Patent Publication Number: US-6713436-B1

Title: 1-cycloalkylpyrazolyl-benzoyl derivatives

Description:
This application is a 371 of PCT/EP99/09342 filed Dec. 1, 1999. 
    
    
     The present invention relates to 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I                    
     where: 
     X is O, NR 6  or CR 7 R 8 ; 
     Y is O, S, NR 9  or CR 10 R 11 ; 
     R 1  is nitro, halogen, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy, C 1 -C 4 -haloalkoxy, C 1 -C 4 -alkylthio, C 1 -C 4 -haloalkylthio, C 1 -C 4 -alkylsulfonyl or C 1 -C 4 -haloalkylsulfonyl; 
     R 2 ,R 3 ,R 7 ,R 8 ,R 10 ,R 11  are hydrogen, C 1 -C 4 -alkyl or C 1 -C 4 -haloalkyl; 
     or 
     R 3  and R 6  or R 3  and R 8  or R 3  and R 9  or R 3  and R 11  together form a bond; 
     R 4  is halogen, nitro, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy, C 1 -C 4 -haloalkoxy, C 1 -C 4 -alkylthio, C 1 -C 4 -haloalkylthio, C 1 -C 4 -alkylsulfonyl or C 1 -C 4 -haloalkylsulfonyl; 
     R 5  is hydrogen, halogen or C 1 -C 4 -alkyl; 
     R 6 ,R 9  are hydrogen or C 1 -C 6 -alkyl; 
     R 12  is hydroxyl, C 1 -C 6 -alkoxy, C 3 -C 6 -alkenyloxy, C 1 -C 6 -alkylsulfonyloxy, C 1 -C 6 -alkylcarbonyloxy, phenylsulfonyloxy or phenylcarbonyloxy, where the phenyl radical of the two last-mentioned substituents may be partially or fully halogenated and/or may carry one to three of the following groups: nitro, cyano, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy or C 1 -C 4 -haloalkoxy; 
     R 13  is a cyclic ring system containing 3 to 14 ring atoms which may be partially or fully halogenated and/or may carry one to three of the following groups: C 1 -C 4 -alkyl, C 1 -C 4 -alkoxy, C 1 -C 4 -haloalkyl or C 1 -C 4 -haloalkoxy; 
     R 14  is hydrogen or C 1 -C 4 -alkyl; 
     and their agriculturally useful salts. 
     Moreover, the invention relates to processes for preparing compounds of the formula I, to compositions comprising them and to the use of these derivatives or of compositions comprising them for controlling harmful plants. 
     Cycloalkyl-substituted pyrazolylbenzoyl derivatives which are substituted in the 3-position of the benzoyl radical by an N-bonded heterocycle or by phenyl are disclosed in the literature, for example in WO 98/42678 and WO 98/52926. 
     However, the herbicidal properties of the prior art compounds and their compatibility with crop plants may not be entirely satisfactory. 
     It is an object of the present invention to provide novel, in particular herbicidally active, compounds having improved properties. 
     We have found that this object is achieved by the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I and their herbicidal action. 
     Furthermore, we have found herbicidal compositions which comprise the compounds I and have very good herbicidal action. Moreover, we have found processes for preparing these compositions and methods for controlling undesirable vegetation using the compounds I. 
     Depending on the substitution pattern, the compounds of the formula I may contain one or more chiral centers, in which case they are present as enantiomers or mixtures of diastereomers. The invention provides both the pure enantiomers or diastereomers and their mixtures. 
     The compounds of the formula I can also be present in the form of their agriculturally useful salts, the kind of salt usually being immaterial. In general, the salts of those cations or the acid addition salts of those acids are suitable whose cations and anions, respectively, do not adversely affect the herbicidal action of the compounds I. 
     Suitable cations are, in particular, ions of the alkali metals, preferably lithium, sodium and potassium, of the alkaline earth metals, preferably calcium and magnesium, and of the transition metals, preferably manganese, copper, zinc and iron, and also ammonium, where, if desired, one to four hydrogen atoms may be replaced here by C 1 -C 4 -alkyl, hydroxy-C 1 -C 4 -alkyl, C 1 -C 4 -alkoxy-C 1 -C 4 -alkyl, hydroxy-C 1 -C 4 -alkoxy-C 1 -C 4 -alkyl, phenyl or benzyl, preferably ammonium, dimethylassonium, diisopropylammonium, tetramethylammonium, tetrabutylammonium, 2-(2-hydroxyeth-1-oxy)eth-1-ylammonium, di(2-hydroxyeth-1-yl)ammonium, trimethylbenzylammonium, furthermore phosphonium ions, sulfonium ions, preferably tri(C 1 -C 4 -alkyl)sulfonium, and sulfoxonium ions, preferably tri(C 1 -C 4 -alkyl)sulfoxonium. 
     Anions of useful acid addition salts are primarily chloride, bromide, fluoride, hydrogen sulfate, sulfate, dihydrogen phosphate, hydrogen phosphate, nitrate, bicarbonate, carbonate, hexafluorosilicate, hexafluorophosphate, benzoate and the anions of C 1 -C 4 -alkanoic acids, preferably formate, acetate, propionate and butyrate. 
     The organic molecular moieties mentioned for the substituents R 1 -R 12  or as radicals on phenyl rings are collective terms for individual enumerations of the individual group members. All hydrocarbon chains, i.e. all alkyl, alkylcarbonyl, haloalkyl, alkoxy, haloalkoxy, alkylcarbonyloxy, alkylsulfonyloxy, alkylthio, haloalkylthio, alkylsulfonyl, haloalkylsulfonyl, alkenyl and alkenyloxy moieties can be straight-chain or branched. Unless indicated otherwise, halogenated substituents preferably carry one to five identical or different halogen atoms. The term halogen represents in each case fluorine, chlorine, bromine or iodine. 
     Examples of other meanings are: 
     C 1 -C 4 -alkyl, and the alkyl moieties of C 1 -C 4 -alkylcarbonyl and C 1 -C 4 -alkylcarbonyloxy: for example methyl, ethyl, propyl, 1-methylethyl, butyl, 1-methylpropyl, 2-methylpropyl and 1,1-dimethylethyl; 
     C 1 -C 6 -alkyl, and the alkyl moieties of C 1 -C 6 -alkylcarbonyl and C 1 -C 6 -alkylcarbonyloxy: C 1 -C 4 -alkyl as mentioned above, and also, for example, pentyl, 1-methylbutyl, 2-methylbutyl, 3-methylbutyl, 2,2-dimethylpropyl, 1-ethylpropyl, hexyl, 1,1-dimethylpropyl, 1,2-dimethylpropyl, 1-methylpentyl, 2-methylpentyl, 3-methylpentyl, 4-methylpentyl, 1,1-dimethylbutyl, 1,2-dimethylbutyl, 1,3-dimethylbutyl, 2,2-dimethylbutyl, 2,3-dimethylbutyl, 3,3-dimethylbutyl, 1-ethylbutyl, 2-ethylbutyl, 1,1,2-trimethylpropyl, 1-ethyl-1-methylpropyl and 1-ethyl-3-methylpropyl; 
     C 1 -C 4 -haloalkyl: a C 1 -C 4 -alkyl radical as mentioned above which is partially or fully substituted by fluorine, chlorine, bromine and/or iodine, i.e., for example, chloromethyl, dichloromethyl, trichloromethyl, fluoromethyl, difluoromethyl, trifluoromethyl, chlorofluoramethyl, dichlorofluoromethyl, chlorodifluoromethyl, bromoethyl, iodomethyl, 2-fluoroethyl, 2-chloroethyl, 2-bromoethyl, 2-iodoethyl, 2,2-difluoroethyl, 2,2,2-trifluoroethyl, 2-chloro-2-fluoroethyl, 2-chloro-2,2-difluoroethyl, 2,2-dichloro-2-fluoroethyl, 2,2,2-trichloroethyl, pentafluoroethyl, 2-fluoropropyl, 3-fluoropropyl, 2,2-difluoropropyl, 2,3-difluoropropyl, 2-chloropropyl, 3-chloropropyl, 2,3-dichloropropyl, 2-bromopropyl, 3-bromopropyl, 3,3,3-trifluoropropyl, 3,3,3-trichloropropyl, 2,2,3,3,3-pentafluoropropyl, heptafluoropropyl, 1-(fluoromethyl)-2-fluoroethyl, 1-(chloromethyl)-2-chloroethyl, 1-(bromomethyl)-2-bromoethyl, 4-fluorobutyl, 4-chlorobutyl, 4-bromobutyl and nonafluorobutyl; 
     C 1 -C 4 -alkoxy: for example methoxy, ethoxy, propoxy, 1-methylethoxy, butoxy, 1-methylpropoxy, 2-methylpropoxy and 1,1-dimethylethoxy; 
     C 1 -C 6 -alkoxy: C 1 -C 4 -alkoxy as mentioned above, and also, for example, pentoxy, 1-methylbutoxy, 2-methylbutoxy, 3-methylbutoxy, 1,1-dimethylpropoxy, 1,2-dimethylpropoxy, 2,2-dimethylpropoxy, 1-ethylpropoxy, hexoxy, 1-methylpentoxy, 2-methylpentoxy, 3-methylpentoxy, 4-methylpentoxy, 1,1-dimethylbutoxy, 1,2-dimethylbutoxy, 1,3-dimethylbutoxy, 2,2-dimethylbutoxy, 2,3-dimethylbutoxy, 3,3-dimethylbutoxy, 1-ethylbutoxy, 2-ethylbutoxy, 1,1,2-trimethylpropoxy, 1,2,2-trimethylpropoxy, 1-ethyl-1-methylpropoxy and 1-ethyl-2-methylpropoxy; 
     C 1 -C 4 -haloalkoxy: a C 1 -C 4 -alkoxy radical as mentioned above which is partially or fully substituted by fluorine, chlorine, bromine and/or iodine, i.e., for example, fluoromethoxy, difluoromethoxy, trifluoromethoxy, chlorodifluoromethoxy, bromodifluoromethoxy, 2-fluoroethoxy, 2-chloroethoxy, 2-bromoethoxy, 2-iodoethoxy, 2,2-difluoroethoxy, 2,2,2-trifluoroethoxy, 2-chloro-2-fluoroethoxy, 2-chloro-2,2-difluoroethoxy, 2,2-dichloro-2-fluoroethoxy, 2,2,2-trichloroethoxy, pentafluoroethoxy, 2-fluoropropoxy, 3-fluoropropoxy, 2-chloropropoxy, 3-chloropropoxy, 2-bromopropoxy, 3-bromopropoxy, 2,2-difluoropropoxy, 2,3-difluoropropoxy, 2,3-dichloropropoxy, 3,3,3-trifluoropropoxy, 3,3,3-trichloropropoxy, 2,2,3,3,3-pentafluoropropoxy, heptafluoropropoxy, 1-(fluoromethyl)-2-fluoroethoxy, 1-(chloromethyl)-2-chloroethoxy, 1-(bromomethyl)-2-bromoethoxy, 4-fluorobutoxy, 4-chlorobutoxy, 4-bromobutoxy and nonafluorobutoxy; 
     C 1 -C 4 -alkylthio: for example methylthio, ethylthio, propylthio, 1-methylethylthio, butylthio, 1-methylpropylthio, 2-methylpropylthio and 1,1-dimethylethylthio; 
     C 1 -C 4 -haloalkylthio: a C 1 -C 4 -alkylthio radical as mentioned above which is partially or fully substituted by fluorine, chlorine, bromine and/or iodine, i.e., for example, fluoromethylthio, difluoromethylthio, trifluoromethylthio, chlorodifluoromethylthio, bromodifluoromethylthio, 2-fluoroethylthio, 2-chloroethylthio, 2-bromoethylthio, 2-iodoethylthio, 2,2-difluoroethylthio, 2,2,2-trifluoroethylthio, 2,2,2-trichloroethylthio, 2-chloro-2-fluoroethylthio, 2-chloro-2,2-difluoroethylthio, 2,2-dichloro-2-fluoroethylthio, pentafluoroethylthio, 2-fluoropropylthio, 3-fluoropropylthio, 2-chloropropylthio, 3-chloropropylthio, 2-bromopropylthio, 3-bromopropylthio, 2,2-difluoropropylthio, 2,3-difluoropropylthio, 2,3-dichloropropylthio, 3,3,3-trifluoropropylthio, 3,3,3-trichloropropylthio, 2,2,3,3,3-pentafluoropropylthio, heptafluoropropylthio, 1-(fluoromethyl)-2-fluoroethylthio, 1-(chloromethyl)-2-chloroethylthio, 1-(bromomethyl)-2-bromoethylthio, 4-fluorobutylthio, 4-chlorobutylthio, 4-bromobutylthio and nonafluorobutylthio; 
     C 1 -C 4 -alkylsulfonyl (C 1 -C 4 -alkyl-S(═O) 2 -), and the alkylsulfonyl moieties of C 1 -C 4 -alkylsulfonyloxy: for example methylsulfonyl, ethylsulfonyl, propylsulfonyl, 1-methylethylsulfonyl, butylsulfonyl, 1-methylpropylsulfonyl, 2-methylpropylsulfonyl and 1,1-dimethylethylsulfonyl; 
     C 1 -C 6 -alkylsulfonyl, and the alkylsulfonyl moieties of C 1 -C 6 -alkylsulfonyloxy: a C 1 -C 4 -alkylsulfonyl radical as mentioned above, and also, for example, pentylsulfonyl, 1-methylbutylsulfonyl, 2-methylbutylsulfonyl, 3-methylbutylsulfonyl, 1,1-dimethylpropylsulfonyl, 1,2-dimethylpropylsulfonyl, 2,2-dimethylpropylsulfonyl, 1-ethylpropylsulfonyl, hexylsulfonyl, 1-methylpentylsulfonyl, 2-methylpentylsulfonyl, 3-methylpentylsulfonyl, 4-methylpentylsulfonyl, 1,1-dimethylbutylsulfonyl, 1,2-dimethylbutylsulfonyl, 1,3-dimethylbutylsulfonyl, 2,2-dimethylbutylsulfonyl, 2,3-dimethylbutylsulfonyl, 3,3-dimethylbutylsulfonyl, 1-ethylbutylsulfonyl, 2-ethylbutylsulfonyl, 1,1,2-trimethylpropylsulfonyl, 1,2,2-trimethylpropylsulfonyl, 1-ethyl-1-methylpropylsulfonyl and 1-ethyl-2-methylpropylsulfonyl; 
     C 1 -C 4 -haloalkylsulfonyl: a C 1 -C 4 -alkylsulfonyl radical as mentioned above which is partially or fully substituted by fluorine, chlorine, bromine and/or iodine, i.e., for example, fluoromethylsulfonyl, difluoromethylsulfonyl, trifluoromethylsulfonyl, chlorodifluoromethylsulfonyl, bromodifluoromethylsulfonyl, 2-fluoroethylsulfonyl, 2-chloroethylsulfonyl, 2-bromoethylsulfonyl, 2-iodoethylsulfonyl, 2,2-difluoroethylsulfonyl, 2,2,2-trifluoroethylsulfonyl, 2-chloro-2-fluoroethylsulfonyl, 2-chloro-2,2-difluoroethylsulfonyl, 2,2-dichloro-2-fluoroethylsulfonyl, 2,2,2-trichloroethylsulfonyl, pentafluoroethylsulfonyl, 2-fluoropropylsulfonyl, 3-fluoropropylsulfonyl, 2-chloropropylsulfonyl, 3-chloropropylsulfonyl, 2-bromopropylsulfonyl, 3-bromopropylsulfonyl, 2,2-difluoropropylsulfonyl, 2,3-difluoropropylsulfonyl, 2,3-dichloropropylsulfonyl, 3,3,3-trifluoropropylsulfonyl, 3,3,3-trichloropropylsulfonyl, 2,2,3,3,3-pentafluoropropylsulfonyl, heptafluoropropylsulfonyl, 1-(fluoromethyl)-2-fluoroethylsulfonyl, 1-(chloromethyl)-2-chloroethylsulfonyl, 1-(bromomethyl)-2-bromoethylsulfonyl, 4-fluorobutylsulfonyl, 4-chlorobutylsulfonyl, 4-bromobutylsulfonyl and nonafluorobutylsulfonyl; 
     C 3 -C 6 -alkenyloxy: for example prop-1-en-1-yloxy, prop-2-en-1-yloxy, 1-methylethenyloxy, buten-1-yloxy, buten-2-yloxy, buten-3-yloxy, 1-methylprop-1-en-1-yloxy, 2-methylprop-1-en-1-yloxy, 1-methylprop-2-en-1-yloxy, 2-methylprop-2-en-1-yloxy, penten-1-yloxy, penten-2-yloxy, penten-3-yloxy, penten-4-yloxy, 1-methylbut-1-en-1-yloxy, 2-methylbut-1-en-1-yloxy, 3-methylbut-1-en-1-yloxy, 1-methylbut-2-en-1-yloxy, 2-methylbut-2-en-1-yloxy, 3-methylbut-2-en-1-yloxy, 1-methylbut-3-en-1-yloxy, 2-methylbut-3-en-1-yloxy, 3-methylbut-3-en-1-yloxy, 1,1-dimethylprop-2-en-1-yloxy, 1,2-dimethylprop-1-en-1-yloxy, 1,2-dimethylprop-2-en-1-yloxy, 1-ethylprop-1-en-2-yloxy, 1-ethylprop-2-en-1-yloxy, hex-1-en-1-yloxy, hex-2-en-1-yloxy, hex-3-en-1-yloxy, hex-4-en-1-yloxy, hex-5-en-1-yloxy, 1-methylpent-1-en-1-yloxy, 2-methylpent-1-en-1-yloxy, 3-methylpent-1-en-1-yloxy, 4-methylpent-1-en-1-yloxy, 1-methylpent-2-en-1-yloxy, 2-methylpent-2-en-1-yloxy, 3-methylpent-2-en-1-yloxy, 4-methylpent-2-en-1-yloxy, 1-methylpent-3-en-1-yloxy, 2-methylpent-3-en-1-yloxy, 3-methylpent-3-en-1-yloxy, 4-methylpent-3-en-1-yloxy, 1-methylpent-4-en-1-yloxy, 2-methylpent-4-en-1-yloxy, 3-methylpent-4-en-1-yloxy, 4-methylpent-4-en-1-yloxy, 1,1-dimethylbut-2-en-1-yloxy, 1,1-dimethylbut-3-en-1-yloxy, 1,2-dimethylbut-1-en-1-yloxy, 1,2-dimethylbut-2-en-1-yloxy, 1,2-dimethylbut-3-en-1-yloxy, 1,3-dimethylbut-1-en-1-yloxy, 1,3-dimethylbut-2-en-1-yloxy, 1,3-dimethylbut-3-en-1-yloxy, 2,2-dimethylbut-3-en-1-yloxy, 2,3-dimethylbut-1-en-1-yloxy, 2,3-dimethylbut-2-en-1-yloxy, 2,3-dimethylbut-3-en-1-yloxy, 3,3-dimethylbut-1-en-1-yloxy, 3,3-dimethylbut-2-en-1-yloxy, 1-ethylbut-1-en-1-yloxy, 1-ethylbut-2-en-1-yloxy, 1-ethylbut-3-en-1-yloxy, 2-ethylbut-1-en-1-yloxy, 2-ethylbut-2-en-1-yloxy, 2-ethylbut-3-en-1-yloxy, 1,1,2-trimethylprop-2-en-1-yloxy; 1-ethyl-1-methylprop-2-en-1-yloxy, 1-ethyl-2-methylprop-1-en-1-yloxy and 1-ethyl-2-methylprop-2-en-1-yloxy; 
     C 3 -C 6 -alkenyl: prop-1-en-1-yl, prop-2-en-1-yl, 1-methylethenyl, buten-1-yl, buten-2-yl, buten-3-yl, 1-methylprop-1-en-1-yl, 2-methylprop-1-en-1-yl, 1-methylprop-2-en-1-yl, 2-methylprop-2-en-1-yl, penten-1-yl, penten-2-yl, penten-3-yl, penten-4-yl, 1-methylbut-1-en-1-yl, 2-methylbut-1-en-1-yl, 3-methylbut-1-en-1-yl, 1-methylbut-2-en-1-yl, 2-methylbut-2-en-1-yl, 3-methylbut-2-en-1-yl, 1-methylbut-3-en-1-yl, 2-methylbut-3-en-1-yl, 3-methylbut-3-en-1-yl, 1,1-dimethylprop-2-en-1-yl, 1,2-dimethylprop-1-en-1-yl, 1,2-dimethylprop-2-en-1-yl, 1-ethylprop-1-en-2-yl, 1-ethylprop-2-en-1-yl, hex-1-en-1-yl, hex-2-en-1-yl, hex-3-en-1-yl, hex-4-en-1-yl, hex-5en-1-yl, 1-methylpent-1-en-1-yl, 2-methylpent-1-en-1-yl, 3-methylpent-1-en-1-yl, 4-methylpent-1-en-1-yl, 1-methylpent-2-en-1-yl, 2-methylpent-2-en-1-yl, 3-methylpent-2-en-1-yl, 4-methylpent-2-en-1-yl, 1-methylpent-3-en-1-yl, 2-methylpent-3-en-1-yl, 3-methylpent-3-en-1-yl, 4-methylpent-3-en-1-yl, 1-methylpent-4-en-1-yl, 2-methylpent-4-en-1-yl, 3-methylpent-4-en-1-yl, 4-methylpent-4-en-1-yl, 1,1-dimethylbut-2-en-1-yl, 1,1-dimethylbut-3-en-1-yl, 1,2-dimethylbut-1-en-1-yl, 1,2-dimethylbut-2-en-1-yl, 1,2-dimethylbut-3-en-1-yl, 1,3-dimethylbut-1-en-1-yl, 1,3-dimethylbut-2-en-1-yl, 1,3-dimethylbut-3-en-1-yl, 2,2-dimethylbut-3-en-1-yl, 2,3-dimethylbut-1-en-1-yl, 2,3-dimethylbut-2-en-1-yl, 2,3-dimethylbut-3-en-1-yl, 3,3-dimethylbut-1-en-1-yl, 3,3-dimethylbut-2-en-1-yl, 1-ethylbut-1-en-1-yl, 1-ethylbut-2-en-1-yl, 1-ethylbut-3-en-1-yl, 2-ethylbut-1-en-1-yl, 2-ethylbut-2-en-1-yl, 2-ethylbut-3-en-1-yl, 1,1,2-trimethylprop-2-en-1-yl, 1-ethyl-1-methylprop-2-en-1-yl, 1-ethyl-2-methylprop-1-en-1-yl and 1-ethyl-2-methylprop-2-en-1-yl. 
     The term “cyclic ring system having 3 to 14 ring atoms” denotes: C 3 -C 8 -cycloalkyl, C 3 -C 8 -cycloalkenyl, a bi- or tricyclic carbocyclic or heterocyclic ring system having up to 14 ring atoms, where the ring system may be saturated or contain one, two or three double bonds and, in the case of the heterocyclic rings, may contain one to three heteroatoms selected from the group consisting of oxygen, nitrogen and sulfur. The “cyclic ring systems having 3 to 14 ring atoms” may be partially or fully halogenated and/or may carry one to three of the following groups: 
     C 1 -C 4 -alkyl, C 1 -C 4 -alkoxy, C 1 -C 4 -haloalkyl or C 1 -C 4 -haloalkoxy. 
     Examples of other meanings are: 
     C 3 -C 6 -cycloalkyl: cyclopropyl, cyclobutyl, cyclopentyl or cyclohexyl; 
     C 3 -C 8 -cycloalkyl: C 3 -C 6 -cycloalkyl as mentioned above, and also cycloheptyl or cyclooctyl; 
     C 5 -C 6 -cycloalkenyl: cyclopentenyl or cyclohexenyl; 
     C 3 -C 6 -cycloalkenyl: C 5 -C 6 -cycloalkenyl as mentioned above, and also cyclopropenyl or cyclobutenyl; 
     C 3 -C 8 -cycloalkenyl: C 3 -C 6 -cycloalkenyl as mentioned above, and also cycloheptenyl or cyclooctenyl; 
     bi- or tricyclic ring system: for example adamantyl, norbornyl, camphyl, camphenyl or norbornenyl. 
     The phenyl rings are preferably unsubstituted or carry one to three halogen atoms and/or one nitro group, one cyano group, one or two methyl, trifluoromethyl, methoxy or trifluoromethoxy groups. 
     Emphasis is given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where the variables both on their own and in combination with one another have the following meanings: 
     X is O, NR 6  or CR 7 R 8 ; 
     Y is O, S, NR 9  or CR 10 R 11 ; 
     R 1  is nitro, halogen, C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy; particularly preferably halogen, such as fluorine, chlorine or bromine, C 1 -C 4 -alkyl, such as methyl or ethyl, or C 1 -C 4 -alkoxy, such as methoxy or ethoxy; with very particular preference chlorine, methyl or methoxy; 
     R 2 ,R 3 ,R 7 ,R 8 ,R 10 ,R 11  are hydrogen, C 1 -C 4 -alkyl or C 1 -C 4 -haloalkyl; particularly preferably hydrogen, methyl, ethyl, propyl, 1-methylethyl, fluoromethyl or chloromethyl; with very particular preference hydrogen, methyl, ethyl or chloromethyl; 
     or 
     R 3  and R 6  or R 3  and R 8  or R 3  and R 9  or R 3  and R 11  together form a bond; 
     R 4  is halogen, nitro, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy, C 1 -C 4 -haloalkoxy, C 1 -C 4 -alkylthio or C 1 -C 4 -alkylsulfonyl; particularly preferably halogen, such as chlorine or bromine, nitro, C 1 -C 2 -haloalkyl, such as difluoromethyl or trifluoromethyl, C 1 -C 2 -alkoxy, such as methoxy or ethoxy, C 1 -C 2 -haloalkoxy, such as difluoromethoxy, chlorodifluoromethoxy or trifluoromethoxy, C 1 -C 3 -alkylthio, such as methylthio, ethylthio or 1-methyl-1-ethylthio, or C 1 -C 3 -alkylsulfonyl, such as methylsulfonyl, ethylsulfonyl, 1-methylethylsulfonyl or propylsulfonyl; 
     R 5  is hydrogen, halogen or methyl or ethyl; particularly preferably hydrogen, chlorine or methyl; with very particular preference hydrogen; 
     R 6 , R 9  are hydrogen or C 1 -C 4 -alkyl; particularly preferably hydrogen, methyl or ethyl; with very particular preference methyl; 
     R 12  is hydroxyl, C 1 -C 6 -alkoxy, C 3 -C 6 -alkenyloxy, C 1 -C 6 -alkylsulfonyloxy, C 1 -C 6 -alkylcarbonyloxy, phenylsulfonyloxy or phenylcarbonyloxy, where the phenyl radical of the two last-mentioned substituents may be partially or fully halogenated and/or may carry one to three of the following groups: nitro, cyano, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy or C 1 -C 4 -haloalkoxy; particularly preferably hydroxyl, C 1 -C 4 -alkoxy, C 3 -C 6 -alkenyloxy, C 1 -C 4 -alkylsulfonyloxy, C 1 -C 4 -alkylcarbonyloxy, phenylsulfonyloxy or phenylcarbonyloxy, where the phenyl radical of the two last-mentioned substituents may be partially or fully halogenated and/or may carry one to three of the following groups: nitro, cyano, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy or C 1 -C 4 -haloalkoxy; 
     R 13  is C 3 -C 8 -cycloalkyl, C 3 -C 8 -cycloalkenyl, a bi- or tricyclic carbocyclic or heterocyclic ring system having up to 14 ring atoms, where the ring system may be saturated or contain one, two or three double bonds and, in the case of the heterocyclic rings, may contain one to three heteroatoms selected from the group consisting of oxygen, nitrogen and sulfur. The “cyclic ring systems having 3 to 14 ring atoms” may be partially or fully halogenated and/or may carry one to three of the following groups: C 1 -C 4 -alkyl, C 1 -C 4 -alkoxy, C 1 -C 4 -haloalkyl or C 1 -C 4 -haloalkoxy; 
     particularly preferably C 3 -C 8 -cycloalkyl, C 3 -C 8 -cycloalkenyl or a bi- or tricyclic carbocyclic ring system which contains up to 14 ring atoms and is saturated or contains one, two or three double bonds, and where the radicals mentioned may be partially or fully halogenated and/or may carry one to three of the following groups: C 1 -C 4 -alkyl, C 1 -C 4 -alkoxy, C 1 -C 4 -haloalkyl or C 1 -C 4 -haloalkoxy; with very particular preference C 3 -C 6 -cycloalkyl, C 5 -C 6 -cycloalkenyl or a bi- or tricyclic carbocyclic ring system selected from the group consisting of: adamantyl, norbornyl, camphyl, camphenyl or norbornenyl; more preferably C 3 -C 6 -cycloalkyl; with most preference cyclopropyl; 
     R 14  is hydrogen or C 1 -C 4 -alkyl; particularly preferably hydrogen or methyl. 
     Preference is given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where: 
     X is O; 
     R 1  is nitro, halogen, C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy; particularly preferably halogen, C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy; with particular preference halogen, such as fluorine, chlorine or bromine, methyl or ethyl or methoxy or ethoxy; with very particular preference chlorine, methyl or methoxy; 
     R 4  is halogen, nitro, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy, C 1 -C 4 -haloalkoxy, C 1 -C 4 -alkylthio or C 1 -C 4 -alkylsulfonyl; particularly preferably halogen, such as chlorine or bromine, nitro, C 1 -C 2 -haloalkyl, such as difluoromethyl or trifluoromethyl, C 1 -C 2 -alkoxy, C 1 -C 2 -haloalkoxy, such as difluoromethoxy, chlorodifluoromethoxy or trifluoromethoxy, C 1 -C 2 -alkylthio, such as methylthio or ethylthio, or C 1 -C 2 -alkylsulfonyl, such as methylsulfonyl or ethylsulfonyl. 
     Particular preference is given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where 
     X is O; 
     Y is CR 10 R 11 ; 
     R 1  is halogen, C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy; particularly preferably halogen, such as fluorine, chlorine or bromine, methyl or ethyl or methoxy or ethoxy; with very particular preference chlorine, methyl or methoxy; 
     R 2 ,R 3 ,R 10 ,R 11  are hydrogen, C 1 -C 4 -alkyl; or R 3  and R 11  together form a bond; particularly preferably hydrogen, methyl or ethyl; or R 3  and R 11  together form a bond; 
     R 4  is nitro, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy or C 1 -C 4 -haloalkoxy; particularly preferably nitro, C 1 -C 2 -haloalkyl, such as difluoromethyl or trifluoromethyl, C 1 -C 2 -alkoxy or C 1 -C 2 -haloalkoxy, such as difluoromethoxy; 
     R 5  is hydrogen; 
     R 12  is hydroxyl, C 1 -C 6 -alkylsulfonyloxy, C 1 -C 6 -alkylcarbonyloxy, phenylsulfonyloxy or phenylcarbonyloxy, where the phenyl radical of the two last-mentioned substituents may be partially or fully halogenated and/or may carry one to three of the following groups: nitro, cyano, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy or C 1 -C 4 -haloalkoxy; particularly preferably hydroxyl; 
     R 13  is C 3 -C 6 -cycloalkyl, C 5 -C 6 -cycloalkenyl or a bi- or tricyclic carbocyclic ring system selected from the group consisting of: adamantyl, norbornyl, camphyl, camphenyl and norbornenyl; particularly preferably C 3 -C 6 -cycloalkyl; with very particular preference cyclopropyl. 
     Most preference is given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where 
     X is O; 
     Y is CR 10 R 11 ; 
     R 2 ,R 3 ,R 10 ,R 11  are hydrogen or methyl or ethyl; preferably hydrogen or methyl. 
     Most preference is also given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where 
     X is O; 
     Y is CR 10 R 11 ; 
     R 2 ,R 10  are hydrogen or methyl or ethyl; preferably hydrogen or methyl; 
     R 3  and R 11  together form a bond. 
     Particular preference is also given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where 
     X is O; 
     Y is CR 10 R 11 ; 
     R 1  is halogen, C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy; particularly preferably halogen, such as fluorine, chlorine or bromine, methyl or ethyl or methoxy or ethoxy; with particular preference chlorine, methyl or methoxy; 
     R 2 ,R 3 ,R 10 ,R 11  are hydrogen or C 1 -C 4 -alkyl; or R 3  and R 11  together form a bond; particularly preferably hydrogen, methyl or ethyl; or R 3  and R 11  together form a bond; 
     R 4  is halogen, C 1 -C 4 -alkylthio or C 1 -C 4 -alkylsulfonyl; particularly preferably chlorine or bromine, methylthio, ethylthio or 1-methyl-1-ethylthio or methylsulfonyl, ethylsulfonyl, 1-methylethylsulfonyl or propylsulfonyl; 
     R 5  is hydrogen; 
     R 12  is hydroxyl, C 1 -C 6 -alkylsulfonyloxy, C 1 -C 6 -alkylcarbonyloxy, phenylsulfonyloxy or phenylcarbonyloxy, where the phenyl radical of the two last-mentioned substituents may be partially or fully halogenated and/or may carry one to three of the following groups: nitro, cyano, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy or C 1 -C 4 -haloalkoxy; particularly preferably hydroxyl; 
     R 13  is C 3 -C 6 -cycloalkyl, C 5 -C 6 -cycloalkenyl or a bi- or tricyclic ring system selected from the group consisting of: adamantyl, norbornyl, camphyl, camphenyl and norbornenyl; particularly preferably C 3 -C 6 -cycloalkyl; with particular preference cyclopropyl. 
     Most preference is given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where 
     X is O; 
     Y is CR 10 R 11 ; 
     R 2 ,R 3 ,R 10 ,R 11  are hydrogen or methyl or ethyl; preferably hydrogen or methyl. 
     Most preference is also given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where 
     X is O; 
     Y is CR 10 R 11 ; 
     R 2 ,R 10  are hydrogen or methyl or ethyl; preferably hydrogen or methyl; 
     R 3  and R 11  together form a bond. 
     Preference is also given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where the variables have the following meanings: 
     X is NR 6 ; 
     R 1  is nitro, halogen, C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy; particularly preferably halogen, C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy; with particular preference halogen, such as fluorine, chlorine or bromine, methyl or ethyl or methoxy or ethoxy; with very particular preference chlorine, methyl or methoxy; 
     R 4  is halogen, nitro, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy, C 1 -C 4 -haloalkoxy, C 1 -C 4 -alkylthio or C 1 -C 4 -alkylsulfonyl; particularly preferably halogen, such as chlorine or bromine, nitro, C 1 -C 2 -haloalkyl, such as difluoromethyl or trifluoromethyl, C 1 -C 2 -alkoxy, such as methoxy or ethoxy, C 1 -C 2 -haloalkoxy, such as difluoromethoxy, chlorodifluoromethoxy or trifluoromethoxy, C 1 -C 2 -alkylthio, such as methylthio or ethylthio, or C 1 -C 2 -alkylsulfonyl, such as methylsulfonyl or ethylsulfonyl. 
     Particular preference is given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where 
     X is N(C 1 -C 6 -alkyl); particularly preferably N-methyl, N-ethyl, N-(1-methyl-1-ethyl) or N-propyl; 
     Y is NR 9  or CR 10 R 11 ; 
     R 1  is halogen, C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy; particularly preferably halogen, such as fluorine, chlorine or bromine, methyl or ethyl or methoxy or ethoxy; with particular preference chlorine, methyl or methoxy; 
     R 2 ,R 3 ,R 10 ,R 11  are hydrogen or C 1 -C 4 -alkyl; or R 3  and R 9  or R 3  and R 11  together form a bond; particularly preferably hydrogen, methyl or ethyl; or R 3  and R 9  or R 3  and R 11  together form a bond; 
     R 4  is nitro, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy or C 1 -C 4 -haloalkoxy; particularly preferably nitro, C 1 -C 2 -haloalkyl, such as difluoromethyl or trifluoromethyl, C 1 -C 2 -alkoxy or C 1 -C 2 -haloalkoxy, such as difluoromethoxy; 
     R 5  is hydrogen; 
     R 9  is hydrogen or C 1 -C 4 -alkyl; particularly preferably C 1 -C 4 -alkyl; with particular preference methyl or ethyl; 
     R 12  is hydroxyl, C 1 -C 6 -alkylsulfonyloxy, C 1 -C 6 -alkylcarbonyloxy, phenylsulfonyloxy or phenylcarbonyloxy, where the phenyl radical of the two last-mentioned substituents may be partially or fully halogenated and/or may carry one to three of the following groups: nitro, cyano, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy or C 1 -C 4 -haloalkoxy; particularly preferably hydroxyl; 
     R 13  is C 3 -C 6 -cycloalkyl, C 5 -C 6 -cycloalkenyl or a bi- or tricyclic carbocyclic ring system selected from the group consisting of: adamantyl, norbornyl, camphyl, camphenyl and norbornenyl; particularly preferably C 3 -C 6 -cycloalkyl; with particular preference cyclopropyl. 
     Most preference is given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where 
     X is N-(C 1 -C 6 -alkyl); particularly preferably N-methyl, N-ethyl, N-(1-methyl-1-ethyl) or N-propyl; 
     Y is CR 10 R 11 ; 
     R 2 ,R 3 ,R 10 ,R 11  are hydrogen or C 1 -C 4 -alkyl; preferably hydrogen, methyl or ethyl; particularly preferably hydrogen or methyl. 
     Most preference is also given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where 
     X is N-(C 1 -C 6 -alkyl); particularly preferably N-methyl, N-ethyl, N-(1-methyl-1-ethyl) or N-propyl; 
     Y is NR 9  or CR 10 R 11 ; 
     R 2 ,R 10  are hydrogen or C 1 -C 4 -alkyl; preferably hydrogen, methyl or ethyl; with particular preference hydrogen or methyl; 
     R 3  and R 9  or R 3  and R 11  together form a bond. 
     Particular preference is also given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where 
     X is N-(C 1 -C 6 -alkyl); particularly preferably N-methyl, N-ethyl, N-(1-methyl-1-ethyl) or N-propyl; 
     Y is NR 9  or CR 10 R 11 ; 
     R 1  is halogen, C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy; particularly preferably halogen, such as fluorine, chlorine or bromine, methyl or ethyl or methoxy or ethoxy; with particular preference chlorine, methyl or methoxy; 
     R 2 ,R 3 ,R 10 ,R 11  are hydrogen or C 1 -C 4 -alkyl; or R 3  and R 9  or R 3  and R 11  together form a bond; particularly preferably hydrogen, methyl or ethyl; or R 3  and R 9  or R 3  and R 11  together form a bond; 
     R 4  is halogen, C 1 -C 4 -alkylthio or C 1 -C 4 -alkylsulfonyl; particularly preferably chlorine or bromine, methylthio, ethylthio or 1-methyl-1-ethylthio or methylsulfonyl, ethylsulfonyl, 1-methylethylsulfonyl or propylsulfonyl; 
     R 5  is hydrogen; 
     R 9  is hydrogen or C 1 -C 4 -alkyl; particularly preferably C 1 -C 4 -alkyl; with particular preference methyl or ethyl; 
     R 12  is hydroxyl, C 1 -C 6 -alkylsulfonyloxy, C 1 -C 6 -alkylcarbonyloxy, phenylsulfonyloxy or phenylcarbonyloxy, where the phenyl radical of the two last-mentioned substituents may be partially or fully halogenated and/or may carry one to three of the following groups: nitro, cyano, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy or C 1 -C 4 -haloalkoxy; particularly preferably hydroxyl; 
     R 13  is C 3 -C 6 -cycloalkyl, C 5 -C 6 -cycloalkenyl or a bi- or tricyclic carbocyclic ring system, selected from the group consisting of: adamantyl, norbornyl, camphyl, camphenyl and norbornenyl; particularly preferably C 1 -C 6 -cycloalkyl; with particular preference cyclopropyl. 
     Most preference is given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where 
     X is N-(C 1 -C 6 -alkyl); particularly preferably N-methyl, N-ethyl, N-(1-methyl-1-ethyl) or N-propyl; 
     Y is CR 10 R 11 ; 
     R 2 ,R 3 ,R 10 ,R 11  are hydrogen or C 1 -C 4 -alkyl; preferably hydrogen, methyl or ethyl; with particular preference hydrogen or methyl. 
     Most preference is also given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where 
     X is N-(C 1 -C 6 -alkyl); particularly preferably N-methyl, N-ethyl, N-(1-methyl-1-ethyl) or N-propyl; 
     Y is NR 9  or CR 10 R 11 ; 
     R 2 ,R 10  are hydrogen or C 1 -C 4 -alkyl; preferably hydrogen, methyl or ethyl; with particular preference hydrogen or methyl; 
     R 3  and R 9  or R 3  and R 11  together form a bond. 
     Particular preference is also given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where 
     X is NR 6 ; 
     Y is O, S or N-(C 1 -C 6 -alkyl); particularly preferably O, S or N-methyl, N-ethyl, N-(1-methyl-1-ethyl) or N-propyl; 
     R 1  is halogen, C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy; particularly preferably halogen, such as fluorine, chlorine or bromine, methyl or ethyl or methoxy or ethoxy; with particular preference chlorine, methyl or methoxy; 
     R 2  is hydrogen or C 1 -C 4 -alkyl; particularly preferably hydrogen, methyl or ethyl; 
     R 3  and R 6  together form a bond; 
     R 5  is hydrogen; 
     R 12  is hydroxyl, C 1 -C 6 -alkylsulfonyloxy, C 1 -C 6 -alkylcarbonyloxy, phenylsulfonyloxy or phenylcarbonyloxy, where the phenyl radical of the two last-mentioned substituents may be partially or fully halogenated and/or may carry one to three of the following groups: nitro, cyano, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy or C 1 -C 4 -haloalkoxy; particularly preferably hydroxyl; 
     R 13  is C 3 -C 6 -cycloalkyl, C 5 -C 6 -cycloalkenyl or a bi- or tricyclic carbocyclic ring system selected from the group consisting of: adamantyl, norbornyl, camphyl, camphenyl and norbornenyl; particularly preferably C 3 -C 6 -cycloalkyl; with particular preference cyclopropyl. 
     Most preference is given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where 
     R 4  is nitro, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy or C 1 -C 4 -haloalkoxy; particularly preferably nitro, C 1 -C 2 -haloalkyl, such as difluoromethyl or trifluoromethyl, C 1 -C 2 -alkoxy or C 1 -C 2 -haloalkoxy, such as difluoromethoxy. 
     Most preference is also given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where 
     R 4  is halogen, C 1 -C 4 -alkylthio or C 1 -C 4 -alkylsulfonyl; particularly preferably chlorine or bromine, methylthio, ethylthio or 1-methyl-1-ethylthio or methylsulfonyl, ethylsulfonyl, 1-methylethylsulfonyl or propylsulfonyl. 
     Preference is also given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where: 
     X is CR 7 R 8 ; 
     R 1  is nitro, halogen, C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy; particularly preferably halogen, C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy; with particular preference halogen, such as fluorine, chlorine or bromine, methyl or ethyl or methoxy or ethoxy; with very particular preference chlorine, methyl or methoxy; 
     R 4  is halogen, nitro, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy, C 1 -C 4 -haloalkoxy, C 1 -C 4 -alkylthio or C 1 -C 4 -alkylsulfonyl; particularly preferably halogen, such as chlorine or bromine, nitro, C 1 -C 2 -haloalkyl, such as difluoromethyl or trifluoromethyl, C 1 -C 2 -alkoxy, such as methoxy or ethoxy, C 1 -C 2 -haloalkoxy, such as difluoromethoxy, chlorodifluoromethoxy or trifluoromethoxy, C 1 -C 2 -alkylthio, such as methylthio or ethylthio, or C 1 -C 2 -alkylsulfonyl, such as methylsulfonyl or ethylsulfonyl. 
     Particular preference is given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where 
     X is CR 7 R 8 ; 
     Y is O, S or NR 9 ; 
     R 1  is halogen, C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy; particularly preferably halogen, such as fluorine, chlorine or bromine, methyl or ethyl, methoxy or ethoxy; with particular preference chlorine, methyl or methoxy; 
     R 2 ,R 3 ,R 7 ,R 8  are hydrogen or C 1 -C 4 -alkyl; or R 3  and R 8  together form a bond; particularly preferably hydrogen, methyl or ethyl; or R 3  and R 8  together form a bond; 
     R 4  is nitro, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy or C 1 -C 4 -haloalkoxy; particularly preferably nitro, C 1 -C 2 -haloalkyl, such as difluoromethyl or trifluoromethyl, C 1 -C 2 -alkoxy or C 1 -C 2 -haloalkoxy, such as difluoromethyloxy; 
     R 5  is hydrogen; 
     R 9  is hydrogen or C 1 -C 4 -alkyl; particularly preferably C 1 -C 4 -alkyl; 
     R 12  is hydroxyl, C 1 -C 6 -alkylsulfonyloxy, C 1 -C 6 -alkylcarbonyloxy, phenylsulfonyloxy or phenylcarbonyloxy, where the phenyl radical of the two last-mentioned substituents may be partially or fully halogenated and/or may carry one to three of the following groups: nitro, cyano, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy or C 1 -C 4 -haloalkoxy; particularly preferably hydroxyl; 
     R 13  is C 3 -C 6 -cycloalkyl, C 5 -C 6 -cycloalkenyl or a bi or tricyclic carbocyclic ring system selected from the group consisting of: adamantyl, norbornyl, camphyl, camphenyl and norbornenyl; particularly preferably C 3 -C 6 -cycloalkyl; with particular preference cyclopropyl. 
     Most preference is given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where 
     X is CR 7 R 8 ; 
     Y is O, S or NR 9 ; 
     R 2 ,R 3 ,R 7 ,R 8  are hydrogen or C 1 -C 4 -alkyl; preferably hydrogen, methyl or ethyl; particularly preferably hydrogen or methyl; 
     R 9  is hydrogen or C 1 -C 4 -alkyl; preferably C 1 -C 4 -alkyl. 
     Most preference is also given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where 
     X is CR 7 R 8 ; 
     Y is O, S or NR 9 ; 
     R 2 ,R 7  are hydrogen or C 1 -C 4 -alkyl; preferably hydrogen, methyl or ethyl; particularly preferably hydrogen or methyl; 
     R 3  and R 8  together form a bond; 
     R 9  is hydrogen or C 1 -C 4 -alkyl; preferably C 1 -C 4 -alkyl. 
     Especially preferred in this case are the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where Y is S. 
     Particular preference is also given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where 
     X is CR 7 R 8 ; 
     Y is O, S or NR 9 ; 
     R 1  is halogen, C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy; particularly preferably halogen, such as fluorine, chlorine or bromine, methyl or ethyl or methoxy or ethoxy; with particular preference chlorine, methyl or methoxy; 
     R 2 ,R 3 ,R 7 ,R 8  are hydrogen or C 1 -C 4 -alkyl; or R 3  and R 8  together form a bond; particularly preferably hydrogen, methyl or ethyl; or R 3  and R 8  together form a bond; 
     R 4  is halogen, C 1 -C 4 -alkylthio or C 1 -C 4 -alkylsulfonyl; particularly preferably chlorine or bromine, methylthio, ethylthio or 1-methyl-1-ethylthio or methylsulfonyl, ethylsulfonyl, 1-methylethylsulfonyl or propylsulfonyl; 
     R 5  is hydrogen; 
     R 9  is hydrogen or C 1 -C 4 -alkyl; particularly preferably C 1 -C 4 -alkyl; with particular preference methyl or ethyl; 
     R 12  is hydroxyl, C 1 -C 6 -alkylsulfonyloxy, C 1 -C 6 -alkylcarbonyloxy, phenylsulfonyloxy or phenylcarbonyloxy, where the phenyl radical of the two last-mentioned substituents may be partially or fully halogenated and/or may carry one to three of the following groups: nitro, cyano, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy or C 1 -C 4 -haloalkoxy; particularly preferably hydroxyl; 
     R 13  is C 3 -C 6 -cycloalkyl, C 5 -C 6 -cycloalkenyl or a bi- or tricyclic carbocyclic ring system selected from the group consisting of: adamantyl, norbornyl, camphyl, camphenyl and norbornenyl; particularly preferably C 3 -C 6 -cycloalkyl; with particular preference cyclopropyl. 
     Preference is furthermore given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where 
     X is CR 7 R 8 ; 
     Y is O, S or NR 9 ; 
     R 2 ,R 3 ,R 7 ,R 8  are hydrogen or C 1 -C 4 -alkyl; preferably hydrogen, methyl or ethyl; particularly preferably hydrogen or methyl; 
     R 9  is hydrogen or C 1 -C 4 -alkyl; preferably C 1 -C 4 -alkyl. 
     Most preference is also given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where 
     X is CR 7 R 8 ; 
     Y is O, S or NR 9 ; 
     R 2 ,R 7  are hydrogen or C 1 -C 4 -alkyl; preferably hydrogen, methyl or ethyl; with particular preference hydrogen or methyl; 
     R 3  and R 8  together form a bond; 
     R 9  is hydrogen or C 1 -C 4 -alkyl; preferably C 1 -C 4 -alkyl. 
     Especially preferred in this case are the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where Y is S. 
     Preference is also given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where the variables have the following meanings: 
     X is O; 
     Y is CR 10 R 11 ; 
     R 1  is halogen, C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy; particularly preferably chlorine, methyl or methoxy; also particularly preferably halogen or C 1 -C 4 -alkyl; with particular preference chlorine or methyl; 
     R 1 ,R 3 ,R 10 ,R 11  are hydrogen; 
     R 4  is C 1 -C 4 -alkylsulfonyl; particularly preferably methylsulfonyl; 
     R 5  is hydrogen; 
     R 12  is hydroxyl, C 1 -C 6 -alkoxy, phenylsulfonyloxy or phenylcarbonyloxy, where the phenyl radical of the two last-mentioned substituents may be partially or fully halogenated and/or may carry one to three of the following groups: nitro, cyano, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy or C 1 -C 4 -haloalkoxy; particularly preferably hydroxyl, C 1 -C 6 -alkoxy or phenylcarbonyloxy, where the phenyl radical may be partially or fully halogenated and/or may carry one to three of the following groups; nitro, cyano, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy or C 1 -C 4 -haloalkoxy; 
     R 13  is C 3 -C 6 -cycloalkyl or a bi- or tricyclic ring system selected from the group consisting of: adamantyl, norbornyl, camphyl, camphenyl or norbornenyl; particularly preferably cyclopropyl, cyclopentyl, 2-norbornyl or 2-adamantyl; with particular preference cyclopentyl or 2-norbornyl; also with particular preference cyclopropyl; 
     R 14  is hydrogen; 
     Preference is also given to the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I where the variables have the following meanings: 
     X is O; 
     Y is CR 10 R 11 ; 
     R 1  is halogen, C 1 -C 4 -alkyl or C 1 -C 4 -alkoxy; 
     R 4  is C 1 -C 4 -alkylsulfonyl; 
     R 13  is C 3 -C 6 -cycloalkyl. 
     Most particularly preferred are the compounds of the formula Ia1 (=I where R 1 =Cl; R 13 =cyclo-C 3 H 5  and R 5  and R 14 =H), in particular the compounds Ia1.1 to Ta1.765 of Table 1, where the radical definitions X, Y and R 1  to R 14  are of particular importance for the compounds according to the invention not only in combination with one another but also in each case on their own.                    
     
