocking loops  300   a ,  300   b  and connecting piece  316  allow the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, electric current is applied to the electrolytic element  145  to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 9A  shows an embodiment of the embolization system  100  described with respect to  FIG. 1 . In the embodiment of  FIG. 9A , the flexible joint  130  is provided distally to the detach mechanism  140 . The flexible joint  130  may comprise a flexible tube  320 . The flexible tube  320  may be made of any suitable material such as a polymer or metal. The flexible tube  320  is connected to the detach mechanism  140  at a proximal end and the embolization device  110  (proximal fixing element  122  or skeleton  112 ) at a distal end. The flexible tube  320  may be made of, for example, a heat-shrinkable material and heat-shrunk a distal end of the detach mechanism  140  and a proximal end of the embolization device  110 . Alternatively, the flexible tube  320  may be attached by adhesive or welding. Detach mechanism  140  may comprise a female screw thread  140   b  which is configured to connect to a male screw thread  140   a  on a delivery element  150  (in other embodiments the detach mechanism  140  comprises a male screw thread connected to the flexible joint  130 , configured to connect to a female screw thread on the delivery element  150 ). 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 9A . Flexible tube  320  allows the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, the delivery element  150  may be rotated to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 9B  shows an embodiment of the embolization system  100  described with respect to  FIG. 1 . In the embodiment of  FIG. 9B , the flexible joint  130  is provided proximally to the detach mechanism  140 . The flexible joint may comprise a flexible tube  320 . The flexible tube  320  may be made of any suitable material such as a polymer or metal. The flexible tube  320  is connected to the delivery element  150  at a proximal end and the detach mechanism  140  at a distal end. The flexible tube  320  may be made of, for example, a heat-shrinkable material and heat-shrunk a distal end of the delivery element  150  and a proximal end of the detach mechanism  140 . Alternatively, the flexible tube  320  may be attached by adhesive or welding. Detach mechanism  140  may comprise a female screw thread  140   b  formed on the proximal fixing element  122  or directly on the skeleton  114 , which is configured to connect to a male screw thread  140   a  connected to flexible joint  130  (in other embodiments the detach mechanism  140  comprises a male screw thread connected to the embolization device  110 , configured to connect to a female screw thread connected to the delivery element  150  via flexible joint  130 ). 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 9B . The flexible tube  320  allows the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, the delivery element  150  may be rotated to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 9C  shows an embodiment of the embolization system  100  described with respect to  FIG. 1 . In the embodiment of  FIG. 9C , the flexible joint  130  is provided distally to the detach mechanism  140 . The flexible joint  130  may comprise a flexible tube  320 . The flexible tube  320  may be made of any suitable material such as a polymer or metal. The flexible tube  320  is connected to the detach mechanism  140  at a proximal end and the embolization device  110  (proximal fixing element  122  or skeleton  112 ) at a distal end. The flexible tube  320  may be made of, for example, a heat-shrinkable material and heat-shrunk a distal end of the detach mechanism  140  and a proximal end of the embolization device  110 . Alternatively, the flexible tube  320  may be attached by adhesive or welding. Detach mechanism  140  may comprise an electrolytic element  145  connecting the flexible joint  130  and the delivery element  150 . The electrolytic element  145  is electrically connected to a proximal end of the embolization system  100 , and is operable to disintegrate by electrolysis in the body lumen to detach the embolization device  110  from the delivery element  150 . By applying an electric current to the electrolytic element, at a current amplitude, a voltage and for a duration of time, such that the electrical energy supplied to the electrolytic element is above a disintegration energy of the electrolytic element, the delivery element  150  is detached from the embolization device  110 . The delivery element  150  may be electrically conductive itself or a conductive wire (not shown) may be provided that runs along the length of the delivery element  150 . The electrolytic element  145  may be formed of any material configured to disintegrate by electrolysis in the body lumen upon application of an electric current. Suitable materials include platinum, stainless steel, nitinol and cobalt chromium. The electric current applied may be a positive direct current. A corresponding electrode may be provided proximal to the location of the embolization device  110  to complete the circuit, for example inside the bodily lumen adjacent the electrolytic element or on the surface of the patient proximal to the location of the embolization device  110 . It is noted that in some embodiments, the flexible tube  320  may be formed at least partially of the electrolytic material  145  (for example the flexible tube  320  may be made of the electrolytic material  145  and comprise a plurality of slots in the tube  320  to facilitate bending of the tube), the flexible joint  130  thus acting as both the flexible joint  130  and the detach mechanism  140 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 9C . The flexible tube  320  allows the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, electric current is applied to the electrolytic element  145  to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
