Patent Publication Number: US-2006014805-A1

Title: Pesticidal fluoroalkene derivatives

Description:
The present invention relates to pesticidal fluoroalkene derivatives of formula I  
                 
 
 wherein the substituents and the indices have the following meanings: 
      A oxygen or NR a ; 
        R a  hydrogen; C 1 -C 6 -alkyl, C 2 -C 6 -alkenyl, C 2 -C 6 -alkynyl, wherein the carbon atoms may be partially or fully halogenated;    
        X hydrogen, halogen; C 1 -C 6 -alkyl or phenyl wherein the alkyl and phenyl groups may be partially or fully halogenated;     R 1 ,R 2  each independently hydrogen, halogen, hydroxyl, cyano, nitro, mercapto, amino; C 1 -C 6 -alkyl, C 2 -C 6 -alkenyl, C 2 -C 6 -alkynyl, C 1 -C 6 -alkoxy, C 2 -C 6 -alkenyloxy, C 1 -C 6 -alkylthio, C 1 -C 6 -alkylamino, di-C 1 -C 6 -alkylamino, C 1 -C 6 -alkoxycarbonyl, C 1 -C 6 -alkylcarbonyloxy, wherein the aliphatic moieties in these 10 substituents are unsubstituted, partially or fully halogenated or substituted by 1 to 3 substituents, each independently selected from R b : 
        R b  cyano, nitro, halogen, hydroxy, mercapto, amino, carboxyl, aminocarbonyl, aminothiocarbonyl, alkyl, haloalkyl, alkenyl, alkenyloxy, alkynyl, alkoxy, haloalkoxy, alkylthio, alkylamino, dialkylamino, formyl, alkylcarbonyl, alkylsulfonyl, alkoxysulfonyl, alkylsulfonyloxy, alkoxycarbonyl, alkylcarbonyloxy, alkylaminocarbonyl, dialkylaminocarbonyl, alkylaminothiocarbonyl, dialkylaminothiocarbonyl, alkylenedioxy or cycloalkyl, wherein the alkyl groups in these radicals contain 1 to 6 carbon atoms and the abovementioned alkenyl or alkynyl groups in these radicals contain 2 to 6 carbon atoms, and wherein the carbon atoms in these groups may be partially or fully halogenated;    
        Het a monocyclic or bicyclic 3- to 10-membered heteroaromatic ring system containing 1 to 5 heteroatoms selected from oxygen, sulfur and nitrogen, unsubstituted, partially or fully halogenated or substituted by 1 to 4 substituents, each independently selected from R c . 
        R c  R b , C 1 -C 6 -alkoxy-C 1 -C 6 -alkyl, C 6 -alkylsulfinyl, C 1 -C 6 -alkylaminosulfonyl, di-C 1 -C 6 -alkylaminosulfonyl, C 1 -C 6 -alkylcarbonylamino, wherein the last mentioned 5 carbon chains and those defined under R b  are unsubstituted, partially or fully halogenated or substituted by from 1 to 3 cyano, hydroxy, mercapto, amino, C 1 -C 6 -alkylthio, C 1 -C 6 -alkylamino, di-C 1 -C 6 -alkylamino, C 1 -C 6 -alkoxycarbonyl, C 1 -C 6 -alkylcarbonyloxy or nitro groups;     cycloalkyl, cycloalkoxy, saturated or partially unsaturated heterocyclyl, heterocyclyloxy, wherein the cyclic systems contain 3 to 10 ring members, and the carbon atoms in the heterocycles may be substituted by 1 to 4 heteroatoms selected from nitrogen, sulfur and oxygen,     aryl, aryloxy, arylthio, aryl-C 1 -C 6 -alkoxy, aryl-C 1 -C 6 -alkyl, wherein the mono- or bicyclic ring systems contain 5 to 10 ring members,     hetaryl, hetaryloxy, hetarylthio, wherein the mono- or bicyclic ring systems contain 5 to 10 ring members wherein 1 to 3 carbon atoms may be substituted by heteroatoms selected from nitrogen, sulfur and oxygen,     and wherein the cyclic, aromatic and heteroaromatic systems may be partially or fully halogenated or may be substituted by from 1 to 3 groups selected from halogen, cyano, nitro, hydroxy; C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, C 1 -C 6 -alkylthio, C 1 -C 6 -alkylamino, C 1 -C 6 -alkylcarbonyl, C 1 -C 6 -alkoxycarbonyl, di-C 1 -C 6 -alkylamino, C 2 -C 6 -alkenyl, C 2 -C 6 -alkenyloxy and C 2 -C 6 -alkynyl, wherein the carbon atoms of these substituents may be partially or fully halogenated;    
        m 0, 1 or 2;     n 0, 1, 2, or 3;     p 0, 1, 2, 3, 4, 5, or 6.    

      Furthermore, the present invention relates to processes for the preparation of compounds of formula I, compositions containing them and their use for the control of pests such as nematodes, insects, arachnids, harmful fungi and unwanted plants, and the protection of plants from those pests as well as their use for treating, controlling, preventing and protecting warm-blooded animals, fish and humans against infestation and infection by helminths, arachnids and arthropod endo- and ectoparasites.  
      In WO-A 86/07590, nematicidal halosubstituted alkene derivatives are disclosed, some of which are substituted by a carbonyloxy group substituted by dihydrothiazolylthiomethylene.  
      The compounds of formula I differ from the compounds known from WO-A 86/07590 in that they are substituted by aromatic heterocyclic substituents.  
      In WO 97/08130, pesticidal 4,4-difluoro-3-butenylester derivatives and 4,4-difluoro-3-halogen-3-butenylester derivatives are described some of which carry a hetarylthioalkyl substituent on the carbonyl group.  
      Contrary to the compounds disclosed in WO-A 97/08130, in compounds of formula I a hetaryl moiety is bonded to the carbonylalkyl backbone via a sulfur atom.  
      Furthermore, EP-A 1000946 teachers 2-(substituted thio)thiazolo-[4,5-b]pyridine compounds which may bear a haloalkenyl-oxycarbonyl-alkylthio radical as the substituting thio group.  
      However, the pesticidal activity of the compounds known from the above literature in many cases is unsatisfactory.  
      It is an object of the present invention to provide compounds having improved nematicidal, insecticidal and acaricidal activity. It is also an object to provide compounds for controlling harmful fungi, unwanted plants and parasites.  
      We have found that this object is achieved by the fluoroalkene derivatives of formula I. Furthermore, we have found processes for preparing the compounds of formula I and the use of the compounds I and compositions comprising them for use for the control of nematodes, insects, arachnids, harmful fungi and unwanted plants and the protection of plants from those pests as well as for treating, controlling, preventing and protecting warm-blooded animals, fish and humans against infestaion and infection by helminths, acarids and arthropod endo- and ectoparasites.  
      Fluoroalkene derivatives of formula I.1,  
                 
 
 wherein A, X, R 1 , R 2 , Het, n and p are as defined for formula I above, are obtainable by, in a first step, reaction of compounds of formula II
 
Het-SH  (II)
 
 wherein Het is as defined for formula I, with compounds of formula III  
                 
 
 wherein R 1 , R 2  and n are as defined for formula I and L is a nucleophilic exchangeable leaving group, preferably halogen such as bromine, and R i  is hydrogen, C 1 -C 6 -alkyl or aryl-C 1 -C 6 -alkyl, such as benzyl, in the presence of a base to give sulfide compounds of formula IV.  
                 
 
      The reaction to sulfides IV is usually carried out at temperatures of from 0° C. to 150° C., preferably from 15° C. to 80° C., in an inert organic solvent in the presence of a base.  
      Suitable solvents are halogenated hydrocarbons, such as methylene chloride and chlorobenzene, ethers, such as dimethylether, digylme, dioxane and tetrahydrofuran, nitriles, such as acetonitrile, ketones, such as acetone, and also dimethyl sulfoxide, dimethyl formamide and dimethyl acetamide. Preferred solvents are acetone and dimethyl formamide. It is also possible to use mixtures of the solvents mentioned.  
      Suitable bases are, inorganic compounds, such as alkali metal and alkaline earth metal carbonates, such as lithium carbonate, potassium carbonate and calcium carbonate, alkali metal bicarbonates, such as sodium bicarbonate, and also organic bases, such as tertiary amines, such as trimethyl amine, triethyl amine, tri-isopropyl ethyl amine und N-methyl-piperidine, and pyridine. Particular preference is given to alkaline earth metal carbonates, especially potassium carbonate.  
      In general, the base is employed in equimolar amounts or in excess.  
      The starting materials are generally reacted with one another in equimolar amounts. In terms of yield, it may be advantageous to use an excess of compounds of formula III based on compounds Het-SH.  
      Heterocyclic thiols of formula II are known, or are commercially 10 available, or they can be prepared by known methods [see e.g. Synthesis 3, 358-360 (2001)].  
      Compounds of formula IV are known from the literature or are commercially available [see e.g. J. Org. Chem. 62, 9173-9176 (1997)].  
      Compounds of formula IV wherein R i  is C 1 -C 6 -alkyl or aryl-C 1 -C 6 -alkyl are hydrolized to compounds IV wherein R i  is H, for example in the presence of an aqueous acid or base, and reacted with fluoroalkenyl compounds of formula V,  
                 
 
 wherein X and p are as defined for formula I and Y is (a) a nucleophilically exchangeable group, such as halogen or hydroxy, to yield compounds I wherein A is oxygen, or (b) an amino group NHR a , wherein R a  is as defined for formula I, preferably hydrogen, to yield compounds I wherein A is NR a . 
 
      The reaction is carried out by common coupling methods such as in the presence of a base, optionally under activating conditions, such as by converting carboxylic acids of formula V into their corresponding carboxylic acid halides or by means of dehydrating agents such as carbodiimides, to give compounds of formula Ia [lit.: J. March, Advanced Organic Chemistry: reactions, mechanisms and structure, 4th ed. 1992, Wiley &amp; Sons, New York].  
      The reaction is usually carried out at temperatures of from 0° C. to 150° C., preferably from 20° C. to 60° C., in an inert organic solvent in the presence of a base.  
      Suitable solvents are nitriles, such as acetonitrile and propionitrile, and also dimethyl sulfoxide, dimethyl formamide and dimethyl acetamide. Preferred solvents are dimethylether and acetonitrile. It is also possible to use mixtures of the solvents mentioned.  
      The starting materials are generally reacted with one another in equimolar amounts. In terms of yield, it may be advantageous to use an excess of compounds V, based on acids IV.  
      Compounds of formula V are known from the literature or are commercially available [see e.g. WO 86/07590 and WO 95/24403].  
      Sulfinyl and sulfonyl compounds of formula I wherein m is 1 or 2 may be prepared by oxidizing compounds of formula Ia. The oxidation is usually carried out at temperatures of from −10° C. to 150° C., preferably from 0° C. to 60° C., in an inert organic solvent or water. Suitable oxidizing agents are, for example m-chloroperbenzoic acid, peracetic acid, H 2 O 2 ×BF 3 , K 2 S 2 O 7 /H 2 SO 4 , peroxytrifluoroacetic acid, or hydrogen peroxide, optionally in combination with catalytic amounts of sodium tungsten dihydrate.  
      Suitable solvents are halogenated hydrocarbons, such as methylene chloride and chloroform alcohols, such as methanol and tert.-butanol, carboxylic acids such as acetic acid and trifluoroacetic acid, and also dimethyl sulfoxide, dimethyl formamide and dimethyl acetamide. Preferred solvents are methylene chloride and acetic acid. It is also possible to use mixtures of the solvents mentioned.  
      The reaction mixtures are worked up in a customary manner, for example by mixing with water, phase separation and, if appropriate, chromatographic purification of the crude products. In some cases, the intermediates and end products are obtained in the form of colorless or pale brown viscous oils, which are purified or freed from volatile components under reduced pressure and at moderately elevated temperature. If the intermediates and end products are obtained as solids, they can also be purified by recrystallization or digestion.  
      If individual compounds I are not obtainable by the routes described above, they can be prepared by derivatization of other compounds I.  
      In the definitions of the symbols given in the above formulae, collective terms were used which generally represent the following substituents:  
      Halogen: fluorine, chlorine, bromine and iodine;  
      Alkyl: saturated, straight-chain or branched hydrocarbon radicals having 1 to 4 or 6 carbon atoms, such as methyl, ethyl, propyl, 1-methylethyl, butyl, 1-methylpropyl, 2-methylpropyl, 1,1-dimethylethyl, pentyl, 1-methylbutyl, 2-methylbutyl, 3-methylbutyl, 2,2-dimethylpropyl, 1-ethylpropyl, hexyl, 1,1-dimethylpropyl, 1,2-dimethylpropyl, 1-methylpentyl, 2-methylpentyl, 3-methylpentyl, 4-methylpentyl, 1,1-dimethylbutyl, 1,2-dimethylbutyl, 1,3-dimethylbutyl, 2,2-dimethylbutyl, 2,3-dimethylbutyl, 3,3-dimethylbutyl, 1-ethylbutyl, 2-ethylbutyl, 1,1,2-trimethylpropyl, 1,2,2-trimethylpropyl, 1-ethyl-1-methylpropyl and 1-ethyl-2-methylpropyl;  
      Haloalkyl: straight-chain or branched alkyl groups having 1 to 4 or 6 carbon atoms (as mentioned above), where some or all of the hydrogen atoms in these groups may be replaced by halogen atoms as mentioned above, for example C 1 -C 2 -haloalkyl, such as chloromethyl, bromomethyl, dichloromethyl, trichloromethyl, fluoromethyl, difluoromethyl, trifluoromethyl, chlorofluoromethyl, dichlorofluoromethyl, chlorodifluoromethyl, 1-chloroethyl, 1-bromoethyl, 1-fluoroethyl, 2-fluoroethyl, 2,2-difluoroethyl, 2,2,2-trifluoroethyl, 2-chloro-2-fluoroethyl, 2-chloro-2,2-difluoroethyl, 2,2-dichloro-2-fluoroethyl, 2,2,2-trichloroethyl and pentafluoroethyl;  
      Alkenyl: unsaturated, straight-chain or branched hydrocarbon radicals having 2 to 6 carbon atoms and a double bond in any position, such as ethenyl, 1-propenyl, 2-propenyl, 1-methyl-ethenyl, 1-butenyl, 2-butenyl, 3-butenyl, 1-methyl-1-propenyl, 2-methyl-1-propenyl, 1-methyl-2-propenyl, 2-methyl-2-propenyl; 1-pentenyl, 2-pentenyl, 3-pentenyl, 4-pentenyl, 1-methyl-1-butenyl, 2-methyl-1-butenyl, 3-methyl-1-butenyl, 1-methyl-2-butenyl, 2-methyl-2-butenyl, 3-methyl-2-butenyl, 1-methyl-3-butenyl, 2-methyl-3-butenyl, 3-methyl-3-butenyl, 1,1-dimethyl-2-propenyl, 1,2-dimethyl-1-propenyl, 1,2-dimethyl-2-propenyl, 1-ethyl-1-propenyl, 1-ethyl-2-propenyl, 1-hexenyl, 2-hexenyl, 3-hexenyl, 4-hexenyl, 5-hexenyl, 1-methyl-1-pentenyl, 2-methyl-1-pentenyl, 3-methyl-1-pentenyl, 4-methyl-1-pentenyl, 1-methyl-2-pentenyl, 2-methyl-2-pentenyl, 3-methyl-2-pentenyl, 4-methyl-2-pentenyl, 1-methyl-3-pentenyl, 2-methyl-3-pentenyl, 3-methyl-3-pentenyl, 4-methyl-3-pentenyl, 1-methyl-4-pentenyl, 2-methyl-4-pentenyl, 3-methyl-4-pentenyl, 4-methyl-4-pentenyl, 1,1-dimethyl-2-butenyl, 1,1-dimethyl-3-butenyl, 1,2-dimethyl-1-butenyl, 1,2-dimethyl-2-butenyl, 1,2-dimethyl-3-butenyl, 1,3-dimethyl-1-butenyl, 1,3-dimethyl-2-butenyl, 1,3-dimethyl-3-butenyl, 2,2-dimethyl-3-butenyl, 2,3-dimethyl-1-butenyl, 2,3-dimethyl-2-butenyl, 2,3-dimethyl-3-butenyl, 3,3-dimethyl-1-butenyl, 3,3-dimethyl-2-butenyl, 1-ethyl-1-butenyl, 1-ethyl-2-butenyl, 1-ethyl-3-butenyl, 2-ethyl-1-butenyl, 2-ethyl-2-butenyl, 2-ethyl-3-butenyl, 1,1,2-trimethyl-2-propenyl, 1-ethyl-1-methyl-2-propenyl, 1-ethyl-2-methyl-1-propenyl and 1-ethyl-2-methyl-2-propenyl;  
      Haloalkenyl: unsaturated, straight-chain or branched hydrocarbon radicals having 2 to 6 carbon atoms and a double bond in any position (as mentioned above), where some or all of the hydrogen atoms in these groups may be replaced by halogen atoms as mentioned above, in particular by fluorine, chlorine and bromine;  
      Alkynyl: straight-chain or branched hydrocarbon groups having 2 to 6 carbon atoms and a triple bond in any position, such as ethynyl, 1-propynyl, 2-propynyl, 1-butynyl, 2-butynyl, 3-butynyl, 1-methyl-2-propynyl, 1-pentynyl, 2-pentynyl, 3-pentynyl, 4-pentynyl, 1-methyl-2-butynyl, 1-methyl-3-butynyl, 2-methyl-3-butynyl, 3-methyl-1-butynyl, 1,1-dimethyl-2-propynyl, 1-ethyl-2-propynyl, 1-hexynyl, 2-hexynyl, 3-hexynyl, 4-hexynyl, 5-hexynyl, 1-methyl-2-pentynyl, 1-methyl-3-pentynyl, 1-methyl-4-pentynyl, 2-methyl-3-pentynyl, 2-methyl-4-pentynyl, 3-methyl-1-pentynyl, 3-methyl-4-pentynyl, 4-methyl-1-pentynyl, 4-methyl-2-pentynyl, 1,1-dimethyl-2-butynyl, 1,1-dimethyl-3-butynyl, 1,2-dimethyl-3-butynyl, 2,2-dimethyl-3-butynyl, 3,3-dimethyl-1-butynyl, 1-ethyl-2-butynyl, 1-ethyl-3-butynyl, 2-ethyl-3-butynyl and 1-ethyl-1-methyl-2-propynyl;  
      Haloalkynyl: straight-chain or branched hydrocarbon groups having 2 to 6 carbon atoms and a triple bond in any position (as mentioned above), where some or all of the hydrogen atoms in these groups may be replaced by halogen atoms as mentioned above, in particular by fluorine, chlorine and bromine;  
      Alkoxycarbonyl: straight-chain or branched alkoxy groups having 1 to 6 carbon atoms (as mentioned above) which are attached to the skeleton via a carbonyl group (—CO—); Alkylaminocarbonyl: straight-chain or branched alkylamino groups having 1 to 6 carbon atoms (as mentioned above) which are attached to the skeleton via a carbonyl group (—CO—);  
      Alkylcarbonyloxy: straight-chain or branched alkyl groups having 1 to 6 carbon atoms (as mentioned above) which are attached to the skeleton via a carbonyloxy group (—C(═O)O—);  
      Cycloalkyl: monocyclic or bicyclic saturated hydrocarbon groups having 3 to 6, 8 or 10 carbon ring atoms, e.g. C 3 -C 8 -cycloalkyl such as cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, cycloheptyl, cyclooctyl and dihydronaphthalin;  
      Heterocyclyl: 5- to 10-membered saturated or partially unsaturated rings which besides carbon ring atoms contain from 1 to 3 or 4 heteroatoms selected from nitrogen, oxygen and sulfur, e.g. from 1 to 3 nitrogen atoms and/or 1 oxygen or sulfur atom and/or 1 or 2 oxygen and/or sulfur atoms;  
      Aryl: mono- or bicyclic aromatic ringsystems containing 5 to 10 carbon ring atoms, e.g. phenyl or naphthyl;  
      Arylmethylene: mono- or bicyclic aromatic ringsystems containing 5 to 14 carbon ring atoms (as mentioned above) which are attached to the skeleton via a methylene (—CH 2 —) group.  
      Hetaryl: a monocyclic or bicyclic 3- to 10-membered heteroaromatic ring system containing 1 to 5 heteroatoms selected from oxygen, sulfur and nitrogen,  
      e.g. 5-membered hetaryl containing beside carbon atoms 1 to 3 nitrogen atoms and/or 1 sulfur- or oxygen atom, wherein the ring system may be bonded to the backbone via carbon or nitrogen, such as furyl, thienyl, pyrrolyl, isoxazolyl, isothiazolyl, pyrazolyl, oxazolyl, thiazolyl, imidazolyl, 1,2,4-oxadiazolyl, 1,2,4-thiadiazolyl, 1,2,4-triazolyl, 1,3,4-oxadiazolyl, 1,3,4-thiadiazolyl and 1,3,4-triazolyl; or e.g. 5-membered hetaryl containing beside carbon atoms 1 to 3 nitrogen atoms and/or 1 sulfur- or oxygen atom, wherein the ring system may be bonded to the backbone via carbon or nitrogen, wherein 2 adjacent ring members are bridged by a buta-1,3-dien-1,4-diyl group, wherein 1 or 2 carbon atoms may be substituted by nitrogen atoms, such as benzofuranyl, isobenzofuranyl, benzothienyl, isobenzothienyl, indolyl, isoindolyl, indazolyl, indoleninyl, isobenzazolyl, pyranopyrrolyl, isoindazolyl, indoxazinyl, benzoxazolyl, benzothiazolyl, benzimidazolyl, pyridoxazolyl, pyridothiazolyl, pyrazinoxazolyl, pyrazinthiazolyl, pyridazinoxazolyl, pyridazinthiazolyl, pyrimidinoxazolyl, pyrimidinthiazolyl, pyrimidinazolyl, benzopyranyl, purinyl;  
      Alkylsulfinyl: straight-chain or branched alkyl groups having 1 to 6 carbon atoms (as mentioned above) which are attached to the skeleton via a sulfinyl group (—SO—);  
      Alkylsulfonyl: straight-chain or branched alkyl groups having 1 to 6 carbon atoms (as mentioned above) which are attached to the skeleton via a sulfonyl group (—SO 2 —);  
      Alkylsulfonyloxy: straight-chain or branched alkylsulfonyl groups having 1 to 6 carbon atoms (as mentioned above) which are attached to the skeleton via an oxygen atom;  
      Alkoxysulfonyl: straight-chain or branched alkoxy groups having 1 to 6 carbon atoms (as mentioned above) which are attached to the skeleton via a sulfonyl group (—SO 2 —);  
      Alkylaminosulfonyl: straight-chain or branched alkylamino groups having 1 to 6 carbon atoms (as mentioned above) which are attached to the skeleton via a sulfonyl group (—SO 2 —);  
      With respect to the intended use of the fluoroalkene derivatives of formula I, particular preference is given to the following meanings of the substituents, in each case on their own or in combination:  
      Preference is given to compounds of formula I wherein A is oxygen or NH.  
      Particular preference is given to compounds of formula I wherein A is oxygen.  
      Preference is given to compounds of the formula I in which R a  is hydrogen or C 1 -C 6 -alkyl, hydrogen being preferred most.  
      Furthermore, preference is given to compounds of formula I wherein X is hydrogen, halogen, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, or phenyl.  
      Particular preference is given to compounds of formula I wherein X is hydrogen or halogen, especially fluorine.  
      Especially preferred are compounds of formula I wherein X is fluorine.  
      Preference is given to compounds of formula I wherein R 1  and R 2  are each independently hydrogen, halogen, C 1 -C 6 -alkyl, or phenyl wherein the alkyl and phenyl group are unsubstituted, partially or fully halogenated.  
      Particular preference is given to compounds of formula I wherein R 1  and R 2  are each independently hydrogen, halogen, C 1 -C 4 -alkyl, or phenyl.  
      Especially preferred are compounds of formula I wherein R 1  and R 2  are each independently hydrogen or C 1 -C 4 -alkyl.  
      Particular preference is given to compounds of formula I wherein one of R 1  and R 2  is not hydrogen.  
      Particular preference is given to compounds of the formula I wherein R b  is halogen, hydroxy, C 1 -C 6 -alkyl, C 1 -C 6 -haloalkyl, C 1 -C 6 -alkoxy or C 1 -C 6 -haloalkoxy.  
      Especially preferred are compounds of the formula I wherein R 1  and R 2  are substituted by hydrogen or C 1 -C 6 -alkyl, hydrogen being preferred most.  
      Preference is given to compounds of the formula I wherein Het is bonded via carbon.  
      Particular preference is given to compounds of the formula I wherein Het is oxazolyl, thiazolyl, imidazolyl, pyrimidinyl, pyridyl, purinyl, pyridazinonyl, benzoxazolyl, pyridoxazolyl, benzothiazolyl, pyridothiazolyl, benzimidazolyl, pyrimidinazolyl, 1,3,4-oxadiazol-2-yl, or 1,3,4-thiadiazol-2-yl, each ring system being unsubstituted, partially or fully halogenated or substituted by from 1 to 3 or 4 groups selected from R c  as defined for formula I above.  
      Particular preference is given to compounds of the formula I wherein Het is 2-oxazolyl, 2-thiazolyl, 2-imidazolyl, 2-pyrimidinyl, 2-pyridyl, 2-purinyl, 5-pyridazinonyl, 2-benzoxazolyl, 2-pyridoxazolyl, 2-benzothiazolyl, 2-benzimidazolyl, 2-pyrimidinazolyl, 1,3,4-oxadiazol-2-yl, or 1,3,4-thiadiazol-2-yl, each ring system being unsubstituted, partially or fully halogenated or substituted by from 1 to 3 or 4 groups selected from R c  as defined for formula I above.  
      Especially preferred are compounds of formula I wherein Het is 2-oxazolyl, 2-thiazolyl, 2-benzoxazolyl, 2-pyridoxazolyl, 2-benzothiazolyl, 1,3,4-oxadiazol-2-yl, or 1,3,4-thiadiazol-2-yl, each ring system being unsubstituted, partially or fully halogenated or substituted by from 1 to 2 or 3 groups selected from R c  as defined for formula I above.  
      Preference is given to compounds of the formula I wherein R c  is cyano, nitro, halogen, hydroxy, mercapto, amino, carboxyl, aminocarbonyl, alkyl, haloalkyl, alkoxyalky, alkenyl, alkenyloxy, alkynyl, alkoxy, haloalkoxy, alkylthio, alkylamino, dialkylamino, formyl, alkylcarbonyl, alkylsulfonyl, alkoxycarbonyl, alkylcarbonyloxy, alkylaminocarbonyl, or dialkylaminocarbonyl, wherein the alkyl groups in these radicals contain 1 to 6 carbon atoms and the abovementioned alkenyl or alkynyl groups in these radicals contain 2 to 6 carbon atoms, and wherein the carbon atoms in these groups may be partially or fully halogenated, or 5- to 10-membered mono- or bicyclic aryl, or 5- to 10-membered mono-or bicyclic hetaryl, wherein 1 to 3 carbon atoms may be substituted by heteroatoms selected from nitrogen, sulfur and oxygen, wherein the aryl or hetaryl ring systems may be partially or fully halogenated or may be substituted by from 1 to 3 groups selected from halogen, cyano, nitro, hydroxy, C 1 -C 6 -alkyl, C 1 -C 6 -haloalkyl, C 1 -C 6 -alkoxy, or C 1 -C 6 -haloalkoxy.  
      Particular preference is given to compounds of the formula I wherein R c  is hydroxy, halogen, C 1 -C 6 -alkyl, C 1 -C 6 -haloalkyl, C 1 -C 6 -alkoxy, C 1 -C 6 -haloalkoxy and phenyl, unsubstituted, partially or fully halogenated or substituted by from 1 to 3 nitro, hydroxy, cyano, C 1 -C 6 -alkyl, C 1 -C 6 -haloalkyl, C 1 -C 6 -alkoxy, C 1 -C 6 -haloalkoxy, C 1 -C 6 -alkylamino, or di-C 1 -C 6 -alkylamino.  
      Particular preference is given to compounds of the formula I in which m is 0 or 2.  
      Particular preference is given to compounds of the formula I in which m is zero.  
      Preference is given to compounds of the formula I in which n is 0 or 1.  
      Particular preference is given to compounds of the formula I in which n is zero.  
      Preference is given to compounds of the formula I in which p is 2 or 4.  
      Preference is given to compounds of the formula I in which p is 2.  
      Moreover, fluoroalkene derivatives of formula I are preferred wherein the substituents and the indices have the following meanings: 
      A oxygen or NH;     X hydrogen or halogen;     R 1 ,R 2  each independently hydrogen, C 1 -C 6 -alkyl, or phenyl which is unsubstituted or substituted by one to three halogen atoms;     Het oxazolyl, thiazolyl, imidazolyl, pyrimidinyl, pyridyl, purinyl, pyridazinonyl, benzoxazolyl, pyridoxazolyl, benzothiazolyl, pyridothiazolyl, benzimidazolyl, pyrimidazolyl, oxadiazolyl, or thiadiazolyl, each ring being unsubstituted, partially or fully halogenated or substituted by from one to three groups selected from R c . 
        R c  is hydroxy, halogen, C 1 -C 6 -alkyl, C 1 -C 6 -haloalkyl, C 1 -C 6 -alkoxy, C 1 -C 6 -haloalkoxy and phenyl, unsubstituted, partially or fully halogenated or substituted by from 1 to 3 nitro, hydroxy, cyano, C 1 -C 6 -alkyl, C 1 -C 6 -haloalkyl, C 1 -C 6 -alkoxy, C 1 -C 6 -haloalkoxy, C 1 -C 6 -alkylamino, or di-C 1 -C 6 -alkylamino.    
        m,n 0, 1 or 2;     p 2 or 4;    

