Patent Publication Number: US-2022218775-A1

Title: Herbal products and methods for tetrahydrocannabinol (thc) detoxification

Description:
FIELD OF THE INVENTION 
     The present invention relates to herbal teas and drinks and methods of using same for purging toxins in the bloodstream and urine of a subject. Such toxins include tetrahydrocannabinol (THC) and its detectable metabolites. 
     BACKGROUND OF THE INVENTION 
     Regular drug testing is a reality for many Americans. Numerous companies continue to check their employees for drugs such as marijuana, despite the fact that it is now legal in the majority of states. And, unfortunately, even if one lives in a state where recreational use is legal, a positive drug test could lead to being fired from a job. 
     Routine drug tests also continue to be part of legal system, often being required to monitor individuals on probation or as part of a judicial sentence. 
     More frequently, individuals consider or utilize home drug testing in anticipation of an upcoming drug screening, especially if they are unsure whether they will have issues with recent recreational use showing a positive result. 
     Home drug tests have become widely available from both local drug stores such as CVS and Walgreens, and online retailers. Kits are available for testing saliva, urine, and hair, although urine tests are by far the most common. These kits usually include a collection cup, the test itself (a strip, card, or cassette), and instructions for use. Some kits also contain shipping containers so that one can send a sample off to a laboratory for further testing if necessary. The laboratory will typically provide more detailed and accurate results. 
     Home kits (and even most employer-used kits) are generally qualitative, i.e. they indicate whether a particular substance is in an individual&#39;s system, and not exactly how much of any given substance is present, i.e. they are not quantitative. This is important because passing a drug screening (or not) will depend on the detectable cut-off levels for that particular drug. For example, for THC, the typical cut-off is 50 ng/ml. 
     If a home drug test is positive, and there is an official screening coming up, there are still various ways that individuals can attempt to increase their chances of passing. For example, other than using a synthetic or powdered urine to cheat the test, common methods include: i) stop using substances well before the anticipated drug test; ii) postponement of the official test if possible; iii) ingestion of extra water prior to testing in order to attempt to dilute the urine while simultaneously taking a vitamin B supplement to retain a natural yellow urine color; iv) providing a urine sample later in the day to avoid a more concentrated sample early in the morning; v) take the urine sample mid-stream; vi) stopping exercise activities at least 24 hours prior to the test as exercise releases THC metabolites from fat cells; vii) reducing calorie intake to reduce body fat; and, viii) utilizing a home detoxification product. However, home detoxification products are variable in terms of their effectiveness. 
       Momordica charantia  is a tropical and subtropical vine of the family Cucurbitaceae, widely grown in Asia, Africa, the Caribbean, and the southern regions of the United States. It has a long history of use as a hypoglycemic agent, however, different parts of the plant are used medicinally to treat many disorders conditions in humans including: high blood pressure, diabetes (hyperglycemia), fever, skin fungal infections, gastrointestinal cramps, psoriasis, hyperlipidemia, hemorrhoids, glaucoma, infertility and gynecological conditions, viral infections and certain cancers. See for example: Hudson, (2012) “Nutrient Profile: Bitter Melon ( Momordica charantia ),” Natural Medicine Journal, vol. 4. 
     The four parts of the  Momordica charantia  plant include the vine, leaves, yellow flowers, and bitter melon fruit. The plant contains several substances that likely contribute to its effectiveness as a medicinal product. These include various alkaloids, glycosides and peptides. 
     The  Momordica charantia  plant also contains several unique compounds that are thought to possess pharmacological properties: 
     Cucurbitin belongs to a family of structurally diverse triterpenes found in the members of Cucurbitaceae and several other plant families that are known to have immense pharmacological potential. See Kaushik et al., (2015) “Cucurbitacins—An Insight into Medicinal Leads from Nature,” Pharmacogn Rev. 9(17): pp. 12-18. Charantin is a natural steroidal glycoside present in the fruits of the plant and has been reported to possess potential hypoglycemic or anti-diabetic activity. See Nagappan et al., (2018) “Charantin: A Neglected Antidiabetic Compound from  Momordica Charantia  L.,” Int. J. Pharm. Sci. Rev. Res., 51(2), pp 35-40. Cucurbitacin, contained abundantly in  Momordica charantia , is a bitter tasting compound that has been isolated from other members of the family Cucurbitaceae, such as cucumber and melon. Cucurbitacin exhibits anti-cancer activity and is also used for the treatment of hepatic disease in traditional Chinese medicine. Cucurbitacin has a broad range of pharmacological properties including purgative, hepatoprotective, antifungal, anti-inflammatory, cytotoxic, and antineoplastic activities. See Hudson 2012. 
