Patent Publication Number: US-2013253011-A1

Title: Insecticidal compounds

Description:
The present invention relates to novel triazole derivatives having insecticidal activity, to processes and intermediates for preparing them, to insecticidal, acaricidal, nematicidal or molluscicidal compositions comprising them and to methods of using them to combat and control insect, acarine, nematode or mollusc pests. 
     Accordingly, the present invention provides a compound of formula (I) 
     
       
         
         
             
             
         
       
     
     wherein
 
A 1 , A 2 , A 3  and A 4  are each independently C—X or nitrogen, wherein each X may be the same or different;
 
R 1  is hydrogen, C 1 -C 4 alkyl, H 2 NC(O)—C 1 -C 4 alkyl, or C 1 -C 4 alkylcarbonyl;
 
R 2  is hydrogen, halogen, C 1 -C 4 alkyl, C 1 -C 6  haloalkyl or cyano;
 
G 1  is oxygen or sulfur;
 
X is hydrogen, halogen, cyano, C 1 -C 4 alkyloxy, C 1 -C 4 alkyl or C 1 -C 4 haloalkyl;
 
Q 1  is aryl or heterocyclyl, each optionally substituted by one to five substituents R 3 , which may be the same or different;
 
Or Q 1  is C 1 -C 8 alkyl or C 1 -C 8 alkyl substituted by one to five R 4 , C 2 -C 8 alkenyl or C 2 -C 8 alkenyl substituted by one to five R 4 , C 2 -C 8 alkynyl or C 2 -C 8 alkynyl substituted by one to five R 4 , C 3 -C 10 cycloalkyl or C 3 -C 10 cycloalkyl substituted by one to five R 4  
 
R 3  is selected from cyano, amino, nitro, hydroxy, halogen, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 2 -C 4 alkenyl, C 2 -C 4 haloalkenyl, C 2 -C 4 alkynyl, C 2 -C 4 haloalkynyl, C 3 -C 6 cycloalkyl, C 3 -C 6 halocycloalkyl, C 1 -C 3 alkoxy, C 1 -C 3 haloalkoxy, C 1 -C 3 alkylthio, C 1 -C 3 haloalkylthio, C 1 -C 3 alkylsulfinyl, C 1 -C 3 haloalkylsulfinyl, C 1 -C 3 alkylsulfonyl, C 1 -C 3 haloalkylsulfonyl, C 1 -C 4 alkylamino, di-(C 1 -C 4 alkyl)amino, C 1 -C 4 alkylcarbonyl, C 1 -C 4 alkylcarbonyloxy, C 1 -C 4 alkoxycarbonyl, C 1 -C 4 alkylcarbonylamino and phenyl;
 
each R 4  is independently halogen, cyano, nitro, hydroxy, C 1 -C 8 alkoxy-, C 1 -C 8 haloalkoxy-, C 1 -C 8 alkylthio-, C 1 -C 8 haloalkylthio-, C 1 -C 8 alkylsulfinyl-, C 1 -C 8 haloalkylsulfinyl-, C 1 -C 8 alkylsulfonyl-, C 1 -C 8 haloalkylsulfonyl-, C 1 -C 8 alkylcarbonyl-, C 1 -C 8 alkoxycarbonyl-, aryl or aryl substituted by one to five R 3 , or heterocyclyl or heterocyclyl substituted by one to five R 3 ;
 
Q 2  is a moiety of formula (II)
 
     
       
         
         
             
             
         
       
     
     wherein
 
R 7  and R 6  are independently of each other hydrogen, cyano, halogen, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 4 alkoxy-C 1 -C 4 -alkyl, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, C 1 -C 6 alkylsulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl or C 1 -C 6 haloalkylsulfonyl;
 
R 5  is independently hydrogen, hydroxyl, amino, N—C 1 -C 6 alkylamino, N,N-di-(C 1 -C 6 alkyl)-amino, C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 alkyl substituted by one to five substituents R 9 , C 3 -C 6 Cycloalkyl substituted by one to five substituents R 9 , C 2 -C 6 alkynyl substituted by one to five substituents R 9 , C 2 -C 6 alkenyl substituted by one to five substituents R 9 , aryl or aryl substituted by one to five substituents R 10 , heteroaryl or heteroaryl substituted by one to five substituents R 10 ,
 
each R 9  is independently cyano, nitro, amino, hydroxy, halogen, N—C 1 -C 6 alkylamino, N,N-di-(C 1 -C 6 alkyl)amino, C 1 -C 6 alkoxy, C 1 -C 6 alkylthio, C 1 -C 6 alkylsulfinyl, aryl or aryl which is substituted by one to five substituents independently selected from cyano, nitro, hydroxyl, halogen, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy or C 1 -C 6 haloalkoxy, or heteroaryl or heteroaryl which is substituted by one to five substituents independently selected from cyano, nitro, hydroxy, halogen, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy or C 1 -C 6 haloalkoxy;
 
each R 10  is independently cyano, nitro, amino, hydroxy, halogen, C 1 -C 6 alkyl, C 1 -C 6 halo-alkyl, C 1 -C 4 alkoxy-C 1 -C 4 -alkyl, C 2 -C 6 alkenyl, C 2 -C 6 haloalkenyl, C 2 -C 6 alkynyl, C 2 -C 6 haloalkynyl, —C 6 cycloalkyl, —C 6 halocycloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 4 alkoxy-C 1 -C 4 -alkoxy, C 1 -C 6 alkylthio, C 1 -C 6 haloalkylthio, C 1 -C 6 alkylsulfinyl, C 1 -C 6 haloalkylsulfinyl, C 1 -C 6 alkylsulfonyl, C 1 -C 6 haloalkylsulfonyl, N—C 1 -C 6 alkylamino, N,N-di-(C 1 -C 6 alkyl)amino, N,N-di-(C 1 -C 6 alkyl)aminocarbonyl, N,N-di-(C 1 -C 6 alkyl)-aminosulfonyl, C 1 -C 6 alkylcarbonyl, C 1 -C 6 alkylcarbonyloxy, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 alkylcarbonylamino;
 
or an agrochemically acceptable salt or N-oxides thereof.
 
     The compounds of formula (I) may exist in different geometric or optical isomers (enantiomers and/or diasteroisomers) or tautomeric forms. This invention covers all such isomers and tautomers and mixtures thereof in all proportions as well as isotopic forms such as deuterated compounds. 
     Unless otherwise indicated, alkyl, on its own or as part of another group, such as alkoxy, alkylcarbonyl or alkoxycarbonyl, may be straight or branched chain and may preferably contain from 1 to 6 carbon atoms, more preferably 1 to 4, and most preferably 1 to 3. Examples of alkyl include methyl, ethyl, n-propyl, iso-propyl, n-butyl, sec-butyl, iso-butyl and tert-butyl. 
     Unless otherwise indicated, alkenyl and alkynyl, on their own or as part of another substituent, may be straight or branched chain and may preferably contain 2 to 6 carbon atoms, preferably 2 to 4, more preferably 2 to 3, and where appropriate, may be in either the ( E )- or ( Z )-configuration. Examples include vinyl, allyl and propargyl. 
     Halogen means fluorine, chlorine, bromine or iodine. 
     Haloalkyl groups may contain one or more identical or different halogen atoms, and includes, for example, trifluoromethyl, chlorodifluoromethyl, 2,2,2-trifluoroethyl or 2,2-difluoroethyl. Perfluoroalkyl groups are alkyl groups which are completely substituted with fluorine atoms and include, for example, trifluoromethyl, pentafluoroethyl and heptafluoroprop-2-yl. 
     Haloalkenyl and haloalkynyl groups may contain one or more identical or different halogen atoms, and include, for example, 2,2-difluorovinyl, 1,2-dichloro-2-fluorovinyl or 1-chloroprop-2-yn-1-yl. 
     Unless otherwise indicated, cycloalkyl may be mono- or bi-cyclic, may be optionally substituted by one or more C 1 -C 6 alkyl groups, and preferably contain 3 to 8 carbon atoms, more preferably 3 to 6 carbon atoms. Examples of cycloalkyl include cyclopropyl, 1-methylcyclopropyl, 2-methylcyclopropyl, cyclobutyl, cyclopentyl and cyclohexyl. 
     Halocycloalkyl groups may contain one or more identical or different halogen atoms, and includes, for example, 2,2-dichlorocyclopropyl, 2,2-dichloro-1-methylcyclopropyl and 2-chloro-4-fluorocyclohexyl. 
     Aryl includes phenyl, naphthyl, anthracenyl, indenyl, phenanthrenyl and biphenyl, with phenyl being preferred. 
     Heteroaryl means a mono-, bi- or tricyclic, aromatic hydrocarbon, containing 3 to 14, preferably 5 to 10, more preferably 6 to 8, ring-atoms, including 1 to 6, preferably 1 to 4, heteroatoms independently selected from nitrogen, oxygen and sulfur. Examples include furyl, thienyl, pyrrolyl, imidazolyl, pyrazolyl, thiazolyl, isothiazolyl, oxazolyl, isoxazolyl, oxadiazolyl, thiadiazolyl, triazolyl, tetrazolyl, pyridyl, pyridazinyl, pyrimidinyl, pyrazinyl, triazinyl, tetrazinyl, indolyl, benzothiophenyl, benzofuranyl, benzimidazolyl, benzothiadiazolyl, indazolyl, benzotriazolyl, benzothiazolyl, benzoxazolyl, quinolyl, isoquinolyl, phthalazinyl, quinoxalinyl, quinazolinyl, cinnolinyl and naphthyridinyl. 
     Heterocyclyl, as used herein, includes heteroaryl, and in addition may be a saturated or partially unsaturated cyclic hydrocarbon containing from 3 to 10 ring-atoms up to 4 of which are heteroatoms selected from nitrogen, oxygen and sulfur, and may be optionally substituted by one or more groups independently selected from halogen, nitro, cyano, alkyl, alkoxy. Examples of non-aromatic heterocyclyl groups are oxiranyl, azetidinyl, tetrahydrofuranyl, thiolanyl, pyrrolidinyl, pyrrolinyl, imidazolidinyl, imidazolinyl, sulfolanyl, dioxolanyl, dihydropyranyl, tetrahydropyranyl, piperidinyl, pyrazolinyl, pyrazolidinyl, dioxanyl, morpholinyl, dithianyl, thiomorpholinyl, piperazinyl, azepinyl, oxazepinyl, thiazepinyl, thiazolinyl and diazapanyl. 
     Preferred values of A 1 , A 2 , A 3 , A 4 , R 2 , R 3 , X, Q 1 , Q 2 , R 5 , R 6 , R 7  are in any combination, as set out below. 
     Preferably A 1  is C—X. 
     Preferably A 2  is C—X. 
     Preferably A 3  is C—X. 
     Preferably A 4  is C—X. 
     Preferably, X is hydrogen, halogen, cyano, methyl, trifluoromethyl or methoxy. More preferably, X is hydrogen, fluoro, chloro, cyano, trifluoromethyl or methoxy. Even more preferably, X is hydrogen, fluoro, cyano or methoxy. Most preferably, X is hydrogen, fluoro or cyano. 
     More preferably, A 1 , A 2 , A 3  and A 4  are C—X and each X is independently selected from hydrogen, halogen, cyano, methyl, trifluoromethyl and methoxy and preferably A 2  and A 3  both are CH; and A 1  and A 4  are C—X and each X is independently selected from hydrogen, halogen, cyano, methyl, trifluoromethyl and methoxy and more preferably each X is independently selected from hydrogen, fluoro, cyano and methoxy. Even more preferably, A 1 , A 2 , A 3  and A 4  are C—X and each X is independently selected from hydrogen, fluoro, cyano and methoxy. Most preferably, A 1  is CH, C—CN, C—Cl or C—F; and A 2 , A 3  and A 4  are CH or A 1 , A 2  and A 3  are CH and A 4  is CH, C—OCH 3  or C—F. Most preferred are A 1  is CH, C—CN, C—Cl or C—F; and A 2 , A 3  and A 4  are CH. Further most preferred are A 1 , A 2  and A 3  are CH and A 4  is CH, C—OCH 3  or C—F. 
     Preferably, G 1  is oxygen. 
     Preferably, R 1  is hydrogen, methyl, ethyl or acetyl. More preferably, R 1  is hydrogen, methyl or ethyl. Most preferably, R 1  is hydrogen. 
     Preferably, R 2  is hydrogen, methyl, trifluoromethyl or halogen. More preferably, R 2  is hydrogen, trifluoromethyl or halogen. Even more preferably, R 2  is hydrogen or halogen. Most preferably, R 2  is hydrogen. 
     Preferably, Q 1  is aryl or heteroaryl; each optionally substituted by one to five substituents independently selected from cyano, nitro, hydroxy, bromo, chloro, fluoro, methyl, trifluoromethyl, methoxy, trifluoromethoxy, methylthio, methylsulfinyl, methylsulfonyl and phenyl. 
     More preferably, Q 1  is phenyl, pyridyl, furanyl, thiophenyl, pyrazolyl or 1,2,3-thiadiazolyl; each optionally substituted by one to four substituents independently selected from cyano, nitro, hydroxy, bromo, chloro, fluoro, methyl, trifluoromethyl, methoxy, trifluoromethoxy, methylthio, methylsulfinyl, methylsulfonyl and phenyl. 
     Even more preferably, Q 1  is phenyl, pyridyl or pyrazolyl; each optionally substituted by one to four substituents independently selected from cyano, nitro, hydroxy, bromo, chloro, fluoro, methyl, ethyl, trifluoromethyl, methoxy, trifluoromethoxy, methylthio, methylsulfinyl, methylsulfonyl and phenyl. 
     Most preferably, Q 1  is phenyl or pyridyl; each optionally substituted by one, two or three substituents independently selected from cyano, nitro, chloro, fluoro, methyl, ethyl, trifluoromethyl, methoxy and trifluoromethoxy. 
     In a further preferred embodiment Q 1  is C 1 -C 8 alkyl or C 1 -C 8 alkyl substituted by one to five R 4 , C 2 -C 8 alkenyl or C 2 -C 8 alkenyl substituted by one to five R 4 , C 2 -C 8 alkynyl or C 2 -C 8 alkynyl substituted by one to five R 4 , C 3 -C 10 cycloalkyl or C 3 -C 10 cycloalkyl substituted by one to five R 4  and each R 4  is independently halogen, cyano, nitro, hydroxy, C 1 -C 8 alkoxy-, C 1 -C 8 haloalkoxy-, C 1 -C 8 alkylthio-, C 1 -C 8 haloalkylthio-, C 1 -C 8 alkylsulfinyl-, C 1 -C 8 haloalkylsulfinyl-, C 1 -C 8 alkylsulfonyl-, C 1 -C 8 haloalkylsulfonyl-, C 1 -C 8 alkylcarbonyl-, C 1 -C 8 alkoxycarbonyl-, aryl or aryl substituted by one to five R 3 , or heterocyclyl or heterocyclyl substituted by one to five R 3 ; and R 3  has the meaning given above and below. 
     In a further more preferred embodiment Q 1  is C 1 -C 4 alkyl or C 1 -C 4 alkyl substituted by one to five R 4 , C 2 -C 8 alkenyl or C 2 -C 8 alkenyl substituted by one to five R 4 , C 2 -C 8 alkynyl or C 2 -C 8 alkynyl substituted by one to five R 4 , C 3 -C 6 cycloalkyl or C 3 -C 6 cycloalkyl substituted by one to five R 4  and each R 4  is independently halogen, cyano, nitro, hydroxy, C 1 -C 4 alkoxy-, C 1 -C 4 haloalkoxy-, C 1 -C 4 alkylthio-, C 1 -C 4 haloalkylthio-, C 1  or aryl or aryl substituted by one to five R 3 , or heterocyclyl or heterocyclyl substituted by one to five R 3 ; and R 3  has the meaning given above and/or below or preferably R 3  is H or halogen. 
     In a further even more preferred embodiment Q 1  is C 1 -C 4 alkyl or C 1 -C 4 alkyl substituted by one to five R 4 , C 2 -C 8 alkenyl or C 2 -C 8 alkenyl substituted by one to five R 4 , C 2 -C 8 alkynyl or C 2 -C 8 alkynyl substituted by one to five R 4 , C 3 -C 6 cycloalkyl or C 3 -C 6 cycloalkyl substituted by one to five R 4  and each R 4  is independently halogen, cyano, nitro, hydroxy, C 1 -C 4 alkoxy-, C 1 -C 4 haloalkoxy-, or aryl or aryl substituted by one to five R 3 , or heterocyclyl or heterocyclyl substituted by one to five R 3 ; and R 3  has the meaning given above and/or below or preferably R 3  is H or halogen. 
     Preferred examples of Q 1  include (2,6-dichlorophenyl)-methyl, (4-methoxyphenyl)-methyl, (E)-2-isobutoxyethenyl, 1-(4-chlorophenyl)-2-methyl-propan-1-yl, 1-(4-chlorophenyl)-5-trifluoromethyl-1H-pyrazole-4-yl, 1-(4-chlorophenyl)cyclopentyl, 1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-yl, 1-methyl-1H-benzotriazole-5-yl, 1-methyl-3-tert-butyl-1H-pyrazole-5-yl, 1-methyl-3-trifluormethyl-4-chloro-1H-pyrazole-5-yl, 1-methylbenzotriazol-5-yl, 1-phenyl-5-propyl-1H-pyrazole-4-yl, 1-phenyl-5-trifluoromethyl-1H-pyrazole-4-yl, 1-phenylethyl, 1-tert-butyl-5-methyl-1H-imidazole-4-yl, 2,3-difluoro-phenyl, 2,4-difluoro-phenyl, 2,4,6-trimethylphenyl, 2,4-dichlorophenyl, 2,6-dichloro-phenyl, 2,1,3-benzoxadiazol-5-yl, 2,2,3,3,4,4,4-heptafluorobutanyl, 2,2,3,3-tetrafluoro-1-methyl-cyclobutanyl, 2,3-difluoro-phenyl, 2,4,6-trifluoro-phenyl, 2,4-difluoro-phenyl, 2,4-dimethyl-1,1,3-trioxo-2,3-dihydro-1H-1lambda*6*-benzo[d]isothiazole-5-yl, 2,5-dimethyl-furan-3-yl, 2,5-dimethylpyrazol-3-yl, 2,6-dichloro-4-pyridyl, 2-chloro-3-pyridyl, 2-chloro-4-cyano-phenyl, 2-chloro-4-methyl sulfonyl-phenyl, 2-chloro-6-methoxy-4-pyridyl, 2-chloro-Phenyl, 2-chlorothiazole-5-yl, 2-ethylhexanyl, 2-fluoro-4-trifluoromethyl-phenyl, 2-fluoro-5-chloro-Phenyl, 2-fluoro-5-trifluoromethyl-Phenyl, 2-fluoro-Phenyl, 2-isopropyl sulfanylphenyl, 2-methoxy-Phenyl, 2-methyl-4-cyano-phenyl, 2-methyl-4-fluoro-Phenyl, 2-methyl-4-nitro-phenyl, 2-methylethyl, 2-methyl-Phenyl, 2-methylsulfanylethyl, 2-phenylthiazol-4-yl, 2-phenyl-thiazole-4-yl, 2-pyridyl, 2-thienylmethyl, 2-trifluoromethoxy-Phenyl, 2-trifluoromethyl-4-fluorophenyl, 2-trifluoromethyl-Phenyl, 3-(2-chloro-phenyl)-5-methyl-isoxazole-4-yl, 3,5-difluoroPhenyl, 3,5-dimethyl-isoxazole-4-yl, 3-chloro-2,2-dimethyl-propanyl, 3-chloro-4-(isopropylsulfonyl)-thiophene-2-yl, 3-chloro-4-isopropylsulfonyl-thiophen-2-yl, 3-chloro-5-trifluoromethyl-2-pyridyl, 3-chloro-benzo[b]thiophene-2-yl, 3-chlorothiophen-2-yl, 3-chloro-thiophene-2-yl, 3-pyridyl, 3-pyridyl-N-oxide, 3-trifluoromethyl-4-fluoro-Phenyl, 3-trifluoromethylbenzyl, 4-(chloromethyl)phenyl, 4-cyano-2-methyl-phenyl, 4-cyano-Phenyl, 4-fluoro-2-chloro-Phenyl, 4-fluorobenzyl, 4-fluoro-Phenyl, 4-Methyl-[1,2,3]thiadiazole, 4-Methyl-[1,2,3]thiadiazolyl, 4-methyl-Phenyl, 4-methylsulfanyl phenyl, 4-nitro-2-chloro-Phenyl, 4-nitro-Phenyl, 4-pyridyl, 4-pyridyl-N-oxide, 4-tertButylPhenyl, 4-trifluoromethoxy-Phenyl, 4-trifluoromethyl-Phenyl, 5-chloro-1-methyl-1H-pyrazole-4-yl, 5-chloro-3-pyridyl, 5-methyl-2-phenyl-2H-[1,2,3]triazole-4-yl, 5-methyl-2-trifluoromethyl-furan-3-yl, 5-methyl-3-(2-chloro-5-fluoro-phenyl)-isoxazole-4-yl, 5-methyl-3-phenyl-isoxazole-4-yl, 5-methylisoxazol-3-yl, 5-methyl-isoxazole-3-yl, 6-(trifluoromethyl)naphthal-3-yl, 6-chloro-3-pyridyl, 6-chloropyridin-3-yl, 6-trifluoromethyl-3-pyridyl, benzo[b]thiophene-2-yl, benzo[c]thiophene-1-yl, Benzyl, but-3-en-1-yl, butanyl, cyclobutyl, cyclohexyl, Cyclopropyl, ethenyl, fluoromethyl, furanyl, isoxazole-5-yl, methoxymethyl, methyl propanoate-3-yl, naphthalene-1-yl, Phenyl, phenylethyl, quinoline-2-yl, quinoxalin-2-yl, tert-Butyl, thiophen-2-yl, thiophene-2-yl and trichloromethyl. Further preferred examples of Q 1  include (2,6-dichlorophenyl)-methyl, (4-methoxyphenyl)-methyl, (E)-2-isobutoxyethenyl, 1-(4-chlorophenyl)-2-methyl-propan-1-yl, 1-(4-chlorophenyl)cyclopentyl, 1-phenylethyl, 2,2,3,3,4,4,4-heptafluorobutanyl, 2,2,3,3-tetrafluoro-1-methyl-cyclobutanyl, 2-ethylhexanyl, 2-methylethyl, 3-chloro-2,2-dimethyl-propanyl, 3-trifluoromethylbenzyl, 4-fluorobenzyl, but-3-en-1-yl, butanyl, cyclobutyl, cyclohexyl, Cyclopropyl, ethenyl, fluoromethyl, methoxymethyl, methyl propanoate-3-yl, phenylethyl, tert-Butyl and trichloromethyl. 
     Further preferred examples of Q 1  include 1-(4-chlorophenyl)-5-trifluoromethyl-1H-pyrazole-4-yl, 1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-yl, 1-methyl-1H-benzotriazole-5-yl, 1-methyl-3-tert-butyl-1H-pyrazole-5-yl, 1-methyl-3-trifluormethyl-4-chloro-1H-pyrazole-5-yl, 1-methylbenzotriazol-5-yl, 1-phenyl-5-propyl-1H-pyrazole-4-yl, 1-phenyl-5-trifluoromethyl-1H-pyrazole-4-yl, 1-tert-butyl-5-methyl-1H-imidazole-4-yl, 2,4,6-trimethylphenyl, 2,4-dichlorophenyl, 2,6-dichloro-phenyl, 2,1,3-benzoxadiazol-5-yl, 2,3-difluoro-phenyl, 2,3-difluoro-phenyl, 2,4,6-trifluoro-phenyl, 2,4-difluoro-phenyl, 2,4-difluoro-phenyl, 2,4-dimethyl-1,1,3-trioxo-2,3-dihydro-1H-1lambda*6*-benzo[d]isothiazole-5-yl, 2,5-dimethyl-furan-3-yl, 2,5-dimethylpyrazol-3-yl, 2,6-dichloro-4-pyridyl, 2-chloro-3-pyridyl, 2-chloro-4-cyano-phenyl, 2-chloro-4-methyl sulfonyl-phenyl, 2-chloro-6-methoxy-4-pyridyl, 2-chloro-Phenyl, 2-chlorothiazole-5-yl, 2-fluoro-4-trifluoromethyl-phenyl, 2-fluoro-5-chloro-Phenyl, 2-fluoro-5-trifluoromethyl-Phenyl, 2-fluoro-Phenyl, 2-isopropylsulfanylphenyl, 2-methoxy-Phenyl, 2-methyl-4-cyano-phenyl, 2-methyl-4-fluoro-Phenyl, 2-methyl-4-nitro-phenyl, 2-methyl-Phenyl, 2-methylsulfanylethyl, 2-phenylthiazol-4-yl, 2-phenyl-thiazole-4-yl, 2-pyridyl, 2-thienylmethyl, 2-trifluoromethoxy-Phenyl, 2-trifluoromethyl-4-fluorophenyl, 2-trifluoromethyl-Phenyl, 3-(2-chloro-phenyl)-5-methyl-isoxazole-4-yl, 3,5-difluoroPhenyl, 3,5-dimethyl-isoxazole-4-yl, 3-chloro-4-(isopropylsulfonyl)-thiophene-2-yl, 3-chloro-4-isopropylsulfonyl-thiophen-2-yl, 3-chloro-5-trifluoromethyl-2-pyridyl, 3-chloro-benzo[b]thiophene-2-yl, 3-chlorothiophen-2-yl, 3-chloro-thiophene-2-yl, 3-pyridyl, 3-pyridyl-N-oxide, 3-trifluoromethyl-4-fluoro-Phenyl, 4-(chloromethyl)phenyl, 4-cyano-2-methyl-phenyl, 4-cyano-Phenyl, 4-fluoro-2-chloro-Phenyl, 4-fluoro-Phenyl, 4-Methyl-[1,2,3]thiadiazole, 4-Methyl-[1,2,3]thiadiazolyl, 4-methyl-Phenyl, 4-methylsulfanyl phenyl, 4-nitro-2-chloro-Phenyl, 4-nitro-Phenyl, 4-pyridyl, 4-pyridyl-N-oxide, 4-tertButylPhenyl, 4-trifluoromethoxy-Phenyl, 4-trifluoromethyl-Phenyl, 5-chloro-1-methyl-1H-pyrazole-4-yl, 5-chloro-3-pyridyl, 5-methyl-2-phenyl-2H-[1,2,3]triazole-4-yl, 5-methyl-2-trifluoromethyl-furan-3-yl, 5-methyl-3-(2-chloro-5-fluoro-phenyl)-isoxazole-4-yl, 5-methyl-3-phenyl-isoxazole-4-yl, 5-methylisoxazol-3-yl, 5-methyl-isoxazole-3-yl, 6-(trifluoromethyl)naphthal-3-yl, 6-chloro-3-pyridyl, 6-chloropyridin-3-yl, 6-trifluoromethyl-3-pyridyl, benzo[b]thiophene-2-yl, benzo[c]thiophene-1-yl, Benzyl, furanyl, isoxazole-5-yl, naphthalene-1-yl, Phenyl, quinoline-2-yl, quinoxalin-2-yl, thiophen-2-yl and thiophene-2-yl, 
     Further preferred examples of Q 1  include phenyl, 5-bromofuran-2-yl, 2-methoxyphenyl, 2-bromophenyl, 2-methylphenyl, 5-bromopyrid-3-yl, 3-methylpyrid-2-yl, 2-chloro-4-fluorophenyl, 4-methyl-1,2,3-thiadiazol-5-yl, 3-chloro-2-fluorophenyl, 4-nitrophenyl, 5-chloro-2-fluorophenyl, 3-chloro-2-methylphenyl, 1,2,3-thiadiazol-4-yl, 2-chloro-4-nitrophenyl, thiophen-2-yl, 2-chloro-5-nitrophenyl, 2-(trifluoromethoxy)phenyl, 2-chlorophenyl, 4-(trifluoromethoxy)phenyl, 3-chlorophenyl, 2-(trifluoromethyl)phenyl, 2-chloropyrid-3-yl, 4-(trifluoromethyl)phenyl, 2-chloropyrid-4-yl, 2-methyl-4-cyanophenyl, 6-chloropyrid-3-yl, 2,4,6-trifluorophenyl, 5-chlorothiophen-2-yl, 2,6-difluorophenyl, 3-chloro-5-(trifluoromethyl)pyrid-2-yl, 2,6-difluoro-4-cyanophenyl, 4-cyano-2-fluorophenyl, 2-chloro-6-fluorophenyl, 4-cyanophenyl, 2-methyl-3-nitrophenyl, 2-methyl-4-nitrophenyl, 2,5-dichlorophenyl, 3-methyl-4-nitrophenyl, 2,3-difluorophenyl, 2-chloro-4-cyanophenyl, 1,3-dimethyl-1H-pyrazol-5-yl, 2-fluoro-4-cyanophenyl, 2-fluorophenyl, 4-methylthiophenyl, 4-fluorophenyl, 1-methyl-3-(trifluoromethyl)pyrazol-4-yl, 2-fluoropyrid-3-yl, 4-pyridyl, 2-fluoro-3-(trifluoromethyl)phenyl, 1,3-dimethylpyrazol-4-yl, 2-fluoro-5-(trifluoromethyl)-phenyl, 4-methylphenyl, 4-fluoro-3-(trifluoromethyl)phenyl, 4-fluoro-2-methylphenyl, furan-2-yl, and 2,4-difluorophenyl, cyclopropyl, benzyl. 
     In a further preferred embodiment Q 2  is a moiety of formula (II) wherein the substituents R 5 , R 6  and R 7  have the following meaning: R 7  and R 6  are independently hydrogen, cyano, halogen, C 1 -C 6 alkyl, C 1 -C 6  perfluoroalkyl, C 1 -C 6  perfluoroalkylthio, C 1 -C 6  perfluoroalkylsulfinyl or C 1 -C 6 -perfluoroalkylsulfonyl preferably independently C 1 -C 4  perfluoroalkyl, C 1 -C 4  perfluoroalkylthio, C 1 -C 4 -perfluoroalkylsulfinyl or C 1 -C 4 -per-fluoroalkylsulfonyl even more preferably independently C 1 -C 4 -perfluoroalkyl, C 1 -C 4 -perfluoroalkylthio, or C 1 -C 4 -perfluoroalkylsulfonyl most preferably independently trifluoromethyl or perfluoroethyl or trifluoromethylthio or perfluoroethylthio or trifluoromethylsulfonyl or perfluoroethylsulfonyl. 
     More preferably R 7  and R 6  are independently cyano, halogen, C 1 -C 6 alkyl, C 1 -C 6 -perfluoroalkyl preferably independently C 1 -C 6 -perfluoroalkyl even more preferably independently trifluoromethyl or perfluoroethyl. 
     Even more preferably R 7  and R 6  are independently halogen, C 1 -C 6  perfluoroalkyl. 
     Most preferably R 6  is trifluoromethyl. 
     Most preferably R 7  is perfluoroethyl. 
     Preferably R 5  is hydrogen, C 1 -C 6 haloalkyl, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, phenyl or phenyl substituted by one to five substituents R 10 , which may be the same or different, pyridyl or pyridyl substituted by one to five substituents R 10 , which may be the same or different 
     More preferably R 5  is hydrogen, C 1 -C 6 haloalkyl, C 1 -C 6 alkyl; Even more preferably R 5  is C 1 -C 6 alkyl preferably C 1 -C 4 alkyl; 
     In a further preferred embodiment Q 2  is a moiety of formula (II) wherein the substituents R 5 , R 6  and R 7  have the following meaning: R 7  and R 6  are independently cyano, halogen, C 1 -C 6 alkyl, C 1 -C 6  perfluoroalkyl, C 1 -C 6  perfluoroalkylthio, C 1 -C 6  perfluoroalkylsulfinyl or C 1 -C 6 -perfluoroalkylsulfonyl; and R 5  is C 1 -C 6 haloalkyl or C 1 -C 6 alkyl; Even more preferably R 5  is C 1 -C 6 alkyl preferably C 1 -C 4 alkyl; 
     In a preferred embodiment Q 2  is 2-Methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl 
     A preferred embodiment (E1) the substituents in the compounds of Formula (I) have the following meaning: 
     R 1  is hydrogen, methyl, ethyl or acetyl;
 
R 2  is hydrogen, methyl, trifluoromethyl or halogen;
 
G 1  is oxygen;
 
Q 1  is aryl or heteroaryl; each optionally substituted by one to five substituents independently selected from cyano, nitro, hydroxy, bromo, chloro, fluoro, methyl, trifluoromethyl, methoxy, trifluoromethoxy, methylthio, methylsulfinyl, methylsulfonyl and phenyl;
 
Q 2  is a moiety of formula (II)
 
     
       
         
         
             
             
         
       
     
     wherein
 
R 5  is hydrogen, C 1 -C 6 haloalkyl, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, phenyl or phenyl substituted by one to five substituents R 10 , which may be the same or different, pyridyl or pyridyl substituted by one to five substituents R 10 , which may be the same or different;
 
R 7  and R 6  are independently hydrogen, cyano, halogen, C 1 -C 6 alkyl, C 1 -C 6  perfluoroalkyl, C 1 -C 6  perfluoroalkylthio, C 1 -C 6  perfluoroalkylsulfinyl or C 1 -C 6 -perfluoroalkylsulfonyl preferably independently C 1 -C 4  perfluoroalkyl, C 1 -C 4  perfluoroalkylthio, C 1 -C 4 -perfluoroalkylsulfinyl or C 1 -C 4 -perfluoroalkylsulfonyl even more preferably independently C 1 -C 4 -perfluoroalkyl, C 1 -C 4 -perfluoroalkylthio, or C 1 -C 4 -perfluoroalkylsulfonyl;
 
     A preferred embodiment (E2) the substituents in the compounds of formula (I) have the following meaning: 
     R 1  is hydrogen, methyl or ethyl;
 
R 2  is hydrogen, trifluoromethyl or halogen;
 
Q 1  is phenyl, pyridyl, furanyl, thiophenyl, pyrazolyl or 1,2,3-thiadiazolyl; each optionally substituted by one to four substituents independently selected from cyano, nitro, hydroxy, bromo, chloro, fluoro, methyl, trifluoromethyl, methoxy, trifluoromethoxy, methylthio, methylsulfinyl, methylsulfonyl and phenyl;
 
Q 2  is a moiety of formula (II)
 
     
       
         
         
             
             
         
       
     
     wherein
 
R 5  is hydrogen, C 1 -C 6 haloalkyl, C 1 -C 6 alkyl;
 
R 7  and R 6  are independently cyano, halogen, C 1 -C 6 alkyl, C 1 -C 6 -perfluoroalkyl;
 
     A preferred embodiment (E3) the substituents in the compounds of formula (I) have the following meaning: 
     R 1  is hydrogen, methyl or ethyl;
 
R 2  is hydrogen or halogen;
 
Q 1  is phenyl, pyridyl or pyrazolyl; each optionally substituted by one to four substituents independently selected from cyano, nitro, hydroxy, bromo, chloro, fluoro, methyl, ethyl, trifluoromethyl, methoxy, trifluoromethoxy, methylthio, methylsulfinyl, methylsulfonyl and phenyl;
 
Q 2  is a moiety of formula (II)
 
     
       
         
         
             
             
         
       
     
     wherein
 
R 5  preferably C 1 -C 4 alkyl;
 
R 7  and R 6  are independently C 1 -C 6 -perfluoroalky;
 
A preferred embodiment (E4) the substituents in the compounds of formula (I) have the following meaning:
 
R 1  is hydrogen;
 
R 2  is hydrogen
 
     Q 1  is phenyl or pyridyl; each optionally substituted by one, two or three substituents independently selected from cyano, nitro, chloro, fluoro, methyl, ethyl, trifluoromethyl, methoxy and trifluoromethoxy; Q 2  is 2-Methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl. 
     A preferred embodiment (E5) the substituents in the compounds of Formula (I) have the following meaning: 
     R 1  is hydrogen, methyl, ethyl or acetyl;
 
R 2  is hydrogen, methyl, trifluoromethyl or halogen;
 
G 1  is oxygen;
 
Q 1  is C 1 -C 4 alkyl or C 1 -C 4 alkyl substituted by one to five R 4 , C 2 -C 8 alkenyl or C 2 -C 8 alkenyl substituted by one to five R 4 , C 2 -C 8 alkynyl or C 2 -C 8 alkynyl substituted by one to five R 4 , C 3 -C 6 cycloalkyl or C 3 -C 6 cycloalkyl substituted by one to five R 4  and each R 4  is independently halogen, cyano, nitro, hydroxy, C 1 -C 4 alkoxy-, C 1 -C 4 haloalkoxy-, or aryl or aryl substituted by one to five R 3 , or heterocyclyl or heterocyclyl substituted by one to five R 3 ; and R 3  has the meaning given above and/or below or preferably R 3  is H or halogen;
 
Q 2  is a moiety of formula (II)
 
     
       
         
         
             
             
         
       
     
     wherein
 
R 5  is hydrogen, C 1 -C 6 haloalkyl, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, phenyl or phenyl substituted by one to five substituents R 10 , which may be the same or different, pyridyl or pyridyl substituted by one to five substituents R 10 , which may be the same or different;
 
R 7  and R 6  are independently hydrogen, cyano, halogen, C 1 -C 6 alkyl, C 1 -C 6  perfluoroalkyl, C 1 -C 6  perfluoroalkylthio, C 1 -C 6  perfluoroalkylsulfinyl or C 1 -C 6 -perfluoroalkylsulfonyl preferably independently C 1 -C 4  perfluoroalkyl, C 1 -C 4  perfluoroalkylthio, C 1 -C 4 -perfluoroalkylsulfinyl or C 1 -C 4 -perfluoroalkylsulfonyl even more preferably independently C 1 -C 4 -perfluoroalkyl, C 1 -C 4 -perfluoroalkylthio, or C 1 -C 4 -perfluoroalkylsulfonyl;
 
     A preferred embodiment (E6) the substituents in the compounds of formula (I) have the following meaning: 
     R 1  is hydrogen, methyl or ethyl;
 
R 2  is hydrogen, trifluoromethyl or halogen;
 
Q 1  is C 1 -C 4 alkyl or C 1 -C 4 alkyl substituted by one to five R 4 , C 2 -C 8 alkenyl or C 2 -C 8 alkenyl substituted by one to five R 4 , C 2 -C 8 alkynyl or C 2 -C 8 alkynyl substituted by one to five R 4 , C 3 -C 6 cycloalkyl or C 3 -C 6 cycloalkyl substituted by one to five R 4  and each R 4  is independently halogen, cyano, nitro, hydroxy, C 1 -C 4 alkoxy-, C 1 -C 4 haloalkoxy-, or aryl or aryl substituted by one to five R 3 , or heterocyclyl or heterocyclyl substituted by one to five R 3 ; and R 3  has the meaning given above and/or below or preferably R 3  is H or halogen;
 
Q 2  is a moiety of formula (II)
 
     
       
         
         
             
             
         
       
     
     wherein
 
R 5  is hydrogen, C 1 -C 6 haloalkyl, C 1 -C 6 alkyl;
 
R 7  and R 6  are independently cyano, halogen, C 1 -C 6 alkyl, C 1 -C 6 -perfluoroalkyl;
 
     A preferred embodiment (E7) the substituents in the compounds of formula (I) have the following meaning: 
     R 1  is hydrogen, methyl or ethyl;
 
R 2  is hydrogen or halogen;
 
Q 1  is C 1 -C 4 alkyl or C 1 -C 4 alkyl substituted by one to five R 4 , C 2 -C 8 alkenyl or C 2 -C 8 alkenyl substituted by one to five R 4 , C 2 -C 8 alkynyl or C 2 -C 8 alkynyl substituted by one to five R 4 , C 3 -C 6 cycloalkyl or C 3 -C 6 cycloalkyl substituted by one to five R 4  and each R 4  is independently halogen, cyano, nitro, hydroxy, C 1 -C 4 alkoxy-, C 1 -C 4 haloalkoxy-, or aryl or aryl substituted by one to five R 3 , or heterocyclyl or heterocyclyl substituted by one to five R 3 ; and R 3  has the meaning given above and/or below or preferably R 3  is H or halogen;
 
Q 2  is a moiety of formula (II)
 
     
       
         
         
             
             
         
       
     
     wherein
 
R 5  preferably C 1 -C 4 alkyl;
 
R 7  and R 6  are independently C 1 -C 6 -perfluoroalky;
 
     A preferred embodiment (E8) the substituents in the compounds of formula (I) have the following meaning: 
     R 1  is hydrogen;
 
R 2  is hydrogen
 
Q 1  is C 1 -C 4 alkyl or C 1 -C 4 alkyl substituted by one to five R 4 , C 2 -C 8 alkenyl or C 2 -C 8 alkenyl substituted by one to five R 4 , C 2 -C 8 alkynyl or C 2 -C 8 alkynyl substituted by one to five R 4 , C 3 -C 6 cycloalkyl or C 3 -C 6 cycloalkyl substituted by one to five R 4  and each R 4  is independently halogen, cyano, nitro, hydroxy, C 1 -C 4 alkoxy-, C 1 -C 4 haloalkoxy-, or aryl or aryl substituted by one to five R 3 , or heterocyclyl or heterocyclyl substituted by one to five R 3 ; and R 3  has the meaning given above and/or below or preferably R 3  is H or halogen;
 