       
         
           
               
               
               
               
               
               
               
             
               
                 TABLE 1 
               
               
                   
               
               
                 No. 
                 X 
                 R 2   
                 R 3   
                 Y 
                 R 4   
                 R 12   
               
               
                   
               
             
            
               
                 Ia1.1 
                 O 
                 H 
                 H 
                 CH 2   
                 SCH 3   
                 OH 
               
               
                 Ia1.2 
                 O 
                 H 
                 H 
                 CH 2   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.3 
                 O 
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.4 
                 O 
                 H 
                 H 
                 CH 2   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.5 
                 O 
                 H 
                 H 
                 CH 2   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.6 
                 O 
                 H 
                 H 
                 CH 2   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.7 
                 O 
                 H 
                 H 
                 CH 3   
                 Cl 
                 OH 
               
               
                 Ia1.8 
                 O 
                 H 
                 H 
                 CH 2   
                 Br 
                 OH 
               
               
                 Ia1.9 
                 O 
                 H 
                 H 
                 CH 2   
                 NO 2   
                 OH 
               
               
                 Ia1.10 
                 O 
                 H 
                 H 
                 CH 2   
                 CHF 2   
                 OH 
               
               
                 Ia1.11 
                 O 
                 H 
                 H 
                 CH 2   
                 CF 3   
                 OH 
               
               
                 Ia1.12 
                 O 
                 H 
                 H 
                 CH 2   
                 OCH 3   
                 OH 
               
               
                 Ia1.13 
                 O 
                 H 
                 H 
                 CH 2   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.14 
                 O 
                 H 
                 H 
                 CH 2   
                 OCHF 2   
                 OH 
               
               
                 Ia1.15 
                 O 
                 H 
                 H 
                 CH 2   
                 OCF 3   
                 OH 
               
               
                 Ia1.16 
                 O 
                 CH 3   
                 H 
                 CH 2   
                 SCH 3   
                 OH 
               
               
                 Ia1.17 
                 O 
                 CH 3   
                 H 
                 CH 2   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.18 
                 O 
                 CH 3   
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.19 
                 O 
                 CH 3   
                 H 
                 CH 2   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.20 
                 O 
                 CH 3   
                 H 
                 CH 2   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.21 
                 O 
                 CH 3   
                 H 
                 CH 2   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.22 
                 O 
                 CH 3   
                 H 
                 CH 2   
                 Cl 
                 OH 
               
               
                 Ia1.23 
                 O 
                 CH 3   
                 H 
                 CH 2   
                 Br 
                 OH 
               
               
                 Ia1.24 
                 O 
                 CH 3   
                 H 
                 CH 2   
                 NO 2   
                 OH 
               
               
                 Ia1,25 
                 O 
                 CH 3   
                 H 
                 CH 2   
                 CHF 2   
                 OH 
               
               
                 Ia1.26 
                 O 
                 CH 3   
                 H 
                 CH 2   
                 CF 3   
                 OH 
               
               
                 Ia1.27 
                 O 
                 CH 3   
                 H 
                 CH 2   
                 OCH 3   
                 OH 
               
               
                 Ia1.28 
                 O 
                 CH 3   
                 H 
                 CH 2   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.29 
                 O 
                 CH 3   
                 H 
                 CH 2   
                 OCHF 2   
                 OH 
               
               
                 Ia1.30 
                 O 
                 CH 3   
                 H 
                 CH 2   
                 OCF 3   
                 OH 
               
               
                 Ia1.31 
                 O 
                 CH 3   
                 CH 3   
                 CH 2   
                 SCH 3   
                 OH 
               
               
                 Ia1.32 
                 O 
                 CH 3   
                 CH 3   
                 CH 2   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.33 
                 O 
                 CH 3   
                 CH 3   
                 CH 2   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.34 
                 O 
                 CH 3   
                 CH 3   
                 CH 2   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.35 
                 O 
                 CH 3   
                 CH 3   
                 CH 2   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.36 
                 O 
                 CH 3   
                 CH 3   
                 CH 2   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.37 
                 O 
                 CH 3   
                 CH 3   
                 CH 2   
                 Cl 
                 OH 
               
               
                 Ia1.38 
                 O 
                 CH 3   
                 CH 3   
                 CH 2   
                 Br 
                 OH 
               
               
                 Ia1.39 
                 O 
                 CH 3   
                 CH 3   
                 CH 2   
                 NO 2   
                 OH 
               
               
                 Ia1.40 
                 O 
                 CH 3   
                 CH 3   
                 CH 2   
                 CHF 2   
                 OH 
               
               
                 Ia1.41 
                 O 
                 CH 3   
                 CH 3   
                 CH 2   
                 CF 3   
                 OH 
               
               
                 Ia1.42 
                 O 
                 CH 3   
                 CH 3   
                 CH 2   
                 OCH 3   
                 OH 
               
               
                 Ia1.43 
                 O 
                 CH 3   
                 CH 3   
                 CH 2   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.44 
                 O 
                 CH 3   
                 CH 3   
                 CH 2   
                 OCHF 2   
                 OH 
               
               
                 Ia1.45 
                 O 
                 CH 3   
                 CH 3   
                 CH 2   
                 OCF 3   
                 OH 
               
               
                 Ia1.46 
                 O 
                 CH 2 Cl 
                 H 
                 CH 2   
                 SCH 3   
                 OH 
               
               
                 Ia1.47 
                 O 
                 CH 2 Cl 
                 H 
                 CH 2   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.48 
                 O 
                 CH 2 Cl 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.49 
                 O 
                 CH 2 Cl 
                 H 
                 CH 2   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.50 
                 O 
                 CH 2 Cl 
                 H 
                 CH 2   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.51 
                 O 
                 CH 2 Cl 
                 H 
                 CH 2   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.52 
                 O 
                 CH 2 Cl 
                 H 
                 CH 2   
                 Cl 
                 OH 
               
               
                 Ia1.53 
                 O 
                 CH 2 Cl 
                 H 
                 CH 2   
                 Br 
                 OH 
               
               
                 Ia1.54 
                 O 
                 CH 2 Cl 
                 H 
                 CH 2   
                 NO 2   
                 OH 
               
               
                 Ia1.55 
                 O 
                 CH 2 Cl 
                 H 
                 CH 2   
                 CHF 2   
                 OH 
               
               
                 Ia1.56 
                 O 
                 CH 2 Cl 
                 H 
                 CH 2   
                 CF 3   
                 OH 
               
               
                 Ia1.57 
                 O 
                 CH 2 Cl 
                 H 
                 CH 2   
                 OCH 3   
                 OH 
               
               
                 Ia1.58 
                 O 
                 CH 2 Cl 
                 H 
                 CH 2   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.59 
                 O 
                 CH 2 Cl 
                 H 
                 CH 2   
                 OCHF 2   
                 OH 
               
               
                 Ia1.60 
                 O 
                 CH 2 Cl 
                 H 
                 CH 2   
                 OCF 3   
                 OH 
               
               
                 Ia1.61 
                 O 
                 CH 2 CH 3   
                 H 
                 CH 2   
                 SCH 3   
                 OH 
               
               
                 Ia1.62 
                 O 
                 CH 2 CH 3   
                 H 
                 CH 2   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.63 
                 O 
                 CH 2 CH 3   
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.64 
                 O 
                 CH 2 CH 3   
                 H 
                 CH 2   
                 SO 3 CH 2 CH 3   
                 OH 
               
               
                 Ia1.65 
                 O 
                 CH 2 CH 3   
                 H 
                 CH 2   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.66 
                 O 
                 CH 2 CH 3   
                 H 
                 CH 2   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.67 
                 O 
                 CH 2 CH 3   
                 H 
                 CH 2   
                 Cl 
                 OH 
               
               
                 Ia1.68 
                 O 
                 CH 2 CH 3   
                 H 
                 CH 2   
                 Br 
                 OH 
               
               
                 Ia1.69 
                 O 
                 CH 2 CH 3   
                 H 
                 CH 2   
                 NO 2   
                 OH 
               
               
                 Ia1.70 
                 O 
                 CH 2 CH 3   
                 H 
                 CH 2   
                 CHF 2   
                 OH 
               
               
                 Ia1.71 
                 O 
                 CH 2 CH 3   
                 R 
                 CH 2   
                 CF 3   
                 OH 
               
               
                 Ia1.72 
                 O 
                 CH 2 CH 3   
                 H 
                 CH 2   
                 OCH 3   
                 OH 
               
               
                 Ia1.73 
                 O 
                 CH 2 CH 3   
                 H 
                 CH 2   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.74 
                 O 
                 CH 2 CH 3   
                 H 
                 CH 2   
                 OCHF 2   
                 OH 
               