     Momordin is one of several saponins derived from oleanolic acid and is a triterpenoid. 
     Momorcharins are a type-I ribosome inactivating protein that found in  Momordica charantia  and has shown to be effective against a broad range of human viruses as well as having antitumor activities. In addition, the  Momordica charantia  plant also contains several proteins which can serve as a fuel source. Further, the melon has been identified as the source of many of the above compounds. The melon&#39;s traditional use has included its use in gynecological disorders and for the treatment of infertility. 
       Momordica charantia  is also known to have various purgative properties. 
     What is needed is a home detoxification product, preferably with substantial purgative properties that is effective in clearing an individual&#39;s system or urine of substances that can negatively impact an official or employment-related drug screening test. 
     SUMMARY OF THE INVENTION 
     The present application provides a THC detoxification product comprising an Herbal THC Detoxification Blend composed of a decoction of  Momordica charantia  blended into an herbal drink, or other beverage that when ingested within 24 hours of drug screening test, will eliminate all traceable THC metabolites for an individual&#39;s system such that a urine test will show up as negative. 
     In some embodiments, the Herbal THC Detoxification Blend includes additional ingredients such as herbs and other natural products. These additional ingredients have health benefits on their own and provide a way to cleanse the bloodstream of THC, boost endurance and stamina, allowing THC users to have the cognitive function to perform daily life duties. 
     Embodiments of the current invention include carefully chosen blend of herbs that work together to detoxify the body of harmful toxins, therefore increasing energy, vitality, and stamina. Additional benefits include increased mental awareness and focus, increased endurance, weight loss, cold and flu relief. 
     Other embodiments of the current invention include methods of preparing the Herbal THC Detoxification Blend. Still other embodiments are drawn to methods of using the Herbal THC Detoxification Blend in order to clear an individual&#39;s system of detectable THC metabolites. 
     More specifically, an embodiment of the current invention includes a composition for the removing tetrahydrocannabinol or its metabolites from an individual&#39;s bloodstream and urine comprising an aqueous decoction of the plant  Momordica charantia,    
     In another embodiment, the composition for the removing tetrahydrocannabinol or its metabolites from an individual&#39;s bloodstream and urine comprises a solution made from the  Momordica charantia  which has been dried and ground. 
     In other embodiments of the invention the compositions made from the  Momordica charantia  plant further comprise water and one or more herbs or other natural products. 
     In still other embodiments of the current invention, the compositions made from the  Momordica charantia  plant include one or more of an herb or other natural products is selected from the group consisting of the fruit of the  Momordica charantia  plant, elder flower, dandelion root, green tea leaves, lemon balm, lemon peel, and crystalized ginger root. 
     In any of the embodiments of the current invention, the compositions can include a sweetener. 
     Another embodiment of the current invention is drawn to a method for removing tetrahydrocannabinol or its metabolites from an individual&#39;s bloodstream and urine comprising ingesting any one of the  Momordica charantia  plant compositions described herein. 
     In any embodiment of the current invention, the amount of the  Momordica charantia  plant composition ingested is based upon the body weight of the individual. 
     In any embodiment of the current invention, the  Momordica charantia  plant composition is ingested one or more times over a period of four hours. 
     In yet other embodiments of the current invention, the  Momordica charantia  plant composition is ingested one or more times within a 24 to 48 hour period or until THC or its detectable metabolites are not detected in the urine or other sample form the individual. 
     In any of the methods of the current invention, the efficacy for removing tetrahydrocannabinol or its metabolites from an individual&#39;s bloodstream and urine is monitored using a home drug testing kit. 
     The foregoing has outlined rather broadly the features and technical advantages of the present disclosure in order that the detailed description that follows may be better understood. Additional features and advantages of the disclosure will be described hereinafter that form the subject of the claims of this application. It should be appreciated by those skilled in the art that the conception and the specific embodiments disclosed may be readily utilized as a basis for modifying or designing other embodiments for carrying out the same purposes of the present disclosure. It should also be realized by those skilled in the art that such equivalent embodiments do not depart from the spirit and scope of the disclosure as set forth in the appended claims. 
    
