Patent Publication Number: US-2023152136-A1

Title: Determining fluid flow across rotary pump

Description:
FIELD 
     Systems, devices, and methods are provided for sensing the flow of liquid within a device in which liquid flows, and particularly in connection with a pump for active transport of the liquid. Parameters such as current drawn, pressure, and temperature can be used to accurately and precisely measure fluid flow in a contactless manner. A model can be used to determine the fluid flow using the measured current drawn by the pump, inlet pressure, outlet pressure, pump rotational speed, and fluid density as independent variables. 
     BACKGROUND 
     Conventional devices transporting fluid regulate an amount of liquid that is held and moved for proper functioning of the device. Conventional approaches require calculating flow rates using volumetric or sensor control. In medical applications, the conventional devices administer fluids to patients and regulate how much and how quickly the fluids are delivered using contact measurements such as balance chambers or non-contact measurements such as ultrasonic time-in-transient measurements. Devices that involve admixture of different components to generate a desired result also regulate an amount of each liquid component. Conventional fluid transport mechanisms often use volumetric control as part of the pump mechanism to monitor the flow rate across the pump. Usually, volumetric control uses two identical chambers that are each divided in half by a flexible membrane wherein the system has an inlet and outlet. However, each chamber is a source of error in volumetric control and increases the potential for fluid contamination. Another approach uses load cells to measure weight changes of a fluid container. However, this method is limited to net flow. Another conventional method for fluid regulation relies on counting the rotations of a rotary pump to determine an amount of fluid being pumped. However, the conventional systems and methods using rotary pumps are often inaccurate or imprecise. The problem is exacerbated in medical devices that mix fluid components requiring a high degree of accuracy and precision. Moreover, certain applications require contactless measurement of fluid rates to avoid contamination of medical fluid or to support measurement of hazardous or chemical fluids that might be used to clean or disinfect a medical device. Some of the known devices use non-intrusive sensors such as ultrasonic or optical sensors. However, the known non-intrusive sensors are specific to, and dependent on the specific properties of the fluid being transported, and often cannot reliably sense the movement of fluid in all cases. This can be problematic where admixtures of different fluid components are pumped and mixed in a medical fluid. 
     As such, there is a need for systems, methods, and components that can reliably measure flow rates with appropriate accuracy and precision. The need also includes obtaining measurement using contactless systems, methods, and components. The need still further includes systems, methods, and components that can use a parameter such as pump speed in conjunction with other data gathered from non-intrusive sensors already available within fluid sensing methodology to determine the fluid flow accurately and precisely across a pump. The need includes accurately and precisely monitoring the fluid flow across the rotatory pump of a fluid transport system. The need extends to systems, components, and methods for obtaining additional parameters such as pressure, power consumption, and fluid density to model the fluid flow. The need includes a non-contact flow sensing methodology. The need still includes non-contact systems, methods, and components that can determine fluid flow rates of chemical or hazardous liquid. The need also includes systems, methods, and components having high safety and that can determine the mechanical or electrical load on a pump or uneven loading in the system. 
     SUMMARY OF THE INVENTION 
     The problem to be solved is to monitor the fluid flow accurately and precisely without contacting the measured fluid. The solution is to model the fluid flow using the measured current drawn by the pump, inlet pressure, outlet pressure, pump rotational speed, and fluid density as independent variables and using the model to obtain the flow rate. 
     The first aspect of the invention relates to a system for fluid flow. In any embodiment, the system can include a rotary pump; an inflow line and an outflow line in fluid communication with the rotary pump; an inlet pressure sensor at the inflow line; an outlet pressure sensor at the outflow line; a current sensor measuring the current drawn by the rotary pump; and a circuit calculating fluid flow rate through the system based on a density value for a fluid pumping through the system, rotational speed of the rotary pump, inlet pressure at the inflow line, outlet pressure at the outflow line, and current drawn by the rotary pump. 
     In any embodiment, the system can further include a temperature sensor measuring a temperature of the fluid pumping through the system, the density value for the fluid determined from the measured temperature. 
     In any embodiment, the inlet pressure sensor, the outlet pressure sensor, and the temperature sensor can each be non-intrusive sensors. 
     In any embodiment, the fluid can be peritoneal dialysis fluid. The density value for the liquid can be a known value for the density of peritoneal dialysis fluid at the measured temperature. 
