Patent Publication Number: US-2003235820-A1

Title: Novel methods of diagnosis of metastatic colorectal cancer, compositions and methods of screening for modulators of metastatic colorectal cancer

Description:
CROSS-REFERENCES TO RELATED APPLICATIONS  
     [0001] The present application is related to U.S. S No. 60/272,206, filed Feb. 27, 2001, U.S. S No. 60/281,149, filed Apr. 2, 2001, and U.S. S No. 60/284,555, filed Apr. 17, 2001, all of which are herein incorporated by referenced in their entirety. 
    
    
     
       FIELD OF THE INVENTION  
       [0002] The invention relates to the identification of nucleic acid and protein expression profiles and nucleic acids, products, and antibodies thereto that are involved in metastatic colorectal cancer; and to the use of such expression profiles and compositions in diagnosis and therapy of metastatic colorectal cancer. The invention further relates to methods for identifying and using agents and/or targets that inhibit metastatic colorectal cancer.  
       BACKGROUND OF THE INVENTION  
       [0003] Cancer of the colon and/or rectum (referred to as “colorectal cancer”) are significant in Western populations and particularly in the United States. Cancers of the colon and rectum occur in both men and women most commonly after the age of 50. These develop as the result of a pathologic transformation of normal colon epithelium to an invasive cancer. There have been a number of recently characterized genetic alterations that have been implicated in colorectal cancer, including mutations in two classes of genes, tumor-suppressor genes and proto-oncogenes, with recent work suggesting that mutations in DNA repair genes may also be involved in tumorigenesis. For example, inactivating mutations of both alleles of the adenomatous polyposis coli (APC) gene, a tumor suppressor gene, appears to be one of the earliest events in colorectal cancer, and may even be the initiating event. Other genes implicated in colorectal cancer include the MCC gene, the p53 gene, the DCC (deleted in colorectal carcinoma) gene and other chromosome 18q genes, and genes in the TGF-β signaling pathway. For a review, see  Molecular Biology of Colorectal Cancer,  pp. 238-299, in  Curr. Probl. Cancer,  September/October 1997; see also Willams,  Colorectal Cancer  (1996); Kinsella &amp; Schofield,  Colorectal Cancer: A Scientific Perspective  (1993);  Colorectal Cancer: Molecular Mechanisms, Premalignant State and its Prevention  (Schiniegel &amp; Scholmerich eds., 2000);  Colorectal Cancer: New Aspects of molecular Biology and Their Clinical Applications  (Hanski et al., eds 2000); McArdle et al.,  Colorectal Cancer  (2000); Wanebo,  Colorectal Cancer  (1993); Levin,  The American Cancer Society: Colorectal Cancer  (1999);  Treatment of Hepatic Metastases of Colorectal Cancer  (Nordlinger &amp; Jaeck eds., 1993);  Management of Colorectal Cancer  (Dunitz et al., eds. 1998);  Cancer: Principles and Practice of Oncology  (Devita et al., eds. 2001);  Surgical Oncology: Contemporary Principles and Practice  (Kirby et al., eds. 2001); Offit,  Clinical Cancer Genetics: Risk Counseling and Management  (1997);  Radioimmunotherapy of Cancer  (Abrams &amp; Fritzberg eds. 2000); Fleming,  AJCC Cancer Staging Handbook  (1998);  Textbook of Radiation Oncology  (Leibel &amp; Phillips eds. 2000); and  Clinical Oncology  (Abeloff et al., eds. 2000).  
       [0004] Imaging of colorectal cancer for diagnosis has been problematic and limited.  
       [0005] In addition, metastasis of the tumor to the lumen, and metastasis of tumor cells to regional lymph nodes are important prognostic factors (see, e.g.,  PET in Oncology: Basics and Clinical Application  (Ruhlmann et al. eds. 1999). For example, five year survival rates drop from 80 percent in patients with no lymph node metastases to 45 to 50 percent in those patients who do have lymph node metastases. A recent report showed that micrometastases can be detected from lymph nodes using reverse transcriptase-PCR methods based on the presence of mRNA for carcinoembryonic antigen, which has previously been shown to be present in the vast majority of colorectal cancers but not in normal tissues. Liefers et al.,  New England J. of Med.  339(4):223 (1998). In addition, colorectal cancers often metastasize to the liver. However, the lack of information about the gene expression exhibited by these cancers limits the ability to effectively diagnose and treat the disease. Thus, methods for diagnosis and prognosis of metastatic colorectal cancer and effective treatment of colorectal cancer would be desirable. Accordingly, provided herein are methods that can be used in diagnosis and prognosis of metastatic colorectal cancer. Further provided are methods that can be used to screen candidate therapeutic agents for the ability to modulate, e.g., treat, colorectal cancer. Additionally, provided herein are molecular targets and compositions for therapeutic intervention in metastatic colorectal disease and other metastatic cancers.  
       SUMMARY OF THE INVENTION  
       [0006] The present invention therefore provides nueleotide sequences of genes that are up- and down-regulated in metastatic colorectal cancer cells. Such genes and the proteins they encode are useful for diagnostic and prognostic purposes, and also as targets for screening for therapeutic compounds that modulate metastatic colorectal cancer, such as antibodies. The methods of detecting nucleic acids of the invention or their encoded proteins can be used for a number of purposes. Examples include, early detection of colon cancers, monitoring and early detection of relapse following treatment of colon cancers, monitoring response to therapy of colon cancers, determining prognosis of colon cancers, directing therapy of colon cancers, selecting patients for postoperative chemotherapy or radiation therapy, selecting therapy, determining tumor prognosis, treatment, or response to treatment, and early detection of precancerous colon adenomas. Other aspects of the invention will become apparent to the skilled artisan by the following description of the invention.  
       [0007] In one aspect, the present invention provides a method of detecting a metastatic colorectal cancer-associated transcript in a cell from a patient, the method comprising contacting a biological sample from the patient with a polynucleotide that selectively hybridizes to a sequence at least 80% identical to a sequence as shown in Tables 1-26.  
       [0008] In one embodiment, the polynucleotide selectively hybridizes to a sequence at least 95% identical to a sequence as shown in Tables 1-26. In another embodiment, the polynucleotide comprises a sequence as shown in Tables 1-26.  
       [0009] In one embodiment, the biological sample is a tissue sample. In another embodiment, the biological sample comprises isolated nucleic acids, e.g., mRNA.  
       [0010] In one embodiment, the polynucleotide is labeled, e.g., with a fluorescent label.  
       [0011] In one embodiment, the polynucleotide is immobilized on a solid surface.  
       [0012] In one embodiment, the patient is undergoing a therapeutic regimen to treat metastatic colorectal cancer. In another embodiment, the patient is suspected of having metastatic colorectal cancer.  
       [0013] In one embodiment, the patient is a human.  
       [0014] In one embodiment, the method further comprises the step of amplifying nucleic acids before the step of contacting the biological sample with the polynucleotide.  
       [0015] In another aspect, the present invention provides methods of detecting polypeptide encoded by a metastatic colorectal cancer-associated transcript in a cell from a patient, the method comprising contacting a biological sample from the patient with an antibody that specifically binds a polypeptide encoded by a sequence at least 80% identical to a sequence as shown in Tables 1-26.  
       [0016] In another aspect, the present invention provides a method of monitoring the efficacy of a therapeutic treatment of metastatic colorectal cancer, the method comprising the steps of: (i) providing a biological sample from a patient undergoing the therapeutic treatment; and (ii) determining the level of a metastatic colorectal cancer-associated transcript in the biological sample by contacting the biological sample with a polynucleotide that selectively hybridizes to a sequence at least 80% identical to a sequence as shown in Tables 1-26., thereby monitoring the efficacy of the therapy.  
       [0017] In one embodiment, the method further comprises the step of: (iii) comparing the level of the metastatic colorectal cancer-associated transcript to a level of the metastatic colorectal cancer-associated transcript in a biological sample from the patient prior to, or earlier in, the therapeutic treatment.  
       [0018] In another aspect, the present invention provides a method of monitoring the efficacy of a therapeutic treatment of metastatic colorectal cancer, the method comprising the steps of: (i) providing a biological sample from a patient undergoing the therapeutic treatment; and (ii) determining the level of a metastatic colorectal cancer-associated antibody in the biological sample by contacting the biological sample with a polypeptide encoded by a polynucleotide that selectively hybridizes to a sequence at least 80% identical to a sequence as shown in Tables 1-26, wherein the polypeptide specifically binds to the metastatic colorectal cancer-associated antibody, thereby monitoring the efficacy of the therapy.  
       [0019] In one embodiment, the method further comprises the step of: (iii) comparing the level of the metastatic colorectal cancer-associated antibody to a level of the metastatic colorectal cancer-associated antibody in a biological sample from the patient prior to, or earlier in, the therapeutic treatment.  
       [0020] In another aspect, the present invention provides a method of monitoring the efficacy of a therapeutic treatment of metastatic colorectal cancer, the method comprising the steps of: (i) providing a biological sample from a patient undergoing the therapeutic treatment; and (ii) determining the level of a metastatic colorectal cancer-associated polypeptide in the biological sample by contacting the biological sample with an antibody, wherein the antibody specifically binds to a polypeptide encoded by a polynucleotide that selectively hybridizes to a sequence at least 80% identical to a sequence as shown in Tables 1-26, thereby monitoring the efficacy of the therapy.  
       [0021] In one embodiment, the method further comprises the step of: (iii) comparing the level of the metastatic colorectal cancer-associated polypeptide to a level of the metastatic colorectal cancer-associated polypeptide in a biological sample from the patient prior to, or earlier in, the therapeutic treatment.  
       [0022] In one aspect, the present invention provides an isolated nucleic acid molecule consisting of a polynucleotide sequence as shown in Tables 1-26.  
       [0023] In one embodiment, an expression vector or cell comprises the isolated nucleic acid.  
       [0024] In one aspect, the present invention provides an isolated polypeptide which is encoded by a nucleic acid molecule having polynucleotide sequence as shown in Tables 1-26.  
       [0025] In another aspect, the present invention provides an antibody that specifically binds to an isolated polypeptide which is encoded by a nucleic acid molecule having polynucleotide sequence as shown in Tables 1-26.  
       [0026] In one embodiment, the antibody is conjugated to an effector component, e.g., a fluorescent label, a radioisotope or a cytotoxic chemical.  
       [0027] In one embodiment, the antibody is an antibody fragment. In another embodiment, the antibody is humanized.  
       [0028] In one aspect, the present invention provides a method of detecting a metastatic colorectal cancer cell in a biological sample from a patient, the method comprising contacting the biological sample with an antibody as described herein.  
       [0029] In another aspect, the present invention provides a method of detecting antibodies specific to metastatic colorectal cancer in a patient, the method comprising contacting a biological sample from the patient with a polypeptide encoded by a nucleic acid comprises a sequence from Tables 1-26.  
       [0030] In another aspect, the present invention provides a method for identifying a compound that modulates a metastatic colorectal cancer-associated polypeptide, the method comprising the steps of: (i) contacting the compound with a metastatic colorectal cancer-associated polypeptide, the polypeptide encoded by a polynucleotide that selectively hybridizes to a sequence at least 80% identical to a sequence as shown in Tables 1-26; and (ii) determining the functional effect of the compound upon the polypeptide.  
       [0031] In one embodiment, the functional effect is a physical effect, an enzymatic effect, or a chemical effect.  
       [0032] In one embodiment, the polypeptide is expressed in a eukaryotic host cell or cell membrane. In another embodiment, the polypeptide is recombinant.  
       [0033] In one embodiment, the functional effect is determined by measuring ligand binding to the polypeptide.  
       [0034] In another aspect, the present invention provides a method of inhibiting proliferation of a metastatic colorectal cancer-associated cell to treat colorectal cancer in a patient, the method comprising the step of administering to the subject a therapeutically effective amount of a compound identified as described herein.  
       [0035] In one embodiment, the compound is an antibody.  
       [0036] In another aspect, the present invention provides a drug screening assay comprising the steps of: (i) administering a test compound to a mammal having colorectal cancer or a cell isolated therefrom; (ii) comparing the level of gene expression of a polynucleotide that selectively hybridizes to a sequence at least 80% identical to a sequence as shown in Tables 1-26. in a treated cell or mammal with the level of gene expression of the polynucleotide in a control cell or mammal, wherein a test compound that modulates the level of expression of the polynucleotide is a candidate for the treatment of colorectal cancer.  
       [0037] In one embodiment, the control is a mammal with colorectal cancer or a cell therefrom that has not been treated with the test compound. In another embodiment, the control is a normal cell or mammal.  
       [0038] In another aspect, the present invention provides a method for treating a mammal having colorectal cancer comprising administering a compound identified by the assay described herein.  
       [0039] In another aspect, the present invention provides a pharmaceutical composition for treating a mammal having colorectal cancer, the composition comprising a compound identified by the assay described herein and a physiologically acceptable excipient. 
     
    
    
     DETAILED DESCRIPTION OF THE INVENTION  
     [0040] In accordance with the objects outlined above, the present invention provides novel methods for diagnosis and treatment of colon and/or rectal cancer (e.g. colorectal cancer), including metastatic colorectal cancers, as well as methods for screening for compositions which modulate colorectal cancer. By “metastatic colorectal cancer” herein is meant a colon and/or rectal tumor or cancer that is classified as Dukes stage C or D (see, e.g., Cohen et al.,  Cancer of the Colon, in Cancer: Principles and Practice of Oncology,  pp. 1144-1197 (Devita et al., eds., 5 th  ed. 1997); see also  Harrison &#39;s Principles of Internal Medicine,  pp. 1289-129 (Wilson et al., eds., 12 th  ed., 1991). “Treatment, monitoring, detection or modulation of metastatic colorectal cancer” includes treatment, monitoring, detection, or modulation of metastatic colorectal disease in those patients who have metastatic colorectal disease (Dukes stage C or D). In Dukes stage A, the tumor has penetrated into, but not through, the bowel wall. In Dukes stage B, the tumor has penetrated through the bowel wall but there is not yet any lymph involvement. In Dukes stage C, the cancer involves regional lymph nodes. In Dukes stage D, there is distant metastasis, e.g., liver, lung, etc.  
     [0041] Tables 1-26 provide UniGene cluster identification numbers for the nucleotide sequence of genes that exhibit increased or decreased expression in metastasizing colorectal cancer samples. Tables 1-26 also provide an exemplar accession number that provides a nucleotide sequence that is part of the UniGene cluster. In Tables 1-26, the ratio provided represents primary tumor samples from known Dukes B stage survivors vs. liver metastasis samples from patients with metastatic colorectal cancer. In these samples, the identified genes are underexpressed in the metastatic samples, as the ratio is greater than one, preferably 1.5 or greater, more preferably 2.0 or greater. In Tables 1-26, the ratio provided represents liver metastasis samples from patients with known metastatic colorectal cancer vs. known primary tumor samples from Dukes B stage survivors. In these samples, the identified genes are overexpressed in the metastatic samples, as the ratio is greater than one, preferably 1.5 or greater, more preferably 2.0 or greater. In Tables 1-26, the ratio provided represents primary tumor samples from known Dukes B stage survivors vs. liver metastasis samples from patients with metastatic colorectal cancer. In these samples, the identified genes are overexpressed in the metastatic samples, as the ratio is less than one, preferably 0.5 or less, more preferably 0.25 or less. Survivors are subjects who have been disease free for five years or longer.  
     [0042] In Tables 1-26, the ratio provided represents liver metastasis samples from patients with known metastatic disease vs. tissue samples from normal colon tissue. In these samples, the identified genes are overexpressed in the metastatic samples, as the ratio is greater than one, preferably 1.5 or greater, more preferably 2.0 or greater. In Tables 1-26, the ratio represents liver metastasis samples from patients with known metastatic disease vs. tissue samples from normal colon tissue. In these samples, the identified genes are underexpressed in the metastatic samples, as the ratio is less than one, preferably 0.5 or less, more preferably 0.25 or less.  
     [0043] One of skill will recognize that although the sequences identified in Tables 1-26 exhibited increased or decreased expression in metastasizing colorectal cancer samples, the sequences of the invention, and their encoded proteins, can be used to diagnose, treat or prevent cancers in patients with Dukes stage A or B colorectal cancers. Alteration of gene expression for a gene in Tables 1-26 may be more likely or less likely to indicate that the subject will progress to metastatic disease. The sequences can also be used to diagnose, treat or prevent precancerous or benign conditions such as precancerous colon adenomas. Alteration of gene expression for a gene in Tables 1-26 may or may not indicate that the subject is more likely to progress to cancer or to metastatic disease. Thus, although the specification focuses primarily on metastasizing colorectal cancer, the methods described below can also be applied to non-metastasizing colorectal cancers (e.g., Dukes stages A and B) and precancerous or benign conditions (e.g., precancerous adenomas) as well.  
     [0044] Definitions  
     [0045] The term “metastatic colorectal cancer protein” or “metastatic colorectal cancer polynucleotide” or “metastatic colorectal cancer-associated transcript” refers to nucleic acid and polypeptide polymorphic variants, alleles, mutants, and interspecies homologs that: (1) have a nucleotide sequence that has greater than about 60% nucleotide sequence identity, 65%, 70%, 75%, 80%, 85%, 90%, preferably 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98% or 99% or greater nucleotide sequence identity, preferably over a region of over a region of at least about 25, 50, 100, 200, 500, 1000, or more nucleotides, to a nucleotide sequence of or associated with a UniGene cluster of Tables 1-26; (2) bind to antibodies, e.g., polyclonal antibodies, raised against an immunogen comprising an amino acid sequence encoded by a nucleotide sequence of or associated with a UniGene cluster of Tables 1-26, and conservatively modified variants thereof; (3) specifically hybridize under stringent hybridization conditions to a nucleic acid sequence, or the complement thereof of Tables 1-26 and conservatively modified variants thereof or (4) have an amino acid sequence that has greater than about 60% amino acid sequence identity, 65%, 70%, 75%, 80%, 85%, 90%, preferably 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98% or 99% or greater amino sequence identity, preferably over a region of over a region of at least about 25, 50, 100, 200, 500, 1000, or more amino acid, to an amino acid sequence encoded by a nucleotide sequence of or associated with a UniGene cluster of Tables 1-26. A polynucleotide or polypeptide sequence is typically from a mammal including, but not limited to, primate, e.g., human; rodent, e.g., rat, mouse, hamster; cow, pig, horse, sheep, or other mammal. A “metastatic colorectal cancer polypeptide” and a “metastatic colorectal cancer polynucleotide,” include both naturally occurring or recombinant.  
     [0046] A “fill length” metastatic colorectal cancer protein or nucleic acid refers to a metastatic colorectal cancer polypeptide or polynucleotide sequence, or a variant thereof, that contains all of the elements normally contained in one or more naturally occurring, wild type metastatic colorectal cancer polynucleotide or polypeptide sequences. The “full length” may be prior to, or after, various stages of post-translation processing or splicing, including alternative splicing.  
     [0047] “Biological sample” as used herein is a sample of biological tissue or fluid that contains nucleic acids or polypeptides, e.g., of a metastatic colorectal cancer protein, polynucleotide or transcript. Such samples include, but are not limited to, tissue isolated from primates, e.g., humans, or rodents, e.g., mice, and rats. Biological samples may also include sections of tissues such as biopsy and autopsy samples, frozen sections taken for histologic purposes, blood, plasma, serum, sputum, stool, tears, mucus, hair, skin, etc. Biological samples also include explants and primary and/or transformed cell cultures derived from patient tissues. A biological sample is typically obtained from a eukaryotic organism, most preferably a mammal such as a primate, e.g., chimpanzee or human; cow; dog; cat; a rodent, e.g., guinea pig, rat, mouse; rabbit; or other mammal; or a bird; reptile; fish.  
     [0048] “Providing a biological sample” means to obtain a biological sample for use in methods described in this invention. Most often, this will be done by removing a sample of cells from an animal, but can also be accomplished by using previously isolated cells (e.g., isolated by another person, at another time, and/or for another purpose), or by performing the methods of the invention in vivo. Archival tissues, having treatment or outcome history, will be particularly useful.  
     [0049] The terms “identical” or percent “identity,” in the context of two or more nucleic acids or polypeptide sequences, refer to two or more sequences or subsequences that are the same or have a specified percentage of amino acid residues or nucleotides that are the same (i.e., about 60% identity, preferably 70%, 75%, 80%, 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or higher identity over a specified region, when compared and aligned for maximum correspondence over a comparison window or designated region) as measured using a BLAST or BLAST 2.0 sequence comparison algorithms with default parameters described below, or by manual alignment and visual inspection (see, e.g. NCBI web site http://www.ncbi.nlm.nih.gov/BLAST/ or the like). Such sequences are then said to be “substantially identical.” This definition also refers to, or may be applied to, the compliment of a test sequence. The definition also includes sequences that have deletions and/or additions, as well as those that have substitutions, as well as naturally occurring, e.g., polymorphic or allelic variants, and man-made variants. As described below, the preferred algorithms can account for gaps and the like. Preferably, identity exists over a region that is at least about 25 amino acids or nucleotides in length, or more preferably over a region that is 50-100 amino acids or nucleotides in length.  
     [0050] For sequence comparison, typically one sequence acts as a reference sequence, to which test sequences are compared. When using a sequence comparison algorithm, test and reference sequences are entered into a computer, subsequence coordinates are designated, if necessary, and sequence algorithm program parameters are designated. Preferably, default program parameters can be used, or alternative parameters can be designated. The sequence comparison algorithm then calculates the percent sequence identities for the test sequences relative to the reference sequence, based on the program parameters.  
     [0051] A “comparison window”, as used herein, includes reference to a segment of one of the number of contiguous positions selected from the group consisting typically of from 20 to 600, usually about 50 to about 200, more usually about 100 to about 150 in which a sequence may be compared to a reference sequence of the same number of contiguous positions after the two sequences are optimally aligned. Methods of alignment of sequences for comparison are well-known in the art. Optimal alignment of sequences for comparison can be conducted, e.g., by the local homology algorithm of Smith &amp; Waterman,  Adv. Appl. Math.  2:482 (1981), by the homology alignment algorithm of Needleman &amp; Wunsch,  J. Mol. Biol.  48:443 (1970), by the search for similarity method of Pearson &amp; Lipman,  Proc. Nat&#39;l. Acad. Sci. USA  85:2444 (1988), by computerized implementations of these algorithms (GAP, BESTFIT, FASTA, and TFASTA in the Wisconsin Genetics Software Package, Genetics Computer Group, 575 Science Dr., Madison, Wis.), or by manual alignment and visual inspection (see, e.g.,  Current Protocols in Molecular Biology  (Ausubel et al., eds. 1995 supplement)).  
     [0052] Preferred examples of algorithms that are suitable for determining percent sequence identity and sequence similarity include the BLAST and BLAST 2.0 algorithms, which are described in Altschul et al.,  Nuc. Acids Res.  25:3389-3402 (1977) and Altschul et al.,  J. Mol. Biol.  215:403-410 (1990). BLAST and BLAST 2.0 are used, with the parameters described herein, to determine percent sequence identity for the nucleic acids and proteins of the invention. Software for performing BLAST analyses is publicly available through the National Center for Biotechnology Information (http://www.ncbi.nlm.nih.gov/). This algorithm involves first identifying high scoring sequence pairs (HSPs) by identifying short words of length W in the query sequence, which either match or satisfy some positive-valued threshold score T when aligned with a word of the same length in a database sequence. T is referred to as the neighborhood word score threshold (Altschul et al., supra). These initial neighborhood word hits act as seeds for initiating searches to find longer HSPs containing them. The word hits are extended in both directions along each sequence for as far as the cumulative alignment score can be increased. Cumulative scores are calculated using, e.g., for nucleotide sequences, the parameters M (reward score for a pair of matching residues; always &gt;0) and N (penalty score for mismatching residues; always &lt;0). For amino acid sequences, a scoring matrix is used to calculate the cumulative score. Extension of the word hits in each direction are halted when: the cumulative alignment score falls off by the quantity X from its maximum achieved value; the cumulative score goes to zero or below, due to the accumulation of one or more negative-scoring residue alignments; or the end of either sequence is reached. The BLAST algorithm parameters W, T, and X determine the sensitivity and speed of the alignment. The BLASTN program (for nucleotide sequences) uses as defaults a wordlength (W) of 11, an expectation (E) of 10, M=5, N=−4 and a comparison of both strands. For amino acid sequences, the BLASTP program uses as defaults a wordlength of 3, and expectation (E) of 10, and the BLOSUM62 scoring matrix (see Henikoff&amp; Henikoff,  Proc. Natl. Acad. Sci. USA  89:10915 (1989)) alignments (B) of 50, expectation (E) of 10, M=5, N=−4, and a comparison of both strands.  
     [0053] The BLAST algorithm also performs a statistical analysis of the similarity between two sequences (see, e.g., Karlin &amp; Altschul,  Proc. Nat&#39;l. Acad. Sci. USA  90:5873-5787 (1993)). One measure of similarity provided by the BLAST algorithm is the smallest sum probability (P(N)), which provides an indication of the probability by which a match between two nucleotide or amino acid sequences would occur by chance. For example, a nucleic acid is considered similar to a reference sequence if the smallest sum probability in a comparison of the test nucleic acid to the reference nucleic acid is less than about 0.2, more preferably less than about 0.01, and most preferably less than about 0.001. Log values may be large negative numbers, e.g., 5, 10, 20, 30, 40, 40, 70, 90, 110, 150, 170, etc.  
     [0054] An indication that two nucleic acid sequences or polypeptides are substantially identical is that the polypeptide encoded by the first nucleic acid is immunologically cross reactive with the antibodies raised against the polypeptide encoded by the second nucleic acid, as described below. Thus, a polypeptide is typically substantially identical to a second polypeptide, e.g., where the two peptides differ only by conservative substitutions. Another indication that two nucleic acid sequences are substantially identical is that the two molecules or their complements hybridize to each other under stringent conditions, as described below. Yet another indication that two nucleic acid sequences are substantially identical is that the same primers can be used to amplify the sequences.  
     [0055] A “host cell” is a naturally occurring cell or a transformed cell that contains an expression vector and supports the replication or expression of the expression vector. Host cells may be cultured cells, explants, cells in vivo, and the like. Host cells may be prokaryotic cells such as  E. coli , or eukaryotic cells such as yeast, insect, amphibian, or mammalian cells such as CHO, HeLa, and the like (see, e.g., the American Type Culture Collection catalog or web site, www.atcc.org).  
     [0056] The terms “isolated,” “purified,” or “biologically pure” refer to material that is substantially or essentially free from components that normally accompany it as found in its native state. Purity and homogeneity are typically determined using analytical chemistry techniques such as polyacrylamide gel electrophoresis or high performance liquid chromatography. A protein or nucleic acid that is the predominant species present in a preparation is substantially purified. In particular, an isolated nucleic acid is separated from some open reading frames that naturally flank the gene and encode proteins other than protein encoded by the gene. The term “purified” in some embodiments denotes that a nucleic acid or protein gives rise to essentially one band in an electrophoretic gel. Preferably, it means that the nucleic acid or protein is at least 85% pure, more preferably at least 95% pure, and most preferably at least 99% pure. “Purify” or “purification” in other embodiments means removing at least one contaminant from the composition to be purified. In this sense, purification does not require that the purified compound be homogenous, e.g., 100% pure.  
     [0057] The terms “polypeptide,” “peptide” and “protein” are used interchangeably herein to refer to a polymer of amino acid residues. The terms apply to amino acid polymers in which one or more amino acid residue is an artificial chemical mimetic of a corresponding naturally occurring amino acid, as well as to naturally occurring amino acid polymers, those containing modified residues, and non-naturally occurring amino acid polymer.  
     [0058] The term “amino acid” refers to naturally occurring and synthetic amino acids, as well as amino acid analogs and amino acid mimetics that function similarly to the naturally occurring amino acids. Naturally occurring amino acids are those encoded by the genetic code, as well as those amino acids that are later modified, e.g., hydroxyproline, γ-carboxyglutamate, and O-phosphoserine. Amino acid analogs refers to compounds that have the same basic chemical structure as a naturally occurring amino acid, e.g., an a carbon that is bound to a hydrogen, a carboxyl group, an amino group, and an R group, e.g., homoserine, norleucine, methionine sulfoxide, methionine methyl sulfonium. Such analogs may have modified R groups (e.g., norleucine) or modified peptide backbones, but retain the same basic chemical structure as a naturally occurring amino acid. Amino acid mimetics refers to chemical compounds that have a structure that is different from the general chemical structure of an amino acid, but that functions similarly to a naturally occurring amino acid.  
     [0059] Amino acids may be referred to herein by either their commonly known three letter symbols or by the one-letter symbols recommended by the IUPAC-IUB Biochemical Nomenclature Commission. Nucleotides, likewise, may be referred to by their commonly accepted single-letter codes.  
     [0060] “Conservatively modified variants” applies to both amino acid and nucleic acid sequences. With respect to particular nucleic acid sequences, conservatively modified variants refers to those nucleic acids which encode identical or essentially identical amino acid sequences, or where the nucleic acid does not encode an amino acid sequence, to essentially identical or associated, e.g., naturally contiguous, sequences. Because of the degeneracy of the genetic code, a large number of functionally identical nucleic acids encode most proteins. For instance, the codons GCA, GCC, GCG and GCU all encode the amino acid alanine. Thus, at every position where an alanine is specified by a codon, the codon can be altered to another of the corresponding codons described without altering the encoded polypeptide. Such nucleic acid variations are “silent variations,” which are one species of conservatively modified variations. Every nucleic acid sequence herein which encodes a polypeptide also describes silent variations of the nucleic acid. One of skill will recognize that in certain contexts each codon in a nucleic acid (except AUG, which is ordinarily the only codon for methionine, and TGG, which is ordinarily the only codon for tryptophan) can be modified to yield a functionally identical molecule. Accordingly, often silent variations of a nucleic acid which encodes a polypeptide is implicit in a described sequence with respect to the expression product, but not with respect to actual probe sequences.  
     [0061] As to amino acid sequences, one of skill will recognize that individual substitutions, deletions or additions to a nucleic acid, peptide, polypeptide, or protein sequence which alters, adds or deletes a single amino acid or a small percentage of amino acids in the encoded sequence is a “conservatively modified variant” where the alteration results in the substitution of an amino acid with a chemically similar amino acid. Conservative substitution tables providing functionally similar amino acids are well known in the art. Such conservatively modified variants are in addition to and do not exclude polymorphic variants, interspecies homologs, and alleles of the invention.  
     [0062] The following eight groups each contain amino acids that are typically conservative substitutions for one another: 1) Alanine (A), Glycine (G); 2) Aspartic acid (D), Glutamic acid (E); 3) Asparagine (N), Glutamine (O); 4) Arginine (R), Lysine (K); 5) Isoleucine (I), Leucine (L), Methionine (M), Valine (V); 6) Phenylalanine (F), Tyrosine (Y), Tryptophan (W); 7) Serine (S), Threonine (T); and 8) Cysteine (C), Methionine (M) (see, e.g., Creighton,  Proteins  (1984)).  
     [0063] Macromolecular structures such as polypeptide structures can be described in terms of various levels of organization. For a general discussion of this organization, see, e.g., Alberts et al.,  Molecular Biology of the Cell  (3 rd  ed., 1994) and Cantor &amp; Schimmel,  Biophysical Chemistry Part I. The Conformation of Biological Macromolecules  (1980). “Primary structure” refers to the amino acid sequence of a particular peptide. “Secondary structure” refers to locally ordered, three dimensional structures within a polypeptide. These structures are commonly known as domains. Domains are portions of a polypeptide that often form a compact unit of the polypeptide and are typically 25 to approximately 500 amino acids long. Typical domains are made up of sections of lesser organization such as stretches of β-sheet and α-helices. “Tertiary structure” refers to the complete three dimensional structure of a polypeptide monomer. “Quaternary structure” refers to the three dimensional structure formed, usually by the noncovalent association of independent tertiary units. Anisotropic terms are also known as energy terms.  
     [0064] “Nucleic acid” or “oligonucleotide” or “polynucleotide” or grammatical equivalents used herein means at least two nucleotides covalently linked together. Oligonucleotides are typically from about 5, 6, 7, 8, 9, 10, 12, 15, 25, 30, 40, 50 or more nucleotides in length, up to about 100 nucleotides in length. Nucleic acids and polynucleotides are a polymers of any length, including longer lengths, e.g., 200, 300, 500, 1000, 2000, 3000, 5000, 7000, 10,000, etc. A nucleic acid of the present invention will generally contain phosphodiester bonds, although in some cases, nucleic acid analogs are included that may have alternate backbones, comprising, e.g., phosphoramidate, phosphorothioate, phosphorodithioate, or O-methylphophoroamidite linkages (see Eckstein, Oligonucleotides and Analogues: A Practical Approach, Oxford University Press); and peptide nucleic acid backbones and linkages. Other analog nucleic acids include those with positive backbones; non-ionic backbones, and non-ribose backbones, including those described in U.S. Pat. Nos. 5,235,033 and 5,034,506, and Chapters 6 and 7, ASC Symposium Series 580 , Carbohydrate Modifications in Antisense Research,  Sanghui &amp; Cook, eds. Nucleic acids containing one or more carbocyclic sugars are also included within one definition of nucleic acids. Modifications of the ribose-phosphate backbone may be done for a variety of reasons, e.g. to increase the stability and half-life of such molecules in physiological environments or as probes on a biochip. Mixtures of naturally occurring nucleic acids and analogs can be made; alternatively, mixtures of different nucleic acid analogs, and mixtures of naturally occurring nucleic acids and analogs may be made.  
     [0065] Particularly preferred are peptide nucleic acids (PNA) which includes peptide nucleic acid analogs. These backbones are substantially non-ionic under neutral conditions, in contrast to the highly charged phosphodiester backbone of naturally occurring nucleic acids. This results in two advantages. First, the PNA backbone exhibits improved hybridization kinetics. PNAs have larger changes in the melting temperature (T m ) for mismatched versus perfectly matched basepairs. DNA and RNA typically exhibit a 2-4° C. drop in T m  for an internal mismatch. With the non-ionic PNA backbone, the drop is closer to 7-9° C. Similarly, due to their non-ionic nature, hybridization of the bases attached to these backbones is relatively insensitive to salt concentration. In addition, PNAs are not degraded by cellular enzymes, and thus can be more stable.  
     [0066] The nucleic acids may be single stranded or double stranded, as specified, or contain portions of both double stranded or single stranded sequence. As will be appreciated by those in the art, the depiction of a single strand also defines the sequence of the complementary strand; thus the sequences described herein also provide the complement of the sequence. The nucleic acid may be DNA, both genomic and cDNA, RNA or a hybrid, where the nucleic acid may contain combinations of deoxyribo- and ribo-nucleotides, and combinations of bases, including uracil, adenine, thymine, cytosine, guanine, inosine, xanthine hypoxanthine, isocytosine, isoguanine, etc. “Transcript” typically refers to a naturally occurring RNA, e.g., a pre-mRNA, hnRNA, or mRNA. As used herein, the term “nucleoside” includes nucleotides and nucleoside and nucleotide analogs, and modified nucleosides such as amino modified nucleosides. In addition, “nucleoside” includes non-naturally occurring analog structures. Thus, e.g. the individual units of a peptide nucleic acid, each containing a base, are referred to herein as a nucleoside.  
     [0067] A “label” or a “detectable moiety” is a composition detectable by spectroscopic, photochemical, biochemical, immunochemical, chemical, or other physical means. For example, useful labels include  32 P, fluorescent dyes, electron-dense reagents, enzymes (e.g., as commonly used in an ELISA), biotin, digoxigenin, or haptens and proteins or other entities which can be made detectable, e.g., by incorporating a radiolabel into the peptide or used to detect antibodies specifically reactive with the peptide.  
     [0068] An “effector” or “effector moiety” or “effector component” is a molecule that is bound (or linked, or conjugated), either covalently, through a linker or a chemical bond, or noncovalently, through ionic, van der Waals, electrostatic, or hydrogen bonds, to an antibody. The “effector” can be a variety of molecules including, e.g., detection moieties including radioactive compounds, fluorescent compounds, an enzyme or substrate, tags such as epitope tags, a toxin; activatable moieties, a chemotherapeutic agent; a lipase; an antibiotic; or a radioisotope emitting “hard” e.g., beta radiation.  
     [0069] A “labeled nucleic acid probe or oligonucleotide” is one that is bound, either covalently, through a linker or a chemical bond, or noncovalently, through ionic, van der Waals, electrostatic, or hydrogen bonds to a label such that the presence of the probe may be detected by detecting the presence of the label bound to the probe. Alternatively, method using high affinity interactions may achieve the same results where one of a pair of binding partners binds to the other, e.g., biotin, streptavidin.  
     [0070] As used herein a “nucleic acid probe or oligonucleotide” is defined as a nucleic acid capable of binding to a target nucleic acid of complementary sequence through one or more types of chemical bonds, usually through complementary base pairing, usually through hydrogen bond formation. As used herein, a probe may include natural (i.e., A, G, C, or T) or modified bases (7-deazaguanosine, inosine, etc.). In addition, the bases in a probe may be joined by a linkage other than a phosphodiester bond, so long as it does not functionally interfere with hybridization. Thus, e.g., probes may be peptide nucleic acids in which the constituent bases are joined by peptide bonds rather than phosphodiester linkages. It will be understood by one of skill in the art that probes may bind target sequences lacking complete complementarity with the probe sequence depending upon the stringency of the hybridization conditions. The probes are preferably directly labeled as with isotopes, chromophores, lumiphores, chromogens, or indirectly labeled such as with biotin to which a streptavidin complex may later bind. By assaying for the presence or absence of the probe, one can detect the presence or absence of the select sequence or subsequence. Diagnosis or prognosis may be based at the genomic level, or at the level of RNA or protein expression.  
     [0071] The term “recombinant” when used with reference, e.g., to a cell, or nucleic acid, protein, or vector, indicates that the cell, nucleic acid, protein or vector, has been modified by the introduction of a heterologous nucleic acid or protein or the alteration of a native nucleic acid or protein, or that the cell is derived from a cell so modified. Thus, e.g., recombinant cells express genes that are not found within the native (non-recombinant) form of the cell or express native genes that are otherwise abnormally expressed, under expressed or not expressed at all. By the term “recombinant nucleic acid” herein is meant nucleic acid, originally formed in vitro, in general, by the manipulation of nucleic acid, e.g., using polymerases and endonucleases, in a form not normally found in nature. In this manner, operably linkage of different sequences is achieved. Thus an isolated nucleic acid, in a linear form, or an expression vector formed in vitro by ligating DNA molecules that are not normally joined, are both considered recombinant for the purposes of this invention. It is understood that once a recombinant nucleic acid is made and reintroduced into a host cell or organism, it will replicate non-recombinantly, i.e., using the in vivo cellular machinery of the host cell rather than in vitro manipulations; however, such nucleic acids, once produced recombinantly, although subsequently replicated non-recombinantly, are still considered recombinant for the purposes of the invention. Similarly, a “recombinant protein” is a protein made using recombinant techniques, i.e., through the expression of a recombinant nucleic acid as depicted above.  
     [0072] The term “heterologous” when used with reference to portions of a nucleic acid indicates that the nucleic acid comprises two or more subsequences that are not normally found in the same relationship to each other in nature. For instance, the nucleic acid is typically recombinantly produced, having two or more sequences, e.g., from unrelated genes arranged to make a new functional nucleic acid, e.g., a promoter from one source and a coding region from another source. Similarly, a heterologous protein will often refer to two or more subsequences that are not found in the same relationship to each other in nature (e.g., a fusion protein).  
     [0073] A “promoter” is defined as an array of nucleic acid control sequences that direct transcription of a nucleic acid. As used herein, a promoter includes necessary nucleic acid sequences near the start site of transcription, such as, in the case of a polymerase II type promoter, a TATA element. A promoter also optionally includes distal enhancer or repressor elements, which can be located as much as several thousand base pairs from the start site of transcription. A “constitutive” promoter is a promoter that is active under most environmental and developmental conditions. An “inducible” promoter is a promoter that is active under environmental or developmental regulation. The term “operably linked” refers to a functional linkage between a nucleic acid expression control sequence (such as a promoter, or array of transcription factor binding sites) and a second nucleic acid sequence, wherein the expression control sequence directs transcription of the nucleic acid corresponding to the second sequence.  
     [0074] An “expression vector” is a nucleic acid construct, generated recombinantly or synthetically, with a series of specified nucleic acid elements that permit transcription of a particular nucleic acid in a host cell. The expression vector can be part of a plasmid, virus, or nucleic acid fragment. Typically, the expression vector includes a nucleic acid to be transcribed operably linked to a promoter.  
     [0075] The phrase “selectively (or specifically) hybridizes to” refers to the binding, duplexing, or hybridizing of a molecule only to a particular nucleotide sequence under stringent hybridization conditions when that sequence is present in a complex mixture (e.g., total cellular or library DNA or RNA).  
     [0076] The phrase “stringent hybridization conditions” refers to conditions under which a probe will hybridize to its target subsequence, typically in a complex mixture of nucleic acids, but to essentially no other sequences. Stringent conditions are sequence-dependent and will be different in different circumstances. Longer sequences hybridize specifically at higher temperatures. An extensive guide to the hybridization of nucleic acids is found in Tijssen,  Techniques in Biochemistry and Molecular Biology—Hybridization with Nucleic Probes, “ Overview of principles of hybridization and the strategy of nucleic acid assays” (1993). Generally, stringent conditions are selected to be about 5-10° C. lower than the thermal melting point (T m ) for the specific sequence at a defined ionic strength pH. The T m  is the temperature (under defined ionic strength, pH, and nucleic concentration) at which 50% of the probes complementary to the target hybridize to the target sequence at equilibrium (as the target sequences are present in excess, at T m , 50% of the probes are occupied at equilibrium). Stringent conditions will be those in which the salt concentration is less than about 1.0 M sodium ion, typically about 0.01 to 1.0 M sodium ion concentration (or other salts) at pH 7.0 to 8.3 and the temperature is at least about 30° C. for short probes (e.g., 10 to 50 nucleotides) and at least about 60° C. for long probes (e.g., greater than 50 nucleotides). Stringent conditions may also be achieved with the addition of destabilizing agents such as formamide. For selective or specific hybridization, a positive signal is at least two times background, preferably 10 times background hybridization. Exemplary stringent hybridization conditions are often: 50% formamide, 5×SSC, and 1% SDS, incubating at 42° C., or, 5×SSC, 1% SDS, incubating at 65° C., with wash in 0.2×SSC, and 0.1% SDS at 65° C. For PCR, a temperature of about 36° C. is typical for low stringency amplification, although annealing temperatures may vary between about 32° C. and 48° C. depending on primer length. For high stringency PCR amplification, a temperature of about 62° C. is typical, although high stringency annealing temperatures can range from about 50° C. to about 65° C., depending on the primer length and specificity. Typical cycle conditions for both high and low stringency amplifications include a denaturation phase of 90° C.-95° C. for 30 sec—2 min., an annealing phase lasting 30 sec.—2 min., and an extension phase of about 72° C. for 1-2 min. Protocols and guidelines for low and high stringency amplification reactions are provided, e.g., in Innis et al.,  PCR Protocols, A Guide to Methods and Applications  (1990).  
     [0077] Nucleic acids that do not hybridize to each other under stringent conditions are still substantially identical if the polypeptides which they encode are substantially identical. This occurs, e.g., when a copy of a nucleic acid is created using the maximum codon degeneracy permitted by the genetic code. In such cases, the nucleic acids typically hybridize under moderately stringent hybridization conditions. Exemplary “moderately stringent hybridization conditions” include a hybridization in a buffer of 40% formamide, 1 M NaCl, 1% SDS at 37° C., and a wash in 1×SSC at 45° C. A positive hybridization is at least twice background. Those of ordinary skill will readily recognize that alternative hybridization and wash conditions can be utilized to provide conditions of similar stringency. Additional guidelines for determining hybridization parameters are provided in numerous reference, e.g., and Current Protocols in Molecular Biology, ed. Ausubel, et al.  
     [0078] The phrase “functional effects” in the context of assays for testing compounds that modulate activity of a metastatic colorectal cancer protein includes the determination of a parameter that is indirectly or directly under the influence of the metastatic colorectal cancer protein or nucleic acid, e.g., an enzymatic, functional, physical, or chemical effect, such as the ability to decrease metastatic colorectal cancer. It includes ligand binding activity; cell growth on soft agar; anchorage dependence; contact inhibition and density limitation of growth; cellular proliferation; cellular transformation; growth factor or serum dependence; tumor specific marker levels; invasiveness into Matrigel; tumor growth and metastasis in vivo; mRNA and protein expression in cells undergoing metastasis, and other characteristics of metastatic colorectal cancer cells. “Functional effects” include in vitro, in vivo, and ex vivo activities.  
     [0079] By “determining the functional effect” is meant assaying for a compound that increases or decreases a parameter that is indirectly or directly under the influence of a metastatic colorectal cancer protein sequence, e.g., functional, enzymatic, physical and chemical effects. Such functional effects can be measured by any means known to those skilled in the art, e.g., changes in spectroscopic characteristics (e.g., fluorescence, absorbance, refractive index), hydrodynamic (e.g., shape), chromatographic, or solubility properties for the protein, measuring inducible markers or transcriptional activation of the metastatic colorectal cancer protein; measuring binding activity or binding assays, e.g., binding to antibodies or other ligands, and measuring cellular proliferation. Determination of the functional effect of a compound on metastatic colorectal cancer can also be performed using metastatic colorectal cancer assays known to those of skill in the art such as an in vitro assays, e.g., cell growth on soft agar; anchorage dependence; contact inhibition and density limitation of growth; cellular proliferation; cellular transformation; growth factor or serum dependence; tumor specific marker levels; invasiveness into Matrigel; tumor growth and metastasis in vivo; mRNA and protein expression in cells undergoing metastasis, and other characteristics of metastatic colorectal cancer cells. The functional effects can be evaluated by many means known to those skilled in the art, e.g., microscopy for quantitative or qualitative measures of alterations in morphological features, measurement of changes in RNA or protein levels for metastatic colorectal cancer-associated sequences, measurement of RNA stability, identification of downstream or reporter gene expression (CAT, luciferase, β-gal, GFP and the like), e.g., via chemiluminescence, fluorescence, colorimetric reactions, antibody binding, inducible markers, and ligand binding assays.  
     [0080] “Ihiibitors”, “activators”, and “modulators” of metastatic colorectal cancer polynucleotide and polypeptide sequences are used to refer to activating, inhibitory, or modulating molecules or compounds identified using in vitro and in vivo assays of metastatic colorectal cancer polynucleotide and polypeptide sequences of the invention. Inhibitors are compounds that, e.g., bind to, partially or totally block activity, decrease, prevent, delay activation, inactivate, desensitize, or down regulate the activity or expression of metastatic colorectal cancer proteins of the invention, e.g., antagonists. Antisense nucleic acids may seem to inhibit expression and subsequent function of the protein. “Activators” are compounds that increase, open, activate, facilitate, enhance activation, sensitize, agonize, or up regulate metastatic colorectal cancer protein activity. Inhibitors, activators, or modulators also include genetically modified versions of metastatic colorectal cancer proteins, e.g., versions with altered activity, as well as naturally occurring and synthetic ligands, antagonists, agonists, antibodies, small chemical molecules and the like. Such assays for inhibitors and activators include, e.g., expressing the metastatic colorectal cancer protein in vitro, in cells, or cell membranes, applying putative modulator compounds, and then determining the functional effects on activity, as described above. Activators and inhibitors of metastatic colorectal cancer can also be identified by incubating metastatic colorectal cancer cells with the test compound and determining increases or decreases in the expression of 1 or more metastatic colorectal cancer proteins, e.g., 1, 2, 3, 4, 5, 10, 15, 20, 25, 30, 40, 50 or more metastatic colorectal cancer proteins, such as colorectal cancer proteins encoded by the sequences set out in Tables 1-26.  
     [0081] Samples or assays comprising metastatic colorectal cancer proteins that are treated with a potential activator, inhibitor, or modulator are compared to control samples without the inhibitor, activator, or modulator to examine the extent of inhibition. Control samples (untreated with inhibitors) are assigned a relative protein activity value of 100%. Inhibition of a polypeptide is achieved when the activity value relative to the control is about 80%, preferably 50%, more preferably 25-0%. Activation of a metastatic colorectal cancer polypeptide is achieved when the activity value relative to the control (untreated with activators) is 110%, more preferably 150%, more preferably 200-500% (i.e., two to five fold higher relative to the control), more preferably 1000-3000% higher.  
     [0082] The phrase “changes in cell growth” refers to any change in cell growth and proliferation characteristics in vitro or in vivo, such as formation of foci, anchorage independence, semi-solid or soft agar growth, changes in contact inhibition and density limitation of growth, loss of growth factor or serum requirements, changes in cell morphology, gaining or losing immortalization, gaining or losing tumor specific markers, ability to form or suppress tumors when injected into suitable animal hosts, and/or immortalization of the cell. See, e.g., Freshney,  Culture of Animal Cells a Manual of Basic Technique  pp. 231-241 (3 rd  ed. 1994).  
     [0083] “Tumor cell” refers to precancerous, cancerous, and normal cells in a tumor.  
     [0084] “Cancer cells,” “transformed” cells or “transformation” in tissue culture, refers to spontaneous or induced phenotypic changes that do not necessarily involve the uptake of new genetic material. Although transformation can arise from infection with a transforming virus and incorporation of new genomic DNA, or uptake of exogenous DNA, it can also arise spontaneously or following exposure to a carcinogen, thereby mutating an endogenous gene. Transformation is associated with phenotypic changes, such as immortalization of cells, aberrant growth control, nonmorphological changes, and/or malignancy (see, Freshney,  Culture of Animal Cells a Manual of Basic Technique  (3 rd  ed. 1994)).  
     [0085] “Antibody” refers to a polypeptide comprising a framework region from an immunoglobulin gene or fragments thereof that specifically binds and recognizes an antigen. The recognized immunoglobulin genes include the kappa, lambda, alpha, gamma, delta, epsilon, and mu constant region genes, as well as the myriad immunoglobulin variable region genes. Light chains are classified as either kappa or lambda. Heavy chains are classified as gamma, mu, alpha, delta, or epsilon, which in turn define the immunoglobulin classes, IgG, IgM, IgA, IgD and IgE, respectively. Typically, the antigen-binding region of an antibody or its functional equivalent will be most critical in specificity and affinity of binding. See Paul,  Fundamental Immunology.    
     [0086] An exemplary immunoglobulin (antibody) structural unit comprises a tetramer. Each tetramer is composed of two identical pairs of polypeptide chains, each pair having one “light” (about 25 kD) and one “heavy” chain (about 50-70 kD). The N-terminus of each chain defines a variable region of about 100 to 110 or more amino acids primarily responsible for antigen recognition. The terms variable light chain (V L ) and variable heavy chain (V H ) refer to these light and heavy chains respectively.  
     [0087] Antibodies exist, e.g., as intact immunoglobulins or as a number of well-characterized fragments produced by digestion with various peptidases. Thus, e.g., pepsin digests an antibody below the disulfide linkages in the hinge region to produce F(ab′) 2 , a dimer of Fab which itself is a light chain joined to V H -C H 1 by a disulfide bond. The F(ab′) 2  may be reduced under mild conditions to break the disulfide linkage in the hinge region, thereby converting the F(ab′)′ 2  dimer into an Fab′ monomer. The Fab′ monomer is essentially Fab with part of the hinge region (see  Fundamental Immunology  (Paul ed., 3d ed. 1993). While various antibody fragments are defined in terms of the digestion of an intact antibody, one of skill will appreciate that such fragments may be synthesized de novo either chemically or by using recombinant DNA methodology. Thus, the term antibody, as used herein, also includes antibody fragments either produced by the modification of whole antibodies, or those synthesized de novo using recombinant DNA methodologies (e.g., single chain Fv) or those identified using phage display libraries (see, e.g., McCafferty et al.,  Nature  348:552-554 (1990))  
     [0088] For preparation of antibodies, e.g., recombinant, monoclonal, or polyclonal antibodies, many technique known in the art can be used (see, e.g. Kohler &amp; Milstein,  Nature  256:495-497 (1975); Kozbor et al.,  Immunology Today  4:72 (1983); Cole et al., pp. 77-96 in  Monoclonal Antibodies and Cancer Therapy  (1985); Coligan,  Current Protocols in Immunology  (1991); Harlow &amp; Lane, Antibodies,  A Laboratory Manual  (1988); and Goding,  Monoclonal Antibodies: Principles and Practice  (2d ed. 1986)). Techniques for the production of single chain antibodies (U.S. Pat. No. 4,946,778) can be adapted to produce antibodies to polypeptides of this invention. Also, transgenic mice, or other organisms such as other mammals, may be used to express humanized antibodies. Alternatively, phage display technology can be used to identify antibodies and heteromeric Fab fragments that specifically bind to selected antigens (see, e.g., McCafferty et al.,  Nature  348:552-554 (1990); Marks et al.,  Biotechnology  10:779-783 (1992)).  