    
     DETAILED DESCRIPTION OF THE INVENTION 
     The current invention is drawn to an Herbal THC Detoxification Blend that can be incorporated into a tea or other suitable beverage. The current invention includes a first step of decocting the fresh  Momordica charantia  plant including the vines, leaves, whole fruit to make an an extraction which possesses purgative properties. Various other ingredients are also added, for example, lemon peel which, among other things, balances the flavor of the brewed decoction. 
     As a second step of the current invention, blend of herbs are added to the  Momordica charantia  decoction in order to accomplish, among other things, a boost of the functionality of the detoxification which in addition to cleansing THC and detectable metabolites from the bloodstream and urine, can increase mental awareness and focus, increased endurance, relieving sinusitis, cold relief and much more. 
     Various embodiments of the invention also include the bottling the initial brewed blend of the  Momordica charantia  plant with sweeteners or alternatively, packaging individual servings of dried herbal blend as a loose leaf tea blend using sachets or tea bags 
     Aqueous Decoction of  Momordica charantia    
     In a non-limiting example of the current invention, an aqueous decoction of the  Momordica charantia  is made. The entire  Momordica charantia  plant is used (typically about 14 total grams. The yellow flowers are not used. 
     As a person of skill in the art would be aware, “decoction” is a method of extraction by boiling herbal or plant material to dissolve the chemicals of the material, which may include stems, roots, bark and rhizomes. 
     Decoction of the  Momordica charantia  to make the Herbal THC Detoxification Blend involves first separating fresh or previously frozen plants into approximate 14-20 g bunches in which all fruit connected to vines are removed and then placed into large cloth bags. The plants in the bags are then mashed in the bags. The bitter melon fruit are then added back to the bag. The bags are then boiled in approximately 1800 mL distilled or spring water for about 15 min. The inventor has found that the boiling allows for the extraction of oils, volatile organic compounds and various chemical substances from the plant. 
     The resulting solution is strained to remove the plant and lemon slices and any other remaining particles. For example, a sliced whole lemon can be added for taste. The resulting mixture is and strained 5-10 times to remove any excess particles. Further, once the decoction solution is strained, other ingredients can be added. As a non-limiting example, a sweetener such as  stevia  is added to improve the taste of the decoction. It is contemplated that the amount and type of sweetener can be varied according to individual preferences. The resulting decoction solution is typically 1500 ml. This typically yields three 500 ml detoxification doses. 
     Preparation of the Herbal THC Detoxification Blend 
     The Herbal THC Detoxification Blend can be made either from brewing the Dried  Momordica charantia  plant described above or directly from the Aqueous Decoction solution. 
     Importantly, the inventor has discovered that the inclusion of one or more additional herbs or other natural ingredients adds to the purgative benefits and provides additional health benefits in addition to improving taste and drinkability to the Herbal THC Detoxification Blend. 
     Non-limiting examples are described below: 
     
       
         
           
               
               
               
             
               
                   
               
               
                   
                   
                 Benefit to the Herbal 
               
               
                 Ingredient 
                 Traditional Use 
                 Blend* 
               
               
                   
               
             
            
               
                 Elder Flower 
                 used for swollen sinuses 
                 Increases urine  
               