     In any embodiment, the rotary pump can include a driver controlling the rotational speed of the rotary pump, the driver communicating the rotational speed of the rotary pump to the circuit calculating the liquid flow rate through the system. 
     In any embodiment, the circuit can determine a resistance for the rotary pump based on the rotational speed of the rotary pump and the current drawn by the rotary pump, the determined resistance relating a known voltage of the rotary pump to the drawn current. 
     In any embodiment, the circuit can relate fluid flow, Q, to an area A within the inflow line and a velocity v of fluid flow within the inflow line according to the equation: Q=A*v. 
     In any embodiment, the circuit can relate fluid flow, Q, to an area A within the outflow line and a velocity v of fluid flow within the outflow line according to the equation: Q=A*v. 
     In any embodiment, the circuit can relate the inlet pressure, p o , the outlet pressure, p i , and the fluid density value, ρ, according to the equation: v i   2 /2+g*h i +p i /ρ=v o   2 /2+g*h o +p o /ρ; where v i  is the velocity of fluid flow within the inflow line, v o  is the velocity of flow within the outflow line, g is the acceleration due to gravity, h i  is the height of the inflow line, and h o  is the height of the outflow line. 
     The features disclosed as being part of the first aspect of the invention can be in the first aspect of the invention, either alone or in combination, or follow any arrangement or permutation of any one or more of the described elements. Similarly, any features disclosed as being part of the first aspect of the invention can be in the second aspect of the invention described below, either alone or in combination, or follow any arrangement or permutation of any one or more of the described elements. 
     The second aspect of the invention relates to a method for determining fluid flow across a rotary pump. In any embodiment, the method can include the step of calculating a fluid flow rate based on a rotational speed of the rotary pump, a measured pressure difference between a fluid intake and fluid discharge across the rotary pump, a determined density value for the fluid, and a measured current drawn by the rotary pump. 
     In any embodiment, the method can further include the steps of calculating a pressure difference between the fluid inflow line and the fluid outflow line based on a measured suction pressure at a fluid inflow line in fluid communication with the rotary pump and a discharge pressure at a fluid outflow line in fluid communication with the rotary pump. 
     In any embodiment, the method can further include the steps of measuring the current, I, drawn by the rotary pump; comparing the drawn current and a known voltage, V, of the rotary pump to the rotational speed of the rotary pump to determine a resistance, R, for the rotary pump according to the following equation: V=I*R; wherein the fluid flow is calculated based on the determined resistance. 
     In any embodiment, the method can further include the step of displaying the calculated fluid flow rate. 
     In any embodiment, the density value for fluid moving across the rotary pump can be determined by measuring a temperature for the fluid and calculating the density based on the measured temperature. 
     In any embodiment, the rotational speed of the rotary pump can be measured by a driver regulating the speed of the rotary pump. 
     In any embodiment, calculating the fluid flow, Q, can include relating to an area A within the inflow line and a velocity v of fluid flow within the inflow line according to the equation: Q=A*v. 
     In any embodiment, calculating the fluid flow, Q, can include relating to an area A within the outflow line and a velocity v of fluid flow within the outflow line according to the equation: Q=A*v. 
     In any embodiment, the method can include the step of relating the inlet pressure, p o , the outlet pressure, p i , and the fluid density value, ρ, according to the equation: v i   2 /2+g*h i +p i /ρ=v o   2 /2+g*h o +p o /ρ; where v i  is the velocity of fluid flow within the inflow line, v o  is the velocity of flow within the outflow line, g is the acceleration due to gravity, h i is the height of the inflow line, and h o  is the height of the outflow line. 
     In any embodiment, the method can further include the steps of applying current drawn by the rotary pump and temperature of the fluid as independent variables in modeling the fluid flow across the pump; and calculating the fluid flow based on the modeling. 
     In any embodiment, measured suction pressure at an inflow line and measured discharge pressure at an outflow line can also be independent variables in modeling the fluid flow across the pump. 
     In any embodiment, the rotational speed of the rotary pump can also be an independent variable in modeling the fluid flow across the pump. 
     The features disclosed as being part of the second aspect of the invention can be in the second aspect of the invention, either alone or in combination, or follow any arrangement or permutation of any one or more of the described elements. Similarly, any features disclosed as being part of the second aspect of the invention can be in the first, aspect of the invention described above, either alone or in combination, or follow any arrangement or permutation of any one or more of the described elements. 
    
