Patent Publication Number: US-2007101549-A1

Title: Yarn arrangement device and method for yarn arrangement using the device, yarn arrangement tool, method of manufacturing yarn arranged body, and method of manufacturing living body-related substance immobilizing micro array

Description:
BACKGROUND OF THE INVENTION  
      1. Field of the Invention  
      The present invention relates to a fiber array device for arraying a plurality of fibers three dimensionally, a fiber array method that uses this device, and a fiber wound object and fiber array body obtained by arraying fibers using this method. The present invention also relates to a jig for arraying a plurality of fibers three-dimensionally and a method of manufacturing a fiber array body that uses this jig. Furthermore, the present invention relates to a method of manufacturing from the fiber array body a microarray to which organism related substance has been fixed that is used to examine and detect specific organism related substance.  
      2. Description of Related Art  
      An analysis method known as the DNA microarray method (also known as the DNA chip method) is known as a method of performing collective expression analysis of multiple genes.  
      In this method, using a flat substrate piece that is known as a microarray or chip (referred to below as a DNA microarray) on which a number of DNA fragments have been arrayed at a high density and also fixed in position, the detection and quantification of nucleic acids based on inter nucleic acid hybridization reactions is performed on the individual fixed DNA fragments.  
      Using this method, the reaction sample only needs to be very small, and a large variety of reaction specimens can be analyzed and quantified rapidly and statistically with excellent repeatability.  
      An example of a specific DNA microarray method is a method in which a sample is taken of the expressed genes of cells or the like being researched that have been identified using fluorescent dye or the like, and, by then performing hybridization on this sample on a DNA microarray, complementary nucleic acids (DNA or RNA) are bonded together. These bond locations are then read using a suitable fluorescence detector.  
      According to this method, the respective gene quantities in the sample can be measured quickly.  
      An example of technology for fixing an organism related substance such as nucleic acids on a microarray is a method that, as is described in Japanese Patent Application Unexamined Publication No. 2001-239594, uses fiber as a fixed carrier for organism related substance.  
      In this method, firstly, a fiber array body in which a plurality of fibers, which are fixed carriers, have been arrayed three-dimensionally in an orderly manner is prepared. This fiber array body is then sliced into thin pieces. As a result, microarrays in the form of thin pieces on which fibers are arrayed two-dimensionally at high density are obtained. In addition, here, in order to manufacture a fiber array body on which a plurality of fibers have been arrayed systematically, a plurality of jigs that have holes in the same pattern as the desired array pattern are used together.  
      Specifically, firstly, these jigs are laid out such that the positions of the holes are lined up in mutual contact. Fibers, which are fixed carriers for organism related substance, are then made to penetrate respectively those holes in the jigs that are in the same positional relationship. Next, the gap between the jigs is increased so that tension is imparted to the respective fibers that are arrayed three-dimensionally between the jigs, and the fibers are aligned. The gaps between the fibers are then filled using hardening resin and the fibers are fixed when the resin hardens.  
      The fiber array body that is obtained by fixing the resin in this manner is then sliced perpendicularly to the longitudinal direction of the fibers. As a result, an organism related substance fixed microarray is obtained. Note that, here, it is also possible to fix organism related substance in the fibers in advance. It is also possible to align a plurality of fibers and, after these fibers have been fixed by resin or the like, fix organism related substance to each fiber.  
      According to this method, it is possible to simultaneously manufacture a large number of organism related substance fixed microarrays in the same array.  
      On the other hand, there is also a need for organism related substance fixed microarrays that have a large number of fibers per unit surface area, namely, that have a large number of types of fixed organism related substance per unit area. In order to increase the number of fibers, it is necessary to reduce the array spacing (i.e., the array pitch) between fibers. Furthermore, there are demands for the outer diameter of the fibers to be made more narrow and also for the diameter of the holes into which the fibers are inserted to be made smaller.  
      However, in the method described in Japanese Patent Application Unexamined Publication No. 2001-239594, as is described above, a plurality of jigs in which a large number of holes have been formed are used, and it is necessary to insert a single fiber through each one of the holes. Accordingly, if the array pitch, hole diameter, and fiber outer diameter are reduced in size, the following problems occur.  
      Namely, in the procedure to guide a fiber that is to be inserted into a hole to a hole, and in the procedure to insert the fiber and the like, normally, minute forceps and nozzles are used to move the fibers. However, at such times, fibers that have already been inserted in adjacent holes tend to obstruct the operation of the forceps and nozzles. This tendency is particularly noticeable when the array pitch, hole diameter, and fiber outer diameter are made smaller. Moreover, if the outer diameter of the fibers is reduced in size, there is a deterioration in the fiber rigidity, and the problem arises that inserting the fibers in the holes is made even more difficult.  
      As is described above, in a conventional process to manufacture a fiber array body that uses fibers as a carrier for fixing organism related substance, it is difficult to array the fibers at a high density with any degree of efficiency and, in large volume industrial production in particular, this lack of efficiency is a major problem.  
      As a result of repeated thorough investigations in light of the above described circumstances, the present inventors discovered that, when manufacturing a fiber array body that uses fibers as carriers for fixing organism related substance, by using a specific device and jig for arraying fibers, it is possible to manufacture fiber arrayed bodies extremely efficiently in which the fibers are arrayed at a high density and with great precision, and thus realized the present invention. Accordingly, it is an object of the present invention to provide a fiber array device and a fiber array jig that enable fiber arrayed bodies and the like to be manufactured extremely efficiently, at a high density, and with great precision.  
     SUMMARY OF THE INVENTION  
      In order to solve the above described problems, the present invention is a fiber array device for arraying fibers three-dimensionally, that comprises: a fiber winding device onto which a fiber is wound; and a fiber supply device that supplies the fiber to the fiber winding device, wherein the fiber supply device is provided with a movable guide that supplies fiber to the fiber winding device while undergoing relative displacement, and wherein the fiber winding device has a fiber winding bobbin that winds fiber onto its circumference as it rotates, and fiber array flat plates a plurality of which are stacked respectively at a plurality of predetermined positions on the circumference of the fiber winding bobbin and on whose respective external surfaces the fibers are arrayed.  
      It is preferable that a plurality of concave rows in which fibers are individually arrayed are formed substantially parallel with each other in an external surface of the fiber array flat plates, and that the fiber array flat plates are stacked on the circumference such that the concave rows are perpendicular to a rotation shaft of the fiber winding bobbin.  
      It is also possible for an array pitch of fibers that are arrayed on external surfaces of the fiber array flat plates making up at least one stacked object from among each of the stacked objects in the plurality of predetermined positions to be different from an array pitch of fibers that are arrayed on external surfaces of the fiber array flat plates making up the other stacked objects.  
      It is preferable that at least two positioning through holes are formed in the fiber array flat plates, and that supporting columns that are inserted through the positioning through holes are provided on the circumference of the fiber winding bobbin.  
      The fiber array method of the present invention is a method for arraying fibers three-dimensionally using the above described fiber array device that comprises: a first step in which the individual fiber array flat plates are arranged in the plurality of predetermined positions; a second step in which the fiber winding bobbin is rotated a predetermined number of times, and fiber is supplied while the movable guide is being moved so that the fibers are gradually arrayed on the arranged fiber array flat plates; and a third step in which the other fiber array flat plates are each stacked on top of each fiber array flat plate on which fibers have been arrayed, wherein the second step and third step are repeated a plurality of times.  
      It is preferable that the fibers are at least one selected from a group consisting of synthetic fibers, semi-synthetic fibers, regenerated fibers, inorganic fibers, and natural fibers.  
      The method of manufacturing a fiber array body of the present invention is a method in which the fibers that have been arrayed three-dimensionally using the above described fiber array method are fixed. At this time, it is preferable that a curable resin is used to fill gaps between the fibers and is then cured so as to fix the fibers.  
      It is also possible for organism related substance to be fixed in advance to the fibers, and it is also possible to fix organism related substance to fixed fibers.  
      The method of manufacturing a microarray in which organism related substance has been fixed of the present invention is a method in which the fiber array body is sliced into thin pieces in a direction intersecting the fibers.  
      A fiber wound object of the present invention comprises: a fiber winding device that has a fiber winding bobbin and stacked objects made up of two or more fiber array flat plates that have each been stacked at a plurality of predetermined positions on the circumference of the fiber winding bobbin; and fibers that are arrayed and wound onto an external surface of each fiber array flat plate.  
      It is also possible for an array pitch of fibers that are arrayed on external surfaces of the fiber array flat plates making up at least one stacked object from among each of the stacked objects in the plurality of predetermined positions to be different from an array pitch of fibers that are arrayed on external surfaces of the fiber array flat plates making up the other stacked objects.  
      Furthermore, in order to solve the above described problems, the present invention is a fiber array jig for arraying a plurality of fibers three-dimensionally, that comprises: a plurality of fiber array flat plates on one surface of each of which a plurality of concave rows in which fibers are individually arrayed are formed substantially parallel with each other; and a positioning member that is used to place these fiber array flat plates in predetermined positions, wherein at least two of the fiber array flat plates are placed apart from each other by the positioning member such that the concave rows formed on these fiber array flat plates are in alignment with each other, and one or more of the other fiber array flat plates is stacked on top of these fiber array flat plates.  
      It is preferable that at least two positioning through holes are formed in each of the fiber array flat plates, and that the positioning member is provided with supporting columns that place each fiber array flat plate in a predetermined position by being inserted through each of the positioning through holes.  
      The method of manufacturing a fiber arrayed body of the present invention is a method that comprises: a fiber array step in which a plurality of fibers are arrayed three-dimensionally using the above described fiber array jig; and a fiber fixing step in which the three-dimensionally arrayed fibers are fixed.  
      An example of a first mode of the above described fiber array step is a method that comprises: a first step in which at least two of the fiber array flat plates are placed apart from each other by the positioning member such that the concave rows formed on these fiber array flat plates are in alignment with each other; a second step in which fibers are individually arrayed so as to span completely across the concave rows that are positioned in alignment with each other; a third step in which other fiber array flat plates are stacked respectively on top of the at least two fiber array flat plates; and a fourth step in which tension is imparted to the arrayed fibers, wherein each of the second step through fourth step is repeated a plurality of times.  
      An example of a second mode of the above described fiber array step is a method that comprises: a first step in which at least one of the fiber array flat plates is placed in a predetermined position by the positioning member; a second step in which a fiber array flat plate that has completed fiber bonding is manufactured by arraying and bonding one by one ends on one side of fibers that have been cut to a predetermined length in the concave rows in the other one of the fiber array flat plates; a third step in which ends on the other side of the arrayed and bonded fibers are arrayed one by one in the concave rows of the fiber plate that was placed in the predetermined position; a fourth step in which another fiber array flat plate is stacked by the positioning member on top of the fiber array flat plate that was placed in the predetermined position; a fifth step in which the fiber array flat plate that has completed fiber bonding is placed apart by the positioning member from the fiber array flat plate that was placed in the predetermined position such that the concave rows formed on the fiber array flat plate that has completed fiber bonding are in alignment with the concave rows formed on the fiber array flat plate that was placed in the predetermined position; and a sixth step in which tension is imparted to the arrayed fibers, wherein each of the second step through sixth step is repeated a plurality of times.  
      The second step of the above second mode preferably comprises a step in which the fiber array flat plates are mounted on drum faces of a fiber winding drum that rotates around a shaft and are rotated, and fiber is continuously supplied to the fiber winding drum so that the fibers are arrayed in sequence in the plurality of concave rows that are formed in the fiber array flat plates, and thereafter the arrayed fibers are cut off outside the fiber array flat plates.  
      It is preferable that the fibers are at least one selected from a group consisting of synthetic fibers, semi-synthetic fibers, regenerated fibers, inorganic fibers, and natural fibers.  
      In the fiber fixing step, it is preferable that a curable resin is used to fill gaps between the three-dimensionally arrayed fibers and is then cured.  
      Moreover, it is preferable that organism related substance is fixed in advance to the fibers, or that, after the fiber fixing step, organism related substance is fixed to the fibers.  
      The method of manufacturing a microarray in which organism related substance has been fixed of the present invention is a method in which a fiber array body manufactured using the above described method is sliced into thin pieces in a direction intersecting the fibers. 
    
    
     BRIEF DESCRIPTION OF THE DRAWINGS  
       FIG. 1  is a perspective view showing an example of the fiber array device of the present invention.  
       FIG. 2  is an enlarged perspective view of a movable guide provided in the fiber array device shown in  FIG. 1 .  
       FIG. 3A  is a perspective view and  FIG. 3B  is a frontal view of a fiber winding bobbin provided in the fiber array device shown in  FIG. 1 .  
       FIG. 4A  is a perspective view of a precise pitch flat plate and  FIG. 4B  is a perspective view of an enlarged pitch flat plate provided in the fiber array device shown in  FIG. 1 .  
       FIG. 5  is a frontal view showing a state in which the fiber array flat plates shown in  FIGS. 4A and 4B  are positioned and stacked in predetermined positions on the circumference of the fiber winding bobbin shown in  FIGS. 3A and 3B .  
       FIG. 6  is a frontal view showing an example of a fiber wound object of the present invention.  
       FIG. 7  is a perspective view showing an example of a fiber array body manufactured using the present invention.  
       FIG. 8  is a perspective view showing an example of an organism related substance fixed microarray manufactured using the present invention.  
       FIG. 9  is a perspective view showing an example of a potting block used in the present invention.  
       FIG. 10  is an explanatory view illustrating a method of manufacturing a fiber array body of the present invention.  
       FIG. 11  is an explanatory view illustrating a method of manufacturing a fiber array body of the present invention.  
       FIG. 12  is a perspective view showing one method of introducing organism related substance into each fiber of a fiber array body.  
       FIG. 13  is a perspective view showing an example of a fiber array jig of the present invention.  
       FIG. 14A  is a perspective view showing a fiber array flat plate and  FIG. 14B  is a perspective view showing a positioning member forming the fiber array jig shown in  FIG. 13 .  
       FIG. 15  is a perspective view showing another example of the fiber array jig of the present invention.  
       FIG. 16  is a perspective view showing an example of a fiber array body manufactured using the present invention.  
       FIG. 17  is a perspective view illustrating a first step of a first embodiment of a fiber arraying process that uses the fiber array jig shown in  FIG. 13 .  
       FIG. 18  is a perspective view illustrating a second step of a first embodiment of a fiber arraying process that uses the fiber array jig shown in  FIG. 13 .  
       FIG. 19  is a perspective view illustrating a third step of a first embodiment of a fiber arraying process that uses the fiber array jig shown in  FIG. 13 .  
       FIG. 20  is a perspective view illustrating a temporary fixing step of a first embodiment of a fiber arraying process that uses the fiber array jig shown in  FIG. 13 .  
       FIG. 21  is a perspective view illustrating a fourth step of a first embodiment of a fiber arraying process that uses the fiber array jig shown in  FIG. 13 .  
       FIG. 22  is a side view showing a state in which fibers are arrayed three-dimensionally and tension is applied to each fiber using the fiber array jig shown in  FIG. 13 .  
       FIG. 23  is a perspective view illustrating a first step of a second embodiment of a fiber arraying process that uses the fiber array jig shown in  FIG. 13 .  
       FIG. 24  is a perspective view illustrating a second step of a second embodiment of a fiber arraying process that uses the fiber array jig shown in  FIG. 13 .  
       FIG. 25  is a perspective view illustrating a third step of a second embodiment of a fiber arraying process that uses the fiber array jig shown in  FIG. 13 .  
       FIG. 26  is a perspective view illustrating a fourth step of a second embodiment of a fiber arraying process that uses the fiber array jig shown in  FIG. 13 .  
       FIG. 27  is a perspective view illustrating a temporary fixing step of a second embodiment of a fiber arraying process that uses the fiber array jig shown in  FIG. 13 .  
       FIG. 28  is a perspective view illustrating a fifth step of a second embodiment of a fiber arraying process that uses the fiber array jig shown in  FIG. 13 .  
       FIG. 29A  is a plan view and  FIG. 29B  is a side view of a winding mechanism that can be used in the second step of the aforementioned second embodiment.  
       FIG. 30  is a side view illustrating a fiber fixing step in the present invention.  
       FIG. 31  is a perspective view showing an example of a potting block used in the fiber fixing step.  
       FIG. 32  is a side view illustrating a fiber fixing step in the present invention.  
       FIG. 33  is a side view illustrating a fiber fixing step in the present invention.  