               
                 Ia1.75 
                 O 
                 CH 2 CH 3   
                 H 
                 CH 2   
                 OCF 3   
                 OH 
               
               
                 Ia1.76 
                 O 
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 SCH 3   
                 OH 
               
               
                 Ia1.77 
                 O 
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.78 
                 O 
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.79 
                 O 
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.80 
                 O 
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.81 
                 O 
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.82 
                 O 
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 Cl 
                 OH 
               
               
                 Ia1.83 
                 O 
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 Br 
                 OH 
               
               
                 Ia1.84 
                 O 
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 NO 2   
                 OH 
               
               
                 Ia1.85 
                 O 
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 CHF 2   
                 OH 
               
               
                 Ia1.86 
                 O 
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 CF 3   
                 OH 
               
               
                 Ia1.87 
                 O 
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 OCH 3   
                 OH 
               
               
                 Ia1.88 
                 O 
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.89 
                 O 
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 OCHF 2   
                 OH 
               
               
                 Ia1.90 
                 O 
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 OCF 3   
                 OH 
               
               
                 Ia1.91 
                 O 
                 H 
                 H 
                 CH(CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ia1.92 
                 O 
                 H 
                 H 
                 CH(CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.93 
                 O 
                 H 
                 H 
                 CH(CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.94 
                 O 
                 H 
                 H 
                 CH(CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.95 
                 O 
                 H 
                 H 
                 CH(CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.96 
                 O 
                 H 
                 H 
                 CH(CH 3 ) 
                 SO 2 (CH 2 ) 2 CH 3   
                 CH 
               
               
                 Ia1.97 
                 O 
                 H 
                 H 
                 CH(CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ia1.98 
                 O 
                 H 
                 H 
                 CH(CH 3 ) 
                 Br 
                 OH 
               
               
                 Ia1.99 
                 O 
                 H 
                 H 
                 CH(CH 3 ) 
                 NO 2   
                 OH 
               
               
                 Ia1.100 
                 O 
                 H 
                 H 
                 CH(CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ia1.101 
                 O 
                 H 
                 H 
                 CH(CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ia1.102 
                 O 
                 H 
                 H 
                 CH(CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ia1.103 
                 O 
                 H 
                 H 
                 CH(CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.104 
                 O 
                 H 
                 H 
                 CH(CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ia1.105 
                 O 
                 H 
                 H 
                 CH(CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ia1.106 
                 O 
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ia1.107 
                 O 
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.108 
                 O 
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.109 
                 O 
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.110 
                 O 
                 CH 2   
                 H 
                 CH(CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.111 
                 O 
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.112 
                 O 
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ia1.113 
                 O 
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 Br 
                 OH 
               
               
                 Ia1.114 
                 O 
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 NO 2   
                 OH 
               
               
                 Ia1.115 
                 O 
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ia1.116 
                 O 
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ia1.117 
                 O 
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ia1.118 
                 O 
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.119 
                 O 
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ia1.120 
                 O 
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ia1.121 
                 O 
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ia1.122 
                 O 
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.123 
                 O 
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.124 
                 O 
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.125 
                 O 
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.126 
                 O 
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.127 
                 O 
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ia1.128 
                 O 
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 Br 
                 OH 
               
               
                 Ia1.129 
                 O 
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 NO 2   
                 OH 
               
               
                 Ia1.130 
                 O 
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ia1.131 
                 O 
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ia1.132 
                 O 
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ia1.133 
                 O 
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.134 
                 O 
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ia1.135 
                 O 
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ia1.136 
                 O 
                 H 
                 H 
                 C(CH 3 ) 2   
                 SCH 3   
                 OH 
               
               
                 Ia1.137 
                 O 
                 H 
                 H 
                 C(CH 3 ) 2   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.138 
                 O 
                 H 
                 H 
                 C(CH 3 ) 2   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.139 
                 O 
                 H 
                 H 
                 C(CH 3 ) 2   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.140 
                 O 
                 H 
                 H 
                 C(CH 3 ) 2   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.141 
                 O 
                 H 
                 H 
                 C(CH 3 ) 2   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.142 
                 O 
                 H 
                 H 
                 C(CH 3 ) 2   
                 Cl 
                 OH 
               
               
                 Ia1.143 
                 O 
                 H 
                 H 
                 C(CH 3 ) 2   
                 Br 
                 OH 
               
               
                 Ia1.144 
                 O 
                 H 
                 H 
                 C(CH 3 ) 2   
                 NO 2   
                 OH 
               
               
                 Ia1.145 
                 O 
                 H 
                 H 
                 C(CH 3 ) 2   
                 CHF 2   
                 OH 
               
               
                 Ia1.146 
                 O 
                 H 
                 H 
                 C(CH 3 ) 2   
                 CF 3   
                 OH 
               
               
                 Ia1.147 
                 O 
                 H 
                 H 
                 C(CH 3 ) 2   
                 OCH 3   
                 OH 
               
               
                 Ia1.148 
                 O 
                 H 
                 H 
                 C(CH 3 ) 2   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.149 
                 O 
                 H 
                 H 
                 C(CH 3 ) 2   
                 OCHF 2   
                 OH 
               
               
                 Ia1.150 
                 O 
                 H 
                 H 
                 C(CH 3 ) 2   
                 OCF 3   
                 OH 
               
               
                 Ia1.151 
                 O 
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 SCH 3   
                 OH 
               
               
                 Ia1.152 
                 O 
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.153 
                 O 
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.154 
                 O 
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.155 
                 O 
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.156 
                 O 
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.157 
                 O 
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 Cl 
                 OH 
               
               
                 Ia1.158 
                 O 
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 Br 
                 OH 
               
               
                 Ia1.159 
                 O 
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 NO 2   
                 OH 
               
               
                 Ia1.160 
                 O 
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 CHF 2   
                 OH 
               
               
                 Ia1.161 
                 O 
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 CF 3   
                 OH 
               
               
                 Ia1.162 
                 O 
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 OCH 3   
                 OH 
               
               
                 Ia1.163 
                 O 
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.164 
                 O 
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 OCHF 2   
                 OH 
               
               
                 Ia1.165 
                 O 
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 OCF 3   
                 OH 
               
               
                 Ia1.166 
                 O 
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 SCH 3   
                 OH 
               
               
                 Ia1.167 
                 O 
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.168 
                 O 
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.169 
                 O 
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.170 
                 O 
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.171 
                 O 
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.172 
                 O 
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 Cl 
                 OH 
               
               
                 Ia1.173 
                 O 
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 Br 
                 OH 
               
               
                 Ia1.174 
                 O 
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 NO 2   
                 OH 
               
               
                 Ia1.175 
                 O 
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 CHF 2   
                 OH 
               
               
                 Ia1.176 
                 O 
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 CF 3   
                 OH 
               
               
                 Ia1.177 
                 O 
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 OCH 3   
                 OH 
               
               
                 Ia1.178 
                 O 
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.179 
                 O 
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 OCHF 2   
                 OH 
               
               
                 Ia1.180 
                 O 
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 OCF 3   
                 OH 
               
               
                 Ia1.181 
                 NCH 3   
                 H 
                 H 
                 CH 2   
                 SCH 3   
                 OH 
               
               
                 Ia1.182 
                 NCH 3   
                 H 
                 H 
                 CH 2   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.183 
                 NCH 3   
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.184 
                 NCH 3   
                 H 
                 H 
                 CH 2   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.185 
                 NCH 3   
                 H 
                 H 
                 CH 2   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.186 
                 NCH 3   
                 H 
                 H 
                 CH 2   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.187 
                 NCH 3   
                 H 
                 H 
                 CH 2   
                 Cl 
                 OH 
               
               
                 Ia1.188 
                 NCH 3   
                 H 
                 H 
                 CH 2   
                 Br 
                 OH 
               
               
                 Ia1.189 
                 NCH 3   
                 H 
                 H 
                 CH 2   
                 NO 2   
                 OH 
               
               
                 Ia1.190 
                 NCH 3   
                 H 
                 H 
                 CH 2   
                 CHF 2   
                 OH 
               
               
                 Ia1.191 
                 NCH 3   
                 H 
                 H 
                 CH 2   
                 CF 3   
                 OH 
               
               
                 Ia1.192 
                 NCH 3   
                 H 
                 H 
                 CH 2   
                 OCH 3   
                 OH 
               
               
                 Ia1.193 
                 NCH 3   
                 H 
                 H 
                 CH 2   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.194 
                 NCH 3   
                 H 
                 H 
                 CH 2   
                 OCHF 2   
                 OH 
               
               
                 Ia1.195 
                 NCH 3   
                 H 
                 H 
                 CH 2   
                 OCF 3   
                 OH 
               
               
                 Ia1.196 
                 NCH 3   
                 CH 3   
                 H 
                 CH 2   
                 SCH 3   
                 OH 
               
               
                 Ia1.197 
                 NCH 3   
                 CH 3   
                 H 
                 CH 2   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.198 
                 NCH 3   
                 CH 3   
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.199 
                 NCH 3   
                 CH 3   
                 H 
                 CH 2   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.200 
                 NCH 3   
                 CH 3   
                 H 
                 CH 2   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.201 
                 NCH 3   
                 CH 3   
                 H 
                 CH 2   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.202 
                 NCH 3   
                 CH 3   
                 H 
                 CH 2   
                 Cl 
                 OH 
               
               
                 Ia1.203 
                 NCH 3   
                 CH 3   
                 H 
                 CH 2   
                 Br 
                 OH 
               
               
                 Ia1.204 
                 NCH 3   
                 CH 3   
                 H 
                 CH 2   
                 NO 2   
                 OH 
               
               
                 Ia1.205 
                 NCH 3   
                 CH 3   
                 H 
                 CH 2   
                 CHF 2   
                 OH 
               
               
                 Ia1.206 
                 NCH 3   
                 CH 3   
                 H 
                 CH 2   
                 CF 3   
                 OH 
               
               
                 Ia1.207 
                 NCH 3   
                 CH 3   
                 H 
                 CH 2   
                 OCH 3   
                 OH 
               
               
                 Ia1.208 
                 NCH 3   
                 CH 3   
                 H 
                 CH 2   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.209 
                 NCH 3   
                 CH 3   
                 H 
                 CH 2   
                 OCHF 2   
                 OH 
               
               
                 Ia1.210 
                 NCH 3   
                 CH 3   
                 H 
                 CH 2   
                 OCF 3   
                 OH 
               
               
                 Ia1.211 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH 2   
                 SCH 3   
                 OH 
               
               
                 Ia1.212 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH 2   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.213 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH 2   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.214 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH 2   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.215 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH 2   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.216 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH 2   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.217 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH 2   
                 Cl 
                 OH 
               
               
                 Ia1.218 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH 2   
                 Br 
                 OH 
               
               
                 Ia1.219 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH 2   
                 NO 2   
                 OH 
               
               
                 Ia1.220 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH 2   
                 CHF 2   
                 OH 
               
               
                 Ia1.221 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH 2   
                 CF 3   
                 OH 
               
               
                 Ia1.222 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH 2   
                 OCH 3   
                 OH 
               
               
                 Ia1.223 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH 2   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.224 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH 2   
                 OCHF 2   
                 OH 
               
               
                 Ia1.225 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH 2   
                 OCF 3   
                 OH 
               
               
                 Ia1.226 
                 NCH 3   
                 CH 2 Cl 
                 H 
                 CH 2   
                 SCH 3   
                 OH 
               
               
                 Ia1.227 
                 NCH 3   
                 CH 2 Cl 
                 H 
                 CH 2   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.228 
                 NCH 3   
                 CH 2 Cl 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.229 
                 NCH 3   
                 CH 2 Cl 
                 H 
                 CH 2   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.230 
                 NCH 3   
                 CH 2 Cl 
                 H 
                 CH 2   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.231 
                 NCH 3   
                 CH 2 Cl 
                 H 
                 CH 2   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.232 
                 NCH 3   
                 CH 2 Cl 
                 H 
                 CH 2   
                 Cl 
                 OH 
               
               
                 Ia1.233 
                 NCH 3   
                 CH 2 Cl 
                 H 
                 CH 2   
                 Br 
                 OH 
               
               
                 Ia1.234 
                 NCH 3   
                 CH 2 Cl 
                 H 
                 CH 2   
                 NO 2   
                 OH 
               
               
                 Ia1.235 
                 NCH 3   
                 CH 2 Cl 
                 H 
                 CH 2   
                 CHF 2   
                 OH 
               
               
                 Ia1.236 
                 NCH 3   
                 CH 2 Cl 
                 H 
                 CH 2   
                 CF 3   
                 OH 
               
               
                 Ia1.237 
                 NCH 3   
                 CH 2 Cl 
                 H 
                 CH 2   
                 OCH 3   
                 OH 
               
               
                 Ia1.238 
                 NCH 3   
                 CH 2 Cl 
                 H 
                 CH 2   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.239 
                 NCH 3   
                 CH 2 Cl 
                 H 
                 CH 2   
                 OCHF 2   
                 OH 
               
               
                 Ia1.240 
                 NCH 3   
                 CH 2 Cl 
                 H 
                 CH 2   
                 OCF 3   
                 OH 
               
               
                 Ia1.241 
                 NCH 3   
                 CH 2 CH 3   
                 H 
                 CH 2   
                 SCH 3   
                 OH 
               
               
                 Ia1.242 
                 NCH 3   
                 CH 2 CH 3   
                 H 
                 CH 2   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.243 
                 NCH 3   
                 CH 2 CH 3   
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.244 
                 NCH 3   
                 CH 2 CH 3   
                 H 
                 CH 2   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.245 
                 NCH 3   
                 CH 2 CH 3   
                 H 
                 CH 2   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.246 
                 NCH 3   
                 CH 2 CH 3   
                 H 
                 CH 2   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.247 
                 NCH 3   
                 CH 2 CH 3   
                 H 
                 CH 2   
                 Cl 
                 OH 
               
               
                 Ia1.248 
                 NCH 3   
                 CH 2 CH 3   
                 H 
                 CH 2   
                 Br 
                 OH 
               
               
                 Ia1.249 
                 NCH 3   
                 CH 2 CH 3   
                 H 
                 CH 2   
                 NO 2   
                 OH 
               
               
                 Ia1.250 
                 NCH 3   
                 CH 2 CH 3   
                 H 
                 CH 2   
                 CHF 2   
                 OH 
               
               
                 Ia1.251 
                 NCH 3   
                 CH 2 CH 3   
                 H 
                 CH 2   
                 CF 3   
                 OH 
               
               
                 Ia1.252 
                 NCH 3   
                 CH 2 CH 3   
                 H 
                 CH 2   
                 OCH 3   
                 OH 
               
               
                 Ia1.253 
                 NCH 3   
                 CH 2 CH 3   
                 H 
                 CH 2   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.254 
                 NCH 3   
                 CH 2 CH 3   
                 H 
                 CH 2   
                 OCHF 2   
                 OH 
               
               
                 Ia1.255 
                 NCH 3   
                 CH 2 CH 3   
                 H 
                 CH 2   
                 OCF 3   
                 OH 
               
               
                 Ia1.256 
                 NCH 3   
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 SCH 3   
                 OH 
               
               
                 Ia1.257 
                 NCH 3   
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.258 
                 NCH 3   
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.259 
                 NCH 3   
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.260 
                 NCH 3   
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.261 
                 NCH 3   
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.262 
                 NCH 3   
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 Cl 
                 OH 
               
               
                 Ia1.263 
                 NCH 3   
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 Br 
                 OH 
               
               
                 Ia1.264 
                 NCH 3   
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 NO 2   
                 OH 
               
               
                 Ia1.265 
                 NCH 3   
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 CHF 2   
                 OH 
               
               
                 Ia1.266 
                 NCH 3   
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 CF 3   
                 OH 
               
               
                 Ia1.267 
                 NCH 3   
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 OCH 3   
                 OH 
               
               
                 Ia1.268 
                 NCH 3   
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.269 
                 NCH 3   
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 OCHF 2   
                 OH 
               
               
                 Ia1.270 
                 NCH 3   
                 CH 2 CH 3   
                 CH 2 CH 3   
                 CH 2   
                 OCF 3   
                 OH 
               
               
                 Ia1.271 
                 NCH 3   
                 H 
                 H 
                 CH(CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ia1.272 
                 NCH 3   
                 H 
                 H 
                 CH(CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.273 
                 NCH 3   
                 H 
                 H 
                 CH(CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.274 
                 NCH 3   
                 H 
                 H 
                 CH(CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.275 
                 NCH 3   
                 H 
                 H 
                 CH(CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.276 
                 NCH 3   
                 H 
                 H 
                 CH(CH 3 ) 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.277 
                 NCH 3   
                 H 
                 H 
                 CH(CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ia1.278 
                 NCH 3   
                 H 
                 H 
                 CH(CH 3 ) 
                 Br 
                 OH 
               
               
                 Ia1.279 
                 NCH 3   
                 H 
                 H 
                 CH(CH 3 ) 
                 NO 2   
                 OH 
               
               
                 Ia1.280 
                 NCH 3   
                 H 
                 H 
                 CH(CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ia1.281 
                 NCH 3   
                 H 
                 H 
                 CH(CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ia1.282 
                 NCH 3   
                 H 
                 H 
                 CH(CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ia1.283 
                 NCH 3   
                 H 
                 H 
                 CH(CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.284 
                 NCH 3   
                 H 
                 H 
                 CH(CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ia1.285 
                 NCH 3   
                 H 
                 H 
                 CH(CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ia1.286 
                 NCH 3   
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ia1.287 
                 NCH 3   
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.288 
                 NCH 3   
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.289 
                 NCH 3   
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.290 
                 NCH 3   
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.291 
                 NCH 3   
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.292 
                 NCH 3   
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ia1.293 
                 NCH 3   
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 Br 
                 OH 
               
               
                 Ia1.294 
                 NCH 3   
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 NO 2   
                 OH 
               
               
                 Ia1.295 
                 NCH 3   
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ia1.296 
                 NCH 3   
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ia1.297 
                 NCH 3   
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ia1.298 
                 NCH 3   
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.299 
                 NCH 3   
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ia1.300 
                 NCH 3   
                 CH 3   
                 H 
                 CH(CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ia1.301 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ia1.302 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.303 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.304 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.305 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.306 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 SO 2 (CH 2 ) 2 H 3   
                 OH 
               
               
                 Ia1.307 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ia1.308 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 Br 
                 OH 
               
               
                 Ia1.309 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 NO 2   
                 OH 
               
               
                 Ia1.310 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ia1.311 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ia1.312 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ia1.313 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.314 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ia1.315 
                 NCH 3   
                 CH 3   
                 CH 3   
                 CH(CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ia1.316 
                 NCH 3   
                 H 
                 H 
                 C(CH 3 ) 2   
                 SCH 3   
                 OH 
               
               
                 Ia1.317 
                 NCH 3   
                 H 
                 H 
                 C(CH 3 ) 2   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.318 
                 NCH 3   
                 H 
                 H 
                 C(CH 3 ) 2   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.319 
                 NCH 3   
                 H 
                 H 
                 C(CH 3 ) 2   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.320 
                 NCH 3   
                 H 
                 H 
                 C(CH 3 ) 2   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.321 
                 NCH 3   
                 H 
                 H 
                 C(CH 3 ) 2   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.322 
                 NCH 3   
                 H 
                 H 
                 C(CH 3 ) 2   
                 Cl 
                 OH 
               
               
                 Ia1.323 
                 NCH 3   
                 H 
                 H 
                 C(CH 3 ) 2   
                 Br 
                 OH 
               
               
                 Ia1.324 
                 NCH 3   
                 H 
                 H 
                 C(CH 3 ) 2   
                 NO 2   
                 OH 
               
               
                 Ia1.325 
                 NCH 3   
                 H 
                 H 
                 C(CH 3 ) 2   
                 CHF 2   
                 OH 
               
               
                 Ia1.326 
                 NCH 3   
                 H 
                 H 
                 C(CH 3 ) 2   
                 CF 3   
                 OH 
               
               
                 Ia1.327 
                 NCH 3   
                 H 
                 H 
                 C(CH 3 ) 2   
                 OCH 3   
                 OH 
               
               
                 Ia1.328 
                 NCH 3   
                 H 
                 H 
                 C(CH 3 ) 2   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.329 
                 NCH 3   
                 H 
                 H 
                 C(CH 3 ) 2   
                 OCHF 2   
                 OH 
               
               
                 Ia1.330 
                 NCH 3   
                 H 
                 H 
                 C(CH 3 ) 2   
                 OCF 3   
                 OH 
               
               
                 Ia1.331 
                 NCH 3   
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 SCH 3   
                 OH 
               
               
                 Ia1.332 
                 NCH 3   
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.333 
                 NCH 3   
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.334 
                 NCH 3   
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.335 
                 NCH 3   
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.336 
                 NCH 3   
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.337 
                 NCH 3   
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 Cl 
                 OH 
               
               
                 Ia1.338 
                 NCH 3   
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 Br 
                 OH 
               
               
                 Ia1.339 
                 NCH 3   
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 NO 2   
                 OH 
               
               
                 Ia1.340 
                 NCH 3   
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 CHF 2   
                 OH 
               
               
                 Ia1.341 
                 NCH 3   
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 CF 3   
                 OH 
               
               
                 Ia1.342 
                 NCH 3   
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 OCH 3   
                 OH 
               
               
                 Ia1.343 
                 NCH 3   
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.344 
                 NCH 3   
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 OCHF 2   
                 OH 
               
               
                 Ia1.345 
                 NCH 3   
                 CH 3   
                 H 
                 C(CH 3 ) 2   
                 OCF 3   
                 OH 
               
               
                 Ia1.346 
                 NCH 3   
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 SCH 3   
                 OH 
               
               
                 Ia1.347 
                 NCH 3   
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.348 
                 NCH 3   
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.349 
                 NCH 3   
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.350 
                 NCH 3   
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.351 
                 NCH 3   
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.352 
                 NCH 3   
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 Cl 
                 OH 
               
               
                 Ia1.353 
                 NCH 3   
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 Br 
                 OH 
               
               
                 Ia1.354 
                 NCH 3   
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 NO 2   
                 OH 
               
               
                 Ia1.355 
                 NCH 3   
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 CHF 2   
                 OH 
               
               
                 Ia1.356 
                 NCH 3   
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 CF 3   
                 OH 
               
               
                 Ia1.357 
                 NCH 3   
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 OCH 3   
                 OH 
               
               
                 Ia1.358 
                 NCH 3   
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.359 
                 NCH 3   
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 OCHF 2   
                 OH 
               
               
                 Ia1.360 
                 NCH 3   
                 CH 3   
                 CH 3   
                 C(CH 3 ) 2   
                 OCF 3   
                 OH 
               
               
                 Ia1.361 
                 CH 2   
                 H 
                 H 
                 O 
                 SCH 3   
                 OH 
               
               
                 Ia1.362 
                 CH 2   
                 H 
                 H 
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.363 
                 CH 2   
                 H 
                 H 
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.364 
                 CH 2   
                 H 
                 H 
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.365 
                 CH 2   
                 H 
                 H 
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.366 
                 CH 2   
                 H 
                 H 
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.367 
                 CH 2   
                 H 
                 H 
                 O 
                 Cl 
                 OH 
               
               
                 Ia1.368 
                 CH 2   
                 H 
                 H 
                 O 
                 Br 
                 OH 
               
               
                 Ia1.369 
                 CH 2   
                 H 
                 H 
                 O 
                 NO 2   
                 OH 
               
               
                 Ia1.370 
                 CH 2   
                 H 
                 H 
                 O 
                 CHF 2   
                 OH 
               
               
                 Ia1.371 
                 CH 2   
                 H 
                 H 
                 O 
                 CF 3   
                 OH 
               
               
                 Ia1.372 
                 CH 2   
                 H 
                 H 
                 O 
                 OCH 3   
                 OH 
               
               
                 Ia1.373 
                 CH 2   
                 H 
                 H 
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.374 
                 CH 2   
                 H 
                 H 
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ia1.375 
                 CH 2   
                 H 
                 H 
                 O 
                 OCF 3   
                 OH 
               
               
                 Ia1.376 
                 CH 2   
                 CH 3   
                 H 
                 O 
                 SCH 3   
                 OH 
               
               
                 Ia1.377 
                 CH 2   
                 CH 3   
                 H 
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.378 
                 CH 2   
                 CH 3   
                 H 
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.379 
                 CH 2   
                 CH 3   
                 H 
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.380 
                 CH 2   
                 CH 3   
                 H 
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.381 
                 CH 2   
                 CH 3   
                 H 
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.382 
                 CH 2   
                 CH 3   
                 H 
                 O 
                 Cl 
                 OH 
               
               
                 Ia1.383 
                 CH 2   
                 CH 3   
                 H 
                 O 
                 Br 
                 OH 
               
               
                 Ia1.384 
                 CH 2   
                 CH 3   
                 H 
                 O 
                 NO 2   
                 OH 
               
               
                 Ia1.385 
                 CH 2   
                 CH 3   
                 H 
                 O 
                 CHF 2   
                 OH 
               
               
                 Ia1.386 
                 CH 2   
                 CH 3   
                 H 
                 O 
                 CF 3   
                 OH 
               
               
                 Ia1.387 
                 CH 2   
                 CH 3   
                 H 
                 O 
                 OCH 3   
                 OH 
               
               
                 Ia1.388 
                 CH 2   
                 CH 3   
                 H 
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.389 
                 CH 2   
                 CH 3   
                 H 
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ia1.390 
                 CH 2   
                 CH 3   
                 H 
                 O 
                 OCF 3   
                 OH 
               
               
                 Ia1.391 
                 CH 2   
                 CH 3   
                 CH 3   
                 O 
                 SCH 3   
                 OH 
               
               
                 Ia1.392 
                 CH 2   
                 CH 3   
                 CH 3   
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.393 
                 CH 2   
                 CH 3   
                 CH 3   
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.394 
                 CH 2   
                 CH 3   
                 CH 3   
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.395 
                 CH 2   
                 CH 3   
                 CH 3   
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.396 
                 CH 2   
                 CH 3   
                 CH 3   
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.397 
                 CH 2   
                 CH 3   
                 CH 3   
                 O 
                 Cl 
                 OH 
               
               
                 Ia1.398 
                 CH 2   
                 CH 3   
                 CH 3   
                 O 
                 Br 
                 OH 
               
               
                 Ia1.399 
                 CH 2   
                 CH 3   
                 CH 3   
                 O 
                 NO 2   
                 OH 
               
               
                 Ia1.400 
                 CH 2   
                 CH 3   
                 CH 3   
                 O 
                 CHF 2   
                 OH 
               
               
                 Ia1.401 
                 CH 2   
                 CH 3   
                 CH 3   
                 O 
                 CF 3   
                 OH 
               
               
                 Ia1.402 
                 CH 2   
                 CH 3   
                 CH 3   
                 O 
                 OCH 3   
                 OH 
               
               
                 Ia1.403 
                 CH 2   
                 CH 3   
                 CH 3   
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.404 
                 CH 2   
                 CH 3   
                 CH 3   
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ia1.405 
                 CH 2   
                 CH 3   
                 CH 3   
                 O 
                 OCF 3   
                 OH 
               
               
                 Ia1.406 
                 CH 2   
                 H 
                 H 
                 S 
                 SCH 3   
                 OH 
               
               
                 Ia1.407 
                 CH 2   
                 H 
                 H 
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.408 
                 CH 2   
                 H 
                 H 
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.409 
                 CH 2   
                 H 
                 H 
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.410 
                 CH 2   
                 H 
                 H 
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.411 
                 CH 2   
                 H 
                 H 
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.412 
                 CH 2   
                 H 
                 H 
                 S 
                 Cl 
                 OH 
               
               
                 Ia1.413 
                 CH 2   
                 H 
                 H 
                 S 
                 Br 
                 OH 
               
               
                 Ia1.414 
                 CH 2   
                 H 
                 H 
                 S 
                 NO 3   
                 OH 
               
               
                 Ia1.415 
                 CH 2   
                 H 
                 H 
                 S 
                 CHF 2   
                 OH 
               
               
                 Ia1.416 
                 CH 2   
                 H 
                 H 
                 S 
                 CF 3   
                 OH 
               
               
                 Ia1.417 
                 CH 2   
                 H 
                 H 
                 S 
                 OCH 3   
                 OH 
               
               
                 Ia1.418 
                 CH 2   
                 H 
                 H 
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.419 
                 CH 2   
                 H 
                 H 
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ia1.420 
                 CH 2   
                 H 
                 H 
                 S 
                 OCF 3   
                 OH 
               
               
                 Ia1.421 
                 CH 2   
                 CH 3   
                 H 
                 S 
                 SCH 3   
                 OH 
               
               
                 Ia1.422 
                 CH 2   
                 CH 3   
                 H 
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.423 
                 CH 2   
                 CH 3   
                 H 
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.424 
                 CH 2   
                 CH 3   
                 H 
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.425 
                 CH 2   
                 CH 3   
                 H 
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.426 
                 CH 2   
                 CH 3   
                 H 
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.427 
                 CH 2   
                 CH 3   
                 H 
                 S 
                 Cl 
                 OH 
               
               
                 Ia1.428 
                 CH 2   
                 CH 3   
                 H 
                 S 
                 Br 
                 OH 
               
               
                 Ia1.429 
                 CH 2   
                 CH 3   
                 H 
                 S 
                 NO 2   
                 OH 
               
               
                 Ia1.430 
                 CH 2   
                 CH 3   
                 H 
                 S 
                 CHF 2   
                 OH 
               
               
                 Ia1.431 
                 CH 2   
                 CH 3   
                 H 
                 S 
                 CF 3   
                 OH 
               
               
                 Ia1.432 
                 CH 2   
                 CH 3   
                 H 
                 S 
                 OCH 3   
                 OH 
               
               
                 Ia1.433 
                 CH 2   
                 CH 3   
                 H 
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.434 
                 CH 2   
                 CH 3   
                 H 
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ia1.435 
                 CH 2   
                 CH 3   
                 H 
                 S 
                 OCF 3   
                 OH 
               