     [0089] A “chimeric antibody” is an antibody molecule in which, e.g, (a) the constant region, or a portion thereof, is altered, replaced or exchanged so that the antigen binding site (variable region) is linked to a constant region of a different or altered class, effector function and/or species, or an entirely different molecule which confers new properties to the chimeric antibody, e.g., an enzyme, toxin, hormone, growth factor, drug, etc.; or (b) the variable region, or a portion thereof, is altered, replaced or exchanged with a variable region having a different or altered antigen specificity.  
     [0090] Identification of Metastatic Colorectal Cancer-Associated Sequences  
     [0091] In one aspect, the expression levels of genes are determined in different patient samples for which diagnosis information is desired, to provide expression profiles. An expression profile of a particular sample is essentially a “fingerprint” of the state of the .sample; while two states may have any particular gene similarly expressed, the evaluation of a number of genes simultaneously allows the generation of a gene expression profile that is characteristic of the state of the cell. That is, normal tissue may be distinguished from cancerous or metastatic cancerous tissue, or metastatic cancerous tissue can be compared with tissue from surviving cancer patients. By comparing expression profiles of tissue in known different metastatic colorectal cancer states, information regarding which genes are important (including both up- and down-regulation of genes) in each of these states is obtained.  
     [0092] The identification of sequences that are differentially expressed in metastatic colorectal cancer versus non-metastatic colorectal cancer tissue allows the use of this information in a number of ways. For example, a particular treatment regime may be evaluated: does a chemotherapeutic drug act to down-regulate metastatic colorectal cancer, and thus tumor growth or recurrence, in a particular patient. Similarly, diagnosis and treatment outcomes may be done or confirmed by comparing patient samples with the known expression profiles. Metastatic tissue can also be analyzed to determine the stage of metastatic colorectal cancer in the tissue. Furthermore, these gene expression profiles (or individual genes) allow screening of drug candidates with an eye to mimicking or altering a particular expression profile; e.g., screening can be done for drugs that suppress the metastatic colorectal cancer expression profile. This may be done by making biochips comprising sets of the important metastatic colorectal cancer genes, which can then be used in these screens. PCR methods may be applied with selected primer pairs, and analysis may be of RNA or of genomic sequences. These methods can also be done on the protein basis; that is, protein expression levels of the metastatic colorectal cancer proteins can be evaluated for diagnostic purposes or to screen candidate agents. In addition, the metastatic colorectal cancer nucleic acid sequences can be administered for gene therapy purposes, including the administration of antisense nucleic acids, or the metastatic colorectal cancer proteins (including antibodies and other modulators thereof) administered as therapeutic drugs or as protein or DNA vaccines.  
     [0093] Thus the present invention provides nucleic acid and protein sequences that are differentially expressed in metastatic colorectal cancer, herein termed “metastatic colorectal cancer sequences.” As outlined below, metastatic colorectal cancer sequences include those that are up-regulated (i.e., expressed at a higher level) in metastatic colorectal cancer, as well as those that are down-regulated (i.e., expressed at a lower level). In a preferred embodiment, the metastatic colorectal cancer sequences are from humans; however, as will be appreciated by those in the art, metastatic colorectal cancer sequences from other organisms may be useful in animal models of disease and drug evaluation; thus, other metastatic colorectal cancer sequences are provided, from vertebrates, including mammals, including rodents (rats, mice, hamsters, guinea pigs, etc.), primates, farm animals (including sheep, goats, pigs, cows, horses, etc.) and pets (dogs, cats, etc.). Metastatic colorectal cancer sequences from other organisms may be obtained using the techniques outlined below.  
     [0094] Metastatic colorectal cancer sequences can include both nucleic acid and amino acid sequences. As will be appreciated by those in the art and is more fully outlined below, metastatic colorectal cancer nucleic acid sequences are useful in a variety of applications, including diagnostic applications, which will detect naturally occurring nucleic acids, as well as screening applications; e.g., biochips comprising nucleic acid probes or PCR microtiter plates with selected probes to the metastatic colorectal cancer sequences can be generated.  
     [0095] A metastatic colorectal cancer sequence can be initially identified by substantial nucleic acid and/or amino acid sequence homology to the metastatic colorectal cancer sequences outlined herein. Such homology can be based upon the overall nucleic acid or amino acid sequence, and is generally determined as outlined below, using either homology programs or hybridization conditions.  
     [0096] For identifying metastatic colorectal cancer-associated sequences, the metastatic colorectal cancer screen typically includes comparing genes identified in different tissues, e.g., normal and cancerous tissues, or tumor tissue samples from patients who have metastatic disease vs. non metastatic tissue, or tumor tissue samples from patients who have been diagnosed with Dukes stage A or B cancer but have survived vs. metastatic tissue. Other suitable tissue comparisons include comparing metastatic colorectal cancer samples with metastatic cancer samples from other cancers, such as lung, breast, other gastrointestinal cancers, prostate, ovarian, etc. Samples of, e.g., Dukes stage B survivor tissue and tissue undergoing metastasis are applied to biochips comprising nucleic acid probes. The samples are first microdissected, if applicable, and treated as is known in the art for the preparation of mRNA. Suitable biochips are commercially available, e.g., from Affymetrix. Gene expression profiles as described herein are generated and the data analyzed.  
     [0097] In one embodiment, the genes showing changes in expression as between normal and disease states are compared to genes expressed in other normal tissues, preferably normal colon, but also including, and not limited to lung, heart, brain, liver, breast, kidney, muscle, prostate, small intestine, large intestine, spleen, bone and placenta. In a preferred embodiment, those genes identified during the metastatic colorectal cancer screen that are expressed in significant amounts in other tissues are removed from the profile, although in some embodiments, this is not necessary. That is, when screening for drugs, it is usually preferable that the target be disease specific, to minimize possible side effects.  
     [0098] In a preferred embodiment, metastatic colorectal cancer sequences are those that are up-regulated in metastatic colorectal cancer; that is, the expression of these genes is higher in the metastatic tissue as compared to non-metastatic cancerous tissue or normal colon tissue (see, e.g., Tables 1-26). “Up-regulation” as used herein means, when the ratio is presented as a number greater than one, that the ratio is greater than one, preferably 1.5 or greater, more preferably 2.0 or greater. All UniGene cluster identification numbers and accession numbers herein are for the GenBank sequence database and the sequences of the accession numbers are hereby expressly incorporated by reference. GenBank is known in the art, see, e.g., Benson, DA, et al., Nucleic Acids Research 26:1-7 (1998) and http://www.ncbi.nlm.nih.gov/. Sequences are also available in other databases, e.g., European Molecular Biology Laboratory (EMBL) and DNA Database of Japan (DDBJ).  
     [0099] In another preferred embodiment, metastatic colorectal cancer sequences are those that are down-regulated in the metastatic colorectal cancer; that is, the expression of these genes is lower in metastatic tissue as compared to non-metastatic cancerous tissue or normal colon tissue (see, e.g., Tables 1-26). “Down-regulation” as used herein means, when the ratio is presented as a number greater than one, that the ratio is greater than one, preferably 1.5 or greater, more preferably 2.0 or greater, or, when the ratio is presented as a number less than one, that the ratio is less than one, preferably 0.5 or less, more preferably 0.25 or less.  
     [0100] Informatics  
     [0101] The ability to identify genes that are over or under expressed in metastatic colorectal cancer can additionally provide high-resolution, high-sensitivity datasets which can be used in the areas of diagnostics, therapeutics, drug development, pharmacogenetics, protein structure, biosensor development, and other related areas. For example, the expression profiles can be used in diagnostic or prognostic evaluation of patients with metastatic colorectal cancer. Or as another example, subcellular toxicological information can be generated to better direct drug structure and activity correlation (see Anderson,  Pharmaceutical Proteomics: Targets, Mechanism, and Function,  paper presented at the IBC Proteomics conference, Coronado, Calif. (Jun. 11-12, 1998)). Subcellular toxicological information can also be utilized in a biological sensor device to predict the likely toxicological effect of chemical exposures and likely tolerable exposure thresholds (see U.S. Pat. No. 5,811,231). Similar advantages accrue from datasets relevant to other biomolecules and bioactive agents (e.g., nucleic acids, saccharides, lipids, drugs, and the like).  
     [0102] Thus, in another embodiment, the present invention provides a database that includes at least one set of assay data. The data contained in the database is acquired, e.g., using array analysis either singly or in a library format. The database can be in substantially any form in which data can be maintained and transmitted, but is preferably an electronic database. The electronic database of the invention can be maintained on any electronic device allowing for the storage of and access to the database, such as a personal computer, but is preferably distributed on a wide area network, such as the World Wide Web.  
     [0103] The focus of the present section on databases that include peptide sequence data is for clarity of illustration only. It will be apparent to those of skill in the art that similar databases can be assembled for assay data acquired using an assay of the invention.  
     [0104] The compositions and methods for identifying and/or quantitating the relative and/or absolute abundance of a variety of molecular and macromolecular species from a biological sample undergoing metastatic colorectal cancer, i.e., the identification of metastatic colorectal cancer-associated sequences described herein, provide an abundance of information, which can be correlated with pathological conditions, predisposition to disease, drug testing, therapeutic monitoring, gene-disease causal linkages, identification of correlates of immunity and physiological status, among others. Although the data generated from the assays of the invention is suited for manual review and analysis, in a preferred embodiment, prior data processing using high-speed computers is utilized.  
     [0105] An array of methods for indexing and retrieving biomolecular information is known in the art. For example, U.S. Pat. Nos. 6,023,659 and 5,966,712 disclose a relational database system for storing biomolecular sequence information in a manner that allows sequences to be catalogued and searched according to one or more protein function hierarchies. U.S. Pat. No. 5,953,727 discloses a relational database having sequence records containing information in a format that allows a collection of partial-length DNA sequences to be catalogued and searched according to association with one or more sequencing projects for obtaining full-length sequences from the collection of partial length sequences. U.S. Pat. No. 5,706,498 discloses a gene database retrieval system for making a retrieval of a gene sequence similar to a sequence data item in a gene database based on the degree of similarity between a key sequence and a target sequence. U.S. Pat. No. 5,538,897 discloses a method using mass spectroscopy fragmentation patterns of peptides to identify amino acid sequences in computer databases by comparison of predicted mass spectra with experimentally-derived mass spectra using a closeness-of-fit measure. U.S. Pat. No. 5,926,818 discloses a multi-dimensional database comprising a functionality for multi-dimensional data analysis described as on-line analytical processing (OLAP), which entails the consolidation of projected and actual data according to more than one consolidation path or dimension. U.S. Pat. No. 5,295,261 reports a hybrid database structure in which the fields of each database record are divided into two classes, navigational and informational data, with navigational fields stored in a hierarchical topological map which can be viewed as a tree structure or as the merger of two or more such tree structures.  
     [0106] See also Mount et al.,  Bioinformatics  (2001);  Biological Sequence Analysis: Probabilistic Models of Proteins and Nucleic Acids  (Durbin et al., eds., 1999);  Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins  (Baxevanis &amp; Oeullette eds., 1998)); Rashidi &amp; Buehler,  Bioinformatics: Basic Applications in Biological Science and Medicine  (1999);  Introduction to Computational Molecular Biology  (Setubal et al., eds 1997);  Bioinformatics: Methods and Protocols  (Misener &amp; Krawetz, eds, 2000);  Bioinformatics: Sequence, Structure, and Databanks: A Practical Approach  (Higgins &amp; Taylor, eds., 2000); Brown,  Bioinformatics: A Biologist&#39;s Guide to Biocomputing and the Internet  (2001); Han &amp; Kamber,  Data Mining: Concepts and Techniques  (2000); and Waterman,  Introduction to Computational Biology: Maps, Sequences, and Genomes  (1995).  
     [0107] The present invention provides a computer database comprising a computer and software for storing in computer-retrievable form assay data records cross-tabulated, e.g., with data specifying the source of the target-containing sample from which each sequence specificity record was obtained.  
     [0108] In an exemplary embodiment, at least one of the sources of target-containing sample is from a control tissue sample known to be free of pathological disorders. In a variation, at least one of the sources is a known pathological tissue specimen, e.g., a neoplastic lesion or another tissue specimen to be analyzed for metastatic colorectal cancer. In another variation, the assay records cross-tabulate one or more of the following parameters for each target species in a sample: (1) a unique identification code, which can include, e.g., a target molecular structure and/or characteristic separation coordinate (e.g., electrophoretic coordinates); (2) sample source; and (3) absolute and/or relative quantity of the target species present in the sample.  
     [0109] The invention also provides for the storage and retrieval of a collection of target data in a computer data storage apparatus, which can include magnetic disks, optical disks, magneto-optical disks, DRAM, SRAM, SGRAM, SDRAM, RDRAM, DDR RAM, magnetic bubble memory devices, and other data storage devices, including CPU registers and on-CPU data storage arrays. Typically, the target data records are stored as a bit pattern in an array of magnetic domains on a magnetizable medium or as an array of charge states or transistor gate states, such as an array of cells in a DRAM device (e.g., each cell comprised of a transistor and a charge storage area, which may be on the transistor). In one embodiment, the invention provides such storage devices, and computer systems built therewith, comprising a bit pattern encoding a protein expression fingerprint record comprising unique identifiers for at least 10 target data records cross-tabulated with target source.  
     [0110] When the target is a peptide or nucleic acid, the invention preferably provides a method for identifying related peptide or nucleic acid sequences, comprising performing a computerized comparison between a peptide or nucleic acid sequence assay record stored in or retrieved from a computer storage device or database and at least one other sequence. The comparison can include a sequence analysis or comparison algorithm or computer program embodiment thereof (e.g., FASTA, TFASTA, GAP, BESTFIT) and/or the comparison may be of the relative amount of a peptide or nucleic acid sequence in a pool of sequences determined from a polypeptide or nucleic acid sample of a specimen.  
     [0111] The invention also preferably provides a magnetic disk, such as an IBM-compatible (DOS, Windows, Windows95/98/2000, Windows NT, OS/2) or other format (e.g., Linux, SunOS, Solaris, AIX, SCO Unix, VMS, MV, Macintosh, etc.) floppy diskette or hard (fixed, Winchester) disk drive, comprising a bit pattern encoding data from an assay of the invention in a file format suitable for retrieval and processing in a computerized sequence analysis, comparison, or relative quantitation method.  
     [0112] The invention also provides a network, comprising a plurality of computing devices linked via a data link, such as an Ethernet cable (coax or 10BaseT), telephone line, ISDN line, wireless network, optical fiber, or other suitable signal transmission medium, whereby at least one network device (e.g., computer, disk array, etc.) comprises a pattern of magnetic domains (e.g., magnetic disk) and/or charge domains (e.g., an array of DRAM cells) composing a bit pattern encoding data acquired from an assay of the invention.  
     [0113] The invention also provides a method for transmitting assay data that includes generating an electronic signal on an electronic communications device, such as a modem, ISDN terminal adapter, DSL, cable modem, ATM switch, or the like, wherein the signal includes (in native or encrypted format) a bit pattern encoding data from an assay or a database comprising a plurality of assay results obtained by the method of the invention.  
     [0114] In a preferred embodiment, the invention provides a computer system for comparing a query target to a database containing an array of data structures, such as an assay result obtained by the method of the invention, and ranking database targets based on the degree of identity and gap weight to the target data. A central processor is preferably initialized to load and execute the computer program for alignment and/or comparison of the assay results. Data for a query target is entered into the central processor via an I/O device. Execution of the computer program results in the central processor retrieving the assay data from the data file, which comprises a binary description of an assay result.  
     [0115] The target data or record and the computer program can be transferred to secondary memory, which is typically random access memory (e.g., DRAM, SRAM, SGRAM, or SDRAM). Targets are ranked according to the degree of correspondence between a selected assay characteristic (e.g., binding to a selected affinity moiety) and the same characteristic of the query target and results are output via an I/O device. For example, a central processor can be a conventional computer (e.g., Intel Pentium, PowerPC, Alpha, PA-8000, SPARC, MIPS 4400, MIPS 10000, VAX, etc.); a program can be a commercial or public domain molecular biology software package (e.g., UWGCG Sequence Analysis Software, Darwin); a data file can be an optical or magnetic disk, a data server, a memory device (e.g., DRAM, SRAM, SGRAM, SDRAM, EPROM, bubble memory, flash memory, etc.); an I/O device can be a terminal comprising a video display and a keyboard, a modem, an ISDN terminal adapter, an Ethernet port, a punched card reader, a magnetic strip reader, or other suitable I/O device.  
     [0116] The invention also preferably provides the use of a computer system, such as that described above, which comprises: (1) a computer; (2) a stored bit pattern encoding a collection of peptide sequence specificity records obtained by the methods of the invention, which may be stored in the computer; (3) a comparison target, such as a query target; and (4) a program for alignment and comparison, typically with rank-ordering of comparison results on the basis of computed similarity values.  
     [0117] Characteristics of Metastatic Colorectal Cancer-Associated Proteins  
     [0118] Metastatic colorectal cancer proteins of the present invention may be classified as secreted proteins, transmembrane proteins or intracellular proteins. In one embodiment, the metastatic colorectal cancer protein is an intracellular protein. Intracellular proteins may be found in the cytoplasm and/or in the nucleus and/or in the organelles. Proteins containing one or more transmembrane domains that exclusively reside in organelles are also considered intracellular proteins. Intracellular proteins are involved in all aspects of cellular function and replication (including, e.g., signaling pathways); aberrant expression of such proteins often results in unregulated or disregulated cellular processes (see, e.g.,  Molecular Biology of the Cell  (Alberts, ed., 3rd ed., 1994). For example, many intracellular proteins have enzymatic activity such as protein kinase activity, protein phosphatase activity, protease activity, nucleotide cyclase activity, polymerase activity and the like. Intracellular proteins also serve as docking proteins that are involved in organizing complexes of proteins, or targeting proteins to various subcellular localizations, and are involved in maintaining the structural integrity of organelles.  
     [0119] An increasingly appreciated concept in characterizing proteins is the presence in the proteins of one or more motifs for which defined functions have been attributed. In addition to the highly conserved sequences found in the enzymatic domain of proteins, highly conserved sequences have been identified in proteins that are involved in protein-protein interaction. For example, Src-homology-2 (SH2) domains bind tyrosine-phosphorylated targets in a sequence dependent manner. PTB domains, which are distinct from SH2 domains, also bind tyrosine phosphorylated targets. SH3 domains bind to proline-rich targets. In addition, PH domains, tetratricopeptide repeats and WD domains to name only a few, have been shown to mediate protein-protein interactions. Some of these may also be involved in binding to phospholipids or other second messengers. As will be appreciated by one of ordinary skill in the art, these motifs can be identified on the basis of primary sequence; thus, an analysis of the sequence of proteins may provide insight into both the enzymatic potential of the molecule and/or molecules with which the protein may associate. One useful database is Pfam (protein families), which is a large collection of multiple sequence alignments and hidden Markov models covering many common protein domains. Versions are available via the internet from Washington University in St. Louis, the Sanger Center in England, and the Karolinska Institute in Sweden (see, e.g., Bateman et al.,  Nuc. Acids Res.  28:263-266 (2000); Sonnhammer et al.,  Proteins  28:405-420 (1997); Bateman et al.,  Nuc. Acids Res.  27:260-262 (1999); and Sonnharnmer et al.,  Nuc. Acids Res.  26:320-322-(1998)).  
     [0120] In another embodiment, the metastatic colorectal cancer sequences are transmembrane proteins. Transmembrane proteins are molecules that span a phospholipid bilayer of a cell. They may have an intracellular domain, an extracellular domain, or both. The intracellular domains of such proteins may have a number of functions including those already described for intracellular proteins. For example, the intracellular domain may have enzymatic activity and/or may serve as a binding site for additional proteins. Frequently the intracellular domain of transmembrane proteins serves both roles. For example certain receptor tyrosine kinases have both protein kinase activity and SH2 domains. In addition, autophosphorylation of tyrosines on the receptor molecule itself, creates binding sites for additional SH2 domain containing proteins.  
     [0121] Transmembrane proteins may contain from one to many transmembrane domains. For example, receptor tyrosine kinases, certain cytokine receptors, receptor guanylyl cyclases and receptor serine/threonine protein kinases contain a single transmembrane domain. However, various other proteins including channels, pumps, and adenylyl cyclases contain numerous transmembrane domains. Many important cell surface receptors such as G protein coupled receptors (GPCRs) are classified as “seven transmembrane domain” proteins, as they contain 7 membrane spanning regions. Characteristics of transmembrane domains include approximately 20 consecutive hydrophobic amino acids that may be followed by charged amino acids. Therefore, upon analysis of the amino acid sequence of a particular protein, the localization and number of transmembrane domains within the protein may be predicted (see, e.g. PSORT web site http://psort.nibb.ac.jp/).  
     [0122] The extracellular domains of transmembrane proteins are diverse; however, conserved motifs are found repeatedly among various extracellular domains. Conserved structure and/or functions have been ascribed to different extracellular motifs. Many extracellular domains are involved in binding to other molecules. In one aspect, extracellular domains are found on receptors. Factors that bind the receptor domain include circulating ligands, which may be peptides, proteins, or small molecules such as adenosine and the like. For example, growth factors such as EGF, FGF and PDGF are circulating growth factors that bind to their cognate receptors to initiate a variety of cellular responses. Other factors include cytokines, mitogenic factors, hormones, neurotrophic factors and the like. Extracellular domains also bind to cell-associated molecules. In this respect, they mediate cell-cell interactions. Cell-associated ligands can be tethered to the cell, e.g., via a glycosylphosphatidylinositol (GPI) anchor, or may themselves be transmembrane proteins. Extracellular domains also associate with the extracellular matrix and contribute to the maintenance of the cell structure.  
     [0123] Metastatic colorectal cancer proteins that are transmembrane are particularly preferred in the present invention as they are readily accessible targets for extracellular immunotherapeutics, as are described herein. In addition, as outlined below, transmembrane proteins can be also useful in imaging modalities. Antibodies may be used to label such readily accessible proteins in situ or in histological analysis. Alternatively, antibodies can also label intracellular proteins, in which case analytical samples are typically permeablized to provide access to intracellular proteins.  
     [0124] It will also be appreciated by those in the art that a transmembrane protein can be made soluble by removing transmembrane sequences, e.g., through recombinant methods. Furthermore, transmembrane proteins that have been made soluble can be made to be secreted through recombinant means by adding an appropriate signal sequence.  
     [0125] In another embodiment, the metastatic colorectal cancer proteins are secreted proteins; the secretion of which can be either constitutive or regulated. These proteins have a signal peptide or signal sequence that targets the molecule to the secretory pathway. Secreted proteins are involved in numerous physiological events; by virtue of their circulating nature, they often serve to transmit signals to various other cell types. The secreted protein may function in an autocrine manner (acting on the cell that secreted the factor), a paracrine manner (acting on cells in close proximity to the cell that secreted the factor) or an endocrine manner (acting on cells at a distance). Thus secreted molecules find use in modulating or altering numerous aspects of physiology. Metastatic colorectal cancer proteins that are secreted proteins are particularly preferred in the present invention as they serve as good targets for diagnostic markers, e.g., for blood, plasma, serum, or stool tests.  
     [0126] Use of Metastatic Colorectal Cancer Nucleic Acids  
     [0127] As described above, metastatic colorectal cancer sequence is initially identified by substantial nucleic acid and/or amino acid sequence homology or linkage to the metastatic colorectal cancer sequences outlined herein. Such homology can be based upon the overall nucleic acid or amino acid sequence, and is generally determined as outlined below, using either homology programs or hybridization conditions. Typically, linked sequences on a mRNA are found on the same molecule. The metastatic colorectal cancer nucleic acid sequences of the invention, e.g., the sequences in Tables 1-26, can be fragments of larger genes, i.e., they are nucleic acid segments. “Genes” in this context includes coding regions, non-coding regions, and mixtures of coding and non-coding regions. Accordingly, as will be appreciated by those in the art, using the sequences provided herein, extended sequences, in either direction, of the metastatic colorectal cancer genes can be obtained, using techniques well known in the art for cloning either longer sequences or the full length sequences; see Ausubel, et al., supra. Much can be done by informatics and many sequences can be clustered to include multiple sequences corresponding to a single gene, e.g., systems such as UniGene (see, http://www.ncbi.nlm.nih.gov/unigene/).  
     [0128] Once the metastatic colorectal cancer nucleic acid is identified, it can be cloned and, if necessary, its constituent parts recombined to form the entire metastatic colorectal cancer nucleic acid coding regions or the entire mRNA sequence. Once isolated from its natural source, e.g., contained within a plasmid or other vector or excised therefrom as a linear nucleic acid segment, the recombinant metastatic colorectal cancer nucleic acid can be further-used as a probe to identify and isolate other metastatic colorectal cancer nucleic acids, e.g., extended coding regions. It can also be used as a “precursor” nucleic acid to make modified or variant metastatic colorectal cancer nucleic acids and proteins.  
     [0129] The metastatic colorectal cancer nucleic acids of the present invention are used in several ways. In a first embodiment, nucleic acid probes to the metastatic colorectal cancer nucleic acids are made and attached to biochips to be used in screening and diagnostic methods, as outlined below, or for administration, e.g., for gene therapy, vaccine, and/or antisense applications. Alternatively, the metastatic colorectal cancer nucleic acids that include coding regions of metastatic colorectal cancer proteins can be put into expression vectors for the expression of metastatic colorectal cancer proteins, again for screening purposes or for administration to a patient.  
     [0130] In a preferred embodiment, nucleic acid probes to metastatic colorectal cancer nucleic acids (both the nucleic acid sequences outlined in the figures and/or the complements thereof) are made. The nucleic acid probes attached to the biochip are designed to be substantially complementary to the metastatic colorectal cancer nucleic acids, i.e. the target sequence (either the target sequence of the sample or to other probe sequences, e.g., in sandwich assays), such that hybridization of the target sequence and the probes of the present invention occurs. As outlined below, this complementarity need not be perfect; there may be any number of base pair mismatches which will interfere with hybridization between the target sequence and the single stranded nucleic acids of the present invention. However, if the number of mutations is so great that no hybridization can occur under even the least stringent of hybridization conditions, the sequence is not a complementary target sequence. Thus, by “substantially complementary” herein is meant that the probes are sufficiently complementary to the target sequences to hybridize under appropriate reaction conditions, particularly high stringency conditions, as outlined herein.  
     [0131] A nucleic acid probe is generally single stranded but can be partially single and partially double stranded. The strandedness of the probe is dictated by the structure, composition, and properties of the target sequence. In general, the nucleic acid probes range from about 8 to about 100 bases long, with from about 10 to about 80 bases being preferred, and from about 30 to about 50 bases being particularly preferred. That is, generally complements of ORFs or whole genes are not used. In some embodiments, nucleic acids of lengths up to hundreds of bases can be used.  
     [0132] In a preferred embodiment, more than one probe per sequence is used, with either overlapping probes or probes to different sections of the target being used. That is, two, three, four or more probes, with three being preferred, are used to build in a redundancy for a particular target. The probes can be overlapping (i.e., have some sequence in common), or separate. In some cases, PCR primers may be used to amplify signal for higher sensitivity.  
     [0133] As will be appreciated by those in the art, nucleic acids can be attached or immobilized to a solid support in a wide variety of ways. By “immobilized” and grammatical equivalents herein is meant the association or binding between the nucleic acid probe and the solid support is sufficient to be stable under the conditions of binding, washing, analysis, and removal as outlined below. The binding can typically be covalent or non-covalent. By “non-covalent binding” and grammatical equivalents herein is typically meant one or more of electrostatic, hydrophilic, and hydrophobic interactions. Included in non-covalent binding is the covalent attachment of a molecule, such as, streptavidin to the support and the non-covalent binding of the biotinylated probe to the streptavidin. By “covalent binding” and grammatical equivalents herein is meant that the two moieties, the solid support and the probe, are attached by at least one bond, including sigma bonds, pi bonds and coordination bonds. Covalent bonds can be formed directly between the probe and the solid support or can be formed by a cross linker or by inclusion of a specific reactive group on either the solid support or the probe or both molecules. Immobilization may also involve a combination of covalent and non-covalent interactions.  
     [0134] In general, the probes are attached to a biochip in a wide variety of ways, as will be appreciated by those in the art. As described herein, the nucleic acids can either be synthesized first, with subsequent attachment to the biochip, or can be directly synthesized on the biochip.  
     [0135] The biochip comprises a suitable solid substrate. By “substrate” or “solid support” or other grammatical equivalents herein is meant a material that can be modified to contain discrete individual sites appropriate for the attachment or association of the nucleic acid probes and is amenable to at least one detection method. As will be appreciated by those in the art, the number of possible substrates are very large, and include, but are not limited to, glass and modified or functionalized glass, plastics (including acrylics, polystyrene and copolymers of styrene and other materials, polypropylene, polyethylene, polybutylene, polyurethanes, Teflon, etc.), polysaccharides, nylon or nitrocellulose, resins, silica or silica-based materials including silicon and modified silicon, carbon, metals, inorganic glasses, plastics, etc. In general, the substrates allow optical detection and do not appreciably fluoresce. A preferred substrate is described in copending application entitled Reusable Low Fluorescent Plastic Biochip, U.S. application Ser. No. 09/270,214, filed Mar. 15, 1999, herein incorporated by reference in its entirety.  
     [0136] Generally the substrate is planar, although as will be appreciated by those in the art, other configurations of substrates may be used as well. For example, the probes may be placed on the inside surface of a tube, for flow-through sample analysis to minimize sample volume. Similarly, the substrate may be flexible, such as a flexible foam, including closed cell foams made of particular plastics.  
     [0137] In a preferred embodiment, the surface of the biochip and the probe may be derivatized with chemical functional groups for subsequent attachment of the two. Thus, e.g., the biochip is derivatized with a chemical functional group including, but not limited to, amino groups, carboxy groups, oxo groups and thiol groups, with amino groups being particularly preferred. Using these functional groups, the probes can be attached using functional groups on the probes. For example, nucleic acids containing amino groups can be attached to surfaces comprising amino groups, e.g., using linkers as are known in the art; e.g., homo-or hetero-bifunctional linkers as are well known (see 1994 Pierce Chemical Company catalog, technical section on cross-linkers, pages 155-200). In addition, in some cases, additional linkers, such as alkyl groups (including substituted and heteroalkyl groups) may be used.  
     [0138] In this embodiment, oligonucleotides are synthesized as is known in the art, and then attached to the surface of the solid support. As will be appreciated by those skilled in the art, either the 5′ or 3′ terminus may be attached to the solid support, or attachment may be via an internal nucleoside.  
     [0139] In another embodiment, the immobilization to the solid support may be very strong, yet non-covalent. For example, biotinylated oligonucleotides can be made, which bind to surfaces covalently coated with streptavidin, resulting in attachment.  
     [0140] Alternatively, the oligonucleotides may be synthesized on the surface, as is known in the art. For example, photoactivation techniques utilizing photopolymerization compounds and techniques are used. In a preferred embodiment, the nucleic acids can be synthesized in situ, using well known photolithographic techniques, such as those described in WO 95/25116; WO 95/35505; U.S. Pat. Nos. 5,700,637 and 5,445,934; and references cited within, all of which are expressly incorporated by reference; these methods of attachment form the basis of the Affimetrix GeneChip™ technology.  
     [0141] Often, amplification-based assays are performed to measure the expression level of metastatic colorectal cancer-associated sequences. These assays are typically performed in conjunction with reverse transcription. In such assays, a metastatic colorectal cancer-associated nucleic acid sequence acts as a template in an amplification reaction (e.g., Polymerase Chain Reaction, or PCR). In a quantitative amplification, the amount of amplification product will be proportional to the amount of template in the original sample. Comparison to appropriate controls provides a measure of the amount of metastatic colorectal cancer-associated RNA. Methods of quantitative amplification are well known to those of skill in the art. Detailed protocols for quantitative PCR are provided, e.g., in Innis et al.,  PCR Protocols, A Guide to Methods and Applications  (1990).  
     [0142] In some embodiments, a TaqMan based assay is used to measure expression. TaqMan based assays use a fluorogenic oligonucleotide probe that contains a 5′ fluorescent dye and a 3′ quenching agent. The probe hybridizes to a PCR product, but cannot itself be extended due to a blocking agent at the 3′ end. When the PCR product is amplified in subsequent cycles, the 5′ nuclease activity of the polymerase, e.g., AmpliTaq, results in the cleavage of the TaqMan probe. This cleavage separates the 5′ fluorescent dye and the 3′ quenching agent, thereby resulting in an increase in fluorescence as a function of amplification (see, e.g., literature provided by Perkin-Elmer, e.g., www2.perkin-elmer.com).  
     [0143] Other suitable amplification methods include, but are not limited to, ligase chain reaction (LCR) (see Wu &amp; Wallace,  Genomics  4:560 (1989), Landegren et al.,  Science  241:1077 (1988), and Barringer et al.,  Gene  89:117 (1990)), transcription amplification (Kwoh et al.,  Proc. Natl. Acad. Sci. USA  86:1173 (1989)), self-sustained sequence replication (Guatelli et al.,  Proc. Nat. Acad. Sci. USA  87:1874 (1990)), dot PCR, and linker adapter PCR, etc.  
     [0144] Expression of Metastatic Colorectal Cancer Proteins From Nucleic Acids  
     [0145] In a preferred embodiment, metastatic colorectal cancer nucleic acids, e.g., encoding metastatic colorectal cancer proteins, are used to make a variety of expression vectors to express metastatic colorectal cancer proteins which can then be used in screening assays, as described below. Expression vectors and recombinant DNA technology are well known to those of skill in the art (see, e.g., Ausubel, supra, and  Gene Expression Systems  (Fernandez &amp; Hoeffler, eds, 1999)) and are used to express proteins. The expression vectors may be either self-replicating extrachromosomal vectors or vectors which integrate into a host genome. Generally, these expression vectors include transcriptional and translational regulatory nucleic acid operably linked to the nucleic acid encoding the metastatic colorectal cancer protein. The term “control sequences” refers to DNA sequences used for the expression of an operably linked coding sequence in a particular host organism. Control sequences that are suitable for prokaryotes, e.g., include a promoter, optionally an operator sequence, and a ribosome binding site. Eukaryotic cells are known to utilize promoters, polyadenylation signals, and enhancers.  
     [0146] Nucleic acid is “operably linked” when it is placed into a functional relationship with another nucleic acid sequence. For example, DNA for a presequence or secretory leader is operably linked to DNA for a polypeptide if it is expressed as a preprotein that participates in the secretion of the polypeptide; a promoter or enhancer is operably linked to a coding sequence if it affects the transcription of the sequence; or a ribosome binding site is operably linked to a coding sequence if it is positioned so as to facilitate translation. Generally, “operably linked” means that the DNA sequences being linked are contiguous, and, in the case of a secretory leader, contiguous and in reading phase. However, enhancers do not have to be contiguous. Linking is typically accomplished by ligation at convenient restriction sites. If such sites do not exist, synthetic oligonucleotide adaptors or linkers are used in accordance with conventional practice. Transcriptional and translational regulatory nucleic acid will generally be appropriate to the host cell used to express the metastatic colorectal cancer protein. Numerous types of appropriate expression vectors, and suitable regulatory sequences are known in the art for a variety of host cells.  
     [0147] In general, transcriptional and translational regulatory sequences may include, but are not limited to, promoter sequences, ribosomal binding sites, transcriptional start and stop sequences, translational start and stop sequences, and enhancer or activator sequences. In a preferred embodiment, the regulatory sequences include a promoter and transcriptional start and stop sequences.  
     [0148] Promoter sequences encode either constitutive or inducible promoters. The promoters may be either naturally occurring promoters or hybrid promoters. Hybrid promoters, which combine elements of more than one promoter, are also known in the art, and are useful in the present invention.  
     [0149] In addition, an expression vector may comprise additional elements. For example, the expression vector may have two replication systems, thus allowing it to be maintained in two organisms, e.g., in mammalian or insect cells for expression and in a procaryotic host for cloning and amplification. Furthermore, for integrating expression vectors, the expression vector contains at least one sequence homologous to the host cell genome, and preferably two homologous sequences which flank the expression construct. The integrating vector may be directed to a specific locus in the host cell by selecting the appropriate homologous sequence for inclusion in the vector. Constructs for integrating vectors are well known in the art (e.g., Fernandez &amp; Hoeffler, supra).  
     [0150] In addition, in a preferred embodiment, the expression vector contains a selectable marker gene to allow the selection of transformed host cells. Selection genes are well known in the art and will vary with the host cell used.  
     [0151] The metastatic colorectal cancer proteins of the present invention are produced by culturing a host cell transformed with an expression vector containing nucleic acid encoding a metastatic colorectal cancer protein, under the appropriate conditions to induce or cause expression of the metastatic colorectal cancer protein. Conditions appropriate for metastatic colorectal cancer protein expression will vary with the choice of the expression vector and the host cell, and will be easily ascertained by one skilled in the art through routine experimentation or optimization. For example, the use of constitutive promoters in the expression vector will require optimizing the growth and proliferation of the host cell, while the use of an inducible promoter requires the appropriate growth conditions for induction. In addition, in some embodiments, the timing of the harvest is important. For example, the baculoviral systems used in insect cell expression are lytic viruses, and thus harvest time selection can be crucial for product yield.  
     [0152] Appropriate host cells include yeast, bacteria, archaebacteria, fungi, and insect and animal cells, including mammalian cells. Of particular interest are  Saccharomyces cerevisiae  and other yeasts,  E. coli, Bacillus subtilis , Sf9 cells, C129 cells, 293 cells, Neurospora, BHK, CHO, COS, HeLa cells, HLVEC (human umbilical vein endothelial cells), THP1 cells (a macrophage cell line) and various other human cells and cell lines.  
     [0153] In a preferred embodiment, the metastatic colorectal cancer proteins are expressed in mammalian cells. Mammalian expression systems are also known in the art, and include retroviral and adenoviral systems. Of particular use as mammalian promoters are the promoters from mammalian viral genes, since the viral genes are often highly expressed and have a broad host range. Examples include the SV40 early promoter, mouse mammary tumor virus LTR promoter, adenovirus major late promoter, herpes simplex virus promoter, and the CMV promoter (see, e.g., Fernandez &amp; Hoeffler, supra). Typically, transcription termination and polyadenylation sequences recognized by mammalian cells are regulatory regions located 3′ to the translation stop codon and thus, together with the promoter elements, flank the coding sequence. Examples of transcription terminator and polyadenylation signals include those derived form SV40.  
     [0154] The methods of introducing exogenous nucleic acid into mammalian hosts, as well as other hosts, is well known in the art, and will vary with the host cell used. Techniques include dextran-mediated transfection, calcium phosphate precipitation, polybrene mediated transfection, protoplast fusion, electroporation, viral infection, encapsulation of the polynucleotide(s) in liposomes, and direct microinjection of the DNA into nuclei.  
     [0155] In a preferred embodiment, metastatic colorectal cancer proteins are expressed in bacterial systems. Promoters from bacteriophage may also be used and are known in the art. In addition, synthetic promoters and hybrid promoters are also useful; e.g., the tac promoter is a hybrid of the trp and lac promoter sequences. Furthermore, a bacterial promoter can include naturally occurring promoters of non-bacterial origin that have the ability to bind bacterial RNA polymerase and initiate transcription. In addition to a functioning promoter sequence, an efficient ribosome binding site is desirable. The expression vector may also include a signal peptide sequence that provides for secretion of the metastatic colorectal cancer protein in bacteria. The protein is either secreted into the growth media (gram-positive bacteria) or into the periplasmic space, located between the inner and outer membrane of the cell (gram-negative bacteria). The bacterial expression vector may also include a selectable marker gene to allow for the selection of bacterial strains that have been transformed. Suitable selection genes include genes which render the bacteria resistant to drugs such as ampicillin, chloramphenicol, erythromycin, kanamycin, neomycin and tetracycline. Selectable markers also include biosynthetic genes, such as those in the histidine, tryptophan and leucine biosynthetic pathways. These components are assembled into expression vectors. Expression vectors for bacteria are well known in the art, and include vectors for  Bacillus subtilis, E. coli, Streptococcus cremoris,  and  Streptococcus lividans,  among others (e.g., Fernandez &amp; Hoeffler, supra). The bacterial expression vectors are transformed into bacterial host cells using techniques well known in the art, such as calcium chloride treatment, electroporation, and others.  
     [0156] In one embodiment, metastatic colorectal cancer proteins are produced in insect cells. Expression vectors for the transformation of insect cells, and in particular, baculovirus-based expression vectors, are well known in the art.  
     [0157] In a preferred embodiment, metastatic colorectal cancer protein is produced in yeast cells. Yeast expression systems are well known in the art, and include expression vectors for  Saccharomyces cerevisiae, Candida albicans  and  C. maltosa, Hansenula polymorpha, Kluyveromyces fragilis  and  K. lactis, Pichia guillerimondii  and  P. pastoris, Schizosaccharomyces pombe , and  Yarrowia lipolytica.    
     [0158] The metastatic colorectal cancer protein may also be made as a fusion protein, using techniques well known in the art. Thus, e.g., for the creation of monoclonal antibodies, if the desired epitope is small, the metastatic colorectal cancer protein may be fused to a carrier protein to form an immunogen. Alternatively, the metastatic colorectal cancer protein may be made as a fusion protein to increase expression for affinity purification purposes, or for other reasons. For example, when the metastatic colorectal cancer protein is a metastatic colorectal cancer peptide, the nucleic acid encoding the peptide may be linked to other nucleic acid for expression purposes.  
     [0159] In a preferred embodiment, the metastatic colorectal cancer protein is purified or isolated after expression. Metastatic colorectal cancer proteins may be isolated or purified in a variety of appropriate ways. Standard purification methods include electrophoretic, molecular, immunological and chromatographic techniques, including ion exchange, hydrophobic, affinity, and reverse-phase HPLC chromatography, and chromatofocusing. For example, the metastatic colorectal cancer protein may be purified using a standard anti-metastatic colorectal cancer protein antibody column. Ultrafiltration and diafiltration techniques, in conjunction with protein concentration, are also useful. For general guidance in suitable purification techniques, see Scopes,  Protein Purification  (1982). The degree of purification necessary will vary depending on the use of the metastatic colorectal cancer protein. In some instances no purification will be necessary.  
     [0160] Once expressed and purified if necessary, the metastatic colorectal cancer proteins and nucleic acids are useful in a number of applications. They may be used as immunoselection reagents, as vaccine reagents, as screening agents, etc.  
     [0161] Variants of Metastatic Colorectal Cancer Proteins  
     [0162] In one embodiment, the metastatic colorectal cancer proteins are derivative or variant metastatic colorectal cancer proteins as compared to the wild-type sequence. That is, as outlined more fully below, the derivative metastatic colorectal cancer peptide will often contain at least one amino acid substitution, deletion or insertion, with amino acid substitutions being particularly preferred. The amino acid substitution, insertion or deletion may occur at a particular residue within the metastatic colorectal cancer peptide.  
     [0163] Also included within one embodiment of metastatic colorectal cancer proteins of the present invention are amino acid sequence variants. These variants typically fall into one or more of three classes: substitutional, insertional or deletional variants. These variants ordinarily are prepared by site specific mutagenesis of nucleotides in the DNA encoding the metastatic colorectal cancer protein, using cassette or PCR mutagenesis or other techniques, to produce DNA encoding the variant, and thereafter expressing the DNA in recombinant cell culture as outlined above. However, variant metastatic colorectal cancer protein fragments having up to about 100-150 residues may be prepared by in vitro synthesis. Amino acid sequence variants are characterized by the predetermined nature of the variation, a feature that sets them apart from naturally occurring allelic or interspecies variation of the metastatic colorectal cancer protein amino acid sequence. The variants typically exhibit the same qualitative biological activity as the naturally occurring analogue, although variants can also be selected which have modified characteristics as will be more fully outlined below.  
     [0164] While the site or region for introducing an amino acid sequence variation is often predetermined, the mutation per se need not be predetermined. For example, in order to optimize the performance of a mutation at a given site, random mutagenesis may be conducted at the target codon or region and the expressed metastatic colorectal cancer variants screened for the optimal combination of desired activity. Techniques exist for making substitution mutations at predetermined sites in DNA having a known sequence, e.g., M13 primer mutagenesis and PCR mutagenesis. Screening of the mutants is done using assays of metastatic colorectal cancer protein activities.  
     [0165] Amino acid substitutions are typically of single residues; insertions usually will be on the order of from about 1 to 20 amino acids, although considerably larger insertions may be occasionally tolerated. Deletions range from about 1 to about 20 residues, although in some cases deletions may be much larger.  
     [0166] Substitutions, deletions, insertions or any combination thereof may be used to arrive at a final derivative. Generally these changes are done on a few amino acids to minimize the alteration of the molecule. Larger changes may be tolerated in certain circumstances. When small alterations in the characteristics of a metastatic colorectal cancer protein are desired, substitutions are generally made in accordance with the amino acid substitution chart provided in the definition section.  
     [0167] Variants typically exhibit the same qualitative biological activity and will elicit the same immune response as the naturally-occurring analog, although variants also are selected to modify the characteristics of the metastatic colorectal cancer proteins as needed. Alternatively, the variant may be designed or reorganized such that the biological activity of the metastatic colorectal cancer protein is altered. For example, glycosylation sites may be altered or removed.  
     [0168] Covalent modifications of metastatic colorectal cancer polypeptides are included within the scope of this invention. One type of covalent modification includes reacting targeted amino acid residues of a metastatic colorectal cancer polypeptide with an organic derivatizing agent that is capable of reacting with selected side chains or the N-or C-terminal residues of a metastatic colorectal cancer polypeptide. Derivatization with bifunctional agents is useful, for instance, for crosslinking metastatic colorectal cancer polypeptides to a water-insoluble support matrix or surface for use in the method for purifying anti-metastatic colorectal cancer polypeptide antibodies or screening assays, as is more fully described below. Commonly used crosslinking agents include, e.g., 1,1-bis(diazoacetyl)-2-phenylethane, glutaraldehyde, N-hydroxysuccinimide esters, e.g., esters with 4-azidosalicylic acid, homobifunctional imidoesters, including disuccinimidyl esters such as 3,3′-dithiobis(succinimidylpropionate), bifunctional maleimides such as bis-N-maleimido-1,8-octane and agents such as methyl-3-((p-azidophenyl)dithio)propioimidate.  
     [0169] Other modifications include deamidation of glutaminyl and asparaginyl residues to the corresponding glutamyl and aspartyl residues, respectively, hydroxylation of proline and lysine, phosphorylation of hydroxyl groups of seryl, threonyl or tyrosyl residues, methylation of the γ-amino groups of lysine, arginine, and histidine side chains (Creighton,  Proteins: Structure and Molecular Properties,  pp. 79-86 (1983)), acetylation of the N-terminal amine, and amidation of any C-terminal carboxyl group.  
     [0170] Another type of covalent modification of the metastatic colorectal cancer polypeptide encompassed by this invention is an altered native glycosylation pattern of the polypeptide. “Altering the native glycosylation pattern” is intended herein to mean adding to or deleting one or more carbohydrate moieties of a native sequence metastatic colorectal cancer polypeptide. Glycosylation patterns can be altered in many ways. For example the use of different cell types to express metastatic colorectal cancer-associated sequences can result in different glycosylation patterns.  
     [0171] Addition of glycosylation sites to metastatic colorectal cancer polypeptides may also be accomplished by altering the amino acid sequence thereof. The alteration may be made, e.g., by the addition of, or substitution by, one or more serine or threonine residues to the native sequence metastatic colorectal cancer polypeptide (for O-linked glycosylation sites). The metastatic colorectal cancer amino acid sequence may optionally be altered through changes at the DNA level, particularly by mutating the DNA encoding the metastatic colorectal cancer polypeptide at preselected bases such that codons are generated that will translate into the desired amino acids.  
     [0172] Another means of increasing the number of carbohydrate moieties on the metastatic colorectal cancer polypeptide is by chemical or enzymatic coupling of glycosides to the polypeptide. Such methods are described in the art, e.g., in WO 87/05330, and in Aplin &amp; Wriston,  CRC Crit. Rev. Biochem.,  pp. 259-306 (1981).  
     [0173] Removal of carbohydrate moieties present on the metastatic colorectal cancer polypeptide may be accomplished chemically or enzymatically or by mutational substitution of codons encoding for amino acid residues that serve as targets for glycosylation. Chemical deglycosylation techniques are known in the art and described, for instance, by Hakimuddin, et al.,  Arch. Biochem. Biophys.,  259:52 (1987) and by Edge et al.,  Anal. Biochem.,  118:131 (1981). Enzymatic cleavage of carbohydrate moieties on polypeptides can be achieved by the use of a variety of endo-and exo-glycosidases as described by Thotakura et al.,  Meth. Enzymol.,  138:350 (1987).  
     [0174] Another type of covalent modification of metastatic colorectal cancer comprises linking the metastatic colorectal cancer polypeptide to one of a variety of nonproteinaceous polymers, e.g., polyethylene glycol, polypropylene glycol, or polyoxyalkylenes, in the manner set forth in U.S. Pat. Nos. 4,640,835; 4,496,689; 4,301,144; 4,670,417; 4,791,192 or 4,179,337.  
     [0175] Metastatic colorectal cancer polypeptides of the present invention may also be modified in a way to form chimeric molecules comprising a metastatic colorectal cancer polypeptide fused to another, heterologous polypeptide or amino acid sequence. In one embodiment, such a chimeric molecule comprises a fusion of a metastatic colorectal cancer polypeptide with a tag polypeptide which provides an epitope to which an anti-tag antibody can selectively bind. The epitope tag is generally placed at the amino-or carboxyl-terminus of the metastatic colorectal cancer polypeptide. The presence of such epitope-tagged forms of a metastatic colorectal cancer polypeptide can be detected using an antibody against the tag polypeptide. Also, provision of the epitope tag enables the metastatic colorectal cancer polypeptide to be readily purified by affinity purification using an anti-tag antibody or another type of affinity matrix that binds to the epitope tag. In an alternative embodiment, the chimeric molecule may comprise a fusion of a metastatic colorectal cancer polypeptide with an immunoglobulin or a particular region of an immunoglobulin. For a bivalent form of the chimeric molecule, such a fusion could be to the Fc region of an IgG molecule.  
     [0176] Various tag polypeptides and their respective antibodies are well known and examples include poly-histidine (poly-his) or poly-histidine-glycine (poly-his-gly) tags; HIS6 and metal chelation tags, the flu HA tag polypeptide and its antibody 12CA5 (Field et al.,  Mol. Cell. Biol.  8:2159-2165 (1988)); the c-myc tag and the 8F9, 3C7, 6E10, G4, B7 and 9E10 antibodies thereto (Evan et al.,  Molecular and Cellular Biology  5:3610-3616 (1985)); and the Herpes Simplex virus glycoprotein D (gD) tag and its antibody (Paborsky et al.,  Protein Engineering  3(6):547-553 (1990)). Other tag polypeptides include the Flag-peptide (Hopp et al.,  BioTechnology  6:1204-1210 (1988)); the KT3 epitope peptide (Martin et al.,  Science  255:192-194 (1992)); tubulin epitope peptide (Skinner et al.,  J. Biol. Chem.  266:15163-15166 (1991)); and the T7 gene 10 protein peptide tag (Lutz-Freyermuth et al.,  Proc. Natl. Acad. Sci. USA  87:6393-6397 (1990)).  
     [0177] Also included are other metastatic colorectal cancer proteins of the metastatic colorectal cancer family, and metastatic colorectal cancer proteins from other organisms, which are cloned and expressed as outlined below. Thus, probe or degenerate polymerase chain reaction (PCR) primer sequences may be used to find other related metastatic colorectal cancer proteins from primates or other organisms. As will be appreciated by those in the art, particularly useful probe and/or PCR primer sequences include unique areas of the metastatic colorectal cancer nucleic acid sequence. As is generally known in the art, preferred PCR primers are from about 15 to about 35 nucleotides in length, with from about 20 to about 30 being preferred, and may contain inosine as needed. PCR reaction conditions are well known in the art (e.g., Innis, PCR Protocols, supra).  
     [0178] Antibodies to Metastatic colorectal Cancer Proteins  
     [0179] In a preferred embodiment, when a metastatic colorectal cancer protein is to be used to generate antibodies, e.g., for immunotherapy or immunodiagnosis, the metastatic colorectal cancer protein should share at least one epitope or determinant with the full length protein. By “epitope” or “determinant” herein is typically meant a portion of a protein which will generate and/or bind an antibody or T-cell receptor in the context of MHC. Thus, in most instances, antibodies made to a smaller metastatic colorectal cancer protein will be able to bind to the full-length protein, particularly linear epitopes. In a preferred embodiment, the epitope is unique; that is, antibodies generated to a unique epitope show little or no cross-reactivity.  
