Patent Publication Number: US-11642298-B2

Title: Peptide composition and respective uses

Description:
CROSS-REFERENCE TO RELATED APPLICATIONS 
     This application is a Continuation Application of U.S. patent application Ser. No. 15/030,313, filed Apr. 18, 2016, which is a U.S. National Stage Application under 35 U.S.C. § 371 of International Patent Application No. PCT/IB2014/065375, filed Oct. 16, 2014 which claims priority to Portugal Application No. 107244, filed Oct. 18, 2013, which are hereby incorporated by reference in their respective entireties. 
    
    
     INCORPORATION-BY-REFERENCE OF SEQUENCE LISTING 
     A sequence listing, filed as the ASCII text file “P159.6 seq. listing” having a file size of 185 kilobytes, is incorporated herein by reference in its entirety. 
     TECHNICAL DOMAIN 
     The current application corresponds to a composition that comprises at least one peptide, based on keratin and keratin associated proteins, containing 2 to 5 cysteines with the purpose of treatment and cosmetics of animal hair, in preference human hair. 
     PRIOR ART 
     Human hair has a significant social role in most of the various world cultures, particularly for female population. Thus, there is a constant desire to improve and change hair characteristics, such as its natural texture. 
     There are several differences in hair characteristics between different human ethnicities, as well as between individuals of the same ethnicity, such as length, thickness, color and texture. 
     Hair is composed of approximately 65% to 95% protein. The remaining constituents include water, lipids, pigments and trace elements. The majority of the proteins present in human hair correspond to keratin and keratin-associated proteins. 
     Human hair fibers structure consists of cuticle, cortex and medulla. The cuticle constitutes about 15% by weight of the hair and consists of overlapping layers of cells, similar to a system of scales, with high content of cysteine. It provides a protective character to the hair fiber. The cortex is the middle region of the hair being responsible for the strength, elasticity and hair color. It is composed of several cell types and represents about 80% of the weight of the hair. The medulla corresponds to a central beam of cells, and is absent in some hairs. 
     Keratins and mainly keratin-associated proteins have high sulfur content, present in the cysteine amino acid. The presence of sulfur is essential to the hair structure, as it allows the formation of disulfide bonds between amino acids of the polypeptide chains, due to oxidation of cysteine. The existence of these bonds is largely responsible for the structure and texture of the hair. 
     There are several hair styling methods that involve breakage and reestablishment of disulfide bonds, allowing relaxation and straightening of the hair. However, the most effective methods currently used to modulate hair contain harmful chemicals such as sodium hydroxide, potassium hydroxide, lithium hydroxide, guanidine hydroxide, ammonium thioglycolate or sodium sulfate. These methods can damage the scalp and the hair fiber, leading to its weakening and reducing its tensile strength. Formaldehyde, an extremely toxic chemical, is also used in hair straightening products. Other hair treatments that do not involve so much damage to the hair and the consumer are usually very expensive, time-consuming and/or have low efficacy. Thus there is a constant demand for formulations that efficiently model the hair fiber without damage. 
     Peptides, proteins, amino acids and its derivatives have also been used in compositions for personal care products, namely hair conditioning and strengthening. For example, the document WO 00/23039 discloses a composition for hair treatment containing intermediate filament proteins, namely artificial keratin. The document EP 0488242 discloses a hair treating agent containing 3% to 10% by weight of cysteine and salts thereof, a polyhydric alcohol or a saccharide containing four to twenty carbon atoms, three or more hydroxyl groups in the molecule and no aldehyde or ketone group. 
     The current invention is distinguished by the use of peptides, while the other applications refer the use of, respectively, proteins and amino acids in isolation and together with other types of compounds. The peptides in this innovation peptide can penetrate into the human hair in order to improve hair fiber resistance. 
     The document WO 00/51556 discloses a hair treatment composition that contains four or more discrete amino acids selected from histidine, lysine, methionine, tyrosine, tryptophan or cysteine. This document describes peptides without referring sequences and providing a composition essentially based on histidine, lysine, methionine, tyrosine, tryptophan or cysteine. 
     The document PT 103484 describes a formulation for cosmetic applications that uses hydrophobic binding domains and/or carbohydrates, in order to enhance its properties and to repair hair damage. The binding domains used are hydrolyzed milk protein, a model of human surfactant protein as well as biologically active and synthetic peptides. The current invention is distinguished by the innovative use of synthetic peptide sequences analogous to keratin proteins instead of surfactant proteins. Furthermore, it does not rely on hydrophobic binding domains and/or carbohydrates, but in other interactions, namely disulfide bonds. 
     Enzymes have also been used as activating agents for hair treatment, such as in the document WO 00/64405. The document WO 2012/13593 discloses a cosmetic kit for hair conformational change that acts specifically in the disulfide bonds of the hair keratin, through enzyme activating agents and proteolytic enzymes. 
     As described in the last document there are hair treatments that include actions at the level of the hair disulfide bonds. Below we highlight some examples. 
     The document WO 97/11672 reports a method for permanent hair processing using tris(2-carboxyethyl)phosphine (TCEP), and other water-soluble tertiary phosphines to break disulfide bonds, whose reaction occurs in acidicic environment. The document U.S. Pat. No. 5,635,170 discloses a composition for permanent shaping of hair based on a keratin reducing agent, which contains N-glycyl-L-cysteine and/or L-cysteinyl-glycine. The pH range of this composition is 6.5 to 9.0. The document WO 2008/081348 refers a method and composition for permanent modulation of hair, through the use of 1% to 30% of N-alkyl-2-mercapto acetamide as a keratin reducing agent. It also contains at least one cationic surfactant for permanently shaping hair and the resulting process. The document WO 2006/001536 describes an agent for permanent hair processing that contains a derivative of mercaptocarboxylic acid, which allows processing and reduction of hair keratin in the acidic and neutral range of the pH. The document US 2010/0272666 discloses a hair cosmetic composition for hair treatment, containing 5 to 50 amino acids, without containing cysteine or its derivatives. Thus, this invention is distinguished by the existence of specific amino acid sequences, which contain cysteine, allowing the formation of disulfide bonds that stabilize and protect the hair fiber. 
     In a previous article by Fernandes et al. (Fernandes, Lima, Loureiro, Gomes, &amp; Cavaco-Paulo, 2012), it is performed the toxicology evaluation of a peptide sequence for hair care use, containing 13 amino acids with two cysteines in its composition. However, in this article it is not mentioned or suggested that the percentage of cysteine in a peptide sequence may have some effect on the resistance of the hair. Also, in the present innovation, the number of amino acids of each peptide sequence is 6 to 12. 
     General Description 
     Thus, the present invention aims to provide a composition for treatment of the hair, including animal and human hair, without the use of chemicals harmful to the hair fiber and consumer health and that does not present the drawbacks found in the state of the art. 
     The compositions described in the current invention, after prolonged use, provide hair with soft, shiny, undamaged texture and with the desired features. The peptide compositions with a specific number of amino acids and cysteines act synergically providing resistance to strength, toughness and elasticity to the hair. Therefore, the compositions of the current invention are particularly relevant for hair treatment, hair dying, hair perms, etc. 
     The present application describes a peptide composition for hair treatment, in particular human or animal hair, which comprises at least one peptide with 6-12 amino acids length (namely 6, 7, 8, 9, 10, 11, 12 amino acids), where 2-5 of those amino acids correspond to cysteine, preferably 2, 3, 4 or 5 of those amino acids are cysteines and dermatologically suitable excipients, which penetrates the hair, increasing it resistance and reducing it breakage. 
     In the embodiment, for improved results, the peptide (or peptides) of the peptide composition for hair care can comprise 10-11 amino acids. 
     In the embodiment of the peptide composition for hair care treatment, the referred peptides can also contain a percentage of hydrophobic amino acids, not higher than 60%, and preferably less than 41% for better results. Preferably, the composition can also comprise at least one hydrophobic amino acid selected from the following list: phenylalanine, alanine, leucine, methionine, isoleucine, tryptophan, proline, valine or their mixtures. 
     In yet another embodiment, the amount of cysteine of the peptide composition for hair treatment may vary from 10% to 50% of the total of amino acids of the peptide sequence, preferably 20-30%, and even more preferably 25%. 
     In an embodiment of the composition, with better results of the peptide (or peptides) of the peptide composition for hair treatment, the sequence of peptide(s) can comprise at least one sequence of the following list with a with a degree of homology greater than or equal to 90%: SEQ.ID NO:1-SEQ.ID NO:1239, preferably with a degree of homology greater than or equal to 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, 100%. 
     In an embodiment, improved results for the peptide (or peptides) of the peptide composition for hair treatment can comprise at least one of the sequences of the following list with a degree of homology equal or greater than 90%: SEQ.ID NO:5, SEQ.ID NO:75; SEQ.ID NO:94; SEQ.ID NO: 409; SEQ.ID NO:411; SEQ.ID NO:412; SEQ ID. NO:432; SEQ.ID NO:618; SEQ.ID NO:717; SEQ.ID NO:951; SEQ.ID NO:1088; SEQ.ID NO:1131; SEQ.ID NO:1149, preferably with a degree of homology equal or greater than 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, 100%. 
     In other embodiment, the concentration of the peptide of the peptide composition for hair treatment can vary between 0.001%-20% (w/w), preferably 0.01-5% (w/w). 
     In yet other embodiment, the peptide composition for hair treatment can comprise at least one excipient, selected from the following list: surfactants, emulsifiers, preservatives, thickeners, organic polymers, humectants, silicones, oils, fragrances, vitamins, buffers. 
     In another embodiment, the peptide composition for hair treatment can comprise at least one anionic surfactant selected from the following list: alkylbenzene sulfonates, ammonium lauryl sulfate, ammonium lauryl sulfate, ammonium xylenesulfonate, sodium C14-16 olefin sulfonate, sodium cocoyl sarcosinate, sodium laureth sulfate, sodium lauryl sulfate, sodium lauryl sulfoacetate, sodium myreth sulfate, sodium xylenesulfonate, TEA-dodecylbenzenesulfonate, ethyl PEG-15 cocamine sulfate, dioctyl sodium sulfosuccinate, or any mixture thereof. 
     In an embodiment, the peptide composition for hair treatment can comprise at least one amphoteric surfactant selected from the following list: cocamidopropyl betaine, coco betaine, cocoamphoacetate, cocoamphodipropionate, disodium cocoamphodiacetate, disodium cocoamphodipropionate, lauroamphoacetate, sodium cocoyl isethionate, or any mixture thereof. 
     In other embodiment, the peptide composition for hair treatment can comprise at least one cationic surfactant selected from the following list: quaternary ammonium compounds, behentrimonium chloride, behentrimonium methosulfate, benzalkonium chloride, betrimonium chloride, binnamidopropyltrimonium chloride, cocotrimonium chloride, dicetyldimonium chloride, dicocodimonium chloride, dihydrogenated tallow dimethylammonium chloride, hydrogenated Palm trimethylammonium chloride, laurtrimonium chloride, quaternium-15, quaternium-18 bentonite, quaternium-22 hectonite, stearalkonium chloride, tallowtrimonium chloride, tricetyldimonium chloride, or any mixture thereof. 
     In yet other embodiment, the peptide composition for hair treatment can comprise at least one non-ionic surfactant selected from the following list: decyl glucoside, laureth-10 (lauryl ether 10), laureth-23, Laureth-4, PEG-10 sorbitan laurate, polysorbate-(20, 21, 40, 60, 61, 65, 80, 81), PPG-1 trideceth-6, sorbitol, steareth-(2, 10, 15, 20), C11-21 pareth-(3-30), C12-20 acid PEG-8 ester, or their mixtures. 
     In yet other embodiment, the peptide composition for hair treatment can comprise at least one emulsifier selected from the following list: caprylic/capric/diglyceryl succinate, C10-15 pareth-(2,4,6,8) phosphate, C14-16 glycol palmitate, C18-20 glycol isostearate, ceteareth-(4-60), cocamidopropyl lauryl ether, deceth-(3-10), DIPA-hydrogenated cocoate, dipentaerythrityl hydroxystearate, dipentaerythrityl hydroxyisostea rate, dipentaerythrityl hexacaprate/caprylate, dodoxynol-(5,6,7,9,12), nonoxynol-(1-35), octoxynol-(1-70), Octyldodeceth-(2,5,16,20,25), Palm kernel glycerides, or any mixture thereof. 
     In other embodiment, the peptide composition for hair treatment can comprise at least one preservative selected from the following list: butyl paraben, diazolidinyl urea, DMDM hydantoin, ethyl paraben, imidazolidinyl urea, iodopropynyl butylcarbamate, isobutyl paraben, methyl paraben, methylchloroisothiazolinone, methylisothiazolinone, phenoxyethanol, propyl paraben, sodium benzoate, or any mixture thereof. 
     In other embodiment, the peptide composition for hair treatment can comprise at least one thickner selected from the following list: aluminum stearates/isostearates/myristates/laurates/palmitates, glycol distearate, hydrogenated castor oil, hydrogenated castor oil hydroxystearate, hydrogenated castor oil isostearate, hydrogenated castor oil stearate, hydrogenated castor PEG-8 esters, PEG-150 distea rate, or any mixture thereof. 