       FIG. 9D  shows another embodiment of the embolization system described with respect to  FIG. 1 . In the embodiment of  FIG. 9D , the flexible joint  130  is provided proximally to the detach mechanism  140 . The flexible joint  130  may comprise a flexible tube  320 . The flexible tube  320  may be made of any suitable material such as a polymer or metal. The flexible tube  320  is connected to the delivery element  150  at a proximal end and the detach mechanism  140  at a distal end. The flexible tube  320  may be made of, for example, a heat-shrinkable material and heat-shrunk a distal end of the delivery element  150  and a proximal end of the detach mechanism  140 . Alternatively, the flexible tube  320  may be attached by adhesive or welding. Detach mechanism  140  may comprise an electrolytic element  145  connecting the flexible joint  130  and the embolization device  110 . The flexible tube  320  may be formed on the electrolytic element  145  or may itself be made of electrolytic material as in the case of the embodiment described with respect to  FIG. 9C , such that it acts as both the joint  130  and the electrolytic element  145 . The electrolytic element  145  is electrically connected to a proximal end of the embolization system  100 , and is operable to disintegrate by electrolysis in the body lumen to detach the embolization device  110  from the delivery element  150 . By applying an electric current to the electrolytic element, at a current amplitude, a voltage and for a duration of time, such that the electrical energy supplied to the electrolytic element is above a disintegration energy of the electrolytic element, the delivery element  150  is detached from the embolization device  110 . The delivery element  150  may be electrically conductive itself or a conductive wire (not shown) may be provided that runs along the length of the delivery element  150 . The flexible tube  320  may be electrically conductive itself or a flexible conductive wire may extend across the joint  130  to electrically connect the electrolytic element  145 . The electrolytic element  145  may be formed of any material configured to disintegrate by electrolysis in the body lumen upon application of an electric current. Suitable materials include platinum, stainless steel, nitinol and cobalt chromium. The electric current applied may be a positive direct current. A corresponding electrode may be provided proximal to the location of the embolization device  110  to complete the circuit, for example inside the bodily lumen adjacent the electrolytic element or on the surface of the patient proximal to the location of the embolization device  110 . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 9D . The flexible tube  320  allows the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, electric current is applied to the electrolytic element  145  to release the embolization device  110  from the delivery element  150  and the delivery element  150  and delivery catheter  200  can be removed from the bodily lumen as illustrated in  FIG. 2C . 
     In embodiments where the detach mechanism is provided distally to the flexible joint, advantageously the flexible joint is removed from the bodily lumen upon deployment, which may be beneficial if the flexible joint has a risk of detaching from the embolization device when deployed in the lumen. 
       FIG. 19A  shows an embodiment of the embolization system  100  described with respect to  FIG. 1 . In the embodiment of  FIG. 19A , the flexible joint  130  is provided distally to the detach mechanism  140 . In the illustrated embodiment, the flexible joint  130  may comprise an articulating joint, which comprises interlocking loops  300   a  and  300   b . In other embodiments, the flexible joint  130  may comprise any of the flexible joints  130  described with reference to  FIGS. 4A to 9D . Loop  300   b  is connected to the embolization device  110  and loop  300   a  is connected to the detach mechanism  140 . The interlocking loops  300   a ,  300   b  may be made of any suitable material such as a polymer or metal. The loop  300   b  may be formed on the proximal fixing element  122  or may be formed directly on the skeleton  112  of embolization device  110 . Detach mechanism  140  may include a breakable detachment element  556  connecting a proximal portion of flexible joint  130  (in the illustrated embodiment loop  300   a ) and delivery element  150 . The breakable detachment element  556  may be fixed to the proximal portion of flexible joint  130  and distal portion of delivery element  150  by any suitable attachment means, such as by welding, adhesive or crimping. The breakable detachment element  556  may be any suitable breakable detachment element  556 , such as any of those described with reference to  FIGS. 20A to 20C . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 19A . The interlocking loops  300   a  and  300   b  allow the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, the delivery element  150  may be rotated by a predetermined amount, in either direction, about the longitudinal axis of the delivery element  150 . The rotation can be effected by a user at the proximal end of the delivery wire, manually or by using any suitable rotation mechanism. As the embolization device  110  is anchored to the bodily lumen, relative rotation between the delivery element  150  and the embolization device  110  occurs. This rotation results in an increased amount of torque being applied at the detachment mechanism  140 . The breakable detachment element  556  is configured to break preferentially before the delivery element  150  nor the flexible joint  130  breaks. Once sufficient torque is applied to the detachment mechanism  140 , the breakable detachment element  556  breaks. In any of the embodiments disclosed herein, the force required to break the breakable detachment element  556  can be selected to be low enough such that the embolization device  110  is not dislodged or moved from the anchored position in the bodily lumen when applying the force to break the breakable detachment element  556 . This breaking force can be selected based on the anchoring properties of the particular embolization device  110  being used. 