               
                 Ia1.436 
                 CH 2   
                 CH 3   
                 CH 3   
                 S 
                 SCH 3   
                 OH 
               
               
                 Ia1.437 
                 CH 2   
                 CH 3   
                 CH 3   
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.438 
                 CH 2   
                 CH 3   
                 CH 3   
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.439 
                 CH 2   
                 CH 3   
                 CH 3   
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.440 
                 CH 2   
                 CH 3   
                 CH 3   
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.441 
                 CH 2   
                 CH 3   
                 CH 3   
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.442 
                 CH 2   
                 CH 3   
                 CH 3   
                 S 
                 Cl 
                 OH 
               
               
                 Ia1.443 
                 CH 2   
                 CH 3   
                 CH 3   
                 S 
                 Br 
                 OH 
               
               
                 Ia1.444 
                 CH 2   
                 CH 3   
                 CH 3   
                 S 
                 NO 2   
                 OH 
               
               
                 Ia1.445 
                 CH 2   
                 CH 3   
                 CH 3   
                 S 
                 CHF 2   
                 OH 
               
               
                 Ia1.446 
                 CH 2   
                 CH 3   
                 CH 3   
                 S 
                 CF 3   
                 OH 
               
               
                 Ia1.447 
                 CH 2   
                 CH 3   
                 CH 3   
                 S 
                 OCH 3   
                 OH 
               
               
                 Ia1.448 
                 CH 2   
                 CH 3   
                 CH 3   
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.449 
                 CH 2   
                 CH 3   
                 CH 3   
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ia1.450 
                 CH 2   
                 CH 3   
                 CH 3   
                 S 
                 OCF 3   
                 OH 
               
               
                 Ia1.451 
                 CH 2   
                 H 
                 H 
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ia1.452 
                 CH 2   
                 H 
                 H 
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.453 
                 CH 2   
                 H 
                 H 
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.454 
                 CH 2   
                 H 
                 H 
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.455 
                 CH 2   
                 H 
                 H 
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.456 
                 CH 2   
                 H 
                 H 
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.457 
                 CH 2   
                 H 
                 H 
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ia1.458 
                 CH 2   
                 H 
                 H 
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ia1.459 
                 CH 2   
                 H 
                 H 
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ia1.460 
                 CH 2   
                 H 
                 H 
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ia1.461 
                 CH 2   
                 H 
                 H 
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ia1.462 
                 CH 2   
                 H 
                 H 
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ia1.463 
                 CH 2   
                 H 
                 H 
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.464 
                 CH 2   
                 H 
                 H 
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ia1.465 
                 CH 2   
                 H 
                 H 
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ia1.466 
                 CH 2   
                 CH 3   
                 H 
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ia1.467 
                 CH 2   
                 CH 3   
                 H 
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.468 
                 CH 2   
                 CH 3   
                 H 
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.469 
                 CH 2   
                 CH 3   
                 H 
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.470 
                 CH 2   
                 CH 3   
                 H 
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.471 
                 CH 2   
                 CH 3   
                 H 
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.472 
                 CH 2   
                 CH 3   
                 H 
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ia1.473 
                 CH 2   
                 CH 3   
                 H 
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ia1.474 
                 CH 2   
                 CH 3   
                 H 
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ia1.475 
                 CH 2   
                 CH 3   
                 H 
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ia1.476 
                 CH 2   
                 CH 3   
                 H 
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ia1.477 
                 CH 2   
                 CH 3   
                 H 
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ia1.478 
                 CH 2   
                 CH 3   
                 H 
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.479 
                 CH 2   
                 CH 3   
                 H 
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ia1.480 
                 CH 2   
                 CH 3   
                 H 
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ia1.481 
                 CH 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ia1.482 
                 CH 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.483 
                 CH 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.484 
                 CH 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.485 
                 CH 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.486 
                 CH 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.487 
                 CH 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ia1.488 
                 CH 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ia1.489 
                 CH 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ia1.490 
                 CH 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ia1.491 
                 CH 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ia1.492 
                 CH 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ia1.493 
                 CH 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.494 
                 CH 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ia1.495 
                 CH 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ia1.496 
                 CHCH 3   
                 H 
                 H 
                 O 
                 SCH 3   
                 OH 
               
               
                 Ia1.497 
                 CHCH 3   
                 H 
                 H 
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.498 
                 CHCH 3   
                 H 
                 H 
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.499 
                 CHCH 3   
                 H 
                 H 
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.500 
                 CHCH 3   
                 H 
                 H 
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.501 
                 CHCH 3   
                 H 
                 H 
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.502 
                 CHCH 3   
                 H 
                 H 
                 O 
                 Cl 
                 OH 
               
               
                 Ia1.503 
                 CHCH 3   
                 H 
                 H 
                 O 
                 Br 
                 OH 
               
               
                 Ia1.504 
                 CHCH 3   
                 H 
                 H 
                 O 
                 NO 2   
                 OH 
               
               
                 Ia1.505 
                 CHCH 3   
                 H 
                 H 
                 O 
                 CHF 2   
                 OH 
               
               
                 Ia1.506 
                 CHCH 3   
                 H 
                 H 
                 O 
                 CF 3   
                 OH 
               
               
                 Ia1.507 
                 CHCH 3   
                 H 
                 H 
                 O 
                 OCH 3   
                 OH 
               
               
                 Ia1.508 
                 CHCH 3   
                 H 
                 H 
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.509 
                 CHCH 3   
                 H 
                 H 
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ia1.510 
                 CHCH 3   
                 H 
                 H 
                 O 
                 OCF 3   
                 OH 
               
               
                 Ia1.511 
                 CHCH 3   
                 CH 3   
                 H 
                 O 
                 SCH 3   
                 OH 
               
               
                 Ia1.512 
                 CHCH 3   
                 CH 3   
                 H 
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.513 
                 CHCH 3   
                 CH 3   
                 H 
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.514 
                 CHCH 3   
                 CH 3   
                 H 
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.515 
                 CHCH 3   
                 CH 3   
                 H 
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.516 
                 CHCH 3   
                 CH 3   
                 H 
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.517 
                 CHCH 3   
                 CH 3   
                 H 
                 O 
                 Cl 
                 OH 
               
               
                 Ia1.518 
                 CHCH 3   
                 CH 3   
                 H 
                 O 
                 Br 
                 OH 
               
               
                 Ia1.519 
                 CHCH 3   
                 CH 3   
                 H 
                 O 
                 NO 2   
                 OH 
               
               
                 Ia1.520 
                 CHCH 3   
                 CH 3   
                 H 
                 O 
                 CHF 2   
                 OH 
               
               
                 Ia1.521 
                 CHCH 3   
                 CH 3   
                 H 
                 O 
                 CF 3   
                 OH 
               
               
                 Ia1.522 
                 CHCH 3   
                 CH 3   
                 H 
                 O 
                 OCH 3   
                 OH 
               
               
                 Ia1.523 
                 CHCH 3   
                 CH 3   
                 H 
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.524 
                 CHCH 3   
                 CH 3   
                 H 
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ia1.525 
                 CHCH 3   
                 CH 3   
                 H 
                 O 
                 OCF 3   
                 OH 
               
               
                 Ia1.526 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 O 
                 SCH 3   
                 OH 
               
               
                 Ia1.527 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.528 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.529 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.530 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.531 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.532 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 O 
                 Cl 
                 OH 
               
               
                 Ia1.533 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 O 
                 Br 
                 OH 
               
               
                 Ia1.534 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 O 
                 NO 2   
                 OH 
               
               
                 Ia1.535 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 O 
                 CHF 2   
                 OH 
               
               
                 Ia1.536 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 O 
                 CF 3   
                 OH 
               
               
                 Ia1.537 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 O 
                 OCH 3   
                 OH 
               
               
                 Ia1.538 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.539 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ia1.540 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 O 
                 OCF 3   
                 OH 
               
               
                 Ia1.541 
                 CHCH 3   
                 H 
                 H 
                 S 
                 SCH 3   
                 OH 
               
               
                 Ia1.542 
                 CHCH 3   
                 H 
                 H 
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.543 
                 CHCH 3   
                 H 
                 H 
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.544 
                 CHCH 3   
                 H 
                 H 
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.545 
                 CHCH 3   
                 H 
                 H 
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.546 
                 CHCH 3   
                 H 
                 H 
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.547 
                 CHCH 3   
                 H 
                 H 
                 S 
                 Cl 
                 OH 
               
               
                 Ia1.548 
                 CHCH 3   
                 H 
                 H 
                 S 
                 Br 
                 OH 
               
               
                 Ia1.549 
                 CHCH 3   
                 H 
                 H 
                 S 
                 NO 2   
                 OH 
               
               
                 Ia1.550 
                 CHCH 3   
                 H 
                 H 
                 S 
                 CHF 2   
                 OH 
               
               
                 Ia1.551 
                 CHCH 3   
                 H 
                 H 
                 S 
                 CF 3   
                 OH 
               
               
                 Ia1.552 
                 CHCH 3   
                 H 
                 H 
                 S 
                 OCH 3   
                 OH 
               
               
                 Ia1.553 
                 CHCH 3   
                 H 
                 H 
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.554 
                 CHCH 3   
                 H 
                 H 
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ia1.555 
                 CHCH 3   
                 H 
                 H 
                 S 
                 OCF 3   
                 OH 
               
               
                 Ia1.556 
                 CHCH 3   
                 CH 3   
                 H 
                 S 
                 SCH 3   
                 OH 
               
               
                 Ia1.557 
                 CHCH 3   
                 CH 3   
                 H 
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.558 
                 CHCH 3   
                 CH 3   
                 H 
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.559 
                 CHCH 3   
                 CH 3   
                 H 
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.560 
                 CHCH 3   
                 CH 3   
                 H 
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.561 
                 CHCH 3   
                 CH 3   
                 H 
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.562 
                 CHCH 3   
                 CH 3   
                 H 
                 S 
                 Cl 
                 OH 
               
               
                 Ia1.563 
                 CHCH 3   
                 CH 3   
                 H 
                 S 
                 Br 
                 OH 
               
               
                 Ia1.564 
                 CHCH 3   
                 CH 3   
                 H 
                 S 
                 NO 2   
                 OH 
               
               
                 Ia1.565 
                 CHCH 3   
                 CH 3   
                 H 
                 S 
                 CHF 2   
                 OH 
               
               
                 Ia1.566 
                 CHCH 3   
                 CH 3   
                 H 
                 S 
                 CF 3   
                 OH 
               
               
                 Ia1.567 
                 CHCH 3   
                 CH 3   
                 H 
                 S 
                 OCH 3   
                 OH 
               
               
                 Ia1.568 
                 CHCH 3   
                 CH 3   
                 H 
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.569 
                 CHCH 3   
                 CH 3   
                 H 
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ia1.570 
                 CHCH 3   
                 CH 3   
                 H 
                 S 
                 OCF 3   
                 OH 
               
               
                 Ia1.571 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 S 
                 SCH 3   
                 OH 
               
               
                 Ia1.572 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.573 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.574 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.575 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.576 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.577 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 S 
                 Cl 
                 OH 
               
               
                 Ia1.578 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 S 
                 Br 
                 OH 
               
               
                 Ia1.579 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 S 
                 NO 2   
                 OH 
               
               
                 Ia1.580 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 S 
                 CHF 2   
                 OH 
               
               
                 Ia1.581 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 S 
                 CF 3   
                 OH 
               
               
                 Ia1.582 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 S 
                 OCH 3   
                 OH 
               
               
                 Ia1.583 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.584 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ia1.585 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 S 
                 OCF 3   
                 OH 
               
               
                 Ia1.586 
                 CHCH 3   
                 H 
                 H 
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ia1.587 
                 CHCH 3   
                 H 
                 H 
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.588 
                 CHCH 3   
                 H 
                 H 
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.589 
                 CHCH 3   
                 H 
                 H 
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.590 
                 CHCH 3   
                 H 
                 H 
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.591 
                 CHCH 3   
                 H 
                 H 
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.592 
                 CHCH 3   
                 H 
                 H 
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ia1.593 
                 CHCH 3   
                 H 
                 H 
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ia1.594 
                 CHCH 3   
                 H 
                 H 
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ia1.595 
                 CHCH 3   
                 H 
                 H 
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ia1.596 
                 CHCH 3   
                 H 
                 H 
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ia1.597 
                 CHCH 3   
                 H 
                 H 
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ia1.598 
                 CHCH 3   
                 H 
                 H 
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.599 
                 CHCH 3   
                 H 
                 H 
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ia1.600 
                 CHCH 3   
                 H 
                 H 
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ia1.601 
                 CHCH 3   
                 CH 3   
                 H 
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ia1.602 
                 CHCH 3   
                 CH 3   
                 H 
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.603 
                 CHCH 3   
                 CH 3   
                 H 
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.604 
                 CHCH 3   
                 CH 3   
                 H 
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.605 
                 CHCH 3   
                 CH 3   
                 H 
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.606 
                 CHCH 3   
                 CH 3   
                 H 
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.607 
                 CHCH 3   
                 CH 3   
                 H 
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ia1.608 
                 CHCH 3   
                 CH 3   
                 H 
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ia1.609 
                 CHCH 3   
                 CH 3   
                 H 
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ia1.610 
                 CHCH 3   
                 CH 3   
                 H 
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ia1.611 
                 CHCH 3   
                 CH 3   
                 H 
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ia1.612 
                 CHCH 3   
                 CH 3   
                 H 
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ia1.613 
                 CHCH 3   
                 CH 3   
                 H 
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.614 
                 CHCH 3   
                 CH 3   
                 H 
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ia1.615 
                 CHCH 3   
                 CH 3   
                 H 
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ia1.616 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ia1.617 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.618 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.619 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.620 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.621 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.622 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ia1.623 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ia1.624 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ia1.625 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ia1.626 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ia1.627 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ia1.628 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.629 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ia1.630 
                 CHCH 3   
                 CH 3   
                 CH 3   
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ia1.631 
                 C(CH 3 ) 2   
                 H 
                 H 
                 O 
                 SCH 3   
                 OH 
               
               
                 Ia1.632 
                 C(CH 3 ) 2   
                 H 
                 H 
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.633 
                 C(CH 3 ) 2   
                 H 
                 H 
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.634 
                 C(CH 3 ) 2   
                 H 
                 H 
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.635 
                 C(CH 3 ) 2   
                 H 
                 H 
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.636 
                 C(CH 3 ) 2   
                 H 
                 H 
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.637 
                 C(CH 3 ) 2   
                 H 
                 H 
                 O 
                 Cl 
                 OH 
               
               
                 Ia1.638 
                 C(CH 3 ) 2   
                 H 
                 H 
                 O 
                 Br 
                 OH 
               
               
                 Ia1.639 
                 C(CH 3 ) 2   
                 H 
                 H 
                 O 
                 NO 2   
                 OH 
               
               
                 Ia1.640 
                 C(CH 3 ) 2   
                 H 
                 H 
                 O 
                 CHF 2   
                 OH 
               
               
                 Ia1.641 
                 C(CH 3 ) 2   
                 H 
                 H 
                 O 
                 CF 3   
                 OH 
               
               
                 Ia1.642 
                 C(CH 3 ) 2   
                 H 
                 H 
                 O 
                 OCH 3   
                 OH 
               
               
                 Ia1.643 
                 C(CH 3 ) 2   
                 H 
                 H 
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.644 
                 C(CH 3 ) 2   
                 H 
                 H 
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ia1.645 
                 C(CH 3 ) 2   
                 H 
                 H 
                 O 
                 OCF 3   
                 OH 
               
               
                 Ia1.646 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 O 
                 SCH 3   
                 OH 
               
               
                 Ia1.647 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.648 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.649 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.650 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.651 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.652 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 O 
                 Cl 
                 OH 
               
               
                 Ia1.653 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 O 
                 Br 
                 OH 
               
               
                 Ia1.654 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 O 
                 NO 2   
                 OH 
               
               
                 Ia1.655 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 O 
                 CHF 2   
                 OH 
               
               
                 Ia1.656 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 O 
                 CF 3   
                 OH 
               
               
                 Ia1.657 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 O 
                 OCH 3   
                 OH 
               
               
                 Ia1.658 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.659 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ia1.660 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 O 
                 OCF 3   
                 OH 
               
               
                 Ia1.661 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 O 
                 SCH 3   
                 OH 
               
               
                 Ia1.662 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.663 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.664 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.665 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.666 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.667 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 O 
                 Cl 
                 OH 
               
               
                 Ia1.668 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 O 
                 Br 
                 OH 
               
               
                 Ia1.669 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 O 
                 NO 2   
                 OH 
               
               
                 Ia1.670 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 O 
                 CHF 2   
                 OH 
               
               
                 Ia1.671 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 O 
                 CF 3   
                 OH 
               
               
                 Ia1.672 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 O 
                 OCH 3   
                 OH 
               
               
                 Ia1.673 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.674 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ia1.675 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 O 
                 OCF 3   
                 OH 
               
               
                 Ia1.676 
                 C(CH 3 ) 2   
                 H 
                 H 
                 S 
                 SCH 3   
                 OH 
               
               
                 Ia1.677 
                 C(CH 3 ) 2   
                 H 
                 H 
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.678 
                 C(CH 3 ) 2   
                 H 
                 H 
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.679 
                 C(CH 3 ) 2   
                 H 
                 H 
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.680 
                 C(CH 3 ) 2   
                 H 
                 H 
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.681 
                 C(CH 3 ) 2   
                 H 
                 H 
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.682 
                 C(CH 3 ) 2   
                 H 
                 H 
                 S 
                 Cl 
                 OH 
               
               
                 Ia1.683 
                 C(CH 3 ) 2   
                 H 
                 H 
                 S 
                 Br 
                 OH 
               
               
                 Ia1.684 
                 C(CH 3 ) 2   
                 H 
                 H 
                 S 
                 NO 2   
                 OH 
               
               
                 Ia1.685 
                 C(CH 3 ) 2   
                 H 
                 H 
                 S 
                 CHF 2   
                 OH 
               
               
                 Ia1.686 
                 C(CH 3 ) 2   
                 H 
                 H 
                 S 
                 CF 3   
                 OH 
               
               
                 Ia1.687 
                 C(CH 3 ) 2   
                 H 
                 H 
                 S 
                 OCH 3   
                 OH 
               
               
                 Ia1.688 
                 C(CH 3 ) 2   
                 H 
                 H 
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.689 
                 C(CH 3 ) 2   
                 H 
                 H 
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ia1.690 
                 C(CH 3 ) 2   
                 H 
                 H 
                 S 
                 OCF 3   
                 OH 
               
               
                 Ia1.691 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 S 
                 SCH 3   
                 OH 
               
               
                 Ia1.692 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.693 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.694 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.695 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.696 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.697 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 S 
                 Cl 
                 OH 
               
               
                 Ia1.698 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 S 
                 Br 
                 OH 
               
               
                 Ia1.699 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 S 
                 NO 2   
                 OH 
               
               
                 Ia1.700 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 S 
                 CHF 2   
                 OH 
               
               
                 Ia1.701 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 S 
                 CF 3   
                 OH 
               
               
                 Ia1.702 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 S 
                 OCH 3   
                 OH 
               
               
                 Ia1.703 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.704 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ia1.705 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 S 
                 OCF 3   
                 OH 
               
               
                 Ia1.706 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 S 
                 SCH 3   
                 OH 
               
               
                 Ia1.707 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.708 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.709 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.710 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.711 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.712 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 S 
                 Cl 
                 OH 
               
               
                 Ia1.713 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 S 
                 Br 
                 OH 
               
               
                 Ia1.714 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 S 
                 NO 2   
                 OH 
               
               
                 Ia1.715 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 S 
                 CHF 2   
                 OH 
               
               
                 Ia1.716 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 S 
                 CF 3   
                 OH 
               
               
                 Ia1.717 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 S 
                 OCH 3   
                 OH 
               
               
                 Ia1.718 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.719 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ia1.720 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 S 
                 OCF 3   
                 OH 
               
               
                 Ia1.721 
                 C(CH 3 ) 2   
                 H 
                 H 
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ia1.722 
                 C(CH 3 ) 2   
                 H 
                 H 
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.723 
                 C(CH 3 ) 2   
                 H 
                 H 
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.724 
                 C(CH 3 ) 2   
                 H 
                 H 
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.725 
                 C(CH 3 ) 2   
                 H 
                 H 
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.726 
                 C(CH 3 ) 2   
                 H 
                 H 
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.727 
                 C(CH 3 ) 2   
                 H 
                 H 
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ia1.728 
                 C(CH 3 ) 2   
                 H 
                 H 
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ia1.729 
                 C(CH 3 ) 2   
                 H 
                 H 
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ia1.730 
                 C(CH 3 ) 2   
                 H 
                 H 
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ia1.731 
                 C(CH 3 ) 2   
                 H 
                 H 
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ia1.732 
                 C(CH 3 ) 2   
                 H 
                 H 
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ia1.733 
                 C(CH 3 ) 2   
                 H 
                 H 
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.734 
                 C(CH 3 ) 2   
                 H 
                 H 
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ia1.735 
                 C(CH 3 ) 2   
                 H 
                 H 
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ia1.736 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ia1.737 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.738 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.739 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.740 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.741 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.742 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ia1.743 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ia1.744 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ia1.745 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ia1.746 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ia1.747 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ia1.748 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.749 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ia1.750 
                 C(CH 3 ) 2   
                 CH 3   
                 H 
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ia1.751 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ia1.752 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ia1.753 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ia1.754 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ia1.755 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ia1.756 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ia1.757 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ia1.758 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ia1.759 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ia1.760 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ia1.761 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ia1.762 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ia1.763 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ia1.764 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ia1.765 
                 C(CH 3 ) 2   
                 CH 3   
                 CH 3   
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                   
               
            
           
         
       
     
     Most particular preference is also given to the compounds of the formula Ia2, in particular to the compounds Ia2.1, to Ia2.765 which differ from the corresponding compounds Ia1.1 to Ia1.765 in that R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ia3, in particular to the compounds Ia3.1 to Ia3.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 13  is cyclopentyl.                    
     Most particular preference is also given to the compounds of the formula Ia4, in particular to the compounds Ia4.1 to Ia4.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 13  is cyclopentyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ia5, in particular to the compounds Ia5.1 to Ia5.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 13  is cyclohexyl.                    
     Most particular preference is also given to the compounds of the formula Ia6, in particular to the compounds Ia6.1 to Ia6.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 13  is cyclohexyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ia7, in particular to the compounds Ia7.1 to Ia7.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 13  is 2-norbornyl.                    
     Most particular preference is also given to the compounds of the formula Ia8, in particular to the compounds Ia8.1 to Ia8.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 13  is 2-norbornyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ia9, in particular to the compounds Ia9.1 to Ia9.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 13  is 2-adamantyl.                    
     Most particular preference is also given to the compounds of the formula Ia10, in particular to the compounds Ia10.1 to Ia10.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 13  is 2-adamantyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ia11, in particular to the compounds Ia11.1 to Ia11.765 which differ from the corresponding compounds Ia1.1 to Ia1.765 in that R 1  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ia12, in particular to the compounds Ia12.1 to Ia12.765 which differ from the corresponding compounds Ia1.1 to Ia1.765 in that R 1  is methyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ia13, in particular to the compounds Ia13.1 to Ia13.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 1  is methyl and R 13  is cyclopentyl.                    
     Most particular preference is also given to the compounds of the formula Ia14, in particular to the compounds Ia14.1 to Ia14.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 1  is methyl, R 13  is cyclopentyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ia15, in particular to the compounds Ia15.1 to Ia15.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 1  is methyl and R 13  is cyclohexyl.                    
     Most particular preference is also given to the compounds of the formula Ia16, in particular to the compounds Ia16.1 to Ia16.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 1  is methyl, R 13  is cyclohexyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ia17, in particular to the compounds Ia17.1 to Ia17.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 1  is methyl and R 13  is 2-norbornyl.                    
     Most particular preference is also given to the compounds of the formula Ia18, in particular to the compounds Ia18.1 to Ia18.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 1  is methyl, R 12  is 2-norbornyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ia19, in particular to the compounds Ia19.1 to Ia19.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 1  is methyl and R 13  is 2-adamantyl.                    
     Most particular preference is also given to the compounds of the formula Ia20, in particular to the compounds Ia20.1 to Ia20.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 1  is methyl, R 13  is 2-adamantyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ia21, in particular to the compounds Ia21.1 to Ia21.765 which differ from the corresponding compounds Ia1.1 to Ia1.765 in that R 1  is methoxy.                    
     Most particular preference is also given to the compounds of the formula Ia22, in particular to the compounds Ia22.1 to Ia22.765 which differ from the corresponding compounds Ia1.1 to Ia1.765 in that R 1  is methoxy and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ia23, in particular to the compounds Ia23.1 to Ia23.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 1  is methoxy and R 13  is cyclopentyl.                    
     Most particuiar preference is also given to the compounds of the formula Ia24, in particular to the compounds Ia24.1 to Ia24.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 1  is methoxy, R 13  is cyclopentyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ia25, in particular to the compounds Ia25.1 to Ia25.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 1  is methoxy and R 13  is cyclohexyl.                    
     Most particular preference is also given to the compounds of the formula Ia26, in particular to the compounds Ia26.1 to Ia26.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 1  is methoxy, R 13  is cyclohexyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ia27, in particular to the compounds Ia27.1 to Ia27.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 1  is methoxy and R 13  is 2-norbornyl.                    
     Most particular preference is also given to the compounds of the formula Ia28, in particular to the compounds Ia28.1 to Ia28.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 1  is methoxy, R 13  is norbornyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ia29, in particular to the compounds Ia29.1 to Ia29.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 1  is methoxy and R 13  is 2-adamantyl.                    
     Most particular preference is also given to the compounds of the formula Ia30, in particular to the compounds Ia30.1 to Ia30.765 which differ from the compounds Ia1.1 to Ia1.765 in that R 1  is methoxy, R 13  is 2-adamantyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ib1 (=I where R 1 =Cl, R 3  and R 9  or R 3  and R 11  together form a bond, R 13 =cyclo-C 3 H 5  and R 5  and R 14 =H), in particular to the compounds Ib1.1 to Ib1.420 of Table 2 where the radical definitions X, Y and R 1  to R 14  are of particular importance for the compounds according to the invention not only in combination with one another but also in each case on their own.                    
     