     In other embodiment, the peptide composition for hair treatment can comprise at least one natural polymer derived selected from the following list: carboxymethyl hydroxyethyl celulose, carboxymethyl hydroxypropyl guar, cellulose, ethyl celulose, hydroxybutyl methylcellulose, hydroxyethylcellulose, hydroxymethylcellulose, lauryl polyglucose, or any mixture thereof. 
     In other embodiment, the peptide composition for hair treatment can comprise at least one humectant selected from the following list: 1,2,6 hexanetriol, dipropylene glycol, glycerin, hexylene glycol, panthenol, phytantriol, propylene glycol, sodium PCA, sorbitol, triethylene glycol, polyglyceryl sorbitol, glucose, fructose, polydextrose, potassium PCA, hydrogenated honey, hyaluronic acid, inositol, hexanediol beeswax, hexanetriol beeswax, hydrolyzed elastin, hydrolyzed collagen, hydrolyzed silk, hydrolyzed keratin, erythritol, capryl glycol, isoceteth-(3-10, 20, 30), isolaureth-(3-10, 20, 30), laneth-(5-50), laureth-(1-30), steareth-(4-20), trideceth-(5-50), or any mixture thereof. 
     In other embodiment, the peptide composition for hair treatment can comprise at least one cationic polymer selected from the following list: polyquaternium-10, polyquaternium-7, polyquaternium-11m guar hydroxypropyltrimonium chloride, or any mixture thereof. 
     In other embodiment, the peptide composition for hair treatment can comprise at least one silicone selected from the following list: amodimethicone, amodimethicone, trideceth-12, cetrimonium, chloride mixture, behenoxy, dimethicone sparingly, cetearyl methicone, cetyl dimethicone, cyclomethicone, cyclopentasiloxane, dimethicone, dimethicone copolyol, dimethicone copolyol, dimethiconol, hydrolyzed wheat protein hydroxypropyl polysiloxane, stearoxy dimethicone sparingly, stearyl dimethicone, trimethylsilylamodimethicone, lauryl methicone copolyol, or any mixture thereof. 
     In yet other embodiment, the peptide composition for hair treatment can comprise at least one organic oil selected from the following list: mineral oil, paraffin, petrolatum, or any mixture thereof. 
     In yet other embodiment, the peptide composition for hair treatment can comprise at least one protein selected from the following list: cocodimonium hydroxypropyl hydrolyzed casein, cocodimonium hydroxypropyl hydrolyzed collagen, cocodimonium hydroxypropyl hydrolyzed hair keratin, cocodimonium hydroxypropyl hydrolyzed keratin, cocodimonium hydroxypropyl hydrolyzed rice protein, cocodimonium hydroxypropyl hydrolyzed silk, cocodimonium hydroxypropyl hydrolyzed soy protein, cocodimonium hydroxypropyl hydrolyzed wheat protein, cocodimonium hydroxypropyl silk amino acids, cocoyl hydrolyzed collagen, cocoyl hydrolyzed keratin, hydrolyzed keratin, hydrolyzed oat flour, hydrolyzed silk, hydrolyzed silk protein, hydrolyzed soy protein, hydrolyzed wheat protein, hydrolyzed wheat protein, keratin, potassium cocoyl hydrolyzed collagen, TEA-cocoyl hydrolyzed collagen, TEA-cocoyl hydrolyzed soy protein, or any mixture thereof. 
     In other embodiment, the peptide composition for hair treatment can comprise at least one vitamin selected from the following list: retinol, retinyl palmitate tocopherol acetate, or any mixture thereof. 
     In other embodiment, the peptide composition for hair treatment can comprise at least one ester emollient selected from the following list: butyl myristate, butyl stearate, C12-15 alkyl benzoate, caprylic/capric triglyceride, cetyl octanoate, cetyl stearate, cetearyl stearate, decyl oleate, dimethyl lauramine isostearate, glyceryl stearate, glyceryl adipate, glyceryl arachidate, glyceryl arachidonate, glyceryl behenate, glyceryl caprate, glyceryl caprylate, glyceryl caprylate/caprate, glyceryl citrate/lactate/linoleate/oleate, glyceryl cocoate, glyceryl diarachidate, glyceryl dibehenate, glyceryl dierucate, glyceryl dihydroxystearate, glyceryl diisopalmitate, glyceryl diisostearate, glyceryl dilaurate, glyceryl dilinoleate, glyceryl dimyristate, glyceryl dioleate, glyceryl dipalmitate, glyceryl dipalmitoleate, glyceryl diricinoleate, glyceryl distearate, glyceryl erucate, glycol stearate, isocetyl stearate, isopropyl myristate, isopropyl palmitate, isopropyl stearate, isostearyl stearate, octyl palmitate, octyl stearate, propylene glycol dicaprylate/dicaprate, sorbitan benzoate, sorbitan caprylate, sorbitan isostearate, Sorbitan laurate, sorbitan tristearate, stearyl stearate, tocopheryl linoleate, or any mixture thereof. 
     In other embodiment, the peptide composition for hair treatment can comprise at least one alkanolamide selected from the following list: acetamide MEA, cocamide DEA, cocamide MEA, lactamide MEA, lauramide DEA, lauramide DEA, propylene glycol, lauramide MEA, lecithinamide DEA, linoleamide DEA, linoleamide MEA, linoleamide MIPA, myristamide DEA, myristamide MEA, myristamide MIPA, oleamide DEA, oleamide DEA, oleamide MEA, oleamide MIPA, soyamide DEA, stearamide MEA, or any mixture thereof. 
     In yet other embodiment, the peptide composition for hair treatment can comprise at least one amine selected from the following list: behentamidopropyl dimethylamine, cocamidopropyl dimethylamine, isostearamidopropyl dimethylamine, lauramidopropyl dimethylamine, myristamidopropyl dimethylamine, oleamidopropyl dimethylamine, palmitamidopropyl dimethylamine, stearamidopropyl dimethylamine, tallamidopropyl dimethylamine, or any mixture thereof. 
     In yet other embodiment, the peptide composition for hair treatment can comprise at least one pH adjuster selected from the following list: ascorbic acid, citric acid, sodium hydroxide, triethanolamine, or any mixture thereof. 
     In yet other embodiment, the peptide composition for hair treatment can comprise at least one salt selected from the following list: calcium chloride, magnesium chloride, magnesium sulfate, potassium chloride, potassium glycol sulfate, sodium chloride, or any mixture thereof. 
     In yet other embodiment, the peptide composition for hair treatment can comprise at least one aliphatic alcohol selected from the following list: behenyl alcohol, cetearyl alcohol, cetyl alcohol, isocetyl alcohol, isostearyl alcohol, lauryl alcohol, myristyl alcohol, stearyl alcohol, C30-50 alcohols, lanolin alcohol, or any mixture thereof. 
     In another embodiment, the peptide composition for hair treatment can comprise at least one UV filter/sunscreen selected from the following list: benzophenone-(2, 3, 4, 5, 6, 7, 8, 9, or 10), benzophenone-4, benzyl salicylate, benzylidene camphor sulfonic acid, bornelone, ethyl cinnamate, ethylhexyl methoxycinnamate (octyl methoxycinnamate), octoxynol-40, octoxynol-20, octyl methoxycinnamate, octyl salicylate, oxybenzone, phenyl ketone, PEG-25 PABA, polyacrylamidomethyl benzylidene camphor, or any mixture thereof. 
     In other embodiment, the peptide composition for hair treatment can comprise at least one natural oil selected from the following list: coconut oil, jojoba oil, olive oil, palm Oil, safflower oil, sesame seed oil, shea butter, sweet almond oil, wheat germ oil, or any mixture thereof. 
     In yet other embodiment, the peptide composition for hair treatment can comprise at least one amine oxide selected from the following list: cocamine oxide, lauramine oxide, or any mixture thereof. 
     In other embodiment, the peptide composition for hair treatment can comprise at least one chelate selected from the following list: diiospropyl oxalate, disodium EDTA, disodium EDTA-copper, HEDTA, oxalic acid, potassium citrate, sodium citrate, dodium oxalate, TEA-EDTA, tetrasodium EDTA, trisodium EDTA, trisodium HEDTA, or any mixture thereof. 
     In other embodiment, the peptide composition for hair treatment can comprise at least one fatty acid selected from the following list: arichidonic acid, capric acid, coconut fatty acid, lauric acid, linoleic acid, linolenic acid, myristic acid, palmitic acid, pantothenic acid, stearic acid, caproic acid, capryleth-(4, 6, 9) carboxylic acid, isostearic acid, or any mixture thereof. 
     In other embodiment, the peptide composition for hair treatment can comprise at least one agent antimicrobial/antibacterial selected from the following list: glyoxal, triclosan, or any mixture thereof. 
     In other embodiment, the peptide composition for hair treatment can comprise at least one PEG-modified material selected from the following list: PEG-150 pentaerythirtyl tetrastearate, PEG-(-2, -3, -4, -6, -8, -12, -20, -32, -50, -150, -175) distearate, PEG-10 castor oil, PEG-10 cocamine, PEG-10 cocoate, PEG-10 coconut oil esters, PEG-10 glyceryl oleate, PEG-10 glyceryl pibsa tallate, PEG-10 glyceryl stearate, PEG-10 hydrogenated lanolin, PEG-10 hydrogenated tallow amine, PEG-10 isolauryl thioether, PEG-10 isostearate, PEG-10 lanolate, PEG-10 lanolin, PEG-10 laurate, PEG-10 oleate, PEG-10 olive glycerides, PEG-10 polyglyceryl-2 laurate, PEG-10 propylene glycol, PEG-10 sorbitan laurate, PEG-10 soya sterol, PEG-10 soyamine, PEG-10 stearamine, PEG-10 stearate, PEG-10 stearyl benzonium chloride, PEG-10 tallate, PEG-10 tallow aminopropylamine, PEG-100, PEG-100 castor oil, PEG-100 hydrogenated castor oil, PEG-100 lanolin, PEG-100 stearate, PEG-40 hydrogenated castor Oil, PEG-60, PEG-55 propylene glycol distearate, or any mixture thereof. 
     In other embodiment, the peptide composition for hair treatment can comprise at least one polymer selected from the following list: carbomer, dodecanedioic acid/cetearyl alcohol/glycol copolymer, hydrogenated C6-14 olefin polymers, hydrogenated ethylene/propylene/styrene copolymer: polyacrylic acid, polymethyl methacrylate: polymer, polyvinyl acetate, polyvinyl alcohol, PPG, PPG-25-laureth-25, PPG-5 pentaerithrityl ether, PPG-75-PEG-300-hexylene glycol, polyvinylpyrrolidone, PVP/VA (polyvinylpyrrolidone/vinyl acetate copolymer), sodium carbomer, TEA-carbomer, poloxamer (100-407), poloxamine, polyacrylamidomethylpropane sulfonic acid, polyethylene terephthalate, or any mixture thereof. 
     In other embodiment, the peptide composition for hair treatment can comprise at least one antistatic agent selected from the following list: apricotamidopropyl ethyldimonium ethosulfate, apricotamidopropyl ethyldimonium lactate, cocamidopropyl ethyldimonium ethosulfate, cocamidopropyl ethyldimonium lactate, lauramidopropyl ethyldimonium ethosulfate, lauramidopropyl ethyldimonium lactate, linoleamidopropyl ethyldimonium ethosulfate, linoleamidopropyl ethyldimonium lactate, myristamidopropyl ethyldimonium ethosulfate, myristamidopropyl ethyldimonium lactate, oleamidopropyl ethyldimonium ethosulfate, oleamidopropyl ethyldimonium lactate, stearamidopropyl ethyldimonium ethosulfate, stearamidopropyl ethyldimonium lactate, or any mixture thereof. 
     In other embodiment, the peptide composition for hair treatment can comprise at least one alcohol selected from the following list: SD alcohol 40, witch hazel, isopropanol, or any mixture thereof. 
     In yet other embodiment, the peptide composition for hair treatment can comprise fragrances, oils or any mixture thereof. 
     In other embodiment, the peptide composition for hair treatment can be used in medicine, veterinary and/or for cosmetics, preferably for the treatment of hair, mainly for animal or human, particularly for treating diseases of the scalp, particularly scalp irritation, alopecia areata, lichen planus, folliculitis keloid of the neck, trichorrhexis nodosa, tricodistrophy, pili torti, tricorrexis invaginata, moniletrix, uncombable hair syndrome. 
     In other embodiment, the composition may comprise a dye agent linked to the N or C-terminal of the referred peptides. 
     In yet other embodiment is the use of the described composition for hair coloring. 
     Other aspect of the embodiment is the use of the described composition as a hair strengthener or as fixer of perms and/or curly hairs. 
     It is also described in this application shampoo, lotion, serum, cream, conditioner, foam, elixir, oil, aerosol or mask comprising the composition presented in this application. 
     The present application discloses a composition for hair treatment that comprise, in whole or in part, one or more peptide sequences of 6 to 12 amino acid residues based on keratin and keratin-associated proteins having 2 to 5 cysteine residues, preferably having 3 to 5 residues of cysteine, for treatment and cosmetics of the hair, preferably human hair, chemically pre-treated or not. Thus the presence of cysteine in the peptide sequence (higher than 10%, preferably more than 15%) in combination with a percentage of hydrophobic amino acids ensures that the peptides can have a lasting fixation in the hair, improving the human hair properties such as elasticity and strength. 
     Surprisingly, the described peptide compositions in which the peptide(s) comprising 2 to 5 cysteines allow penetration of the peptide(s) and enhance the properties of hair, preferably 3-5 cysteines. Thus, described peptide(s) containing 2-5 cysteine in order to allow hair penetration and enrichment of the hair properties, such as elasticity, resistance, reduce eventual hair damage, as well as improve and change hair characteristics. 
     The peptide compositions described in the present application surprisingly enrich and improve the properties and characteristics of the hair, such as elasticity, strength and appearance, repairing damaged keratinous fiber. Therefore, formulation&#39;s high cysteine content is used to improve and/or change its characteristics, such as hair curl or uncurl. The sequence of peptides can have also preferably a percentage of hydrophobic amino acids not exceeding 60%, improving even further the results. Examples of hydrophobic amino acids are phenylalanine, alanine, leucine, methionine, isoleucine, tryptophan, proline, valine, and others. 
     In the context of the present description, the peptide composition can also be applied to the hair and in particular to the human hair as, but not limited to, aqueous solution or conventional shampoo or conditioner. It can also be used as a lotion, foam, aerosol, gel, mask, and application formulation with or without subsequent rinsing. 
     The concentration of peptide to be used depends on several features such as the condition of the hair, the origin and the formulation of the hair care product. 
    