    
     
       BRIEF DESCRIPTION OF THE DRAWINGS 
         FIG.  1    is a cross-sectional view of a portion of a fluid transport system. 
         FIG.  2    is a diagram of electrical components of a fluid flow sensing system. 
         FIG.  3    is a cross-sectional view of a rotary pump within a fluid transport system. 
         FIG.  4    is an illustration of a design of experiments (DOE) model for fluid flow across a rotary pump. 
         FIG.  5    is a flow chart showing steps for calculating fluid flow rate within a fluid transport system. 
         FIG.  6    is a cross-sectional view of a portion of a fluid transport system having vanes. 
         FIG.  7    is a cross-sectional view of a portion of a fluid transport system having rotating pumping compartments. 
     
    
    
     DETAILED DESCRIPTION 
     Unless defined otherwise, all technical and scientific terms used have the same meaning as commonly understood by one of ordinary skill in the art. 
     The articles “a” and “an” are used to refer to one to over one (i.e., to at least one) of the grammatical object of the article. For example, “an element” means one element or over one element. 
     To “associate” means to identify one piece of information as related to a second piece of information. 
     To “calculate,” “calculating,” and the like means to determine a particular value by applying one or more equations and/or functions to one or more values. 
     A “circuit” is a component of a system that is in electrical communication with other components. A circuit can be a processor, controller, or other electronic or digital component that sends, receives, and/or processes electronic data, instructions, and/or information. 
     The terms “communication,” “communicate,” “communicating,” and the like can refer to the ability to transmit electronic data, instructions, information wirelessly, via direct electrical connection, or any other electrical transmission means between one or more components. 
     The terms “compare,” “comparing,” and the like means to determine whether two files or data are the same or different. A difference between the two file or data can be obtained by the comparison. 
     The term “comprising” includes, but is not limited to, whatever follows the word “comprising.” Use of the term indicates the listed elements are required or mandatory but that other elements are optional and may be present. 
     The term “consisting of” includes and is limited to whatever follows the phrase “consisting of.” The phrase indicates the limited elements are required or mandatory and that no other elements may be present. 
     The term “consisting essentially of” includes whatever follows the term “consisting essentially of” and additional elements, structures, acts or features that do not affect the basic operation of the apparatus, structure or method described. 
     A “controller” or “driver” is a device capable of sending signals to manage the operation of one or more devices in a system. A single component, such as a processor, circuit, or other device, may be a controller or driver for more than one component of a system. 
     “Current” is a measure of electricity drawn by a device. Any movement of electrical charge within a system is considered current. 
     A “current sensor” is a device capable of measuring the current flow across any electrical component of a system, either directly or indirectly. Devices that use other quantities of electrical circuits such as resistance, voltage, power, and/or heat to indirectly determine current are also considered current sensors if they calculate and/or report current measurements as part of their regular function. 
     “Density” or “fluid density” is the proportion of a fluid&#39;s mass to volume. The density of a fluid can vary based on other properties of the fluid, such as temperature and pressure. A “density value” is a measurement or calculation of density. 
     The term “device,” as used herein, refers to any device that can authenticate a user or USB authentication device. 
     The term “determining” or to “determine” refers to ascertaining a particular state of a component or system. 
     The term “device” is to be interpreted in the broadest sense and can include anything made for a particular purpose, a contrivance of any type, particularly a mechanical or electrical component or hardware. Some examples of devices can include a medical device such as a dialysis machine, laptop, computer, computer peripherals of any type, computer terminals, portable devices, smart phones, and smart watches. 
     A “dialysis system” is a collection of medical devices used to provide dialysis treatment to one or more patients. 
     The term “execute” means to perform a step or series of steps. 
     The terms “flowing” or to “flow” “refer to the movement of a fluid. 
     A “fluid” is a substance in a liquid and/or gaseous phase. A liquid substance having a combination of gas and liquid phases is a fluid. Notably, a liquid, as used herein, can therefore also have a mixture of gas and liquid phases of matter. 
     A “fluid characteristic” is any sensed characteristic of a fluid, including temperature, pressure, concentration, or any other characteristic. 
     The term “fluid communication” means that two chambers are connected, either directly or indirectly, with or without intervening elements such as valves, membranes, stoppers, or the like, so that fluid flows from one chamber into another. Chambers are in “fluid communication” whether or not the fluid flows in both directions. 
     A “fluid flow path” refers to a pathway through which a fluid, gas, and combinations thereof can travel. 
     An “inflow line” or “fluid inlet” refers to a refers to a conduit or opening through which fluid, gas, and combinations thereof can enter a component or apparatus. 
     “Inlet pressure” is pressure measured at a fluid inlet. 