       FIG. 19B  shows an embodiment of the embolization system  100  described with respect to  FIG. 1 . In the embodiment of  FIG. 19B , the flexible joint  130  is provided distally to the detach mechanism  140 . In the illustrated embodiment, the flexible joint  130  may comprise an articulating joint, which comprises interlocking loops  300   a  and  300   b . In other embodiments, the flexible joint  130  may comprise any of the flexible joints  130  described with reference to  FIGS. 4A to 9D . Loop  300   b  is connected to the embolization device  110  and loop  300   a  is connected to the detach mechanism  140 . The interlocking loops  300   a ,  300   b  may be made of any suitable material such as a polymer or metal. The loop  300   b  may be formed on the proximal fixing element  122  or may be formed directly on the skeleton  112  of embolization device  110 . Detach mechanism  140  may include a breakable detachment element  556  connecting a proximal portion of embolization device  110  and a distal portion of the flexible joint  130  (in the illustrated embodiment loop  300   b ). The breakable detachment element  556  may be fixed to the proximal portion of embolization device  110  and distal portion of the flexible joint  130  by any suitable attachment means, such as by welding, adhesive or crimping. The breakable detachment element  556  may be any suitable breakable detachment element  556 , such as any of those described with reference to  FIGS. 20A to 20C . 
     The deployment method disclosed with respect to  FIGS. 2A to 2C  can be used for the embolization system  100  shown in  FIG. 19A . The interlocking loops  300   a  and  300   b  allow the embolization device  110  to tilt with respect to the delivery element  150  in configurations such as that shown in  FIG. 2B . When the embolization device  110  is correctly positioned in the bodily lumen, the delivery element  150  may be rotated by a predetermined amount, in either direction, about the longitudinal axis of the delivery element  150 . The rotation can be effected by a user at the proximal end of the delivery wire, manually or by using any suitable rotation mechanism. As the embolization device  110  is anchored to the bodily lumen, relative rotation between the delivery element  150  and the embolization device  110  occurs. This rotation results in an increased amount of torque being applied at the detachment mechanism  140  (the rotation of the delivery element  150  is transmitted to the breakable detachment element by the flexible joint  130 ). The breakable detachment element  556  is configured to break preferentially before the delivery element  150  nor the flexible joint  130  breaks. Once sufficient torque is applied to the detachment mechanism  140 , the breakable detachment element  556  breaks. In any of the embodiments disclosed herein, the force required to break the breakable detachment element  556  can be selected to be low enough such that the embolization device  110  is not dislodged or moved from the anchored position in the bodily lumen when applying the force to break the breakable detachment element  556 . This breaking force can be selected based on the anchoring properties of the particular embolization device  110  being used. 
     It is noted that whilst in the embodiments described with reference to  FIGS. 19A and 19B  (as well as  FIGS. 3A to 9D ) the flexible joint  130  and detach mechanism  140  are provided as separate elements, it may be that the delivery element  150  and the proximal end of the embolization device  110  are connected by a singular breakable detachment element  556  which is also flexible such that it additionally acts flexible joint  130 , i.e. having a higher flexibility than the embolization device for allowing the embolization device to tilt with respect to the delivery element when the delivery element is connected to the embolization device. In such embodiments, the breakable detachment element  556  directly connects the delivery element  150  and the proximal end of the embolization device  110 . It may be preferred to provide the flexible joint  130  and detach mechanism  140  as separate elements, wherein the flexible joint  130  is configured to bend more than detach mechanism  140  when a bending force is applied to the embolization system, so that the detach mechanism  140  does not break prematurely. 
       FIG. 20A  shows a breakable detachment element  556  for an embolization system according to one or more embodiments. The breakable detachment element  556  of  FIG. 20A  may comprise a portion  557   b  that is a different material from the material of both proximal element  557   a  and distal element  557   c  which the breakable detachment element  556  connects (for example, in the illustrated embodiment of  FIG. 19A , the proximal element  557   a  is the delivery element  150  and the distal element  557   c  is proximal portion of flexible joint  130 ; in the illustrated embodiment of  FIG. 19B , the proximal element  557   a  is the distal portion of flexible joint  130  and the distal element  557   c  is a proximal portion of the embolization device  110 ). In particular, the material of portion  557   b  may be selected to be a material which is less stiff than the material of the proximal element  557   a  and the distal element  557   c . As such, any torque applied to the system (for example at delivery element  150 ) results in a larger amount of twist at the portion  557   b . Further, when provided as separate elements, the material of portion  557   a  may be selected so that the torque required to break the portion  557   a  is lower than the torque required to break the flexible joint  130 . After a sufficient amount of torque is applied to the delivery wire  150 , the portion  557   b  breaks and the stem  110  is separated from the delivery wire  150 . The amount of torque required to break the portion  557   b  (i.e. the amount of rotation of the delivery wire  150 ) may be determined by the material properties of the portion  557   b , the proximal element  557   a  and the distal element  557   c . The materials can be selected such that the portion  557   b  is configured to shear upon an amount of rotation of the delivery element  150  that is above the expected amount of relative rotation of the device during the delivery process (due to the tortuous path taken by the device through the delivery catheter). For example, the material of the portion  557   b  may be selected from Nylon, PTFE, or Cobalt-chrome, and the materials of the proximal element  557   a  and the distal element  557   c  may be selected from nitinol or Cobalt-chrome (such that the material of the portion  557   b  differs from both). 