Q 2  is 2-Methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl.
 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2 , A 3  and A 4  are C—X and each X is independently selected from hydrogen, halogen, cyano, methyl, trifluoromethyl and methoxy and the other substituents have the meaning as in the Embodiment (E1) 
     A preferred embodiment are compounds of formula (I) wherein A 2  and A 3  both are CH; and A 1  and A 4  are C—X and each X is independently selected from hydrogen, halogen, cyano, methyl, trifluoromethyl and methoxy and more preferably each X is independently selected from hydrogen, fluoro, cyano and methoxy and the other substituents have the meaning as in the Embodiment (E1) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2 , A 3  and A 4  are C—X and each X is independently selected from hydrogen, fluoro, cyano and methoxy and the other substituents have the meaning as in the Embodiment (E1) 
     A preferred embodiment are compounds of formula (I) wherein A 1  is CH, C—CN, C—Cl or C—F; and A 2 , A 3  and A 4  are CH or A 1 , A 2  and A 3  are CH and A 4  is CH, C—OCH 3  or C—F and the other substituents have the meaning as in the Embodiment (E1) 
     A preferred embodiment are compounds of formula (I) wherein A 1  is CH, C—CN, C—Cl or C—F; and A 2 , A 3  and A 4  are CH methoxy and the other substituents have the meaning as in the Embodiment (E1) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2  and A 3  are CH and A 4  is CH, C—OCH 3  or C—F and the other substituents have the meaning as in the Embodiment (E1) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2 , A 3  and A 4  are C—X and each X is independently selected from hydrogen, halogen, cyano, methyl, trifluoromethyl and methoxy and the other substituents have the meaning as in the Embodiment (E2) 
     A preferred embodiment are compounds of formula (I) wherein A 2  and A 3  both are CH; and A 1  and A 4  are C—X and each X is independently selected from hydrogen, halogen, cyano, methyl, trifluoromethyl and methoxy and more preferably each X is independently selected from hydrogen, fluoro, cyano and methoxy and the other substituents have the meaning as in the Embodiment (E2) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2 , A 3  and A 4  are C—X and each X is independently selected from hydrogen, fluoro, cyano and methoxy and the other substituents have the meaning as in the Embodiment (E2) 
     A preferred embodiment are compounds of formula (I) wherein A 1  is CH, C—CN, C—Cl or C—F; and A 2 , A 3  and A 4  are CH or A 1 , A 2  and A 3  are CH and A 4  is CH, C—OCH 3  or C—F and the other substituents have the meaning as in the Embodiment (E2) 
     A preferred embodiment are compounds of formula (I) wherein A 1  is CH, C—CN, C—Cl or C—F; and A 2 , A 3  and A 4  are CH methoxy and the other substituents have the meaning as in the Embodiment (E2) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2  and A 3  are CH and A 4  is CH, C—OCH 3  or C—F and the other substituents have the meaning as in the Embodiment (E2) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2 , A 3  and A 4  are C—X and each X is independently selected from hydrogen, halogen, cyano, methyl, trifluoromethyl and methoxy and the other substituents have the meaning as in the Embodiment (E3) 
     A preferred embodiment are compounds of formula (I) wherein A 2  and A 3  both are CH; and A 1  and A 4  are C—X and each X is independently selected from hydrogen, halogen, cyano, methyl, trifluoromethyl and methoxy and more preferably each X is independently selected from hydrogen, fluoro, cyano and methoxy and the other substituents have the meaning as in the Embodiment (E3) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2 , A 3  and A 4  are C—X and each X is independently selected from hydrogen, fluoro, cyano and methoxy and the other substituents have the meaning as in the Embodiment (E3) 
     A preferred embodiment are compounds of formula (I) wherein A 1  is CH, C—CN, C—Cl or C—F; and A 2 , A 3  and A 4  are CH or A 1 , A 2  and A 3  are CH and A 4  is CH, C—OCH 3  or C—F and the other substituents have the meaning as in the Embodiment (E3) 
     A preferred embodiment are compounds of formula (I) wherein A 1  is CH, C—CN, C—Cl or C—F; and A 2 , A 3  and A 4  are CH methoxy and the other substituents have the meaning as in the Embodiment (E3) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2  and A 3  are CH and A 4  is CH, C—OCH 3  or C—F and the other substituents have the meaning as in the Embodiment (E3) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2 , A 3  and A 4  are C—X and each X is independently selected from hydrogen, halogen, cyano, methyl, trifluoromethyl and methoxy and the other substituents have the meaning as in the Embodiment (E4) 
     A preferred embodiment are compounds of formula (I) wherein A 2  and A 3  both are CH; and A 1  and A 4  are C—X and each X is independently selected from hydrogen, halogen, cyano, methyl, trifluoromethyl and methoxy and more preferably each X is independently selected from hydrogen, fluoro, cyano and methoxy and the other substituents have the meaning as in the Embodiment (E4) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2 , A 3  and A 4  are C—X and each X is independently selected from hydrogen, fluoro, cyano and methoxy and the other substituents have the meaning as in the Embodiment (E4) 
     A preferred embodiment are compounds of formula (I) wherein A 1  is CH, C—CN, C—Cl or C—F; and A 2 , A 3  and A 4  are CH or A 1 , A 2  and A 3  are CH and A 4  is CH, C—OCH 3  or C—F and the other substituents have the meaning as in the Embodiment (E4) 
     A preferred embodiment are compounds of formula (I) wherein A 1  is CH, C—CN, C—Cl or C—F; and A 2 , A 3  and A 4  are CH methoxy and the other substituents have the meaning as in the Embodiment (E4) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2  and A 3  are CH and A 4  is CH, C—OCH 3  or C—F and the other substituents have the meaning as in the Embodiment (E4) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2 , A 3  and A 4  are C—X and each X is independently selected from hydrogen, halogen, cyano, methyl, trifluoromethyl and methoxy and the other substituents have the meaning as in the Embodiment (E5) 
     A preferred embodiment are compounds of formula (I) wherein A 2  and A 3  both are CH; and A 1  and A 4  are C—X and each X is independently selected from hydrogen, halogen, cyano, methyl, trifluoromethyl and methoxy and more preferably each X is independently selected from hydrogen, fluoro, cyano and methoxy and the other substituents have the meaning as in the Embodiment (E5) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2 , A 3  and A 4  are C—X and each X is independently selected from hydrogen, fluoro, cyano and methoxy and the other substituents have the meaning as in the Embodiment (E5) 
     A preferred embodiment are compounds of formula (I) wherein A 1  is CH, C—CN, C—Cl or C—F; and A 2 , A 3  and A 4  are CH or A 1 , A 2  and A 3  are CH and A 4  is CH, C—OCH 3  or C—F and the other substituents have the meaning as in the Embodiment (E5) 
     A preferred embodiment are compounds of formula (I) wherein A 1  is CH, C—CN, C—Cl or C—F; and A 2 , A 3  and A 4  are CH methoxy and the other substituents have the meaning as in the Embodiment (E5) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2  and A 3  are CH and A 4  is CH, C—OCH 3  or C—F and the other substituents have the meaning as in the Embodiment (E5) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2 , A 3  and A 4  are C—X and each X is independently selected from hydrogen, halogen, cyano, methyl, trifluoromethyl and methoxy and the other substituents have the meaning as in the Embodiment (E6) 
     A preferred embodiment are compounds of formula (I) wherein A 2  and A 3  both are CH; and A 1  and A 4  are C—X and each X is independently selected from hydrogen, halogen, cyano, methyl, trifluoromethyl and methoxy and more preferably each X is independently selected from hydrogen, fluoro, cyano and methoxy and the other substituents have the meaning as in the Embodiment (E6) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2 , A 3  and A 4  are C—X and each X is independently selected from hydrogen, fluoro, cyano and methoxy and the other substituents have the meaning as in the Embodiment (E6) 
     A preferred embodiment are compounds of formula (I) wherein A 1  is CH, C—CN, C—Cl or C—F; and A 2 , A 3  and A 4  are CH or A 1 , A 2  and A 3  are CH and A 4  is CH, C—OCH 3  or C—F and the other substituents have the meaning as in the Embodiment (E6) 
     A preferred embodiment are compounds of formula (I) wherein A 1  is CH, C—CN, C—Cl or C—F; and A 2 , A 3  and A 4  are CH methoxy and the other substituents have the meaning as in the Embodiment (E6) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2  and A 3  are CH and A 4  is CH, C—OCH 3  or C—F and the other substituents have the meaning as in the Embodiment (E6) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2 , A 3  and A 4  are C—X and each X is independently selected from hydrogen, halogen, cyano, methyl, trifluoromethyl and methoxy and the other substituents have the meaning as in the Embodiment (E7) 
     A preferred embodiment are compounds of formula (I) wherein A 2  and A 3  both are CH; and A 1  and A 4  are C—X and each X is independently selected from hydrogen, halogen, cyano, methyl, trifluoromethyl and methoxy and more preferably each X is independently selected from hydrogen, fluoro, cyano and methoxy and the other substituents have the meaning as in the Embodiment (E7) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2 , A 3  and A 4  are C—X and each X is independently selected from hydrogen, fluoro, cyano and methoxy and the other substituents have the meaning as in the Embodiment (E7) 
     A preferred embodiment are compounds of formula (I) wherein A 1  is CH, C—CN, C—Cl or C—F; and A 2 , A 3  and A 4  are CH or A 1 , A 2  and A 3  are CH and A 4  is CH, C—OCH 3  or C—F and the other substituents have the meaning as in the Embodiment (E7) 
     A preferred embodiment are compounds of formula (I) wherein A 1  is CH, C—CN, C—Cl or C—F; and A 2 , A 3  and A 4  are CH methoxy and the other substituents have the meaning as in the Embodiment (E7) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2  and A 3  are CH and A 4  is CH, C—OCH 3  or C—F and the other substituents have the meaning as in the Embodiment (E7) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2 , A 3  and A 4  are C—X and each X is independently selected from hydrogen, halogen, cyano, methyl, trifluoromethyl and methoxy and the other substituents have the meaning as in the Embodiment (E8) 
     A preferred embodiment are compounds of formula (I) wherein A 2  and A 3  both are CH; and A 1  and A 4  are C—X and each X is independently selected from hydrogen, halogen, cyano, methyl, trifluoromethyl and methoxy and more preferably each X is independently selected from hydrogen, fluoro, cyano and methoxy and the other substituents have the meaning as in the Embodiment (E8) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2 , A 3  and A 4  are C—X and each X is independently selected from hydrogen, fluoro, cyano and methoxy and the other substituents have the meaning as in the Embodiment (E8) 
     A preferred embodiment are compounds of formula (I) wherein A 1  is CH, C—CN, C—Cl or C—F; and A 2 , A 3  and A 4  are CH or A 1 , A 2  and A 3  are CH and A 4  is CH, C—OCH 3  or C—F and the other substituents have the meaning as in the Embodiment (E8) 
     A preferred embodiment are compounds of formula (I) wherein A 1  is CH, C—CN, C—Cl or C—F; and A 2 , A 3  and A 4  are CH methoxy and the other substituents have the meaning as in the Embodiment (E8) 
     A preferred embodiment are compounds of formula (I) wherein A 1 , A 2  and A 3  are CH and A 4  is CH, C—OCH 3  or C—F and the other substituents have the meaning as in the Embodiment (E8) 
     A preferred embodiment (Ea) are compounds of formula (I) wherein A 1  is C—CN, and A 2 , A 3 , and A 4  are CH. 
     A preferred embodiment (Eb) are compounds of formula (I) wherein A 4  is C—F, and A 1 , A 2 , and A 3  are CH. 
     A preferred embodiment (Ec) are compounds of formula (I) wherein A 4  is C-OMe, A 1 , A 2  and A 3  are CH. 
     A preferred embodiment (Ed) are compounds of formula (I) wherein A 1 , A 2 , A 3 , A 4  are CH. 
     A preferred embodiment (Ee) are compounds of formula (I) wherein A 1  is C—Cl, A 2 , A 3  and A 4  are CH. 
     A preferred embodiment (Ef) are compounds of formula (I) wherein A 1  is C—F, and A 2 , A 3 , and A 4  are CH. 
     A preferred embodiment (Eg) are compounds of formula (I) wherein A 1  is C—CF 3 , and A 2 , A 3 , and A 4  are CH. 
     A preferred embodiment (Eh) are compounds of formula (I) wherein A 4  is N, A 1 , A 2  and A 3  are CH. 
     A preferred embodiment (E1) are compounds of formula (I) wherein A 4  is N, A 1  is CN, A 2  and A 3  are CH. 
     A preferred embodiment (Ej) are compounds of formula (j) wherein A 4  is N, A 1  is F, A 2  and A 3  are CH. 
     A preferred embodiment (Ea1) are compounds of formula (I) wherein A 1  is C—CN, and A 2 , A 3 , and A 4  are CH and the other substituents have the meaning as given in the embodiment of (E1). 
     A preferred embodiment (Eb1) are compounds of formula (I) wherein A 4  is C—F, and A 1 , A 2 , and A 3  are CH and the other substituents have the meaning as given in the embodiment of (E1). 
     A preferred embodiment (Ec1) are compounds of formula (I) wherein A 4  is C-OMe, A 1 , A 2  and A 3  are CH and the other substituents have the meaning as given in the embodiment of (E1). 
     A preferred embodiment (Ed1) are compounds of formula (I) wherein A 1 , A 2 , A 3 , A 4  are CH and the other substituents have the meaning as given in the embodiment of (E1). 
     A preferred embodiment (Ee1) are compounds of formula (I) wherein A 1  is C—Cl, A 2 , A 3  and A 4  are CH and the other substituents have the meaning as given in the embodiment of (E1). 
     A preferred embodiment (Ef1) are compounds of formula (I) wherein A 1  is C—F, and A 2 , A 3 , and A 4  are CH and the other substituents have the meaning as given in the embodiment of (E1). 
     A preferred embodiment (Eg1) are compounds of formula (I) wherein A 1  is C—CF 3 , and A 2 , A 3 , and A 4  are CH and the other substituents have the meaning as given in the embodiment of (E1). 
     A preferred embodiment (Eh1) are compounds of formula (I) wherein A 4  is N, A 1 , A 2  and A 3  are CH and the other substituents have the meaning as given in the embodiment of (E1). 
     A preferred embodiment (Ei1) are compounds of formula (I) wherein A 4  is N, A 1  is CN, A 2  and A 3  are CH and the other substituents have the meaning as given in the embodiment of (E1). 
     A preferred embodiment (Ej1) are compounds of formula (I) wherein A 4  is N, A 1  is F, A 2  and A 3  are CH and the other substituents have the meaning as given in the embodiment of (E1). 
     A preferred embodiment (Ea2) are compounds of formula (I) wherein A 1  is C—CN, and A 2 , A 3 , and A 4  are CH and the other substituents have the meaning as given in the embodiment of (E2). 
     A preferred embodiment (Eb2) are compounds of formula (I) wherein A 4  is C—F, and A 1 , A 2 , and A 3  are CH and the other substituents have the meaning as given in the embodiment of (E2). 
     A preferred embodiment (Ec2) are compounds of formula (I) wherein A 4  is C-OMe, A 1 , A 2  and A 3  are CH and the other substituents have the meaning as given in the embodiment of (E2). 
     A preferred embodiment (Ed2) are compounds of formula (I) wherein A 1 , A 2 , A 3 , A 4  are CH and the other substituents have the meaning as given in the embodiment of (E2). 
     A preferred embodiment (Ee2) are compounds of formula (I) wherein A 1  is C—Cl, A 2 , A 3  and A 4  are CH and the other substituents have the meaning as given in the embodiment of (E2). 
     A preferred embodiment (Ef2) are compounds of formula (If) wherein A 1  is C—F, and A 2 , A 3 , and A 4  are CH and the other substituents have the meaning as given in the embodiment of (E2). 
     A preferred embodiment (Eg2) are compounds of formula (I) wherein A 1  is C—CF 3 , and A 2 , A 3 , and A 4  are CH and the other substituents have the meaning as given in the embodiment of (E2). 
     A preferred embodiment (Eh2) are compounds of formula (I) wherein A 4  is N, A 1 , A 2  and A 3  are CH and the other substituents have the meaning as given in the embodiment of (E2). 
     A preferred embodiment (Ei2) are compounds of formula (I) wherein A 4  is N, A 1  is CN, A 2  and A 3  are CH and the other substituents have the meaning as given in the embodiment of (E2). 
     A preferred embodiment (Ej2) are compounds of formula (I) wherein A 4  is N, A 1  is F, A 2  and A 3  are CH and the other substituents have the meaning as given in the embodiment of (E2). 
     A preferred embodiment (Ea3) are compounds of formula (I) wherein A 1  is C—CN, and A 2 , A 3 , and A 4  are CH and the other substituents have the meaning as given in the embodiment of (E3). 
     A preferred embodiment (Eb3) are compounds of formula (I) wherein A 4  is C—F, and A 1 , A 2 , and A 3  are CH and the other substituents have the meaning as given in the embodiment of (E3). 
     A preferred embodiment (Ec3) are compounds of formula (I) wherein A 4  is C-OMe, A 1 , A 2  and A 3  are CH and the other substituents have the meaning as given in the embodiment of (E3). 
     A preferred embodiment (Ed3) are compounds of formula (I) wherein A 1 , A 2 , A 3 , A 4  are CH and the other substituents have the meaning as given in the embodiment of (E3). 
     A preferred embodiment (Ee3) are compounds of formula (I) wherein A 1  is C—Cl, A 2 , A 3  and A 4  are CH and the other substituents have the meaning as given in the embodiment of (E3). 
     A preferred embodiment (Ef3) are compounds of formula (I) wherein A 1  is C—F, and A 2 , A 3 , and A 4  are CH and the other substituents have the meaning as given in the embodiment of (E3). 
     A preferred embodiment (Eg3) are compounds of formula (I) wherein A 1  is C—CF 3 , and A 2 , A 3 , and A 4  are CH and the other substituents have the meaning as given in the embodiment of (E3). 
     A preferred embodiment (Eh3) are compounds of formula (I) wherein A 4  is N, A 1 , A 2  and A 3  are CH and the other substituents have the meaning as given in the embodiment of (E3). 
     A preferred embodiment (Ei3) are compounds of formula (I) wherein A 4  is N, A 1  is CN, A 2  and A 3  are CH and the other substituents have the meaning as given in the embodiment of (E3). 
     A preferred embodiment (Ej3) are compounds of formula (I) wherein A 4  is N, A 1  is F, A 2  and A 3  are CH and the other substituents have the meaning as given in the embodiment of (E3). 
     A preferred embodiment (Ea4) are compounds of formula (I) wherein A 1  is C—CN, and A 2 , A 3 , and A 4  are CH and the other substituents have the meaning as given in the embodiment of (E4). 
     A preferred embodiment (Eb4) are compounds of formula (I) wherein A 4  is C—F, and A 1 , A 2 , and A 3  are CH and the other substituents have the meaning as given in the embodiment of (E4). 
     A preferred embodiment (Ec4) are compounds of formula (I) wherein A 4  is C-OMe, A 1 , A 2  and A 3  are CH and the other substituents have the meaning as given in the embodiment of (E4). 
     A preferred embodiment (Ed4) are compounds of formula (I) wherein A 1 , A 2 , A 3 , A 4  are CH and the other substituents have the meaning as given in the embodiment of (E4). 
     A preferred embodiment (Ee4) are compounds of formula (I) wherein A 1  is C—Cl, A 2 , A 3  and A 4  are CH and the other substituents have the meaning as given in the embodiment of (E4). 
     A preferred embodiment (Ef4) are compounds of formula (I) wherein A 1  is C—F, and A 2 , A 3 , and A 4  are CH and the other substituents have the meaning as given in the embodiment of (E4). 
     A preferred embodiment (Eg4) are compounds of formula (I) wherein A 1  is C—CF 3 , and A 2 , A 3 , and A 4  are CH and the other substituents have the meaning as given in the embodiment of (E4). 
     A preferred embodiment (Eh4) are compounds of formula (I) wherein A 4  is N, A 1 , A 2  and A 3  are CH and the other substituents have the meaning as given in the embodiment of (E4). 
     A preferred embodiment (Ei4) are compounds of formula (I) wherein A 4  is N, A 1  is CN, A 2  and A 3  are CH and the other substituents have the meaning as given in the embodiment of (E4). 
     A preferred embodiment (Ej4) are compounds of formula (I) wherein A 4  is N, A 1  is F, A 2  and A 3  are CH and the other substituents have the meaning as given in the embodiment of (E4). 
     The intermediate compounds of formula (III) form a further aspect of the invention 
     
       
         
         
             
             
         
       
     
     wherein A 1 , A 2 , A 3 , A 4 , R 2  and Q 2  are as defined in relation to formula (I); or a salt thereof. The preferences for A 1 , A 2 , A 3 , A 4 , R 2  and Q 2  are the same as the preferences set out for the corresponding substituents of the compounds of formula (I). 
     The intermediate compounds of formula (IIIb) form a further aspect of the invention 
     
       
         
         
             
             
         
       
     
     wherein A 1 , A 2 , A 3 , A 4 , R 2  and Q 2  are as defined in relation to formula (I); or a salt thereof. The preferences for A 1 , A 2 , A 3 , A 4 , R 2  and Q 2  are the same as the preferences set out for the corresponding substituents of the compounds of formula (I). 
     In a preferred embodiment, the invention provides a compound of formula (III) wherein A 1 , A 2 , A 3  and A 4  are CH; R 2  is hydrogen; Q 2  is a moiety of formula (II); 
     In a further preferred embodiment, the invention provides a compound of formula (III) wherein A 1  is C—CN; A 2 , A 3 , and A 4  are CH; R 2  is hydrogen; Q 2  is a moiety of formula (II); 
     In a further preferred embodiment, the invention provides a compound of formula (III) wherein A 1  is C—F; A 2 , A 3 , and A 4  are CH; R 2  is hydrogen; Q 2  is a moiety of formula (II); 
     In a further preferred embodiment, the invention provides a compound of formula (III) wherein A 1  is C—Cl; A 2 , A 3 , and A 4  are CH; R 2  is hydrogen; Q 2  is a moiety of formula (II); 
     In a further preferred embodiment, the invention provides a compound of formula (III) wherein A 4  is C—F; A 2 , A 3 , and A 1  are CH; R 2  is hydrogen; Q 2  is a moiety of formula (II); 
     In a further preferred embodiment, the invention provides a compound of formula (III) wherein A 4  is C-OMe; A 2 , A 3 , and A 1  are CH; R 2  is hydrogen; Q 2  is a moiety of formula (II); 
     In a further preferred embodiment, the invention provides a compound of formula (III) wherein A 4  is N; A 2 , A 3 , and A 1  are CH; R 2  is hydrogen; Q 2  is a moiety of formula (II); 
     In a further preferred embodiment, the invention provides a compound of formula (III) wherein A 4  is N; A 1  is CN, A 2  and A 3  are CH; R 2  is hydrogen; Q 2  is a moiety of formula (II); 
     In a further preferred embodiment, the invention provides a compound of formula (III) wherein A 4  is N; A 1  is F, A 2  and A 3  are CH; R 2  is hydrogen; Q 2  is a moiety of formula (II); 
     In a further preferred embodiment, the invention provides a compound of formula (IIIb) wherein A 1  is C—CF 3 ; A 2 , A 3 , and A 4  are CH; R 2  is hydrogen; Q 2  is a moiety of formula (II); 
     In a preferred embodiment, the invention provides a compound of formula (Mb) wherein A 1 , A 2 , A 3  and A 4  are CH; R 2  is hydrogen; Q 2  is a moiety of formula (II); 
     In a further preferred embodiment, the invention provides a compound of formula (IIIb) wherein A 1  is C—CN; A 2 , A 3 , and A 4  are CH; R 2  is hydrogen; Q 2  is a moiety of formula (II); 
     In a further preferred embodiment, the invention provides a compound of formula (IIIb) wherein A 1  is C—F; A 2 , A 3 , and A 4  are CH; R 2  is hydrogen; Q 2  is a moiety of formula (II); 
     In a further preferred embodiment, the invention provides a compound of formula (IIIb) wherein A 1  is C—Cl; A 2 , A 3 , and A 4  are CH; R 2  is hydrogen; Q 2  is a moiety of formula (II); 
     In a further preferred embodiment, the invention provides a compound of formula (IIIb) wherein A 4  is C—F; A 2 , A 3 , and A 1  are CH; R 2  is hydrogen; Q 2  is a moiety of formula (II); 
     In a further preferred embodiment, the invention provides a compound of formula (IIIb) wherein A 4  is C-OMe; A 2 , A 3 , and A 1  are CH; R 2  is hydrogen; Q 2  is a moiety of formula (II); 
     In a further preferred embodiment, the invention provides a compound of formula (IIIb) wherein A 4  is N; A 2 , A 3 , and A 1  are CH; R 2  is hydrogen; Q 2  is a moiety of formula (II); 
     In a further preferred embodiment, the invention provides a compound of formula (IIIb) wherein A 4  is N; A 1  is CN, A 2  and A 3  are CH; R 2  is hydrogen; Q 2  is a moiety of formula (II); 
     In a further preferred embodiment, the invention provides a compound of formula (IIIb) wherein A 4  is N; A 1  is F, A 2  and A 3  are CH; R 2  is hydrogen; Q 2  is a moiety of formula (II); 
     In a further preferred embodiment, the invention provides a compound of formula (IIIb) wherein A 1  is C—CF3; A 2 , A 3 , and A 4  are CH; R 2  is hydrogen; Q 2  is a moiety of formula (II); 
     
       
         
           
               
             
               
                 TABLE 1 
               
             
            
               
                   
               
               
                 Table 1 provides 47 compounds of formula (Ia) according to  
               
               
                 formula (I) wherein A 1  is C—CN, A 2 , A 3  and A 4  are C—H and Q 2  is  
               
               
                 2-Methyl-5-pentafluoroethyl-4-trifluoromethyl-2H- 
               
               
                 pyrazol-3-yl, R 2  is H and Q 1  has the values listed in Table 1. 
               
            
           
           
               
               
            
               
                   
                 (Ia) 
               
               
                 
                   
                     
                     
                         
                         
                     
                   
                 
                   
               
               
                   
               
            
           
           
               
               
            
               
                 Compound 
                   
               
               
                 numbers 
                 Q 1   
               
               
                   
               
               
                 1.01 
                 5-bromo-furan-2-yl 
               
               
                 1.02 
                 2-bromo-phenyl 
               
               
                 1.03 
                 5-bromo-pyrid-3-yl 
               
               
                 1.04 
                 2-chloro-4-fluoro-phenyl 
               
               
                 1.05 
                 5-chloro-2-fluoro-phenyl 
               
               
                 1.06 
                 2-chloro-4-nitro-phenyl 
               
               
                 1.07 
                 2-chloro-5-nitro-phenyl 
               
               
                 1.08 
                 2-chloro-phenyl 
               
               
                 1.09 
                 3-chloro-phenyl 
               
               
                 1.10 
                 2-chloro-pyrid-3-yl 
               
               
                 1.11 
                 2-chloro-pyrid-4-yl 
               
               
                 1.12 
                 6-chloro-pyrid-3-yl 
               
               
                 1.13 
                 5-chloro-thiophen-2-yl 
               
               
                 1.14 
                 3-chloro-5-trifluoromethyl-pyrid-2-yl 
               
               
                 1.15 
                 4-cyano-phenyl 
               
               
                 1.16 
                 2,5-dichloro-phenyl 
               
               
                 1.17 
                 2,3-difluoro-phenyl 
               
               
                 1.18 
                 1,3-dimethyl-1H-pyrazol-5-yl 
               
               
                 1.19 
                 2-fluoro-phenyl 
               
               
                 1.20 
                 4-fluoro-phenyl 
               
               
                 1.21 
                 2-fluoro-pyrid-3-yl 
               
               
                 1.22 
                 2-fluoro-3-trifluoromethyl-phenyl 
               
               
                 1.23 
                 2-fluoro-5-trifluoromethyl-phenyl 
               
               
                 1.24 
                 4-fluoro-3-trifluoromethyl-phenyl 
               
               
                 1.25 
                 furan-2-yl 
               
               
                 1.26 
                 2-methoxy-phenyl 
               
               
                 1.27 
                 2-methyl-phenyl 
               
               
                 1.28 
                 3-methyl-pyrid-2-yl 
               
               
                 1.29 
                 4-methyl-1,2,3-thiadiazol-5-yl 
               
               
                 1.30 
                 2-methylthio-pyrid-3-yl 
               
               
                 1.31 
                 4-nitro-phenyl 
               
               
                 1.32 
                 phenyl 
               
               
                 1.33 
                 1,2,3-thiadiazol-4-yl 
               
               
                 1.34 
                 thiophen-2-yl 
               
               
                 1.35 
                 2-trifluoromethoxy-phenyl 
               
               
                 1.36 
                 4-trifluoromethoxy-phenyl 
               
               
                 1.37 
                 2-trifluoromethyl-phenyl 
               
               
                 1.38 
                 4-trifluoromethyl-phenyl 
               
               
                 1.39 
                 4-Pyridyl 
               
               
                 1.40 
                 2-chloro-4-cyano-phenyl 
               
               
                 1.41 
                 2,6-difluoro-4-cyano-phenyl 
               
               
                 1.42 
                 2,4,6-trifluoro-phenyl 
               
               
                 1.43 
                 2-methyl-4-cyano-phenyl 
               
               
                 1.44 
                 2-methyl-4-nitro-phenyl 
               
               
                 1.45 
                 2-methyl-4-fluoro-phenyl 
               
               
                 1.46 
                 Cyclopropyl 
               
               
                 1.47 
                 Benzyl 
               
               
                   
               
            
           
         
       
     
     Table 2: 
     Table 2 provides 47 compounds of formula (Ib) according to formula (I) wherein A 4  is C—F, A 1 , A 2  and A 3  are C—H and Q 2  is 2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl, R 2  is H and Q 1  has the values listed in Table 1. 
     Table 3: 
     Table 3 provides 47 compounds of formula (Ic) according to formula (I) wherein A 4  is C-OMe, A 1 , A 2  and A 3  are C—H and Q 2  is 2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl, R 2  is H and Q 1  has the values listed in Table 1. 
     Table 4: 
     Table 4 provides 47 compounds of formula (Id) according to formula (I) wherein A 1 , A 2 , A 3  and A 4  are C—H and Q 2  is 2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl, R 2  is H and Q 1  has the values listed in the table below. 
     Table 5: 
     Table 5 provides 47 compounds of formula (Ie) according to formula (I) wherein A 1  is C—Cl, A 2 , A 3  and A 4  are C—H and Q 2  is 2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl, R 2  is H and Q 1  has the values listed in Table 1. 
     Table 6: 
     Table 6 provides 47 compounds of formula (If) according to formula (I) wherein A 1  is C—F, A 2 , A 3  and A 4  are C—H and Q 2  is 2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl, R 2  is H and Q 1  has the values listed in Table 1. 
     Table 7: 
     Table 7 provides 47 compounds of formula (Ig) according to formula (I) wherein A 1  is C—CF 3 , A 2 , A 3  and A 4  are C—H and Q 2  is 2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl, R 2  is H and Q 1  has the values listed in Table 1. 
     Table 8: 
     Table 8 provides 47 compounds of formula (Ih) according to formula (I) wherein A 4  is N A 1 , A 2  and A 3  are C—H and Q 2  is 2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl, R 2  is H and Q 1  has the values listed in Table 1. 
     Table 9: 
     Table 9 provides 47 compounds of formula (II) according to formula (I) wherein A 4  is N, A 1  is CN, A 2  and A 3  are C—H and Q 2  is 2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl, R 2  is H and Q 1  has the values listed in Table 1. 
     Table 10: 
     Table 10 provides 47 compounds of formula (Ij) according to formula (I) wherein A 4  is N, A 1  is F, A 2  and A 3  are C—H and Q 2  is 2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl, R 2  is H and Q 1  has the values listed in Table 1. 
     
       
         
           
               
             
               
                 TABLE 11 
               
               
                   
               
             
            
               
                 Table 11 provides 9 compounds of formula (IIIb) wherein  
               
               
                 Q 2  is 2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H- 
               
               
                 pyrazol-3-yl, R 2  is H and A 1 , A 2 , A 3 , A 4  has the 
               
               
                 values listed in the table below. 
               
            
           
           
               
               
            
               
                   
                 (IIIb) 
               
               
                 
                   
                     
                     
                         
                         
                     
                   
                 
                   
               
               
                   
               
            
           
           
               
               
               
               
               
            
               
                 Compound 
                   
                   
                   
                   
               
               
                 number 
                 A 1   
                 A 2   
                 A 3   
                 A 4   
               
               
                   
               
               
                 11.01 
                 C—F 
                 C—H 
                 C—H 
                 C—H 
               
               
                 11.02 
                 C—CN 
                 C—H 
                 C—H 
                 C—H 
               
               
                 11.03 
                 C—H 
                 C—H 
                 C—H 
                 C—F 
               
               
                 11.04 
                 C—H 
                 C—H 
                 C—H 
                 C—OMe 
               
               
                 11.05 
                 C—H 
                 C—H 
                 C—H 
                 N 
               
               
                 11.06 
                 C—F 
                 C—H 
                 C—H 
                 N 
               
               
                 11.07 
                 C—CN 
                 C—H 
                 C—H 
                 N 
               
               
                 11.08 
                 C—CF3 
                 C—H 
                 C—H 
                 C—H 
               
               
                 11.09 
                 C—H 
                 C—H 
                 C—H 
                 C—H 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 12 
               
             
            
               
                   
               
               
                 Table 12 provides 9 compound of formula (III) wherein Q 2  is 
               
               
                 2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl, 
               
               
                 R 2  is H and A 1 , A 2 , A 3 , A 4  has the values listed in the table below. 
               
            
           
           
               
               
            
               
                   
                 (III) 
               
               
                 
                   
                     
                     
                         
                         
                     
                   
                 
                   
               
               
                   
               
            
           
           
               
               
               
               
               
            
               
                 Compound number 
                 A 1   
                 A 2   
                 A 3   
                 A 4   
               
               
                   
               
               
                 12.01 
                 C—F 
                 C—H 
                 C—H 
                 C—H 
               
               
                 12.02 
                 C—CN 
                 C—H 
                 C—H 
                 C—H 
               
               
                 12.03 
                 C—H 
                 C—H 
                 C—H 
                 C—F 
               
               
                 12.04 
                 C—H 
                 C—H 
                 C—H 
                 C—OMe 
               
               
                 12.05 
                 C—H 
                 C—H 
                 C—H 
                 N 
               
               
                 12.06 
                 C—F 
                 C—H 
                 C—H 
                 N 
               
               
                 12.07 
                 C—CN 
                 C—H 
                 C—H 
                 N 
               
               
                 12.08 
                 C—CF3 
                 C—H 
                 C—H 
                 C—H 
               
               
                 12.09 
                 C—H 
                 C—H 
                 C—H 
                 C—H 
               
               
                   
               
            
           
         
       
     
     The compounds of the invention may be made by the following methods. 
     (1) Compounds of formula (I), wherein G 1  is oxygen, may be prepared by reaction of a compound of formula (V) with an azido derivative, Q 2 -N 3 , in the presence of copper or a copper catalyst, such as copper sulfate or copper (I) iodide, and optionally in the presence of a base, such as N-ethyldiisopropylamine, in the presence of a solvent or a mixture of solvents, such as t-butanol, water. In the case of a Cu(II) catalyst, a reducing agent, such as sodium ascorbate may be used. In the case of a Cu(0) catalyst, such as an amine salt, an oxidising agent may be used. (See, for example: Angewandte Chemie, International Edition (2009), 48(27), 4900-4908 and cited references, Angew. Chem. Int. Ed. 2008, 47, 2182-2184 and cited references, and Eur. J. Org. Chem. 2006, 51-68 and cited references). 
     
       
         
         
             
             
         
       
     
     (2) Compounds of formula (V), wherein G 1  is oxygen may be prepared by acylation of a compound of formula (VI) with a compound of formula (IV), wherein R is OH, in the presence of a coupling reagent, such as DCC (N,N′-dicyclohexylcarbodiimide), EDC (1-ethyl-3-[3-dimethylamino-propyl]carbodiimide hydrochloride) or BOP-Cl (bis(2-oxo-3-oxazolidinyl)phosphonic chloride), in the presence of a base, such as pyridine, triethylamine, 4-(dimethylamino)pyridine or diisopropylethylamine, and optionally in the presence of a nucleophilic catalyst, such as hydroxybenzotriazole. Optionally, when R is Cl, the acylation reaction may be carried out under basic conditions (for example in the presence of pyridine, triethylamine, 4-(dimethylamino)pyridine or diisopropylethylamine), optionally in the presence of a nucleophilic catalyst. Alternatively, the reaction may be conducted in a biphasic system comprising an organic solvent, preferably ethyl acetate, and an aqueous solvent, preferably a solution of sodium bicarbonate. Optionally, when R is C 1 -C 6 alkoxy, the amide may be prepared by heating the ester (IV) and amine (VI) together. 
     (3) Compounds of formula (VI), wherein R 1  is C 1 -C 6 alkyl, may be prepared from a compound of formula (VI) wherein R 1  is H via reductive amination by reaction of the amine with an aldehyde or ketone and a reducing agent such as sodium cyanoborohydride. Alternatively alkylation may be achieved by treating the amine with an alkylating agent such as an alkyl halide, optionally in the presence of a base. 
     (4) Compounds of formula (I), wherein G 1  is oxygen, may be also be prepared by reaction of a compound of formula (III) with a compound of formula (IV) as described in (2). 
     
       
         
         
             
             
         
       
     
     (5) Compounds of formula (III) may be prepared from a compound of formula (VI) using the same conditions as described in (1). 
     (6) Compounds of formula (VI), wherein R 1  is H may be prepared by the reduction of a nitro compound of formula (VIII) by, for example, treatment with tin chloride under acidic conditions, or hydrogenation catalysed by a metal such as iron. 
     
       
         
         
             
             
         
       
     
     (7) Compounds of formula (III), wherein R 1  is H, may be prepared by the reduction of a nitro compound of formula (IIIb) by the method described in (6). 
     
       
         
         
             
             
         
       
     
     (8) Compounds of formula (IIIb) may be prepared from a compound of formula (VIII) by reaction with an azido derivative, Q 2 -N 3 , using the same conditions as described in (1). 
     (9) Compounds of formula (I), wherein G 1  is sulfur, may be prepared from a compound of formula (I), wherein G 1  is oxygen, by treatment with a thio-transfer reagent, such as Lawesson&#39;s reagent or phosphorus pentasulfide. 
     (10) Compounds of formula (III), may be prepared from a compound of formula (VI), wherein P is a suitable protecting group, using the same conditions as described in (1), followed by removal of the protecting group P under standard conditions. 
     
       
         
         
             
             
         
       
     
     (11) Compounds of formula (VIII) may be prepared from a compound of formula (IX), wherein A 1 , A 2 , A 3  and A 4  are each independentely C-LG or C—H, and LG is a leaving group, such as fluorine or chlorine, by reaction with a nucleophile, such as an aliphatic alcohol, sodium cyanide. 
     
       
         
         
             
             
         
       
     
     (12) Compounds of formula (IIIb), wherein A 1 , A 2 , A 3  and A 4  are as described for the compound of formula (I) may be prepared from a compound of formula (IIIb), wherein A 1 , A 2 , A 3  and A 4  are each independentely C-LG or C—H, and LG is a leaving group, such as fluorine or chlorine, by reaction with a nucleophile, such as an aliphatic alcohol, sodium cyanide. 
     
       
         
         
             
             
         
       
     
     14) Compounds of formula (VII), wherein Q 2  is as described for the compound of formula (I), may be also be prepared by reaction of a compound of formula (II) with sodium nitrite followed by addition of sodium azide. See, for example: Diazo Chemistry I: Aromatic and Heteroaromatic Compounds. Zollinger, H. Germany. (1994), 380 pp. Publisher: (VCH, Weinheim, Germany) and cited references. 
     
       
         
         
             
             
         
       
     
     15) Compounds of formula (II) wherein R5 is methyl, R7 is perfluoroethyl and R 6  is trifluoromethyl, can be made from a compound of formula (IIa) wherein LG is halogen, such as fluoride or chloride, by reaction with a azide salt such as sodium azide. 
     
       
         
         
             
             
         
       
     