       FIG. 34  is a perspective view showing another example of a fiber array body of the present invention.  
       FIG. 35  is a side view showing yet another example of a fiber array body of the present invention.  
       FIG. 36  is a perspective view showing an example of an organism related substance fixed microarray manufactured using the present invention.  
       FIG. 37  is a perspective view showing one method of introducing organism related substance into each fiber of a fiber array body. 
    
    
     DETAILED DESCRIPTION OF THE INVENTION  
      The present invention will now be described in detail.  
      [Fiber Array Device] 
       FIG. 1  is a perspective view showing a state in which fibers  1  are arrayed three-dimensionally using a fiber array device  10  of the present invention.  
      This fiber array device  10  is equipped with a fiber winding device  11  on which the fibers  1  are wound, and a fiber supply device  12  that supplies fibers to the fiber winding device  11 . These are mounted on a base  13  so as to form the fiber array device  10 .  
      The fiber supply device  12  of this example is formed by a fiber supply bobbin  14  on which the fibers  1  are wound, a guide roller  15  that sends the fibers  1  forward, and a movable guide  16  (described below in detail). Fibers  1  from the fiber supply bobbin  14  are supplied to the fiber winding device  11  via the guide roller  15  and the movable guide  16 .  
      Here, as is shown in an enlarged view in  FIG. 2 , the movable guide  16  is formed in a nozzle shape into which the fibers  1  are inserted, and is able to move in both a vertical direction (i.e., a Z axial direction) and a horizontal direction (i.e., an X axial direction).  
      Specifically, the symbol  17  in  FIG. 1  indicates an X axial stage whose bottom surface is fixed to the top of the base  13  such that a cross section thereof is formed as a rectangular column and the longitudinal direction thereof is aligned in a horizontal direction. An X axial movement table  17   a  is provided on a top surface of this stage and moves in a horizontal direction along this surface. The symbol  18  in  FIG. 1  indicates a Z axial stage, one side surface of which is fixed to the X axial movement table  17   a  such that, in the same manner, a cross section thereof is formed as a rectangular column and the longitudinal direction thereof is aligned in a vertical direction. A Z axial movement table  18   a  is provided on a side surface that forms a right angle with a side surface of this stage and moves in a vertical direction along this surface. The movable guide  16  is able to move freely in a vertical direction and horizontal direction in conjunction with the Z axial movement table  18   a  as it is fixed to the Z axial movement table  18   a . As a result of this movement, the fibers  1  are able to be supplied to the fiber winding device  11 .  
      Note that the horizontal direction in which the movable guide  16  is able to move is a direction that is parallel with the shaft  19   a  of the fiber winding bobbin (described below) indicated by the symbol  19 .  
      A control device (not shown) that controls movement of the movable guide  16  is provided on the movable guide  16 . The timings, directions, and distances of movements by the movable guide  16  can be optionally controlled by this control device.  
      For example, it is possible for an operator to input into the control device using an operating keyboard  20  instructions as to how far and in which direction the movable guide  16  is to move each time the fiber winding bobbin  19  makes one rotation. A motor  40  that is provided with a rotation angle detecting mechanism such as a rotary encoder is connected to the fiber winding bobbin  19 , and a signal is sent to the control device each time the fiber winding bobbin  19  rotates. By employing such a structure, the movable guide  16  moves in accordance with commands from the control unit in conjunction with the rotation of the fiber winding bobbin  19 .  
      It is preferable that an inner diameter of the nozzle-shaped movable guide  16  is formed so as to be 10 to 80% and, more preferably, 30 to 50% larger than the outer diameter of the fibers  1 . It is also preferable that the outer diameter of the nozzle-shaped movable guide  16  is formed so as to be 40 to 150% and, more preferably, 70 to 100% larger than the inner diameter thereof. The length of the nozzle-shaped portion may also be 5 to 30 times the outer diameter and, more preferably, 10 to 20 times the outer diameter. It is also preferable that the nozzle-shaped movable guide  16  is formed from stainless steel.  
      The fiber winding device  11  provided in the fiber array device  10  of this example is formed having a fiber winding bobbin  19  that winds the fibers  1  onto its circumference as it rotates around the shaft  19   a , and fiber array flat plates, two or more of which are stacked at each of a plurality of predetermined positions on the circumference of the fiber winding bobbin  19 , and on whose outer surface the fibers  1  are arrayed.  
      As is shown in  FIGS. 3A and 3B , the fiber winding bobbin  19  is formed as a hexagonal column, and is mounted on the base  13  such that the axial direction thereof is a horizontal direction. The fiber winding bobbin  19  rotates around the shaft  19   a.    
      Four supporting columns  21   a  and  21   b  are provided on each of the six side surfaces of the hexagonal columns so as to be perpendicular to the surfaces. The overall fiber winding bobbin  19  accordingly has a total of  24  supporting columns  21   a  and  21   b . In particular, these supporting columns  21   a  and  21   b  are provided in groups of two on each side surface in the vicinity of the boundaries between adjacent side surfaces. The distance between the two is a short distance (i.e., a pitch D 1 ) for one group and a broad distance (i.e., a pitch D 2 ) for the other group. Hereinafter, the supporting columns provided at the pitch D 1  will be referred to as the precise pitch supporting columns  21   a , while the supporting columns provided at the pitch D 2  will be referred to as the broad pitch supporting columns  21   b . In this example, there are six groups each of both the precise pitch supporting columns  21   a  and the broad pitch supporting columns  21   b.    
      The fiber array device  10  of this example is provided with  60  each of the two types of fiber array flat plates  22   a  and  22   b  shown in  FIGS. 4A and 4B  to make a total of 120.  
      Ten concave rows  23   a , each having the same shape and in each of which is arrayed a single fiber  1 , are formed substantially in parallel with each other on one side of the rectangular fiber array flat plates  22   a  (referred to below as the precise pitch flat plates) shown in  FIG. 4A . In the same way as in the precise pitch array plates  22   a , the rectangular fiber array flat plates (referred to below as the broad pitch flat plates)  22   b  shown in  FIG. 4B  have ten concave rows  23   b  formed on one surface thereof substantially in parallel with each other. In this example, the distance between the concave rows (i.e., the pitch), in particular, and the thickness of the flat plates is greater in the broad pitch flat plates  22   b  compared to the precise pitch flat plates  22   a.    
      Moreover, in this example, the length (i.e., a direction following the concave rows) is longer and the width is smaller in the precise pitch flat plates  22   a  than in the broad pitch flat plates  22   b . Furthermore, when a cross-sectional configuration in the vertical direction of the concave rows  23   a  relative to the lengthwise direction of the concave rows  23   a  is rectangular, it is preferable that the width and depth of the concave rows  23   a  of the precise pitch flat plates  22   a  are within a range of 100 to 125% of the size of the outer diameter of the arrayed fibers. Furthermore, in order to make it easier to accurately array fibers and from the viewpoint of work efficiency when inserting fibers in the concave rows  23   a , it is more preferable that the width and depth of the concave rows  23   a  is approximately 110% of the size of the outer diameter of the fibers  1 . On the other hand, it is preferable that the width and depth of the concave rows  23   b  of the broad pitch flat plates  22   b  is within a range of 105 to 150% of the size of the outer diameter of the fibers  1 . It is possible to array the fibers  1  more accurately in the precise pitch flat plates  22   a.    
      The precise pitch flat plates  22   a  of this example are rectangular flat plates having a thickness of 0.42 mm, a width of 10 mm, and a length of 40 mm. Ten concave rows  23   a  having a width of 0.3 mm and a depth of 0.3 mm are formed at a pitch of (i.e., at intervals of) 0.42 mm along the longitudinal direction on one surface of the rectangular flat plates  22   a . Moreover, the broad pitch flat plates  22   b  of this example are rectangular flat plates having a thickness of 4.5 mm, a width of 8 mm, and a length of 170 mm. Ten concave rows  23   b  having a width of 0.5 mm and a depth of 2 mm are formed at a pitch of 4.5 mm along the longitudinal direction on one surface of the rectangular flat plates  22   b.    
      One circular through hole (indicated by the symbols  24   a  and  24   b ) that is used for positioning is formed in the vicinity of both side ends of the fiber array flat plates  22   a  and  22   b . A pitch D 3  between two positioning through holes  24   a  in the precise pitch flat plates  22   a  is the same as a pitch D 1  between the precise pitch supporting columns  21   a . In addition, a pitch D 4  between two positioning through holes  24   b  in the broad pitch flat plates  22   b  is the same as a pitch D 2  between the broad pitch supporting columns  21   b . Furthermore, the outer diameters of the respective supporting columns  21   a  and  21   b  are formed smaller than the inner diameters of the respective positioning through holes  24   a  and  24   b  so as to provide clearance between them.  
      Accordingly, by fitting the precise pitch supporting columns  21   a  together with the positioning through holes  24   a  of the precise pitch flat plates  22   a , and by fitting the broad pitch supporting columns  21   b  together with the positioning through holes  24   b  of the broad pitch flat plates  22   b , as is shown in  FIG. 5 , the fiber array flat plates  22   a  and  22   b  can each be accurately located at a plurality of predetermined positions on the circumference of the fiber winding bobbin  19 . Furthermore, other fiber array flat plates  22   a  and  22   b  can each be stacked onto the respective fiber array flat plates  22   a  and  22   b  that have already been placed in position. Fibers  1  are arrayed at a narrow array pitch on a stacked body  25  made up of precise pitch flat plates  22   a  that have been stacked in this manner (described below in detail). Fibers  1  are also arrayed on a stacked body  26 , which is formed by stacking broad pitch flat plates  22   b , at a larger array pitch than that of the stacked body  25  formed by stacking the precise pitch flat plates  22   a.    
      Note that if these fiber array flat plates  22   a  and  22   b  are positioned and stacked on the circumference of the fiber winding bobbin  19 , the surfaces thereof on which the concave rows  23   a  and  23   b  are formed become external surfaces.  
      Moreover, in this example, ten layers of the 60 precise pitch flat plates  22   a  are stacked on each of the six groups of precise pitch supporting columns  21  a, while ten layers of the 60 broad pitch flat plates  22   b  are stacked on each of the six groups of broad pitch supporting columns  21   b . In addition, because ten concave rows  23   a  and ten concave rows  23   b  are formed on the respective fiber array flat plates  22   a  and  22   b , by using the fiber array device  10  of this example, it is possible to ultimately stack ten rows multiplied by ten layers of the fibers  1 .  
      Note that, in  FIG. 5 , the precise pitch flat plates  23   a  are stacked onto the precise pitch supporting columns  21  a after a spacer  31  having the same shape as the precise pitch flat plates  22   a  and on which no concave rows  23   a  are formed has first been fitted onto the precise pitch supporting columns  21   a.    
      There is no particular restriction regarding the materials or manufacturing methods of the fiber array flat plates  22   a  and  22   b  provided that the concave rows  23   a  and  23   b  are formed thereon at accurate sizes. For example, preferably, the precise pitch flat plates  22   a  are made by photo etching concave rows on a stainless steel flat plate as this provides both anti-corrosiveness and strength. Alternatively, the precise pitch flat plates  22   a  may preferably be made by molding a resin such as polymethyl methacrylate using a precision injection molding method that employs precise metal dies. For the broad pitch flat plates  22   b , the same materials and manufacturing methods as for the precise pitch flat plates  22   a  can be preferably used. However, in addition to these, it is also possible to use flat plates in which concave rows  23   a  and  23   b  have been formed by machine working stainless steel or aluminum flat plates.  
      The cross-sectional configuration of the concave rows  23   a  and  23   b  that are formed is not limited to a rectangular configuration such as that shown in the drawings. Bottom portions of these concave rows may also be formed having a curved surface shape to follow the external contour of the fibers  1  (i.e., in a U shape), or in a trapezoidal shape or V shape.  
      Moreover, the fiber array device  10  in the example shown in  FIG. 1  is provided with the fiber winding device  11  and the fiber supply device  12  described above. This fiber array device  10  is also provided with a tension imparting device  27  that imparts tension to the fibers  1  supplied to the fiber supply device  12 .  
      The tension imparting device  27  of this example is provided with a torque motor  28  that is connected to the fiber supply bobbin  14 , and with a tensioner  29  that is located on the downstream side of the guide roller  15 . When the fiber  1  is being supplied while the movable guide  16  is moving, as is described above, the tension imparting device  27  is able to impart constant tension within a fixed range to the fiber  1  such that the fiber  1  is not excessively tensioned and is not too loose.  
      As is described above, according to the fiber array device  10  of this example, it is possible to accurately array the fibers  1  in ten rows multiplied by ten layers. Moreover, the fibers  1  are arrayed at a small array pitch in the stacked body  25  of the precise pitch flat plates  22   a . Furthermore, the fibers  1  are arrayed at a larger array pitch in the stacked body  26  of the broad pitch flat plates  22   b  than that in the stacked body  25  of the precise pitch flat plates  22   a . Accordingly, by using this fiber array device  10 , as is described below in detail, it is possible to obtain two fiber array bodies with the fibers arrayed on one end side at a precise array pitch and arrayed on the other end side at an array pitch that is larger than this precise array pitch.  
      Moreover, in this example, there are ten concave rows  23   a  and  23   b  formed in each of the fiber array flat plates  22   a  and  22   b . By stacking these fiber array flat plates  22   a  and  22   b  in ten layers, fibers can be arrayed in ten rows multiplied by ten layers. The number of concave rows  23   a  and  23   b  formed in one fiber array flat plate  22   a  or  22   b  as well as the number of stacked layers are not restricted provided that there is a plurality of each, and can be set to a desired number. Preferably, the number of concave rows  23   a  and  23   b  that are formed in each fiber array flat plate  22   a  and  22   b  is in a range of 5 to 100, while the number of stacked layers of the fiber array flat plates  22   a  and  22   b  is also in a range of 5 to 100.  
      It is also possible to change the number of fibers  1  that are arrayed in each layer by varying the number of concave rows  23   a  and  23   b  that are formed in the fiber array flat plates  22   a  and  22   b  of the respective layers.  
      In this example, the pitch between positioning through holes  24   a  in the precise pitch flat plates  22   a  is taken as D 3 , and the pitch between positioning through holes  24   b  in the broad pitch flat plates  22   b  is taken as D 4 , and D 3  is made equal to D 4 . In this case, it is also necessary for the pitches D 1  and D 2  between the corresponding supporting columns  21   a  and  21   b  to be made equal.  
      Furthermore, in this example, the fiber winding bobbin  19  is a hexagonal column, however, the fiber winding bobbin  19  is not restricted to being a hexagonal column provided that it is able to wind on fiber  1  by rotating around the shaft  19   a . For example, the fiber winding bobbin  19  may be an angular column having between 3 and 5 or also 7 or more side surfaces, or it may not even be an angular column. However, an angular column having between 4 and 8 side surfaces, in particular, is preferably used as this enables fiber  1  to be arrayed with the fiber array flat plates  22   a  and  22   b  placed and stacked stably on the circumference of the fiber winding bobbin  19 .  
      The fiber array flat plates  22   a  and  22   b  that are provided in the fiber array device  10  of this example are favorably used as jigs for accurately arraying fibers  1  in predetermined positions. However, it is not essential for the concave rows  23   a  and  23   b  to be formed therein. For example, it is also possible to employ a structure in which a sticky layer or adhesive layer is formed on the surface of these fiber array flat plates that forms the outer surface thereof when they are stacked on the circumference of the fiber winding bobbin  19 , and for the fibers  1  to be fixed thereto. Examples of methods of forming a sticky layer or adhesive layer include coating a sticky agent or adhesive agent onto the surface that forms the outer surface of the flat plates, and adhering a commercially available two-sided tape onto the surface that forms the outer surface of the flat plates. A material that does not impregnate the fibers  1  is used for the sticky agent, the adhesive agent, or the two-sided tape. If a material that does impregnate the fibers  1  is used, there is a possibility that the fibers  1  will break during the process to array the fibers  1 . A water-soluble vinyl acetate based adhesive agent is preferably used for the adhesive agent.  
      [Fiber Array Method and Fiber Array Object] 
      Next, a description will be given of a specific method for arraying the fibers  1  in ten rows multiplied by ten layers using the fiber array device  10  of the illustrated example.  