       
         
           
               
               
               
               
               
               
             
               
                   
                 TABLE 2 
               
               
                   
                   
               
               
                   
                 X 
                 R 2   
                 Y 
                 R 4   
                 R 12   
               
               
                   
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
               
            
               
                 Ib1.1 
                 O 
                 H 
                 CH 
                 SCH 3   
                 OH 
               
               
                 Ib1.2 
                 O 
                 H 
                 CH 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.3 
                 O 
                 H 
                 CH 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.4 
                 O 
                 H 
                 CH 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.5 
                 O 
                 H 
                 CH 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.6 
                 O 
                 H 
                 CH 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.7 
                 O 
                 H 
                 CH 
                 Cl 
                 OH 
               
               
                 Ib1.8 
                 O 
                 H 
                 CH 
                 Br 
                 OH 
               
               
                 Ib1.9 
                 O 
                 H 
                 CH 
                 NO 2   
                 OH 
               
               
                 Ib1.10 
                 O 
                 H 
                 CH 
                 CHF 2   
                 OH 
               
               
                 Ib1.11 
                 O 
                 H 
                 CH 
                 CF 3   
                 OH 
               
               
                 Ib1.12 
                 O 
                 H 
                 CH 
                 OCH 3   
                 OH 
               
               
                 Ib1.13 
                 O 
                 H 
                 CH 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.14 
                 O 
                 H 
                 CH 
                 OCHF 2   
                 OH 
               
               
                 Ib1.15 
                 O 
                 H 
                 CH 
                 OCF 3   
                 OH 
               
               
                 Ib1.16 
                 O 
                 CH 3   
                 CH 
                 SCH 3   
                 OH 
               
               
                 Ib1.17 
                 O 
                 CH 3   
                 CH 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.18 
                 O 
                 CH 3   
                 CH 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.19 
                 O 
                 CH 3   
                 CH 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.20 
                 O 
                 CH 3   
                 CH 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.21 
                 O 
                 CH 3   
                 CH 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.22 
                 O 
                 CH 3   
                 CH 
                 Cl 
                 OH 
               
               
                 Ib1.23 
                 O 
                 CH 3   
                 CH 
                 Br 
                 OH 
               
               
                 Ib1.24 
                 O 
                 CH 3   
                 CH 
                 NO 2   
                 OH 
               
               
                 Ib1.25 
                 O 
                 CH 3   
                 CH 
                 CHF 2   
                 OH 
               
               
                 Ib1.26 
                 O 
                 CH 3   
                 CH 
                 CF 3   
                 OH 
               
               
                 Ib1.27 
                 O 
                 CH 3   
                 CH 
                 OCH 3   
                 OH 
               
               
                 Ib1.28 
                 O 
                 CH 3   
                 CH 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.29 
                 O 
                 CH 3   
                 CH 
                 OCHF 2   
                 OH 
               
               
                 Ib1.30 
                 O 
                 CH 3   
                 CH 
                 OCF 3   
                 OH 
               
               
                 Ib1.31 
                 O 
                 CH 2 CH 3   
                 CH 
                 SCH 3   
                 OH 
               
               
                 Ib1.32 
                 O 
                 CH 2 CH 3   
                 CH 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.33 
                 O 
                 CH 2 CH 3   
                 CH 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.34 
                 O 
                 CH 2 CH 3   
                 CH 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.35 
                 O 
                 CH 2 CH 3   
                 CH 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.36 
                 O 
                 CH 2 CH 3   
                 CH 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.37 
                 O 
                 CH 2 CH 3   
                 CH 
                 Cl 
                 OH 
               
               
                 Ib1.38 
                 O 
                 CH 2 CH 3   
                 CH 
                 Br 
                 OH 
               
               
                 Ib1.39 
                 O 
                 CH 2 CH 3   
                 CH 
                 NO 2   
                 OH 
               
               
                 Ib1.40 
                 O 
                 CH 2 CH 3   
                 CH 
                 CHF 2   
                 OH 
               
               
                 Ib1.41 
                 O 
                 CH 2 CH 3   
                 CH 
                 CF 3   
                 OH 
               
               
                 Ib1.42 
                 O 
                 CH 2 CH 3   
                 CH 
                 OCH 3   
                 OH 
               
               
                 Ib1.43 
                 O 
                 CH 2 CH 3   
                 CH 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.44 
                 O 
                 CH 2 CH 3   
                 CH 
                 OCHF 2   
                 OH 
               
               
                 Ib1.45 
                 O 
                 CH 2 CH 3   
                 CH 
                 OCF 3   
                 OH 
               
               
                 Ib1.46 
                 O 
                 CH 2 Cl 
                 CH 
                 SCH 3   
                 OH 
               
               
                 Ib1.47 
                 O 
                 CH 2 Cl 
                 CH 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.48 
                 O 
                 CH 2 Cl 
                 CH 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.49 
                 O 
                 CH 2 Cl 
                 CH 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.50 
                 O 
                 CH 2 Cl 
                 CH 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.51 
                 O 
                 CH 2 Cl 
                 CH 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.52 
                 O 
                 CH 2 Cl 
                 CH 
                 Cl 
                 OH 
               
               
                 Ib1.53 
                 O 
                 CH 2 Cl 
                 CH 
                 Br 
                 OH 
               
               
                 Ib1.54 
                 O 
                 CH 2 Cl 
                 CH 
                 NO 2   
                 OH 
               
               
                 Ib1.55 
                 O 
                 CH 2 Cl 
                 CH 
                 CHF 2   
                 OH 
               
               
                 Ib1.56 
                 O 
                 CH 2 Cl 
                 CH 
                 CF 3   
                 OH 
               
               
                 Ib1.57 
                 O 
                 CH 2 Cl 
                 CH 
                 OCH 3   
                 OH 
               
               
                 Ib1.58 
                 O 
                 CH 2 Cl 
                 CH 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.59 
                 O 
                 CH 2 Cl 
                 CH 
                 OCHF 2   
                 OH 
               
               
                 Ib1.60 
                 O 
                 CH 2 Cl 
                 CH 
                 OCF 3   
                 OH 
               
               
                 Ib1.61 
                 O 
                 H 
                 C(CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ib1.62 
                 O 
                 H 
                 C(CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.63 
                 O 
                 H 
                 C(CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.64 
                 O 
                 H 
                 C(CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.65 
                 O 
                 H 
                 C(CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.66 
                 O 
                 H 
                 C(CH 3 ) 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.67 
                 O 
                 H 
                 C(CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ib1.68 
                 O 
                 H 
                 C(CH 3 ) 
                 Br 
                 OH 
               
               
                 Ib1.69 
                 O 
                 H 
                 C(CH 3 ) 
                 NO 2   
                 OH 
               
               
                 Ib1.70 
                 O 
                 H 
                 C(CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ib1.71 
                 O 
                 H 
                 C(CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ib1.72 
                 O 
                 H 
                 C(CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ib1.73 
                 O 
                 H 
                 C(CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.74 
                 O 
                 H 
                 C(CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ib1.75 
                 O 
                 H 
                 C(CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ib1.76 
                 O 
                 CH 3   
                 C(CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ib1.77 
                 O 
                 CH 3   
                 C(CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.78 
                 O 
                 CH 3   
                 C(CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.79 
                 O 
                 CH 3   
                 C(CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.80 
                 O 
                 CH 3   
                 C(CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.81 
                 O 
                 CH 3   
                 C(CH 3 ) 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.82 
                 O 
                 CH 3   
                 C(CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ib1.83 
                 O 
                 CH 3   
                 C(CH 3 ) 
                 Br 
                 OH 
               
               
                 Ib1.84 
                 O 
                 CH 3   
                 C(CH 3 ) 
                 NO 2   
                 OH 
               
               
                 Ib1.85 
                 O 
                 CH 3   
                 C(CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ib1.86 
                 O 
                 CH 3   
                 C(CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ib1.87 
                 O 
                 CH 3   
                 C(CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ib1.88 
                 O 
                 CH 3   
                 C(CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.89 
                 O 
                 CH 3   
                 C(CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ib1.90 
                 O 
                 CH 3   
                 C(CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ib1.91 
                 O 
                 CH 2 CH 3   
                 C(CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ib1.92 
                 O 
                 CH 2 CH 3   
                 C(CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.93 
                 O 
                 CH 2 CH 3   
                 C(CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.94 
                 O 
                 CH 2 CH 3   
                 C(CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.95 
                 O 
                 CH 2 CH 3   
                 C(CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.96 
                 O 
                 CH 2 CH 3   
                 C(CH 3 ) 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.97 
                 O 
                 CH 2 CH 3   
                 C(CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ib1.98 
                 O 
                 CH 2 CH 3   
                 C(CH 3 ) 
                 Br 
                 OH 
               
               
                 Ib1.99 
                 O 
                 CH 2 CH 3   
                 C(CH 3 ) 
                 NO 2   
                 OH 
               
               
                 Ib1.100 
                 O 
                 CH 2 CH 3   
                 C(CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ib1.101 
                 O 
                 CH 2 CH 3   
                 C(CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ib1.102 
                 O 
                 CH 2 CH 3   
                 C(CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ib1.103 
                 O 
                 CH 2 CH 3   
                 C(CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.104 
                 O 
                 CH 2 CH 3   
                 C(CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ib1.105 
                 O 
                 CH 2 CH 3   
                 C(CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ib1.106 
                 O 
                 CH 2 Cl 
                 C(CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ib1.107 
                 O 
                 CH 2 Cl 
                 C(CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.108 
                 O 
                 CH 2 Cl 
                 C(CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.109 
                 O 
                 CH 2 Cl 
                 C(CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.110 
                 O 
                 CH 2 Cl 
                 C(CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.111 
                 O 
                 CH 2 Cl 
                 C(CH 3 ) 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.112 
                 O 
                 CH 2 Cl 
                 C(CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ib1.113 
                 O 
                 CH 2 Cl 
                 C(CH 3 ) 
                 Br 
                 OH 
               
               
                 Ib1.114 
                 O 
                 CH 2 Cl 
                 C(CH 3 ) 
                 NO 2   
                 OH 
               
               
                 Ib1.115 
                 O 
                 CH 2 Cl 
                 C(CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ib1.116 
                 O 
                 CH 2 Cl 
                 C(CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ib1.117 
                 O 
                 CH 2 Cl 
                 C(CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ib1.118 
                 O 
                 CH 2 Cl 
                 C(CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.119 
                 O 
                 CH 2 Cl 
                 C(CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ib1.120 
                 O 
                 CH 2 Cl 
                 C(CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ib1.121 
                 O 
                 H 
                 C(CH 2 CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ib1.122 
                 O 
                 H 
                 C(CH 2 CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.123 
                 O 
                 H 
                 C(CH 2 CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.124 
                 O 
                 H 
                 C(CH 2 CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.125 
                 O 
                 H 
                 C(CH 2 CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.126 
                 O 
                 H 
                 C(CH 2 CH 3 ) 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.127 
                 O 
                 H 
                 C(CH 2 CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ib1.128 
                 O 
                 H 
                 C(CH 2 CH 3 ) 
                 Br 
                 OH 
               
               
                 Ib1.129 
                 O 
                 H 
                 C(CH 2 CH 3 ) 
                 NO 2   
                 OH 
               
               
                 Ib1.130 
                 O 
                 H 
                 C(CH 2 CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ib1.131 
                 O 
                 H 
                 C(CH 2 CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ib1.132 
                 O 
                 H 
                 C(CH 2 CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ib1.133 
                 O 
                 H 
                 C(CH 2 CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.134 
                 O 
                 H 
                 C(CH 2 CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ib1.135 
                 O 
                 H 
                 C(CH 2 CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ib1.136 
                 O 
                 CH 3   
                 C(CH 2 CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ib1.137 
                 O 
                 CH 3   
                 C(CH 2 CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.138 
                 O 
                 CH 3   
                 C(CH 2 CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.139 
                 O 
                 CH 3   
                 C(CH 2 CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.140 
                 O 
                 CH 3   
                 C(CH 2 CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.141 
                 O 
                 CH 3   
                 C(CH 2 CH 3 ) 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.142 
                 O 
                 CH 3   
                 C(CH 2 CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ib1.143 
                 O 
                 CH 3   
                 C(CH 2 CH 3 ) 
                 Br 
                 OH 
               
               
                 Ib1.144 
                 O 
                 CH 3   
                 C(CH 2 CH 3 ) 
                 NO 2   
                 OH 
               
               
                 Ib1.145 
                 O 
                 CH 3   
                 C(CH 2 CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ib1.146 
                 O 
                 CH 3   
                 C(CH 2 CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ib1.147 
                 O 
                 CH 3   
                 C(CH 2 CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ib1.148 
                 O 
                 CH 3   
                 C(CH 2 CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.149 
                 O 
                 CH 3   
                 C(CH 2 CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ib1.150 
                 O 
                 CH 3   
                 C(CH 2 CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ib1.151 
                 O 
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ib1.152 
                 O 
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.153 
                 O 
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.154 
                 O 
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.155 
                 O 
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.156 
                 O 
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.157 
                 O 
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ib1.158 
                 O 
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 Br 
                 OH 
               
               
                 Ib1.159 
                 O 
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 NO 2   
                 OH 
               
               
                 Ib1.160 
                 O 
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ib1.161 
                 O 
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ib1.162 
                 O 
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ib1.163 
                 O 
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.164 
                 O 
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ib1.165 
                 O 
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ib1.166 
                 O 
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ib1.167 
                 O 
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.168 
                 O 
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.169 
                 O 
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.170 
                 O 
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.171 
                 O 
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.172 
                 O 
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ib1.173 
                 O 
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 Br 
                 OH 
               
               
                 Ib1.174 
                 O 
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 NO 3   
                 OH 
               
               
                 Ib1.175 
                 O 
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ib1.176 
                 O 
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ib1.177 
                 O 
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ib1.178 
                 O 
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.179 
                 O 
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ib1.180 
                 O 
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ib1.181 
                 NCH 3   
                 H 
                 CH 
                 SCH 3   
                 OH 
               
               
                 Ib1.182 
                 NCH 3   
                 H 
                 CH 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.183 
                 NCH 3   
                 H 
                 CH 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.184 
                 NCH 3   
                 H 
                 CH 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.185 
                 NCH 3   
                 H 
                 CH 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.186 
                 NCH 3   
                 H 
                 CH 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.187 
                 NCH 3   
                 H 
                 CH 
                 Cl 
                 OH 
               
               
                 Ib1.188 
                 NCH 3   
                 H 
                 CH 
                 Br 
                 OH 
               
               
                 Ib1.189 
                 NCH 3   
                 H 
                 CH 
                 NO 2   
                 OH 
               
               
                 Ib1.190 
                 NCH 3   
                 H 
                 CH 
                 CHF 2   
                 OH 
               
               
                 Ib1.191 
                 NCH 3   
                 H 
                 CH 
                 CF 3   
                 OH 
               
               
                 Ib1.192 
                 NCH 3   
                 H 
                 CH 
                 OCH 3   
                 OH 
               
               
                 Ib1.193 
                 NCH 3   
                 H 
                 CH 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.194 
                 NCH 3   
                 H 
                 CH 
                 OCHF 2   
                 OH 
               
               
                 Ib1.195 
                 NCH 3   
                 H 
                 CH 
                 OCF 3   
                 OH 
               
               
                 Ib1.196 
                 NCH 3   
                 CH 3   
                 CH 
                 SCH 3   
                 OH 
               
               
                 Ib1.197 
                 NCH 3   
                 CH 3   
                 CH 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.198 
                 NCH 3   
                 CH 3   
                 CH 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.199 
                 NCH 3   
                 CH 3   
                 CH 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.200 
                 NCH 3   
                 CH 3   
                 CH 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.201 
                 NCH 3   
                 CH 3   
                 CH 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.202 
                 NCH 3   
                 CH 3   
                 CH 
                 Cl 
                 OH 
               
               
                 Ib1.203 
                 NCH 3   
                 CH 3   
                 CH 
                 Br 
                 OH 
               
               
                 Ib1.204 
                 NCH 3   
                 CH 3   
                 CH 
                 NO 2   
                 OH 
               
               
                 Ib1.205 
                 NCH 3   
                 CH 3   
                 CH 
                 CHF 2   
                 OH 
               
               
                 Ib1.206 
                 NCH 3   
                 CH 3   
                 CH 
                 CF 3   
                 OH 
               
               
                 Ib1.207 
                 NCH 3   
                 CH 3   
                 CH 
                 OCH 3   
                 OH 
               
               
                 Ib1.208 
                 NCH 3   
                 CH 3   
                 CH 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.209 
                 NCH 3   
                 CH 3   
                 CH 
                 OCHF 2   
                 OH 
               
               
                 Ib1.210 
                 NCH 3   
                 CH 3   
                 CH 
                 OCF 3   
                 OH 
               
               
                 Ib1.211 
                 NCH 3   
                 CH 2 CH 3   
                 CH 
                 SCH 3   
                 OH 
               
               
                 Ib1.212 
                 NCH 3   
                 CH 2 CH 3   
                 CH 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.213 
                 NCH 3   
                 CH 2 CH 3   
                 CH 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.214 
                 NCH 3   
                 CH 2 CH 3   
                 CH 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.215 
                 NCH 3   
                 CH 2 CH 3   
                 CH 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.216 
                 NCH 3   
                 CH 2 CH 3   
                 CH 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.217 
                 NCH 3   
                 CH 2 CH 3   
                 CH 
                 Cl 
                 OH 
               
               
                 Ib1.218 
                 NCH 3   
                 CH 2 CH 3   
                 CH 
                 Br 
                 OH 
               
               
                 Ib1.219 
                 NCH 3   
                 CH 2 CH 3   
                 CH 
                 NO 2   
                 OH 
               
               
                 Ib1.220 
                 NCH 3   
                 CH 2 CH 3   
                 CH 
                 CHF 2   
                 OH 
               
               
                 Ib1.221 
                 NCH 3   
                 CH 2 CH 3   
                 CH 
                 CF 3   
                 OH 
               
               
                 Ib1.222 
                 NCH 3   
                 CH 2 CH 3   
                 CH 
                 OCH 3   
                 OH 
               
               
                 Ib1.223 
                 NCH 3   
                 CH 2 CH 3   
                 CH 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.224 
                 NCH 3   
                 CH 2 CH 3   
                 CH 
                 OCHF 2   
                 OH 
               
               
                 Ib1.225 
                 NCH 3   
                 CH 2 CH 3   
                 CH 
                 OCF 3   
                 OH 
               
               
                 Ib1.226 
                 NCH 3   
                 CH 2 Cl 
                 CH 
                 SCH 3   
                 OH 
               
               
                 Ib1.227 
                 NCH 3   
                 CH 2 Cl 
                 CH 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.228 
                 NCH 3   
                 CH 2 Cl 
                 CH 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.229 
                 NCH 3   
                 CH 2 Cl 
                 CH 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.230 
                 NCH 3   
                 CH 2 Cl 
                 CH 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.231 
                 NCH 3   
                 CH 2 Cl 
                 CH 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.232 
                 NCH 3   
                 CH 2 Cl 
                 CH 
                 Cl 
                 OH 
               
               
                 Ib1.233 
                 NCH 3   
                 CH 2 Cl 
                 CH 
                 Br 
                 OH 
               
               
                 Ib1.234 
                 NCH 3   
                 CH 2 Cl 
                 CH 
                 NO 2   
                 OH 
               
               
                 Ib1.235 
                 NCH 3   
                 CH 2 Cl 
                 CH 
                 CHF 2   
                 OH 
               
               
                 Ib1.236 
                 NCH 3   
                 CH 2 Cl 
                 CH 
                 CF 3   
                 OH 
               
               
                 Ib1.237 
                 NCH 3   
                 CH 2 Cl 
                 CH 
                 OCH 3   
                 OH 
               
               
                 Ib1.238 
                 NCH 3   
                 CH 2 Cl 
                 CH 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.239 
                 NCH 3   
                 CH 2 Cl 
                 CH 
                 OCHF 2   
                 OH 
               
               
                 Ib1.240 
                 NCH 3   
                 CH 2 Cl 
                 CH 
                 OCF 3   
                 OH 
               
               
                 Ib1.241 
                 NCH 3   
                 H 
                 C(CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ib1.242 
                 NCH 3   
                 H 
                 C(CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.243 
                 NCH 3   
                 H 
                 C(CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.244 
                 NCH 3   
                 H 
                 C(CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.245 
                 NCH 3   
                 H 
                 C(CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.246 
                 NCH 3   
                 H 
                 C(CH 3 ) 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.247 
                 NCH 3   
                 H 
                 C(CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ib1.248 
                 NCH 3   
                 H 
                 C(CH 3 ) 
                 Br 
                 OH 
               
               
                 Ib1.249 
                 NCH 3   
                 H 
                 C(CH 3 ) 
                 NO 2   
                 OH 
               
               
                 Ib1.250 
                 NCH 3   
                 H 
                 C(CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ib1.251 
                 NCH 3   
                 H 
                 C(CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ib1.252 
                 NCH 3   
                 H 
                 C(CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ib1.253 
                 NCH 3   
                 H 
                 C(CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.254 
                 NCH 3   
                 H 
                 C(CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ib1.255 
                 NCH 3   
                 H 
                 C(CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ib1.256 
                 NCH 3   
                 CH 3   
                 C(CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ib1.257 
                 NCH 3   
                 CH 3   
                 C(CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.258 
                 NCH 3   
                 CH 3   
                 C(CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.259 
                 NCH 3   
                 CH 3   
                 C(CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.260 
                 NCH 3   
                 CH 3   
                 C(CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.261 
                 NCH 3   
                 CH 3   
                 C(CH 3 ) 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.262 
                 NCH 3   
                 CH 3   
                 C(CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ib1.263 
                 NCH 3   
                 CH 3   
                 C(CH 3 ) 
                 Br 
                 OH 
               
               
                 Ib1.264 
                 NCH 3   
                 CH 3   
                 C(CH 3 ) 
                 NO 2   
                 OH 
               
               
                 Ib1.265 
                 NCH 3   
                 CH 3   
                 C(CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ib1.266 
                 NCH 3   
                 CH 3   
                 C(CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ib1.267 
                 NCH 3   
                 CH 3   
                 C(CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ib1.268 
                 NCH 3   
                 CH 3   
                 C(CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.269 
                 NCH 3   
                 CH 3   
                 C(CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ib1.270 
                 NCH 3   
                 CH 3   
                 C(CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ib1.271 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ib1.272 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.273 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.274 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.275 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.276 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 3 ) 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.277 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ib1.278 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 3 ) 
                 Br 
                 OH 
               
               
                 Ib1.279 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 3 ) 
                 NO 2   
                 OH 
               
               
                 Ib1.280 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ib1.281 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ib1.282 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ib1.283 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.284 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ib1.285 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ib1.286 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ib1.287 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.288 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.289 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.290 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.291 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 3 ) 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.292 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ib1.293 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 3 ) 
                 Br 
                 OH 
               
               
                 Ib1.294 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 3 ) 
                 NO 2   
                 OH 
               
               
                 Ib1.295 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ib1.296 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ib1.297 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ib1.298 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.299 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ib1.300 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ib1.301 
                 NCH 3   
                 H 
                 C(CH 2 CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ib1.302 
                 NCH 3   
                 H 
                 C(CH 2 CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.303 
                 NCH 3   
                 H 
                 C(CH 2 CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.304 
                 NCH 3   
                 H 
                 C(CH 2 CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.305 
                 NCH 3   
                 H 
                 C(CH 2 CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.306 
                 NCH 3   
                 H 
                 C(CH 2 CH 3 ) 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.307 
                 NCH 3   
                 H 
                 C(CH 2 CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ib1.308 
                 NCH 3   
                 H 
                 C(CH 2 CH 3 ) 
                 Br 
                 OH 
               
               
                 Ib1.309 
                 NCH 3   
                 H 
                 C(CH 2 CH 3 ) 
                 NO 2   
                 OH 
               
               
                 Ib1.310 
                 NCH 3   
                 H 
                 C(CH 2 CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ib1.311 
                 NCH 3   
                 H 
                 C(CH 2 CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ib1.312 
                 NCH 3   
                 H 
                 C(CH 2 CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ib1.313 
                 NCH 3   
                 H 
                 C(CH 2 CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.314 
                 NCH 3   
                 H 
                 C(CH 2 CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ib1.315 
                 NCH 3   
                 H 
                 C(CH 2 CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ib1.316 
                 NCH 3   
                 CH 3   
                 C(CH 2 CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ib1.317 
                 NCH 3   
                 CH 3   
                 C(CH 2 CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.318 
                 NCH 3   
                 CH 3   
                 C(CH 2 CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.319 
                 NCH 3   
                 CH 3   
                 C(CH 2 CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.320 
                 NCH 3   
                 CH 3   
                 C(CH 2 CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.321 
                 NCH 3   
                 CH 3   
                 C(CH 2 CH 3 ) 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.322 
                 NCH 3   
                 CH 3   
                 C(CH 2 CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ib1.323 
                 NCH 3   
                 CH 3   
                 C(CH 2 CH 3 ) 
                 Br 
                 OH 
               
               
                 Ib1.324 
                 NCH 3   
                 CH 3   
                 C(CH 2 CH 3 ) 
                 NO 2   
                 OH 
               
               
                 Ib1.325 
                 NCH 3   
                 CH 3   
                 C(CH 2 CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ib1.326 
                 NCH 3   
                 CH 3   
                 C(CH 2 CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ib1.327 
                 NCH 3   
                 CH 3   
                 C(CH 2 CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ib1.329 
                 NCH 3   
                 CH 3   
                 C(CH 2 CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.329 
                 NCH 3   
                 CH 3   
                 C(CH 2 CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ib1.330 
                 NCH 3   
                 CH 3   
                 C(CH 2 CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ib1.331 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ib1.332 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.333 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.334 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.335 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.336 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.337 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ib1.338 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 Br 
                 OH 
               
               
                 Ib1.339 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 NO 2   
                 OH 
               
               
                 Ib1.340 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ib1.341 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ib1.342 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ib1.343 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.344 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ib1.345 
                 NCH 3   
                 CH 2 CH 3   
                 C(CH 2 CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ib1.346 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 SCH 3   
                 OH 
               
               
                 Ib1.347 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.348 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.349 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.350 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.351 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.352 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 Cl 
                 OH 
               
               
                 Ib1.353 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 Br 
                 OH 
               
               
                 Ib1.354 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 NO 2   
                 OH 
               
               
                 Ib1.355 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 CHF 2   
                 OH 
               
               
                 Ib1.356 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 CF 3   
                 OH 
               
               
                 Ib1.357 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 OCH 3   
                 OH 
               
               
                 Ib1.358 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.359 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 OCHF 2   
                 OH 
               
               
                 Ib1.360 
                 NCH 3   
                 CH 2 Cl 
                 C(CH 2 CH 3 ) 
                 OCF 3   
                 OH 
               
               
                 Ib1.361 
                 NCH 3   
                 H 
                 N 
                 SCH 3   
                 OH 
               
               
                 Ib1.362 
                 NCH 3   
                 H 
                 N 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.363 
                 NCH 3   
                 H 
                 N 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.364 
                 NCH 3   
                 H 
                 N 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.365 
                 NCH 3   
                 H 
                 N 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.366 
                 NCH 3   
                 H 
                 N 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.367 
                 NCH 3   
                 H 
                 N 
                 Cl 
                 OH 
               
               
                 Ib1.368 
                 NCH 3   
                 H 
                 N 
                 Br 
                 OH 
               
               
                 Ib1.369 
                 NCH 3   
                 H 
                 N 
                 NO 2   
                 OH 
               
               
                 Ib1.370 
                 NCH 3   
                 H 
                 N 
                 CHF 2   
                 OH 
               
               
                 Ib1.371 
                 NCH 3   
                 H 
                 N 
                 CF 3   
                 OH 
               
               
                 Ib1.372 
                 NCH 3   
                 H 
                 N 
                 OCH 3   
                 OH 
               
               
                 Ib1.373 
                 NCH 3   
                 H 
                 N 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.374 
                 NCH 3   
                 H 
                 N 
                 OCHF 2   
                 OH 
               
               
                 Ib1.375 
                 NCH 3   
                 H 
                 N 
                 OCF 3   
                 OH 
               
               
                 Ib1.376 
                 NCH 3   
                 CH 3   
                 N 
                 SCH 3   
                 OH 
               
               
                 Ib1.377 
                 NCH 3   
                 CH 3   
                 N 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.378 
                 NCH 3   
                 CH 3   
                 N 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.379 
                 NCH 3   
                 CH 3   
                 N 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.380 
                 NCH 3   
                 CH 3   
                 N 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.381 
                 NCH 3   
                 CH 3   
                 N 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.382 
                 NCH 3   
                 CH 3   
                 N 
                 Cl 
                 OH 
               
               
                 Ib1.383 
                 NCH 3   
                 CH 3   
                 N 
                 Br 
                 OH 
               
               
                 Ib1.384 
                 NCH 3   
                 CH 3   
                 N 
                 NO 2   
                 OH 
               
               
                 Ib1.385 
                 NCH 3   
                 CH 3   
                 N 
                 CHF 2   
                 OH 
               
               
                 Ib1.386 
                 NCH 3   
                 CH 3   
                 N 
                 CF 3   
                 OH 
               
               
                 Ib1.387 
                 NCH 3   
                 CH 3   
                 N 
                 OCH 3   
                 OH 
               
               
                 Ib1.388 
                 NCH 3   
                 CH 3   
                 N 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.389 
                 NCH 3   
                 CH 3   
                 N 
                 OCHF 2   
                 OH 
               
               
                 Ib1.390 
                 NCH 3   
                 CH 3   
                 N 
                 OCF 3   
                 OH 
               
               
                 Ib1.391 
                 NCH 3   
                 CH 2 CH 3   
                 N 
                 SCH 3   
                 OH 
               
               
                 Ib1.392 
                 NCH 3   
                 CH 2 CH 3   
                 N 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.393 
                 NCH 3   
                 CH 2 CH 3   
                 N 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.394 
                 NCH 3   
                 CH 2 CH 3   
                 N 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.395 
                 NCH 3   
                 CH 2 CH 3   
                 N 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.396 
                 NCH 3   
                 CH 2 CH 3   
                 N 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.397 
                 NCH 3   
                 CH 2 CH 3   
                 N 
                 Cl 
                 OH 
               
               
                 Ib1.398 
                 NCH 3   
                 CH 2 CH 3   
                 N 
                 Br 
                 OH 
               
               
                 Ib1.399 
                 NCH 3   
                 CH 2 CH 3   
                 N 
                 NO 3   
                 OH 
               
               
                 Ib1.400 
                 NCH 3   
                 CH 2 CH 3   
                 N 
                 CHF 2   
                 OH 
               
               
                 Ib1.401 
                 NCH 3   
                 CH 2 CH 3   
                 N 
                 CF 3   
                 OH 
               
               
                 Ib1.402 
                 NCH 3   
                 CH 2 CH 3   
                 N 
                 OCH 3   
                 OH 
               
               
                 Ib1.403 
                 NCH 3   
                 CH 2 CH 3   
                 N 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.404 
                 NCH 3   
                 CH 2 CH 3   
                 N 
                 OCHF 2   
                 OH 
               
               
                 Ib1.405 
                 NCH 3   
                 CH 2 CH 3   
                 N 
                 OCF 3   
                 OH 
               
               
                 Ib1.406 
                 NCH 3   
                 CH 2 Cl 
                 N 
                 SCH 3   
                 OH 
               
               
                 Ib1.407 
                 NCH 3   
                 CH 2 Cl 
                 N 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ib1.408 
                 NCH 3   
                 CH 2 Cl 
                 N 
                 SO 2 CH 3   
                 OH 
               
               
                 Ib1.409 
                 NCH 3   
                 CH 2 Cl 
                 N 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ib1.410 
                 NCH 3   
                 CH 2 Cl 
                 N 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ib1.411 
                 NCH 3   
                 CH 2 Cl 
                 N 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ib1.412 
                 NCH 3   
                 CH 2 Cl 
                 N 
                 Cl 
                 OH 
               
               
                 Ib1.413 
                 NCH 3   
                 CH 2 Cl 
                 N 
                 Br 
                 OH 
               
               
                 Ib1.414 
                 NCH 3   
                 CH 2 Cl 
                 N 
                 NO 2   
                 OH 
               
               
                 Ib1.415 
                 NCH 3   
                 CH 2 Cl 
                 N 
                 CHF 2   
                 OH 
               
               
                 Ib1.416 
                 NCH 3   
                 CH 2 Cl 
                 N 
                 CF 3   
                 OH 
               
               
                 Ib1.417 
                 NCH 3   
                 CH 2 Cl 
                 N 
                 OCH 3   
                 OH 
               
               
                 Ib1.418 
                 NCH 3   
                 CH 2 Cl 
                 N 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ib1.419 
                 NCH 3   
                 CH 2 Cl 
                 N 
                 OCHF 2   
                 OH 
               
               
                 Ib1.420 
                 NCH 3   
                 CH 2 Cl 
                 N 
                 OCF 3   
                 OH 
               
               
                   
               
            
           
         
       
     
     Most particular preference is also given to the compounds of the formula Ib2, in particular to the compounds Ib2.1 to Ib2.420 which differ from the corresponding compounds Ib1.1 to Ib1.420 in that R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ib3, in particular to the compounds Ib3.1 to Ib3.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 13  is cyclopentyl.                    
     Most particular preference is also given to the compounds of the formula Ib4, in particular to the compounds Ib4.1 to Ib4.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 13  is cyclopentyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ib5, in particular to the compounds Ib5.1 to Ib5.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 13  is cyclohexyl.                    
     Most particular preference is also given to the compounds of the formula Ib6, in particular to the compounds Ib6.1 to Ib6.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 13  is cyclohexyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ib7, in particular to the compounds Ib7.1 to Ib7.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 13  is 2-norbornyl.                    
     Most particular preference is also given to the compounds of the formula Ib8, in particular to the compounds Ib8.1 to Ib8.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 13  is 2-norbornyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ib9, in particular to the compounds Ib9.1 to Ib9.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 13  is 2-adamantyl.                    
     Most particular preference is also given to the compounds of the formula Ib10, in particular to the compounds Ib10.1 to Ib10.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 13  is 2-adamantyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ib11, in particular to the compounds Ib11.1 to Ib11.420 which differ from the corresponding compounds Ib1.1 to Ib1.420 in that R 1  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ib12, in particular to the compounds Ib12.1 to Ib12.420 which differ from the corresponding compounds Ib1.1 to Ib1.420 in that R 1  is methyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ib13, in particular to the compounds Ib13.1 to Ib13.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 1  is methyl and R 13  is cyclopentyl.                    
     Most particular preference is also given to the compounds of the formula Ib14, in particular to the compounds Ib14.1 to Ib14.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 1  is methyl, R 13  is cyclopentyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ib15, in particular to the compounds Ib15.1 to Ib15.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 1  is methyl and R 13  is cyclohexyl.                    
     Most particular preference is also given to the compounds of the formula Ib16, in particular to the compounds Ib16.1 to Ib16.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 1  is methyl, R 13  is cyclohexyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ib17, in particular to the compounds Ib17.1 to Ib17.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 1  is methyl and R 13  is 2-norbornyl.                    
     Most particular preference is also given to the compounds of the formula Ib18, in particular to the compounds Ib18.1 to Ib18.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 1  is methyl, R 13  is 2-norbornyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ib19, in particular to the compounds Ib19.1 to Ib19.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 1  is methyl and R 13  is 2-adamantyl.                    
     Most particular preference is also given to the compounds of the formula Ib20, in particular to the compounds Ib20.1 to Ib20.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 1  is methyl, R 13  is 2-adamantyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ib21, in particular to the compounds Ib21.1 to Ib21.420 which differ from the corresponding compounds Ib1.1 to Ib1.420 in that R 1  is methoxy.                    
     Most particular preference is also given to the compounds of the formula Ib22, in particular to the compounds Ib22.1 to Ib22.420 which differ from the corresponding compounds Ib1.1 to Ib1.420 in that R 1  is methoxy and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ib23, in particular to the compounds Ib23.1 to Ib23.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 1  is methoxy and R 13  is cyclopentyl.                    
     Most particular preference is also given to the compounds of the formula Ib24, in particular to the compounds Ib24.1 to Ib24.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 1  is methoxy, R 13  is cyclopentyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ib25, in particular to the compounds Ib25.1 to Ib25.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 1  is methoxy and R 13  is cyclohexyl.                    
     Most particular preference is also given to the compounds of the formula Ib26, in particular to the compounds Ib26.1 to Ib26.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 1  is methoxy, R 13  is cyclohexyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ib27, in particular to the compounds Ib27.1 to Ib27.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 1  is methoxy and R 13  is 2-norbornyl.                    
     Most particular preference is also given to the compounds of the formula Ib28, in particular to the compounds Ib28.1 to Ib28.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 1  is methoxy, R 13  is 2-norbornyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ib29, in particular to the compounds Ib29.1 to Ib29.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 1  is methoxy and R 13  is 2-adamantyl.                    
     Most particular preference is also given to the compounds of the formula Ib30, in particular to the compounds Ib30.1 to Ib30.420 which differ from the compounds Ib1.1 to Ib1.420 in that R 1  is methoxy, R 13  is 2-adamantyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ic1 (=I where R 1 =Cl, R 3  and R 6  or R 3  and R 8  together form a bond, R 13 =cyclo-C 3 H 5  and R 5  and R 14 =H), in particular to the compounds Ic1.1-Ic1.720 of Table 3, where the radical definitions are of particular importance for the compounds according to the invention not only in combination with one another but in each case also on their own.                    
     