     16) Alternatively, compounds of formula (NH2Q2) are either known or may be made by methods known to a person skilled in the art. 
     17) Compounds of formula (VIII) or (VI) are either known or may be made by methods known to a person skilled in the art. 
     The compounds of formula (I) can be used to combat and control infestations of insect pests such as Lepidoptera, Diptera, Hemiptera, Thysanoptera, Orthoptera, Dictyoptera, Coleoptera, Siphonaptera, Hymenoptera and Isoptera and also other invertebrate pests, for example, acarine, nematode and mollusc pests. Insects, acarines, nematodes and molluscs are hereinafter collectively referred to as pests. The pests which may be combated and controlled by the use of the invention compounds include those pests associated with agriculture (which term includes the growing of crops for food and fibre products), horticulture and animal husbandry, companion animals, forestry and the storage of products of vegetable origin (such as fruit, grain and timber); those pests associated with the damage of man-made structures and the transmission of diseases of man and animals; and also nuisance pests (such as flies). 
     Examples of pest species which may be controlled by the compounds of formula (I) include:  Myzus persicae  (aphid),  Aphis gossypii  (aphid),  Aphis fabae  (aphid),  Lygus  spp. (capsids),  Dysdercus  spp. (capsids),  Nilaparvata lugens  (planthopper),  Nephotettixc incticeps  (leafhopper),  Nezara  spp. (stinkbugs),  Euschistus  spp. (stinkbugs),  Leptocorisa  spp. (stinkbugs),  Frankliniella occidentalis  (thrip),  Thrips  spp. (thrips),  Leptinotarsa decemlineata  (Colorado potato beetle),  Anthonomus grandis  (boll weevil),  Aonidiella  spp. (scale insects),  Trialeurodes  spp. (white flies),  Bemisia tabaci  (white fly),  Ostrinia nubilalis  (European corn borer),  Spodoptera littoralis  (cotton leafworm),  Heliothis virescens  (tobacco budworm),  Helicoverpa armigera  (cotton bollworm),  Helicoverpa zea  (cotton bollworm),  Sylepta derogata  (cotton leaf roller),  Pieris brassicae  (white butterfly),  Plutella xylostella  (diamond back moth),  Agrotis  spp. (cutworms),  Chilo suppressalis  (rice stem borer),  Locusta migratoria  (locust),  Chortiocetes terminifera  (locust),  Diabrotica  spp. (rootworms),  Panonychus ulmi  (European red mite),  Panonychus citri  (citrus red mite),  Tetranychus urticae  (two-spotted spider mite),  Tetranychus cinnabarinus  (carmine spider mite),  Phyllocoptruta oleivora  (citrus rust mite),  Polyphagotarsonemus latus  (broad mite),  Brevipalpus  spp. (flat mites),  Boophilus microplus  (cattle tick),  Dermacentor variabilis  (American dog tick),  Ctenocephalides felis  (cat flea),  Liriomyza  spp. (leafminer),  Musca domestica  (housefly),  Aedes aegypti  (mosquito),  Anopheles  spp. (mosquitoes),  Culex  spp. (mosquitoes),  Lucillia  spp. (blowflies),  Blattella germanica  (cockroach),  Periplaneta americana  (cockroach),  Blatta orientalis  (cockroach), termites of the  Mastotermitidae  (for example  Mastotermes  spp.), the  Kalotermitidae  (for example  Neotermes  spp.), the  Rhinotermitidae  (for example  Coptotermes formosanus, Reticulitermes flavipes, R. speratu, R. virginicus, R. hesperus , and  R. santonensis ) and the  Termitidae  (for example  Globitermes  sulfureus),  Solenopsis geminata  (fire ant),  Monomorium pharaonis  (pharaoh&#39;s ant),  Damalinia  spp. and  Linognathus  spp. (biting and sucking lice),  Meloidogyne  spp. (root knot nematodes),  Globodera  spp. and  Heterodera  spp. (cyst nematodes),  Pratylenchus  spp. (lesion nematodes),  Rhodopholus  spp. (banana burrowing nematodes),  Tylenchulus  spp. (citrus nematodes),  Haemonchus contortus  (barber pole worm),  Caenorhabditis elegans  (vinegar eelworm),  Trichostrongylus  spp. (gastro intestinal nematodes) and  Deroceras reticulatum  (slug). 
     The invention therefore provides a method of combating and controlling insects, acarines, nematodes or molluscs which comprises applying an insecticidally, acaricidally, nematicidally or molluscicidally effective amount of a compound of formula (I), or a composition containing a compound of formula (I), to a pest, a locus of pest, preferably a plant, or to a plant susceptible to attack by a pest or a plant propagation material. The compounds of formula (I) are preferably used against insects, acarines or nematodes. 
     As for acari, for example,  Tetranychus cinnabarinus, Tetranychus urticae, Panonychus citri, Aculops pelekassi, Tarsonemus  spp. 
     As for nematodes, for example,  Meloidogyne incognita, Bursaphelenchus lignicolus Mamiya et Kiyohara, Aphelenchoides besseyi, Heterodera glycines, Pratylenchus  spp. 
     Additionally, the compounds can be used for controlling animal pests, in particular insects, arachnids, helminths, nematodes and molluscs, which are encountered in agriculture, in horticulture, the field of veterinary medicine, in forests, in gardens and leisure facilities, in the protection of stored products and of materials, and in the hygiene sector. They may preferably be employed as plant protection agents. They may be active against normally sensitive and resistant species and against all or some stages of development. 
     These pests include inter alia: 
     From the order of the Anoplura (Phthiraptera), for example,  Damalinia  spp.,  Haematopinus  spp.,  Linognathus  spp.,  Pediculus  spp.,  Trichodectes  spp. 
     From the class of the Arachnida, for example,  Acarus siro, Aceria sheldoni, Aculops  spp.,  Aculus  spp.,  Amblyomma  spp.,  Argas  spp.,  Boophilus  spp.,  Brevipalpus  spp.,  Bryobia praetiosa, Chorioptes  spp.,  Dermanyssus gallinae, Eotetranychus  spp.,  Epitrimerus pyri, Eutetranychus  spp.,  Eriophyes  spp.,  Hemitarsonemus  spp.,  Hyalomma  spp.,  Ixodes  spp., to  Latrodectus mactans, Metatetranychus  spp.,  Oligonychus  spp.,  Ornithodoros  spp.,  Panonychus  spp.,  Phyllocoptruta oleivora, Polyphagotarsonemus latus, Psoroptes  spp.,  Rhipicephalus  spp.,  Rhizoglyphus  spp.,  Sarcoptes  spp.,  Scorpio maurus, Stenotarsonemus  spp.,  Tarsonemus  spp.,  Tetranychus  spp.,  Vasates lycopersici.    
     From the class of the Bivalva, for example,  Dreissena  spp. 
     From the order of the Chilopoda, for example,  Geophilus  spp.,  Scutigera  spp. 
     From the order of the Coleoptera, for example,  Acanthoscehdes obtectus, Adoretus  spp.,  Agelastica alni, Agriotes  spp.,  Amphimallon solstitialis, Anobium punctatum, Anoplophora  spp.,  Anthonomus  spp.,  Anthrenus  spp.,  Apogonia  spp.,  Atomaria  spp.,  Attagenus  spp.,  Bruchidius obtectus, Bruchus  spp.,  Ceuthorhynchus  spp.,  Cleonus mendicus, Conoderus  spp.,  Cosmopolites  spp.,  Costelytra zealandica, Curculio  spp.,  Cryptorhynchus lapathi, Dermestes  spp.,  Diabrotica  spp.,  Epilachna  spp.,  Faustinus cubae, Gibbium psylloides, Heteronychus arator, Hylamorpha elegans, Hylotrupes bajulus, Hypera postica, Hypothenemus  spp.,  Lachnosterna consanguinea, Leptinotarsa decemlineata, Lissorhoptrus oryzophilus, Lixus  spp.,  Lyctus  spp.,  Meligethes aeneus, Melolontha melolontha, Migdolus  spp.,  Monochamus  spp.,  Naupactus xanthographus, Niptus hololeucus, Oryctes rhinoceros, Oryzaephilus surinamensis, Otiorrhynchus sulcatus, Oxycetonia jucunda, Phaedon cochleariae, Phyllophaga  spp.,  Popillia japonica, Premnotrypes  spp.,  Psylliodes chrysocephala, Ptinus  spp.,  Rhizobius ventralis, Rhizopertha dominica, Sitophilus  spp.,  Sphenophorus  spp.,  Sternechus  spp.,  Symphyletes  spp.,  Tenebrio molitor, Tribolium  spp.,  Trogoderma  spp.,  Tychius  spp.,  Xylotrechus  spp.,  Zabrus  spp. 
     From the order of the Collembola, for example,  Onychiurus armatus.    
     From the order of the Dermaptera, for example,  Forficula auricularia.    
     From the order of the Diplopoda, for example,  Blaniulus guttulatus.    
     From the order of the Diptera, for example,  Aedes  spp.,  Anopheles  spp.,  Bibio hortulanus, Calliphora erythrocephala, Ceratitis capitata, Chrysomyia  spp.,  Cochliomyia  spp.,  Cordylobia anthropophaga, Culex  spp.,  Cuterebra  spp.,  Dacus oleae, Dermatobia hominis, Drosophila  spp.,  Fannia  spp.,  Gastrophilus  spp.,  Hylemyia  spp.,  Hyppobosca  spp.,  Hypoderma  spp.,  Liriomyza  spp.,  Lucilia  spp.,  Musca  spp.,  Nezara  spp.,  Oestrus  spp.,  Oscinella frit, Pegomyia hyoscyami, Phorbia  spp.,  Stomoxys  spp.,  Tabanus  spp.,  Tannia  spp.,  Tipula paludosa, Wohlfahrtia  spp. 
     From the class of the Gastropoda, for example,  Arion  spp.,  Biomphalaria  spp.,  Bulinus  spp.,  Deroceras  spp.,  Galba  spp.,  Lymnaea  spp.,  Oncomelania  spp.,  Succinea  spp. 
     From the class of the helminths, for example,  Ancylostoma duodenale, Ancylostoma ceylanicum, Acylostoma braziliensis, Ancylostoma  spp.,  Ascaris lubricoides, Ascaris  spp.,  Brugia malayi, Brugia timori, Bunostomum  spp.,  Chabertia  spp.,  Clonorchis  spp.,  Cooperia  spp.,  Dicrocoelium  spp,  Dictyocaulus filaria, Diphyllobothrium latum, Dracunculus medinensis, Echinococcus granulosus, Echinococcus multilocularis, Enterobius vermicularis, Faciola  spp.,  Haemonchus  spp.,  Heterakis  spp.,  Hymenolepis nana, Hyostrongulus  spp.,  Loa Loa, Nematodirus  spp.,  Oesophagostomum  spp.,  Opisthorchis  spp.,  Onchocerca volvulus, Ostertagia  spp.,  Paragonimus  spp.,  Schistosomen  spp.,  Strongyloides fuelleborni, Strongyloides stercoralis, Stronyloides  spp.,  Taenia saginata, Taenia solium, Trichinella spiralis, Trichinella nativa, Trichinella britovi, Trichinella nelsoni, Trichinella pseudopsiralis, Trichostrongulus  spp.,  Trichuris trichuria, Wuchereria bancrofti.    
     It may be furthermore possible to control protozoa, such as Eimeria. 
     From the order of the Heteroptera, for example,  Anasa tristis, Antestiopsis  spp.,  Blissus  spp.,  Calocoris  spp.,  Campylomma livida, Cavelerius  spp.,  Cimex  spp.,  Creontiades dilutus, Dasynus piperis, Dichelops furcatus, Diconocoris hewetti, Dysdercus  spp.,  Euschistus  spp.,  Eurygaster  spp.,  Heliopeltis  spp.,  Horcias nobilellus, Leptocorisa  spp.,  Leptoglossus phyllopus, Lygus  spp.,  Macropes excavatus, Miridae, Nezara  spp.,  Oebalus  spp.,  Pentomidae, Piesma quadrata, Piezodorus  spp.,  Psallus seriatus, Pseudacysta persea, Rhodnius  spp.,  Sahlbergella singularis, Scotinophora  spp.,  Stephanitis nashi, Tibraca  spp.,  Triatoma  spp. 
     From the order of the Homoptera, for example,  Acyrthosipon  spp.,  Aeneolamia  spp.,  Agonoscena  spp.,  Aleurodes  spp.,  Aleurolobus barodensis, Aleurothrixus  spp.,  Amrasca  spp.,  Anuraphis cardui, Aonidiella  spp.,  Aphanostigma piri, Aphis  spp.,  Arboridia apicalis, Aspidiella  spp.,  Aspidiotus  spp.,  Atanus  spp.,  Aulacorthum solani, Bemisia  spp.,  Brachycaudus helichrysii, Brachycolus  spp.,  Brevicoryne brassicae, Calligypona marginata, Carneocephala fulgida, Ceratovacuna lanigera, Cercopidae, Ceroplastes  spp.,  Chaetosiphon fragaefolii, Chionaspis tegalensis, Chlorita onukii, Chromaphis juglandicola, Chrysomphalus ficus, Cicadulina mbila, Coccomytilus halli, Coccus  spp.,  Cryptomyzus ribis, Dalbulus  spp.,  Dialeurodes  spp.,  Diaphorina  spp.,  Diaspis  spp.,  Doralis  spp.,  Drosicha  spp.,  Dysaphis  spp.,  Dysmicoccus  spp.,  Empoasca  spp.,  Eriosoma  spp.,  Erythroneura  spp.,  Euscelis bilobatus, Geococcus coffeae, Homalodisca coagulata, Hyalopterus arundinis, Icerya  spp.,  Idiocerus  spp.,  Idioscopus  spp.,  Laodelphax striatellus, Lecanium  spp.,  Lepidosaphes  spp.,  Lipaphis erysimi, Macrosiphum  spp.,  Mahanarva fimbriolata, Melanaphis sacchari, Metcalfiella  spp.,  Metopolophium dirhodum, Monellia costalis, Monelliopsis pecanis, Myzus  spp.,  Nasonovia ribisnigri, Nephotettix  spp.,  Nilaparvata lugens, Oncometopia  spp.,  Orthezia praelonga, Parabemisia myricae, Paratrioza  spp.,  Parlatoria  spp.,  Pemphigus  spp.,  Peregrinus maidis, Phenacoccus  spp.,  Phloeomyzus passerinii, Phorodon humuli, Phylloxera  spp.,  Pinnaspis aspidistrae, Planococcus  spp.,  Protopulvinaria pyriformis, Pseudaulacaspis pentagona, Pseudococcus  spp.,  Psylla  spp.,  Pteromalus  spp.,  Pyrilla  spp.,  Quadraspidiotus  spp.,  Quesada gigas, Rastrococcus  spp.,  Rhopalosiphum  spp.,  Saissetia  spp.,  Scaphoides titanus, Schizaphis graminum, Selenaspidus articulatus, Sogata  spp.,  Sogatella furcifera, Sogatodes  spp.,  Stictocephala festina, Tenalaphara malayensis, Tinocallis caryaefoliae, Tomaspis  spp.,  Toxoptera  spp.,  Trialeurodes vaporariorum, Trioza  spp.,  Typhlocyba  spp.,  Unaspis  spp.,  Viteus vitifolii.    
     From the order of the Hymenoptera, for example,  Diprion  spp.,  Hoplocampa  spp.,  Lasius  spp.,  Mono - morium pharaonis, Vespa  spp. 
     From the order of the Isopoda, for example,  Armadillidium vulgare, Oniscus asellus, Porcellio scaber.    
     From the order of the Isoptera, for example,  Reticulitermes  spp.,  Odontotermes  spp. 
     From the order of the Lepidoptera, for example,  Acronicta major, Aedia leucomelas, Agrotis  spp.,  Alabama argillacea, Anticarsia  spp.,  Barathra brassicae, Bucculatrix thurberiella, Bupalus piniarius, Cacoecia podana, Capua reticulana, Carpocapsa pomonella, Chematobia brumata, Chilo  spp.,  Choristoneura fumiferana, Clysia ambiguella, Cnaphalocerus  spp.,  Earias insulana, Ephestia kuehniella, Euproctis chrysorrhoea, Euxoa  spp.,  Feltia  spp.,  Galleria mellonella, Helicoverpa  spp.,  Heliothis  spp.,  Hofmannophila pseudospretella, Homona magnanima, Hyponomeuta padella, Laphygma  spp.,  Lithocolletis blancardella, Lithophane antennata, Loxagrotis albicosta, Lymantria  spp.,  Malacosoma neustria, Mamestra brassicae, Mocis repanda, Mythimna separata, Oria  spp.,  Oulema oryzae, Panolis flammea, Pectinophora gossypiella, Phyllocnistis citrella, Pieris  spp.,  Plutella xylostella, Prodenia  spp.,  Pseudaletia  spp.,  Pseudoplusia includens, Pyrausta nubilalis, Spodoptera  spp.,  Thermesia gemmatalis, Tinea pellionella, Tineola bisselliella, Tortrix viridana, Trichoplusia  spp. 
     From the order of the Orthoptera, for example,  Acheta domesticus, Blatta orientalis, Blattella germanica, Gryllotalpa  spp.,  Leucophaea maderae, Locusta  spp.,  Melanoplus  spp.,  Periplaneta americana, Schistocerca gregaria.    
     From the order of the Siphonaptera, for example,  Ceratophyllus  spp.,  Xenopsylla cheopis.    
     From the order of the Symphyla, for example,  Scutigerella immaculata.    
     From the order of the Thysanoptera, for example,  Baliothrips biformis, Enneothrips flavens, Frankliniella  spp.,  Heliothrips  spp.,  Hercinothrips femoralis, Kakothrips  spp.,  Rhipiphorothrips cruentatus, Scirtothrips  spp.,  Taeniothrips cardamoni, Thrips  spp. 
     From the order of the Thysanura, for example,  Lepisma saccharina.    
     The phytoparasitic nematodes include, for example,  Anguina  spp.,  Aphelenchoides  spp.,  Belonoaimus  spp.,  Bursaphelenchus  spp.,  Ditylenchus dipsaci, Globodera  spp.,  Heliocotylenchus  spp.,  Heterodera  spp.,  Longidorus  spp.,  Meloidogyne  spp.,  Pratylenchus  spp.,  Radopholus similis, Rotylenchus  spp.,  Trichodorus  spp.,  Tylenchorhynchus  spp.,  Tylenchulus  spp.,  Tylenchulus semipenetrans, Xiphinema  spp. 
     Furthermore, in the field of veterinary medicine, the novel compounds of the present invention can be effectively used against various harmful animal parasitic pests (endoparasites and ectoparasites), for example, insects and helminthes. 
     Examples of such animal parasitic pests include the pests as described below. 
     Examples of the insects include  Gasterophilus  spp.,  Stomoxys  spp.,  Trichodectes  spp.,  Rhodnius  spp.,  Ctenocephalides canis, Cimx lecturius, Ctenocephalides felis, Lucilia cuprina , and the like. 
     Examples of acari include  Ornithodoros  spp.,  Ixodes  spp.,  Boophilus  spp., and the like. 
     In the veterinary fields, e.g. in the field of veterinary medicine, the active compounds according to the present invention are active against animal parasites, in particular ectoparasites or endoparasites. 
     The term endoparasites includes in particular helminths, such as cestodes, nematodes or trematodes, and protozoae, such as coccidia. 
     Ectoparasites are typically and preferably arthropods, in particular insects such as flies (stinging and licking), parasitic fly larvae, lice, hair lice, bird lice, fleas and the like; or acarids, such as ticks, for examples hard ticks or soft ticks, or mites, such as scab mites, harvest mites, bird mites and the like. 
     These parasites include: 
     From the order of the Anoplurida, for example  Haematopinus  spp.,  Linognathus  spp.,  Pediculus  spp.,  Phtirus  spp.,  Solenopotes  spp.; particular examples are:  Linognathus setosus, Linognathus vituli, Linognathus ovillus, Linognathus oviformis, Linognathus pedalis, Linognathus stenopsis, Haematopinus asini macrocephalus, Haematopinus eurysternus, Haematopinus suis, Pediculus humanus capitis, Pediculus humanus corporis, Phylloera vastatrix, Phthirus pubis, Solenopotes capillatus ; from the order of the Mallophagida and the suborders Amblycerina and Ischnocerina, for example  Trimenopon  spp.,  Menopon  spp.,  Trinoton  spp.,  Bovicola  spp.,  Werneckiella  spp.,  Lepikentron  spp.,  Damalina  spp.,  Trichodectes  spp.,  Felicola  spp.; particular examples are:  Bovicola bovis, Bovicola ovis, Bovicola limbata, Damalina bovis, Trichodectes canis, Felicola subrostratus, Bovicola caprae, Lepikentron ovis, Werneckiella equi ; from the order of the Diptera and the suborders Nematocerina and Brachycerina, for example  Aedes  spp.,  Anopheles  spp.,  Culex  spp.,  Simulium  spp.,  Eusimulium  spp.,  Phlebotomus  spp.,  Lutzomyia  spp.,  Culicoides  spp.,  Chrysops  spp.,  Odagmia  spp.,  Wilhelmia  spp.,  Hybomitra  spp.,  Atylotus  spp.,  Tabanus  spp.,  Haematopota  spp.,  Philipomyia  spp.,  Braula  spp.,  Musca  spp.,  Hydrotaea  spp.,  Stomoxys  spp.,  Haematobia  spp.,  Morellia  spp.,  Fannia  spp.,  Glossina  spp.,  Calliphora  spp.,  Lucilia  spp.,  Chrysomyia  spp.,  Wohlfahrtia  spp.,  Sarcophaga  spp.,  Oestrus  spp.,  Hypoderma  spp.,  Gasterophilus  spp.,  Hippobosca  spp.,  Lipoptena  spp.,  Melophagus  spp.,  Rhinoestrus  spp.,  Tipula  spp.; particular examples are:  Aedes aegypti, Stegomyia albopicta  ( Aedes albopictus ),  Aedes taeniorhynchus, Anopheles gambiae, Anopheles maculipennis, Calliphora erythrocephala, Chrysozona pluvialis, Culex quinquefasciatus, Culex pipiens, Culex tarsalis, Fannia canicularis, Sarcophaga carnaria, Stomoxys calcitrans, Tipula paludosa, Lucilia cuprina, Lucilia sericata, Simulium reptans, Phlebotomus papatasi, Phlebotomus longipalpis, Odagmia ornata, Wilhelmia equina, Boophthora erythrocephala, Tabanus bromius, Tabanus spodopterus, Tabanus atratus, Tabanus sudeticus, Hybomitra ciurea, Chrysops caecutiens, Chrysops relictus, Haematopota pluvialis, Haematopota italica, Musca autumnalis, Musca domestica, Haematobia irritans irritans, Haematobia irritans exigua, Haematobia stimulans, Hydrotaea irritans, Hydrotaea albipuncta, Chrysomya chloropyga, Chrysomya bezziana, Oestrus ovis, Hypoderma bovis, Hypoderma lineatum, Przhevalskiana silenus, Dermatobia hominis, Melophagus ovinus, Lipoptena capreoli, Lipoptena cervi, Hippobosca variegata, Hippobosca equina, Gasterophilus intestinalis, Gasterophilus haemorroidalis, Gasterophilus inermis, Gasterophilus nasalis, Gasterophilus nigricornis, Gasterophilus pecorum, Braula coeca ; from the order of the Siphonapterida, for example  Pulex  spp.,  Ctenocephalides  spp.,  Tunga  spp.,  Xenopsylla  spp.,  Ceratophyllus  spp.; particular examples are:  Ctenocephalides canis, Ctenocephalides felis, Pulex irritans, Tunga penetrans, Xenopsylla cheopis ; from the order of the Heteropterida, for example  Cimex  spp.,  Triatoma  spp.,  Rhodnius  spp.,  Panstrongylus  spp. 
     From the order of the Blattarida, for example  Blatta orientalis, Periplaneta americana, Blattela germanica, Supella  spp. (e.g.  Suppella longipalpa ); 
     From the subclass of the Acari (Acarina) and the orders of the Meta- and Mesostigmata, for example  Argas  spp.,  Ornithodorus  spp.,  Otobius  spp.,  Ixodes  spp.,  Amblyomma  spp.,  Rhipicephalus  ( Boophilus ) spp.,  Dermacentor  spp.,  Haemophysalis  spp.,  Hyalomma  spp.,  Dermanyssus  spp.,  Rhipicephalus  spp. (the original genus of multi host ticks),  Ornithonyssus  spp.,  Pneumonyssus  spp.,  Raillietia  spp.,  Pneumonyssus  spp.,  Sternostoma  spp.,  Varroa  spp.,  Acarapis  spp.; particular examples are:  Argas persicus, Argas reflexus, Ornithodorus moubata, Otobius megnini, Rhipicephalus  ( Boophilus )  microplus, Rhipicephalus  ( Boophilus )  decoloratus, Rhipicephalus  ( Boophilus )  annulatus, Rhipicephalus  ( Boophilus )  calceratus, Hyalomma anatolicum, Hyalomma aegypticum, Hyalomma marginatum, Hyalomma transiens, Rhipicephalus evertsi, Ixodes ricinus, Ixodes hexagonus, Ixodes canisuga, Ixodes pilosus, Ixodes rubicundus, Ixodes scapularis, Ixodes holocyclus, Haemaphysalis concinna, Haemaphysalis punctata, Haemaphysalis cinnabarina, Haemaphysalis otophila, Haemaphysalis leachi, Haemaphysalis longicorni, Dermacentor marginatus, Dermacentor reticulatus, Dermacentor pictus, Dermacentor albipictus, Dermacentor andersoni, Dermacentor variabilis, Hyalomma mauritanicum, Rhipicephalus sanguineus, Rhipicephalus bursa, Rhipicephalus appendiculatus, Rhipicephalus capensis, Rhipicephalus turanicus, Rhipicephalus zambeziensis, Amblyomma americanum, Amblyomma variegatum, Amblyomma maculatum, Amblyomma hebraeum, Amblyomma cajennense, Dermanyssus gallinae, Ornithonyssus bursa, Ornithonyssus sylviarum, Varroa jacobsoni ; from the order of the Actinedida (Prostigmata) and Acaridida (Astigmata), for example  Acarapis  spp.,  Cheyletiella  spp.,  Ornithocheyletia  spp.,  Myobia  spp.,  Psorergates  spp.,  Demodex  spp.,  Trombicula  spp.,  Listrophorus  spp.,  Acarus  spp.,  Tyrophagus  spp.,  Caloglyphus  spp.,  Hypodectes  spp.,  Pterolichus  spp.,  Psoroptes  spp.,  Chorioptes  spp.,  Otodectes  spp.,  Sarcoptes  spp.,  Notoedres  spp.,  Knemidocoptes  spp.,  Cytodites  spp.,  Laminosioptes  spp.; particular examples are:  Cheyletiella yasguri, Cheyletiella blakei, Demodex canis, Demodex bovis, Demodex ovis, Demodex caprae, Demodex equi, Demodex caballi, Demodex suis, Neotrombicula autumnalis, Neotrombicula desaleri, Neoschongastia xerothermobia, Trombicula akamushi, Otodectes cynotis, Notoedres cati, Sarcoptis canis, Sarcoptes bovis, Sarcoptes ovis, Sarcoptes rupicaprae  ( S. caprae ),  Sarcoptes equi, Sarcoptes suis, Psoroptes ovis, Psoroptes cuniculi, Psoroptes equi, Chorioptes bovis, Psoergates ovis, Pneumonyssoidic mange, Pneumonyssoides caninum, Acarapis woodi.    
     The active compounds according to the invention are also suitable for controlling arthropods, helminths and protozoae, which attack animals. 
     Animals include agricultural livestock such as, for example, cattle, sheep, goats, horses, pigs, donkeys, camels, buffaloes, rabbits, chickens, turkeys, ducks, geese, cultured fish, honeybees. 
     Moreover, animals include domestic animals—also referred to as companion animals—such as, for example, dogs, cats, cage birds, aquarium fish and what are known as experimental animals such as, for example, hamsters, guinea pigs, rats and mice. 
     By controlling these arthropods, helminths and/or protozoae, it is intended to reduce deaths and improve performance (in the case of meat, milk, wool, hides, eggs, honey and the like) and health of the host animal, so that more economical and simpler animal keeping is made possible by the use of the active compounds according to the invention. 
     For example, it may be desirable to prevent or interrupt the uptake of blood by the parasites from the hosts. 
     Also, controlling the parasites may help to prevent the transmittance of infectious agents. 
     The term “controlling” as used herein with regard to the veterinary field, means that the active compounds are effective in reducing the incidence of the respective parasite in an animal infected with such parasites to innocuous levels. 
     More specifically, “controlling”, as used herein, means that the active compound is effective in killing the respective parasite, inhibiting its growth, or inhibiting its proliferation. Generally, when used for the treatment of animals the active compounds according to the invention can be applied directly. 
     Preferably they are applied as pharmaceutical compositions which may contain pharmaceutically acceptable excipients and/or auxiliaries which are known in the art. 
     In the veterinary field and in animal keeping, the active compounds are applied (e.g. administered) in the known manner by enteral administration in the form of, for example, tablets, capsules, drinks, drenches, granules, pastes, boluses, the feed-through method, suppositories; by parenteral administration, such as, for example, by injections 
     (intramuscular, subcutaneous, intravenous, intraperitoneal and the like), implants, by nasal application, by dermal application in the form of, for example, bathing or dipping, spraying, pouring-on and spotting-on, washing, dusting, and with the aid of active-compound-comprising shaped articles such as collars, ear tags, tail tags, limb bands, halters, marking devices and the like. 
     The active compounds may be formulated as shampoo or as suitable formulations usable in aerosols, unpressurized sprays, for example pump sprays and atomizer sprays. 
     When used for livestock, poultry, domestic animals and the like, the active compounds according to the invention can be applied as formulations (for example powders, wettable powders [“WP”], emulsions, emulsifiable concentrates [“EC”], flowables, homogeneous solutions, and suspension concentrates [“SC”]) which comprise the active compounds in an amount of from 1 to 80 percent by weight, either directly or after dilution (e.g. 100- to 10 000-fold dilution), or else as a chemical bath. 
     When used in the veterinary field the active compounds according to the invention may be used in combination with suitable synergists or other active compounds, such as for example, acaricides, insecticides, anthelmintics, anti-protozoal drugs. 
     In the present invention, a substance having an insecticidal action against pests including all of these is referred to as an insecticide. 
     An active compound of the present invention can be prepared in conventional formulation forms, when used as an insecticide. 
     Examples of the formulation forms include solutions, emulsions, wettable powders, water dispersible granules, suspensions, powders, foams, pastes, tablets, granules, aerosols, active compound-infiltrated natural and synthetic materials, microcapsules, seed coating agents, formulations used with a combustion apparatus (for example, fumigation and smoking cartridges, cans, coils or the like as the combustion apparatus), ULV (cold mist, warm mist), and the like. 
     These formulations can be produced by methods that are known per se. 
     For example, a formulation can be produced by mixing the active compound with a developer, that is, a liquid diluent or carrier; a liquefied gas diluent or carrier; a solid diluent or carrier, and optionally with a surfactant, that is, an emulsifier and/or dispersant and/or foaming agent. 
     In the case where water is used as the developer, for example, an organic solvent can also be used as an auxiliary solvent. 
     Examples of the liquid diluent or carrier include aromatic hydrocarbons (for example, xylene, toluene, alkylnaphthalene and the like), chlorinated aromatic or chlorinated aliphatic hydrocarbons (for example, chlorobenzenes, ethylene chlorides, methylene chlorides), aliphatic hydrocarbons (for example, cyclohexanes), paraffins (for example, mineral oil fractions), alcohols (for example, butanol, glycols and their ethers, esters and the like), ketones (for example, acetone, methyl ethyl ketone, methyl isobutyl ketone, cyclohexanone and the like), strongly polar solvents (for example, dimethylformamide, dimethylsulfoxide and the like), water and the like. The liquefied gas diluent or carrier may be those which are gaseous at normal temperature and normal pressure, for example, aerosol propellants such as butane, propane, nitrogen gas, carbon dioxide and halogenated hydrocarbons. Examples of the solid diluent include pulverized natural minerals (for example, kaolin, clay, talc, chalk, quartz, attapulgite, montmorillonite, diatomaceous earth, and the like), pulverized synthetic minerals (for example, highly dispersed silicic acid, alumina, silicates and the like), and the like. Examples of the solid carrier for granules include pulverized and screened rocks (for example, calcite, marble, pumice, sepiolite, dolomite and the like), synthetic granules of inorganic and organic powder, fine particles of organic materials (for example, sawdust, coconut shells, maize cobs, tobacco stalk and the like), and the like. Examples of the emulsifier and/or foaming agent include nonionic and anionic emulsifiers [for example, polyoxyethylene fatty acid esters, polyoxyethylene fatty acid alcohol ethers (for example, alkylaryl polyglycol ether), alkylsulfonates, alkylsulfates, arylsulfonates and the like], albumin hydro lyzate, and the like. Examples of the dispersant include lignin sulfite waste liquor and methylcellulose. 
     Fixing agents can also be used in the formulations (powders, granules, emulsions), and examples of the fixing agent include carboxymethylcellulose, natural and synthetic polymers (for example, gum arabic, polyvinyl alcohol, polyvinyl acetate, and the like) and the like. Colorants can also be used, and examples of the colorants include inorganic pigments (for example, iron oxide, titanium oxide, Prussian Blue and the like), organic dyes such as alizarin dyes, azo dyes or metal phthalocyanine dyes, and in addition, trace elements such as the salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc. The formulations in general can contain the active ingredient in an amount ranging from 0.1 to 95 percent by weight, and preferably 0.5 to 90 percent&gt; by weight. The compound according to the present invention can also exist as an admixture with other active compounds, for example, insecticides, poisonous baits, bactericides, miticides, nematicides, fungicides, growth regulators, herbicides and the like, in the form of their commercially useful formulation forms and in the application forms prepared from those formulations. 
     The content of the compound according to the present invention in a commercially useful application form can be varied within a wide range. 
     The concentration of the active compound according to the present invention in actual usage can be, for example, in the range of 0.0000001 to 100 percent by weight, and preferably 0.00001 to 1 percent by weight. 
     The compounds according to the present invention can be used through conventional methods that are appropriate for the usage form. 
     The active compound of the present invention have, when used against hygiene pests and pests associated with stored products, stability effective against alkali on lime materials, and also shows excellent residual effectiveness on wood and soil. The compounds of the invention may have favourable properties with respect to amount appled, residue formulation, selectivity, toxicity, production methodology, high activity, wide spectrum of control, safety, control of resistant organisms, e.g. pests that are resistant to organic phosphorus agents and/or carbamate agents. 
     Further embodiments of the invention are described below. 
     The compounds of formula (I) can be used to combat and control infestations of insect pests such as Lepidoptera, Diptera, Hemiptera, Thysanoptera, Orthoptera, Dictyoptera, Coleoptera, Siphonaptera, Hymenoptera and Isoptera and also other invertebrate pests, for example, acarine, nematode and mollusc pests. Insects, acarines, nematodes and molluscs are hereinafter collectively referred to as pests. The pests which may be combated and controlled by the use of the invention compounds include those pests associated with agriculture (which term includes the growing of crops for food and fiber products), horticulture and animal husbandry, companion animals, forestry and the storage of products of vegetable origin (such as fruit, grain and timber); those pests associated with the damage of man-made structures and the transmission of diseases of man and animals; and also nuisance pests (such as flies). 
     The compounds of the invention may be used for example on turf, ornamentals, such as flowers, shrubs, broad-leaved trees or evergreens, for example conifers, as well as for tree injection, pest management and the like. 
     The compounds of the invention may be used to control animal housing pests including: Ants, Bedbugs (adult), Bees, Beetles, Boxelder Bugs, Carpenter Bees, Carpet Beetles, Centipedes, Cigarette, Beetles, Clover Mites, Cockroaches, Confused Flour Beetle, Crickets, Earwigs, Firebrats, Fleas, Flies, Lesser Grain Borers, Millipedes, Mosquitoes, Red Flour Beetles, Rice Weevils, Saw-toothed Grain Beetles, Silverfish, Sowbugs, Spiders, Termites, Ticks, Wasps, Cockroaches, Crickets, Flies, Litter Beetles (such as Darkling, Hide, and Carrion), Mosquitoes, Pillbugs, Scorpions, Spiders, Spider Mites (Twospotted, Spruce), Ticks. 
     The compounds of the invention may be used to control ornamental pests including: Ants (Including Imported fire ants), Armyworms, Azalea caterpillars, Aphids, Bagworms, Black vine weevils (adult), Boxelder bugs, Budworms, California oakworms, Cankerworms, Cockroaches, Crickets, Cutworms, Eastern tent caterpillars, Elm leaf beetles, European sawflies, Fall webworms, Flea beetles, Forest tent caterpillars, Gypsy moth larvae, Japanese beetles (adults), June beetles (adults), Lace bugs, Leaf-feeding caterpillars, Leafhoppers, Leafminers (adults), Leaf rollers, Leaf skeletonizers, Midges, Mosquitoes, Oleander moth larvae, Pillbugs, Pine sawflies, Pine shoot beetles, Pinetip moths, Plant bugs, Root weevils, Sawflies, Scale insects (crawlers), Spiders, Spittlebugs, Striped beetles, Striped oakworms,  Thrips , Tip moths, Tussock moth larvae, Wasps, Broadmites, Brown softscales, California redscales (crawlers), Clover mites, Mealybugs, Pineneedlescales (crawlers), Spider mites, Whiteflies 
     The compounds of the invention may be used to control turf pests including: Ants (Including Imported fire ants, Armyworms, Centipedes, Crickets, Cutworms, Earwigs, Fleas (adult), Grasshoppers, Japanese beetles (adult), Millipedes, Mites, Mosquitoes (adult), Pillbugs, Sod webworms, Sow bugs, Ticks (including species which transmit Lyme disease), Bluegrass billbugs (adult), Black turfgrass ataenius (adult), Chiggers, Fleas (adult), Grubs (suppression), Hyperodes weevils (adult), Mole crickets (nymphs and young adults), Mole Crickets (mature adults), Chinch Bugs 
     Examples of pest species which may be controlled by the compounds of formula (I) include:  Myzus per sicae  (aphid),  Aphis gossypii  (aphid),  Aphis fabae  (aphid),  Lygus  spp. (capsids),  Dysdercus  spp. (capsids),  Nilaparvata lugens  (planthopper),  Nephotettixc incticeps  (leafhopper),  Nezara  spp. (stinkbugs),  Euschistus  spp. (stinkbugs),  Leptocorisa  spp. (stinkbugs),  Frankliniella occidentalis  (thrip),  Thrips  spp. (thrips),  Leptinotarsa decemlineata  (Colorado potato beetle),  Anthonomus grandis  (boll weevil),  Aonidiella  spp. (scale insects),  Trialeurodes  spp. (white flies),  Bemisia tabaci  (white fly),  Ostrinia nubilalis  (European corn borer),  Spodoptera littoralis  (cotton leafworm),  Heliothis virescens  (tobacco budworm),  Helicoverpa armigera  (cotton bollworm),  Helicoverpa zea  (cotton bollworm),  Sylepta derogata  (cotton leaf roller),  Pieris brassicae  (white butterfly),  Plutella xylostella  (diamond back moth),  Agrotis  spp. (cutworms),  Chilo suppressalis  (rice stem borer),  Locusta migratoria  (locust),  Chortiocetes terminifera  (locust),  Diabrotica  spp. (rootworms),  Panonychus ulmi  (European red mite),  Panonychus citri  (citrus red mite),  Tetranychus urticae  (two-spotted spider mite),  Tetranychus cinnabarinus  (carmine spider mite),  Phyllocoptruta oleivora  (citrus rust mite),  Polyphagotarsonemus latus  (broad mite),  Brevipalpus  spp. (flat mites),  Boophilus microplus  (cattle tick),  Dermacentor variabilis  (American dog tick),  Ctenocephalides felis  (cat flea),  Liriomyza  spp. (leafminer),  Musca domestica  (housefly),  Aedes aegypti  (mosquito),  Anopheles  spp. (mosquitoes),  Culex  spp. (mosquitoes),  Lucillia  spp. (blowflies),  Blattella germanica  (cockroach),  Periplaneta americana  (cockroach),  Blatta orientalis  (cockroach), termites of the  Mastotermitidae  (for example  Mastotermes  spp.), the  Kalotermitidae  (for example  Neotermes  spp.), the  Rhinotermitidae  (for example  Coptotermes formosanus, Reticulitermes flavipes, R. speratu, R. virginicus, R. hesperus , and  R. santonensis ) and the  Termitidae  (for example  Globitermes sulfureus ),  Solenopsis geminata  (fire ant),  Monomorium pharaonis  (pharaoh&#39;s ant),  Damalinia  spp. and  Linognathus  spp. (biting and sucking lice),  Meloidogyne  spp. (root knot nematodes),  Globodera  spp. and  Heterodera  spp. (cyst nematodes),  Pratylenchus  spp. (lesion nematodes),  Rhodopholus  spp. (banana burrowing nematodes),  Tylenchulus  spp. (citrus nematodes),  Haemonchus contortus  (barber pole worm),  Caenorhabditis elegans  (vinegar eelworm),  Trichostrongylus  spp. (gastro intestinal nematodes) and  Deroceras reticulatum  (slug). 
     The compounds of the invention may be used for pest control on various plants, including soybean (e.g. in some cases 10-70 g/ha), corn (e.g. in some cases 10-70 g/ha), sugarcane (e.g. in some cases 20-200 g/ha), alfalfa (e.g. in some cases 10-70 g/ha), brassicas (e.g. in some cases 10-50 g/ha), oilseed rape (e.g. canola) (e.g. in some cases 20-70 g/ha), potatoes (including sweet potatoes) (e.g. in some cases 10-70 g/ha), cotton (e.g. in some cases 10-70 g/ha), rice (e.g. in some cases 10-70 g/ha), coffee (e.g. in some cases 30-150 g/ha), citrus (e.g. in some cases 60-200 g/ha), almonds (e.g. in some cases 40-180 g/ha), fruiting vegetables (e.g. tomatoes, pepper, chili, eggplant, cucumber, squash etc.) (e.g. in some cases 10-80 g/ha), tea (e.g. in some cases 20-150 g/ha), bulb vegetables (e.g. onion, leek etc.) (e.g. in some cases 30-90 g/ha), grapes (e.g. in some cases 30-180 g/ha), pome fruit (e.g. apples, pears etc.) (e.g. in some cases 30-180 g/ha), and stone fruit (e.g. pears, plums etc.) (e.g. in some cases 30-180 g/ha). 
     The compounds of the invention may be used on soybean to control, for example,  Elasmopalpus lignosellus, Diloboderus abderus, Diabrotica speciosa, Sternechus subsignatus, Formicidae, Agrotis ypsilon, Julus  ssp.,  Anticarsia gemmatalis, Megascelis  ssp.,  Procornitermes  ssp.,  Gryllotalpidae, Nezara viridula, Piezodorus  spp.,  Acrosternum  spp.,  Neomegalotomus  spp.,  Cerotoma trifurcata, Popillia japonica, Edessa  spp.,  Liogenys fuscus, Euchistus heros, stalk borer, Scaptocoris castanea, phyllophaga  spp.,  Pseudoplusia includens, Spodoptera  spp.,  Bemisia tabaci, Agriotes  spp. The compounds of the invention are preferably used on soybean to control  Diloboderus abderus, Diabrotica speciosa, Nezara viridula, Piezodorus  spp.,  Acrosternum  spp.,  Cerotoma trifurcata, Popillia japonica, Euchistus heros, Phyllophaga  spp.,  Agriotes  spp. 
     The compounds of the invention may be used on corn to control, for example,  Euchistus heros, Dichelops furcatus, Diloboderus abderus, Elasmopalpus lignosellus, Spodoptera frupperda, Nezara viridula, Cerotoma trifurcata, Popillia japonica, Agrotis ypsilon, Diabrotica speciosa, Heteroptera, Procornitermes  ssp.,  Scaptocoris castanea, Formicidae, Julus  ssp.,  Dalbulus maidis, Diabrotica virgifera, Mocis latipes, Bemisia tabaci, heliothis  spp.,  Tetranychus  spp.,  Thrips  spp.,  phyllophaga  spp.,  scaptocoris  spp.,  Liogenys fuscus, Spodoptera  spp.,  Ostrinia  spp.,  Sesamia  spp.,  Agriotes  spp. The compounds of the invention are preferably used on corn to control  Euchistus heros, Dichelops furcatus, Diloboderus abderus, Nezara viridula, Cerotoma trifurcata, Popillia japonica, Diabrotica speciosa, Diabrotica virgifera, Tetranychus  spp.,  Thrips  spp.,  Phyllophaga  spp.,  Scaptocoris  spp.,  Agriotes  spp. 
     The compounds of the invention may be used on sugar cane to control, for example,  Sphenophorus  spp., termites,  Mahanarva  spp. The compounds of the invention are preferably used on sugar cane to control termites,  Mahanarva  spp. 
     The compounds of the invention may be used on alfalfa to control, for example,  Hypera brunneipennis, Hypera postica, Colias eurytheme, Collops  spp.,  Empoasca solana, Epitrix, Geocoris  spp.,  Lygus hesperus, Lygus lineolaris, Spissistilus spp, Spodoptera  spp.,  Trichoplusia ni . The compounds of the invention are preferably used on alfalfa to control  Hypera brunneipennis, Hypera postica, Empoasca solana, Epitrix, Lygus hesperus, Lygus lineolaris, Trichoplusia ni.    
     The compounds of the invention may be used on brassicas to control, for example,  Plutella xylostella, Pieris  spp.,  Mamestra  spp.,  Plusia  spp.,  Trichoplusia ni, Phyllotreta  spp.,  Spodoptera  spp.,  Empoasca solana, Thrips  spp.,  Spodoptera  spp.,  Delia  spp. The compounds of the invention are preferably used on brassicas to control  Plutella xylostella Pieris  spp.,  Plusia  spp.,  Trichoplusia ni, Phyllotreta  spp.,  Thrips  spp. 
     The compounds of the invention may be used on oil seed rape, e.g. canola, to control, for example,  Meligethes  spp.,  Ceutorhynchus napi, Psylloides  spp. 
     The compounds of the invention may be used on potatoes, including sweet potatoes, to control, for example,  Empoasca  spp.,  Leptinotarsa  spp.,  Diabrotica speciosa, Phthorimaea  spp.,  Paratrioza  spp.,  Maladera matrida, Agriotes  spp. The compounds of the invention are preferably used on potatoes, including sweet potatoes, to control  Empoasca  spp.,  Leptinotarsa  spp.,  Diabrotica speciosa, Phthorimaea  spp.,  Paratrioza  spp.,  Agriotes  spp. 
     The compounds of the invention may be used on cotton to control, for example,  Anthonomus grandis, Pectinophora  spp.,  Heliothis  spp.,  Spodoptera  spp.,  Tetranychus  spp.,  Empoasca  spp.,  Thrips  spp.,  Bemisia tabaci, Lygus  spp.,  Phyllophaga  spp.,  Scaptocoris  spp. The compounds of the invention are preferably used on cotton to control  Anthonomus grandis, Tetranychus  spp.,  Empoasca  spp.,  Thrips  spp.,  Lygus  spp.,  phyllophaga  spp.,  Scaptocoris  spp. 
     The compounds of the invention may be used on rice to control, for example,  Leptocorisa  spp.,  Cnaphalocrosis  spp.,  Chilo  spp.,  Scirpophaga  spp.,  Lissorhoptrus  spp.,  Oebalus pugnax . The compounds of the invention are preferably used on rice to control  Leptocorisa  spp.,  Lissorhoptrus  spp.,  Oebalus pugnax.    
     The compounds of the invention may be used on coffee to control, for example,  Hypothenemus Hampei, Perileucoptera Coffeella, Tetranychus  spp. The compounds of the invention are preferably used on coffee to control  Hypothenemus Hampei, Perileucoptera coffeella.    
     The compounds of the invention may be used on citrus to control, for example,  Panonychus citri, Phyllocoptruta oleivora, Brevipalpus  spp.,  Diaphorina citri, Scirtothrips  spp.,  Thrips  spp.,  Unaspis  spp.,  Ceratitis capitata, Phyllocnistis  spp. The compounds of the invention are preferably used on citrus to control  Panonychus citri, Phyllocoptruta oleivora, Brevipalpus  spp.,  Diaphorina citri, Scirtothrips  spp.,  Thrips  spp.,  Phyllocnistis  spp. 
     The compounds of the invention may be used on almonds to control, for example,  Amyelois transitella, Tetranychus  spp. 
     The compounds of the invention may be used on fruiting vegetable, including tomatoes, pepper, chili, eggplant, cucumber, squash etc, to control  Thrips  spp.,  Tetranychus  spp.,  Polyphagotarsonemus  spp.,  Aculops  spp.,  Empoasca  spp.,  Spodoptera  spp.,  Heliothis  spp.,  Tuta absoluta, Liriomyza  spp.,  Bemisia tabaci, Trialeurodes  spp.,  Paratrioza  spp.,  Frankliniella occidentalis, Frankliniella  spp.,  Anthonomus  spp.,  Phyllotreta  spp.,  Amrasca  spp.,  Epilachna  spp.,  Halyomorpha  spp.,  Scirtothrips  spp.,  Leucinodes  spp.,  Neoleucinodes  spp. The compounds of the invention are preferably used on fruiting vegetable, including tomatoes, pepper, chili, eggplant, cucumber, squash etc, to control, for example,  Thrips  spp.,  Tetranychus  spp.,  Polyphagotarsonemus  spp.,  Aculops  spp.,  Empoasca  spp.,  Spodoptera  spp.,  Heliothis  spp.,  Tuta absoluta, Liriomyza  spp.,  Paratrioza  spp.,  Frankliniella occidentalis, Frankliniella  spp.,  Amrasca  spp.,  Scirtothrips  spp.,  Leucinodes  spp.,  Neoleucinodes  spp. 
     The compounds of the invention may be used on tea to control, for example,  Pseudaulacaspis  spp.,  Empoasca  spp.,  Scirtothrips  spp.,  Caloptilia theivora . The compounds of the invention are prefrerably used on tea to control  Empoasca  spp.,  Scirtothrips  spp. 
     The compounds of the invention may be used on bulb vegetables, including onion, leek etc to control, for example,  Thrips  spp.,  Spodoptera  spp.,  Heliothis  spp. The compounds of the invention are preferably used on bulb vegetables, including onion, leek etc to control  Thrips  spp. 
     The compounds of the invention may be used on grapes to control, for example,  Empoasca  spp.,  Lobesia  spp.,  Frankliniella  spp.,  Thrips  spp.,  Tetranychus  spp.,  Rhipiphorothrips Cruentatus, Eotetranychus Willamettei, Erythroneura Elegantula, Scaphoides  spp. The compounds of the invention are preferably used on grapes to control  Frankliniella  spp.,  Thrips  spp.,  Tetranychus  spp.,  Rhipiphorothrips Cruentatus, Scaphoides  spp. 
     The compounds of the invention may be used on pome fruit, including apples, pairs etc, to control, for example,  Cacopsylla  spp.,  Psylla  spp.,  Panonychus ulmi, Cydia pomonella . The compounds of the invention are preferably used on pome fruit, including apples, pairs etc, to control  Cacopsylla  spp.,  Psylla  spp.,  Panonychus ulmi.    
     The compounds of the invention may be used on stone fruit to control, for example,  Grapholita molesta, Scirtothrips  spp.,  Thrips  spp.,  Frankliniella  spp.,  Tetranychus  spp. The compounds of the invention are preferably used on stone fruit to control  Scirtothrips  spp.,  Thrips  spp.,  Frankliniella  spp.,  Tetranychus  spp. The invention therefore provides a method of combating and/or controlling an animal pest, e.g. an invertebrate animal pest, which comprises applying to the pest, to a locus of the pest, or to a plant susceptible to attack by the pest a pesticidally effective amount of a compound of formula (I). In particular, the invention provides a method of combating and/or controlling insects, acarines, nematodes or molluscs which comprises applying an insecticidally, acaricidally, nematicidally or molluscicidally effective amount of a compound of formula (I), or a composition containing a compound of formula (I), to a pest, a locus of pest, preferably a plant, or to a plant susceptible to attack by a pest, The compounds of formula (I) are preferably used against insects, acarines or nematodes. 
     The term “plant” as used herein includes seedlings, bushes and trees. Crops are to be understood as also including those crops which have been rendered tolerant to herbicides or classes of herbicides (e.g. ALS-, GS-, EPSPS-, PPO- and HPPD-inhibitors) by conventional methods of breeding or by genetic engineering. An example of a crop that has been rendered tolerant to imidazolinones, e.g. imazamox, by conventional methods of breeding is Clearfield® summer rape (canola). Examples of crops that have been rendered tolerant to herbicides by genetic engineering methods include e.g. glyphosate- and glufosinate-resistant maize varieties commercially available under the trade names RoundupReady® and LibertyLink®. 
     Crops are also to be understood as being those which have been rendered resistant to harmful insects by genetic engineering methods, for example Bt maize (resistant to European corn borer), Bt cotton (resistant to cotton boll weevil) and also Bt potatoes (resistant to Colorado beetle). Examples of Bt maize are the Bt 176 maize hybrids of NK® (Syngenta Seeds). Examples of transgenic plants comprising one or more genes that code for an insecticidal resistance and express one or more toxins are KnockOut® (maize), Yield Gard® (maize), NuCOTIN33B® (cotton), Bollgard® (cotton), NewLeaf® (potatoes), NatureGard® and Protexcta®. Plant crops or seed material thereof can be both resistant to herbicides and, at the same time, resistant to insect feeding (“stacked” transgenic events). For example, seed can have the ability to express an insecticidal Cry3 protein while at the same time being tolerant to glyphosate. 
     Crops are also to be understood as being those which are obtained by conventional methods of breeding or genetic engineering and contain so-called output traits (e.g. improved storage stability, higher nutritional value and improved flavor). 
     In order to apply a compound of formula (I) as an insecticide, acaricide, nematicide or molluscicide to a pest, a locus of pest, or to a plant susceptible to attack by a pest, a compound of formula (I) is usually formulated into a composition which includes, in addition to the compound of formula (I), a suitable inert diluent or carrier and, optionally, a surface active agent (SFA). SFAs are chemicals which are able to modify the properties of an interface (for example, liquid/solid, liquid/air or liquid/liquid interfaces) by lowering the interfacial tension and thereby leading to changes in other properties (for example dispersion, emulsification and wetting). It is preferred that all compositions (both solid and liquid formulations) comprise, by weight, 0.0001 to 95%, more preferably 1 to 85%, for example 5 to 60%, of a compound of formula (I). The composition is generally used for the control of pests such that a compound of formula (I) is applied at a rate of from 0.1 g to 10 kg per hectare, preferably from 1 g to 6 kg per hectare, more preferably from 1 g to 1 kg per hectare. 
     When used in a seed dressing, a compound of formula (I) is generally used at a rate of 0.0001 g to 10 g (for example 0.001 g or 0.05 g), preferably 0.005 g to 10 g, more preferably 0.005 g to 4 g, per kilogram of seed. 
     In another aspect the present invention provides a composition comprising a pesticidally effective amount of a compound of formula (I), in particular an insecticidal, acaricidal, nematicidal or molluscicidal composition comprising an insecticidally, acaricidally, nematicidally or molluscicidally effective amount of a compound of formula (I) and a suitable carrier or diluent therefor. The composition is preferably an insecticidal, acaricidal, nematicidal or molluscicidal composition. 
     The compositions can be chosen from a number of formulation types, including dustable powders (DP), soluble powders (SP), water soluble granules (SG), water dispersible granules (WG), wettable powders (WP), granules (GR) (slow or fast release), soluble concentrates (SL), oil miscible liquids (OL), ultra low volume liquids (UL), emulsifiable concentrates (EC), dispersible concentrates (DC), emulsions (both oil in water (EW) and water in oil (EO)), micro-emulsions (ME), suspension concentrates (SC), aerosols, fogging/smoke formulations, capsule suspensions (CS) and seed treatment formulations. The formulation type chosen in any instance will depend upon the particular purpose envisaged and the physical, chemical and biological properties of the compound of formula (I). 
     Dustable powders (DP) may be prepared by mixing a compound of formula (I) with one or more solid diluents (for example natural clays, kaolin, pyrophyllite, bentonite, alumina, montmorillonite, kieselguhr, chalk, diatomaceous earths, calcium phosphates, calcium and magnesium carbonates, sulfur, lime, flours, talc and other organic and inorganic solid carriers) and mechanically grinding the mixture to a fine powder. 
     Soluble powders (SP) may be prepared by mixing a compound of formula (I) with one or more water-soluble inorganic salts (such as sodium bicarbonate, sodium carbonate or magnesium sulfate) or one or more water-soluble organic solids (such as a polysaccharide) and, optionally, one or more wetting agents, one or more dispersing agents or a mixture of said agents to improve water dispersibility/solubility. The mixture is then ground to a fine powder. Similar compositions may also be granulated to form water soluble granules (SG). 
     Wettable powders (WP) may be prepared by mixing a compound of formula (I) with one or more solid diluents or carriers, one or more wetting agents and, preferably, one or more dispersing agents and, optionally, one or more suspending agents to facilitate the dispersion in liquids. The mixture is then ground to a fine powder. Similar compositions may also be granulated to form water dispersible granules (WG). 
     Granules (GR) may be formed either by granulating a mixture of a compound of formula (I) and one or more powdered solid diluents or carriers, or from pre-formed blank granules by absorbing a compound of formula (I) (or a solution thereof, in a suitable agent) in a porous granular material (such as pumice, attapulgite clays, fuller&#39;s earth, kieselguhr, diatomaceous earths or ground corn cobs) or by adsorbing a compound of formula (I) (or a solution thereof, in a suitable agent) on to a hard core material (such as sands, silicates, mineral carbonates, sulfates or phosphates) and drying if necessary. Agents which are commonly used to aid absorption or adsorption include solvents (such as aliphatic and aromatic petroleum solvents, alcohols, ethers, ketones and esters) and sticking agents (such as polyvinyl acetates, polyvinyl alcohols, dextrins, sugars and vegetable oils). One or more other additives may also be included in granules (for example an emulsifying agent, wetting agent or dispersing agent). 
     Dispersible Concentrates (DC) may be prepared by dissolving a compound of formula (I) in water or an organic solvent, such as a ketone, alcohol or glycol ether. These solutions may contain a surface active agent (for example to improve water dilution or prevent crystallization in a spray tank). 
     Emulsifiable concentrates (EC) or oil-in-water emulsions (EW) may be prepared by dissolving a compound of formula (I) in an organic solvent (optionally containing one or more wetting agents, one or more emulsifying agents or a mixture of said agents). Suitable organic solvents for use in ECs include aromatic hydrocarbons (such as alkylbenzenes or alkylnaphthalenes, exemplified by SOLVESSO 100, SOLVESSO 150 and SOLVESSO 200; SOLVESSO is a Registered Trade Mark), ketones (such as cyclohexanone or methylcyclohexanone) and alcohols (such as benzyl alcohol, furfuryl alcohol or butanol), N-alkylpyrrolidones (such as N-methylpyrrolidone or N-octylpyrrolidone), dimethyl amides of fatty acids (such as C 8 -C 10  fatty acid dimethylamide) and chlorinated hydrocarbons. An EC product may spontaneously emulsify on addition to water, to produce an emulsion with sufficient stability to allow spray application through appropriate equipment. Preparation of an EW involves obtaining a compound of formula (I) either as a liquid (if it is not a liquid at room temperature, it may be melted at a reasonable temperature, typically below 70° C.) or in solution (by dissolving it in an appropriate solvent) and then emulsifiying the resultant liquid or solution into water containing one or more SFAs, under high shear, to produce an emulsion. Suitable solvents for use in EWs include vegetable oils, chlorinated hydrocarbons (such as chlorobenzenes), aromatic solvents (such as alkylbenzenes or alkylnaphthalenes) and other appropriate organic solvents which have a low solubility in water. 
     Microemulsions (ME) may be prepared by mixing water with a blend of one or more solvents with one or more SFAs, to produce spontaneously a thermodynamically stable isotropic liquid formulation. A compound of formula (I) is present initially in either the water or the solvent/SFA blend. Suitable solvents for use in MEs include those hereinbefore described for use in ECs or in EWs. An ME may be either an oil-in-water or a water-in-oil system (which system is present may be determined by conductivity measurements) and may be suitable for mixing water-soluble and oil-soluble pesticides in the same formulation. An ME is suitable for dilution into water, either remaining as a microemulsion or forming a conventional oil-in-water emulsion. 
     Suspension concentrates (SC) may comprise aqueous or non-aqueous suspensions of finely divided insoluble solid particles of a compound of formula (I). SCs may be prepared by ball or bead milling the solid compound of formula (I) in a suitable medium, optionally with one or more dispersing agents, to produce a fine particle suspension of the compound. One or more wetting agents may be included in the composition and a suspending agent may be included to reduce the rate at which the particles settle. Alternatively, a compound of formula (I) may be dry milled and added to water, containing agents hereinbefore described, to produce the desired end product. 
     Aerosol formulations comprise a compound of formula (I) and a suitable propellant (for example n-butane). A compound of formula (I) may also be dissolved or dispersed in a suitable medium (for example water or a water miscible liquid, such as n-propanol) to provide compositions for use in non-pressurized, hand-actuated spray pumps. 
     A compound of formula (I) may be mixed in the dry state with a pyrotechnic mixture to form a composition suitable for generating, in an enclosed space, a smoke containing the compound. 
     Capsule suspensions (CS) may be prepared in a manner similar to the preparation of EW formulations but with an additional polymerization stage such that an aqueous dispersion of oil droplets is obtained, in which each oil droplet is encapsulated by a polymeric shell and contains a compound of formula (I) and, optionally, a carrier or diluent therefor. The polymeric shell may be produced by either an interfacial polycondensation reaction or by a coacervation procedure. The compositions may provide for controlled release of the compound of formula (I) and they may be used for seed treatment. A compound of formula (I) may also be formulated in a biodegradable polymeric matrix to provide a slow, controlled release of the compound. 