      Firstly, a first step is performed in which the positioning through holes  24   a  and  24   b  of the broad pitch flat plates  22   b  and the precise pitch flat plates  22   a  are fitted onto all of the broad pitch supporting columns  21   b  and precise pitch supporting columns  21   a  of the fiber winding bobbin  19 , so that one of each of these flat plates is positioned. At this point, six plates each of the broad pitch flat plates  22   b  and the precise pitch flat plates  22   a  making a total of twelve plates are placed on the circumference of the fiber winding bobbin  19 . Note that, if necessary, a spacer  31  can be placed on the precise pitch supporting columns  21   a  prior to the placement thereon of the precise pitch flat plates  22   a.    
      Next, a second step is performed in which this fiber winding bobbin  19  is rotated a predetermined number of times, and the movable guide  16  is moved by the control device so that the fiber  1  is arrayed on the fiber array flat plates  22   a  and  22   b  that have been put in position.  
      Namely, firstly, by rotating the fiber winding bobbin  19  once, the fiber  1  supplied from the movable guide  16  is inserted in sequence in the concave rows  23   a  and  23   b  on one end of the respective fiber array flat plates  22   a  and  22   b  that have been put in position in the first step. Here, because the concave rows  23   b  at one end of the broad pitch flat plates  22   b  and the concave rows  23   a  and  23   b  at one end of the precise pitch flat plates  22   a  are not on the same circumference, the fiber  1  is supplied while the movable guide  16  is moved appropriately in the X axial direction.  
      After the fiber winding bobbin  19  has been rotated once in this manner, in order to insert the fiber  1  onto the adjoining concave rows  23   a  and  23   b , the movable guide  16  is moved in the X axial direction and the fiber winding bobbin  19  is immediately rotated.  
      Ten concave rows  23   a  or  23   b  are formed in each one of the fiber array flat plates  22   a  and  22   b  of this example. Accordingly, by rotating the fiber winding bobbin  19  ten times, the fiber  1  can be arrayed in sequence as far as the concave rows  23   a  and  23   b  at the other end of the fiber array flat plates  22   a  and  22   b.    
      Note that, it is preferable that tension of 1 to 20 mN, and more preferably, of 5 to 10 mN is imparted by the tension imparting device  27  to the fibers  1  that are arrayed in this manner.  
      It is also preferable that the distance between the distal end of the movable guide  16  and the fiber winding bobbin  19  is as short as possible, as this enables an accurate array to be achieved. It is more preferable that the minimum distance (i.e., the clearance) between the distal end of the movable guide  16  and the concave rows  23   a  and  23   b  of the fiber array flat plates  22   a  and  22   b  where the fibers  1  from the movable guide  16  are arrayed is within a constant range of 0.1 to 2 mm.  
      After the second step has ended in this manner, a third step is performed in which the other fiber array flat plates  22   a  and  22   b  are stacked one by one on top of the fiber array flat plates  22   a  and  22   b  on which the fibers  1  have already been arrayed.  
      Namely, in the same way as in the first step, the positioning through holes  24   a  and  24   b  of the broad pitch flat plates  22   b  and the precise pitch flat plates  22   a  are fitted onto all of the broad pitch supporting columns  21   b  and precise pitch supporting columns  21   a  of the fiber winding bobbin  19 , so that one each of the fiber array flat plates  22   a  and  22   b  is stacked onto each group of supporting columns  21   a  and  21   b . At this point, a total of  24  of the fiber array flat plates  22   a  and  22   b  are placed on the circumference of the fiber winding bobbin  19 .  
      Once the third step has ended in this manner, once again the second step is performed in which the fiber winding bobbin  19  is rotated and the movable guide  16  is moved additionally in the Z axial direction (i.e., upwards). The fibers  1  are then arrayed in sequence in the concave rows  23   a  and  23   b  of the newly positioned fiber array flat plates  22   a  and  22   b . The third step is then again performed.  
      By repeating the above described second step and third step a predetermined number of times and ultimately stacking the fiber array flat plates  22   a  and  22   b  ten times on each group of supporting columns  21   a  and  21   b  so that the fibers  1  are arrayed in all of the concave rows  23   a  and  23   b  of the tenth layer of fiber array flat plates  22   a  and  22   b , it is possible to array fibers in ten rows by ten layers. After fibers have been arrayed in the fiber array flat plates  22   a  and  22   b  of the tenth layer, fiber array flat plates  22   a  and  22   b  may be further mounted and stacked on the top thereof such that the fibers  1  do not become disengaged from the concave rows. Instead of mounting these fiber array flat plates  22   a  and  22   b , it is also possible to mount holding plates that have an identical size and shape to the fiber array flat plates  22   a  and  22 B apart from having no concave rows  23   a  and  23   b  formed therein.  
      By arraying fibers in ten rows by ten layers in this manner, a fiber wound object  30  can be obtained. In particular, the fiber wound object  30  of this example has six stacked objects  25  formed by the precise pitch flat plates  22   a  and six stacked objects  26  formed by the broad pitch flat plates  22   b . In these, the array pitches of the fibers  1  that are arrayed in the fiber array flat plates  22   a  and  22   b . are different. Accordingly, the fibers  1  are arrayed at two different array pitches in a single fiber wound object  30 .  
      [Method of Manufacturing A Fiber Array Body] 
      Next, a description will be given of a method of manufacturing two fiber arrayed bodies  32 , such as that shown in  FIG. 7 , from the fiber wound object  30  shown in  FIG. 6  that has been obtained using the above described method.  
      In this fiber array body  32 , a portion of the fibers  2 , which have been arrayed in ten rows by ten layers, that is arrayed on the precise pitch flat plates  22   a  (i.e., a portion  25 ′ positioned between stacked objects  25  that are made up of the precise pitch flat plates  22   a ) is fixed in a block shape by a curable resin  33  with its array pattern being maintained. In contrast, the array pattern of the portion that is arrayed on the broad pitch flat plates  22   b  is maintained by the stacked objects  26  that are made up of the broad pitch flat plates  22   b . Briefly (a more detailed explanation is given below), the portion of this fiber array body  32  that is fixed by the curable resin  33  is sliced in a direction that intersects the fibers  2 , and, preferably, in a direction that is substantially perpendicular to the fibers  2  so as to form thin pieces. As a result, an organism related substance fixed microarray  35  such as that shown in  FIG. 8  is obtained. Note that, in  FIG. 7 , the symbol  34  indicates a frame member. The stacked object  26  that is made up of the broad pitch flat plates  22   b  is fitted into this frame member  24  so that it does not fall apart.  
      One method of manufacturing this type of fiber array body  32  from the fiber wound object  30  shown in  FIG. 6  is a method that uses a potting block to surround the ten rows by ten layers of the fibers  1  that are suspended between the stacked objects  25  that are made up of the precise pitch flat plates  22   a.    
      Preferably, the potting block that is used is formed in a cylindrical shape by combining together in the manner shown in  FIG. 9  four plate-shaped block pieces  36   a ,  36   b ,  36   c , and  36   d  that are made, for example, from a metal such as aluminum. Moreover, when these four pieces are combined together in a cylinder shape, it is preferable that mold release processing is performed by fixing a sheet-shaped material  37  that is formed from highly non-adhesive Teflon (registered trademark), polyethylene, polypropylene or the like on the surfaces of these four pieces that will form inner wall surfaces and on surfaces thereof where the block pieces will be in contact with each other. If this type of mold release processing is performed, then after a hollow portion  36   e  of the potting block  36  is subsequently filled with a curable resin solution which is then cured, the potting block  36  can be easily separated from the cured resin. Instead of performing this mold release processing on the block pieces  36   a ,  36   b ,  36   c , and  36   d , which are made of metal, it is also possible to form the potting block itself from a highly non-adhesive resin.  
      A semi-conical notch  38  that, in this example, becomes wider towards one end thereof is preferably formed in one surface of the inner wall surfaces of the cylindrical potting block  36 . As is described below, this notch  38  then forms a filling aperture when the hollow portion  36   e  of the potting block  36  is later filled with a curable resin solution.  
      As is shown in  FIG. 10 , this potting block  36  is fixed so as to enclose the fibers  1  between the stacked objects  25  that are formed by the precise pitch flat plates  22   a , and so that the one end of the potting block  36  where the filling aperture is not formed is in close contact with one of the stacked objects  25  of precise pitch flat plates  22   a . At this time, a sealing member formed from silicon rubber or the like that has peelability and elasticity is interposed so that the curable resin solution that is supplied later does not leak out from the close contact portion between the potting block  36  and the stacked object  25 .  
      After this, the end of the potting block  36  on the side where the filling aperture is formed (i.e., the aperture end) is positioned facing upward, and curable resin solution is poured into the hollow portion  36   e  of the potting block  36  through the filling aperture that is formed in the potting block  36 . Subsequently, the potting block  36  is left undisturbed at a predetermined temperature for a predetermined length of time so that the supplied curable resin solution is able to harden.  
      Note that when filling the hollow portion  36   e  with the curable resin solution, it is preferable that the curable resin solution is stirred and degassed in advance in a vacuum. If it is degassed, there are no air gaps inside the resin after it has cured and the resin sufficiently permeates the space between the fibers  1 . It is even more preferable if the curable resin solution is sufficiently degassed and if the above described resin filling task is conducted under reduced pressure.  
      After the curable resin solution with which the interior of the potting block  36  has been filled has cured, the potting block  36  is disassembled into the four block pieces  36   a ,  36   b ,  36   c , and  36   d . As a result, the fibers that have been arrayed precisely in ten rows by ten layers are fixed by resin in a block shape.  
      Moreover, in the same way as in the method described above, the fibers  1  between the stacked objects  25  formed by other precise pitch flat plates  22   a  in this fiber wound object  30  are also fixed using the curable resin  33  so that the state shown in  FIG. 11  is obtained.  
      Thereafter, the fibers  1  arrayed in ten rows by ten layers in this fiber arrayed object  30  are appropriately cut open, and all of the precise pitch flat plates  22   a  are removed. Furthermore, by removing all of the broad pitch flat plates  22   b  other than the two stacked objects indicated by the symbols  26   a  in  FIG. 11 , two fiber arrayed bodies  32  in the state shown in  FIG. 7  can be obtained.  
      Note that the type of curable resin  33  that is used here is preferably a curable resin solution that is in a low viscosity state at normal temperature and that is able to fill the hollow portion  36   e  of the potting block  36  and then cure at room temperature, and that after curing is able to be sliced easily by a cutter or the like into thin pieces having a uniform thickness. Furthermore, the obtained thin pieces should preferably have sufficient hardness and elasticity that they do not become chipped or broken. Examples of this type of curable resin  33  include two-liquid reaction curable resins such as urethane resins.  
      [Fiber] 
      There is no particular restriction as to the type of fiber  1  that is arrayed and then fixed in the manner described above. Examples thereof include chemical fibers such as synthetic fibers, semisynthetic fibers, regenerated fibers, and inorganic fibers as well as natural fibers and composite fibers of these.  
      Representative examples of synthetic fibers include: various types of polyamide based fibers such as nylon 6, nylon 66, and aromatic polyamides; various types of polyester based fibers such as polyethylene terephthalate, polybutylene terephthalate, polylactic acids, and polyglycolic acids; various types of acrylic based fibers such as polyacrylonitrile; various types of polyolefin based fibers such as polyethylene and polypropylene; various types of polyvinyl alcohol based fibers; various types of polyvinylidene chloride based fibers; various types of polyvinyl chloride based fibers and polyurethane based fibers; phenol based fibers; fluorine based fibers such as polyvinylidene fluoride and polytetrafluoroethylene; polyalkylene paraoxybenzoate based fibers; fibers that use (meth)acrylic based resins such as polymethyl methacrylate; and fibers that use polycarbonate based resins.  
      Representative examples of semisynthetic fibers include: various types of fibers that are based on cellulose based derivatives that use diacetate, triacetate, chitin, or chitosan as a raw material; and various types of protein based fibers that are known as promix.  
      Representative examples of regenerated fibers include various types of cellulose based regenerated fibers such as rayon, cupra, and polynosic that are obtained using a viscose method, a copper-ammonia method, or an organic solvent method.  
      Representative example of inorganic fibers include glass fibers, and carbon fibers.  
      Representative examples of natural fibers include: vegetable fibers such as cotton, flax, ramie, and jute; animal fibers such as wool and silk; and mineral fibers such as asbestos.  
      These fibers  1  can be used as is appropriate in the manufacturing of the fiber arrayed bodies  32 , however, as is described above, because tension is imparted to the fibers  1  when the fibers  1  are being arrayed, of the above described fibers polycarbonate based fibers, polyester based fibers, nylon based fibers, and aromatic polyamide fibers and the like that have a high modulus of elasticity and yield strength are preferably used.  
      Any fibers other than natural fibers that are obtained from a known fiber forming technology such as a melt spinning method, a wet spinning method, and a dry spinning method, or from a combination of these technologies can also be used.  
      Furthermore, unprocessed fibers may be used without any modification thereto for the fibers  1 , however, if necessary, fibers into which a reactive functional group has been introduced may be used, or fibers that have undergone plasma processing or irradiation processing using γ-rays or electron beams or the like may be used.  
      Moreover, there is no particular restriction as to the form of the fibers  1 , and they may be in monofilament form or in multifilament form. In addition, the fibers  1  may be formed by spun yarn obtained by spinning short fibers. The fibers  1  may also be hollow fibers or fibers having a porous structure. Hollow fibers can be manufactured using a known method that employs special nozzles.  
      There is no particular restriction as to the outer diameter of the fibers  1  and fibers  1  having the desired outer diameter can be used. However, if the outer diameter is too small, breakages tend to occur and there is a deterioration in the ease of handling. On the other hand, the smaller the outer diameter of the fibers  1 , the higher the density at which the fibers  1  are able to be arrayed. Accordingly, the outer diameter of the fibers  1  is set so as to provide both ease of handling and the desired arrayed density. Preferably, the outer diameter of the fibers  1  is 500 μm or less, and more preferably 300 to 100 μm. If a multifilament fiber is used for the fibers  1 , then 83 dtex/36 filament or 82 dtex/45 filament or the like can be used without any modification.  
      For example, a monofilament fiber having an outer diameter of 150 μm is used for the fibers  1  when the organism related substance fixed microarray  35  is being manufactured from the fiber array body  32 . When this monofilament fiber is arrayed at an array pitch of 200 μm, the number of fibers  1  that can be arrayed inside a 1 cm 2  square is 2400. Accordingly, by fixing one type of organism related substance in one single fiber, it is possible to fix 2400 types of organism related substance in each square centimeter. Moreover, if monofilament porous fibers, monofilament hollow fibers or monofilament porous hollow fibers having an outer diameter of approximately 200 μm are arrayed at an array pitch of 200 μm, a fiber array body  32  in which approximately 1000 fibers  1  are arrayed in each square centimeter can be obtained. Accordingly, by fixing one type of organism related substance in one single fiber, it is possible to fix 1000 types of organism related substance in each square centimeter.  
      [Method of Manufacturing an Organism Related substance Fixed Microarray] 
      Next, a description will be given of a method of manufacturing the organism related substance fixed microarray  35  from a fiber array body  32  obtained in the manner described above.  
      Here, if fibers  1  are used in which an organism related substance has previously been fixed, then by slicing this fiber array body  32  into thin pieces in a direction intersecting the fibers  1 , as is shown in  FIG. 8 , the fibers  1  in which organism related substance has been fixed are fixed by the curable resin  33 , and thin slices of the organism related substance fixed microarray  35  can be obtained on both surfaces of which is exposed a cross-section of the fibers  1 . The device used for slicing can be appropriately selected, and a microtome, laser, or the like can be used. The direction of the slices should be a direction that intersects the longitudinal direction of the fibers  1 . Preferably, it should be a direction that is perpendicular to the longitudinal direction of the fibers  1 .  
      If the organism related substance fixed in the fibers  1  is, for example, a nucleic acid, then by providing a specimen for the obtained organism related substance fixed microarray  100  and performing hybridization, it is possible to detect a specific nucleic acid array present in the specimen using the nucleic acid fixed to the fibers as a probe.  
      Note that if a multifilament fiber or spun yarn or the like is used for the fibers  1 , then it is possible to fix organism related substance in the gaps between the fiber units. Moreover, if a hollow or porous fiber is used for the fibers  1 , then it is possible to fix organism related substance in the hollow portions or in the gaps within the fibers  1 .  
      If, on the other hand, a porous fiber, a hollow fiber, or porous hollow fiber in which no organism related substance has been fixed is used for the fibers  1 , then organism related substance can be fixed thereto using the method described below. 