       FIG. 20B  shows a breakable detachment element  556  according to one or more embodiments. The detachment element  556  of  FIG. 20B  may comprise a necked portion  558 . The necked portion  558  may have a radial extent selected such that the necked portion preferentially breaks when a torque is applied to the embolization system via delivery element  150 . The necked portion may have a radial extent that is less than the radial extent of the delivery element  150 . The necked portion is prone to a high amount of twist when torque is applied to the delivery element  150 . As a result, after a sufficient amount of torque is applied to the delivery element  150 , the necked portion  558  breaks and the embolization device  110  is separated from the delivery element  150 . The amount of torque required to break the necked portion  558  (i.e. the amount of rotation of the delivery element  150 ) may be determined by the dimensions of the necked portion  558  and the material properties of the necked portion  558 . The dimensions and material properties can be selected such that the necked portion  558  is configured to shear upon an amount of rotation of the delivery element  150  that is above the expected amount of relative rotation of the device during the delivery process (due to the tortuous path taken by the device through the delivery catheter). In embodiments where the flexible joint  130  is provided as a separate element, the shear force required to break the necked portion  558  is also higher than the shear force required to break the flexible joint  130 . For example, the detachment element may be made of Nylon, PTFE, or Cobalt-chrome and a cross-sectional area of the necked portion may be selected to be 50% or less of the cross-sectional area of the delivery element  150 . The necked portion  558  may be provided in an element which is then connected to the relevant proximal and distal elements (for example, in the case of embodiment such as  FIG. 19A , the delivery element  150  and proximal portion of flexible joint  130 ; in the case of embodiments such as  FIG. 19B , the distal portion of flexible joint  130  and proximal portion of embolization device  110 ). In other embodiments where the detach mechanism  140  is provided proximal to the flexible joint  130  (e.g.  FIG. 19A ) or where the breakable detach element  556  is also the flexible joint  130 , the necked portion  558  may be provided directly on the delivery element  150  (for example machined or otherwise formed on delivery element  150 ) and the delivery element  150  may be connected directly to the flexible joint  130  (or embolization device  110  where the breakable detach mechanism is also the flexible joint  130 ). 
       FIG. 20C  shows a breakable detachment element  556  according to one or more embodiments. The breakable detachment element  556  of  FIG. 20C  may comprise a weakening structure  559 . The weakening structure  559  may comprise an irregularity such that the shearing force required to break it is lower than the shearing force required to break the other elements of the embolization system. As illustrated in  FIG. 20C , the weakening structure  559  may be a fracture. The fracture may have a radial extent that is less than the radial extent of the delivery element  150 . The weakening structure  559  is prone to a high amount of twist when torque is applied to the delivery element  150 . As a result, after a sufficient amount of torque is applied to the delivery element  150 , the weakening structure  559  breaks and the embolization device  110  is separated from the delivery element  150 . The amount of torque required to break the weakening structure  559  (i.e. the amount of rotation of the delivery element  150 ) may be determined by the dimensions of the fracture. The relative dimensions can be selected such that the weakening structure  559  is configured to shear upon an amount of rotation of the delivery wire  150  that is above the expected amount of relative rotation of the device during the delivery process (due to the tortuous path taken by the device through the delivery catheter). The weakening structure may be configured to preferential break before the other elements of the embolization system (i.e. at a shear force which is lower than the shear force required to break the other elements of the embolization system). In embodiments where the flexible joint  130  is provided as a separate element, the shear force required to break the breakable detachment element  556  is lower than that of the flexible joint  130 . The detachment element may be made of Nylon, PTFE, or Cobalt-chrome and may be the same or different material to the delivery element  150  and/or flexible joint  130  and/or embolization device  110 . A cross-sectional area of the breakable detachment element  559  may be selected to be 50% or less of the cross-sectional area of the delivery element  150 . The weakening structure  559  may be provided on an element which is then connected to the relevant proximal and distal elements (for example, in the case of embodiment such as  FIG. 19A , the delivery element  150  and proximal portion of flexible joint  130 ; in the case of embodiments such as  FIG. 19B , the distal portion of flexible joint  130  and proximal portion of embolization device  110 ). In other embodiments where the detach mechanism  140  is provided proximal to the flexible joint  130  (e.g.  FIG. 19A ) or where the breakable detach element  556  is also the flexible joint  130 , the weakening structure  559  may be provided directly on the delivery element  150  (for example machined or otherwise formed on delivery element  150 ) and the delivery element  150  may be connected directly to the flexible joint  130  or embolization device  110  (or embolization device  110  where the breakable detach mechanism is also the flexible joint  130 ). 