      Likewise, particular preference is given to compounds of the formula I wherein substituents and the indices have the following meanings: 
      A oxygen;     X hydrogen or fluorine;     R 1 , R 2  each independently hydrogen, C 1 -C 4 -alkyl; Het 2-oxazolyl, 2-thiazolyl, 2-benzoxazolyl, 2-pyridoxazolyl, 2-benzothiazolyl, 2-pyridothiazolyl, 1,3,4-oxadiazol-2-yl, or 1,3,4-thiadiazol-2-yl, each ring being unsubstituted, partially or fully halogenated or substituted by from one to three groups selected from hydroxy, C 1 -C 6 -alkyl, C 1 -C 6 -haloalkyl, C 1 -C 6 -alkoxy, C 1 -C 6 -haloalkoxy, or phenyl, unsubstituted, partially or fully halogenated or substituted by from 1 to 3 nitro, cyano, C 1 -C 6 -alkyl, C 1 -C 6 -haloalkyl, C 1 -C 6 -alkoxy or C 1 -C 6 -haloalkoxy groups.     m,n zero;     p 2 or 4.    

      Particular preference is given to compounds of formula I wherein A is oxygen, X is hydrogen or fluorine, R 1  and R 2  are each independently hydrogen, C 1 -C 4 -alkyl, or phenyl, Het is 2-benzoxazolyl, 2-benzothiazolyl, 4-pyridothiazol-2-yl, 4-pyridoxazol-2-yl, 5-pyridothiazol-2-yl, 5-pyridoxazol-2-yl, 6-pyridothiazol-2yl, 6-pyridoxazol-2-yl, 7-pyridothiazol-2-yl, 7-pyridoxazol-2-yl, 2-pyrazinthiazolyl, 2-pyrazinoxazolyl, each ring being unsubstituted or substituted by 1 group selected from halogen, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 4 -haloalkoxy, C 1 -C 4 -alkoxy, nitro, amino, and methylcarbonylamino, m is zero, n is 1, and p is 2 or 4.  
      Particular preference is given to compounds of formula I wherein A is oxygen, X is hydrogen or fluorine, R 1  and R 2  are each independently hydrogen, C 1 -C 4 -alkyl, or phenyl, Het is 2-oxazolyl, 2-thiazolyl, 2-imidazolyl, each ring being unsubstituted or substituted by 1 or 2 groups selected from halogen, C 1 -C 4 -alkyl, C 1 -C 4 -alkoxymethylene, C 1 -C 4 -alkylcarbonyloxy, and phenyl which may be substutited by from 1 to 3 substituents selected from halogen, C 1 -C 4 -alkyl and hydroxy, m is zero, n is 1, and p is 2 or 4.  
      Particular preference is given to compounds of formula I wherein A is oxygen, X is hydrogen or fluorine, R 1  and R 2  are each independently hydrogen, C 1 -C 4 -alkyl, or phenyl, Het is thiadiazolyl or oxadiazolyl, each ring being unsubstituted or substituted by one group selected from halogen, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 4 -haloalkoxy, C 1 -C 4 -alkoxy, nitro, amino, and methylcarbonylamino, m and n are integers of 0, and p is an integer of 2 or 4.  
      Furthermore, compounds of the following formulae are especially preferred:  
      Compounds of formula I.2  
                 
 
 wherein B is nitrogen or CH, in particular CH, D is nitrogen or CH, in particular CH, E is oxygen or sulfur, R 1  and R 2  are each independently hydrogen, C 1 -C 4 -alkyl or phenyl, q is 0 or 1, R c  is halogen, methyl, methoxy, ethoxy, trifluoromethyl, trifluoromethoxy, m is 0, 1 or 2, n is 0 or 1 and p is 2 or 4, with the proviso that B is CH when E is sulfur. 
 
      Compounds of formula I.3  
                 
 
 wherein E′ is oxygen, sulfur or NH, R 1  and R 2  are each independently hydrogen or C 1 -C 4 -alkyl, q is 0, 1 , or 2, R c  is phenyl which may be substituted by one or two halogen, m is 0, 1 or 2, n is 0 or 1, p is 2 or 4. 
 
      Compounds of formula I.4  
                 
 
 wherein E is oxygen or sulfur, R 1  and R 2  are each independently hydrogen or C 1 -C 4 -alkyl, R c  is C 1 -C 4 -alkyl or phenyl which may be substituted by halogen or methyl, and p is 2. 
 
      With respect to their use, particular preference is given to the compounds I.5, I.6 and I.7 compiled in the Tables below. Moreover, the groups mentioned for a substituent in the Tables are on their own, independently of the combination in which they are mentioned, a particularly preferred embodiment of the substituent in question.  
      Further preference is given to the compounds of the tables 1 to 440 wherein A is NH.  
      Table 1  
      Compounds of the formula I.5  
                 
 
 wherein X is hydrogen, p is 2, R 1  and R 2  are hydrogen and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A. 
 