      (1) A well plate  39  (see  FIG. 12 ) is prepared having a liquid that contains organism related substance placed inside each block. One end portion of each of the fibers  1  on the side thereof where the array state is maintained by a frame member  34  and by a stacked body  26  made up of broad pitch flat plates  22   b  of the fiber array body  32  shown in  FIG. 7  is inserted into each block.     (2) Next, by placing the other end of the fibers  1  in a reduced pressure state so as to suction the liquid, the liquid that contained the organism related substance is suctioned up into the hollow portions and porous portions of each of the fibers  1 , and the organism related substance is introduced inside each of the fibers.    

      A commercially available well plate can be used for the well plate  39 . At this time, if the array pitch of the fibers  1  in the broad pitch flat plates  22   b  has previously been made the same as the pitch of each block in the well plate  39 , then it is possible to insert the end portion of each single fiber easily into each block.  
      Note that the type of organism related substance that is introduced into each fiber  1  may be different in every single one of the ten rows by ten layers of fibers  1 . It is also possible to group together a plurality of fibers and introduce the same type of organism related substance into that group. If the types of organism related substance are all different from each other, it is possible to obtain an organism related substance fixed chip  35  in which 100 types of organism related substance has been fixed.  
      Examples of the organism related substance that is introduced into the fibers  1  in this manner include nucleic acids such as deoxyribonucleic acid (DNA), ribonucleic acid (RNA), peptide nucleic acid (PNA), and oxypeptide nucleic acid (OPNA) as well as proteins and polysaccharides.  
      If a nucleic acid is used as the organism related substance, the DNA or RNA from living cells may be prepared using a known method. For example, DNA may be extracted using Blin&#39;s method (see Blin et. Al., Nucleic Acids Res. 3: 2303 (1976)). RNA may be extracted using Favaloro&#39;s method (see Favaloro et. Al., Methods Enzymol. 65: 718 (1980)).  
      It is also possible to use chain or toroidal plasmid DNA or chromosome DNA, DNA pieces obtained by slicing these using restriction enzymes or by chemically slicing them, DNA that has been synthesized by enzymes in a test tube, or else chemically synthesized DNA. For example, DNA may be extracted using Blin&#39;s method (see Blin et. Al., Nucleic Acids Res. 3: 2303 (1976)). RNA may be extracted using Favaloro&#39;s method (see Favaloro et. Al., Methods Enzymol. 65: 718 (1980)).  
      These various organism related substance types may be used unmodified as they are, or they may be used in the form of derivatives in which the organism related substance has undergone chemical modification, or, if necessary, they may transformed and then used. For example, if a nucleic acid is used for the organism related substance, then amino formation, biotin formation, digoxigenin formation and the like, which are known as methods for chemically modifying organism related substance (Current Protocols in Molecular Biology, Ed.; Frederick M. Ausubel et. al. (1990) and Deisotoping Experimental Protocols (1) DIG Hybridization (shuujunsha)), can be employed.  
      As the solution that contains these types of organism related substance, for example, an acrylamide aqueous solution that contains organism related substance into which an unsaturated functional group has been introduced is used. After this solution has been suctioned into the hollow portion or porous portion or the like of the fibers, as is described above, it is heated to 50 to 60° C. As a result, a gel in which the organism related substance has been fixed to the gel network can be fixed to the hollow portion or porous portion.  
      As is described above, when fibers  1  are being arrayed three-dimensionally, the fiber array device  10  that is used is equipped with a fiber winding device  11  on which fiber is wound and a fiber supply device  12  that supplies the fibers  1  to the fiber winding device  11 . The fiber supply device  12  is provided with a movable guide  16  that supplies fiber while moving relatively to the fiber winding device  11 . The fiber winding device  11  has a fiber winding bobbin  19  that rotates around a shaft  19   a  while the fibers  1  are wound onto the circumference thereof, and fiber array flat plates  22   a  and  22   b , a plurality of which are stacked respectively at a plurality of predetermined positions on the circumference of the fiber winding bulb in  19 , and on whose respective external surfaces the fibers  1  are arrayed. As a result, the fibers  1  can be arrayed at a high density, with a high degree of accuracy, in a short time, and extremely efficiently, and it also becomes possible to mass produce the fiber array bodies  32  for industry. Namely, if this type of fiber array device  10  is used, it is not necessary to perform the complex task of inserting individual fibers through holes formed in a jig, as is the case conventionally. Moreover, because it is not necessary to guide the fibers being inserted into the holes using forceps or the like, the problem of fibers that have already being inserted into adjacent holes obstructing the operation when inserting fibers using forceps does not arise. In addition, because the operation is not one of inserting the fibers  1  into holes, but of arraying them in the concave rows  21 , even if the outer diameter of the fibers is narrow and they have low rigidity, they can be arrayed easily so that a greater degree of density in the array of the fibers  1  becomes possible.  
      Namely, by using the fiber array device  10  that is described above, even if the outer diameter of the fibers  1  is small and they are difficult to handle, they can still be arrayed accurately at a high density and also efficiently in a short time, and mass production of the fiber arrayed bodies  32  becomes possible. As a result, it is also possible to mass produce organism related substance fixed microarrays  35  that enable a large variety of samples to be analyzed.  
      Moreover, in particular, the fiber array flat plates  22   a  and  22   b  have a plurality of concave rows  23   a  and  23   b , in each one of which is arrayed a single fiber  1 , formed substantially parallel to each other in an external surface thereof, and the fiber array flat plates  22   a  and  22   b  are stacked on the circumference of the fiber winding bobbin  19  so that the concave rows  23   a  and  23   b  are perpendicular to the shaft  19   a  of the fiber winding bobbin  19 . As result, the fibers  1  can be arrayed more accurately and reliably.  
      Furthermore, by using the precise pitch flat plates  22   a  and the broad pitch flat plates  22   b  as the fiber array flat plates  22   a  and  22   b , it is possible to easily obtain a fiber array body  32  at one end of which the fibers are arrayed at a precise array pitch, and at the other end of which the fibers are arrayed at an array pitch that is broader than this precise array pitch. If this type of fiber array body  32  is used, then, as is described above, it is also possible to easily introduce organism related substance to each fiber  1  using the well plate  39 .  
     EXAMPLES  
      The present invention will now be described specifically using examples.  
     Example 1  
      A fiber array device  10  having the same structure as that shown in  FIG. 1  was used apart from the fact that the broad pitch flat plates  22   b  shown in  FIG. 4B  were completely omitted and  120  of only the precise pitch flat plates  22   a  shown in  FIG. 4A  were provided, and apart from the fact that twelve groups (i.e.,  24  altogether) of only the precise pitch supporting columns  21   a  were erected as fiber winding bobbins. Using this fiber array device  10 , a fiber wound object in which polycarbonate hollow fibers having a diameter of 0.3 mm were arrayed in ten rows by ten layers was obtained.  
      Note that the movement speed in the X axial direction of the nozzle-shaped movable guide  16  was set at 12000 mm/minute, and the movement pitch was set at 0.42 mm, which was the same as the pitch between the concave rows  23   a  in the precise pitch flat plates  22   a . 5 mN of tension was imparted by a tension imparting device to the hollow fibers that were arrayed in this manner. In addition, the minimum distance (i.e., the clearance) between the distal end of the movable guide  16  and the concave rows of the precise pitch flat plates  22   a  where the fibers  1  from the movable guide  16  were arrayed was set at a constant 0.5 mm. The revolution speed of the fiber winding bobbin  19  was set at 10 rpm. The inner diameter, outer diameter, and length of the nozzle-shaped movable guide  16  were set respectively at 0.4 mm, 0.7 mm, and 12 mm.  
      As a result, in approximately one hour of working time, a fiber wound object in which fibers  1  were accurately arrayed in ten rows by ten layers was obtained.  
     Example 2  
      Using the fiber array device  10  shown in  FIG. 1 , a fiber wound object  30  such as that shown in  FIG. 6  in which polycarbonate hollow fibers having a diameter of 0.3 mm were arrayed in ten rows by ten layers was obtained.  
      Note that the movement speed in the X axial direction of the nozzle-shaped movable guide  16  was set at 12000 mm/minute. The movement pitch was set at 0.42 mm for the precise pitch flat plates  22   a , which was the same as the pitch between the concave rows  23   a  in the precise pitch flat plates  22   a , and was set at 4.5 mm for the broad pitch flat plates  22   b , which was the same as the pitch between the concave rows  23   b  in the precise pitch flat plates  22   b . 5 mN of tension was imparted by a tension imparting device to the hollow fibers that were arrayed in this manner. In addition, the minimum distance (i.e., the clearance) between the distal end of the movable guide  16  and the concave rows  23   a  and  23   b  of the fiber array flat plates  22   a  and  22   b  where the fibers from the movable guide  16  were arrayed was set at a constant 0.5 mm. The revolution speed of the fiber winding bobbin  19  was set at 10 rpm.  
      As a result, in approximately one hour of working time, a fiber wound object  30  in which the fibers  1  were arrayed in ten rows by ten layers at two different array pitches in the same fiber arrayed object  30  was obtained.  
     Example 3  
      A potting block  36  such as that shown in  FIG. 9  was placed in two locations on portions sandwiched between two stacked objects  25  of the precise pitch flat plates  22   a  in the fiber wound object  30  obtained in Example 2. As is shown in  FIG. 10 , a polyurethane elastomer (coronate 4403/nippolan 4276 mixed in a proportion of coronate 6: nippolan 4) solution was then poured into the interior of the hollow portion and hardened so that the state shown in  FIG. 11  is obtained. Thereafter, the fibers  1  were cut open and the fiber array flat plates  22   a  and  22   b  were appropriately removed. As a result, two block-shaped fiber arrayed bodies  32  in which the fibers  1  were accurately arrayed in the manner shown in  FIG. 7  were prepared from a single fiber wound object  30 . The required working time was approximately one hour up until the pouring of the resin solution.  
     Example 4  
      A fiber wound object  30  such as that shown in  FIG. 6  was obtained in which the fibers  1  were arrayed in the same manner as in Example 1 except for the fact that the torque motor  28  of the tension imparting device  27  was not operated and for the fact that the above described clearance was 3 mm.  
     Example 5  
      A fiber wound object  30  such as that shown in  FIG. 6  was obtained in which the fibers  1  were arrayed in the same manner as in Example 1 except for the fact that the fibers  1  were supplied without being passed through the tensioner  29  of the tension imparting device  27 .  
     Example 6  
      A fiber wound object  30  such as that shown in  FIG. 6  was obtained in which the fibers  1  were arrayed in the same manner as in Example 1 except for the fact that the clearance was set to 10 mm.  
     Example 7  
      A fiber wound object  30  such as that shown in  FIG. 6  was obtained in which the fibers  1  were arrayed in the same manner as in Example 1 except for the fact that, instead of concave rows, an adhesive layer made up of a vinyl acetate based adhesive agent was formed on the precise pitch flat plates. Thereafter, resin fixing was performed on the fibers  1  in the same way as in the above described Example 3 so that two block-shaped hollow fiber arrayed resin bodies were prepared.  
      According to each of the above described examples, it is possible to array fibers accurately in a short length of time. In particular, according to Examples 1 to 3, a particularly accurate fiber array is possible. Moreover, in Example 3, an excellent fiber array body was obtained in which the fibers remained fixed in this state.  
      In contrast, in Examples 4 and 6, the array state of the fibers was somewhat inferior compared to that of Examples 1 to 3. In Example 5, there was a tendency for considerable stress to be placed on the fibers when the movable guide  16  was being moved.  
     Comparative Example 1  
      For the fiber array jig two stainless steel porous plates having a thickness of 0.1 mm were used in which a total of 49 holes having a diameter of 0.32 mm were prepared at a pitch of 0.42 mm using a photoetching method in seven rows horizontally and seven rows vertically. 49 lengths of polycarbonate hollow thread (having an outer diameter of 0.3 mm×a length of 1 m) were inserted into all of the holes in the porous plates, and a gap of 50 mm was set between the two porous plates.  
      Next, the hollow threads between the two porous plates that were arrayed in this manner were placed inside a potting jig. The same polyurethane elastomer (i.e., coronate 4403/nippolan 4276) as that used in Example 3 was then poured into the space enclosed by the porous plates and the potting jig. As a result, a hollow thread arrayed body was formed in a block shape whose vertical, horizontal, and height dimensions were 20 mm×20 mm×50 mm respectively. The working time was approximately six hours up until the pouring of the resin solution.  
      Next, a detailed description will be given of the fiber array jig of the present invention and of a method of manufacturing a fiber array body using this jig.  
      [Fiber Array Jig] 
      The fiber array jig of the present invention is used in order to array a plurality of fibers three-dimensionally, and a fiber array body is obtained by fixing the three-dimensionally arrayed fibers in this state.  
       FIG. 13  is a perspective view showing an example of a fiber array jig  110 .  
      As is also shown in  FIGS. 14A and 14  B, this fiber array jig  110  has ten fiber array flat plates  120  that are made up of rectangular flat plates, and six concave rows  121 , in each one of which is arrayed a single fiber, are formed substantially parallel with each other in one surface of these fiber array flat plates  120 . The fiber array jig  110  also has a positioning jig  130  for accurately positioning the fiber array flat plates  120  in predetermined positions.  
      As is shown in  FIG. 14A , one circular positioning through hole (indicated by the symbols  122 ) is formed in the vicinity of both ends of each of the fiber array flat plates  120  of this example. In contrast, as is shown in  FIG. 14B , the positioning member  130  is formed by a base  133  in the form of a rectangular flat plate, and two groups (with two columns in each group) of supporting columns  132  (to make a total of four) that stand vertically relative to the base  133 . A spacing D 5  between the two positioning through holes  122  that are formed in each of the fiber array flat plates  120  is formed so as to be the same as a spacing D 6  between each group of the supporting columns  132  that are erected on the base  133 . In addition, the outer diameter of the supporting columns  132  is formed slightly smaller than the inner diameter of the positioning through holes  122  so that a sufficient clearance is provided. As is shown in  FIG. 13 , by inserting the supporting columns  132  into the positioning through holes in the respective fiber array flat plates  120 , each of the fiber array flat plates  120  can be accurately placed in a predetermined position.  
      Namely, in the fiber array jig  110  of this example, as is shown in  FIG. 13 , using the positioning member  130 , two fiber array flat plates  120  can be placed on the base  133  such that the concave rows  121  that are formed in the fiber array flat plates  120  are placed in alignment with each other, and such that a predetermined spacing W is provided between them. Furthermore, by stacking other fiber array flat plates  120  on top of the fiber array flat plates  120  that are already placed on the base  133 , ultimately, two groups can be stacked having five layers of the fiber array flat plates  120  in each group.  
      Accordingly, by arraying one fiber in each of the concave rows  121  of each fiber array flat plate  120  (described below in detail), according to this fiber array jig  110 , fibers can be arrayed in five layers with each layer having six rows.  
      Note that the symbol  131  in the drawings indicates a spacer that is formed by a rectangular plate the same shape as the fiber array flat plates  120 . Two circular positioning through holes are formed in the vicinity of both ends thereof. The spacers  131  are positioned using the positioning members  130  by the same method as that employed for the fiber array flat plates  120 . The spacers  131  can be used if necessary, and spacers  131  having the desired thickness can be used as is appropriate in accordance with the thickness of the potting block that is used in the fiber fixing process (described below in detail).  
      Here, the width and depth of the concave rows  121  formed in the fiber array flat plates  120  can be appropriately set in accordance with the outer diameter of the fibers that are arrayed in the concave rows  121 . When the cross-sectional configuration in the vertical direction of the concave rows  121  relative to the lengthwise direction is rectangular, as is the case in this example, it is preferable that the width and depth are within a range of 100 to 125% of the size of the outer diameter of the arrayed fibers. If the width and depth are this size, then the fibers can be arrayed without protruding from the concave rows  121 . Furthermore, in order to make it easier to accurately array fibers and from the viewpoint of work efficiency when inserting fibers in the concave rows  121 , it is most preferable that the width and depth of the concave rows  121  is approximately 110% of the size of the outer diameter of the fibers. If the concave rows  121  have uniform dimensions and are deep enough for the fibers not to protrude and for the fibers to be easily inserted therein, then the cross-sectional configuration thereof is not limited to the rectangular configuration shown in the examples in the drawings. Bottom portions of the concave rows  121  may also be formed having a curved surface shape to follow the external contour of the fibers (i.e., in a U shape), or in a trapezoidal shape or V shape.  