     A composition may include one or more additives to improve the biological performance of the composition (for example by improving wetting, retention or distribution on surfaces; resistance to rain on treated surfaces; or uptake or mobility of a compound of formula (I)). Such additives include surface active agents, spray additives based on oils, for example certain mineral oils or natural plant oils (such as soy bean and rape seed oil), and blends of these with other bio-enhancing adjuvants (ingredients which may aid or modify the action of a compound of formula (I)). 
     A compound of formula (I) may also be formulated for use as a seed treatment, for example as a powder composition, including a powder for dry seed treatment (DS), a water soluble powder (SS) or a water dispersible powder for slurry treatment (WS), or as a liquid composition, including a flowable concentrate (FS), a solution (LS) or a capsule suspension (CS). The preparations of DS, SS, WS, FS and LS compositions are very similar to those of, respectively, DP, SP, WP, SC and DC compositions described above. Compositions for treating seed may include an agent for assisting the adhesion of the composition to the seed (for example a mineral oil or a film-forming barrier). 
     Wetting agents, dispersing agents and emulsifying agents may be surface SFAs of the cationic, anionic, amphoteric or non-ionic type. 
     Suitable SFAs of the cationic type include quaternary ammonium compounds (for example cetyltrimethyl ammonium bromide), imidazolines and amine salts. 
     Suitable anionic SFAs include alkali metals salts of fatty acids, salts of aliphatic monoesters of sulfuric acid (for example sodium lauryl sulfate), salts of sulfonated aromatic compounds (for example sodium dodecylbenzenesulfonate, calcium dodecylbenzenesulfonate, butylnaphthalene sulfonate and mixtures of sodium di-isopropyl- and tri-isopropyl-naphthalene sulfonates), ether sulfates, alcohol ether sulfates (for example sodium laureth-3-sulfate), ether carboxylates (for example sodium laureth-3-carboxylate), phosphate esters (products from the reaction between one or more fatty alcohols and phosphoric acid (predominately mono-esters) or phosphorus pentoxide (predominately di-esters), for example the reaction between lauryl alcohol and tetraphosphoric acid; additionally these products may be ethoxylated), sulfosuccinamates, paraffin or olefine sulfonates, taurates and lignosulfonates. 
     Suitable SFAs of the amphoteric type include betaines, propionates and glycinates. 
     Suitable SFAs of the non-ionic type include condensation products of alkylene oxides, such as ethylene oxide, propylene oxide, butylene oxide or mixtures thereof, with fatty alcohols (such as oleyl alcohol or cetyl alcohol) or with alkylphenols (such as octylphenol, nonylphenol or octylcresol); partial esters derived from long chain fatty acids or hexitol anhydrides; condensation products of said partial esters with ethylene oxide; block polymers (comprising ethylene oxide and propylene oxide); alkanolamides; simple esters (for example fatty acid polyethylene glycol esters); amine oxides (for example lauryl dimethyl amine oxide); and lecithins. 
     Suitable suspending agents include hydrophilic colloids (such as polysaccharides, polyvinylpyrrolidone or sodium carboxymethylcellulose) and swelling clays (such as bentonite or attapulgite). 
     A compound of formula (I) may be applied by any of the known means of applying pesticidal compounds. For example, it may be applied, formulated or unformulated, to the pests or to a locus of the pests (such as a habitat of the pests, or a growing plant liable to infestation by the pests) or to any part of the plant, including the foliage, stems, branches or roots, to the seed before it is planted or to other media in which plants are growing or are to be planted (such as soil surrounding the roots, the soil generally, paddy water or hydroponic culture systems), directly or it may be sprayed on, dusted on, applied by dipping, applied as a cream or paste formulation, applied as a vapor or applied through distribution or incorporation of a composition (such as a granular composition or a composition packed in a water-soluble bag) in soil or an aqueous environment. 
     A compound of formula (I) may also be injected into plants or sprayed onto vegetation using electrodynamic spraying techniques or other low volume methods, or applied by land or aerial irrigation systems. 
     Compositions for use as aqueous preparations (aqueous solutions or dispersions) are generally supplied in the form of a concentrate containing a high proportion of the active ingredient, the concentrate being added to water before use. These concentrates, which may include DCs, SCs, ECs, EWs, MEs, SGs, SPs, WPs, WGs and CSs, are often required to withstand storage for prolonged periods and, after such storage, to be capable of addition to water to form aqueous preparations which remain homogeneous for a sufficient time to enable them to be applied by conventional spray equipment. Such aqueous preparations may contain varying amounts of a compound of formula (I) (for example 0.0001 to 10%, by weight) depending upon the purpose for which they are to be used. 
     A compound of formula (I) may be used in mixtures with fertilizers (for example nitrogen-, potassium- or phosphorus-containing fertilizers). Suitable formulation types include granules of fertilizer. The mixtures preferably contain up to 25% by weight of the compound of formula (I). 
     The invention therefore also provides a fertilizer composition comprising a fertilizer and a compound of formula (I). 
     The compositions of this invention may contain other compounds having biological activity, for example micronutrients or compounds having fungicidal activity or which possess plant growth regulating, herbicidal, insecticidal, nematicidal or acaricidal activity. 
     The compound of formula (I) may be the sole active ingredient of the composition or it may be admixed with one or more additional active ingredients such as a pesticide, e.g. a insecticide, fungicide or herbicide, or a synergist or plant growth regulator where appropriate. An additional active ingredient may provide a composition having a broader spectrum of activity or increased persistence at a locus; synergize the activity or complement the activity (for example by increasing the speed of effect or overcoming repellency) of the compound of formula (I); or help to overcome or prevent the development of resistance to individual components. The particular additional active ingredient will depend upon the intended utility of the composition. 
     The compounds of the invention are also useful in the field of animal health, e.g. they may be used against parasitic invertebrate pests, more preferably against parasitic invertebrate pests in or on an animal. Examples of pests include nematodes, trematodes, cestodes, flies, mites, tricks, lice, fleas, true bugs and maggots. The animal may be a non-human animal, e.g. an animal associated with agriculture, e.g. a cow, a pig, a sheep, a goat, a horse, or a donkey, or a companion animal, e.g. a dog or a cat. 
     In a further aspect the invention provides a compound of the invention for use in a method of therapeutic treatment. 
     In a further aspect the invention relates to a method of controlling parasitic invertebrate pests in or on an animal comprising administering a pesticidally effective amount of a compound of the invention. The administration may be for example oral administration, parenteral administration or external administration, e.g. to the surface of the animal body. In a further aspect the invention relates to a compound of the invention for controlling parasitic invertebrate pests in or on an animal. In a further aspect the invention relates to use of a compound of the invention in the manufacture of a medicament for controlling parasitic invertebrate pests in or on an animal 
     In a further aspect, the invention relates to a method of controlling parasitic invertebrate pests comprising administering a pesticidally effective amount of a compound of the invention to the environment in which an animal resides. 
     In a further aspect the invention relates to a method of protecting an animal from a parasitic invertebrate pest comprising administering to the animal a pesticidally effective amount of a compound of the invention. In a further aspect the invention relates to a compound of the invention for use in protecting an animal from a parasitic invertebrate pest. In a further aspect the invention relates to use of a compound of the invention in the manufacture of a medicament for protecting an animal from a parasitic invertebrate pest. 
     In a further aspect the invention provides a method of treating an animal suffering from a parasitic invertebrate pest comprising administering to the animal a pesticidally effective amount of a compound of the invention. In a further aspect the invention relates to a compound of the invention for use in treating an animal suffering from a parasitic invertebrate pest. In a further aspect the invention relates to use of a compound of the invention in the manufacture of a medicament for treating an animal suffering from a parasitic invertebrate pest. 
     In a further aspect, the invention provides a pharmaceutical composition comprising a compound of the invention and a pharmaceutically suitable excipient. 
     The compounds of the invention may be used alone or in combination with one or more other biologically active ingredients. 
     In one aspect the invention provides a combination product comprising a pesticidally effective amount of a component A and a pesticidally effective amount of component B wherein component A is a compound of the invention and component B is a compound as described below. 
     The compounds of the invention may be used in combination with anthelmintic agents. Such anthelmintic agents include, compounds selected from the macrocyclic lactone class of compounds such as ivermectin, avermectin, abamectin, emamectin, eprinomectin, doramectin, selamectin, moxidectin, nemadectin and milbemycin derivatives as described in EP-357460, EP-444964 and EP-594291. Additional anthelmintic agents include semisynthetic and biosynthetic avermectin/milbemycin derivatives such as those described in U.S. Pat. No. 5,015,630, WO-9415944 and WO-9522552. Additional anthelmintic agents include the benzimidazoles such as albendazole, cambendazole, fenbendazole, flubendazole, mebendazole, oxfendazole, oxibendazole, parbendazole, and other members of the class. Additional anthelmintic agents include imidazothiazoles and tetrahydropyrimidines such as tetramisole, levamisole, pyrantel pamoate, oxantel or morantel. Additional anthelmintic agents include flukicides, such as triclabendazole and clorsulon and the cestocides, such as praziquantel and epsiprantel. 
     The compounds of the invention may be used in combination with derivatives and analogues of the paraherquamide/marcfortine class of anthelmintic agents, as well as the antiparasitic oxazolines such as those disclosed in U.S. Pat. No. 5,478,855, U.S. Pat. No. 4,639,771 and DE-19520936. 
     The compounds of the invention may be used in combination with derivatives and analogues of the general class of dioxomorpholine antiparasitic agents as described in WO-9615121 and also with anthelmintic active cyclic depsipeptides such as those described in WO-9611945, WO-9319053, WO-9325543, EP-626375, EP-382173, WO-9419334, EP-382173, and EP-503538. 
     The compounds of the invention may be used in combination with other ectoparasiticides; for example, fipronil; pyrethroids; organophosphates; insect growth regulators such as lufenuron; ecdysone agonists such as tebufenozide and the like; neonicotinoids such as imidacloprid and the like. 
     The compounds of the invention may be used in combination with terpene alkaloids, for example those described in International Patent Application Publication Numbers WO95/19363 or WO04/72086, particularly the compounds disclosed therein. 
     Other examples of such biologically active compounds that the compounds of the invention may be used in combination with include but are not restricted to the following: 
     Organophosphates: acephate, azamethiphos, azinphos-ethyl, azinphos-methyl, bromophos, bromophos-ethyl, cadusafos, chlorethoxyphos, chlorpyrifos, chlorfenvinphos, chlormephos, demeton, demeton-S-methyl, demeton-S-methyl sulphone, dialifos, diazinon, dichlorvos, dicrotophos, dimethoate, disulfoton, ethion, ethoprophos, etrimfos, famphur, fenamiphos, fenitrothion, fensulfothion, fenthion, flupyrazofos, fonofos, formothion, fosthiazate, heptenophos, isazophos, isothioate, isoxathion, malathion, methacriphos, methamidophos, methidathion, methyl-parathion, mevinphos, monocrotophos, naled, omethoate, oxydemeton-methyl, paraoxon, parathion, parathion-methyl, phenthoate, phosalone, phosfolan, phosphocarb, phosmet, phosphamidon, phorate, phoxim, pirimiphos, pirimiphos-methyl, profenofos, propaphos, proetamphos, prothiofos, pyraclofos, pyridapenthion, quinalphos, sulprophos, temephos, terbufos, tebupirimfos, tetrachlorvinphos, thimeton, triazophos, trichlorfon, vamidothion. 
     Carbamates: alanycarb, aldicarb, 2-sec-butylphenyl methylcarbamate, benfuracarb, carbaryl, carbofuran, carbosulfan, cloethocarb, ethiofencarb, fenoxycarb, fenthiocarb, furathiocarb, HCN-801, isoprocarb, indoxacarb, methiocarb, methomyl, 5-methyl-m-cumenylbutyryl(methyl)carbamate, oxamyl, pirimicarb, propoxur, thiodicarb, thiofanox, triazamate, UC-51717. 
     Pyrethroids: acrinathin, allethrin, alphametrin, 5-benzyl-3-furylmethyl (E)-(1R)-cis-2,2-dimethyl-3-(2-oxothiolan-3-ylidenemethyl)cyclopropanecarboxylate, bifenthrin, beta-cyfluthrin, cyfluthrin, a-cypermethrin, beta-cypermethrin, bioallethrin, bioallethrin((S)-cyclopentylisomer), bioresmethrin, bifenthrin, NCI-85193, cycloprothrin, cyhalothrin, cythithrin, cyphenothrin, deltamethrin, empenthrin, esfenvalerate, ethofenprox, fenfluthrin, fenpropathrin, fenvalerate, flucythrinate, flumethrin, fluvalinate (D isomer), imiprothrin, cyhalothrin, lambda-cyhalothrin, permethrin, phenothrin, prallethrin, pyrethrins (natural products), resmethrin, tetramethrin, transfluthrin, theta-cypermethrin, silafluofen, t-fluvalinate, tefluthrin, tralomethrin, Zeta-cypermethrin. 
     Arthropod growth regulators: a) chitin synthesis inhibitors: benzoylureas: chlorfluazuron, diflubenzuron, fluazuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, teflubenzuron, triflumuron, buprofezin, diofenolan, hexythiazox, etoxazole, chlorfentazine; b) ecdysone antagonists: halofenozide, methoxyfenozide, tebufenozide; c) juvenoids: pyriproxyfen, methoprene (including S-methoprene), fenoxycarb; d) lipid biosynthesis inhibitors: spirodiclofen. 
     Other antiparasitics: acequinocyl, amitraz, AKD-1022, ANS-118, azadirachtin,  Bacillus thuringiensis , bensultap, bifenazate, binapacryl, bromopropylate, BTG-504, BTG-505, camphechlor, cartap, chlorobenzilate, chlordimeform, chlorfenapyr, chromafenozide, clothianidine, cyromazine, diacloden, diafenthiuron, DBI-3204, dinactin, dihydroxymethyldihydroxypyrrolidine, dinobuton, dinocap, endosulfan, ethiprole, ethofenprox, fenazaquin, flumite, MTI-800, fenpyroximate, fluacrypyrim, flubenzimine, flubrocythrinate, flufenzine, flufenprox, fluproxyfen, halofenprox, hydramethylnon, kanemite, NC-196, neem guard, nidinorterfuran, nitenpyram, SD-35651, WL-108477, pirydaryl, propargite, protrifenbute, pymethrozine, pyridaben, pyrimidifen, NC-1111, R-195, RH-0345, RH-2485, RYI-210, S-1283, S-1833, SI-8601, silafluofen, silomadine, spinosad, tebufenpyrad, tetradifon, tetranactin, thiacloprid, thiocyclam, thiamethoxam, tolfenpyrad, triazamate, triethoxyspinosyn, trinactin, verbutin, vertalec, yl-5301. 
     Fungicides: acibenzolar, aldimorph, ampropylfos, andoprim, azaconazole, azoxystrobin, benalaxyl, benomyl, bialaphos, blasticidin-S, Bordeaux mixture, bromuconazole, bupirimate, carpropamid, captafol, captan, carbendazim, chlorfenazole, chloroneb, chloropicrin, chlorothalonil, chlozolinate, copper oxychloride, copper salts, cyflufenamid, cymoxanil, cyproconazole, cyprodinil, cyprofuram, RH-7281, diclocymet, diclobutrazole, diclomezine, dicloran, difenoconazole, RP-407213, dimethomorph, domoxystrobin, diniconazole, diniconazole-M, dodine, edifenphos, epoxiconazole, famoxadone, fenamidone, fenarimol, fenbuconazole, fencaramid, fenpiclonil, fenpropidin, fenpropimorph, fentin acetate, fluazinam, fludioxonil, flumetover, flumorf/flumorlin, fentin hydroxide, fluoxastrobin, fluquinconazole, flusilazole flutolanil flutriafol, folpet, fosetyl-aluminium, furalaxyl, furametapyr, hexaconazole, ipconazole, iprobenfos, iprodione, isoprothiolane, kasugamycin, krsoxim-methyl, mancozeb, maneb, mefenoxam, mepronil, metalaxyl, metconazole, metominostrobin/fenominostrobin, metrafenone, myclobutanil, neo-asozin, nicobifen, orysastrobin, oxadixyl, penconazole, pencycuron, probenazole, prochloraz, propamocarb, propioconazole, proquinazid, prothioconazole, pyrifenox, pyraclostrobin, pyrimethanil, pyroquilon, quinoxyfen, spiroxamine, sulfur, tebuconazole, tetrconazole, thiabendazole, thifluzamide, thiophanate-methyl, thiram, tiadinil, triadimefon, triadimenol, tricyclazole, trifloxystrobin, triticonazole, validamycin, vinclozin. 
     Biological agents:  Bacillus thuringiensis  ssp  aizawai, kurstaki, Bacillus thuringiensis  delta endotoxin, baculovirus, entomopathogenic bacteria, virus and fungi. 
     Bactericides: chlortetracycline, oxytetracycline, streptomycin. 
     Other biological agents: enrofloxacin, febantel, penethamate, moloxicam, cefalexin, kanamycin, pimobendan, clenbuterol, omeprazole, tiamulin, benazepril, pyriprole, cefquinome, florfenicol, buserelin, cefovecin, tulathromycin, ceftiour, carprofen, metaflumizone, praziquarantel, triclabendazole. 
     When used in combination with other active ingredients, the compounds of the invention are preferably used in combination with the following (where “Tx” means a compound of formula (I), and in particular a compound selected from Tables 1 to Table 120, which may result in a synergistic combination with the given active ingredient): imidacloprid+Tx, enrofloxacin+Tx, praziquantel+Tx, pyrantel embonate+Tx, febantel+Tx, penethamate+Tx, moloxicam+Tx, cefalexin+Tx, kanamycin+Tx, pimobendan+Tx, clenbuterol+Tx, fipronil+Tx, ivermectin+Tx, omeprazole+Tx, tiamulin+Tx, benazepril+Tx, milbemycin+Tx, cyromazine+Tx, thiamethoxam+Tx, pyriprole+Tx, deltamethrin+Tx, cefquinome+Tx, florfenicol+Tx, buserelin+Tx, cefovecin+Tx, tulathromycin+Tx, ceftiour+Tx, selamectin+Tx, carprofen+Tx, metaflumizone+Tx, moxidectin+Tx, methoprene (including S-methoprene)+Tx, clorsulon+Tx, pyrantel+Tx, amitraz+Tx, triclabendazole+Tx, avermectin+Tx, abamectin+Tx, emamectin+Tx, eprinomectin+Tx, doramectin+Tx, selamectin+Tx, nemadectin+Tx, albendazole+Tx, cambendazole+Tx, fenbendazole+Tx, flubendazole+Tx, mebendazole+Tx, oxfendazole+Tx, oxibendazole+Tx, parbendazole+Tx, tetramisole+Tx, levamisole+Tx, pyrantel pamoate+Tx, oxantel+Tx, morantel+Tx, triclabendazole+Tx, epsiprantel+Tx, fipronil+Tx, lufenuron+Tx, ecdysone+Tx or tebufenozide+Tx; more preferably, enrofloxacin+Tx, praziquantel+Tx, pyrantel embonate+Tx, febantel+Tx, penethamate+Tx, moloxicam+Tx, cefalexin+Tx, kanamycin+Tx, pimobendan+Tx, clenbuterol+Tx, omeprazole+Tx, tiamulin+Tx, benazepril+Tx, pyriprole+Tx, cefquinome+Tx, florfenicol+Tx, buserelin+Tx, cefovecin+Tx, tulathromycin+Tx, ceftiour+Tx, selamectin+Tx, carprofen+Tx, moxidectin+Tx, clorsulon+Tx, pyrantel+Tx, eprinomectin+Tx, doramectin+Tx, selamectin+Tx, nemadectin+Tx, albendazole+Tx, cambendazole+Tx, fenbendazole+Tx, flubendazole+Tx, mebendazole+Tx, oxfendazole+Tx, oxibendazole+Tx, parbendazole+Tx, tetramisole+Tx, levamisole+Tx, pyrantel pamoate+Tx, oxantel+Tx, morantel+Tx, triclabendazole+Tx, epsiprantel+Tx, lufenuron+Tx or ecdysone+Tx; even more preferably enrofloxacin+Tx, praziquantel+Tx, pyrantel embonate+Tx, febantel+Tx, penethamate+Tx, moloxicam+Tx, cefalexin+Tx, kanamycin+Tx, pimobendan+Tx, clenbuterol+Tx, omeprazole+Tx, tiamulin+Tx, benazepril+Tx, pyriprole+Tx, cefquinome+Tx, florfenicol+Tx, buserelin+Tx, cefovecin+Tx, tulathromycin+Tx, ceftiour+Tx, selamectin+Tx, carprofen+Tx, moxidectin+Tx, clorsulon+Tx or pyrantel+Tx. 
     Examples of ratios include 100:1 to 1:6000, 50:1 to 1:50, 20:1 to 1:20, even more especially from 10:1 to 1:10, 5:1 to 1:5, 2:1 to 1:2, 4:1 to 2:1, 1:1, or 5:1, or 5:2, or 5:3, or 5:4, or 4:1, or 4:2, or 4:3, or 3:1, or 3:2, or 2:1, or 1:5, or 2:5, or 3:5, or 4:5, or 1:4, or 2:4, or 3:4, or 1:3, or 2:3, or 1:2, or 1:600, or 1:300, or 1:150, or 1:35, or 2:35, or 4:35, or 1:75, or 2:75, or 4:75, or 1:6000, or 1:3000, or 1:1500, or 1:350, or 2:350, or 4:350, or 1:750, or 2:750, or 4:750. Those mixing ratios are understood to include, on the one hand, ratios by weight and also, on other hand, molar ratios. 
     Of particular note is a combination where the additional active ingredient has a different site of action from the compound of formula I. In certain instances, a combination with at least one other parasitic invertebrate pest control active ingredient having a similar spectrum of control but a different site of action will be particularly advantageous for resistance management. Thus, a combination product of the invention may comprise a pesticidally effective amount of a compound of formula I and pesticidally effective amount of at least one additional parasitic invertebrate pest control active ingredient having a similar spectrum of control but a different site of action. 
     One skilled in the art recognizes that because in the environment and under physiological conditions salts of chemical compounds are in equilibrium with their corresponding non salt forms, salts share the biological utility of the non salt forms. 
     Thus a wide variety of salts of compounds of the invention (and active ingredients used in combination with the active ingredients of the invention) may be useful for control of invertebrate pests and animal parasites. Salts include acid-addition salts with inorganic or organic acids such as hydrobromic, hydrochloric, nitric, phosphoric, sulfuric, acetic, butyric, fumaric, lactic, maleic, malonic, oxalic, propionic, salicylic, tartaric, 4-toluenesulfonic or valeric acids. The compounds of the invention also include N-oxides. Accordingly, the invention comprises combinations of compounds of the invention including N-oxides and salts thereof and an additional active ingredient including N-oxides and salts thereof. 
     The compositions for use in animal health may also contain formulation auxiliaries and additives, known to those skilled in the art as formulation aids (some of which may be considered to also function as solid diluents, liquid diluents or surfactants). Such formulation auxiliaries and additives may control: pH (buffers), foaming during processing (antifoams such polyorganosiloxanes), sedimentation of active ingredients (suspending agents), viscosity (thixotropic thickeners), in-container microbial growth (antimicrobials), product freezing (antifreezes), color (dyes/pigment dispersions), wash-off (film formers or stickers), evaporation (evaporation retardants), and other formulation attributes. Film formers include, for example, polyvinyl acetates, polyvinyl acetate copolymers, polyvinylpyrrolidone-vinyl acetate copolymer, polyvinyl alcohols, polyvinyl alcohol copolymers and waxes. Examples of formulation auxiliaries and additives include those listed in McCutcheon&#39;s Volume 2: Functional Materials, annual International and North American editions published by McCutcheon&#39;s Division, The Manufacturing Confectioner Publishing Co.; and PCT Publication WO 03/024222. 
     The compounds of the invention can be applied without other adjuvants, but most often application will be of a formulation comprising one or more active ingredients with suitable carriers, diluents, and surfactants and possibly in combination with a food depending on the contemplated end use. One method of application involves spraying a water dispersion or refined oil solution of the combination products. Compositions with spray oils, spray oil concentrations, spreader stickers, adjuvants, other solvents, and synergists such as piperonyl butoxide often enhance compound efficacy. Such sprays can be applied from spray containers such as a can, a bottle or other container, either by means of a pump or by releasing it from a pressurized container, e.g., a pressurized aerosol spray can. Such spray compositions can take various forms, for example, sprays, mists, foams, fumes or fog. Such spray compositions thus can further comprise propellants, foaming agents, etc. as the case may be. Of note is a spray composition comprising a pesticidally effective amount of a compound of the invention and a carrier. One embodiment of such a spray composition comprises a pesticidally effective amount of a compound of the invention and a propellant. Representative propellants include, but are not limited to, methane, ethane, propane, butane, isobutane, butene, pentane, isopentane, neopentane, pentene, hydrofluorocarbons, chlorofluorocarbons, dimethyl ether, and mixtures of the foregoing. Of note is a spray to composition (and a method utilizing such a spray composition dispensed from a spray container) used to control at least one parasitic invertebrate pest selected from the group consisting of mosquitoes, black flies, stable flies, deer flies, horse flies, wasps, yellow jackets, hornets, ticks, spiders, ants, gnats, and the like, including individually or in combinations. 
     The controlling of animal parasites includes controlling external parasites that are parasitic to the surface of the body of the host animal (e.g., shoulders, armpits, abdomen, inner part of the thighs) and internal parasites that are parasitic to the inside of the body of the host animal (e.g., stomach, intestine, lung, veins, under the skin, lymphatic tissue). External parasitic or disease transmitting pests include, for example, chiggers, ticks, lice, mosquitoes, flies, mites and fleas. Internal parasites include heartworms, hookworms and helminths. The compounds of the invention may be particularly suitable for combating external parasitic pests. The compounds of the invention may be suitable for systemic and/or non-systemic control of infestation or infection by parasites on animals. 
     The compounds of the invention may be suitable for combating parasitic invertebrate pests that infest animal subjects including those in the wild, livestock and agricultural working animals. Livestock is the term used to refer (singularly or plurally) to a domesticated animal intentionally reared in an agricultural setting to make produce such as food or fiber, or for its labor; examples of livestock include cattle, sheep, goats, horses, pigs, donkeys, camels, buffalo, rabbits, hens, turkeys, ducks and geese (e.g., raised for meat, milk, butter, eggs, fur, leather, feathers and/or wool). By combating parasites, fatalities and performance reduction (in terms of meat, milk, wool, skins, eggs, etc.) are reduced, so that applying the compounds of the invention allows more economic and simple husbandry of animals. 
     The compounds of the invention may be suitable for combating parasitic invertebrate pests that infest companion animals and pets (e.g., dogs, cats, pet birds and aquarium fish), research and experimental animals (e.g., hamsters, guinea pigs, rats and mice), as well as animals raised for/in zoos, wild habitats and/or circuses. 
     In an embodiment of this invention, the animal is preferably a vertebrate, and more preferably a mammal, avian or fish. In a particular embodiment, the animal subject is a mammal (including great apes, such as humans). Other mammalian subjects include primates (e.g., monkeys), bovine (e.g., cattle or dairy cows), porcine (e.g., hogs or pigs), ovine (e.g., goats or sheep), equine (e.g., horses), canine (e.g., dogs), feline (e.g., house cats), camels, deer, donkeys, buffalos, antelopes, rabbits, and rodents (e.g., guinea pigs, squirrels, rats, mice, gerbils, and hamsters). Avians include Anatidae (swans, ducks and geese), Columbidae (e.g., doves and pigeons), Phasianidae (e.g., partridges, grouse and turkeys), Thesienidae (e.g., domestic chickens), Psittacines (e.g., parakeets, macaws, and parrots), game birds, and ratites (e.g., ostriches). 
     Birds treated or protected by the compounds of the invention can be associated with either commercial or noncommercial aviculture. These include Anatidae, such as swans, geese, and ducks, Columbidae, such as doves and domestic pigeons, Phasianidae, such as partridge, grouse and turkeys, Thesienidae, such as domestic chickens, and Psittacines, such as parakeets, macaws and parrots raised for the pet or collector market, among others. 
     For purposes of the present invention, the term “fish” is understood to include without limitation, the Teleosti grouping of fish, i.e., teleosts. Both the Salmoniformes order (which includes the Salmonidae family) and the Perciformes order (which includes the Centrarchidae family) are contained within the Teleosti grouping. Examples of potential fish recipients include the Salmonidae, Serranidae, Sparidae, Cichlidae, and Centrarchidae, among others. 
     Other animals are also contemplated to benefit from the inventive methods, including marsupials (such as kangaroos), reptiles (such as farmed turtles), and other economically important domestic animals for which the inventive methods are safe and effective in treating or preventing parasite infection or infestation. 
     Examples of parasitic invertebrate pests controlled by administering a pesticidally effective amount of the compounds of the invention to an animal to be protected include ectoparasites (arthropods, acarines, etc.) and endoparasites (helminths, e.g., nematodes, trematodes, cestodes, acanthocephalans, etc.). 
     The disease or group of diseases described generally as helminthiasis is due to infection of an animal host with parasitic worms known as helminths. The term ‘helminths’ is meant to include nematodes, trematodes, cestodes and acanthocephalans. Helminthiasis is a prevalent and serious economic problem with domesticated animals such as swine, sheep, horses, cattle, goats, dogs, cats and poultry. 
     Among the helminths, the group of worms described as nematodes causes widespread and at times serious infection in various species of animals. 
     Nematodes that are contemplated to be treated by the compounds of the invention include, without limitation, the following genera:  Acanthocheilonema, Aelurostrongylus, Ancylostoma, Angiostrongylus, Ascaridia, Ascaris, Brugia, Bunostomum, Capillaria, Chabertia, Cooperia, Crenosoma, Dictyocaulus, Dioctophyme, Dipetalonema, Diphyllobothrium, Dirofilaria, Dracunculus, Enterobius, Filaroides, Haemonchus, Heterakis, Lagochilascaris, Loa, Mansonella, Muellerius, Necator, Nematodirus, Oesophagostomum, Ostertagia, Oxyuris, Parafilaria, Parascaris, Physaloptera, Protostrongylus, Setaria, Spirocerca, Stephanofilaria, Strongyloides, Strongylus, Thelazia, Toxascaris, Toxocara, Trichinella, Trichonema, Trichostrongylus, Trichuris, Uncinaria  and  Wuchereria.    
     Of the above, the most common genera of nematodes infecting the animals referred to above are  Haemonchus, Trichostrongylus, Ostertagia, Nematodirus, Cooperia, Ascaris, Bunostomum, Oesophagostomum, Chabertia, Trichuris, Strongylus, Trichonema, Dictyocaulus, Capillaria, Heterakis, Toxocara, Ascaridia, Oxyuris, Ancylostoma, Uncinaria, Toxascaris  and  Parascaris . Certain of these, such as  Nematodirus, Cooperia  and  Oesophagostomum  attack primarily the intestinal tract while others, such as  Haemonchus  and  Ostertagia , are more prevalent in the stomach while others such as  Dictyocaulus  are found in the lungs. Still other parasites may be located in other tissues such as the heart and blood vessels, subcutaneous and lymphatic tissue and the like. 
     Trematodes that are contemplated to be treated by the invention and by the inventive methods include, without limitation, the following genera:  Alaria, Fasciola, Nanophyetus, Opisthorchis, Paragonimus  and  Schistosoma.    
     Cestodes that are contemplated to be treated by the invention and by the inventive methods include, without limitation, the following genera:  Diphyllobothrium, Diplydium, Spirometra  and  Taenia.    
     The most common genera of parasites of the gastrointestinal tract of humans are 
       Ancylostoma, Necator, Ascaris, Strongy hides, Trichinella, Capillaria, Trichuris  and  Enterobius . Other medically important genera of parasites which are found in the blood or other tissues and organs outside the gastrointestinal tract are the filarial worms such as  Wuchereria, Brugia, Onchocerca  and  Loa , as well as  Dracunculus  and extra intestinal stages of the intestinal worms  Strongyloides  and  Trichinella.    
     Numerous other helminth genera and species are known to the art, and are also contemplated to be treated by the compounds of the invention. These are enumerated in great detail in Textbook of Veterinary Clinical Parasitology, Volume 1, Helminths, E. J. L. Soulsby, F. A. Davis Co., Philadelphia, Pa.; Helminths, Arthropods and Protozoa, (6 th  Edition of Monnig&#39;s Veterinary Helminthology and Entomology), E. J. L. Soulsby, Williams and Wilkins Co., Baltimore, Md. 
     The compounds of the invention may be effective against a number of animal ectoparasites (e.g., arthropod ectoparasites of mammals and birds). 
     Insect and acarine pests include, e.g., biting insects such as flies and mosquitoes, mites, ticks, lice, fleas, true bugs, parasitic maggots, and the like. 
     Adult flies include, e.g., the horn fly or  Haematobia irritans , the horse fly or  Tabanus  spp., the stable fly or  Stomoxys calcitrans , the black fly or  Simulium  spp., the deer fly or  Chrysops  spp., the louse fly or  Melophagus ovinus , and the tsetse fly or  Glossina  spp. Parasitic fly maggots include, e.g., the bot fly ( Oestrus ovis  and  Cuterebra  spp.), the blow fly or  Phaenicia  spp., the screwworm or  Cochliomyia hominivorax , the cattle grub or  Hypoderma  spp., the fleeceworm and the  Gastrophilus  of horses. Mosquitoes include, for example,  Culex  spp.,  Anopheles  spp. and  Aedes  spp. 
     Mites include  Mesostigmalphatalpha  spp., e.g.  mesostigmatids  such as the chicken mite,  Dermalphanyssus galphallinalphae ; itch or scab mites such as  Sarcoptidae  spp. for example,  Salpharcoptes scalphabiei ; mange mites such as  Psoroptidae  spp. including  Chorioptes bovis  and  Psoroptes ovis ; chiggers, e.g.  Trombiculidae  spp. for example the North American chigger,  Trombicula alfreddugesi.    
     Ticks include, e.g., soft-bodied ticks including  Argasidae  spp. for example  Argalphas  spp. and  Ornithodoros  spp.; hard-bodied ticks including  Ixodidae  spp., for example  Rhipicephalphalus sanguineus, Dermacentor variabilis, Dermacentor andersoni, Amblyomma americanum, Ixodes scapularis  and other  Rhipicephalus  spp. (including the former  Boophilus  genera). 
     Lice include, e.g., sucking lice, e.g.,  Menopon  spp. 
     and  Bovicola  spp.; biting lice, e.g.,  Haematopinus  spp.,  Linognathus  spp. and  Solenopotes  spp. 
     Fleas include, e.g.,  Ctenocephalides  spp., such as dog flea ( Ctenocephalides canis ) and cat flea ( Ctenocephalides fells );  Xenopsylla  spp. such as oriental rat flea ( Xenopsylla cheopis ); and  Pulex  spp. such as human flea ( Pulex irritans ). 
     True bugs include, e.g.,  Cimicidae  or e.g., the common bed bug ( Cimex lectularius );  Triatominae  spp. including triatomid bugs also known as kissing bugs; for example  Rhodnius prolixus  and  Triatoma  spp. 
     Generally, flies, fleas, lice, mosquitoes, gnats, mites, ticks and helminths cause tremendous losses to the livestock and companion animal sectors. Arthropod parasites also are a nuisance to humans and can vector disease-causing organisms in humans and animals. 
     Numerous other parasitic invertebrate pests are known to the art, and are also contemplated to be treated by the compounds of the invention. These are enumerated in great detail in Medical and Veterinary Entomology, D. S. Kettle, John Wiley AND Sons, New York and Toronto; Control of Arthropod Pests of Livestock: A Review of Technology, R. O. Drummand, J. E. George, and S. E. Kunz, CRC Press, Boca Raton, Fla. 
     The present invention also provides a method for controlling pests (such as mosquitoes and other disease vectors; see also http://www.who.int/malaria/vector_control/irs/en/). In one embodiment, the method for controlling pests comprises applying the compositions of the invention to the target pests, to their locus or to a surface or substrate by brushing, rolling, spraying, spreading or dipping. By way of example, an IRS (indoor residual spraying) application of a surface such as a wall, ceiling or floor surface is contemplated by the method of the invention. In another embodiment, it is contemplated to apply such compositions to a substrate such as non-woven or a fabric material in the form of (or which can be used in the manufacture of) netting, clothing, bedding, curtains and tents. 
     In one embodiment, the method for controlling such pests comprises applying a pesticidally effective amount of the compositions of the invention to the target pests, to their locus, or to a surface or substrate so as to provide effective residual pesticidal activity on the surface or substrate. Such application may be made by brushing, rolling, spraying, spreading or dipping the pesticidal composition of the invention. By way of example, an IRS application of a surface such as a wall, ceiling or floor surface is contemplated by the method of the invention so as to provide effective residual pesticidal activity on the surface. In another embodiment, it is contemplated to apply such compositions for residual control of pests on a substrate such as a fabric material in the form of (or which can be used in the manufacture of) netting, clothing, bedding, curtains and tents. 
     Substrates including non-woven, fabrics or netting to be treated may be made of natural fibres such as cotton, raffia, jute, flax, sisal, hessian, or wool, or synthetic fibres such as polyamide, polyester, polypropylene, polyacrylonitrile or the like. The polyesters are particularly suitable. The methods of textile treatment are know, e.g. from Handbuch Textilveredlung: Band 1: Ausrüstung, Band 2: Farbgebung, Band 3: Beschichtung, Band 4: Umwelttechnik; Verlag: Deutscher Fachverlag; Auflage: 15., überarbeitete Ausgabe (17. April 2006); ISBN-10: 3866410123; ISBN-13: 978-3866410121, see especially Band 1: Ausrüstung pages 27-198, more preferably on page 118; or WO2008151984 or WO2003034823 or U.S. Pat. No. 5,631,072 or WO200564072 or WO2006128870 or EP1724392 or WO2005064072 or WO2005113886 or WO2007090739. 
     The compounds of the invention may also be effective against ectoparasites including: flies such as  Haematobia  (Lyperosia) irritans (horn fly),  Simulium  spp. (blackfly),  Glossina  spp. (tsetse flies),  Hydrotaea irritans  (head fly),  Musca autumnalis  (face fly),  Musca domestica  (house fly),  Morellia simplex  (sweat fly),  Tabanus  spp. (horse fly),  Hypoderma bovis, Hypoderma lineatum, Lucilia sericata, Lucilia cuprina  (green blowfly),  Calliphora  spp. (blowfly),  Protophormia  spp.,  Oestrus ovis  (nasal botfly),  Culicoides  spp. (midges),  Hippobosca equine, Gastrophilus intestinalis, Gastrophilus haemorrhoidalis  and  Gastrophilus nasalis ; lice such as  Bovicola  (Damalinia)  bovis, Bovicola equi, Haematopinus asini, Felicola subrostratus, Heterodoxus spiniger, Lignonathus setosus  and  Trichodectes canis ; keds such as  Melophagus ovinus ; and mites such as  Psoroptes  spp.,  Sarcoptes scabei, Chorioptes bovis, Demodex equi, Cheyletiella  spp.,  Notoedres cati, Trombicula  spp. and  Otodectes cyanotis  (ear mites). 
     Treatments of the invention are by conventional means such as by enteral administration in the form of, for example, tablets, capsules, drinks, drenching preparations, granulates, pastes, boli, feed-through procedures, or suppositories; or by parenteral administration, such as, for example, by injection (including intramuscular, subcutaneous, intravenous, intraperitoneal) or implants; or by nasal administration. 
     When compounds of the invention are applied in combination with an additional biologically active ingredient, they may be administered separately e.g. as separate compositions. In this case, the biologically active ingredients may be administered simultaneously or sequentially. Alternatively, the biologically active ingredients may be components of one composition. 
     The compounds of the invention may be administered in a controlled release form, for example in subcutaneous or orally adminstered slow release formulations. 
     Typically a parasiticidal composition according to the present invention comprises a compound of the invention, optionally in combination with an additional biologically active ingredient, or N-oxides or salts thereof, with one or more pharmaceutically or veterinarily acceptable carriers comprising excipients and auxiliaries selected with regard to the intended to route of administration (e.g., oral or parenteral administration such as injection) and in accordance with standard practice. In addition, a suitable carrier is selected on the basis of compatibility with the one or more active ingredients in the composition, including such considerations as stability relative to pH and moisture content. Therefore of note are compounds of the invention for protecting an animal from an invertebrate parasitic pest comprising a parasitically effective amount of a compound of the invention, optionally in combination with an additional biologically active ingredient and at least one carrier. 
     For parenteral administration including intravenous, intramuscular and subcutaneous injection, the compounds of the invention can be formulated in suspension, solution or emulsion in oily or aqueous vehicles, and may contain adjuncts such as suspending, stabilizing and/or dispersing agents. 
     The compounds of the invention may also be formulated for bolus injection or continuous infusion. Pharmaceutical compositions for injection include aqueous solutions of water-soluble forms of active ingredients (e.g., a salt of an active compound), preferably in physiologically compatible buffers containing other excipients or auxiliaries as are known in the art of pharmaceutical formulation. Additionally, suspensions of the active compounds may be prepared in a lipophilic vehicle. Suitable lipophilic vehicles include fatty oils such as sesame oil, synthetic fatty acid esters such as ethyl oleate and triglycerides, or materials such as liposomes. 
     Aqueous injection suspensions may contain substances that increase the viscosity of the suspension, such as sodium carboxymethyl cellulose, sorbitol, or dextran. Formulations for injection may be presented in unit dosage form, e.g., in ampoules or in multi-dose containers. Alternatively, the active ingredient may be in powder form for constitution with a suitable vehicle, e.g., sterile, pyrogen-free water, before use. 
     In addition to the formulations described supra, the compounds of the invention may also be formulated as a depot preparation. Such long acting formulations may be administered by implantation (for example, subcutaneously or intramuscularly) or by intramuscular or subcutaneous injection. 
     The compounds of the invention may be formulated for this route of administration with suitable polymeric or hydrophobic materials (for instance, in an emulsion with a pharmacologically acceptable oil), with ion exchange resins, or as a sparingly soluble derivative such as, without limitation, a sparingly soluble salt. 
     For administration by inhalation, the compounds of the invention can be delivered in the form of an aerosol spray using a pressurized pack or a nebulizer and a suitable propellant, e.g., without limitation, dichlorodifluoromethane, trichlorofluoromethane, dichlorotetrafluoroethane or carbon dioxide. In the case of a pressurized aerosol, the dosage unit may be controlled by providing a valve to deliver a metered amount. 
     Capsules and cartridges of, for example, gelatin for use in an inhaler or insufflator may be formulated containing a powder mix of the compound and a suitable powder base such as lactose or starch. 
     The compounds of the invention may have favourable pharmacokinetic and pharmacodynamic properties providing systemic availability from oral administration and ingestion. Therefore after ingestion by the animal to be protected, parasiticidally effective concentrations of a compound of the invention in the bloodstream may protect the treated animal from blood-sucking pests such as fleas, ticks and lice. Therefore of note is a composition for protecting an animal from an invertebrate parasite pest in a form for oral administration (i.e. comprising, in addition to a parasiticidally effective amount of a compound of the invention, one or more carriers selected from binders and fillers suitable for oral administration and feed concentrate carriers). 
     For oral administration in the form of solutions (the most readily available form for absorption), emulsions, suspensions, pastes, gels, capsules, tablets, boluses, powders, granules, rumen-retention and feed/water/lick blocks, the compounds of the invention can be formulated with binders/fillers known in the art to be suitable for oral administration compositions, such as sugars and sugar derivatives (e.g., lactose, sucrose, mannitol, sorbitol), starch (e.g., maize starch, wheat starch, rice starch, potato starch), cellulose and derivatives (e.g., methylcellulose, carboxymethylcellulose, ethylhydroxycellulose), protein derivatives (e.g., zein, gelatin), and synthetic polymers (e.g., polyvinyl alcohol, polyvinylpyrrolidone). If desired, lubricants (e.g., magnesium stearate), disintegrating agents (e.g., cross-linked polyvinylpyrrolidinone, agar, alginic acid) and dyes or pigments can be added. Pastes and gels often also contain adhesives (e.g., acacia, alginic acid, bentonite, cellulose, xanthan gum, colloidal magnesium aluminum silicate) to aid in keeping the composition in contact with the oral cavity and not being easily ejected. 
     In one embodiment a composition of the present invention is formulated into a chewable and/or edible product (e.g., a chewable treat or edible tablet). Such a product would ideally have a taste, texture and/or aroma favored by the animal to be protected so as to facilitate oral administration of the compounds of the invention. 
     If the parasiticidal compositions are in the form of feed concentrates, the carrier is typically selected from high-performance feed, feed cereals or protein concentrates. 
     Such feed concentrate-containing compositions can, in addition to the parasiticidal active ingredients, comprise additives promoting animal health or growth, improving quality of meat from animals for slaughter or otherwise useful to animal husbandry. 
     These additives can include, for example, vitamins, antibiotics, chemotherapeutics, bacteriostats, fungistats, coccidiostats and hormones. 
     The compound of the invention may also be formulated in rectal compositions such as suppositories or retention enemas, using, e.g., conventional suppository bases such as cocoa butter or other glycerides. 
     The formulations for the method of this invention may include an antioxidant, such asBHT (butylated hydroxytoluene). The antioxidant is generally present in amounts of at 0.1-5 percent (wt/vol). Some of the formulations require a solubilizer, such as oleic acid, to dissolve the active agent, particularly if spinosad is included. Common spreading agents used in these pour-on formulations include isopropyl myristate, isopropyl palmitate, caprylic/capric acid esters of saturated C 12 -C 18  fatty alcohols, oleic acid, oleyl ester, ethyl oleate, triglycerides, silicone oils and dipropylene glycol methyl ether. The pour-on formulations for the method of this invention are prepared according to known techniques. Where the pour-on is a solution, the parasiticide/insecticide is mixed with the carrier or vehicle, using heat and stirring if required. Auxiliary or additional ingredients can be added to the mixture of active agent and carrier, or they can be mixed with the active agent prior to the addition of the carrier. Pour-on formulations in the form of emulsions or suspensions are similarly prepared using known techniques. 
     Other delivery systems for relatively hydrophobic pharmaceutical compounds may be employed. Liposomes and emulsions are well-known examples of delivery vehicles or carriers for hydrophobic drugs. In addition, organic solvents such as dimethylsulfoxide may be used, if needed. 
     The rate of application required for effective parasitic invertebrate pest control (e.g. “pesticidally effective amount”) will depend on such factors as the species of parasitic invertebrate pest to be controlled, the pest&#39;s life cycle, life stage, its size, location, time of year, host crop or animal, feeding behavior, mating behavior, ambient moisture, temperature, and the like. One skilled in the art can easily determine the pesticidally effective amount necessary for the desired level of parasitic invertebrate pest control. 
     In general for veterinary use, the compounds of the invention are administered in a pesticidally effective amount to an animal, particularly a homeothermic animal, to be protected from parasitic invertebrate pests. 
     A pesticidally effective amount is the amount of active ingredient needed to achieve an observable effect diminishing the occurrence or activity of the target parasitic invertebrate pest. One skilled in the art will appreciate that the pesticidally effective dose can vary for the various compounds and compositions useful for the method of the present invention, the desired pesticidal effect and duration, the target parasitic invertebrate pest species, the animal to be protected, the mode of application and the like, and the amount needed to achieve a particular result can be determined through simple experimentation. 
     For oral or parenteral administration to animals, a dose of the compositions of the present invention administered at suitable intervals typically ranges from about 0.01 mg/kg to about 100 mg/kg, and preferably from about 0.01 mg/kg to about 30 mg/kg of animal body weight. 
     Suitable intervals for the administration of the compositions of the present invention to animals range from about daily to about yearly. Of note are administration intervals ranging from about weekly to about once every 6 months. Of particular note are monthly administration intervals (i.e. administering the compounds to the animal once every month). 
     The present invention also provides a method for controlling pests (such as mosquitoes and other disease vectors). In one embodiment, the method for controlling pests comprises applying the compositions of the invention to the target pests, to their locus or to a surface or substrate by brushing, rolling, spraying, spreading or dipping. By way of example, an IRS application of a surface such as a wall, ceiling or floor surface is contemplated by the method of the invention. In another embodiment, it is contemplated to apply such compositions to a substrate such as non-woven or a fabric material in the form of (or which can be used in the manufacture of) netting, clothing, bedding, curtains and tents. 
     In one embodiment, the method for controlling such pests comprises applying a pesticidally effective amount of the compositions of the invention to the target pests, to their locus, or to a surface or substrate so as to provide effective residual pesticidal activity on the surface or substrate. Such application may be made by brushing, rolling, spraying, spreading or dipping the pesticidal composition of the invention. By way of example, an IRS application of a surface such as a wall, ceiling or floor surface is contemplated by the method of the invention so as to provide effective residual pesticidal activity on the surface. In another embodiment, it is contemplated to apply such compositions for residual control of pests on a substrate such as a fabric material in the form of (or which can be used in the manufacture of) netting, clothing, bedding, curtains and tents. 
     Substrates including non-woven, fabrics or netting to be treated may be made of natural fibres such as cotton, raffia, jute, flax, sisal, hessian, or wool, or synthetic fibres such as polyamide, polyester, polypropylene, polyacrylonitrile or the like. The polyesters are particularly suitable. The methods of textile treatment are know, e.g. from Handbuch Textilveredlung: Band 1: Ausrüstung, Band 2: Farbgebung, Band 3: Beschichtung, Band 4: Umwelttechnik; Verlag: Deutscher Fachverlag; Auflage: 15., überarbeitete Ausgabe (17. April 2006); ISBN-10: 3866410123; ISBN-13: 978-3866410121, see especially Band 1: Ausrüstung pages 27-198, more preferably on page 118; or WO2008151984 or WO2003034823 or U.S. Pat. No. 5,631,072 or WO200564072 or WO2006128870 or EP1724392 or WO2005064072 or WO2005113886 or WO2007090739. 
     The term “plant” as used herein includes seedlings, bushes and trees. The term “crops” is to be understood as including also crop plants which have been so transformed by the use of recombinant DNA techniques that they are capable of synthesising one or more selectively acting toxins, such as are known, for example, from toxin-producing bacteria, especially those of the genus  Bacillus.    
     Toxins that can be expressed by such transgenic plants include, for example, insecticidal proteins, from  Bacillus cereus  or  Bacillus popilliae ; or insecticidal proteins from  Bacillus thuringiensis , such as δ-endotoxins, e.g. Cry1Ab, Cry1Ac, Cry1F, Cry1Fa2, Cry2Ab, Cry3A, Cry3Bb1 or Cry9C, or vegetative insecticidal proteins (Vip), e.g. Vip1, Vip2, Vip3 or Vip3A; or insecticidal proteins of bacteria colonising nematodes, for example  Photorhabdus  spp. or  Xenorhabdus  spp., such as  Photorhabdus luminescens, Xenorhabdus nematophilus ; toxins produced by animals, such as scorpion toxins, arachnid toxins, wasp toxins and other insect-specific neurotoxins; toxins produced by fungi, such as Streptomycetes toxins, plant lectins, such as pea lectins, barley lectins or snowdrop lectins; agglutinins; proteinase inhibitors, such as trypsin inhibitors, serine protease inhibitors, patatin, cystatin, papain inhibitors; ribosome-inactivating proteins (RIP), such as ricin, maize-RIP, abrin, luffin, saporin or bryodin; steroid metabolism enzymes, such as 3-hydroxysteroidoxidase, ecdysteroid-UDP-glycosyl-transferase, cholesterol oxidases, ecdysone inhibitors, HMG-COA-reductase, ion channel blockers, such as blockers of sodium or calcium channels, juvenile hormone esterase, diuretic hormone receptors, stilbene synthase, bibenzyl synthase, chitinases and glucanases. 
     In the context of the present invention there are to be understood by δ-endotoxins, for example Cry1Ab, Cry1Ac, Cry1F, Cry1Fa2, Cry2Ab, Cry3A, Cry3Bb1 or Cry9C, or vegetative insecticidal proteins (Vip), for example Vip1, Vip2, Vip3 or Vip3A, expressly also hybrid toxins, truncated toxins and modified toxins. Hybrid toxins are produced recombinantly by a new combination of different domains of those proteins (see, for example, WO 02/15701). Truncated toxins, for example a truncated Cry1Ab, are known. In the case of modified toxins, one or more amino acids of the naturally occurring toxin are replaced. In such amino acid replacements, preferably non-naturally present protease recognition sequences are inserted into the toxin, such as, for example, in the case of Cry3A055, a cathepsin-G-recognition sequence is inserted into a Cry3A toxin (see WO 03/018810). 
     Examples of such toxins or transgenic plants capable of synthesising such toxins are disclosed, for example, in EP-A-0 374 753, WO 93/07278, WO 95/34656, EP-A-0 427 529, EP-A-451 878 and WO 03/052073. 
     The processes for the preparation of such transgenic plants are generally known to the person skilled in the art and are described, for example, in the publications mentioned above. Cry1-type deoxyribonucleic acids and their preparation are known, for example, from WO 95/34656, EP-A-0 367 474, EP-A-0 401 979 and WO 90/13651. 
     The toxin contained in the transgenic plants imparts to the plants tolerance to harmful insects. Such insects can occur in any taxonomic group of insects, but are especially commonly found in the beetles (Coleoptera), two-winged insects (Diptera) and butterflies (Lepidoptera). 
     Transgenic plants containing one or more genes that code for an insecticidal resistance and express one or more toxins are known and some of them are commercially available. Examples of such plants are: YieldGard® (maize variety that expresses a Cry1Ab toxin); YieldGard Rootworm® (maize variety that expresses a Cry3Bb 1 toxin); YieldGard Plus® (maize variety that expresses a Cry1Ab and a Cry3Bb1 toxin); Starlink® (maize variety that expresses a Cry9C toxin); Herculex I® (maize variety that expresses a Cry1Fa2 toxin and the enzyme phosphinothricine N-acetyltransferase (PAT) to achieve tolerance to the herbicide glufosinate ammonium); NuCOTN 33B® (cotton variety that expresses a Cry1Ac toxin); Bollgard I® (cotton variety that expresses a Cry1Ac toxin); Bollgard II® (cotton variety that expresses a Cry1Ac and a Cry2Ab toxin); VipCot® (cotton variety that expresses a Vip3A and a Cry1Ab toxin); NewLeaf® (potato variety that expresses a Cry3A toxin); NatureGard ®, Agrisure® GT Advantage (GA21 glyphosate-tolerant trait), Agrisure® CB Advantage (Bt11 corn borer (CB) trait) and Protecta®. 
     Further examples of such transgenic crops are: 
     1. Btl1 Maize from Syngenta Seeds SAS, Chemin de l&#39;Hobit 27, F-31 790 St. Sauveur, France, registration number C/FR/96/05/10. Genetically modified  Zea mays  which has been rendered resistant to attack by the European corn borer ( Ostrinia nubilalis  and  Sesamia nonagrioides ) by transgenic expression of a truncated Cry1Ab toxin. Bt11 maize also transgenically expresses the enzyme PAT to achieve tolerance to the herbicide glufosinate ammonium.
 