      Table 2  
      Compounds of the formula I.5 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is methyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 3  
      Compounds of the formula I.5 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is ethyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 4  
      Compounds of the formula I.5 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is i-propyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 5  
      Compounds of the formula I.5 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-propyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 6  
      Compounds of the formula I.5 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 7  
      Compounds of the formula I.5 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-butyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 8  
      Compounds of the formula I.5 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is i-butyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 9  
      Compounds of the formula I.5 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is tert-butyl and the combination of B, D, E and R b  for a compound corresponds in each case to a row of Table A.  
      Table 10  
      Compounds of the formula I.5 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is phenyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 11  
      Compounds of the formula I.5 wherein X is hydrogen, p is 4, R 1  and R 2  are hydrogen and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 12  
      Compounds of the formula I.5 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is methyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 13  
      Compounds of the formula I.5 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is ethyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 14  
      Compounds of the formula I.5 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-propyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 15  
      Compounds of the formula I.5 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-propyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 16  
      Compounds of the formula I.5 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 17  
      Compounds of the formula I.5 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-butyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 18  
      Compounds of the formula I.5 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-butyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 19  
      Compounds of the formula I.5 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is tert-butyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 20  
      Compounds of the formula I.5 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is phenyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 21  
      Compounds of the formula I.5 wherein X is fluorine, p is 2, R 1  and R 2  are hydrogen and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 22  
      Compounds of the formula I.5 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is methyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 23  
      Compounds of the formula I.5 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is ethyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 24  
      Compounds of the formula I.5 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-propyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 25  
      Compounds of the formula I.5 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-propyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 26  
      Compounds of the formula I.5 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 27  
      Compounds of the formula I.5 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-butyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 28  
      Compounds of the formula I.5 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-butyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 29  
      Compounds of the formula I.5 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is tert-butyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 30  
      Compounds of the formula I.5 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is phenyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 31  
      Compounds of the formula I.5 wherein X is fluorine, p is 4, R 1  and R 2  are hydrogen and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 32  
      Compounds of the formula I.5 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is methyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 33  
      Compounds of the formula I.5 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is ethyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 34  
      Compounds of the formula I.5 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-propyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 35  
      Compounds of the formula I.5 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-propyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 36  
      Compounds of the formula I.5 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 37  
      Compounds of the formula I.5 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-butyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 38  
      Compounds of the formula I.5 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-butyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 39  
      Compounds of the formula I.5 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is tert-butyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
      Table 40  
      Compounds of the formula I.5 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is phenyl and the combination of B, D, E and R c  for a compound corresponds in each case to a row of Table A.  
                   TABLE A                              (I.5)                                                                           Nr.   B   D   E   R c                         A-1   CH   CH   O   —           A-2   CH   CH   O   4-CH 3             A-3   CH   CH   O   4-CH 2 CH 3             A-4   CH   CH   O   4-CH 2 CH 2 CH 3             A-5   CH   CH   O   4-CH(CH 3 ) 2             A-6   CH   CH   O   4-CH 2 CH 2 CH 2 CH 3             A-7   CH   CH   O   4-CH 2 CH(CH 3 ) 2             A-8   CH   CH   O   4-CH(CH 3 ) 3             A-9   CH   CH   O   4-F           A-10   CH   CH   O   4-Cl           A-11   CH   CH   O   4-Br           A-12   CH   CH   O   4-I           A-13   CH   CH   O   4-CF 3             A-14   CH   CH   O   4-OCF 3             A-15   CH   CH   O   4-OCH 3             A-16   CH   CH   O   4-OCH 2 CH 3             A-17   CH   CH   O   4-OCH 2 CH 2 CH 3             A-15   CH   CH   O   4-OCH(CH 3 ) 2             A-19   CH   CH   O   4-NO 2             A-20   CH   CH   O   4-NH 2             A-21   CH   CH   O   4-NH(C}O)CH 3             A-22   CH   CH   O   5-CH 3             A-23   CH   CH   O   5-CH 2 CH 3             A-24   CH   CH   O   5-CH 2 CH 2 CH 3             A-25   CH   CH   O   5-CH(CH 3 ) 2             A-26   CH   CH   O   5-CH 2 CH 2 CH 2 CH 3             A-27   CH   CH   O   5-CH 2 CH(CH 3 ) 2             A-28   CH   CH   O   5-CH(CH 3 ) 3             A-29   CH   CH   O   5-F           A-30   CH   CH   O   5-Cl           A-31   CH   CH   O   5-Br           A-32   CH   CH   O   5-I           A-33   CH   CH   O   5-CF 3             A-34   CH   CH   O   5-OCF 3             A-35   CH   CH   O   5-OCH 3             A-36   CH   CH   O   5-OCH 2 CH 3             A-37   CH   CH   O   5-OCH 2 CH 2 CH 3             A-38   CH   CH   O   5-OCH(CH 3 ) 2             A-39   CH   CH   O   5-NO 2             A-40   CH   CH   O   5-NH 2             A-41   CH   CH   O   5-NH(C}O)CH 3             A-42   CH   CH   O   6-CH 3             A-43   CH   CH   O   6-CH 2 CH 3             A-44   CH   CH   O   6-CH 2 CH 2 CH 3             A-45   CH   CH   O   6-CH(CH 3 ) 2             A-46   CH   CH   O   6-CH 2 CH 2 CH 2 CH 3             A-47   CH   CH   O   6-CH 2 CH(CH 3 ) 2             A-48   CH   CH   O   6-CH(CH 3 ) 3             A-49   CH   CH   O   6-F           A-50   CH   CH   O   6-Cl           A-51   CH   CH   O   6-Br           A-52   CH   CH   O   6-I           A-53   CH   CH   O   6-CF 3             A-54   CH   CH   O   6-OCF 3             A-55   CH   CH   O   6-OCH 3             A-56   CH   CH   O   6-OCH 2 CH 3             A-57   CH   CH   O   6-OCH 2 CH 2 CH 3             A-58   CH   CH   O   6-OCH(CH 3 ) 2             A-59   CH   CH   O   6-NO 2             A-60   CH   CH   O   6-NH 2             A-61   CH   CH   O   6-NH(C}O)CH 3             A-62   CH   CH   O   7-CH 3             A-63   CH   CH   O   7-CH 2 CH 3             A-64   CH   CH   O   7-CH 2 CH 2 CH 3             A-65   CH   CH   O   7-CH(CH 3 ) 2             A-66   CH   CH   O   7-CH 2 CH 2 CH 2 CH 3             A-67   CH   CH   O   7-CH 2 CH(CH 3 ) 2             A-68   CH   CH   O   7-CH(CH 3 ) 3             A-69   CH   CH   O   7-F           A-70   CH   CH   O   7-Cl           A-71   CH   CH   O   7-Br           A-72   CH   CH   O   7-I           A-73   CH   CH   O   7-CF 3             A-74   CH   CH   O   7-OCF 3             A-75   CH   CH   O   7-OCH 3             A-76   CH   CH   O   7-OCH 2 CH 3             A-77   CH   CH   O   7-OCH 2 CH 2 CH 3             A-78   CH   CH   O   7-OCH(CH 3 ) 2             A-79   CH   CH   O   7-NO 2             A-80   CH   CH   O   7-NH 2             A-81   CH   CH   O   7-NH(C}O)CH 3             A-82   CH   CH   S   —           A-83   CH   CH   S   4-CH 3             A-84   CH   CH   S   4-CH 2 CH 3             A-85   CH   CH   S   4-CH 2 CH 2 CH 3             A-86   CH   CH   S   4-CH(CH 3 ) 2             A-87   CH   CH   S   4-CH 2 CH 2 CH 2 CH 3             A-88   CH   CH   S   4-CH 2 CH(CH 3 ) 2             A-89   CH   CH   S   4-CH(CH 3 ) 3             A-90   CH   CH   S   4-F           A-91   CH   CH   S   4-Cl           A-92   CH   CH   S   4-Br           A-93   CH   CH   S   4-I           A-94   CH   CH   S   4-CF 3             A-95   CH   CH   S   4-OCF 3             A-96   CH   CH   S   4-OCH 3             A-97   CH   CH   S   4-OCH 2 CH 3             A-98   CH   CH   S   4-OCH 2 CH 2 CH 3             A-99   CH   CH   S   4-OCH(CH 3 ) 2             A-100   CH   CH   S   4-NO 2             A-101   CH   CH   S   4-NH 2             A-102   CH   CH   S   4-NH(C}O)CH 3             A-103   CH   CH   S   5-CH 3             A-104   CH   CH   S   5-CH 2 CH 3             A-105   CH   CH   S   5-CH 2 CH 2 CH 3             A-106   CH   CH   S   5-CH(CH 3 ) 2             A-107   CH   CH   S   5-CH 2 CH 2 CH 2 CH 3             A-108   CH   CH   S   5-CH 2 CH(CH 3 ) 2             A-109   CH   CH   S   5-CH(CH 3)   3             A-110   CH   CH   S   5-F           A-111   CH   CH   S   5-Cl           A-112   CH   CH   S   5-Br           A-113   CH   CH   S   5-I           A-114   CH   CH   S   5-CF 3             A-115   CH   CH   S   5-OCF 3             A-116   CH   CH   S   5-OCH 3             A-117   CH   CH   S   5-OCH 2 CH 3             A-118   CH   CH   S   5-OCH 2 CH 2 CH 3             A-119   CH   CH   S   5-OCH(CH 3 ) 2             A-120   CH   CH   S   5-NO 2             A-121   CH   CH   S   5-NH 2             A-122   CH   CH   S   5-NH(C}O)CH 3             A-123   CH   CH   S   6-CH 3             A-124   CH   CH   S   6-CH 2 CH 3             A-125   CH   CH   S   6-CH 2 CH 2 CH 3             A-126   CH   CH   S   6-CH(CH 3 ) 2             A-127   CH   CH   S   6-CH 2 CH 2 CH 2 CH 3             A-128   CH   CH   S   6-CH 2 CH(CH 3 ) 2             A-129   CH   CH   S   6-CH(CH 3 ) 3             A-130   CH   CH   S   6-F           A-131   CH   CH   S   6-Cl           A-132   CH   CH   S   6-Br           A-133   CH   CH   S   6-I           A-134   CH   CH   S   6-CF 3             A-135   CH   CH   S   6-OCF 3             A-136   CH   CH   S   6-OCH 3             A-137   CH   CH   S   6-OCH 2 CH 3             A-138   CH   CH   S   6-OCH 2 CH 2 CH 3             A-139   CH   CH   5,,   6-OCH(CH 3 ) 2             A-140   CH   CH   S   6-NO 2             A-141   CH   CH   S   6-NH 2             A-142   CH   CH   S   6-NH(C}O)CH 3             A-143   CH   CH   S   7-CH 3             A-144   CH   CH   S   7-CH 2 CH 3             A-145   CH   CH   S   7-CH 2 CH 2 CH 3             A-146   CH   CH   S   7-CH(CH 3 ) 2             A-147   CH   CH   S   7-CH 2 CH 2 CH 2 CH 3             A-148   CH   CH   S   7-CH 2 CH(CH 3 ) 2             A-149   CH   CH   S   7-CH(CH 3 ) 3             A-150   CH   CH   S   7-F           A-151   CH   CH   S   7-Cl           A-152   CH   CH   S   7-Br           A-153   CH   0H   S   7-I           A-154   CH   CH   S   7-CF 3             A-155   CH   CH   S   7-OCF 3             A-156   CH   CH   S   7-OCH 3             A-157   CH   CH   S   7-OCH 2 CH 3             A-158   CH   CH   S   7-OCH 2 CH 2 CH 3             A-159   CH   CH   S   7-OCH(CH 3 ) 2             A-160   CH   CH   S   7-NO 2             A-161   CH   CH   S   7-NH 2             A-162   CH   CH   S   7-NH(C}O)CH 3             A-163   CH   N   O   —           A-164   CH   N   O   4-CH 3             A-165   CH   N   O   4-CH 2 CH 3             A-166   CH   N   O   4-CH 2 CH 2 CH 3             A-167   CH   N   O   4-CH(CH 3 ) 2             A-168   CH   N   O   4-CH 2 CH 2 CH 2 CH 3             A-169   CH   N   O   4-CH 2 CH(CH 3 ) 2             A-170   CH   N   O   4-CH(CH 3 ) 3             A-171   CH   N   O   4-F           A-172   CH   N   O   4-Cl           A-173   CH   N   O   4-Br           A-174   CH   N   O   4-I           A-175   CH   N   O   4-CF 3             A-176   CH   N   O   4-OCF 3             A-177   CH   N   O   4-OCH 3             A-178   CH   N   O   4-OCH 2 CH 3             A-179   CH   N   O   4-OCH 2 CH 2 CH 3             A-180   CH   N   O   4-OCH(CH 3 ) 2             A-181   CH   N   O   4-NO 2             A-182   CH   N   O   4-NH 2             A-183   CH   N   O   4-NH(C}O)CH 3             A-184   CH   N   O   5-CH 3             A-185   CH   N   O   5-CH 2 CH 3             A-186   CH   N   O   5-CH 2 CH 2 CH 3             A-187   CH   N   O   5-CH(CH 3 ) 2             A-188   CH   N   O   5-CH 2 CH 2 CH 2 CH 3             A-189   CH   N   O   5-CH 2 CH(CH 3 ) 2             A-190   CH   N   O   5-CH(CH 3 ) 3             A-191   CH   N   O   5-F           A-192   CH   N   O   5-Cl           A-193   CH   N   O   5-Br           A-194   CH   N   O   5-I           A-195   CH   N   O   5-CF 3             A-196   CH   N   O   5-OCF 3             A-197   CH   N   O   5-OCH 3             A-198   CH   N   O   5-OCH 2 CH 3             A-199   CH   N   O   5-OCH 2 CH 2 CH 3             A-200   CH   N   O   5-OCH(CH 3 ) 2             A-201   CH   N   O   5-NO 2             A-202   CH   N   O   5-NH 2             A-203   CH   N   O   5-NH(C}O)CH 3             A-204   CH   N   O   6-CH 3             A-205   CH   N   O   6-CH 2 CH 3             A-206   CH   N   O   6-CH 2 CH 2 CH 3             A-207   CH   N   O   6-CH(CH 3 ) 2             A-208   CH   N   O   6-CH 2 CH 2 CH 2 CH 3             A-209   CH   N   O   6-CH 2 CH(CH 3 ) 2             A-210   CH   N   O   6-CH(CH 3)   3             A-211   CH   N   O   6-F           A-212   CH   N   O   6-Cl           A-213   CH   N   O   6-Br           A-214   CH   N   O   6-I           A-215   CH   N   O   6-CF 3             A-216   CH   N   O   6-OCF 3             A-217   CH   N   O   6-OCH 3             A-218   CH   N   O   6-OCH 2 CH 3             A-219   CH   N   O   6-OCH 2 CH 2 CH 3             A-220   CH   N   O   6-OCH(CH 3 ) 2             A-221   CH   N   O   6-NO 2             A-222   CH   N   O   6-NH 2             A-223   CH   N   O   6-NH(C}O)CH 3             A-224   CH   N   S   —           A-225   CH   N   S   4-CH 3             A-226   CH   N   S   4-CH 2 CH 3             A-227   CH   N   S   4-CH 2 CH 2 CH 3             A-228   CH   N   S   4-CH(CH 3 ) 2             A-229   CH   N   S   4-CH 2 CH 2 CH 2 CH 3             A-230   CH   N   S   4-CH 2 CH(CH 3 ) 2             A-231   CH   N   S   4-CH(CH 3 ) 3             A-232   CH   N   S   4-F           A-233   CH   N   S   4-Cl           A-234   CH   N   S   4-Br           A-235   CH   N   S   4-I           A-236   CH   N   S   4-CF 3             A-237   CH   N   S   4-OCF 3             A-238   CH   N   S   4-OCH 3             A-239   CH   N   S   4-OCH 2 CH 3             A-240   CH   N   S   4-OCH 2 CH 2 CH 3             A-241   CH   N   S   4-OCH(CH 3 ) 2             A-242   CH   N   S   4-NO 2             A-243   CH   N   S   4-NH 2             A-244   CH   N   S   4-NH(C}O)CH 3             A-245   CH   N   S   5-CH 3             A-246   CH   N   S   5-CH 2 CH 3             A-247   CH   N   S   5-CH 2 CH 2 CH 3             A-248   CH   N   S   5-CH(CH 3 ) 2             A-249   CH   N   S   5-CH 2 CH 2 CH 2 CH 3             A-250   CH   N   S   5-CH 2 CH(CH 3 ) 2             A-251   CH   N   S   5-CH(CH 3 ) 3             A-252   CH   N   S   5-F           A-253   CH   N   S   5-Cl           A-254   CH   N   S   5-Br           A-255   CH   N   S   5-I           A-256   CH   N   S   5-CF 3             A-257   CH   N   S   5-OCF 3             A-258   CH   N   S   5-OCH 3             A-259   CH   N   S   5-OCH 2 CH 3             A-260   CH   N   S   5-OCH 2 CH 2 CH 3             A-261   CH   N   S   5-OCH(CH 3 ) 2             A-262   CH   N   S   5-NO 2             A-263   CH   N   S   5-NH 2             A-264   CH   N   S   5-NH(C}O)CH 3             A-265   CH   N   S   6-CH 3             A-266   CH   N   S   6-CH 2 CH 3             A-267   CH   N   S   6-CH 2 CH 2 CH 3             A-268   CH   N   S   6-CH(CH 3 ) 2             A-269   CH   N   S   6-CH 2 CH 2 CH 2 CH 3             A-270   CH   N   S   6-CH 2 CH(CH 3 ) 2             A-271   CH   N   S   6-CH(CH 3 ) 3             A-272   CH   N   S   6-F           A-273   CH   N   S   6-Cl           A-274   CH   N   S   6-Br           A-275   CH   N   S   6-I           A-276   CH   N   S   6-CF 3             A-277   CH   N   S   6-OCF 3             A-278   CH   N   S   6-OCH 3             A-279   CH   N   S   6-OCH 2 CH 3             A-280   CH   N   S   6-OCH 2 CH 2 CH 3             A-281   CH   N   S   6-OCH(CH 3 ) 2             A-282   CH   N   S   6-NO 2             A-283   CH   N   S   6-NH 2             A-284   CH   N   S   6-NH(C}O)CH 3             A-285   N   CH   O   —           A-286   N   CH   O   5-CH 3             A-287   N   CH   O   5-CH 2 CH 3             A-288   N   CH   O   5-CH 2 CH 2 CH 3             A-289   N   CH   O   5-CH(CH 3 ) 2             A-290   N   CH   O   5-CH 2 CH 2 CH 2 CH 3             A-291   N   CH   O   5-CH 2 CH(CH 3 ) 2             A-292   N   CH   O   5-CH(CH 3 ) 3             A-293   N   CH   O   5-F           A-294   N   CH   O   5-Cl           A-295   N   CH   O   5-Br           A-296   N   CH   O   5-I           A-297   N   CH   O   5-CF 3             A-298   N   CH   O   5-OCF 3             A-299   N   CH   O   5-OCH 3             A-300   N   CH   O   5-OCH 2 CH 3             A-301   N   CH   O   5-OCH 2 CH 2 CH 3             A-302   N   CH   O   5-OCH(CH 3 ) 2             A-303   N   CH   O   5-NO 2             A-304   N   CH   O   5-NH 2             A-305   N   CH   O   5-NH(C}O)CH 3             A-306   N   CH   O   6-CH 3             A-307   N   CH   O   6-CH 2 CH 3             A-308   N   CH   O   6-CH 2 CH 2 CH 3             A-309   N   CH   O   6-CH(CH 3 ) 2             A-310   N   CH   O   6-CH 2 CH 2 CH 2 CH 3             A-311   N   CH   O   6-CH 2 CH(CH 3 ) 2             A-312   N   CH   O   6-CH(CH 3 ) 3             A-313   N   CH   O   6-F           A-314   N   CH   O   6-Cl           A-315   N   CH   O   6-Br           A-316   N   CH   O   6-I           A-317   N   CH   O   6-CF 3             A-318   N   CH   O   6-OCF 3             A-319   N   CH   O   6-OCH 3             A-320   N   CH   O   6-OCH 2 CH 3             A-321   N   CH   O   6-OCH 2 CH 2 CH 3             A-322   N   CH   O   6-OCH(CH 3 ) 2             A-323   N   CH   O   6-NO 2             A-324   N   CH   O   6-NH 2             A-325   N   CH   O   6-NH(C}O)CH 3             A-326   N   CH   O   7-CH 3             A-327   N   CH   O   7-CH 2 CH 3             A-328   N   CH   O   7-CH 2 CH 2 CH 3             A-329   N   CH   O   7-CH(CH 3 ) 2             A-330   N   CH   O   7-CH 2 CH 2 CH 2 CH 3             A-331   N   CH   O   7-CH 2 CH(CH 3 ) 2             A-332   N   CH   O   7-CH(CH 3 ) 3             A-333   N   CH   O   7-F           A-334   N   CH   O   7-Cl           A-335   N   CH   O   7-Br           A-336   N   CH   O   7-I           A-337   N   CH   O   7-CF 3             A-338   N   CH   O   7-OCF 3             A-339   N   CH   O   7-OCH 3             A-340   N   CH   O   7-OCH 2 CH 3             A-341   N   CH   O   7-OCH 2 CH 2 CH 3             A-342   N   CH   O   7-OCH(CH 3 ) 2             A-343   N   CH   O   7-NO 2             A-344   N   CH   O   7-NH 2             A-345   N   CH   O   7-NH(C}O)CH 3                        
 
      Table 41  
      Compounds of the formula I.6  
                 
 
 wherein X is hydrogen, p is 2, R 1  and R 2  are hydrogen, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B. 
 