      The material used to form the fiber array flat plates  120  is not particularly limited, however, a metal is preferable. In particular, a stainless steel based spring steel is preferably used as the metal from the viewpoint of its anti-corrosion properties and its strength.  
      The method used to manufacture the fiber array flat plates  120  only needs to involve preparing a flat, metal plate and then forming concave rows in one surface thereof. Methods that may be used to form the concave rows in the flat, metal plate include: 1) a method in which the concave rows  121  are formed one at a time by machining; 2) a method in which a plurality of concave rows  121  are carved out and formed simultaneously using a special edged tool; 3) and a method in which the concave rows  121  are formed by etching. In addition to these, 4) another method may be used in which flat, metal plates (a) having the same thickness as the depth of the concave rows  121  being formed are prepared, and are then processed in a lattice configuration by etching. The bar portions forming the lattice of the lattice-shaped member that is obtained only are then bonded to another flat, metal plate (b), and by then cutting the bar portions protruding from the flat, metal plate (b), concave rows  121  having the same depth as the thickness of the flat, metal plates (a) being used are formed.  
      Among these methods, on methods 1) and 2), because the concave rows  121  are formed by machining, when forming particularly detailed concave rows  121 , care must be taken that there are no dimensional changes caused by heat from the machining and no bending caused by residual stress from the machining, and also that there are no changes in the width or depth of the concave rows  121  caused by wearing of the cutting edge. In addition, although in the method based on etching there are no problems with dimensional changes or bending such as those that may be recognized in methods 1) and 2), it is still necessary to control the depth of the concave rows  121  by the etching conditions. As a result, it is necessary for the etching conditions to be suitably set or regulated. Accordingly, method 4) is preferable as the method for forming the concave rows  121  because precise concave rows  121  can be formed without the etching conditions needing to be set and regulated as strictly as in method 3).  
      In this method 4), the method used to bond the lattice member to the flat, metal plate (b) may be a bonding method using an adhesive agent, or may be a method in which a thin film of a metal that will become a binder is formed on a bonding surface of the lattice member or flat, metal plate (b), and the two are then bonded together by applying heat and pressure. However, if an adhesive agent or binder is used, there is a possibility of unevenness being generated in the thickness of the concave rows  121  due to unevenness in the thickness of the binder or adhesive agent. There is also a possibility of the concave grooves being narrowed due to excess binder or adhesive agent spreading from the bonding surface into the concave rows  121 , and a possibility of bending occurring that is caused by a bimetal effect generated by any difference in the coefficients of thermal expansion of the materials. Accordingly, in order to obviate these possibilities, it is preferable that the same material is used to form the lattice member and the flat, metal plate (b), and that these are bonded together using solid phase diffusion bonding in which the metal structures are integrated and bonded together by applying heat and pressure to the lattice member and the flat, metal plate (b) in a vacuum.  
      Note that, as is described above, a metal such as a stainless steel based spring steel is preferably used as the material of the fiber array flat plates  120 , however, provided that sufficient strength and dimensional accuracy are ensured, it is also possible to use a thermoplastic synthetic resin, a thermosetting synthetic resin, a photocurable synthetic resin or the like. In this case, a method may be used in which these resins are molded by press molding or injection molding using a precise metal mold so as to form the fiber array flat plates  120 . According to this type of molding method, identical fiber array flat plates  120  can be manufactured in large quantity and at low cost.  
      There is also no particular restriction as to the material of the positioning member  130 , however, it is preferable that stainless steel or the like that has excellent strength and rust resistance is used.  
      Note that, in the fiber array jig  110  shown in  FIG. 13 , as is described above, by fitting the supporting columns  132  of the positioning member  130  together with the positioning through holes  122  of the respective fiber array flat plates  120 , the placement positions of the plurality of fiber array flat plates  120  can be decided specifically and accurately. According to this type of positioning mechanism, positioning can be achieved with a high degree of accuracy using a simple structure. However, there are no restrictions on the positioning mechanism provided that the fiber array flat plates  120  can be positioned specifically and accurately. For example, as is shown in  FIG. 15 , a positioning member that has guide members  135  having a  -shaped horizontal cross section standing on the flat, rectangular plate-shaped base  133  instead of supporting columns can be used as the positioning member  130 . In the positioning member  130  shown in  FIG. 15 , two groups are provided with each group formed by two  -shaped guide members  135  positioned facing each other. The fiber array flat plates  120  are placed or stacked between the guide members  135  of each group. As a result, the placement positions of a plurality of fiber array flat plates  120  can be decided specifically and accurately.  
      Moreover, in the fiber array jig  110  shown in FIGS.  13  to  14 B, six of the concave rows  121  are formed in each fiber array flat plate  120 , and these fiber array flat plates  120  are stacked in five layers. As a result, it is possible to array a total of  30  fibers. The number of concave rows  121  that are formed in each single fiber array flat plate  120  as well as the number of layers of stacked fiber array flat plates  120  is not restricted provided that there are a plurality of each, and can be set to desired numbers. Preferably, the number of concave rows  121  formed in each fiber array flat plate  120  is in a range of 6 to 100, and more preferably in a range of 10 to 100. The number of layers of stacked fiber array flat plates  120  is preferably in a range of 5 to 100, and more preferably in a range of 10 to 100.  
      Moreover, it is also possible to change the number of fibers that are arrayed in each layer by varying the number of concave rows  121  that are formed in each fiber array flat plate  120  of the respective layers.  
      Furthermore, there is no particular restriction as to the spacing W between two fiber array flat plates  120  that are placed such that the concave rows  121  that are formed in each fiber array flat plate  120  are placed in alignment with each other, and this spacing W can be set as is appropriate. Here, if the spacing W is set as a large spacing, then an elongated product can be obtained as the fiber array body that is ultimately obtained. If an elongated product is obtained, then when the fiber array body is sliced into thin pieces in a direction intersecting the fibers and an organism related substance fixed microarray is being manufactured, a large number of organism related substance fixed microarrays can be obtained from a single fiber array body, which is advantageous as regards manufacturing costs. However, the larger the spacing W, the more difficult it becomes to strictly control the array state of the fibers between the two fiber array flat plates  120 . Accordingly, it is preferable that the spacing W is suitably set in consideration of these viewpoints.  
      Furthermore, in the fiber array jig  110  of this example, firstly, two fiber array flat plates  120  are positioned and then the other fiber array flat plates  120  are each stacked on top of these two plates. As a result, two groups of stacked fiber array flat plates  120  are formed. It is also possible for three or more fiber array flat plates  120  to be placed in position and for each of the other fiber array flat plates  120  to be stacked on top of these so that three or more groups of stacked fiber array flat plates  120  are formed provided that the fiber array flat plates  120  are positioned with a predetermined spacing between each such that the concave rows  121  that are formed in each fiber array flat plate  120  are in alignment with each other. For example, if N number of groups of stacked fiber array flat plate  120  are being formed, the fiber array objects can be manufactured as N-1 groups, and it is necessary for the two supporting columns  132  for each group that are provided on the positioning member  130  to be two supporting columns  132  for N groups.  
      [Method of Manufacturing a Fiber Array Body] 
      Next, a description will be given of a method of manufacturing a fiber array body  150  (see  FIG. 16 ) in which 30 fibers are fixed while being arrayed three-dimensionally. This fiber array body  150  is obtained by performing a fiber array step in which 30 fibers are arrayed three-dimensionally using the fiber array jig  110  shown in  FIG. 13 , and by then performing a fiber fixing step in which these fibers are fixed while being in a three-dimensionally arrayed state. In the fiber array body  150  shown in  FIG. 16 , 30 fibers  140  are inserted substantially in parallel with each other in the direction shown by the arrows.  
      The symbol  151  indicates a curable resin, and the 30 fibers are fixed with the spacing between each maintained by this resin.  
      (Fiber Array Step)  
      Two specific embodiments can be preferably illustrated for the fiber array step. Firstly, a first embodiment will be described.  
      In the first embodiment, firstly, as is shown in  FIG. 17 , the positioning through holes of the respective spacers  131  are fitted onto the two groups of supporting columns  132  of the positioning member  130  shown in  FIG. 14B , and the two spacers  131  are put in position. Next, two fiber array flat plates  120  are prepared, and the positioning through holes  122  in each are fitted respectively onto the two groups of supporting columns  132  of the positioning members  130 . The two fiber array plates  120  are thus positioned with a predetermined spacing between them such that the respective concave rows  121  that are formed in the two fiber array flat plates  120  are in alignment with each other. The above process makes up a first step.  
      Next, as is shown in  FIG. 18 , a second step is performed in which six fibers  140  are arrayed individually so as to span the aligned concave rows  121 , namely, such that the fibers  140  do not cross each other or overlap each other.  
      Thereafter, a third step is performed in which, as is shown in  FIG. 19 , other fiber array flat plates  120  are stacked respectively on top of the two fiber array flat plates  120  that have been positioned by the positioning member  130  and in whose concave rows  121  individual fibers  140  have been arrayed.  
      It is also possible to follow this third step with a fourth step in which tension is imparted to each of the arrayed fibers  140 , however, prior to this, as is shown in  FIG. 20 , it is preferable that a temporary fixing step is performed in which, by further stacking weight members  134  thereon, the tight contact between the first layer (i.e., the bottom most layer) of fiber array flat plates  120  and the second layer of fiber array flat plates  120  on top of the first layer is maintained.  
      If this type of temporary fixing is performed, the six arrayed fibers  140  do not spring out of the concave rows  121 , so that the subsequently performed fourth step can be performed stably and the work efficiency is improved.  
      Namely, the weight members  134 , which are heavy objects, are each placed on the stacked fiber array flat plates  120 . At this time, it is preferable that flat objects such as those shown in the drawings that have positioning through holes formed in the vicinity of both ends thereof and are able to be positioned using the supporting columns  132  are used for the weight members  134 , as this prevents the weight members  134  from being mispositioned or falling off.  
      The fourth step is a step in which tension is imparted to each of the arrayed fibers  140 , and is intended to prevent the fibers  140  from being fixed in a sagging state in the fiber fixing step that is performed after the fiber array step. Note that the size of the tension that is imparted here is within a range whereby the fibers  140  are not elastically deformed or broken.  
      An example of a method used to impart and maintain the tension to the fibers  140  is a method that uses a tension imparting device  160  such as that shown in  FIG. 21 .  
      This tension imparting device  160  is provided with a placement base  161  on which the positioning members  130  are placed and fixed, a fiber fixing section  162  that fixes one end  140   a  of the arrayed fibers  140 , and a fixing jig  163  that fixes while pulling the other end  140   b  of the fibers  140 . The fixing jig  163  is provided with a holding member  163   a  such as a clamp that holds the other end  140   b  of the fibers  140 , and an elastic body  163   b  such as a spring or a rubber member that is connected to the holding member  163   a . The elastic body  163   b  can be fixed to a flat plate  164  on which the placement base  161  is mounted, and this enables the fibers  140  to be maintained in a tensioned state. Note that, in  FIG. 21 , the symbol  165  indicates a guide member in the form of a round bar. This guide member  165  enables the direction in which the fibers  140  are pulled by the fixing jig  163  to be changed in a  90  degree downward direction, as is shown in  FIG. 21 . Accordingly, as is also shown in  FIG. 22 , even if four layers of fibers  140  are later arrayed and tension is imparted to each of the fibers  140 , it is still easy to secure a compact space on the base  164  for fixing the elastic bodies  163   b.    
      Furthermore, here, it is preferable that the heights of the tops of the guide members  165  are slightly lower than the heights of the bottom portions of the concave rows  121  formed in the fiber array flat plates  120 , so that not only is tension imparted in the longitudinal direction of the fibers  140  to each of the arrayed fibers  140 , but so that force is also acting in a direction in which the fibers  140  are pressed downwards onto the bottom portions of the concave rows  121 . By employing a structure such as this, tension is imparted to each fiber  140  to prevent each fiber from coming loose, and the fibers  140  can be prevented from springing out of the concave rows  121  even if the topmost layer of fiber array flat plates  120  or the weight members  134  are removed.  
      The fourth step is performed in this manner, so that the state shown in  FIG. 21  is obtained. As a result, the tasks of arraying the fibers  140  of the first layer in predetermined positions and imparting tension thereto are ended.  
      If the temporary fixing step using the weight members  134  is performed, after the two weight members  134  have been removed, the above described second step, namely, a step in which the fibers  140  are arrayed individually so as to span the aligned concave rows  121  is performed for the concave rows  121  of the second layer of fiber array flat plates  120 . Thereafter, by again performing the third step in the same manner, the temporary fixing step, if this is necessary, and the fourth step, the second layer of fibers  140  can be arrayed in predetermined positions.  
      Note that, in the arraying operation for each layer, it is also possible after the fourth step has ended to perform a fiber bonding step in which adhesive agent is put into the gaps between the already tensioned fibers  140  and the concave rows  121  where these tensioned fibers  140  are arrayed so as to bond the respective fibers to the concave rows  121 . This type of fiber bonding step can also be performed for the respective fibers  140  and the concave rows  121  of both of the fiber array flat plates  120  of each layer, however, it is preferable that the other end  140   b  side of the fibers  140  that are fixed by the fixing jig  163  is bonded to the concave rows of the fiber array flat plates  120 . The adhesive agent that is used here is preferably one that can be easily removed later from the fiber array flat plates  120 , and examples thereof include aqueous vinyl acetate based adhesive agents. By bonding the other end  140   b  side of the fibers  140  that are fixed by the fixing jig  163  to the concave rows of the fiber array flat plates  120 , when the work of inserting the curable resin solution is performed in the subsequent fiber fixing step, resin solution can be prevented from leaking from this bond portion.  
      In this manner, by repeating each of the above steps, the fibers  140  are arrayed as far as the fifth layer, and the state shown in  FIG. 22  in which tension is imparted to all of the fibers  140  is obtained. Note that after the fifth layer, namely, the topmost layer of the fibers  140  has been arrayed, then if another fiber array flat plate is to be placed on top thereof (i.e., in the third step), it is possible to stack spacers  131  in which no concave rows have been formed instead of the fiber array flat plate. A spacer  131  having sufficient strength is used for this topmost stacked spacer  131 , and the 5 stacked layers of fiber array flat plates  120  are sandwiched by this spacer  131  and the base  133  of the positioning member  130 . It is preferable if these are then fastened with bolts or screws so that the stacked state of the stacked fiber array flat plates  120  is maintained even in the subsequent fiber fixing step and the fiber array is not disturbed. Namely, it is preferable if the spacers  131  are used as presser plates. Moreover, instead of the spacers  131  that are stacked on the topmost layer as presser plates in this manner being fixed to the base  133  of the positioning member  130 , they can also be fixed to the spacers  131  beneath the first layer of fiber array flat plates  120  provided that the stacked state of the stacked fiber array flat plates  120  is fixed.  
      In the above description, the third step to stack other fiber array flat plates  120  is performed after the second step to array fibers  140  and prior to the fourth step to impart tension to these fibers  140 . However, after the second step, it is also possible to perform the third step after the fourth step has been performed. In this case, it is preferable that, prior to the fourth step, weight members  134 , such as those used in the temporary fixing step described above, whose contact surface with the fiber array flat plates  120  is a flat surface are used to prevent the respective fibers  140  from springing out from the concave rows  121  during the fourth step.  
      Next, the second embodiment of the fiber array step will be described.  
      In the second embodiment as well, firstly, as is shown in  FIG. 23 , the positioning through holes of two spacers  131  are fitted respectively onto the two groups of supporting columns  132  of the positioning member  130 , and the spacers  131  are put in position. Next, one fiber array flat plate  120  is prepared, and the positioning through holes  122  therein are fitted onto one group of the supporting columns  132  of the positioning member  130 . The fiber array plate  120  is thus positioned in a predetermined position. The above process makes up a first step.  
      Next, a second step is performed in which one other fiber array flat plate  120  is prepared, and one end  140   a  of each fiber  140  that has been cut to a predetermined length is arrayed individually in concave rows  121  and bonded, as is shown in  FIG. 24 , so that a fiber array flat plate  120 ′ on which the fiber bonding has already been completed is manufactured.  