    
     DETAILED DESCRIPTION 
     It should be understood that the detailed description and specific examples are indicative of preferred embodiments of the invention and are provided to be illustrative only. This patent is not limited to those mentioned applications. 
     The present application describes a composition for hair treatment that comprises different peptides, which are based in the structure of keratin and keratin associated proteins. 
     The compositions described in the present application allow surprisingly the dermo-cosmetic treatment of animal hair, including human hair, chemically pre-treated or not. The composition described in the present invention, through the use of specific peptides, allows the preparation of keratinous fiber damages, due to the high binding capacity of the keratin peptides, including through disulfide bridges. 
     The described compositions improve the properties and characteristics of the hair, such as elasticity, resistance and appearance, repairing putative damages of the hair. 
     The peptides here defined are peptide sequences which bind with a certain affinity to the hair. The peptides used in this invention are composed by 6 to 12 amino acids, and are constituted by a minimum of 2 and a maximum of 5 cysteines, preferably 3-5 cysteines. 
     The peptide composition for hair treatment described allows a resistance increase due to the presence of the cysteine-rich peptide, which leads to the resistance of the hair even after several rinsing. 
     Every peptide can be used together or separately, as well as all or part of the peptide sequence in the hair composition. Each peptide sequence contains amino acids with sulfur, specifically cysteine, which interacts with the hair and allows the formation of intermolecular cross-linking, stabilizing the keratinous fiber. 
     The peptide composition described uses a high content on cysteine in order to enrich the hair properties, such as improve elasticity and resistance, reduce putative damage of the hair, improve and/or change hair characteristics. Regarding the interaction with the keratinous fibers, the cysteine is 10% to 50% of the total amount of amino acids of the peptide sequence. Additionally, the number of amino acids of the peptide sequence is preferable from 6 to 12. 
     The peptides can be used separately or in combination of two or more peptides. The concentration of the peptide to be used depends on several characteristics, such as hair condition, origin and the formulation of the product for hair treatment. The content of the hair composition of the present invention is as example 1-0.001% (w/w) in mass. 
     The peptides of the present invention can be prepared by conventional methods of peptide synthesis, well known in the state of the art. 
     Additionally many companies provide customized services for peptide synthesis. 
     An embodiment of the current invention describes peptides that link to the hair, and which sequence of amino acids includes cysteines where the sequence is selected from the group between the sequences ID NO:1 to sequence ID NO:1239. 
     The sequence of the 1239 peptides referred is listed in the table of the FIG. 1. 
     As example of hair, it was used virgin human hair tresses, acquired from the International Hair Importers and Products, Inc. (New York). The term virgin hair is applied to all the hair that was never subject or was at least 10 years without making any chemical treatment. Several different hair samples such as African, Asian and Caucasian hair are commercially available in several companies, such as the company mentioned above. Optionally, the hair samples can be treated, for example, using hydrogen peroxide to bleach the hair, needed for techniques such as hair dying. 
     In the context of this invention, the peptides can be applied to the hair, such as the human hair in the form of, but not limited to, aqueous or conventional preparation of shampoo or conditioner. It can also be in the form of lotion, foam, spray, gel, mask, formulation applied with or without subsequent rinsing. 
     This invention can be prepared by peptide coupling with an agent of these preparations directly or via a spacer. 
     This coupling interaction can be performed by covalent or non-covalent bonds, such as hydrogen bond, electrostatic interactions, hydrophobic interactions or van der Waals interactions. The spacer can be used to separate the peptide from the preparation agent, ensuring that the agent does not interfere with the peptide linkage to the hair. 
     The present invention can be understood more clearly and accurately by reading the following examples, which are indicative of preferred embodiments of the invention. They are provided for illustration in greater detail of the present invention, without introducing any limitation and without being limited to those applications. 
     EXAMPLES OF APPLICATIONS 
     The examples that are within the scope of the claims represent different embodiments of the invention; all other examples are comparative examples. 
     Example 1 
     The present application treats human hair through several commercial formulations with and without the use of the peptides from the sequence ID NO: 5. As The hair was supplied from International Hair Importers and Products, Inc. (New York). 
     The tests were performed with in human hair after 8 treatments of bleaching, at 50° C. in 0.1 M Na 2 CO 3 /NaHCO 3  buffer, at pH=9, 10% H 2 O 2 , for 1 hour. 
     Several formulations were tested:
         hair serum with 15% PG;   hair mask.       

     The mask used in this application was a basic commercial formulation with water, denaturing alcohol, propylene glycol, ether dicaprylic, cetylstearyl alcohol, behentrimonium chloride, cetyl ester, polysorbate 20, hydrolyzed wheat protein, hydrolyzed wheat starch, benzyl alcohol and fragrance. 
     The hair serum used in this application was a basic commercial formulation with water, denaturing alcohol, propylene glycol, polysorbate 20, hydrolyzed wheat protein, hydrolyzed wheat starch, crosslinked polymer alkyl acrylate/C10-30, triethanolamine, benzyl alcohol, fragrance. 
     Each of the formulations was tested with and without the peptide sequence ID NO:5, which contains in the sequence 15% of cysteine. The formulations containing the peptide SEQ ID NO:5 had a concentration of peptide of 0.1 mg/mL, in a ratio 1:1 (v/v). 
     To demonstrate the effect was also tested:
         a peptide whose sequence does not contain cysteine, with approximately 41% hydrophobic amino acids;   a peptide which contains in it sequence 8% cysteine, with approximately 58% hydrophobic amino acids.       

     The hair mask was applied to the hair after 8 bleaching treatments, being left to act for 15 minutes, mimicking the procedure indicated in commercial masks. Posteriorly, the hair was washed. The serum was applied to the hair after 8 bleaching treatments, being left to act for 1 hour at 37° C. Posteriorly, the hair was not washed, as in typical commercial procedures the serum should be applied in dry hair. The hair was also tested after 5 applications. 
     The peptide from the sequence ID NO: 5 was able to penetrate in the hair fiber for all the formulations. 
     After the treatment, mechanical tests were performed, using a cell with 2.5 N maximum load and a deformation rate of 1.5 mm/min. Each hair was individually mounted in the tensile jig by means of a paper template with a fixed gauge length of 20 mm. 
     
       
         
           
               
             
               
                 TABLE 1 
               
             
            
               
                   
               
               
                 Young modulus of virgin hair without treatments 
               
               
                 and after 8 times bleaching treatments. 
               
            
           
           
               
               
               
            
               
                   
                 Hair type 
                 Young modulus (MPa) 
               
               
                   
                   
               
               
                   
                 Virgin hair 
                 6579 
               
               
                   
                 Hair after 8 time bleaching 
                 5294 
               
               
                   
                 Serum(with a 15% cysteine and 50% 
                 7149 
               
               
                   
                 hydrophobic amino acids peptide) 
               
               
                   
                 Serum for comparison(with a 41% 
                 6180 
               
               
                   
                 hydrophobic amino acid without 
               
               
                   
                 cysteine peptide) 
               
               
                   
                 Serum for comparison 
                 6456 
               
               
                   
                 (with a 8% cysteine and 58% 
               
               
                   
                 hydrophobic amino acid peptide) 
               
               
                   
                 Serum for comparison (without peptide) 
                 6034 
               
               
                   
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 2 
               
             
            
               
                   
               
               
                 Young modulus for different types of hair treatment. The peptide 
               
               
                 in these treatments is the peptide from sequence ID NO: 5. 
               