               
                   
                 (sinusitis), cold and flu, 
                 production 
               
               
                   
                 bronchitis, diabetes, and 
                   
               
               
                   
                 constipation 
                   
               
               
                 Dandelion  
                 promotes healthy digestion, 
                 Natural detoxification 
               
               
                 Root 
                 liver function, noted for its 
                 substance 
               
               
                   
                 effectiveness to assist with 
                   
               
               
                   
                 hormone imbalance, stomach 
                   
               
               
                   
                 upset, fever and flu 
                   
               
               
                 Green tea  
                 Mood elevation, calmness, 
                 Improves taste; provides  
               
               
                 leaves 
                 mental awareness and focus, 
                 a pleasant vehicle 
               
               
                   
                 increases metabolism and 
                   
               
               
                   
                 helps with weight loss, 
                   
               
               
                   
                 reduces cholesterol, promotes 
                   
               
               
                   
                 immune health, may have 
                   
               
               
                   
                 cancer prevention properties. 
                   
               
               
                 Lemon Balm 
                 Traditionally used to improve 
                 Calming effect;  
               
               
                   
                 mood and cognitive function,  
                 improves taste 
               
               
                   
                 helps relieve stress, reduces 
                   
               
               
                   
                 anxiety, eases insomnia and 
                   
               
               
                   
                 sleep disorders, relive 
                   
               
               
                   
                 indigestion, minimize 
                   
               
               
                   
                 menstrual cramps 
                   
               
               
                 Ginger Root  
                 natural oil (gingerol); 
                 Flavoring 
               
               
                 (crystalized) 
                 antioxidant and anti- 
                   
               
               
                   
                 inflammatory properties; 
                   
               
               
                   
                 promotes digestion, reduces 
                   
               
               
                   
                 nausea supports immune 
                   
               
               
                   
                 function. 
                   
               
               
                 Lemon Peel 
                 D-limonene and Vitamin C 
                 Flavoring 
               
               
                   
                 thought to have antibacterial, 
                   
               
               
                   
                 antimicrobial, antifungal, 
                   
               
               
                   
                 antioxidant properties, may 
                   
               
               
                   
                 have anticancer properties; 
                   
               
               
                   
                 reduces risk of heart disease, 
                   
               
               
                   
                 D-limonene thought to lower 
                   
               
               
                   
                 blood sugar, triglyceride, and 
                   
               
               
                   
                 LDL cholesterol levels, while 
                   
               
               
                   
                 increasing HDL cholesterol 
               
               
                   
               
            
           
         
       
     