      Table 42  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is methyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 43  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is ethyl, Et is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 44  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is i-propyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 45  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-propyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 46  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 47  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-butyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 48  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is i-butyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 49  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is tert-butyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 50  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is phenyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 51  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  and R 2  are hydrogen, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 52  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is methyl, E′ is oxygen and (R c )q is in the 4-position and corresponds in each case to a row of Table B.  
      Table 53  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is ethyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 54  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-propyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 55  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-propyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 56  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 57  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-butyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 58  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-butyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 59  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is tert-butyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 60  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is phenyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 61  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  and R 2  are hydrogen, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 62  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is methyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 63  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is ethyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 64  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-propyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 65  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-propyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 66  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 67  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-butyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 68  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-butyl, E′ is oxygen and (R c )q is in the 4-position and corresponds in each case to a row of Table B.  
      Table 69  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is tert-butyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 70  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is phenyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 71  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  and R 2  are hydrogen, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 72  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is methyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 73  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is ethyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 74  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-propyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 75  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-propyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 76  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 77  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-butyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 78  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-butyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 79  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is tert-butyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 80  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is phenyl, E′ is oxygen and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 81  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  and R 2  are hydrogen, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 82  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is methyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 83  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is ethyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 84  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is i-propyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 85  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-propyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 86  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 87  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-butyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 88  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is i-butyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 89  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is tert-butyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 90  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is phenyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 91  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  and R 2  are hydrogen, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 92  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is methyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 93  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is ethyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 94  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-propyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 95  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-propyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 96  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 97  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-butyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 98  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-butyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 99  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is tert-butyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 100  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is phenyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 101  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  and R 2  are hydrogen, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 102  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is methyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 103  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is ethyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 104  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-propyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 105  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-propyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 106  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 107  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-butyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 108  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-butyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 109  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is tert-butyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 110  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is phenyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 111  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  and R 2  are hydrogen, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 112  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is methyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 113  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is ethyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 114  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-propyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 115  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-propyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 116  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 117  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-butyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 118  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-butyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 119  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is tert-butyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 120  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is phenyl, E′ is oxygen and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 121  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  and R 2  are hydrogen, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 122  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is methyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 123  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is ethyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 124  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is i-propyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 125  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-propyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 126  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 127  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-butyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 128  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is i-butyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 129  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is tert-butyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 130  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is phenyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 131  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  and R 2  are hydrogen, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 132  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is methyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 133  
      Compounds of the formula I.6 wherein X is hydrogen, P is 4, R 1  is hydrogen and R 2  is ethyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 134  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-propyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 135  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-propyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 136  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 137  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-butyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 138  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-butyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 139  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is tert-butyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 140  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is phenyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 141  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  and R 2  are hydrogen, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 142  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is methyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 143  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is ethyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 144  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-propyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 145  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-propyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 146  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 147  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-butyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 148  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-butyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 149  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is tert-butyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 150  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is phenyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 151  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  and R 2  are hydrogen, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 152  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is methyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 153  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is ethyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 154  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-propyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 155  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-propyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 156  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 157  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-butyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 158  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-butyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 159  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is tert-butyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 160  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is phenyl, E′ is sulfur and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 161  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  and R 2  are hydrogen, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 162  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is methyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 163  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is ethyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 164  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is i-propyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 165  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-propyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 166  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 167  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-butyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 168  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is i-butyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 169  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is tert-butyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 170  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is phenyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 171  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  and R 2  are hydrogen, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 172  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is methyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 173  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is ethyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 174  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-propyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 175  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-propyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 176  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 177  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-butyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 178  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-butyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 179  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is tert-butyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 180  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is phenyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 181  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  and R 2  are hydrogen, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 182  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is methyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 183  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is ethyl, E′ is sulfur and R c  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 184  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-propyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 185  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-propyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 186  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 187  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-butyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 188  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-butyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 189  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is tert-butyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 190  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is phenyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 191  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  and R 2  are hydrogen, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 192  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is methyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 193  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is ethyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 194  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-propyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 195  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-propyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 196  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 197  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-butyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 198  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-butyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 199  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is tert-butyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 200  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is phenyl, E′ is sulfur and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 201  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  and R 2  are hydrogen, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 202  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is methyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 203  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is ethyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 204  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is i-propyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 205  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-propyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 206  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 207  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-butyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 208  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is i-butyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 209  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is tert-butyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 210  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is phenyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 211  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  and R 2  are hydrogen, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 212  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is methyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 213  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is ethyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 214  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-propyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 215  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-propyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 216  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 217  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-butyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 218  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-butyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 219  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is tert-butyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 220  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is phenyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 221  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  and R 2  are hydrogen, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 222  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is methyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 223  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is ethyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 224  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-propyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 225  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-propyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 226  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 227  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-butyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 228  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-butyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 229  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is tert-butyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 230  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is phenyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 231  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  and R 2  are hydrogen, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 232  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is methyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 233  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is ethyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 234  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-propyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 235  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-propyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 236  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 237  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-butyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 238  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-butyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 239  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is tert-butyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 240  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is phenyl, E′ is NH and (R c ) q  is in the 4-position and corresponds in each case to a row of Table B.  
      Table 241  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  and R 2  are hydrogen, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 242  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is methyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 243  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is ethyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 244  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is i-propyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 245  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-propyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 246  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 247  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-butyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 248  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is i-butyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 249  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is tert-butyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 250  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is phenyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 251  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  and R 2  are hydrogen, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 252  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is methyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 253  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is ethyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 254  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-propyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 255  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-propyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 256  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 257  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-butyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 258  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-butyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 259  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is tert-butyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 260  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is phenyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 261  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  and R 2  are hydrogen, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 262  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is methyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 263  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is ethyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 264  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-propyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 265  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-propyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 266  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 267  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-butyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 268  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-butyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 269  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is tert-butyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 270  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is phenyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 271  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  and R 2  are hydrogen, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 272  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is methyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 273  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is ethyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 274  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-propyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 275  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-propyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 276  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 277  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-butyl, E′ is NH and R c  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 278  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-butyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 279  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is tert-butyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
      Table 280  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is phenyl, E′ is NH and (R c ) q  is in the 5-position and corresponds in each case to a row of Table B.  
                   TABLE B                              (1.6)                                                               Nr.   (R c ) q                         B-1   —           B-2   CH 3             B-3   CH 2 CH 3             B-4   CH 2 CH 2 CH 3             B-5   CH (CH 3 ) 2             B-6   C (CH 3 ) 3             B-7   Cl           B-8   Br           B-9   CH 2 OCH 3             B-10   COOCH 3             B-11   C 6 H 5             B-12   2-F-C 6 H 4             B-13   3-F-C 6 H 4             B-14   4-F-C 6 H 4             B-15   2-Cl-C 6 H 4             B-16   3-Cl-C 6 H 4             B-17   4-C 6 H 4             B-18   2-CH 3 -C 6 H 4             B-19   3 -CH 3 -C 6 H 4             B-20   4-CH 3 -C 6 H 4             B-21   2,3-(CH 3 ) 2 -C 6 H 3             B-22   2,4-(CH 3 ) 2 -C 6 H 3             B-23   2,5-(CH 3 ) 2 -C 6 H 3             B-24   3,4-(CH 3 ) 2 -C 6 H 3             B-25   3,5-(CH 3 ) 2 -C 6 H 3             B-26   2,3-Cl 2 -C 6 H 3             B-27   2,4-Cl 2 -C 6 H 3             B-28   2,5-Cl 2 -C 6 H 3             B-29   3,4-Cl 2 -C 6 H 3             B-30   3,5-Cl 2 -C 6 H 3             B-31   2,3-F 2 -C 6 H 3             B-32   2,4-F 2 -C 6 H 3             B-33   2,5-F 2 -C 6 H 3             B-34   3,4-F 2 -C 6 H 3             B-35   3,5-F 2 -C 6 H 3             B-36   2-F-3-Cl-C 6 H 3             B-37   2-F-4-Cl-C 6 H 3             B-38   2-F-5-Cl-C 6 H 3             B-39   3-F-4-Cl-C 6 H 3             B-40   3-F-5-Cl-C 6 H 3             B-41   2-Cl-3-F-C 6 H 3             B-42   2-Cl-4-F-C 6 H 3             B-43   2-Cl-5-F-C 6 H 3             B-44   3-Cl-4-F-C 6 H 3             B-45   3-Cl-5-F-C 6 H 3             B-46   2-F-3-CH 3 -C 6 H 3             B-47   2-F-4-CH 3 -C 6 H 3             B-48   2-F-5-CH 3 -C 6 H 3             B-49   3-F-4-CH 3 -C 6 H 3             B-50   3-F-5-CH 3 -C 6 H 3             B-51   2-CH 3 -3-F-C 6 H 3             B-52   2-CH 3 -4-F-C 6 H 3             B-53   2-CH 3 -5-F-C 6 H 3             B-54   3-CH 3 -4-F-C 6 H 3             B-55   3-CH 3 -5-F-C 6 H 3             B-56   2 -Cl-3-CH 3 -C 6 H 3             B-57   2-Cl-4-CH 3 -C 6 H 3             B-58   2-Cl-5-CH 3 -C 6 H 3             B-59   3-Cl-4-CH 3 -C 6 H 3             B-60   3-Cl-S -CH 3-C   6 H 3             B-61   2-CH 3 -3-Cl-C 6 H 3             B-62   2-CH 3 -4-Cl-C 6 H 3             B-63   2-CH 3 -5-Cl-C 6 H 3             B-64   3 -CH 3 -4-Cl-C 6 H 3             B-65   3-CH 3 -5-Cl-C 6 H 3             B-66   2,3,4-(CH 3 ) 3 -C 6 H 2             B-67   2,3,5-(CH 3 ) 3 -C 6 H 2             B-68   2,3,6-(CH 3 ) 3 -C 6 H 2             B-69   2,4,5-(CH 3 ) 3 -C 6 H 2             B-70   2,4,6-(CH 3 ) 3 -C 6 H 2             B-71   3,4,5-(CH 3 ) 3 -C 6 H 2             B-72   3,4,6-(CH 3 ) 3 -C 6 H 2             B-73   2,3,4-F 3 -C6H 2             B-74   2,3,5-F 3 -C 6 H 2             B-75   2,3,6-F 3 -C 6 H 2             B-76   2,4,5-F 3 -C 6 H 2             B-77   2,4,6-F 3 -C 6 H 2             B-78   3,4,5-F 3 -C 6 H 2             B-79   3,4,6-F 3 -C 6 H 2             B-80   2,3,4-Cl 3 -C 6 H 2             B-81   2,3,5-Cl 3 -C 6 H 2             B-82   2,3,6-Cl 3 -C 6 H 2             B-83   2,4,5-Cl 3 -C 6 H 2             B-84   2,4,6-Cl 3 -C 6 H 2             B-85   3,4,5-Cl 3 -C 6 H 2             B-86   3,4,6-Cl 3 -C 6 H 2             B-87   2-Cl-3,4-(CH 3 ) 2 -C 6 H 2             B-88   3-Cl-2,4-(CH 3 ) 2 -C 6 H 2             B-89   4-Cl-2,3-(CH 3 ) 2 -C 6 H 2             B-90   2-Cl-3,5-(CH 3 ) 2 -C 6 H 2             B-91   3-Cl-2,5-(CH 3 ) 2 -C 6 H 2             B-92   5-Cl-2,3-(CH 3 ) 2 -C 6 H 2             B-93   2-Cl-3,6-(CH 3 ) 2 -C 6 H 2             B-94   3-Cl-2,6-(CH 3 ) 2 -C 6 H 2             B-95   6-Cl-2,3-(CH 3 ) 2 -C 6 H 2             B-96   2-Cl-4,5-(CH 3 ) 2 -C 6 H 2             B-97   4-Cl-2,5-(CH 3 ) 2 -C 6 H 2             B-98   5-Cl-2,4-(CH 3 ) 2 -C 6 H 2             B-99   2-Cl-4,6-(CH 3 ) 2 -C 6 H 2             B-100   4-Cl-2,6-(CH 3 ) 2 -C 6 H 2             B-101   6-Cl-2,4-(CH 3 ) 2 -C 6 H 2             B-102   3-Cl-4,5-(CH 3 ) 2 -C 6 H 2             B-103   4-Cl-3,5-(CH 3 ) 2 -C 6 H 2             B-104   5-Cl-3,4-(CH 3 ) 2 -C 6 H 2             B-105   3-Cl-4,6-(CH 3 ) 2 -C 6 H 2             B-106   4-Cl-3,6-(CH 3 ) 2 -C 6 H 2             B-107   6-Cl-3,4-(CH 3 ) 2 -C 6 H 2             B-108   3-Cl-5,6-(CH 3 ) 2 -C 6 H 2             B-109   5-Cl-3,6-(CH 3 ) 2 -C 6 H 2             B-110   6-Cl-3,5-(CH 3 ) 2 -C 6 H 2             B-111   2-F-3,4-(CH 3 ) 2 -C 6 H 2             B-112   3-F-2,4-(CH 3 ) 2 -C 6 H 2             B-113   4-F-2,3-(CH 3 ) 2 -C 6 H 2             B-114   2-F-3,5-(CH 3 ) 2 -C 6 H 2             B-115   3-F-2,5-(CH 3 ) 2 -C 6 H 2             B-116   5-F-2,3-(CH 3 ) 2 -C 6 H 2             B-117   2-F-3,6-(CH 3 ) 2 -C 6 H 2             B-118   3-F-2,6-(CH 3 ) 2 -C 6 H 2             B-119   6-F-2,3-(CH 3 ) 2 -C 6 H 2             B-120   2-F-4,5-(CH 3 ) 2 -C 6 H 2             B-121   4-F-2,5-(CH 3 ) 2 -C 6 H 2             B-122   5-F-2,4-(CH 3 ) 2 -C 6 H 2             B-123   2-F-4,6-(CH 3 ) 2 -C 6 H 2             B-124   4-F-2,6-(CH 3 ) 2 -C 6 H 2             B-125   6-F-2,4-(CH 3 ) 2 -C 6 H 2             B-126   3-F-4,5-(CH 3 ) 2 -C 6 H 2             B-127   4-F-3,5-(CH 3 ) 2 -C 6 H 2             B-128   5-F-3,4-(CH 3 ) 2 -C 6 H 2             B-129   3-F-4,6-(CH 3 ) 2 -C 6 H 2             B-130   4-F-3,6-(CH 3 ) 2 -C 6 H 2             B-131   6-F-3,4-(CH 3 ) 2 -C 6 H 2             B-132   3-F-5,6-(CH 3 ) 2 -C 6 H 2             B-133   5-F-3,6-(CH 3 ) 2 -C 6 H 2             B-134   6-F-3,5-(CH 3 ) 2 -C 6 H 2             B-135   2-Cl-3,4-F 2 -C 6 H 2             B-136   3-Cl-2,4-F 2 -C 6 H 2             B-137   4-Cl-2,3-F 2 -C 6 H 2             B-138   2-Cl-3,5-F 2 -C 6 H 2             B-139   3-Cl-2,5-F 2 -C 6 H 2             B-140   5-Cl-2,3-F 2 -C 6 H 2             B-141   2-Cl-3,6-F 2 -C 6 H 2             B-142   3-Cl-2,6-F 2 -C 6 H 2             B-143   6-Cl-2,3-F 2 -C 6 H 2             B-144   2-Cl-4,5-F 2 -C 6 H 2             B-145   4-Cl-2,5-F 2 -C 6 H 2             B-146   5-Cl-2,4-F 2 -C 6 H 2             B-147   2-Cl-4,6-F 2 -C 6 H 2             B-148   4-Cl-2,6-F 2 -C 6 H 2             B-149   6-Cl-2,4-F 2 -C 6 H 2             B-150   3-Cl-4,5-F 2 -C 6 H 2             B-151   4-Cl-3,5-F 2 -C 6 H 2             B-152   5-Cl-3,4-F 2 -C 6 H 2             B-153   3-Cl-4,6-F 2 -C 6 H 2             B-154   4-Cl-3,6-F 2 -C 6 H 2             B-155   6-Cl-3,4-F 2 -C 6 H 2             B-156   3-Cl-5,6-F 2 -C 6 H 2             B-157   5-Cl-3,6-F 2 -C 6 H 2             B-158   6-Cl-3,5-F 2 -C 6 H 2             B-159   2-F-3,4-Cl 2 -C 6 H 2             B-160   3-F-2,4-Cl 2 -C 6 H 2             B-161   4-F-2,3-Cl 2 -C 6 H 2             B-162   2-F-3,5-Cl 2 -C 6 H 2             B-163   3-F-2,5-Cl 2 -C 6 H 2             B-164   5-F-2,3-Cl 2 -C 6 H 2             B-165   2-F-3,6-Cl 2 -C 6 H 2             B-166   3-F-2,6-Cl 2 -C 6 H 2             B-167   6-F-2,3-Cl 2 -C 6 H 2             B-168   2-F-4,5-Cl 2 -C 6 H 2             B-169   4-F-2,5-Cl 2 -C 6 H 2             B-170   5-F-2,4-Cl 2 -C 6 H 2             B-171   2-F-4,6-Cl 2 -C 6 H 2             B-172   4-F-2,6-Cl 2 -C 6 H 2             B-173   6-F-2,4-Cl 2 -C 6 H 2             B-174   3-F-4,5-Cl 2 -C 6 H 2             B-175   4-F-3,5-Cl 2 -C 6 H 2             B-176   5-F-3,4-Cl 2 -C 6 H 2             B-177   3-F-4,6-Cl 2 -C 6 H 2             B-178   4-F-3,6-Cl 2 -C 6 H 2             B-179   6-F-3,4-Cl 2 -C 6 H 2             B-180   3-F-5,6-Cl 2 -C 6 H 2             B-181   5-F-3,6-Cl 2 -C 6 H 2             B-182   6-F-3,5-Cl 2 -C 6 H 2             B-183   2-CH 3 -3,4-F 2 -C 6 H 2             B-184   3-CH 3 -2,4-F 2 -C 6 H 2             B-185   4-CH 3 -2,3-F 2 -C 6 H 2             B-186   2-CH 3 -3,5-F 2 -C 6 H 2             B-187   3-CH 3 -2,5-F 2 -C 6 H 2             B-188   5-CH 3 -2,3-F 2 -C 6 H 2             B-189   2-CH 3 -3,6-F 2 -C 6 H 2             B-190   3-CH 3 -2,6-F 2 -C 6 H 2             B-191   6-CH 3 -2,3-F 2 -C 6 H 2             B-192   2-CH 3 -4,5-F 2 -C 6 H 2             B-193   4-CH 3 -2,5-F 2 -C 6 H 2             B-194   5-CH 3 -2,4-F 2 -C 6 H 2             B-195   2-CH 3 -4,6-F 2 -C 6 H 2             B-196   4-CH 3 -2,6-F 2 -C 6 H 2             B-197   6-CH 3 -2,4-F 2 -C 6 H 2             B-198   3-CH 3 -4,5-F 2 -C 6 H 2             B-199   4-CH 3 -3,5-F 2 -C 6 H 2             B-200   5-CH 3 -3,4-F 2 -C 6 H 2             B-201   3-CH 3 -4,6-F 2 -C 6 H 2             B-202   4-CH 3 -3,6-F 2 -C 6 H 2             B-203   6-CH 3 -3,4-F 2 -C 6 H 2             B-204   3-CH 3 -5,6-F 2 -C 6 H 2             B-205   5-CH 3 -3,6-F 2 -C 6 H 2             B-206   6-CH 3 -3,5-F 2 -C 6 H 2             B-207   2-CH 3 -3,4-CH 2 -C 6 H 2             B-208   3-CH 3 -2,4-Cl 2 -C 6 H 2             B-209   4-CH 3 -2,3-Cl 2 -C 6 H 2             B-210   2-CH 3 -3,5-Cl 2 -C 6 H 2             B-211   3-CH 3 -2,5-Cl 2 -C 6 H 2             B-212   5-CH 3 -2,3-Cl 2 -C 6 H 2             B-213   2-CH 3 -3,6-Cl 2 -C 6 H 2             B-214   3-CH 3 -2,6-Cl 2 -C 6 H 2             B-215   6-CH 3 -2,3-Cl 2 -C 6 H 2             B-216   2-CH 3 -4,5-Cl 2 -C 6 H 2             B-217   4-CH 3 -2,5-Cl 2 -C 6 H 2             B-218   5-CH 3 -2,4-Cl 2 -C 6 H 2             B-219   2-CH 3 -4,6-Cl 2 -C 6 H 2             B-220   4-CH 3 -2,6-Cl 2 -C 6 H 2             B-221   6-CH 3 -2,4-Cl 2 -C 6 H 2             B-222   3-CH 3 -4,5-Cl 2 -C 6 H 2             B-223   4-CH 3 -3,5-Cl 2 -C 6 H 2             B-224   5-CH 3 -3,4-Cl 2 -C 6 H 2             B-225   3-CH 3 -4,6-Cl 2 -C 6 H 2             B-226   4-CH 3 -3,6-Cl 2 -C 6 H 2             B-227   6-CH 3 -3,4-Cl 2 -C 6 H 2             B-228   3-CH 3 -5,6-Cl 2 -C 6 H 2             B-229   5-CH 3 -3,6-CH 2 -C 6 H 2             B-230   6-CH 3 -3,5-CH 2 -C 6 H 2                        
 
      Table 281  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  and R 2  are hydrogen, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
                 