      Here, the method used to bond the fibers  140  in the concave rows  121  is preferably a method in which an adhesive agent is thinly coated in advance in each concave row  121  and, thereafter, the one end  140   a  side of each fiber  140  is arrayed in the concave rows  121 . At this time, care is taken that the adhesive agent does not spill over into portions other than the concave rows  121  of the fiber array flat plate  120 , and if it does spill over, it is necessary that it be removed immediately. If adhesive agent is present in portions other than the concave rows  121  of the fiber array flat plates  120 , then it is not possible to stack other fiber array flat plates  120  in a stable manner on top of this fiber array flat plate  120 ′ on which the fiber bonding has already been completed. There is also a possibility that it will affect the array pitch of the fibers in the fiber array body  150  that is ultimately obtained.  
      Next, as is shown in  FIG. 25 , a third step is performed in which the other end (i.e., the free end)  140   b  sides of the fibers  140  that were arrayed and bonded in the concave rows  121  in the second step are arrayed individually in the concave rows of the fiber array flat plate  120  that was stacked on the positioning member  130  in the first step. The arraying operation here can be easily performed because the one end  140   a  side of the fibers  140  has already been bonded to the concave rows  121 .  
      Next, as is shown in  FIG. 26 , the fourth step is performed in which another fiber array flat plate  120  is stacked on top of the fiber array flat plate  120  that is already stacked on the positioning member  130  so that the respective fibers  140  arrayed here do not spring out from the concave rows  121 .  
      After the fourth step and prior to the fifth step, it is preferable that, as is shown in  FIG. 27 , a temporary fixing step is performed in which a weight member  134  such as that described in the first embodiment is placed on the fiber array flat plate  120  that was placed in a predetermined position in the fourth step, so that the state of close contact between the fiber array flat plate  120  of the first layer (i.e., the bottom most layer) and the fiber array flat plate  120  of the second layer is maintained. By performing this temporary fixing the six arrayed fibers  140  do not spring out from the concave rows, and the fifth step that is performed next can be performed stably and with improved work efficiency.  
      In the fifth step, as is shown in  FIG. 28 , the fiber array flat plate  120 ′ in which the fibers have already been bonded is positioned a predetermined distance apart such that the concave rows  121  that are formed in this fiber array flat plate  120 ′ are in alignment with the concave rows  121  of the fiber array flat plate  120  that has already been placed in a predetermined position. Next, a weight member  134  is also preferably placed on top of the fiber array flat plate  120 ′ in which the fiber bonding has already been completed.  
      Next, a sixth step is performed in which tension is imparted to each of the arrayed fibers  140  to a degree that does not cause the fibers  140  to be elastically deformed or to break.  
      In the sixth step, the same type of tension imparting device  160  as that used in the first embodiment is used and the same type of method to impart the tension can be used, however, at this time, the one end  140   a  side of the fibers  140  is already in a state of being bonded to the fiber array flat plates  120 ′ in which the fiber bonding is completed, and, furthermore, these fiber array flat plates  120 ′ in which the fiber bonding is completed are fixed by the supporting columns  132  so as not to move. Accordingly, because the fibers  140  do not move even if tension is imparted thereto, in the second embodiment, it is not necessary to fix the fibers  140  using the fiber fixing section  162 , and the other end  140   b  side is fixed in the fixing jig  163 .  
      By performing each of the above described steps, the first layer of fibers  140  can be arrayed in predetermined positions. By then repeating the second and subsequent steps in the same manner, the second and subsequent layers of fibers  140  can be arrayed in predetermined positions.  
      Moreover, once the arraying of the fibers  140  has been completed as far as the fifth layer, in the same way as in the case of the first embodiment, it is preferable that a spacer  131  in which no concave rows are formed and that can also act as a pressing plate is placed on the topmost layer. This spacer  131  and the base  133  of the positioning member  130  should then be fixed by bolts or screws, so that the stacked state of the stacked fiber array flat plates  120  is maintained and the array of fibers  140  is not disturbed.  
      Furthermore, in the array operation for each layer, after the sixth step has ended, as was described in the first embodiment, it is also possible to perform a fiber bonding step in which the respective fibers are bonded in the concave rows  121  by inserting an adhesive agent between the fibers  140  that have already been tensioned and the concave rows  121  where these tensioned fibers are arrayed. Note that when this type of fiber bonding step is performed, it is performed on the other end  140   b  side of the fibers  140  that are fixed by the fixing jig  163 .  
      In the above description concerning the second embodiment, the fourth, fifth, and sixth steps are performed in sequence on the other end  140   b  side of the bonded fibers  140  after the third step in which the fibers are arrayed individually in the concave rows  121  of the fiber array flat plate  120  that has already been placed in a predetermined position, however, it is also possible to perform the fourth step after the third and then the fifth steps have been performed, or after the third and then the fifth and sixth steps have been performed. In this case, it is preferable that the respective fibers  140  are prevented from springing out from the concave rows  121  during the fifth and sixth steps by using a weight member  134  such as that used in the first embodiment.  
      Note that a method that employs a winding mechanism  170  such as that shown in  FIGS. 29A and 29B  may be used as a method for efficiently manufacturing the fiber array flat plate  120 ′ shown in  FIG. 24  in which the fiber bonding has already been completed, namely, as a method for efficiently implementing the second step of the second embodiment.  
      This winding mechanism  170  is equipped with a fiber winding drum  171  that rotates around a shaft  171   a  in the direction of the arrow in  FIG. 29B . By continuously supplying fiber  140  from a bobbin  172  to this fiber winding drum  171 , the fiber  140  is wound onto the fiber winding drum  171 . The winding mechanism  170  is also provided with a movable unit  173  that moves along a movement shaft  173   a  that is provided in parallel with the shaft  171   a  of the fiber winding drum  171 . A first rotation guide  174  and a fiber guide nozzle  175  are fixed to this movable unit  173 . The symbols  176  and  177  in the drawings respectively indicate a second rotating guide and a third rotating guide.  
      The symbol  178  in the drawings indicates a dancer rotating guide. By moving in a vertical direction in the drawings, the dancer rotating guide  178  applies a constant tension that is not more than a yield load to the fibers  140  such that the fibers  140  do not sag.  
      Specifically, a braking force is placed on the supply of fibers  140  from the bobbin  172  such that the position of the dancer rotating guide  178  is kept constant. Namely, constant feedback is made to a brake (not shown) provided in the bobbin  172  as to the position in a vertical direction of the dancer rotating guide  178 , and the brake is loosened when the dancer rotating guide  178  rises up and is tightened when the dancer rotating guide  178  drops down. In addition to this, it is also possible to keep a constant tension using a tension detector that generates electrical signals corresponding to the tension acting on the fibers  140  being supplied.  
      When this type of winding mechanism  170  is used to manufacture the fiber bonded fiber array flat plate  120 ′ by individually arraying and bonding the one end  140   a  side of the fibers  140  that have been cut to predetermined lengths in the concave rows  121  of the fiber array flat plates  120 , firstly, a curable adhesive agent that has no effect on the material of the fibers  140  is coated in advance onto the concave rows  121  of a fiber array flat plate  120 . Next, this fiber array flat plate  120  is fixed onto the drum face of the fiber winding drum  171  such that the concave rows  121  are orthogonal to the shaft  171  a of the fiber winding drum  171 , and such that the surface on the side thereof where the concave rows  121  are not formed is in contact with the drum face. Fiber  140  is then supplied from the bobbin  172  to the fiber winding drum  171  via the second rotating guide  176 , the dancer rotating guide  178 , the third rotating guide  177 , the first rotating guide  174 , and the fiber guide nozzle  175  in that sequence, and the distal end of the fiber  140  is fixed to the drum face.  
      Next, the fiber winding drum  171  is continuously rotated in the direction shown by the arrow, and each time the fiber winding drum  171  rotates, the movable unit  173  is moved the same distance as the distance between adjacent concave rows  121  in one direction (i.e., the direction indicated by the arrow in  FIG. 29A ) along the shaft  171  a of the fiber winding drum  173 , and the fiber guide nozzle  175  that is fixed to the movable unit  173  is also moved in concert therewith.  
      By employing this structure, fibers are individually arrayed in sequence in all of the concave rows  121  starting from a concave row  121  positioned furthest to one end of the plurality of concave rows  121  of the fiber array flat plate  120  that is mounted on the fiber winding drum  171 .  
      After fibers have been arrayed in all of the concave rows, the arrayed fibers  140  are cut off outside the fiber array flat plate  120 . Consequently, a fiber array flat plate  120 ′ in which the fiber bonding has been completed can be removed from the fiber winding drum  171 .  
      Note that the curable adhesive agent that is coated here in advance in the concave rows  121  is a highly viscous adhesive agent whose curing speed is comparatively slow. If the concave rows  121  are coated with this type of adhesive agent, the fibers  140  are adhered by the viscosity of the adhesive agent. Accordingly, the adhesive agent can be cured after the fiber bonded fiber array flat plate  120 ′ has been removed from the fiber winding drum  171 .  
      In addition to this, it is also possible to use an ultraviolet curable adhesive agent for the curable adhesive agent. In this case, after fibers  140  have been arrayed in all of the concave rows  121 , the adhesive agent is cured by ultraviolet light irradiation prior to the fibers  140  being cut. Thereafter, the fiber bonded fiber array flat plates  120 ′ may be removed from the fiber winding drum  171 .  
      The method used to coat the concave rows  121  of the fiber array flat plates  120  in advance with these curable adhesive agents may be a method in which the concave rows  121  are coated with the adhesive agents by hand. However, it is also possible to provide a roll coater or dispenser on the winding mechanism  170  so that the fiber  140  supplied from the bobbin  172  or the concave rows  121  of the fiber array flat plate  120  that is fixed to the fiber winding drum  171  can be automatically coated with adhesive agent.  
      In the winding mechanism  170  of this example, by moving the movable unit  173  in order to array fibers  140  in sequence in the plurality of concave rows  121 , the fiber guide nozzle  175  that is fixed to the movable unit  173  moves uniformly along the shaft  171  a of the fiber winding drum  171 , however, it is also possible to not move the fiber guide nozzle  175 , and, instead, to move the fiber winding drum  171  uniformly along the shaft  171   a.    
      (Fiber Fixing Step)  
      In the method of manufacturing the fiber array body of the present invention, after the above described fiber array step, a fiber fixing step is performed in which the fibers  140  that were arrayed three-dimensionally in the fiber array step are fixed as they are without any further modification. A description will now be given of a fiber fixing step using as an example a method in which spaces between three-dimensionally arrayed fibers  140  are filled with curable resin which is then cured.  
      Firstly, as is shown in  FIG. 30 , by performing the fiber array step,  30  fibers  140  are arrayed in their respective concave rows and tension is imparted thereto. A potting block  190  is then placed so as to enclose portions of these fibers  140  that are suspended between two stacked objects  180   a  and  180   b  that are obtained by stacking the fiber array flat plates  120  in five layers.  
      In this example, as is shown in  FIG. 31 , the potting block  190  is formed in a cylindrical shape by combining four plate shaped block pieces  190   a ,  190   b ,  190   c , and  190   d  in the manner shown in the drawing.  
      The four block pieces  190   a ,  190   b ,  190   c , and  190   d  of this example are formed from a metal such as aluminum, and release processing is performed on those surfaces of the block pieces that come into contact with each other and on those surfaces of the block pieces that form interior wall surfaces when the four pieces are combined into a cylinder shape. Examples of the method used to perform this release processing include a method in which, as is shown in the drawings, a sheet-shaped object  191  formed from highly non-adhesive Teflon (registered trademark), polyethylene, or polypropylene or the like is adhered onto each surface, as well as a method in which a coated resin membrane is formed by coating these resins on each surface. If release processing is preformed in this manner, then after a curable resin solution is later poured inside the potting block  190  and is then cured, the potting block  190  can be easily released from the cured resin. Moreover, instead of performing this release processing on the block pieces  190   a ,  190   b ,  190   c , and  190   d , it is also possible to form the potting block itself from a highly non-adhesive resin.  
      A semi-conical notch  192  that becomes wider towards one end thereof is formed in one surface of the inner wall surfaces of the cylindrical potting block  190 . As is described below in detail, this notch  192  forms a filling aperture when a curable resin is poured into the potting block  190  so as to fill it. Note that, in  FIG. 31 , in order to make the configuration of the potting block  190  easier to understand, the fasteners used to fix the potting block  190 , the 30 fibers, and the tension imparting device and the like are omitted from the drawing. The 30 fibers, in actual fact, extend in a left-right direction in the drawing inside a hollow portion of the potting block that is indicated by the symbol  193 .  
      As is shown in  FIG. 30 , the potting block  190  that is made up of the four block pieces  190   a ,  190   b ,  190   c , and  190   d  is fixed by fasteners  194  such as bolts or screws so as to enclose the 30 fibers  140 , and so that the one end of the potting block  190  where the filling aperture is not formed is in close contact with the one stacked object  180   a  of fiber array flat plates  120 . At this time, a sealing member  195  formed from silicon rubber or the like that has peelability and elasticity is interposed so that the curable resin solution that is supplied later does not leak out from the close contact portion between the potting block  190  and the stacked object  180   a.    
      After this, as is shown in  FIG. 32 , the potting block  190  is stood upright together with the 30 fibers  140 , the fiber array jig  110 , and the tension imparting device  160  such that the end of the potting block  190  on the side where the filling aperture is formed (i.e., the aperture end) is positioned facing upward.  
      A spout of a cup  196  that contains curable resin solution is placed against the filling aperture that is formed in the potting block  190  by the semi-conical notch  192 , and the curable resin solution is poured into the hollow portion  193  of the potting block  190  so as to spread along the internal wall surfaces of the potting block  190 . Subsequently, the potting block  190  is left undisturbed at a predetermined temperature for a predetermined length of time so that the supplied curable resin solution is able to cure.  
      The method used to fill the interior of the potting block  190  with the curable resin solution may also be a method such as that shown in  FIG. 33 .  
      Namely, a resin pouring aperture that is used to pour in resin is formed in a side wall of the potting block  190  in the vicinity of one end on the side that is blocked by being placed in tight contact with the stacked object  180   a . Next, a tube  198  is prepared and one end of this tube  198  is inserted into the resin pouring aperture. The other end of the tube  198  is connected to a funnel  199 . By then pouring curable resin solution into the funnel  199 , the curable resin solution gradually fills the interior of the potting block  190  from bottom to top.  
      Note that when the curable resin solution is being used in this manner, it is preferable that the curable resin solution is stirred and degassed in advance in a vacuum. If it is degassed, there are no air gaps inside the resin after it has cured and the resin sufficiently permeates the space between the fibers  140 . It is even more preferable if the curable resin solution is sufficiently degassed and if the above described resin pouring task is conducted under reduced pressure.  
      After the curable resin solution with which the interior of the potting block  190  has been filled has cured, the potting block  190  is disassembled into the four block pieces  190   a ,  190   b ,  190   c , and  190   d . The fiber array body  150  that is made up of the 30 fibers  140  and the curable resin  151  that fixes the fibers  140  is separated from the tension imparting device  160  and the respective fiber array flat plates  120 . By then cutting the fibers  140  as is appropriate, a fiber array body  150  in a state such as that shown in  FIG. 16 , or in a state such as that shown in  FIG. 34  or  FIG. 35  can be obtained.  
      The type of curable resin that is used here is preferably a curable resin solution that is in a low viscosity state at normal temperature and that is able to fill the hollow portion  193  of the potting block  190  and then cure at room temperature, and that after curing is able to be sliced easily by a cutter or the like into thin pieces having a uniform thickness. Furthermore, the obtained thin pieces should preferably have sufficient hardness and elasticity that they do not become chipped or broken. Examples of this type of curable resin include two-liquid reaction curable resins such as urethane resins.  
      (Fiber)  
      A description has been given above of a fiber array step in which a plurality of fibers  140  are arrayed three-dimensionally, and a fiber fixing step in which the three-dimensionally arrayed fibers  140  are fixed. There is, however, no particular restriction as to the type of fiber that is arrayed and then fixed in the manner described above. Examples thereof include chemical fibers such as synthetic fibers, semisynthetic fibers, regenerated fibers, and inorganic fibers as well as natural fibers.  
      Representative examples of synthetic fibers include: various types of polyamide based fibers such as nylon 6, nylon 66, and aromatic polyamides; various types of polyester based fibers such as polyethylene terephthalate, polybutylene terephthalate, polylactic acids, and polyglycolic acids; various types of acrylic based fibers such as polyacrylonitrile; various types of polyolefin based fibers such as polyethylene and polypropylene; various types of polyvinyl alcohol based fibers; various types of polyvinylidene chloride based fibers; various types of polyvinyl chloride based fibers and polyurethane based fibers; phenol based fibers; fluorine based fibers such as polyvinylidene fluoride and polytetrafluoroethylene; polyalkylene paraoxybenzoate based fibers; fibers that use (meth)acrylic based resins such as polymethyl methacrylate; and fibers that use polycarbonate based resins.  