       
         
           
               
               
               
               
               
               
             
               
                 TABLE 3 
               
               
                   
               
               
                 No. 
                 X 
                 R 2   
                 Y 
                 R 4   
                 R 8   
               
               
                   
               
             
            
               
                 Ic1.1 
                 CH 
                 H 
                 O 
                 SCH 3   
                 OH 
               
               
                 Ic1.2 
                 CH 
                 H 
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.3 
                 CH 
                 H 
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.4 
                 CH 
                 H 
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.5 
                 CH 
                 H 
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.6 
                 CH 
                 H 
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.7 
                 CH 
                 H 
                 O 
                 Cl 
                 OH 
               
               
                 Ic1.8 
                 CH 
                 H 
                 O 
                 Br 
                 OH 
               
               
                 Ic1.9 
                 CH 
                 H 
                 O 
                 NO 2   
                 OH 
               
               
                 Ic1.10 
                 CH 
                 H 
                 O 
                 CHF 2   
                 OH 
               
               
                 Ic1.11 
                 CH 
                 H 
                 O 
                 CF 3   
                 OH 
               
               
                 Ic1.12 
                 CH 
                 H 
                 O 
                 OCH 3   
                 OH 
               
               
                 Ic1.13 
                 CH 
                 H 
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.14 
                 CH 
                 H 
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ic1.15 
                 CH 
                 H 
                 O 
                 OCF 3   
                 OH 
               
               
                 Ic1.16 
                 CH 
                 CH 3   
                 O 
                 SCH 3   
                 OH 
               
               
                 Ic1.17 
                 CH 
                 CH 3   
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.18 
                 CH 
                 CH 3   
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.19 
                 CH 
                 CH 3   
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.20 
                 CH 
                 CH 3   
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.21 
                 CH 
                 CH 3   
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.22 
                 CH 
                 CH 3   
                 O 
                 Cl 
                 OH 
               
               
                 Ic1.23 
                 CH 
                 CH 3   
                 O 
                 Br 
                 OH 
               
               
                 Ic1.24 
                 CH 
                 CH 3   
                 O 
                 NO 2   
                 OH 
               
               
                 Ic1.25 
                 CH 
                 CH 3   
                 O 
                 CHF 2   
                 OH 
               
               
                 Ic1.26 
                 CH 
                 CH 3   
                 O 
                 CF 3   
                 OH 
               
               
                 Ic1.27 
                 CH 
                 CH 3   
                 O 
                 OCH 3   
                 OH 
               
               
                 Ic1.28 
                 CH 
                 CH 3   
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.29 
                 CH 
                 CH 3   
                 O 
                 OCF 2   
                 OH 
               
               
                 Ic1.30 
                 CH 
                 CH 3   
                 O 
                 OCF 3   
                 OM 
               
               
                 Ic1.31 
                 CH 
                 CH 2 CH 3   
                 O 
                 SCH 3   
                 OH 
               
               
                 Ic1.32 
                 CH 
                 CH 2 CH 3   
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.33 
                 CH 
                 CH 2 CH 3   
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.34 
                 CH 
                 CH 2 CH 3   
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.35 
                 CH 
                 CH 2 CH 3   
                 O 
                 SO 2 CH(CH 3 ) 3   
                 OH 
               
               
                 Ic1.36 
                 CH 
                 CH 2 CH 3   
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.37 
                 CH 
                 CH 2 CH 3   
                 O 
                 Cl 
                 OH 
               
               
                 Ic1.38 
                 CH 
                 CH 2 CH 3   
                 O 
                 Br 
                 OH 
               
               
                 Ic1.39 
                 CH 
                 CH 2 CH 3   
                 O 
                 NO 2   
                 OH 
               
               
                 Ic1.40 
                 CH 
                 CH 2 CH 3   
                 O 
                 CHF 2   
                 OH 
               
               
                 Ic1.41 
                 CH 
                 CH 2 CH 3   
                 O 
                 CF 3   
                 OH 
               
               
                 Ic1.42 
                 CH 
                 CH 2 CH 3   
                 O 
                 OCH 3   
                 OH 
               
               
                 Ic1.43 
                 CH 
                 CH 2 CH 3   
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.44 
                 CH 
                 CH 2 CH 3   
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ic1.45 
                 CH 
                 CH 2 CH 3   
                 O 
                 OCF 3   
                 OH 
               
               
                 Ic1.46 
                 CH 
                 CH 2 Cl 
                 O 
                 SCH 3   
                 OH 
               
               
                 Ic1.47 
                 CH 
                 CH 2 Cl 
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.48 
                 CH 
                 CH 2 Cl 
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.49 
                 CH 
                 CH 2 Cl 
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.50 
                 CH 
                 CH 2 Cl 
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.51 
                 CH 
                 CH 2 Cl 
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.52 
                 CH 
                 CH 2 Cl 
                 O 
                 Cl 
                 OH 
               
               
                 Ic1.53 
                 CH 
                 CH 2 Cl 
                 O 
                 Br 
                 OH 
               
               
                 Ic1.54 
                 CH 
                 CH 2 Cl 
                 O 
                 NO 2   
                 OH 
               
               
                 Ic1.55 
                 CH 
                 CH 2 Cl 
                 O 
                 CHF 2   
                 OH 
               
               
                 Ic1.56 
                 CH 
                 CH 2 Cl 
                 O 
                 CF 3   
                 OH 
               
               
                 Ic1.57 
                 CH 
                 CH 2 Cl 
                 O 
                 OCH 3   
                 OH 
               
               
                 Ic1.58 
                 CH 
                 CH 2 Cl 
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.59 
                 CH 
                 CH 2 Cl 
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ic1.60 
                 CH 
                 CH 2 Cl 
                 O 
                 OCF 3   
                 OH 
               
               
                 Ic1.61 
                 CH 
                 H 
                 S 
                 SCH 3   
                 OH 
               
               
                 Ic1.62 
                 CH 
                 H 
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.63 
                 CH 
                 H 
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.64 
                 CH 
                 H 
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.65 
                 CH 
                 H 
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.66 
                 CH 
                 H 
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.67 
                 CH 
                 H 
                 S 
                 Cl 
                 OH 
               
               
                 Ic1.68 
                 CH 
                 H 
                 S 
                 Br 
                 OH 
               
               
                 Ic1.69 
                 CH 
                 H 
                 S 
                 NO 2   
                 OH 
               
               
                 Ic1.70 
                 CH 
                 H 
                 S 
                 CHF 2   
                 OH 
               
               
                 Ic1.71 
                 CH 
                 H 
                 S 
                 CF 3   
                 OH 
               
               
                 Ic1.72 
                 CH 
                 H 
                 S 
                 OCH 3   
                 OH 
               
               
                 Ic1.73 
                 CH 
                 H 
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.74 
                 CH 
                 H 
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ic1.75 
                 CH 
                 H 
                 S 
                 OCF 3   
                 OH 
               
               
                 Ic1.76 
                 CH 
                 CH 3   
                 S 
                 SCH 3   
                 OH 
               
               
                 Ic1.77 
                 CH 
                 CH 3   
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.78 
                 CH 
                 CH 3   
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.79 
                 CH 
                 CH 3   
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.80 
                 CH 
                 CH 3   
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.81 
                 CH 
                 CH 3   
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.82 
                 CH 
                 CH 3   
                 S 
                 Cl 
                 OH 
               
               
                 Ic1.83 
                 CH 
                 CH 3   
                 S 
                 Br 
                 OH 
               
               
                 Ic1.84 
                 CH 
                 CH 3   
                 S 
                 NO 2   
                 OH 
               
               
                 Ic1.85 
                 CH 
                 CH 3   
                 S 
                 CHF 2   
                 OH 
               
               
                 Ic1.86 
                 CH 
                 CH 3   
                 S 
                 CF 3   
                 OH 
               
               
                 Ic1.87 
                 CH 
                 CH 3   
                 S 
                 OCH 3   
                 OH 
               
               
                 Ic1.88 
                 CH 
                 CH 3   
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.89 
                 CH 
                 CH 3   
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ic1.90 
                 CH 
                 CH 3   
                 S 
                 OCF 3   
                 OH 
               
               
                 Ic1.91 
                 CH 
                 CH 2 CH 3   
                 S 
                 SCH 3   
                 OH 
               
               
                 Ic1.92 
                 CH 
                 CH 2 CH 3   
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.93 
                 CH 
                 CH 2 CH 3   
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.94 
                 CH 
                 CH 2 CH 3   
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.95 
                 CH 
                 CH 2 CH 3   
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.96 
                 CH 
                 CH 2 CH 3   
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.97 
                 CH 
                 CH 2 CH 3   
                 S 
                 Cl 
                 OH 
               
               
                 Ic1.98 
                 CH 
                 CH 2 CH 3   
                 S 
                 Br 
                 OH 
               
               
                 Ic1.99 
                 CH 
                 CH 2 CH 3   
                 S 
                 NO 2   
                 OH 
               
               
                 Ic1.100 
                 CH 
                 CH 2 CH 3   
                 S 
                 CHF 2   
                 OH 
               
               
                 Ic1.101 
                 CH 
                 CH 2 CH 3   
                 S 
                 CF 3   
                 OH 
               
               
                 Ic1.102 
                 CH 
                 CH 2 CH 3   
                 S 
                 OCH 3   
                 OH 
               
               
                 Ic1.103 
                 CH 
                 CH 2 CH 3   
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.104 
                 CH 
                 CH 2 CH 3   
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ic1.105 
                 CH 
                 CH 2 CH 3   
                 S 
                 OCF 3   
                 OH 
               
               
                 Ic1.106 
                 CH 
                 CH 2 Cl 
                 S 
                 SCH 3   
                 OH 
               
               
                 Ic1.107 
                 CH 
                 CH 2 Cl 
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.108 
                 CH 
                 CH 2 Cl 
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.109 
                 CH 
                 CH 2 Cl 
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.110 
                 CH 
                 CH 2 Cl 
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.111 
                 CH 
                 CH 2 Cl 
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.112 
                 CH 
                 CH 2 Cl 
                 S 
                 Cl 
                 OH 
               
               
                 Ic1.113 
                 CH 
                 CH 2 Cl 
                 S 
                 Br 
                 OH 
               
               
                 Ic1.114 
                 CH 
                 CH 2 Cl 
                 S 
                 NO 2   
                 OH 
               
               
                 Ic1.115 
                 CH 
                 CH 2 Cl 
                 S 
                 CHF 2   
                 OH 
               
               
                 Ic1.116 
                 CH 
                 CH 2 Cl 
                 S 
                 CF 3   
                 OH 
               
               
                 Ic1.117 
                 CH 
                 CH 2 Cl 
                 S 
                 OCH 3   
                 OH 
               
               
                 Ic1.118 
                 CH 
                 CH 2 Cl 
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.119 
                 CH 
                 CH 2 Cl 
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ic1.120 
                 CH 
                 CH 2 Cl 
                 S 
                 OCF 3   
                 OH 
               
               
                 Ic1.121 
                 CH 
                 H 
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ic1.122 
                 CH 
                 H 
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.123 
                 CH 
                 H 
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.124 
                 CH 
                 H 
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.125 
                 CH 
                 H 
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.126 
                 CH 
                 H 
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.127 
                 CH 
                 H 
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ic1.128 
                 CH 
                 H 
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ic1.129 
                 CH 
                 H 
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ic1.130 
                 CH 
                 H 
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ic1.131 
                 CH 
                 H 
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ic1.132 
                 CH 
                 H 
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ic1.133 
                 CH 
                 H 
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.134 
                 CH 
                 H 
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ic1.135 
                 CH 
                 H 
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ic1.136 
                 CH 
                 CH 3   
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ic1.137 
                 CH 
                 CH 3   
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.138 
                 CH 
                 CH 3   
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.139 
                 CH 
                 CH 3   
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.140 
                 CH 
                 CH 3   
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.141 
                 CH 
                 CH 3   
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.142 
                 CH 
                 CH 3   
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ic1.143 
                 CH 
                 CH 3   
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ic1.144 
                 CH 
                 CH 3   
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ic1.145 
                 CH 
                 CH 3   
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ic1.146 
                 CH 
                 CH 3   
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ic1.147 
                 CH 
                 CH 3   
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ic1.148 
                 CH 
                 CH 3   
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.149 
                 CH 
                 CH 3   
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ic1.150 
                 CH 
                 CH 3   
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ic1.151 
                 CH 
                 CH 2 CH 3   
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ic1.152 
                 CH 
                 CH 2 CH 3   
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.153 
                 CH 
                 CH 2 CH 3   
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.154 
                 CH 
                 CH 2 CH 3   
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.155 
                 CH 
                 CH 2 CH 3   
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.156 
                 CH 
                 CH 2 CH 3   
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.157 
                 CH 
                 CH 2 CH 3   
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ic1.158 
                 CH 
                 CH 2 CH 3   
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ic1.159 
                 CH 
                 CH 2 CH 3   
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ic1.160 
                 CH 
                 CH 2 CH 3   
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ic1.161 
                 CH 
                 CH 2 CH 3   
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ic1.162 
                 CH 
                 CH 2 CH 3   
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ic1.163 
                 CH 
                 CH 2 CH 3   
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.164 
                 CH 
                 CH 2 CH 3   
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ic1.165 
                 CH 
                 CH 2 CH 3   
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ic1.166 
                 CH 
                 CH 2 Cl 
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ic1.167 
                 CH 
                 CH 2 Cl 
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.168 
                 CH 
                 CH 2 Cl 
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.169 
                 CH 
                 CH 2 Cl 
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.170 
                 CH 
                 CH 2 Cl 
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.171 
                 CH 
                 CH 2 Cl 
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.172 
                 CH 
                 CH 2 Cl 
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ic1.173 
                 CH 
                 CH 2 Cl 
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ic1.174 
                 CH 
                 CH 2 Cl 
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ic1.175 
                 CH 
                 CH 2 Cl 
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ic1.176 
                 CH 
                 CH 2 Cl 
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ic1.177 
                 CH 
                 CH 2 Cl 
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ic1.178 
                 CH 
                 CH 2 Cl 
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.179 
                 CH 
                 CH 2 Cl 
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ic1.180 
                 CH 
                 CH 2 Cl 
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ic1.181 
                 C(CH 3 ) 
                 H 
                 O 
                 SCH 3   
                 OH 
               
               
                 Ic1.182 
                 C(CH 3 ) 
                 H 
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.183 
                 C(CH 3 ) 
                 H 
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.184 
                 C(CH 3 ) 
                 H 
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.185 
                 C(CH 3 ) 
                 H 
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.186 
                 C(CH 3 ) 
                 H 
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.187 
                 C(CH 3 ) 
                 H 
                 O 
                 Cl 
                 OH 
               
               
                 Ic1.188 
                 C(CH 3 ) 
                 H 
                 O 
                 Br 
                 OH 
               
               
                 Ic1.189 
                 C(CH 3 ) 
                 H 
                 O 
                 NO 2   
                 OH 
               
               
                 Ic1.190 
                 C(CH 3 ) 
                 H 
                 O 
                 CHF 2   
                 OH 
               
               
                 Ic1.191 
                 C(CH 3 ) 
                 H 
                 O 
                 CF 3   
                 OH 
               
               
                 Ic1.192 
                 C(CH 3 ) 
                 H 
                 O 
                 OCH 3   
                 OH 
               
               
                 Ic1.193 
                 C(CH 3 ) 
                 H 
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.194 
                 C(CH 3 ) 
                 H 
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ic1.195 
                 C(CH 3 ) 
                 H 
                 O 
                 OCF 3   
                 OH 
               
               
                 Ic1.196 
                 C(CH 3 ) 
                 CH 3   
                 O 
                 SCH 3   
                 OH 
               
               
                 Ic1.197 
                 C(CH 3 ) 
                 CH 3   
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.198 
                 C(CH 3 ) 
                 CH 3   
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.199 
                 C(CH 3 ) 
                 CH 3   
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.200 
                 C(CH 3 ) 
                 CH 3   
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.201 
                 C(CH 3 ) 
                 CH 3   
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.202 
                 C(CH 3 ) 
                 CH 3   
                 O 
                 Cl 
                 OH 
               
               
                 Ic1.203 
                 C(CH 3 ) 
                 CH 3   
                 O 
                 Br 
                 OH 
               
               
                 Ic1.204 
                 C(CH 3 ) 
                 CH 3   
                 O 
                 NO 2   
                 OH 
               
               
                 Ic1.205 
                 C(CH 3 ) 
                 CH 3   
                 O 
                 CHF 2   
                 OH 
               
               
                 Ic1.206 
                 C(CH 3 ) 
                 CH 3   
                 O 
                 CF 3   
                 OH 
               
               
                 Ic1.207 
                 C(CH 3 ) 
                 CH 3   
                 O 
                 OCH 3   
                 OH 
               
               
                 Ic1.208 
                 C(CH 3 ) 
                 CH 3   
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.209 
                 C(CH 3 ) 
                 CH 3   
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ic1.210 
                 C(CH 3 ) 
                 CH 3   
                 O 
                 OCF 3   
                 OH 
               
               
                 Ic1.211 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 O 
                 SCH 3   
                 OH 
               
               
                 Ic1.212 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.213 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.214 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.215 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.216 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.217 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 O 
                 Cl 
                 OH 
               
               
                 Ic1.218 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 O 
                 Br 
                 OH 
               
               
                 Ic1.219 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 O 
                 NO 2   
                 OH 
               
               
                 Ic1.220 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 O 
                 CHF 2   
                 OH 
               
               
                 Ic1.221 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 O 
                 CF 3   
                 OH 
               
               
                 Ic1.222 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 O 
                 OCH 3   
                 OH 
               
               
                 Ic1.223 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.224 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ic1.225 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 O 
                 OCF 3   
                 OH 
               
               
                 Ic1.226 
                 C(CH 3 ) 
                 CH 2 Cl 
                 O 
                 SCH 3   
                 OH 
               
               
                 Ic1.227 
                 C(CH 3 ) 
                 CH 2 Cl 
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.228 
                 C(CH 3 ) 
                 CH 2 Cl 
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.229 
                 C(CH 3 ) 
                 CH 2 Cl 
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.230 
                 C(CH 3 ) 
                 CH 2 Cl 
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.231 
                 C(CH 3 ) 
                 CH 2 Cl 
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.232 
                 C(CH 3 ) 
                 CH 2 Cl 
                 O 
                 Cl 
                 OH 
               
               
                 Ic1.233 
                 C(CH 3 ) 
                 CH 2 Cl 
                 O 
                 Br 
                 OH 
               
               
                 Ic1.234 
                 C(CH 3 ) 
                 CH 2 Cl 
                 O 
                 NO 2   
                 OH 
               
               
                 Ic1.235 
                 C(CH 3 ) 
                 CH 2 Cl 
                 O 
                 CHF 2   
                 OH 
               
               
                 Ic1.236 
                 C(CH 3 ) 
                 CH 2 Cl 
                 O 
                 CF 3   
                 OH 
               
               
                 Ic1.237 
                 C(CH 3 ) 
                 CH 2 Cl 
                 O 
                 OCH 3   
                 OH 
               
               
                 Ic1.238 
                 C(CH 3 ) 
                 CH 2 Cl 
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.239 
                 C(CH 3 ) 
                 CH 2 Cl 
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ic1.240 
                 C(CH 3 ) 
                 CH 2 Cl 
                 O 
                 OCF 3   
                 OH 
               
               
                 Ic1.241 
                 C(CH 3 ) 
                 H 
                 S 
                 SCH 3   
                 OH 
               
               
                 Ic1.242 
                 C(CH 3 ) 
                 H 
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.243 
                 C(CH 3 ) 
                 H 
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.244 
                 C(CH 3 ) 
                 H 
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.245 
                 C(CH 3 ) 
                 H 
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.246 
                 C(CH 3 ) 
                 H 
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.247 
                 C(CH 3 ) 
                 H 
                 S 
                 Cl 
                 OH 
               
               
                 Ic1.248 
                 C(CH 3 ) 
                 H 
                 S 
                 Br 
                 OH 
               
               
                 Ic1.249 
                 C(CH 3 ) 
                 H 
                 S 
                 NO 2   
                 OH 
               
               
                 Ic1.250 
                 C(CH 3 ) 
                 H 
                 S 
                 CHF 2   
                 OH 
               
               
                 Ic1.251 
                 C(CH 3 ) 
                 H 
                 S 
                 CF 3   
                 OH 
               
               
                 Ic1.252 
                 C(CH 3 ) 
                 H 
                 S 
                 OCH 3   
                 OH 
               
               
                 Ic1.253 
                 C(CH 3 ) 
                 H 
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.254 
                 C(CH 3 ) 
                 H 
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ic1.255 
                 C(CH 3 ) 
                 H 
                 S 
                 OCF 3   
                 OH 
               
               
                 Ic1.256 
                 C(CH 3 ) 
                 CH 3   
                 S 
                 SCH 3   
                 OH 
               
               
                 Ic1.257 
                 C(CH 3 ) 
                 CH 3   
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.258 
                 C(CH 3 ) 
                 CH 3   
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.259 
                 C(CH 3 ) 
                 CH 3   
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.260 
                 C(CH 3 ) 
                 CH 3   
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.261 
                 C(CH 3 ) 
                 CH 3   
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.262 
                 C(CH 3 ) 
                 CH 3   
                 S 
                 Cl 
                 OH 
               
               
                 Ic1.263 
                 C(CH 3 ) 
                 CH 3   
                 S 
                 Br 
                 OH 
               
               
                 Ic1.264 
                 C(CH 3 ) 
                 CH 3   
                 S 
                 NO 2   
                 OH 
               
               
                 Ic1.265 
                 C(CH 3 ) 
                 CH 3   
                 S 
                 CHF 3   
                 OH 
               
               
                 Ic1.266 
                 C(CH 3 ) 
                 CH 3   
                 S 
                 CF 3   
                 OH 
               
               
                 Ic1.267 
                 C(CH 3 ) 
                 CH 3   
                 S 
                 OCH 3   
                 OH 
               
               
                 Ic1.268 
                 C(CH 3 ) 
                 CH 3   
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.269 
                 C(CH 3 ) 
                 CH 3   
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ic1.270 
                 C(CH 3 ) 
                 CH 3   
                 S 
                 OCF 3   
                 OH 
               
               
                 Ic1.271 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 S 
                 SCH 3   
                 OH 
               
               
                 Ic1.272 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.273 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.274 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.275 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.276 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.277 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 S 
                 Cl 
                 OH 
               
               
                 Ic1.278 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 S 
                 Br 
                 OH 
               
               
                 Ic1.279 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 S 
                 NO 2   
                 OH 
               
               
                 Ic1.280 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 S 
                 CHF 2   
                 OH 
               
               
                 Ic1.281 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 S 
                 CF 3   
                 OH 
               
               
                 Ic1.282 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 S 
                 OCH 3   
                 OH 
               
               
                 Ic1.283 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.284 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ic1.285 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 S 
                 OCF 3   
                 OH 
               
               
                 Ic1.286 
                 C(CH 3 ) 
                 CH 2 Cl 
                 S 
                 SCH 3   
                 OH 
               
               
                 Ic1.287 
                 C(CH 3 ) 
                 CH 2 Cl 
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.288 
                 C(CH 3 ) 
                 CH 2 Cl 
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.289 
                 C(CH 3 ) 
                 CH 2 Cl 
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.290 
                 C(CH 3 ) 
                 CH 2 Cl 
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.291 
                 C(CH 3 ) 
                 CH 2 Cl 
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.292 
                 C(CH 3 ) 
                 CH 2 Cl 
                 S 
                 Cl 
                 OH 
               
               
                 Ic1.293 
                 C(CH 3 ) 
                 CH 2 Cl 
                 S 
                 Br 
                 OH 
               
               
                 Ic1.294 
                 C(CH 3 ) 
                 CH 2 Cl 
                 S 
                 NO 2   
                 OH 
               
               
                 Ic1.295 
                 C(CH 3 ) 
                 CH 2 Cl 
                 S 
                 CHF 2   
                 OH 
               
               
                 Ic1.296 
                 C(CH 3 ) 
                 CH 2 Cl 
                 S 
                 CF 3   
                 OH 
               
               
                 Ic1.297 
                 C(CH 3 ) 
                 CH 2 Cl 
                 S 
                 OCH 3   
                 OH 
               
               
                 Ic1.298 
                 C(CH 3 ) 
                 CH 2 Cl 
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.299 
                 C(CH 3 ) 
                 CH 2 Cl 
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ic1.300 
                 C(CH 3 ) 
                 CH 2 Cl 
                 S 
                 OCF 3   
                 OH 
               
               
                 Ic1.301 
                 C(CH 3 ) 
                 H 
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ic1.302 
                 C(CH 3 ) 
                 H 
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.303 
                 C(CH 3 ) 
                 H 
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.304 
                 C(CH 3 ) 
                 H 
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.305 
                 C(CH 3 ) 
                 H 
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.306 
                 C(CH 3 ) 
                 H 
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.307 
                 C(CH 3 ) 
                 H 
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ic1.308 
                 C(CH 3 ) 
                 H 
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ic1.309 
                 C(CH 3 ) 
                 H 
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ic1.310 
                 C(CH 3 ) 
                 H 
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ic1.311 
                 C(CH 3 ) 
                 H 
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ic1.312 
                 C(CH 3 ) 
                 H 
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ic1.313 
                 C(CH 3 ) 
                 H 
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.314 
                 C(CH 3 ) 
                 H 
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ic1.315 
                 C(CH 3 ) 
                 H 
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ic1.316 
                 C(CH 3 ) 
                 CH 3   
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ic1.317 
                 C(CH 3 ) 
                 CH 3   
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.318 
                 C(CH 3 ) 
                 CH 3   
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.319 
                 C(CH 3 ) 
                 CH 3   
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.320 
                 C(CH 3 ) 
                 CH 3   
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.321 
                 C(CH 3 ) 
                 CH 3   
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.322 
                 C(CH 3 ) 
                 CH 3   
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ic1.323 
                 C(CH 3 ) 
                 CH 3   
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ic1.324 
                 C(CH 3 ) 
                 CH 3   
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ic1.325 
                 C(CH 3 ) 
                 CH 3   
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ic1.326 
                 C(CH 3 ) 
                 CH 3   
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ic1.327 
                 C(CH 3 ) 
                 CH 3   
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ic1.328 
                 C(CH 3 ) 
                 CH 3   
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.329 
                 C(CH 3 ) 
                 CH 3   
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ic1.330 
                 C(CH 3 ) 
                 CH 3   
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ic1.331 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ic1.332 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.333 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 SO 2 CH 2   
                 OH 
               