     [0180] Methods of preparing polyclonal antibodies are well known (e.g., Coligan, supra; and Harlow &amp; Lane, supra). Polyclonal antibodies can be raised in a mammal, e.g., by one or more injections of an immunizing agent and, if desired, an adjuvant. Typically, the immunizing agent and/or adjuvant will be injected in the mammal by multiple subcutaneous or intraperitoneal injections. The immunizing agent may include a protein encoded by a nucleic acid of Tables 1-26 or fragment thereof or a fusion protein thereof. It may be useful to conjugate the immunizing agent to a protein known to be immunogenic in the mammal being immunized. Immunogenic proteins include, e.g., keyhole limpet hemocyanin, serum albumin, bovine thyroglobulin, and soybean trypsin inhibitor. Adjuvants include, e.g., Freund&#39;s complete adjuvant and MPL-TDM adjuvant (monophosphoryl Lipid A, synthetic trehalose dicorynomycolate). The immunization protocol may be selected by one skilled in the art.  
     [0181] The antibodies may, alternatively, be monoclonal antibodies. Monoclonal antibodies may be prepared using hybridoma methods, such as those described by Kohler &amp; Milstein,  Nature  256:495 (1975). In a hybridoma method, a mouse, hamster, or other appropriate host animal, is typically immunized with an immunizing agent to elicit lymphocytes that produce or are capable of producing antibodies that will specifically bind to the immunizing agent. Alternatively, the lymphocytes may be immunized in vitro. The immunizing agent will typically include a polypeptide encoded by a nucleic acid of Tables 1-26, or fragment thereof, or a fusion protein thereof Generally, either peripheral blood lymphocytes (“PBLs”) are used if cells of human origin are desired, or spleen cells or lymph node cells are used if non-human mammalian sources are desired. The lymphocytes are then fused with an immortalized cell line using a suitable fusing agent, such as polyethylene glycol, to form a hybridoma cell (Goding,  Monoclonal Antibodies: Principles and Practice,  pp. 59-103 (1986)). Immortalized cell lines are usually transformed mammalian cells, particularly myeloma cells of rodent, bovine and primate origin. Usually, rat or mouse myeloma cell lines are employed. The hybridoma cells may be cultured in a suitable culture medium that preferably contains one or more substances that inhibit the growth or survival of the unfused, immortalized cells. For example, if the parental cells lack the enzyme hypoxanthine guanine phosphoribosyl transferase (HGPRT or HPRT), the culture medium for the hybridomas typically will include hypoxanthine, aminopterin, and thymidine (“HAT medium”), which substances prevent the growth of HGPRT-deficient cells.  
     [0182] In one embodiment, the antibodies are bispecific antibodies. Bispecific antibodies are typically monoclonal, preferably human or humanized, antibodies that have binding specificities for at least two different antigens or that have binding specificities for two epitopes on the same antigen. In one embodiment, one of the binding specificities is for a protein encoded by a nucleic acid of Tables 1-26 or a fragment thereof, the other one is for any other antigen, and preferably for a cell-surface protein or receptor or receptor subunit, preferably one that is tumor specific. Alternatively, tetramer-type technology may create multivalent reagents.  
     [0183] In a preferred embodiment, the antibodies to metastatic colorectal cancer protein are capable of reducing or eliminating a biological function of a metastatic colorectal cancer protein, as is described below. That is, the addition of anti-metastatic colorectal cancer protein antibodies (either polyclonal or preferably monoclonal) to metastatic colorectal cancer tissue (or cells containing metastatic colorectal cancer) may reduce or eliminate the metastatic colorectal cancer. Generally, at least a 25% decrease in activity, growth, size or the like is preferred, with at least about 50% being particularly preferred and about a 95-100% decrease being especially preferred.  
     [0184] In a preferred embodiment the antibodies to the metastatic colorectal cancer proteins are humanized antibodies (e.g., Xenerex Biosciences, Mederex, Inc., Abgenix, Inc., Protein Design Labs, Inc.) Humanized forms of non-human (e.g., murine) antibodies are chimeric molecules of immunoglobulins, immunoglobulin chains or fragments thereof (such as Fv, Fab, Fab′, F(ab′)2 or other antigen-binding subsequences of antibodies) which contain minimal sequence derived from non-human immunoglobulin. Humanized antibodies include human immunoglobulins (recipient antibody) in which residues from a complementary determining region (CDR) of the recipient are replaced by residues from a CDR of a non-human species (donor antibody) such as mouse, rat or rabbit having the desired specificity, affinity and capacity. In some instances, Fv framework residues of the human immunoglobulin are replaced by corresponding non-human residues. Humanized antibodies may also comprise residues which are found neither in the recipient antibody nor in the imported CDR or framework sequences. In general, a humanized antibody will comprise substantially all of at least one, and typically two, variable domains, in which all or substantially all of the CDR regions correspond to those of a non-human immunoglobulin and all or substantially all of the framework (FR) regions are those of a human immunoglobulin consensus sequence. The humanized antibody optimally also will comprise at least a portion of an immunoglobulin constant region (Fc), typically that of a human immunoglobulin (Jones et al.,  Nature  321:522-525 (1986); Riechmann et al.,  Nature  332:323-329 (1988); and Presta,  Curr. Op. Struct. Biol.  2:593-596 (1992)). Humanization can be essentially performed following the method of Winter and co-workers (Jones et al.,  Nature  321:522-525 (1986); Riechmann et al.,  Nature  332:323-327 (1988); Verhoeyen et al.,  Science  239:1534-1536 (1988)), by substituting rodent CDRs or CDR sequences for the corresponding sequences of a human antibody. Accordingly, such humanized antibodies are chimeric antibodies (U.S. Pat. No. 4,816,567), wherein substantially less than an intact human variable domain has been substituted by the corresponding sequence from a non-human species.  
     [0185] Human-like antibodies can also be produced using various techniques known in the art, including phage display libraries (Hoogenboom &amp; Winter,  J. Mol. Biol.  227:381 (1991); Marks et al.,  J. Mol. Biol.  222:581 (1991)). The techniques of Cole et al. and Boerner et al. are also available for the preparation of human monoclonal antibodies (Cole et al.,  Monoclonal Antibodies and Cancer Therapy,  p. 77 (1985) and Boerner et al.,  J. Immunol.  147(1):86-95 (1991)). Similarly, human antibodies can be made by introducing of human immunoglobulin loci into transgenic animals, e.g., mice in which the endogenous immunoglobulin genes have been partially or completely inactivated. Upon challenge, human antibody production is observed, which closely resembles that seen in humans in virtually all respects, including gene rearrangement, assembly, and antibody repertoire. This approach is described, e.g., in U.S. Pat. Nos. 5,545,807; 5,545,806; 5,569,825; 5,625,126; 5,633,425; 5,661,016, and in the following scientific publications: Marks et al.,  Bio/Technology  10:779-783 (1992); Lonberg et al.,  Nature  368:856-859 (1994); Morrison,  Nature  368:812-13 (1994); Fishwild et al.,  Nature Biotechnology  14:845-51 (1996); Neuberger,  Nature Biotechnology  14:826 (1996); Lonberg &amp; Huszar,  Intern. Rev. Immunol.  13:65-93 (1995).  
     [0186] By immunotherapy is meant treatment of metastatic colorectal cancer with an antibody raised against a metastatic colorectal cancer proteins. As used herein, immunotherapy can be passive or active. Passive immunotherapy as defined herein is the passive transfer of antibody to a recipient (patient). Active immunization is the induction of antibody and/or T-cell responses in a recipient (patient). Induction of an immune response is the result of providing the recipient with an antigen to which antibodies are raised. The antigen may be provided by injecting a polypeptide against which antibodies are desired to be raised into a recipient, or contacting the recipient with a nucleic acid capable of expressing the antigen and under conditions for expression of the antigen, leading to an immune response.  
     [0187] In a preferred embodiment the metastatic colorectal cancer proteins against which antibodies are raised are secreted proteins as described above. Without being bound by theory, antibodies used for treatment, bind and prevent the secreted protein from binding to its receptor, thereby inactivating the secreted metastatic colorectal cancer protein.  
     [0188] In another preferred embodiment, the metastatic colorectal cancer protein to which antibodies are raised is a transmembrane protein. Without being bound by theory, antibodies used for this treatment typically bind the extracellular domain of the metastatic colorectal cancer protein and prevent it from binding to other proteins, such as circulating ligands or cell-associated molecules. The antibody may cause down-regulation of the transmembrane metastatic colorectal cancer protein. The antibody may be a competitive, non-competitive or uncompetitive inhibitor of protein binding to the extracellular domain of the metastatic colorectal cancer protein. The antibody may be an antagonist of the metastatic colorectal cancer protein or may prevent activation of the transmembrane metastatic colorectal cancer protein. In some embodiments, when the antibody prevents the binding of other molecules to the metastatic colorectal cancer protein, the antibody prevents growth of the cell. The antibody may also be used to target or sensitize the cell to cytotoxic agents, including, but not limited to TNF-α, TNF-β, IL-1, INF-γ and IL-2, or chemotherapeutic agents including 5FU, vinblastine, actinomycin D, cisplatin, methotrexate, and the like. In some instances the antibody belongs to a sub-type that activates serum complement when complexed with the transmembrane protein thereby mediating cytotoxicity or antigen-dependent cytotoxicity (ADCC). Thus, metastatic colorectal cancer is treated by administering to a patient antibodies directed against the transmembrane metastatic colorectal cancer protein. Antibody-labeling may activate a co-toxin, localize a toxin payload, or otherwise provide means to locally ablate cells.  
     [0189] In another preferred embodiment, the antibody is conjugated to an effector moiety. The effector moiety can be any number of molecules, including labeling moieties such as radioactive labels or fluorescent labels, or can be a therapeutic moiety. In one aspect the therapeutic moiety is a small molecule that modulates the activity of the metastatic colorectal cancer protein. In another aspect the therapeutic moiety modulates the activity of molecules associated with or in close proximity to the metastatic colorectal cancer protein. The therapeutic moiety may inhibit enzymatic activity such as protease or collagenase activity associated with metastatic colorectal cancer.  
     [0190] In a preferred embodiment, the therapeutic moiety can also be a cytotoxic agent. In this method, targeting the cytotoxic agent to metastatic colorectal cancer tissue or cells results in a reduction in the number of afflicted cells, thereby reducing symptoms associated with metastatic colorectal cancer. Cytotoxic agents are numerous and varied and include, but are not limited to, cytotoxic drugs or toxins or active fragments of such toxins. Suitable toxins and their corresponding fragments include diphtheria A chain, exotoxin A chain, ricin A chain, abrin A chain, curcin, crotin, phenomycin, enomycin and the like. Cytotoxic agents also include radiochemicals made by conjugating radioisotopes to antibodies raised against metastatic colorectal cancer proteins, or binding of a radionuclide to a chelating agent that has been covalently attached to the antibody. Targeting the therapeutic moiety to transmembrane metastatic colorectal cancer proteins not only serves to increase the local concentration of therapeutic moiety in the metastatic colorectal cancer afflicted area, but also serves to reduce deleterious side effects that may be associated with the therapeutic moiety.  
     [0191] In another preferred embodiment, the metastatic colorectal cancer protein against which the antibodies are raised is an intracellular protein. In this case, the antibody may be conjugated to a protein or other entity which facilitates entry into the cell. In one case, the antibody enters the cell by endocytosis. In another embodiment, a nucleic acid encoding the antibody is administered to the individual or cell. Moreover, wherein the metastatic colorectal cancer protein can be targeted within a cell, i.e., the nucleus, an antibody thereto contains a signal for that target localization, i.e., a nuclear localization signal.  
     [0192] The metastatic colorectal cancer antibodies of the invention specifically bind to metastatic colorectal cancer proteins. By “specifically bind” herein is meant that the antibodies bind to the protein with a K d  of at least about 0.1 mM, more usually at least about 1 μM, preferably at least about 0.1 μM or better, and most preferably, 0.01 μM or better. Selectivity of binding is also important.  
     [0193] Detection of Metastatic Colorectal Cancer Sequence for Diagnostic and Therapeutic Applications  
     [0194] In one aspect, the RNA expression levels of genes are determined for different cellular states in the metastatic colorectal cancer phenotype. Expression levels of genes in normal tissue (i.e., not undergoing metastatic colorectal cancer) and in metastatic colorectal cancer tissue (and in some cases, for varying severities of metastatic colorectal cancer that relate to prognosis, as outlined below) are evaluated to provide expression profiles. An expression profile of a particular cell state or point of development is essentially a “fingerprint” of the state. While two states may have any particular gene similarly expressed, the evaluation of a number of genes simultaneously allows the generation of a gene expression profile that is reflective of the state of the cell. By comparing expression profiles of cells in different states, information regarding which genes are important (including both up- and down-regulation of genes) in each of these states is obtained. Then, diagnosis may be performed or confirmed to determine whether a tissue sample has the gene expression profile of normal or cancerous tissue. This will provide for molecular diagnosis of related conditions.  
     [0195] “Differential expression,” or grammatical equivalents as used herein, refers to qualitative or quantitative differences in the temporal and/or cellular gene expression patterns within and among cells and tissue. Thus, a differentially expressed gene can qualitatively have its expression altered, including an activation or inactivation, in, e.g., normal versus metastatic colorectal cancer tissue. Genes may be turned on or turned off in a particular state, relative to another state thus permitting comparison of two or more states. A qualitatively regulated gene will exhibit an expression pattern within a state or cell type which is detectable by standard techniques. Some genes will be expressed in one state or cell type, but not in both. Alternatively, the difference in expression may be quantitative, e.g., in that expression is increased or decreased; i.e., gene expression is either upregulated, resulting in an increased amount of transcript, or downregulated, resulting in a decreased amount of transcript. The degree to which expression differs need only be large enough to quantify via standard characterization techniques as outlined below, such as by use of Affymetrix GeneChip™ expression arrays, Lockhart,  Nature Biotechnology  14:1675-1680 (1996), hereby expressly incorporated by reference. Other techniques include, but are not limited to, quantitative reverse transcriptase PCR, northern analysis and RNase protection. As outlined above, preferably the change in expression (i.e., upregulation or downregulation) is typically at least about 50%, more preferably at least about 100%, more preferably at least about 150%, more preferably at least about 200%, with from 300 to at least 1000% being especially preferred.  
     [0196] Evaluation may be at the gene transcript, or the protein level. The amount of gene expression may be monitored using nucleic acid probes to the DNA or RNA equivalent of the gene transcript, and the quantification of gene expression levels, or, alternatively, the final gene product itself (protein) can be monitored, e.g., with antibodies to the metastatic colorectal cancer protein and standard immunoassays (ELISAs, etc.) or other techniques, including mass spectroscopy assays, 2D gel electrophoresis assays, etc. Proteins corresponding to metastatic colorectal cancer genes, i.e., those identified as being important in a metastatic colorectal cancer phenotype, can be evaluated in a metastatic colorectal cancer diagnostic test.  
     [0197] In a preferred embodiment, gene expression monitoring is performed simultaneously on a number of genes.  
     [0198] The metastatic colorectal cancer nucleic acid probes may be attached to biochips as outlined herein for the detection and quantification of metastatic colorectal cancer sequences in a particular cell. The assays are further described below in the example. PCR techniques can be used to provide greater sensitivity. Multiple protein expression monitoring can be performed as well. Similarly, these assays may be performed on an individual basis as well.  
     [0199] In a preferred embodiment nucleic acids encoding the metastatic colorectal cancer protein are detected. Although DNA or RNA encoding the metastatic colorectal cancer protein may be detected, of particular interest are methods wherein an mRNA encoding a metastatic colorectal cancer protein is detected. Probes to detect mRNA can be a nucleotide/deoxynucleotide probe that is complementary to and hybridizes with the mRNA and includes, but is not limited to, oligonucleotides, cDNA or RNA. Probes also should contain a detectable label, as defined herein. In one method the mRNA is detected after immobilizing the nucleic acid to be examined on a solid support such as nylon membranes and hybridizing the probe with the sample. Following washing to remove the non-specifically bound probe, the label is detected. In another method detection of the mRNA is performed in situ. In this method permeabilized cells or tissue samples are contacted with a detectably labeled nucleic acid probe for sufficient time to allow the probe to hybridize with the target mRNA. Following washing to remove the non-specifically bound probe, the label is detected. For example a digoxygenin labeled riboprobe (RNA probe) that is complementary to the mRNA encoding a metastatic colorectal cancer protein is detected by binding the digoxygenin with an anti-digoxygenin secondary antibody and developed with nitro blue tetrazolium and 5-bromo-4-chloro-3-indoyl phosphate.  
     [0200] In a preferred embodiment, various proteins from the three classes of proteins as described herein (secreted, transmembrane or intracellular proteins) are used in diagnostic assays. The metastatic colorectal cancer proteins, antibodies, nucleic acids, modified proteins and cells containing metastatic colorectal cancer sequences are used in diagnostic assays. This can be performed on an individual gene or corresponding polypeptide level. In a preferred embodiment, the expression profiles are used, preferably in conjunction with high throughput screening techniques to allow monitoring for expression profile genes and/or corresponding polypeptides.  
     [0201] As described and defined herein, metastatic colorectal cancer proteins, including intracellular, transmembrane or secreted proteins, find use as markers of metastatic colorectal cancer. Detection of these proteins in putative metastatic colorectal cancer tissue allows for detection or diagnosis of metastatic colorectal cancer. In one embodiment, antibodies are used to detect metastatic colorectal cancer proteins. A preferred method separates proteins from a sample by electrophoresis on a gel (typically a denaturing and reducing protein gel, but may be another type of gel, including isoelectric focusing gels and the like). Following separation of proteins, the metastatic colorectal cancer protein is detected, e.g., by immunoblotting with antibodies raised against the metastatic colorectal cancer protein. Methods of immunoblotting are well known to those of ordinary skill in the art.  
     [0202] In another preferred method, antibodies to the metastatic colorectal cancer protein find use in in situ imaging techniques, e.g., in histology (e.g.,  Methods in Cell Biology: Antibodies in Cell Biology,  volume 37 (Asai, ed. 1993)). In this method cells are contacted with from one to many antibodies to the metastatic colorectal cancer protein(s). Following washing to remove non-specific antibody binding, the presence of the antibody or antibodies is detected. In one embodiment the antibody is detected by incubating with a secondary antibody that contains a detectable label, e.g., multicolor fluorescence or confocal imaging. In another method the primary antibody to the metastatic colorectal cancer protein(s) contains a detectable label, e.g., an enzyme marker that can act on a substrate. In another preferred embodiment each one of multiple primary antibodies contains a distinct and detectable label. This method finds particular use in simultaneous screening for a plurality of metastatic colorectal cancer proteins. Many other histological imaging techniques are also provided by the invention.  
     [0203] In a preferred embodiment the label is detected in a fluorometer which has the ability to detect and distinguish emissions of different wavelengths. In addition, a fluorescence activated cell sorter (FACS) can be used in the method.  
     [0204] In another preferred embodiment, antibodies find use in diagnosing metastatic colorectal cancer from blood, serum, plasma, stool, and other samples. Such samples, therefore, are useful as samples to be probed or tested for the presence of metastatic colorectal cancer proteins. Antibodies can be used to detect a metastatic colorectal cancer protein by previously described immunoassay techniques including ELISA, immunoblotting (western blotting), immunoprecipitation, BIACORE technology and the like. Conversely, the presence of antibodies may indicate an immune response against an endogenous metastatic colorectal cancer protein or vaccine.  
     [0205] In a preferred embodiment, in situ hybridization of labeled metastatic colorectal cancer nucleic acid probes to tissue arrays is done. For example, arrays of tissue samples, including metastatic colorectal cancer tissue and/or normal tissue, are made. In situ hybridization (see, e.g., Ausubel, supra) is then performed. When comparing the fingerprints between an individual and a standard, the skilled artisan can make a diagnosis, a prognosis, or a prediction based on the findings. It is further understood that the genes which indicate the diagnosis may differ from those which indicate the prognosis and molecular profiling of the condition of the cells may lead to distinctions between responsive or refractory conditions or may be predictive of outcomes.  
     [0206] In a preferred embodiment, the metastatic colorectal cancer proteins, antibodies, nucleic acids, modified proteins and cells containing metastatic colorectal cancer sequences are used in prognosis assays. As above, gene expression profiles can be generated that correlate to metastatic colorectal cancer, in terms of long term prognosis. Again, this may be done on either a protein or gene level, with the use of genes being preferred. As above, metastatic colorectal cancer probes may be attached to biochips for the detection and quantification of metastatic colorectal cancer sequences in a tissue or patient. The assays proceed as outlined above for diagnosis. PCR method may provide more sensitive and accurate quantification.  
     [0207] Assays for Therapeutic Compounds  
     [0208] In a preferred embodiment members of the three classes of proteins as described herein are used in drug screening assays. The metastatic colorectal cancer proteins, antibodies, nucleic acids, modified proteins and cells containing metastatic colorectal cancer sequences are used in drug screening assays or by evaluating the effect of drug candidates on a “gene expression profile” or expression profile of polypeptides. In a preferred embodiment, the expression profiles are used, preferably in conjunction with high throughput screening techniques to allow monitoring for expression profile genes after treatment with a candidate agent (e.g., Zlokarnik, et al.,  Science  279:84-8 (1998); Heid,  Genome Res  6:986-94, 1996).  
     [0209] In a preferred embodiment, the metastatic colorectal cancer proteins, antibodies, nucleic acids, modified proteins and cells containing the native or modified metastatic colorectal cancer proteins are used in screening assays. That is, the present invention provides novel methods for screening for compositions which modulate the metastatic colorectal cancer phenotype or an identified physiological function of a metastatic colorectal cancer protein. As above, this can be done on an individual gene level or by evaluating the effect of drug candidates on a “gene expression profile”. In a preferred embodiment, the expression profiles are used, preferably in conjunction with high throughput screening techniques to allow monitoring for expression profile genes after treatment with a candidate agent, see Zlokarnik, supra.  
     [0210] Having identified the differentially expressed genes herein, a variety of assays may be applied. In a preferred embodiment, assays may be run on an individual gene or protein level. That is, having identified a particular gene with altered regulation in metastatic colorectal cancer, test compounds can be screened for the ability to modulate gene expression or for binding to the metastatic colorectal cancer protein. “Modulation” thus includes an increase or a decrease in gene expression. The preferred amount of modulation will depend on the original change of the gene expression in normal versus tissue undergoing metastatic colorectal cancer, with changes of at least 10%, preferably 50%, more preferably 100-300%, and in some embodiments 300-1000% or greater. Thus, if a gene exhibits a 4-fold increase in metastatic colorectal cancer tissue compared to normal tissue, a decrease of about four-fold is often desired; similarly, a 10-fold decrease in metastatic colorectal cancer tissue compared to normal tissue often provides a target value of a 10-fold increase in expression to be induced by the test compound.  
     [0211] The amount of gene expression may be monitored using nucleic acid probes and the quantification of gene expression levels, or, alternatively, the gene product itself can be monitored, e.g., through the use of antibodies to the metastatic colorectal cancer protein and standard immunoassays. Proteomics and separation techniques may also allow quantification of expression.  
     [0212] In a preferred embodiment, gene or protein expression monitoring of a number of entities, i.e., an expression profile, is monitored simultaneously. Such profiles will typically involve a plurality of those entities described herein.  
     [0213] In this embodiment, the metastatic colorectal cancer nucleic acid probes are attached to biochips as outlined herein for the detection and quantification of metastatic colorectal cancer sequences in a particular cell. Alternatively, PCR may be used. Thus, a series, e.g., of microtiter plate, may be used with dispensed primers in desired wells. A PCR reaction can then be performed and analyzed for each well.  
     [0214] Expression monitoring can be performed to identify compounds that modify the expression of one or more metastatic colorectal cancer-associated sequences, e.g., a polynucleotide sequence set out in Tables 1-26. Generally, in a preferred embodiment, a test compound is added to the cells prior to analysis. Moreover, screens are also provided to identify agents that modulate metastatic colorectal cancer, modulate metastatic colorectal cancer proteins, bind to a metastatic colorectal cancer protein, or interfere with the binding of a metastatic colorectal cancer protein and an antibody, substrate, or other binding partner.  
     [0215] The term “test compound” or “drug candidate” or “modulator” or grammatical equivalents as used herein describes any molecule, e.g., protein, oligopeptide, small organic molecule, polysaccharide, polynucleotide, etc., to be tested for the capacity to directly or indirectly alter the metastatic colorectal cancer phenotype or the expression of a metastatic colorectal cancer sequence, e.g., a nucleic acid or protein sequence. In preferred embodiments, modulators alter expression profiles of nucleic acids or proteins provided herein. In one embodiment, the modulator suppresses a metastatic colorectal cancer phenotype, e.g., to a normal tissue fingerprint. In another embodiment, a modulator induces a metastatic colorectal cancer phenotype. Generally, a plurality of assay mixtures are run in parallel with different agent concentrations to obtain a differential response to the various concentrations. Typically, one of these concentrations serves as a negative control, i.e., at zero concentration or below the level of detection.  
     [0216] In one aspect, a modulator will neutralize the effect of a metastatic colorectal cancer protein. By “neutralize” is meant that activity of a protein and the consequent effect on the cell is inhibited or blocked.  
     [0217] In certain embodiments, combinatorial libraries of potential modulators will be screened for an ability to bind to a metastatic colorectal cancer polypeptide or to modulate activity. Conventionally, new chemical entities with useful properties are generated by identifying a chemical compound (called a “lead compound”) with some desirable property or activity, e.g., inhibiting activity, creating variants of the lead compound, and evaluating the property and activity of those variant compounds. Often, high throughput screening (HTS) methods are employed for such an analysis.  
     [0218] In one preferred embodiment, high throughput screening methods involve providing a library containing a large number of potential therapeutic compounds (candidate compounds). Such “combinatorial chemical libraries” are then screened in one or more assays to identify those library members (particular chemical species or subclasses) that display a desired characteristic activity. The compounds thus identified can serve as conventional “lead compounds” or can themselves be used as potential or actual therapeutics.  
     [0219] A combinatorial chemical library is a collection of diverse chemical compounds generated by either chemical synthesis or biological synthesis by combining a number of chemical “building blocks” such as reagents. For example, a linear combinatorial chemical library, such as a polypeptide (e.g., mutein) library, is formed by combining a set of chemical building blocks called amino acids in every possible way for a given compound length (i.e., the number of amino acids in a polypeptide compound). Millions of chemical compounds can be synthesized through such combinatorial mixing of chemical building blocks (Gallop et al.,  J. Med. Chem.  37(9):1233-1251 (1994)).  
     [0220] Preparation and screening of combinatorial chemical libraries is well known to those of skill in the art. Such combinatorial chemical libraries include, but are not limited to, peptide libraries (see, e.g., U.S. Pat. No. 5,010,175, Furka,  Pept. Prot. Res.  37:487-493 (1991), Houghton et al.,  Nature,  354:84-88 (1991)), peptoids (PCT Publication No WO 91/19735), encoded peptides (PCT Publication WO 93/20242), random bio-oligomers (PCT Publication WO 92/00091), benzodiazepines (U.S. Pat. No. 5,288,514), diversomers such as hydantoins, benzodiazepines and dipeptides (Hobbs et al.,  Proc. Nat. Acad. Sci. USA  90:6909-6913 (1993)), vinylogous polypeptides (Hagihara et al.,  J. Amer. Chem. Soc.  114:6568 (1992)), nonpeptidal peptidomimetics with a Beta-D-Glucose scaffolding (Hirschmann et al.,  J. Amer. Chem. Soc.  114:9217-9218 (1992)), analogous organic syntheses of small compound libraries (Chen et al.,  J. Amer. Chem. Soc.  116:2661 (1994)), oligocarbamates (Cho, et al.,  Science  261:1303 (1993)), and/or peptidyl phosphonates (Campbell et al.,  J. Org. Chem.  59:658 (1994)). See, generally, Gordon et al.,  J. Med. Chem.  37:1385 (1994), nucleic acid libraries (see, e.g., Strategene, Corp.), peptide nucleic acid libraries (see, e.g., U.S. Pat. No. 5,539,083), antibody libraries (see, e.g., Vaughn et al.,  Nature Biotechnology  14(3):309-314 (1996), and PCT/US96/10287), carbohydrate libraries (see, e.g., Liang et al.,  Science  274:1520-1522 (1996), and U.S. Pat. No. 5,593,853), and small organic molecule libraries (see, e.g., benzodiazepines, Baum, C&amp;EN, Jan 18, page 33 (1993); isoprenoids, U.S. Pat. No. 5,569,588; thiazolidinones and metathiazanones, U.S. Pat. No. 5,549,974; pyrrolidines, U.S. Pat. Nos. 5,525,735 and 5,519,134; morpholino compounds, U.S. Pat. No. 5,506,337; benzodiazepines, U.S. Pat. No. 5,288,514; and the like).  
     [0221] Devices for the preparation of combinatorial libraries are commercially available (see, e.g., 357 MPS, 390 MPS, Advanced Chem Tech, Louisville Ky., Symphony, Rainin, Woburn, Mass., 433A Applied Biosystems, Foster City, Calif., 9050 Plus, Millipore, Bedford, Mass.).  
     [0222] A number of well known robotic systems have also been developed for solution phase chemistries. These systems include automated workstations like the automated synthesis apparatus developed by Takeda Chemical Industries, LTD. (Osaka, Japan) and many robotic systems utilizing robotic arms (Zymate II, Zymark Corporation, Hopkinton, Mass.; Orca, Hewlett-Packard, Palo Alto, Calif.), which mimic the manual synthetic operations performed by a chemist. The above devices, with appropriate modification, are suitable for use with the present invention. In addition, numerous combinatorial libraries are themselves commercially available (see, e.g., ComGenex, Princeton, N.J., Asinex, Moscow, Ru, Tripos, Inc., St. Louis, Mo., ChemStar, Ltd, Moscow, RU, 3D Pharmaceuticals, Exton, Pa., Martek Biosciences, Columbia, Md., etc.).  
     [0223] The assays to identify modulators are amenable to high throughput screening. Preferred assays thus detect modulation of metastatic colorectal cancer gene transcription, polypeptide expression, and polypeptide activity.  
     [0224] High throughput assays for evaluating the presence, absence, quantification, or other properties of particular nucleic acids or protein products are well known to those of skill in the art. Similarly, binding assays and reporter gene assays are similarly well known. Thus, e.g., U.S. Pat. No. 5,559,410 discloses high throughput screening methods for proteins, U.S. Pat. No. 5,585,639 discloses high throughput screening methods for nucleic acid binding (i.e., in arrays), while U.S. Pat. Nos. 5,576,220 and 5,541,061 disclose high throughput methods of screening for ligand/antibody binding.  
     [0225] In addition, high throughput screening systems are commercially available (see, e.g., Zymark Corp., Hopkinton, Mass.; Air Technical Industries, Mentor, Ohio; Beckman Instruments, Inc. Fullerton, Calif.; Precision Systems, Inc., Natick, Mass., etc.). These systems typically automate procedures, including sample and reagent pipetting, liquid dispensing, timed incubations, and final readings of the microplate in detector(s) appropriate for the assay. These configurable systems provide high throughput and rapid start up as well as a high degree of flexibility and customization. The manufacturers of such systems provide detailed protocols for various high throughput systems. Thus, e.g., Zymark Corp. provides technical bulletins describing screening systems for detecting the modulation of gene transcription, ligand binding, and the like.  
     [0226] In one embodiment, modulators are proteins, often naturally occurring proteins or fragments of naturally occurring proteins. Thus, e.g., cellular extracts containing proteins, or random or directed digests of proteinaceous cellular extracts, may be used. In this way libraries of proteins may be made for screening in the methods of the invention. Particularly preferred in this embodiment are libraries of bacterial, fungal, viral, and mammalian proteins, with the latter being preferred, and human proteins being especially preferred. Particularly useful test compound will be directed to the class of proteins to which the target belongs, e.g., substrates for enzymes or ligands and receptors.  
     [0227] In a preferred embodiment, modulators are peptides of from about 5 to about 30 amino acids, with from about 5 to about 20 amino acids being preferred, and from about 7 to about 15 being particularly preferred. The peptides may be digests of naturally occurring proteins as is outlined above, random peptides, or “biased” random peptides. By “randomized” or grammatical equivalents herein is meant that the nucleic acid or peptide consists of essentially random sequences of nucleotides and amino acids, respectively. Since these random peptides (or nucleic acids, discussed below) are often chemically synthesized, they may incorporate any nucleotide or amino acid at any position. The synthetic process can be designed to generate randomized proteins or nucleic acids, to allow the formation of all or most of the possible combinations over the length of the sequence, thus forming a library of randomized candidate bioactive proteinaceous agents.  
     [0228] In one embodiment, the library is fully randomized, with no sequence preferences or constants at any position. In a preferred embodiment, the library is biased. That is, some positions within the sequence are either held constant, or are selected from a limited number of possibilities. In a preferred embodiment, the nucleotides or amino acid residues are randomized within a defined class, e.g., of hydrophobic amino acids, hydrophilic residues, sterically biased (either small or large) residues, towards the creation of nucleic acid binding domains, the creation of cysteines, for cross-linking, prolines for SH-3 domains, serines, threonines, tyrosines or histidines for phosphorylation sites, etc.  
     [0229] Modulators of metastatic colorectal cancer can also be nucleic acids, as defined above.  
     [0230] As described above generally for proteins, nucleic acid modulating agents may be naturally occurring nucleic acids, random nucleic acids, or “biased” random nucleic acids. Digests of procaryotic or eucaryotic genomes may be used as is outlined above for proteins.  
     [0231] In a preferred embodiment, the candidate compounds are organic chemical moieties, a wide variety of which are available in the literature.  
     [0232] After a candidate agent has been added and the cells allowed to incubate for some period of time, the sample containing a target sequence is analyzed. If required, the target sequence is prepared using known techniques. For example, the sample may be treated to lyse the cells, using known lysis buffers, electroporation, etc., with purification and/or amplification such as PCR performed as appropriate. For example, an in vitro transcription with labels covalently attached to the nucleotides is performed. Generally, the nucleic acids are labeled with biotin-FITC or PE, or with cy3 or cy5.  
     [0233] In a preferred embodiment, the target sequence is labeled with, e.g., a fluorescent, a chemiluminescent, a chemical, or a radioactive signal, to provide a means of detecting the target sequence&#39;s specific binding to a probe. The label also can be an enzyme, such as, alkaline phosphatase or horseradish peroxidase, which when provided with an appropriate substrate produces a product that can be detected. Alternatively, the label can be a labeled compound or small molecule, such as an enzyme inhibitor, that binds but is not catalyzed or altered by the enzyme. The label also can be a moiety or compound, such as, an epitope tag or biotin which specifically binds to streptavidin. For the example of biotin, the streptavidin is labeled as described above, thereby, providing a detectable signal for the bound target sequence. Unbound labeled streptavidin is typically removed prior to analysis.  
     [0234] Nucleic acid assays can be direct hybridization assays or can comprise “sandwich assays”, which include the use of multiple probes, as is generally outlined in U.S. Pat. Nos. 5,681,702, 5,597,909, 5,545,730, 5,594,117, 5,591,584, 5,571,670, 5,580,731, 5,571,670, 5,591,584, 5,624,802, 5,635,352, 5,594,118, 5,359,100, 5,124,246 and 5,681,697, all of which are hereby incorporated by reference. In this embodiment, in general, the target nucleic acid is prepared as outlined above, and then added to the biochip comprising a plurality of nucleic acid probes, under conditions that allow the formation of a hybridization complex.  
     [0235] A variety of hybridization conditions may be used in the present invention, including high, moderate and low stringency conditions as outlined above. The assays are generally run under stringency conditions which allow formation of the label probe hybridization complex only in the presence of target. Stringency can be controlled by altering a step parameter that is a thermodynamic variable, including, but not limited to, temperature, formamide concentration, salt concentration, chaotropic salt concentration, pH, organic solvent concentration, etc.  
     [0236] These parameters may also be used to control non-specific binding, as is generally outlined in U.S. Pat. No. 5,681,697. Thus it may be desirable to perform certain steps at higher stringency conditions to reduce non-specific binding.  
     [0237] The reactions outlined herein may be accomplished in a variety of ways. Components of the reaction may be added simultaneously, or sequentially, in different orders, with preferred embodiments outlined below. In addition, the reaction may include a variety of other reagents. These include salts, buffers, neutral proteins, e.g., albumin, detergents, etc. which may be used to facilitate optimal hybridization and detection, and/or reduce non-specific or background interactions. Reagents that otherwise improve the efficiency of the assay, such as protease inhibitors, nuclease inhibitors, anti-microbial agents, etc., may also be used as appropriate, depending on the sample preparation methods and purity of the target.  
     [0238] The assay data are analyzed to determine the expression levels, and changes in expression levels as between states, of individual genes, forming a gene expression profile.  
     [0239] Screens are performed to identify modulators of the metastatic colorectal cancer phenotype. In one embodiment, screening is performed to identify modulators that can induce or suppress a particular expression profile, thus preferably generating the associated phenotype. In another embodiment, e.g., for diagnostic applications, having identified differentially expressed genes important in a particular state, screens can be performed to identify modulators that alter expression of individual genes. In an another embodiment, screening is performed to identify modulators that alter a biological function of the expression product of a differentially expressed gene. Again, having identified the importance of a gene in a particular state, screens are performed to identify agents that bind and/or modulate the biological activity of the gene product, or evaluate genetic polymorphisms.  
     [0240] Genes can be screened for those that are induced in response to a candidate agent. After identifying a modulator based upon its ability to suppress a metastatic colorectal cancer expression pattern leading to a normal expression pattern, or to modulate a single metastatic colorectal cancer gene expression profile so as to mimic the expression of the gene from normal tissue, a screen as described above can be performed to identify genes that are specifically modulated in response to the agent. Comparing expression profiles between normal tissue and agent treated metastatic colorectal cancer tissue reveals genes that are not expressed in normal tissue or metastatic colorectal cancer tissue, but are expressed in agent treated tissue. These agent-specific sequences can be identified and used by methods described herein for metastatic colorectal cancer genes or proteins. In particular these sequences and the proteins they encode find use in marking or identifying agent treated cells. In addition, antibodies can be raised against the agent induced proteins and used to target novel therapeutics to the treated metastatic colorectal cancer tissue sample.  
     [0241] Thus, in one embodiment, a test compound is administered to a population of metastatic colorectal cancer cells, that have an associated metastatic colorectal cancer expression profile. By “administration” or “contacting” herein is meant that the candidate agent is added to the cells in such a manner as to allow the agent to act upon the cell, whether by uptake and intracellular action, or by action at the cell surface. In some embodiments, nucleic acid encoding a proteinaceous candidate agent (i.e., a peptide) may be put into a viral construct such as an adenoviral or retroviral construct, and added to the cell, such that expression of the peptide agent is accomplished, e.g., PCT US97/01019. Regulatable gene therapy systems can also be used.  
     [0242] Once the test compound has been administered to the cells, the cells can be washed if desired and are allowed to incubate under preferably physiological conditions for some period of time. The cells are then harvested and a new gene expression profile is generated, as outlined herein.  
     [0243] Thus, e.g., metastatic colorectal cancer tissue may be screened for agents that modulate, e.g., induce or suppress the metastatic colorectal cancer phenotype. A change in at least one gene, preferably many, of the expression profile indicates that the agent has an effect on metastatic colorectal cancer activity. By defining such a signature for the metastatic colorectal cancer phenotype, screens for new drugs that alter the phenotype can be devised. With this approach, the drug target need not be known and need not be represented in the original expression screening platform, nor does the level of transcript for the target protein need to change.  
     [0244] Measure of metastatic colorectal cancer polypeptide activity, or of metastatic colorectal cancer or the metastatic colorectal cancer phenotype can be performed using a variety of assays. For example, the effects of the test compounds upon the function of the metastatic polypeptides can be measured by examining parameters described above. A suitable physiological change that affects activity can be used to assess the influence of a test compound on the polypeptides of this invention. When the functional consequences are determined using intact cells or animals, one can also measure a variety of effects such as, in the case of metastatic colorectal cancer associated with tumors, tumor growth, tumor metastasis, neovascularization, hormone release, transcriptional changes to both known and uncharacterized genetic markers (e.g., northern blots), changes in cell metabolism such as cell growth or pH changes, and changes in intracellular second messengers such as cGMP. In the assays of the invention, mammalian metastatic colorectal cancer polypeptide is typically used, e.g., mouse, preferably human.  
     [0245] Assays to identify compounds with modulating activity can be performed in vitro. For example, a colorectal cancer polypeptide is first contacted with a potential modulator and incubated for a suitable amount of time, e.g., from 0.5 to 48 hours. In one embodiment, the metastatic colorectal cancer polypeptide levels are determined in vitro by measuring the level of protein or mRNA. The level of protein is measured using immunoassays such as western blotting, ELISA and the like with an antibody that selectively binds to the metastatic colorectal cancer polypeptide or a fragment thereof. For measurement of mRNA, amplification, e.g., using PCR, LCR, or hybridization assays, e.g., northern hybridization, RNAse protection, dot blotting, are preferred. The level of protein or mRNA is detected using directly or indirectly labeled detection agents, e.g., fluorescently or radioactively labeled nucleic acids, radioactively or enzymatically labeled antibodies, and the like, as described herein.  
     [0246] Alternatively, a reporter gene system can be devised using the metastatic colorectal cancer protein promoter operably linked to a reporter gene such as luciferase, green fluorescent protein, CAT, or β-gal. The reporter construct is typically transfected into a cell. After treatment with a potential modulator, the amount of reporter gene transcription, translation, or activity is measured according to standard techniques known to those of skill in the art.  
     [0247] In a preferred embodiment, as outlined above, screens may be done on individual genes and gene products (proteins). That is, having identified a particular differentially expressed gene as important in a particular state, screening of modulators of the expression of the gene or the gene product itself can be done. The gene products of differentially expressed genes are sometimes referred to herein as “metastatic colorectal cancer proteins.” The metastatic colorectal cancer protein may be a fragment, or alternatively, be the full length protein to a fragment shown herein.  
     [0248] In one embodiment, screening for modulators of expression of specific genes is performed. Typically, the expression of only one or a few genes are evaluated. In another embodiment, screens are designed to first find compounds that bind to differentially expressed proteins. These compounds are then evaluated for the ability to modulate differentially expressed activity. Moreover, once initial candidate compounds are identified, variants can be further screened to better evaluate structure activity relationships.  
     [0249] In a preferred embodiment, binding assays are done. In general, purified or isolated gene product is used; that is, the gene products of one or more differentially expressed nucleic acids are made. For example, antibodies are generated to the protein gene products, and standard immunoassays are run to determine the amount of protein present. Alternatively, cells comprising the metastatic colorectal cancer proteins can be used in the assays.  
     [0250] Thus, in a preferred embodiment, the methods comprise combining a metastatic colorectal cancer protein and a candidate compound, and determining the binding of the compound to the metastatic colorectal cancer protein. Preferred embodiments utilize the human metastatic colorectal cancer protein, although other mammalian proteins may also be used, e.g., for the development of animal models of human disease. In some embodiments, as outlined herein, variant or derivative metastatic colorectal cancer proteins may be used.  
     [0251] Generally, in a preferred embodiment of the methods herein, the metastatic colorectal cancer protein or the candidate agent is non-diffusably bound to an insoluble support having isolated sample receiving areas (e.g., a microtiter plate, an array, etc.). The insoluble supports may be made of any composition to which the compositions can be bound, is readily separated from soluble material, and is otherwise compatible with the overall method of screening. The surface of such supports may be solid or porous and of any convenient shape. Examples of suitable insoluble supports include microtiter plates, arrays, membranes and beads. These are typically made of glass, plastic (e.g., polystyrene), polysaccharides, nylon or nitrocellulose, teflon™, etc. Microtiter plates and arrays are especially convenient because a large number of assays can be carried out simultaneously, using small amounts of reagents and samples. The particular manner of binding of the composition is not crucial so long as it is compatible with the reagents and overall methods of the invention, maintains the activity of the composition and is nondiffusable. Preferred methods of binding include the use of antibodies (which do not sterically block either the ligand binding site or activation sequence when the protein is bound to the support), direct binding to “sticky” or ionic supports, chemical crosslinking, the synthesis of the protein or agent on the surface, etc. Following binding of the protein or agent, excess unbound material is removed by washing. The sample receiving areas may then be blocked through incubation with bovine serum albumin (BSA), casein or other innocuous protein or other moiety.  
     [0252] In a preferred embodiment, the metastatic colorectal cancer protein is bound to the support, and a test compound is added to the assay. Alternatively, the candidate agent is bound to the support and the metastatic colorectal cancer protein is added. Novel binding agents include specific antibodies, non-natural binding agents identified in screens of chemical libraries, peptide analogs, etc. Of particular interest are screening assays for agents that have a low toxicity for human cells. A wide variety of assays may be used for this purpose, including labeled in vitro protein-protein binding assays, electrophoretic mobility shift assays, immunoassays for protein binding, functional assays (phosphorylation assays, etc.) and the like.  
     [0253] The determination of the binding of the test modulating compound to the metastatic colorectal cancer protein may be done in a number of ways. In a preferred embodiment, the compound is labeled, and binding determined directly, e.g., by attaching all or a portion of the metastatic colorectal cancer protein to a solid support, adding a labeled candidate agent (e.g., a fluorescent label), washing off excess reagent, and determining whether the label is present on the solid support. Various blocking and washing steps may be utilized as appropriate.  
     [0254] In some embodiments, only one of the components is labeled, e.g., the proteins (or proteinaceous candidate compounds) can be labeled. Alternatively, more than one component can be labeled with different labels, e.g.,  125 I for the proteins and a fluorophor for the compound. Proximity reagents, e.g., quenching or energy transfer reagents are also useful.  
     [0255] In one embodiment, the binding of the test compound is determined by competitive binding assay. The competitor is a binding moiety known to bind to the target molecule (i.e., a metastatic colorectal cancer protein), such as an antibody, peptide, binding partner, ligand, etc. Under certain circumstances, there may be competitive binding between the compound and the binding moiety, with the binding moiety displacing the compound. In one embodiment, the test compound is labeled. Either the compound, or the competitor, or both, is added first to the protein for a time sufficient to allow binding, if present. Incubations may be performed at a temperature which facilitates optimal activity, typically between 4 and 40° C. Incubation periods are typically optimized, e.g., to facilitate rapid high throughput screening. Typically between 0.1 and 1 hour will be sufficient. Excess reagent is generally removed or washed away. The second component is then added, and the presence or absence of the labeled component is followed, to indicate binding.  
     [0256] In a preferred embodiment, the competitor is added first, followed by the test compound. Displacement of the competitor is an indication that the test compound is binding to the metastatic colorectal cancer protein and thus is capable of binding to, and potentially modulating, the activity of the metastatic colorectal cancer protein. In this embodiment, either component can be labeled. Thus, e.g., if the competitor is labeled, the presence of label in the wash solution indicates displacement by the agent. Alternatively, if the test compound is labeled, the presence of the label on the support indicates displacement.  
     [0257] In an alternative embodiment, the test compound is added first, with incubation and washing, followed by the competitor. The absence of binding by the competitor may indicate that the test compound is bound to the metastatic colorectal cancer protein with a higher affinity. Thus, if the test compound is labeled, the presence of the label on the support, coupled with a lack of competitor binding, may indicate that the test compound is capable of binding to the metastatic colorectal cancer protein.  
     [0258] In a preferred embodiment, the methods comprise differential screening to identity agents that are capable of modulating the activity of the metastatic colorectal cancer proteins. In this embodiment, the methods comprise combining a metastatic colorectal cancer protein and a competitor in a first sample. A second sample comprises a test compound, a metastatic colorectal cancer protein, and a competitor. The binding of the competitor is determined for both samples, and a change, or difference in binding between the two samples indicates the presence of an agent capable of binding to the metastatic colorectal cancer protein and potentially modulating its activity. That is, if the binding of the competitor is different in the second sample relative to the first sample, the agent is capable of binding to the metastatic colorectal cancer protein.  
     [0259] Alternatively, differential screening is used to identify drug candidates that bind to the native metastatic colorectal cancer protein, but cannot bind to modified metastatic colorectal cancer proteins. The structure of the metastatic colorectal cancer protein may be modeled, and used in rational drug design to synthesize agents that interact with that site. Drug candidates that affect the activity of a metastatic colorectal cancer protein are also identified by screening drugs for the ability to either enhance or reduce the activity of the protein.  
     [0260] Positive controls and negative controls may be used in the assays. Preferably control and test samples are performed in at least triplicate to obtain statistically significant results. Incubation of all samples is for a time sufficient for the binding of the agent to the protein. Following incubation, samples are washed free of non-specifically bound material and the amount of bound, generally labeled agent determined. For example, where a radiolabel is employed, the samples may be counted in a scintillation counter to determine the amount of bound compound.  
     [0261] A variety of other reagents may be included in the screening assays. These include reagents like salts, neutral proteins, e.g., albumin, detergents, etc. which may be used to facilitate optimal protein-protein binding and/or reduce non-specific or background interactions. Also reagents that otherwise improve the efficiency of the assay, such as protease inhibitors, nuclease inhibitors, anti-microbial agents, etc., may be used. The mixture of components may be added in an order that provides for the requisite binding.  
     [0262] In a preferred embodiment, the invention provides methods for screening for a compound capable of modulating the activity of a metastatic colorectal cancer protein. The methods comprise adding a test compound, as defined above, to a cell comprising metastatic colorectal cancer proteins. Preferred cell types include almost any cell. The cells contain a recombinant nucleic acid that encodes a metastatic colorectal cancer protein. In a preferred embodiment, a library of candidate agents are tested on a plurality of cells.  
     [0263] In one aspect, the assays are evaluated in the presence or absence or previous or subsequent exposure of physiological signals, e.g., hormones, antibodies, peptides, antigens, cytokines, growth factors, action potentials, pharmacological agents including chemotherapeutics, radiation, carcinogenics, or other cells (i.e. cell-cell contacts). In another example, the determinations are determined at different stages of the cell cycle process.  
     [0264] In this way, compounds that modulate metastatic colorectal cancer agents are identified. Compounds with pharmacological activity are able to enhance or interfere with the activity of the metastatic colorectal cancer protein. Once identified, similar structures are evaluated to identify critical structural feature of the compound.  
     [0265] In one embodiment, a method of inhibiting metastatic colorectal cancer cell division is provided. The method comprises administration of a metastatic colorectal cancer inhibitor. In another embodiment, a method of inhibiting metastatic colorectal cancer is provided. The method comprises administration of a metastatic colorectal cancer inhibitor. In a further embodiment, methods of treating cells or individuals with metastatic colorectal cancer are provided. The method comprises administration of a metastatic colorectal cancer inhibitor.  
     [0266] A variety of cell growth, proliferation, and metastasis assays are known to those of skill in the art, as described below.  
     [0267] Soft Agar Growth or Colony Formation in Suspension  
     [0268] Normal cells require a solid substrate to attach and grow. When the cells are transformed, they lose this phenotype and grow detached from the substrate. For example, transformed cells can grow in stirred suspension culture or suspended in semi-solid media, such as semi-solid or soft agar. The transformed cells, when transfected with tumor suppressor genes, regenerate normal phenotype and require a solid substrate to attach and grow. Soft agar growth or colony formation in suspension assays can be used to identify modulators of metastatic colorectal cancer sequences, which when expressed in host cells, inhibit abnormal cellular proliferation and transformation. A therapeutic compound would reduce or eliminate the host cells&#39; ability to grow in stirred suspension culture or suspended in semi-solid media, such as semi-solid or soft.  
     [0269] Techniques for soft agar growth or colony formation in suspension assays are described in Freshney,  Culture of Animal Cells a Manual of Basic Technique  (3 rd  ed., 1994), herein incorporated by reference. See also, the methods section of Garkavtsev et al. (1996), supra, herein incorporated by reference.  
     [0270] Contact Inhibition and Density Limitation of Growth  
     [0271] Normal cells typically grow in a flat and organized pattern in a petri dish until they touch other cells. When the cells touch one another, they are contact inhibited and stop growing. When cells are transformed, however, the cells are not contact inhibited and continue to grow to high densities in disorganized foci. Thus, the transformed cells grow to a higher saturation density than normal cells. This can be detected morphologically by the formation of a disoriented monolayer of cells or rounded cells in foci within the regular pattern of normal surrounding cells. Alternatively, labeling index with ( 3 H)-thymidine at saturation density can be used to measure density limitation of growth. See Freshney (1994), supra. The transformed cells, when transfected with tumor suppressor genes, regenerate a normal phenotype and become contact inhibited and would grow to a lower density.  
     [0272] In this assay, labeling index with ( 3 H)-thymidine at saturation density is a preferred method of measuring density limitation of growth. Transformed host cells are transfected with a metastatic colorectal cancer-associated sequence and are grown for 24 hours at saturation density in non-limiting medium conditions. The percentage of cells labeling with ( 3 H)-thymidine is determined autoradiographically. See, Freshney (1994), supra.  
     [0273] Growth Factor or Serum Dependence  
     [0274] Transformed cells have a lower serum dependence than their normal counterparts (see, e.g., Temin,  J. Natl. Cancer Insti.  37:167-175 (1966); Eagle et al.,  J. Exp. Med.  131:836-879 (1970)); Freshney, supra. This is in part due to release of various growth factors by the transformed cells. Growth factor or serum dependence of transformed host cells can be compared with that of control.  