 
      Table 282  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is methyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 283  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is ethyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 284  
      Compounds of the formula I.6 wherein X is-hydrogen, p is 2, R 1  is hydrogen and R 2  is i-propyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 285  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-propyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 286  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 287  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-butyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 288  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is i-butyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 289  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is tert-butyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 290  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is phenyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 291  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  and R 2  are hydrogen, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 292  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is methyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 293  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is ethyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 294  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-propyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 295  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-propyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 296  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 297  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-butyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 298  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-butyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 299  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is tert-butyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 300  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is phenyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 301  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  and R 2  are hydrogen, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 302  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is methyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 303  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is ethyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 304  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-propyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 305  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-propyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 306  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 307  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-butyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 308  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-butyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 309  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is tert-butyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 310  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is phenyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 311  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  and R 2  are hydrogen, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 312  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is methyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 313  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is ethyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 314  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-propyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 315  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-propyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 316  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 317  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-butyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 318  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-butyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 319  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is tert-butyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 320  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is phenyl, E′ is oxygen, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 321  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  and R 2  are hydrogen, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 322  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is methyl, E′ is sulfur and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 323  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is ethyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 324  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is i-propyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 325  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-propyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 326  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 327  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-butyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 328  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is i-butyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 329  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is tert-butyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 330  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is phenyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 331  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  and R 2  are hydrogen, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 332  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is methyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 333  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is ethyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 334  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-propyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 335  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-propyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 336  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 337  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-butyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 338  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-butyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 339  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is tert-butyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 340  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is phenyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 341  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  and R 2  are hydrogen, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 342  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is methyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 343  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is ethyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 344  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-propyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 345  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-propyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 346  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 347  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-butyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 348  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-butyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 349  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is tert-butyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 350  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is phenyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 351  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  and R 2  are hydrogen, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 352  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is methyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 353  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is ethyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 354  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-propyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 355  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-propyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 356  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 357  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-butyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 358  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-butyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 359  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is tert-butyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 360  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is phenyl, E′ is sulfur, q is 2 and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 361  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  and R 2  are hydrogen, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 362  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is methyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 363  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is ethyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 364  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is i-propyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 365  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-propyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 366  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 367  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-butyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 368  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is i-butyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 369  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is tert-butyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 370  
      Compounds of the formula I.6 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is phenyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 371  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  and R 2  are hydrogen, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 372  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is methyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 373  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is ethyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 374  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-propyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 375  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-propyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 376  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 377  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-butyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 378  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-butyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 379  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is tert-butyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 380  
      Compounds of the formula I.6 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is phenyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 381  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  and R 2  are hydrogen, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 382  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is methyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 383  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is ethyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 384  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-propyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 385  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-propyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 386  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 387  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-butyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 388  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-butyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 389  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is tert-butyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 390  
      Compounds of the formula I.6 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is phenyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 391  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  and R 2  are hydrogen, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 392  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is methyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 393  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is ethyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 394  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-propyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 395  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-propyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 396  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 397  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-butyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 398  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-butyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 399  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is tert-butyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
      Table 400  
      Compounds of the formula I.6 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is phenyl, E′ is NH and (R c ) q  for a compound corresponds in each case to a row of Table C.  
                   TABLE C                              (I.6)                                                                   Nr.   R c  (4-Position)   R c  (5-Position)                       C-1   CH 3     CH 3             C-2   CH 2 CH 3     CH 3             C-3   CH 2 CH 2 CH 3     CH 3             C-4   CH(CH 3 ) 2     CH 3             C-5   C(CH 3 ) 3     CH 3             C-6   Cl   CH 3             C-7   Br   CH 3             C-8   CH 2 OCH 3     CH 3             C-9   COOCH 3     CH 3             C-10   C 6 H 5     CH 3             C-11   2-F-C 6 H 4     CH 3             C-12   3-F-C 6 H 4     CH 3             C-13   4-F-C 6 H 4     CH 3             C-14   2-Cl-C 6 H 4     CH 3             C-15   3-Cl-C 6 H 4     CH 3             C-16   4-Cl-C 6 H 4     CH 3             C-17   2-CH 3 -C 6 H 4     CH 3             C-18   3-CH 3 -C 6 H 4     CH 3             C-19   4-CH 3 -C 6 H 4     CH 3             C-20   CH 3     CH 2 CH 3             C-21   CH 2 CH 3     CH 2 CH 3             C-22   CH 2 CH 2 CH 3     CH 2 CH 3             C-23   CH(CH 3 ) 2     CH 2 CH 3             C-24   C(CH 3 ) 3     CH 2 CH 3             C-25   Cl   CH 2 CH 3             C-26   Br   CH 2 CH 3             C-27   CH 2 0CH 3     CH 2 CH 3             C-28   COOCH 3     CH 2 CH 3             C-29   C 6 H 5     CH 2 CH 3             C-30   2-F-C 6 H 4     CH 2 CH 3             C-31   3-F-C 6 H 4     CH 2 CH 3             C-32   4-F-C 6 H 4     CH 2 CH 3             C-33   2-Cl-C 6 H 4     CH 2 CH 3             C-34   3-Cl-C 6 H 4     CH 2 CH 3             C-35   4-Cl-C 6 H 4     0H2CH 3             C-36   2-CH 3 -C 6 H 4     CH 2 CH 3             C-37   3-CH 3 -C 6 H 4     CH 2 CH 3             C-38   4-CH 3 -C 6 H 4     CH 2 CH 3             C-39   CH 3     CH 2 CH 2 CH 3             C-40   CH 2 CH 3     CH 2 CH 2 CH 3             C-41   CH 2 CH 2 CH 3     CH 2 CH 2 CH 3             C-42   CH(CH 3 ) 2     CH 2 CH 2 CH 3             C-43   C(CH 3 ) 3     CH 2 CH 2 CH 3             C-44   Cl   CH 2 CH 2 CH 3             C-45   Br   CH 2 CH 2 CH 3             C-46   CH 2 OCH 3     CH 2 CH 2 CH 3             C-47   COOCH 3     CH 2 CH 2 CH 3             C-48   C 6 H 5     CH 2 CH 2 CH 3             C-49   2-F-C 6 H 4     CH 2 CH 2 CH 3             C-50   3-F-C 6 H 4     CH 2 CH 2 CH 3             C-51   4-F-C 6 H 4     CH 2 CH 2 CH 3             C-52   2-Cl-C 6 H 4     CH 2 CH 2 CH 3             C-53   3-Cl-C 6 H 4     CH 2 CH 2 CH 3             C-54   4-Cl-C 6 H 4     CH 2 CH 2 CH 3             C-55   2-CH 3 -C 6 H 4             C-56   3-CH 3 -C 6 H 4             C-57   4-CH 3 -C 6 H 4             C-58   CH 3             C-59   CH 2 CH 3             C-60   CH 2 CH 2 CH 3             C-61   CH(CH 3 ) 2     CH(CH 3 ) 2             C-62   C(CH 3 ) 3     CH(CH 3 ) 2             C-63   Cl   CH (CH 3 ) 2             C-64   Br   CH (CH 3 ) 2             C-65   CH 2 OCH 3     CH (CH 3 ) 2             C-66   COOCH 3     CH (CH 3 ) 2             C-67   C 6 H 5     CH(CH 3 ) 2             C-68   2-F-C 6 H 4     CH(CH 3 ) 2             C-69   3-F-C 6 H 4     CH(CH 3 ) 2             C-70   4-F-C 6 H 4     CH(CH 3 ) 2             C-71   2-Cl-C 6 H 4     CH(CH 3 ) 2             C-72   3-Cl-C 6 H 4     CH(CH 3 ) 2             C-73   4-Cl-C 6 H 4     CH(CH 3 ) 2             C-74   2-CH 3 -C 6 H 4     CH(CH 3 ) 2             C-75   3-CH 3 -C 6 H 4     CH(CH 3 ) 2             C-76   4-CH 3 -C 6 H 4     CH(CH 3 ) 2             C-77   CH 3     C(CH 3 ) 3             C-78   CH 2 CH 3     C(CH 3 ) 3             C-79   CH 2 CH 2 CH 3     C(CH 3 ) 3             C-80   CH(CH 3 ) 2     C(CH 3 ) 3             C-81   C(CH 3 ) 3     C(CH 3 ) 3             C-82   Cl   C(Cl13) 3             C-83   Br   C(CH 3 ) 3             C-84   CH 2 OCH 3     C(CH 3 ) 3             C-85   COOCH 3     C(CH 3 ) 3             C-86   C 6 H 5     C(CH 3 ) 3             C-87   2-F-C 6 H 4     C(CH 3 ) 3             C-88   3-F-C 6 H 4     C(CH 3 ) 3             C-89   4-F-C 6 H 4     C(CH 3 ) 3             C-90   2-Cl-C 6 H 4     C(CH 3 ) 3             C-91   3-Cl-C 6 H 4     C(CH 3 ) 3             C-92   4-Cl-C 6 H 4     C(CH 3 ) 3             C-93   2-CH 3 -C 6 H 4     C(CH 3 ) 3             C-94   3-CH 3 -C 6 H 4     C(CH 3 ) 3             C-95   4-CH 3 -C 6 H 4     C(CH 3 ) 3             C-96   CH 3     Cl           C-97   CH 2 CH 3     Cl           C-98   CH 2 CH 2 CH 3     Cl           C-99   CH(CH 3 ) 2     Cl           C-100   C(CH 3 ) 3     Cl           C-101   Cl   Cl           C-102   Br   Cl           C-103   CH 2 OCH 3     Cl           C-104   COOCH 3     Cl           C-105   C 6 H 5     Cl           C-106   2-F-C 6 H 4     Cl           C-107   3-F-C 6 H 4     Cl           C-108   4-F-C 6 H 4     Cl           C-109   2-Cl-C 6 H 4     Cl           C-110   3-Cl-C 6 H 4     Cl           C-111   4-Cl-C 6 H 4     Cl           C-112   2-CH 3 -C 6 H 4     Cl           C-113   3-CH 3 -C 6 H 4     Cl           C-114   4-CH 3 -C 6 H 4     Cl           C-115   CH 3     Br           C-116   CH 2 CH 3     Br           C-117   CH 2 CH 2 CH 3     Br           C-118   CH(CH 3 ) 2     Br           C-119   C(CH 3 ) 3     Br           C-120   Cl   Br           C-121   Br   Br           C-122   CH 2 OCH 3     Br           C-123   COOCH 3     Br           C-124   C 6 H 5     Br           C-125   2-F-C 6 H 4     Br           C-126   3-F-C 6 H 4     Br           C-127   4-F-C 6 H 4     Br           C-128   2-Cl-C 6 H 4     Br           C-129   3-Cl-C 6 H 4     Br           C-130   4-Cl-C 6 H 4     Br           C-131   2-CH 3 -C 6 H 4     Br           C-132   3-CH 3 -C 6 H 4     Br           C-133   4-CH 3 -C 6 H 4     Br           C-134   CH 3     CH 2 OCH 3             C-135   CH 2 CH 3     CH 2 OCH 3             C-136   CH 2 CH 2 CH 3     CH 2 OCH 3             C-137   CH(CH 3 ) 2     CH 2 OCH 3             C-138   C(CH 3 ) 3     CH 2 OCH 3             C-139   Cl   CH 2 OCH 3             C-140   Br   CH 2 OCH 3             C-141   CH 2 OCH 3     CH 2 OCH 3             C-142   COOCH 3     CH 2 OCH 3             C-143   C 6 H 5     CH 2 OCH 3             C-144   2-F-C 6 H 4     CH 2 OCH 3             C-145   3-F-C 6 H 4     CH 2 OCH 3             C-146   4-F-C 6 H 4     CH 2 OCH 3             C-147   2-Cl-C 6 H 4     CH 2 OCH 3             C-148   3-Cl-C 6 H 4     CH 2 OCH 3             C-149   4-Cl-C 6 H 4     CH 2 OCH 3             C-150   2-CH 3 -C 6 H 4     CH 2 OCH 3             C-151   3-CH 3 -C 6 H 4     CH 2 OCH 3             C-152   4-CH 3 -C 6 H 4     CH 2 OCH 3             C-153   CH 3     COOCH 3             C-154   CH 2 CH 3     COOCH 3             C-155   CH 2 CH 2 CH 3     COOCH 3             C-156   CH(CH 3 ) 2     COOCH 3             C-157   C(CH 3 ) 3     COOCH 3             C-158   Cl   COOCH 3             C-159   Br   COOCH 3             C-160   CH 2 OCH 3     COOCH 3             C-161   COOCH 3     COOCH 3             C-162   C 6 H 5     COOCH 3             C-163   2-F-C 6 H 4     COOCH 3             C-164   3-F-C 6 H 4     C0OCH 3             C-165   4-F-C 6 H 4     COOCH 3             C-166   2-Cl-C 6 H 4     COOCH 3             C-167   3-Cl-C 6 H 4     COOCH 3             C-168   4-Cl-C 6 H 4     COOCH 3             C-169   2-CH 3 -C 6 H 4     COOCH 3             C-170   3-CH 3 -C 6 H 4     COOCH 3             C-171   4-CH 3 -C 6 H 4     COOCH 3             C-172   CH 3     C 6 H 5             C-173   CH 2 CH 3     C 6 H 5             C-174   CH 2 CH 2 CH 3     C 6 H 5             C-175   CH(CH 3 ) 2     C 6 H 5             C-176   C(CH 3 ) 3     C 6 H 5             C-177   Cl   C 6 H 5             C-178   Br   C 6 H 5             C-179   CH 2 OCH 3     C 6 H 5             C-180   COOCH 3     C 6 H 5             C-181   C 6 H 5     C 6 H 5             C-182   2-F-C 6 H 4             C-183   3-F-C 6 H 4     C 6 H 5             C-184   4-F-C 6 H 4     C 6 H 5             C-185   2-Cl-C 6 H 4     C 6 H 5             C-186   3-Cl-C 6 H 4     C 6 H 5             C-187   4-Cl-C 6 H 4     C 6 H 5             C-188   2-CH 3 -C 6 H 4     C 6 H 5             C-189   3-CH 3 -C 6 H 4     C 6 H 5             C-190   4-CH 3 -C 6 H 4     C 6 H 5             C-191   CH 3     2-F-C 6 H 4             C-192   CH 2 CH 3     2-F-C 6 H 4             C-193   CH 2 CH 2 CH 3     2-F-C 6 H 4             C-194   CH(CH 3 ) 2     2-F-C 6 H 4             C-195   C(CH 3 ) 3     2-F-C 6 H 4             C-196   Cl   2-F-C 6 H 4             C-197   Br   2-F-C 6 H 4             C-198   CH 2 OCH 3     2-F-C 6 H 4             C-199   COOCH 3     2-F-C 6 H 4             C-200   C 6 H 5     2-F-C 6 H 4             C-201   2-F-C 6 H 4     2-F-C 6 H 4             C-202   3-F-C 6 H 4     2-F-C 6 H 4             C-203   4-F-C 6 H 4     2-F-C 6 H 4             C-204   2-Cl-C 6 H 4     2-F-C 6 H 4             C-205   3-Cl-C 6 H 4     2-F-C 6 H 4             C-206   4-Cl-C 6 H 4     2-F-C 6 H 4             C-207   2-CH 3 -C 6 H 4     2-F-C 6 H 4             C-208   3-CH 3 -C 6 H 4     2-F-C 6 H 4             C-209   4-CH 3 -C 6 H 4     2-F-C 6 H 4             C-210   CH 3     3-F-C 6 H 4             C-211   CH 2 CH 3     3-F-C 6 H 4             C-212   CH 2 CH 2 CH 3     3-F-C 6 H 4             C-213   CH(CH 3 ) 2     3-F-C 6 H 4             C-214   C(CH 3 ) 3     3-F-C 6 H 4             C-215   Cl   3-F-C 6 H 4             C-216   Br   3-F-C 6 H 4             C-217   CH 2 OCH 3     3-F-C 6 H 4             C-218   COOCH 3     3-F-C 6 H 4             C-219   C 6 H 5     3-F-C 6 H 4             C-220   2-F-C 6 H 4     3-F-C 6 H 4             C-221   3-F-C 6 H 4     3-F-C 6 H 4             C-222   4-F-C 6 H 4     3-F-C 6 H 4             C-223   2-Cl-C 6 H 4     3-F-C 6 H 4             C-224   3-Cl-C 6 H 4     3-F-C 6 H 4             C-225   4-Cl-C 6 H 4     3-F-C 6 H 4             C-226   2-CH 3 -C 6 H 4     3-F-C 6 H 4             C-227   3-CH 3 -C 6 H 4     3-F-C 6 H 4             C-228   4-CH 3 -C 6 H 4     3-F-C 6 H 4             C-229   CH 3     4-F-C 6 H 4             C-230   CH 2 CH 3     4-F-C 6 H 4             C-231   CH 2 CH 2 CH 3     4-F-C 6 H 4             C-232   CH(CH 3 ) 2     4-F-C 6 H 4             C-233   C(CH 3 ) 3     4-F-C 6 H 4             C-234   Cl   4-F-C 6 H 4             C-235   Br   4-F-C 6 H 4             C-236   CH 2 OCH 3     4-F-C 6 H 4             C-237   COOCH 3     4-F-C 6 H 4             C-238   C 6 H 5     4-F-C 6 H 4             C-239   2-F-C 6 H 4     4-F-C 6 H 4             C-240   3-F-C 6 H 4     4-F-C 6 H 4             C-241   4-F-C 6 H 4     4-F-C 6 H 4             C-242   2-Cl-C 6 H 4     4-F-C 6 H 4             C-243   3-Cl-C 6 H 4     4-F-C 6 H 4             C-244   4-Cl-C 6 H 4     4-F-C 6 H 4             C-245   2-CH 3 -C 6 H 4     4-F-C 6 H 4             C-246   3-CH 3 -C 6 H 4     4-F-C 6 H 4             C-247   4-CH 3 -C 6 H 4     4-F-C 6 H 4             C-248   CH 3     2-Cl-C 6 H 4             C-249   CH 2 CH 3     2-Cl-C 6 H 4             C-250   CH 2 CH 2 CH 3     2-Cl-C 6 H 4             C-251   CH(CH 3 ) 2     2-Cl-C 6 H 4             C-252   C(CH 3 ) 3     2-Cl-C 6 H 4             C-253   Cl   2-Cl-C 6 H 4             C-254   Br   2-Cl-C 6 H 4             C-255   CH 2 OCH 3     2-Cl-C 6 H 4             C-256   COOCH 3     2-Cl-C 6 H 4             C-257   C 6 H 5     2-Cl-C 6 H 4             C-258   2-F-C 6 H 4     2-Cl-C 6 H 4             C-259   3-F-C 6 H 4     2-Cl-C 6 H 4             C-260   4-F-C 6 H 4     2-Cl-C 6 H 4             C-261   2-Cl-C 6 H 4     2-Cl-C 6 H 4             C-262   3-Cl-C 6 H 4     2-Cl-C 6 H 4             C-263   4-Cl-C 6 H 4     2-Cl-C 6 H 4             C-264   2-CH 3 -C 6 H 4     2-Cl-C 6 H 4             C-265   3-CH 3 -C 6 H 4     2-Cl-C 6 H 4             C-266   4-CH 3 -C 6 H 4     2-Cl-C 6 H 4             C-267   CH 3     3-Cl-C 6 H 4             C-268   CH 2 CH 3     3-Cl-C 6 H 4             C-269   CH 2 CH 2 CH 3     3-Cl-C 6 H 4             C-270   CH(CH 3 ) 2     3-Cl-C 6 H 4             C-271   C(CH 3 ) 3             C-272   Cl           C-273   Br   3-Cl-C 6 H 4             C-274   CH 2 OCH 3     3-Cl-C 6 H 4             C-275   COOCH 3     3-Cl-C 6 H 4             C-276   C 6 H 5     3-Cl-C 6 H 4             C-277   2-F-C 6 H 4     3-Cl-C 6 H 4             C-278   3-F-C 6 H 4     3-Cl-C 6 H 4             C-279   4-F-C 6 H 4     3-Cl-C 6 H 4             C-280   2-Cl-C 6 H 4     3-Cl-C 6 H 4             C-281   3-Cl-C 6 H 4     3-Cl-C 6 H 4             C-282   4-Cl-C 6 H 4     3-Cl-C 6 H 4             C-283   2-CH 3 -C 6 H 4     3-Cl-C 6 H 4             C-284   3-CH 3 -C 6 H 4     3-Cl-C 6 H 4             C-285   4-CH 3 -C 6 H 4     3-Cl-C 5 H 4             C-286   CH 3     4-Cl-C 6 H 4             C-287   CH 2 CH 3     4-Cl-C 6 H 4             C-288   CH 2 CH 2 CH 3     4-Cl-C 6 H 4             C-289   CH(CH 3 ) 2     4-Cl-C 6 H 4             C-290   C(CH 3 ) 3     4-Cl-C 6 H 4             C-291   Cl   4-Cl-C 6 H 4             C-292   Br   4-Cl-C 6 H 4             C-293   CH 2 OCH 3     4-Cl-C 6 H 4             C-294   COOCH 3     4-Cl-C 6 H 4             C-295   C 6 H 5     4-Cl-C 6 H 4             C-296   2-F-C 6 H 4     4-Cl-C 6 H 4             C-297   3-F-C 6 H 4     4-Cl-C 6 H 4             C-298   4-F-C 6 H 4     4-Cl-C 6 H 4             C-299   2-Cl-C 6 H 4     4-Cl-C 6 H 4             C-300   3-Cl-C 6 H 4     4-Cl-C 6 H 4             C-301   4-Cl-C 6 H 4     4-Cl-C 6 H 4             C-302   2-CH 3 -C 6 H 4     4-Cl-C 6 H 4             C-303   3-CH 3 -C 6 H 4     4-Cl-C 6 H 4             C-304   4-CH 3 -C 6 H 4     4-Cl-C 6 H 4             C-305   CH 3             C-306   CH 2 CH 3     2-CH 3 -C 6 H 4             C-307   CH 2 CH 2 CH 3     2-CH 3 -C 6 H 4             C-308   CH(CH 3 ) 2     2-CH 3 -C 6 H 4             C-309   C(CH 3 ) 3     2-CH 3 -C 6 H 4             C-311   Cl   2-CH 3 -C 6 H 4             C-312   Br   2-CH 3 -C 6 H 4             C-313   CH 2 OCH 3     2-CH 3 -C 6 H 4             C-314   COOCH 3     2-CH 3 -C 6 H 4             C-315   2-F-C 6 H 4     2-CH 3 -C 6 H 4             C-316   3-F-C 6 H 4     2-CH 3 -C 6 H 4             C-317   4-F-C 6 H 4     2-CH 3 -C 6 H 4             C-318   2-Cl-C 6 H 4     2-CH 3 -C 6 H 4             C-319   3-Cl-C 6 H 4     2-CH 3 -C 6 H 4             C-320   4-Cl-C 6 H 4     2-CH 3 -C 6 H 4             C-321   2-CH 3 -C 6 H 4     2-CH 3 -C 6 H 4             C-322   3-CH 3 -C 6 H 4     2-CH 3             C-323   4-CH 3 -C 6 H 4     2-CH 3 -C 6 H 4             C-324   CH 3     3-CH 3 -C 6 H 4             C-325   CH 2 CH 3     3-CH 3 -C 6 H 4             C-326   CH 2 CH 2 CH 3     3-CH 3 -C 6 H 4             C-327   CH(CH 3 ) 2     3-CH 3 -C 6 H 4             C-328   C(CH 3 ) 3     3-CH 3 -C 6 H 4             C-329   Cl   3-CH 3 -C 6 H 4             C-330   Br   3-CH 3 -C 6 H 4             C-331   CH 2 OCH 3     3-CH 3 -C 6 H 4             C-332   COOCH 3     3-CH 3 -C 6 H 4             C-333   C 6 H 5     3-CH 3 -C 6 H 4             C-334   2-F-C 6 H 4     3-CH 3 -C 6 H 4             C-335   3-F-C 6 H 4     3-CH 3 -C 6 H 4             C-336   4-F-C 6 H 4     3-CH 3 -C 6 H 4             C-337   2-Cl-C 6 H 4     3-CH 3 -C 6 H 4             C-338   3-Cl-C 6 H 4     3-CH 3 -C 6 H 4             C-339   4-Cl-C 6 H 4     3-CH 3 -C 6 H 4             C-340   2-CH 3 -C 6 H 4     3-CH 3 -C 6 H 4             C-341   3-CH 3 -C 6 H 4     3-CH 3 -C 6 H 4             C-342   4-CH 3 -C 6 H 4     3-CH 3 -C 6 H 4             C-343   CH 3     4-CH 3 -C 6 H 4             C-344   CH 2 CH 3     4-CH 3 -C 6 H 4             C-345   CH 2 CH 2 CH 3     4-CH 3 -C 6 H 4             C-346   CH(CH 3 ) 2     4-CH 3 -C 6 H 4             C-347   C(CH 3 ) 3     4-CH 3 -C 6 H 4             C-348   Cl   4-CH 3 -C 6 H 4             C-349   Br   4-CH 3 -C 6 H 4             C-350   CH 2 OCH 3     4-CH 3 -C 6 H 4             C-351   COOCH 3     4-CH 3 -C 6 H 4             C-352   C 6 H 5     4-CH 3 -C 6 H 4             C-353   2-F-C 6 H 4     4-CH 3 -C 6 H 4             C-354   3-F-C 6 H 4     4-CH 3 -C 6 H 4             C-355   4-F-C 6 H 4     4-CH 3 -C 6 H 4             C-356   2-Cl-C 6 H 4     4-CH 3 -C 6 H 4             C-357   3-Cl-C 6 H 4     4-CH 3 -C 6 H 4             C-358   4-Cl-C 6 H 4     4-CH 3 -C 6 H 4             C-359   2-CH 3 -C 6 H 4     4-CH 3 -C 6 H 4             C-360   3-CH 3 -C 6 H 4     4-CH 3 -C 6 H 4             C-361   4-CH 3 -C 6 H 4     4-CH 3 -C 6 H 4                        
 
      Table 401  
      Compounds of the formula I.7 wherein X is hydrogen, p is 2, R 1  and R 2  are hydrogen and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
                 
 
      Table 402  
      Compounds of the formula I.7 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is methyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 403  
      Compounds of the formula I.7 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is ethyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 404  
      Compounds of the formula I.7 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is i-propyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 405  
      Compounds of the formula I.7 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-propyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 406  
      Compounds of the formula I.7 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 407  
      Compounds of the formula I.7 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is n-butyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 408  
      Compounds of the formula I.7 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is i-butyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 409  
      Compounds of the formula I.7 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is tert-butyl and the combination of E and R b  for a compound corresponds in each case to a row of Table D.  
      Table 410  
      Compounds of the formula I.7 wherein X is hydrogen, p is 2, R 1  is hydrogen and R 2  is phenyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 411  
      Compounds of the formula I.7 wherein X is hydrogen, p is 4, R 1  and R 2  are hydrogen and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 412  
      Compounds of the formula I.7 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is methyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 413  
      Compounds of the formula I.7 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is ethyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 414  
      Compounds of the formula I.7 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-propyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 415  
      Compounds of the formula I.7 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-propyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 416  
      Compounds of the formula I.7 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 417  
      Compounds of the formula I.7 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is n-butyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 418  
      Compounds of the formula I.7 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is i-butyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 419  
      Compounds of the formula I.7 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is tert-butyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 420  
      Compounds of the formula I.7 wherein X is hydrogen, p is 4, R 1  is hydrogen and R 2  is phenyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 421  
      Compounds of the formula I.7 wherein X is fluorine, p is 2, R 1  and R 2  are hydrogen and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 422  
      Compounds of the formula I.7 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is methyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 423  
      Compounds of the formula I.7 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is ethyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 424  
      Compounds of the formula I.7 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-propyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 425  
      Compounds of the formula I.7 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-propyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 426  
      Compounds of the formula I.7 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is cyclo-propyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 427  
      Compounds of the formula I.7 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is n-butyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 428  
      Compounds of the formula I.7 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is i-butyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 429  
      Compounds of the formula I.7 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is tert-butyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 430  
      Compounds of the formula I.7 wherein X is fluorine, p is 2, R 1  is hydrogen and R 2  is phenyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 431  
      Compounds of the formula I.7 wherein X is fluorine, p is 4, R 1  and R 2  are hydrogen and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 432  
      Compounds of the formula I.7 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is methyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 433  
      Compounds of the formula I.7 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is ethyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 434  
      Compounds of the formula I.7 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-propyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 435  
      Compounds of the formula I.7 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-propyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 436  
      Compounds of the formula I.7 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is cyclo-propyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 437  
      Compounds of the formula I.7 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is n-butyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 438  
      Compounds of the formula I.7 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is i-butyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 439  
      Compounds of the formula I.7 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is tert-butyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
      Table 440  
      Compounds of the formula I.7 wherein X is fluorine, p is 4, R 1  is hydrogen and R 2  is phenyl and the combination of E and R c  for a compound corresponds in each case to a row of Table D.  
                   TABLE D                              (1.7)                                                                   Nr.   E   R c                         D-1   O   —           D-2   O   CH 3             D-3   O   CH 2 CH 3             D-4   O   CH 2 CH 2 CH 3             D-5   O   CH(CH 3 ) 2             D-6   O   CH 2 CH 2 CH 2 CH 3             D-7   O   CH 2 CH(CH 3 ) 2             D-8   O   C(CH 3 ) 3             D-9   O   F           D-10   O   Cl           D-11   O   Br           D-12   O   I           D-13   O   CF 3             D-14   O   OCF 3             D-15   O   OCH 3             D-16   O   OCH 2 CH 3             D-17   O   OCH 2 CH 2 CH 3             D-18   O   OCH(CH 3 ) 2             D-19   O   NO 2             D-2O   O   NH 2             D-21   O   NH(C}O)CH 3             D-22   S   —           D-23   S   CH 3             D-24   S   CH 2 CH 3             D-25   S   CH 2 CH 2 CH 3             D-26   S   CH(CH 3 ) 2             D-27   S   CH 2 CH 2 CH 2 CH 3             D-28   S   CH 2 CH(CH 3 ) 2             D-29   S   C(CH 3 ) 3             D-30   S   F           D-31   S   Cl           D-32   S   Br           D-33   S   I           D-34   S   CF 3             D-35   S   OCF 3             D-36   S   OCH 3             D-37   S   OCH 2 CH 3             D-38   S   OCH 2 CH 2 CH 3             D-39   S   OCH(CH 3 ) 2             D-40   S   NO 2             D-41   S   NH 2             D-42   S   NH(C}O)CH 3                        
 