     A component is “intrusive” if positioned within a chamber for holding or transporting liquid such that the component will come in physical contact with the liquid. 
     The term “medical device” refers to a device used to perform medical treatment or diagnosis of any type. 
     To “measure,” “measuring,” and the like, to determine a quantifiable property of a component or system. The measured or sensed property or parameter can be obtained via a sensor of any type known to those of ordinary skill. 
     A system or method is “non-intrusive” if containing no intrusive components—that is, if every component of the system or used to implement the method is positioned outside of the chambers where liquid is transported and stored so that none of the components come in physical contact with the liquid. 
     An “outflow line” or “fluid outlet” refers to a refers to a conduit or opening through which fluid, gas, and combinations thereof can exit a component or apparatus. 
     “Outlet pressure” or “discharge pressure” is pressure measured at a fluid outlet. 
     The term “peritoneal dialysis fluid” refers to the mixture that is injected into a patient during peritoneal dialysis treatment. When properties of peritoneal dialysis fluid are described herein, such as its dielectric properties and permittivity, they refer to the properties of the fluid before use in treatment. 
     A “peritoneal dialysis system” is a collection of medical devices used to provide peritoneal dialysis treatment to a patient. 
     A “pressure sensor” is a system component that measures the pressure of a fluid at a particular point in the fluid flow path. 
     The term “programmed” can mean a series of instructions that cause a device or system to perform certain steps. 
     A “pump” is a component that applies mechanical force to move fluid. 
     The term “receiving” refers to the process of obtaining electronic information by any means. 
     “Resistance” refers to electrical resistance, defined as the ratio between electric potential and electric current in a circuit element. Resistance is calculated based on measured voltage and current, applying the equations disclosed herein. 
     A “rotary pump” is a pump with one or more rotating elements that can move a fluid along a flow path. 
     “Rotational speed” refers to the rate at which a component or device rotates about a given axis. Rotational speed can be measured in rotations per unit time by establishing when a particular orientation is referred to. 
     A “rotor” is a component of a rotating device, such as a rotary pump, that is designed to rotate relative to other components during normal operation of the device. 
     The term “sending” refers to the process of transmitting electronic information to be received. 
     A “sensor” is a device configured to determine a particular state of a component or system. 
     A “stepper motor” is device that drives a rotor by activating and deactivating a series of stationary electromagnets to exert asymmetrical forces on components of the rotor moves, thereby applying torque to the rotor. 
     “Suction pressure” refers to a negative pressure difference across a fluid path. In one non-limiting example, a pump having an inflow and outflow line can induce a suction pressure on an inflow line in the downstream direction during operation. 
     The term “upstream” refers to a position of a first component in a flow path relative to a second component wherein fluid will pass by the first component prior to the second component during normal operation. The first component can be said to be “upstream” of the second component, while the second component is “downstream” of the first component. 
     Sensors Across Pump 
       FIG.  1    shows a portion of a flow path including a rotary pump  101 . The rotary pump  101  can be positioned in a chamber  102  between a fluid inlet  103  and fluid outlet  104 . During operation, the pump  101  can rotate in a clockwise or counterclockwise direction to push fluid around the chamber  102  and increase fluid speed within the fluid path. As more force is applied to the pump  101  to increase rotational speed, the effect of the pump  101  on the fluid is increased. In one non-limiting embodiment, a shaft (not shown) can be inserted into a receiving molded portion of the pump  101  such that the shaft is not in fluid contact with an inner portion of the pump components of chamber  102 . That way, the inserted shaft can provide rotational force to the internal vanes of the pump  101  while avoiding direct contact and therefore, possible contamination of the interior surfaces of the pump vanes, fluid paths of the fluid inlet  103  and fluid outlet  104 , and interior surfaces in contact with the fluid being pumped of chamber  102 . The rotation speed of a rotary pump is only one of several variables that influence the actual fluid flow rate across the pump. For example, flow path pressures and fluid density can also affect the rate of fluid flow across a rotary pump for a given rotation speed. 
     To determine the pressure differential introduced by the pump  101 , pressure sensor  105  and pressure sensor  106  can be placed in the fluid inlet  103  and fluid outlet  104 , respectively. The pressure sensor  105  and pressure sensor  106  can be intrusive sensors that detect fluid pressure in proportion to the pressure exerted on each of pressure sensor  105  and pressure sensor  106  by the fluid. In some implementations, one or both pressure sensor  105  and pressure sensor  106  may be built into valves (not shown) that can provide additional control over the fluid flow within the fluid paths of the fluid inlet  103  and fluid outlet  104 . As the pressure at the fluid inlet  103  may primarily come from the action of the rotary pump  101 , drawing fluid into the chamber  102 , the inlet sensor  105  can be a suction pressure sensor configured to detect and measure the negative pressure from downstream. Correspondingly, the outlet sensor  106  may be a discharge sensor configured to detect and measure the positive pressure from upstream due to the rotary pump  101  pushing fluid out of the chamber  102 . 