               
                 Ic1.334 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.335 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 SO 2 CH(CH 2 ) 2   
                 OH 
               
               
                 Ic1.336 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.337 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ic1.338 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ic1.339 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ic1.340 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ic1.341 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ic1.342 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ic1.343 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.344 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ic1.345 
                 C(CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ic1.346 
                 C(CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ic1.347 
                 C(CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.348 
                 C(CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.349 
                 C(CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.350 
                 C(CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.351 
                 C(CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.352 
                 C(CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ic1.353 
                 C(CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ic1.354 
                 C(CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ic1.355 
                 C(CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ic1.356 
                 C(CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ic1.357 
                 C(CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ic1.358 
                 C(CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.359 
                 C(CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ic1.360 
                 C(CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ic1.361 
                 C(CH 2 CH 3 ) 
                 H 
                 O 
                 SCH 3   
                 OH 
               
               
                 Ic1.362 
                 C(CH 2 CH 3 ) 
                 H 
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.363 
                 C(CH 2 CH 3 ) 
                 H 
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.364 
                 C(CH 2 CH 3 ) 
                 H 
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.365 
                 C(CH 2 CH 3 ) 
                 H 
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.366 
                 C(CH 2 CH 3 ) 
                 H 
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.367 
                 C(CH 2 CH 3 ) 
                 H 
                 O 
                 Cl 
                 OH 
               
               
                 Ic1.368 
                 C(CH 2 CH 3 ) 
                 H 
                 O 
                 Br 
                 OH 
               
               
                 Ic1.369 
                 C(CH 2 CH 3 ) 
                 H 
                 O 
                 NO 2   
                 OH 
               
               
                 Ic1.370 
                 C(CH 2 CH 3 ) 
                 H 
                 O 
                 CHF 2   
                 OH 
               
               
                 Ic1.371 
                 C(CH 2 CH 3 ) 
                 H 
                 O 
                 CF 3   
                 OH 
               
               
                 Ic1.372 
                 C(CH 2 CH 3 ) 
                 H 
                 O 
                 OCH 3   
                 OH 
               
               
                 Ic1.373 
                 C(CH 2 CH 3 ) 
                 H 
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.374 
                 C(CH 2 CH 3 ) 
                 H 
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ic1.375 
                 C(CH 2 CH 3 ) 
                 H 
                 O 
                 OCF 3   
                 OH 
               
               
                 Ic1.376 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 O 
                 SCH 3   
                 OH 
               
               
                 Ic1.377 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.378 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.379 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.380 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.381 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.382 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 O 
                 Cl 
                 OH 
               
               
                 Ic1.383 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 O 
                 Br 
                 OH 
               
               
                 Ic1.384 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 O 
                 NO 2   
                 OH 
               
               
                 Ic1.385 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 O 
                 CHF 2   
                 OH 
               
               
                 Ic1.386 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 O 
                 CF 3   
                 OH 
               
               
                 Ic1.387 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 O 
                 OCH 3   
                 OH 
               
               
                 Ic1.388 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.389 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ic1.390 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 O 
                 OCF 3   
                 OH 
               
               
                 Ic1.391 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 O 
                 SCH 3   
                 OH 
               
               
                 Ic1.392 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.393 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.394 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.395 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.396 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.397 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 O 
                 Cl 
                 OH 
               
               
                 Ic1.398 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 O 
                 Br 
                 OH 
               
               
                 Ic1.399 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 O 
                 NO 2   
                 OH 
               
               
                 Ic1.400 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 O 
                 CHF 2   
                 OH 
               
               
                 Ic1.401 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 O 
                 CF 3   
                 OH 
               
               
                 Ic1.402 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 O 
                 OCH 3   
                 OH 
               
               
                 Ic1.403 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.404 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ic1.405 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 O 
                 OCF 3   
                 OH 
               
               
                 Ic1.406 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 O 
                 SCH 3   
                 OH 
               
               
                 Ic1.407 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.408 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.409 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.410 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.411 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.412 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 O 
                 Cl 
                 OH 
               
               
                 Ic1.413 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 O 
                 Br 
                 OH 
               
               
                 Ic1.414 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 O 
                 NO 2   
                 OH 
               
               
                 Ic1.415 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 O 
                 CHF 2   
                 OH 
               
               
                 Ic1.416 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 O 
                 CF 3   
                 OH 
               
               
                 Ic1.417 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 O 
                 OCH 3   
                 OH 
               
               
                 Ic1.418 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.419 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ic1.420 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 O 
                 OCF 3   
                 OH 
               
               
                 Ic1.421 
                 C(CH 2 CH 3 ) 
                 H 
                 S 
                 SCH 3   
                 OH 
               
               
                 Ic1.422 
                 C(CH 2 CH 3 ) 
                 H 
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.423 
                 C(CH 2 CH 3 ) 
                 H 
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.424 
                 C(CH 2 CH 3 ) 
                 H 
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.425 
                 C(CH 2 CH 3 ) 
                 H 
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.426 
                 C(CH 2 CH 3 ) 
                 H 
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.427 
                 C(CH 2 CH 3 ) 
                 H 
                 S 
                 Cl 
                 OH 
               
               
                 Ic1.428 
                 C(CH 2 CH 3 ) 
                 H 
                 S 
                 Br 
                 OH 
               
               
                 Ic1.429 
                 C(CH 2 CH 3 ) 
                 H 
                 S 
                 NO 2   
                 OH 
               
               
                 Ic1.430 
                 C(CH 2 CH 3 ) 
                 H 
                 S 
                 CHF 2   
                 OH 
               
               
                 Ic1.431 
                 C(CH 2 CH 3 ) 
                 H 
                 S 
                 CF 3   
                 OH 
               
               
                 Ic1.432 
                 C(CH 2 CH 3 ) 
                 H 
                 S 
                 OCH 3   
                 OH 
               
               
                 Ic1.433 
                 C(CH 2 CH 3 ) 
                 H 
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.434 
                 C(CH 2 CH 3 ) 
                 H 
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ic1.435 
                 C(CH 2 CH 3 ) 
                 H 
                 S 
                 OCF 3   
                 OH 
               
               
                 Ic1.436 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 S 
                 SCH 3   
                 OH 
               
               
                 Ic1.437 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.438 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.439 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.440 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.441 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.442 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 S 
                 Cl 
                 OH 
               
               
                 Ic1.443 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 S 
                 Br 
                 OH 
               
               
                 Ic1.444 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 S 
                 NO 2   
                 OH 
               
               
                 Ic1.445 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 S 
                 CHF 2   
                 OH 
               
               
                 Ic1.446 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 S 
                 CF 3   
                 OH 
               
               
                 Ic1.447 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 S 
                 OCH 3   
                 OH 
               
               
                 Ic1.448 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.449 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ic1.450 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 S 
                 OCF 3   
                 OH 
               
               
                 Ic1.451 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 S 
                 SCH 3   
                 OH 
               
               
                 Ic1.452 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.453 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.454 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.455 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.456 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.457 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 S 
                 Cl 
                 OH 
               
               
                 Ic1.458 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 S 
                 Br 
                 OH 
               
               
                 Ic1.459 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 S 
                 NO 2   
                 OH 
               
               
                 Ic1.460 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 S 
                 CHF 2   
                 OH 
               
               
                 Ic1.461 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 S 
                 CF 3   
                 OH 
               
               
                 Ic1.462 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 S 
                 OCH 3   
                 OH 
               
               
                 Ic1.463 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.464 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ic1.465 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 S 
                 OCF 3   
                 OH 
               
               
                 Ic1.466 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 S 
                 SCH 3   
                 OH 
               
               
                 Ic1.467 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.468 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.469 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.470 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.471 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.472 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 S 
                 Cl 
                 OH 
               
               
                 Ic1.473 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 S 
                 Br 
                 OH 
               
               
                 Ic1.474 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 S 
                 NO 2   
                 OH 
               
               
                 Ic1.475 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 S 
                 CHF 2   
                 OH 
               
               
                 Ic1.476 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 S 
                 CF 3   
                 OH 
               
               
                 Ic1.477 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 S 
                 OCH 3   
                 OH 
               
               
                 Ic1.478 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.479 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ic1.480 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 S 
                 OCF 3   
                 OH 
               
               
                 Ic1.481 
                 C(CH 2 CH 3 ) 
                 H 
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ic1.482 
                 C(CH 2 CH 3 ) 
                 H 
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.483 
                 C(CH 2 CH 3 ) 
                 H 
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.484 
                 C(CH 2 CH 3 ) 
                 H 
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.485 
                 C(CH 2 CH 3 ) 
                 H 
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.486 
                 C(CH 2 CH 3 ) 
                 H 
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.487 
                 C(CH 2 CH 3 ) 
                 H 
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ic1.488 
                 C(CH 2 CH 3 ) 
                 H 
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ic1.489 
                 C(CH 2 CH 3 ) 
                 H 
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ic1.490 
                 C(CH 2 CH 3 ) 
                 H 
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ic1.491 
                 C(CH 2 CH 3 ) 
                 H 
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ic1.492 
                 C(CH 2 CH 3 ) 
                 H 
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ic1.493 
                 C(CH 2 CH 3 ) 
                 H 
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.494 
                 C(CH 2 CH 3 ) 
                 H 
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ic1.495 
                 C(CH 2 CH 3 ) 
                 H 
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ic1.496 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ic1.497 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.498 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.499 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.500 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.501 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.502 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ic1.503 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ic1.504 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ic1.505 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ic1.506 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ic1.507 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ic1.508 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.509 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ic1.510 
                 C(CH 2 CH 3 ) 
                 CH 3   
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ic1.511 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ic1.512 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.513 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.514 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.515 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.516 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.517 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ic1.518 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ic1.519 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ic1.520 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ic1.521 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ic1.522 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ic1.523 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.524 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ic1.525 
                 C(CH 2 CH 3 ) 
                 CH 2 CH 3   
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ic1.526 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ic1.527 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.528 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.529 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.530 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.531 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.532 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ic1.533 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ic1.534 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ic1.535 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ic1.536 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ic1.537 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ic1.538 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.539 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ic1.540 
                 C(CH 2 CH 3 ) 
                 CH 2 Cl 
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ic1.541 
                 N 
                 H 
                 O 
                 SCH 3   
                 OH 
               
               
                 Ic1.542 
                 N 
                 H 
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.543 
                 N 
                 H 
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.544 
                 N 
                 H 
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.545 
                 N 
                 H 
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.546 
                 N 
                 H 
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.547 
                 N 
                 H 
                 O 
                 Cl 
                 OH 
               
               
                 Ic1.548 
                 N 
                 H 
                 O 
                 Br 
                 OH 
               
               
                 Ic1.549 
                 N 
                 H 
                 O 
                 NO 2   
                 OH 
               
               
                 Ic1.550 
                 N 
                 H 
                 O 
                 CHF 2   
                 OH 
               
               
                 Ic1.551 
                 N 
                 H 
                 O 
                 CF 3   
                 OH 
               
               
                 Ic1.552 
                 N 
                 H 
                 O 
                 OCH 3   
                 OH 
               
               
                 Ic1.553 
                 N 
                 H 
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.554 
                 N 
                 H 
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ic1.555 
                 N 
                 H 
                 O 
                 OCF 3   
                 OH 
               
               
                 Ic1.556 
                 N 
                 CH 3   
                 O 
                 SCH 3   
                 OH 
               
               
                 Ic1.557 
                 N 
                 CH 3   
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.558 
                 N 
                 CH 3   
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.559 
                 N 
                 CH 3   
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.560 
                 N 
                 CH 3   
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.561 
                 N 
                 CH 3   
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.562 
                 N 
                 CH 3   
                 O 
                 Cl 
                 OH 
               
               
                 Ic1.563 
                 N 
                 CH 3   
                 O 
                 Br 
                 OH 
               
               
                 Ic1.564 
                 N 
                 CH 3   
                 O 
                 NO 2   
                 OH 
               
               
                 Ic1.565 
                 N 
                 CH 3   
                 O 
                 CHF 2   
                 OH 
               
               
                 Ic1.566 
                 H 
                 CH 3   
                 O 
                 CF 3   
                 OH 
               
               
                 Ic1.567 
                 N 
                 CH 3   
                 O 
                 OCH 3   
                 OH 
               
               
                 Ic1.568 
                 N 
                 CH 3   
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.569 
                 N 
                 CH 3   
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ic1.570 
                 N 
                 CH 3   
                 O 
                 OCF 3   
                 OH 
               
               
                 Ic1.571 
                 N 
                 CH 2 CH 3   
                 O 
                 SCH 3   
                 OH 
               
               
                 Ic1.572 
                 N 
                 CH 2 CH 3   
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.573 
                 N 
                 CH 2 CH 3   
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.574 
                 N 
                 CH 2 CH 3   
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.575 
                 N 
                 CH 2 CH 3   
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.576 
                 N 
                 CH 2 CH 3   
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.577 
                 N 
                 CH 2 CH 3   
                 O 
                 Cl 
                 OH 
               
               
                 Ic1.578 
                 N 
                 CH 2 CH 3   
                 O 
                 Br 
                 OH 
               
               
                 Ic1.579 
                 N 
                 CH 2 CH 3   
                 O 
                 NO 2   
                 OH 
               
               
                 Ic1.580 
                 N 
                 CH 2 CH 3   
                 O 
                 CHF 2   
                 OH 
               
               
                 Ic1.581 
                 N 
                 CH 2 CH 3   
                 O 
                 CF 3   
                 OH 
               
               
                 Ic1.582 
                 N 
                 CH 2 CH 3   
                 O 
                 OCH 3   
                 OH 
               
               
                 Ic1.583 
                 N 
                 CH 2 CH 3   
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.584 
                 N 
                 CH 2 CH 3   
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ic1.585 
                 N 
                 CH 2 CH 3   
                 O 
                 OCF 3   
                 OH 
               
               
                 Ic1.586 
                 N 
                 CH 2 Cl 
                 O 
                 SCH 3   
                 OH 
               
               
                 Ic1.587 
                 N 
                 CH 2 Cl 
                 O 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.588 
                 N 
                 CH 2 Cl 
                 O 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.589 
                 N 
                 CH 2 Cl 
                 O 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.590 
                 N 
                 CH 2 Cl 
                 O 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.591 
                 N 
                 CH 2 Cl 
                 O 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.592 
                 N 
                 CH 2 Cl 
                 O 
                 Cl 
                 OH 
               
               
                 Ic1.593 
                 N 
                 CH 2 Cl 
                 O 
                 Br 
                 OH 
               
               
                 Ic1.594 
                 N 
                 CH 2 Cl 
                 O 
                 NO 2   
                 OH 
               
               
                 Ic1.595 
                 N 
                 CH 2 Cl 
                 O 
                 CHF 2   
                 OH 
               
               
                 Ic1.596 
                 N 
                 CH 2 Cl 
                 O 
                 CF 3   
                 OH 
               
               
                 Ic1.597 
                 N 
                 CH 2 Cl 
                 O 
                 OCH 3   
                 OH 
               
               
                 Ic1.598 
                 N 
                 CH 2 Cl 
                 O 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.599 
                 N 
                 CH 2 Cl 
                 O 
                 OCHF 2   
                 OH 
               
               
                 Ic1.600 
                 N 
                 CH 2 Cl 
                 O 
                 OCF 3   
                 OH 
               
               
                 Ic1.601 
                 N 
                 H 
                 S 
                 SCH 3   
                 OH 
               
               
                 Ic1.602 
                 N 
                 H 
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.603 
                 N 
                 H 
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.604 
                 N 
                 H 
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.605 
                 N 
                 H 
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.606 
                 N 
                 H 
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.607 
                 N 
                 H 
                 S 
                 Cl 
                 OH 
               
               
                 Ic1.608 
                 N 
                 H 
                 S 
                 Br 
                 OH 
               
               
                 Ic1.609 
                 N 
                 H 
                 S 
                 NO 2   
                 OH 
               
               
                 Ic1.610 
                 N 
                 H 
                 S 
                 CHF 2   
                 OH 
               
               
                 Ic1.611 
                 N 
                 H 
                 S 
                 CF 3   
                 OH 
               
               
                 Ic1.612 
                 N 
                 H 
                 S 
                 OCH 3   
                 OH 
               
               
                 Ic1.613 
                 N 
                 H 
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.614 
                 N 
                 H 
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ic1.615 
                 N 
                 H 
                 S 
                 OCF 3   
                 OH 
               
               
                 Ic1.616 
                 N 
                 CH 3   
                 S 
                 SCH 3   
                 OH 
               
               
                 Ic1.617 
                 N 
                 CH 3   
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.618 
                 N 
                 CH 3   
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.619 
                 N 
                 CH 3   
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.620 
                 N 
                 CH 3   
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.621 
                 N 
                 CH 3   
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.622 
                 N 
                 CH 3   
                 S 
                 Cl 
                 OH 
               
               
                 Ic1.623 
                 N 
                 CH 3   
                 S 
                 Br 
                 OH 
               
               
                 Ic1.624 
                 N 
                 CH 3   
                 S 
                 NO 2   
                 OH 
               
               
                 Ic1.625 
                 N 
                 CH 3   
                 S 
                 CHF 2   
                 OH 
               
               
                 Ic1.626 
                 N 
                 CH 3   
                 S 
                 CF 3   
                 OH 
               
               
                 Ic1.627 
                 N 
                 CH 3   
                 S 
                 OCH 3   
                 OH 
               
               
                 Ic1.628 
                 N 
                 CH 3   
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.629 
                 N 
                 CH 3   
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ic1.630 
                 N 
                 CH 3   
                 S 
                 OCF 3   
                 OH 
               
               
                 Ic1.631 
                 N 
                 CH 2 CH 3   
                 S 
                 SCH 3   
                 OH 
               
               
                 Ic1.632 
                 N 
                 CH 2 CH 3   
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.633 
                 N 
                 CH 2 CH 3   
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.634 
                 N 
                 CH 2 CH 3   
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.635 
                 N 
                 CH 2 CH 3   
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.636 
                 N 
                 CH 2 CH 3   
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.637 
                 N 
                 CH 2 CH 3   
                 S 
                 Cl 
                 OH 
               
               
                 Ic1.638 
                 N 
                 CH 2 CH 3   
                 S 
                 Br 
                 OH 
               
               
                 Ic1.639 
                 N 
                 CH 2 CH 3   
                 S 
                 NO 2   
                 OH 
               
               
                 Ic1.640 
                 N 
                 CH 2 CH 3   
                 S 
                 CHF 2   
                 OH 
               
               
                 Ic1.641 
                 N 
                 CH 2 CH 3   
                 S 
                 CF 3   
                 OH 
               
               
                 Ic1.642 
                 N 
                 CH 2 CH 3   
                 S 
                 OCH 3   
                 OH 
               
               
                 Ic1.643 
                 N 
                 CH 2 CH 3   
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.644 
                 N 
                 CH 2 CH 3   
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ic1.645 
                 N 
                 CH 2 CH 3   
                 S 
                 OCF 3   
                 OH 
               
               
                 Ic1.646 
                 N 
                 CH 2 Cl 
                 S 
                 SCH 3   
                 OH 
               
               
                 Ic1.647 
                 N 
                 CH 2 Cl 
                 S 
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.648 
                 N 
                 CH 2 Cl 
                 S 
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.649 
                 N 
                 CH 2 Cl 
                 S 
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.650 
                 N 
                 CH 2 Cl 
                 S 
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.651 
                 N 
                 CH 2 Cl 
                 S 
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.652 
                 N 
                 CH 2 Cl 
                 S 
                 Cl 
                 OH 
               
               
                 Ic1.653 
                 N 
                 CH 2 Cl 
                 S 
                 Br 
                 OH 
               
               
                 Ic1.654 
                 N 
                 CH 2 Cl 
                 S 
                 NO 2   
                 OH 
               
               
                 Ic1.655 
                 N 
                 CH 2 Cl 
                 S 
                 CHF 2   
                 OH 
               
               
                 Ic1.656 
                 H 
                 CH 2 Cl 
                 S 
                 CF 3   
                 OH 
               
               
                 Ic1.657 
                 N 
                 CH 2 Cl 
                 S 
                 OCH 3   
                 OH 
               
               
                 Ic1.658 
                 N 
                 CH 2 Cl 
                 S 
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.659 
                 N 
                 CH 2 Cl 
                 S 
                 OCHF 2   
                 OH 
               
               
                 Ic1.660 
                 N 
                 CH 2 Cl 
                 S 
                 OCF 3   
                 OH 
               
               
                 Ic1.661 
                 N 
                 H 
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ic1.662 
                 N 
                 H 
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.663 
                 N 
                 H 
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.664 
                 N 
                 H 
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.665 
                 N 
                 H 
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.666 
                 N 
                 H 
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.667 
                 N 
                 H 
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ic1.668 
                 N 
                 H 
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ic1.669 
                 N 
                 H 
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ic1.670 
                 N 
                 H 
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ic1.671 
                 N 
                 H 
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ic1.672 
                 N 
                 H 
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ic1.673 
                 N 
                 H 
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.674 
                 N 
                 H 
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ic1.675 
                 N 
                 H 
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ic1.676 
                 N 
                 CH 3   
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ic1.677 
                 N 
                 CH 3   
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.678 
                 N 
                 CH 3   
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.679 
                 N 
                 CH 3   
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.680 
                 N 
                 CH 3   
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.681 
                 N 
                 CH 3   
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.682 
                 N 
                 CH 3   
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ic1.683 
                 N 
                 CH 3   
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ic1.684 
                 N 
                 CH 3   
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ic1.685 
                 N 
                 CH 3   
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ic1.686 
                 N 
                 CH 3   
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ic1.687 
                 N 
                 CH 3   
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ic1.688 
                 N 
                 CH 3   
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.689 
                 N 
                 CH 3   
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ic1.690 
                 N 
                 CH 3   
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ic1.691 
                 N 
                 CH 2 CH 3   
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ic1.692 
                 N 
                 CH 2 CH 3   
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.693 
                 N 
                 CH 2 CH 3   
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.694 
                 N 
                 CH 2 CH 3   
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.695 
                 N 
                 CH 2 CH 3   
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.696 
                 N 
                 CH 2 CH 3   
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.697 
                 N 
                 CH 2 CH 3   
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ic1.698 
                 N 
                 CH 2 CH 3   
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ic1.699 
                 N 
                 CH 2 CH 3   
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ic1.700 
                 N 
                 CH 2 CH 3   
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ic1.701 
                 N 
                 CH 2 CH 3   
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ic1.702 
                 N 
                 CH 2 CH 3   
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ic1.703 
                 N 
                 CH 2 CH 3   
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.704 
                 N 
                 CH 2 CH 3   
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ic1.705 
                 N 
                 CH 2 CH 3   
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                 Ic1.706 
                 N 
                 CH 2 Cl 
                 NCH 3   
                 SCH 3   
                 OH 
               
               
                 Ic1.707 
                 N 
                 CH 2 Cl 
                 NCH 3   
                 SCH 2 CH 3   
                 OH 
               
               
                 Ic1.708 
                 N 
                 CH 2 Cl 
                 NCH 3   
                 SO 2 CH 3   
                 OH 
               
               
                 Ic1.709 
                 N 
                 CH 2 Cl 
                 NCH 3   
                 SO 2 CH 2 CH 3   
                 OH 
               
               
                 Ic1.710 
                 N 
                 CH 2 Cl 
                 NCH 3   
                 SO 2 CH(CH 3 ) 2   
                 OH 
               
               
                 Ic1.711 
                 N 
                 CH 2 Cl 
                 NCH 3   
                 SO 2 (CH 2 ) 2 CH 3   
                 OH 
               
               
                 Ic1.712 
                 N 
                 CH 2 Cl 
                 NCH 3   
                 Cl 
                 OH 
               
               
                 Ic1.713 
                 N 
                 CH 2 Cl 
                 NCH 3   
                 Br 
                 OH 
               
               
                 Ic1.714 
                 N 
                 CH 2 Cl 
                 NCH 3   
                 NO 2   
                 OH 
               
               
                 Ic1.715 
                 N 
                 CH 2 Cl 
                 NCH 3   
                 CHF 2   
                 OH 
               
               
                 Ic1.716 
                 N 
                 CH 2 Cl 
                 NCH 3   
                 CF 3   
                 OH 
               
               
                 Ic1.717 
                 N 
                 CH 2 Cl 
                 NCH 3   
                 OCH 3   
                 OH 
               
               
                 Ic1.718 
                 N 
                 CH 2 Cl 
                 NCH 3   
                 OCH 2 CH 3   
                 OH 
               
               
                 Ic1.719 
                 N 
                 CH 2 Cl 
                 NCH 3   
                 OCHF 2   
                 OH 
               
               
                 Ic1.720 
                 N 
                 CH 2 Cl 
                 NCH 3   
                 OCF 3   
                 OH 
               
               
                   
               
            
           
         
       
     