      The compounds of the formula I are suitable for efficiently controlling nematodes, insects, and arachnids in crop protection. In particular, they are suitable for controlling the following animal pests:  
      insects from the order of the lepidopterans ( Lepidoptera ), for example  Agrotis ypsilon, Agrotis segetum, Alabama argillacea, Anticarsia gemmatalis, Argyresthia conjugella, Autographa gamma, Bupalus piniarius, Cacoecia murinana, Capua reticulana, Cheimatobia brumata, Choristoneura fumiferana, Choristoneura occidentalis, Cirphis unipuncta, Cydia pomonella, Dendrolimus pini, Diaphania nitidalis, Diatraea grandiosella, Earias insulana, Elasmopalpus lignosellus, Eupoecilia ambiguella, Evetria bouliana, Feltia subterranea, Galleria mellonella, Grapholitha funebrana, Grapholitha molesta, Heliothis armigera, Heliothis virescens, Heliothis zea, Hellula undalis, Hibernia defoliaria, Hyphantria cunea, Hyponomeuta malinellus, Keiferia lycopersicella, Lambdina fiscellaria, Laphygma exigua, Leucoptera coffeella, Leucoptera scitella, Lithocolletis blancardella, Lobesia botrana, Loxostege sticticalis, Lymantria dispar, Lymantria monacha, Lyonetia clerkella, Malacosoma neustria, Mamestra brassicae, Orgyia pseudotsugata, Ostrinia nubilalis, Panolis flammea, Pectinophora gossypiella, Peridroma saucia, Phalera bucephala, Phthorimaea operculella, Phyllocnistis citrella, Pieris brassicae, Plathypena scabra, Plutella xylostella, Pseudoplusia includens, Rhyacionia frustrana, Scrobipalpula absoluta, Sitotroga cerealella, Sparganothis pilleriana, Spodoptera frugiperda, Spodoptera littoralis, Spodoptera litura, Thaumatopoea pityocampa, Tortrix viridana, Trichoplusia ni  and  Zeiraphera canadensis,    
      beetles ( Coleoptera ), for example  Agrilus sinuatus, Agriotes lineatus, Agriotes obscurus, Amphimallus solstitialis, Anisandrus dispar, Anthonomus grandis, Anthonomus pomorum, Atomaria linearis, Blastophagus piniperda, Blitophaga undata, Bruchus rufimanus, Bruchus pisorum, Bruchus lentis, Byctiscus betulae, Cassida nebulosa, Cerotoma trifurcata, Ceuthorrhynchus assimilis, Ceuthorrhynchus napi, Chaetocnema tibialis, Conoderus vespertinus, Crioceris asparagi, Diabrotica longicornis, Diabrotica  12- punctata, Diabrotica virgifera, Epilachna varivestis, Epitrix hirtipennis, Eutinobothrus brasiliensis, Hylobius abietis, Hypera brunneipennis, Hypera postica, Ips typographus, Lema bilineata, Lema melanopus, Leptinotarsa decemlineata, Limonius californicus, Lissorhoptrus oryzophilus, Melanotus communis, Meligethes aeneus, Melolontha hippocastani, Melolontha melolontha, Oulema oryzae, Ortiorrhynchus sulcatus, Otiorrhynchus ovatus, Phaedon cochleariae, Phyllotreta chrysocephala, Phyllophaga  sp.,  Phyllopertha horticola, Phyllotreta nemorum, Phyllotreta striolata, Popillia japonica, Sitona lineatus and Sitophilus granaria,    
      dipterans ( Diptera ), for example  Aedes aegypti, Aedes vexans, Anastrepha ludens, Anopheles maculipennis, Ceratitis capitata, Chrysomya bezziana, Chrysomya hominivorax, Chrysomya macellaria, Contarinia sorghicola, Cordylobia anthropophaga, Culex pipiens, Dacus cucurbitae, Dacus oleae, Dasineura brassicae, Fannia canicularis, Gasterophilus intestinalis, Glossina morsitans, Haematobia irritans, Haplodiplosis equestris, Hylemyia platura, Hypoderma lineata, Liriomyza sativae, Liriomyza trifolii, Lucilia caprina, Lucilia cuprina, Lucilia sericata, Lycoria pectoralis, Mayetiola destructor, Musca domestica, Muscina stabulans, Oestrus ovis, Oscinella frit, Pegomya hysocyami, Phorbia antiqua, Phorbia brassicae, Phorbia coarctata, Rhagoletis cerasi, Rhagoletis pomonella, Tabanus bovinus, Tipula oleracea and Tipula paludosa,    
       thrips  ( Thysanoptera ), e.g.  Frankliniella fusca, Frankliniella occidentalis, Frankliniella tritici, Scirtothrips citri, Thrips oryzae, Thrips palmi  and  Thrips tabaci,    
      hymenopterans ( Hymenoptera ), e.g.  Athalia rosae, Atta cephalotes, Atta sexdens, Atta texana, Hoplocampa minuta, Hoplocampa testudinea, Monomorium pharaonis, Solenopsis geminata and Solenopsis invicta,    
      heteropterans ( Heteroptera ), e.g.  Acrosternum hilare, Blissus leucopterus, Cyrtopeltis notatus, Dysdercus cingulatus, Dysdercus intermedius, Eurygaster integriceps, Euschistus impictiventris, Leptoglossus phyllopus, Lygus lineolaris, Lygus pratensis, Nezara viridula, Piesma quadrata, Solubea insularis  and  Thyanta perditor,    
      homopterans ( Homoptera ), e.g.  Acyrthosiphon onobrychis, Adelges laricis, Aphidula nasturtii, Aphis fabae, Aphis pomi, Aphis sambuci, Brachycaudus cardui, Brevicoryne brassicae, Cerosipha gossypii, Dreyfusia nordmannianae, Dreyfusia piceae, Dysaphis radicola, Dysaulacorthum pseudosolani, Empoasca fabae, Macrosiphum avenae, Macrosiphum euphorbiae, Macrosiphon rosae, Megoura viciae, Metopolophium dirhodum, Myzodes persicae, Myzus cerasi, Nilaparvata lugens, Pemphigus bursarius, Perkinsiella saccharicida, Phorodon humuli, Psylla mali, Psylla piri, Rhopalomyzus ascalonicus, Rhopalosiphum maidis, Sappaphis mala, Sappaphis mali, Schizaphis graminum, Schizoneura lanuginosa, Trialeurodes vaporariorum and Viteus vitifolii,    
      termites ( Isoptera ), e.g.  Calotermes flavicollis, Leucotermes flavipes, Reticulitermes lucifugus und Termes natalensis,    
      orthopterans (Orthoptera), e.g. Acheta domestica, Blatta orientalis, Blattella germanica, Forficula auricularia, Gryllotalpa gryllotalpa, Locusta migratoria, Melanoplus bivittatus, Melanoplus femur- rubrum, Melanoplus mexicanus, Melanoplus sanguinipes, Melanoplus spretus, Nomadacris septemfasciata, Periplaneta americana, Schistocerca americana, Schistocerca peregrina, Stauronotus maroccanus  and  Tachycines asynamorus,    
      Arachnoidea, such as arachnids ( Acarina ), e.g.  Amblyomma americanum, Amblyomma variegatum, Argas persicus, Boophilus annulatus, Boophilus decoloratus, Boophilus microplus, Brevipalpus phoenicis, Bryobia praetiosa, Dermacentor silvarum, Eotetranychus carpini, Eriophyes sheldoni, Hyalomma truncatum, Ixodes ricinus, Ixodes rubicundus, Ornithodorus moubata, Otobius megnini, Paratetranychus pilosus, Dermanyssus gallinae, Phyllocoptruta oleivora, Polyphagotarsonemus latus, Psoroptes ovis, Rhipicephalus appendiculatus, Rhipicephalus evertsi, Sarcoptes scabiei, Tetranychus cinnabarinus, Tetranychus kanzawai, Tetranychus pacificus, Tetranychus telarius and Tetranychus urticae,    
      Nematodes, especially plant parasitic nematodes such as root knot nematodes,  Meloidogyne hapla, Meloidogyne incognita, Meloidogyne javanica,  and other  Meloidogyne  species; cyst-forming nematodes,  Globodera rostochiensis  and other  Globodera  species;  Heterodera avenae, Heterodera glycines, Heterodera schachtii, Heterodera trifolii,  and other  Heterodera  species; Seed gall nematodes,  Anguina  species; Stem and foliar nematodes,  Aphelenchoides  species; Sting nematodes,  Belonolaimus longicaudatus  and other  Belonolaimus  species; Pine nematodes,  Bursaphelenchus xylophilus  and other  Bursaphelenchus  species; Ring nematodes,  Criconema  species,  Criconemella  species,  Criconemoides  species,  Mesocriconema  species; Stem and bulb nematodes,  Ditylenchus destructor, Ditylenchus dipsaci  and other  Ditylenchus  species; Awl nematodes,  Dolichodorus  species; Spiral nematodes,  Heliocotylenchus multicinctus  and other  Helicotylenchus  species; Sheath and sheathoid nematodes,  Hemicycliophora  species and  Hemicriconemoides  species;  Hirshmanniella  species; Lance nematodes,  Hoploaimus  species; false root-knot nematodes,  Nacobbus  species; Needle nematodes,  Longidorus elongatus  and other  Longidorus  species; Pin nematodes,  Paratylenchus  species; Lesion nematodes,  Pratylenchus neglectus, Pratylenchus penetrans, Pratylenchus curvitatus, Pratylenchus goodeyi  and other  Pratylenchus  species; Burrowing nematodes,  Radopholus similis  and other  Radopholus  species;  Reniform nematodes, Rotylenchus robustus  and other  Rotylenchus  species;  Scutellonema  species; Stubby root nematodes,  Trichodorus primitivus  and other  Trichodorus  species,  Paratrichodorus  species; Stunt nematodes,  Tylenchorhynchus claytoni, Tylenchorhynchus dubius  and other  Tylenchorhynchus  species; Citrus nematodes,  Tylenchulus  species; Dagger nematodes,  Xiphinema  species; and other plant parasitic nematode species.  
      The compounds of formula I are especially useful for the control of nematodes.  
      The compounds I also are suitable for use as fungicides. They exhibit activity against a broad spectrum of phytopathogenic fungi, in particular from the classes of the  Ascomycetes, Deuteromycetes, Phycomycetes  and  Basidiomycetes.  Some of them act systemically, and they can be employed in crop protection as foliar- and soil-acting fungicides.  
      They are especially important for controlling a large number of fungi on a variety of crop plants such as wheat, rye, barley, oats, rice, maize, grass, bananas, cotton, soya, coffee, sugar cane, grapevines, fruit species, ornamentals and vegetables such as cucumbers, beans, tomatoes, potatoes and cucurbits, and on the seeds of these plants. Specifically, they are suitable for controlling the following plant diseases:  
       Alternaria  species on vegetables and fruit,  Botrytis cinerea  (gray mold) on strawberries, vegetables, ornamentals and grapevines,  Cercospora arachidicola  on peanuts,  Erysiphe cichoracearum  and  Sphaerotheca fuliginea  on cucurbits,  Ezysiphe graminis  (powdery mildew) on cereals,  Fusarium  and  Verticillium  species on various plants,  Helminthosporium  species on cereals,  Mycosphaerella  species on bananas and peanuts,  Phytophthora infestans  on potatoes and tomatoes,  Plasmopara viticola  on grapevines,  Podosphaera leucotricha  on apples,  Pseudocercosporella herpotrichoides  on wheat and barley,  Pseudoperonospora  species on hops and cucumbers,  Puccinia  species on cereals,  Pyricularia oryzae  on rice,  Rhizoctonia  species on cotton, rice and lawns,  Septoria nodorum  on wheat,  Uncinula necator  on grapevines,  Ustilago  species on cereals and sugar cane, and Venturia species (scab) on apples and pears.  
      Moreover, the compounds I are suitable for controlling harmful fungi such as  Paecilomyces variotii  in the protection of materials (e.g. wood, paper, paint dispersions, fibers and fabrics) and in the protection of stored products.  
      The compounds I are applied by treating the fungi, or the plants, seeds, materials or the soil to be protected against fungal attack, with a fungicidally effective amount of the active ingredients. Application can be effected both before and after infection of the materials, plants or seeds by the fungi.  
      Compounds of formula I are suitable for use as herbicides. Depending upon the application method, compounds I and herbicidal compositions comprising them may be used in crops for the control of unwanted plants. Exemplary are the following crops:  
       Allium cepa, Ananas comosus, Arachis hypogaea, Asparagus officinalis, Beta vulgaris  spp.  altissima, Beta vulgaris  spp.  rapa, Brassica napus  var.  napus, Brassica napus  var.  napobrassica, Brassica rapa  var.  silvestris, Camellia sinensis, Carthamus tinctorius, Carya illinoinensis, Citrus limon, Citrus sinensis, Coffea arabica (Coffea canephora, Coffea liberica), Cucumis sativus, Cynodon dactylon, Daucus carota, Elaeis guineensis, Fragaria vesca, Glycine max, Gossypium hirsutum,  ( Gossypium arboreum, Gossypium herbaceum, Gossypium vitifolium ),  Helianthus annuus, Hevea brasiliensis, Hordeum vulgare, Humulus lupulus, Ipomoea batatas, Juglans regia, Lens culinaris, Linum usitatissimum, Lycopersicon lycopersicum, Malus  spp.,  Manihot esculenta, Medicago sativa, Musa  spp.,  Nicotiana tabacum  ( N. rustica ),  Olea europaea, Oxyza sativa, Phaseolus lunatus, Phaseolus vulgaris, Picea abies, Pinus  spp.,  Pisum sativum, Prunus avium, Prunus persica, Pyrus communis, Ribes sylvestre, Ricinus communis, Saccharum officinarum, Secale cereale, Solanum tuberosum, Sorghum bicolor  (s.  vulgare ),  Theobroma cacao, Trifolium pratense, Triticum aestivum, Triticum durum, Vicia faba, Vitis vinifera  und  Zea mays.    
      Compounds of formula I may also be used in crops that have acquired resistance against other herbicides.  
      For controlling animal pests, pesticidally active amounts of compounds of formula I are typically applied to the pests or to their food supply, habitat or breeding ground. For the protection of growing plants from attack or infestation by the pests, pesticidally active amounts of the compounds of formula I are typically applied to the foliage, stem or roots of the plants or to the soil or water in which they are growing.  
      The rate of application of active ingredient for controlling animal pests is from 0.01 to 100, preferably 0.1 to 3 kg/ha under field conditions.  
      The compounds I can be converted into the customary formulations, e.g. solutions, emulsions, suspensions, dusts, powders, pastes and granules. The use form depends on the particular purpose; in any case, it should guarantee a fine and uniform distribution of the compound according to the invention.  
      The formulations are prepared in a known manner, e.g. by extending the active ingredient with solvents and/or carriers, if desired using emulsifiers and dispersants, it also being possible to use other organic solvents as auxiliary solvents if water is used as the diluent. Auxiliaries which are suitable are essentially: solvents such as aromatics (e.g. xylene), chlorinated aromatics (e.g. chlorobenzenes), paraffins (e.g. mineral oil fractions), alcohols (e.g. methanol, butanol), ketones (e.g. cyclohexanone), amines (e.g. ethanolamine, dimethylformamide) and water; carriers such as ground natural minerals (e.g. kaolins, clays, talc, chalk) and ground synthetic minerals (e.g. highly-disperse silica, silicates); emulsifiers such as non-ionic and anionic emulsifiers (e.g. polyoxyethylene fatty alcohol ethers, alkylsulfonates and arylsulfonates) and dispersants such as lignin-sulfite waste liquors and methylcellulose.  
      Suitable surfactants are alkali metal, alkaline earth metal and ammonium salts of lignosulfonic acid, naphthalenesulfonic acid, phenolsulfonic acid, dibutylnaphthalenesulfonic acid, alkylarylsulfonates, alkyl sulfates, alkylsulfonates, fatty alcohol sulfates and fatty acids and their alkali metal and alkaline earth metal salts, salts of sulfated fatty alcohol glycol ether, condensates of sulfonated naphthalene and naphthalene derivatives with formaldehyde, condensates of naphthalene or of napthalenesulfonic acid with phenol or formaldehyde, polyoxyethylene octylphenyl ether, ethoxylated isooctylphenol, octylphenol, nonylphenol, alkylphenol polyglycol ethers, tributylphenyl polyglycol ethers, alkylaryl polyether alcohols, isotridecyl alcohol, fatty alcohol/ethylene oxide condensates, ethoxylated castor oil, polyoxyethylene alkyl ethers, ethoxylated polyoxypropylene, lauryl alcohol polyglycol ether acetal, sorbitol esters, lignin-sulfite waste liquors and methylcellulose.  
      Substances which are suitable for the preparation of directly sprayable solutions, emulsions, pastes or oil dispersions are mineral oil fractions of medium to high boiling point, such as kerosene or diesel oil, furthermore coal tar oils and oils of vegetable or animal origin, aliphatic, cyclic and aromatic hydrocarbons, e.g. benzene, toluene, xylene, paraffin, tetrahydronaphthalene, alkylated naphthalenes or their derivatives, methanol, ethanol, propanol, butanol, chloroform, carbon tetrachloride, cyclohexanol, cyclohexanone, chlorobenzene, isophorone, strongly polar solvents, e.g. dimethylformamide, dimethyl sulfoxide, N-methylpyrrolidone and water.  
      Powders, materials for scattering and dusts can be prepared by mixing or concomitantly grinding the active substances with a solid carrier.  
      Granules, e.g. coated granules, impregnated granules and homogeneous granules, can be prepared by binding the active ingredients to solid carriers. Examples of solid carriers are mineral earths, such as silicas, silica gels, silicates, talc, kaolin, attaclay, limestone, lime, chalk, bole, loess, clay, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground synthetic materials, fertilizers, e.g. ammonium sulfate, ammonium phosphate, ammonium nitrate, ureas, and products of vegetable origin, such as cereal meal, tree bark meal, wood meal and nutshell meal, cellulose powders and other solid carriers.  
      In general, the formulations comprise of from 0.01 to 95% by weight, preferably from 0.1 to 90% by weight, of the active ingredient. The active ingredients are employed in a purity of from 90% to 100%, preferably 95% to 100% (according to NMR spectrum).  
      The following are exemplary formulations: 
      I. 5 parts by weight of a compound according to the invention are mixed intimately with 95 parts by weight of finely divided kaolin. This gives a dust which comprises 5% by weight of the active ingredient.     II. 30 parts by weight of a compound according to the invention are mixed intimately with a mixture of 92 parts by weight of pulverulent silica gel and 8 parts by weight of paraffin oil which had been sprayed onto the surface of this silica gel. This gives a formulation of the active ingredient with good adhesion properties (comprises 23% by weight of active ingredient).     III. 10 parts by weight of a compound according to the invention are dissolved in a mixture composed of 90 parts by weight of xylene, 6 parts by weight of the adduct of 8 to 10 mol of ethylene oxide and 1 mol of oleic acid N-monoethanolamide, 2 parts by weight of calcium dodecylbenzenesulfonate and 2 parts by weight of the adduct of 40 mol of ethylene oxide and 1 mol of castor oil (comprises 9% by weight of active ingredient).     IV. 20 parts by weight of a compound according to the invention are dissolved in a mixture composed of 60 parts by weight of cyclohexanone, 30 parts by weight of isobutanol, 5 parts by weight of the adduct of 7 mol of ethylene oxide and 1 mol of isooctylphenol and 5 parts by weight of the adduct of 40 mol of ethylene oxide and 1 mol of castor oil (comprises 16% by weight of active ingredient).     V. 80 parts by weight of a compound according to the invention are mixed thoroughly with 3 parts by weight of sodium diisobutylnaphthalene-alpha-sulfonate, parts by weight of the sodium salt of a lignosulfonic acid from a sulfite waste liquor and 7 parts by weight of pulverulent silica gel, and the mixture is ground in a hammer mill (comprises 80% by weight of active ingredient).     VI. 90 parts by weight of a compound according to the invention are mixed with 10 parts by weight of N-methyl-α-pyrrolidone, which gives a solution which is suitable for use in the form of microdrops (comprises 90% by weight of active ingredient).     VII. 20 parts by weight of a compound according to the invention are dissolved in a mixture composed of 40 parts by weight of cyclohexanone, 30 parts by weight of isobutanol, 20 parts by weight of the adduct of 7 mol of ethylene oxide and 1 mol of isooctylphenol and 10 parts by weight of the adduct of 40 mol of ethylene oxide and I mol of castor oil. Pouring the solution into 100,000 parts by weight of water and finely distributing it therein gives an aqueous dispersion which comprises 0.02% by weight of the active ingredient.     VIII. 20 parts by weight of a compound according to the invention are mixed thoroughly with 3 parts by weight of sodium diisobutylnaphthalene-α-sulfonate, 17 parts by weight of the sodium salt of a lignosulfonic acid from a sulfite waste liquor and 60 parts by weight of pulverulent silica gel, and the mixture is ground in a hammer mill. Finely distributing the mixture in 20,000 parts by weight of water gives a spray mixture which comprises 0.1% by weight of the active ingredient.    