     See for example: Ulbricht et al., (2014) “An Evidence-Based Systematic Review of Elderberry and Elderflower ( Sambucus nigra ) by the Natural Standard Research Collaboration” J. Dietary Supplements, 11(1): pp. 80-120; Jedrejek et al., (2019) “Comparative phytochemical, cytotoxicity, antioxidant and haemostatic studies of  Taraxacum officinale  root preparations,” Food Chem Toxicol 26: pp. 233-247; Gunnars, (2020) “Ten Evidence-Based Benefits of Green Tea,” [www.healthline.com/nutrition/top-10evidence-based-healthbenefits-of-green-tea]; Cronkleton, (2019) “Ten Benefits of Lemon Balm and How to Use It,” [www.healthline.com/health/lemon-balm-uses]; Bode et al., (2011) “The Amazing and Mighty Ginger,” In: Benzie et al., eds.  Herbal Medicine: Biomolecular and Clinical Aspects.  2 nd edition , Chapter 7, Boca Raton: CRC Press/Taylor &amp; Francis; Lang, (2019) “Nine Benefits and Uses of Lemon Peel,” [www.healthline.com/nutrition/lemon-peel]. 
     As a non-limiting method, to produce a single serving of the Herbal THC Detoxification Blend, about 2.0-6.0 g of dehydrated  Momordica charantia  is added to about 2.0-3.0 g of a mixed blend of elderflower, dandelion root, green tea leaves, lemon balm, crystalized ginger root, and lemon peel. Approximately 16 ounces or 500 ml of this blend is preferably steeped in boiling water for 7-10 minutes using tea sachet. The resulting Herbal THC Detoxification Blend can be immediately administered warm or as a cold drink or stored for later use. 
     The inventor has found that the most effective use of the plant to maintain its purgative properties is to directly freeze fresh plant material and only thaw before making the decoction, or using the fresh plant itself. Because the main ingredient has to be fresh or frozen, the decoction of blended herbs and  Mormodica charantia  has a shelf life of approximately 3-5 days under standard refrigeration temperatures and up to 7 days if the decoction solution is frozen. It is also contemplated that the Herbal THC Detoxification Blend can be made directly from Aqueous Decoction solution. 
     Alternatively, as yet another non-limiting example, 500 ml the Aqueous Decoction the  Mormodica charantia  described herein is used in which mixed blend of other ingredients is added. These additional ingredients can include, but are not limited to, elderflower, dandelion root, green tea leaves, lemon balm, crystalized ginger root, and lemon peel. The Aqueous Decoction plus the additional ingredients are then further steeped or boiled. As above, the resulting Herbal THC Detoxification Blend can be immediately administered warm or as a cold drink or stored for later use. The inventor has found that the Herbal THC Detoxification Blend has a shelf life of 12-36 months. 
     Method of Detoxification 
     The current invention is also drawn to methods of treating THC intoxication or clearing the bloodstream or urine of an individual of detectable THC or THC metabolites in anticipation of urine or blood test. Typically, several factors must be considered in determining the amount of the Herbal THC Detoxification Blend that must be consumed to clear the body of THC to undetectable limits. Body weight and the amount of THC are two of the most important factors to consider in determining how much consumed would have an impact on how much of the Herbal THC Detoxification Blend is needed to cleanse THC metabolites from the system. 
     As a non-limiting method to produce a single serving of the Herbal THC Detoxification Blend, 6.0 g of fresh  Momordica charantia  plant is added to about 6.0 g of a mixed blend of elderflower, dandelion root, green tea leaves, lemon balm, crystallized ginger root and lemon peel. Approximately 16 ounces or 500 ml of this blend is preferably steeped in boiling water for 7-10 minutes using a tea sachet. The resulting Herbal THC Detoxification Blend can be immediately administered warm or as a cold drink or stored for later use. 
     As a non-limiting example, the inventor has found that for moderate THC consumption, 16 ounces or 500 ml of the Herbal THC Detoxification Blend in addition to drinking half body weight of water in ounces throughout cleanse process typically works for the removal of THC or detectable metabolites in the bloodstream and urine. 
     For heavy consumption of THC, the inventor has found that 32 ounces of the Herbal THC Detoxification Blend is recommended. It was to be advantageous to drink the full 16 ounces of the Herbal THC Detoxification Blend within 1 hour and drinking half body weight in ounces within 4 hours of drinking cleanse. This will allow toxins and detectable THC metabolites to pass through urine. Once urine has a clear color (which typically happens within first 4 hours of drinking the Herbal THC Detoxification Blend), the cleanse is complete. 
     The inventor has determined that the success of the Herbal THC Detoxification Blend in clearing an individual&#39;s system of THC or detectable THC metabolites, also requires that the individual concurrently refrain from using THC or any THC product including so-called edibles. 
     Monitoring of the Efficacy of the Herbal THC Detoxification Blend 
     The efficacy can be easily monitored through the use of any commercially available home drug testing kit. It is contemplated that any commercially available test kit from online retailers or medical suppliers can be used. For example, the inventor contemplates that home test kits that test saliva, urine, or hair can be used. Test kits that test for THC or dateable metabolites in urine are preferred as they will typically mimic the tests to be used for employment or other official uses. 
     If home testing reveals that THC or its metabolites are still detectable, further consumption of the Herbal THC Detoxification Blend can commence. This process can be repeated as many times as necessary until THC or its detectable metabolites are no longer detectable in an individual&#39;s urine. 
     General guidelines suggest that THC metabolites can be detected for up to 90 days the in heavy, daily users without the use of the Herbal THC Detoxification Blend. The rate at which THC metabolites clear from an individual&#39;s system depends on their lifestyle, amount of exercise, diet and percentage of body fat. The inventor has found that with the use of the Herbal THC Detoxification Blend, detectable THC and its metabolites can be cleared from an individual&#39;s system within 24-48 hours. 
     Definitions 
     In the specification and in the claims, the terms “including” and “comprising” are open-ended terms and should be interpreted to mean “including, but not limited to . . . ” These terms encompass the more restrictive terms “consisting essentially of” and “consisting of”. 
     As used herein and in the appended claims, the singular forms “a”, “an”, and “the” include plural reference unless the context clearly dictates otherwise. As well, the terms “a” (or “an”), “one or more” and “at least one” can be used interchangeably herein. It is also to be noted that the terms “comprising”, “including”, and “having” can be used interchangeably. 
     Unless defined otherwise, all technical and scientific terms used herein have the same meanings as commonly understood by one of ordinary skill in the art to which this invention belongs. All publications and patents specifically mentioned herein are incorporated by reference in their entirety for all purposes including describing and disclosing the chemicals, instruments, statistical analyses and methodologies which are reported in the publications which might be used in connection with the invention. All references cited in this specification are to be taken as indicative of the level of skill in the art. Nothing herein is to be construed as an admission that the invention is not entitled to antedate such disclosure by virtue of prior invention. 
     The terms “about” or “approximately” as used herein mean within an acceptable error range for the particular value as determined by one of ordinary skill in the art, which will depend in part on how the value is measured or determined, i.e. the limitations of the measurement system. For example, “about” can mean within 3 or more than 3 standard deviations, per the practice in the art. Alternatively, particularly with respect to biological systems or processes, the term can mean within an order of magnitude, preferably within 5-fold and more preferably within 2-fold, of a value. 
     The following examples are offered by way of illustration and not limitation. 
     EXAMPLES 
     Example 1 
       Momordica charantia  Herbal THC Detoxification Blend 
     Table 1 shows an example of the amount of each ingredient for making the herbal tea blend. 
     