     In some embodiments, the breakable detachment element  556  may comprise any two or all three of the portion  557   b , necked portion  558  and weakening structure  559 . 
     In any of the embodiments of the embolization system, the detach mechanism may instead be comprised in any of the delivery systems disclosed herein with reference to  FIGS. 10A to 17B . 
       FIG. 10A  shows a delivery system  400  for delivering and deploying an implant, such as the embolization device  110  described with reference to  FIG. 1 , an embolization device such as that described in European patents EP 2 967 569 B1 or EP 3 193 743 B1, or am embolization coil, to a bodily lumen according to one or more embodiments. The delivery system may generally include a delivery element  410  configured to extend through a lumen of a delivery catheter, a detach mechanism  420  mounted to a distal portion of the delivery element  410 , and an actuating mechanism  430 . The delivery element  410 , detach mechanism  420  and actuating mechanism  430  may be made of any suitable material such as a polymer or metal. The detach mechanism  420  has a first configuration in which the detach mechanism  420  is configured to grip the implant, as shown in  FIG. 10A  and  FIGS. 11A and 11B , and a second configuration in which the detach mechanism  420  is configured to release the implant, as shown in  FIG. 10B  and  FIG. 11C . The actuating mechanism  430  is configured to extend through the lumen of the delivery catheter to the detach mechanism  420 . In  FIG. 10A  the actuating mechanism  430  extends through a lumen of the delivery element  410 . The delivery element  410  prevents the actuating mechanism  420  from buckling. In other embodiments, the actuating mechanism  420  may be external to the delivery element  410 . The actuating mechanism  420  is movable between a first position and a second position. The first position is shown in  FIG. 10A . 
       FIG. 10B  shows the delivery system  400  of  FIG. 10A  when the actuating mechanism  420  is in the second position. Moving the actuating mechanism  420  from the first position to the second position (i.e. in direction D) changes the detach mechanism  420  from the first configuration to the second configuration. In the particular embodiment shown in FIGS.  10 A and  10 B, the detach mechanism  420  comprises a pair of gripping elements  420   a ,  420   b  hingedly mounted to delivery element  410  via hinges  422   a ,  422   b . The actuating mechanism  420  is coupled to the gripping elements  420   a ,  420   b  such that movement of the actuating mechanism  420  distally to the second position causes the gripping elements  420   a ,  420   b  to pivot about hinges  422   a ,  422   b  so that they open. The actuating mechanism  420  may be coupled to the gripping elements  420   a ,  420   b  by friction or the actuating mechanism  420  and gripping elements  420   a ,  420   b  may comprises interlocking teeth  470   a ,  470   b ,  475   a ,  475   b  (as illustrated in  FIGS. 17A and 17B ) which engage so that movement of the actuating mechanism  420  results in the pivoting motion of the gripping elements  420   a ,  420   b . The gripping elements  420   a ,  420   b  may be claws comprising inwardly facing teeth in order to assist in gripping the medical implant. 
       FIG. 11A  shows the delivery system  400  in a delivery catheter  500  in a bodily lumen  600 . The delivery system is in the first position and grips a proximal end of a medical implant  550 , which in the illustrated embodiment is an embolization coil. The medical implant  550  may comprise a gripping feature  555  having a recess which is configured to receive the inwardly facing teeth of the gripping elements  420   a ,  420   b  inhibit premature release of the medical implant  550  from the delivery system  400 . In the illustrated embodiment of  FIG. 11A , the delivery system  400  has been pushed through the delivery catheter to a distal tip of the delivery catheter  500  so that the medical implant  550  has been delivered into the bodily lumen  600  from the distal tip of the delivery catheter. The medical implant  550  remains gripped by the delivery system  400  so that it can still be retrieved back into the delivery catheter  500  by moving the delivery system  400  proximally relative to the delivery catheter  500 . The delivery catheter  500  may be sized so that the delivery system  400  is unable to move to the second position when the detach mechanism  420  is inside the delivery catheter  500  (i.e. the detach mechanism  420  abuts the inner walls of the delivery catheter  500  so that it is unable to move to the second position). 