      The active ingredients can be used as such, in the form of their formulations or the use forms prepared therefrom, e.g. in the form of directly sprayable solutions, powders, suspensions or dispersions, emulsions, oil dispersions, pastes, dusts, materials for spreading, or granules, by means of spraying, atomizing, dusting, scattering or pouring. The use forms depend entirely on the intended purposes; in any case, this is intended to guarantee the finest possible distribution of the active ingredients according to the invention.  
      Aqueous use forms can be prepared from emulsion concentrates, pastes or wettable powders (sprayable powders, oil dispersions) by adding water. To prepare emulsions, pastes or oil dispersions, the substances as such or dissolved in an oil or solvent, can be homogenized in water by means of wetter, tackifier, dispersant or emulsifier. Alternatively, it is possible to prepare concentrates composed of active substance, wetter, tackifier, dispersant or emulsifier and, if appropriate, solvent or oil, and such concentrates are suitable for dilution with water.  
      The active ingredient concentrations in the ready-to-use products can be varied within substantial ranges. In general, they are from 0.0001 to 10%, preferably from 0.01 to 1%.  
      The active ingredients may also be used successfully in the ultra-low-volume process (ULV), it being possible to apply formulations comprising over 95% by weight of active ingredient, or even the active ingredient without additives.  
      Various types of oils, herbicides, fungicides, other pesticides, or bactericides may be added to the active ingredients, if appropriate also only immediately prior to use (tank mix). These agents can be admixed with the agents according to the invention in a weight ratio of 1:10 to 10:1.  
      In the use form as pesticides in crop protection, the compositions according to the invention can also be present together with other active ingredients, e.g. with herbicides, insecticides, growth regulators, fungicides or else with fertilizers. Mixing the compounds I or the compositions comprising them in the use form as pesticides with other pesticides frequently results in a broader pesticidal spectrum of action.  
      The following list of pesticides together with which the compounds according to the invention can be used, is intended to illustrate the possible combinations.  
      Organophosphates: Acephate, Azinphos-methyl, Chlorpyrifos, Chlorfenvinphos, Diazinon, Dichlorvos, Dicrotophos, Dimethoate, Disulfoton, Ethion, Fenitrothion, Fenthion, Isoxathion, Malathion, Methamidophos, Methidathion, Methyl-Parathion, Mevinphos, Monocrotophos, Oxydemeton-methyl, Paraoxon, Parathion, Phenthoate, Phosalone, Phosmet, Phosphamidon, Phorate, Phoxim, Pirimiphos-methyl, Profenofos, Prothiofos, Sulprophos, Triazophos, Trichlorfon;  
      Carbamates: Alanycarb, Benfuracarb, Carbaryl, Carbosulfan, Fenoxycarb, Furathiocarb, Indoxacarb, Methiocarb, Methomyl, Oxamyl, Pirimicarb, Propoxur, Thiodicarb, Triazamate;  
      Pyrethroids: Bifenthrin, Cyfluthrin, Cypermethrin, Deltamethrin, Esfenvalerate, Ethofenprox, Fenpropathrin, Fenvalerate, Cyhalothrin, Lambda-Cyhalothrin, Permethrin, Silafluofen, Tau-Fluvalinate, Tefluthrin, Tralomethrin, Zeta-Cypermethrin;  
      Arthropod growth regulators: a) chitin synthesis inhibitors: benzoylureas: Chlorfluazuron, Diflubenzuron, Flucycloxuron, Flufenoxuron, Hexaflumuron, Lufenuron, Novaluron, Teflubenzuron, Triflumuron; Buprofezin, Diofenolan, Hexythiazox, Etoxazole, Clofentazine; b) ecdysone antagonists: Halofenozide, Methoxyfenozide, Tebufenozide; c) juvenoids: Pyriproxyfen, Methoprene, Fenoxycarb; d) lipid biosynthesis inhibitors: Spirodiclofen;  
      Various: Abamectin, Acequinocyl, Amitraz, Azadirachtin, Bifenazate, Cartap, Chlorfenapyr, Chlordimeform, Cyromazine, Diafenthiuron, Dinetofuran, Diofenolan, Emamectin, Endosulfan, Fenazaquin, Fipronil, Formetanate, Formetanate, Hydrochloride, Hydramethylnon, Imidacloprid, Indoxacarb, Pyridaben, Pymetrozine, Spinosad, Sulfur, Tebufenpyrad, Thiamethoxam, and Thiocyclam.  
      This invention also provides a method for treating, curing, controlling, preventing and protecting warm-blooded animals, including humans, and fish against infestation and infection by helminths, acarids and arthropod endo- and ectoparasites which comprises orally, topically or parenterally administering or applying to said animals an anthelmintically, acaricidally or endo or ectoparasiticidally effective amount of compounds of formula I.  
      The above method is particularly useful for controlling and preventing helminth, acarid and arthropod endo- and ectoparasitic infestations and infections in warm-blooded animals such as cattle, sheep, swine, camels, deer, horses, poultry, fish, rabbits, goats, mink, fox, chinchillas, rabbits, dogs and cats as well as humans.  
      Compounds of formula I are especially useful in controlling helminths and nematodes. Examples for helminths are members of the class Trematoda, commonly known as flukes or flatworms, especially members of the genera  Fasciola, Fascioloides, Paramphistomum, Dicrocoelium, Eurytrema, Ophisthorchis, Fasciolopsis, Echinostoma  and  Paragonimus.  Nematodes which can be controlled by the formula I compounds include the genera  Haemonchus, Ostertagia, Cooperia, Oesphagastomum, Nematodirus, Dictyocaulus, Trichuris, Direofilaria, Ancyclostoma, Ascaris  and the like.  
      The formula I compounds of this invention also control endoparasitic arthropod infestations such as cattle grub and stomach bot. In addition, acarid and arthropod ectoparasitic infestations in warm-blooded animals and fish including biting lice, sucking lice, bot flies, biting flies, muscoid flies, myiasitic fly larvae, gnats, mosquitoes, fleas, mites, ticks, nasal bots, keds and chiggers may be controlled, prevented or eliminated by the compounds of this invention. Biting lice include members of  Mallophaga  such as  Bovicola bovis, Trichodectes canis  and  Damilina ovis.  Sucking lice include members of  Anoplura  such as  Haematopinus eurysternus, Haematopinus suis, Linognathus vituli  and  Solenopotes capillatus.  Biting flies include members of  Haematobia.  Ticks include  Boophilus, Rhipicephalus, Ixodes, Hyalomma, Amblyomma  and  Dermacentor.  The formula I compounds may also be used to control mites which are parasitic on warm-blooded mammals and poultry including mites of the orders  Acariformes  and  Parasitiformes.    
      For oral administration to warm-blooded animals, the formula I compounds may be formulated as animal feeds, animal feed premixes, animal feed concentrates, pills, solutions, pastes, suspensions, drenches, gels, tablets, boluses and capsules. In addition, the formula I compounds may be administered to the animals in their drinking water. For oral administration, the dosage form chosen should provide the animal with about 0.01 mg/kg to 100 mg/kg of animal body weight per day of the formula I compound.  
      Alternatively, the formula I compounds may be administered to animals parenterally, for example, by intraruminal, intramuscular, intravenous or subcutaneous injection. The formula I compounds may be dispersed or dissolved in a physiologically acceptable carrier for subcutaneous injection. Alternatively, the formula I compounds may be formulated into an implant for subcutaneous administration. In addition the formula I compound may be transdermally administered to animals. For parenteral administration, the dosage form chosen should provide the animal with about 0.01 mg/kg to 100 mg/kg of animal body weight per day of the formula I compound.  
      The formula I compounds may also be applied topically to the animals in the form of dips, dusts, powders, collars, medallions, sprays and pour-on formulations. For topical application, dips and sprays usually contain about 0.5 ppm to 5,000 ppm and preferably about 1 ppm to 3,000 ppm of the formula I compound. In addition, the formula I compounds may be formulated as ear tags for animals, particularly quadrupeds such as cattle and sheep.  
      The formula I compounds of this invention may also be used in combination or conjunction with one or more other parasiticidal compounds including anthelmintics, such as benzimidazoles, piperazine, levamisole, pyrantel, and praziquantel; endectocides such as avermectins, and milbemycins; ectoparasiticides such as arylpyrroles, organophosphates, and carbamates, gamabutyric acid inhibitors including fipronil, pyrethroids, spinosads and imidacloprid; insect growth regulators such as pyriproxyfen, and cyromazine; and chitin synthase inhibitors such as benzoylureas including flufenoxuron.  
      The formula I compounds may also be used in combination or conjunction with one or more compounds selected from piperonyl butoxide, N-octyl bicycloheptene dicarboximide, dipropyl pyridine-2,5-dicarboxylate and 1,5a,6,9,9a,9b-hexahydro-4a(4H)-dibenzo-furancarboxaldehyde to broaden the spectrum of activity.  
      The parasiticidal compositions of the present invention include a parasiticidally effective amount of a formula I compound of this invention or combinations thereof admixed with one or more physiologically tolerable inert, solid or liquid carriers known from veterinary medicinal practice for oral, percutaneous and topical administration. Such compositions may comprise further additives, such as stabilizers, anifoams, viscosity regulators, binders and tackifiers. Whereas commercial products will preferably be formulated as concentrates, the end user will normally employ dilute formulations. 
    
    
     SYNTHESIS EXAMPLES  
      With due modification of the starting compounds, the protocols shown in the synthesis examples below were used for obtaining further compounds I. The resulting compounds, together with physical data, are listed in Table I which follows.  
     Example 1  
     Preparation of 2-(5-Chloro-benzothiazol-2-yl-sulfanyl)-propionic Acid Ethyl Ester  
      A solution of 5-chloro-benzothiazol-2-thiol (1,4 g) in 50 ml acetonitrile was treated with potassium carbonate (1.0 g) and 2-bromo-propionic acid ethyl ester (1.25 g) for 3 hours at room temperature. The solvent was removed in vacuo and the residue redissolved in ethyl acetate and washed with water. The organic extract was dried over anhydrous sodium sulfate. Removal of solvent gave 2.1 g of the title compound as a light-brown oil.  1 H—NMR (δ [CDCl 3 ])=1.3 (m c ,3H), 1.7 (m c ,3H), 4.2 (m c , 2H), 4.7 (m c ,1H), 7.25 (d,1H), 7.65 (d,1H), 7.85 (s,1H).  
     Example 2  
     Preparation of 2-(5-Chloro-benzothiazol-2-yl-sulfanyl)-butyric Acid  
      A solution of 2-(5-chloro-benzothiazol-2-yl-sulfanyl)-butyric acid ethyl ester (1.62 g) in 40 ml of ethanol was treated with 40 ml of water and an aqueous solution of potassium hydroxide in water (85%, 0.36 g) for 14 hours at 25° C. Ethanol was removed in vacuo, the ressidue acidified with diluted hydrochloric acid and extracted with ethyl acetate. The organic extract was dried over anhydrous sodium sulfate. Removal of solvent gave 1.5 g of the title compound as a light-brown oil.  
       1 H-NMR (δ [d 6 -DMSO])=1.00 (t,3H), 2.00 (m c , 2H), 4.55 (t, 1H), 7.45 (d,1H), 7.95 (s,1H), 8.1 (d,1H).  
     Example 3  
     Preparation of 2-[4-(4-chlorophenyl)-thiazol-2-yl-sulfanyl]-hexanoic Acid 3,4,4-trifluoro-but-3-enyl Ester  
      A mixture of 2-[4-(4-chlorophenyl)-thiazol-2-yl-sulfanyl]-hexanoic acid (0.3 g), potassium carbonate (0.16 g) and 4-bromo-1,2,2-trifluorobut-1-ene (0.21 g) in 20 ml N,N-dimethylformamide was stirred at 40-45° C. for 4 hours. The reation mixture was poured into ice water and extracted with ethyl acetate. The organic extract was dried over anhydrous sodium sulfate and concentrated in vacuo to give 0.37 g of the title compound as a light-brown oil.  
       1 H-NMR (δ [CDCl 3 ])=0.9 (t,3H), 1.15-2.1 (m,6H), 2.6 (m c , 2H), 4.25-4.4 (m,3H), 7.35 (m c , 3H), 7.8 (d,2H).  
                   TABLE I                              (I.2)                                                                                               No   B   D   E   (R c ) q     q   R 1     R 2     m   n   p   Physical data:  1 H-NMR (δ [ppm])               I.2-1   CH   CH   O   6-Cl   1   H   H   0   0   4           I.2-2   CH   CH   S   —   O   H   H   0   0   4       I.2-3   CH   CH   S   6-CF 3     1   H   H   0   0   4       I.2-4   N   CH   S   6-CH 3     1   H   H   0   0   2       I.2-5   CH   CH   O   6-Cl   1   CH(CH 3 ) 2     H   0   0   2       I.2-6   CH   CH   S   —   O   H   H   0   0   2       I.2-7   CH   CH   O   —   O   H   H   0   0   2       I.2-8   CH   CH   S   —   O   CH 3     H   0   0   2       I.2-9   CH   CH   O   6-Cl   1   H   H   0   0   2       I.2-10   CH   CH   S   6-OCH 2 CH 3     1   H   H   0   0   2       I.2-11   CH   CH   S   —   O   OCH 2 CH 3     H   0   0   2   1.0(t), 2.10(m c ), 2.65(m c ), 4.30                                                   (t), 4.65(t), 7.25(t), 7.40(t),                                                   7.75(d), 7.85(d)       I.2-12   CH   CH   S   —   O   C 6 H 5     H   0   0   2       I.2-13   CH   CH   S   —   O   OCH(CH 3 ) 2     H   0   0   2       I.2-14   CH   CH   O   6-Cl   1   CH 3     H   0   0   2       I.2-15   CH   CH   S   5-Cl   1   H   H   0   0   2       I.2-16   CH   CH   NH   —   —   0   H   H   0   0   2       I.2-17   CH   N   S   —   —   0   H   H   0   0   2       I.2-18   N   CH   S   6-CH 3     1   CH 2 CH 3     H   0   0   2       I.2-19   N   CH   S   6-CH 3     1   CH(CH 3 ) 2     H   0   0   2       I.2-20   N   CH   O   —   H   H   0   0   2       I.2-21   N   CH   S   —   0   CH 3     H   0   0   2       I.2-22   N   CH   S   6-Br   1   H   H   0   0   2       I.2-23   CH   CH   S   6-OCH 2 CH 3     1   CH 3     H   0   0   2       I.2-24   N   CH   S   —   0   H   H   0   0   2       I.2-25   N   CH   S   —   0   CH(CH 3 ) 2     H   0   0   2       I.2-26   N   CH   S   —   0   F   H   0   0   2       I.2-27   CH   CH   S   —   0   CH 3     CH 3     0   0   2   1.75(s), 2.65(m c ), 4.30(t),                                                   7.35(t), 7.45(t), 7.75(d),                                                   7.90(d)       I.2-28   CH   CH   S   —   0   (CH 2 ) 3 CH 3     H   0   0   2   0.95(t), 1.30-1.55(m), 1.90-2.15                                                   (m), 2.60(m c ), 4.30(t), 4.65(t),                                                   7.30(t), 7.45(t), 7,75(d),                                                   7.85(d)       I.2-29   CH   CH   S   6-OCH 2 CH 3     1   (CH 2 ) 3 CH 3     H   0   0   2   0.90(t), 1.30-1.50(m), 1.85-2.10                                                   (m), 2.60(m c ), 4.05(q), 4.30(t),                                                   4.50(t); 6.95(d), 7.20(s),                                                   7.75(d)       I.2-30   CH   CH   S   6-OCH 2 CH 3     1   CH 3     CH 3     O   O   2   1.45(t), 1.70(s), 2.60(mj, 4.05                                                   (q), 4.30(t), 7.05(d), 7.25(s),                                                   7.80(d)       I.2-31   CH   CH   S   6-OCH 2 CH 3     1   CH 2 CH 3     H   0   0   2   1.15(t), 1.45(t), 1.95-2.2(m),                                                   4.05(q), 4.35(t), 4.5(t),                                                   7.0(d), 7.2(s), 7.75(d)       I.2-32   N   CH   S   6-CF 3     1   CH 2 CH 3     H   0   0   2   1.15(t), 2.0-2.25(m), 2.7(m c ),                                                   4.35(q), 4.95(t), 8.4(s), 8.9(s)       I.2-33   CH   CH   O   —   0   CH 3     H   0   0   2   1.75(d), 2.65(ni,~), 4.35(t), 4.65                                                   (q), 7.25(m c ), 7.45(d), 7.6(d)       I.2-34   CH   CH   O   —   0   CH 2 CH 3     CH 3     0   0   2   1.15(t), 2.10(m c ), 2,65(m c ), 4.3                                                   (t), 4.55(t), 7.25(m c ), 7.45(d),                                                   7.60 (d)       I.2-35   CH   CH   O   —   0   CH 3     CH 3     0   0   2   1.75(s), 2.65(m c ), 4.30(t),                                                   7.25(m c ), 7.45(d), 7.60(d)       I.2-36   CH   CH   O   —   0   (CH 2 ) 3 CH 3     H   0   0   2   0.95(t), 1.30-2.15(m), 2.65(m c )                                                   4.35(t), 4.55(t), 7.25(m c ), 7.45                                                   (d), 7.60(d)       I.2-37   CH   CH   O   —   0   CH(CH 3 ) 2     H   0   0   2   1.15(d), 2.40(m c ). 2.65(m c )                                                   4.35(t), 4.55(d), 7.25(m c ),                                                   7.45(d), 7.60(d)       I.2-38   CH   N   S   —   0   CH 3     H   0   0   2   1.75(d), 2.65(m c ). 4.35(t), 4.75                                                   (q), 7.35(m c ), 8.05(d), 8.45(d)       I.2-39   CH   N   S   —   0   CH 3     CH 3     0   0   2   1.75(s), 2.65(m c ), 4.30(t), 7.35                                                   (m c ), 8.05(d), 8.50(d)       I.2-40   CH   N   S   —   0   (CH 2 ) 3 CH 3     H   0   0   2   0.95(t), 1.25-2.15(m), 2.65(m c ),                                                   4.35(t), 4.75(t), 7.35(m c ), 8.0                                                   (d), 8.5(d)       I.2-41   N   CH   S   6-Cl   1   (CH 2 ) 3 CH 3     H   0   0   2   0.95(t), 1.25-2.15(m), 2.65(m c ),                                                   4.3(m c ), 4.95(t), 8.1(s),                                                   8.55(s)       I.2-42   N   CH   S   —   0   CH(CH 3 ) 2     H   0   0   2   1.15(d), 2.4(m c ), 2.65(m c ), 4.35                                                   (m c ), 4.75(d), 7.35(m c ),                                                   8.05(d), 8.45(d)       I.2-43   CH   CH   O   6-Cl   1   CH 2 CH 3     H   0   0   2   1.1(t), 2.05(m c ), 2.65(m c ), 4.35                                                   (t), 4.5(t), 7.25(d), 7.55(m c )       I.2-44   CH   CH   O   6-Cl   1   CH 3     CH 3     0   0   2   1.80(s), 2.65(m c ), 4.3(t), 7.25                                                   (d), 7.45(s), 7.55(d)       I.2-45   CH   CH   O   6-Cl   1   (CH 2 ) 3 CH 3     H   0   0   2   0.95(t), 1.25-2.15(m), 2.65(m c ),                                                   4.3(t), 4.5(t), 7.25(d), 7.5(m c )       I.2-46   CH   CH   S   6-OCH 2 CH 3     1   CH(CH 3 ) 2     H   0   0   2   1.15(m c ), 1.45(t), 2.35(m c ),                                                   2.65 (m c ), 4.05(q), 4.3(m c ),                                                   4.5(d), 7.0(d), 7.2(s), 7.75(d)       I.2-47   CH   CH   S   6-CF 3     1   H   H   0   0   2       I.2-48   CH   CH   O   5-CH 3     1   H   H   0   0   2       I.2-49   CH   CH   S   6-F   1   H   H   0   0   2       I.2-50   N   CH   S   6-CH 3     1   F   H   0   0   2       I.2-51   N   CH   S   6-CF 3     1   CH 3     H   0   0   2       I.2-52   CH   CH   S   6-OCF 3     1   H   H   0   0   2       I.2-53   N   CH   S   6-Br   1   CH 3     H   0   0   2   1.75(d), 2.65(m c ), 4.35(m c ),                                                   4.95(q), 8.25(s), 8.65(s)       I.2-54   N   CH   S   6-Br   1   CH 2 CH 3     H   0   0   2   1.1(t), 2.10(m c ), 2.65(m c ), 4.35                                                   (m c ), 4.90(t), 8.25(s), 8.65(s)       I.2-55   N   CH   S   6-Br   1   CH 3     CH 3     0   0   2   1.85(s), 2.65(m c ), 4.35(t), 8.25                                                   (s), 8.65(s)       I.2-56   CH   CH   O   5-CH 3     1   CH 3     H   0   0   2   1.75(d), 2.45(s), 2.65 (m c ), 4.35                                                   (t), 4.6(q), 7.05(d), 7.30(d),                                                   7.4(s)       I.2-57   CH   CH   O   5-CH 3     1   CH 2 CH 3     H   0   0   2   1.15(t), 2.1(m c ), 2.45(s), 2.65                                                   (m c ), 4.35(t), 4.55(t), 7.05(d),                                                   7.3(d), 7.4(s)       I.2-58   CH   CH   O   5-CH 3     1   CH 3     CH 3     0   0   2   1.8(s), 2.45(s), 2.65(m c ), 4.35                                                   (m c ), 7.1(d), 7.3(d), 7.4(s)       I.2-59   CH   CH   S   5-Cl   1   CH(CH 3 ) 2     H   0   0   2   1.15(d), 2.4(m c ), 2.65(m c ), 4.35                                                   (m c ), 4.65(d), 7.25(d) 7.65(d),                                                   7.85 (d)       I.2-60   N   CH   S   —   O   CH 2 CH 3     H   0   0   2   1.1(t), 2.1(m c ), 2.7(m c ),                                                   4.95(t), 7.25(m c ), 8.1(d),                                                   8.65(d)       I.2-61   N   CH   S   —   O   CH 3     CH 3     0   0   2   1.85(s), 2,65(m c ), 4.35(m c ),                                                   7.25(m c ), 8.1(d), 8.65(d)       I.2-62   N   CH   S   —   0   (CH 2 ) 3 CH 3     H   0   0   2   0.95(6), 1.3-2.2(m), 2.65(m c ),                                                   4.35(m c ), 4.95(t), 7.25(m c ),                                                   8.1(d), 8.65(d)       I.2-63   CH   CH   S   5-Cl   1   CH 3     H   0   0   2   1.75(d), 2.65(m c ), 4.3(t), 4.7                                                   (q), 7.25(d), 7.7(d), 7.85(s)       I.2-64   CH   CH   S   5-Cl   1   CH 2 CH 3     H   0   0   2   see example 3       I.2-65   CH   CH   S   5-Cl   1   CH 3     CH 3     0   0   2   1.75(s), 2.65(m c ), 4.35(t),                                                   7.3(d), 7.7(d), 7.85(s)       I.2-66   CH   CH   S   5-Cl   1   (CH 2 ) 3 CH 3     H   0   0   2   0.95(t), 1.3-2.1(m), 2.65(m c ),                                                   4.35(m c ), 4.65(t), 7.3(d),                                                   7.7(d), 7.85(s)       I.2-67   CH   CH   S   5-OCH 3     1   H   H   0   0   2   2.85(m c ), 3.55(t), 3.9(s), 6.95                                                   (d), 7.4(s), 7.6(d)       I.2-68   CH   CH   S   5-OCH 3     1   CH 3     H   0   0   2   1.7(d), 2.65 (m c ), 3.85(s),                                                   4.35(m c ), 4.7(q), 6.95(d),                                                   7.4(s), 7.6(d)       I.2-69   CH   CH   S   5-OCH 3     1   CH(CH 3 ) 2     H   0   0   2   1.15(m c ), 2.4(m c ), 2.65(m c ), 3.85                                                   (s), 4.35 (t), 4.6(d), 6.95(d),                                                   7.4(s), 7.6(d)       I.2-70   CH   N   NCH 3     —   0   H   H   0   0   2   2.85(m c ), 3.65(t), 3.75(s),                                                   7.2(m c ), 7.85(d), 8.25(d)       I.2-71   CH   CH   O   6-Cl   1   H   H   0   1   2   2.65(m c ), 3.0(t), 3.55(m c ), 4.35                                                   (t), 7.25(d), 7.45(s), 7.5(d)       I.2-72   CH   CH   S   0   H   H   0   2   2                                                       I.2-73   CH   CH   S   6-OCH 2 CH 3     1   H   H   0   2   2   1.45(t), 2.15(m c ), 2.5(t), 2.65                                                   (m c ), 3.35(t), 4.05(q), 4.25(t),                                                   7.0(d), 7.2(s), 7.75(d)       I.2-74   CH   CH   O   —   0   H   H   0   2   2   2.2(m c ), 2.5-2.7(m), 3.35(m c ),                                                   4.25(m c ), 7.25(m c ), 7.45(d), 7.6                                                   (d)       I.2-75   CH   CH   O   6-Cl   1   H   H   0   2   2   2.2(m c ), 2.55(m c ), 2.65(m c ), 3.35                                                   (m c ), 4.3(m c ), 7.25(d), 7.45(s),                                                   7.5(d)       I.2-76   CH   N   S   —   0   CH 3     H   2   0   2   1.8(d), 2.55(m c ), 4.3(m c ), 4.65                                                   (q), 7.65(m c ), 8.5(d), 8.8(d)       I.2-77   CH   N   S   —   0   CH 3     CH 3     2   0   2   1.8(s), 2.65(m c ), 4.3(t),                                                   7.6(dd), 8.5(d), 8.8(d)       I.2-78   CH   N   S   —   0   CH 3     CH 3     1   0   2   1.85(s), 2.65(m c ), 4.35(t), 7.55                                                   (dd), 8.15(d), 8.4(d)                  
 