2. Bt176 Maize from Syngenta Seeds SAS, Chemin de l&#39;Hobit 27, F-31 790 St. Sauveur, France, registration number C/FR/96/05/10. Genetically modified  Zea mays  which has been rendered resistant to attack by the European corn borer ( Ostrinia nubilalis  and  Sesamia nonagrioides ) by transgenic expression of a Cry1Ab toxin. Bt176 maize also transgenically expresses the enzyme PAT to achieve tolerance to the herbicide glufosinate ammonium.
 
3. MIR604 Maize from Syngenta Seeds SAS, Chemin de l&#39;Hobit 27, F-31 790 St. Sauveur, France, registration number C/FR/96/05/10. Maize which has been rendered insect-resistant by transgenic expression of a modified Cry3A toxin. This toxin is Cry3A055 modified by insertion of a cathepsin-G-protease recognition sequence. The preparation of such transgenic maize plants is described in WO 03/018810.
 
4. MON 863 Maize from Monsanto Europe S.A. 270-272 Avenue de Tervuren, B-1150 Brussels, Belgium, registration number C/DE/02/9. MON 863 expresses a Cry3Bb1 toxin and has resistance to certain Coleoptera insects.
 
5. IPC 531 Cotton from Monsanto Europe S.A. 270-272 Avenue de Tervuren, B-1150 Brussels, Belgium, registration number C/ES/96/02.
 
6. 1507 Maize from Pioneer Overseas Corporation, Avenue Tedesco, 7 B-1160 Brussels, Belgium, registration number C/NL/00/10. Genetically modified maize for the expression of the protein Cry1F for achieving resistance to certain Lepidoptera insects and of the PAT protein for achieving tolerance to the herbicide glufosinate ammonium.
 
7. NK603×MON 810 Maize from Monsanto Europe S.A. 270-272 Avenue de Tervuren, B-1150 Brussels, Belgium, registration number C/GB/02/M3/03. Consists of conventionally bred hybrid maize varieties by crossing the genetically modified varieties NK603 and MON 810. NK603×MON 810 Maize transgenically expresses the protein CP4 EPSPS, obtained from  Agrobacterium  sp. strain CP4, which imparts tolerance to the herbicide Roundup® (contains glyphosate), and also a Cry1Ab toxin obtained from  Bacillus thuringiensis  subsp.  kurstaki  which brings about tolerance to certain Lepidoptera, include the European corn borer.
 
     Crops are also to be understood as being those which have been rendered resistant to harmful insects by genetic engineering methods, for example Bt maize (resistant to European corn borer), Bt cotton (resistant to cotton boll weevil) and also Bt potatoes (resistant to Colorado beetle). Examples of Bt maize are the Bt 176 maize hybrids of NK® (Syngenta Seeds). Examples of transgenic plants comprising one or more genes that code for an insecticidal resistance and express one or more toxins are KnockOut® (maize), Yield Gard® (maize), NuCOTIN33B® (cotton), Bollgard® (cotton), NewLeaf® (potatoes), NatureGard® and Protexcta®. 
     Plant crops or seed material thereof can be both resistant to herbicides and, at the same time, resistant to insect feeding (“stacked” transgenic events). For example, seed can have the ability to express an insecticidal Cry3 protein while at the same time being tolerant to glyphosate. 
     Crops are also to be understood as being those which are obtained by conventional methods of breeding or genetic engineering and contain so-called output traits (e.g. improved storage stability, higher nutritional value and improved flavour). 
     In order to apply a compound of formula (I) as an insecticide, acaricide, nematicide or molluscicide to a pest, a locus of pest, or to a plant susceptible to attack by a pest, a compound of formula (I) is usually formulated into a composition which includes, in addition to the compound of formula (I), a suitable inert diluent or carrier and, optionally, a surface active agent (SFA). SFAs are chemicals which are able to modify the properties of an interface (for example, liquid/solid, liquid/air or liquid/liquid interfaces) by lowering the interfacial tension and thereby leading to changes in other properties (for example dispersion, emulsification and wetting). It is preferred that all compositions (both solid and liquid formulations) comprise, by weight, 0.0001 to 95%, more preferably 1 to 85%, for example 5 to 60%, of a compound of formula (I). The composition is generally used for the control of pests such that a compound of formula (I) is applied at a rate of from 0.1 g to 10 kg per hectare, preferably from 1 g to 6 kg per hectare, more preferably from 1 g to 1 kg per hectare. 
     When used in a seed dressing, a compound of formula (I) is used at a rate of 0.0001 g to 10 g (for example 0.001 g or 0.05 g), preferably 0.005 g to 10 g, more preferably 0.005 g to 4 g, per kilogram of seed. 
     In another aspect the present invention provides an insecticidal, acaricidal, nematicidal or molluscicidal composition comprising an insecticidally, acaricidally, nematicidally or molluscicidally effective amount of a compound of formula (I) and a suitable carrier or diluent therefor. The composition is preferably an insecticidal, acaricidal, nematicidal or molluscicidal composition. 
     The compositions can be chosen from a number of formulation types, including dustable powders (DP), soluble powders (SP), water soluble granules (SG), water dispersible granules (WG), wettable powders (WP), granules (GR) (slow or fast release), soluble concentrates (SL), oil miscible liquids (OL), ultra low volume liquids (UL), emulsifiable concentrates (EC), dispersible concentrates (DC), emulsions (both oil in water (EW) and water in oil (EO)), micro-emulsions (ME), suspension concentrates (SC), aerosols, fogging/smoke formulations, capsule suspensions (CS) and seed treatment formulations. The formulation type chosen in any instance will depend upon the particular purpose envisaged and the physical, chemical and biological properties of the compound of formula (I). 
     Dustable powders (DP) may be prepared by mixing a compound of formula (I) with one or more solid diluents (for example natural clays, kaolin, pyrophyllite, bentonite, alumina, montmorillonite, kieselguhr, chalk, diatomaceous earths, calcium phosphates, calcium and magnesium carbonates, sulfur, lime, flours, talc and other organic and inorganic solid carriers) and mechanically grinding the mixture to a fine powder. 
     Soluble powders (SP) may be prepared by mixing a compound of formula (I) with one or more water-soluble inorganic salts (such as sodium bicarbonate, sodium carbonate or magnesium sulfate) or one or more water-soluble organic solids (such as a polysaccharide) and, optionally, one or more wetting agents, one or more dispersing agents or a mixture of said agents to improve water dispersibility/solubility. The mixture is then ground to a fine powder. Similar compositions may also be granulated to form water soluble granules (SG). 
     Wettable powders (WP) may be prepared by mixing a compound of formula (I) with one or more solid diluents or carriers, one or more wetting agents and, preferably, one or more dispersing agents and, optionally, one or more suspending agents to facilitate the dispersion in liquids. The mixture is then ground to a fine powder. Similar compositions may also be granulated to form water dispersible granules (WG). 
     Granules (GR) may be formed either by granulating a mixture of a compound of formula (I) and one or more powdered solid diluents or carriers, or from pre-formed blank granules by absorbing a compound of formula (I) (or a solution thereof, in a suitable agent) in a porous granular material (such as pumice, attapulgite clays, fuller&#39;s earth, kieselguhr, diatomaceous earths or ground corn cobs) or by adsorbing a compound of formula (I) (or a solution thereof, in a suitable agent) on to a hard core material (such as sands, silicates, mineral carbonates, sulfates or phosphates) and drying if necessary. Agents which are commonly used to aid absorption or adsorption include solvents (such as aliphatic and aromatic petroleum solvents, alcohols, ethers, ketones and esters) and sticking agents (such as polyvinyl acetates, polyvinyl alcohols, dextrins, sugars and vegetable oils). One or more other additives may also be included in granules (for example an emulsifying agent, wetting agent or dispersing agent). 
     Dispersible Concentrates (DC) may be prepared by dissolving a compound of formula (I) in water or an organic solvent, such as a ketone, alcohol or glycol ether. These solutions may contain a surface active agent (for example to improve water dilution or prevent crystallisation in a spray tank). 
     Emulsifiable concentrates (EC) or oil-in-water emulsions (EW) may be prepared by dissolving a compound of formula (I) in an organic solvent (optionally containing one or more wetting agents, one or more emulsifying agents or a mixture of said agents). Suitable organic solvents for use in ECs include aromatic hydrocarbons (such as alkylbenzenes or alkylnaphthalenes, exemplified by SOLVESSO 100, SOLVESSO 150 and SOLVESSO 200; SOLVESSO is a Registered Trade Mark), ketones (such as cyclohexanone or methylcyclohexanone) and alcohols (such as benzyl alcohol, furfuryl alcohol or butanol), N-alkylpyrrolidones (such as N-methylpyrrolidone or N-octylpyrrolidone), dimethyl amides of fatty acids (such as C 8 -C 10  fatty acid dimethylamide) and chlorinated hydrocarbons. An EC product may spontaneously emulsify on addition to water, to produce an emulsion with sufficient stability to allow spray application through appropriate equipment. Preparation of an EW involves obtaining a compound of formula (I) either as a liquid (if it is not a liquid at room temperature, it may be melted at a reasonable temperature, typically below 70° C.) or in solution (by dissolving it in an appropriate solvent) and then emulsifiying the resultant liquid or solution into water containing one or more SFAs, under high shear, to produce an emulsion. Suitable solvents for use in EWs include vegetable oils, chlorinated hydrocarbons (such as chlorobenzenes), aromatic solvents (such as alkylbenzenes or alkylnaphthalenes) and other appropriate organic solvents which have a low solubility in water. 
     Microemulsions (ME) may be prepared by mixing water with a blend of one or more solvents with one or more SFAs, to produce spontaneously a thermodynamically stable isotropic liquid formulation. A compound of formula (I) is present initially in either the water or the solvent/SFA blend. Suitable solvents for use in MEs include those hereinbefore described for use in ECs or in EWs. An ME may be either an oil-in-water or a water-in-oil system (which system is present may be determined by conductivity measurements) and may be suitable for mixing water-soluble and oil-soluble pesticides in the same formulation. An ME is suitable for dilution into water, either remaining as a microemulsion or forming a conventional oil-in-water emulsion. 
     Suspension concentrates (SC) may comprise aqueous or non-aqueous suspensions of finely divided insoluble solid particles of a compound of formula (I). SCs may be prepared by ball or bead milling the solid compound of formula (I) in a suitable medium, optionally with one or more dispersing agents, to produce a fine particle suspension of the compound. One or more wetting agents may be included in the composition and a suspending agent may be included to reduce the rate at which the particles settle. Alternatively, a compound of formula (I) may be dry milled and added to water, containing agents hereinbefore described, to produce the desired end product. 
     Aerosol formulations comprise a compound of formula (I) and a suitable propellant (for example n-butane). A compound of formula (I) may also be dissolved or dispersed in a suitable medium (for example water or a water miscible liquid, such as n-propanol) to provide compositions for use in non-pressurised, hand-actuated spray pumps. 
     A compound of formula (I) may be mixed in the dry state with a pyrotechnic mixture to form a composition suitable for generating, in an enclosed space, a smoke containing the compound. 
     Capsule suspensions (CS) may be prepared in a manner similar to the preparation of EW formulations but with an additional polymerisation stage such that an aqueous dispersion of oil droplets is obtained, in which each oil droplet is encapsulated by a polymeric shell and contains a compound of formula (I) and, optionally, a carrier or diluent therefor. The polymeric shell may be produced by either an interfacial polycondensation reaction or by a coacervation procedure. The compositions may provide for controlled release of the compound of formula (I) and they may be used for seed treatment. A compound of formula (I) may also be formulated in a biodegradable polymeric matrix to provide a slow, controlled release of the compound. 
     A composition may include one or more additives to improve the biological performance of the composition (for example by improving wetting, retention or distribution on surfaces; resistance to rain on treated surfaces; or uptake or mobility of a compound of formula (I)). Such additives include surface active agents, spray additives based on oils, for example certain mineral oils or natural plant oils (such as soy bean and rape seed oil), and blends of these with other bio-enhancing adjuvants (ingredients which may aid or modify the action of a compound of formula (I)). 
     A compound of formula (I) may also be formulated for use as a seed treatment, for example as a powder composition, including a powder for dry seed treatment (DS), a water soluble powder (SS) or a water dispersible powder for slurry treatment (WS), or as a liquid composition, including a flowable concentrate (FS), a solution (LS) or a capsule suspension (CS). The preparations of DS, SS, WS, FS and LS compositions are very similar to those of, respectively, DP, SP, WP, SC and DC compositions described above. Compositions for treating seed may include an agent for assisting the adhesion of the composition to the seed (for example a mineral oil or a film-forming barrier). 
     Wetting agents, dispersing agents and emulsifying agents may be surface SFAs of the cationic, anionic, amphoteric or non-ionic type. 
     Suitable SFAs of the cationic type include quaternary ammonium compounds (for example cetyltrimethyl ammonium bromide), imidazolines and amine salts. Suitable anionic SFAs include alkali metals salts of fatty acids, salts of aliphatic monoesters of sulfuric acid (for example sodium lauryl sulfate), salts of sulfonated aromatic compounds (for example sodium dodecylbenzenesulfonate, calcium dodecylbenzenesulfonate, butylnaphthalene sulfonate and mixtures of sodium di-isopropyl- and tri-isopropyl-naphthalene sulfonates), ether sulfates, alcohol ether sulfates (for example sodium laureth-3-sulfate), ether carboxylates (for example sodium laureth-3-carboxylate), phosphate esters (products from the reaction between one or more fatty alcohols and phosphoric acid (predominately mono-esters) or phosphorus pentoxide (predominately di-esters), for example the reaction between lauryl alcohol and tetraphosphoric acid; additionally these products may be ethoxylated), sulfosuccinamates, paraffin or olefine sulfonates, taurates and lignosulfonates. 
     Suitable SFAs of the amphoteric type include betaines, propionates and glycinates. 
     Suitable SFAs of the non-ionic type include condensation products of alkylene oxides, such as ethylene oxide, propylene oxide, butylene oxide or mixtures thereof, with fatty alcohols (such as oleyl alcohol or cetyl alcohol) or with alkylphenols (such as octylphenol, nonylphenol or octylcresol); partial esters derived from long chain fatty acids or hexitol anhydrides; condensation products of said partial esters with ethylene oxide; block polymers (comprising ethylene oxide and propylene oxide); alkanolamides; simple esters (for example fatty acid polyethylene glycol esters); amine oxides (for example lauryl dimethyl amine oxide); and lecithins. 
     Suitable suspending agents include hydrophilic colloids (such as polysaccharides, polyvinylpyrrolidone or sodium carboxymethylcellulose) and swelling clays (such as bentonite or attapulgite). 
     A compound of formula (I) may be applied by any of the known means of applying pesticidal compounds. For example, it may be applied, formulated or unformulated, to the pests or to a locus of the pests (such as a habitat of the pests, or a growing plant liable to infestation by the pests) or to any part of the plant, including the foliage, stems, branches or roots, to the seed before it is planted or to other media in which plants are growing or are to be planted (such as soil surrounding the roots, the soil generally, paddy water or hydroponic culture systems), directly or it may be sprayed on, dusted on, applied by dipping, applied as a cream or paste formulation, applied as a vapour or applied through distribution or incorporation of a composition (such as a granular composition or a composition packed in a water-soluble bag) in soil or an aqueous environment. 
     A compound of formula (I) may also be injected into plants or sprayed onto vegetation using electrodynamic spraying techniques or other low volume methods, or applied by land or aerial irrigation systems. 
     Compositions for use as aqueous preparations (aqueous solutions or dispersions) are generally supplied in the form of a concentrate containing a high proportion of the active ingredient, the concentrate being added to water before use. These concentrates, which may include DCs, SCs, ECs, EWs, MEs, SGs, SPs, WPs, WGs and CSs, are often required to withstand storage for prolonged periods and, after such storage, to be capable of addition to water to form aqueous preparations which remain homogeneous for a sufficient time to enable them to be applied by conventional spray equipment. Such aqueous preparations may contain varying amounts of a compound of formula (I) (for example 0.0001 to 10%, by weight) depending upon the purpose for which they are to be used. 
     A compound of formula (I) may be used in mixtures with fertilisers (for example nitrogen-, potassium- or phosphorus-containing fertilisers). Suitable formulation types include granules of fertiliser. The mixtures preferably contain up to 25% by weight of the compound of formula (I). 
     The invention therefore also provides a fertiliser composition comprising a fertiliser and a compound of formula (I). 
     The compositions of this invention may contain other compounds having biological activity, for example micronutrients or compounds having fungicidal activity or which possess plant growth regulating, herbicidal, insecticidal, nematicidal or acaricidal activity. 
     The compound of formula I (herein after abbreviated by the term “TX” thus means a compound encompassed by the compounds of formula I, or preferably the term “TX” refers to a compound selected from the Tables 1 to 12, A, B and C) may be the sole active ingredient of the composition or it may be admixed with one or more additional active ingredients such as a pesticide (insect, acarine, mollusc and nematode pesticide), fungicide, synergist, herbicide, safener or plant growth regulator where appropriate. The activity of the compositions according to the invention may thereby be broadened considerably and may have surprising advantages which can also be described, in a wider sense, as synergistic activity. An additional active ingredient may: provide a composition having a broader spectrum of activity or increased persistence at a locus; provide a composition demonstrating better plant/crop tolerance by reducing phytotoxicity; provide a composition controlling insects in their different development stages; synergise the activity or complement the activity (for example by increasing the speed of effect or overcoming repellency) of the TX; or help to overcome or prevent the development of resistance to individual components. The particular additional active ingredient will depend upon the intended utility of the composition. Examples of suitable pesticides include the following: 
     a) Pyrethroids, such as permethrin, cypermethrin, fenvalerate, esfenvalerate, deltamethrin, cyhalothrin (in particular lambda-cyhalothrin), bifenthrin, fenpropathrin, cyfluthrin, tefluthrin, fish safe pyrethroids (for example ethofenprox), natural pyrethrin, tetramethrin, s-bioallethrin, fenfluthrin, prallethrin or 5-benzyl-3-furylmethyl-( E )-(1R,3S)-2,2-dimethyl-3-(2-oxothiolan-3-ylidenemethyl)cyclopropane carboxylate; 
     b) Organophosphates, such as, profenofos, sulprofos, acephate, methyl parathion, azinphos-methyl, demeton-s-methyl, heptenophos, thiometon, fenamiphos, monocrotophos, profenofos, triazophos, methamidophos, dimethoate, phosphamidon, malathion, chlorpyrifos, phosalone, terbufos, fensulfothion, fonofos, phorate, phoxim, pirimiphos-methyl, pirimiphos-ethyl, fenitrothion, fosthiazate or diazinon; 
     c) Carbamates (including aryl carbamates), such as pirimicarb, triazamate, cloethocarb, carbofuran, furathiocarb, ethiofencarb, aldicarb, thiofurox, carbosulfan, bendiocarb, fenobucarb, propoxur, methomyl or oxamyl; 
     d) Benzoyl ureas, such as diflubenzuron, triflumuron, hexaflumuron, flufenoxuron or chlorfluazuron; 
     e) Organic tin compounds, such as cyhexatin, fenbutatin oxide or azocyclotin; 
     f) Pyrazoles, such as tebufenpyrad and fenpyroximate; 
     g) Macrolides, such as avermectins or milbemycins, for example abamectin, emamectin benzoate, ivermectin, milbemycin, or spinosad, spinetoram or azadirachtin; 
     h) Hormones or pheromones; 
     i) Organochlorine compounds such as endosulfan, benzene hexachloride, DDT, chlordane or dieldrin; to j) Amidines, such as chlordimeform or amitraz; 
     k) Fumigant agents, such as chloropicrin, dichloropropane, methyl bromide or metam; 
     l) Neonicotinoid compounds such as imidacloprid, thiacloprid, acetamiprid, clothianidin, nitenpyram, dinotefuran or thiamethoxam; 
     m) Diacylhydrazines, such as tebufenozide, chromafenozide or methoxyfenozide; 
     n) Diphenyl ethers, such as diofenolan or pyriproxifen; 
     o) Indoxacarb; 
     p) Chlorfenapyr; 
     q) Pymetrozine or pyrifluquinazon; 
     r) Spirotetramat, spirodiclofen or spiromesifen; 
     s) Flubendiamide, chloranthraliniprole, or cyanthraniliprole; 
     t) Cyenopyrafen or cyflumetofen; or 
     u) Sulfoxaflor. 
     In addition to the major chemical classes of pesticide listed above, other pesticides having particular targets may be employed in the composition, if appropriate for the intended utility of the composition. For instance, selective insecticides for particular crops, for example stemborer specific insecticides (such as cartap) or hopper specific insecticides (such as buprofezin) for use in rice may be employed. Alternatively insecticides or acaricides specific for particular insect species/stages may also be included in the compositions (for example acaricidal ovo-larvicides, such as clofentezine, flubenzimine, hexythiazox or tetradifon; acaricidal motilicides, such as dicofol or propargite; acaricides, such as bromopropylate or chlorobenzilate; or growth regulators, such as hydramethylnon, cyromazine, methoprene, chlorfluazuron or diflubenzuron). 
     The following mixtures of the compounds of formula I with active ingredients are preferred, wherein, preferably, the term “TX” refers to a compound covered by the compounds of formula I or preferably the term “TX” refers to a compound selected from the Tables 1 to 12, A, B and C: 
     an adjuvant selected from the group of substances consisting of petroleum oils (alternative name) (628)+TX,
 