      Representative examples of semisynthetic fibers include: various types of fibers that are based on cellulose based derivatives that use diacetate, triacetate, chitin, or chitosan as a raw material; and various types of protein based fibers that are known as promix.  
      Representative examples of regenerated fibers include various types of cellulose based regenerated fibers such as rayon, cupra, and polynosic that are obtained using a viscose method, a copper-ammonia method, or an organic solvent method.  
      Representative example of inorganic fibers include glass fibers, and carbon fibers.  
      Representative examples of natural fibers include: vegetable fibers such as cotton, flax, ramie, and jute; animal fibers such as wool and silk; and mineral fibers such as asbestos.  
      These fibers  140  can be used as is appropriate in the manufacturing of the fiber arrayed bodies  150 , however, as is described above, because tension is imparted to the fibers  140  in the fiber array step, of the fibers that are described above, polycarbonate based fibers, polyester based fibers, nylon based fibers, and aromatic polyamide fibers and the like that have a high modulus of elasticity and yield strength are preferably used.  
      Any fibers other than natural fibers that are obtained from a known fiber forming technology such as a melt spinning method, a wet spinning method, and a dry spinning method, or from a combination of these technologies can also be used.  
      Furthermore, unprocessed fibers may be used without any modification thereto for the fibers  140 , however, if necessary, fibers into which a reactive functional group has been introduced may be used, or fibers that have undergone plasma processing or irradiation processing using γ-rays or electron beams or the like may be used.  
      Moreover, there is no particular restriction as to the form of the fibers  140 , and they may be in monofilament form or in multifilament form. In addition, the fibers  140  may be formed by spun yarn obtained by spinning short fibers. The fibers  140  may also be hollow fibers or fibers having a porous structure. Hollow fibers can be manufactured using a known method that employs special nozzles.  
      There is no particular restriction as to the outer diameter of the fibers  140  and fibers  140  having the desired outer diameter can be used. However, if the outer diameter is too small, breakages tend to occur and there is a deterioration in the ease of handling. On the other hand, the smaller the outer diameter of the fibers  140 , the higher the density at which the fibers  140  are able to be arrayed. Accordingly, the outer diameter of the fibers  140  is set so as to provide both ease of handling and the desired arrayed density. Preferably, the outer diameter of a single fiber is 500 μm or less, and more preferably 300 to 100 μm. If a multifilament fiber is used for the fibers  140 , then 83 dtex/36 filament or 82 dtex/45 filament or the like can be used without any modification.  
      For example, as is described below, a monofilament fiber having an outer diameter of 150 μm is used for the fibers  140  when an organism related substance fixed microarray is being manufactured from the fiber array body  150 . When this monofilament fiber is arrayed at an array pitch of 200 μm, the number of fibers  140  that can be arrayed inside a 1 cm 2  square is 2400. Accordingly, by fixing one type of organism related substance in one single fiber, it is possible to fix 2400 types of organism related substance in each square centimeter. Moreover, if monofilament porous fibers, monofilament hollow fibers or monofilament porous hollow fibers having an outer diameter of approximately 200 μm are arrayed at an array pitch of 300 μm, a fiber array body  150  in which approximately 1000 fibers  140  are arrayed in each square centimeter can be obtained. Accordingly, by fixing one type of organism related substance in one single fiber, it is possible to fix 1000 types of organism related substance in each square centimeter.  
      [Method of Manufacturing an Organism Related Substance Fixed Microarray] 
      Next, a description will be given of a method of manufacturing an organism related substance fixed microarray from a fiber array body  150  obtained by performing the above described fiber array step and fiber fixing step.  
      In the fiber array step and fiber fixing step, if a fiber in which an organism related substance has previously been fixed is used as the three-dimensionally arrayed and fixed fiber  140 , then by slicing the fiber array body  150  that is obtained, such as that shown in  FIG. 16 , into thin pieces in a direction intersecting the fibers  140 , as is shown in  FIG. 36 , the fibers  140  in which organism related substance has been fixed are fixed by curable resin, and thin slices of an organism related substance fixed microarray  200  can be obtained on both surfaces of which is exposed a cross-section of the fibers  140 . The direction of the slices should be a direction that intersects the longitudinal direction of the fibers  140 . Preferably, it should be a direction that is perpendicular to the longitudinal direction of the fibers  140 .  
      If the organism related substance fixed in the fibers  140  is, for example, a nucleic acid, then by providing a specimen for the obtained organism related substance fixed microarray  200  and performing hybridization, it is possible to detect a specific nucleic acid array present in the specimen using the nucleic acid fixed to the fibers as a probe.  
      Note that if a multifilament fiber or spun yarn or the like is used for the fibers  140 , then it is possible to fix organism related substance in the gaps between the individual fibers. Moreover, if a hollow or porous fiber is used for the fibers  140 , then it is possible to fix organism related substance in the hollow portions or in the gaps within the fibers  140 .  
      If, on the other hand, in the fiber array step and fiber fixing step, a fiber in which an organism related substance has not previously been fixed is used as the three-dimensionally arrayed and fixed fiber  140 , then a fiber array body  150  is obtained in the state shown in  FIG. 34  or  FIG. 35 , namely, in a state in which at least one end of the fibers  140  extends beyond the curable resin  151  , and after the organism related substance has been fixed in each fiber  140  of this fiber array body  150 , the fiber array body  150  is sliced into thin pieces in a direction intersecting the fibers  140 .  
      An example of a method used to fix organism related substance in the respective fibers  140  of the fiber array body  150  shown in  FIG. 34  in which fibers  140  in which organism related substance has not been fixed are arrayed is the method shown in  FIG. 37 . This method is effective when porous fibers, hollow fibers, or porous hollow fibers are used for the fibers  140  that by reducing the pressure at one end of the fibers allow a liquid to be suctioned from the other end of the fibers.  
      Firstly, the same number of containers  197  as the number of the fibers  140 , namely, in this case 30 containers  197  are prepared, and a solution that contains an organism related substance is placed inside each container  197 . The ends of the fibers  140  that extend from the curable resin  151  of the fiber array body  150  are immersed individually into the containers  197  containing the solution. By then suctioning the solution from the other end of the fibers  140 , the solution containing the organism related substance in the hollow portion or porous portion of each fiber  140  is suctioned up and the organism related substance can be introduced into each fiber  140 . The type of organism related substance that is introduced into each fiber  140  may be different in every single one of the 30 fibers  140 . It is also possible to group together a plurality of fibers and introduce the same type of organism related substance into that group.  
      Examples of the organism related substance that is introduced into the fibers  140  in this manner include nucleic acids such as deoxyribonucleic acid (DNA), ribonucleic acid (RNA), peptide nucleic acid (PNA), and oxypeptide nucleic acid (OPNA) as well as proteins and polysaccharides. The organism related substance used may be one that is commercially available, or one that is obtained from living cells.  
      If a nucleic acid is used as the organism related substance, the DNA or RNA from living cells may be prepared using a known method. For example, DNA may be extracted using Blin&#39;s method (see Blin et. Al., Nucleic Acids Res. 3: 2303 (1976)). RNA may be extracted using Favaloro&#39;s method (see Favaloro et. Al., Methods Enzymol. 65: 718 (1980)).  
      It is also possible to use chain or toroidal plasmid DNA or chromosome DNA, DNA pieces obtained by slicing these using restriction enzymes or by chemically slicing them, DNA that has been synthesized by enzymes in a test tube, or else chemically synthesized DNA.  
      These various organism related substance types may be used unmodified as they are, or they may be used in the form of derivatives in which the organism related substance has undergone chemical modification, or, if necessary, they may transformed and then used. For example, if a nucleic acid is used for the organism related substance, then amino formation, biotin formation, digoxigenin formation and the like, which are known as methods for chemically modifying organism related substance (Current Protocols in Molecular Biology, Ed.; Frederick M. Ausubel et. al. (1990) and Deisotoping Experimental Protocols (1) DIG Hybridization (Shuujunsha)), can be employed.  
      After the organism related substance has been introduced into the fibers  140 , the method that is used to fix it therein is able to utilize the various types of chemical or physical interaction between the fibers  140  and the organism related substance, namely the chemical or physical interaction between the functional groups belonging to the fibers  140  and the constituents forming the organism related substance.  
      If porous fibers, hollow fibers, or porous hollow fibers are used for the fibers  140 , then after the solution that contains the organism related substance has been suctioned and introduced into the hollow portion or porous portion of the fibers  140  constituting the fiber array body  150  using the above described method or the like, the organism related substance can be fixed to these fibers  140  using the interaction between functional groups present on the internal wall surfaces and the like of the hollow portions or porous portions of the fibers  140  and the constituents making up the organism related substance.  
      If an unmodified nucleic acid is fixed to the fibers  140 , then, after the nucleic acid and the fibers  140  have interacted, they can be fixed by baking or ultraviolet light irradiation. If a nucleic acid modified by an amino group is fixed to the fibers  140 , then this can be coupled with functional groups of the fibers using a cross linking agent such as glutaraldehyde or 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC). Furthermore, it is also possible to transform the fixed organism related substance by performing heat processing, alkaline processing, surfactant processing or the like. If organism related substance obtained from raw material such as cells or biomass is used, then it is also possible to perform processing such as removing unnecessary cell components. Note that these processings may be performed separately or may be performed simultaneously. Moreover, the organism related substance may be fixed in the fibers  140  after these processings have been performed on samples containing the organism related substance.  
      As has been described above, when a plurality of fibers  140  are being arrayed three-dimensionally, the fiber array jig  110  that is used has a plurality of fiber array plates  120  on one surface of which are formed substantially in parallel with each other a plurality of concave rows  121  in each one of which is arrayed a single fiber  140 , and has a positioning member  130  that is used to place these fiber array plates  120  in predetermined positions. At least two of the fiber array flat plates  120  are positioned apart from each other by the positioning member  130  such that the concave rows  121  formed in each fiber array flat plate  120  are in alignment with each other, and one or more of the other fiber array flat plates  120  are stacked one by one on top of these fiber array flat plates  120 . As a result, the fibers  140  can be arrayed at a high density, with a high degree of accuracy, and extremely efficiently, and it also becomes possible to mass produce the fiber array bodies  150  for industry. Namely, if this type of fiber array jig  110  is used, it is not necessary to perform the complex task of inserting individual fibers through holes formed in a jig, as is the case conventionally. Moreover, because it is not necessary to guide the fibers being inserted into the holes using forceps or the like, the problem of fibers that have already being inserted into adjacent holes obstructing the operation when inserting fibers using forceps does not arise. In addition, because the operation is not one of inserting the fibers  140  into holes, but of arraying them in the concave rows  121 , even if the outer diameter of the fibers is narrow and they have low rigidity, they can be arrayed easily so that a greater degree of density in the array of the fibers  140  becomes possible.  
      Moreover, when this type of fiber array jig  110  is used, the work involved in the fiber array step can be divided so that, from this viewpoint as well, the productivity of the fiber array body  150  is improved.  
      For example, if the above described fiber array step is performed using the second embodiment, then the task can be divided into a step in which fiber bonded fiber array flat plates  120 ′ can be continuously manufactured in large volume using the winding mechanism  170  shown in  FIGS. 29A and 29B , and all steps other than this step. As a result, different operators are able to advance the work simultaneously. In contrast, in work in which the fibers are inserted one by one in a jig in which holes are formed, as is the case conventionally, the entire task of inserting all of the fibers in sequence is just one step and it is difficult for the labor involved therein to be divided. As a result, the work efficiency is poor.  
      Namely, by using the fiber array jig  110  described above, even if the outer diameter of the fibers  140  is small and they are difficult to handle, they can still be arrayed accurately at a high density and also efficiently, and mass production of the fiber arrayed bodies is possible because the manufacturing tasks can be performed separately. As a result, it is also possible to mass produce organism related substance fixed microarrays that enable a large variety of samples to be analyzed.  
     EXAMPLES  
      The present invention will now be described specifically using the examples given below.  
     Reference Example 1  
      Probe A and probe B below were synthesized.  
                                          Probe A   gcgatcgaaa ccttgctgta cgagcgaggg ctc                               (array number 1)                       Probe B   gatgaggtgg aggtcagggt ttgggacagc ag                           (array number 2)          
 
      The synthesis of the oligonucleotides was performed using an automatic DNA/RNA synthesizer (model 1394) manufactured by PE Biosystems. In the final step of the DNA synthesis, an aminohexyl group [NH 2 (CH 2 ) 6 —] was introduced into the 5′ terminal of the respective nucleotides using an aminolink II (trade name—manufactured by Applied Biosystems).  
     Reference Example 2  
      A solution A formed from the composition described below was prepared. PMMA monoacrylate (molecular weight 6000): 5 parts by mass Toluene: 95 parts by mass  
     Reference Example 3  
      A solution B formed from the composition described below was prepared. 
      Acrylamide: 9 parts by mass     N,N′-methylene bisacrylamide: 1 part by mass     2,2′-azobis(2-methylpropionamidine)dihydrochloride (V-50): 0.1     parts by mass     water: 90 parts by mass    

     Example 1  
      (1) Introduction and Fixing of Organism Related Substance in A Hollow Fiber  
      A hollow fiber made out of nylon (i.e., a melt spun product made of nylon 6 having an outer diameter of 0.28 mm, and an inner diameter (i.e., the diameter of the hollow portion) of 0.2 mm) was cut into 700 mm lengths so that 900 nylon hollow fibers were prepared. Formic acid was suctioned from one end of these hollow fibers into the hollow portion thereof and was held therein for one minute. Next, a large volume of water at room temperature was poured into the hollow portions so that the hollow portions were properly washed, and they were then dried. This constituted the preprocessing of the nylon hollow fibers.  
      The oligonucleotide probe A and probe B having amino groups that were synthesized in Reference example 1 were fixed to the internal walls of the nylon hollow fibers that had undergone preprocessing. Specifically, a solution obtained by adding probe A to a potassium phosphate buffer solution was introduced via one end portion of 450 hollow fibers, while a solution obtained by adding probe B to a potassium phosphate buffer solution was introduced via one end portion of the other 450 hollow fibers. These were then kept overnight at 20° C.  
      Thereafter, interior portions of the nylon hollow fibers were washed in a potassium phosphate buffer solution and a potassium chloride aqueous solution, so that nylon hollow fibers to which organism related substance was fixed were obtained with probe A being fixed to the internal wall surfaces of 450 hollow fibers and probe B being fixed to the internal wall surfaces of 450 hollow fibers.  
      (2) Manufacturing of Hollow Fiber Array Body to which Organism Related Substance has been Fixed  
      (i) Fiber Array Step  
      A fiber array step was performed following the first embodiment that was described using FIGS.  17  to  22 , so that 900 nylon hollow fibers to which organism related substance had been fixed were arrayed in 30 rows multiplied by 30 layers.  
      Specifically, 60 flat plates made of SUS 304 spring steel having a width of 30 mm, a length (i.e., the direction of the concave rows) of 10 mm, and a thickness of 0.42 mm, and in which 30 concave rows  121  having a width of 0.3 mm and a depth of 0.3 mm were formed in parallel at a pitch of 0.42 mm, and in which positioning through holes  122  having a diameter of 4 mm were formed in the vicinity of the two side ends (i.e., in the transverse direction) thereof were used as the fiber array flat plates  120  of the fiber array jig  110 .  
      Two groups (with two columns in each group) of supporting columns  132  were erected on a base  133  made from a rectangular flat plate, and this was used as a positioning member  130  for positioning the above fiber array flat plates  120  in predetermined positions. Note that the gap between one group of supporting columns and the other group of supporting columns was 150 mm.  
      In addition, flat plates that had a thickness of 15 mm and that, apart from the fact that concave rows were not formed therein, were the same size as the fiber array flat plates  120 , and in which the positioning through holes were formed in the same manner were prepared as spacers  131 .  
      Note that nylon hollow fibers having probe A fixed to the internal walls thereof and nylon hollow fibers having probe B fixed to the internal walls thereof were arrayed in parallel alternatingly in the concave rows  121  of each fiber array flat plate  120 . In addition, a temporary fixing step was performed for each layer using 1 kg weight members  134 .  