     
       
         
           
               
               
             
               
                 TABLE II 
               
             
            
               
                   
               
               
                   
               
               
                   
                 (I.3) 
               
               
                 
                   
                     
                     
                         
                         
                     
                   
                 
               
               
                   
               
            
           
           
               
               
               
               
               
               
               
               
               
               
            
               
                 No. 
                 E′ 
                 (R c ) q   
                 q 
                 R 1   
                 R 2   
                 m 
                 n 
                 p 
                 Physical data:  1 H-NMR (δ [ppm]) 
               
               
                   
               
               
                 1.3-1 
                 S 
                 4-(p-F-C 6 H 4 ) 
                 1 
                 CH 2 CH 3   
                 CH 2 CH 3   
                 0 
                 0 
                 2 
                 1.0(m c ), 2.0(m c ), 2.6(m c ), 4.3 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 (m c ), 7.1(m c ), 7.4(s), 7.85(m c ) 
               
               
                 1.3-2 
                 S 
                 4-(p-F-C 6 H 4 ) 
                 1 
                 H 
                 H 
                 0 
                 0 
                 2 
                 2.65(m c ), 4.1(s), 4.35(m c ), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 7.1(m c ), 7.3(s), 7.85(m c ) 
               
               
                 1.3-3 
                 S 
                 4-(p-F-C 6 H 4 ) 
                 1 
                 CH 3   
                 H 
                 0 
                 0 
                 2 
                 1.7(d), 2.6(m c ), 4.3(m c ), 4.45 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 (q), 7.1(m c ), 7.35(s), 7.85(m c ) 
               
               
                 1.3-4 
                 S 
                 4-(p-F-C 6 H 4 ) 
                 1 
                 CH 3   
                 CH 3   
                 0 
                 0 
                 2 
                 1.7(s), 2.6(m c ), 4.25(t), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 7.1(m c ), 7.4(s), 7.85(m c ) 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
               
               
                 1.3-5 
                 S 
                 4-(p-F-C 6 H 4 ) 
                 1 
                 CH(CH 3 ) 2   
                 H 
                 0 
                 0 
                 2 
                 1.15(m c ), 2.3(m c ), 2.65(m c ), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 4.2-4.4(m), 7.1(m c ), 7.3(s), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 7.8 (m c ) 
               
               
                 1.3-6 
                 S 
                 4-(p-F-C 6 H 4 ) 
                 1 
                 (CH 2 ) 3 CH 3   
                 H 
                 0 
                 0 
                 2 
                 1.95(m c ), 1.2-2.1(m), 2.65(m c ), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 4.25-4.4 (m), 7.1(m c ), 7.35(s), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 7.85 (m c ) 
               
               
                 1.3-7 
                 S 
                 4-(p-F-C 6 H 4 ) 
                 1 
                 CH 2 CH 3   
                 H 
                 0 
                 0 
                 2 
                 1.15(t), 2.05(m c ), 2.6(m c ), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 4.2-4.45(m), 7.1(t), 7.3(s), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 7.85(m c ) 
               
               
                 1.3-8 
                 S 
                 4-(p-Cl-C 6 H 4 ) 
                 1 
                 CH 3   
                 CH 3   
                 0 
                 0 
                 2 
                 1.7(s), 2.55(m c ), 4.25(t), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 7.4(d), 7.5(s), 7.8(d) 
               
               
                 1.3-9 
                 S 
                 4-(p-C1-C 6 H 4 ) 
                 1 
                 CH 3   
                 H 
                 0 
                 0 
                 2 
                 1.7(s), 2.6(m c ), 4.3(m c ), 4.45 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 (q), 7.35(m c ), 7.8(d) 
               
               
                 1.3-10 
                 S 
                 4-(p-Cl-C 6 H 4 ) 
                 1 
                 (CH 2 ) 3 CH 3   
                 H 
                 0 
                 0 
                 2 
                 see example 4 
               
               
                 1.3-11 
                 S 
                 4-(p-Cl-C 6 H 4 ) 
                 1 
                 CH 2 CH 3   
                 H 
                 0 
                 0 
                 2 
                 1.15(t), 2.05(m c ), 2.65(m c ) 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 4.25-4.4(m), 7.35(m c ), 7.8(d) 
               
               
                 1.3-12 
                 S 
                 4-(o,p-Cl 2 -C 6 H 3 ) 
                 1 
                 CH 3   
                 H 
                 0 
                 0 
                 2 
                 1.65(m c ), 2.6(m c ). 4.2-4.5 (m), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 7.35(d), 7.5(s), 7.8(c), 7.95(d) 
               
               
                 1.3-13 
                 S 
                 4-(o,p-Cl 2 -C 6 H 3 ) 
                 1 
                 CH 3   
                 CH 3   
                 0 
                 0 
                 2 
                 1.7(s), 2.6(m c ), 4.3(m c ), 7.35 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 (d), 7.5(s), 7.9(m c ) 
               
               
                 1.3-14 
                 S 
                 4-(o,p-Cl 2 -C 6 H 3 ) 
                 1 
                 (CH 2 ) 3 CH 3   
                 H 
                 0 
                 0 
                 2 
                 0.9(t), 1.3-2.1(m), 2.6(m c ) 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 4.2-4.4(m), 7.3(d), 7.5(s), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 7.8(s), 7.95(d) 
               
               
                 1.3-15 
                 S 
                 4-(o,p-Cl 2 -C 6 H 3 ) 
                 1 
                 CH(CH 3 ) 2   
                 H 
                 0 
                 0 
                 2 
                 1.1(dd), 2.3(m c ), 2.65(m c ), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 4.2-4.4(m), 7.3(d), 7.5(s), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 7.8(s), 7.95(d) 
               
               
                 1.3-16 
                 S 
                 4-(p-Cl-C 6 H 4 ) 
                 1 
                 CH(CH 3 ) 2   
                 H 
                 0 
                 0 
                 2 
                 1.15(dd), 2.35(m c ), 2.65(m c ), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 4.2-4.4(m), 7.35(m c ) 7.8(d) 
               
               
                 1.3-17 
                 S 
                 4-(C 6 H 5 ) 
                 1 
                 CH 3   
                 CH 3   
                 0 
                 0 
                 2 
                 1.7(s), 2.6(m c ), 4.3(t), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 7.3-7.5(m), 7.85(d) 
               
               
                 1.3-18 
                 S 
                 4-(C 6 H 5 ) 
                 1 
                 (CH 2 ) 3 CH 3   
                 H 
                 0 
                 0 
                 2 
                 0.9(t), 1.3-2.1(m), 2.6(m c ), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 4.2-4.45(m), 7.25-7.45(m), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 7.85(d) 
               
               
                 1.3-19 
                 S 
                 5-(C 6 H 5 ) 
                 1 
                 CH(CH 3 ) 2   
                 H 
                 0 
                 0 
                 2 
                 1.15(dd), 2.35(m c ), 2.65(m c ), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 4.2-4.4(m), 7.25-7.45(m), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 7.85(d) 
               
               
                 1.3-20 
                 O 
                 4-(C 6 H 5 ),5-(C 6 H 5 ) 
                 2 
                 H 
                 H 
                 0 
                 0 
                 2 
                 2.65(m c ), 4.05(s), 4.35(t), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 7.25-7.60(m) 
               
               
                 1.3-21 
                 O 
                 4-(C 6 H 5 ),5-(C 6 H 5 ) 
                 2 
                 CH 2 CH 3   
                 H 
                 0 
                 0 
                 2 
                 1.15(t), 2.1(m c ), 2.65(m c ), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 4.3(m c ), 7.25-7.6(m) 
               
               
                 1.3-22 
                 O 
                 4-(C 6 H 5 ),5-(C 6 H 5 ) 
                 2 
                 CH 3   
                 H 
                 0 
                 0 
                 2 
                 1.75(d), 2.65(m c ), 4.25-4.5 (m), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 7.25-7.55(m) 
               
               
                 1.3-23 
                 O 
                 4-(C 6 H 5 ),5-(C 6 H 5 ) 
                 2 
                 CH 3   
                 CH 3   
                 0 
                 0 
                 2 
                 1.75(s), 2.65(m c ), 4.3(t), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 7.25-7.6(m) 
               
               
                 1.3-24 
                 O 
                 4-(C 6 H 5 ),5-(C 6 H 5 ) 
                 2 
                 CH(CH 3 ) 2   
                 H 
                 0 
                 0 
                 2 
                 1.15(dd), 2.35(m c ), 2.65(m c ), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 4.25-4.45(m), 7.25-7.6(m) 
               
               
                 1.3-25 
                 O 
                 4-(C 6 H 5 ),5-(C 6 H 5 ) 
                 2 
                 (CH 2 ) 3 CH 3   
                 H 
                 0 
                 0 
                 2 
                 0.9(t), 1.3-2.1(m), 2.65(m c ), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 4.25-4.45(m,), 7.25-7.6(m) 
               
               
                 1.3-26 
                 S 
                 4-(C 6 H 5 ) 
                 1 
                 H 
                 H 
                 0 
                 0 
                 2 
               
               
                 1.3-27 
                 S 
                 4-(C 6 H 5 ) 
                 1 
                 CH 3   
                 H 
                 0 
                 0 
                 2 
               
               
                 1.3-28 
                 S 
                 4-(C 6 H 5 ) 
                 1 
                 CH 2 CH 3   
                 H 
                 0 
                 0 
                 2 
               
               
                 1.3-29 
                 S 
                 4-(C 6 H 5 ) 
                 1 
                 H 
                 H 
                 0 
                 1 
                 2 
                 2.65(m c ), 2.95(t), 3.55(t), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 4.35(t), 7.3-7.55(m), 7.85(d) 
               
               
                 1.3-30 
                 S 
                 4-(C 6 H 5 ) 
                 1 
                 H 
                 H 
                 0 
                 2 
                 2 
                 2.15(m c ), 2.5-2.7(m), 3.35(t), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 4.25(t), 7.25-7.45(m), 7.85(d) 
               
               
                 1.3-31 
                 S 
                 4-(p-F-C 6 H 4 ) 
                 1 
                 H 
                 H 
                 2 
                 0 
                 2 
                 2.65(m c ), 4.3(t), 4.55(s), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 7.15(t), 7.8(s), 7.95(m c ) 
               
               
                 1.3-32 
                 S 
                 4-(p-F-C 6 H 4 ) 
                 1 
                 CH 3   
                 H 
                 2 
                 0 
                 2 
                 1.8(d), 2.65(m c ). 4.3(m c ), 4.55 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 (q), 7.15(m c ). 7.8(s), 7.95(m c ) 
               
               
                 1.3-33 
                 S 
                 4-(p-F-C 6 H 4 ) 
                 1 
                 CH 2 CH 3   
                 H 
                 1 
                 0 
                 2 
                 1.1(m c ). 2.15(m c ), 2.6(m c ), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 3.85-4.4(m), 7.1(m c ), 7.75(d), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 7.85 (m c ) 
               
               
                 1.3-34 
                 S 
                 4-(p-F-C 6 H 4 ) 
                 1 
                 CH 3   
                 CH 3   
                 1 
                 0 
                 2 
                 1.2(s), 1.7(s), 2.55(m c ) 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 4.35(m c ), 7.1(m c ), 7.7(s), 
               
               
                 1.3-35 
                 S 
                 4-(p-F-C 6 H 4 ) 
                 1 
                 (CH 2 ) 3 CH 3   
                 H 
                 1 
                 0 
                 2 
                 0.9(m c ), 1.15-2.2(m), 2.6(m c ) 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 3.9-4.4(m), 7.15(m c ), 7.7(d), 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 7.85(m c ) 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
               
             
               
                 TABLE III 
               
             
            
               
                   
               
               
                   
               
               
                   
                 (I.4) 
               
               
                 
                   
                     
                     
                         
                         
                     
                   
                 
               
               
                   
               
            
           
           
               
               
               
               
               
               
               
            
               
                 No. 
                 E 
                 R c   
                 R 1   
                 R 2   
                 p 
                 Physical data:  1 NMR (δ [ppm]) 
               
               
                   
               
               
                 1.4-1 
                 O 
                 p-F-C 6 H 4   
                 H 
                 H 
                 2 
                 2.7(m c ), 4.15(s), 4.4(t), 7.2(m c ), 8.0(m c ) 
               
               
                 1.4-2 
                 O 
                 p-CH 3 -C 6 H 4   
                 H 
                 H 
                 2 
                 2.4(s), 2.65(m c ), 4.15(s), 4.35(t), 7.3(m c ), 
               
               
                   
                   
                   
                   
                   
                   
                 7.9(m c ) 
               
               
                 1.4-3 
                 O 
                 p-F-C 6 H 4   
                 CH 3   
                 H 
                 2 
                 1.75(d), 2.65(m c ), 4.25-4.55(m), 7.2(m c ), 8.0(m c ) 
               
               
                 1.4-4 
                 O 
                 p-F-C 6 H 4   
                 CH(CH 3 ) 2   
                 H 
                 2 
                 1.15(m c ), 2,4(m c ), 2.65(m c ). 4.3-4.45(m), 
               
               
                   
                   
                   
                   
                   
                   
                 7.2(m c ), 8.0(m c ) 
               
               
                 1.4-5 
                 S 
                 CH 3   
                 H 
                 H 
                 2 
                 2.65(m c ), 2.75(s), 4.15(s), 4.35(t) 
               
               
                 1.4-6 
                 S 
                 CH 3   
                 CH 3   
                 H 
                 2 
                 1.7(d), 2.65(m c ). 2.75(s), 4.35(m c ), 4.55(q) 
               
               
                 1.4-7 
                 S 
                 CH 3   
                 CH(CH 3 ) 2   
                 H 
                 2 
                 1.15(dd), 2.35(m c ), 2.65(m c ), 2.75(s), 4.3(m c ), 
               
               
                   
                   
                   
                   
                   
                   
                 4.45(d) 
               
               
                 1.4-8 
                 O 
                 p-F-C 6 H 4   
                 CH 2 CH 3   
                 H 
                 2 
                 1.15(t), 2.15(m c ), 2.65(m c ), 4.3-4.5(m), 7.25 
               
               
                   
                   
                   
                   
                   
                   
                 (m c ), 8.0(m c ) 
               
               
                 1.4-9 
                 S 
                 CH 3   
                 CH 2 CH 3   
                 H 
                 2 
                 1.1(t), 2.05(m c ). 2.65(m c ), 2.75(s), 4.25-4.5(m) 
               
               
                 1.4-10 
                 S 
                 CH 3   
                 CH 3   
                 H 
                 2 
                 1.75(d), 2.65(m c ). 4.35(m c ), 4.75(q), 9.05(s) 
               
               
                 1.4-11 
                 S 
                 CH 3   
                 H 
                 H 
                 2 
                 2.65(m c ), 4.2(s), 4.35(m c ), 9.05(s) 
               
               
                   
               
            
           
         
       
     
      Examples of Action Against Animal Pests  
      The action of the compounds of the formula I against pests was demonstrated by the following experiments:  
      The active compounds were formulated 
      a. for testing the activity against nematodes as an about 0.05% w/v strength solution in a carrier of 5% by volume of acetone and 0.05% by volume Tween 20 (Polyoxyethylene-(20)-sorbitan monolaurate) in water, which was then diluted with 5% acetone in water and 0.05% Tween 20 in water to achieve the desired concentrations for drenching.     b. for testing the activity against insects and arachnids as a 10.000 ppm solution in a mixture of 35% acetone and water, which was diluted with water, if needed.    

      After the experiments were completed, in each case the lowest concentration was determined at which the compound still caused an 80 to 100% inhibition or mortality in comparison with untreated controls (limit or minimal concentration).  
      Activity Against Nematode Plant Diseases  
      Soybean cyst nematode (SCN),  Heterodera glycines  Tomato root knot nematode (RKN),  Meloidogyne incognita    
      Silty loam soil in individual pots with 1-week-old tomato transplants (cultivar Bonny Best) and soybean transplants (cultivar Hutcheson) were drenched with the test solution of the active ingredient. Aqueous suspensions of J2 nematode larvae and  Meloidogyne incognita  in the case of tomatoes and  Heterodera glycines  in the case of soybeans were drenched on the soil surface. Plants were kept one day in a moist infection chamber at 26° C. then moved into the greenhouse and maintained with bottom watering until harvested for evaluation. The tests were replicated 3 times for each disease.  
      In the case of root knot nematode on tomatoes, plants were harvested two weeks after treatment and inoculation. Roots were washed free of soil and the number of root knot galls on each root system was visually examined and compared for treated and plants that were only treated with the acetone/Tween 20 carrier.  
      In the case of soybean cyst nematode on soybeans, plants were harvested four weeks after treatment and inoculation. Roots were washed free of soil and the number of cysts per root-mass was visually examined and compared for treated and plants that were only treated with the acetone/Tween 20 carrier.  
      In this test, tomato plants which had been treated with 0.6 kg/ha of the compounds I.2-11, I.2-29, I.2-31, I.2.-32, I.2-33, I.2-37, I.3.-2, I.3.-4, I.3-7 and I.3-11 showed a reduction in root knot galling of 100% compared to plants treated with the acetone/Tween 20 carrier.  
      Activity Against Insects and Arachnids  
       Spodoptera eridania,  2nd Instar Larvae, Southern Armyworm (SAW)  
      Leaves of two lima bean plants contained in pots at BBCH stage 11 were dipped in the test solution, allowed to dry and then placed in plastic bags with holes punched for ventilation. Ten 2nd instar larvae were introduced. After 4 days, mortality, reduced feeding, or any interference with normal growth was examined visually.  
       Diabrotica virgifera virgifera Leconte,  2nd Instar Western Corn Rootworm (WCR)  
      1 ml of the test solution was pipetted onto 1 ccm 3  of talc in a 30 ml screw-top glass jar so as to provide 1.25 mg of active ingredient per jar (corresponding to about 50 kg/ha). The dried talc was loosened, and 1 ccm 3  of millet seed as food for the insects and 25 ml of moist soil were added to each jar and the contents were mixed mechanically. 10 2nd instar rootworms were added to each jar and the jars are loosely capped to allow air exchange for the larvae. The treatments were held for 5 days when mortality counts were made. Missing larvae were presumed dead, since they decompose rapidly and cannot be found.  
       Tetranychus urticae  (OP-Resistant Strain), 2-Spotted Spider Mite (TSM)  
      Sieva lima bean plants with primary leaves expanded to 7-8 cm were infested by placing on each a small piece from an infested leaf (with about 100 mites) taken from the main colony. This was done at about 2 hours before treatment to allow the mites to move over to the test plant to lay eggs. The piece of leaf used to transfer the mites was removed. The newly-infested plants were dipped in the test solution and allowed to dry. After 2 days, one leaf is removed and mortality counts are made.  
       Aphis gossypii,  Cotton Aphid (CA)  
      Cotton plants at the cotyledon stage (one plant per pot) were infested by placing a heavily infested leaf from the main colony on top of each cotyledon. The aphids were allowed to transfer to the host plant overnight, and the leaf used to transfer the aphids was removed. The cotyledons were dipped in the test solution and allowed to dry. After 5 days, mortality counts were made.  
       Spodoptera eridania,  Eggs-Southern Armyworm and  Diabrotica undecimpunctata howardi,  Eggs-Southern Corn Rootworm (SAW-Eggs) and (SCR-Eggs)  
      Wells containing artificial diet were treated with the test solutions and dried. The appropriate insect eggs were then placed in the wells which were covered with vented covers. After 7 days, mortality counts were made.  
      In this test, Tetranychus urticae which had been treated with 100 ppm of compound I.2-6 showed a kill rate of over 75% whereas untreated pests showed a rate of 0%.