     [0275] Tumor Specific Markers Levels  
     [0276] Tumor cells release an increased amount of certain factors (hereinafter “tumor specific markers”) than their normal counterparts. For example, plasminogen activator (PA) is released from human glioma at a higher level than from normal brain cells (see, e.g., Gullino,  Angiogenesis, tumor vascularization, and potential interference with tumor growth.  in  Biological Responses in Cancer,  pp. 178-184 (Mihich (ed.) 1985)). Similarly, Tumor angiogenesis factor (TAF) is released at a higher level in tumor cells than their normal counterparts. See, e.g., Folkman,  Angiogenesis and Cancer, Sem Cancer Biol.  (1992)).  
     [0277] Various techniques which measure the release of these factors are described in Freshney (1994), supra. Also, see, Unkless et al.,  J. Biol. Chem.  249:4295-4305 (1974); Strickland &amp; Beers,  J. Biol. Chem.  251:5694-5702 (1976); Whur et al.,  Br. J. Cancer  42:305-312 (1980); Gullino,  Angiogenesis, tumor vascularization, and potential interference with tumor growth.  in  Biological Responses in Cancer,  pp. 178-184 (Mihich (ed.) 1985); Freshney  Anticancer Res.  5:111-130 (1985).  
     [0278] Invasiveness Into Matrigel  
     [0279] The degree of invasiveness into Matrigel or some other extracellular matrix constituent can be used as an assay to identify compounds that modulate metastatic colorectal cancer-associated sequences. Tumor cells exhibit a good correlation between malignancy and invasiveness of cells into Matrigel or some other extracellular matrix constituent. In this assay, tumorigenic cells are typically used as host cells. Expression of a tumor suppressor gene in these host cells would decrease invasiveness of the host cells.  
     [0280] Techniques described in Freshney (1994), supra, can be used. Briefly, the level of invasion of host cells can be measured by using filters coated with Matrigel or some other extracellular matrix constituent. Penetration into the gel, or through to the distal side of the filter, is rated as invasiveness, and rated histologically by number of cells and distance moved, or by prelabeling the cells with  125 I and counting the radioactivity on the distal side of the filter or bottom of the dish. See, e.g., Freshney (1984), supra.  
     [0281] Tumor Growth in vivo  
     [0282] Effects of metastatic colorectal cancer-associated sequences on cell growth can be tested in transgenic or immune-suppressed mice. Knock-out transgenic mice can be made, in which the metastatic colorectal cancer gene is disrupted or in which a metastatic colorectal cancer gene is inserted. Knock-out transgenic mice can be made by insertion of a marker gene or other heterologous gene into the endogenous metastatic colorectal cancer gene site in the mouse genome via homologous recombination. Such mice can also be made by substituting the endogenous metastatic colorectal cancer gene with a mutated version of the metastatic colorectal cancer gene, or by mutating the endogenous metastatic colorectal cancer gene, e.g., by exposure to carcinogens.  
     [0283] A DNA construct is introduced into the nuclei of embryonic stem cells. Cells containing the newly engineered genetic lesion are injected into a host mouse embryo, which is re-implanted into a recipient female. Some of these embryos develop into chimeric mice that possess germ cells partially derived from the mutant cell line. Therefore, by breeding the chimeric mice it is possible to obtain a new line of mice containing the introduced genetic lesion (see, e.g., Capecchi et al.,  Science  244:1288 (1989)). Chimeric targeted mice can be derived according to Hogan et al.,  Manipulating the Mouse Embryo: A Laboratory Manual,  Cold Spring Harbor Laboratory (1988) and  Teratocarcinomas and Embryonic Stem Cells: A Practical Approach,  Robertson, ed., IRL Press, Washington, D.C., (1987).  
     [0284] Alternatively, various immune-suppressed or immune-deficient host animals can be used. For example, genetically athymic “nude” mouse (see, e.g., Giovanella et al.,  J. Natl. Cancer Inst.  52:921 (1974)), a SCID mouse, a thymectomized mouse, or an irradiated mouse (see, e.g., Bradley et al.,  Br. J. Cancer  38:263 (1978); Selby et al.,  Br. J. Cancer  41:52 (1980)) can be used as a host. Transplantable tumor cells (typically about 10 6  cells) injected into isogenic hosts will produce invasive tumors in a high proportions of cases, while normal cells of similar origin will not. In hosts which developed invasive tumors, cells expressing a metastatic colorectal cancer-associated sequences are injected subcutaneously. After a suitable length of time, preferably 4-8 weeks, tumor growth is measured (e.g., by volume or by its two largest dimensions) and compared to the control. Tumors that have statistically significant reduction (using, e.g., Student&#39;s T test) are said to have inhibited growth. Additionally, human tumor cells expressing the genes of the invention may be injected into immune compromised animals. Growth of these tumors, or xenografts, is compared to growth of similar human tumor cell that do not express the genes of the invention. These animals may also be used to binding assays and efficacy studies for therapeutic compounds that modulate metastatic colorectal cancer, such as antibodies or small molecules.  
     [0285] Polynucleotide Modulators of Metastatic Colorectal Cancer  
     [0286] Antisense Polynucleotides  
     [0287] In certain embodiments, the activity of a metastatic colorectal cancer-associated protein is downregulated, or entirely inhibited, by the use of antisense polynucleotide, i.e., a nucleic acid complementary to, and which can preferably hybridize specifically to, a coding mRNA nucleic acid sequence, e.g., a metastatic colorectal cancer protein mRNA, or a subsequence thereof. Binding of the antisense polynucleotide to the mRNA reduces the translation and/or stability of the mRNA.  
     [0288] In the context of this invention, antisense polynucleotides can comprise naturally-occurring nucleotides, or synthetic species formed from naturally-occurring subunits or their close homologs. Antisense polynucleotides may also have altered sugar moieties or inter-sugar linkages. Exemplary among these are the phosphorothioate and other sulfur containing species which are known for use in the art. Analogs are comprehended by this invention so long as they function effectively to hybridize with the metastatic colorectal cancer protein mRNA. See, e.g., Isis Pharmaceuticals, Carlsbad, Calif.; Sequitor, Inc., Natick, Mass.  
     [0289] Such antisense polynucleotides can readily be synthesized using recombinant means, or can be synthesized in vitro. Equipment for such synthesis is sold by several vendors, including Applied Biosystems. The preparation of other oligonucleotides such as phosphorothioates and alkylated derivatives is also well known to those of skill in the art.  
     [0290] Antisense molecules as used herein include antisense or sense oligonucleotides. Sense oligonucleotides can, e.g., be employed to block transcription by binding to the anti-sense strand. The antisense and sense oligonucleotide comprise a single-stranded nucleic acid sequence (either RNA or DNA) capable of binding to target mRNA (sense) or DNA (antisense) sequences for metastatic colorectal cancer molecules. A preferred antisense molecule is for a metastatic colorectal cancer sequence in Tables 1-26, or for a ligand or activator thereof. Antisense or sense oligonucleotides, according to the present invention, comprise a fragment generally at least about 14 nucleotides, preferably from about 14 to 30 nucleotides. The ability to derive an antisense or a sense oligonucleotide, based upon a cDNA sequence encoding a given protein is described in, e.g., Stein &amp; Cohen ( Cancer Res.  48:2659 (1988 and van der Krol et al. ( BioTechniques  6:958 (1988)).  
     [0291] Ribozymes  
     [0292] In addition to antisense polynucleotides, ribozymes can be used to target and inhibit transcription of metastatic colorectal cancer-associated nucleotide sequences. A ribozyme is an RNA molecule that catalytically cleaves other RNA molecules. Different kinds of ribozymes have been described, including group I ribozymes, hammerhead ribozymes, hairpin ribozymes, RNase P, and axhead ribozymes (see, e.g., Castanotto et al.,  Adv. in Pharmacology  25: 289-317 (1994) for a general review of the properties of different ribozymes).  
     [0293] The general features of hairpin ribozymes are described, e.g., in Hampel et al.,  Nucl. Acids Res.  18:299-304 (1990); European Patent Publication No. 0 360 257; U.S. Pat. No. 5,254,678. Methods of preparing are well known to those of skill in the art (see, e.g., WO 94/26877; Ojwang et al.,  Proc. Natl. Acad. Sci.  USA 90:6340-6344 (1993); Yamada et al.,  Human Gene Therapy  1:39-45 (1994); Leavitt et al.,  Proc. Natl. Acad. Sci. USA  92:699-703 (1995); Leavitt et al.,  Human Gene Therapy  5:1151-120 (1994); and Yamada et al.,  Virology  205: 121-126 (1994)).  
     [0294] Polynucleotide modulators of metastatic colorectal cancer may be introduced into a cell containing the target nucleotide sequence by formation of a conjugate with a ligand binding molecule, as described in WO 91/04753. Suitable ligand binding molecules include, but are not limited to, cell surface receptors, growth factors, other cytokines, or other ligands that bind to cell surface receptors. Preferably, conjugation of the ligand binding molecule does not substantially interfere with the ability of the ligand binding molecule to bind to its corresponding molecule or receptor, or block entry of the sense or antisense oligonucleotide or its conjugated version into the cell. Alternatively, a polynucleotide modulator of metastatic colorectal cancer may be introduced into a cell containing the target nucleic acid sequence, e.g., by formation of an polynucleotide-lipid complex, as described in WO 90/10448. It is understood that the use of antisense molecules or knock out and knock in models may also be used in screening assays as discussed above, in addition to methods of treatment.  
     [0295] Thus, in one embodiment, methods of modulating metastatic colorectal cancer in cells or organisms are provided. In one embodiment, the methods comprise administering to a cell an anti-metastatic colorectal cancer antibody that reduces or eliminates the biological activity of an endogenous metastatic colorectal cancer protein. Alternatively, the methods comprise administering to a cell or organism a recombinant nucleic acid encoding a metastatic colorectal cancer protein. This may be accomplished in any number of ways. In a preferred embodiment, e.g., when the metastatic colorectal cancer sequence is down-regulated in metastatic colorectal cancer, such state may be reversed by increasing the amount of metastatic colorectal cancer gene product in the cell. This can be accomplished, e.g., by overexpressing the endogenous metastatic colorectal cancer gene or administering a gene encoding the metastatic colorectal cancer sequence, using known gene-therapy techniques. In a preferred embodiment, the gene therapy techniques include the incorporation of the exogenous gene using enhanced homologous recombination (EHR), e.g., as described in PCT/US93/03868, hereby incorporated by reference in its entirety. Alternatively, e.g., when the metastatic colorectal cancer sequence is up-regulated in metastatic colorectal cancer, the activity of the endogenous metastatic colorectal cancer gene is decreased, e.g., by the administration of a metastatic colorectal cancer antisense nucleic acid.  
     [0296] In one embodiment, the metastatic colorectal cancer proteins of the present invention may be used to generate polyclonal and monoclonal antibodies to metastatic colorectal cancer proteins. Similarly, the metastatic colorectal cancer proteins can be coupled, using standard technology, to affinity chromatography columns. These columns may then be used to purify metastatic colorectal cancer antibodies useful for production, diagnostic, or therapeutic purposes. In a preferred embodiment, the antibodies are generated to epitopes unique to a metastatic colorectal cancer protein; that is, the antibodies show little or no cross-reactivity to other proteins. The metastatic colorectal cancer antibodies may be coupled to standard affinity chromatography columns and used to purify metastatic colorectal cancer proteins. The antibodies may also be used as blocking polypeptides, as outlined above, since they will specifically bind to the metastatic colorectal cancer protein.  
     [0297] Methods of Identifying Variant Metastatic Colorectal Cancer-Associated Sequences  
     [0298] Without being bound by theory, expression of various metastatic colorectal cancer sequences is correlated with metastatic colorectal cancer. Accordingly, disorders based on mutant or variant metastatic colorectal cancer genes may be determined. In one embodiment, the invention provides methods for identifying cells containing variant metastatic colorectal cancer genes, e.g., determining all or part of the sequence of at least one endogenous metastatic colorectal cancer genes in a cell. This may be accomplished using any number of sequencing techniques. In a preferred embodiment, the invention provides methods of identifying the metastatic colorectal cancer genotype of an individual, e.g., determining all or part of the sequence of at least one metastatic colorectal cancer gene of the individual. This is generally done in at least one tissue of the individual, and may include the evaluation of a number of tissues or different samples of the same tissue. The method may include comparing the sequence of the sequenced metastatic colorectal cancer gene to a known metastatic colorectal cancer gene, i.e., a wild-type gene.  
     [0299] The sequence of all or part of the metastatic colorectal cancer gene can then be compared to the sequence of a known metastatic colorectal cancer gene to determine if any differences exist. This can be done using any number of known homology programs, such as Bestfit, etc. In a preferred embodiment, the presence of a difference in the sequence between the metastatic colorectal cancer gene of the patient and the known metastatic colorectal cancer gene correlates with a disease state or a propensity for a disease state, as outlined herein.  
     [0300] In a preferred embodiment, the metastatic colorectal cancer genes are used as probes to determine the number of copies of the metastatic colorectal cancer gene in the genome.  
     [0301] In another preferred embodiment, the metastatic colorectal cancer genes are used as probes to determine the chromosomal localization of the metastatic colorectal cancer genes. Information such as chromosomal localization finds use in providing a diagnosis or prognosis in particular when chromosomal abnormalities such as translocations, and the like are identified in the metastatic colorectal cancer gene locus.  
     [0302] Administration of Pharmaceutical and Vaccine Compositions  
     [0303] In one embodiment, a therapeutically effective dose of a metastatic colorectal cancer protein or modulator thereof, is administered to a patient. By “therapeutically effective dose” herein is meant a dose that produces effects for which it is administered. The exact dose will depend on the purpose of the treatment, and will be ascertainable by one skilled in the art using known techniques (e.g., Ansel et al.,  Pharmaceutical Dosage Forms and Drug Delivery;  Lieberman,  Pharmaceutical Dosage Forms  (vols. 1-3, 1992), Dekker, ISBN 0824770846, 082476918X, 0824712692, 0824716981; Lloyd,  The Art, Science and Technology of Pharmaceutical Compounding  (1999); and Pickar,  Dosage Calculations  (1999)). As is known in the art, adjustments for metastatic colorectal cancer degradation, systemic versus localized delivery, and rate of new protease synthesis, as well as the age, body weight, general health, sex, diet, time of administration, drug interaction and the severity of the condition may be necessary, and will be ascertainable with routine experimentation by those skilled in the art.  
     [0304] A “patient” for the purposes of the present invention includes both humans and other animals, particularly mammals. Thus the methods are applicable to both human therapy and veterinary applications. In the preferred embodiment the patient is a mammal, preferably a primate, and in the most preferred embodiment the patient is human.  
     [0305] The administration of the metastatic colorectal cancer proteins and modulators thereof of the present invention can be done in a variety of ways as discussed above, including, but not limited to, orally, subcutaneously, intravenously, intranasally, transdermally, intraperitoneally, intramuscularly, intrapulmonary, vaginally, rectally, or intraocularly. In some instances, e.g., in the treatment of wounds and inflammation, the metastatic colorectal cancer proteins and modulators may be directly applied as a solution or spray.  
     [0306] The pharmaceutical compositions of the present invention comprise a metastatic colorectal cancer protein in a form suitable for administration to a patient. In the preferred embodiment, the pharmaceutical compositions are in a water soluble form, such as being present as pharmaceutically acceptable salts, which is meant to include both acid and base addition salts. “Pharmaceutically acceptable acid addition salt” refers to those salts that retain the biological effectiveness of the free bases and that are not biologically or otherwise undesirable, formed with inorganic acids such as hydrochloric acid, hydrobromic acid, sulfuric acid, nitric acid, phosphoric acid and the like, and organic acids such as acetic acid, propionic acid, glycolic acid, pyruvic acid, oxalic acid, maleic acid, malonic acid, succinic acid, fumaric acid, tartaric acid, citric acid, benzoic acid, cinnamic acid, mandelic acid, methanesulfonic acid, ethanesulfonic acid, p-toluenesulfonic acid, salicylic acid and the like. “Pharmaceutically acceptable base addition salts” include those derived from inorganic bases such as sodium, potassium, lithium, ammonium, calcium, magnesium, iron, zinc, copper, manganese, aluminum salts and the like. Particularly preferred are the ammonium, potassium, sodium, calcium, and magnesium salts. Salts derived from pharmaceutically acceptable organic non-toxic bases include salts of primary, secondary, and tertiary amines, substituted amines including naturally occurring substituted amines, cyclic amines and basic ion exchange resins, such as isopropylamine, trimethylamine, diethylamine, triethylamine, tripropylamine, and ethanolamine.  
     [0307] The pharmaceutical compositions may also include one or more of the following: carrier proteins such as serum albumin; buffers; fillers such as microcrystalline cellulose, lactose, corn and other starches; binding agents; sweeteners and other flavoring agents; coloring agents; and polyethylene glycol.  
     [0308] The pharmaceutical compositions can be administered in a variety of unit dosage forms depending upon the method of administration. For example, unit dosage forms suitable for oral administration include, but are not limited to, powder, tablets, pills, capsules and lozenges. It is recognized that metastatic colorectal cancer protein modulators (e.g., antibodies, antisense constructs, ribozymes, small organic molecules, etc.) when administered orally, should be protected from digestion. It is also recognized that, after delivery to other sites in the body (e.g., circulatory system, lymphatic system, or the tumor site) the metastatic colorectal cancer modulators of the invention may need to be protected from excretion, hydrolisis, proteolytic digestion or modification, or detoxification by the liver. In all these cases, protection is typically accomplished either by complexing the molecule(s) with a composition to render it resistant to acidic and enzymatic hydrolysis, or by packaging the molecule(s) in an appropriately resistant carrier, such as a liposome or a protection barrier or by modifying the molecular size, weight, and/or charge of the modulator. Means of protecting agents from digestion degradation, and excretion are well known in the art.  
     [0309] The compositions for administration will commonly comprise a metastatic colorectal cancer protein modulator dissolved in a pharmaceutically acceptable carrier, preferably an aqueous carrier. A variety of aqueous carriers can be used, e.g., buffered saline and the like. These solutions are sterile and generally free of undesirable matter. These compositions may be sterilized by conventional, well known sterilization techniques. The compositions may contain pharmaceutically acceptable auxiliary substances as required to approximate physiological conditions such as pH adjusting and buffering agents, toxicity adjusting agents and the like, e.g., sodium acetate, sodium chloride, potassium chloride, calcium chloride, sodium lactate and the like. The concentration of active agent in these formulations can vary widely, and will be selected primarily based on fluid volumes, viscosities, body weight and the like in accordance with the particular mode of administration selected and the patient&#39;s needs (e.g.,  Remington&#39;s Pharmaceutical Science  (15th ed., 1980) and Goodman &amp; Gillman,  The Pharmacologial Basis of Therapeutics  (Hardman et al., eds., 1996)).  
     [0310] Thus, a typical pharmaceutical composition for intravenous administration would be about 0.1 to 10 mg per patient per day. Dosages from 0.1 up to about 100 mg per patient per day may be used, particularly when the drug is administered to a secluded site and not into the blood stream, such as into a body cavity or into a lumen of an organ. Substantially higher dosages are possible in topical administration. Actual methods for preparing parenterally administrable compositions will be known or apparent to those skilled in the art, e.g.,  Remington &#39;s Pharmaceutical Science  and Goodman and Gilhman,  The Pharmacologial Basis of Therapeutics, supra.    
     [0311] The compositions containing modulators of metastatic colorectal cancer proteins can be administered for therapeutic or prophylactic treatments. In therapeutic applications, compositions are administered to a patient suffering from a disease (e.g., a cancer) in an amount sufficient to cure or at least partially arrest the disease and its complications. An amount adequate to accomplish this is defined as a “therapeutically effective dose.” Amounts effective for this use will depend upon the severity of the disease and the general state of the patient&#39;s health. Single or multiple administrations of the compositions may be administered depending on the dosage and frequency as required and tolerated by the patient. In any event, the composition should provide a sufficient quantity of the agents of this invention to effectively treat the patient. An amount of modulator that is capable of preventing or slowing the development of cancer in a mammal is referred to as a “prophylactically effective dose.” The particular dose required for a prophylactic treatment will depend upon the medical condition and history of the mammal, the particular cancer being prevented, as well as other factors such as age, weight, gender, administration route, efficiency, etc. Such prophylactic treatments may be used, e.g., in a mammal who has previously had cancer to prevent a recurrence of the cancer, or in a mammal who is suspected of having a significant likelihood of developing cancer.  
     [0312] It will be appreciated that the present metastatic colorectal cancer protein-modulating compounds can be administered alone or in combination with additional metastatic colorectal cancer modulating compounds or with other therapeutic agent, e.g., other anti-cancer agents or treatments.  
     [0313] In numerous embodiments, one or more nucleic acids, e.g., polynucleotides comprising nucleic acid sequences set forth in Tables 1-26, such as antisense polynucleotides or ribozymes, will be introduced into cells, in vitro or in vivo. The present invention provides methods, reagents, vectors, and cells useful for expression of metastatic colorectal cancer-associated polypeptides and nucleic acids using in vitro (cell-free), ex vivo or in vivo (cell or organism-based) recombinant expression systems.  
     [0314] The particular procedure used to introduce the nucleic acids into a host cell for expression of a protein or nucleic acid is application specific. Many procedures for introducing foreign nucleotide sequences into host cells may be used. These include the use of calcium phosphate transfection, spheroplasts, electroporation, liposomes, microinjection, plasma vectors, viral vectors and any of the other well known methods for introducing cloned genomic DNA, cDNA, synthetic DNA or other foreign genetic material into a host cell (see, e.g., Berger &amp; Kimmel,  Guide to Molecular Cloning Techniques, Methods in Enzymology  volume 152 (Berger), Ausubel et al., eds.,  Current Protocols  (supplemented through 1999), and Sambrook et al.,  Molecular Cloning—A Laboratory Manual  (2nd ed., Vol. 1-3, 1989.  
     [0315] In a preferred embodiment, metastatic colorectal cancer proteins and modulators are administered as therapeutic agents, and can be formulated as outlined above. Similarly, metastatic colorectal cancer genes (including both the full-length sequence, partial sequences, or regulatory sequences of the metastatic colorectal cancer coding regions) can be administered in a gene therapy application. These metastatic colorectal cancer genes can include antisense applications, either as gene therapy (i.e., for incorporation into the genome) or as antisense compositions, as will be appreciated by those in the art.  
     [0316] Metastatic colorectal cancer polypeptides and polynucleotides can also be administered as vaccine compositions to stimulate HTL, CTL and antibody responses. Such vaccine compositions can include, e.g., lipidated peptides (see, e.g., Vitiello, et al.,  J. Clin. Invest.  95:341 (1995)), peptide compositions encapsulated in poly(DL-lactide-co-glycolide) (“PLG”) microspheres (see, e.g., Eldridge, et al.,  Molec. Immunol.  28:287-294, (1991); Alonso et al.,  Vaccine  12:299-306 (1994); Jones et al.,  Vaccine  13:675-681 (1995)), peptide compositions contained in immune stimulating complexes (ISCOMS) (see, e.g., Takahashi et al.,  Nature  344:873-875 (1990); Hu et al.,  Clin Exp Immunol.  113:235-243 (1998)), multiple antigen peptide systems (MAPs) (see, e.g., Tam,  Proc. Natl. Acad. Sci. U.S.A.  85:5409-5413 (1988); Tam,  J. Immunol. Methods  196:17-32 (1996)), peptides formulated as multivalent peptides; peptides for use in ballistic delivery systems, typically crystallized peptides, viral delivery vectors (Perkus, et al., In:  Concepts in vaccine development  (Kaufmann, ed., p. 379, 1996); Chakrabarti, et al.,  Nature  320:535 (1986); Hu et al.,  Nature  320:537 (1986); Kieny, et al.,  AIDS Bio/Technology  4:790 (1986); Top et al.,  J. Infect. Dis.  124:148 (1971); Chanda et al.,  Virology  175:535 (1990)), particles of viral or synthetic origin (see, e.g., Kofler et al.,  J. Immunol. Methods.  192:25 (1996); Eldridge et al.,  Sem. Hematol.  30:16 (1993); Falo et al.,  Nature Med.  7:649 (1995)), adjuvants (Warren et al.,  Annu. Rev. Immunol.  4:369 (1986); Gupta et al.,  Vaccine  11:293 (1993)), liposomes (Reddy et al.,  J. Immunol.  148:1585 (1992); Rock,  Immunol. Today  17:131 (1996)), or, naked or particle absorbed cDNA (Ulmer, et al.,  Science  259:1745 (1993); Robinson et al.,  Vaccine  11:957 (1993); Shiver et al., In:  Concepts in vaccine development  (Kaufmann, ed., p. 423, 1996); Cease &amp; Berzofsky,  Annu. Rev. Immunol.  12:923 (1994) and Eldridge et al.,  Sem. Hematol.  30:16 (1993)). Toxin-targeted delivery technologies, also known as receptor mediated targeting, such as those of Avant Immunotherapeutics, Inc. (Needham, Mass.) may also be used.  
     [0317] Vaccine compositions often include adjuvants. Many adjuvants contain a substance designed to protect the antigen from rapid catabolism, such as aluminum hydroxide or mineral oil, and a stimulator of immune responses, such as lipid A,  Bortadella pertussis  or  Mycobacterium tuberculosis  derived proteins. Certain adjuvants are commercially available as, e.g., Freund&#39;s Incomplete Adjuvant and Complete Adjuvant (Difco Laboratories, Detroit, Mich.); Merck Adjuvant 65 (Merck and Company, Inc., Rahway, N.J.); AS-2 (SmithKline Beecham, Philadelphia, Pa.); aluminum salts such as aluminum hydroxide gel (alum) or aluminum phosphate; salts of calcium, iron or zinc; an insoluble suspension of acylated tyrosine; acylated sugars; cationically or anionically derivatized polysaccharides; polyphosphazenes; biodegradable microspheres; monophosphoryl lipid A and quil A. Cytokines, such as GM-CSF, interleukin-2, -7, -12, and other like growth factors, may also be used as adjuvants.  
     [0318] Vaccines can be administered as nucleic acid compositions wherein DNA or RNA encoding one or more of the polypeptides, or a fragment thereof, is administered to a patient. This approach is described, for instance, in Wolff et. al.,  Science  247:1465 (1990) as well as U.S. Pat. Nos. 5,580,859; 5,589,466; 5,804,566; 5,739,118; 5,736,524; 5,679,647; WO 98/04720; and in more detail below. Examples of DNA-based delivery technologies include “naked DNA”, facilitated (bupivicaine, polymers, peptide-mediated) delivery, cationic lipid complexes, and particle-mediated (“gene gun”) or pressure-mediated delivery (see, e.g., U.S. Pat. No. 5,922,687).  
     [0319] For therapeutic or prophylactic immunization purposes, the peptides of the invention can be expressed by viral or bacterial vectors. Examples of expression vectors include attenuated viral hosts, such as vaccinia or fowlpox. This approach involves the use of vaccinia virus, e.g., as a vector to express nucleotide sequences that encode metastatic colorectal cancer polypeptides or polypeptide fragments. Upon introduction into a host, the recombinant vaccinia virus expresses the immunogenic peptide, and thereby elicits an immune response. Vaccinia vectors and methods useful in immunization protocols are described in, e.g., U.S. Pat. No. 4,722,848. Another vector is BCG (Bacille Calmette Guerin). BCG vectors are described in Stover et al.,  Nature  351:456-460 (1991). A wide variety of other vectors useful for therapeutic administration or immunization e.g., adeno and adeno-associated virus vectors, retroviral vectors,  Salmonella typhi  vectors, detoxified anthrax toxin vectors, and the like, will be apparent to those skilled in the art from the description herein (see, e.g., Shata et al.,  Mol Med Today  6:66-71 (2000); Shedlock et al.,  J. Leukoc Biol  68:793-806 (2000); Hipp et al., In Vivo 14:571-85 (2000)).  
     [0320] Methods for the use of genes as DNA vaccines are well known, and include placing a metastatic colorectal cancer gene or portion of a metastatic colorectal cancer gene under the control of a regulatable promoter or a tissue-specific promoter for expression in a metastatic colorectal cancer patient. The metastatic colorectal cancer gene used for DNA vaccines can encode full-length metastatic colorectal cancer proteins, but more preferably encodes portions of the metastatic colorectal cancer proteins including peptides derived from the metastatic colorectal cancer protein. In one embodiment, a patient is immunized with a DNA vaccine comprising a plurality of nucleotide sequences derived from a metastatic colorectal cancer gene. For example, metastatic colorectal cancer-associated genes or sequence encoding subfragments of a metastatic colorectal cancer protein are introduced into expression vectors and tested for their immunogenicity in the context of Class I MHC and an ability to generate cytotoxic T cell responses. This procedure provides for production of cytotoxic T cell responses against cells which present antigen, including intracellular epitopes.  
     [0321] In a preferred embodiment, the DNA vaccines include a gene encoding an adjuvant molecule with the DNA vaccine. Such adjuvant molecules include cytokines that increase the immunogenic response to the metastatic colorectal cancer polypeptide encoded by the DNA vaccine. Additional or alternative adjuvants are available.  
     [0322] In another preferred embodiment metastatic colorectal cancer genes find use in generating animal models of metastatic colorectal cancer. When the metastatic colorectal cancer gene identified is repressed or diminished in metastatic tissue, gene therapy technology, e.g., wherein antisense RNA directed to the metastatic colorectal cancer gene will also diminish or repress expression of the gene. Animal models of metastatic colorectal cancer find use in screening for modulators of a metastatic colorectal cancer-associated sequence or modulators of metastatic colorectal cancer. Similarly, transgenic animal technology including gene knockout technology, e.g., as a result of homologous recombination with an appropriate gene targeting vector, will result in the absence or increased expression of the metastatic colorectal cancer protein. When desired, tissue-specific expression or knockout of the metastatic colorectal cancer protein may be necessary.  
     [0323] It is also possible that the metastatic colorectal cancer protein is overexpressed in metastatic colorectal cancer. As such, transgenic animals can be generated that overexpress the metastatic colorectal cancer protein. Depending on the desired expression level, promoters of various strengths can be employed to express the transgene. Also, the number of copies of the integrated transgene can be determined and compared for a determination of the expression level of the transgene. Animals generated by such methods find use as animal models of metastatic colorectal cancer and are additionally useful in screening for modulators to treat metastatic colorectal cancer.  
     [0324] Kits for Use in Diagnostic and/or Prognostic Applications  
     [0325] For use in diagnostic, research, and therapeutic applications suggested above, kits are also provided by the invention. In the diagnostic and research applications such kits may include any or all of the following: assay reagents, buffers, metastatic colorectal cancer-specific nucleic acids or antibodies, hybridization probes and/or primers, antisense polynucleotides, ribozymes, dominant negative metastatic colorectal cancer polypeptides or polynucleotides, small molecules inhibitors of metastatic colorectal cancer-associated sequences etc. A therapeutic product may include sterile saline or another pharmaceutically acceptable emulsion and suspension base.  
     [0326] In addition, the kits may include instructional materials containing directions (i.e., protocols) for the practice of the methods of this invention. While the instructional materials typically comprise written or printed materials they are not limited to such. Any medium capable of storing such instructions and communicating them to an end user is contemplated by this invention. Such media include, but are not limited to electronic storage media (e.g., magnetic discs, tapes, cartridges, chips), optical media (e.g., CD ROM), and the like. Such media may include addresses to internet sites that provide such instructional materials.  
     [0327] The present invention also provides for kits for screening for modulators of metastatic colorectal cancer-associated sequences. Such kits can be prepared from readily available materials and reagents. For example, such kits can comprise one or more of the following materials: a metastatic colorectal cancer-associated polypeptide or polynucleotide, reaction tubes, and instructions for testing metastatic colorectal cancer-associated activity. Optionally, the kit contains biologically active metastatic colorectal cancer protein. A wide variety of kits and components can be prepared according to the present invention, depending upon the intended user of the kit and the particular needs of the user. Diagnosis would typically involve evaluation of a plurality of genes or products. The genes will be selected based on correlations with important parameters in disease which may be identified in historical or outcome data.  
                           TABLE 1                                      Pkey:   Unique Eas probeset identifier nnmber           ExAccn:   Exemplar Aceession number, Genbank accession nnmber           UnigeneID:   Unigene number           Unigene Title:   Unigene gene title                                                     Ratio           Pkey   ExAccn   UnigeneID   Unigene Title   Mets/BS   Top 3 expressing cell lines                                             103989   AA314779   Hs.105484   ESTs; Weakly similar to LITHOSTATHINE 1   15.77   EB_cells, HT29_cells, HMEC       101169   L15533   Hs.423   pancreatitis-associated protein   11.98   HMEC (total RNA), Fibroblasts 2,                           Fibroblasts 2       101880   M97925   Hs.72887   defensin; alpha 5; Paneth cell-specific   9.24   Fibroblasts 2, MB231_sells, MB-MDA-453       129462   D84239   Hs.111732   IgG Fc binding protein   8.57   EB_cells, OVCAR_cells, HS578T_cells       131676   C20785   Hs.30514   ESTs   7.43   HMEC (total RNA), HMEC, Fibroblasts 2       131861   D11925   Hs.184245   KIAA0929 protein Msx2 interacting nuclea   7.15   HMEC, HMEC (total RNA), Fibroblasts 2       118823   N79237   Hs.50813   ESTs; Weakly similar to long chain fatty   6.72   HMEC, HMEC (total RNA), Lu_AD_H23       101107   L08010   Hs.4158   regenerating islet-derived 1 beta (pancr   6.33   BT474_cells, Fibroblasts 2, MB231_cells       103466   Y00339   Hs.155097   carbonic anhydrase II   6.18   OVCAR_cells, MCF7, 293T_cells       102306   U33317   Hs.711   defensin; alpha 6; Paneth cell-specific   5.67   Fibroblasts 2, HMEC, HT29_cells       126419   AA451775   Hs.129064     H sapiens  chromosome 19; cosmid F22162   5.14   HS578T_cells, HMEC (total RNA), HMEC       101198   L21998   Hs.315   mucin 2; intestinal/tracheal   5.1   EB_cells, HT29_cells, MB231_cells       107652   AA010195   Hs.52642   ESTs; Weakly similar to !!!! ALU CLASS F   4.94   HMEC (total RNA), HMEC, EB_cells       128145   AI498467   Hs.166669   ESTs; Weakly similar to sodium bicarbona   4.77   HS578T_cells, HMEC, Lu_SQ_H520       110660   H82117   Hs.28043   ESTs   4.54   HMEC, HS578T_cells, BT474_cells       111669   R19305   Hs.110347     H sapiens  mRNA for alpha integrin bindin   4.52   HMEC, HS578T_cells, Caco2       124867   R68971   Hs.188500   ESTs   4.5   HMEC, HMEC (total RNA), HS578T_cells       127352   AA416577   Hs.189105   ESTs   4.41   HMEC, HMEC (total RNA),                           MB-MDA-435s       130736   T99385   Hs.18646   EST   4.29   HMEC, EB_cells, HMEC (total RNA)       128592   AA470056   Hs.113994   ESTs; Weakly similar to alternatively sp   4.18   HMEC (total RNA), HMEC, Fibroblasts 2       108092   AA045961   Hs.169355   ESTs; Weakly similar to   4.04   HMEC (total RNA), HMEC, Fibroblasts 2                   TRANSCRIPTION RE       133373   S72487   Hs.73946   endothellal cell growth factor 1 (platel   4.03   EB_cells, HMEC, HMEC (total RNA)       100572   HG2271       Profilaggrin   4.03   HMEC (total RNA), HMEC, Fibroblasts 2       115775   AA424030   Hs.46627   ESTs   4.02   HMEC, HMEC (total RNA), EB_cells       120811   AA346854   Hs.52788   fragile X mental retardation; autosomal   4.01   HMEC (total RNA), HMEC, Fibroblasts 2       111919   R39926   Hs.21031   ESTs   3.98   EB_cells, HMEC (total RNA), HMEC       117009   H85422   Hs.108556   ESTs   3.97   HMEC (total RNA), HMEC, Fibroblasts 2       101124   L10343   Hs.112341   protease inhibitor 3; skin-derived (SKAL   3.89   PC3_cells, RPWE_2, Caco2       106151   AA424958   Hs.33735   ESTs   3.88   EBsells, HMEC, HMEC (total RNA)       134733   U03644   Hs.89421   CBF1 interacting corepressor   3.88   EB_cells, HMEC, HMEC (total RNA)       131739   AA449749   Hs.31386   ESTs; Highly similar to secreted apoptos   3.87   HS578T_cells, MB-MDA-435s,                           HT29_cells       116311   AA490469   Hs.48752   ESTs   3.84   HS578T_cells, HMEC, LNCaP_cells       134174   U05259   Hs.79630   CD79A antigen (immunoglobulin-associated   3.83   DU145_cells, Lu_AD_H23, MB231_cells       106753   AA476944   Hs.7331   ESTs   3.82   LNCaP_sells, Lu_SC_H345, DU145_cells       104842   AA039854   Hs.8065     H sapiens  mRNA full length insert cDNA c   3.78   HS578T_cells, A549_cells, CALU6_cells       129161   N27334   Hs.181780   ESTs   3.75   HMEC (total RNA), HMEC, BT474_cells       105675   AA284767   Hs.252808   ESTs; Highly similar to pulmonary surfac   3.75   293T_cells, PRSC_con, HT29_cells       100547   HG2149       Mucin (Gb:M57417)   3.75   HMEC (total RNA), HMEC, Fibroblasts 2       116887   H65841   Hs.186550   ESTs   3.73   HS578T_cells, 293T_cells, HMEC       113222   T59670   Hs.10615   ESTs   3.7   HMEC, HS578T_cells, Caco2       118768   N74467   Hs.94304   EST   3.68   HMEC, HS578T_cells, OVCAR_cells       114542   AA055768   Hs.122578   ESTs   3.66   EB_cells, MCF7, LNCaP_cells       101640   M58459   Hs.180911   ribasomal protein S4; Y-linked   3.62   DU145_cells, RPWE_2, A549_cells       107754   AA017462   Hs.187571   ESTs   3.6   HMEC (total RNA), Fibroblasts 2,                           Fibroblasts 2       104668   AA007312   Hs.183852   ESTs; Weakly similarto polymerase [H.sa   3.58   HMEC (total RNA), HMEC, Fibroblasts 2       135377   C21382   Hs.99768     H sapiens  mRNA; cDNA DKFZp564J0323   3.56   HMEC, HMEC (total RNA), EB_cells                   (from       127083   Z44079   Hs.91608   otoferlin   3.53   HMEC (total RNA), HMEC, Fibroblasts 2       102329   U35407   Hs.158084   peroxisome receptor 1   3.51   HMEC, HMEC (total RNA), EB_cells       117882   N50101   Hs.124724   ESTs; Weakly similar to coded for by C.   3.47   HMEC (total RNA), HMEC, EB_cells       126405   U46278   Hs.122489   ESTs   3.46   LNCaP_cells, MCF7, DU145_cells       131378   AA463886   Hs.203910   small glutamine-rich tetratricopeptide r   3.45   EB_cells, HMEC, HMEC (total RNA)       111418   R01084   Hs.19081   ESTs   3.43   HS578_Tcells, EB_cells, Lu_AD_H23       135398   AA194075   Hs.99908   nuclear receptor coactivator 4   3.4   HS578_Tcells, EB_cells, HMEC       108710   AA121960       zm24g9.sl Stratagene pancreas (#93728) H   3.4   EB_cells, HMEC, HMEC (total RNA)                   mRNA seq       105437   AA252191   Hs.25199   ESTs; Highly similar to match to ESTsAA   3.38   EB_cells, LNCaP_cells, RPWE_2       103448   X99133   Hs.204238   lipocalin 2 (oncogene 24p3)   3.38   PC3_cells, EB_cells, HT29_sells       130436   M84526   Hs.155597   D component of complement (adipsin)   3.37   PRSC_con, EB_cells, Lu_AD_H23       112309   R55021       yj76d5.s1 Soares breast 2NbHBst  H sapien     3.36   EB_cells, HMEC, HMEC (total RNA)       103211   X73079   Hs.205126   polymeric immunoglobulin receptor   3.35   MB231_cells, HT29_cells, Lu_SC_H69       109012   AA156576   Hs.191466   ESTs   3.21   EB_cells, HMEC, HMEC (total RNA)       129989   AF005887   Hs.247433   activating transcription factor 6   3.19   HMEC (total RNA), HMEC, Lu_AD_H23       113466   T86945   Hs.16304   ESTs   3.18   HMEC, MB231_cells, Caco2       103029   X54489   Hs.789   GRO1 oncogene (melanoma growth stimulati   3.16   Lu_LC_H460, PC3_cells, Fibroblasts 2       109374   AA218727   Hs.210785   ESTs; Highly similar to lbd1 [ H.sapiens ]   3.13   