     Most particular preference is also given to the compounds of the formula Ic2, in particular to the compounds Ic2.1 to Ic2.720 which differ from the corresponding compounds Ic1.1 to Ic1.720 in that R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ic3, in particular to the compounds Ic3.1 to Ic3.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 13  is cyclopentyl.                    
     Most particular preference is also given to the compounds of the formula Ic4, in particular to the compounds Ic4.1 to Ic4.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 13  is cyclopentyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ic5, in particular to the compounds Ic5.1 to Ic5.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 13  is cyclohexyl.                    
     Most particular preference is also given to the compounds of the formula Ic6, in particular to the compounds Ic6.1 to Ic6.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 13  is cyclohexyl and R 14  is Methyl.                    
     Most particular preference is also given to the compounds of the formula Ic7, in particular to the compounds Ic7.1 to Ic7.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 13  is 2-norbornyl.                    
     Most particular preference is also given to the compounds of the formula Ic8, in particular to the compounds Ic8.1 to Ic8.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 13  is 2-norbornyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ic9, in particular to the compounds Ic9.1 to Ic9.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 13  is 2-adamantyl.                    
     Most particular preference is also given to the compounds of the formula Ic10, in particular to the compounds Ic10.1 to Ic10.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 13  is 2-adamantyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ic11, in particular to the compounds Ic11.1 to Ic11.720 which differ from the corresponding compounds Ic1.1 to Ic1.720 in that R 1  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ic12, in particular to the compounds Ic12.1 to Ic12.720 which differ from the corresponding compounds Ic1.1 to Ic1.720 in that R 1  is methyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ic13, in particular to the compounds Ic13.1 to Ic13.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 1  is methyl and R 13  is cyclopentyl.                    
     Most particular preference is also given to the compounds of the formula Ic14, in particular to the compounds Ic14.1 to Ic14.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 1  is methyl, R 13  is cyclopentyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ic15, in particular to the compounds Ic15.1 to Ic15.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 1  is methyl and R 13  is cyclohexyl.                    
     Most particular preference is also given to the compounds of the formula Ic16, in particular to the compounds Ic16.1 to Ic16.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 1  is methyl, R 13  is cyclohexyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ic17, in particular to the compounds Ic17.1 to Ic17.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 1  is methyl and R 13  is 2-norbornyl.                    
     Most particular preference is also given to the compounds of the formula Ic18, in particular to the compounds Ic18.1 to Ic18.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 1  is methyl, R 13  is 2-norbornyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ic19, in particular to the compounds Ic19.1 to Ic19.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 1  is methyl and R 13  is 2-adamantyl.                    
     Most particular preference is also given to the compounds of the formula Ic20, in particular to the compounds Ic20.1 to Ic20.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 1  is methyl, R 13  is 2-adamantyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ic21, in particular to the compounds Ic21.1 to Ic21.720 which differ from the corresponding compounds Ic1.1 to Ic1.720 in that R 1  is methoxy.                    
     Most particular preference is also given to the compounds of the formula Ic22, in particular to the compounds Ic22.1 to Ic22.720 which differ from the corresponding compounds Ic1.1 to Ic1.720 in that R 1  is methoxy and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ic23, in particular to the compounds Ic23.1 to Ic23.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 1  is methoxy and R 13  is cyclopentyl.                    
     Most particular preferenceis also given to the compounds of the formula Ic24, in particular to the compounds Ic24.1 to Ic24.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 1  is methoxy, R 13  is cyclopentyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ic25, in particular to the compounds Ic25.1 to Ic25.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 1  is methoxy and R 13  is cyclohexyl.                    
     Most particular preference is also given to the compounds of the formula Ic26, in particular to the compounds Ic26.1 to Ic26.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 1  is methoxy, R 13  is cyclohexyl and R 14  is methyl.                    
     Most particular preference is also given to the compounds of the formula Ic27, in particular to the compounds Ic27.1 to Ic27.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 1  is methoxy and R 13  is 2-norbornyl.                    
     Most particular preference is also given to the compounds of the formula Ic28, in particular to the compounds Ic28.1 to Ic28.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 1  is methoxy, R 13  is 2-norbornyl and R 14  is methyl.                    
     Most particular preference is Also given to the compounds of the formula Ic29, in particular to the compounds Ic29.1 to Ic29.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 1  is methoxy and R 13  is 2-adamantyl.                    
     Most particular preference is also given to the compounds of the formula Ic30, in particular to the compounds Ic30.1 to Ic30.720 which differ from the compounds Ic1.1 to Ic1.720 in that R 1  is methoxy, R 13  is 2-adamantyl and R 14  is methyl.                    
     The 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I can be obtained by various routes, for example by the processes below. 
     Process A 
     Reaction of pyrazoles of the formula II with an activated benzoic acid IIIα or a benzoic acid IIIβ, which is preferably activated in situ, to give the corresponding acylation product IV, followed by rearrangement, gives compounds of the formula I where R 12 =OH.                    
     L 1  is a nucleophilically displaceable leaving group, such as halogen, for example bromine, chlorine, hetaryl, for example imidazolyl, pyridyl, carboxylate, for example acetate, trifluoroacetate, etc. 
     The activated benzoic acid can be employed directly, such as in the case of the benzoyl halides, or be generated in situ, for example using dicyclohexylcarbodiimide, triphenylphosphine/azodicarboxylic ester, 2-pyridine disulfide/triphenylphosphine, carbonyldiimidazole, etc. 
     It may be advantageous to carry out the acylation reaction in the presence of a base. The reactants and the auxiliary base are advantageously employed in this case in equimolar amounts. A slight excess of auxiliary base, for example from 1.2 to 1.5 molar equivalents, based on II, may be advantageous in certain cases. 
     Suitable auxiliary bases are tertiary alkylamines, pyridine or alkali metal carbonates. Suitable for use as solvents are, for example, chlorinated hydrocarbons, such as methylene chloride, 1,2-dichloroethane, aromatic hydrocarbons, such as toluene, xylene, chlorobenzene, ethers, such as diethyl ether, methyl tert-butyl ether, dimethoxyethane, tetrahydrofuran, dioxane, polar aprotic solvents, such as acetonitrile, dimethylformamide, dimethyl sulfoxide, or esters, such as ethyl acetate, or mixtures of these. 
     If the activated carboxylic acid component used is a benzoyl halide, it may be advantageous to cool the reaction mixture to 0-10° C. when adding this reaction partner. The mixture is subsequently stirred at 20-100° C., preferably at 25-50° C., until the reaction has ended. work-up is carried out in a customary manner, for example by pouring the reaction mixture into water and extracting the product of value. Solvents which are particularly suitable for this purpose are methylene chloride, diethyl ether, dimethoxyethane and ethyl acetate. The organic phase is dried and the solvent is removed, after which the crude ester can be employed for the rearrangement without any further purification. 
     The rearrangement of the esters to the compounds of the formula I is advantageously carried out at 20-40° C. in a solvent and in the presence of a base and, if appropriate, using a cyano compound as catalyst. 
     Suitable solvents are, for example, acetonitrile, methylene chloride, 1,2-dichlorcethane, dioxane, ethyl acetate, dimethoxyethane, toluene or mixtures of these. Preferred solvents are acetonitrile and dioxane. 
     Suitable bases are tertiary amines, such as triethylamine or pyridine, or alkali metal carbonates, such as sodium carbonate or potassium carbonate, which are preferably employed in an equimolar amount or an up to four-fold excess, based on the ester. Preference is given to using triethylamine or alkali metal carbonates, preferably in twice the equimolar amount, based on the ester. 
     Suitable cyano compounds are inorganic cyanides, such as sodium cyanide and potassium cyanide, and organic cyano compounds, such as acetone cyanohydrin and trimethylsilyl cyanide. They are employed in an amount of from 1 to 50 mol percent, based on the ester. Preference is given to using acetone cyanohydrin or trimethylsilyl cyanide, for example in an amount of from 5 to 15, preferably 10, mol percent, based on the ester. 
     Work-up can be carried out in the manner known per se. The reaction mixture is, for example, acidified with dilute mineral acid, such as 5% strength hydrochloric acid or sulfuric acid, and extracted with an organic solvent, for example methylene chloride or ethyl acetate. The organic extract can be extracted with 5-10% strength alkali metal carbonate solution, for example sodium carbonate or potassium carbonate solution. The aqueous phase is acidified and the resulting precipitate is filtered off with suction and/or extracted with methylene chloride or ethyl acetate, and the mixture is dried and concentrated. (Examples for the preparation of esters of hydroxypyrazoles and for the rearrangement of the esters are given, for example, in EP-A 282 944 and U.S. Pat. No. 4,643,757). 
     However, it is also possible to generate the “acylation product” IV in situ by reacting a pyrazole of the formula II, or an alkali metal salt thereof with a 3-(heterocyclyl)benzene derivative of the formula V in the presence of carbon monoxide, a catalyst and a base.                    
     L 2  is a leaving group, such as halogen, for example chlorine, bromine or iodine, or sulfonate, such as mesylate or triflate; preference is given to bromine or triflate. 
     The “acylation product” IV proceeds to react, directly or indirectly, to give the 1-cycloalkylpyrazolylbenzoyl derivative of the formula I. 
     Suitable catalysts are palladium-ligand complexes in which the palladium is present in oxidation state 0, metallic palladium, which has optionally been absorbed on a carrier, and preferably palladium(II) salts. The reaction with palladium(II) salts and metallic palladium is preferably carried out in the presence of complex ligands. 
     An example of a suitable palladium(0)-ligand complex is tetrakis(triphenylphosphine)palladium. 
     Metallic palladium is preferably absorbed on an inert carrier such as, for example, activated carbon, silica, alumina, barium sulfate or calcium carbonate. The reaction is preferably carried out in the presence of complex ligands such as, for example; triphenylphosphine. 
     Examples of suitable palladium(II) salts are palladium acetate and palladium chloride. The presence of complex ligands such as, for example, triphenylphosphine is preferred. 
     Suitable complex ligands for the palladium-ligand complexes, or in whose presence the reaction is preferably carried out with metallic palladium or palladium(II) salts, are tertiary phosphines whose structure is represented by the following formulae:                    
     where z is 1 to 4 and the radicals R a  to R g  are C 1 -C 6 -alkyl, C 3 -C 6 -cycloalkyl, aryl-C 1 -C 2 -alkyl or, preferably, aryl. Aryl is, for example, naphthyl and unsubstituted or substituted phenyl such as, for example, 2-tolyl and, in particular, unsubstituted phenyl. 
     The complex palladium salts can be prepared in a manner known per se starting from commercially available palladium salts such as palladium chloride or palladium acetate and the appropriate phosphines such as, for example, triphenylphosphine or 1,2-bis(diphenylphosphino)ethane. Many of the complexed palladium salts are commercially available. Preferred palladium salts are [(R)(+)2,2′-bis(diphenylphosphino)-1,1′-binaphthyl]palladium(II) chloride, bis(triphenylphosphine)palladium(II) acetate and, in particular, bis(triphenylphosphine)palladium(II) chloride. 
     The palladium catalyst is usually employed in a concentration of from 0.05 to 5 mol %, and preferably 1-3 mol %. 
     Suitable bases are tertiary amines, such as, for example, N-methylpiperidine, ethyldiisopropylamine, 1,8-bisdimethylaminonaphthalene or, in particular, triethylamine. Also suitable is alkali metal carbonate, such as sodium carbonate or potassium carbonate. However, mixtures of potassium carbonate and triethylamine are also suitable. 
     In general, from 2 to 4 molar equivalents, in particular 2 molar equivalents, of the alkali metal carbonate, and from 1 to 4 molar equivalents, in particular 2 molar equivalents, of the tertiary amine are employed, based on the 3-(heterocylyl)benzene derivative of the formula V. 
     Suitable solvents are nitriles, such as benzonitrile and acetonitrile, amides, such as dimethylformide, dimethylacetamide, tetra-C 1 -C 4 -alkylureas or N-methylpyrrolidone and, preferably, ethers, such as tetrahydrofuran and methyl tert-butyl ethers. Particular preference is given to ethers, such as 1,4-dioxane and dimethoxyethane. 
     Process B 
     Compounds of the formula I where R 12 =hydroxyl are obtained by reacting compounds of the formula I where R 12 =hydroxyl with alkylating agents, sulfonylating agents or acylating agents L 3 -R 12a (VI)                    
     L 3  is a nucleophilically displaceable leaving group, such as halogen, for example bromine or chlorine, acyloxy, for example acetyloxy or ethylcarbonyloxy, or alkylsulfonyloxy, for example methylsulfonyloxy or trifluoromethylsulfonyloxy. 
     R 12a  is C 1 -C 6 -alkyl, C 3 -C 6 -alkenyl, C 1 -C 6 -alkylsulfonyl, C 1 -C 6 -alkylcarbonyl, phenylsulfonyl or phenylcarbonyl, where the phenyl radical of the two last-mentioned substituents may be partially or fully halogenated and/or may carry one to three of the following groups: nitro, cyano, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy or C 1 -C 4 -haloalkoxy. 
     The compounds of the formula VI can be employed directly, such as, for example, in the case of the sulfonyl halides or sulfonic anhydrides, or be generated in situ, for example activated sulfonic acids (using sulfonic acid and dicyclohexylcarbonyldiimide, carbonyldiimidazole, etc.). 
     The starting materials are generally employed in equimolar amounts. However, it may also be advantageous to employ an excess of one or the other component. 
     If appropriate, it may be advantageous to carry out the reaction in the presence of a base. The reactants and the auxiliary base are advantageously employed in equimolar amounts. An excess of auxiliary base, for example from 1.5 to 3 molar equivalents, based on I, may be advantageous in certain cases. 
     Suitable auxiliary bases are tertiary alkylamines, such as triethylamine, pyridine, alkali metal carbonates, for example sodium carbonate or potassium carbonate, and alkali metal hydrides, for example sodium hydride. Preference is given to using triethylamine and pyridine. 
     Suitable solvents are, for example, chlorinated hydrocarbons, such as methylene chloride and 1,2-dichloroethane, aromatic hydrocarbons, for example toluene, xylene, chlorobenzene, ethers, such as diethyl ether, methyl tert-butyl ether, tetrahydrofuran and dioxane, polar aprotic solvents, such as acetonitrile, dimethylformamide, dimethyl sulfoxide, or esters, such as ethyl acetate, or mixtures of these. 
     In general, the reaction temperature is in the range from 0° C. to the boiling point of the reaction mixture. 
     Work-up can be carried out in the manner known per se to give the product. 
     The pyrazoles of the formula II used as starting materials are known or can be prepared by processes known per se (for example EP-A 240 001 and J. Prakt. Chem. 315, 383 (1973)). The activated benzoic acids IIIα and the benzoic acids IIIβ are likewise known or can be prepared in the manner known per se (for example WO 96/26206). Furthermore, the 3-(heterocyclyl)benzene derivatives of the formula V are known or can be prepared in the manner known per se (PCT/EP/99/03006). 
    
    
     PREPARATION EXAMPLE 
     4-[2-Methyl-3-(4,5-dihydroisoxazol-3-yl)-4-methylsulfonylbenzoyl]-1-cyclopentyl-5-hydroxy-1H-pyrazole (compound 4.6) 
     1.9 g (9.4 mmol) of dicyclohexylcarbodiimide and 1.3 g (8.8 mmol) of 1-cyclopentyl-5-hydroxy-1H-pyrazole were added to a solution of 2.5 g (8.8 mmol) of 2-methyl-3-(4,5-dihydroisoxazol-3-yl)-4-methylsulfonylbenzoic acid in 100 ml of dioxane, and the mixture was stirred at room temperature for 12 hours. Solid components were then filtered off and the filtrate was admixed with 1.5 g (10 mmol) of potassium carbonate and refluxed for 4 hours. The solvent was removed, the residue was then taken up in water and the mixture was washed with ethyl acetate, and then adjusted to pH 3 using 10% strength hydrochloric acid and extracted with methylene chloride. The solvent of the resulting organic phase was distilled off, the residue was taken up in 300 ml of aqueous potassium carbonate solution, insoluble components were filtered off, the pH was adjusted to 3 using 10% strength hydrochloric acid and the resulting precipitate was separated off and dried. Yield: 1.5 g (42% of theory) of 4-[2-methyl-3-(4,5-dihydro-isoxazol-3-yl)-4-methylsulfonylbenzoyl]-1-cyclopentyl-5-hydroxy-1H-pyrazole 
     M.p.: 135-140° C. 
     In addition to the compound above, Table 4 lists other 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I which were prepared or are preparable in a similar manner;                    
     
       
         
           
               
               
               
               
               
               
               
               
               
               
             
               
                 TABLE 4 
               
               
                   
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 physical data m.p. [° C.]; 
               
               
                 No. 
                 R 1   
                 R 2   
                 R 3   
                 Y 
                 R 4   
                 R 12   
                 R 13   
                 R 14   
                   1 H-NMR [δ in ppm] 
               
               
                   
               
             
            
               
                 4.1 
                 Cl 
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OH 
                 cyclopentyl 
                 H 
                 192-197 
               
               
                 4.2 
                 Cl 
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OCOC 6 H 5   
                 cyclopentyl 
                 H 
                 235-240 
               
               
                 4.3 
                 Cl 
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OCO(3-F—C 6 H 4 ) 
                 cyclopentyl 
                 H 
                 220-225 
               
               
                 4.4 
                 Cl 
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OCH 3   
                 cyclopentyl 
                 H 
                 195-200 
               
               
                 4.5 
                 Cl 
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OCH 2 CH 3   
                 cyclopentyl 
                 H 
                 145-150 
               
               
                 4.6 
                 CH 3   
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OH 
                 cyclopentyl 
                 H 
                 135-140 
               
               
                 4.7 
                 CH 3   
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OCO(3-F—C 6 H 4 ) 
                 cyclopentyl 
                 H 
                 1.4-2.0 (m, 8H); 2.0(s, 3H); 3.2 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 (m, 2H); 4.4(m, 2H); 4.8(m, 1H); 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 7.6-7.8(m, 7H) 
               
               
                 4.8 
                 CH 3   
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OCH(CH 3 ) 2   
                 cyclopentyl 
                 H 
                 1.2 (d, 6H); 1.4-2.0(m, 8H); 2.7 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 (s, 3H); 2.9(s, 3H); 3.3(br, 2H); 4.5 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 (t, 2H), 4.8(br, 1H); 4.9(m, 1H); 7.5 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 (s, 1H); 7.7(d, 1H); 7.9(d, 1H) 
               
               
                 4.9 
                 Cl 
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OH 
                 2-norbornyl 
                 H 
                 135-140 
               
               
                 4.10 
                 CH 3   
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OH 
                 2-norbornyl 
                 H 
                 110-115 
               
               
                 4.11 
                 Cl 
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OCOC 6 H 5   
                 2-norbornyl 
                 H 
                 200-205 
               
               
                 4.12 
                 Cl 
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OCO(3-F—C 6 H 4 ) 
                 2-norbornyl 
                 H 
                 85-90 
               
               
                 4.13 
                 CH 3   
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OCOC 6 H 5   
                 2-norbornyl 
                 H 
                 1.0-2.5(m, 10H); 2.1(s, 3H); 3.0 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 (s, 3H); 3.2(t, 2H); 4.2-4.7(m, 3H); 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 7.4-8.2(m, 8H) 
               
               
                 4.14 
                 CH 3   
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OCO(3-F—C 6 H 4 ) 
                 2-norbornyl 
                 H 
                 1.0-2.6(m, 10H); 2.1(s, 3H); 3.01 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 (s, 3H); 3.21(t, 2H), 4.3-4.7(m, 3H); 
               
               
                   
                   
                   
                   
                   
                   
                   
                   
                   
                 7.4-8.0(m, 7H) 
               
               
                 4.15 
                 Cl 
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OH 
                 2-adamantyl 
                 H 
                 120-125 
               
               
                 4.16 
                 CH 3   
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OH 
                 2-adamantyl 
                 H 
                 140-145 
               
               
                 4.17 
                 Cl 
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OH 
                 cyclopropyl 
                 H 
                 227-228 
               
               
                 4.19 
                 OCH 3   
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OH 
                 cyclopropyl 
                 H 
                 197-199 
               
               
                 4.19 
                 Cl 
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OSO 2 (4-CH 3 —C 6 H 4 ) 
                 cyclopropyl 
                 H 
                 81-82 
               
               
                 4.20 
                 Cl 
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OCH(CH 3 ) 2   
                 cyclopropyl 
                 H 
                 179-190 
               
               
                 4.21 
                 Cl 
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OCOC 6 H 5   
                 cyclopropyl 
                 H 
                 oil 
               
               
                 4.22 
                 Cl 
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OCO(3-F—C 6 H 4 ) 
                 cyclopropyl 
                 H 
                 198-200 
               
               
                 4.23 
                 OCH 3   
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OH 
                 cyclopropyl 
                 H 
                 160-161 
               
               
                 4.24 
                 CH 3   
                 H 
                 H 
                 CH 2   
                 SO 2 CH 3   
                 OH 
                 cyclopropyl 
                 H 
                 178-179 
               
               
                   
               
            
           
         
       
     
     The 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I and their agriculturally useful salts are suitable, both in the form of isomer mixtures and in the form of the pure isomers, as herbicides. The herbicidal compositions comprising compounds of the formula I control vegetation on non-crop areas very efficiently, especially at high rates of application. They act against broad-leaved weeds and harmful grasses in crops such as wheat, rice, maize, soya and cotton without causing any significant damage to the crop plants. This effect is mainly observed at low rates of application. 
     Depending on the application method used, the compounds of the formula I, or the herbicidal. compositions comprising them, can additionally be employed in a further number of crop plants for eliminating undesirable plants. Examples of suitable crops are the following: 
       Allium cepa, Ananas comosus, Arachis hypogaea, Asparagus officinalis, Beta vulgaris  spec. altissima,  Beta vulgaris  spec. rapa,  Brassica napus  var. napus,  Brassica napus  var. napobrassica,  Brassica rapa  var. silvestris,  Camellia sinensis, Carthamus tinctorius, Carya illinoinensis, Citrus limon, Citrus sinensis, Coffea arabica  ( Coffea canephora, Coffea liberica ),  Cucumis sativus, Cynodon dactylon, Daucus carota, Elaeis guineensis, Fragaria vesca, Glycine max, Gossypium hirsutum,  ( Gossypium arboreum, Gossypium herbaceum, Gossypium vitifolium ),  Helianthus annuus, Hevea brasiliensis, Hordeum vulgare, Humulus lupulus, Ipomoea batatas, Juglans regia, Lens culinaris, Linum usitatissimum, Lycopersicon lycopersicum,  Malus spec.,  Manihot esculenta, Medicago sativa,  Musa spec.,  Nicotiana tabacum  ( N. rustica ),  Olea europaea, Oryza sativa, Phaseolus lunatus, Phaseolus vulgaris, Picea abies,  Pinus spec.,  Pisum sativum, Prunus avium, Prunus persica, Pyrus communis, Ribes sylvestre, Ricinus communis, Saccharum officinarum, Secale cereale, Solanum tuberosum, Sorghum bicolor  ( S. vulgare ),  Theobroma cacao, Trifolium pratense, Triticum aestivum, Triticum durum, Vicia faba, Vitis vinifera and Zea mays.    
     In addition, the compounds of the formula I may also be used in crops which tolerate the action of herbicides owing to breeding, including genetic engineering methods. 
     The compounds of the formula I, or the herbicidal compositions comprising them, can be used for example in the form of ready-to-spray aqueous solutions, powders, suspensions, also highly-concentrated aqueous, oily or other suspensions or dispersions, emulsions, oil dispersions, pastes, dusting agents, materials for broadcasting or granules, by means of spraying, atomizing, dusting, broadcasting or watering. The use forms depend on the intended aims; in any case, they should ensure the finest distribution possible of the active compounds according to the invention. 
     The herbicidal compositions comprise a herbicidally effective amount of at least one compound of the formula I or an agriculturally useful salt of I, and auxiliaries which are customarily used for formulating of crop protection agents. 
     Essentially, suitable inert auxiliaries include: mineral oil fractions of medium to high boiling point, such as kerosene and diesel oil, furthermore coal tar oils and oils of vegetable or animal origin, aliphatic, cyclic and aromatic hydrocarbons, e.g. paraffins, tetrahydronaphthalene, alkylated naphthalenes and their derivatives, alkylated benzenes and their derivatives, alcohols such as methanol, ethanol, propanol, butanol and cyclohexanol, ketones such as cyclohexanone, or strongly polar solvents, e.g. amines such as N-methylpyrrolidone, and water. 
     Aqueous use forms can be prepared from emulsion concentrates, suspensions, pastes, wettable powders or water-dispersible granules by adding water. To prepare emulsions, pastes or oil dispersions, the substances, either as such or dissolved in an oil or solvent, can be homogenized in water by means of a wetting agent, tackifier, dispersant or emulsifier. Alternatively, it is possible to prepare concentrates comprising active compound, wetting agent, tackifier, dispersant or emulsifier and, if desired, solvent or oil, which are suitable for dilution with water. 
     Suitable surfactants (adjuvants) are the alkali metal salts, alkaline earth metal salts and ammonium salts of aromatic sulfonic acids, e.g. ligno-, phenol-, naphthalene- and dibutylnaphthalenesulfonic acid, and of fatty acids, alkyl- and alkylarylsulfonates, alkyl sulfates, lauryl ether sulfates and fatty alcohol sulfates, and salts of sulfated hexa-, hepta- and octadecanols, and also of fatty alcohol glycol ether, condensates of sulfonated naphthalene and its derivatives with formaldehyde, condensates of naphthalene, or of the naphthalenesulfonic acids with phenol and formaldehyde, polyoxyethylene octylphenol ether, ethoxylated isooctyl-, octyl- or nonylphenol, alkylphenyl or tributylphenyl polyglycol ether, alkylaryl polyether alcohols, isotridecyl alcohol, fatty alcohol/ethylene oxide condensates, ethoxylated castor oil, polyoxyethylene alkyl ethers or polyoxypropylene alkyl ethers, lauryl alcohol polyglycol ether acetate, sorbitol asters, lignin-sulfite waste liquors or methylcellulose. 
     Powders, materials for broadcasting and dusting agents can be prepared by mixing or grinding the active compounds together with a solid carrier. 
     Granules, e.g. coated granules, impregnated granules and homogeneous granules, can be prepared by binding the active compounds to solid carriers solid carriers are mineral earths, such as silicas, silica gels, silicates, talc, kaolin, limestone, lime, chalk, bole, loess, clay, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground synthetic materials, fertilizers such as ammonium sulfate, ammonium phosphate and ammonium nitrate, ureas, and products of vegetable origin, such as cereal meal, tree bark meal, wood meal and nutshell meal, cellulose powders, or other solid carriers. 
     The concentrations of the compounds of the formula I in the ready-to-use preparations can be varied within wide ranges. In general, the formulations comprise about from 0.001 to 98% by weight, preferably 0.01 to 95% by weight of at least one active compound. The active compounds are employed in a purity of from 90% to 100%, preferably 95% to 100% (according to the NMR spectrum). 
     The following formulation examples illustrate the preparation of such formulations: 
     I. 20 parts by weight of compound No. 4.6 are dissolved in a mixture composed of 80 parts by weight of alkylated benzene, 10 parts by weight of the adduct of 8 to 10 mol of ethylene oxide to 1 mol of oleic acid N-monoethanolamide, 5 parts by weight of calcium dodecylbenzenesulfonate and 5 parts by weight of the adduct of 40 mol of ethylene oxide to 1 mol of castor oil. Pouring the solution into 100,000 parts by weight of water and finely distributing it therein gives an aqueous dispersion which comprises 0.02% by weight of the active compound. 
     II. 20 parts by weight of compound no. 4.6 are dissolved in a mixture composed of 40 parts by weight of cyclohexanone, 30 parts by weight of isobutanol, 20 parts by weight of the adduct of 7 mol of ethylene oxide to 1 mol of isooctylphenol and 10 parts by weight of the adduct of 40 mol of ethylene oxide to 1 mol of castor oil. Pouring the solution into 100,000 parts by weight of water and finely distributing it therein gives an aqueous dispersion which comprises 0.02% by weight of the active compound. 
     III. 20 parts by weight of compound No. 4.6 are dissolved in a mixture composed of 25 parts by weight of cyclohexanone, 65 parts by weight of a mineral oil fraction of boiling point 210 to 280° C. and 10 parts by weight of the adduct of 40 mol of ethylene oxide to 1 mol of castor oil. Pouring the solution into 100,000 parts by weight of water and finely distributing it therein gives an aqueous dispersion which comprises 0.02% by weight of the active compound. 
     IV. 20 parts by weight of compound No. 4.6 are mixed thoroughly with 3 parts by weight of sodium diisobutylnaphthalenesulfonate, 17 parts by weight of the sodium salt of a lignosulfonic acid from a sulfite waste liquor and 60 parts by weight of pulverulent silica gel, and the mixture is ground in a hammer mill. Finely distributing the mixture in 20,000 parts by weight of water gives a spray mixture which comprises 0.1% by weight of the active compound. 
     V. 3 parts by weight of compound No. 4.6 are mixed with 97 parts by weight of finely divided kaolin. This gives a dust which comprises 3% by weight of the active compound. 
     VI. 20 parts by weight of compound No. 4.6 are mixed intimately with 2 parts by weight of calcium dodecylbenzenesulfonate, 8 parts by weight of fatty alcohol polyglycol ether, 2 parts by weight of the sodium salt of a phenol/urea/formaldehyde condensate and 68 parts by weight of a paraffinic mineral oil. This gives a stable oily dispersion. 
     VII. 1 part by weight of compound No. 4.6 is dissolved in a mixture composed of 70 parts by weight of cyclohexanone, 20 parts by weight of etboxylated isooctylphenol and 10 parts by weight of ethoxylated castor oil. This gives a stable emulsion concentrate. 
     VIII. 1 part by weight of compound No. 4.6 of the formula I is dissolved in a mixture composed of 80 parts by weight of cyclohexanone and 20 parts by weight of Wettol® EM 31 (=nonionic emulsifier based on ethoxylated castor oil). 
     This gives a stable emulsion concentrate. 
     The compounds of the formula I or the herbicidal compositions can be applied pre- or post-emergence. If the active compounds are less well tolerated by certain crop plants, application techniques may be used in which the herbicidal compositions are sprayed, with the aid of the spraying equipment, in such a way that they come into contact as little as possible, if at all, with the leaves of the sensitive crop plants, while the active compounds reach the leaves of undesirable plants growing underneath, or the bare soil surface (post-directed, lay-by). 
     The application rates of compound of the formula I are from 0.001 to 3.0, preferably 0.01 to 1.0 kg/ha of active substance (a.s.), depending on the control target, the season, the target plants and the growth stage. 
     To widen the activity spectrum and to achieve synergistic effects, the 1-cycloalkylpyrazolylbenzoyl derivatives of the formula I may be mixed with a large number of representatives of other herbicidal or growth-regulating active compound groups and applied concomitantly. Suitable components for mixtures are, for example, 1,2,4-thiadiazoles, 1,3,4-thiadiazoles, amides, aminophosphoric acid and its derivatives, aminotriazoles, anilides, (het)aryloxyalkanoic acids and their derivatives, benzoic acid and its derivatives, benzothiadiazinones, 2-((het)aroyl)-1,3-cyclohexanediones, hetaryl aryl ketones, benzylisoxazolidinones, meta-CF 3 -phenyl derivatives, carbamates, quinolinecarboxylic acid and its derivatives, chloroacetanilides, cyclohexeneone oxime ether derivatives, diazines, dichloropropionic acid and its derivatives, dihydrobenzofurans, dihydrofuran-3-ones, dinitroanilines, dinitrophenols, diphenyl ethers, dipyridyls, halocarboxylic acids and their derivatives, ureas, 3-phenyluracils, imidazoles, imidazolinones, N-phenyl-3,4,5,6-tetrahydrophthalimides, oxadiazoles, oxiranes, phenols, aryloxy- and hetaryloxyphenoxypropionic esters, phenylacetic acid and its derivatives, 2-phenylpropionic acid and its derivatives, pyrazoles, phenylpyrazoles, pyridazines, pyridinecarboxylic acid and its derivatives, pyrimidyl ethers, sulfonamides, sulfonylureas, triazines, triazinones, triazolinones, triazolecarboxamides and uracils. 
     It may furthermore be advantageous to apply the compounds of the formula I, alone or else concomitantly in combination with other herbicides, in the form of a mixture with other crop protection agents, for example together with agents for controlling pests or phytopathogenic fungi or bacteria. Also of interest is the miscibility with mineral salt solutions, which are employed for treating nutritional and trace element deficiencies. Non-phytotoxic oils and oil concentrates may also be added. 
     Use Examples 
     The herbicidal activity of the 1-cycloalkylpyrazolyl benzoyl derivatives of the formula I was demonstrated by the following greenhouse experiments: 
     The culture containers used were plastic flowerpots containing loamy sand with approximately 3.0% of humus as the substrate. The seeds of the test plants were sown separately for each species. 
     For the pre-emergence treatment, the active compounds, which had been suspended or emulsified in water, were applied directly after sowing by means of finely distributing nozzles. The containers were irrigated gently to promote germination and growth and subsequently covered with transparent plastic hoods until the plants had rooted. This cover causes uniform germination of the test plants, unless this is adversely affected by the active compounds. 
     For the post-emergence treatment, the test plants were first grown to a height of 3 to 15 cm, depending on the plant habit, and only then treated with the active compounds which had been suspended or emulsified in water. The test plants were for this purpose either sown directly and grown in the same containers, or they were first grown separately as seedlings and transplanted into the test containers a few days prior to treatment. The application rate for the post-emergence treatment was 0.5 or 0.25 kg of a.s. (active substance)/ha. 
     Depending on the species, the plants were kept at 10-25° C. or 20-35° C. The test period extended over 2 to 4 weeks. During this time, the plants were tended, and their response to the individual treatments was evaluated. 
     The evaluation was carried out using a scale from 0 to 100. 100 means no emergence of the plants, or complete destruction of at least the aerial parts and 0 means no damage, or normal course of growth. 
     The plants used in the greenhouse experiments were of the following species: 
     
       
         
           
               
               
               
             
               
                   
                   
               
               
                   
                 Scientific name 
                 Common name 
               
               
                   
                   
               
             
            
               
                   
                 
                   Brachiaria plantaginea 
                 
                 alexander grass 
               
               
                   
                 
                   Chenopodium album 
                 
                 lamb&#39;s-quarters 
               
               
                   
                 
                   Echinochloa crus-galli 
                 
                 barnyard grass 
               
               
                   
                 
                   Polygonum persicaria 
                 
                 lady&#39;s-thumb 
               
               
                   
                   
               
            
           
         
       
     
     At application rates of 0.5 or 0.25 kg/ha, the compound 4.6 (Table 4) showed very good post-emergence action against the abovementioned undesirable plants.