an acaricide selected from the group of substances consisting of 1,1-bis(4-chlorophenyl)-2-ethoxyethanol (IUPAC name) (910)+TX, 2,4-dichlorophenyl benzenesulfonate (IUPAC/Chemical Abstracts name) (1059)+TX, 2-fluoro-N-methyl-N-1-naphthylacetamide (IUPAC name) (1295)+TX, 4-chlorophenyl phenyl sulfone (IUPAC name) (981)+TX, abamectin (1)+TX, acequinocyl (3)+TX, acetoprole [CCN]+TX, acrinathrin (9)+TX, aldicarb (16)+TX, aldoxycarb (863)+TX, alpha-cypermethrin (202)+TX, amidithion (870)+TX, amidoflumet [CCN]+TX, amidothioate (872)+TX, amiton (875)+TX, amiton hydrogen oxalate (875)+TX, amitraz (24)+TX, aramite (881)+TX, arsenous oxide (882)+TX, AVI 382 (compound code)+TX, AZ 60541 (compound code)+TX, azinphos-ethyl (44)+TX, azinphos-methyl (45)+TX, azobenzene (IUPAC name) (888)+TX, azocyclotin (46)+TX, azothoate (889)+TX, benomyl (62)+TX, benoxafos (alternative name) [CCN]+TX, benzoximate (71)+TX, benzyl benzoate (IUPAC name) [CCN]+TX, bifenazate (74)+TX, bifenthrin (76)+TX, binapacryl (907)+TX, brofenvalerate (alternative name)+TX, bromocyclen (918)+TX, bromophos (920)+TX, bromophos-ethyl (921)+TX, bromopropylate (94)+TX, buprofezin (99)+TX, butocarboxim (103)+TX, butoxycarboxim (104)+TX, butylpyridaben (alternative name)+TX, calcium polysulfide (IUPAC name) (111)+TX, camphechlor (941)+TX, carbanolate (943)+TX, carbaryl (115)+TX, carbofuran (118)+TX, carbophenothion (947)+TX, CGA 50′439 (development code) (125)+TX, chinomethionat (126)+TX, chlorbenside (959)+TX, chlordimeform (964)+TX, chlordimeform hydrochloride (964)+TX, chlorfenapyr (130)+TX, chlorfenethol (968)+TX, chlorfenson (970)+TX, chlorfensulphide (971)+TX, chlorfenvinphos (131)+TX, chlorobenzilate (975)+TX, chloromebuform (977)+TX, chloromethiuron (978)+TX, chloropropylate (983)+TX, chlorpyrifos (145)+TX, chlorpyrifos-methyl (146)+TX, chlorthiophos (994)+TX, cinerin I (696)+TX, cinerin II (696)+TX, cinerins (696)+TX, clofentezine (158)+TX, closantel (alternative name) [CCN]+TX, coumaphos (174)+TX, crotamiton (alternative name) [CCN]+TX, crotoxyphos (1010)+TX, cufraneb (1013)+TX, cyanthoate (1020)+TX, cyflumetofen (CAS Reg. No.: 400882-07-7)+TX, cyhalothrin (196)+TX, cyhexatin (199)+TX, cypermethrin (201)+TX, DCPM (1032)+TX, DDT (219)+TX, demephion (1037)+TX, demephion-O (1037)+TX, demephion-S (1037)+TX, demeton (1038)+TX, demeton-methyl (224)+TX, demeton-O (1038)+TX, demeton-O-methyl (224)+TX, demeton-S (1038)+TX, demeton-5-methyl (224)+TX, demeton-5-methylsulphon (1039)+TX, diafenthiuron (226)+TX, dialifos (1042)+TX, diazinon (227)+TX, dichlofluanid (230)+TX, dichlorvos (236)+TX, dicliphos (alternative name)+TX, dicofol (242)+TX, dicrotophos (243)+TX, dienochlor (1071)+TX, dimefox (1081)+TX, dimethoate (262)+TX, dinactin (alternative name) (653)+TX, dinex (1089)+TX, dinex-diclexine (1089)+TX, dinobuton (269)+TX, dinocap (270)+TX, dinocap-4 [CCN]+TX, dinocap-6 [CCN]+TX, dinocton (1090)+TX, dinopenton (1092)+TX, dinosulfon (1097)+TX, dinoterbon (1098)+TX, dioxathion (1102)+TX, diphenyl sulfone (IUPAC name) (1103)+TX, disulfuram (alternative name) [CCN]+TX, disulfoton (278)+TX, DNOC (282)+TX, dofenapyn (1113)+TX, doramectin (alternative name) [CCN]+TX, endosulfan (294)+TX, endothion (1121)+TX, EPN (297)+TX, eprinomectin (alternative name) [CCN]+TX, ethion (309)+TX, ethoate-methyl (1134)+TX, etoxazole (320)+TX, etrimfos (1142)+TX, fenazaflor (1147)+TX, fenazaquin (328)+TX, fenbutatin oxide (330)+TX, fenothiocarb (337)+TX, fenpropathrin (342)+TX, fenpyrad (alternative name)+TX, fenpyroximate (345)+TX, fenson (1157)+TX, fentrifanil (1161)+TX, fenvalerate (349)+TX, fipronil (354)+TX, fluacrypyrim (360)+TX, fluazuron (1166)+TX, flubenzimine (1167)+TX, flucycloxuron (366)+TX, flucythrinate (367)+TX, fluenetil (1169)+TX, flufenoxuron (370)+TX, flumethrin (372)+TX, fluorbenside (1174)+TX, fluvalinate (1184)+TX, FMC 1137 (development code) (1185)+TX, formetanate (405)+TX, formetanate hydrochloride (405)+TX, formothion (1192)+TX, formparanate (1193)+TX, gamma-HCH (430)+TX, glyodin (1205)+TX, halfenprox (424)+TX, heptenophos (432)+TX, hexadecyl cyclopropanecarboxylate (IUPAC/Chemical Abstracts name) (1216)+TX, hexythiazox (441)+TX, iodomethane (IUPAC name) (542)+TX, isocarbophos (alternative name) (473)+TX, isopropyl O-(methoxyaminothiophosphoryl)salicylate (IUPAC name) (473)+TX, ivermectin (alternative name) [CCN]+TX, jasmolin I (696)+TX, jasmolin II (696)+TX, jodfenphos (1248)+TX, lindane (430)+TX, lufenuron (490)+TX, malathion (492)+TX, malonoben (1254)+TX, mecarbam (502)+TX, mephosfolan (1261)+TX, mesulfen (alternative name) [CCN]+TX, methacrifos (1266)+TX, methamidophos (527)+TX, methidathion (529)+TX, methiocarb (530)+TX, methomyl (531)+TX, methyl bromide (537)+TX, metolcarb (550)+TX, mevinphos (556)+TX, mexacarbate (1290)+TX, milbemectin (557)+TX, milbemycin oxime (alternative name) [CCN]+TX, mipafox (1293)+TX, monocrotophos (561)+TX, morphothion (1300)+TX, moxidectin (alternative name) [CCN]+TX, naled (567)+TX, NC-184 (compound code)+TX, NC-512 (compound code)+TX, nifluridide (1309)+TX, nikkomycins (alternative name) [CCN]+TX, nitrilacarb (1313)+TX, nitrilacarb 1:1 zinc chloride complex (1313)+TX, NNI-0101 (compound code)+TX, NNI-0250 (compound code)+TX, omethoate (594)+TX, oxamyl (602)+TX, oxydeprofos (1324)+TX, oxydisulfoton (1325)+TX, pp&#39;-DDT (219)+TX, parathion (615)+TX, permethrin (626)+TX, petroleum oils (alternative name) (628)+TX, phenkapton (1330)+TX, phenthoate (631)+TX, phorate (636)+TX, phosalone (637)+TX, phosfolan (1338)+TX, phosmet (638)+TX, phosphamidon (639)+TX, phoxim (642)+TX, pirimiphos-methyl (652)+TX, polychloroterpenes (traditional name) (1347)+TX, polynactins (alternative name) (653)+TX, proclonol (1350)+TX, profenofos (662)+TX, promacyl (1354)+TX, propargite (671)+TX, propetamphos (673)+TX, propoxur (678)+TX, prothidathion (1360)+TX, prothoate (1362)+TX, pyrethrin I (696)+TX, pyrethrin II (696)+TX, pyrethrins (696)+TX, pyridaben (699)+TX, pyridaphenthion (701)+TX, pyrimidifen (706)+TX, pyrimitate (1370)+TX, quinalphos (711)+TX, quintiofos (1381)+TX, R-1492 (development code) (1382)+TX, RA-17 (development code) (1383)+TX, rotenone (722)+TX, schradan (1389)+TX, sebufos (alternative name)+TX, selamectin (alternative name) [CCN]+TX, SI-0009 (compound code)+TX, sophamide (1402)+TX, spirodiclofen (738)+TX, spiromesifen (739)+TX, SSI-121 (development code) (1404)+TX, sulfuram (alternative name) [CCN]+TX, sulfluramid (750)+TX, sulfotep (753)+TX, sulphur (754)+TX, SZI-121 (development code) (757)+TX, tau-fluvalinate (398)+TX, tebufenpyrad (763)+TX, TEPP (1417)+TX, terbam (alternative name)+TX, tetrachlorvinphos (777)+TX, tetradifon (786)+TX, tetranactin (alternative name) (653)+TX, tetrasul (1425)+TX, thiafenox (alternative name)+TX, thiocarboxime (1431)+TX, thiofanox (800)+TX, thiometon (801)+TX, thioquinox (1436)+TX, thuringiensin (alternative name) [CCN]+TX, triamiphos (1441)+TX, triarathene (1443)+TX, triazophos (820)+TX, triazuron (alternative name)+TX, trichlorfon (824)+TX, trifenofos (1455)+TX, trinactin (alternative name) (653)+TX, vamidothion (847)+TX, vaniliprole [CCN] and yl-5302 (compound code)+TX, an algicide selected from the group of substances consisting of bethoxazin [CCN]+TX, copper dioctanoate (IUPAC name) (170)+TX, copper sulfate (172)+TX, cybutryne [CCN]+TX, dichlone (1052)+TX, dichlorophen (232)+TX, endothal (295)+TX, fentin (347)+TX, hydrated lime [CCN]+TX, nabam (566)+TX, quinoclamine (714)+TX, quinonamid (1379)+TX, simazine (730)+TX, triphenyltin acetate (IUPAC name) (347) and triphenyltin hydroxide (IUPAC name) (347)+TX, an anthelmintic selected from the group of substances consisting of abamectin (1)+TX, crufomate (1011)+TX, doramectin (alternative name) [CCN]+TX, emamectin (291)+TX, emamectin benzoate (291)+TX, eprinomectin (alternative name) [CCN]+TX, ivermectin (alternative name) [CCN]+TX, milbemycin oxime (alternative name) [CCN]+TX, moxidectin (alternative name) [CCN]+TX, piperazine [CCN]+TX, selamectin (alternative name) [CCN]+TX, spinosad (737) and thiophanate (1435)+TX,
 
an avicide selected from the group of substances consisting of chloralose (127)+TX, endrin (1122)+TX, fenthion (346)+TX, pyridin-4-amine (IUPAC name) (23) and strychnine (745)+TX,
 
a bactericide selected from the group of substances consisting of 1-hydroxy-1H-pyridine-2-thione (IUPAC name) (1222)+TX, 4-(quinoxalin-2-ylamino)benzenesulfonamide (IUPAC name) (748)+TX, 8-hydroxyquinoline sulfate (446)+TX, bronopol (97)+TX, copper dioctanoate (IUPAC name) (170)+TX, copper hydroxide (IUPAC name) (169)+TX, cresol [CCN]+TX, dichlorophen (232)+TX, dipyrithione (1105)+TX, dodicin (1112)+TX, fenaminosulf (1144)+TX, formaldehyde (404)+TX, hydrargaphen (alternative name) [CCN]+TX, kasugamycin (483)+TX, kasugamycin hydrochloride hydrate (483)+TX, nickel bis(dimethyldithiocarbamate) (IUPAC name) (1308)+TX, nitrapyrin (580)+TX, octhilinone (590)+TX, oxolinic acid (606)+TX, oxytetracycline (611)+TX, potassium hydroxyquinoline sulfate (446)+TX, probenazole (658)+TX, streptomycin (744)+TX, streptomycin sesquisulfate (744)+TX, tecloftalam (766)+TX, and thiomersal (alternative name) [CCN]+TX,
 
a biological agent selected from the group of substances consisting of  Adoxophyes orana  GV (alternative name) (12)+TX,  Agrobacterium  radiobacter (alternative name) (13)+TX,  Amblyseius  spp. (alternative name) (19)+TX,  Anagrapha falcifera  NPV (alternative name) (28)+TX,  Anagrus atomus  (alternative name) (29)+TX,  Aphelinus abdominalis  (alternative name) (33)+TX,  Aphidius colemani  (alternative name) (34)+TX,  Aphidoletes aphidimyza  (alternative name) (35)+TX,  Autographa califormica  NPV (alternative name) (38)+TX,  Bacillus firmus  (alternative name) (48)+TX,  Bacillus sphaericus  Neide (scientific name) (49)+TX,  Bacillus thuringiensis  Berliner (scientific name) (51)+TX,  Bacillus thuringiensis  subsp.  aizawai  (scientific name) (51)+TX,  Bacillus thuringiensis  subsp.  israelensis  (scientific name) (51)+TX,  Bacillus thuringiensis  subsp.  japonensis  (scientific name) (51)+TX,  Bacillus thuringiensis  subsp.  kurstaki  (scientific name) (51)+TX,  Bacillus thuringiensis  subsp.  tenebrionis  (scientific name) (51)+TX,  Beauveria bassiana  (alternative name) (53)+TX,  Beauveria brongniartii  (alternative name) (54)+TX,  Chrysoperla carnea  (alternative name) (151)+TX,  Cryptolaemus montrouzieri  (alternative name) (178)+TX,  Cydia pomonella  GV (alternative name) (191)+TX,  Dacnusa sibirica  (alternative name) (212)+TX,  Diglyphus isaea  (alternative name) (254)+TX,  Encarsia formosa  (scientific name) (293)+TX,  Eretmocerus eremicus  (alternative name) (300)+TX,  Helicoverpa zea  NPV (alternative name) (431)+TX,  Heterorhabditis bacteriophora  and  H. megidis  (alternative name) (433)+TX,  Hippodamia convergens  (alternative name) (442)+TX,  Leptomastix dactylopii  (alternative name) (488)+TX,  Macrolophus caliginosus  (alternative name) (491)+TX,  Mamestra brassicae  NPV (alternative name) (494)+TX,  Metaphycus helvolus  (alternative name) (522)+TX,  Metarhizium anisopliae  var.  acridum  (scientific name) (523)+TX,  Metarhizium anisopliae  var.  anisopliae  (scientific name) (523)+TX,  Neodiprion sertifer  NPV and  N. lecontei  NPV (alternative name) (575)+TX,  Onus  spp. (alternative name) (596)+TX,  Paecilomyces fumosoroseus  (alternative name) (613)+TX,  Phytoseiulus persimilis  (alternative name) (644)+TX,  Spodoptera exigua  multicapsid nuclear polyhedrosis virus (scientific name) (741)+TX,  Steinernema bibionis  (alternative name) (742)+TX,  Steinernema carpocapsae  (alternative name) (742)+TX,  Steinernema feltiae  (alternative name) (742)+TX,  Steinernema glaseri  (alternative name) (742)+TX,  Steinernema riobrave  (alternative name) (742)+TX,  Steinernema riobravis  (alternative name) (742)+TX,  Steinernema scapterisci  (alternative name) (742)+TX,  Steinernema  spp. (alternative name) (742)+TX,  Trichogramma  spp. (alternative name) (826)+TX,  Typhlodromus occidentalis  (alternative name) (844) and  Verticillium lecanii  (alternative name) (848)+TX,
 
a soil sterilant selected from the group of substances consisting of iodomethane (IUPAC name) (542) and methyl bromide (537)+TX,
 
a chemosterilant selected from the group of substances consisting of apholate [CCN]+TX, bisazir (alternative name) [CCN]+TX, busulfan (alternative name) [CCN]+TX, diflubenzuron (250)+TX, dimatif (alternative name) [CCN]+TX, hemel [CCN]+TX, hempa [CCN]+TX, metepa [CCN]+TX, methiotepa [CCN]+TX, methyl apholate [CCN]+TX, morzid [CCN]+TX, penfluoron (alternative name) [CCN]+TX, tepa [CCN]+TX, thiohempa (alternative name) [CCN]+TX, thiotepa (alternative name) [CCN]+TX, tretamine (alternative name) [CCN] and uredepa (alternative name) [CCN]+TX,
 
an insect pheromone selected from the group of substances consisting of (E)-dec-5-en-1-yl acetate with (E)-dec-5-en-1-ol (IUPAC name) (222)+TX, (E)-tridec-4-en-1-yl acetate (IUPAC name) (829)+TX, (E)-6-methylhept-2-en-4-ol (IUPAC name) (541)+TX, (E,Z)-tetradeca-4,10-dien-1-yl acetate (IUPAC name) (779)+TX, (Z)-dodec-7-en-1-yl acetate (IUPAC name) (285)+TX, (Z)-hexadec-11-enal (IUPAC name) (436)+TX, (Z)-hexadec-11-en-1-yl acetate (IUPAC name) (437)+TX, (Z)-hexadec-13-en-11-yn-1-yl acetate (IUPAC name) (438)+TX, (Z)-icos-13-en-10-one (IUPAC name) (448)+TX, (Z)-tetradec-7-en-1-al (IUPAC name) (782)+TX, (Z)-tetradec-9-en-1-ol (IUPAC name) (783)+TX, (Z)-tetradec-9-en-1-yl acetate (IUPAC name) (784)+TX, (7E,9Z)-dodeca-7,9-dien-1-yl acetate (IUPAC name) (283)+TX, (9Z,11E)-tetradeca-9,11-dien-1-yl acetate (IUPAC name) (780)+TX, (9Z,12E)-tetradeca-9,12-dien-1-yl acetate (IUPAC name) (781)+TX, 14-methyloctadec-1-ene (IUPAC name) (545)+TX, 4-methylnonan-5-ol with 4-methylnonan-5-one (IUPAC name) (544)+TX, alpha-multistriatin (alternative name) [CCN]+TX, brevicomin (alternative name) [CCN]+TX, codlelure (alternative name) [CCN]+TX, codlemone (alternative name) (167)+TX, cuelure (alternative name) (179)+TX, disparlure (277)+TX, dodec-8-en-1-yl acetate (IUPAC name) (286)+TX, dodec-9-en-1-yl acetate (IUPAC name) (287)+TX, dodeca-8+TX, 10-dien-1-yl acetate (IUPAC name) (284)+TX, dominicalure (alternative name) [CCN]+TX, ethyl 4-methyloctanoate (IUPAC name) (317)+TX, eugenol (alternative name) [CCN]+TX, frontalin (alternative name) [CCN]+TX, gossyplure (alternative name) (420)+TX, grandlure (421)+TX, grandlure I (alternative name) (421)+TX, grandlure II (alternative name) (421)+TX, grandlure III (alternative name) (421)+TX, grandlure IV (alternative name) (421)+TX, hexylure [CCN]+TX, ipsdienol (alternative name) [CCN]+TX, ipsenol (alternative name) [CCN]+TX, japonilure (alternative name) (481)+TX, lineatin (alternative name) [CCN]+TX, litlure (alternative name) [CCN]+TX, looplure (alternative name) [CCN]+TX, medlure [CCN]+TX, megatomoic acid (alternative name) [CCN]+TX, methyl eugenol (alternative name) (540)+TX, muscalure (563)+TX, octadeca-2,13-dien-1-yl acetate (IUPAC name) (588)+TX, octadeca-3,13-dien-1-yl acetate (IUPAC name) (589)+TX, orfralure (alternative name) [CCN]+TX, oryctalure (alternative name) (317)+TX, ostramone (alternative name) [CCN]+TX, siglure [CCN]+TX, sordidin (alternative name) (736)+TX, sulcatol (alternative name) [CCN]+TX, tetradec-11-en-1-yl acetate (IUPAC name) (785)+TX, trimedlure (839)+TX, trimedlure A (alternative name) (839)+TX, trimedlure B 1  (alternative name) (839)+TX, trimedlure B 2  (alternative name) (839)+TX, trimedlure C (alternative name) (839) and trunc-call (alternative name) [CCN]+TX,
 
an insect repellent selected from the group of substances consisting of 2-(octylthio)ethanol (IUPAC name) (591)+TX, butopyronoxyl (933)+TX, butoxy(polypropylene glycol) (936)+TX, dibutyl adipate (IUPAC name) (1046)+TX, dibutyl phthalate (1047)+TX, dibutyl succinate (IUPAC name) (1048)+TX, diethyltoluamide [CCN]+TX, dimethyl carbate [CCN]+TX, dimethyl phthalate [CCN]+TX, ethyl hexanediol (1137)+TX, hexamide [CCN]+TX, methoquin-butyl (1276)+TX, methylneodecanamide [CCN]+TX, oxamate [CCN] and picaridin [CCN]+TX,
 
an insecticide selected from the group of substances consisting of 1-dichloro-1-nitroethane (IUPAC/Chemical Abstracts name) (1058)+TX, 1,1-dichloro-2,2-bis(4-ethylphenyl)ethane (IUPAC name) (1056), +TX, 1,2-dichloropropane (IUPAC/Chemical Abstracts name) (1062)+TX, 1,2-dichloropropane with 1,3-dichloropropene (IUPAC name) (1063)+TX, 1-bromo-2-chloroethane (IUPAC/Chemical Abstracts name) (916)+TX, 2,2,2-trichloro-1-(3,4-dichlorophenyl)ethyl acetate (IUPAC name) (1451)+TX, 2,2-dichlorovinyl 2-ethylsulphinylethyl methyl phosphate (IUPAC name) (1066)+TX, 2-(1,3-dithiolan-2-yl)phenyl dimethylcarbamate (IUPAC/Chemical Abstracts name) (1109)+TX, 2-(2-butoxyethoxy)ethyl thiocyanate (IUPAC/Chemical Abstracts name) (935)+TX, 2-(4,5-dimethyl-1,3-dioxolan-2-yl)phenyl methylcarbamate (IUPAC/Chemical Abstracts name) (1084)+TX, 2-(4-chloro-3,5-xylyloxy)ethanol (IUPAC name) (986)+TX, 2-chlorovinyl diethyl phosphate (IUPAC name) (984)+TX, 2-imidazolidone (IUPAC name) (1225)+TX, 2-isovalerylindan-1,3-dione (IUPAC name) (1246)+TX, 2-methyl(prop-2-ynyl)aminophenyl methylcarbamate (IUPAC name) (1284)+TX, 2-thiocyanatoethyl laurate (IUPAC name) (1433)+TX, 3-bromo-1-chloroprop-1-ene (IUPAC name) (917)+TX, 3-methyl-1-phenylpyrazol-5-yl dimethylcarbamate (IUPAC name) (1283)+TX, 4-methyl(prop-2-ynyl)amino-3,5-xylyl methylcarbamate (IUPAC name) (1285)+TX, 5,5-dimethyl-3-oxocyclohex-1-enyl dimethylcarbamate (IUPAC name) (1085)+TX, abamectin (1)+TX, acephate (2)+TX, acetamiprid (4)+TX, acethion (alternative name) [CCN]+TX, acetoprole [CCN]+TX, acrinathrin (9)+TX, acrylonitrile (IUPAC name) (861)+TX, alanycarb (15)+TX, aldicarb (16)+TX, aldoxycarb (863)+TX, aldrin (864)+TX, allethrin (17)+TX, allosamidin (alternative name) [CCN]+TX, allyxycarb (866)+TX, alpha-cypermethrin (202)+TX, alpha-ecdysone (alternative name) [CCN]+TX, aluminium phosphide (640)+TX, amidithion (870)+TX, amidothioate (872)+TX, aminocarb (873)+TX, amiton (875)+TX, amiton hydrogen oxalate (875)+TX, amitraz (24)+TX, anabasine (877)+TX, athidathion (883)+TX, AVI 382 (compound code)+TX, AZ 60541 (compound code)+TX, azadirachtin (alternative name) (41)+TX, azamethiphos (42)+TX, azinphos-ethyl (44)+TX, azinphos-methyl (45)+TX, azothoate (889)+TX,  Bacillus thuringiensis  delta endotoxins (alternative name) (52)+TX, barium hexafluorosilicate (alternative name) [CCN]+TX, barium polysulfide (IUPAC/Chemical Abstracts name) (892)+TX, barthrin [CCN]+TX, Bayer 22/190 (development code) (893)+TX, Bayer 22408 (development code) (894)+TX, bendiocarb (58)+TX, benfuracarb (60)+TX, bensultap (66)+TX, beta-cyfluthrin (194)+TX, beta-cypermethrin (203)+TX, bifenthrin (76)+TX, bioallethrin (78)+TX, bioallethrin S-cyclopentenyl isomer (alternative name) (79)+TX, bioethanomethrin [CCN]+TX, biopermethrin (908)+TX, bioresmethrin (80)+TX, bis(2-chloroethyl)ether (IUPAC name) (909)+TX, bistrifluoron (83)+TX, borax (86)+TX, brofenvalerate (alternative name)+TX, bromfenvinfos (914)+TX, bromocyclen (918)+TX, bromo-DDT (alternative name) [CCN]+TX, bromophos (920)+TX, bromophos-ethyl (921)+TX, bufencarb (924)+TX, buprofezin (99)+TX, butacarb (926)+TX, butathiofos (927)+TX, butocarboxim (103)+TX, butonate (932)+TX, butoxycarboxim (104)+TX, butylpyridaben (alternative name)+TX, cadusafos (109)+TX, calcium arsenate [CCN]+TX, calcium cyanide (444)+TX, calcium polysulfide (IUPAC name) (111)+TX, camphechlor (941)+TX, carbanolate (943)+TX, carbaryl (115)+TX, carbofuran (118)+TX, carbon disulfide (IUPAC/Chemical Abstracts name) (945)+TX, carbon tetrachloride (IUPAC name) (946)+TX, carbophenothion (947)+TX, carbosulfan (119)+TX, cartap (123)+TX, cartap hydrochloride (123)+TX, cevadine (alternative name) (725)+TX, chlorbicyclen (960)+TX, chlordane (128)+TX, chlordecone (963)+TX, chlordimeform (964)+TX, chlordimeform hydrochloride (964)+TX, chlorethoxyfos (129)+TX, chlorfenapyr (130)+TX, chlorfenvinphos (131)+TX, chlorfluazuron (132)+TX, chlormephos (136)+TX, chloroform [CCN]+TX, chloropicrin (141)+TX, chlorphoxim (989)+TX, chlorprazophos (990)+TX, chlorpyrifos (145)+TX, chlorpyrifos-methyl (146)+TX, chlorthiophos (994)+TX, chromafenozide (150)+TX, cinerin I (696)+TX, cinerin II (696)+TX, cinerins (696)+TX, cis-resmethrin (alternative name)+TX, cismethrin (80)+TX, clocythrin (alternative name)+TX, cloethocarb (999)+TX, closantel (alternative name) [CCN]+TX, clothianidin (165)+TX, copper acetoarsenite [CCN]+TX, copper arsenate [CCN]+TX, copper oleate [CCN]+TX, coumaphos (174)+TX, coumithoate (1006)+TX, crotamiton (alternative name) [CCN]+TX, crotoxyphos (1010)+TX, crufomate (1011)+TX, cryolite (alternative name) (177)+TX, CS 708 (development code) (1012)+TX, cyanofenphos (1019)+TX, cyanophos (184)+TX, cyanthoate (1020)+TX, cyclethrin [CCN]+TX, cycloprothrin (188)+TX, cyfluthrin (193)+TX, cyhalothrin (196)+TX, cypermethrin (201)+TX, cyphenothrin (206)+TX, cyromazine (209)+TX, cythioate (alternative name) [CCN]+TX, d-limonene (alternative name) [CCN]+TX, d-tetramethrin (alternative name) (788)+TX, DAEP (1031)+TX, dazomet (216)+TX, DDT (219)+TX, decarbofuran (1034)+TX, deltamethrin (223)+TX, demephion (1037)+TX, demephion-O (1037)+TX, demephion-S (1037)+TX, demeton (1038)+TX, demeton-methyl (224)+TX, demeton-O (1038)+TX, demeton-O-methyl (224)+TX, demeton-S (1038)+TX, demeton-5-methyl (224)+TX, demeton-5-methylsulphon (1039)+TX, diafenthiuron (226)+TX, dialifos (1042)+TX, diamidafos (1044)+TX, diazinon (227)+TX, dicapthon (1050)+TX, dichlofenthion (1051)+TX, dichlorvos (236)+TX, dicliphos (alternative name)+TX, dicresyl (alternative name) [CCN]+TX, dicrotophos (243)+TX, dicyclanil (244)+TX, dieldrin (1070)+TX, diethyl 5-methylpyrazol-3-yl phosphate (IUPAC name) (1076)+TX, diflubenzuron (250)+TX, dilor (alternative name) [CCN]+TX, dimefluthrin [CCN]+TX, dimefox (1081)+TX, dimetan (1085)+TX, dimethoate (262)+TX, dimethrin (1083)+TX, dimethylvinphos (265)+TX, dimetilan (1086)+TX, dinex (1089)+TX, dinex-diclexine (1089)+TX, dinoprop (1093)+TX, dinosam (1094)+TX, dinoseb (1095)+TX, dinotefuran (271)+TX, diofenolan (1099)+TX, dioxabenzofos (1100)+TX, dioxacarb (1101)+TX, dioxathion (1102)+TX, disulfoton (278)+TX, dithicrofos (1108)+TX, DNOC (282)+TX, doramectin (alternative name) [CCN]+TX, DSP (1115)+TX, ecdysterone (alternative name) [CCN]+TX, EI 1642 (development code) (1118)+TX, emamectin (291)+TX, emamectin benzoate (291)+TX, EMPC (1120)+TX, empenthrin (292)+TX, endosulfan (294)+TX, endothion (1121)+TX, endrin (1122)+TX, EPBP (1123)+TX, EPN (297)+TX, epofenonane (1124)+TX, eprinomectin (alternative name) [CCN]+TX, esfenvalerate (302)+TX, etaphos (alternative name) [CCN]+TX, ethiofencarb (308)+TX, ethion (309)+TX, ethiprole (310)+TX, ethoate-methyl (1134)+TX, ethoprophos (312)+TX, ethyl formate (IUPAC name) [CCN]+TX, ethyl-DDD (alternative name) (1056)+TX, ethylene dibromide (316)+TX, ethylene dichloride (chemical name) (1136)+TX, ethylene oxide [CCN]+TX, etofenprox (319)+TX, etrimfos (1142)+TX, EXD (1143)+TX, famphur (323)+TX, fenamiphos (326)+TX, fenazaflor (1147)+TX, fenchlorphos (1148)+TX, fenethacarb (1149)+TX, fenfluthrin (1150)+TX, fenitrothion (335)+TX, fenobucarb (336)+TX, fenoxacrim (1153)+TX, fenoxycarb (340)+TX, fenpirithrin (1155)+TX, fenpropathrin (342)+TX, fenpyrad (alternative name)+TX, fensulfothion (1158)+TX, fenthion (346)+TX, fenthion-ethyl [CCN]+TX, fenvalerate (349)+TX, fipronil (354)+TX, flonicamid (358)+TX, flubendiamide (CAS. Reg. No.: 272451-65-7)+TX, flucofuron (1168)+TX, flucycloxuron (366)+TX, flucythrinate (367)+TX, fluenetil (1169)+TX, flufenerim [CCN]+TX, flufenoxuron (370)+TX, flufenprox (1171)+TX, flumethrin (372)+TX, fluvalinate (1184)+TX, FMC 1137 (development code) (1185)+TX, fonofos (1191)+TX, formetanate (405)+TX, formetanate hydrochloride (405)+TX, formothion (1192)+TX, formparanate (1193)+TX, fosmethilan (1194)+TX, fospirate (1195)+TX, fosthiazate (408)+TX, fosthietan (1196)+TX, furathiocarb (412)+TX, furethrin (1200)+TX, gamma-cyhalothrin (197)+TX, gamma-HCH (430)+TX, guazatine (422)+TX, guazatine acetates (422)+TX, GY-81 (development code) (423)+TX, halfenprox (424)+TX, halofenozide (425)+TX, HCH (430)+TX, HEOD (1070)+TX, heptachlor (1211)+TX, heptenophos (432)+TX, heterophos [CCN]+TX, hexaflumuron (439)+TX, HHDN (864)+TX, hydramethylnon (443)+TX, hydrogen cyanide (444)+TX, hydroprene (445)+TX, hyquincarb (1223)+TX, imidacloprid (458)+TX, imiprothrin (460)+TX, indoxacarb (465)+TX, iodomethane (IUPAC name) (542)+TX, IPSP (1229)+TX, isazofos (1231)+TX, isobenzan (1232)+TX, isocarbophos (alternative name) (473)+TX, isodrin (1235)+TX, isofenphos (1236)+TX, isolane (1237)+TX, isoprocarb (472)+TX, isopropyl O-(methoxy-aminothiophosphoryl)salicylate (IUPAC name) (473)+TX, isoprothiolane (474)+TX, isothioate (1244)+TX, isoxathion (480)+TX, ivermectin (alternative name) [CCN]+TX, jasmolin I (696)+TX, jasmolin II (696)+TX, jodfenphos (1248)+TX, juvenile hormone I (alternative name) [CCN]+TX, juvenile hormone II (alternative name) [CCN]+TX, juvenile hormone III (alternative name) [CCN]+TX, kelevan (1249)+TX, kinoprene (484)+TX, lambda-cyhalothrin (198)+TX, lead arsenate [CCN]+TX, lepimectin (CCN)+TX, leptophos (1250)+TX, lindane (430)+TX, lirimfos (1251)+TX, lufenuron (490)+TX, lythidathion (1253)+TX, m-cumenyl methylcarbamate (IUPAC name) (1014)+TX, magnesium phosphide (IUPAC name) (640)+TX, malathion (492)+TX, malonoben (1254)+TX, mazidox (1255)+TX, mecarbam (502)+TX, mecarphon (1258)+TX, menazon (1260)+TX, mephosfolan (1261)+TX, mercurous chloride (513)+TX, mesulfenfos (1263)+TX, metaflumizone (CCN)+TX, metam (519)+TX, metam-potassium (alternative name) (519)+TX, metam-sodium (519)+TX, methacrifos (1266)+TX, methamidophos (527)+TX, methanesulphonyl fluoride (IUPAC/Chemical Abstracts name) (1268)+TX, methidathion (529)+TX, methiocarb (530)+TX, methocrotophos (1273)+TX, methomyl (531)+TX, methoprene (532)+TX, methoquin-butyl (1276)+TX, methothrin (alternative name) (533)+TX, methoxychlor (534)+TX, methoxyfenozide (535)+TX, methyl bromide (537)+TX, methyl isothiocyanate (543)+TX, methylchloroform (alternative name) [CCN]+TX, methylene chloride [CCN]+TX, metofluthrin [CCN]+TX, metolcarb (550)+TX, metoxadiazone (1288)+TX, mevinphos (556)+TX, mexacarbate (1290)+TX, milbemectin (557)+TX, milbemycin oxime (alternative name) [CCN]+TX, mipafox (1293)+TX, mirex (1294)+TX, monocrotophos (561)+TX, morphothion (1300)+TX, moxidectin (alternative name) [CCN]+TX, naftalofos (alternative name) [CCN]+TX, naled (567)+TX, naphthalene (IUPAC/Chemical Abstracts name) (1303)+TX, NC-170 (development code) (1306)+TX, NC-184 (compound code)+TX, nicotine (578)+TX, nicotine sulfate (578)+TX, nifluridide (1309)+TX, nitenpyram (579)+TX, nithiazine (1311)+TX, nitrilacarb (1313)+TX, nitrilacarb 1:1 zinc chloride complex (1313)+TX, NNI-0101 (compound code)+TX, NNI-0250 (compound code)+TX, nornicotine (traditional name) (1319)+TX, novaluron (585)+TX, noviflumuron (586)+TX, O-5-dichloro-4-iodophenyl O-ethyl ethylphosphonothioate (IUPAC name) (1057)+TX, O,O-diethyl O-4-methyl-2-oxo-2H-chromen-7-yl phosphorothioate (IUPAC name) (1074)+TX, O,O-diethyl O-6-methyl-2-propylpyrimidin-4-yl phosphorothioate (IUPAC name) (1075)+TX, O,O,O′,O′-tetrapropyl dithiopyrophosphate (IUPAC name) (1424)+TX, oleic acid (IUPAC name) (593)+TX, omethoate (594)+TX, oxamyl (602)+TX, oxydemeton-methyl (609)+TX, oxydeprofos (1324)+TX, oxydisulfoton (1325)+TX, pp′-DDT (219)+TX, para-dichlorobenzene [CCN]+TX, parathion (615)+TX, parathion-methyl (616)+TX, penfluoron (alternative name) [CCN]+TX, pentachlorophenol (623)+TX, pentachlorophenyl laurate (IUPAC name) (623)+TX, permethrin (626)+TX, petroleum oils (alternative name) (628)+TX, PH 60-38 (development code) (1328)+TX, phenkapton (1330)+TX, phenothrin (630)+TX, phenthoate (631)+TX, phorate (636)+TX, phosalone (637)+TX, phosfolan (1338)+TX, phosmet (638)+TX, phosnichlor (1339)+TX, phosphamidon (639)+TX, phosphine (IUPAC name) (640)+TX, phoxim (642)+TX, phoxim-methyl (1340)+TX, pirimetaphos (1344)+TX, pirimicarb (651)+TX, pirimiphos-ethyl (1345)+TX, pirimiphos-methyl (652)+TX, polychlorodicyclopentadiene isomers (IUPAC name) (1346)+TX, polychloroterpenes (traditional name) (1347)+TX, potassium arsenite [CCN]+TX, potassium thiocyanate [CCN]+TX, prallethrin (655)+TX, precocene I (alternative name) [CCN]+TX, precocene II (alternative name) [CCN]+TX, precocene III (alternative name) [CCN]+TX, primidophos (1349)+TX, profenofos (662)+TX, profluthrin [CCN]+TX, promacyl (1354)+TX, promecarb (1355)+TX, propaphos (1356)+TX, propetamphos (673)+TX, propoxur (678)+TX, prothidathion (1360)+TX, prothiofos (686)+TX, prothoate (1362)+TX, protrifenbute [CCN]+TX, pymetrozine (688)+TX, pyraclofos (689)+TX, pyrazophos (693)+TX, pyresmethrin (1367)+TX, pyrethrin I (696)+TX, pyrethrin II (696)+TX, pyrethrins (696)+TX, pyridaben (699)+TX, pyridalyl (700)+TX, pyridaphenthion (701)+TX, pyrimidifen (706)+TX, pyrimitate (1370)+TX, pyriproxyfen (708)+TX, quassia (alternative name) [CCN]+TX, quinalphos (711)+TX, quinalphos-methyl (1376)+TX, quinothion (1380)+TX, quintiofos (1381)+TX, R-1492 (development code) (1382)+TX, rafoxanide (alternative name) [CCN]+TX, resmethrin (719)+TX, rotenone (722)+TX, RU 15525 (development code) (723)+TX, RU 25475 (development code) (1386)+TX, ryania (alternative name) (1387)+TX, ryanodine (traditional name) (1387)+TX, sabadilla (alternative name) (725)+TX, schradan (1389)+TX, sebufos (alternative name)+TX, selamectin (alternative name) [CCN]+TX, SI-0009 (compound code)+TX, SI-0205 (compound code)+TX, SI-0404 (compound code)+TX, SI-0405 (compound code)+TX, silafluofen (728)+TX, SN 72129 (development code) (1397)+TX, sodium arsenite [CCN]+TX, sodium cyanide (444)+TX, sodium fluoride (IUPAC/Chemical Abstracts name) (1399)+TX, sodium hexafluorosilicate (1400)+TX, sodium pentachlorophenoxide (623)+TX, sodium selenate (IUPAC name) (1401)+TX, sodium thiocyanate [CCN]+TX, sophamide (1402)+TX, spinosad (737)+TX, spiromesifen (739)+TX, spirotetrmat (CCN)+TX, sulcofuron (746)+TX, sulcofuron-sodium (746)+TX, sulfluramid (750)+TX, sulfotep (753)+TX, sulphuryl fluoride (756)+TX, sulprofos (1408)+TX, tar oils (alternative name) (758)+TX, tau-fluvalinate (398)+TX, tazimcarb (1412)+TX, TDE (1414)+TX, tebufenozide (762)+TX, tebufenpyrad (763)+TX, tebupirimfos (764)+TX, teflubenzuron (768)+TX, tefluthrin (769)+TX, temephos (770)+TX, TEPP (1417)+TX, terallethrin (1418)+TX, terbam (alternative name)+TX, terbufos (773)+TX, tetrachloroethane [CCN]+TX, tetrachlorvinphos (777)+TX, tetramethrin (787)+TX, theta-cypermethrin (204)+TX, thiacloprid (791)+TX, thiafenox (alternative name)+TX, thiamethoxam (792)+TX, thicrofos (1428)+TX, thiocarboxime (1431)+TX, thiocyclam (798)+TX, thiocyclam hydrogen oxalate (798)+TX, thiodicarb (799)+TX, thiofanox (800)+TX, thiometon (801)+TX, thionazin (1434)+TX, thiosultap (803)+TX, thiosultap-sodium (803)+TX, thuringiensin (alternative name) [CCN]+TX, tolfenpyrad (809)+TX, tralomethrin (812)+TX, transfluthrin (813)+TX, transpermethrin (1440)+TX, triamiphos (1441)+TX, triazamate (818)+TX, triazophos (820)+TX, triazuron (alternative name)+TX, trichlorfon (824)+TX, trichlormetaphos-3 (alternative name) [CCN]+TX, trichloronat (1452)+TX, trifenofos (1455)+TX, triflumuron (835)+TX, trimethacarb (840)+TX, triprene (1459)+TX, vamidothion (847)+TX, vaniliprole [CCN]+TX, veratridine (alternative name) (725)+TX, veratrine (alternative name) (725)+TX, XMC (853)+TX, xylylcarb (854)+TX, yl-5302 (compound code)+TX, zeta-cypermethrin (205)+TX, zetamethrin (alternative name)+TX, zinc phosphide (640)+TX, zolaprofos (1469) and ZXI 8901 (development code) (858)+TX, cyantraniliprole [736994-63-19]+TX, chlorantraniliprole [500008-45-7]+TX, cyenopyrafen [560121-52-0]+TX, cyflumetofen [400882-07-7]+TX, pyrifluquinazon [337458-27-2]+TX, spinetoram [187166-40-1+187166-15-0]+TX, spirotetramat [203313-25-1]+TX, sulfoxaflor [946578-00-3]+TX, flufiprole [704886-18-0]+TX, meperfluthrin [915288-13-0]+TX, tetramethylfluthrin [84937-88-2]+TX,
 
a molluscicide selected from the group of substances consisting of bis(tributyltin) oxide (IUPAC name) (913)+TX, bromoacetamide [CCN]+TX, calcium arsenate [CCN]+TX, cloethocarb (999)+TX, copper acetoarsenite [CCN]+TX, copper sulfate (172)+TX, fentin (347)+TX, ferric phosphate (IUPAC name) (352)+TX, metaldehyde (518)+TX, methiocarb (530)+TX, niclosamide (576)+TX, niclosamide-olamine (576)+TX, pentachlorophenol (623)+TX, sodium pentachlorophenoxide (623)+TX, tazimcarb (1412)+TX, thiodicarb (799)+TX, tributyltin oxide (913)+TX, trifenmorph (1454)+TX, trimethacarb (840)+TX, triphenyltin acetate (IUPAC name) (347) and triphenyltin hydroxide (IUPAC name) (347)+TX, pyriprole [394730-71-3]+TX,
 
a nematicide selected from the group of substances consisting of AKD-3088 (compound code)+TX, 1,2-dibromo-3-chloropropane (IUPAC/Chemical Abstracts name) (1045)+TX, 1,2-dichloropropane (IUPAC/Chemical Abstracts name) (1062)+TX, 1,2-dichloropropane with 1,3-dichloropropene (IUPAC name) (1063)+TX, 1,3-dichloropropene (233)+TX, 3,4-dichlorotetrahydrothiophene 1,1-dioxide (IUPAC/Chemical Abstracts name) (1065)+TX, 3-(4-chlorophenyl)-5-methylrhodanine (IUPAC name) (980)+TX, 5-methyl-6-thioxo-1,3,5-thiadiazinan-3-ylacetic acid (IUPAC name) (1286)+TX, 6-isopentenylaminopurine (alternative name) (210)+TX, abamectin (1)+TX, acetoprole [CCN]+TX, alanycarb (15)+TX, aldicarb (16)+TX, aldoxycarb (863)+TX, AZ 60541 (compound code)+TX, benclothiaz [CCN]+TX, benomyl (62)+TX, butylpyridaben (alternative name)+TX, cadusafos (109)+TX, carbofuran (118)+TX, carbon disulfide (945)+TX, carbosulfan (119)+TX, chloropicrin (141)+TX, chlorpyrifos (145)+TX, cloethocarb (999)+TX, cytokinins (alternative name) (210)+TX, dazomet (216)+TX, DBCP (1045)+TX, DCIP (218)+TX, diamidafos (1044)+TX, dichlofenthion (1051)+TX, dicliphos (alternative name)+TX, dimethoate (262)+TX, doramectin (alternative name) [CCN]+TX, emamectin (291)+TX, emamectin benzoate (291)+TX, eprinomectin (alternative name) [CCN]+TX, ethoprophos (312)+TX, ethylene dibromide (316)+TX, fenamiphos (326)+TX, fenpyrad (alternative name)+TX, fensulfothion (1158)+TX, fosthiazate (408)+TX, fosthietan (1196)+TX, furfural (alternative name) [CCN]+TX, GY-81 (development code) (423)+TX, heterophos [CCN]+TX, iodomethane (IUPAC name) (542)+TX, isamidofos (1230)+TX, isazofos (1231)+TX, ivermectin (alternative name) [CCN]+TX, kinetin (alternative name) (210)+TX, mecarphon (1258)+TX, metam (519)+TX, metam-potassium (alternative name) (519)+TX, metam-sodium (519)+TX, methyl bromide (537)+TX, methyl isothiocyanate (543)+TX, milbemycin oxime (alternative name) [CCN]+TX, moxidectin (alternative name) [CCN]+TX,  Myrothecium verrucaria  composition (alternative name) (565)+TX, NC-184 (compound code)+TX, oxamyl (602)+TX, phorate (636)+TX, phosphamidon (639)+TX, phosphocarb [CCN]+TX, sebufos (alternative name)+TX, selamectin (alternative name) [CCN]+TX, spinosad (737)+TX, terbam (alternative name)+TX, terbufos (773)+TX, tetrachlorothiophene (IUPAC/Chemical Abstracts name) (1422)+TX, thiafenox (alternative name)+TX, thionazin (1434)+TX, triazophos (820)+TX, triazuron (alternative name)+TX, xylenols [CCN]+TX, yl-5302 (compound code) and zeatin (alternative name) (210)+TX, fluensulfone [318290-98-1]+TX,
 
a nitrification inhibitor selected from the group of substances consisting of potassium ethylxanthate [CCN] and nitrapyrin (580)+TX,
 
a plant activator selected from the group of substances consisting of acibenzolar (6)+TX, acibenzolar-S-methyl (6)+TX, probenazole (658) and  Reynoutria sachalinensis  extract (alternative name) (720)+TX,
 