       
         
           
               
               
               
             
               
                   
                 TABLE 1 
               
               
                   
                   
               
               
                   
                   
                 To Make a Single 
               
               
                   
                 Ingredient 
                 Serving 
               
               
                   
                   
               
             
            
               
                   
               
            
           
           
               
               
               
               
            
               
                   
                 Momordica 
                 6.0  
                 g 
               
               
                   
                 Charantia 
                   
                   
               
               
                   
                 Green tea or 
                 3.0 
                 g 
               
               
                   
                 similar 
                   
                   
               
               
                   
                 Elderflower 
                 1.0 
                 g 
               
               
                   
                 Dandelion Root 
                 1.0  
                 g 
               
               
                   
                 Lemon Balm 
                 500 
                 mg 
               
               
                   
                 Ginger Root 
                 500 
                 mg 
               
               
                   
                 Water to 
                   
                   
               
               
                   
                 volume 
                   
                   
               
               
                   
                 TOTAL 
                 8.5 
                 g 
               
               
                   
                   
               
            
           
         
       
     
     The inventor contemplates that the amount of each ingredient may vary based on amount of detoxification required for example following a light consumption of THC, versus moderate consumption of THC versus heavy consumption of THC. 
     Example 2 
     Aqueous Decoction 
     A non-limiting example of an aqueous decoction is described below. The entire  Momordica charantia  plant is first mashed the plant, without the bitter melon, for maximum dissolution, and then boiling in about 600 ml distilled or spring water. The boiling allows for the extraction of oils, volatile organic compounds and various chemical substances from the plant. The mashed plant was boiled for about 15 minutes. 
     The bitter melon fruit is then added to the boiled decoction solution in addition to a sliced whole lemon. After decoction is brewed for an additional for about 12-15 minutes, the resulting solution is strained to remove the plant and lemon slices and any other remaining particles. 
     Once the Aqueous Decoction solution is strained, other ingredients can be added. As a non-limiting example, a sweetener such as  stevia  is added to improve the taste of the decoction. It is contemplated that the amount and type of sweetener can be varied according to individual preferences. 
     The resulting Aqueous Decoction solution is typically about 1500 ml. This typically yields about three 500 ml detoxification doses. 
     