      The tension imparting device  160  shown in  FIG. 21  was used to impart tension to each fiber, and tension was imparted such that a load of 15N acted on each nylon hollow fiber, and each fiber was pulled such that there was no sagging in any of the fibers.  
      Furthermore, in the task of arraying each layer, after the fourth step had ended, a fiber bonding step was performed in which the weight member  134  on the fixing jig  163  side and the fiber array flat plate  120  beneath it are temporarily removed, and the respective fibers are bonded to the concave rows  121  by coating an adhesive agent between the hollow fibers and the concave rows  121  where these hollow fibers are arrayed. A water soluble vinyl acetate based adhesive agent (“Fast Dry” used for bonding wood: Konishi (Ltd.)) was used for the adhesive agent, and this was smeared on so as to sufficiently cover the spaces between the adhesive agent, the concave rows, and the hollow fibers using a squeegee equipped with a urethane blade. After the adhesive agent was smeared on in this manner, the fiber array flat plate  120  and the weight member  134  were put back in place and pressure was applied for several seconds at a load of approximately 200N.  
      After the 30th layer of fibers was arrayed, then if another fiber array flat plate is to be placed on top thereof (i.e., in the third step), a spacer  131  in which no concave rows have been formed can be stacked instead of the fiber array flat plate and used as a presser plate. Namely, the spacer  131  that is stacked on the topmost layer is fixed by screws to the base  133  of the positioning member  130 .  
      (ii) Fiber Fixing Step  
      As is shown in  FIG. 32 , the hollow portion  193  of the potting block  190  was filled with a curable resin solution.  
      Specifically, two aluminum plates (a) having a thickness of 11.1 mm, a width of 50 mm, and a length of 100 mm and two aluminum blocks (b) having a thickness of 19.5 mm, a width of 14.8 mm, and a length of 100 mm making a total of four pieces were used for the potting block  190 . Release processing was performed on the potting block  190  using Teflon (registered trademark) adhesive tape (Nitoflon adhesive tape: manufactured by Nitto Denko (Ltd.)) having a thickness of 0.13 mm and a width of 50 mm. Namely, Teflon (registered trademark) adhesive tape was stuck onto the surfaces (i.e., the surfaces having a width of 50 mm and a length of 100 mm) of the aforementioned two aluminum plate (a) pieces and onto the three surfaces (i.e., three of the four surfaces having a thickness of 19.5 mm and a length of 100 mm) of the aforementioned two aluminum block (a). Note that a filling aperture that is formed by a semi-conical notch  192  is formed at one end of one surface of one of the aluminum plates (a) and Teflon (registered trademark) adhesive tape is stuck onto this surface.  
      These four pieces were then combined in the manner shown in  FIG. 31  so as to enclose the 30 rows by 30 layers of organism related substance fixed nylon hollow fibers arrayed in the above described (i), and a 20 mm×20 mm×100 mm hollow portion  193  was formed by the potting block  190 . Note that silicon packing having a thickness of 1 mm was used as the sealing member  195  that was interposed such that the supplied curable resin solution did not leak from the portion of tight contact between the potting block  190  and the stacked object  180   a . The silicon packing was the same shape as the end surface of the potting block  190  and, in the same way, is provided with a 20 mm×20 mm aperture portion of which a portion was cut open. This cut open portion was opened up and arranged so as to span across the 30 rows by 30 layers of nylon hollow fibers. In addition, the stacked object  180   a  and the potting block  190  were fastened together under pressure by the fasteners  194  in the form of screws.  
      A two-solution polyurethane resin (curing agent: Nipporan 4276, main agent: coronate 4403 with two parts by mass of carbon black as an additive, mixture proportion: curing agent  38  parts by mass to main agent  62  parts by mass, manufactured by Japan Polyurethane Industries (Ltd.)) that had been degassed by being stirred and mixed in a vacuum was poured from the cup  196 , as is shown in  FIG. 32 , into the hollow portion  193  of the potting block  190  along internal wall surfaces of the potting block  190 .  
      In this state, after the resin was cured by being kept at room temperature for 16 hours, the potting block  190  was disassembled into four pieces, and a fiber array body made of nylon hollow fibers having the configuration shown in  FIG. 16  (i.e., having 30 rows by 30 layers) was obtained in which gaps between the nylon hollow fibers were filled with polyurethane resin, and whose cross-sectional dimensions were 20 mm×20 mm×length of 80 mm, and in which organism related substance was fixed to the interior walls.  
      In addition, by slicing this fiber array body in thin pieces having a thickness of 0.5 mm, approximately  140  organism related substance fixed microarrays were obtained.  
     Example 2  
      (1) Manufacturing of Hollow Fiber Array Body to which Organism Related Substance has not been Fixed  
      (i) Fiber Array Step  
      A fiber array step was performed following the second embodiment that was described using FIGS.  23  to  30 , so that 900 polycarbonate hollow fibers to which organism related substance had not been fixed were arrayed in 30 rows by 30 layers.  
      Specifically, the same fiber array jig  110  as in Example 1 was used, and fibers were bonded in the respective concave rows  121  of  30  of the fiber array flat plates  120  thereof so that  30  fiber bonded fiber array flat plates  120 ′ in which  30  fibers were bonded were prepared. The winding mechanism  170  shown in  FIGS. 29A and 29B  was used in the preparation of the  30  fiber bonded fiber array flat plates  120 ′. Namely, fiber array flat plates  120  the concave rows  121  of which had been coated with a water soluble vinyl acetate based adhesive agent (“Fast Dry” used for bonding wood: Konishi (Ltd.)) were fixed to the fiber winding drum (having a diameter of 320 mm)  171  of the fiber winding mechanism  170  shown in  FIGS. 29A and 29B . Polycarbonate hollow fibers (i.e., a melt spun product made of polycarbonate with an additive of one part by mass of carbon black and having an outer diameter of 0.28 mm, and an inner diameter of the hollow portion of 0.16 mm) were then unwound from the bobbin  172  onto which they were wound such that tension of 0.1 N was acting thereon, and were consecutively inserted into the 30 concave rows  121  of the fixed fiber array flat plates  120 .  
      Next, the adhesive agent that was squeezed out from the concave rows  121  by the insertion therein of the polycarbonate hollow fibers was spread fully over the concave rows  121  by a squeegee equipped with a urethane blade, and excess adhesive agent was totally removed. Thereafter, the polycarbonate hollow fibers were cut at a portion thereof 30 cm distant from the fiber array flat plates  120  in parallel with the shaft  171   a  of the fiber winding drum  171 , and the fiber bonded fiber array flat plates  120 ′ were removed from the fiber winding drum  171 . The fiber bonded fiber array flat plates  120 ′ that were obtained were then stored in a suspended state using the positioning through holes formed in the fiber bonded fiber array flat plates  120 ′ such that the polycarbonate hollow fibers did not become entangled with each other.  
      This operation was then repeated 30 times. As a result, 30 polycarbonate hollow fiber bonded fiber array flat plates  120 ′ in which 30 polycarbonate hollow fibers were bonded in the concave rows  121  were obtained.  
      PMMA monoacrylate was then introduced into the internal walls of each hollow fiber of the  30  fiber bonded fiber array flat plates  120 ′ that were obtained.  
      Specifically, one end of each of the  30  polycarbonate fibers of the fiber bonded fiber array flat plates  120 ′ was immersed in a semi cylindrical container containing the solution A prepared in Reference example 2. The other end of the 30 polycarbonate fibers were first aligned in parallel with the adhesive agent side of a silicon tape having a width of 20 mm, a length of 50 mm, and a thickness of 1 mm and having an adhesive agent provided on one side thereof. The fibers were then wound onto the tape in a columnar shape in their longitudinal direction and were cut in a substantially perpendicular direction relative to the fibers in a central portion in the longitudinal direction of the columnar shape. As a result, end surfaces of the 30 hollow fibers were exposed. Next, these end surfaces were press-inserted respectively into one end of polycarbonate pipes having an inner diameter smaller than the diameter of the end surfaces. The other ends of these pipes were then connected to a vacuum pump via a trap and the solution A was suctioned by reduced pressure into the polycarbonate hollow fibers.  
      After the solution introduced into the polycarbonate hollow fibers was removed to the trap, the one end of each of the polycarbonate hollow fibers was removed from the containers containing the solution A and, in that state, the vacuum pump was operated. In this manner, air was suctioned into the hollow fibers, resulting in solvent on the polycarbonate hollow fiber internal walls being evaporated and PMMA monoacrylate being introduced onto the hollow fiber internal walls  900  fibers were arrayed in 30 rows by 30 layers by performing the fiber array step in accordance with the second embodiment using the 30 fiber bonded fiber array flat plates  120 ′ in which 30 hollow fibers having PMMA monoacrylate introduced onto the internal walls thereof that were obtained in the above manner were bonded to concave rows  121 , and using the 30 fiber array flat plates  120  to which fibers had not been bonded, and using the same positioning member  130  as that used in Example 1.  
      Furthermore, in the task of arraying each layer, after the sixth step had ended, a fiber bonding step was performed in which the weight member  134  on the fixing jig  163  side and the fiber array flat plate  120  beneath it are temporarily removed, and the respective fibers are bonded to the concave rows  121  by coating the same adhesive agent as that used in Example 1 between the hollow fibers and the concave rows  121  where these hollow fibers are arrayed. After the adhesive agent was smeared on in this manner, the fiber array flat plate  120  and the weight member  134  were put back in place and pressure was applied for several seconds at a load of approximately 200N.  
      After the 30th layer of fibers was arrayed, then only if another fiber array flat plate is to be placed on top thereof (i.e., in the fourth step), a spacer  131  the same as that of Example 1 in which no concave rows have been formed can be stacked instead of the fiber array flat plate and used as a presser plate. Namely, the spacer  131  that is stacked on the topmost layer is fixed by screws to the base  133  of the positioning member  130 . The same tension imparting device  160  as in Example 1 was then used and tension was imparted to each fiber such that a load of 15N acted thereon.  
      (ii) Fiber Fixing Step  
      As is shown in  FIG. 33 , the hollow portion  193  of the potting block  190  was filled with a curable resin solution.  
      Specifically, using the same potting block  190  as that used in Example 1, the same Teflon (registered trademark) adhesive tape as in Example 1 was stuck thereon. However, unlike Example 1, instead of the filling aperture, a single aluminum plate (a) having a circular resin pouring aperture with a diameter of 9.8 mm formed therein was used. The resin pouring aperture was formed in the center in the transverse direction of the aluminum plate (a) at a position 12 mm from one of the short sides thereof. In addition, the Teflon (registered trademark) adhesive tape was cut out in the shape of the resin pouring aperture such that the Teflon (registered trademark) adhesive tape did not block the resin pouring aperture. These four pieces were then combined in the same manner as in Example 1 so as to enclose the 30 rows by 30 layers of polycarbonate hollow fibers to which organism related substance had not been fixed that were arrayed in the above described (i) as is shown in  FIG. 33 , and a 20 mm×20 mm×100 mm hollow portion  193  was formed by the potting block  190 . Note that the same sealing member  195  as in Example 1 was interposed into the portion of tight contact between the potting block  190  and the stacked object  180   a  such that the supplied curable resin solution did not leak from that portion. In addition, the stacked object  180   a  and the potting block  190  were fastened together under pressure by the fasteners  194  in the form of screws.  
      As is shown in  FIG. 33 , one end of a vinyl tube  198  having an outer diameter of 10 mm and an inner diameter of 8 mm was pushed into the resin pouring aperture formed in the aluminum plate (a) and the other end thereof was connected to a funnel  199 . The same two-solution polyurethane resin as was used in Example 1 that had been degassed by being stirred and mixed in a vacuum was then poured into this funnel  199  so that the interior of the potting block  190  was filled with resin.  
      In this state, after the resin was cured by being kept at room temperature for 16 hours, the potting block  190  was disassembled into four pieces, and a fiber array body made of polycarbonate hollow fibers having the configuration shown in  FIG. 35  (i.e., having 30 rows by 30 layers) was obtained in which gaps between the polycarbonate hollow fibers were filled with polyurethane resin, and whose cross-sectional dimensions were 20 mm×20 mm×length of 80 mm, and in which organism related substance was fixed to the interior walls.  
      (2) Fixing of Organism Related Substance in A Hollow Fiber Array in which Organism Related Substance has not been Fixed  
      Probe A and probe B that were synthesized in Reference example 1 were added to the solvent B prepared in Reference example 3, and a probe A aqueous solution in which probe A was contained in a concentration of 0.5 nmol/L and a probe B aqueous solution in which probe B was contained in a concentration of 0.5 nmol/L were prepared.  
      Next, all of the ends at one end of the polycarbonate hollow fibers in portions of the obtained fiber array body that had not been fixed by resin were bundled together, and the bundled portion was bound using a rubber band. A portion slightly on the distal end side of the bound portion was then cut. These cut ends were then immersed in a cylindrical container having an internal diameter of 15 mm and a height of 30 mm and that was approximately ⅓ rd  full of the same urethane resin solution that was used previously to fix the fibers together. The urethane resin was then cured so that the polycarbonate hollow fibers were sealed.  
      The other ends of the polycarbonate hollow fibers were separated in alternating layers so that, out of all the layers, two groups made up of 15 fibers by 30 layers were formed. The distal ends of each bundle of 450 fibers was then inserted respectively into containers containing the probe A aqueous solution and the probe B aqueous solution.  
      Next, the fiber array bodies having the ends on one side thereof sealed and having the ends on the other side thereof inserted into containers containing the probe A aqueous solution or the probe B aqueous solution were placed as they were inside a thermal chamber and the interior of the chamber was held under reduced pressure for 5 minutes. Thereafter, nitrogen gas was gradually introduced into the chamber and the chamber was restored to normal pressure. As a result, the probe A aqueous solution and the probe B aqueous solution were drawn into the interior of the hollow fibers. A polymerization reaction was then conducted using a method in which the chamber that was full of nitrogen gas at normal pressure was then heated for 3 hours at a set temperature of 70° C., and the heating was then stopped and the chamber was left at room temperature.  
      As a result, a polycarbonate hollow fiber array body was obtained that held inside it a gel in which the probe A and probe B, which are organism related substance, were fixed.  
      This fiber array body was then sliced into thin pieces having a thickness of 0.5 mm and 140 organism related substance fixed microarrays were obtained.  
     INDUSTRIAL APPLICABILITY  
      As has been described above, by using the fiber array device of the present invention, it is possible to array fibers at a high density accurately in an extremely short period of time. Moreover, according to the present invention, it is also possible to prevent errors when arraying fibers unlike when a conventional method is used in which fibers are arrayed by being inserted into holes in a jig.  
      Accordingly, according to the present invention, by efficiently manufacturing fiber array bodies of fibers in which organism related substance has been fixed, and then slicing these into thin pieces in a direction intersecting the direction of the fibers, it is possible to easily produce in mass organism related substance fixed microarrays in which the type and quantity of a specific organism related substance can be detected in a sample.  
      Moreover, by using the fiber array jig of the present invention, fibers can be efficiently arrayed three-dimensionally at a high density and with a high degree of precision. Moreover, fiber array bodies in which three-dimensionally arrayed fibers are fixed by resin can be mass produced for industry.  
      Namely, if the fiber array jig of the present invention is used, time and energy are not consumed by the task of inserting fibers one by one through holes formed in a jig, as is the case conventionally. Moreover, because it is not necessary to guide the fibers being inserted to the holes using forceps or the like, the problem of fibers that have already being inserted into adjacent holes obstructing the operation of inserting fibers using forceps does not arise. In addition, according to the present invention, because the operation is not one of inserting the fibers into holes, but of arraying them in the concave rows, even if the outer diameter of the fibers is narrow and they have low rigidity, they can be arrayed easily so that a greater degree of density in the array of the fibers becomes possible.  
      Furthermore, when using the fiber array jig of the present invention, the work involved in the fiber array step can be divided so that, from this viewpoint as well, the productivity of the fiber array body is improved.  
      Accordingly, by using the fiber array jig of the present invention to manufacture fiber array bodies of fibers in which organism related substance such as nucleic acids, proteins, and polysaccharides and the like has been fixed, and then slicing these into thin pieces in a direction intersecting the direction of the fibers, it is possible to easily produce in mass organism related substance fixed microarrays in which the type and quantity of a specific organism related substance can be detected in a sample.  
      [Array Table] 
     
         
         
           
              As per attached sheet 
 
 [Array table free text]
 
              Array number 1: Synthesized DNA  
              Array number 2: Synthesized DNA