     A temperature sensor  107  can be included within the fluid paths of the fluid inlet  103  and fluid outlet  104  to measure the temperature of the fluid. The temperature sensor  107  may be, for example, a thermocouple or other temperature-sensitive element. Depending on the thermal properties of the fluid and of the walls of the fluid inlet  103 , fluid outlet  104 , and chamber  102 , the temperature sensor  107  may be a non-intrusive sensor placed on any outside wall surface. In other embodiments, the temperature sensor  107  may be placed within a flow path to contact the fluid directly. 
       FIG.  2    is a system diagram showing sensor and controller components in electronic communication. An inlet sensor  105 , outlet sensor  106 , and temperature sensor  107 , can each send signals to a system controller  201 . Each signal may be raw data or may be calibrated measurement data in different configurations of the system. Activation and control of the sensors  105 - 107  may depend on the control of other system components and may be directly or indirectly operated by the system controller  201 . In some implementations, one or more of the inlet sensor  105 , outlet sensor  106 , and temperature sensor  107  may be controlled by other means, such as activating automatically whenever certain changes in the fluid flow of the system are detected. Signals may be sent in response to particular commands, may be sent whenever a certain change is detected, may be sent periodically according to predetermined time intervals, or combinations of the these and other mechanisms for sensor operation as known in the art. 
     The rotary pump  101  may in turn be controlled by a pump driver  202 , which may send control signals to the pump  101  to regulate rotational speed. In some embodiments, the pump driver  202  may include hardware or software components in common with the system controller  201 . The driver  202  can also communicate the pump rotational speed to the system controller  201 . In some embodiments, this speed may represent a setting used by the driver  202 ; in some embodiments, rotational speed may be a measurement obtained by the pump driver  202  according to one or more readings taken by sensors disposed about the pump in communication with the pump driver  202 . 
     A current sensor  203  can send sensor data to the system controller  201  based on measurements taken of components of the system. The current sensor is configured to monitor and return data on the current load drawn to run the rotary pump  101  and can be disposed anywhere within the rotary pump motor and power source to measure and relay this data. 
       FIG.  3    shows a non-limiting embodiment of a rotary pump  300  driven by a motor. In one version, the motor is a stepper motor as defined herein. A rotor  301  includes a vane magnet  302   a,  a vane magnet  302   b,  and a vane magnet  302   c  that provide a basis for driving the rotor  301  within the chamber  303  in a rotational direction as shown. Stationary electromagnet  304   a , electromagnet  304   b,  electromagnet  304   c,  electromagnet  304   d,  and electromagnet  304   e,  can be embedded in the walls of the chamber  303  and positioned to be proximate with each vane magnet  302   a,  a vane magnet  302   b,  and a vane magnet  302   c,  when the rotor  301  reaches a specified angular orientation with respect to the chamber  303 . 
     Each of the electromagnet  304   a,  electromagnet  304   b,  electromagnet  304   c , electromagnet  304   d,  and electromagnet  304   e,  can be switched on or off to impel the rotor  301  to rotate in the intended direction based on the positions of the vane magnet  302   a,  a vane magnet  302   b,  and a vane magnet  302   c,  which are known using Hall effect circuits  305   a  and  305   b.  The known position and distance of the Hall effect circuits, which report the proximity of a vane magnet, allow for the pump driver to determine the speed and relative rotational position of the rotor  301  and operate the electromagnet  304   a,  electromagnet  304   b,  electromagnet  304   c , electromagnet  304   d,  and electromagnet  304   e  in the appropriate sequence. 
       FIG.  3    illustrates a design of experiments (DOE) model  400  using the sensor data collected in the system as independent variables. Inlet pressure p i  ( 401 ), outlet pressure p o  ( 402 ), rotational speed v pump  ( 403 ), current draw I pump  ( 404 ), and fluid temperature T fluid  ( 405 ) are each measured by sensors as described above. Each variable can act as an input to the system  406 , which may respond nonlinearly when producing the dependent variable Q flow . In some embodiments, a slow or intrusive method of accurately measuring the fluid flow rate of the system may be used when carrying out the experiments that would not be suitable when using the system  405  for an intended purpose. 
     Under controlled conditions, each of the variables  401 - 405  is adjusted, alone and in combination with the others, to create a fit function f flow( )  that models the effects of the independent variables on the system&#39;s flow rate. The resulting fit function, which may be any analytical function or set of functions as known in the art, can then be applied to calculate the flow rate when the independent variables are measured as described herein. 
     The pressure variables p o  and p i  are related according to Bernoulli&#39;s equation to the density of the fluid, ρ, as follows: 
         v   i   2 /2 +g*h   i   +p   i   /ρ=v   o   2 /2 +g*h   o   +p   o /ρ
 