Caco2, A549_cells, MB231_cells       131403   R55750   Hs.26455   ESTs   3.13   HS578T_cells, HMEC, MB231_cells       113420   T83964   Hs.15400   ESTs   3.11   HMEC (total RNA), HMEC, EB_cells       112532   R69824   Hs.28313   ESTs   3.11   HMEC, HMEC (total RNA), EB_cells       117905   N50782   Hs.231713   EST   3.11   HMEC, HS578T_cells, Caco2       125349   T87826   Hs.164480   ESTs   3.1   HS578T_cells, EB_cells, MB-MDA-435s       107072   AA609113   Hs.177533     H sapiens  mRNA; cDNA DKFZp586N0318   3.1   Lu_SC_H69, MB-MDA-453, MB231_cells                   (from       118389   N64583   Hs.182365   ESTs   3.05   HMEC, HMEC, LNCaP_cells       117653   N38970   Hs.194214   ESTs   3.04   HMEC, HMEC (total RNA), Fibroblasts 2       101082   L05072   Hs.80645   interferon regulatory factor 1   3.04   EB_cells, PRSC_con, DU145_cells       126105   H75323   Hs.167614   ESTs   3.03   HS578T_cells, HMEC (total RNA), HMEC       120006   W90108   Hs.10848   KIAA0187 gene product   3.03   HMEC, HMEC (total RNA), EB_cells       127191   AA297581       EST113160 Gall bladder I  H sapiens  cDNA   3.02   HMEC, Lu_AD_H23, Lu_SQ_H520       106899   AA490107   Hs.21753   JM5 protein   3.02   EB_cells, HMEC (total RNA), HMEC       112784   R96306   Hs.191290   ESTs   3.02   EB_cells, HMEC, Lu_AD_358       113613   T93337   Hs.17167   ESTs; Highly similar to LRR FLI-l intera   3.02   HMEC (total RNA), EB_cells, HMEC       107631   AA007230   Hs.95026   ESTs   3.02   Lu_SC_H345, HS578T_cells, Lu_LC_H460       101923   S75256       HNL = neutrophil lipocalin [human, ovarian   3.01   PC3_cells, EB_cells, HT29_cells       100695   HG315T       Beta-1-Glycoprotein 11, Pregnancy-Specif   3.01   Fibroblasts 2, Lu_AD_H23, MB-MDA-435s       102523   U53445   Hs.15432   downregulated in ovarian cancer 1   2.98   PRSC_con, Fibroblasts 2, HMEC       121588   AA416615   Hs.98242   ESTs   2.94   HMEC, HS578T_cells, BT474_cells       103714   AA047055   Hs.192943   ESTs   2.94   HS578T_cells, EB_cells, HMEC       104916   AA056588   Hs.16542   ESTs   2.93   HMEC (total RNA), Fibroblasts 2, HMEC       109928   H05961   Hs.26331   ESTs   2.92   HMEC, MB231_cells, HS578T_cells       104586   R78309   Hs.20787   ESTs   2.92   Caco2, Lu_AD_358, Lu_AD_358       101236   L29433   Hs.47913   coagulation factor X   2.91   HMEC, HS578T_cells, Caco2       134749   L10955   Hs.89485   carbonic anhydrase IV   2.9   BT474_cells, MCF7, HMEC (total RNA)       124703   R07294   Hs.109108   solute carrier family 22 (organic cation   2.9   HMEC, HMEC (total RNA), MB-MDA-435s       114108   Z38431   Hs.27038   ESTs; Moderately similar to X-linkod ret   2.89   HMEC, HMEC (total RNA), EB_cells       107857   AA024687   Hs.61208   ESTs   2.88   HS578T_cells, MB231_cells, HMEC       111586   R10759   Hs.15177   ESTs   2.88   HS578T_cells, Lu_LC_H460, PRSC_con       127553   AA282433         H sapiens  p60 katanin mRNA; complete cds   2.87   EB_cells, MB-MDA-435s, RPWE_2       129881   AA458952   Hs.197728   ESTs; Weakly similar to ZINC FINGER PROT   2.86   EB_cells, PC3_cells, HMEC       116852   H65459   Hs.38323   ESTs   2.85   HMEC, Caco2, HS578T_cells       133468   X03068   Hs.73931   major histocompatibility complex; class   2.82   MB-MDA-435s, BT474_cells, HT29_cells       130998   C00810   Hs.21970   guanine nucleotide binding protein (G pr   2.82   LNCaP_cells, Lu_SC_H345, E8_cells       124075   H05741   Hs.101643   ESTs   2.82   HMEC, HS578T_cells, HT29_cells       128108   AI247422   Hs.129966   ESTs   2.82   HS578T_cells, Lu_LC_H1460, Lu_SC_H69       128096   R15413   Hs.164919   ESTs; Highly similarto PROTEIN KINASE C   2.8   MB231_cells, Lu_AD_H23, RPWE_2       126619   Z28861       HSBA7E032 STRATAGENE Human skeletal musc   2.77   HMEC, Lu_AD_H23, HMEC (total RNA)                   cDNA clone A7E03, mRNA seq.       114418   AA011383   Hs.177313   ESTs   2.77   HS578T_cells, EB_cells, MCF7       120383   AA228030   Hs.120234   ESTs   2.77   EB_cells, Fibroblasts 2, HMEC (total RNA)       126535   H73017   Hs.250723   ESTs; Weakly similar to atrophin-1 relat   2.76   Fibroblasts 2, PRSC_con, DU145_cells       119347   T64349       yc10d0B.s1 Stratagene lung (#937210) H s   2.76   EB_cells, Lu_AD_H23, Lu_SC_H69       126219   N36368   Hs.141438   ESTs; Moderately similar to similar to C   2.76   Lu_AD_H23, HMEC (total RNA), MB-MDA-435s       125426   R43963   Hs.169355   ESTs; Weakly similar to TRANSCRIPTION RE   2.75   HMEC, HMEC (total RNA), Lu_SC_H69       103005   X52008   Hs.2700   glycine receptor; alpha 2   2.74   HS578T_cells, HMEC, MB-MDA-453       109170   AA180352   Hs.191472   ESTs   2.74   Fibroblasts 2, HMEC (total RNA), MB-MDA-435s       101125   L10373   Hs.82749   transmembrane 4 superfamily member 2   2.73   Lu_LC_H460, 293T_cells, EB_cells       130656   Z20481   Hs.17411   KIAA0699 protein   2.73   HMEC (total RNA), HMEC, Fibroblasts 2       122933   AA476728   Hs.107537   ESTs   2.72   HMEC, EB_cells, HMEC (total RNA)       126033   AA055978   Hs.3807   ESTs; Weakly similar to PHOSPHOLEMMAN PR   2.71   Lu_SC_H345, Lu_SC_H69, 293T_cells       111644   R16539   Hs.223649   EST; Moderately similar to Cd-7 Metallo   2.71   EB_cells, HMEC, HMEC (total RNA)       133719   AA033790   Hs.75736   apolipoprotein D   2.71   Caco2, Fibroblasts 2, MB-MDA-435s       127555   AA582324   Hs.192857   ESTs   2.7   HMEC, HS578T_cells, HMEC (total RNA)       113321   T70580   Hs.13759   ESTs   2.69   HMEC (total RNA), Fibroblasts 2, PRSC_con       109326   AA210719   Hs.86414   ESTs   2.68   MB-MDA-435s, HS578T_cells, Lu_SC_H69       135003   H42527   Hs.92832   ESTs   2.68   HS578T_cells, EB_cells, PRSC_con       103650   Z70220         H.sapiens  mRNA for 5′UTR for unknown pro   2.68   HMEC, HS578T_cells, PRSC_con       111507   R07728   Hs.191218   ESTs   2.67   HMEC (total RNA), HMEC, EB_cells       117084   H93081   Hs.41829   ESTs   2.67   HS578T_cells, HMEC, MB231_cells       103975   AA306264   Hs.176403   ESTs; Moderately similar to !!!! ALU SUB   2.67   DU145_cells, HS578T_cells, MB-MDA-435s       132850   R89741   Hs.58215   ESTs; Moderately similar to rhotekin [M.   2.66   HS578T_cells, EB_cells, 293T_cells       121599   AA416770   Hs.98255   EST   2.61   HMEC (total RNA), HMEC, EB_cells       124230   H63111   Hs.6655   ESTs   2.6   HMEC (total RNA), HMEC, Fibroblasts 2       114174   Z39055   Hs.27264   ESTs; Moderately similar to !!!! ALU SUB   2.58   Caco2, MB-MDA-453, A549_cells       128469   T23724   Hs.258677   EST   2.57   Lu_LC_H460, Lu_SC_H69, MB-MDA-435s       117399   N26480   Hs.43805   lipoma HMGIC fusion partner-like 3   2.57   HMEC, HMEC (total RNA), EB_cells       129279   AA460551   Hs.184860   ESTs; Weakly similar to EG:87B1.6 [D.mel   2.57   HS578T_cells, EB_cells, HT29_cells       119817   W74257   Hs.159690   ESTs   2.57   HMEC, HMEC (total RNA), Lu_SC_H69       114445   AA019594   Hs.250493   ESTs; Weakly similar to KIAA0390 [ H.sapi     2.56   HMEC, HT29_cells, Lu_LC_H460       120651   AA287286   Hs.99657   ESTs   2.55   HMEC, HMEC (total RNA), Fibroblasts 2       105707   AA291012   Hs.37617   ESTs; Weakly similar to KIAA0727 protein   2.55   HMEC (total RNA), EB_cells, BT474_cells       128483   T58588   Hs.5148   FLN29 gene product   2.54   HMEC, HS578T_cells, MB231_cells       125890   AA448739   Hs.116708   ESTs; Weakly similar to HYPOTHETICAL PRO   2.54   HMEC (total RNA), HMEC, OVCAR_cells       134764   M74715   Hs.89560   iduronidase; alpha-L-   2.54   BT474_cells, PRSC_con, HT29_cells       113404   T82323   Hs.70337   immunoglobulin superfamily; member 4   2.54   Caco2, HS578T_cells, HMEC       129128   AA423854   Hs.108812   ESTs   2.54   BT474_cells, MB-MDA-435s, HMEC       101428   M19684   Hs.184929   protease inhibitor 1 (alpha-1-antitrypsi   2.54   HMEC, HT29_cells, HMEC (total RNA)       103206   X72755   Hs.77367   monokine induced by gamma interferon   2.53   Fibroblasts 2, MB231_cells, HMEC (total RNA)       132273   AA489716   Hs.43658   DKFZP586L151 protein   2.53   EB_cells, HMEC, HMEC (total RNA)       108392   AA075124       zm86a1.s1 Stratagene ovarian cancer (#93   2.52   HMEC (total RNA), HMEC, HS578T_cells                   IMAGE:544776 3′, mRNA seq       119508   W37895   Hs.45519   ESTs   2.52   Lu_SC_H69, CALU6_cells, 293T_cells       109828   F13763   Hs.19827   ESTs   2.52   PRSC_log, PRSC_con, HS578T_cells       135096   N89775   Hs.132390   zinc finger protein 36 (KOX 18)   2.51   HMEC, HS578T_cells, HT29_cells       130860   U66061   Hs.241395   protease; seine; 1 (trypsin 1)   2.51   OVCAR_cells, MB231_cells, PC3_cells       105725   AA292228   Hs.199791   STAT induced STAT inhibitor 3   2.51   HS578T_cells, HT29_cells, HMEC       110427   H48579   Hs.36275   EST   2.51   HS578T_sells, Caco2, Lu_LC_H460       123762   AA610013   Hs.244553   EST   2.51   HMEC (total RNA), HMEC, Fibroblasts 2       126406   AA034096       zi06f05.r1 Soares_fetal_liver_spleen_1NF   2.5   Lu_AD_H23, HS578T_cells, Lu_AD_358                   IMAGE:430017 5′, mRNA seq.       129751   AA346065   Hs.111286   KIAA0714 protein   2.5   HMEC, HS578T_cells, Fibroblasts 2       121704   AA418743   Hs.98306   ESTs   2.5   EB_cells, HMEC (total RNA), HMEC       112595   R77783   Hs.22404   protease; serine; 12 (neurotrypsin; moto   2.5   Fibroblasts 2, EB_cells, PRSC_son       108499   AA083103       zn1b12.s1 Stratagene hNT neuron (#937233   2.5   LNCaP_cells, MB-MDA-453, HMEC                   IMAGE:5477 3′, mRNA seq       131968   AA151333   Hs.36029   ESTs; Highly similar to basic helix-loop   2.5   Fibroblasts 2, A549_cells, 293T_cells       112665   R85661   Hs.221447   ESTs   2.48   Lu_AD_H23, HMEC, Lu_LC_H460       115764   AA421562   Hs.91011   anterior gradient 2 ( Xenepus laevis ) hom   2.48   EB_cells, Caco2, MCF7       105959   AA405540   Hs.7001   ESTs   2.48   OVCAR_cells, BT474_cells, Caco2       125804   R79519   Hs.16899   ESTs   2.48   HMEC (total RNA), EB_cells, HMEC       110102   H16681   Hs.180950   guanine nucleotide binding protein (G pr   2.46   HS578T_cells, HMEC, OVCAR_cells       104680   AA009809   Hs.37599   ESTs   2.46   HMEC, HS578T_cells, Caco2       132339   D80030   Hs.45127   chondroitin sulfate proteoglycan 5 (neur   2.45   OVCAR_cells, 293T_cells, HMEC (total RNA)       121712   AA419116   Hs.193663   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.45   Lu_SQ_H520, Lu_AD_H23 Lu_SC_H69       129226   M96843   Hs.180919   inhibitor of DNA binding 2; dominant neg   2.44   MB-MDA-453, 293T_cells, Caco2       128731   AF005271   Hs.104555   neuropeptide FF-amide peptide precursor   2.43   HMEC, HMEC (total RNA), EB_cells       106670   AA461174   Hs.5943   ESTs   2.43   EB_cells, HS578T_cells, Lu_SC_H69       119306   T26914   Hs.132785   EAP30 subunit of ELL complex   2.43   EB_cells, HMEC (total RNA), HMEC       133507   X74295   Hs.74369   integrin; alpha 7   2.42   Fibroblasts 2, Caco2, EB_cells       125713   AA367905   Hs.77356   transferrin receptor (p90; CD71)   2.41   HS578T_cells, Fibroblasts 2, Lu_AD_H23       107438   W27841   Hs.17118   ESTs; Weakly similar to B0025.2 ]C.elega   2.41   HMEC, HS578T_cells, MB231_cells       101784   M83186   Hs.114346   cytochrome c oxidase subunit VIIa polype   2.41   Fibroblasts 2, PRSC_con, PRSC_log       134578   AA194724   Hs.182418   endonuclease G   2.4   EB_cells, HMEC, Lu_AD_H23       125105   T95642   Hs.189759   ESTs   2.4   EB_cells, A549_cells, HS578T_cells       127067   AA380418   Hs.88012   SHP2 interacling transmembrane adaptor   2.4   HMEC, HMEC (total RNA), EB_cells       113118   T47906   Hs.220512   ESTs   2.39   MB-MDA-435s, HS578T_cells, HMEC       104791   AA029046   Hs.30377   ESTs; Moderately similar to dAMP inducib   2.39   LNCaP_cells, OVCAR_cells, PC3_cells       115833   AA428269   Hs.125035   ESTs   2.38   Caco2, LNCaP_cells, CALU6_cells       132223   R77451   Hs.4245   ESTs; Weakly similar to similar to S. ce   2.38   HMEC, HMEC (total RNA), EB_cells       115836   AA428863   Hs.89388   ESTs   2.38   HS578T_cells, HMEC, PRSC_con       101891   S45630   Hs.1940   crystallin; alpha B   2.38   HS578T_cells, OVCAR_cells, Lu_LC_H460       132894   D82422   Hs.5944   ESTs   2.37   Caco2, MB-MDA-453, HT29_cells       106939   AA496048   Hs.26570   ESTs   2.35   LNCaP_cells, 293T_cells, EB_cells       131104   W27770   Hs.258721   ESTs   2.35   HMEC (total RNA), HMEC, HT29_cells       122355   AA443789   Hs.189324   ESTs   2.34   HMEC (total RNA), HMEC, EB_cells       119343   T62873       yc3d2.s1 Stratagene lung (#93721)  H sapi     2.34   HS578T_cells, Lu_SC_H69, HT29_cells                   to contains Alu repetitive element;, mR       115442   AA284722   Hs.89121     H sapiens  mRNA; chromosome 1 specific tr   2.33   Lu_AD_H23, HMEC (total RNA), BT474_cells       134286   T69384   Hs.68398   period (Drosophila) homolog 1   2.33   HMEC, HMEC (total RNA), MB231_cells       125465   AI375276   Hs.158732   ESTs   2.33   HMEC (total RNA), EB_cells, HMEC       127449   AI421866   Hs.75722   ribophorin II   2.33   Lu_AD_H23, HMEC (total RNA), HMEC       110225   H23927   Hs.222381   ESTs   2.33   HS578T_cells, HMEC, Lu_LC_H460       119930   W86471   Hs.151624   hypocretin (orexin) receptor 2   2.32   HMEC, HMEC (total RNA), EB_cells       125958   AI073357   Hs.12311     H sapiens  clone 23570 mRNA seq   2.32   MB231_cells, HMEC (total RNA), HMEC       119746   W70279   Hs.221189   ESTs; Weakly similar to 15-HYDROXYPROSTA   2.32   HMEC, HS578T_cells, MB231_cells       108874   AA134112   Hs.107187     H sapiens  DNA seq from cosmid ICK072IQ o   2.32   Caco2, PRSC_con, LNCaP_cells                   L12 LIKE protein in an intron of the HS       127368   AA434362   Hs.193326   ESTs   2.32   HMEC (total RNA), HS578T_cells, HMEC       120437   AA243427   Hs.104311   ESTs   2.32   HMEC (total RNA), HMEC, MB-MDA-435s       119867   W80852   Hs.250696   KDEL (Lys-Asp-Glu-Leu) endoplasmic retic   2.32   Fibroblasts 2, HS578T_cells, MB-MDA-435s       131205   J02947   Hs.2420   superoxide dismutase 3; extracellular   2.32   PRSC_con, EB_cells, Lu_AD_358       133710   X76057   Hs.75694   mannose phosphate isomerase   2.31   293T_cells, LNCaP_cells, RPWE_2       104834   AA039331   Hs.16323   ESTs; Weakly similar to GAGE-7 [ H.sapien     2.31   Caco2, HS578T_cells, HMEC       113186   T56048   Hs.189674   ESTs   2.31   HMEC, Fibroblasts 2, HMEC (total RNA)       113462   T86826   Hs.142528   ESTs   2.31   PC3_cells, HS578T_cells, HMEC       104743   AA0211157   Hs.33619   ESTs   2.3   HMEC (total RNA), HMEC, OVCAR_cells       129687   Y00097   Hs.118796   annexin A6   2.3   PRSC_log, PRSC_con, HS578T_cells       111573   R10305   Hs.185683   ESTs   2.3   HMEC, HMEC (total RNA), EB_cells       117523   N32626   Hs.145532   ESTs; Weakly similar to Gag polyprotein   2.29   EB_cells, Fibroblasts 2, HS578T_cells       115540   AA349954   Hs.56281   ESTs; Weakly similar to ASB-1 protein [H   2.29   Fibroblasts 2, BT474_cells, MB231_cells       101622   M55621   Hs.151513   mannosyl (alpha-1;3-)-glycoprotein beta-   2.29   PRSC_con, RPWE_2, PRSC_log       103535   Y13620   Hs.122607   B-cell CLL/lymphoma 9   2.28   Lu_SC_H69, Lu_AD_358, Lu_AD_H23       127482   AI337294   Hs.155014   ESTs   2.28   HS578T_cells, 293T_cells, CALU6_cells       104297   D31111   Hs.106005   ESTs; Highly similar to NY-REN-50 antige   2.27   EB_cells, DU145_cells, HT29_cells       112318   R55470   Hs.11067   ESTs   2.27   MB-MDA-453, LNCaP_cells, OVCAR_cells       101877   M97496   Hs.778   guanylate cyclase activator 1B (retina)   2.27   HT29_cells, BT474_cells, Caco2       100760   HG3576       Major Histocompatibility Complex, Class   2.26   MB-MDA-435s, MB231_cells, BT474_cells       102362   U39412   Hs.75932   N-ethylmaleimide-sensitive factor attach   2.26   LNCaP_cells, MB-MDA-453, Caco2       106142   AA424590   Hs.239631   Golgi transport complex protein (90 kDa)   2.26   HMEC, HS578T_cells, Caco2       101461   M22430   Hs.76422   phospholipase A2; group IIA (platelets;   2.26   LNCaP_cells, BT474_cells, Caco2       119336   T55340   Hs.208238   ESTs   2.26   HS578T_cells, EB_cells, HMEC       127619   AA627122   Hs.163787   ESTS   2.25   Lu_SQ_H520, Lu_LC_H460, Lu_SC_H69       104113   AA427510   Hs.181202   ESTs; Weakly similar to Wiscott-Aldrich   2.25   MB-MDA-435s, Fibroblasts 2, HMEC (total RNA)       131219   C00476   Hs.24395   small inducible cytokine subfamily B (Cy   2.25   Lu_SQ_H520, BT474_cells, Fibroblasts 2       118915   N91481   Hs.54713   ESTs   2.25   HMEC (total RNA), HMEC, MCF7       127556   AA679831   Hs.190228   ESTs   2.24   HS578T_cells, EB_cells, HMEC       128700   U59286   Hs.103982   small inducible cytokine subfamily B (Cy   2.24   HMEC, HS578T_cells, Fibroblasts 2       113674   T96374   Hs.5753   Inositol(myo)-1(or 4)-monophosphatase 2   2.24   A549_cells, DU145_cells, Lu_AD_358       133085   M73720   Hs.646   carboxypeptidase A3 (mast cell)   2.24   HS578T_cells, Fibroblasts 2, HT29_cells       106017   AA411882   Hs.26268   ESTs   2.24   MB-MDA-453, OVCAR_cells, 293T_cells       100582   HG2348       Peptide Yy   2.24   HMEC, HS578T_cells, HMEC (total RNA)       134811   N66357   Hs.89761   ATP synthase; H+ transporting; mitochond   2.23   Lu_SQ_H520, LNCaP_cells, Lu_AD_H23       102543   U57627   Hs.234776   oculocerebrorenal syndrome of Lowe   2.23   293T_cells, EB_cells, LNCaP_cells       127357   AA452788       zx39g11.r1 Soares_total_fetus_Nb2HF8_9w   2.23   HS578T_cells, RPWE_2, HMEC (total RNA)                   IMAGE:788900 5′, mRNA seq.       135288   AA402930   Hs.97876   ESTs   2.23   HS578T_cells, 293T_cells, OVCAR_cells       105581   AA278850   Hs.28891   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.23   BT474_cells, BT474_cells, MB231_cells       103812   AA137107   Hs.124094   ESTs; Weakly similarto NFAT1-A [ M.muscu     2.23   Lu_SC_H345, Lu_AD_H23, PRSC_con       117016   H87171   Hs.52170   ESTs   2.22   Fibroblasts 2, Lu_LC_H460, HMEC (total RNA)       114607   AA079342   Hs.129057   breast carcinoma amplified seq 1   2.22   BT474_cells, HT29_cells, HT29_cells       134000   U29091   Hs.7833   selenium binding protein 1   2.22   LNCaP_cells, MB-MDA-453, BT474_cells       111069   N58461   Hs.22036   ESTs   2.22   HMEC, Lu_SC_H345, HS578T_cells       129048   L27670   Hs.108287   intercellular adhesion molecule 4; Lands   2.21   Lu_AD_H23, HS578T_cells, Lu_SQ_H520       124995   T52700   Hs.110044   ESTs   2.2   Caco2, MB-MDA-453, HT29_cehls       116678   F05063   Hs.251736   ESTs   2.2   HS578T_cells, BT474_cells, 293T_cells       118222   N62263   Hs.48501   EST   2.2   HS578T_cells, BT474_cells, MB231_cells       127888   AI149662   Hs.143590   ESTs   2.19   BT474_cells, CALU6_cells, MB231_cells       113790   W33178   Hs.26912   ESTs   2.19   HMEC, HMEC (total RNA), Fibroblasts 2       100097   AF002224         H sapiens  Angelman Syndrome Gene, E6-AP   2.19   HS578T_cells, CALU6_cells, 293T_cells                   from promoter P1, 5′UTR       109151   AA176800   Hs.73452   ESTs   2.19   CALU6_cells, Lu_AD_H23, Lu_SC_H69       135368   AA086057   Hs.9964   ribosomal protein; mitochondrial; S12   2.19   OVCAR_cells, A549_cells, Lu_AD_H23       109016   AA156936   Hs.58069   ESTs; Highly similar to type II cAMP-dep   2.19   HS578T_cells, BT474_cells, A549_cells       124300   H92575   Hs.105959   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.18   Lu_AD_358, Lu_SC_H69, Lu_SC_H345       123450   AA598913   Hs.111207   ESTs   2.18   HMEC (total RNA), HMEC, MB-MDA-435s       117435   N27628       yw50b08.s1 Weizmann Olfactory Epithelium   2.18   LNCaP_cells, DU145_cells, Lu_SQ_H520       119860   W80709   Hs.58485   ESTs   2.18   HS578T_cells, MB231_cells, Caco2       123833   AA620717   Hs.112889   ESTs   2.18   Lu_AD_H23, Lu_SQ_H520, Lu_AD_358       107936   AA029446   Hs.53115   ESTs   2.17   Caco2, 293T_cells, 293T_cells       119380   T83659   Hs.184407   ESTs   2.16   Lu_AD_H23, Lu_AD_358, PRSC_con       114066   Z38152   Hs.26920   ESTs   2.15   HMEC (total RNA), HMEC, EB_cells       128748   T59001   Hs.10475   ESTs   2.15   HMEC, HT29_cells, MB231_cells       130414   M21121   Hs.241392   small inducible cytokine A5 (RANTES)   2.15   HS578T_cells, PC3_cells, A549_cells       123490   AA599723       TAP binding protein (tapasin)   2.15   HS578T_cells, EB_cells, Lu_SC_H69       112588   R77302   Hs.20226   ESTs   2.14   HMEC (total RNA), HMEC, Fibroblasts 2       110548   H58715   Hs.14706   ESTs   2.14   HMEC, HMEC (total RNA), HT29_cells       101581   M34996   Hs.198253   major histocompatibility complex; class   2.14   MB-MDA-435s, HMEC, HMEC       115248   AA278887   Hs.194530   ESTs; Weakly similarto unknown [ H.sapie     2.14   HT29_cells, BT474_cells CALU6_cells       105619   AA280810   Hs.24003   ESTs; Moderately similar to LEYDIG CELL   2.14   Lu_SQ_H520, MB-MDA-435s, LNCaP_cells       128058   AI126617   Hs.132449   ESTs   2.14   HS578T_cells, EB_cells, HMEC (total RNA)       134573   AA442125   Hs.171873   ESTs; Weakly similar to PUTATIVE STEROID   2.14   EB_cells, MB231_cells, Caco2       134863   AA353903   Hs.183373   ATX1 (antioxidant protein 1; yeast) homo   2.14   Lu_SC_H345, HT29_cells, BT474_cells       128811   H17317   Hs.169100   ESTs; Weakly similar to HPBRII-7 protein   2.13   Caco2, Lu_SC_H345, EB_cells       112368   R59371   Hs.26653   EST   2.13   HMEC, HMEC (total RNA), Lu_SQ_H520       108395   AA075144       zm86f6.s1 Stratagene ovarian cancer (#93   2.13   HMEC (total RNA), HMEC, OVCAR_cells                   gb:X1664 TRANSLATIONALLY CONTROLLED TUM       129611   D45680   Hs.11614   ESTs   2.13   HMEC, HS578T_cells, Caco2       101253   L34355   Hs.99931   sarcoglycan; alpha (50 kD dystrophin-asso   2.12   HS578T_cells, OVCAR_cells, CALU6_cells       126701   AA515212   Hs.202590   ESTs; Weakly similar to mucin glycoprote   2.12   EB_cells, Lu_AD_H23, Lu_AD_H23       111628   R15825   Hs.4014   KIAA0940 protein; Huntingtin interacting   2.12   A549_cells, BT474_cells, MB-MDA-435s       108675   AA115240   Hs.61816   ESTs   2.12   Lu_AD_H23, MB-MDA-453, PRSC_con       127131   Z44658   Hs.105460   DKFZP564O0823 protein   2.12   EB_cells, Lu_SC_H69, Lu_SC_H69       109590   F02465   Hs.27281   ESTs   2.12   HMEC, HS578T_cells, HMEC (total RNA)       116539   D12124   Hs.242890   EST   2.12   Lu_AD_H23, Caco2, BT474_cells       112117   R45402   Hs.23789   ESTs   2.12   EB_cells, Lu_AD_H23, Lu_SQ_H520       126367   AA477929   Hs.25584   ESTs   2.12   Lu_SC_H69, Lu_AD_H23, Lu_AD_358       135252   U62966   Hs.97207   solute carrier family 28 (sodium-coupled   2.11   MB-MDA-435s, 293T_cells, CALU6_cells       117565   N34301   Hs.248426   EST   2.11   HMEC, HS578T_cells, MB231_cells       129430   AA258842   Hs.197877     H sapiens  clone 23777 putative transmemb   2.11   HS578T_cells, Lu_AD_358, MB-MDA-435s       120256   AA169801       sema domain; immunoglobulin domain (lg);   2.11   HMEC, HMEC (total RNA), EB_cells       134169   D20342   Hs.178137   transducer of ERBB2; 1 (TOB1)   2.11   HMEC (total RNA), 293T_cells, OVCAR_cells       130397   AA487452   Hs.155344   DNA fragmentation factor; 45 kD; alpha s   2.11   293T_cells, Caco2, Lu_AD_H23       132859   D20925   Hs.5842   ESTs   2.11   HMEC (total RNA), Fibroblasts 2, HMEC       117633   N36404   Hs.44807   ESTs   2.11   HMEC, Caco2, HS578T_cells       125003   T59442   Hs.100445   ESTs   2.11   MB-MDA-435s, HMEC (total RNA), HT29_cells       125329   AA825437   Hs.58875   ESTs   2.11   HS578T_cells, PRSC_con, PRSC_log       114065   Z38149   Hs.134015   uronyl 2-sulfotransferase   2.11   MB-MDA-435s, 293T_cells, PRSC_con       120718   AA292747   Hs.97296   ESTs   2.11   HT29_cells, Lu_AD_H23, Lu_SC_H69       133869   T49444   Hs.77031   Sp2 transcription factor   2.1   Lu_LC_H460, Lu_AD_358, RPWE_2       135351   AA430179   Hs.9933   putative Ac-like transposon   2.1   HS578T_cells, EB_cells, HMEC       110973   N51529   Hs.118047   ESTs   2.09   EB_cells, HS578T_cells, MCF7       131879   AA017161   Hs.33792   ESTs   2.09   HMEC (total RNA), MB231_cells, BT474_cells       116656   F03935   Hs.241640   EST   2.09   HS578T_cells, Lu_LC_H460, Lu_SC_H69       120311   AA194074   Hs.193401   ESTs   2.09   OVCAR_cells, HMEC (total RNA), HMEC       108024   AA040433   Hs.61898   DKFZP586N2124 protein   2.09   HMEC (total RNA), BT474_cells, HT29_cells       105871   AA399633   Hs.24872   ESTs   2.09   Fibroblasts 2, A549_cells, HS578T_cells       120206   Z40805   Hs.91668   ESTs   2.09   BT474_cells, MB-MDA-453, EB_cells       112333   R56222   Hs.26514   ESTs   2.09   Lu_AD_H23, Fibroblasts 2, Lu_LC_H460       116746   H04811   Hs.79027   ESTs   2.08   MB-MDA-435s, HMEC (total RNA), Lu_SC_H345       121529   AA412257   Hs.98121   ESTs   2.08   HMEC, HMEC (total RNA), HS578T_cells       105592   AA279337   Hs.180549   ESTs; Highly similar to R26660_1; partia   2.08   LNCaP_cells, PRSC_log, PRSC_log       108582   AA088231   Hs.91732   ESTs   2.08   HS578T_cells, Lu_SC_H345, Lu_SC_H69       123197   AA489250   Hs.59403   serine palmitoyltransferase; subunit II   2.08   EB_cells, Lu_SC_H69, Lu_SC_H345       134965   J05480   Hs.92   protein phosphatase 3 (formerly 2B); cat   2.08   LNCaP_cells, MB-MDA-435s, HMEC       123856   AA620814   Hs.144959   ESTs   2.08   HS578T_cells, BT474_cells, BT474_cells       132058   AA251737   Hs.172818   Apg12 (autophagy 12;  S. cerevisiae )-like   2.07   HS578T_cells, MCF7, HMEC       126476   R94666   Hs.195155   ESTs; Weakly similar to transporter prot   2.07   PRSC_log, Lu_LC_H460, RPWE_2       106087   AA418740   Hs.21111   ESTs   2.07   OVCAR_cells, A549_cells, Lu_AD_H23       103802   AA122003   Hs.62954   ferritin; heavy polypeptide 1   2.07   HMEC, HMEC (total RNA), HS578T_cells       125633   AA908225   Hs.126641   ESTs   2.07   EB_cells, Flbroblasts 2, Lu_SC_H69       112817   R98491   Hs.14584   ESTs   2.07   HMEC, HMEC (total RNA), Fibroblasts 2       111050   N56984   Hs.74335   heat shock 90 kD protein 1; beta   2.07   LNCaP_cells, DU145_cells, 293T_cells       133072   AA425294   Hs.64322   ESTs; Weakly similar to Closely related   2.07   LNCaP_cells, MB-MDA-453, Caco2       118270   N62868   Hs.48653   ESTs   2.07   HMEC (total RNA), HMEC, EB_cells       105035   AA128406   Hs.8859   ESTs   2.07   LNCaP_cells, PC3_cells, EB_cells       102337   U36922       Human fork head domain protein (FKHR) mR   2.07   293T_cells, HMEC, HT29_cells       109687   F09380   Hs.182859   lifeguard   2.06   BT474_cells, BT474_cells, Lu_AD_H23       109802   F10789   Hs.12439   ESTs   2.06   EB_cells, EB_cells, Caco2       128103   AA905960   Hs.48516   ESTs   2.06   HT29_cells, HMEC (total RNA), HMEC       128278   AI018343   Hs.131275   ESTs   2.06   PRSC_con, Lu_SC_H345, HS578T_cells       131873   H39997   Hs.33716   ESTs   2.08   HMEC (total RNA), HMEC, EB_cells       122683   AA455528   Hs.96772   ESTs   2.05   LNCaP_cells, Lu_AD_H23, HS578T_cells       128066   AA884838   Hs.189171   ESTs   2.05   HMEC, HUEC (total RNA), Fibroblasts 2       131451   N28028   Hs.26968     H sapiens  mRNA from chromosome 5q21-22;   2.05   MB-MDA-435s, Lu_LC_H460, Lu_SQ_H520       120887   AA365644   Hs.97043   ESTs   2.05   HS578T_cells, PRSC_con, HMEC       103966   AA303166   Hs.127270   ESTs   2.05   HMEC (total RNA), LNCaP_cells, PC3_cells       105861   AA399260   Hs.28454   ESTs   2.05   Fibroblasts 2, HMEC (total RNA), EB_cells       104627   AA001976   Hs.19603   ESTs   2.05   HS578T_cells, HMEC, BT474_cells       108794   AA129468   Hs.203392   ESTs   2.04   HS578T_cells, HMEC, A549_cells       111896   R38936   Hs.24894     H sapiens  clone 25248 mRNA seq   2.04   HS578T_cells, PC3_cells, 293T_cells       101849   M94167   Hs.172816   neuregulin 1   2.04   HMEC, HS578T_cells, HMEC (total RNA)       119913   W85931   Hs.58785   ESTs   2.04   HMEC, BT474_cells, MB231_cells       130785   AA242826   Hs.19405   caspase recruitment domain 4   2.04   HMEC, HS578T_cells, BT474_cells       124702   R06984   Hs.7745   ESTs; Weakly similar to TESTIS-SPECIFIC   2.03   Fibroblasts 2, PRSC_con, HMEC       105769   AA478001   Hs.225935   diacylglycerol O-acyltransferase (mouse)   2.03   PC3_cells, EB_cells, HS578T_cells       132219   N48682   Hs.172971   ESTs   2.03   HT29_cells, PC3_cells, A549_cells       122033   AA431334   Hs.109297   ESTs   2.03   OVCAR_cells, A549_cells, Caco2       120461   AA251301       zs10b02.s1 NCI_CGAP_GCB1  H sapiens  cDNA   2.03   HS578T_cells, EB_cells, EB_cells                   contains Alu repetitive element;, mRNA       134959   U90550   Hs.91813   butyrophilin; subfamily 2; member A2   2.03   HMEC, Fibroblasts 2, EB_cells       104909   AA055892   Hs.14543   ESTs   2.03   Lu_SC_H345, PC3_cells, DU145_cells       101950   S79219   Hs.80741   propionyl Coenzyme A carboxylase; alpha   2.03   Lu_SC_H69, EB_cells, CALU6_cells       133878   D78947   Hs.7718   ESTs; Weakly similar to weak similarity   2.02   EB_cells, MCF7, MB231_cells       103459   X99894   Hs.32938   insulin promoter factor 1; homeodomain t   2.02   EB_cells, Lu_AD_H23, Lu_AD_358       125507   AI436377   Hs.258590   tetraspanin TM4-B   2.02   A549_cells, Lu_SQ_H520, Lu_AD_H23       116857   F04014   Hs.65996   ESTs   2.01   HS578T_cells, HMEC, MB231_cells       112920   T10234   Hs.4275   ESTs   2.01   HS578T_cells, EB_cells, PRSC_con       105533   AA258572   Hs.6418   ESTs; Moderately similar to seven transm   2.01   HS578T_cells, HMEC, EB_cells       126762   AA064671       zm13b04.r1 Stratagene pancreas (#937208)   2.01   RPWE_2, Lu_AD_H23, Lu_AD_358                   similar to TR:G413842 G413842 NONCLASSI       128999   R37808   Hs.107765   ESTs   2.01   HS578T_cells, OVCAR_cells, EB_cells       133902   AA114858   Hs.7745   ESTs; Weakly similar to TESTIS-SPECIFIC   2   Fibrablasts 2, PRSC_con, DU145_cells                  
 
     [0328]                           TABLE 2                                      Pkey:   Unique Eos probeset identifier number           ExAccn:   Exemplar Accession number, Genbank accession number           UnigeneID:   Unigene number           Unigene Title:   Unigene gene title                                     Pkey   Ex Accn   UniG_ID   Complete_Title   Ratio Mets/BS   Top 3 expressing cell lines                                             101447   M21305   Hs.247946   Human alpha satellite and satellite 3 ju   110.98   EB_cells, Fibroblasts2, A549_cells       105039   AA130349   Hs.36475   ESTs   9.13   EB_cells, OVCAR_cells, Lu_SC_H345       106094   AA419461   Hs.18127   ESTs   8.51   H729_cells, MB-MDA-453, HS578T_cells       105777   AA348412   Hs.23096   ESTs   8.4   293T_cells, OVCAR_cells, EB_cells       129818   N54841   Hs.172572   ESTs   7.2   Lu_SC_H69, EB_cells, Lu_SC_H345       118475   N66845   Hs.165411   ESTs; Weakly similar to !!!! ALU CLASS B   7   DU145_cells, EB 13  cells, Caco2       112170   R48744   Hs.192878   ESTs   6.91   293T_cells, DU145_cells, HT29_cells       114918   AA236813   Hs.72324   ESTs; Highly simharto unknown [ H.sapie     6.6   EB_cells, 293T_cells, DU145_cells       104590   R79750   Hs.83623   nuclear receptor subfamily 1; group I; m   6.58   293T_cells, OVCAR_cells, HMEC       120625   AA285053   Hs.107168   ESTs   6.55   CALU6_cells, OVCAR_cells, EB_cells       115650   AA404564   Hs.47094   ESTs   6.43   EB_cells, LNCaP_cells, Lu_SC_H345       124568   N67086   Hs.102000   ESTs   6.35   PC3_cells, A549_cells, DU145_cells       134238   R81509   Hs.184571   splicing factor arginine/serine-rich 11   6.32   293T_cells, Lu_SC_H345, HMEC       114721   AA131450   Hs.103822   ESTs   6.13   Caco2, MB-MDA-435s, PRSC_log       106145   AA424791   Hs.5734   KIAA0679 protein   6   OVCAR_cells, EB_cells, 293T_cells       114610   AA081079       zn32h9.s1 Stratagene endothelial cell 93   5.97   PRSC_con, DU145_cells, HS578T_cells                   IMAGE:549185 3′, mRNA seq       130281   R12777   Hs.15395   ESTs; Weakly similar to ARGINYL-TRNA SYN   5.94   PRSC_con, HT29_cells, EB_cells       124690   R05818   Hs.173830   ESTs   5.92   LNCaP_cells, EB_cells, OVCAR_cells       113490   T88700   Hs.173374   ESTs   5.81   DU145_cells, PC3_cells, HMEC (total RNA)       104425   H88496   Hs.40583   ESTs   5.77   OVCAR_cells, HS578T_cells, A549_cells       118828   N79496   Hs.50824   EST   5.45   LNCaP_cells, OVCAR_cells, DU145_cells       129076   AA262179   Hs.169343   ESTs   5.35   293T_cells, BT474_cells, MCF7       109684   F09317   Hs.140885   ESTs; Weakly similar to LINE-1 REVERSE T   5.34   Fibroblasts 2, Lu_SC_H69, DU145_cells       104558   R56678   Hs.88959   Human DNA seq from clone 967N21 on chr 2   5.32   EB_cells, PC3_cells, Lu_SC_H345                   part of KIAA0172; the gene for a novel       109032   AA158234   Hs.72222   ESTs   5.23   HT29_cells, PC3_cells, Lu_AD_358       129350   U50535   Hs.110630   Human BRCA2 region: mRNA seq CG006   5.2   293T_cells, EB_cells, DU145_cells       112662   R85436   Hs.193150   ESTs   5.2   MB-MDA-435s, PRSC_con, MB-MDA-453       132902   AA490969   Hs.168147   ESTs   5.18   PC3_cells, LNCaP_cells, CALU6_cells       126872   AA136653       ESTs   5.04   EB_cells, Fibroblasts 2, A549_cells       122528   AA449804   Hs.250992   EST   5.04   Lu_SC_H345, PRSC_con, LNCaP_cells       102193   U20758   Hs.313   secreted phosphoprotein 1 (osteopontin;   5.02   Lu_LC_H460, A549_cells, MB-MDA-435s       121332   AA404384   Hs.97921   ESTs   5.01   EB 13  cells, Lu_SC_H69, DU145_cells       135357   AA235803   Hs.79572   cathepsin D (lysosomal aspartyl protease   4.96   EB_cells, MCF7, DU145_cells       109141   AA176428   Hs.193380   ESTs   4.86   DU145_cells, PC3_cells, PRSC_log       135324   AA082041   Hs.9873   ESTs   4.83   EB_cells, Lu_SC_H345, HS578T_cells       124875   R70506   Hs.207693   ESTs; Weakly similar to !!!! ALU SUBFAMI   4.75   DU145_cells, OVCAR_cells, LNCaP_cells       102380   U40434   Hs.155981   mesothelin   4.71   OVCAR_cells, Lu_AD_H23, RPWE_2       127956   AA826117   Hs.194013   ESTs   4.69   EB_cells, HS578T_cells, DU145_cells       125038   T78089   Hs.168887   ESTs   4.58   OVCAR_cells, 293T_cells, DU145_cells       102515   U52696       Humn adrenal Creb-rp hmlg (Creb-rp), com   4.57   Lu_SC_H345, Lu_SC_H69, HT29_cells       109027   AA157818   Hs.238380   Human endogenous retroviral protease mRN   4.57   PC3_cells, EB_cells, Lu_SQ_H520       115096   AA255991   Hs.175319   ESTs   4.57   OVCAR_cells, 293T_cells, PC3_cells       123470   AA599106   Hs.194208   ESTs   4.55   LNCaP_cells, Lu_SC_H69, 293T_cells       113219   T59257   Hs.194407   ESTs   4.55   A549_cells, 293T_cells, 293T_cells       123433   AA598661   Hs.112478   ESTs   4.55   EB_cells, OVCAR_cells, HT29_cells       135182   M28170   Hs.96023   CD19 antigen   4.53   OVCAR_cells, DU145_cells, EB_cells       121721   AA419470   Hs.199961   ESTs   4.51   DU145_cells, LNCaP_cells, EB_cells       129126   H88486   Hs.108806   ESTs   4.45   LNCaP_cells, Caco2, EB_cells       135232   AA342457   Hs.96800   ESTs; Moderately similar to !!!! ALU SUB   4.43   LNCaP_cells, DU145_cells, OVCAR_cells       124847   R60044   Hs.106706   ESTs; Highly similar to BETA-CATENIN [H.   4.42   OVCAR_cells, CALU6_cells, CALU6_cells       110349   H40988       ESTs; Weakly similar to !!!! ALU SUBFAMI   4.39   DU145_cells, OVCAR_cells, LNCaP_cells       134402   U25165   Hs.82712   fragile X mental retardation; autosomal   4.38   HS578T_cells, OVCAR_cells, DU145_cells       115494   AA290603   Hs.256517   ESTs   4.36   Lu_SC_H345, OVCAR_cells, PC3_cells       119174   R71234       yi54c08.s1 Soares placenta Nb2HP  H sapie     4.33   DU145_cells, OVCAR_cells, LNCaP_cells                   transcript (rRNA); gb:541458 ROD CGMP-                   BETA-SUBUNIT (HUMAN); contain       121943   AA429265   Hs.126759   ESTs   4.3   EB_cells, HT29_cells, Lu_SC_H69       110856   N33063   Hs.23291   ESTs; Weakly similar to S164 [ H.sapiens ]   4.28   OVCAR_cells, EB_cells, Lu_SC_H69       102474   U49973       Human Tigger1 transposable element comp   4.28   DU145_cells, LNCaP_cells, OVCAR_cells       123458   AA598963   Hs.112499   KIAA0612 protein   4.27   A549_cells, A549_cells, BT474_cells       116459   AA621399   Hs.64193   ESTs   4.22   Caco2, HS578T_cells, MB-MDA-435s       126301   N62371   Hs.100043   ESTs; Weakly similar to Similar to cutic   4.22   PC3_cells, DU145_cells, Lu_SC_H345       123461   AA598990   Hs.251119   EST   4.22   Lu_SC_H345, Lu_SC_H69, OVCAR_cells       130588   AA287735   Hs.16411   Human DNA seq from done 1189B24 on chro   4.2   EB_cells, LNCaP_cells, MCF7                   MLRQ subunit (EC 1.6.5.3; EC 1.6.99.3;                   Tyrosine-protein Kinase FER (EC 2.7.1.1       125756   W25498   Hs.81634   ATP synthase; H + transporting; mitochond   4.2   HMEC, EB_cells, DU145_cells       135009   AA040507   Hs.251865   ESTs   4.19   293T_cells, EB_cells, DU145_cells       107001   AA598589   Hs.24492   ESTs   4.18   293T_cells, DU145_cells, EB_cells       124896   R82063   Hs.101594   EST   4.16   OVCAR_cells, Lu_SC_H345, HMEC (total RNA)       119404   792950       ye27c10.s1 Stratagene lung (#937210) H s   4.15   DU145_cells, PC3_cells, Fibroblasts 2       125090   T91518       ye20f05.s1 Stratagene lung (#937210) H s   4.14   LNCaP_cells, DU145_cells, OVCAR_cells                   contains Alu repetitive element; contain       117348   N24157   Hs.139615   ESTs   4.1   Lu_SC_H345, Lu_SC_H69, PRSC_log       111389   N95837   Hs.169111   ESTs; Weakly similar to LB2A [D.melanoga   4.1   DU145_cells, MCF7, LNCaP_cells       134977   AA464698   Hs.19390   ESTs; Weakly similar to bullous pemphigo   4.09   OVCAR_cells, Fibroblasts 2, Lu_SC_H69       124696   R06273   Hs.186467   ESTs; Moderately similar to !!!! ALU SUB   4.09   OVCAR_cells, Lu_SC_H345, PRSC_con       124090   H09570   Hs.143032   ESTs; Weakly similar to neuronal thread   3.98   DU145_cells, OVCAR_cells, Lu_SC_H345       133992   R46354   Hs.169832   zinc finger protein 42 (myeloid-speciflc   3.98   HT29_cells, MB231_cells, BT474_cells       126009   H51652   Hs.242985   hemoglobin; gamma G   3.96   Lu_SC_H69, OVCAR_cells, EB_cells       114161   Z38904   Hs.22385   ESTs; Weakly similar to KIAA0970 protein   3.94   HS578T_cells, EB_cells, PRSC_con       109171   AA180356   Hs.73700   EST   3.94   293T_cells, MB-MDA-435s, A549_cells       122007   AA430629   Hs.98564   ESTs   3.93   PC3_cells, A549_cells, OVCAR_cells       131936   AA094865   Hs.179972   interferon; alpha-inducible protein (clo   3.9   CALU6_cells, EB_cells, Lu_SC_H69       128668   AA194849   Hs.103422   ESTs   3.9   Lu_AD_H23, EB_cells, Lu_SC_H69       124977   T33859   Hs.190452   KIAA0365 gene product   3.89   293T_cells, DU145_cells, EB_cells       107048   AA600012   Hs.10669   ESTs; Moderately similarto KIAA0400 [H.   3.89   PC3_cells, HS578T_cells, DU145_cells       105358   AA236034   Hs.25362   ESTs   3.89   Caco2, EB_cells, CALU6_cells       135106   AA599037   Hs.9456   SWI/SNF related; matrix assocd; actin de   3.86   EB_cells, LNCaP_cells, Caco2       106686   AA463215   Hs.29896   ESTs; Weakly similar to proline-rich pro   3.85   OVCAR_cells, DU145_cells, EB_cells       132093   AA400091   Hs.39421   ESTs   3.85   OVCAR_cells, OVCAR_cells, LNCaP_cells       128651   AA446990   Hs.103135   ESTs   3.84   EB_cells, LNCaP_cells, OVCAR_cells       102459   U48936       Human amiloride-sensitive epithelial sod   3.84   HT29_cells, BT474_cells, Lu_SC_H69       113732   798288   Hs.193295   ESTs; Weakly similar to !!!! ALU SUBFAMI   3.82   DU145_cells, OVCAR_cells, LNCaP_cells       116000   AA448710   Hs.41327   ESTs   3.82   DU145_cells, MB-MDA-453, Lu_SC_H69       120748   AA303153   Hs.237994   EST; Weakly similarto !!!! ALU SUBFAMIL   3.82   DU145_cells, DU145_cells, Lu_SC_H345       116318   AA490830   Hs.58570   deleted in cancer 1; RNA helicase HDB/DI   3.79   MB-MDA-453, CALU6_cells, EB_cells       114366   Z41747   Hs.469   succinate dehydrogenase complex; subunit   3.78   DU145_cells, Fibroblasts 2, Caco2       107248   D59894   Hs.34782   ESTs   3.75   LNCaP_cells, DU145_cells, EB_cells       132713   AA286906   Hs.55335   ESTs   3.75   OVCAR_cells, EB_cells, Lu_SC_H345       102222   U24683   Hs.159386   Immunoglobulin heavy variable 4-4   3.73   EB_cells, OVCAR_cells, 293T_cells       108201   AA057518   Hs.63394   ESTs   3.72   293T_cells, DU145_cells, EB_cells       119940   W86779   Hs.171807   DKFZP586B0319 protein   3.71   EB_cells, Caco2, DU145_cells       106508   AA452590   Hs.30348   ESTs   3.67   EB_cells, LNCaP_cells, 293T_cells       114360   Z41592   Hs.22129   hypothetical protein   3.67   HT29_cells, Lu_SQ_H520, Lu_SQ_H520       100991   J03764   Hs.82085   plasminogen activator inhibitor; type I   3.67   Fibroblasts 2, HS578T_cells, MB231_cells       107580   AA002091   Hs.175476   ESTs; Weakly similar to !!!! ALU SUBFAMI   3.67   OVCAR_cells, LNCaP_cells, Lu_SC_H345       111685   R21408   Hs.106095   ESTs   3.66   OVCAR_cells, A549_cells, 293T_cells       128336   AI242720   Hs.146043   ESTs; Weakly similar to alternatively sp   3.66   Lu_SC_H345, Caco2, OVCAR_cells       130868   AA004900   Hs.171917   ESTs; Weakly similar smlr to glycerophos   3.61   EB_cells, HS578T_cells, LNCaP_cells       116802   H44061   Hs.194026   ESTs   3.6   Lu_SC_H345, OVCAR_cells, DU145_cells       130753   Z46632   Hs.189   phosphodiesterase 40; cAMP-specific (dun   3.6   Lu_SC_H69, Lu_AD_H23, Lu_SC_H345       123074   AA485117   Hs.105653   ESTs   3.6   293T_cells, MB231_cells, Fibroblasts 2       114317   Z41038   Hs.469   succinate dehydrogenase complex; subunit   3.6   DU145_cells, HS578T_cells, CALU6_cells       134194   AA233231   Hs.79828   ESTs   3.59   BT474_cells, MB231_cells, HT29_cells       127752   AA808388   Hs.211167   ESTs   3.59   Lu_SQ_H520, MB-MDA.435s, DU145_cells       123526   AA608657       ESTs; Moderately similar to !!!! ALU SUB   3.59   DU145_cells, OVCAR_cells, LNCaP_cells       127917   AA211895   Hs.118831   EST; Highly similar to dJ1163J1.2.1 [H.s   3.58   Lu_SC_H345, OVCAR_cells, PRSC_con       105941   AA404427   Hs.10669   ESTs; Moderately similar to KIAA0400 [H.   3.58   PC3_cells, DU145_cells, HS578T_cells       124694   R06108   Hs.135258   ESTs   3.56   Lu_AD_H23, Lu_SQ_H520, Lu_AD_358       105658   AA282571   Hs.203772   FSHD region gene 1   3.56   DU145_cells, EB_cells, A549_cells       111168   N66951   Hs.238380   Human endogenous retroviral protease mRN   3.55   PC3_cells, EB_cells, MB231_cells       133254   AA156670   Hs.180780     H sapiens  agrin precursor mRNA; partial   3.54   OVCAR_cells, DU145_cells, PC3_cells       132840   U33821       Tax1 (human 7-cell leukemia virus type I   3.53   MB231_cells, CALU6_cells, BT474_cells       116562   D25807   Hs.90145   ESTs   3.52   MB231_cells, BT474_cells, Lu_SC_H345       126045   N80361   Hs.14248   ESTs   3.51   DU145_cells, Lu_SC_H345, OVCAR_cells       122878   AA465341   Hs.99640   ESTs   3.47   HT29_cells, OVCAR_cells, HMEC       105220   AA210695   Hs.17212   ESTs   3.47   MB-MDA-435s, HT29_cells, HT29_cells       127001   AA731636   Hs.59319   ESTs; Weakly similar to !!!! ALU SUBFAMI   3.45   LNCaP_cells, DU145_cells, Lu_SC_H345       112693   R88741   Hs.91065   ESTs; Moderately similar to proliferatio   3.44   EB_cells, LNCaP_cells, DU145_cells       104935   AA063280   Hs.35552   ESTs   3.43   LNCaP_cells, CALU6_cells, 293T_cells       128710   J04813   Hs.104117   cytochrome P450; subfamily IIIA (niphedi   3.41   HT29_cells, A549_cells, Fibroblasts 2       131996   D86956   Hs.36927   heat shock 105 kD   3.4   EB_cells, PC3_cells, Lu_SC_H345       119229   T03229         H sapiens  (clone 104) retinoblastoma 1 g   3.4   DU145_cells, Lu_SC_H345, EB_cells       128046   AA873285   Hs.137947   ESTs   3.39   