       FIG. 11B  shows the delivery system of  FIG. 11A  in a second configuration wherein the delivery catheter  500  and delivery system  400  have been moved with respect to each other (by moving the delivery system  400  distally relative to the delivery catheter  500  and/or moving the delivery catheter  500  proximally relative to the delivery system  400 ), so that the detach mechanism  420  is exterior to the distal tip of the delivery catheter  500 . As such, the detach mechanism  420  is free to move from the first position to the second position. 
       FIG. 11C  shows the delivery system  400  of  FIG. 11B  after the detach mechanism  420  is moved from the first position to the second position. A user of the delivery system  400  actuates a proximal end of the delivery catheter and/or actuating mechanism  420  which is outside of the body to provide the required movement from the first position to the second position. The medical implant  550  is no longer gripped by the delivery system  400 . The delivery system  400  and delivery catheter  500  can be removed from the bodily lumen  600  and the medical implant  550  is deployed. 
     It is noted that the detach mechanism  420  could also be moved from the second position to the first position to re-capture medical implant  550  after deployment. 
       FIG. 12A  shows a delivery system for delivering and deploying an implant to a bodily lumen according to one or more embodiments. The delivery system comprises a delivery element  410  configured to extend through a lumen of a delivery catheter, a detach mechanism  420  mounted to a distal portion of the delivery element  410 , and an actuating mechanism  430 . The delivery element  410 , detach mechanism  420  and actuating mechanism  430  may be made of any suitable material such as a polymer or metal. The detach mechanism  420  has a first configuration in which the detach mechanism  420  is configured to grip the implant, as shown in  FIG. 12A , and a second configuration in which the detach mechanism  420  is configured to release the implant, as shown in  FIG. 12B . The actuating mechanism  430  extends through a lumen of the delivery element  410 . The delivery element  410  prevents the actuating mechanism  420  from buckling. The actuating mechanism  420  is movable between a first position and a second position. The first position is shown in  FIG. 12A . 
     The actuating mechanism  430  of  FIG. 12A  comprises an elongate element  432  (e.g. wire or ribbon) which extends through inner lumen  415  of the delivery element  410 . The detach mechanism  420  comprises a pair of gripping elements  420   a ,  420   b  hingedly mounted to delivery element  410  via hinges  422   a ,  422   b . The pair of gripping elements  420   a ,  420   b  are additionally hingedly connected to a first ends of links  436   a ,  436   b  respectively. The actuating mechanism  420  is hingedly mounted to second ends opposite the first ends of links  436   a ,  436   b  at distal part  434  such that movement of the actuating mechanism  420  distally to the second position causes the links  436   a ,  436   b  to transmit an opening force to the gripping elements  420   a ,  420   b , moving the detach mechanism to the second position.  FIG. 12B  shows the delivery system in the second position. It is noted that when the delivery system is in the second position, movement of the actuating mechanism proximally or even further distally may move the gripping elements  420   a ,  420   b  back to the first position. The gripping elements  420   a ,  420   b  may be claws comprising inwardly facing teeth in order to assist in gripping the embolization device. 
     The distal part  434  may be shaped so that it does not fit inside inner lumen  415 . The distal part  434  may comprise a first stopping element, namely a proximal shoulder  417  configured to abut with a corresponding stopping element, namely a distal shoulder  417  of delivery element  410  to form a stopper mechanism so that proximal translation of the actuating mechanism  430  relative to the delivery element  410  past a most proximal position is prevented. This may prevent damage to the gripped medical implant or the detach mechanism  420 . 
       FIG. 13A  shows a delivery system for delivering and deploying an implant to a bodily lumen according to one or more embodiments. The delivery system comprises a delivery element  410  configured to extend through a lumen of a delivery catheter, a detach mechanism  420  mounted to a distal portion of the delivery element  410 , and an actuating mechanism  430 . The delivery element  410 , detach mechanism  420  and actuating mechanism  430  may be made of any suitable material such as a polymer or metal. The detach mechanism  420  has a first configuration in which the detach mechanism  420  is configured to grip the implant, as shown in  FIG. 13A , and a second configuration in which the detach mechanism  420  is configured to release the implant, as shown in  FIG. 13B . The actuating mechanism  430  extends through a lumen of the delivery element  410 . The delivery element  410  prevents the actuating mechanism  420  from buckling. The actuating mechanism  420  is movable between a first position and a second position. The first position is shown in  FIG. 13A . 