     where v i  and v o  are the fluid inflow and outflow speeds, respectively, g is acceleration due to gravity, and h is the elevation at each point.
 
Fluid density is related to the measured independent variable, T fluid , according to a reference density ρ 0  defined at a set temperature T 0  and a volumetric temperature coefficient β that is characteristic for each fluid. The density is then given by the equation:
 
       ρ=ρ 0 /(1+β( T   fluid   −T   0 )
 
     The torque necessary for the pump rotor to rotate at a particular speed will depend on the drag offered by the fluid in which the rotor moves, which in turn will vary based on the flow speed. Drag on the rotor will translate into resistance on the pump circuit, which is proportional to current drawn as follows: 
     
       
      
       V 
       pump 
       =I 
       pump 
       *R 
       pump  
      
     
     where V pump  and R pump  relate the voltage and resistance of the pump driver circuit to the current I pump  of the circuit that is measured as described herein. 
       FIG.  5    illustrates a process in which the flow across a rotary pump is calculated using the components described above. The inlet and outlet pressures can both be monitored (steps  501  and  502 ) and used to determine a pressure differential (step  503 ). This pressure differential may be determined based on matching measurements between inlet and outlet sensors that take into account the two sensors may not be precisely synchronized. For example, where one sensor has not measured data within a given interval, data from the other sensor may be discarded. Alternatively, a signal may be sent to a sensor to collect further measurements whenever corresponding measurements are received that might otherwise not be used. 
     Subtracting the pressure at the inlet sensor from the pressure at the outlet sensor is the most straightforward way of determining the differential. However, one of ordinary skill in the art will recognize that other methods of using the two data points may be used. For example, data from one or both sensors may be adjusted before it is used to determine a pressure differential. A raw inlet pressure measurement p i  and outlet pressure measurement p o  might be first adjusted using fit formulas f inlet  and f outlet  as follows: 
         p*   inlet   =f   inlet ( p   i ) 
         p*   outlet   =f   inlet ( p   o ) 
     
       
      