EB_cells, LNCaP_cells, DU145_cells       105175   AA186804   Hs.25740   ESTs; Weakly similar to ubiquitous TPR m   3.39   PC3_cells, MCF7, DU145_cells       132349   Y00705   Hs.181286   serine protease inhibitor; Kazal type 1   3.38   Caco2, EB_cells, Lu_SC_H69       101569   M32053       Human H19 RNA gene, complete cds   3.37   Lu_SC_H69, MCF7, OVCAR_cells       116389   AA599011       troponin T1; skeletal; slow   3.36   DU145_cells, LNCaP_cells, OVCAR_cells       130641   AA182001   Hs.17155   ESTs   3.36   DU145_cells, MB-MDA-435s, HS578T_cells       109362   AA214615   Hs.194348   ESTs   3.33   HT29_cells, Fibroblasts 2, BT474_cells       106278   AA432292   Hs.23388   ESTs; Moderately similar to !!!! ALU SUB   3.33   EB_cells, Fibroblasts 2, BT474_cells       127241   AA321849   Hs.248340     H sapiens  mRNA; cDNA DKFZp564J2116 (from   3.32   LNCaP_cells, DU145_cells, EB_cells       133339   N64588   Hs.71252   ESTs   3.32   DU145_cells, EB_cells, Caco2       113260   T64896   Hs.237992   ESTs   3.32   Lu_SQ_H345, LNCaP_cells, Lu_SC_H69       133349   N75791   Hs.7153   L-3-hydroxyacyl-Coenzyme A dehydrogenase   3.31   Caco2, EB_cells, OVCAR_cells       107149   AA621159   Hs.23284   ESTs   3.29   HS578T_coells, DU145_cells, PRSC_con       133195   AA350744   Hs.181409   KIAA1007 protein   3.29   EB_cells, Lu_AD_H23, Lu_AD_358       111302   N73838   Hs.15049   ESTs   3.29   DU145_cells, EB_cells, HS578T_cells       106414   AA447971   Hs.28827   ESTs   3.28   A549_cells, OVCAR_cells, PC3_cells       121768   AA421561   Hs.251664   insulin-like growth factor 2 (somatomedi   3.28   Caco2, PRSC_con, PRSC_log       117176   H98670   Hs.49753   ESTs; Weakly similar to hypothetical pro   3.28   PRSC_log, CALU6_cells, OVCAR_cells       131320   AA171948   Hs.145696   splicing factor(CC1.3)   3.28   EB_cells, LNCaP_cells, DU145_cells       100700   HG3227-H       Guanine Nucleotide-Binding Protein Hsr1   3.27   EB_cells, RPWE_2, Lu_AD_H23       134275   AA132328   Hs.3688   acid-inducible phosphoprotein   3.26   EB_cells, DU145_cells, LNCaP_cells       117667   N39214   Hs.44708   Ser-Thr protein kinase related to the my   3.26   LNCaP_cells, DU145_cells, MB-MDA-453       124889   R78604   Hs.101570   ESTs   3.25   Lu_AD_H23, Lu_SC_H69, Lu_SC_H345       126631   W95117   Hs.193337   ESTs   3.25   Lu_SC_H345, OVCAR_cells, Lu_SC_H69       105643   AA282069   Hs.173802   KIAA0603 gene product   3.24   Caco2, EB_cells, 293T_cells       132718   AA056731   Hs.554   Siogren syndrome antigen A2 (60 kD; ribon   3.24   CALU6_cells, OVCAR_cells, A549_cells       116417   AA609309   Hs.239302   ESTs; Weakly similar to !!!! ALU SUBFAMI   3.24   A549_cells, CALU6_cells, 293T_cells       108039   AA041341   Hs.46670   ESTs   3.24   293T_cells, EB 13  cells, Caco2       114116   Z38496   Hs.103283   KIAA0594 protein   3.23   DU145_cells, OVCAR_cells, EB_cells       124514   N58045   Hs.142737   ESTs   3.22   EB_cells, Caco2, Lu_SQ_H520       110802   N26651   Hs.252748   ESTs   3.22   LNCaP_cells, MB-MDA-435s, MB-MDA-453       106920   AA490899   Hs.24462   ESTs   3.22   DU145_cells, EB_cells, OVCAR_cells       123523   AA608588   Hs.193634   ESTs   3.21   DU145_cells, LNCaP_cells, OVCAR_cells       131564   AA491465   Hs.28792   ESTs   3.2   HS578T_cells, HMEC (total RNA), HMEC       119423   T99544   Hs.173734   ESTs; Weakly similar to !!!! ALU CLASS B   3.2   EB_cells, DU145_cells, Caco2       128736   F03934   Hs.104607   ESTs   3.19   PC3_cells, Lu_SQ_H520, Lu_SC_H69        101511   M27826   Hs.238380   Human endogenous retroviral protease mRN   3.18   PC3_cells, DU145_cells, Lu_SQ_H520       114509   AA043551   Hs.95249   ESTs   3.18   EB 13  cells, Lu_SC_H345, DU145_cells       124196   H52617   Hs.144167   ESTs   3.17   BT474_cells, MB231_cells, HMEC       129095   L12350   Hs.108623   thrombospondin 2   3.17   Fibroblasts 2, PRSC_con, PRSC_log       116457   AA621367   Hs.119683   ESTs   3.17   293T_cells, Lu_SC_H345, CALU6_cells       117040   H89112       yw25e5.s1 Morton Fetal Cochlea  H sapiens     3.16   OVCAR_cells, 293T_cells, EB_cells       129112   N32521   Hs.108738   ESTs   3.16   EB_cells, Fibroblasts 2, MB231_cells       130418   J03242   Hs.251664   insulin-like growth factor 2 (somatomedi   3.16   Caco2, PRSC_con, PRSC_log       131199   R80048   Hs.234433   ESTs; Weakly similar to transporter prot   3.15   PC3_cells, EB_cells, OVCAR_cells       110357   H41529   Hs.33549   ESTs; Highly similar to sulfonylurea rec   3.15   Lu_SQ_H345, PRSC_con, Lu_AD_H23       130068   AA608903   Hs.106220   KIAA0336 gene product   3.15   OVCAR_cells, CALU6_cells, HS578T_cells       127423   T47546   Hs.119252   tumor protein; translationally-controlle   3.15   EB_cells, PRSC_con, LNCaP_cells       105028   AA126719   Hs.25282   ESTs   3.14   LNCaP_cells, PC3_cells, EB_cells       102349   U37547   Hs.75263   apoptosis inhibitor 1   3.14   DU145_cells, HS578T_cells, LNCaP_cells       105126   AA157814   Hs.36288   ESTs   3.13   EB_cells, HS578T_cells, LNCaP_cells       115465   AA286941   Hs.43691   ESTs   3.12   EB_cells, DU145_cells, 293T_cells       133240   AA086452   Hs.68731   triadin   3.12   Lu_SQ_H520, Lu_AD_H23, PRSC_log       122698   AA456112   Hs.99410   ESTs   3.12   DU145_cells, OVCAR_cells, A549_cells       123553   AA608841   Hs.111977   ESTs   3.12   EB_cells, Caco2, DU145_cells       133437   R57419   Hs.7370   ESTs   3.11   HS578T_cells, 293T_cells, Caco2       104956   AA074880   Hs.120975   ESTs; Weakly similar to hypothetical pro   3.11   OVCAR_cells, Fibroblasts 2, Caco2       116314   AA490588   Hs.43118   ESTs   3.11   EB_cells, MB-MDA-435s, HT29_cells       120562   AA280036   Hs.173912   eukaryotic translation initiation factor   3.11   LNCaP_cells, DU145_cells, EB_cells       108770   AA127845   Hs.71027   EST   3.11   Lu_LC_H460, Lu_SC_H345, Lu_AD_358       129791   F02778   Hs.173887   KIAA0876 protein   3.1   Lu_SC_H345, Lu_SC_H69, PRSC_log       115783   AA424487   Hs.72289   ESTs; Weakly similar to LIV-1 protein [H   3.09   Lu_AD_358, EB 13  cells, PC3_cells       107630   AA007218   Hs.60178   ESTs   3.07   Lu_SC_H345, CALU6_cells, Lu_SC_H69       124339   H99093   Hs.6179     H sapiens  mRNA; cDNA DKFZp586K2322 (from   3.07   293T_cells, MB-MDA-453, Caco2       122314   AA442257   Hs.192076   ESTs   3.07   293T_cells, LNCaP_cells, PC3_cells       104589   R79299   Hs.241160   ESTs; Moderately similarto !!!! ALU SUB   3.07   293T_cells, DU145_cells, EB_cells       115687   AA410508   Hs.163765   ESTs; Moderately smlr to ORF derived frm   3.06   Caco2, EB_cells, MB231_cells       123796   AA620390   Hs.247444   ESTs   3.06   Lu_SC_H345, LNCaP_cells, DU145_cells       106483   AA451676   Hs.30299   IGF-II mRNA-binding protein 2   3.06   OVCAR_cells, HMEC (total RNA), HMEC       133318   AA256168   Hs.70838   ESTs   3.05   OVCAR_cells, LNCaP_cells, 293T_cells       117244   N20979   Hs.1757   L1 cell adhesion molecule (hydrocephalus   3.05   MB_cells, MCF7, CALU6_cells                   thumbs) syndrome; spastic paraplegia 1)       130797   AA430050   Hs.180948   KIAA0729 protein   3.05   EB_cells, DU145_cells, DU145_cells       128959   D79791   Hs.107381   ESTs; Weakly similar to F38A5.1 [ C.elega     3.05   LNCaP_cells, HS578T_cells, Lu_SQ_H520       120481   AA252703   Hs.191754   ESTs   3.04   EB_cells, Fibroblasts 2, PRSC_con       126649   AA856990   Hs.125058   ESTs   3.03   OVCAR_cells, LNCaP_cells, 293T_cells       106970   AA504835   Hs.24252   ESTs   3.03   EB_cells, OVCAR_cells, 293T_cells       126488   N34935   Hs.25633   ESts; Highly similar to ARF GTPase-activ   3.03   LU_AD_358, MCF7, MB231_cells       119498   W37226   Hs.55573   ESts   3.01   293T_cells, HS578T_cells, CALU6_cells       129967   H99653   Hs.138618   ESTs   3.01   Lu_SC_H345, Lu_SC_H69, PRSC_log       130698   AA037357   Hs.188212   Ests   3.01   OVCAR_cells, LNCaP_cells, DU145_cells       111018   N54067   Hs.3626   mitogen-activated protein kinase kinase   3.01   PC3_cells, Caco2, Fibroblasts 2       123196   AA489250   Hs.59403   serine palmitoyltransferase; subunit II   3   Lu_SC_H345, BT474_cells, Lu_SC_H69       133229   AA203433   Hs.6834   KIAA1014 protein   3   OVCAR_cells, 293T_cells, EB_cells       130405   H88359   Hs.155396   nuclear factor (erythroid-derived 2)-lik   3   PRSC_con, EB 13  cells, DU145_cells       107881   AA025567   Hs.61273     H sapiens  chromosome 19; cosmid R32611   3   Lu_SQ_H520, MCF7, Lu_AD_358       116589   D59570   Hs.17132   ESTs   3   EB_cells, A549_cells, HS578T_cells       105479   AA255546   Hs.23467   ESTs   2.99   Lu_SC_H345, PC3_cells, OVCAR_cells       115560   AA393812   Hs.50575   ESTs; Moderately similar to !!!! ALU SUB   2.99   EB_cells, Lu_SC_H69, Fibroblasts 2       130166   AA350690   Hs.151411   KIAA0916 protein   2.98   LNCaP_cells, EB_cells, 293T_cells       123355   AA504773   Hs.160557   ESTs   2.98   PRSC_con, PRSC_log, PRSC_log       109546   F01449   Hs.26954   ESTs   2.97   Lu_SC_H345, HT29_cells, BT474_cells       129001   AA448946   Hs.107812   ESTs; Weakly similar to proline-rich pro   2.97   EB_cells, Lu_AD_H23, Lu_AD_358       102259   U28369   Hs.82222   sema domain; immunoglobulin domain (Ig);   2.97   EB_cells, MB231_cells, OVCAR_cells       105583   AA278907   Hs.24549   ESTs   2.96   EB_cells, DU145_cells, 293T_cells       131859   M90657   Hs.3337   transmembrane 4 superfamily member 1   2.96   A549_cells, PC3_cells, DU145_cells       114533   AA053401   Hs.177526   ESTs   2.96   293T_cells, Lu_LC_H460, PC3_cells       110220   H23543   Hs.27090   ESTs   2.95   PRSC_log, Lu_SC_H345, MB231_cells       124917   R91241   Hs.75470   hypothetical protein; expressed in osteo   2.95   Lu_SC_H345, Lu_SC_H69, PRSC_log       127111   AA805726   Hs.220509   ESTs   2.94   HS578T_cells, 293T_cells, 293T_cells       134882   N73762   Hs.90638   ESTs   2.94   EB_cells, MB-MDA-453, Fibroblasts 2       121788   AA423968   Hs.178113   ESTs; Moderately similar to kinesin like   2.94   HT29_cells, CALU6_cells, HMEC       128530   AA504343   Hs.183475     H sapiens  clone 25061 mRNA seq   2.94   DU145_cells, Lu_SC_H345, Caco2       128435   AI301201   Hs.147112   ESTs   2.93   EB_cells, Lu_SQ_H520, PRSC_con       113782   W15580   Hs.15342   phosphate cytidylyltransferase 1; cholin   2.93   EB_cells, Lu_AD_H23, PRSC_log       127569   AA588536   Hs.191783   ESTs   2.93   EB_cells, HS578T_cells, Lu_AD_358       109642   F04465   Hs.22394   ESTs; Weakly similar to weak similarity   2.92   PC3_cells, EB_cells, OVCAR_cells                   protein US)1 [ C.elegans ]       114615   AA083812   Hs.159456   DKFZP566F123 protein   2.92   A549_cells, HS578T_cells, PRSC_con       126808   AA086320       zn52d12.s1 Stratagene muscle 937209  H sa     2.92   Lu_SC_H69, Lu_SC_H345, EB_cells       113947   W84768   Hs.141742   ESTs   2.92   DU145_cells, Fibroblasts 2, MCF7       129455   W27301   Hs.187991   DKFZPS64A122 protein   2.91   OVCAR_cells, DU145_cells, CALU6_cells       107772   AA018587   Hs.40515   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.91   OVCAR_cells, EB_cells, PC3_cells       127159   AA284097   Hs.237955   RAB7; member RAS oncogene family   2.91   293T_cells, OVCAR_cells, PC3_cells       124792   R44357   Hs.132784   ESTs; Weakly similar to cDNA EST EMBL:T0   2.91   DU145_cells, DU145_cells, CALU6_cells       109751   F10210   Hs.6679     H sapiens  mRNA; cDNA DKFZp586A0424 (from   2.91   EB_cells, Lu_SC_H69, 293T_cells       128926   AA481403   Hs.107213   ESTs; Highly similar to NY-REN-6 antigen   2.9   CALU6_cells, EB_cells, OVCAR_cells       106637   AA459961   Hs.250824   ESTs   2.9   EB_cells, Caco2, MB-MDA-435s       132164   U84573   Hs.41270   procollagen-lysine; 2-oxoglutarate 5-dio   2.9   DU145_cells, HS578T_cells, A549_cells       128099   AA905327       ESTs   2.9   MCF7, HMEC (total RNA), 293T_cells       104818   AA034947   Hs.24831   ESTs   2.9   EB_cells, Lu_LC_H460, 293T_cells       126050   H27267   Hs.75860   hydroxyacyl-Coenzyme A dehydrogenase/3-k   2.89   LNCaP_cells, DU145_cells, OVCAR_cells                   -Coenzyme A hydratase (trifunctional pro       116696   F09780   Hs.66124   EST   2.89   CALU6_cells, 293T_cells, 293T_cells       135204   AA421146   Hs.183418   cell division cycle 2-like 1 (PITSLRE pr   2.89   PC3_cells, EB_cells, LNCaP_cells       134946   AA406534   Hs.193053   ESTs; Weakly similar to hiwi [ H.sapiens ]   2.88   EB_cells, LNCaP_cells, Caco2       114975   AA250850   Hs.13944   adrenergic; beta; receptor kinase 2   2.88   EB_cells, EB_cells, EB_cells       113792   W35212   Hs.17691   ESTs; Weakly similar to env protein [H.s   2.88   MB-MDA-435s, Lu_SC_H69, CALU6_cells       102322   U34962   Hs.54473   cardiac-specific homeo box   2.88   293T_cells, HT29_cells, Lu_AD_H23       125642   AI096849   Hs.25274   ESTs; Moderately similar to putative sev   2.88   PC3_cells, CALU6_cells, 293T_cells       100288   D43951   Hs.153834   Human mRNA for KIAA0099 gene; complete c   2.88   293T_cells, LNCaP_cells, EB_cells       105878   AA400184   Hs.24656   KIAA0907 protein   2.88   OVCAR_cells, DU145_cells, 293T_cells       125262   W88755   Hs.108514   ESTs; Highly similar to Trio [ H.sapiens ]   2.88   DU145_cells, HS578T_cells, MB231_cells       114419   AA011448   Hs.106532   ESTs; Weakly similar to transposon LRE2   2.88   EB_cells, Lu_AD_H23, Fibroblasts 2       130639   D59711   Hs.17132   ESTs   2.87   EB_cells, A549_cells, OVCAR_cells       130972   AA370302   Hs.21739     H sapiens  mRNA; cDNA DKFZp586I1518 (from   2.87   293T_cells, A549_cells, Lu_LC_H460       126906   H66949   Hs.168069   ESTs; Highly similar to CALCIUM-BINDING   2.87   Lu_SC_H345, Lu_SC_H69, LNCaP_cells       121807   AA424507   Hs.247478     H sapiens  Mut S homolog 5 gene; partial   2.87   Lu_SC_H69, HT29_cells, RPWE_2                   1C7; LST-1; lymphotoxin beta; tumor necr       105474   AA255440   Hs.219614   F-box protein FBL11   2.87   Lu_AD_H23, Caco2, EB_cells       122348   AA443695   Hs.231476   ESTs   2.87   HT29_cells, Lu_SC_H69, BT474_cells       116368   AA521186   Hs.94217   ESTs   2.86   MB-MDA-453, OVCAR_cells, Lu_SC_H69       135143   AA102644   Hs.69559   KIAA1096 protein   2.86   PC3_cells, EB_cells, 293T_cells       106711   AA464741   Hs.143187   Human DNA from chromosome 19-specific co   2.86   EB_cells, Lu_AD_H23, Lu_LC_H460       128583   L32832   Hs.101842   AT-binding transcription factor 1   2.85   LNCaP_cells, Caco2, EB_cells       132139   AA213410   Hs.111554   ADP-ribosylation factor-like 7   2.85   A549_cells, HS578T_cells, Caco2       114484   AA034378   Hs.252351   HERV-H LTR-associating 2   2.85   PC3_cells, Lu_SQ_H520, MB231_cells       124620   N74051   Hs.194092   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.85   Lu_SC_H345, MB231_cells, Fibroblasts 2       100403   D85527         H sapiens  mRNA for LIM domain, partial c   2.84   Lu_AD_358, Lu_AD_358, MB231_cells       129795   AA448627   Hs.125163   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.84   Lu_SC_H345, OVCAR_cells, PC3_cells       128258   T70214   Hs.183548   ESTs   2.84   DU145_cells, DU145_cells, OVCAR_cells       102662   U70321   Hs.130227   tumor necrosis factor receptor superfami   2.84   EB_cells, Lu_AD_H23, Fibroblasts 2       132232   AA252030   Hs.42640   ESTs   2.84   EB_cells, OVCAR_cells, Lu_SC_H345       106111   AA421638   Hs.6451   ESTs   2.83   EB_cells, Lu_LC_H460, OVCAR_cells       123963   C13961   Hs.210115   EST   2.83   DU145_cells, LNCaP_cells, Lu_SC_H345       122783   AA459895   Hs.98988   ESTs   2.83   EB_cells, MCF7, Lu_SC_H69       112788   R96586   Hs.163630   ESTs   2.82   DU145_cells, Lu_SC_H345, EB_cells       120823   AA347546   Hs.185780   ESTs   2.82   HT29_cells, HMEC (total RNA), BT474_cells       100378   D80009   Hs.10848   KIAA0187 gene product   2.82   Caco2, PC3_cells, OVCAR_cells       114677   AA114163   Hs.188877   ESTs   2.81   DU145_cells, MCF7, EB_cells       108085   AA045602   Hs.62863   ESTs; Moderately similar to senne/threo   2.81   EB_cells, Lu_AD_H23, HT29_cells       104938   AA064627   Hs.18341   ESTs; Highly similar to CGI-72 protein [   2.81   PC3_cells, HS578T_cells, OVCAR_cells       128743   AA237013   Hs.2730   heterogeneous nuclear ribonucleoprotein   2.8   OVCAR_cells, LNCaP_cells, Caco2       124314   H94877   Hs.215766   GTP-binding protein   2.8   LNCaP_cells, DU145_cells, Caco2       134227   D79986   Hs.80338   KIAA0164 gene product   2.8   LNCaP_cells, A549_cells, EB_cells       122922   AA476268       zw44h1.s1 Soares_total_fetus_Nb2HF8_9w H   2.79   Lu_SC_H345, OVCAR_cells, Lu_SC_H69                   contains Alu repetitive element; contain       128096   H42968   Hs.155606   paired mesoderm homeo box 1   2.78   Lu_AD_H23, Lu_SC_H69, Lu_LC_H460       129295   AA424782   Hs.110121   SEC7 homolog   2.78   Lu_AD_H23, EB_cells, Lu_SC_H345       116155   AA460957   Hs.76053   DEAD/H (Asp-Glu-Ala-Asp/His) box polypep   2.78   EB_cells, OVCAR_cells, 293T_cells       105911   AA401809   Hs.189910   ESTs   2.77   293T_cells, HS578T_cells, DU145_cells       119232   T03475   Hs.258624   EST   2.77   EB_cells, Lu_AD_H23, Lu_AD_358       131168   AA482007   Hs.23788   ESTs; Weakly similar to homology with is   2.77   EB_cells, Lu_LC_H460, MCF7       106048   AA416697   Hs.15330   ESTs   2.76   OVCAR_cells, Lu_SC_H345, 293T_cells       124352   N21626   Hs.102406   ESTs   2.76   MCF7, MB-MDA-453, CALU6_cells       129349   D86974   Hs.110613   KIAA0220 protein   2.76   DU145_cells, HT29_cells, Lu_SC_H69       106120   AA423808   Hs.8765   RNA helicase-related protein   2.76   OVCAR_cells, EB_cells, 293T_cells       100643   HG2755-H       T-Plastin   2.75   293T_cells, PC3_cells, HS578T_cells       128500   U60521   Hs.100641   caspase 9; apoptosis-releted cysteine pr   2.75   Lu_AD_358, Lu_SC_H69, Lu_SC_H345       126090   R44789   Hs.119486   ESTs; Weakly similar to rostral cerebell   2.75   Lu_SC_H69, Lu_SC_H345, BT474_cells       127064   Z43709       HSC1JA091 normalized infant brain cDNA H   2.75   Caco2, A549_cells, HT29_cells       132989   AA480074   Hs.394   adrenomedullin   2.75   EB_cells, OVCAR_cells, DU145_cells       108888   AA135606   Hs.189384   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.75   OVCAR_cells, LNCaP_cells, DU145_cells       119579   W42429   Hs.150607   ESTs   2.74   293T_cells, DU145_cells, PC3_cells       100387   D83777   Hs.75137   KIAA0193 gene product   2.74   CALU6_cells, DU145_cells, Caco2       114744   AA135407   Hs.252351   HERV-H LTR-associating 2   2.74   PC3_cells, Lu_SQ_H520, RPWE_2       129092   AA011243   Hs.63525   poly(rC)-binding protein 2   2.74   EB_cells, MCF7, DU145_cells       125360   AA677978   Hs.189741   ESTs   2.74   Lu_AD_358, Lu_AD_358, PRSC_log       107874   AA025305   Hs.25218   ESTs; Weakly similar to reverse transcti   2.74   Lu_SC_H345, Lu_LC_H460, HT29_cells       114086   Z38266   Hs.12770     H sapiens  PAC done DJ0777O23 from 7p14-   2.74   EB_cells, LNCaP_cells, BT474_cells       116180   AA463902   Hs.94964   ESTs   2.73   Lu_SC_H69, PRSC_con, Lu_AD_H23       126027   M61982       ESTs   2.73   LNCaP_cells, DU145_cells, A549_cells       116339   AA496257   Hs.72165   ESTs; Weakly similar to R26984_1 [ H.sapi     2.73   EB_cells, DU145_cells, OVCAR_cells       105387   AA236951   Hs.108636   chromosome 1 open reading frame 9   2.72   PC3_cells, EB_cells, Caco2       111359   N91273   Hs.27179   ESTs   2.72   EB_cells, LNCaP_cells, 293T_cells       106680   AA461458   Hs.24789   ESTs   2.72   PC3_cells, Lu_SC_H345, Caco2       118598   N69136   Hs.214343   ESTs   2.72   MB-MDA-453, 293T_cells, BT474_cells       107913   AA027161   Hs.59523   ESTs; Highly similar to G1 TO S PHASE TR   2.71   EB_cells, MCF7, Lu_SC_H345       134315   AA136269   Hs.81648   ESTs; Weakly similar to S164 [ H.sapiens ]   2.71   EB_cells, DU145_cells, HMEC       135233   AA127463   Hs.9683   protein-kinase; interferon-inducible dou   2.71   EB 13  cells, OVCAR_cells, Caco2       112932   T15470   Hs.189810   ESTs   2.7   293T_cells, Lu_AD_H23, PC3_cells       119053   R11501       yf28f1.s1 Soares fetal liver spleen 1NFL   2.7   Lu_SC_H345, Lu_SC_H69, DU145_cells                   contains Alu repetitive element; mRNA       131206   AA044078   Hs.24210   ESTs   2.7   Caco2, Lu_SC_H345, HS578T_cells       126759   AA063642       ESTs; Highly similar to (defline not ava   2.7   LNCaP_cells, Lu_SC_H345, LuSC_H69       131060   AA160890   Hs.22564   myosin VI   2.7   LNCaP_cells, MCF7, HT29_cells       132135   N69101   Hs.40730   ESTs   2.7   EB_cells, 293T_cells, OVCAR_cells       120835   AA348446   Hs.96906   ESTs   2.7   Fibroblasts 2, CALU6_cells, RPWE_2       113815   W45311   Hs.14756   ESTs   2.7   EB_cells, PC3_cells, DU145_cells       133234   T90092   Hs.6853   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.69   Lu_SC_H345, OVCAR_cells, DU145_cells       126819   AA305536   Hs.161489   ESTs   2.69   EB_cells, DU145_cells, Caco2       125198   W69474   Hs.225550   ESTs   2.69   Lu_SC_H345, Lu_AD_H23, Lu_AD_H23       108394   AA075144       zm86f6.s1 Stratagene ovarian cancer (#93   2.69   HMEC, HMEC (total RNA), Fibroblasts 2                   gb:X1664 TRANSLATIONALLY CONTROLLED TUM       134456   X59405   Hs.83532   membrane cofactor protein (CD46; trophob   2.69   EB_cells, LNCaP_cells, DU145_cells       111720   R23739   Hs.23585   KIAA1078 protein   2.88   PC3_cells, HMEC (total RNA), OVCAR_cells       114617   AA084148   Hs.110659   ESTs   2.68   DU145_cells, LNCaP_cells, OVCAR_cells       127787   AA731764       ESTs; Weakly similar to !!!! ALU CLASS C   2.68   HT29_cells, Lu_SC_H345, MB231_cells       101437   M20681   Hs.7594   solute carrier family 2 (facilitated glu   2.68   Caco2, Lu_LC_H460, Fibroblasts 2       133761   AA477223   Hs.75922   brain protein I3   2.68   EB_cells, Lu_AD_H23, Lu_SC_H345       105869   AA399574   Hs.19086   ESTs   2.68   PC3_cells, MCF7, MB231_cells       125191   W67257   Hs.138871   ESTs; Weakly similar to !!!! ALU CLASS B   2.88   OVCAR_cells, DU145_cells, LNCaP_cells       116238   AA479352   Hs.47144   DKFZP586N0819 protein   2.67   OVCAR_cells, DU145_cells, LNCaP_cells       124770   R40555   Hs.120429   ESTs   2.67   Lu_AD_H23, Lu_SC_H69, PRSC_con       101764   M80563   Hs.81256   S100 calcium-binding protein A4 (calcium   2.67   A549_cells, MB231_cells, OVCAR_cells                   murine placental homolog)       130897   AA063428   Hs.21022   adaptor-related protein complex 3; beta   2.67   EB_cells, Lu_AD_H23, HMEC       133303   H61048   Hs.237352   EST   2.66   Lu_SC_H345, Lu_SC_H69, PRSC_con       124724   R12405   Hs.112423     H sapiens  mRNA; cDNA DKFZpS86I1420 (from   2.66   Lu_SC_H345, BT474_cells, OVCAR_cells       123697   AA609601   Hs.221224   ESTs   2.66   OVCAR_cells, 293T_cells, Lu_SC_H69       111548   R09170   Hs.258707   ESTs   2.66   293T_cells, CALU6_cells, A549_cells       107005   AA598679   Hs.194215   ESTs   2.66   Lu_SC_H345, OVCAR_cells, Lu_AD_H23       105569   AA278399   Hs.20596   ESTs   2.65   MCF7, HT29_cells, BT474_cells       132687   AB002301   Hs.54985   KIAA0303 protein   2.65   HMEC (total RNA), HMEC, LNCaP_cells       104105   AA422123   Hs.42457   ESTs   2.65   Lu_SC_H345, Lu_SC_H69, DU145_cells       121335   AA404418   Hs.144953   ESTs   2.65   EB_cells, Fibroblasts 2, DU145_cells       124853   R61693   Hs.172330   ESTs; Weakly similar to Wiskott-Aldrich   2.64   Lu_SC_H69, 293T_cells, EB_cells       124253   H69742   Hs.102201   ESTs   2.64   DU145_cells, OVCAR_cells, Lu_SC_H345       123044   AA481549   Hs.165694   ESTs   2.64   EB_cells, Lu_SC_H69, Lu_SC_H345       129535   AA608852   Hs.112603   EST   2.64   EB_cells, Lu_AD_H23, Fibroblasts 2       131397   AB002336   Hs.26395   erythrocyte membrane protein band 4.1-li   2.64   EB_cells, DU145_cells, Caco2       130175   X75593   Hs.151536   RAB13; member RAS oncogene family   2.64   Fibroblasts 2, PRSC_con, HS578T_cells       127507   AI188445   Hs.152618   ESTs   2.63   EB_cells, Lu_AD_H23, Lu_LC_H460       105377   AA236702   Hs.24371   ESTs   2.63   Caco2, EB 13  cells, CALU6_cells       114671   AA112679   Hs.252291   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.63   EB_cells, DU145_cells, Caco2       133726   W19983   Hs.75761   SFRS protein kinase 1   2.63   EB_cells, Lu_AD_H23, Lu_SC_H69       132380   H68018       yr76h05.r1 Soares fetal liver spleen 1NF   2.62   EB 13  cells, Lu_AD_H23, Lu_SC_H69                   IMAGE:211257 5′, mRNA seq.       127986   AI370418   Hs.192050   ESTs; Weakly similar to !!!! ALU CLASS A   2.62   DU145_cells, OVCAR_cells, LNCaP_cells       116208   AA476333   Hs.42532   ESTs   2.61   DU145_cells, PRSC_con, Fibroblasts 2       130946   AA069456   Hs.21490   KIAA0438 gene product   2.6   LNCaP_cells, DU145_cells, HS578T_cells       106687   AA463234   Hs.119387   KIAA0792 gene product   2.59   EB 13  cells, MB-MDA-453, Caco2       101551   M31606   Hs.196177   phosphorylase kinase; gamma 2 (testis)   2.59   LNCaP_cells, EB_cells, MB-MDA-453       114479   AA032084   Hs.124841   ESTs; Moderately similar to transformati   2.59   DU145_cells, Caco2, OVCAR_cells       111863   R37495   Hs.23578   ESTs   2.59   HT29_cells, MB231_cells, Lu_SQ_H520       129018   AA029973   Hs.107979   small membrane protein 1   2.59   A549_cells, EB_cells, HS578T_cells       107058   AA600357   Hs.239409   TIA1 cytotoxic granule-associated RNA-bi   2.58   DU145_cells, Lu_SC_H345, EB_cells       126175   AA056181   Hs.17311   DKFZP434N161 protein   2.58   Lu_SC_H345, DU145_cells, LNCaP_cells       131979   D52154   Hs.172458   iduronate 2-sulfatase (Hunter syndrome)   2.58   DU145_cells, PC3_cells, A549_cells       126122   H80181       ESTs   2.58   DU145_cells, OVCAR_cells, LNCaP_cells       106961   AA504110   Hs.18063   ESTs   2.58   HMEC, DU145_cells, DU145_cells       114730   AA133527   Hs.126925   ESTs; Weakly similar to The K1AA0138 gen   2.58   DU145_cells, LNCaP_cells, MCF7       117342   N24020   Hs.132913   ESTs   2.58   HS578T_cells, DU145_cells, LNCaP_cells       131622   AA424813   Hs.29692   ESTs   2.57   PRSC_con, PRSC_log, HS578T_cells       104904   AA055560   Hs.13179   ESTs; Moderately similar to !!!! ALU SUB   2.57   Lu_SC_H345, Lu_SC_H69, BT474_cells       117359   N24848   Hs.114062   ESTs; Weakly similar to T15B7.2 [ C.elega     2.57   HS578T_cells, PRSC_con, EB_cells       123331   AA497013   Hs.188740   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.57   Lu_SC_H69, Caco2, PRSC_con       125324   R07785       yf15c06.r1 Soares fetal liver spleen 1NF   2.57   EB_cells, Lu_AD_H23, Fibroblasts 2                   contains Alu repetitive element; contain       129813   T33462   Hs.12600   ESTs   2.57   Lu_SC_H345, 293T_cells, Lu_SC_H69       100265   D38521   Hs.75935   KIAA0077 protein   2.57   EB_cells, LNCaP_cells, PC3_cells       134890   T40902   Hs.90786   ATP-binding cassette; sub-family C (CFTR   2.57   A549_cells, DU145_cells, EB_cells       133582   AA421874   Hs.75087   Fas-activated serine/threonine kinase   2.56   EB_cells, Lu_AD_H123, Lu_AD_358       135011   H73161   Hs.92991   ESTs; Weakly similar to C13F10.4 [ C.eleg     2.56   EB_cells, LNCaP_cells, MB-MDA-453       107226   D58185   Hs.21945   ESTs   2.56   Lu_SC_H345, Lu_SC_H69, HMEC (total RNA)       126042   H62441   Hs.157082     H sapiens PAC  clone DJ0988G15 from 7q33-   2.56   HMEC (total RNA), HMEC, RPWE_2       114472   AA028924   Hs.177407   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.56   Lu_SC_H345, Lu_SC_H69, DU145_cells       126291   N42090       yy05b07.r1 Soares melanocyte 2NbHM  H sap     2.56   HMEC, HMEC (total RNA), PC3_cells       113349   T79021   Hs.14438   ESTs; Moderately similar to histamine N-   2.56   HT29_cells, PRSC_log, Lu_SC_H345       105789   AA347485   Hs.25477   ESTs; Moderately similar to rig-1 protel   2.56   Lu_AD_H23, RPWE_2, Lu_SQ_H520       110918   N46423   Hs.24283   ESTs   2.56   EB_cells, CALU6_cells, DU145_cells       117170   H98153   Hs.42500   ADP-ribosylation factor-like 5   2.56   OVCAR_cells, EB_cells, LNCaP_cells       105159   AA173981   Hs.30490   CD2-associated protein   2.55   LNCaP_cells, EB_cells, DU145_cells       105726   AA292328   Hs.9754   activating transcription factor 5   2.55   MCF7, EB_cells, MB-MDA-453       132079   H67964   Hs.38694   ESTs   2.55   EB_cells, DU145_cells, HS578T_cells       131813   X51757   Hs.3268   heat shock 70 kD protein 6 (HSP70B′)   2.55   Lu_AD_H23, MB231_cells, Fibroblasts 2       133538   L14837   Hs.74614   tight junction protein 1 (zona occludens   2.54   DU145_cells, Caco2, A549_cells       124981   T40849   Hs.114034   maternal G10 transcript   2.54   EB_cells, Caco2, LNCaP_cells       122028   AA431306   Hs.98722   ESTs   2.54   Fibroblasts 2, BT474_cells, HMEC (total RNA)       122487   AA448332   Hs.80598   transcription elongation factor A (SII);   2.54   Lu_SC_H345, MCF7, MB-MDA-453       119315   T41152   Hs.90485   ESTs   2.54   Lu_SC_H345, MB-MDA-435s, PRSC_con       107957   AA031948   Hs.57548   ESTs   2.54   A549_cells, RPWE_2, DU145_cells       122457   AA447780   Hs.96418   ESTs   2.54   DU145_cells, EB_cells, A549_cells       103572   Z25749   Hs.75538   ribosomal protein S7   2.54   EB_cells, CALU6_cells, DU145_cells       124395   N29963   Hs.193977   ESTs   2.54   HMEC (total RNA), HMEC, RPWE_2       116024   AA451748   Hs.83883   Human DNA seq from clone 718J7 on chromo   2.53   LNCaP_cells, RPWE_2, MB-MDA-453                   phosphoenolpyruvate carboxykinase 1; ES       134361   D43682   Hs.82208   acyl-Coenzyme A dehydrogenase; very long   2.63   LNCaP_cells, CALU6_cells, DU145_cells       130420   U60975       Human hybrid receptor gp25 precursor mRN   2.53   EB_cells, HMEC (total RNA), Caco2       100336   D63478   Hs.8127   KIAA0144 gene product   2.53   BT474_cells, HT29_cells, Lu_AD_358       105519   AA258063   Hs.23438   ESTs   2.53   EB_cells, Caco2, MB-MDA-435s       124684   R02401   Hs.221078   ESTs   2.53   Lu_SC_H345, OVCAR_cells, Lu_SC_H69       105852   AA398933   Hs.172613   solute carrier family 12 (potassium/chlo   2.52   LNCaP_cells, DU145_cells, EB_cells       105012   AA116036   Hs.9329   chromosome 20 open reading frame 1   2.52   CALU6_cells, Caco2, DU145_cells       126534   W39128   Hs.247901   Human DNA seq from clone 8B1 on chromoso   2.52   BT474_cells, LNCaP_cells, Lu_AD_H23                   -CELL MEMBRANE GLYCOPROTEIN PC-1; the ge       135334   AA053134   Hs.241558   ariadne-2 (D. melanogaster) homolog (all   2.52   293T_cells, CALU6_cells, DU145_cells       128538   R44214   Hs.101189   ESTs   2.52   EB_cells, Lu_AD_H23, Lu_SC_H345       109865   H02566   Hs.191268     H sapiens  mRNA; cDNA DKFZp434N174 (from   2.52   DU145_cells, LNCaP_cells, OVCAR_cells       118579   N68905       small inducible cytokine A5 (RANTES)   2.51   Lu_SC_H345, LNCaP_cells, Lu_SC_H69       117590   N34904       ESTs; Moderately similarto !!!! ALU SUB   2.51   Lu_SC_H345, DU145_cells, Lu_SC_H69       104340   F15201       ESTs   2.51   Lu_SC_H345, PRSC_con, PRSC_log       122455   AA447744   Hs.99141   EST   2.51   Caco2, Lu_SC_H69, 293T_cells       109339   AA211901   Hs.86430   ESTs   2.51   EB_cells, DU145_cells, CALU6_cells       123258   AA490929   Hs.105274   ESTs   2.51   EB_cells, Lu_AD_H23, Lu_SC_H69       118467   N66763   Hs.43080   ESTs   2.51   CALU6_cells, HS578T_cells, OVCAR_cells       106044   AA416548   Hs.149436   kinesin family member 5B   2.51   EB_cells, Caco2, DU145_cells       107480   W58057   Hs.74304   periplakin   2.5   Caco2, OVCAR_ceUs, HMEC (total RNA)       111760   R26892   Hs.221434   ESTs   2.5   Lu_AD_H23, EB_cells, Lu_AD_358       132474   N68018   Hs.180930   TBP-associated factor 172   2.5   LNCaP_cells, EB_cells, DU145_cells       103423   X97249   Hs.123122   FSH primary response (LRPR1; rat) homolo   2.5   HS578T_cells, Lu_SC_H345, PC3_cells       123488   AA599708   Hs.187764   ESTs; Weakly similar to !!!! ALU SUBEAMI   2.49   OVCAR_cells, Lu_SC_H345, DU145_cells       100475   D90276   Hs.12   carcincembryonic antigen-related cell ad   2.49   MB-MDA-453, 293T_cells, CALU6_cells       112003   R42547   Hs.172551   ESTs   2.49   EB_cells, Lu_AD_H23, Lu_SC_H345       114315   Z41027   Hs.26297   ESTs   2.49   Lu_SC_H69, OVCAR_cells, Lu_AD_H23       105291   AA233311   Hs.28752   ESTs   2.49   EB_cells, CALU6_cells, DU145_cells       135354   AA188934   Hs.99367   ESTs   2.49   MB-MDA-453, Lu_SC_H69, 293T_cells       107521   X78262         H.sapiens  mRNA for TRE5   2.49   Lu_SC_H345, Lu_SC_H69, PRSC_con       108373   AA074393   Hs.61950   ESTs: Weakly similar to nuclear protein   2.49   MCF7, MB-MDA-453, Lu_SC_H345       108836   AA132061   Hs.222727   ESTs; Weakly similar to ubiquitous TPR m   2.48   DU145_cells, Lu_SC_H345, Lu_SC_H345       110386   H45516   Hs.33268   ESTs   2.48   PC3_cells, OVCAR_cells, Lu_SQ_Y520       129658   M22348   Hs.131255   ubiquinol-cytochrome c reductase binding   2.48   LNCaP_cells, CALU6_cells, PC3_cells       134283   H12661   Hs.8107     H sapiens  mRNA; cDNA DKFZpS86B0918 (from   2.48   HMEC (total RNA), HS578T_cells, HMEC       101844   M93425   Hs.62   protein tyrosine phosphatase; non-recept   2.48   DU145_cells, EB_cells, CALU6_cells       133461   M33318   Hs.183584   cytochrome P450; subfamily IIA (phenobar   2.48   EB_cells, Lu_AD_H23, Lu_AD_358       103545   Z14000   Hs.35384   ring finger protein 1   2.47   HT29_cells, Lu_SQ_H520, BT474_cells       128440   N76763       ESTs   2.47   EB_cells, Lu_AD_H23, Lu_AD_358       134992   H05625   Hs.92414   ESTs   2.47   Lu_SC_H345, CALU6_cells, Lu_SC_H69       116295   AA489016   Hs.91216   ESTs; Highly similar to partial CDS; hum   2.47   MB-MDA-453, 293T_cells, MB-MDA-435s       107004   AA598675   Hs.239475   ESTs   2.47   LNCaP_cells, Cace2, OVCAR_cells       132137   AA282312   Hs.4076   CTD (carboxy-terminal domain; RNA polyme   2.46   Lu_SC_H69, HMEC, EB_cells       126390   W28286   Hs.100090   tetraspan 3   2.46   EB_cells, DU145_cells, LNCaP_cells       113050   T26366   Hs.22711   EST; Weakly similar to 60S RIBOSOMAL PRO   2.46   Lu_LC_H460, EB_cells, Lu_AD_358       101667   M60858   Hs.79110   nucleolin   2.46   PC3_cells, 293T_cells, A549_cells       108569   AA085398       zn7e3.s1 Stratagene hNT neuron (#937233)   2.45   HT29_cells, BT474_cells, Lu_SQ_H520                   IMAGE:546748 3′, mRNA seq       117186   H98988   Hs.42612   ESTs   2.45   EB_cells, Lu_AD_H23, Lu_AD_358       129091   AA044622   Hs.183755   Human Chromosome 16 BAG clone CIT987SK-A   2.45   EB_cells, Lu_AD_H23, Lu_AD_H23       128468   T23625   Hs.258674   EST   2.45   Lu_AD_H23, EB_cells, Lu_SC_H69       117498   N31726   Hs.44268   ESTs; Highly similar to myelin gene expr   2.45   Lu_SC_H69, DU145_cells, OVCAR_cells       105407   AA243478   Hs.5206   ESTs   2.45   EB_cells, 293T_cells, PC3_cells       128941   R55763   Hs.107287   ESTs   2.44   EB_cells, LNCaP_cehls, A549_cells       116486   C14128   Hs.251980   EST   2.44   MB-MDA-435s, HS578T_cells, 293T_cells       134869   T35288   Hs.90421   ESTs; Moderately similar to !!!! ALU SUB   2.44   EB_cells, Lu_AD_H23, Lu_AD_358       130664   R09049   Hs.17625   ESTs   2.44   PC3_cells, EB_cells, A549_cells       107985   AA035638   Hs.71968     H sapiens  mRNA; cDNA DKFZpS54F053 (from   2.44   PRSC_con, PRSC_log, Caco2       110300   H37820   Hs.124147   ESTs   2.44   MB-MDA-453, Caco2, OVCAR_cells       113471   T87174   Hs.16341   ESTs; Moderately similar to !!!! ALU SUB   2.44   Caco2, OVCAR_cells, LNCaP_cells       131474   U28749   Hs.2726   high-mobility group (nonhistone chromoso   2.44   CALU6_cells, OVCAR_cells, 293T_cells       120791   AA342802   Hs.194031   ESTs   2.44   Lu_AD_H23, Lu_SQ_H520, PRSC_con       133733   AA416973   Hs.75798   Human DNA seq from clone 1183I21 on chro   2.43   EB_cells, Caco2, DU145_cells                   to predicted fly and worm proteins. Con       119977   W88579   Hs.124744   ESTs   2.43   HT_cells, HMEC (total RNA), HMEC       134921   W60186   Hs.169487   Kreisler (mouse) maf-related leucine zip   2.43   LNCaP_cells, HS578T_cells, MB-MDA-453       132295   H66351   Hs.181042   Dmx-hike 1   2.43   Lu_SC_H69, BT474_cells, Lu_SQ_H520       133395   AA491296   Hs.72805   ESTs   2.43   EB_cells, LNCaP_cells, OVCAR_cells       106728   AA465355   Hs.153768   U3 snoRNP-associated 55-kDa protein   2.43   EB_cells, Lu_AD_H23, PC3_cells       116370   AA521256   Hs.236204   ESTs; Moderately similar to NUCLEAR PORE   2.43   EB_cells, A549_cells, 293T_cells       113936   W81552   Hs.83623   nuclear receptor subfamily 1; group I; m   2.43   293T_cells, OVCAR_cells, Fibroblasts 2       128862   R61297   Hs.106673   eukaryotic translation initiation factor   2.43   EB_cells, DU145_cells, DU145_cells       111614   R12581   Hs.191146   ESTs   2.43   HMEC (total RNA), Fibroblasts 2, MB-MDA-435s       111993   R42241   Hs.106359   ESTs   2.43   A549_cells, DU145_cells, CALU6_cells       131554   AA100026   Hs.28669   ESTs; Weakly similar to PROTEIN-TYROSINE   2.43   EB_cells, LNCaP_cells, Caco2       130983   N71215   Hs.21862   NCK-associated protein 1   2.42   EB_cells, Caco2, A549_cells       131654   AA497050   Hs.30204   ESTs   2.42   MCF7, MB-MDA-435s, Lu_SC_H345       105014   AA121123   Hs.191374   ESTs   2.42   EB_cells, Lu_AD_H23, Lu_LC_H460       106300   AA435840   Hs.19114   high-mobility group (nonhistone chromoso   2.42   EB_cells, LuSC_H345, A549_cells       102386   U40998   Hs.81728   unc119 (C.elegans) homolog   2.42   OVCAR_cells, EB_cells, DU145_cells       112517   R68589   Hs.23721   ESTs   2.42   Caco2, MCF7, DU145_cells       125375   H72971       KIAA0277 gene product   2.42   Lu_SC_H345, OVCAR_cells, Lu_SC_H69       123808   AA620552   Hs.25682   ESTs; Weakly similar to PHOSPHATIDYLETHA   2.42   EB_cells, Lu_AD_H23, Lu_SC_H69       114950   AA243503   Hs.11801   adenosine A2b receptor pseudogene   2.42   MB-MDA-453, HT29_cells, Lu_LC_H460       129906   H39216   Hs.239970   ESTs; Weakly similar to ZNF91L [ H.sapien     2.41   Lu_SC_H345, Fibroblasts 2, DU145_cells       103408   X95876   Hs.198252   G protein-coupled receptor 9   2.41   RPWE_2, PRSC_log, Lu_SC_H345       129703   AA401348   Hs.179999   ESTs   2.41   EB_cells, 293T_cells, DU145_cells       105693   AA287104   Hs.181368   U5 snRNP-speciflc protein (220 kD); orth   2.41   293T_cells, CALU6_cells, A549_cells       106532   AA453628   Hs.37443   ESTs   2.41   ES_cells, OVCAR_cells, Caco2       132132   AA010933   Hs.4055   core promoter element binding protein   2.41   HMEC, HMEC (total RNA), EB_cells       111409   R00311   Hs.18798   EST; Weakly similar to !!!! ALU SUBFAMIL   2.41   Lu_SC_H345, Lu_SC_H69, PRSC_con       133813   M26657   Hs.250711   dipeptidyl carboxypeptidase 1 (angiotens   2.41   HT29_cells, BT474_cells, MB231_cells       127240   AA888387   Hs.243845   ESTs; Moderately similar to !!!! ALU SUB   2.41   Lu_SC_H345, DU145_cells, LNCaP_cells       104975   AA086071   Hs.50758   chromosome-associated polypeptide C   2.41   OVCAR_cells, DU145_cells, PC3_cells       118078   N54321   Hs.47790   EST   2.41   EB_cells, Fibroblasts 2, HMEC (total RNA)       115840   AA429253   Hs.58103   A kinase (PRKA) anchor protein 9   2.41   OVCAR_cells, EB_cells, PC3_cells       101186   L20298   Hs.179881   core-binding factor; beta subunit   2.4   EB_cells, DU145_cells, CALU6_cells       113098   T40936   Hs.8349   ESTs   2.4   Caco2, HT_cells, EB_cells       115185   AA259140   Hs.60238   ESTs   2.4   Lu_SC_H69, EB_cells, Caco2       113778   W15263   Hs.5422   ESTs   2.4   Caco2, MB-MDA-435s, LNCaP_cells       128261   AI061213   Hs.13179   ESTs; Moderately similar to !!!! ALU SUB   2.4   DU145_cells, LNCaP_cells, OVCAR_cells       132210   AA235013   Hs.42322   A kinase (PRKA) anchor protein 2   2.4   Caco2, DU145_cells, PRSC_log       112561   R72427   Hs.129873   ESTs; Weakly similar to CYTOCHROME P450   2.4   Lu_SQ_H520, Lu_AD_H23, EB_cells       127598   AA610677   Hs.168851   ESTs   2.4   LNCaP_cells, DU145_cells, OVCAR_cells       106664   AA460969   Hs.7510   mitogen-activated protein kinase kinase   2.4   OVCAR_cells, 293T_cells, A549_cells       131367   AA456687   Hs.26057   ESTs   2.4   EB_cells, MB-MDA-453, 293T_cells       103163   X67683         H.sapiens  mRNA for keratin 4   2.39   EB_cells, LuAD_H23, Lu_AD_358       109639   F04444   Hs.6217   ESTs; Weakly similar to !!!! ALU SUSFAMI   2.39   EB_cells, Lu_SC_H345, Lu_SC_H69       112007   R42671   Hs.140853   EST; Weakly similar to !!!! ALU SUBFAMIL   2.39   MB-MDA-435s, Lu_SC_H345, Lu_AD_H23       100023           AFFX control: BioC-3   2.39   Caco2, Lu_AD_358, LNCaP_cells       119923   W86214   Hs.184642   ESTs   2.39   EB_cells, HS578T_cells, DU145_cells       127705   AJ003307       AJ003307 Selected dir 21 cDNA library H   2.39   Lu_AD_H23, Lu_SC_H345, Lu_LC_H460       130362   AA182658   Hs.179817   DKFZP586F0222 protein   2.39   EB_cells, DU145_cells, PC3_cells       100168   D14874   Hs.394   adrenomedullin   2.39   Fibroblasts 2, Caco2, HS578T_cells       134261   AA227678   Hs.8084   Human DNA seq from clone 465N24 on chr 1   2.39   PRSC_con, MB-MDA-453, LNCaP_cells                   Contains two novel genes; ESTs; GSSs an       103392   X94563         H.sapiens  dbi/acbp gene exon 1 &amp; 2   2.38   ES_cells, Lu_AD_H23, Lu_SC_H69       129888   U81001   Hs.131891   Human SNRPN mRNA; 3′ UTR; partial seq   2.38   LNCaP_cells, Lu_SC_H69, Lu_LC_H460       130119   T12649   Hs.251653   tubulin; beta; 2   2.38   Lu_AD_H23, Lu_LC_H460, Lu_LC_H460       118136   N57710   Hs.233952   proteasome (prosome; macropain) subunit   2.38   293T_cells, OVCAR_cells, HS578T_cells       131163   H80107   Hs.23754   ESTs   2.38   Lu_AD_H23, Lu_SC_H69, Lu_SC_H345       115964   AA448622   Hs.74313   ESTs   2.38   EB_cells, LNCaP_cells, DU145_cells       135026   H59730   Hs.93231   ESTs   2.37   EB_cells, 293T_cells, Lu_SC_H69       133300   D51401   Hs.70333   ESTs   2.37   OVCAR_cells, Caco2, CALU6_cells       129948   H69281   Hs.13643   ESTs   2.37   EB_cells, Lu_AD_H23, Lu_SC_H345       112505   R67923   Hs.23368   ESTs   2.37   DU145_cells, OVCAR_cells, 293T_cells       130715   T98227   Hs.171952   occludin   2.37   Caco2, LNCaP_cells, DU145_cells       120301   AA192163   Hs.104085   EST   2.37   Lu_AD_H23, EB_cells, PRSC_con       128062   AA379500   Hs.193155   ESTs   2.37   EB_cells, LNCaP_cells, DU145_cells       127154   AA789101   Hs.198860   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.37   HS578T_cells, MCF7, Lu_SC_H69       102814   U90716   Hs.79187   coxsackie virus and adenovirus receptor   2.37   OVCAR_cells, DU145_cells, Lu_SC_H345       120239   Z41691   Hs.65919   ESTs   2.37   EB 13  cells, DU145_cells, LNCaP_cells       106829   AA481883   Hs.31236   ESTs; Weakly similar to Unknown [ H.sapie     2.37   EB_cells, DU145_cells, OVCAR_cells       132681   AA435762   Hs.54894   ESTs; Highly similar to unknown [ H.sapie     2.37   EB_cells, LNCaP_Cells, PRSC_con       108845   AA132946   Hs.68864   ESTs   2.36   Lu_AD_H23, Lu_AD_358, Lu_SQ_H520       133226   T85327   Hs.169552   ESTs   2.36   Caco2, MB-MDA-453, MCF7       106789   AA478726   Hs.26373   ESTs; Moderately similar to !!!! ALU SUB   2.36   MS-MDA-453, Caco2, OVCAR_cells       119236   T10166   Hs.237297   ESTs   2.36   EB_cells, 293T_cells, LNCaP_cells       106619   AA459255   Hs.23956   ESTs   2.36   LNCaP_cells, A549_cells, Caco2       109178   AA181600   Hs.62741   ESTs   2.36   Lu_SC_H345, LNCaP_cells, EB_cells       112724   R91753   Hs.17757   ESTs   2.36   Caco2, EB_cells, DU145_cells       112655   R85069   Hs.141139   ESTs   2.36   Fibroblasts 2, Lu_AD_H23, Lu_LC_H460       132820   AA454988   Hs.57621   ESTs   2.36   EB_cells, OVCAR_cells, HS578T_cells       