            
           
           
               
               
               
            
               
                   
                 Young modulus 
                 Young modulus 
               
               
                   
                 after 1 
                 after 5 
               
               
                 Type of treatment 
                 application (MPa) 
                 applications (MPa) 
               
               
                   
               
               
                 Serum (with a 15% cysteine 
                 7149 
                 7318 
               
               
                 and 50% hydrophobic amino 
               
               
                 acid peptide) 
               
               
                 Serum for comparison 
                 6034 
                 6112 
               
               
                 (without peptide) 
               
               
                 Mask (with a 15% cysteine 
                 6175 
                 7075 
               
               
                 and 50% hydrophobic amino 
               
               
                 acid peptide) 
               
               
                 Mask for comparison(without 
                 5514 
                 5685 
               
               
                 peptide) 
               
               
                   
               
            
           
         
       
     
     The formulations which contain the sequence ID NO:5 induce an increase in mechanical resistance of the damaged hair. After 5 applications, the hair treated with the sequence ID NO: 5 maintain the high resistance, having a higher increase in the resistance than without the peptide. 
     Example 2 
     This example discloses the treatment of human hair with peptides containing cysteine, and in this case the peptide containing the sequence ID NO: 409, based in the assumption that small peptides are able to penetrate in the hair fiber cuticle. 
     The hair was supplied from International Hair Importers and Products, Inc. (New York). Hair fibers were pre-treated by bleaching. The formulation was tested in different hair types:
         virgin hair washed, with the cuticle intact and absence of chemical damages;   hair after 8 bleaching treatments, at 50° C. in 0.1 M Na 2 CO 3 /NaHCO 3  buffer, at pH=9, 10% H 2 O 2 , for 1 hour.       

     The incorporation of the peptides was performed by direct application in the hair surface. The mechanical resistance tests were performed after the treatment of the hair with the peptide. 
     The measurements of mechanical resistance were performed using a cell with 2.5 N maximum load and a deformation rate of 1.5 mm/min. Each hair was individually mounted in the tensile jig by means of a paper template with a fixed gauge length of 20 mm. 
     As for the results obtained for the mechanical test showed that compared to the control, i.e., virgin hair without bleaching or peptide treatment (Young modulus: 4142±590 MPa), bleaching reduced the Young modulus (2478±567 MPa), while the treatment with the peptide sequence ID NO: 409 after bleaching increased the Young modulus to higher valued than the virgin hair with no treatment (5649±1022 MPa). 
     Example 3 
     This example discloses the treatment of human hair with a composition comprising peptides. In this example, the peptide with the sequence ID NO: 412 was tested. The hair was supplied from International Hair Importers and Products, Inc. (New York). 
     The formulation was tested in different hair types:
         virgin hair washed, with the cuticle intact and absence of chemical damages;   hair after reduction treatment, at 37° C. in phosphate buffer at pH=8, with 3M GndHCl and 0.05M DTT for 2 hours.       

     For the treatment with the peptide SEQ ID NO: 412, concentrations of 0.01% (w/w) were used. 
     The average of the Young modulus for relaxed hair is 3002 MPa, while for relaxed hair fiber after peptide treatment at 0.01% is 4190 MPa. The Young modulus value for virgin hair without treatment is 5214 MPa. 
     In the maximum load test, for the relaxed hair fiber, the maximum of resistance were 96 MPa, while for the hair fiber relaxed after peptide treatment 126 MPa and for the virgin hair with no treatment 203 MPa. 
     Regarding hair stretching, the relaxed hair has an average of 51%, while after treatment with the peptide sequence ID NO: 412, has a stretching of 72%. For virgin hair, the average of hair stretching is 58%. 
     Therefore, it is evident that the peptides are capable to prevent the hair surface degradation and consequently, the hair treated with these peptides has a longer life span. 
     Example 4 
     In order to assess the interactions between the keratin and some peptides, a keratin solution was prepared. This procedure was performed by immersing African hair, acquired from the International Hair Importers and Products, Inc. (New York), in a solution containing 8 M urea, 0.2 M sodium dodecyl sulfate and 0.5 M sodium bisulfite. The mixture was heated to 50° C. for 24 h in a shaker bath. The solution was dialyzed for several days against double-distilled water. The keratin solution was then concentrated using AMICON with a 3 kDa cut-off. The keratin was then conjugated with Alexa Fluor 647 carboxylic acid, succinimidyl ester in DMSO anhydrous 5%. 
     The reaction was incubated for 1 h 30 min at room temperature and in the dark. The Alexa Fluor 647 that did not link to the keratin solution was separated by centrifugation in AMICON with a 3 kDa cut-off for 1 h at 25° C. and 5000×g. 
     The keratin was then diluted to 1  g/mL in blocking buffer (3% BSA in tris-buffered saline (TBS) with 0.05% Tween 20). The peptides tested were SEQ.ID NO:179, SEQ.ID NO:75, SEQ.ID NO:432, SEQ.ID NO:951, SEQ.ID NO:1108, SEQ.ID NO:1131 and a peptide containing 13 amino acids, including 2 cysteines (X 3 CX 5 CX 3 ), where X represents one of known amino acid residues, with the exception of cysteine residue that is represented by the letter C. This peptide is similar to the one tested in Fernandes et al. (Fernandes, Lima, Loureiro, Gomes, &amp; Cavaco-Paulo, 2012). 
     Several peptides in a concentration of 15 fmol/mm 2 , were attached to a glass through a hydrophilic linked moiety, and were then incubated with the keratin, marked with Alexa Fluor 647, for 2 hours at 37° C. 
     After incubation, the glasses were rinsed in successive washing solutions: TBS+0.1% Tween 20 and blocking buffer with 3% BSA in TBS+0.1% Tween 20, for 3 minutes in each solution. 
     The imaging of the glasses was performed in Agilent G2565CA Microarray Scanner System. Three replicas of the each peptide incubation were performed and analyzed. 
     
       
         
           
               
             
               
                 TABLE 1 
               
             
            
               
                   
               
               
                 Normalized intensity levels of peptide sequences. 
               
            
           
           
               
               
               
               
               
            
               
                   
                 Number of 
                   
                 Hydrophobic 
                 Intensity level 
               
               
                   
                 amino 
                 Cysteine 
                 amino acids 
                 (average ± 
               
               
                 Sequence 
                 acids 
                 content 
                 content 
                 standard deviation) 
               
               
                   
               
               
                 SEQ. ID 
                 10 
                 20% 
                 50% 
                 0.990 ± 0.014 
               
               
                 NO: 179 
               
               
                 SEQ. ID 
                 10 
                 30% 
                 60% 
                 1.000 ± 0.000 
               
               
                 NO: 75 
               
               
                 SEQ. ID 
                 10 
                 30% 
                 40% 
                 1.000 ± 0.000 
               
               
                 NO: 432 
               
               
                 SEQ. ID 
                 10 
                 40% 
                 30% 
                 1.000 ± 0.000 
               
               
                 NO: 951 
               
               
                 SEQ. ID 
                 11 
                 46% 
                 18% 
                 1.000 ± 0.000 
               
               
                 NO: 1108 
               
               
                 SEQ. ID 
                 11 
                 46% 
                  9% 
                 1.000 ± 0.000 
               
               
                 NO: 1131 
               
               
                 X 3 CX 5 CX 3   
                 13 
                 15% 
                 38% 
                 0.184 ± 0.084 
               
               
                   
               
            
           
         
       
     
     The peptides SEQ.ID NO:75, SEQ.ID NO:432, SEQ.ID NO:951, SEQ.ID NO:1108, SEQ.ID NO:1131, with percentage of cysteine ranging from 30% to 46%, such as and percentage of hydrophobic amino acids ranging from 9% to 60% were able to obtain an intensity of 1, indicating a very high affinity to keratin. The peptide SEQ.ID NO:179, with 20% and 50% of cysteine and hydrophobic content, respectively showed an slightly inferior but still very high intensity (0.990±0.014). These peptides were compared with a peptide similar to the one described in Fernandes et al. (Fernandes, Lima, Loureiro, Gomes, &amp; Cavaco-Paulo, 2012) containing 2 cysteines in a 13 amino acids sequence. The reduced percentage of cysteine (15%) and higher number of amino acids in the sequence (13 amino acids) lead to a decrease in the intensity to 0.184±0.084, showing an inferior affinity to keratin. This suggests that the higher number of amino acids difficult the reaction of the peptide with the hair keratins. This inferior affinity to keratin leads to less fixation of the peptides in the hair in posterior treatments and consequently providing less improvements in the recovery of the hair characteristics. 
     List of Peptide Sequences 
     The sequences of peptides are described by one letter code of amino acids. The code is as follows: 
     
       
         
           
               
               
             
               
                   
                   
               
             
            
               
                   
                 Amino acid - One Letter Code 
               
               
                   
                   
               
               
                   
                 Histidine - H 
               
               
                   
                   
               
               
                   
                 Arginine - R 
               
               
                   
                   
               
               
                   
                 Lysine - K 
               
               
                   
                   
               
               
                   
                 Isoleucine - I 
               
               
                   
                   
               
               
                   
                 Phenylalanine - F 
               
               
                   
                   
               
               
                   
                 Leucine - L 
               
               
                   
                   
               
               
                   
                 Tryptophan - W 
               
               
                   
                   
               
               
                   
                 Alanine - A 
               
               
                   
                   
               
               
                   
                 Methionine - M 
               
               
                   
                   
               
               
                   
                 Proline - P 
               
               
                   
                   
               
               
                   
                 Valine - V 
               
               
                   
                   
               
               
                   
                 Cysteine - C 
               
               
                   
                   
               
               
                   
                 Asparagine - N 
               
               
                   
                   
               
               
                   
                 Glycine - G 
               
               
                   
                   
               
               
                   
                 Serine - S 
               
               
                   
                   
               
               
                   
                 Glutamine - Q 
               
               
                   
                   
               
               
                   
                 Tyrosine - Y 
               
               
                   
                   
               
               
                   
                 Threonine - T 
               
               
                   
                   
               
               
                   
                 Aspartic acid - D 
               
               
                   
                   
               
               
                   
                 Glutamic acid - E 
               
               
                   
                   
               
            
           
           
               
               
               
            
               