a rodenticide selected from the group of substances consisting of 2-isovalerylindan-1,3-dione (IUPAC name) (1246)+TX, 4-(quinoxalin-2-ylamino)benzenesulfonamide (IUPAC name) (748)+TX, alpha-chlorohydrin [CCN]+TX, aluminium phosphide (640)+TX, antu (880)+TX, arsenous oxide (882)+TX, barium carbonate (891)+TX, bisthiosemi (912)+TX, brodifacoum (89)+TX, bromadiolone (91)+TX, bromethalin (92)+TX, calcium cyanide (444)+TX, chloralose (127)+TX, chlorophacinone (140)+TX, cholecalciferol (alternative name) (850)+TX, coumachlor (1004)+TX, coumafuryl (1005)+TX, coumatetralyl (175)+TX, crimidine (1009)+TX, difenacoum (246)+TX, difethialone (249)+TX, diphacinone (273)+TX, ergocalciferol (301)+TX, flocoumafen (357)+TX, fluoroacetamide (379)+TX, flupropadine (1183)+TX, flupropadine hydrochloride (1183)+TX, gamma-HCH (430)+TX, HCH (430)+TX, hydrogen cyanide (444)+TX, iodomethane (IUPAC name) (542)+TX, lindane (430)+TX, magnesium phosphide (IUPAC name) (640)+TX, methyl bromide (537)+TX, norbormide (1318)+TX, phosacetim (1336)+TX, phosphine (IUPAC name) (640)+TX, phosphorus [CCN]+TX, pindone (1341)+TX, potassium arsenite [CCN]+TX, pyrinuron (1371)+TX, scilliroside (1390)+TX, sodium arsenite [CCN]+TX, sodium cyanide (444)+TX, sodium fluoroacetate (735)+TX, strychnine (745)+TX, thallium sulfate [CCN]+TX, warfarin (851) and zinc phosphide (640)+TX,
 
a synergist selected from the group of substances consisting of 2-(2-butoxyethoxy)ethyl piperonylate (IUPAC name) (934)+TX, 5-(1,3-benzodioxol-5-yl)-3-hexylcyclohex-2-enone (IUPAC name) (903)+TX, farnesol with nerolidol (alternative name) (324)+TX, MB-599 (development code) (498)+TX, MGK 264 (development code) (296)+TX, piperonyl butoxide (649)+TX, piprotal (1343)+TX, propyl isomer (1358)+TX, 5421 (development code) (724)+TX, sesamex (1393)+TX, sesasmolin (1394) and sulfoxide (1406)+TX,
 
an animal repellent selected from the group of substances consisting of anthraquinone (32)+TX, chloralose (127)+TX, copper naphthenate [CCN]+TX, copper oxychloride (171)+TX, diazinon (227)+TX, dicyclopentadiene (chemical name) (1069)+TX, guazatine (422)+TX, guazatine acetates (422)+TX, methiocarb (530)+TX, pyridin-4-amine (IUPAC name) (23)+TX, thiram (804)+TX, trimethacarb (840)+TX, zinc naphthenate [CCN] and ziram (856)+TX,
 
a virucide selected from the group of substances consisting of imanin (alternative name) [CCN] and ribavirin (alternative name) [CCN]+TX,
 
a wound protectant selected from the group of substances consisting of mercuric oxide (512)+TX, octhilinone (590) and thiophanate-methyl (802)+TX,
 
and biologically active compounds selected from the group consisting of azaconazole (60207-31-0]+TX, bitertanol [70585-36-3]+TX, bromuconazole [116255-48-2]+TX, cyproconazole [94361-06-5]+TX, difenoconazole [119446-68-3]+TX, diniconazole [83657-24-3]+TX, epoxiconazole [106325-08-0]+TX, fenbuconazole [114369-43-6]+TX, fluquinconazole [136426-54-5]+TX, flusilazole [85509-19-9]+TX, flutriafol [76674-21-0]+TX, hexaconazole [79983-71-4]+TX, imazalil [35554-44-0]+TX, imibenconazole [86598-92-7]+TX, ipconazole [125225-28-7]+TX, metconazole [125116-23-6]+TX, myclobutanil [88671-89-0]+TX, pefurazoate [101903-30-4]+TX, penconazole [66246-88-6]+TX, prothioconazole [178928-70-6]+TX, pyrifenox [88283-41-4]+TX, prochloraz [67747-09-5]+TX, propiconazole [60207-90-1]+TX, simeconazole [149508-90-7]+TX, tebuconazole [107534-96-3]+TX, tetraconazole [112281-77-3]+TX, triadimefon [43121-43-3]+TX, triadimenol [55219-65-3]+TX, triflumizole [99387-89-0]+TX, triticonazole [131983-72-7]+TX, ancymidol [12771-68-5]+TX, fenarimol [60168-88-9]+TX, nuarimol [63284-71-9]+TX, bupirimate [41483-43-6]+TX, dimethirimol [5221-53-4]+TX, ethirimol [23947-60-6]+TX, dodemorph [1593-77-7]+TX, fenpropidine [67306-00-7]+TX, fenpropimorph [67564-91-4]+TX, spiroxamine [118134-30-8]+TX, tridemorph [81412-43-3]+TX, cyprodinil [121552-61-2]+TX, mepanipyrim [110235-47-7]+TX, pyrimethanil [53112-28-0]+TX, fenpiclonil [74738-17-3]+TX, fludioxonil [131341-86-1]+TX, benalaxyl [71626-11-4]+TX, furalaxyl [57646-30-7]+TX, metalaxyl [57837-19-1]+TX, R-metalaxyl [70630-17-0]+TX, ofurace [58810-48-3]+TX, oxadixyl [77732-09-3]+TX, benomyl [17804-35-2]+TX, carbendazim [10605-21-7]+TX, debacarb [62732-91-6]+TX, fuberidazole [3878-19-1]+TX, thiabendazole [148-79-8]+TX, chlozolinate [84332-86-5]+TX, dichlozoline [24201-58-9]+TX, iprodione [36734-19-7]+TX, myclozoline [54864-61-8]+TX, procymidone [32809-16-8]+TX, vinclozoline [50471-44-8]+TX, boscalid [188425-85-6]+TX, carboxin [5234-68-4]+TX, fenfuram [24691-80-3]+TX, flutolanil [66332-96-5]+TX, mepronil [55814-41-0]+TX, oxycarboxin [5259-88-1]+TX, penthiopyrad [183675-82-3]+TX, thifluzamide [130000-40-7]+TX, guazatine [108173-90-6]+TX, dodine [2439-10-3] [112-65-2] (free base)+TX, iminoctadine [13516-27-3]+TX, azoxystrobin [131860-33-8]+TX, dimoxystrobin [149961-52-4]+TX, enestroburin {Proc. BCPC, Int. Congr., Glasgow, 2003, 1, 93}+TX, fluoxastrobin [361377-29-9]+TX, kresoxim-methyl [143390-89-0]+TX, metomi-nostrobin [133408-50-1]+TX, trifloxystrobin [141517-21-7]+TX, orysastrobin [248593-16-0]+TX, picoxystrobin [117428-22-5]+TX, pyraclostrobin [175013-18-0]+TX, ferbam [14484-64-1]+TX, mancozeb [8018-01-7]+TX, maneb [12427-38-2]+TX, metiram [9006-42-2]+TX, propineb [12071-83-9]+TX, thiram [137-26-8]+TX, zineb [12122-67-7]+TX, ziram [137-30-4]+TX, captafol [2425-06-1]+TX, captan [133-06-2]+TX, dichlofluanid [1085-98-9]+TX, fluoroimide [41205-21-4]+TX, folpet [133-07-3]+TX, tolylfluanid [731-27-1]+TX, bordeaux mixture [8011-63-0]+TX, copperhydroxid [20427-59-2]+TX, copperoxychlorid [1332-40-7]+TX, coppersulfat [7758-98-7]+TX, copperoxid [1317-39-1]+TX, mancopper [53988-93-5]+TX, oxine-copper [10380-28-6]+TX, dinocap [131-72-6]+TX, nitrothal-isopropyl [10552-74-6]+TX, edifenphos [17109-49-8]+TX, iprobenphos [26087-47-8]+TX, isoprothiolane [50512-35-1]+TX, phosdiphen [36519-00-3]+TX, pyrazophos [13457-18-6]+TX, tolclofos-methyl [57018-04-9]+TX, acibenzolar-S-methyl [135158-54-2]+TX, anilazine [101-05-3]+TX, benthiavalicarb [413615-35-7]+TX, blasticidin-S [2079-00-7]+TX, chinomethionat [2439-01-2]+TX, chloroneb [2675-77-6]+TX, chlorothalonil [1897-45-6]+TX, cyflufenamid [180409-60-3]+TX, cymoxanil [57966-95-7]+TX, dichlone [117-80-6]+TX, diclocymet [139920-32-4]+TX, diclomezine [62865-36-5]+TX, dicloran [99-30-9]+TX, diethofencarb [87130-20-9]+TX, dimethomorph [110488-70-5]+TX, SYP-LI90 (Flumorph) [211867-47-9]+TX, dithianon [3347-22-6]+TX, ethaboxam [162650-77-3]+TX, etridiazole [2593-15-9]+TX, famoxadone [131807-57-3]+TX, fenamidone [161326-34-7]+TX, fenoxanil [115852-48-7]+TX, fentin [668-34-8]+TX, ferimzone [89269-64-7]+TX, fluazinam [79622-59-6]+TX, fluopicolide [239110-15-7]+TX, flusulfamide [106917-52-6]+TX, fenhexamid [126833-17-8]+TX, fosetyl-aluminium [39148-24-8]+TX, hymexazol [10004-44-1]+TX, iprovalicarb [140923-17-7]+TX, IKF-916 (Cyazofamid) [120116-88-3]+TX, kasugamycin [6980-18-3]+TX, methasulfocarb [66952-49-6]+TX, metrafenone [220899-03-6]+TX, pencycuron [66063-05-6]+TX, phthalide [27355-22-2]+TX, polyoxins [11113-80-7]+TX, probenazole [27605-76-1]+TX, propamocarb [25606-41-1]+TX, proquinazid [189278-12-4]+TX, pyroquilon [57369-32-1]+TX, quinoxyfen [124495-18-7]+TX, quintozene [82-68-8]+TX, sulphur [7704-34-9]+TX, tiadinil [223580-51-6]+TX, triazoxide [72459-58-6]+TX, tricyclazole [41814-78-2]+TX, triforine [26644-46-2]+TX, validamycin [37248-47-8]+TX, zoxamide (RH7281) [156052-68-5]+TX, mandipropamid [374726-62-2]+TX, isopyrazam [881685-58-1]+TX, sedaxane [874967-67-6]+TX, 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid (9-dichloromethylene-1,2,3,4-tetrahydro-1,4-methano-naphthalen-5-yl)-amide (dislosed in WO 2007/048556)+TX, 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid [2-(2,4-dichlorophenyl)-2-methoxy-1-methyl-ethyl]-amide (disclosed in WO 2008/148570)+TX, 1-[4-[4-[(5S) 5 -(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazol-2-yl]piperidin-1-yl]-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]ethanone+TX, 1-[4-[4-[5-(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazol-2-yl]piperidin-1-yl]-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]ethanone [1003318-67-9], both disclosed in WO 2010/123791, WO 2008/013925, WO 2008/013622 and WO 2011/051243 page 20)+TX, S)-[3-(4-Chloro-2-fluoro-phenyl)-5-(2,4-difluoro-phenyl)-isoxazol-4-yl]-pyridin-3-yl-methanol+TX, 3-(4-Chloro-2-fluoro-phenyl)-5-(2,4-difluoro-phenyl)-isoxazol-4-yl]-pyridin-3-yl-methanol+TX and 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid (3′,4′,5′-trifluoro-biphenyl-2-yl)-amide (dislosed in WO 2006/087343)+TX, 3-(difluoromethyl)-N-methoxy-1-methyl-N-[1-methyl-2-(2,4,6-trichlorophenyl)ethyl]-1H-Pyrazole-4-carboxamide+TX,
 
     The mixing partners of the TX may also be in the form of esters or salts, as mentioned e.g. in The Pesticide Manual, 12th Edition (BCPC), 2000. 
     In the above different lists of active ingredients to be mixed with a TX, the compound of the formula I is preferably a compound selected from the Tables 1 to 12, A, B, C and D; more preferably; and even more preferably a compound selected from the Tables 1 to 12, A and B; a compound TX is selected from Table A, or a compound TX is selected from Table B, or a compound TX is selected from Table C, or a compound TX is selected from Table D and most preferably a compound TX is selected from A1, A3, A4, A5, A6, A8, A9, A10, All, A13, A15, A16, A17, A22, A23, A25, A28, A30, A31, A32, A33 to A36, A38 to A40, A45 to A51, A76, A56, A59, A77, A80, A82, A84, A85, A86, A87, A90, A91, A93, A94, A99, A101, A104, A105, A106, A111, A112, A115, A120, A122, A124, A126, A128, A129, A131, A132, 133, A134, A135, A136, A137, A138, A143, A144, A145, B1, B2, B3, B4, B5, B6, B7, B8, B9 and B10; or a compound TX is selected from A1, A2, A3, A4, A5, A8, A9, A10, All, A13, A14, A15, A16, A17, A19, A20, A22, A23, A25, A30, A31, A32, A33, A34, A36, A37, A38, A39, A40, A41, A42, A45, A46, A47, A48, A49, A50, A51, A76, A56, A57, A59, A61, A65, A68, A69, A72, A82, A86, A90, A101, A112, A115, A126, A128, A129, A130, A131, A132, 133, A134, A135, A136, A137, A138, A139, A140, A142, A143, A144, A145, A146, A147, A149, A151, A157, A158, A159, A167, A168, A178, A180, A181, A182, A183, A184, A186, A187, A188, A189, A190, A192, A195, A196, A197, A198, A199, B1, B2, B3, B4, B5, B6, B7, B8, B9 and B10; or a compound TX is selected from A1, A3, A4, A5, A6, A10, A12, A13, A15, A22, A23, A25, A28, A31, A32, A33, A34, A35, A36, A38, A39, A40, A41, A42, A45, A46, A48, A49, A50, A51, A76, A56, A57, A59, A61, A79, A80, A83, A84, A86, A87, A90, A91, A93, A94, A95, A104, A106, A111, A112, A123, A126, A128, A129, A130, A131, A132, 133, A134, A135, A136, A137, A138, A142, A143, A144, A145, A146, A151, A157, A159, A163, A168, A178, A181, A182, A183, A184, A188, A189, A192, A195, A197, A199, B1, B2, B3, B4, B5, B6, B7, B8, B9 and B10; or a compound TX is selected from A1, A2, A3, A4, A5, A6, A10, All, A12, A23, A30, A32, A33, A34, A35, A38, A39, A40, A42, A45, A46, A48, A49, A51, A76, A56, A57, A59, A61, A65, A68, A69, A80, A81, A82, A84, A87, A93, A101, A106, A109, A112, A115, A124, A126, A128, A129, A131, A132, 133, A134, A135, A136, A137, A138, A143, A144, A145, A146, A151, A157, A158, A159, A168, A175, A178, A180, A181, A182, A183, A184, A188, A189, A190, A191, A192, A195, A197, A198, A199, B1, B2, B3, B4, B5, B6, B7, B8 and B9; or a compound TX is selected from A1, A3, A4, A5, A6, A31, A45, A46, A48, A49, A76, A80, A81, A82, A86, A90, A100, A101, A109, A110, A115, A124, A126, A128, A129, A132, A136, A143, A144, A145, B3, B4, B5, B6, B7, B9 and B10; or A6 or a compound TX is selected from A4, A5, A10, All, A23, A25, A33, A34, A36, A40, A42, A45, A46, A48, A49, A50, A56, A80, A82, A84, A86, A94, A100, A101, A111, A112, A124, A126, A128, A132, A134, A137, A143, A168, B1, B2, B3, B4, B5, B6 and B9; or a compound TX is selected from A46, A128, A132, A135, A137, B1, B2, B3, B4, B5, B9 and B10. 
     In the above-mentioned mixtures of compounds of formula I, in particular a compound selected from said Tables 1 to 12, A, B, C and D, with other insecticides, fungicides, herbicides, safeners, adjuvants and the like, the mixing ratios can vary over a large range and are, preferably 
     100:1 to 1:6000, especially 50:1 to 1:50, more especially 20:1 to 1:20, even more especially 10:1 to 1:10. Those mixing ratios are understood to include, on the one hand, to ratios by weight and also, on other hand, molar ratios. 
     The mixtures can advantageously be used in the above-mentioned formulations (in which case “active ingredient” relates to the respective mixture of TX with the mixing partner). 
     Some mixtures may comprise active ingredients which have significantly different physical, chemical or biological properties such that they do not easily lend themselves to the same conventional formulation type. In these circumstances other formulation types may be prepared. For example, where one active ingredient is a water insoluble solid and the other a water insoluble liquid, it may nevertheless be possible to disperse each active ingredient in the same continuous aqueous phase by dispersing the solid active ingredient as a suspension (using a preparation analogous to that of an SC) but dispersing the liquid active ingredient as an emulsion (using a preparation analogous to that of an EW). The resultant composition is a suspoemulsion (SE) formulation. 
     The mixtures comprising a TX selected from Tables 1 to 12, A, B and C and one or more active ingredients as described above can be applied, for example, in a single “ready-mix” form, in a combined spray mixture composed from separate formulations of the single active ingredient components, such as a “tank-mix”, and in a combined use of the single active ingredients when applied in a sequential manner, i.e. one after the other with a reasonably short period, such as a few hours or days. The order of applying the compounds of formula I selected from Tables 1 to 12, A, B and C and the active ingredients as described above is not essential for working the present invention. 
     The compounds of formula (I) may be mixed with soil, peat or other rooting media for the protection of plants against seed-borne, soil-borne or foliar fungal diseases. 
     Examples of suitable synergists for use in the compositions include piperonyl butoxide, sesamex, safroxan and dodecyl imidazole. 
     Suitable herbicides and plant-growth regulators for inclusion in the compositions will depend upon the intended target and the effect required. 
     An example of a rice selective herbicide which may be included is propanil. An example of a plant growth regulator for use in cotton is PIX™. 
     Some mixtures may comprise active ingredients which have significantly different physical, chemical or biological properties such that they do not easily lend themselves to the same conventional formulation type. In these circumstances other formulation types may be prepared. For example, where one active ingredient is a water insoluble solid and the other a water insoluble liquid, it may nevertheless be possible to disperse each active ingredient in the same continuous aqueous phase by dispersing the solid active ingredient as a suspension (using a preparation analogous to that of an SC) but dispersing the liquid active ingredient as an emulsion (using a preparation analogous to that of an EW). The resultant composition is a suspoemulsion (SE) formulation. 
    
    
     PREPARATION OF EXAMPLES 
     Intermediate I1: 5-Azido-1-methyl-3-pentafluoroethyl-4-trifluoromethyl-1H-pyrazole 
     
       
         
         
             
             
         
       
     
     5-Fluoro-1-methyl-3-pentafluoroethyl-4-trifluoromethyl-1H-pyrazole (prepared according to Russian Chemical Bulletin 1990, 39, No. 11, p 2338; 2 g; 7 mmol) was added to a mixture of DMSO (10 ml) and sodium azide (0.5 g; 7.7 mmol) was added into the mixture, which was kept at room temperature. The mixture was stirred overnight at RT. After the reaction was complete, a mixture of water (100 mL) and diethyl ether (100 mL) was additionned. The phases were separated and the aqueous phase was extracted twice with diethyl ether. This compound was used without extra purification. 
     Intermediate I2: D1: 3-[1-(2-Methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenylamine 
     
       
         
         
             
             
         
       
     
     Ethynylaniline (comercialy available) and 5-Azido-1-methyl-3-pentafluoroethyl-4-trifluoromethyl-1H-pyrazole (Intermediate I1, 0.81 g, 2.6 mmol) were suspended in a mixture of water and t-BuOH (15 mL). Sodium ascorbate (0.300 ml 1 M sol. in water, freshly prepared) was added to the mixture followed by copper (II) sulfate pentahydrate (7 mg). The resulting heterogeneous mixture was stirred vigorously for 96 hours. The reaction mixture was diluted with water and the product was extracted with ethyl acetate. The organic phase was washed with brine, dried over magnesium sulphate and evaporated. The resisue was subjected to silica gel column chromatography (iHEX/EtOAc=3:1) affording the desired product 3-[1-(2-Methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenylamine (Compound D1).  1 H NMR (400 MHz, CDCl 3 ): 8.01 (s, 1H), 7.32-7.19 (m, 2H), 6.75 (dd, 1H), 3.39 (s, 3H), 3.81 (s, 2H) ppm. 
     2-Fluoro-3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenylamine (Compound D4) was prepared by the same method using 3-ethynyl-2-fluoro-phenylamine as starting material.  1 H NMR (400 MHz, CDCl 3 ): 8.26 (d, 1H), 7.73 (t, 1H), 7.14 (t, 1H), 6.88 (t, 1H), 3.89 (s, 3H), 3.87 (bs, 2H) ppm. 
     Intermediate I3: 4-Ethynyl-2-nitro-benzonitrile 
     
       
         
         
             
             
         
       
     
     A solution of 25 mL of 4-Bromo-2-nitrobenzonitrile (110.1 mmol), 25.2 ml of ethynyltrimethylsilane (178.4 mmol), 0.49 g of palladium(II) acetate (2.2 mmol), and 1.16 g of triphenylphosphine (4.4 mmol) in 300 mL of anhydrous triethylamine was rapidly heated to reflux under argon overnight. The mixture was cooled and the crystalline white solid of triethylamine hydrobromide was isolated by filtration. The dark brown filtrate was concentrated, mixed with 250 mL of aqueous sodium bicarbonate, and extracted with dichloromethane (3×100 ml). The organic fractions were combined, dried over magnesium sulfate, and concentrated to yield an oil, which was dissolved in 200 ml of THF and treated with 300 ml of methanol and 450 mg of potassium carbonate. The mixture was stirred for 1 hour and concentrated. The concentrated solution was mixed with 250 mL of aqueous sodium bicarbonate, and extracted with ethyl acetate (3×100 ml). The organic fractions were combined, dried over magnesium sulfate, and concentrated in vacuo, and chromatographed with cyclohexane/ethyl acetate (95:5) to give 4-Ethynyl-2-nitro-benzonitrile (7.3 g, 39% yield).  1 H NMR (400 MHz, CDCl 3 ): 8.40 (s, 1H), 7.89 (s, 2H), 3.5 (s, 1H) ppm. 
     Intermediate I4: C1: 4-[1-(2-Methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]-triazol-4-yl]-2-nitro-benzonitrile 
     
       
         
         
             
             
         
       
     
     4-Ethynyl-2-nitro-benzonitrile (1.20 g, 1.07 mmol) and 5-Azido-1-methyl-3-pentafluoroethyl-4-trifluoromethyl-1H-pyrazole (Intermediate I1, 2.15 g, 7.0 mmol) were suspended in a mixture of water and t-BuOH (1:1, 30 mL). Sodium ascorbate (0.3 ml, 1 M sol. In water, freshly prepared) was added to the mixture followed by copper (II) sulfate pentahydrate (0.017 g). The resulting heterogeneous mixture was stirred vigorously at room temperature for 96 hours. The reaction mixture was diluted with water and cooled in an ice bath. The orange product which precipited was filtered and dried. The residue was subjected to silica gel column chromatography (ethyl acetate:cyclohexane 1:3) affording the desired product (Compound C1) (1.3 g, 40% yield).  1 H NMR (400 MHz, CDCl 3 ): 8.82 (s, 1H), 8.41 (d, 1H), 8.33 (s, 1H), 8.07 (d, 1H), 3.92 (s, 3H) ppm. 
     4-(4-chloro-3-nitro-phenyl)-1-[2-methyl-5-(1,1,2,2,2-pentafluoroethyl)-4-(trifluoromethyl) pyrazol-3-yl]triazole was prepared by the same method using 1-chloro-4-ethynyl-2-nitro-benzene (111aphthalene111 available) as starting material.  1 H NMR (400 MHz, CDCl 3 ): 8.40 (d, 1H), 8.23 (s, 1H), 8.10 (dd, 1H), 7.71 (d, 1H), 3.81 (s, 3H) ppm. 
     Intermediate I5: D2: 2-Amino-4-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-benzonitrile 
     
       
         
         
             
             
         
       
     
     To a solution of 4-[1-(2-Methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-2-nitro-benzonitrile (Intermediate I5) (1.35 g, 2.8 mmol) in tetrahydrofuran (37.5 ml) was added aqueous sodium hydroxide (0.1 M) (12.5 ml), sodium hydrosulfite (82%, 2.98 g, 14.0 mmol) and tetrabutylammonium bromide (“TBAB”) (0.09 g, 0.3 mmol). The reaction mixture was stirred at ambient temperature for 2 hours. The mixture of water (100 mL) and ethyl acetate (100 mL) was added. The aqueous and organic phases were separated. The aqueous phase was extracted twice with ethyl acetate. The combined organic extracts were dried over sodium sulfate and concentrated. The residue was purified by filtration on silica gel to give 2-Amino-4-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-benzonitrile (Compound D2) (1.22 g, 96% yield).  1 H NMR (400 MHz, CDCl 3 ): 8.12 (s, 1H), 7.52 (d, 1H), 7.41 (s, 1H), 7.19 (d, 1H), 4.58 (sb, 2H), 3.88 (s, 3H) ppm. 
     2-Methoxy-3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenylamine (Compound D5) from table D was prepared by the same method using 4-(2-methoxy-3-nitro-phenyl)-1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazole as starting material.  1 H NMR (400 MHz, CDCl 3 ): 8.4 (s, 1H), 7.68 (d, 1H), 7.11 (t, 1H), 6.83 (t, 1H), 3.92 (bs, 2H+3H), 3.71 (s, 3H) ppm. 
     Intermediate I6: D3: 2-chloro-5-[1-[2-methyl-5-(1,1,2,2,2-pentafluoroethyl)-4-(trifluoromethyl)pyrazol-3-yl]triazol-4-yl]aniline 
     
       
         
         
             
             
         
       
     
     To a solution of 4-(4-chloro-3-nitro-phenyl)-1-[2-methyl-5-(1,1,2,2,2-pentafluoroethyl)-4-(trifluoromethyl)pyrazol-3-yl]triazole (Example 14) (0.90 g, 1.8 mmol) in isopropanol (6 ml) was added tin chloride (1.5 g, 6.6 mmol) at ambient temperature. The mixture was cooled to 0° C. and concentrated aqueous hydrochloric acid (1.5 ml) was added slowly. The reaction mixture was stirred at 80° C. for 2 hours. One third of the total volume of isopropanol was evaporated. Water (100 ml) was added to the concentrated mixture and aqueous sodium hydroxide (30%) was added to adjust the pH to 8 to 9. The aqueous phase was extracted three times with ethyl acetate (3×200 ml). The combined organic extracts were dried over sodium sulfate and concentrated. The residue was purified by column chromatography on silica gel (eluent: cyclohexane/ethyl acetate 2:1 to 1:1) to give 2-chloro-5-[1-[2-methyl-5-(1,1,2,2,2-pentafluoroethyl)-4-(trifluoromethyl)pyrazol-3-yl]triazol-4-yl]aniline (Compound D3) (0.67 g, 79% yield). 
       1 H NMR (400 MHz, CDCl 3 ): 8.01 (s, 1H), 7.40 (d, 1H), 7.35 (d, 1H), 7.14 (dd, 1H), 4.23 (bs, 2H), 3.87 (s, 3H) ppm. 
     Example I 17.1 
     D6: Ethyl-{2-fluoro-3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenyl}-amine 
     
       
         
         
             
             
         
       
     
     2-fluoro-3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenylamine (Compound D4) (0.200 g, 0.45 mmol) was dissolved in methanol (8 ml) and acetaldehyde (0.027 ml, 0.47 mmol) and acetic acid (0.03 ml, 0.54 mmol) were added. Then cyanoborohydride (0.0368 g, 0.585 mmol) was added in small portions. The reaction mixture was stirred for 1.2 hours at room temperature. The mixture was diluted with aqueous sodium bicarbonate and the aqueous layer was extracted twice with ethyl acetate. The combined organic layers were dried over sodium sulfate, filtered and concentrated. The residue was purified by chromatography (eluent: cyclohexane/ethyl acetate) to give ethyl-{2-fluoro-3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenyl}-amine (Compound D6) (0.170 g, 80%). 
       1 H NMR (400 MHz, CDCl 3 ): 8.21 (d, 1H), 7.72 (t, 1H), 7.19 (t, 1H), 6.29 (t, 1H), 3.93 (bs, 1H), 3.88 (s, 3H), 3.27 (q, 2H), 1.34 (t, 3H) ppm. 
     {2-Methoxy-3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl) 1H[1,2,3]triazol-4-yl]-phenyl}-methylamine (Compound D7) from table D was prepared by a similar procedure using 2-methoxy-3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenylamine (Compound D5) as a starting material and formaldehyde in water (˜37.3 mass %) as a reagent: 
       1 H NMR (400 MHz, CDCl 3 ): 8.48 (s, 1H), 7.61 (dd, 1H), 7.22 (t, 1H), 6.73 (dd, 1H), 4.32 (bs, 1H), 3.92 (s, 3H), 3.68 (s, 3H), 2.92 (s, 3H) ppm. 
     Example P1 
     4-Cyano-N-{2-cyano-5-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenyl}-2-methyl-benzamide (Compound A1) 
     
       
         
         
             
             
         
       
     
     A solution of 2-Amino-4-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-benzonitrile (Compound D2) in tetrahydrofurane (5 mL) was successively added 2-methyl-4-cyanobenzoyl chloride (0.1 g, 0.5 mmol, 2 eq.) and pyridine (0.064 mL, 0.8 eq). The mixture was stirred overnight at RT. Then, the mixture was dissolved in a mixture of ethyl acetate and water. The organic layer and the aqueous layer were separated, then the aqueous phase was extracted 2 time with ethyl acetate. The organic phase was combinated and dried with sodium sulfate and the solvent was evaporated in vacuo. The residue was purified by column chromatography (cyclohexane:ethyl acetate:3:1) to give 4-Cyano-N-{2-cyano-5-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenyl}-2-methyl-benzamide (Compound A1) (0.1 g, 63% yield).  1 H NMR (400 MHz, CDCl 3 ): 9.05 (s, 1H), 8.30 (s, 1H), 8.03 (s, 1H), 7.97 (d, 1H), 7.81 (d, 1H), 7.70 (d, 1H), 7.64 (m, 2H), 3.89 (s, 3H), 2.60 (s, 3H) ppm. 
     Compounds A2 to A6 and A76, A126 to A131, 133 to 141 from table A and B1 to B8 from table B were prepared by the same or similar method using 2-amino-4-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-benzonitrile (Compound D2) or 3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenylamine (Compound C1) or 2-chloro-5-[1-[2-methyl-5-(1,1,2,2,2-pentafluoroethyl)-4-(trifluoromethyl)pyrazol-3-yl]triazol-4-yl]aniline (Compound D3) or 2-fluoro-3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoro-methyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenylamine (Compound D4) or 2-methoxy-3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenylamine (Compound D5) or ethyl-{2-fluoro-3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenyl}-amine (Compound D6) or {2-methoxy-3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl) 1H[1,2,3]triazol-4-yl]-phenyl}-methylamine (Compound D7) as starting material. 
     Example P2 
     General Method for the Acylation of an Amino-Benzamide in Parallel 
     
       
         
         
             
             
         
       
     
     Solution A was prepared by dissolving an amino-benzamide (0.78 mmol), e.g. 3-[1-(2-Methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenylamine (Compound D1) in the case of compound A7 of Table A, in toluene (15.6 ml). Solution B was prepared by dissolving the acid chloride (1.0 mol), e.g. 2-fluoro-benzoyl chloride in the case of compound No. A7 of Table A in toluene (8 ml). 
     Solution A (0.6 ml, 30 μmol) was put in a well and solution B (0.3 ml, 36 μmol) and diisopropylethylamine (Hunig&#39;s Base) (30 μl, 150 μmol) were added successively. The mixture was stirred at 70° C. overnight. The mixture was diluted with a mixture of acetonitrile (0.6 ml) and N,N-dimethylacetamide (0.2 ml) and then purified by HPLC to give the desired compound, for example the 2-Fluoro-N-{3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenyl}-benzamide (Compound A7). 
     This general method or an analogue method was used to prepare a number of compounds (Compound No. A7 to A75, A77 to A125 and A146 to A200) of Table A using 2-Amino-4-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-benzonitrile (Compound D2) or 3-[1-(2-Methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenylamine (Compound D1) or 2-chloro-5-[1-[2-methyl-5-(pentafluoroethyl)-4-(trifluoromethyl)pyrazol-3-yl]triazol-4-yl]aniline (Compound D3) or 2-fluoro-3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenylamine (Compound D4) as starting material. 
     Example P3 
     N-{2-Fluoro-3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenyl}-1-oxy-isonicotinamide (Compound A132) 
     
       
         
         
             
             
         
       
     
     N-{2-Fluoro-3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenyl}-isonicotinamide (Compound A128) (0.050 g, 0.1125 mmol) was dissolved in dichloromethane (2 ml) and 3-chloroperoxybenzoic acid (0.0261 g, 0.1463 mmol) was added. After stirring for 4 h at room temperature the mixture was diluted with dichloromethane and an aqueous solution of sodium hydroxide was added. The phases were separated the organic phase was washed with brine, dried over sodium sulfate, filtered and concentrated to give pure Compound A132 (50 mg, 79% yield). M.p. 227-229° C.  1 H NMR (400 MHz, CDCl 3 ): 8.44 (t, 1H), 8.22 (d, 2H), 8.17 (d, 1H), 8.09 (t, 1H), 7.97 (bs, 1H), 7.71 (d, 2H), 7.32 (t, 1H), 3.82 (s, 3H) ppm. 
     Compounds A142 to A143 of table A and B9 to B10 of table B were prepared by the same procedure. 
     Example P4 
     2,4,6-Trifluoro-N-{2-methoxy-3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenyl}-benzamide (Compound A144) 
     
       
         
         
             
             
         
       
     
     1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDCI, 0.0429 g, 0.217 mol), 1-hydroxy-7-azabenzotriazole (HOAT, 0.0301 g, 0.217 mol), triethylamine (0.056 ml, 0.394 mmol) and 2,4,6-trifluorobenzoic acid (39 mg, 0.217 mmol) were added to a solution of 2-methoxy-3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenylamine (Compound D5) (0.09 g, 0.197 mmol) in dichloromethane (4 mL). The mixture was stirred overnight at RT (19 hours). Then, the mixture was diluted with dichloromethane and aqueous sodium bicarbonate was added. The organic layer and the aqueous layer were separated, then the organic phase was extracted with an aqueous solution of sodium hydroxide. The organic phase was dried with sodium sulfate, filtered and the solvent was evaporated in vacuo. The residue was purified by column chromatography (cyclohexane:ethyl acetate) to give 2,4,6-trifluoro-N-{2-methoxy-3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenyl}-benzamide (Compound A144) (0.038 g, 32% yield).  1 H NMR (400 MHz, CDCl 3 ): 8.49 (dd, 1H), 8.28 (s, 1H), 8.19 (bs, 1H), 7.98 (dd, 1H), 7.29 (t, 1H), 6.75 (t, 2H), 3.87 (s, 3H), 3.63 (s, 3H) ppm. 
     Compounds A145 and A201 of table A were prepared by the same procedure. 
     Example P5 
     2,4,6-Trifluoro-N-{2-methoxy-3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenyl}-N-methyl-benzamide (Compound B11) 
     
       
         
         
             
             
         
       
     
     Triethylamine (0.060 ml, 0.425 mmol), 2,4,6-trifluorobenzoic acid (46 mg, 0.255 mmol) and BOP-Cl (0.167 g, 0.638 mmol) were added to a solution of {2-methoxy-3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)1H[1,2,3]triazol-4-yl]-phenyl}-methylamine (Compound D7) (0.1 g, 0.213 mmol) in 1,2-dichloroethane (3 mL). The mixture was stirred under reflux for 15 hours. Then, the mixture was diluted with dichloromethane and aqueous sodium bicarbonate was added. The organic layer and the aqueous layer were separated, then the organic phase was extracted with brine. The organic phase was dried with sodium sulfate, filtered and the solvent was evaporated in vacuo. The residue was purified by column chromatography (cyclohexane:ethyl acetate) to give 2,4,6-trifluoro-N-{2-methoxy-3-[1-(2-methyl-5-pentafluoroethyl-4-trifluoromethyl-2H-pyrazol-3-yl)-1H-[1,2,3]triazol-4-yl]-phenyl}-N-methyl-benzamide (Compound B 11) (0.045 g, 34% yield).  1 H NMR (400 MHz, CDCl 3 ): 8.20 (d, 1H), 8.17 (s, 1H), 7.45 (d, 1H), 6.82 (t, 1H), 6.52 (bs, 1H), 6.38 (bs, 1H), 3.90 (s, 3H), 3.78 (s, 3H), 3.58 (s, 3H) ppm. In addition the spectrum contains peaks of rotational isomers. 
     Method A: 
     LC-MS Method (positive or negative) for compounds A1 to A7, C1, D1 and D2: 
     ZQ Mass Spectrometer from Waters (Single quadrupole mass spectrometer) 
     Instrument Parameter: 
     Ionization method: Electrospray 
     Polarity: positive ions 
     Capillary (kV) 3.00, Cone (V) 30.00, Extractor (V) 2.00, Source Temperature (° C.) 100, 
     Desolvation Temperature (° C.) 250, Cone Gas Flow (L/Hr) 50, Desolvation Gas Flow (L/Hr) 400 
     Mass range: 100 to 900 Da 
     HP 1100 HPLC from Agilent: solvent degasser, quaternary pump (ZCQ)/binary pump 
     (ZDQ), heated column compartment and diode-array detector. 
     Column: Phenomenex Gemini C18, 3 μm, 30×3 mm, 
     Temp: 60° C. 
     DAD Wavelength range (nm): 200 to 500 
     Solvent Gradient: 
     A=water+0.05% HCOOH 
     B=Acetonitril/Methanol (4:1, v:v)+0.04% HCOOH 
     
       
         
           
               
               
               
               
               
             
               
                   
                   
               
               
                   
                 Time 
                 A % 
                 B % 
                 Flow(ml/min) 
               
               
                   
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
            
               
                   
                 0.00 
                 95.0 
                 5.0 
                 1.700 
               
               
                   
                 2.00 
                 0.0 
                 100.0 
                 1.700 
               
               
                   
                 2.80 
                 0.0 
                 100.0 
                 1.700 
               
               
                   
                 2.90 
                 95.0 
                 5.0 
                 1.700 
               
               
                   
                 3.00 
                 95.0 
                 5.0 
                 1.700 
               
               
                   
                   
               
            
           
         
       
     
     Method B: 
     LC-MS Method (positive) for compounds A7 to A75, A77 to A125 and A146 to A200: ACQUITY SQD Mass Spectrometer from Waters (Single quadrupole mass spectrometer) Ionisation method: Electrospray, polarity: positive ions, Capillary (kV) 3.00, Cone (V) 20.00, Extractor (V) 3.00, Source Temperature (° C.) 150, Desolvation Temperature (° C.) 400, Cone Gas Flow (L/Hr) 60, Desolvation Gas Flow (L/Hr) 700 
     Mass range: 100 to 800 Da, DAD Wavelength range (nm): 210 to 400 
     Method Waters ACQUITY UPLC with the following HPLC gradient conditions 
     (Solvent A: Water/Methanol 9:1, 0.1% formic acid and Solvent B: Acetonitrile, 0.1% formic acid) 
     
       
         
           
               
               
               
               
               
             
               
                   
                   
               
               
                   
                 Time (minutes) 
                 A (%) 
                 B (%) 
                 Flow rate (ml/min) 
               
               
                   
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
            
               
                   
                 0 
                 100 
                 0 
                 0.75 
               
               
                   
                 2.5 
                 0 
                 100 
                 0.75 
               
               
                   
                 2.8 
                 0 
                 100 
                 0.75 
               
               
                   
                 3.0 
                 100 
                 0 
                 0.75 
               
               
                   
                   
               
            
           
         
       
     
     Type of column: Waters ACQUITY UPLC HSS T3; Column length: 30 mm; Internal diameter of column: 2.1 mm; Particle Size: 1.8 micron; Temperature: 60° C. 
     Method C: 
     LC-MS Method (positive/negative) for compounds A126 to A139, A141 to A145, B1 to B11, C2 to C3, D3 to D7: 
     ZQ Mass Spectrometer from Waters (Single quadrupole mass spectrometer) 
     Instrument Parameter Ionization method: Electrospray, polarity: positive and negative ions 
     Capillary: 3.00 kV, Cone: 30.00 V, Extractor: 2.00 V, Source Temperature: 100° C., 
     Desolvation Temperature: 250° C., Cone Gas Flow: 50 L/Hr, Desolvation Gas Flow: 400 
     L/Hr, Mass range: 100 to 900 Da 
     HP 1100 HPLC from Agilent: 
     Solvent degasser, binary pump, heated column compartment and diode-array detector. Column: Phenomenex Gemini C18, 3 μm, 30×3 mm, Temp: 60° C., DAD Wavelength range (nm): 210 to 500 
     Solvent Gradient:
         A=H2O+5% MeOH+0.05% HCOOH   B=Acetonitril+0.05% HCOOH       

     
       
         
           
               
               
               
               
               
             
               
                   
                   
               
               
                   
                 Time 
                 A % 
                 B % 
                 Flow(ml/min) 
               
               
                   
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
            
               
                   
                 0.00 
                 100 
                 0 
                 1.700 
               
               
                   
                 2.00 
                 0 
                 100.0 
                 1.700 
               
               
                   
                 2.80 
                 0 
                 100.0 
                 1.700 
               
               
                   
                 2.90 
                 100 
                 0 
                 1.700 
               
               
                   
                 3.00 
                 100 
                 0 
                 1.700 
               
               
                   
                   
               
            
           
         
       
     
     Method D: 
     LC-MS Method (positive/negative) for compounds A140 and A143: 
     SQD Mass Spectrometer from Waters (Single quadrupole mass spectrometer) 
     Instrument Parameter: Ionization method: Electrospray, Polarity: positive and negative ions, Capillary: 3.00 kV, Cone: 30.00 V, Extractor: 2.00 V, Source Temperature: 150° C., Desolvation Temperature: 250° C., Cone Gas Flow: 0 L/Hr, Desolvation Gas Flow: 650 L/Hr, 
     Mass range: 100 to 900 Da 
     Acquity UPLC from Waters: 
     Binary pump, heated column compartment and diode-array detector. 
     Solvent degasser, binary pump, heated column compartment and diode-array detector. 
     Column: Phenomenex Gemini C18, 3 μm, 30×2 mm, 
     Temp: 60° C. 
     DAD Wavelength range (nm): 210 to 500 
     Solvent Gradient:
         A=H2O+5% MeOH+0.05% HCOOH   B=Acetonitril+0.05% HCOOH       

     
       
         
           
               
               
               
               
               
             
               
                   
                   
               
               
                   
                 Time 
                 A % 
                 B % 
                 Flow (ml/min) 
               
               
                   
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
               
            
               
                   
                 0.00 
                 100 
                 0 
                 0.850 
               
               
                   
                 1.2 
                 0 
                 100.0 
                 0.850 
               
               
                   
                 1.50 
                 0 
                 100.0 
                 0.850 
               
               
                   
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE A 
               
             
            
               
                   
               
               
                 Compounds of formula (I′): R 1  = H, R 2  = H 
               
            
           
           
               
               
            
               
                   
                 (I′) 
               
               
                 
                   
                     
                     
                         
                         
                     
                   
                 
                   
               
               
                   
               
            
           
           
               
               
               
               
               
               
               
               
            
               
                   
                   
                   
                   
                 RT 
                   
                   
                 MP 
               
               
                 Ex. 
                 Q 1   
                 A 1   
                 A 4   
                 (min) 
                 MH +   
                 M − H +   
                 (°C.) 
               