     The actuating mechanism  430  of  FIG. 13A  comprises an elongate element  432  (e.g. wire or ribbon) which extends through inner lumen  415  of the delivery element  410 . The detach mechanism  420  comprises a pair of gripping elements  420   a ,  420   b  hingedly mounted to a distal part  434  of the actuating mechanism  430  and connected indirectly to delivery element  410 . Delivery element  410  is hingedly connected to first ends of links  436   a ,  436   b . The gripping elements  420   a ,  420   b  are hingedly connected to second ends of links  436   a ,  436   b  opposite the first ends. Movement of the actuating mechanism  430  distally relative to the delivery element  410  causes the gripping elements  420   a ,  420   b  to be pushed in a distal direction. Further, relative movement of the delivery element in a proximal direction (relative to the actuating mechanism  430 ) causes a pulling force to be exerted on the gripping elements  420   a ,  420   b  via links  436   a ,  436   b . Accordingly, a pivoting force is exerted on the gripping elements  420   a ,  420   b  and the detach mechanism  420  moves to a second position as shown in  FIG. 13B , for releasing a medical implant from the detach mechanism. The delivery element  410  and actuating mechanism  430  may together comprise a stopper mechanism formed by a first stopping element, namely recess  419  on one of the delivery element  419  and actuating mechanism  430  and a second stopping element, namely protrusion  417  on the other. The recess  419  receives the protrusion  417  so that relative displacement of the actuating mechanism beyond a most proximal and a most distal point is prevented. This may prevent damage to the detach mechanism  420  or medical implant when gripped. 
       FIG. 14A  shows a delivery system for delivering and deploying an implant to a bodily lumen according to one or more embodiments. The delivery system comprises a delivery element  410  configured to extend through a lumen of a delivery catheter, a detach mechanism  420  formed integrally as a distal portion of the delivery element  410 , and an actuating mechanism  430 . The delivery element  410 , detach mechanism  420  and actuating mechanism  430  may be made of any suitable material such as a polymer or metal. In particular, in the illustrated embodiment the distal portion of the delivery element  410  comprising the detach mechanism  420  is made of a resiliently deformable material (e.g. resiliently deformable polymer or metal). The detach mechanism  420  is configured to be in the first position, configured to grip a medical implant, in a relaxed configuration. The detach mechanism  420  has a first configuration in which the detach mechanism  420  is configured to grip the implant, as shown in  FIG. 14A , and a second configuration in which the detach mechanism  420  is configured to release the implant, as shown in  FIG. 14B . The actuating mechanism  430  extends through a lumen of the delivery element  410 . The delivery element  410  prevents the actuating mechanism  420  from buckling. The actuating mechanism  420  is movable between a first position and a second position. The first position is shown in  FIG. 14A . 
     The actuating mechanism  420  of  FIG. 14A  comprises a distal part  434 . The distal part  434  comprises one or more ramps  442   a ,  442   b  received by one or more corresponding ramps  440   a ,  440   b  on the distal part of the delivery element  410 . When the actuating mechanism  432  is moved distally relative to the delivery element  410 , the ramps  442  push the actuating mechanism  420  outwards to a second position for releasing the medical implant, as shown in  FIG. 14B . The distal part  434  may comprise a proximal shoulder configured to abut a corresponding shoulder on the delivery element  410 , to form a stopper mechanism to prevent displacement of the actuating mechanism  430  beyond a most proximal position. The gripping elements  420   a ,  420   b  may be claws comprising inwardly facing teeth in order to assist in gripping the embolization device. 
       FIG. 15A  shows a delivery system for delivering and deploying an implant to a bodily lumen according to one or more embodiments. The delivery system comprises a delivery element  410  comprising a plurality of elongate elements configured to extend through a lumen of a delivery catheter, a detach mechanism  420  formed integrally as a distal portion of the elongate elements of delivery element  410 , and an actuating mechanism  430  comprising a sheath  450 . The delivery element  410 , detach mechanism  420  and actuating mechanism  430  may be made of any suitable material such as a polymer or metal. In particular, in the illustrated embodiment the distal portion of the delivery element  410  comprising the detach mechanism  420  is made of a resiliently deformable material (e.g. resiliently deformable polymer or metal). The detach mechanism  420  is configured to be in the second position, configured to release a medical implant, in a relaxed configuration. The detach mechanism  420  has a first configuration in which the detach mechanism  420  is configured to grip the implant, as shown in  FIG. 15A , and a second configuration in which the detach mechanism  420  is configured to release the implant, as shown in  FIG. 15B . The actuating mechanism  420  is movable between a first position and a second position. The first position is shown in  FIG. 15A . The sheath  450  and delivery element  410  may comprise corresponding stopping elements as disclosed in other embodiments. 