                   
                 SEQ. ID NO: 1 
                 APCAPRPSCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 2 
                 EACVPSVPCP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 3 
                 ESCGTASGCA 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 4 
                 GLCAGTSACL 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 5 
                 GVCGPSPPCI 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 6 
                 HGCTLPGACN 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 7 
                 HSCTLPGACN 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 8 
                 KDCLQNSLCE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 9 
                 LPCLPAASCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 10 
                 LPCYFTGSCN 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 11 
                 NFCLPSLSCR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 12 
                 NPCATTNACD 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 13 
                 NPCATTNACE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 14 
                 NPCATTNACS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 15 
                 NPCGLRARCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 16 
                 NPCGPRSRCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 17 
                 NPCSTPASCT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 18 
                 NPCSTSPSCV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 19 
                 PACTSSSPCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 20 
                 SKCHESTVCP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 21 
                 SPCVPRTVCV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 22 
                 SSCSVETACL 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 23 
                 SVCSSGVNCR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 24 
                 TACPLPGTCH 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 25 
                 TNCSPRPICV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 26 
                 TSCVPPAPCT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 27 
                 TTCTSSNTCE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 28 
                 VPCVPSVPCT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 29 
                 ATCGPSACIT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 30 
                 GPCISNPCGL 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 31 
                 GPCLSNPCTS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 32 
                 GSCVTNPCGP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 33 
                 LTCFSITCSS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 34 
                 NPCSTPSCTT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 35 
                 PSCVTAPCAP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 36 
                 SDCSSTHCSP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 37 
                 SLCLPPTCHT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 38 
                 SLCNLGSCGP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 39 
                 SPCLVGNCAW 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 40 
                 TACLPGTCAT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 41 
                 TSCLPALCLP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 42 
                 TSCSSRPCVP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 43 
                 TTCGGGSCGV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 44 
                 VNCRPELCLG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 45 
                 YVCQPMACLP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 46 
                 AFSCISACGP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 47 
                 GSVCSAPCNG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 48 
                 GVVCGDLCAS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 49 
                 GVVCGDLCVS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 50 
                 LTGCLLPCYF 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 51 
                 NEDCKLPCNP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 52 
                 NFSCVSACGP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 53 
                 PPTCHTACPL 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 54 
                 PQPCATACKP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 55 
                 SEDCKLPCNP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 56 
                 SLGCRTSCSS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 57 
                 SLSCRTSCSS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 58 
                 SSSCPLGCTM 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 59 
                 TGSCNSPCLV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 60 
                 TSSCPLGCTM 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 61 
                 VGSCGSSCRK 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 62 
                 VGVCGGSCKR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 63 
                 VSNCNWFCEG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 64 
                 ACGPRPGRCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 65 
                 ACGPRPSRCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 66 
                 CAPRPSCGPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 67 
                 CEPCSAYVIC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 68 
                 CGLRARCGPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 69 
                 CGPRPGRCCI 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 70 
                 CGPRPSRCCI 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 71 
                 CGPRSRCGPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 72 
                 CGTSQKGCCN 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 73 
                 CHGCTLPGAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 74 
                 CHSCTLPGAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 75 
                 CLPCLPAASC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 76 
                 CLPPTCHTAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 77 
                 CLSNPCTSCV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 78 
                 CLVGNCAWCE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 79 
                 CNPCSTPASC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 80 
                 CNPCSTPSCT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 81 
                 CNPCSTSPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 82 
                 CNSPCLVGNC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 83 
                 CRTSCSSRPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 84 
                 CSLKEHCSAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 85 
                 CSPRPICVPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 86 
                 CSSTMSYSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 87 
                 CSTPASCTSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 88 
                 CSTPSCTTCV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 89 
                 CTSCVPPAPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 90 
                 CTSSNTCEPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 91 
                 CVPPAPCTPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 92 
                 CVPPSCHGCT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 93 
                 CVPPSCHSCT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 94 
                 DCKLPCNPCA 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 95 
                 DCKLPCNPCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 96 
                 PCGTSQKGCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 97 
                 PCLSNPCTSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 98 
                 PCLVGNCAWC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 99 
                 PCNPCSTPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 100 
                 PCSTPSCTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 101 
                 PCTTCGPTCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 102 
                 PCVPPSCHGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 103 
                 PCVPPSCHSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 104 
                 SCCLPSLGCR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 105 
                 SCSEELQCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 106 
                 SCSPCSTTCT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 107 
                 ASCSTSGTCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 108 
                 ASCYIPVGCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 109 
                 ASCYVPVSCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 110 
                 AVCTLPSSCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 111 
                 DLCPTSVSCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 112 
                 EICWEPTSCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 113 
                 ETCGEPTSCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 114 
                 ETCNETTSCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 115 
                 ETCWRPNSCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 116 
                 GYCGYRPFCF 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 117 
                 KTCWEPASCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 118 
                 KTCWEPTSCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 119 
                 LDCVDTTPCK 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 120 
                 LGCGYGSFCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 121 
                 NSCGYGSGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 122 
                 NYCPSNTMCE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 123 
                 PACVTSYSCR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 124 
                 PDCHVEGTCL 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 125 
                 PDCRVEGTCL 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 126 
                 PICSEPSPCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 127 
                 PICYIFKPCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 128 
                 PLCYISNSCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 129 
                 PPCGQPTPCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 130 
                 PPCHIPQPCV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 131 
                 PSCGRLASCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 132 
                 PSCSESSICQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 133 
                 PSCSEVTSCP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 134 
                 PSCSTSGTCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 135 
                 PSCSVSSGCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 136 
                 PSCTESDSCK 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 137 
                 PSCYQTSSCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 138 
                 PTCFLLNSCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 139 
                 PTCSVTSSCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 140 
                 PTCWLLNNCH 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 141 
                 PTCYQRTSCV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 142 
                 PTCYRRTSCV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 143 
                 PTCYVVKRCP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 144 
                 PVCFEATICE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 145 
                 PVCFEATVCE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 146 
                 PVCSRPASCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 147 
                 PVCSWVPACS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 148 
                 QTCNESSYCL 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 149 
                 QTCWEPTSCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 150 
                 SFCRLGYGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 151 
                 SFCRRGSGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 152 
                 SLCGYGYGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 153 
                 SLCSTEVSCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 154 
                 SNCFGQLNCL 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 155 
                 SPCGQPTPCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 156 
                 SSCDQSSSCA 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 157 
                 SSCGQSSSCA 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 158 
                 SVCPEPVSCP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 159 
                 TFCSFDKSCR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 160 
                 TICSSDKSCR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 161 
                 TLCVESSPCH 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 162 
                 TPCYQQSSCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 163 
                 VICSRQTTCI 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 164 
                 YGCGYGSGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 165 
                 YGCGYGSGCR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 166 
                 YGCIHSTHCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 167 
                 AACEPSACQS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 168 
                 AACEPSPCQS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 169 
                 AACTMSVCSS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 170 
                 ADCLGGICLP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 171 
                 ALCLPSSCHS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 172 
                 ALCSPSTCQL 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 173 
                 APCLALVCAP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 174 
                 APCLSLVCTP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 175 
                 APCLTLVCTP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 176 
                 APCVALLCRP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 177 
                 ASCGSLLCRP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 178 
                 ASCLSFLCRP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 179 
                 ASCVSLLCRP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 180 
                 AVCEPSPCQS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 181 
                 AVCLPVSCQS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 182 
                 AVCVPVRCQS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 183 
                 AVCVPVSCQS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 184 
                 DLCSPSTCQL 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 185 
                 DSCGSSSCGP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 186 
                 DSCVQSNCFP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 187 
                 FNCSTRNCSS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 188 
                 GGCGSYGCSQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 189 
                 GSCGFGSCYG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 190 
                 GSCSSRKCFS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 191 
                 GVCLPSTCPH 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 192 
                 HSCEGYLCYS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 193 
                 IVCAAPSCQS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 194 
                 KTCSTTGCDP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 195 
                 LACVSQPCQS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 196 
                 LGCGYGGCGY 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 197 
                 LSCGSRSCSS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 198 
                 LVCTPVSCVS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 199 
                 NGCQETYCEP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 200 
                 NSCRSLSCGS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 201 
                 PACVISTCPR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 202 
                 PGCLNQSCGS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 203 
                 PPCGTAPCLT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 204 
                 PPCTTALCRP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 205 
                 PPCYLVSCTP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 206 
                 PRCTRPICEP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 207 
                 PSCPVSSCAQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 208 
                 PSCQPSVCVP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 209 
                 PSCSVSNCYQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 210 
                 PSCSVSSCAQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 211 
                 PSCTSVLCRP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 212 
                 PTCKSPSCEP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 213 
                 PTCVISSCPR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 214 
                 PTCVISTCPR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 215 
                 PTCYQTICFR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 216 
                 PVCGGVSCHT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 217 
                 PVCGRVSCHT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 218 
                 PVCNKPVCFV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 219 
                 PVCPTPTCSV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 220 
                 PVCRSTYCVP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 221 
                 PVCSKSVCYV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 222 
                 PVCSRPACYS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 223 
                 PVCYVPTCSE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 224 
                 QFCLSKSCQP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 225 
                 RPCERTACQS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 226 
                 RSCQTSFCGF 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 227 
                 RSCSSLGCGS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 228 
                 RSCYSVGCGS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 229 
                 RVCLPGSCDS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 230 
                 SFCGFPSCST 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 231 
                 SFCGYPSCST 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 232 
                 SGCDPASCQP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 233 
                 SGCGGSGCGG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 234 
                 SGCQPSSCLA 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 235 
                 SHCQPPHCQL 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 236 
                 SICQPATCVA 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 237 
                 SLCVPVSCRP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 238 
                 SNCLPTSCQP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 239 
                 SPCLVSSCQP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 240 
                 SPCQQSSCQE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 241 
                 SPCQQSYCVP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 242 
                 SPCSPAVCVS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 243 
                 SRCQQPSCQP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 244 
                 SRCYRPHCGQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 245 
                 SSCAPIYCRR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 246 
                 SSCAPVYCRR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 247 
                 SSCGKGGCGS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 248 
                 SSCGKRGCGS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 249 
                 SSCLPVSCRP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 250 
                 SSCQPAYCTS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 251 
                 SSCQPSYCRQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 252 
                 SSCQPVVCEP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 253 
                 SSCTAVVCRP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 254 
                 SSCYQPFCRS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 255 
                 SSCYRPICGS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 256 
                 SSCYRPTCGS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 257 
                 SVCMSGSCQA 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 258 
                 SVCSDQGCDQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 259 
                 SVCSDQGCGL 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 260 
                 SVCSDQGCGQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 261 
                 SVCSDQGCSQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 262 
                 SVCSDQSCGQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 263 
                 SVCSHQGCGQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 264 
                 SVCSHQGCGR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 265 
                 SVCVPVSCRP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 266 
                 SYCRQASCVS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 267 
                 TACEPSACQS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 268 
                 TICTASPCQP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 269 
                 TSCPETSCLP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 270 
                 TSCQMTNCEQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 271 
                 TSCQPVHCET 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 272 
                 TSCQPVLCKS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 273 
                 TSCQPVLCVP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 274 
                 TSCVGFVCQP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 275 
                 TSCVSNPCQV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 276 
                 TTCFQPTCVS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 277 
                 TTCFQPTCVT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 278 
                 TTCFQPTCVY 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 279 
                 TTCISNPCST 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 280 
                 TWCQGSSCQP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 281 
                 VGCQSSVCVP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 282 
                 VPCQPSTCVF 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 283 
                 VSCEPSPCQS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 284 
                 VSCGGPICLP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 285 
                 VSCKPVLCVA 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 286 
                 VSCPSTSCRP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 287 
                 VSCQSSVCMP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 288 
                 VSCTRIVCVA 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 289 
                 VTCEPSPCQS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 290 
                 VTCQTTVCRP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 291 
                 YGCGYEGCRY 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 292 
                 AGSCQPSCSE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 293 
                 ALLCRPLCGV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 294 
                 ALVCEPVCLR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 295 
                 ATICEPSCSV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 296 
                 ATTCEPSCSV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 297 
                 ATVCEPSCSV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 298 
                 EGTCLPPCYL 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 299 
                 FSTCRPSCSG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 300 
                 GFVCQPMCSH 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 301 
                 GLDCGYGCGY 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 302 
                 GLGCGYGCGY 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 303 
                 GLGCSYGCGH 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 304 
                 GLGCSYGCGL 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 305 
                 GSGCGYGCGY 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 306 
                 GTGCGYGCGY 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 307 
                 GVSCHTTCYR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 308 
                 GYACNFPCSY 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 309 
                 GYGCGYGCGF 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 310 
                 HSPCQASCYV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 311 