106155   AA425309   Hs.33287   nuclear factor I/B   2.36   OVCAR_cells, Lu_SC_H345, MB-MDS-453       114632   AA084742   Hs.194380   ESTs; Weakly similar to !!!! ALU SUSFAMI   2.35   Lu_SC_H345, Lu_LC_H460, Lu_AD_H23       134776   J05582   Hs.89603   mucin 1; transmembrane   2.35   DU145_cells, Lu_AD_H23, Lu_AD_358       101192   L20859   Hs.78452   solute carrier family 20 (phosphate tran   2.35   PC3_cells, CALU6_cells, MS-MDA-435s       130349   W16686   Hs.171825   basic helix-loop-helix domain containing   2.35   A649_cells, DU145_cells, HT29_cells       106389   AA448949   Hs.6236   ESTs   2.36   LNCaP_cells, PC3_cells, DU145_cells       109637   F04426   Hs.23131   kinesin family member C3   2.35   MB-MDA-435s, A549_cells, Lu_LC_H460       101483   M24486   Hs.76768   procollagen-proline; 2-oxoglutarate 4-di   2.35   PC3_cells, HS578T_cells, EB_cells       131751   H18335   Hs.31562   ESTs   2.35   DU145_cells, MB231_cells, HMEC       131050   X13967   Hs.2250   leukemia inhibitory factor (cholinergic   2.35   Lu_AD_H23, PC3_cells, PRSC_log       130097   N21159   Hs.14845   forkhead box O3A   2.34   EB_cells, LNCaP_cells, LNCaP_cells       134533   AA013468   Hs.241493   natural killer-tumor recognition seq   2.34   EB_cells, HT29_cells, HMEC       134839   D63479   Hs.115907   diacylglycerol kinase; delta (130 kD)   2.34   Lu_LC_H460, Caco2, DU145_cells       115690   AA410894   Hs.44159   ESTs   2.34   PC3_cells, EB_cells, OVCAR_cells       129079   N91011   Hs.108502   ESTs   2.34   Lu_AD_H23, Lu_SC_H69, Lu_AD_358       123517   AA608525   Hs.243059   EST   2.34   Lu_SC_H345, PC3_cells, MS-MDA-435s       126239   AA527215   Hs.75879   ribosomal protein L19   2.34   BT474_cells, Lu_LC_H460, Lu_AD_H23       124440   N46435       ESTs   2.34   Lu_SC_H69, HT29_cells, MS-MDA-435s       111468   R05809   Hs.205481   ESTs   2.34   Lu_AD_H23, PRSC_log, Lu_SQ_H520       129560   H18428   Hs.113613   ESTs; Moderately similar to !!!! ALU SUB   2.34   Lu_SC_H69, Lu_SC_H345, LNCaP_cells       104857   AA043219   Hs.19058   ESTs   2.34   Lu_AD_H23, Lu_SC_H345, Lu_SC_H345       109647   F04587   Hs.28241   ESTs   2.34   HS578T_cells, A549_cells, CALU6_cells       117160   H97817   Hs.183302   ESTs   2.34   EB_cells, Fibroblasts 2, Lu_SC_H69       112352   R58974   Hs.167343   ESTs   2.34   EB_cells, Lu_SC_H345, HT29_cells       113653   T95745   Hs.187433   ESTs   2.34   MB-MDA-435s, MB-MDA-453, Lu_SC_H345       131606   W56804   Hs.29385   AFG3 (ATPase family gene 3; yeast)-like   2.34   OVCAR_cells, Fibroblasts 2, MB-MDA-435s       101525   M29536   Hs.12163   eukaryotic translation initiation factor   2.34   EB_cells, Caco2, DU145_cells       125921   AA775029   Hs.122591   ESTs   2.33   293T_cells, PRSC_log, Lu_SC_H345       125775   AA213555   Hs.29205   alpha integrin binding protein 63   2.33   EB_cells, DU145_cells, LNCaP_cells       108743   AA126917   Hs.71074   ESTs   2.33   Lu_AD_H23, Lu_AD_358, Lu_LC_H460       133735   AC002045   Hs.251928   nuclear pore complex interacting protein   2.33   LNCaP_cells, Lu_SC_H69, DU145_cells       120403   AA234916   Hs.243851   ESTs   2.33   MB231_cells, Lu_SC_H345, Lu_SC_H69       134998   R02207   Hs.92679   ESTs; Weakly similar to microtubule-base   2.33   LNCaP_cells, BT474_cells, MCF7       108456   AA079326   Hs.143654   ESTs   2.33   HT29_cells, Lu_AD_H23, RPWE_2       130552   M86667   Hs.179662   nucleosome assembly protein 1-like 1   2.33   EB_cells, A549_cells, DU145_cells       111114   N63391   Hs.9238   ESTs   2.33   Caco2, EB_cells, MB-MDA-453       127767   AI269498   Hs.125543   ESTs; Moderately similar to TADA1 protei   2.33   CALU6_cells, 293T_cells, PC3_cells       106546   AA454725   Hs.21056     H sapiens  mRNA from chromosome 5q21-22;   2.33   OVCAR_cells, Caco2, LNCaP_cells       122379   AA446110   Hs.250989   EST   2.33   BT474_cells, Fibroblasts 2, MB-MDA-435s       133650   D84294   Hs.118174   tetratricopeptide repeat domain 3   2.33   Lu_SC_H345, EB_cells, EB_cells       106434   AA449099   Hs.8151   ESTs; Weakly similar to atopy related au   2.33   EB_cells, LNCaP_cells, Caco2       105297   AA233451   Hs.183858   transcriptional intermediary factor 1   2.33   EB_cells, LNCaP_cells, Caco2       115976   AA447442   Hs.86327   ESTs   2.33   EB_cells, 293T_cells, Lu_SC_H69       105788   AA351031   Hs.23965   solute carrier family 22 (organic anion   2.33   EB_cells, Lu_AD_H23, Lu_SC_H345       113774   W04550   Hs.9927     H sapiens  mRNA; cDNA DKFZp564D156 (from   2.32   OVCAR_cells, EB_cells, Lu_SC_H69       110617   H68772   Hs.35820   ESTs; Weakly similar to b3418.1 [ H.sapie     2.32   Lu_SC_H345, Lu_AD_H23, PRSC_con       102234   U26312   Hs.8123   chromobox homolog 3 (Drosophila HP1 gamm   2.32   CALU6_cells, LNCaP_cells, A549_cells       114777   AA151699   Hs.184519   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.32   HT29_cells, Fibroblasts 2, Lc_SC_H345       125518   R20148   Hs.193851   ESTs   2.32   HT29_cells, HMEC (total RNA), MB231_cells       130814   AA256695   Hs.19813   ESTs   2.32   MB-MDA-435s, Lu_SC_H69, PRSC_log       123473   AA599143       ESTs; Moderately similar to !!!! ALU SUB   2.32   LNCaP_cells, DU145_cells, Lu_H345       134310   AA313414   Hs.8148     H sapiens  clone 24856 mRNA seq; complete   2.32   PC3_cells, LNCaP_cells, OVCAR_cells       119192   R85375   Hs.237262   EST   2.32   Lu_SC_H69, PRSC_log, PRSC_con       114391   AA004876   Hs.133100   ESTs   2.32   PC3_cells, 293T_cells, 293T_cells       119133   R49144   Hs.119756   ESTs   2.32   PRSC_log, 293T_cells, 293T_cells       109710   F09792   Hs.12929   ESTs   2.32   Lu_AD_H23, Lu_SC_H69, Lu_SC_H345       116726   F13681   Hs.42309   ESTs   2.32   MCF7, BT474_cells, MB-MDA-453       133206   R32993   Hs.6762   ESTs; Weakly similar to similar to leucy   2.31   DU145_cells, 293T_cells, EB_cells       135163   AA125988   Hs.199955   ESTs   2.31   Lu_SC_H345, LNCaP_cells, DU145_cells       111219   N68836   Hs.19247   ESTs   2.31   OVCAR_cells, LNCaP_cells, 293T_cells       110283   H29565   Hs.12271   ESTs   2.31   BT474_cells, MB231_cells, MB231_cells, MB-MDA-453       103772   AA092473   Hs.8123   chromobox homolog 3 (Drosophila HP1 gamm   2.31   CALU6_cells, MCF7, DU145_cells       122766   AA459386   Hs.194058   ESTs; Weakly similar to atypical PKC spe   2.31   HT_cells, BT474_cells, HMEC       120886   AA365566   Hs.132736   ESTs; Weakly similarto allograft inflam   2.31   DU145_cells, A549_cells, Lu_LC_H460       123512   AA600248   Hs.142245   HERV-H LTR-associating 3   2.31   PC3_cells, 293T_cells, DU145_cells       106644   AA460239   Hs.12680   ESTs   2.31   HS578T_cells, MB231_cells, Lu_SQ_H520       127359   H72971       KIAA0277 gene product   2.31   Lu_SC_H345, DU145_cells, OVCAR_cells       105919   AA402494   Hs.3990   ESTs   2.31   HS578T_cells, DU145_cells, LNCaP_cells       125241   W86291   Hs.121593   ESTs   2.3   HMEC, HMEC (total RNA), EB_cells       104624   AA001936   Hs.184721   ESTs   2.3   DU145_cells, PC3_cells, PRSC_log       128765   AA101767   Hs.10494   ESTs   2.3   EB_cells, HMEC (total RNA), Lu_LC_H460       108360   AA071539       zm74b6.s1 Stratagene neuroepithelium (#9   2.3   HT29_cells, RPWE_2, Lu_AD_H23                   HYDROXYSTEROID DEHYDROGENASEIDELTA-5-DEL       115682   AA410300   Hs.44618   ESTs   2.3   HT29_cells, Lu_SQ_H520, Lu_AD_H23       134528   M23161   Hs.84775   Human transposon-like element mRNA   2.3   EB_cells, CALU6_cells, A549_cells       111091   N59858   Hs.33032     H sapiens  mRNA; cDNA DKFZp434N185 (from   2.3   LNCaP_cells, DU145_cells, PRSC_log       134044   AA262475   Hs.78746   phosphodiesterase 8A   2.29   DU145_cells, A549_cells, MCF7       118229   N62339   Hs.180532   heat shock 90 kD protein 1; alpha   2.29   MCF7, DU145_cells, EB_cells       110188   H20522   Hs.20969   ESTs   2.29   Fibroblasts 2, MB-MDA-435s, Lu_LC_H460       125073   T87185   Hs.193638   ESTs; Weakly similar to !!!! ALU CLASS C   2.29   EB_cells, Lu_SC_H345, Lu_SC_H69       111495   R07210   Hs.19913   ESTs   2.29   CALU6_cells, EB_cells, MCF7       124024   F03077   Hs.106672   ESTs   2.29   HS578T_cells, RPWE_2, Lu_AD_358       128230   AA984074   Hs.176757   ESTs   2.29   LNCaP_cells, DU145_cells, OVCAR_cells       125471   AA477571   Hs.152601   UDP-glucose ceramide glucosyltransferase   2.29   DU145_cells, PRSC_con, PRSC_log       120734   AA299949       EST12545 Uterus tumor I  H sapiens  cDNA 3   2.28   Lu_AD_H23, Lu_SC_H345, Lu_SC_H69       134349   AA406373   Hs.8208   ESTs   2.28   DU145_cells, PC3_cells, LNCaP_cells       123412   AA521443   Hs.187763   ESTs   2.28   BT474_cells, BT474_cells, Lu_SC_H169       116297   AA489042   Hs.59498   ESTs   2.28   EB_cells, 293T_cells, MB-MDA-453       104476   N33807   Hs.223014   protease; serine; 15   2.28   LNCaP_cells, MCF7, PC3_cells       101004   J04101   Hs.248109   v-ets avian erythroblastosis virus E26 o   2.28   HT29_cells, MB-MDA-435s, HMEC (total RNA)       109991   H09813   Hs.12896   KIAA1034 protein   2.28   EB_cells, CALU6_cells, 293T_cells       118934   N92571   Hs.54808   ESTs   2.28   HS578T_cells, 293T_cells, A549_cells       125096   T94328   Hs.194533   ESTs   2.28   Lu_SC_H345, Lu_SC_H69, 293T_cells       117514   N32226   Hs.124058   ESTs   2.28   CALU6_cells, HMEC, Lu_AD_H23       132792   AA401903   Hs.242985   hemoglobin; gamma G   2.28   OVCAR_cells, Lu_SC_H69, MCF7       129009   AA131421   Hs.107884   ESTs   2.28   Hs578T_cells, CALU6_cells, Caco2       111658   R16981   Hs.15276   ESTs   2.28   MB-MDA-435s, 293T_cells, A549_cells       112322   R55757   Hs.26457   EST   2.28   Lu_SC_H345, Lu_SC_H69, Lu_AD_358       133477   W69310   Hs.740   PTK2 protein tyrosine kinase 2   2.28   EB_cells, PC3_cells, DU145_cells       132149   T10822   Hs.4095   ESTs   2.28   LNCaP_cells, EB_cells, PC3_cells       115119   AA256524   Hs.46847   Human DNA seq from done 30M3 on chromos   2.27   A549_cells, EB_cells, LNCaP_cells                   yeast and archaea bacterial genes; and       102130   U15009   Hs.1575   small nuclear ribonucleoprotein D3 polyp   2.27   LNCaP_cells, Caco2, EB_cells       114343   Z41424   Hs.21259   ESTs   2.27   HT29_cells, OVCAR_cells, Fibroblasts 2       106746   AA476436   Hs.7991   ESTs   2.27   Lu_AD_358, RPWE_2, Lu_AD_H23       119359   T71021   Hs.93334   ESTs; Highly similar to WS basic-helix-I   2.27   Lu_SC_H69, 293T_cells, DU145_cells       106301   AA435867   Hs.168212   kinesin family member 3B   2.27   OVCAR_cells, LNCaP_cells, EB_cells       130280   L13738   Hs.153937   activated p21cdc42Hs kinase   2.27   MB-MDA-453, DU145_cells, DU145_cells       119724   W69468   Hs.47622   ESTs   2.27   PC3_cells, HT29_cells, A549_cells       108960   AA150199   Hs.49378   DKFZP586D0919 protein   2.27   EB_cells, HS578T_cells, Lu_AD_358       103489   Y08614   Hs.79090   exportin 1 (CRM1; yeast; homolog)   2.26   EB_cells, CALU6_cells, DU145_cells       107711   AA015736   Hs.220687   ESTs   2.26   EB_cells, Lu_AD_H23, Lu_AD_358       131950   W84704   Hs.35380   ESTs   2.26   HS578T_cells, OVCAR_cells, MB-MDA-435s       107093   AA609600   Hs.10018   ESTs   2.26   LNCaP_cells, OVCAR_cells, DU145_cells       113649   T95641   Hs.16400   ESTs; Weakly similar to Hrs [ H.sapiens ]   2.26   Lu_AD_H23, Lu_SC_H69, PRSC_log       105255   AA227498   Hs.3623   ESTs   2.26   HS578T_cells, 293T_cells, Lu_SC_H345       130094   H43286   Hs.167017   gamma-aminobutyric acid (GABA) B recepto   2.26   Fibroblasts 2, MB231_cells, 293T_cells       111874   R37959   Hs.13358   ESTs   2.26   CALU6_cells, Lu_SQ_H520, 293T_cells       107890   AA026030   Hs.61311   ESTs; Weakly similar to CALPAIN 2; LARGE   2.26   HT29_cells, MB-MDA-453, PC3_cells       124628   N74702   Hs.102834   ESTs   2.26   293T_cells, CALU6_cells, CALU6_cells       119707   W67569   Hs.44143   ESTs; Weakly similar to SNF2alpha protei   2.26   293T_cells, OVCAR_cells, Lu_SC_H345       106737   AA470080   Hs.36237   ESTs; Moderately similar to CGI-34 prote   2.26   LNCaP_cells, DU145_cells, MB-MDA-435s       117305   N22798   Hs.43248   EST   2.26   HT29_cells, BT474_cells, Fibroblasts 2       134470   X54942   Hs.83758   CDC28 protein kinase 2   2.26   DU145_cells, CALU6_cells, LNCaP_cells       130734   T99337   Hs.18624   KIAA1052 protein   2.26   Lu_AD_H23, Lu_SC_H345, Lu_SC_H69       128561   R69227   Hs.101489   ESTs   2.26   Lu_SC_H345, DU145_cells, OVCAR_cells       100670   HG2992-H       Beta-Hexosaminidase, Alpha Polypeptide,   2.26   HT29_cells, BT474_cells, Lu_SC_H345       115953   AA443958   Hs.90960   ESTs   2.26   Caco2, 293T_cells, DU145_cells       129612   H17476   Hs.11615   ESTs; Highly similarto map kinase phosp   2.25   CALU6_cells, LNCaP_cells, PC3_cells       111362   N91973   Hs.23595   deoxyribonuclease III; dnaQ/mutD (E. col   2.25   Lu_SQ_H520, Lu_AD_H23, RPWE_2       116275   AA485453   Hs.250911   interleukin 13 receptor; alpha 1   2.25   OVCAR_cells, 293T_cells, DU145_cells       114461   AA024848   Hs.126705   ESTs   2.25   EB_cells, Lu_AD_H23, Lu_AD_H23       134083   AA278393   Hs.79013   ESTs   2.25   293T_cells, EB_cells, OVCAR_cells       132470   Z24724   Hs.4934     H.sapiens  polyA site DNA   2.25   EB_cells, HS578T_cells, Caco2       114718   AA131328       zo8d1.s1 Stratagene neuroepithelium NT2R   2.25   MB-MDA-435s, HT29_cells, Lu_SC_H69                   SW:COX2_MOUSE P45 CYTOCHROME C OXIDASE P       129499   R40395   Hs.242908   lecithin-cholesterol acyltransferase   2.25   HMEC (total RNA), Fibroblasts 2, HMEC       124758   R38422   Hs.169168   ESTs   2.25   293T_cells, RPWE_2, Lu_LC_H460       130301   X83127   Hs.172471   potassium voltage-gated channel; shaker-   2.25   EB_cells, OVCAR_cells, A549_cells       131263   R38334   Hs.24950   regulator of G-protein signalling 5   2.25   Lu_AD_H23, EB_cells, Lu_SC_H69       107159   AA621340   Hs.10600   ESTs; Weakly similarto ORF YKR081c [S.c   2.25   LNCaP_cells, HMEC, EB_cells       133262   N72009   Hs.206710   ESTs   2.24   Lu_SC_H345, DU145_cells, LNCaP_cells       132985   AA093619   Hs.62113   KIAA0717 protein   2.24   EB_cells, Lu_AD_H23, Lu_AD_358       114172   Z39043   Hs.21421   ESTs; Weakly similar to cysteine desulfu   2.24   293T_cells, CALU6_cells, Lu_SQ_H520       127847   AA913387   Hs.126717   ESTs   2.24   LNCaP_cells, DU145_cells, Lu_SC_H69       106499   AA452244   Hs.16727   ESTs   2.24   Lu_SC_H345, MB-MDA-453, Lu_SC_H69       105095   AA150088   Hs.27023   KIAA0917 protein   2.24   DU145_cells, LNCaP_cells, CALU6_cells       108876   AA134361   Hs.191453   ESTs   2.24   EB_cells, Lu_SC_H345, Lu_AD_H23       121971   AA429667   Hs.120405   ESTs   2.24   Lu_AD_H23, 293T_cells, CALU6_cells       114334   Z41342   Hs.22941   ESTs   2.24   DU145_cells, PC3_cells, EB_cells       114565   AA063001   Hs.103527   SH2 domain protein 2A   2.24   Lu_LC_H460, MCF7, HMEC (total RNA)       115766   AA421761   Hs.77603   ESTs   2.24   Fibroblasts 2, MB-MDA-435s, MB231_cells       130989   AA608546   Hs.21906   ESTs   2.24   PC3_cells, LNCaP_cells, DU145_cells       116304   AA489461   Hs.64742     H sapiens  mRNA for KIAA0540 protein; par   2.24   BT474_cells, EB 13  cells, LNCaP_cells       111154   N66545   Hs.29169   ESTs   2.24   OVCAR_cells, MB-MDA-435s, HMEC       105561   AA262881   Hs.16029   ESTs; Weakly similar to altematively sp   2.23   HS578T_cells, A549_cells, HMEC       105939   AA404421   Hs.12258   ESTs   2.23   EB 13  cells, LNCaP_cells, DU145_cells       126379   AI085342   Hs.166146   Homer; neuronal immediate earty gene; 3   2.23   HS578T_cells, PC3_cells, RPWE_2       106610   AA458882   Hs.4832   ESTs; Moderately similar to Lasp-1 prote   2.23   DU145_cells, MCF7, Lu_SC_H345       132786   AA424545   Hs.56851     H sapiens  mRNA expressed in placenta   2.23   EB_cells, Lu_AD_H23, Fibroblasts 2       107206   D20728   Hs.30767   ESTs   2.23   BT474_cells, Fibroblasts 2, MB-MDA-435s       133708   R42172   Hs.75667   synaptophysin   2.23   Lu_SC_H345, CALU6_cells, Lu_SC_H69       135123   AA227567   Hs.9482   target of myb 1 (chicken) homolog   2.23   BT474_cells, MB231_cells, EB_cells       132156   AA157401   Hs.4113   S-adenosylhomocysteine hydrolase-like 1   2.23   DU145_cells, 293T_cells, LNCaP_cells       116934   H75624   Hs.39662   ESTs   2.23   CALU6_cells, Lu_SC_H345, Lu_LC_H460       133660   R87373       ym88e05.r1 Soares aduh brain N2b4HB55Y   2.23   DU145_cells, A549_cells, PC3_cells                   IMAGE: 166016 5′, mRNA seq.       119458   W23633   Hs.125043   ESTs   2.23   293T_cells, MB-MDA-453, OVCAR_cells       101247   L33801   Hs.78802   glycogen synthase kinase 3 beta   2.23   LNCaP_cells, EB_cells, MB-MDA-435s       126008   AA253460       zs06f04.s1 NCI_CGAP_GCB1  H sapiens  cDNA   2.23   HT29_cells, PRSC_log, Fibroblasts 2       122938   AA477119       zu37c7.s1 Soares ovary tumor NbHOT  H sap     2.23   PC3_cells, MCF7, MB-MDA-434s                   TR: G288289 G288289 MITOCHONDRIAL D-LOOP       114148   Z38804   Hs.184777   ESTs; Moderately similar to OPIOID BINDI   2.23   HS578T_cells, Fibroblasts 2, LuSC_H345                   MOLECULE PRECURSOR [ H.sapiens ]       103433   X98001   Hs.78948   Rab geranylgeranyltransferase; beta subu   2.22   LNCaP_cells, EB_cells, 293T_cells       132954   AA027112   Hs.216194   ESTs   2.22   EB_cells, Lu_AD_H23, Fibroblasts 2       133228   N90029   Hs.6831     H sapiens  clone 1400 unknown protein mRN   2.22   293T_cells, PC3_cells, DU145_cells       103891   AA242887   Hs.124186   ring finger protein 2   2.22   EB_cells, Lu_SC_H69, Lu_SC_H345       124883   R75630   Hs.177242   ESTs   2.22   EB_cells, Lu_AD_H23, Lu_SC_H345       109921   H05734   Hs.30559   ESTs   2.22   Lu_SQ_H520, 293T_cells, RPWE_2       127306   AI305162   Hs.193687   ESTs   2.22   MCF7, HT29_cells, MB-MDA-453       102707   U77456   Hs.78103   nucleosome assembly protein 1-like 4   2.22   Caco2, EB_cells, CALU6_cells       106193   AA427625   Hs.23272   ESTs   2.22   293T_cells, EB_cells, A549_cells       118819   N79045   Hs.50800   ESTs; Weakly similar to !!!! ALU SUBEAMI   2.22   Lu_SC_H345, LuSC_H69, DU145_cells       134326   U16306   Hs.81800   chondroitin sulfate proteoglycan 2 (vers   2.22   HS578T_cells, PRSC_log, CALU6_cells       112241   R51248   Hs.16027   ESTs   2.22   293T_cells, HMEC (total RNA), HMEC (total RNA)       123693   AA609591   Hs.112728   ESTs   2.22   HT29_cells, HMEC (total RNA), BT474_cells       129052   AA496297   Hs.182740   ribosomal protein S11   2.22   EB_cells, Lu_AD_H23, Lu_AD_358       122481   AA448271   Hs.99126   ESTs   2.21   Lu_AD_H23, HT29_cells, Lu_AD_358       128895   R37753   Hs.106985   ESTs   2.21   EB_cells, Lu_AD_H23, Lu_SC_H345       124691   R05835   Hs.110153   ESTs; Weakly similar to B-CELL GROWTH FA   2.21   EB_cells, Lu_AD_H23, Lu_AD_358       131556   AA442853   Hs.2869   cyclin-dependent kinase 5; regulatory su   2.21   HT29_cells, Lu_LC_H460, Lu_SC_H69       128869   AA424570   Hs.106736   ESTs   2.21   EB_cells, Lu_AD_H23, Lu_SC_H69       107114   AA610089   Hs.11776   U4/U6-associated RNA splicing factor   2.21   MCF7, Lu_SC_H345, DU145_cells       106255   AA431191   Hs.161489   ESTs   2.21   EB_cells, Caco2, DU145_cells       130724   AA370091   Hs.179680   ESTs   2.2   EB_cells, Lu_AD_H23, Lu_SC_H69       105483   AA255874   Hs.23458   ESTs   2.2   LNCaP_cells, DU145_cells, PC3_cells       118970   N93503   Hs.54961   stoned B/TFIIA-alpha/beta like factor   2.2   293T_cells, HS578T_cells, OVCAR_cells       120805   AA346041   Hs.96844   ESTs   2.2   HT29_cells, HS578T_cells, 293T_cells       106158   AA425382   Hs.6553   ESTs   2.2   CALU6_cells, PC3_cells, EB_cells       102121   U14391   Hs.82251   myosin IC   2.2   A549_cells, EB_cells, Caco2       109446   AA232125   Hs.87062   ESTs   2.2   HT29_cells, Lu_LC_H460, CALU6_cells       129515   AA490882   Hs.112227   ESTs   2.2   Lu_SC_H345, BT474_cells, Caco2       113128   T49325   Hs.8977   ESTs   2.2   Lu_SQ_H520, Lu_AD_H23, Lu_AD_358       127289   AI041014   Hs.220752   ESTs   2.2   EB_cells, Lu_AD_H23, Lu_AD_H23       129912   AA047344   Hs.107213   ESTs; Highly similar to NY-REN-6 antigen   2.2   CALU6_cells, A549_cells, EB_cells       115700   AA411655   Hs.67709   ESTs   2.2   OVCAR_cells, EB_cells, Caco2       106267   AA431873   Hs.4988     H sapiens  clone 24711 mRNA seq   2.2   Lu_SQ_H520, EB_cells, PC3_cells       112881   T03593   Hs.182814   ESTs   2.19   A549_cells, OVCAR_cells, 293T_cells       116902   H70739       yu69f11.s1 Weizmann Olfactory Epithelium   2.19   LNCaP_cells, DU145_cells, PC3_cells                   IMAGE: 239085 3′ similar to contains LTR       105621   AA280865   Hs.6375     H sapiens  mRNA; cDNA DKFZp564K0222 (from   2.19   HMEC, Caco2, HMEC (total RNA)       126991   R31652   Hs.821   biglycan   2.19   Fibroblasts 2, LuSC_H69, HS578T_cells       125466   R08234   Hs.180461   ESTs   2.19   Lu_AD_358, Lu_AD_H23, Lu_SQ_H520       108491   AA082973       zn7g1.s1 Stratagene hNT neuron (#937233)   2.19   Lu_AD_358, RPWE_2, Lu_LC_H460                   to gb:M3672 6S RIBOSOMAL PROTEIN L7A (H       109978   H09356   Hs.22528   ESTs   2.19   PRSC_log, Lu_SC_H345, Lu_SC_H69       106990   AA521354   Hs.24758   ESTs   2.19   EB_cells, LNCaP_cells, OVCAR_cells       122362   AA443919   Hs.96840   ESTs   2.19   EB_cells, Lu_AD_358, PRSC_con       125367   AI016490   Hs.81964   SEC24 ( S. cerevisiae ) related gene famil   2.19   HT29_cells, Lu_SC_H69, Lu_AD_H23       110716   H97188   Hs.35096   ESTs   2.19   DU145_cells, Fibroblasts 2, PRSC_con       129297   R11267   Hs.180570     H sapiens  chromosome 19; cosmid F22329   2.19   293T_cells, MB-MDA-435s, A549_cells       104992   AA102652   Hs.22753   ESTs; Weakly similar to coded for by C.   2.18   MCF7, MB-MDA-453, Lu_SQ_H520       119896   W84738   Hs.137319   ESTs   2.18   293T_cells, 293T_cells, OVCAR_cells       118594   N69022   Hs.49599   ESTs   2.18   Lu_SC_H69, Lu_AD_H23, Lu_SC_H345       129786   H98977   Hs.246109   ESTs   2.18   293T_cells, 293T_cells, 293T_cells       104325   D81608   Hs.150675   polymerase (RNA) II (DNA directed) polyp   2.18   PC3_cells, Lu_SC_H345, LNCaP_cells       123022   AA480909       aa28f10.s1 NCI_CGAP_GCB1  H sapiens  cDNA   2.18   OVCAR_cells, DU145_cells, LNCaP_cells                   Alu repetitive element; contains element       133572   W94333   Hs.7499   translocase of inner mitochondrial membr   2.18   Caco2, LNCaP_cells, Lu_SQ_H520       133363   AA479713   Hs.71962   ESTs   2.18   EB_cells, Lu_AD_H23, Fibroblasts 2       135361   AA053319   Hs.167700   ESTs   2.18   EB_cells, 293T_cells, Caco2       128319   AA808904   Hs.115095   ESTs; Weakly similar to RHO-RELATED GTP-   2.18   Lu_SC_H345, OVCAR_cells, DU145_cells       128660   AA011597   Hs.177398   ESTs   2.18   EB_cells, Lu_AD_H23, Lu_SQ_H520       114877   AA235618   Hs.205125   ESTs   2.18   DU145_cells, 293T_cells, OVCAR_cells       125925   H28737       ESTs; Moderately similar to !!!! ALU SUB   2.18   Lu_SC_H69, Lu_SC_H345, HS578T_cells       113427   T85105   Hs.15471   ESTs   2.18   EB_cells, Lu_AD_H23, Lu_SC_H69       117500   N31909   Hs.44278   ESTs   2.18   PRSC_con, Lu_SC_H345, PRSC_log       131384   F13608   Hs.26226   ESTs   2.18   293T_cells, LNCaP_cells, OVCAR_cells       134499   U70370   Hs.84136   paired-like homeodomain transcnption fa   2.18   Caco2, BT474_cells, MB231_cells       128154   AA922969   Hs.127100   ESTs   2.17   MB-MDA-453, MB-MDA-453, Lu_SC_H345       134585   T48154   Hs.168655     H sapiens  mRNA for H-2K binding factor-2   2.17   LNCaP_cells, 293T_cells, PRSC_log       104987   AA101723   Hs.16683   ESTs   2.17   EB_cells, MCF7, DU145_cells       132992   AA091017   Hs.6226   ESTs   2.17   Caco2, LNCaP_cells, DU145_cells       135311   M36089   Hs.98493   X-ray repair complementing defective rep   2.17   HMEC (total RNA), Fibroblasts 2, HMEC       113171   T54613   Hs.9761   EST   2.17   HT29_cells, PRSC_con, Lu_SQ_H520       117736   N46999   Hs.46648   ESTs   2.16   PRSC_log, OVCAR_cells, A549_cells       125181   W58461   Hs.12396   ESTs   2.16   LNCaP_cells, DU145_cells, 293T_cells       120187   Z40251   Hs.56974   ESTs   2.16   LNCaP_cells, MB-MDA-453, HMEC (total RNA)       100308   D50532   Hs.54403   macrophage lectin 2 (calcium dependent)   2.16   HT29_cells, Lu_AD_H23, Lu_AD_H23       110960   N50887   Hs.26549   ESTs; Weakly similar to KIAA0449 protein   2.16   Caco2, A549_cells, LNCaP_cells       113608   T93113       ESTs; Moderately similar to !!!! ALU SUB   2.16   Lu_SC_H69, CALU6_cells, 293T_cells       107538   Z21089   Hs.50094   ESTs; Weakly similar to KALIRIN [ R.norve     2.16   HS578T_cells, 293T_cells, DU145_cells       128703   S76992   Hs.104005   vav 2 oncogene   2.16   RPWE_2, Lu_SC_H69, HT29_cells       126065   AI366484       ESTs   2.16   293T_cells, CALU6_cells, A549_cells       130000   AA465727   Hs.124084   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.16   DU145_cells, LNCaP_cells, OVCAR_cells       120407   AA235040   Hs.107283   ESTs   2.16   EB_cells, 293T_cells, A549_cells       121199   AA400371   Hs.97792   ESTs   2.16   Lu_AD_358, Lu_AD_H23, A549_cells       114963   AA243867   Hs.193055   ESTs   2.16   DU145_cells, PRSC_con, LNCaP_cells       100343   D63874   Hs.189509   high-mobility group (nonhistone chromoso   2.15   CALU6_cells, MB-MDA-453, Caco2       125077   T88822       yd32f5.s1 Soares fetal liver spleen 1NFL   2.15   Lu_AD_H23, Lu_SC_H69, Lu_SC_H345       117286   N22181       yw36d12.s1 Morton Fetal Cochlea  H sapien     2.15   293T_cells, Lu_Sc_H345, Lu_SC_H69       132876   AA130603   Hs.169683   ESTs; Moderately similarto !!!! ALU SUB   2.15   EB_cells, LNCaP_cells, HS578T_cells       133834   AA147510   Hs.154737   serine protease; umbilical endothelium   2.15   DU145_cells, EB_cells, Caco2       126908   AA169866       ESTs; Weakly similar to !!!! ALU SUBFAMI   2.15   DU145_cells, LNCaP_cells, OVCAR_cells       106900   AA490142   Hs.6193   ESTs   2.15   Fibroblasts 2, Lu_AD_H23, PRSC_con       129398   AA437374   Hs.234573     H sapiens  mRNA for TL132   2.15   MCF7, DU145_cells, LNCaP_cells       114512   AA044274   Hs.165215   ESTs   2.15   Lu_AD_358, MB-MDA-453, HS578T_cells       134381   U56637   Hs.184270   capping protein (actin filament) muscle   2.15   LNCaP_cells, EB_cells, PC3_cells       118843   N80671   Hs.220255   ESTs   2.14   EB_cells, DU145_cells, MCF7       115526   AA342049   Hs.69606   ESTs   2.14   293T_cells, Caco2, Lu_SC_H69       123460   AA598981   Hs.251122   EST   2.14   Lu_SC_H345, DU145_cells, MCF7       119812   W73951   Hs.58348   ESTs; Weakly similar to CORNIFIN A [H.sa   2.14   293T_cells, HS578T_cells, CALU6_cells       105263   AA227926   Hs.6682   ESTs   2.14   A549_cells, HMEC (total RNA), EB_cells       129242   W81679   Hs.5174   ribosomal protein S17   2.14   293T_cells, CALU6_cells, HMEC (total RNA)       132348   AA037285   Hs.170311   heterogeneous nuclear ribonucleoprotein   2.14   A549_cells, HT29_cells, Lu_SQ_H520       114425   AA015763   Hs.132812   ESTs   2.14   293T_cells, HS578T_cells, PRSC_con       127759   AI369384       arylsulfatase D   2.14   DU145_cells, LNCaP_cells, EB_cells       134069   U29607   Hs.78935   methionine aminopeplidase; elF-2-associa   2.14   Lu_SC_H345, DU145_cells, MCF7       116158   AA461187   Hs.61762   ESTs   2.14   Lu_SC_H69, MCF7, MB-MDA-453       125627   R35166   Hs.14881   ESTs   2.14   HT29_cells, Fibroblasts 2, BT474_cells       118684   N71364   Hs.109510   ESTs   2.14   OVCAR_cells, PRSC_con, HS578T_cells       119419   T97977   Hs.60260   ESTs   2.14   Lu_AD_H23, Lu_SQ_H520, Lu_SQ_H520       133097   N67515   Hs.6479   ESTs; Weakly similar to KIAA0872 protein   2.14   EB_cells, Lu_AD_H23, Lu_AD_358       112121   R45445   Hs.252723     H sapiens  mRNA; cDNA DKFZp434D115 (from   2.13   Lu_AD_H23, Lu_AD_358, BT474_cells       114894   AA236019   Hs.188803   ESTs   2.13   MB-MDA-453, MCF7, Lu_SQ_H520       124087   H08773       y194d5.s1 Soares infant brain 1NIB  H sap     2.13   Lu_SC_H69, Fibroblasts 2, HMEC (total RNA)       111902   R39191   Hs.109445   KIAA1020 protein   2.13   Caco2, 293T_cells, Lu_SC_H69       119943   W86835   Hs.14158   copine III   2.13   LNCaP_cells, PC3_cells, HS578T_cells       109276   AA196306   Hs.86045   ESTs   2.13   Lu_SC_H345, Lu_SC_H69, Lu_LC_H460       117351   N24581   Hs.43230   ESTs   2.13   HS578T_cells, CALU6_cells, PRSC_con       116046   AA453461   Hs.94491     H sapiens  clone 23585 mRNA seq   2.13   LNCaP_cells, Caco2, EB_cells       112785   R96478   Hs.16586   ESTs   2.13   EB 13  cells, Lu_AD_H23, Lu_SC_H69       115835   AA428576   Hs.41371   ESTs   2.13   EB_cells, Lu_SC_H345, OVCAR_cells       127499   T49891   Hs.119252   tumor protein; translationally-controlle   2.13   EB_cells, PRSC_con, LNCaP_cells       129951   AA019475   Hs.74615   platelet-derived growth factor receptor,   2.13   EB_cells, Lu_AD_H23, Lu_SC_H69       124270   H79560   Hs.107840   ESTs   2.13   OVCAR_cells, 293T_cells, 293T_cells       133766   D52420   Hs.184326   cell division cycle 10 (homologous to CD   2.12   CALU6_cells, DU145_cells, PC3_cells       109248   AA194720   Hs.189996   ESTs; Highly similar to sec61 homolog [H   2.12   HT29_cells, MB231_cells, HMEC (total RNA)       106724   AA465226   Hs.28631   ESTs   2.12   EB_cells, 293T_cells, DU145_cells       100571   HG2264-H       Atpase, Ca2+ Transporting, Plasma Membra   2.12   EB_cells, Lu_AD_H23, Lu_SC_H69       133017   AA450187   Hs.178518   ESTs   2.12   OVCAR_cells, PC3_cells, 293T_cells       124313   H94650   Hs.108002   ESTs   2.12   MB-MDA-453, Lu_SC_H345, HT29_cells       113059   T26925   Hs.172684   vesicle-associated membrane protein 8 (e   2.12   MB-MDA-453, PC3_cells, LNCaP_cells       113241   T63313   Hs.226136   ESTs; Moderately similar to !!!! ALU SUB   2.12   HMEC (total RNA), BT474_cells, HMEC       111952   R40782   Hs.21296   ESTs   2.12   HT29_cells, PC3_cells, A549_cells       113965   W86519   Hs.19631   ESTs   2.12   PC3_cells, EB_cells, LNCaP_cells       108059   AA043944   Hs.62663   ESTs   2.12   EB_cells, OVCAR_cells, 293T_cells       124235   H63994   Hs.221134   ESTs   2.12   Fibroblasts 2, MB-MDA-453, PRSC_con       106400   AA447621   Hs.31257   ESTs   2.12   DU145_cells, EB_cells, Caco2       119590   W44798   Hs.55876   ESTs   2.12   PRSC_log, Lu_SC_H69, Lu_SC_H345       112434   R63068   Hs.159793   EST   2.11   HS578T_cells, LNCaP_cells, OVCAR_cells       122731   AA457549       aa92b1.s1 Stratagene fetal retina 93722   2.11   MB-MDA-453, RPWE_2, MCF7                   gb:X5275_ma3 LEUKOSIALIN PRECURSOR (HU       115348   AA281562   Hs.88860   ESTs   2.11   EB_cells, Lu_AD_H23, Fibroblasts 2       128873   AA226768   Hs.109483   ESTs; Weakly similar to predicted using   2.11   MB-MDA-435s, EB_cells, LNCaP_cells       133742   T54301   Hs.75844   ESTs   2.11   EB_cells, CALU6_cells, DU145_cells       102099   U11870   Hs.194778   interleukln 8 receptor alpha   2.11   Lu_AD358, PC3_cells, PRSC_con       125840   H05787   Hs.12064   ubiquitin specific protease 22   2.11   EB_cells, LNCaP_celis, Caco2       106501   AA256604   Hs.31930   ESTs   2.1   Fibroblasts 2, HS578T_cells, MB-MDA-4355       111576   R10334   Hs.15489   ESTs   2.1   Lu_SC_H69, PRSC_log, Lu_SC_H345       104275   C02170   Hs.39387   ESTs; Weakly similar to weak similarity   2.1   HT29_cells, MB231_cells, Lu_SC_H69       117803   N48620   Hs.28483   pregnancy specific beta-1-glycoprotein 9   2.1   HT29_cells, HMEC, RPWE_2       122725   AA457407   Hs.152204   transmembrane protease; serine 2   2.1   Lu_SC_H69, Lu_LC_H450, Lu_SC_H345       120987   AA398233   Hs.111894   KIAA0108 gene product   2.1   Fibroblasts 2, PRSC_con, MCF7       105932   AA403305   Hs.12185   ESTs; Weakly similar to myosin phosphata   2.1   LNCaP_cells, MCF7, OVCAR_cells       118398   N64706   Hs.137282   ESTs   2.1   Lu_SC_H345, HT29_cells, HMEC       103679   Z86000       Human DNA seq from PAC 151B14 onchromos   2.1   CALU6_cells, A549_cells, Lu_SC_H345                   receptor subtype 3 (SSTR3), tRNA, ESTs,       130303   L40392   Hs.180789     H sapiens  (clone S164) mRNA; 3′ end of c   2.1   PC3_cells, DU145_cells, LNCaP_cells       122815   AA461080   Hs.139446   ESTs   2.1   HT29_cells, BT474_cells, MB231_cells       105598   AA279439   Hs.20594   ESTs; Weakly similar to misato [ D.melano     2.1   EB 13  cells, Lu_SC_H345, LNCaP_cells       124889   R69088   Hs.28728   ESTs; Weakly similar to F55A12.9 [C.eleg   2.1   HT_cells, BT474_cells, MB231_cells       129599   F10720   Hs.180804   ESTs   2.1   HS578T_cells, HT29_cells, HT29_cells       110338   H40359   Hs.177256   ESTs   2.09   MCF7, A549_cells, MB-MDA-435s       134092   H17490   Hs.7905   ESTs: Highly similar to sorting nexin 9   2.09   EB_cells, Fibroblasts 2 HS578T_cells       133002   AF006082   Hs.62461   ARP2 (actin-related protein 2; yeast) ho   2.09   EB_cells, HS578T_cells, A549_cells       115570   AA398343   Hs.94943   ESTs   2.09   Lu_SC_H345, PC3_cells, LNCaP_cells       120055   W93299   Hs.59363   ESTs; Weakly similar to cytokeratin 20 [   2.09   HMEC (total RNA), HS578T_cells, HS578T_cells       116332   AA491208   Hs.62620   ESTs   2.09   EB_cells, Lu_AD_H23, Lu_SC_H69       105415   AA243768   Hs.4232   ESTs; Highly similar to match to ESTs Z4   2.09   LNCaP_cells, Lu_AD_H23, MB-MDA-453       116607   D80354   Hs.256321   EST   2.09   LNCaP_cells, DU145_cells, RPWE_2       126731   AA593973   Hs.232217   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.09   MB231_cells, HT29_cells, HMEC       102276   U30999   Hs.10247   activated leucocyte cell adhesion molecu   2.09   PC3_cells, HS578T_cells, DU145_cells       113666   T96077   Hs.17738   EST   2.09   Lu_AD_H23, Lu_AD_H23, Lu_SQ_H520       101183   L19779   Hs.795   H2A histone family; member O   2.09   LNCaP_cells, MCF7, OVCAR_cells       112177   R49025   Hs.22996   ESTs   2.09   Lu_AD_H23, Lu_AD_358, Lu_SC_H69       115038   AA252360   Hs.87968   ESTs   2.08   BT474_cells, MB231_cells, HT29_cells       109638   F04432   Hs.17904   ESTs   2.08   EB_cells, DU145_cells, PC3_cells       109592   F02475   Hs.26370   ESTs   2.08   Lu_AD_H23, Lu_SQ_H520, Lu_LC_H460       133740   U68142   Hs.170160   RAB2: member RAS oncogene family-like   2.08   LNCaP_cells, MB-MDA-453, EB_cells       126716   AA031700   Hs.251962   ESTs   2.08   HS578T_cells, Fibroblasts 2, Lu_SC_H69       124055   F10904   Hs.100516     H sapiens  clone 23605 mRNA seq   2.08   Lu_SC_H345, OVCAR_cells, DU145_cells       113283   T66813   Hs.12947   EST   2.08   EB_cells, Lu_SC_H69, Lu_AD_H23       120097   W95068   Hs.59621   ESTs   2.08   HS578T_cells, A549_cells, CALU6_cells       102066   U08471   Hs.352   folate receptor 3 (gamma)   2.08   EB_cells, Lu_AD_H23, Lu_AD_358       108712   AA121993       zm24d11.s1 Stratagene pancreas (#93728)   2.08   Lu_SQ_H520, HT29_cells, BT474_cells                   similar to gb:Y433 GLUTATHIONE PEROXIDAS       134453   X70683   Hs.83484   SRY (sex determining region Y)-box 4   2.08   EB_cells, Lu_SC_H345, Lu_SC_H69       103883   AA232836   Hs.87363   ESTs   2.08   HT29_cells, 293T_cells, 293T_cells       105313   AA233856   Hs.16930   ESTs   2.08   DU145_cells, MB-MDA-435s, HS578T_cells       113669   T96148   Hs.17762   ESTs   2.08   EB_cells, Lu_SQ_H520, Fibroblasts 2       120380   AA227904   Hs.104223   ESTs   2.08   293T_cells, CALU6_cells, A549_cells       121045   AA398554   Hs.181012   double-stranded RNA-binding zinc finger   2.08   293T_cells, PC3_cells, OVCAR_cells       104949   AA070735   Hs.148090   ESTs   2.08   Lu_SC_H69, Lu_SC_H345, RPWE_2       118751   N74210   Hs.50454   EST   2.08   Lu_AD_H23, Lu_SC_H69, Lu_SC_H345       112399   R60920   Hs.26419     H sapiens  clone 24510 mRNA seq   2.08   EB_cells, Lu_AD_H23, Lu_SC_H69       129994   AA599443   Hs.38194   ESTs; Moderately similar to !!!! ALU SUB   2.08   DU145_cells, EB_cells, HS578T_cells       116402   AA600054   Hs.65302   ESTs   2.08   HT29_cells, BT474_cells, Lu_AD_H23       125307   Z40583   Hs.101259   ESTs   2.08   HMEC, HMEC (total RNA), EB_cells       105047   AA132453   Hs.15396   ESTs   2.08   Caco2, HT29_cells, LNCaP_cells       128659   T95280   Hs.103315   trinucleotide repeat containing 1   2.08   EB_cells, Lu_AD_H23, Lu_SC_H69       122301   AA437378   Hs.98791   ESTs   2.08   Lu_SC_H345, Lu_AD_H23, Lu_AD_358       121974   AA429804   Hs.229675   EST   2.08   HS578T_cells, 293T_cells, OVCAR_cells       116905   H71420       ys8c12.s1 Soares fetal liver spleen 1NFL   2.08   Lu_AD_H23, EB_cells, PRSC_con                   3′ similar to contains Alu repetitive e       106703   AA463979   Hs.21264   KIAA0782 protein   2.08   EB_cells, Caco2, PRSC_con       121908   AA427858   Hs.98534   EST   2.07   293T_cells, Lu_SC_H345, CALU6_cells       135119   T23992   Hs.94769   ESTs; Moderately similar to RAS-RELATED   2.07   HS578T_cells, PRSC_con, OVCAR_cells       103558   Z19574   Hs.2785   keratin 17   2.07   RPWE_2, HMEC (total RNA), HMEC       124209   H57317   Hs.193433   ESTs   2.07   Fibroblasts 2, OVCAR_cells, 293T_cells       133936   AA045083   Hs.77719   gamma-glutamyl carboxylase   2.07   Fibroblasts 2, MB-MDA-453, PRSC_con       116246   AA479961   Hs.42913   ESTs; Highly similar to ubiquilin-conjug   2.07   EB_cells, LNCaP_cells, LNCaP_cells       123230   AA490134   Hs.105308   EST   2.07   Lu_AD_H23, Lu_SC_H69, Lu_SC_H345       127378   AA452696       zx39b05.r1 Soares_total_fetus_Nb2HF8_9w   2.07   HS578T_cells, LNCaP_cells, EB_cells                   to contains Alu repetitive element; cont       110464   H53013   Hs.221901   ESTs   2.07   Fibroblasts 2, Lu_SQ_H520, Lu_SQ_H520       135191   X07619   Hs.169876   cytochrome P450; subfamily IID (debrisoq   2.07   Lu_AD_H23, Lu_SC_H69, Lu_AD_358                   polypeptide 7a (pseudogene)       101267   L36818   Hs.75339   inositol polyphosphate phosphatase-like   2.07   Lu_SC_H345, OVCAR_cells, Caco2       105185   AA191495   Hs.189937   ESTs   2.07   Lu_SC_H69, Lu_AD_H23, Lu_SC_H345       125366   H60192   Hs.76853   ESTs; Weakly similar to human homolog of   2.07   DU145_cells, Lu_LC_H460, Lu_AD_358       117472   N30131   Hs.93738   DKFZP434M098 protein   2.07   EB_cells, Lu_SC_H69, 293T_cells       114235   Z39710   Hs.25341   ESTs   2.07   DU145_cells, BT474_cells, Lu_SC_H69       109081   AA165268   Hs.72488   ESTs   2.07   Lu_SC_H69, Lu_SC_H345, PC3_cells       112596   R78212   Hs.163705   ESTs   2.07   MB-MDA-435s, Lu_SQ_H520, MB-MDA-453       109254   AA194940   Hs.85956   ESTs; Weakly similar to line-1 protein O   2.07   HS578T_cells, 293T_cells, OVCAR_cells       105898   AA401144   Hs.27354   ESTs   2.07   EB_cells, 293T_cells, PRSC_con       116290   AA488691   Hs.57969   phenylalanine-tRNA synthetase   2.06   Lu_AD_H23, Lu_SC_H345, PRSC_log       122529   AA449828   Hs.99229   ESTs   2.06   DU145_cells, HS578T_cells, 293T_cells       104612   R99199   Hs.173063   transducin-like enhancer of split 2: hom   2.06   MB-MDA-435s, 293T_cells, 293T_cells       116465   AA621650   Hs.41045   ESTs; Weakly similar to KIAA0734 protein   2.06   MB231_cells, HT29_cells, Lu_AD_358       123155   AA488414   Hs.76127   hect (homologous to the E6-AP (UBE3A) ca   2.06   DU145_cells, CALU6_cells, PC3_cells                   domain (RLD) 1       126752   AI073373   Hs.183275   ESTs   2.06   LNCaP_cells, EB_cells, DU145_cells       126455   N80749   Hs.111515   ESTs; Weakly similar to predicted using   2.06   CALU6_cells, PRSC_log, OVCAR_cells       129339   R77869   Hs.28506   ESTs   2.06   EB_cells, BT474_cells, Lu_AD_H23       115021   AA252028   Hs.39168   ESTs   2.06   Lu_SQ_H520, Fibroblasts 2, EB_cells       129054   T67231   Hs.168289   succinate dehydrogenase complex; subunit   2.06   Caco2, LNCaP_cells, EB_cells       101261   L35545   Hs.82353   endothelial cell protein C/activated pro   2.06   EB_cells, RPWE_2, DU145_cells       132697   AA281951   Hs.5518     H sapiens  mRNA; cDNA DKFZp566J2146 (from   2.06   OVCAR_cells, LNCaP_cells, DU145_cells       124380   N26536   Hs.84999   ATPase; Cu++ transporting; beta polypept   2.06   Caco2, Caco2, 293T_cells       103967   AA303711   Hs.144700   ephrin-B1   2.06   HT29_cells, HMEC (total RNA), HMEC       119403   T92935   Hs.119908   ESTs; Highly similarto nucleolar protei   2.06   HMEC, EB_cells, HMEC (total RNA)       125755   R66080   Hs.191268     H sapiens  mRNA; cDNA DKFZp434N174 (from   2.06   LNCaP_cells, DU145_cells, OVCAR_cells       101843   M93405   Hs.170008   methylmalonate-semialdehyde dehydrogenas   2.05   LNCaP_cells, MB-MDA-453, EB_cells       113032   T24024   Hs.7387   DKFZPS64B116 protein   2.05   EB_cells, A549_cells, A549_cells       112563   R72632   Hs.29282   ESTs   2.05   MCF7, HS578T_cells, PRSC_con       126432   AA583825   Hs.235860   ESTs   2.05   MB231_cells, HT29_cells, Fibroblasts 2       101636   M57763   Hs.89474   ADP-ribosylation factor 6   2.05   DU145_cells, LNCaP_cells, PC3_cells       125174   W51835   Hs.231082   EST   2.05   26_cells, Fibroblasts 2, Lu_AD_H23       106168   AA425943   Hs.82208   acyl-Coenzyme A dehydrogenase; very long   2.05   OVCAR_cells, PC3_cells, EB_cells       135343   AA236796   Hs.9914   follistatin   2.05   HMEC (total RNA), PC3_cells, HMEC       105267   AA227956   Hs.25348   follistatin-like 3 (secreted glycoprotel   2.05   HMEC, RPWE_2, HMEC (total RNA)       134331   AA452020   Hs.234156   ESTs; Weakly similar to CGI-128 protein   2.05   EB_cells, CALU6_cells, A549_cells       121634   AA417012   Hs.28921   ESTs   2.05   HS578T_cells, EB_cells, Lu_SC_H345       131394   R72637   Hs.26343   ESTs   2.05   EB_cells, Lu_SC_H69, Lu_AD_H23       111526   R05260   Hs.20131   ESTs   2.05   Lu_AD_H23, Lu_SC_H69, BT474_cells       125049   T79840   Hs.111798   ESTs   2.05   HT29_cells, Lu_AD_H23, Lu_SC_H345       120433   AA237077   Hs.180777     H sapiens  mRNA; cDNA DKFZp564M0264 (from   2.05   DU145_cells, CALU6_cells, PC3_cells       129498   AA449789   Hs.75511   connective tissue growth factor   2.05   HS578T_cells, PRSC_log, PRSC_con       127805   AA740921   Hs.1197   heat shock 10 kD protein 1 (chaperonin 10   2.05   DU145_cells, LNCaP_cells, OVCAR_cells       109275   AA196287   Hs.20303   ESTs; Moderately similar to !!!! ALU SUB   2.05   EB_cells, MB-MDA-453, Fibroblasts 2       120683   AA290987   Hs.49657   ESTs; Weakly similar to contains similar   2.04   Lu_AD_358, Lu_SQ_H520, Lu_LC_H460       135415   X60655   Hs.99967   even-skipped homeo box 1 (homolog of Dro   2.04   Lu_AD_H23, RPWE_2, Lu_SQ_H520       132925   AA252759   Hs.238296   DKFZP434A033 protein   2.04   293T_cells, HS578T_cells, LNCaP_cells       101875   M97287   Hs.74592   special AT-rich seq binding protein 1 (b   2.04   EB_cells, Lu_SC_H69, 293T_cells       101453   M22490   Hs.65879   bone morphogenetic protein 4   2.04   PRSC_con, HT29_cells, MB231_cells       129177   T95005   Hs.209587   ESTs   2.04   293T_cells, MB-MDA-435s, Lu_SC_H69       130726   W55946   Hs.18508   putative glycine-N-acyltransferase   2.04   HT29_cells, Fibroblasts 2, MB-MDA-435s       105549   AA262417   Hs.5415   ESTs   2.04   DU145_cells, OVCAR_cells, PC3_cells       124543   N63706   Hs.104573   ESTs   2.04   Caco2, 293T_cells, DU145_cells       123062   AA482069   Hs.100847   ESTs   2.04   Lu_AD_358, HT29_cells, HT29_cells       109464   AA232557   Hs.87100   ESTs   2.04   DU145_cells, Lu_AD_H23, LNCaP_cells       129619   AA610116   Hs.11663   tetraspan NET-6 protein   2.04   BT474_cells, Caco2, LNCaP_cells       127545   AA935809   Hs.115899   ESTs   2.04   BT474_cells, MB-MDA-4355, MB-MDA-453       133068   R73427   Hs.235712   ESTs   2.04   Caco2, OVCAR_cells, MCF7       113609   T93263   Hs.16875   ESTs; Weakly similar to hypothetical pro   