       Δp=p* 
       outlet 
       −p* 
       inlet  
      
     
     The fit formulas may, for example, be linear, polynomial, quadratic, or any analytic formula determined by experimentation with pressure sensors the rotary pump. 
     At step  504 , the fluid temperature is monitored, which is then used to determine the density of the fluid (step  505 ). Density values may, in some embodiments, be calculated using a formula that is based on knowing the fluid for which the system is used. For example, when a pump is used to transport water for filtration and use in medical treatment, the known density of water at different temperatures can be used to determine the density of water based on measured temperature in the flow system. When a pump is used to transport peritoneal dialysis fluid, additional properties of the fluid, such as the solute concentration for different additives, may also be needed to accurately calculate fluid density. These properties may be measured or may be received from controller elements associated with the preparation and/or administration of the fluid. In different embodiments, controller elements associated with preparation and/or administration of the fluid may be integrated with, or separate from, controller elements associated with monitoring and controlling the rotary pump as described herein. 
     At step  506 , the system receives the speed of the rotary pump, which may come from the pump driver or an analogous component. In different embodiments, this speed may reflect a measurement of the pump rotor or may instead reflect a setting for what speed a command to the pump indicates it should move at. Depending on the measurement fidelity, and/or the accuracy of the pump driver compared to its setting, the received value may be calibrated before it is used. 
     At step  507 , the current used by the pump is monitored. This reflects the load required by the stepper motor or other device driving the rotary pump to maintain the pump at the regulated speed, with a higher load representing greater resistance by the fluid. 
     At step  508 , if any of the given settings are outside established limits, the system may take corrective action (step  509 ). This may be in the form of an automated adjustment, an alert to user or other system, or a temporary halt to the pump or some other fluid flow components. The action taken can depend on the number of parameters exceeded, the specific parameter being monitored, and the scalar difference. 
     If all the reported values fall within acceptable limits, then the system calculates the fluid flow across the pump (step  510 ). Rather than a simple linear or polynomial equation, this calculation may involve the application of different analytic functions depending on where each of the measured and calculated values fall. We can generalize the equation to a four-parameter analytic function as follows: 
         Q   flow   =f   flow (Δρ, δ fluid   , v   pump   , I   pump )
 
     where ρ fluid  is the fluid density, v pump  is the angular velocity of the pump, and I pump  is the current load of the pump. The resulting value is the volumetric flow rate for the fluid flow path across the pump. 
       FIG.  6    illustrates another example of a rotary pump  601  in a chamber  602  for which conventional sensors can non-intrusively and accurately calculate fluid flow. Here, the pump  601  includes eight vanes  601 ′ that extend most of the distance between the center of the chamber  602  and the chamber walls. Fluid inlet  603  and fluid outlet  604  each include a pressure sensor  605  and  606  respectively, similar what is described above. 
     A temperature sensor  607  can be placed at the fluid outlet  604 . The fluid outlet  604  may be found, experimentally, to provide a more accurate temperature measurement for the purposes of calculating an accurate fluid flow, or the position may be more convenient for placing the sensor  607  for mechanical reasons. A barrier  608  may also be present within the chamber  602  that can be passed by the vanes  601 ′ but reduces the flow of fluid in the upper sector of the chamber  602  between the inlet  603  and outlet  604 . This can help prevent undesired backflow that might otherwise be expected as part of the rotational movement of the pump rotor. 
       FIG.  7    illustrates a rotary pump having two rotors  701   a  and  701   b  which rotate in an interlocking manner within a chamber  702  to promote fluid flow across the center of the chamber  702  as shown. Here, the fluid inlet  703  and fluid outlet  704  are located at directly opposite sides of the chamber  702 . In some embodiments, the driver associated with the action of this pump may coordinate the rotations of the rotors  701   a  and  701   b  to avoid interference between them. An inlet pressure sensor  705  is disposed at the fluid inlet and an outlet pressure sensor  706  at the fluid outlet. The temperature sensor  707  is adjacent the wall of the chamber  702  itself, which may in some embodiments allow for a more useful temperature measurement for calculating the fluid flow rate. 
     The shape of the chamber  702  is shown to be roughly elliptical, but the shape and the shape of the rotors  701   a  and  702   b  can vary according to the desired flow characteristics of the pump. In some embodiments, the shape and size of the pump chamber and the rotors, as well as the number and positions of the rotors, may be additional independent variables that are investigated in generating accurate calculation models for fluid flow. 
     One skilled in the art will understand that various combinations and/or modifications and variations can be made in the described systems and methods depending upon the specific needs for operation. Various aspects disclosed herein may be combined in different combinations than the combinations specifically presented in the description and accompanying drawings. Moreover, features illustrated or described as being part of an aspect of the disclosure may be used in the aspect of the disclosure, either alone or in combination, or follow a preferred arrangement of one or more of the described elements. Depending on the example, certain acts or events of any of the processes or methods described herein may be performed in a different sequence, may be added, merged, or left out altogether (e.g., certain described acts or events may not be necessary to carry out the techniques). In addition, while certain aspects of this disclosure are described as performed by a single module or unit for purposes of clarity, the techniques of this disclosure may be performed by a combination of units or modules associated with, for example, a device.