                 HTSCSPACQP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 312 
                 HTSCSSGCQP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 313 
                 IRWCHPDCHV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 314 
                 IRWCRPDCRV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 315 
                 ISSCGTGCGI 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 316 
                 KGGCGSGCGG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 317 
                 KGGCGSSCSQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 318 
                 LVTCQDSCGS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 319 
                 LVTCQESCQP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 320 
                 MSICSSACTD 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 321 
                 MSICSSACTN 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 322 
                 MSVCSSACSD 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 323 
                 PAICEPSCSV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 324 
                 PASCQKSCYR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 325 
                 PIYCRRTCYH 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 326 
                 PNSCQTLCVE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 327 
                 PQPCVPTCFL 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 328 
                 PSACQSGCTS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 329 
                 PSPCEPSCSE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 330 
                 PSPCQASCYI 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 331 
                 PSPCQSGCIS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 332 
                 PSPCQSGCTD 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 333 
                 PSPCQSGCTS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 334 
                 PTACQPTCYQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 335 
                 PTACQPTCYR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 336 
                 PTPCSTTCRT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 337 
                 PTSCQKSCYR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 338 
                 PTSCQPSCES 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 339 
                 PTSCQTSCTL 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 340 
                 PVICEPSCSV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 341 
                 PVSCVPVCSG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 342 
                 PVTCVPRCTR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 343 
                 PVYCRRTCYH 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 344 
                 PVYCRRTCYY 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 345 
                 PVYCVPVCSG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 346 
                 QPGCESPCEP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 347 
                 QQSCVSSCRR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 348 
                 QTSCGSSCGQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 349 
                 QTTCHPSCGM 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 350 
                 QTTCRPSCGV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 351 
                 RGGCGSGCGG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 352 
                 RLACYSLCSG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 353 
                 RPACYRPCYS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 354 
                 RPFCFRRCYS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 355 
                 RPICRPICSG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 356 
                 RPLCYRRCYS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 357 
                 RSPCQASCYV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 358 
                 RVSCHTTCYR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 359 
                 SAICRPTCPR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 360 
                 SDSCKRDCKK 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 361 
                 SEGCGSGCGG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 362 
                 SFLCRPACSR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 363 
                 SGGCGSGCGG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 364 
                 SGGCGSSCGG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 365 
                 SGSCQAACGQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 366 
                 SLLCHPVCKS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 367 
                 SLLCHPVCRS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 368 
                 SLLCRPACSP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 369 
                 SLLCRPACSR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 370 
                 SLLCRPICRP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 371 
                 SLLCRPMCSR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 372 
                 SLLCRPTCSR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 373 
                 SLLCRPVCQP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 374 
                 SLLCRPVCRP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 375 
                 SLLCRPVCRS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 376 
                 SLLCRPVCSR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 377 
                 SNPCQVTCSR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 378 
                 SRGCGSGCGG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 379 
                 SRSCQSPCYR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 380 
                 SRSCQSSCYR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 381 
                 SSGCGYGCGY 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 382 
                 SSGCPMACPG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 383 
                 SSICQPICSE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 384 
                 SSPCHTSCYY 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 385 
                 SSPCQPTCYV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 386 
                 SSPCQQSCYV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 387 
                 SSPCQTSCYR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 388 
                 SSSCQQSCRV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 389 
                 STVCQPACGV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 390 
                 TDNCQETCGE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 391 
                 TQPCYEPCLP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 392 
                 TSSCGTGCGI 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 393 
                 TSSCQPSCGR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 394 
                 TSSCTTPCYQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 395 
                 TSVCLPGCLN 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 396 
                 TTVCLPGCLN 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 397 
                 VANCQAPCST 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 398 
                 VDDCPESCWP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 399 
                 VKRCPSVCPE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 400 
                 VSSCQPSCSE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 401 
                 YEGCRYGCGH 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 402 
                 YGRCRHGCHS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 403 
                 YGYCRPSCYG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 404 
                 YRDCQKTCWE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 405 
                 YRGCQEICWE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 406 
                 YRGCQETCWR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 407 
                 YRGCQQTCWE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 408 
                 YRSCRPSCYG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 409 
                 GGVCGPSPPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 410 
                 GVCGPSPPCI 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 411 
                 VCGPSPPCIT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 412 
                 CGPSPPCITT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 413 
                 CAPIYCRRTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 414 
                 CAPSPCQASC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 415 
                 CAPSPCQPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 416 
                 CAPVYCRRTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 417 
                 CASSPCQQAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 418 
                 CASSSCQPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 419 
                 CASSSCQQSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 420 
                 CCGNFSSHSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 421 
                 CCGYGGLGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 422 
                 CCNYYGNSCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 423 
                 CCNYYRNSCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 424 
                 CCSRNFSSCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 425 
                 CDAGSCQPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 426 
                 CDPCSLQEGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 427 
                 CDPSPCEPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 428 
                 CDPVICEPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 429 
                 CDQGLCQETC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 430 
                 CEATTCEPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 431 
                 CELPCGTPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 432 
                 CEPAICEPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 433 
                 CEPPCGTAPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 434 
                 CEPPCSAPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 435 
                 CEPRSCASSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 436 
                 CEPSACQSGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 437 
                 CEPSCSVSNC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 438 
                 CEPSCSVSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 439 
                 CEPSPCQSGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 440 
                 CEPTACQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 441 
                 CEPTSCQTSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 442 
                 CEPVCLRPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 443 
                 CETSSCQPRC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 444 
                 CETTCFQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 445 
                 CFQPTCVSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 446 
                 CFQPTCVTSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 447 
                 CFQPTCVYSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 448 
                 CGCGFRRLGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 449 
                 CGCGYRGLDC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 450 
                 CGCNGYYGCY 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 451 
                 CGFGSCYGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 452 
                 CGGSGCGGSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 453 
                 CGGSGSSCCV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 454 
                 CGGVSCHTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 455 
                 CGKGGCGSCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 456 
                 CGKRGCGSCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 457 
                 CGQDLCQETC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 458 
                 CGQTSCGSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 459 
                 CGQVLCQETC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 460 
                 CGRDLCQETC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 461 
                 CGRVSCHTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 462 
                 CGSCGFGSCY 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 463 
                 CGSCGGSKGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 464 
                 CGSGCGVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 465 
                 CGSLLCRPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 466 
                 CGSRCYVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 467 
                 CGSSSCGPQC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 468 
                 CGSVCSDQGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 469 
                 CGSVCSDQSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 470 
                 CGSVCSHQGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 471 
                 CGSYGCSQCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 472 
                 CGVCLPSTCP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 473 
                 CGYEGCRYGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 474 
                 CGYGCGYGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 475 
                 CGYGGCGYGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 476 
                 CGYGSFCGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 477 
                 CGYGSGCGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 478 
                 CHPSCGMSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 479 
                 CHPSCSISSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 480 
                 CHPTCYQTIC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 481 
                 CHTSCSPACQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 482 
                 CHTSCSSGCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 483 
                 CHTTCYRPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 484 
                 CHTTCYRPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 485 
                 CIHSPCQASC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 486 
                 CIHSTHCGCN 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 487 
                 CIRSPCQASC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 488 
                 CISSCYRPQC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 489 
                 CISSPCQQSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 490 
                 CKPCSSQSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 491 
                 CKPSCSQSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 492 
                 CKPVCFKPIC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 493 
                 CKPVCYVPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 494 
                 CKPVSCVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 495 
                 CKPVYCVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 496 
                 CKTVYCKPIC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 497 
                 CLNQSCGSNC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 498 
                 CLNQSCGSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 499 
                 CLPGCLNQSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 500 
                 CLPGSCDSCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 501 
                 CLPPCYLVSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 502 
                 CLPTSCQPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 503 
                 CLSFLCRPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 504 
                 CLVSSCQPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 505 
                 CMPSPCQPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 506 
                 CMSGSCQAAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 507 
                 CNESSYCLPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 508 
                 CPASCVSLLC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 509 
                 CPMACPGSPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 510 
                 CPSSCTAVVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 511 
                 CPVTCEPSPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 512 
                 CQAACEPSAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 513 
                 CQAACEPSPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 514 
                 CQAACGQSVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 515 
                 CQAPCSTKNC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 516 
                 CQAVCEPSPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 517 
                 CQDSCGSSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 518 
                 CQHSSCQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 519 
                 CQISSCGTGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 520 
                 CQKSSCQPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 521 
                 CQPMCSHAAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 522 
                 CQPPCTTALC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 523 
                 CQPSCESSFC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 524 
                 CQPSCSESTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 525 
                 CQPSCTSVLC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 526 
                 CQPTCGGSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 527 
                 CQPTCSRPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 528 
                 CQPVCPTPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 529 
                 CQPVLCKSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 530 
                 CQPVVCEPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 531 
                 CQQPSCQPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 532 
                 CQQSCRVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 533 
                 CQQSCYVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 534 
                 CQQSGCQPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 535 
                 CQQSSCHPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 536 
                 CQQSSCKPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 537 
                 CQQSSCQLAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 538 
                 CQQSSCQPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 539 
                 CQQSSCQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 540 
                 CQQSSCQSAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 541 
                 CQQSSCVSCV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 542 
                 CQQSYCVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 543 
                 CQSGCISSCT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 544 
                 CQSGCTDSCT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 545 
                 CQSGCTSSCT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 546 
                 CQSSCYRPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 547 
                 CQSVCYQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 548 
                 CQSVYCQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 549 
                 CQTACEPSAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 550 
                 CQTSSCGTGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 551 
                 CQTTCHPSCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 552 
                 CQTTCRPSCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 553 
                 CQTTCYRTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 554 
                 CQTTRCRTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 555 
                 CQVTCEPSPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 556 
                 CRNTSCQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 557 
                 CRPACSPLAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 558 
                 CRPACSRLAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 559 
                 CRPACSRPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 560 
                 CRPMCSRPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 561 
                 CRPSCGQTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 562 
                 CRPSCGVSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 563 
                 CRPSCSISSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 564 
                 CRPSCSQTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 565 
                 CRPSYCGQSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 566 
                 CRPSYCISSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 567 
                 CRPSYCQTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 568 
                 CRPTCSRLAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 569 
                 CRPTCSSGSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 570 
                 CRPTSCQNTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 571 
                 CRPVCRSTYC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 572 
                 CRPVCSRPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 573 
                 CRPVTCVPRC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 574 
                 CRQSSCQPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 575 
                 CRTTCFHPIC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 576 
                 CRTTCFQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 577 
                 CRTTCYRPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 578 
                 CRTTYCRPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 579 
                 CRVTCEPSPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 580 
                 CRYGCGHRGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 581 
                 CSAPCVALLC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 582 
                 CSDDSGSCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 583 
                 CSEDSSSCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 584 
                 CSEDSYSCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 585 
                 CSEGCGSGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 586 
                 CSESSPSCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 587 
                 CSESSSSCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 588 
                 CSFDKSCRCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 589 
                 CSGASSLCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 590 
                 CSGASSPCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 591 
                 CSGASSSCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 592 
                 CSGASTSCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 593 
                 CSGGCGSGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 594 
                 CSGGCGSSCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 595 
                 CSGISSSCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 596 
                 CSKDSSSCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 597 
                 CSKGACGSCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 598 
                 CSLSCGSRSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 599 
                 CSQDLCQETC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 600 
                 CSRGCGSGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 601 
                 CSRLSSACCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 602 
                 CSSCGKGGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 603 
                 CSSCGKRGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 604 
                 CSSDKSCRCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 605 
                 CSSGNFSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 606 
                 CSSSGCGSFC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 607 
                 CSSSGCGSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 608 
                 CSTPCYQPIC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 609 
                 CSTTCRTSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 610 
                 CSWVPACSCT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 611 
                 CTFSPCQQAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 612 
                 CTMSVCSSAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 613 
                 CTRPICEPCR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 614 
                 CTSSPCQHAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 615 
                 CTSSPCQQAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 616 
                 CTSSPCQQSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 617 
                 CTSSSCQQAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 618 
                 CVALLCRPLC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 619 
                 CVALVCEPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 620 
                 CVFSSCNTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 621 
                 CVGFVCQPMC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 622 
                 CVPRCTRPIC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 623 