               
                   
               
               
                 A1 
                 2-methyl-4-cyano-phenyl 
                 C—CN 
                 CH 
                 2.05 
                 — 
                 593 
                 101 
               
               
                 A2 
                 Cyclopropyl 
                 C—CN 
                 CH 
                 1.99 
                 — 
                 518 
                 235 
               
               
                 A3 
                 Benzyl 
                 C—CN 
                 CH 
                 2.06 
                 — 
                 568 
                  80 
               
               
                 A4 
                 2-methyl-4-cyano-phenyl 
                 CH 
                 CH 
                 2.07 
                 — 
                 568 
                   
               
               
                 A5 
                 Cyclopropyl 
                 CH 
                 CH 
                 — 
                 — 
                 — 
                 235 
               
               
                 A6 
                 Benzyl 
                 CH 
                 CH 
                 2.08 
                 — 
                 543 
                 — 
               
               
                 A7 
                 2-fluoro-Phenyl 
                 CH 
                 CH 
                 1.94 
                 549.28 
                 — 
                 — 
               
               
                 A8 
                 2-methyl-Phenyl 
                 CH 
                 CH 
                 1.96 
                 545.46 
                   
                 — 
               
               
                 A9 
                 2-chloro-Phenyl 
                 CH 
                 CH 
                 1.94 
                 565.25 
                   
                   
               
               
                 A10 
                 4-cyano-Phenyl 
                 CH 
                 CH 
                 1.9  
                 555.64 
                   
                   
               
               
                 A11 
                 4-nitro-Phenyl 
                 CH 
                 CH 
                 1.94 
                 576.25 
                   
                   
               
               
                 A12 
                 4-methyl-Phenyl 
                 CH 
                 CH 
                 2   
                 545.31 
                   
                   
               
               
                 A13 
                 2-methyl-4-fluoro-Phenyl 
                 CH 
                 CH 
                 1.98 
                 563.31 
                   
                   
               
               
                 A14 
                 2-fluoro-5-chloro-Phenyl 
                 CH 
                 CH 
                 2.05 
                 583.25 
                   
                   
               
               
                 A15 
                 4-nitro-2-chloro-Phenyl 
                 CH 
                 CH 
                 1.96 
                 610.24 
                   
                   
               
               
                 A16 
                 furanyl 
                 CH 
                 CH 
                 1.83 
                 521.27 
                   
                   
               
               
                 A17 
                 4-trifluoromethoxy- 
                 CH 
                 CH 
                 2.09 
                 615.27 
                   
                   
               
               
                   
                 Phenyl 
                   
                   
                   
                   
                   
                   
               
               
                 A18 
                 3-trifluoromethyl-4- 
                 CH 
                 CH 
                 2.1  
                 617.28 
                   
                   
               
               
                   
                 fluoro-Phenyl 
                   
                   
                   
                   
                   
                   
               
               
                 A19 
                 4-trifluoromethyl-Phenyl 
                 CH 
                 CH 
                 2.07 
                 599.28 
                   
                   
               
               
                 A20 
                 2-trifluoromethoxy- 
                 CH 
                 CH 
                 2.01 
                 615.34 
                   
                   
               
               
                   
                 Phenyl 
                   
                   
                   
                   
                   
                   
               
               
                 A21 
                 2-methoxy-Phenyl 
                 CH 
                 CH 
                 2.01 
                 561.3  
                   
                   
               
               
                 A22 
                 Phenyl 
                 CH 
                 CH 
                 1.92 
                 530.82 
                   
                   
               
               
                 A23 
                 4-fluoro-Phenyl 
                 CH 
                 CH 
                 1.95 
                 549.29 
                   
                   
               
               
                 A24 
                 2-trifluoromethyl-Phenyl 
                 CH 
                 CH 
                 1.96 
                 599.28 
                   
                   
               
               
                 A25 
                 4-fluoro-2-chloro-Phenyl 
                 CH 
                 CH 
                 1.97 
                 583.24 
                   
                   
               
               
                 A26 
                 4-Methyl- 
                 CH 
                 CH 
                 1.86 
                 553.25 
                   
                   
               
               
                   
                 [1,2,3]thiadiazolyl 
                   
                   
                   
                   
                   
                   
               
               
                 A27 
                 2,3-difluoro-phenyl 
                 CH 
                 CH 
                 1.96 
                 567.29 
                   
                   
               
               
                 A28 
                 2,4-difluoro-phenyl 
                 CH 
                 CH 
                 1.97 
                 566.76 
                   
                   
               
               
                 A29 
                 2-fluoro-5- 
                 CH 
                 CH 
                 2.07 
                 616.7  
                   
                   
               
               
                   
                 trifluoromethyl-Phenyl 
                   
                   
                   
                   
                   
                   
               
               
                 A30 
                 2-fluoro-Phenyl 
                 C—CN 
                 CH 
                 1.97 
                 574.26 
                   
                   
               
               
                 A31 
                 2-methyl-Phenyl 
                 C—CN 
                 CH 
                 1.95 
                 570.29 
                   
                   
               
               
                 A32 
                 2-chloro-Phenyl 
                 C—CN 
                 CH 
                 1.94 
                 590.24 
                   
                   
               
               
                 A33 
                 4-cyano-Phenyl 
                 C—CN 
                 CH 
                 1.85 
                 581.51 
                   
                   
               
               
                 A34 
                 4-nitro-Phenyl 
                 C—CN 
                 CH 
                 1.9  
                 601.06 
                   
                   
               
               
                 A35 
                 4-methyl-Phenyl 
                 C—CN 
                 CH 
                 1.98 
                 570.28 
                   
                   
               
               
                 A36 
                 2-methyl-4-fluoro- 
                 C—CN 
                 CH 
                 1.96 
                 588.28 
                   
                   
               
               
                   
                 Phenyl 
                   
                   
                   
                   
                   
                   
               
               
                 A37 
                 2-fluoro-5-chloro-Phenyl 
                 C—CN 
                 CH 
                 2.07 
                 608.22 
                   
                   
               
               
                 A38 
                 4-nitro-2-chloro-Phenyl 
                 C—CN 
                 CH 
                 1.94 
                 635.16 
                   
                   
               
               
                 A39 
                 furanyl 
                 C—CN 
                 CH 
                 1.84 
                 545.62 
                   
                   
               
               
                 A40 
                 4-trifluoromethoxy- 
                 C—CN 
                 CH 
                 2.05 
                 640.24 
                   
                   
               
               
                   
                 Phenyl 
                   
                   
                   
                   
                   
                   
               
               
                 A41 
                 3-trifluoromethyl-4- 
                 C—CN 
                 CH 
                 2.04 
                 642.28 
                   
                   
               
               
                   
                 fluoro-Phenyl 
                   
                   
                   
                   
                   
                   
               
               
                 A42 
                 4-trifluoromethyl-Phenyl 
                 C—CN 
                 CH 
                 2.03 
                 624.26 
                   
                   
               
               
                 A43 
                 2-trifluoromethoxy- 
                 C—CN 
                 CH 
                 2.01 
                 640.24 
                   
                   
               
               
                   
                 Phenyl 
                   
                   
                   
                   
                   
                   
               
               
                 A44 
                 2-methoxy-Phenyl 
                 C—CN 
                 CH 
                 2.15 
                 585.79 
                   
                   
               
               
                 A45 
                 Phenyl 
                 C—CN 
                 CH 
                 1.9  
                 556.26 
                   
                   
               
               
                 A46 
                 4-fluoro-Phenyl 
                 C—CN 
                 CH 
                 1.92 
                 574.24 
                   
                   
               
               
                 A47 
                 2-trifluoromethyl-Phenyl 
                 C—CN 
                 CH 
                 1.94 
                 624.27 
                   
                   
               
               
                 A48 
                 4-fluoro-2-chloro-Phenyl 
                 C—CN 
                 CH 
                 1.96 
                 608.19 
                   
                   
               
               
                 A49 
                 4-Methyl- 
                 C—CN 
                 CH 
                 1.82 
                 578.24 
                   
                   
               
               
                   
                 [1,2,3]thiadiazole 
                   
                   
                   
                   
                   
                   
               
               
                 A50 
                 2,3-difluoro-phenyl 
                 C—CN 
                 CH 
                 1.97 
                 591.61 
                   
                   
               
               
                 A51 
                 2,4-difluoro-phenyl 
                 C—CN 
                 CH 
                 2   
                 591.6  
                   
                   
               
               
                 A52 
                 2-fluoro-5- 
                 C—CN 
                 CH 
                 2.08 
                 641.77 
                   
                   
               
               
                   
                 trifluoromethyl-Phenyl 
                   
                   
                   
                   
                   
                   
               
               
                 A53 
                 2-fluoro-Phenyl 
                 C—Cl 
                 CH 
                 2.16 
                 583.24 
                   
                   
               
               
                 A54 
                 2-methyl-Phenyl 
                 C—Cl 
                 CH 
                 2.1  
                 579.22 
                   
                   
               
               
                 A55 
                 2-chloro-Phenyl 
                 C—Cl 
                 CH 
                 2.09 
                 599.16 
                   
                   
               
               
                 A56 
                 4-cyano-Phenyl 
                 C—Cl 
                 CH 
                 1.96 
                 590.22 
                   
                   
               
               
                 A57 
                 4-nitro-Phenyl 
                 C—Cl 
                 CH 
                 2.01 
                 610.23 
                   
                   
               
               
                 A58 
                 4-methyl-Phenyl 
                 C—Cl 
                 CH 
                 2.14 
                 579.27 
                   
                   
               
               
                 A59 
                 2-methyl-4-fluoro- 
                 C—Cl 
                 CH 
                 2.1  
                 597.24 
                   
                   
               
               
                   
                 Phenyl 
                   
                   
                   
                   
                   
                   
               
               
                 A60 
                 2-fluoro-5-chloro-Phenyl 
                 C—Cl 
                 CH 
                 2.24 
                 617.2  
                   
                   
               
               
                 A61 
                 4-nitro-2-chloro-Phenyl 
                 C—Cl 
                 CH 
                 2.05 
                 644.19 
                   
                   
               
               
                 A62 
                 furanyl 
                 C—Cl 
                 CH 
                 2   
                 555.21 
                   
                   
               
               
                 A63 
                 4-trifluoromethoxy- 
                 C—Cl 
                 CH 
                 2.18 
                 649.24 
                   
                   
               
               
                   
                 Phenyl 
                   
                   
                   
                   
                   
                   
               
               
                 A64 
                 3-trifluoromethyl-4- 
                 C—Cl 
                 CH 
                 2.15 
                 651.21 
                   
                   
               
               
                   
                 fluoro-Phenyl 
                   
                   
                   
                   
                   
                   
               
               
                 A65 
                 4-trifluoromethyl-Phenyl 
                 C—Cl 
                 CH 
                 2.16 
                 633.22 
                   
                   
               
               
                 A66 
                 2-trifluoromethoxy- 
                 C—Cl 
                 CH 
                 2.17 
                 649.23 
                   
                   
               
               
                   
                 Phenyl 
                   
                   
                   
                   
                   
                   
               
               
                 A67 
                 2-methoxy-Phenyl 
                 C—Cl 
                 CH 
                 2.21 
                 595.26 
                   
                   
               
               
                 A68 
                 Phenyl 
                 C—Cl 
                 CH 
                 2.05 
                 565.25 
                   
                   
               
               
                 A69 
                 4-fluoro-Phenyl 
                 C—Cl 
                 CH 
                 2.05 
                 583.23 
                   
                   
               
               
                 A70 
                 2-trifluoromethyl-Phenyl 
                 C—Cl 
                 CH 
                 2.06 
                 633.21 
                   
                   
               
               
                 A71 
                 4-fluoro-2-chloro-Phenyl 
                 C—Cl 
                 CH 
                 2.11 
                 617.19 
                   
                   
               
               
                 A72 
                 4-Methyl- 
                 C—Cl 
                 CH 
                 1.93 
                 587.21 
                   
                   
               
               
                   
                 [1,2,3]thiadiazolyl 
                   
                   
                   
                   
                   
                   
               
               
                 A73 
                 2,3-difluoro-phenyl 
                 C—Cl 
                 CH 
                 2.14 
                 601.22 
                   
                   
               
               
                 A74 
                 2,4-difluoro-phenyl 
                 C—Cl 
                 CH 
                 2.18 
                 601.24 
                   
                   
               
               
                 A75 
                 2-fluoro-5- 
                 C—Cl 
                 CH 
                 2.23 
                 651.23 
                   
                   
               
               
                   
                 trifluoromethyl-Phenyl 
                   
                   
                   
                   
                   
                   
               
               
                 A76 
                 4-cyano-2-methyl-phenyl 
                 C—Cl 
                 CH 
                   
                   
                 195 
                   
               
               
                 A77 
                 2-chlorothiazole-5-yl 
                 C—CN 
                 CH 
                 1.91 
                 596.92 
                   
                   
               
               
                 A78 
                 2-ethylhexanyl 
                 C—CN 
                 CH 
                 2.12 
                 578.35 
                   
                   
               
               
                 A79 
                 2,2,3,3,4,4,4- 
                 C—CN 
                 CH 
                 2.03 
                 647.95 
                   
                   
               
               
                   
                 heptafluorobutanyl 
                   
                   
                   
                   
                   
                   
               
               
                 A80 
                 2,2,3,3-tetrafluoro-1- 
                 C—CN 
                 CH 
                 1.95 
                 620.29 
                   
                   
               
               
                   
                 methyl-cyclobutanyl 
                   
                   
                   
                   
                   
                   
               
               
                 A81 
                 3-chloro-2,2-dimethyl- 
                 C—CN 
                 CH 
                 1.93 
                 570.23 
                   
                   
               
               
                   
                 propanyl 
                   
                   
                   
                   
                   
                   
               
               
                 A82 
                 butanyl 
                 C—CN 
                 CH 
                 1.93 
                 536.33 
                   
                   
               
               
                 A83 
                 4-(chloromethyl)phenyl 
                 C—CN 
                 CH 
                 1.97 
                 604.25 
                   
                   
               
               
                 A84 
                 6-chloropyridin-3-yl 
                 C—CN 
                 CH 
                 1.85 
                 591.23 
                   
                   
               
               
                 A85 
                 fluoromethyl 
                 C—CN 
                 CH 
                 1.63 
                 512.24 
                   
                   
               
               
                 A86 
                 4-methylsulfanylphenyl 
                 C—CN 
                 CH 
                 1.99 
                 602.25 
                   
                   
               
               
                 A87 
                 trichloromethyl 
                 C—CN 
                 CH 
                 1.97 
                 595.68 
                   
                   
               
               
                 A88 
                 1-(4- 
                 C—CN 
                 CH 
                 2.27 
                 658.3  
                   
                   
               
               
                   
                 chlorophenyl)cyclopentyl 
                   
                   
                   
                   
                   
                   
               
               
                 A89 
                 (E)-2-isobutoxyethenyl 
                 C—CN 
                 CH 
                 2.03 
                 578.31 
                   
                   
               
               
                 A90 
                 2,1,3-benzoxadiazol-5-yl 
                 C—CN 
                 CH 
                 1.91 
                 598.23 
                   
                   
               
               
                 A91 
                 1-methylbenzotriazol-5- 
                 C—CN 
                 CH 
                 1.75 
                 611.27 
                   
                   
               
               
                   
                 yl 
                   
                   
                   
                   
                   
                   
               
               
                 A92 
                 2-phenylthiazol-4-yl 
                 C—CN 
                 CH 
                 2.26 
                 639.2  
                   
                   
               
               
                 A93 
                 but-3-en-1-yl 
                 C—CN 
                 CH 
                 1.87 
                 534.29 
                   
                   
               
               
                 A94 
                 6-(trifluoromethyl)- 
                 C—CN 
                 CH 
                 1.92 
                 625.24 
                   
                   
               
               
                   
                 naphthal-3-yl 
                   
                   
                   
                   
                   
                   
               
               
                 A95 
                 1-phenylethyl 
                 C—CN 
                 CH 
                 2   
                 584.3  
                   
                   
               
               
                 A96 
                 2- 
                 C—CN 
                 CH 
                 2.12 
                 630.31 
                   
                   
               
               
                   
                 isopropylsulfanylphenyl 
                   
                   
                   
                   
                   
                   
               
               
                 A97 
                 (2,6-dichlorophenyl)- 
                 C—CN 
                 CH 
                 2.04 
                 638.22 
                   
                   
               
               
                   
                 methyl 
                   
                   
                   
                   
                   
                   
               
               
                 A98 
                 1-(4-chlorophenyl)-2- 
                 C—CN 
                 CH 
                 2.2  
                 646.29 
                   
                   
               
               
                   
                 methyl-propan-1-yl 
                   
                   
                   
                   
                   
                   
               
               
                 A99 
                 2-chloro-4- 
                 C—CN 
                 CH 
                 1.81 
                 668.15 
                   
                   
               
               
                   
                 methylsulfonyl-phenyl 
                   
                   
                   
                   
                   
                   
               
               
                 A100 
                 2-methylsulfanylethyl 
                 C—CN 
                 CH 
                 1.83 
                 554.24 
                   
                   
               
               
                 A101 
                 2-methylethyl 
                 C—CN 
                 CH 
                 1.84 
                 522.3  
                   
                   
               
               
                 A102 
                 4-tertButylPhenyl 
                 C—CN 
                 CH 
                 2.18 
                 612.3  
                   
                   
               
               
                 A103 
                 quinoxalin-2-yl 
                 C—CN 
                 CH 
                 2.1  
                 608.25 
                   
                   
               
               
                 A104 
                 5-methylisoxazol-3-yl 
                 C—CN 
                 CH 
                 1.92 
                 561.25 
                   
                   
               
               
                 A105 
                 tert-Butyl 
                 C—CN 
                 CH 
                 1.94 
                 536.28 
                   
                   
               
               
                 A106 
                 2-trifluoromethyl-4- 
                 C—CN 
                 CH 
                 1.98 
                 642.29 
                   
                   
               
               
                   
                 fluorophenyl 
                   
                   
                   
                   
                   
                   
               
               
                 A107 
                 phenylethyl 
                 C—CN 
                 CH 
                 1.98 
                 584.3  
                   
                   
               
               
                 A108 
                 2,4,6-trimethylphenyl 
                 C—CN 
                 CH 
                 2.05 
                 598.34 
                   
                   
               
               
                 A109 
                 2,4-dichlorophenyl 
                 C—CN 
                 CH 
                 2.04 
                 624.17 
                   
                   
               
               
                 A110 
                 cyclohexyl 
                 C—CN 
                 CH 
                 2.02 
                 562.31 
                   
                   
               
               
                 A111 
                 cyclobutyl 
                 C—CN 
                 CH 
                 1.89 
                 534.29 
                   
                   
               
               
                 A112 
                 3,5-difluoroPhenyl 
                 C—CN 
                 CH 
                 1.96 
                 592.28 
                   
                   
               
               
                 A113 
                 2,6-dichloroPhenyl 
                 C—CN 
                 CH 
                 1.96 
                 624.52 
                   
                   
               
               
                 A114 
                 naphthalene-1-yl 
                 C—CN 
                 CH 
                 2.01 
                 606.3  
                   
                   
               
               
                 A115 
                 4-fluorobenzyl 
                 C—CN 
                 CH 
                 1.93 
                 588.27 
                   
                   
               
               
                 A116 
                 3-trifluoromethylbenzyl 
                 C—CN 
                 CH 
                 2.03 
                 638.24 
                   
                   
               
               
                 A117 
                 3-chloro-4- 
                 C—CN 
                 CH 
                 1.98 
                 702.17 
                   
                   
               
               
                   
                 isopropylsulfonyl- 
                   
                   
                   
                   
                   
                   
               
               
                   
                 thiophen-2-yl 
                   
                   
                   
                   
                   
                   
               
               
                 A118 
                 3-chlorothiophen-2-yl 
                 C—CN 
                 CH 
                 2.07 
                 596.18 
                   
                   
               
               
                 A119 
                 2,5-dimethylpyrazol-3-yl 
                 C—CN 
                 CH 
                 1.82 
                 574.3  
                   
                   
               
               
                 A120 
                 2-thienylmethyl 
                 C—CN 
                 CH 
                 1.9  
                 576.19 
                   
                   
               
               
                 A121 
                 methyl propanoate-3-yl 
                 C—CN 
                 CH 
                 1.75 
                 566.28 
                   
                   
               
               
                 A122 
                 methoxymethyl 
                 C—CN 
                 CH 
                 1.8  
                 524.28 
                   
                   
               
               
                 A123 
                 (4-methoxyphenyl)- 
                 C—CN 
                 CH 
                 1.92 
                 600.3  
                   
                   
               
               
                   
                 methyl 
                   
                   
                   
                   
                   
                   
               
               
                 A124 
                 thiophen-2-yl 
                 C—CN 
                 CH 
                 1.87 
                 562.22 
                   
                   
               
               
                 A125 
                 ethenyl 
                 C—CN 
                 CH 
                 1.76 
                 506.25 
                   
                   
               
               
                 A126 
                 4-cyano-2-methyl-phenyl 
                 CH 
                 C—F 
                 2.06 
                 588   
                 586 
                 95-98 
               
               
                 A127 
                 cyclopropyl 
                 CH 
                 C—F 
                 2.00 
                 513   
                 511 
                 226-228 
               
               
                 A128 
                 4-pyridyl 
                 CH 
                 C—F 
                 1.92 
                 550   
                 548 
                 182-184 
               
               
                 A129 
                 2-methyl-4-nitro-phenyl 
                 CH 
                 C—F 
                 2.07 
                 608   
                 606 
                 178-180 
               
               
                 A130 
                 2,4,6-trifluoro-phenyl 
                 CH 
                 C—F 
                 2.08 
                 603   
                 601 
                 205-207 
               
               
                 A131 
                 2-chloro-4-cyano-phenyl 
                 CH 
                 C—F 
                 2.07 
                 608   
                 606 
                 201-203 
               
               
                 A132 
                 4-pyridyl-N-oxide 
                 CH 
                 C—F 
                 1.77 
                 566   
                 564 
                 227-229 
               
               
                 A133 
                 phenyl 
                 CH 
                 C—F 
                 2.01 
                 549   
                   
                 187-189 
               
               
                 A134 
                 4-fluoro-phenyl 
                 CH 
                 C—F 
                 2.02 
                 567   
                   
                 182-184 
               
               
                 A135 
                 5-chloro-3-pyridyl 
                 CH 
                 C—F 
                 1.99 
                 584   
                 582 
                 174-176 
               
               
                 A136 
                 3-pyridyl 
                 CH 
                 C—F 
                 1.87 
                 550   
                 548 
                 227-229 
               
               
                 A137 
                 4-pyridyl 
                 CH 
                 C—OMe 
                 1.91 
                 562   
                 560 
                 192-193 
               
               
                 A138 
                 3-pyridyl 
                 CH 
                 C—OMe 
                 1.91 
                 562   
                 560 
                 176-178 
               
               
                 A139 
                 phenyl 
                 CH 
                 C—OMe 
                 2.07 
                 561   
                   
                 220-223 
               
               
                 A140 
                 4-cyano-2-methyl-phenyl 
                 CH 
                 C—OMe 
                 1.14 
                 600   
                 598 
                 208-209 
               
               
                 A141 
                 cyclopropyl 
                 CH 
                 C—OMe 
                 1.99 
                 525   
                 523 
                 205-206 
               
               
                 A142 
                 3-pyridyl-N-oxide 
                 CH 
                 C—OMe 
                 1.78 
                 578   
                 576 
                 215-217 
               
               
                 A143 
                 4-pyridyl-N-oxide 
                 CH 
                 C—OMe 
                 0.96 
                 578   
                 576 
                 230-232 
               
               
                 A144 
                 2,4,6-trifluoro-phenyl 
                 CH 
                 C—OMe 
                 2.08 
                 615   
                   
                 201-202 
               
               
                 A145 
                 2-chloro-4-cyano-phenyl 
                 CH 
                 C—OMe 
                 2.06 
                 620   
                 618 
                 204-206 
               
               
                 A146 
                 6-chloro-3-pyridyl 
                 CH 
                 C—F 
                 1.91 
                 584   
                   
                   
               
               
                 A147 
                 2-pyridyl 
                 CH 
                 C—F 
                 2.07 
                 550   
                   
                   
               
               
                 A148 
                 3-(2-chloro-phenyl)-5- 
                 CH 
                 C—F 
                 2.12 
                 664   
                   
                   
               
               
                   
                 methyl-isoxazole-4-yl 
                   
                   
                   
                   
                   
                   
               
               
                 A149 
                 1-methyl-1H- 
                 CH 
                 C—F 
                 1.80 
                 604   
                   
                   
               
               
                   
                 benzotriazole-5-yl 
                   
                   
                   
                   
                   
                   
               
               
                 A150 
                 2-phenyl-thiazole-4-yl 
                 CH 
                 C—F 
                 2.28 
                 632   
                   
                   
               
               
                 A151 
                 6-trifluoromethyl-3- 
                 CH 
                 C—F 
                 1.98 
                 618   
                   
                   
               
               
                   
                 pyridyl 
                   
                   
                   
                   
                   
                   
               
               
                 A152 
                 1-phenyl-5- 
                 CH 
                 C—F 
                 2.08 
                 683   
                   
                   
               
               
                   
                 trifluoromethyl-1H- 
                   
                   
                   
                   
                   
                   
               
               
                   
                 pyrazole-4-yl 
                   
                   
                   
                   
                   
                   
               
               
                 A153 
                 5-chloro-l-methyl-1H- 
                 CH 
                 C—F 
                 1.86 
                 586   
                   
                   
               
               
                   
                 pyrazole-4-yl 
                   
                   
                   
                   
                   
                   
               
               
                 A154 
                 1-(4-chlorophenyl)-5- 
                 CH 
                 C—F 
                 2.16 
                 717   
                   
                   
               
               
                   
                 trifluoromethyl-1H- 
                   
                   
                   
                   
                   
                   
               
               
                   
                 pyrazole-4-yl 
                   
                   
                   
                   
                   
                   
               
               
                 A155 
                 1-(4-fluorophenyl)-5- 
                 CH 
                 C—F 
                 2.01 
                 647   
                   
                   
               
               
                   
                 methyl-1H-pyrazole-4-yl 
                   
                   
                   
                   
                   
                   
               
               
                 A156 
                 2,4-dimethyl-1,1,3- 
                 CH 
                 C—F 
                 1.94 
                 682   
                   
                   
               
               
                   
                 trioxo-2,3-dihydro-1H- 
                   
                   
                   
                   
                   
                   
               
               
                   
                 1lambda*6*- 
                   
                   
                   
                   
                   
                   
               
               
                   
                 benzo[d]isothiazole-5-yl 
                   
                   
                   
                   
                   
                   
               
               
                 A157 
                 2-chloro-3-pyridyl 
                 CH 
                 C—F 
                 1.85 
                 584   
                   
                   
               
               
                 A158 
                 5-methyl-2- 
                 CH 
                 C—F 
                 2.06 
                 621   
                   
                   
               
               
                   
                 trifluoromethyl-furan-3- 
                   
                   
                   
                   
                   
                   
               
               
                   
                 yl 
                   
                   
                   
                   
                   
                   
               
               
                 A159 
                 2-chloro-6-methoxy-4- 
                 CH 
                 C—F 
                 2.08 
                 614   
                   
                   
               
               
                   
                 pyridyl 
                   
                   
                   
                   
                   
                   
               
               
                 A160 
                 5-methyl-isoxazole-3-yl 
                 CH 
                 C—F 
                 1.96 
                 554   
                   
                   
               
               
                 A161 
                 1-phenyl-5-propyl-1H- 
                 CH 
                 C—F 
                 2.14 
                 657   
                   
                   
               
               
                   
                 pyrazole-4-yl 
                   
                   
                   
                   
                   
                   
               
               
                 A162 
                 5-methyl-3-(2-chloro-5- 
                 CH 
                 C—F 
                 2.12 
                 682   
                   
                   
               
               
                   
                 fluoro-phenyl)-isoxazole- 
                   
                   
                   
                   
                   
                   
               
               
                   
                 4-yl 
                   
                   
                   
                   
                   
                   
               
               
                 A163 
                 benzo[b]thiophene-2-yl 
                 CH 
                 C—F 
                 2.10 
                 605   
                   
                   
               
               
                 A164 
                 3-chloro- 
                 CH 
                 C—F 
                 2.32 
                 639   
                   
                   
               
               
                   
                 benzo[b]thiophene-2-yl 
                   
                   
                   
                   
                   
                   
               
               
                 A165 
                 benzo[c]thiophene-1-yl 
                 CH 
                 C—F 
                 2.10 
                 605   
                   
                   
               
               
                 A166 
                 5-methyl-2-phenyl-2H- 
                 CH 
                 C—F 
                 2.31 
                 630   
                   
                   
               
               
                   
                 [1,2,3]triazole-4-yl 
                   
                   
                   
                   
                   
                   
               
               
                 A167 
                 1-methyl-3-tert.butyl- 
                 CH 
                 C—F 
                 2.13 
                 609   
                   
                   
               
               
                   
                 1H-pyrazole-5-yl 
                   
                   
                   
                   
                   
                   
               
               
                 A168 
                 2,6-dichloro-4-pyridyl 
                 CH 
                 C—F 
                 2.08 
                 618   
                   
                   
               
               
                 A169 
                 3,5-dimethyl-isoxazole-4- 
                 CH 
                 C—F 
                 1.89 
                 568   
                   
                   
               
               
                   
                 yl 
                   
                   
                   
                   
                   
                   
               
               
                 A170 
                 5-methyl-3-phenyl- 
                 CH 
                 C—F 
                 2.07 
                 630   
                   
                   
               
               
                   
                 isoxazole-4-yl 
                   
                   
                   
                   
                   
                   
               
               
                 A171 
                 1-methyl-3-trifluormethyl- 
                 CH 
                 C—F 
                 2.18 
                 655   
                   
                   
               
               
                   
                 4-chloro-1H-pyrazole-5-yl 
                   
                   
                   
                   
                   
                   
               
               
                 A172 
                 3-chloro-4- 
                 CH 
                 C—F 
                 2.03 
                 695   
                   
                   
               
               
                   
                 (isopropylsulfonyl)- 
                   
                   
                   
                   
                   
                   
               
               
                   
                 thiophene-2-yl 
                   
                   
                   
                   
                   
                   
               
               
                 A173 
                 3-chloro-thiophene-2-yl 
                 CH 
                 C—F 
                 2.12 
                 589   
                   
                   
               
               
                 A174 
                 isoxazole-5-yl 
                 CH 
                 C—F 
                 1.81 
                 540   
                   
                   
               
               
                 A175 
                 2,5-dimethyl-furan-3-yl 
                 CH 
                 C—F 
                 2.04 
                 567   
                   
                   
               
               
                 A176 
                 1-tert-butyl-5-methyl- 
                 CH 
                 C—F 
                 2.21 
                 609   
                   
                   
               
               
                   
                 1H-imidazole-4-yl 
                   
                   
                   
                   
                   
                   
               
               
                 A177 
                 3-chloro-5- 
                 CH 
                 C—F 
                 2.17 
                 652   
                   
                   
               
               
                   
                 trifluoromethyl-2-pyridyl 
                   
                   
                   
                   
                   
                   
               
               
                 A178 
                 thiophene-2-yl 
                 CH 
                 C—F 
                 1.92 
                 555   
                   
                   
               
               
                 A179 
                 quinoline-2-yl 
                 CH 
                 C—F 
                 2.26 
                 600   
                   
                   
               
               
                 A180 
                 2-fluoro-phenyl 
                 CH 
                 C—F 
                 2.03 
                 567   
                   
                   
               
               
                 A181 
                 2-methyl-phenyl 
                 CH 
                 C—F 
                 2.00 
                 563   
                   
                   
               
               
                 A182 
                 2-chloro-phenyl 
                 CH 
                 C—F 
                 1.99 
                 583   
                   
                   
               
               
                 A183 
                 4-cyano-phenyl 
                 CH 
                 C—F 
                 1.90 
                 574   
                   
                   
               
               
                 A184 
                 4-nitro-phenyl 
                 CH 
                 C—F 
                 1.95 
                 594   
                   
                   
               
               
                 A185 
                 4-methyl-phenyl 
                 CH 
                 C—F 
                 2.02 
                 563   
                   
                   
               
               
                 A186 
                 2-methyl-4-fluoro-phenyl 
                 CH 
                 C—F 
                 2.01 
                 581   
                   
                   
               
               
                 A187 
                 2-fluoro-5-chloro-phenyl 
                 CH 
                 C—F 
                 2.13 
                 601   
                   
                   
               
               
                 A188 
                 4-nitro-2-chloro-phenyl 
                 CH 
                 C—F 
                 2.00 
                 628   
                   
                   
               
               
                 A189 
                 furanyl 
                 CH 
                 C—F 
                 1.87 
                 539   
                   
                   
               
               
                 A190 
                 4-trifluoromethoxy- 
                 CH 
                 C—F 
                 2.11 
                 633   
                   
                   
               
               
                   
                 phenyl 
                   
                   
                   
                   
                   
                   
               
               
                 A191 
                 3-trifluoromethyl-4- 
                 CH 
                 C—F 
                 2.10 
                 635   
                   
                   
               
               
                   
                 fluoro-phenyl 
                   
                   
                   
                   
                   
                   
               
               
                 A192 
                 4-trifluoromethyl-phenyl 
                 CH 
                 C—F 
                 2.09 
                 617   
                   
                   
               
               
                 A193 
                 2-trifluoromethoxy- 
                 CH 
                 C—F 
                 2.08 
                 633   
                   
                   
               
               
                   
                 phenyl 
                   
                   
                   
                   
                   
                   
               
               
                 A194 
                 2-methoxy-phenyl 
                 CH 
                 C—F 
                 2.12 
                 579   
                   
                   
               
               
                 A195 
                 2-trifluoromethyl-phenyl 
                 CH 
                 C—F 
                 2.00 
                 617   
                   
                   
               
               
                 A196 
                 4-fluoro-2-chloro-phenyl 
                 CH 
                 C—F 
                 2.02 
                 601   
                   
                   
               
               
                 A197 
                 4-Methyl- 
                 CH 
                 C—F 
                 1.88 
                 571   
                   
                   
               
               
                   
                 [1,2,3]thiadiazolyl 
                   
                   
                   
                   
                   
                   
               
               
                 A198 
                 2,3-difluoro-phenyl 
                 CH 
                 C—F 
                 2.03 
                 585   
                   
                   
               
               
                 A199 
                 2,4-difluoro-phenyl 
                 CH 
                 C—F 
                 2.05 
                 585   
                   
                   
               
               
                 A200 
                 2-fluoro-4- 
                 CH 
                 C—F 
                 2.14 
                 635   
                   
                   
               
               
                   
                 trifluoromethyl-phenyl 
                   
                   
                   
                   
                   
                   
               
               
                 A201 
                 2-methyl-4-nitro-phenyl 
                 CH 
                 C—OMe 
                 2.08 
                 620   
                 618 
                 215-217 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE B 
               
             
            
               
                   
               
               
                 Compounds of formula (I′): R 2  = H, A 1  = CH 
               
            
           
           
               
               
            
               
                   
                 (I′) 
               
               
                 
                   
                     
                     
                         
                         
                     
                   
                 
                   
               
               
                   
               
            
           
           
               
               
               
               
               
               
               
               
            
               
                   
                   
                   
                   
                 RT 
                   
                 M − 
                 MP 
               
               
                 Ex. 
                 Q 1   
                 R 1   
                 A 4   
                 (min) 
                 MH +   
                 H +   
                 (° C.) 
               
               
                   
               
               
                 B1 
                 phenyl 
                 ethyl 
                 C—F 
                 2.05 
                 577 
                   
                 68-70 
               
               
                 B2 
                 4-fluoro-phenyl 
                 ethyl 
                 C—F 
                 2.07 
                 595 
                   
                 133-135 
               
               
                 B3 
                 3-pyridyl 
                 ethyl 
                 C—F 
                 1.93 
                 578 
                   
                 54-56 
               
               
                 B4 
                 4-pyridyl 
                 ethyl 
                 C—F 
                 1.91 
                 578 
                   
                 74-76 
               
               
                 B5 
                 4-pyridyl 
                 methyl 
                 C—OMe 
                 1.87 
                 576 
                   
                 83-85 
               
               
                 B6 
                 3-pyridyl 
                 methyl 
                 C—OMe 
                 1.89 
                 576 
                   
                 80-83 
               
               
                 B7 
                 4-nitro-phenyl 
                 methyl 
                 C—OMe 
                 2.03 
                 620 
                   
                 92-94 
               
               
                 B8 
                 phenyl 
                 methyl 
                 C—OMe 
                 2.03 
                 575 
                   
                 143-145 
               
               
                 B9 
                 4-pyridyl- 
                 methyl 
                 C—OMe 
                 1.78 
                 592 
                   
                 183-185 
               
               
                   
                 N-oxide 
                   
                   
                   
                   
                   
                   
               
               
                 B10 
                 3-pyridyl- 
                 methyl 
                 C—OMe 
                 1.79 
                 592 
                   
                 97-99 
               
               
                   
                 N-oxide 
                   
                   
                   
                   
                   
                   
               
               
                 B11 
                 2,4,6-trifluoro- 
                 methyl 
                 C—OMe 
                 2.07 
                 629 
                   
                 80-82 
               
               
                   
                 phenyl 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE C 
               
               
                   
               
             
            
               
                 Compound of formula (IIIb): R 2   = H 
               
            
           
           
               
               
            
               
                   
                 (IIIb) 
               
               
                 
                   
                     
                     
                         
                         
                     
                   
                 
                   
               
               
                   
               
            
           
           
               
               
               
               
               
               
            
               
                 Compound 
                   
                   
                 RT 
                   
                   
               
               
                 No. 
                 A 1   
                 A 4   
                 (min) 
                 M measured 
                 MP° C. 
               
               
                   
               
               
                 C1 
                 C—CN 
                 CH 
                 2.05 
                 526 (M − CH 3 CO 2   − ) 
                   
               
               
                 C2 
                 C—Cl 
                 CH 
                 2.05 
                 535 (M − HCO 2   − ) 
                   
               
               
                 C3 
                 CH 
                 C—OMe 
                 2.02 
                 487 (M + H) +   
                 128-130 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE D 
               
               
                   
               
             
            
               
                 Compound of formula (III′): R 2  = H 
               
            
           
           
               
               
            
               
                   
                 (III′) 
               
               
                 
                   
                     
                     
                         
                         
                     
                   
                 
                   
               
               
                   
               
            
           
           
               
               
               
               
               
               
               
            
               
                 Compound 
                   
                   
                   
                   
                   
                   
               
               
                 No. 
                 A 1   
                 A 4   
                 R 1   
                 RT (min) 
                 MH +   
                 MP° C. 
               
               
                   
               
               
                 D1 
                 CH 
                 CH 
                 H 
                 1.89 
                 427 
                   
               
               
                 D2 
                 C—CN 
                 CH 
                 H 
                 1.97 
                 452 
                   
               
               
                 D3 
                 C—Cl 
                 CH 
                 H 
                 2.00 
                 461 
                   
               
               
                 D4 
                 CH 
                 C—F 
                 H 
                 1.97 
                 445 
                 137-139 
               
               
                 D5 
                 CH 
                 C—OMe 
                 H 
                 1.96 
                 457 
                 152-154 
               
               
                 D6 
                 CH 
                 C—F 
                 ethyl 
                 2.07 
                 473 
                   
               
               
                 D7 
                 CH 
                 C—OMe 
                 methyl 
                 2.08 
                 485 
               
               
                   
               
            
           
         
       
     
     Biological Examples 
     This illustrates the pesticidal/insecticidal properties of compounds of formula (I). Tests were performed as follows: 
       Spodoptera littoralis  (Egyptian cotton leafworm): 
     Cotton leaf discs were placed on agar in a 24-well microtiter plate and sprayed with test solutions at an application rate of 200 ppm. After drying, the leaf discs were infested with 5 L1 larvae. The samples were checked for mortality, feeding behaviour, and growth regulation 3 days after treatment (DAT). 
     The following compounds gave at least 80% control of  Spodoptera littoralis : A1, A3, A4, A5, A6, A8, A9, A10, All, A13, A15, A16, A17, A22, A23, A25, A28, A30, A31, A32, A33 to A36, A38 to A40, A45 to A51, A76, A56, A59, A77, A80, A82, A84, A85, A86, A87, A90, A91, A93, A94, A99, A101, A104, A105, A106, A111, A112, A115, A120, A122, A124, A126, A128, A129, A131, A132, 133, A134, A135, A136, A137, A138, A143, A144, A145, B1, B2, B3, B4, B5, B6, B7, B8, B9, B10. 
       Heliothis virescens  (Tobacco budworm): 
     Eggs (0 to 24 h old) were placed in 24-well microtiter plate on artificial diet and treated with test solutions at an application rate of 200 ppm (concentration in well 18 pm) by pipetting. After an incubation period of 4 days, samples were checked for egg mortality, larval mortality, and growth regulation. 
     The following compounds gave at least 80% control of  Heliothis virescens : A1, A2, A3, A4, A5, A8, A9, A10, All, A13, A14, A15, A16, A17, A19, A20, A22, A23, A25, A30, A31, A32, A33, A34, A36, A37, A38, A39, A40, A41, A42, A45, A46, A47, A48, A49, A50, A51, A76, A56, A57, A59, A61, A65, A68, A69, A72, A82, A86, A90, A101, A112, A115, A126, A128, A129, A130, A131, A132, 133, A134, A135, A136, A137, A138, A139, A140, A142, A143, A144, A145, A146, A147, A149, A151, A157, A158, A159, A167, A168, A178, A180, A181, A182, A183, A184, A186, A187, A188, A189, A190, A192, A195, A196, A197, A198, A199, B1, B2, B3, B4, B5, B6, B7, B8, B9, B10. 
       Plutella xylostella  (Diamond back moth): 
     24-well microtiter plate (MTP) with artificial diet was treated with test solutions at an application rate of 200 ppm (concentration in well 18 ppm) by pipetting. After drying, the MTP&#39;s were infested with L2 larvae (7 to 12 per well). After an incubation period of 6 days, samples were checked for larval mortality, and growth regulation. 
     The following compounds gave at least 80% control of  Plutella xylostella : A1, A3, A4, A5, A6, A10, A12, A13, A15, A22, A23, A25, A28, A31, A32, A33, A34, A35, A36, A38, A39, A40, A41, A42, A45, A46, A48, A49, A50, A51, A76, A56, A57, A59, A61, A79, A80, A83, A84, A86, A87, A90, A91, A93, A94, A95, A104, A106, A111, A112, A123, A126, A128, A129, A130, A131, A132, 133, A134, A135, A136, A137, A138, A142, A143, A144, A145, A146, A151, A157, A159, A163, A168, A178, A181, A182, A183, A184, A188, A189, A192, A195, A197, A199, B1, B2, B3, B4, B5, B6, B7, B8, B9, B10. 
       Diabrotica balteata  (Corn root worm): 
     A 24-well microtiter plate (MTP) with artificial diet was treated with test solutions at an application rate of 200 ppm (concentration in well 18 ppm) by pipetting. After drying, the MTP&#39;s were infested with L2 larvae (6 to 10 per well). After an incubation period of 5 days, samples were checked for larval mortality and growth regulation. 
     The following compound gave at least 80% control of  Diabrotica balteata : A1, A2, A3, A4, A5, A6, A10, All, A12, A23, A30, A32, A33, A34, A35, A38, A39, A40, A42, A45, A46, A48, A49, A51, A76, A56, A57, A59, A61, A65, A68, A69, A80, A81, A82, A84, A87, A93, A101, A106, A109, A112, A115, A124, A126, A128, A129, A131, A132, 133, A134, A135, A136, A137, A138, A143, A144, A145, A146, A151, A157, A158, A159, A168, A175, A178, A180, A181, A182, A183, A184, A188, A189, A190, A191, A192, A195, A197, A198, A199, B1, B2, B3, B4, B5, B6, B7, B8, B9. 
       Tetranychus urticae  (Two-spotted spider mite): 
     Bean leaf discs on agar in 24-well microtiter plates were sprayed with test solutions at an application rate of 200 ppm. After drying, the leaf discs were infested with mite populations of mixed ages. 8 Days later, discs were checked for egg mortality, larval mortality, and adult mortality. 
     The following compounds gave at least 80% control of  Tetranychus urticae : A1, A3, A4, A5, A6, A31, A45, A46, A48, A49, A76, A80, A81, A82, A86, A90, A100, A101, A109, A110, A115, A124, A126, A128, A129, A132, A136, A143, A144, A145, B3, B4, B5, B6, B7, B9, B10. 
       Thrips tabaci  (Onion thrips): 
     Sunflower leaf discs were placed on agar in a 24-well microtiter plate and sprayed with test solutions at an application rate of 200 ppm. After drying, the leaf discs were infested with an aphid population of mixed ages. After an incubation period of 7 days, samples were checked for mortality. 
     The following compounds gave at least 80% control of  Thrips tabaci : A4, A5, A10, All, A23, A25, A33, A34, A36, A40, A42, A45, A46, A48, A49, A50, A56, A80, A82, A84, A86, A94, A100, A101, A111, A112, A124, A126, A128, A132, A134, A137, A143, A168, B1, B2, B3, B4, B5, B6, B9. 
       Myzus persicae  (Green peach aphid): 
     Sunflower leaf discs are placed on agar in a 24-well microtiter plate and sprayed with test solutions at an application rate of 200 ppm. After drying, the leaf discs are infested with an aphid population of mixed ages. After an incubation period of 6 DAT, samples are checked for mortality. 
     The following compounds gave at least 80% control of  Myzus persicae : A46, A128, A132, A135, A137, B1, B2, B3, B4, B5, B9, B10.