       
         
           
               
               
               
             
               
                   
                 TABLE 2 
               
               
                   
                   
               
               
                   
                 Ingredient 
                 Amount 
               
               
                   
                   
               
             
            
               
                   
                 Momordica 
                 10.5 g 
               
               
                   
                 Charantia 
                   
               
               
                   
                 Lemon 
                 2 slices or 
               
               
                   
                   
                 to taste 
               
               
                   
                 Sweetener 
                 to taste 
               
               
                   
                 Water 
                 to volume 
               
               
                   
                 TOTAL 
                 2.0 L 
               
               
                   
                   
               
            
           
         
       
     
     The resulting solution has a shelf life of one week and can be frozen for up to one week to preserve. 
     Example 3 
     Testing Examples 
     Examples of 2 individuals who were voluntarily administered the Herbal THC Detoxification Blend and their subsequent THC testing results are shown below in Table 3. 
     
       
         
           
               
               
               
               
             
               
                 TABLE 3 
               
               
                   
               
               
                   
                   
                 Detoxification 
                   
               
               
                 Individual 
                 Issue 
                 Procedure 
                 Results 
               
               
                   
               
             
            
               
                 Female  
                 Required monthly 
                 drink 16 oz of 
                 All tests showed 
               
               
                 (28) 
                 drug tests during 
                 Herbal THC 
                 urine free of THC 
               
               
                 Pregnant 
                 course of pregnancy 
                 Detoxification  
                 metabolites despite 
               
               
                   
                 to detect possible 
                 Blend 2-6 hrs  
                 admitted inhalation 
               
               
                   
                 drug use; required 
                 prior to drug 
                 and smoking of 
               
               
                   
                 postpartum urine 
                 test being 
                 marijuana. 
               
               
                   
                 drug testing weekly 
                 administered 
                 other drugs that 
               
               
                   
                 for 12 consecutive 
                   
                 were in her system 
               
               
                   
                 months. 
                   
                 were also traced  
               
               
                   
                   
                   
                 (e.g. α-pyrrol- 
               
               
                   
                   
                   
                 idinopentio- 
               
               
                   
                   
                   
                 phenone, 
               
               
                   
                   
                   
                 “flakka,” “bath 
               
               
                   
                   
                   
                 salts) 
               
               
                 Female  
                 Prescribed various 
                 drink 16 ounces  
                 All tests showed 
               
               
                 (35-50) 
                 medications  
                 of Herbal THC 
                 urine free of THC 
               
               
                 Diagnosed  
                 for pain 
                 Detoxification  
                 metabolites despite 
               
               
                 with 
                 (e.g. hydrocodone 
                 Blend 12  
                 admitted inhalation 
               
               
                 Anxiety  
                 smokes marijuana 
                 hours prior to  
                 and smoking of 
               
               
                 Disorder 
                 to aide with side 
                 drug test being 
                 marijuana. 
               
               
                   
                 effects; 
                 administered 
                 prescription 
               
               
                   
                 required monthly 
                   
                 medications not 
               
               
                   
                 urine drug testing to 
                   
                 detected due to due 
               
               
                   
                 verify compliance 
                   
                 to Herbal THC 
               
               
                   
                 with prescription 
                   
                 Detoxification  
               
               
                   
                 medication and no 
                   
                 Blend 
               
               
                   
                 other drug use 
               
               
                   
               
            
           
         
       
     
     Although the foregoing invention has been described in some detail by way of illustration and example for purposes of clarity of understanding, it will be obvious that certain changes and modifications may be practiced within the scope of the claims.