                 CVPSPCQVAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 624 
                 CVPSRCQASC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 625 
                 CVPSSCQASC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 626 
                 CVPVCNKPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 627 
                 CVPVCSKSVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 628 
                 CVPVRCKPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 629 
                 CVSLLCRPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 630 
                 CVSLLCRPMC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 631 
                 CVSLLCRPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 632 
                 CVSLLCRPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 633 
                 CVSNPCQVTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 634 
                 CVSRCYRPHC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 635 
                 CVSSCFRPQC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 636 
                 CVSSICQPIC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 637 
                 CVSSPCQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 638 
                 CVVSCTPPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 639 
                 CVVSCTPPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 640 
                 CYCPKNSIFC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 641 
                 CYEPCLPRGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 642 
                 CYRRCYSSCY 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 643 
                 GCCGYGGLGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 644 
                 GCGGCGSGCA 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 645 
                 GCGGCGSGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 646 
                 GCGGCGSSCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 647 
                 GCGGCSSSCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 648 
                 GCGGSGSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 649 
                 GCGSGCAGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 650 
                 GCGSGCGGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 651 
                 GCGSGCGGCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 652 
                 GCGSSCGGCD 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 653 
                 GCGSSCGGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 654 
                 GCGSSCSQCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 655 
                 GCGYSSSCCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 656 
                 GCKGGCGSCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 657 
                 GCSGCSGGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 658 
                 ICSGASSLCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 659 
                 ICSGASSPCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 660 
                 MCCNYYGNSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 661 
                 MCCNYYRNSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 662 
                 MCYGYGCGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 663 
                 NCCSRNFSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 664 
                 PCSLQEGCCR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 665 
                 PCSSQSSCCV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 666 
                 SCCAPASSCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 667 
                 SCCAPASTCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 668 
                 SCCAPTSSCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 669 
                 SCCGYRPLCY 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 670 
                 SCCVPASSCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 671 
                 SCCVPTSSCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 672 
                 SCGCSKGACG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 673 
                 SCGGCDSSCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 674 
                 SCGGCGSGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 675 
                 SCGGCGSSCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 676 
                 SCGGCKGGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 677 
                 SCGGSKGCCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 678 
                 SCGSGCRGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 679 
                 SCYGCGYGCI 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 680 
                 TCCVPVPSCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 681 
                 TCSDDSGSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 682 
                 TCSEDSSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 683 
                 TCSEDSYSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 684 
                 TCSESSPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 685 
                 TCSESSSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 686 
                 TCSKDSSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 687 
                 TCSRLSSACC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 688 
                 VCCQPTPICD 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 689 
                 VCSEDSSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 690 
                 VCSGASSLCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 691 
                 VCSGASSPCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 692 
                 VCSGASSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 693 
                 VCSGASTSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 694 
                 VCSGDSSCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 695 
                 VCSGISSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 696 
                 YCVPIPSCCA 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 697 
                 CASSCCTPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 698 
                 CCDNCPPPCH 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 699 
                 CCEPCLPRGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 700 
                 CCGAASSCCR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 701 
                 CCGCGGSGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 702 
                 CCGPSSSCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 703 
                 CCGSGCGGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 704 
                 CCKPYCSQCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 705 
                 CCMPVSSCCA 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 706 
                 CCNYYRNCCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 707 
                 CCPSCVVSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 708 
                 CCPSYCVSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 709 
                 CCQPICGSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 710 
                 CCQPICVTSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 711 
                 CCQPTCLSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 712 
                 CCQPTCLTSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 713 
                 CCQPTCVASC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 714 
                 CCQPTCVTSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 715 
                 CCQPYCHPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 716 
                 CCQQSSCVSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 717 
                 CCQSSCFKPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 718 
                 CCQSSCSKPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 719 
                 CCQSSCYKPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 720 
                 CCQTICRSTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 721 
                 CCQTTCHPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 722 
                 CCQTTCRPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 723 
                 CCRVPTCSCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 724 
                 CCSPGCQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 725 
                 CCSSGCGSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 726 
                 CCSSSCGSCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 727 
                 CCTQEQNCCE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 728 
                 CCVPIPSCCA 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 729 
                 CCVPISSCCA 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 730 
                 CCVPVCYQCK 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 731 
                 CCVPVPSCCA 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 732 
                 CCVPVPSCCV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 733 
                 CCVPVSSCCA 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 734 
                 CDSSCCQPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 735 
                 CDTCPPPCCK 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 736 
                 CEPCRRPVCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 737 
                 CEPSCCQPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 738 
                 CEPSCCSAVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 739 
                 CETSCCQPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 740 
                 CETTCCRTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 741 
                 CFSGCGSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 742 
                 CGCSQSNCCK 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 743 
                 CGCSQSSCCK 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 744 
                 CGGCGGCGGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 745 
                 CGGCGGGCCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 746 
                 CGGCGSGCCV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 747 
                 CGGCGSSCCV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 748 
                 CGGGCCGSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 749 
                 CGGSCCGSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 750 
                 CGQSCCRPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 751 
                 CGQSCCRPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 752 
                 CGSCGCSQCN 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 753 
                 CGSCGCSQCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 754 
                 CGSFCCQSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 755 
                 CGSGCCVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 756 
                 CGSSCCGSGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 757 
                 CGSSCCQPCY 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 758 
                 CGSSCCQPIC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 759 
                 CGSSCCQPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 760 
                 CGSSCCQSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 761 
                 CGSSCCVPIC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 762 
                 CGSSCCVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 763 
                 CGSSCSQCSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 764 
                 CGYGSCCGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 765 
                 CHPRCCISSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 766 
                 CHPSCCESSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 767 
                 CHPSCCISSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 768 
                 CHPTCCQNTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 769 
                 CHPTCCQTIC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 770 
                 CHPVCCQTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 771 
                 CHPVCKSTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 772 
                 CHPVCRSTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 773 
                 CISSCCHPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 774 
                 CISSCCKPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 775 
                 CISSCCRPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 776 
                 CISSCTPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 777 
                 CISSSCCPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 778 
                 CKAVCCVPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 779 
                 CKPCCSQASC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 780 
                 CKPCCSQSRC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 781 
                 CKPCCSQSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 782 
                 CKPCCSSSGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 783 
                 CKPCSCFSGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 784 
                 CKPCSCSSGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 785 
                 CKPCYCSSGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 786 
                 CKPICCVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 787 
                 CKPQCCQSVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 788 
                 CKPSCCQTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 789 
                 CKPVCCAPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 790 
                 CKPVCCKPIC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 791 
                 CKPVCCKSIC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 792 
                 CKPVCCLPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 793 
                 CKPVCCVPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 794 
                 CKPVCCVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 795 
                 CKPVCCVSTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 796 
                 CKPYCCQSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 797 
                 CKPYCSQCSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 798 
                 CKSNCCKPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 799 
                 CKTVCCKPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 800 
                 CLPPCCVVSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 801 
                 CLTSCCQPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 802 
                 CNPCCSQSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 803 
                 CPESCCELPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 804 
                 CPESCCEPHC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 805 
                 CPESCCEPPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 806 
                 CPFSCPTTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 807 
                 CPGDCFTCCT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 808 
                 CPSCVVSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 809 
                 CPSYCVSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 810 
                 CPTTCCRTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 811 
                 CQETCCRPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 812 
                 CQHACCVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 813 
                 CQNTCCRTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 814 
                 CQPACCQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 815 
                 CQPACCTASC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 816 
                 CQPACCTSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 817 
                 CQPACCTTSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 818 
                 CQPACCVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 819 
                 CQPACCVSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 820 
                 CQPCCHPTCY 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 821 
                 CQPCCRPTSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 822 
                 CQPICCGSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 823 
                 CQPICGSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 824 
                 CQPICVTSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 825 
                 CQPNCCRPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 826 
                 CQPRCCETSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 827 
                 CQPSCCRPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 828 
                 CQPSCCSTPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 829 
                 CQPSCCSTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 830 
                 CQPSCCVPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 831 
                 CQPSCCVSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 832 
                 CQPTCCGSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 833 
                 CQPTCCHPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 834 
                 CQPTCCQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 835 
                 CQPTCCRPRC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 836 
                 CQPTCCRPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 837 
                 CQPTCCRTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 838 
                 CQPTCLSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 839 
                 CQPTCLTSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 840 
                 CQPTCVASCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 841 
                 CQPTCVTSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 842 
                 CQPVCCQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 843 
                 CQPYCHPTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 844 
                 CQQACCMPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 845 
                 CQQACCVPIC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 846 
                 CQQACCVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 847 
                 CQQSCCVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 848 
                 CQQSCCVSVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 849 
                 CQSMCCQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 850 
                 CQSNCCVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 851 
                 CQSSCCKPCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 852 
                 CQSSCCQSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 853 
                 CQSSCCVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 854 
                 CQSSCFKPCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 855 
                 CQSSCSKPCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 856 
                 CQSVCCQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 857 
                 CQTICRSTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 858 
                 CQTTCCRPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 859 
                 CQTTCCRTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 860 
                 CRATCCRPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 861 
                 CRGCGPSCCA 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 862 
                 CRPACCETTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 863 
                 CRPACCQNTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 864 
                 CRPCCWATTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 865 
                 CRPICRPACC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 866 
                 CRPLCCQTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 867 
                 CRPQCCQSVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 868 
                 CRPQCCQTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 869 
                 CRPRCCISSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 870 
                 CRPSCCESSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 871 
                 CRPSCCETTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 872 
                 CRPSCCISSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 873 
                 CRPSCCKPQC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 874 
                 CRPSCCMSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 875 
                 CRPSCCQTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 876 
                 CRPSCCRPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 877 
                 CRPSCCVSRC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 878 
                 CRPSCCVSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 879 
                 CRPTCCETTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 880 
                 CRPTCCQNTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 881 
                 CRPTCCQTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 882 
                 CRPVCCDPCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 883 
                 CRPVCCQTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 884 
                 CRPVCQPACC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 885 
                 CRPVCRPACC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 886 
                 CRPVCRPTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 887 
                 CRPVCRSTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 888 
                 CRPYCCESSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 889 
                 CRRPVCCDPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 890 
                 CRSQCCQSVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 891 
                 CRTTCCHPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 892 
                 CRTTCCQPIC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 893 
                 CRTTCCQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 894 
                 CRTTCCRPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 895 
                 CRTTCCRTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 896 
                 CSCSSCGSCA 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 897 
                 CSCSSCGSCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 898 
                 CSCTSCGSCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 899 
                 CSPACQPTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 900 
                 CSPGCQPTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 901 
                 CSPSCCQTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 902 
                 CSQCSCYKPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 903 
                 CSQSNCCKPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 904 
                 CSQSSCCKPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 905 
                 CSSGCGSCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 906 
                 CSSGCGSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 907 
                 CSSGCQPACC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 908 
                 CSSSCCQPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 909 
                 CSTPCCQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 910 
                 CSTTCCQPIC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 911 
                 CTAVVCRPCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 912 
                 CTDSCTPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 913 
                 CTPSCCQPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 914 
                 CTRPICEPCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 915 
                 CTSSCTPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 916 
                 CVPACSCSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 917 
                 CVPACSCTSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 918 
                 CVPVCCKPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 919 
                 CVPVCCVPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 920 
                 CVPVCCVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 921 
                 CVSCVSSPCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 922 
                 CVSRCCRPQC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 923 
                 CVSSCCKPQC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 924 
                 CVSSCCQHSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 925 
                 CVSSCCQPFC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 926 
                 CVSSCCQPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 927 
                 CVSSCCRPQC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 928 
                 CVSTCCRPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 929 
                 CVTRCCSTPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 930 
                 CVTSCCQPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 931 
                 CVTSCCQPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 932 
                 CVYSCCQPFC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 933 
                 CVYSCCQPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 934 
                 GCCGCSEGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 935 
                 GCCGCSGGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 936 
                 GCCGCSRGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 937 