     In the first position shown in  FIG. 15A , the sheath  450  prevents the detach mechanism  420  from moving to the relaxed configuration (i.e. the second position for releasing the medical implant). When the sheath  450  is moved proximally relative to the delivery element  410 , the distal part of the delivery element  410  is exposed from the distal end of the sheath  450  and the detach mechanism  420  is free to move to the second position for releasing the medical implant, and shown in  FIG. 15B . 
       FIG. 16A  shows a delivery system for delivering and deploying an implant to a bodily lumen according to one or more embodiments. The delivery system comprises a delivery element  410  configured to extend through a lumen of a delivery catheter, a detach mechanism  420  and an actuating mechanism  430  comprising elongate elements  460   a ,  460   b  (e.g. wires or ribbons). The detach mechanism  430  comprises a pair of gripping elements hingedly mounted to a distal part of the delivery element  410  and has a first configuration in which the detach mechanism  430  is configured to grip the implant, as shown in  FIG. 16A , and a second configuration in which the detach mechanism is configured to release the implant as shown in  FIG. 16B . The elongate elements  460   a ,  460   b  may be received inside one or more lumens of the delivery element  410 . The gripping elements  420   a ,  420   b  may be claws comprising inwardly facing teeth in order to assist in gripping the medical implant. 
     The elongate elements  460   a ,  460   b  are respectively connected to gripping elements  420   a ,  420   b . Translation of the elongate elements  460   a ,  460   b  in a proximal direction relative to the delivery element  410  causes the gripping elements to move from the first position to the second position, as shown in  FIG. 16B . 
     The delivery systems described with respect to  FIGS. 14A-17B  can be used to deploy a medical implant in the manner described with respect to  FIGS. 11A to 11C . 
     The delivery systems disclosed herein may additionally be provided with a delivery catheter configured to fit the delivery system within a lumen of the delivery catheter. 
       FIG. 18  shows a schematic view of an embolization device  110 , which may have any of the features of the embolization device  110  described with respect to  FIG. 1 . The embolization device  110  is connected to a flexible joint  130  which is the same as that described with respect to  FIG. 3A . The flexible joint  130  may be any of the flexible joints described with respect to  FIGS. 3A to 9D . A gripping feature  555  is provided proximal to the flexible joint. The gripping feature  555  is configured to be gripped by a delivery system such as any of those described with reference to  FIGS. 10A to 17B . Accordingly, there may be provided an embolization system comprising an embolization device  110 , the embolization device  110  comprising a self-expandable skeleton and a flow restricting layer mounted on the skeleton, the embolization device  100  having a collapsed delivery configuration in which the embolization device is configured to fit inside a delivery catheter, and an expanded deployed configuration in which the skeleton is configured to anchor the embolization device to a bodily lumen; wherein in the expanded deployed configuration the flow restricting layer extends across the bodily lumen to restrict blood flow through the bodily lumen, wherein the embolization further comprises a detach mechanism for connecting the embolization device to a delivery element and actuatable to release the embolization device from the delivery element; a flexible joint  130  having a higher flexibility than the embolization device  110 , the flexible joint for allowing the embolization device  110  to tilt with respect to the delivery element when the delivery element is connected to the embolization device; a delivery element configured to extend through a lumen of a delivery catheter; a detach mechanism connected to a distal portion of the delivery element, the detach mechanism having a first configuration in which the detach mechanism is configured to grip the embolization device  110  and a second configuration in which the detach mechanism is configured to release the embolization device  110 ; and an actuating mechanism configured to extend through the lumen of the delivery catheter to the detach mechanism, the actuating mechanism movable between a first position and a second position, wherein moving the actuating mechanism from the first position to the second position changes the detach mechanism from the first configuration to the second configuration. Accordingly, any of the embolization systems described with reference to  FIGS. 3A to 9D  in which the flexible joint  130  is provided distally to the detach mechanism  140  may comprise a gripping feature proximal to the flexible joint  130  instead of the screw mechanism or electrolytic element and the delivery element  150  may comprise any detach mechanism configured to grip the gripping element as described in relation to  FIGS. 10A to 17B . 
     All of the above are fully within the scope of the present disclosure, and are considered to form the basis for alternative embodiments in which one or more combinations of the above described features are applied, without limitation to the specific combination disclosed above. 
     In light of this, there will be many alternatives which implement the teaching of the present disclosure. It is expected that one skilled in the art will be able to modify and adapt the above disclosure to suit its own circumstances and requirements within the scope of the present disclosure, while retaining some or all technical effects of the same, either disclosed or derivable from the above, in light of his common general knowledge in this art. All such equivalents, modifications or adaptations fall within the scope of the present disclosure.