                 GCCRPITCCP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 938 
                 GCGSSCCQCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 939 
                 GCGVPVCCCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 940 
                 LCCPCQTTCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 941 
                 PCCCLRPVCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 942 
                 PCCCRPVTCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 943 
                 PCCCVRPVCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 944 
                 PCCSQASCCV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 945 
                 PCCSQSRCCV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 946 
                 PCCSQSSCCK 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 947 
                 PCCSQSSCCV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 948 
                 PCCWATTCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 949 
                 QCSCCKPYCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 950 
                 RCYVPVCCCK 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 951 
                 SCCAPVYCCK 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 952 
                 SCCISSSCCP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 953 
                 SCCVSSCRCP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 954 
                 SCGCSQCSCY 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 955 
                 SCGLENCCCP 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 956 
                 VCCGASSCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 957 
                 VCCGDSSCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 958 
                 CASSCCTPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 959 
                 CCCPSCVVSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 960 
                 CCCPSYCVSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 961 
                 CCCSSGCGSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 962 
                 CCDTCPPPCCK 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 963 
                 CCEPHCCALSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 964 
                 CCEPPCCAPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 965 
                 CCEPPCCATSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 966 
                 CCETSCCQPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 967 
                 CCGSSCCGSGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 968 
                 CCGSSCCGSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 969 
                 CCHPRCCISSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 970 
                 CCHPSCCESSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 971 
                 CCHPSCCISSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 972 
                 CCHPSCCVSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 973 
                 CCHPTCCQNTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 974 
                 CCHPTCCQTIC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 975 
                 CCISSCCKPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 976 
                 CCISSCCRPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 977 
                 CCISSSCCPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 978 
                 CCKAVCCVPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 979 
                 CCKPCCSQASC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 980 
                 CCKPCCSQSRC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 981 
                 CCKPCCSQSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 982 
                 CCKPCCSSSGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 983 
                 CCKPCSCFSGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 984 
                 CCKPCSCSSGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 985 
                 CCKPCYCSSGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 986 
                 CCKPICCVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 987 
                 CCKPQCCQSVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 988 
                 CCKPVCCKPIC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 989 
                 CCKPYCCQSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 990 
                 CCKPYCSQCSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 991 
                 CCMPVCCKPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 992 
                 CCMPVCCKTVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 993 
                 CCMSSCCKPQC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 994 
                 CCNPCCSQSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 995 
                 CCPGDCFTCCT 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 996 
                 CCPSCVVSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 997 
                 CCPSYCVSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 998 
                 CCQNTCCRTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 999 
                 CCQPACCVSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1000 
                 CCQPCCHPTCY 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1001 
                 CCQPCCRPTSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1002 
                 CCQPICGSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1003 
                 CCQPICVTSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1004 
                 CCQPNCCRPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1005 
                 CCQPSCCETSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1006 
                 CCQPSCCRPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1007 
                 CCQPSCCSTPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1008 
                 CCQPSCCSTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1009 
                 CCQPSCCVPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1010 
                 CCQPSCCVSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1011 
                 CCQPTCCHPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1012 
                 CCQPTCCQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1013 
                 CCQPTCCRPRC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1014 
                 CCQPTCCRPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1015 
                 CCQPTCCRPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1016 
                 CCQPTCCRTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1017 
                 CCQPTCLSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1018 
                 CCQPTCLTSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1019 
                 CCQPTCVASCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1020 
                 CCQPTCVTSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1021 
                 CCQPYCHPTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1022 
                 CCQSMCCQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1023 
                 CCQSNCCVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1024 
                 CCQSSCCKPCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1025 
                 CCQSSCCKPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1026 
                 CCQSSCCKPYC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1027 
                 CCQSSCCQSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1028 
                 CCQSSCCVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1029 
                 CCQSSCFKPCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1030 
                 CCQSSCSKPCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1031 
                 CCQSSCYKPCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1032 
                 CCQSVCCQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1033 
                 CCQTICRSTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1034 
                 CCQTTCCRPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1035 
                 CCQTTCCRTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1036 
                 CCRPACCETTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1037 
                 CCRPACCQNTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1038 
                 CCRPLCCQTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1039 
                 CCRPQCCQSVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1040 
                 CCRPQCCQTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1041 
                 CCRPSCCESSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1042 
                 CCRPSCCETTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1043 
                 CCRPSCCGSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1044 
                 CCRPSCCISSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1045 
                 CCRPSCCKPQC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1046 
                 CCRPSCCQTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1047 
                 CCRPSCCVSRC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1048 
                 CCRPSCCVSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1049 
                 CCRPTCCQNTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1050 
                 CCRPTCCQTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1051 
                 CCRPVCCDPCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1052 
                 CCRTTCCQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1053 
                 CCRTTCCRPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1054 
                 CCRTTCCRTTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1055 
                 CCSCSSCGSCA 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1056 
                 CCSPGCQPTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1057 
                 CCSQSSCCKPC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1058 
                 CCSSGCGSCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1059 
                 CCSSGCGSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1060 
                 CCSTPCCQPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1061 
                 CCVPACSCSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1062 
                 CCVPACSCTSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1063 
                 CCVPICCKPIC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1064 
                 CCVPICCKPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1065 
                 CCVPVCCKPIC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1066 
                 CCVPVCCKPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1067 
                 CCVPVCCKSNC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1068 
                 CCVPVCCKTVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1069 
                 CCVPVCCSSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1070 
                 CCVPVCCVPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1071 
                 CCVSSCCKPQC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1072 
                 CCVSSCCQHSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1073 
                 CCVSSCCQPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1074 
                 CCVSSCCRPQC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1075 
                 CCVSTCCRPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1076 
                 CCVSVCCKPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1077 
                 CDSSCCQPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1078 
                 CEPCCRPVCCD 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1079 
                 CFKPCCCQSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1080 
                 CGDGCCCPSCY 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1081 
                 CGGGCCGSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1082 
                 CGGSCCGSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1083 
                 CGLENCCCPSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1084 
                 CGQSCCRPACC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1085 
                 CGQSCCRPVCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1086 
                 CGSCCQSSCCN 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1087 
                 CGSCGCSQCNC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1088 
                 CGSCGCSQCSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1089 
                 CGSGCCGPVCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1090 
                 CGSGCCVPVCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1091 
                 CGSNCCQPCCR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1092 
                 CGSSCCQPCCH 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1093 
                 CGSSCCQPCCR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1094 
                 CGSSCCQPCYC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1095 
                 CGSSCCQPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1096 
                 CGSSCCQSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1097 
                 CGSSCCVPICC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1098 
                 CGSSCCVPVCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1099 
                 CGSSCSQCSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1100 
                 CGVPVCCCSCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1101 
                 CHPRCCISSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1102 
                 CHPSCCESSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1103 
                 CHPSCCISSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1104 
                 CHPTCCQNTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1105 
                 CISSCCHPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1106 
                 CISSCCKPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1107 
                 CISSCCRPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1108 
                 CISSSCCPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1109 
                 CKPCCCSSGCG 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1110 
                 CKPCCSQASCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1111 
                 CKPCCSQSRCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1112 
                 CKPCCSQSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1113 
                 CKPQCCQSMCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1114 
                 CKPQCCQSVCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1115 
                 CKPVCCCVPAC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1116 
                 CKPVCCKPICC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1117 
                 CKPVCCMPVCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1118 
                 CKPVCCVPVCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1119 
                 CKPVCCVSVCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1120 
                 CKPYCSQCSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1121 
                 CLPCCRPTCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1122 
                 CLTSCCQPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1123 
                 CMSSCCKPQCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1124 
                 CNPCCSQSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1125 
                 CPACCVSSCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1126 
                 CPESCCEPHCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1127 
                 CPESCCEPPCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1128 
                 CPSCCESSCCR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1129 
                 CPSCCQTTCCR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1130 
                 CPSCCVSSCCR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1131 
                 CQCSCCKPYCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1132 
                 CQETCCRPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1133 
                 CQNTCCRTTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1134 
                 CQPACCTASCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1135 
                 CQPACCTSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1136 
                 CQPACCTTSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1137 
                 CQPACCVPVCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1138 
                 CQPACCVSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1139 
                 CQPCCHPTCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1140 
                 CQPCCRPACCE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1141 
                 CQPCCRPACCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1142 
                 CQPCCRPTCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1143 
                 CQPCYCPACCV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1144 
                 CQPICCGSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1145 
                 CQPRCCETSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1146 
                 CQPSCCETSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1147 
                 CQPSCCRPACC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1148 
                 CQPSCCVPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1149 
                 CQPSCCVSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1150 
                 CQPTCCCPSYC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1151 
                 CQPTCCGSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1152 
                 CQPTCCHPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1153 
                 CQPTCCQPTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1154 
                 CQPTCCRPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1155 
                 CQPTCCRPTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1156 
                 CQPTCCRTTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1157 
                 CQQACCMPVCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1158 
                 CQQACCVPICC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1159 
                 CQQACCVPVCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1160 
                 CQQSCCVPVCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1161 
                 CQQSCCVSVCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1162 
                 CQSNCCVPVCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1163 
                 CQSSCCCPASC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1164 
                 CQSSCCKPCCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1165 
                 CQSSCCKPCSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1166 
                 CQSSCCKPYCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1167 
                 CQSSCCNPCCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1168 
                 CQSSCCQSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1169 
                 CQSSCCVPVCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1170 
                 CQSSCFKPCCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1171 
                 CQSSCSKPCCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1172 
                 CQSSCYKPCCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1173 
                 CQSVCCQPTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1174 
                 CQTTCCCPSCV 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1175 
                 CQTTCCRPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1176 
                 CQTTCCRTTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1177 
                 CRPACCETTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1178 
                 CRPACCQNTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1179 
                 CRPCCCLRPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1180 
                 CRPCCCVRPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1181 
                 CRPCCWATTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1182 
                 CRPLCCQTTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1183 
                 CRPQCCQSVCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1184 
                 CRPQCCQTTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1185 
                 CRPRCCISSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1186 
                 CRPSCCESSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1187 
                 CRPSCCISSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1188 
                 CRPSCCKPQCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1189 
                 CRPSCCPSCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1190 
                 CRPSCCQTTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1191 
                 CRPSCCRPQCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1192 
                 CRPSCCVSRCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1193 
                 CRPSCCVSSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1194 
                 CRPTCCQNTCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1195 
                 CRPVCCCEPTC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1196 
                 CRPVCCCYSCE 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1197 
                 CRTTCCHPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1198 
                 CRTTCCRPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1199 
                 CSCCKPYCSQC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1200 
                 CSKPCCCQSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1201 
                 CSPCCQPTCCR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1202 
                 CSPCCVSSCCQ 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1203 
                 CSQCSCCKPCY 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1204 
                 CSQCSCYKPCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1205 
                 CSQSNCCKPCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1206 
                 CSQSSCCKPCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1207 
                 CSSSCCQPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1208 
                 CTPSCCQPACC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1209 
                 CVASCCQPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1210 
                 CVPICCCKPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1211 
                 CVPSCCQPCCH 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1212 
                 CVPVCCCKPMC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1213 
                 CVPVCCCKPVC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1214 
                 CVPVCCKPVCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1215 
                 CVSSCCKPQCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1216 
                 CVSSCCQHSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1217 
                 CVSSCCQPCCH 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1218 
                 CVSSCCQPCCR 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1219 
                 CVSSCCQPFCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1220 
                 CVSSCCQPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1221 
                 CVSSCCRPQCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1222 
                 CVTRCCSTPCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1223 
                 CVTSCCQPACC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1224 
                 CVTSCCQPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1225 
                 CVYSCCQPFCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1226 
                 CVYSCCQPSCC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1227 
                 CYCPACCVSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1228 
                 CYKPCCCQSSC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1229 
                 CYKPCCCSSGC 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1230 
                 MCCCVPACSCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1231 
                 NCCVPVCCQCK 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1232 
                 QCSCCKPCYCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1233 
                 QCSCYKPCCCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1234 
                 SCCVPICCQCK 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1235 
                 SCCVPVCCQCK 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1236 
                 SCGCSQCNCCK 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1237 
                 SCGCSQCSCCK 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1238 
                 VCCCVPACSCS 
               
               
                   
                   
               
               
                   
                 SEQ. ID NO: 1239 
                 VCCCVPACSCT 
               
               
                   
                   
               
            
           
         
       
     
     The present invention is of course in any way restricted to the embodiments herein described and one with ordinary skill in the area can provide many possibilities to modifications and substitutions of technical characteristics by equivalent ones, depending on each situation, as defined in the claims. 
     The preferred embodiments described above may obviously be combined. The following claims define further preferred embodiments.