2.04   EB_cells, Lu_SC_H345, PRSC_con       106645   AA460270   Hs.27695   midline 1 (Opitz/BBB syndrome)   2.04   A549_cells, 293T_cells, Caco2       126256   Z21124       HSAAADNVE TEST1, Human adult Testis tiss   2.04   Fibroblasts 2, Fibroblasts 2, MCF7       129697   R00541   Hs.172069   DKFZP434C212 protein   2.04   HT29_cells, Lu_SQ_H520, BT474_cells       126730   T19477       A1426R Heart  H sapiens  cDNA clone A1426,   2.04   EB_cells, Lu_AD_H23, Lu_SC_H69       125244   W86466   Hs.132756   ESTs; Weakly similar to KIAA0591 protein   2.04   EB_cells, Lu_AD_H23, Lu_LC_H460       134762   M91036   Hs.242985   hemoglobin; gamma G   2.04   MB231_cells, Lu_AD_358, HT29_cells       119564   W38206       Accession not listed in Genbank   2.04   BT474_cells, HT29_cells, Lu_AD_H23       132523   AB002332   Hs.50722   clock (mouse) homolog   2.04   PC3_cells, OVCAR_cells, PRSC_log       127758   AI337031   Hs.180195   ESTs   2.04   293T_cells, MB-MDA-435s, A549_cells       126471   AA158755   Hs.175652   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.04   EB_cells, Lu_AR_358, Lu_LC_H460       110911   N45120   Hs.22305   ESTs   2.03   Lu_AD_H23, RPWE_2, Lu_LC_H460       122317   AA442742   Hs.8693   ESTs; Weakly similar to !!!! ALU SUSFAMI   2.03   EB_cells, Fibroblasts 2, Lu_SC_H345       100253   D38024   Hs.247951   Humn facioscapulohumeral muscular dystro   2.03   Lu_AD_H23, Lu_AD_358, Lu_SQ_H520       120431   AA236854   Hs.247323     H sapiens  mRNA for G4 protein (G4 gene;   2.03   Lu_SQ_H69, EB_cells, Lu_SC_H345       122449   AA447638   Hs.104977   ESTs   2.03   Lu_SC_H345, Lu_SC_H345, Lu_SQ_H520       100961   J00148       Accession not listed in Genbank   2.03   HT29_cells, BT474_cells, HMEC       130908   W86389   Hs.21122   ESTs; Moderately similar to KIAA0438 [H.   2.03   293T_cells, Lu_SC_H345, OVCAR_cells       102643   U67649       Human bota-galactoside alpha2,6-sialyltr   2.03   HT29_cells, 293T_cells, Lu_SC_H345       127932   AA398510   Hs.133148   ESTs   2.03   EB_cells, Lu_SC_H345, Lu_SC_H69       109207   AA190906   Hs.204692   ESTs   2.03   Lu_SQ_H520, Lu_SQ_H345, Lu_SC_H69       102598   U62962   Hs.106673   eukatyotic translation initiation factor   2.03   EB_cells, DU145_cells, MCF7       124470   N51702   Hs.101392   ESTs   2.03   HT29_cells, Fibroblasts 2, HMEC (total RNA)       104961   AA076672   Hs.33905   ESTs   2.03   Caco2, LNCaP_cells, EB_cells       124164   H30667   Hs.7535   ESTs; Highly similar to COBW-like placen   2.03   CALU6_cells, CALU6_cells, A549_cells       126468   AA242853   Hs.237856   ESTs; Moderately similar to cAMP inducib   2.03   MB231_cells, BT474_cells, Fibroblasts 2       129683   W05348   Hs.158196   DKFZP434B103 protein   2.03   HT29_cells, MB-MDA-435s, Lu_AD_H23       105350   AA235737   Hs.186571   ATPase; Na+/K+ transporting; alpha 3 pol   2.03   MB-MDA-453, Lu_SQ_H520, Lu_AD_358       129794   AA447772   Hs.14520   eukaryotic translation initiation factor   2.03   EB_cells, Lu_AD_358, Lu_AD_H23       115664   AA405974   Hs.54673   tumor necrosis factor (ligand) superfami   2.03   Lu_AD_358, HT29_cells, HT29_cells       119096   R41672   Hs.91471   ATPase type IV; phospholipid transportin   2.03   HT29_cells, MB231_cells, BT474_cells       133866   L36151   Hs.171625   phosphatidylinositol 4-kinase; catalytic   2.03   293T_cells, DU145_cells, LNCaP_cells       132055   N69440   Hs.38132   ESTs   2.03   Lu_SC_H345, MB-MDA-453, MB-MDA-435s       125691   AI034361   Hs.135150   lung type-I cell membrane-associated gly   2.03   Lu_SC_H345, LNCaP_cells, DU145_cells       121376   AA405699   Hs.166232   ESTs; Moderately similar to SODIUM-AND   2.03   LNCaP_cells, HT29_cells, RPWE_2                   TRANSPORTER 2 [ H.sapiens ]       105289   AA233178   Hs.103000   KIAA0831 protein   2.02   PC3_cells, Lu_AD_H23, MB231_cells       100967   J02621   Hs.251064   high-mobility group (nonhistone chromoso   2.02   MCF7, DU145_cells, OVCAR_cells       124430   N38913   Hs.221575   ESTs   2.02   MB-MDA-435s, Fibroblasts 2, EB_cells       128322   AI306331   Hs.133296   ESTs   2.02   HT29_cells, MB-MDA-435s, Lu_SC_H345       131077   X91809   Hs.22698   G alpha interacting protein   2.02   Lu_AD_H23, RPWE_2, MCF7       108033   AA040923   Hs.92200   KIAA0480 gene product   2.02   MCF7, Fibroblasts 2, DU145_cells       107550   AA001045   Hs.46783   ESTs   2.02   DU145_cells, PC3_cells, OVCAR_cells       109475   AA233159   Hs.87131   ESTs   2.02   HT29_cells, MB-MDA-435s, Lu_SC_H69       111400   R00144   Hs.189771   ESTs   2.02   HT29_cells, Fibroblasts 2, HMEC       117516   N32495   Hs.151560   ESTs   2.02   HT29_cells, HMEC (total RNA), Fibroblasts 2       120506   AA257955   Hs.173705   ESTs; Weakly similar to !!!! ALU CLASS C   2.02   MCF7, Fibroblasts 2, LNCaP_cells       130850   N39308   Hs.20237   DKFZPS66C134 protein   2.02   EB_cells, Lu_AD_H23, Lu_LC_H460       123118   AA486571   Hs.105696   ESTs; Moderately similarto !!!! ALU SUB   2.02   CALU6_cells, 293T_cells, PRSC_log       111285   N71704   Hs.4310   eukaryotic translation initiation factor   2.02   293T_cells, PC3_cells, EB_cells       119106   R42362   Hs.91785   ESTs   2.02   CALU6_cells, MB-MDA-453, PC3_cells       111370   N92915   Hs.94031   brefeldin A-inhibited guanine nucleotide   2.02   EB_cells, OVCAR_cells, LNCaP_cells       125013   T67261   Hs.154431   ESTs; Weakly similarto neuronal thread   2.02   Lu_SC_H345, Lu_SC_H69, PRSC_con       129762   AA460273   Hs.12372   KIAA0517 protein   2.02   EB_cells, MB-MDA-435s, OVCAR_cells       120704   AA291970   Hs.107054   KIAA0821 protein   2.01   Lu_SC_H69, EB_cells, MB-MDA-453       105355   AA235985   Hs.26938   Human DNA seq from clone 126A5 on chromo   2.01   Lu_AD_H23, Lu_LC_H460, Lu_SQ_H520                   genes (one with DnaJ domains); the gene                   family member HKR3. Contains ESTs; STSs;       125952   AA017723       small inducible cytokine A5 (RANTES)   2.01   LNCaP_cells, DU145_cells, MB231_cells       103478   Y07755   Hs.38991   S100 calcium-binding protein A2   2.01   HMEC (total RNA), HMEC, RPWE_2       133544   T33873   Hs.74624   protein tyrosine phosphatase; receptor t   2.01   Lu_SC_H345, BT474_cells, HT29_cells       112746   R93237       yq11e10.s1 Soares fetal liver spleen 1NF   2.01   PC3_cells, LNCaP_cells, OVCAR_cells                   IMAGE: 196650 3′, mRNA seq.       118513   N67504   Hs.40061   ESTs   2.01   Lu_SC_H345, Lu_SC_H69, PRSC_con       123423   AA598484   Hs.238476   EST   2.01   EB_cells, Lu_AD_H23, Lu_SC_H345       127854   AA769520       ESTs; Weakly similar to REGULATOR OF MIT   2.01   HS578T_cells, CALU6_cells, Lu_SQ_H520       111843   R36969   Hs.18888   ESTs   2.01   Lu_AD_H23, Lu_AD_358, Lu_SQ_H520       100221   D28383       Human mRNA for ATP synthase B chain, 5′U   2.01   EB_cells, Lu_AD_H23, LNCaP_cells       129968   AA452237   Hs.194443   ESTs; Weakly similar to BC37295_2 [ H.sap     2.01   Lu_SC_H345, Lu_SC_H69, DU145_calls       106798   AA478968   Hs.20558   ESTs   2.01   EB_cells, Lu_AD_H23, Lu_LC_H460       114636   AA085374       zn13dS.s1 Stratagene hNT neuron (#937233   2.01   EB_cells, CALU6,_cells, OVCAR_cells                   gb:L8441 CYTOCHROME C OXIDASE   POLYPEPTI       125348   H21585   Hs.191277   ESTs; Moderately similar to ATP binding   2.01   EB_cells, HS578T_cells, PC3_cells       130620   AA233245   Hs.16773   ESTs   2.01   EB_cells, DU145_cells, 293T_cells       106471   AA450118   Hs.25722   ESTs; Weakly similar to ZINC FINGER PROT   2.01   OVCAR_cells, LNCaP_cells, EB_cells       134175   T33128   Hs.7966   ESTs   2   Lu_SC_H345, Fibroblasts 2, Lu_AD_H23       117291   N22289       yw36g08.s1 Morton Fetal Cochlea  H sapien     2   MB-MDA-453, OVCAR_cells, CALU6_cells       134199   U47635   Hs.79877   myotubularin related protein 6   2   EB_cells, PC3_cells, LNCaP_cells       128758   AA129545   Hs.181165   eukaryotic translation elongation factor   2   Lu_SC_H69, EB_cells, Lu_SC_H345       112005   R42569   Hs.22444   ESTs   2   Lu_AD_H23, PRSC_log, Lu_AD_358       122521   AA449433   Hs.149227   ESTs; Weakly similar to PROLINE-RICH PRO   2   HT29_cells, RPWE_2, MB231_cells       130368   X84373   Hs.155017   nuclear receptor interacting protein 1   2   DU145_cells, PC3_cells, MCF7       114067   Z38153   Hs.26921   ESTs   2   293T_cells, MB-MDA-435s, HT29_cells       107136   AA620795   Hs.8207   ESTs   2   LNCaP_cells, PC3_cells, EB_cells                    
     [0329]                           TABLE 3                                      Pkey:   Unique Eas probeset identifier number           ExAcon:   Exemplar Accession number, Genbank accession number           UnigeneID:   Unigene number           Unigene Title:   Unigene gene title                                                     Ratio           Pkey   Ex Accn   UG_ID   Complete_Title   BS/Met   Top 3 expressing cell lines                                             302347   AF039400   Hs.194059   chloride channel; calcium activated; fam   19.71   EB, NCI-H520, NCI-H23       316304   AI936587   Hs.221599   ESTs   14.49   PRSC_con, RPWE-2, OVCA-R       339196           CH22_FF113D11.GENSCAN.3-1   10.37   NCI-H69, PRSC_con, NCI-H345       336171           CH22_FGENES.708_3   9.45   NCI-H69, NCI-H460, NCI-H23       338895           CH22_DJ32I10.GENSCAN.9-2   9.31   PC3, BT474, OVCA-R       333625           CH22_FGENES.223_2   8.96   NCI-H69, PRSC_con, NCI-H345       333730           CH22_FGENES.258_1   8.82   NCI-H69, BT474, MB-MDA-231       320244   AA296922   Hs.129778   gastrointestinal peptide   8.22   BT474, CALU6, DU145       333643           CH22_FGENES.232_2   7.66   MCF7, NCI-H69, LnCap       333423           CH22_FGENES.147_3   7.57   HT29, MB-MDA-231, EB       302332   AI833168   Hs.184507     H sapiens  Chromosome 16 BAC clone CIT987   7.55   MB-MDA-231, HT29, MB-MDA-453       333588           CH22_FGENES.206_2   7.46   HT29, OVCA-R, BT474       322033   AL137507       EST cluster (not in UniGene)   7.35   PRSC_con, PRSC_log, NCI-H345       308601   AI719930       EST singleton (not in UniGene) with exon   6.83   PC3, DU145, DU145       339044           CH22_DA59H18.GENSCAN.27-5   6.46   NCI-H69, NCI-H345, PRSC_log       314516   AA371513   Hs.231748   ESTs   6.41   EB, OVCA-R, Caco2       327805           CH.05_hs gi|5867968   6.28   NCI-H69, NCI-H345, PRSC_con       334239           CH22_FGENES.364_2   6.09   NCI-H520, MB-MDA-435s, MB-MDA-453       332958           CH22_FGENES.48_15   6.04   NCI-H69, PRSC_con, PRSC_log       313386   W85772   Hs.173924   ESTs   5.88   MB-MDA-231, OVCA-R, BT474       314350   AL037927   Hs.190675   ESTs; Moderately similar to !!!! ALU SUB   5.84   OVCA-R, CALU6, EB       337170           CH22_FGENES.564-1   5.67   LnCap, CALU6, NCI-H69       337503           CH22_FGENES.803-1   5.66   NCI-H345, PRSC_con, RPWE-2       337562           CH22_C65E1.GENSCAN.1-2   5.53   HT29, MB-MDA-453, BT474       337219           CH22_FGENES.614-3   5.45   NCI-H69, NCI-H345, PRSC_log       311331   AI679622   Hs.32225   immunoglobulin alpha 1   5.43   NCI-H69, NCI-H23, NCI-H345       314251   AA713589       EST cluster (not in UniGene)   5.41   PC3, EB, LnCap       336246           CH22_FGENES.746_5   5.34   NCI-H69, NCI-H345, PRSC_log       335009           CH22_FGENES.472_13   5.31   ES, EB, NCI-H69       339365           CH22_BA354I12.GENSCAN.34-1   5.25   PRSC_con, NCI-H69, PRSC_log       336088           CH22_FGENES.688_17   5.21   PRSC_con, Caco2, PRSC_log       334966           CH22_FGENES.465_36   5.16   DU145, BT474, MB-MDA-231       334666           CH22_FGENES.418_18   5.15   NCI-H69, NCI-H345, PRSC_log       316830   AW182106   Hs.127821   ESTs   5.12   NCI-H345, PRSC_con, PRSC_log       339413           CH22_DJ579N16.GENSCAN.5-8   5.06   NCI-H69, NCI-H345, PRSC_log       337951           CH22_EM:AC005500.GENSCAN.94-1   5.01   NCI-H345, NCI-H69, PRSC_con       330153           CH21_p2 gi|4325335   5   PRSC_con, PRSC_log, NCI-H69       333987           CH22_FGENES.310_11   4.96   MB-MDA-231, MB-MDA-453, MB-MDA-453       334304           CH22_FGENES.373_7   4.96   OVCA-R, CALU6, NCI-H23       338990           CH22.DA59H18.GENSCAN.6-6   4.95   PRSC_log, PRSC_con, NCI-H69       333152           CH22_FGENES.89_1   4.89   MB-MDA-435s, OVCA-R, A549       327049           CH.21_hs gi|6531965   4.87   PRSC_con, NCI-H345, PRSC_log       337225           CH22_FGENES.626-3   4.83   DU145, CALU6, EB       333496           CH22_FGENES.168_6   4.81   NCI-H69, NCI-H345, PRSC_con       334451           CH22_FGENES.387_11   4.79   RPWE-2, PRSC_con, NCI-H69       333594           CH22_FGENES.210_3   4.78   OVCA-R, PC3, HT29       333635           CH22_FGENES.228_2   4.78   NCI-H69, PRSC_log, PRSC_con       336796           CH22.FGENES.176-6   4.73   NCI-H69, NCI-H345, PRSC_log       333313           CH22_FGENES.138_5   4.72   NCI-H69, NCI-H345, PRSC_log       336833           CH22_FGENES.242-2   4.7   NCI-H345, NCI-H69, PRSC_con       336090           CH22_FGENES.689_2   4.7   NCI-H69, PRSC_con, PRSC_log       336645           CH22_FGENES.26-1   4.63   HT29, OVCA-R, DU145       334565           CH22_FGENES.405_5   4.62   NCI-H345, PRSC_log, RPWE-2       333242           CH22_FGENES.111_6   4.56   NCI-H345, PRSC_log, PRSC_con       326304           CH.17_hs gi|5867277   4.48   OVCA-R, EB, DU145       337445           CH22_FGENES.769-4   4.47   RPWE-2, NCI-H69, PRSC_log       327413           CH.02_hs gi|5867750   4.46   NCI-H69, PRSC_log, NCI-H345       327990           CH.06_hs gi|5868218   4.44   PRSC_con, PRSC_log, RPWE-2       325038   H38304   Hs.21782   ESTs   4.43   PRSC_con, MB-MDA-231, HT29       314923   AI732489   Hs.136370   ESTs   4.4   HT29, MB-MDA-231, NCI-358       328859           CH.07_hs gi|6381928   4.4   OVCA-R, BT474, A549       334476           CH22_FGENES.394_7   4.38   OVCA-R, PC3, EB       336092           CH22_FGENES.689_6   4.35   PRSC_con, Caco2, PRSC_log       333965           CH22_FGENES.305_3   4.35   NCI-H69, NCI-H345, PRSC_log       336402           CH22.FGENES.823_17   4.34   RPWE-2, HT29, OVCA-R       337947           CH22_EM:AC005500.GENSCAN.90-5   4.33   OVCA-R, DU145, PC3       337504           CH22_FGENES.803-2   4.33   NCI-H345, PRSC_con, PRSC_log       336813           CH22_FGENES.213-6   4.33   DU145, HT29, OVCA-R       338069           CH22_EM:AC005500.GENSCAN.166-14   4.33   NCI-H69, PRSC_con, NCI-H345       318538   N28625   Hs.74034   caveolin 1; caveolae protein; 22 kD   4.31   PC3, A549, BT474       333631           CH22_FGENES.227_2   4.3   OVCA-R, PRSC_con, LnCap       302646   M14268       EST   4.27   PRSC_con, PRSC_log, RPWE-2       336049           CH22.FGENES.681_2   4.26   HT29, DU145, DU145       335667           CH22_FGENES.590_18   4.25   NCI-H520, Caco2, MB-MDA-453       320352   Y13323   Hs.145296   disintegrin protease   4.25   MB-MDA-231, DU145, BT474       304480   AA430373       EST singleton (not in UniGene) with exon   4.22   NCI-358, NCI-H460, NCI-H23       327273           CH.01_hs gi|5867466   4.22   NCI-H69, NCI-H345, PRSC_con       334540           CH22FGENES.403_5   4.17   NCI-H69, NCI-H345, PRSC_log       334719           CH22_FGENES.421_30   4.17   NCI-H69, NCI-H345, RPWE-2       327827           CH.05_hs gi|5867968   4.17   OVCA-R, NCI-H69, CALU6       333599           CH22_FGENES.212_2   4.17   PRSC_log, NCI-H69, PRSC_con       329638           CH.12_p2 gi|3779004   4.16   DU145, MB-MDA-231, HT29       307556   AI281651       EST singleton (not in UniGene) with exon   4.16   BT474, HT29, CALU6       336836           CH22_FGENES.247-11   4.15   PRSC_con, NCI-H345, NCI-H69       323187   AL121180   Hs.240038   ESTs   4.14   NCI-H345, MB-MDA-435s, RPWE-2       336397           CH22_FGENES.823.12   4.13   NCI-H345, PRSC_con, RPWE-2       325007   AA736429       EST cluster (not in UniGene)   4.13   NCI-H69, PRSC_con, NCI-H345       300199   AI304386   Hs.150836   ESTs   4.11   NCI-H345, PRSC_con, PRSC_log       335832           CH22_FGENES.620_6   4.08   NCI-H69, NCI-H345, PRSC_log       312778   AI631655   Hs.197919   ESTs   4.07   NCI-358, NCI-H23, PRSC_con       323154   AA765301   Hs.151858   ESTs   4.06   NCI-H23, A549, HT29       315871   AW135312   Hs.117237   ESTs   4.05   MB-MDA-231, EB, MCF7       337452           CH22_FGENES.775-1   4.02   PRSC_con, PRSC_log, NCI-H345       335265           CH22_FGENES.521_1   4.01   NCI-H69, MCF7, RPWE-2       335200           CH22_FGENES.508_9   4.01   NCI-H69, PRSC_log, PRSC_con       336917           CH22_FGENES.346-4   3.99   PRSC_con, NCI-H345, PRSC_log       336584           CH22_FGENES.847_1   3.98   PRSC_log, PRSC_con, RPWE-2       333382           CH22_FGENES.143_21   3.97   EB, A549, HT29       329436           CH.Y_hs gi|5868883   3.97   BT474, PC3, HT29       336929           CH22_FGENES.349-3   3.94   NCI-H69, NCI-H345, PRSC_log       337238           CH22.FGENES.641-3   3.92   NCI-H69, NCI-H345, PRSC_log       333875           CH22.FGENES.291_11   3.92   PRSC_con, RPWE-2, PRSC_log       337069           CH22_FGENES.448.2   3.9   NCI-H69, LnCap, RPWE-2       332491   M24470   Hs.1435   guanosine monophosphate reductase   3.86   OVCA-R, MB-MDA-435s, CALU6       304623   AA521331       EST singleton (not in UniGene) with exon   3.86   OVCA-R, DU145, PC3       335348           CH22_FGENES.537_4   3.85   HT29, MB-MDA-231, PC3       334568           CH22_FGENES.405_9   3.85   NCI-H69, NCI-H345, PRSC_log       336924           CH22.FGENES.347-9   3.84   NCI-H345, PRSC_log, RPWE-2       301654   H81795       EST   3.84   NCI-H520, LnCap, NCI-358       334677           CH22_FGENES.418_30   3.83   PRSC_con, NCI-H345, NCI-H69       326688           CH.20.hs gi|5867582   3.83   NCI-H345, PRSC_con, PRSC_log       327790           CH.05_hs gi|5867977   3.8   PRSC_con, PRSC_log, NCI-H345       334591           CH22_FGENES.408_1   3.8   NCI-H69, PRSC_log, NCI-H345       337974           CH22_EM:AC005500.GENSCAN.106-3   3.78   PRSC_log, PRSC_con, NCI-H345       311274   AW293128   Hs.197101   ESTs   3.78   NCI-H345, PRSC_con, RPWE-2       326668           CH.20_hs gi|6552455   3.78   NCI-H345, NCI-H69, PRSC_log       304195   N35382       EST singleton (not in UniGene) with exon   3.77   NCI-H69, RPWE-2, PRSC_con       336294           CH22_FGENES.786_4   3.77   PRSC_con, PRSC_log, NCI-H69       311613   AL046311   Hs.252443   ESTs; Weakly similar to !!!! ALU SUBFAMI   3.76   HT29, BT474, MB-MDA-231       338123           CH22_EM:AC005500.GENSCAN.195-5   3.75   MB-MDA-231, HT29, BT474       318230   AA558125       EST cluster (not in UniGene)   3.74   RPWE-2, PRSC_con, NCI-H345       303985   AW514501   Hs.156110   Immunoglobulin kappa variable 1D-8   3.73   MB-MDA-231, BT474, PRSC_con       336502           CH22_FGENES.833_8   3.72   NCI-H345, RPWE-2, PRSC_con       334063           CH22_FGENES.327_17   3.71   NCI-H69, NCI-H345, PRSC_con       333600           CH22_FGENES.213_2   3.7   NCI-H69, OVCA-R, PC3       339424           CH22_DJ579N16.GENSCAN.14-3   3.69   NCI-H69, NCI-H345, PRSC_con       336862           CH22_FGENES.297-2   3.67   NCI-H345, PRSC_con, PRSC_log       334823           CH22.FGENES.437_5   3.67   RPWE-2, PRSC_log, PRSC_con       329940           CH.16_p2 gi|6165199   3.66   CALU6, EB, MCF7       300275   A1632123   Hs.231521   ESTs   3.66   PRSC_con, NCI-H69, RPWE-2       328820           CH.07_hs gi|5868330   3.66   NCI-H69, NCI-H345, PRSC_con       332398   AA446446   Hs.104788     H sapiens  clone 24554 unknown mRNA   3.66   PRSC_con, PRSC_log, NCI-H345       325791           CH.14_hs gi|6682476   3.65   NCI-H345, BT474, LnCap       300672   R14469   Hs.258573   ESTs   3.65   MCF7, MB-MDA-453, MB-MDA-435s       338344           CH22_EM:AC005500.GENSCAN.312-8   3.65   NCI-H345, PRSC_log, PRSC_con       333257           CH22_FGENES.118_5   3.65   DU145, EB, OVCA-R       332140   AA620724   Hs.112890   ESTs   3.65   MB-MDA-453, DU145, MCF7       337489           CH22_FGENES.799-2   3.63   NCI-H345, NCI-H69, PRSC_log       305167   AA663080       EST singleton (not in UniGene) with exon   3.63   OVCA-R, MB-MDA-231, MB-MDA-435s       336200           CH22_FGENES.719_4   3.61   NCI-H69, PRSC_log, NCI-H345       339208           CH22_FF113D11.GENSCAN,6-3   3.59   PRSC_con, NCI-H69, PRSC_log       320090   AB002058   Hs.113275   purinergic receptor P2X-Iike 1; orphan r   3.58   OVCA-R, LnCap, NCI-H69       335999           CH22_FGENES.657_1   3.57   NCI-H345, NCI-H69, PRSC_con       332909           CH22_FGENES.36_13   3.57   NCI-H345, PRSC_con, PRSC_log       306531   AA991423       EST singleton (not in UniGene) with exon   3.56   BT474, MB-MDA-453, MB-MDA-435s       333261           CH22_FGENES.119_1   3.55   HT29, CALU6, MB-MDA-231       303883   AA176396   Hs.169624   ESTs   3.54   NCI-H69, NCI-H345, RPWE-2       335831           CH22_FGENES.620_5   3.53   MCF7, BT474, OVCA-R       333983           CH22_FGENES.310_7   3.52   NCI-H345, PRSC_con, PRSC_log       333623           CH22_FGENES.222_2   3.51   NCI-H69, PRSC_con, PRSC_log       333997           CH22_FGENES.310_22   3.5   NCI-H345, PRSC_con, PRSC_log       325623           CH.14_hs gi|5867000   3.5   CALU6, HT29, BT474       309151   AI935829   Hs.140   immunoglobulin gamma 3 (Gm marker)   3.49   EB, MCF7, MB-MDA-453       305080   AA641485       EST singleton (not in UniGene) with exon   3.49   NCI-H23, NCI-H460, NCI-358       339268           CH22_BA354I12.GENSCAN.10-6   3.47   NCI-H69, NCI-H345, PRSC_con       310048   AI198352   Hs.105077   ESTs   3.47   Caco2, PRSC_con, NCI-H69       314758   AA521458   Hs.192738   ESTs   3.46   NCI-H23, NCI-H23, NCI-H520       334664           CH22_FGENES.418_15   3.45   NCI-H69, PRSC_log, PRSC_con       334661           CH22_FGENES.418_9   3.45   NCI-H69, PRSC_con, PRSC_log       330984   H38678   Hs.32766     H sapiens  clone 24803 mRNA seq   3.44   OVCA-R, MCF7, PC3       333464           CH22_FGENES.160_1   3.44   NCI-H69, MB-MDA-231, MCF7       333580           CH22_FGENES.199_2   3.42   PRSC_con, NCI-H69, PRSC_log       313356   AI266254   Hs.132929   ESTs   3.42   RPWE-2, PRSC_con, NCI-H345       334518           CH22_FGENES.400_1   3.41   PRSC_log, PRSC_con, RPWE-2       333627           CH22_FGENES.225_2   3.4   HT29, BT474, BT474       309641   AW194230   Hs.253100   EST   3.4   HT29, MB-MDA-453, MCF7       338221           CH22_EM:AC005500.GENSCAN.246-10   3.4   NCI-H69, PRSC_log, NCI-H345       312993   AI392673   Hs.125230   ESTs   3.4   PRSC_log, NCI-H345, NCI-H345       318336   AI971806   Hs.164158   ESTs   3.38   OVCA-R, ES, CALU6       326218           CH.17_hs gi|5867226   3.38   NCI-H460, NCI-H69, NCI-H345       336231           CH22_FGENES.736_3   3.38   NCI-H69, NCI-H345, PRSC_log       307912   AI382224       EST singleton (not in UniGene) with exon   3.37   NCI-H345, PRSC_con, RPWE-2       336161           CH22FGENES.707_6   3.37   NCI-H69, NCI-H345, RPWE-2       300875   AW134756   Hs.192477   ESTs   3.37   RPWE-2, PRSC_log, PRSC_con       336593           CH22_FGENES.135_1   3.37   PRSC_con, NCI-H69, RPWE-2       310696   AI431620   Hs.160875   ESTs   3.36   HT29, OVCA-R, BT474       304745   AA577771       EST singleton (not in UniGene) with exon   3.36   NCI-H345, RPWE-2, PRSC_con       308911   AI860287   Hs.156110   Immunoglobulin kappa variable 1D-8   3.36   EB, DU145, CALU6       336347           CH22.FGENES.815_3   3.36   NCI-H69, PRSC_log, PRSC_con       334906           CH22_FGENES.452_21   3.33   Caco2, CALU6, MB-MDA-453       334548           CH22_FGENES.403_13   3.33   NCI-H345, PRSC_con, NCI-H69       336695           CH22_FGENES.48-4   3.32   NCI-H69, PRSC_log, PRSC_con       316684   AA807187   Hs.220783   ESTs; Weakly similar to WNT-1 PROTO-ONCO   3.31   DU145, ES, MB-MDA-231       315901   AI521558   Hs.179718   v-myb avian myeloblastosis viral oncogen   3.3   Caco2, LnCap, NCI-H69       320115   T93574       EST cluster (not in UniGene)   3.3   DU145, HT29, CALU6       307847   AI363993   Hs.157273   EST   3.3   NCI-H345, PRSC_con, PRSC_log       327899           CH.06_hs gi|5868156   3.28   BT474, MB-MDA-231, A549       304612   AA514207       EST singleton (not in UniGene) with exon   3.28   DU145, CALU6, LnCap       330021           CH.16_p2 gi|6671889   3.27   A549, HT29, EB       338132           CH22_EM:AC005500.GENSCAN.200-2   3.27   MB-MDA-231, CALU6, EB       323690   AA317497   Hs.188897   ESTs   3.27   RPWE-2, NCI-H345, MCF7       327362           CH.01_hs gi|6552412   3.26   NCI-H69, RPWE-2, PRSC_log       333488           CH22.FGENES.167_3   3.26   NCI-H69, NCI-H345, PRSC_log       334106           CH22_FGENES.330_5   3.26   NCI-H69, PRSC_con, PRSC_log       306990   AI129298   Hs.146491   EST; Weakly similar to FERRITIN HEAVY CH   3.26   NCI-H345, PRSC_log, PRSC_con       328420           CH.07_hs gi|5868411   3.26   NCI-H69, NCI-H345, PRSC_log       336214           CH22_FGENES.722_8   3.26   MCF7, ES, OVCA-R       330565   U51095   Hs.1545   caudal type homeo box transcription fact   3.25   EB, DU145, HT29       333879           CH22_FGENES.291_15   3.25   PRSC_con, PRSC_log, NCI-H69       300145   AI240850   Hs.232016   ESTs   3.25   NCI-H345, PRSC_con, PRSC_log       327581           CH.03_hs gi|5867825   3.25   EB, DU145, MB-MDA-453       308153   AI500429   Hs.1103   transforming growth factor; beta 1   3.24   MCF7, EB, EB       308337   AI608947       EST singleton (not in UniGene) with exon   3.24   PRSC_log, PRSC_con, NCI-H345       329406           CH.X_hs gi|6682547   3.23   DU145, HT29, MB-MDA-231       325482           CH.12_hs gi|5866957   3.23   NCI-H69, NCI-H345, PRSC_con       337544           CH22_FGENES.833-7   3.22   NCI-H69, NCI-H345, PRSC_con       337204           CH22_FGENES.595-1   3.22   NCI-H69, PRSC_con, PRSC_log       309451   AW105128   Hs.246687   EST   3.22   PRSC_con, RPWE-2, NCI-H345       337259           CH22_FGENES.649-3   3.2   PRSC_con, NCI-H345, NCI-H69       336489           CH22_FGENES.831_10   3.2   CALU6, MB-MDA-435s, Caco2       334804           CH22_FGENES.435_4   3.18   PRSC_log, PRSC_con, RPWE-2       335739           CH22_FGENES.601_10   3.18   NCI-H69, RPWE-2, PRSC_con       306264   AA935305   Hs.179779   ribosomal protein L37   3.17   LnCap, NCI-H69, EB       329386           CH.X_hs gi|6004484   3.17   RPWE-2, NCI-H345, PRSC_log       323479   AA278246       EST cluster (not in UniGene)   3.16   PRSC_con, NCI-H345, RPWE-2       304731   AA576085       EST singleton (not in UniGene) with exon   3.16   NCI-H69, LnCap, DU145       339419           CH22_DJ579N16.GENSCAN.11-11   3.15   NCI-H69, PRSC_log, RPWE-2       301202   AI536797   Hs.173155   ESTs   3.15   LnCap, NCI-H69, Caco2       333608           CH22_FGENES.216_3   3.15   NCI-H345, PRSC_con, PRSC_log       339193           CH22_FF113D11.GENSCAN.1-5   3.14   NCI-H69, NCI-H345, PRSC_con       310527   AW293404   Hs.211986   ESTs   3.14   PRSC_log, PRSC_con, RPWE-2       321146   AA707443   Hs.183983   ESTs   3.14   PRSC_con, NCI-H69, PRSC_log       333271           CH22_FGENES.121_2   3.13   NCI-H345, NCI-H69, RPWE-2       330280           CH.05_p2 gi|6671910   3.13   NCI-H69, NCI-H345, PRSC_log       309977   AW451663       EST singleton (not in UniGene) with exon   3.13   PRSC_con, PRSC_log, RPWE-2       307588   AI285535       EST singleton (not in UniGene) with exon   3.13   MB-MDA-231, BT474, BT474       330551   U39840   Hs.105440   hepatocyte nuclear factor 3; alpha   3.13   MB.MDA-453, LnCap, Caco2       314404   AW104203   Hs.157505   ESTs   3.13   DU145, EB, OVCA-R       334030           CH22_FGENES.320_2   3.13   NCI-H69, NCI-H345, PRSC_con       309108   AI925949       EST singleton (not in UniGene) with exon   3.13   BT474, MCF7, EB       317516   AI733250   Hs.192262   ESTs   3.12   OVCA-R, EB, MB-MDA-453       304161   H71886       EST singleton (not in UniGene) with exon   3.12   PRSC_con, NCI-H69, RPWE-2       334590           CH22_FGENES.407_13   3.12   NCI-H69, NCI-H345, PRSC_con       333408           CH22_FGENES.145_6   3.11   PRSC_log, RPWE-2, PRSC_con       330387   H14624   Hs.31386   ESTs; Highly similar to secreted apoptos   3.11   DU145, OVCA-R, PC3       332567   N23730   Hs.25647   v-fos FBJ murine osteosarcoma viral onco   3.11   EB, MB-MDA-453, MCF7       333682           CH22_FGENES.247_10   3.1   PRSC_con, PRSC_log, RPWE-2       323152   AI680562   Hs.246192   ESTs; Weakly similar to REGULATOR OF MIT   3.1   PC3, MB-MDA-453, DU145       311142   AI638441   Hs.195649   ESTs   3.1   PRSC_con, RPWE-2, PRSC_log       333441           CH22_FGENES.151_5   3.1   RPWE-2, NCI-H345, PRSC_log       326459           CH.19_hs gi|5867400   3.09   EB, CALU6, PC3       313493   AA910339   Hs.126868   ESTs   3.09   NCI-H345, PRSC_con, RPWE-2       339356           CH22_SA354I12.GENSCAN.31-1   3.08   NCI-H69, NCI-H345, PRSC_log       333629           CH22_FGENES.226_5   3.08   NCI-H69, NCI-H345, PRSC_log       304127   H42981       EST singleton (not in UniGene) with exon   3.07   LnCap, PRSC_con, DU145       325691           CH.14_hs gi|5867021   3.07   NCI-H345, PRSC_con, NCI-H69       333014           CH22_FGENES.61_6   3.07   PRSC_con, PRSC_log, NCI-H345       327379           CH.02_hs gi|5867795   3.07   PRSC_con, PRSC_log, NCI-H69       337816           CH22_EM:AC005500.GENSCAN.13-1   3.06   NCI-H69, PRSC_con, PRSC_log       337954           CH22_EM:AC005500.GENSCAN.96-3   3.06   PRSC_log, NCI-H69, NCI-H345       328109           CH.06_hs gi|5868020   3.05   HT29, BT474, MB-MDA-231       338527           CH22_EM:AC005500.GENSCAN.396-15   3.05   NCI-H69, NCI-H345, PRSC_con       320083   T87761       EST duster (not in UniGene)   3.05   BT474, MS-MDA-435s, MCF7       333486           CH22_FGENES.161_2   3.05   NCI-H345, RPWE-2, PRSC_log       334788           CH22.FGENES.432_13   3.04   EB, A549, CALU6       302681   X97550       EST   3.04   OVCA-R, EB, MB-MDA-453       336238           CH22_FGENES.743_3   3.03   NCI-H69, PRSC_log, PRSC_con       337606           CH22_C20H12.GENSCAN.17-2   3.02   HT29, BT474, MS-MDA-231       333545           CH22_FGENES.180_1   3.02   NCI-H69, NCI-H345, RPWE-2       309782   AW275156   Hs.156110   Immunoglobulin kappa variable 1D-8   3.02   PRSC_log, PRSC_con, RPWE-2       324277   AA429440   Hs.207285   ESTs   3.02   BT474, MB-MDA-231, HT29       321074   H38098   Hs.32756   ESTs   3.02   PC3, BT474, MB-MDA-231       337094           CH22_FGENES.465-19   3.01   PRSC_con, PRSC_log, RPWE-2       313913   AW391342       EST cluster (not in UniGene)   3   NCI-H345, RPWE-2, PRSC_log       329140           CH.X_hs gi|6017060   3   EB, DU145, PC3       335331           CH22.FGENES.535_4   3   MS-MDA-435s, HT29, BT474       334827           CH22_FGENES.437_9   2.99   CALU6, EB, DU145       326029           CH.17_hs gi|5867176   2.99   NCI-H345, RPWE-2, PRSC_con       303100   T09353       EST   2.99   MS-MDA-453, NCI-H345, RPWE-2       328768           CH.07_hs gi|6017031   2.99   NCI-H345, PRSC_con, NCI-H69       329392           CH.X_hs gi|6478815   2.98   NCI-H69, NCI-H345, PRSC_con       305168   AA663105       EST singleton (not in UniGene) with exon   2.98   LnCap, NCI-H345, MCF7       300992   AA601213   Hs.191798   ESTs   2.98   Caco2, HT29, NCI-358       334474           CH22_FGENES.394_5   2.98   NCI-H69, PRSC_con, RPWE-2       322647   AA007534   Hs.125062   ESTs   2.98   HT29, OVCA-R, A549       310620   AI341328   Hs.178953   ESTs   2.97   PRSC_con, RPWE-2, PRSC_log       328276           CH.07_hs gi|6004471   2.97   NCI-H345, NCI-H69, RPWE-2       331018   N26904   Hs.24048   ESTs; Weakly similar to FK506/rapamycin-   2.96   Caco2, NCI-H60, A549       321523   H78472   Hs.191325   ESTs; Weakly similar to cDNA EST yk414c9   2.96   PRSC_con, PRSC_log, NCI-H345       339280           CH22_BA354I12,GENSCAN.14-12   2.96   NCI-H69, PRSC_log, NCI-H345       305967   AA886428       EST singleton (not in UniGene) with exon   2.96   NCI-H520, NCI-358, MS-MDA-453       335755           CH22_FGENES.604_4   2.95   EB, A549, MB-MDA-453       323907   AL043098   Hs.165387   ESTs   2.95   PRSC_con, NCI-H345, PRSC_log       330370           CH.X_p2 gi|6580495   2.95   EB, DU145, MB-MDA-435s       334529           CH22_FGENES.402_9   2.94   EB, MCF7, DU145       339256           CH22_BA354I12.GENSCAN.7-11   2.94   NCI-H69, NCI-H345, PRSC_con       334783           CH22_FGENES.432_8   2.94   A549, Caco2, PC3       335266           CH22_FGENES.521_2   2.94   NCI-H69, PRSC_con, PRSC_con       323707   AA845957   Hs.128385   ESTs   2.94   NCI-H345, PRSC_con, PRSC_log       336199           CH22_FGENES.719_3   2.93   NCI-H69, NCI-H345, PRSC_log       338326           CH22_EM:AC005500.GENSCAN.308-2   2.93   NCI-H69, NCI-H345, NCI-358       333652           CH22_FGENES.239_1   2.93   PC3, OVCA-R, BT474       336479           CH22.FGENES.829_39   2.92   NCI-H69, PRSC_con, PRSC_log       336086           CH22_FGENES.688_15   2.92   PRSC_con, Caco2, CALU6       338516           CH22.EM:AC005500.GENSCAN.392-6   2.92   NCI-H69, NCI-H345, PRSC_con       320121   T93657       EST cluster (not in UrnGene)   2.92   EB, BT474, HT29       305782   AA844730       EST singleton (not in UniGene) with exon   2.92   MB-MDA-453, MCF7, DU145       339304           CH22_BA354I12.GENSCAN.20-16   2.91   PRSC_con, PRSC_log, NCI-H69       327472           CH.02_hs gi|5867775   2.91   PRSC_log, PRSC_con, RPWE-2       311458   AW139426   Hs.244718   ESTs   2.91   PRSC_con, PRSC_log, RPWE-2       338431           CH22_EM:AC005500.GENSCAN.351-4   2.9   BT474, MCF7, MB-MDA-453       339230           CH22_BA354I12.GENSCAN.1-6   2.89   NCI-H69, NCI-H345, PRSC_log       320588   NM_00365       EST cluster (not in UniGene)   2.89   OVCA-R, HT29, MB-MDA-231       304777   AA581692   Hs.2186   eukaryotic translation elongation factor   2.89   OVCA-R, EB, MCF7       337768           CH22_EM:AC000097.GENSCAN.119-6   2.88   NCI-H69, LnCap, DU145       319465   AA319115   Hs.191558   ESTs   2.88   NCI-H460, NCI-H520, NCI-358       319068   W93011   Hs.110155   ESTs   2.87   BT474, MB-MDA-453, MB-MDA-435s       330958   H08815   Hs.159824   EST   2.87   OVCA-R, PC3, A549       334215           CH22_FGENES.357_7   2.87   NCI-H69, PRSC_con, PRSC_log       333568           CH22_FGENES.185_1   2.87   PRSC_con, PRSC_log, NCI-H69       333142           CH22_FGENES.85_5   2.87   NCI-H69, HT29, HT29       330239           CH.05_p2 gi|6671857   2.87   MB-MDA-453, MB-MDA-453, EB       302120   R55140   Hs.31075   ESTs; Weakly similar to Weak similarity   2.87   CALU6, MB-MDA-435s, BT474       338679           CH22_EMAC005500.GENSCAN.470-1   2.86   NCI-H345, PRSC_log, PRSC_con       329041           CH.X_hs gi|5868564   2.86   LnCap, PRSC_con, RPWE-2       333541           CH22_FGENES.178_3   2.86   NCI-H69, NCI-H345, PRSC_con       337011           CH22_FGENES.427-6   2.86   NCI-H69, PRSC_log, PRSC_con       324031   AA375646       EST cluster (not in UniGene)   2.86   NCI-H345, PRSC_log, LnCap       331842   AA416586   Hs.98232   ESTs   2.86   DU145, OVCA-R, HT29       336599           CH22_FGENES.350_3   2.85   LnCap, NCI-H69, NCI-H345       337586           CH22_C20H12.GENSCAN.5-4   2.85   NCI-H345, NCI-H69, PRSC_con       336177           CH22_FGENES.712_2   2.85   NCI-H69, PRSC_log, RPWE-2       337522           CH22_FGENES.819-1   2.85   CALU6, OVCA-R, HT29       338598           CH22_EM:AC005500.GENSCAN.437-2   2.85   NCI-H69, PRSC_con, NCI-H345       309522   AW150044   Hs.252259   ribosomal protein S3   2.85   MB-MDA-453, MB-MDA-435s, MB-MDA-435s       336981           CH22_FGENES.397-7   2.85   NCI-H69, PRSC_con, PRSC_log       330286           CH.05_p2 gi|6671913   2.84   NCI-H345, PRSC_log, NCI-H69       333713           CH22_FGENES.251_2   2.84   RPWE-2, PRSC_con, NCI-H69       335068           CH22_FGENES.483_5   2.83   MB-MDA-231, NCI-H345, RPWE-2       305075   AA641288   Hs.181165   eukaryotic translation elongation factor   2.83   EB, LnCap, DU145       326380           CH.19_hs gi|5867327   2.82   NCI-H69, PRSC_con, PRSC_log       334970           CH22_FGENES.466_3   2.82   PRSC_con, NCI-H69, RPWE-2       337097           CH22_FGENES.471-1   2.82   NCI-H345, NCI-H69, PRSC_log       323676   AI702835       EST cluster (not in UniGene)   2.82   LnCap, A549, CALU6       333785           CH22.FGENES.274_4   2.82   OVCA-R, Caco2, MB-MDA-453       334175           CH22.FGENES.349_10   2.81   RPWE-2, BT474, MCF7       337865           CH22_EM:AC005500.GENSCAN.46-5   2.81   Caco2, NCI-H23, BT474       302585   AA083564   Hs.249220     H sapiens  mRNA for hTbr2; complete cds   2.81   EB, DU145, MB-MDA-453       336623           CH22_FGENES.4-5   2.81   NCI-H345, PRSC_con, NCI-H69       332854           CH22.FGENES.22_1   2.8   RPWE-2, PRSC_log, PRSC_con       336978           CH22.FGENES.384-10   2.8   PRSC_con, NCI-H345, RPWE-2       326874           CH.20_hs gi|6682507   2.8   RPWE-2, NCI-H345, PRSC_log       315121   AA585011   Hs.105902   ESTs   2.8   NCI-H345, PRSC_log, RPWE-2       311185   AI638294   Hs.224665   ESTs   2.8   NCI-H69, NCI-H345, PRSC_log       334682           CH22_FGENES.419_4   2.8   NCI-H69, PRSC_log, RPWE-2       316845   AW418715   Hs.250388   ESTs   2.79   RPWE-2, NCI-H345, PRSC_log       331599   N74826   Hs.50535   ESTs   2.79   A549, MB-MDA-453, MB-MDA-435s       315681   AW022054   Hs.136591   ESTs   2.78   NCI-H460, MB-MDA-453, MCF7       313012   AI207390   Hs.143929   ESTs   2.78   DU145, MS-MDA-453, MCF7       313476   AA010267       EST cluster (not in UniGene)   2.78   NCI-H520, NCI-H460, HT29       327277           CH.01_hs gi|5867473   2.78   DU145, CALU6, EB       310981   AI494514   Hs.171380   ESTs   2.78   LnCap, RPWE-2, NCI-H460       335090           CH22.FGENES.490_1   2.77   NCI-H69, PRSC_log, PRSC_con       328581           CH.07.hs gi|6006033   2.77   HT29, MB-MDA-453, MCF7       333219           CH22_FGENES.104_11   2.77   NCI-H69, PRSC_log, NCI-H345       308311   AI581855       EST singleton (not in UniGene) with exon   2.77   MB-MDA-231, HT29, CALU6       329760           CH.14_p2 gi|6048280   2.77   CALU6, DU145, ES       303925   AW469999   Hs.258523   ESTs   2.77   NCI-H69, LnCap, MS-MDA-231       337628           CH22_C20H12.GENSCAN.28-31   2.77   NCI-H69, LnCap, MB-MDA-453       333520           CH22_FGENES.174_3   2.77   NCI-H69, NCI-H345, PRSC_con       303168   AA872479   Hs.197770   ESTs; Weakly similar to estrogen-respons   2.76   DU145, OVCA-R, MB-MDA-453       313451   AW138189   Hs.122672   ESTs   2.76   OVCA-R, EB, DU145       328474           CH.07_hs gi|5868446   2.76   NCI-H69, NCI-H345, RPWE-2       331988   AA477414   Hs.9242   purine-rich element binding protein B   2.76   MB-MDA-435s, A549, OVCA-R       306180   AA922503       EST singleton (not in UniGene) with exon   2.76   NCI-H69, DU145, LnCap       321071   AA013011   Hs.241502   Cdc42 effector protein 4   2.76   PRSC_log, PRSC_con, NCI-H345       302972   W73400       EST   2.76   NCI-H345, RPWE-2, NCI-H69       305185   AA663985   Hs.248038   major histocompatibility complex; class   2.75   DU145, A549, BT474       335998           CH22_FGENES.656_16   2.75   NCI-H69, PRSC_con, RPWE-2       319138   R11699   Hs.73818   ubiquinol-cytochrome c reductase hinge p   2.75   NCI-H345, NCI-H69, PRSC_con       336387           CH22_FGENES.822_7   2.75   PRSC_con, RPWE-2, PRSC_log       338054           CH22.EM:AC005500.GENSCAN.158-2   2.75   OVCA-R, EB, DU145       316041   AA719183       EST duster (not in UniGene)   2.74   DU145, MCF7, MB-MDA-453       336863           CH22_FGENES.297-4   2.74   MB-MDA-453, MCF7, OVCA-R       335975           CH22_FGENES.652_9   2.74   CALU6, EB, A549       302952   AF103179       EST   2.74   CALU6, MB.MDA-435s, BT474       326122           CH.17_hs gi|5867194   2.74   HT29, Caco2, PC3       337427           CH22_FGENES.761-4   2.74   RPWE-2, NCI-H89, PRSC_log       308063   AI469244   Hs.119252   tumor protein; translationally-controlle   2.74   NCI-358, NCI-H23, Caco2       325433           CH.12_hs gi|5866936   2.74   NCI-H345, PRSC_con, RPWE-2       316252   AI572633   Hs.190406   ESTs   2.74   OVCA-R, MCF7, A549       310837   AI418688   Hs.170301   ESTs   2.74   NCI-H345, PRSC_con, RPWE-2       313562   AW467335   Hs.257676   ESTs   2.74   HT29, MCF7, MB-MDA-231       335455           CH22_FGENES.562_15   2.74   NCI-H69, LnCap, PRSC_con       304792   AA583101   Hs.29797   ribosomal protein L10   2.73   EB, OVCA-R, MB-MDA-453       331979   AA469937   Hs.105322   EST   2.73   MCF7, BT474, NCI-H460       336198           CH22_PGENES.719_2   2.73   NCI-H69, PRSC_con, PRSC_log       314698   AI660452   Hs.187127   ESTs   2.73   MB-MDA-231, LnCap, BT474       307954   AI419692       EST singleton (not in UniGene) with exon   2.73   HT29, HT29, EB       318288   AI088590   Hs.134702   ESTs   2.73   PRSC_log, NCI-H345, PRSC_con       327833           CH.05_hs gi|5867968   2.73   BT474, PC3, MB-MDA-231       300221   AW449602   Hs.217953   ESTs; Highly similar to NK-TUMOR RECOGNI   2.73   NCI-H520, NCI-358, MB-MDA-453       326039           CH.17_hs gi|5867179   2.73   MB-MDA-453, EB, ES       318457   AI149678   Hs.143952   ESTs   2.72   PRSC_con, PRSC_log, NCI-H345       336753           CH22_FGENES.128-9   2.72   MB-MDA-435s, NCI-H520, MCF7       330086           CH.194_p2 gi|6015293   2.72   HT29, MB-MDA-453, MCF7       333566           CH22_FGENES.183_2   2.72   HT29, BT474, OVCA-R       339384           CH22_BA232E17.GENSCAN.3-22   2.71   NCI-H69, NCI-H345, PRSC_log       338668           CH22_EMAC005500.GENSCAN.465-1   2.71   NCI-H69, RPWE-2, PRSC_con       300798   AI382618   Hs.194813   ESTs   2.71   PRSC_con, NCI-H345, PRSC_log       303745   AI142379       EST   2.71   PRSC_log, PRSC_con, RPWE-2       305197   AA666301       EST singleton (not in UniGene) with exon   2.71   EB, NCI-H520, OVCA-R       338725           CH22_EM:AC005500.GENSCAN.499-1   2.7   OALU6, MB-MDA-453, PC3       307799   AI351112       EST singleton (not in UniGene) with exon   2.7   HT29, BT474, MCF7       309598   AW173642   Hs.250106   EST   2.69   NCI-358, NCI-H69, NCI-H23       302727   L10141       EST   2.69   OVCA-R, BT474, PC3       308544   AI695133       EST singleton (not in UniGene) with exon   2.69   HT29, CALU6, MB-MDA-435s       322877   AA079727       EST duster (not in UniGene)   2.69   NCI-H345, NCI-H69, PRSC_con       325695           CH.14_hs gi|6552446   2.69   NCI-H69, NCI-H460, NCI-H460       307728   AI335557       EST singleton (not in UniGene) with exon   2.68   NCI-H69, PRSC_log, NCI-358       302399   N79624       EST   2.68   NCI-H69, PRSC_con, NCI-H345       309343   AW028652       EST singleton (not in UniGene) with exon   2.68   HT29, MB-MDA-231, MB-MDA-231       339360           CH22_BA354I12.GENSCAN.32-2   2.68   NCI-H69, PRSC_log, PRSC_con       337821           CH22_EMAC005500.GENSCAN.13-11   2.68   PRSC_con, PRSC_log, PRSC_log       337338           CH22_FGENES.717-7   2.66   NCI-H69, PRSC_con, PRSC_log       334510           CH22_FGENES.398_8   2.68   NCI-H460, NCI-H23, NCI-358       300918   AA491286   Hs.128792   ESTs   2.68   MB-MDA-435s, CALU6, DU145       335536           CH22_FGENES.574_2   2.67   NCI-H69, NCI-H345, PRSC_log       335311           CH22_FGENES.532_4   2.67   MB-MDA-435s, Caco2, A549       338959           CH22_DJ32I10.GENSCAN.23-31   2.67   NCI-H345, PRSC_con, NCI-H69       339081           CH22_DA59H18.GENSCAN.37-10   2.67   NCI-H345, RPWE-2, NCI-H69       334068           CH22_FGENES.327_23   2.67   PRSC_con, RPWE-2, PRSC_log       338976           CH22_DAS9HI8.GENSCAN.1-3   2.66   PRSC_con, PRSC_log, RPWE-2       325524           CH.12_hs gi|5866981   2.66   NCI-H345, RPWE-2, PRSC_con       333069           CH22_FGENES.76_5   2.66   NCI-H69, NCI-H345, PRSC_con       336203           CH22_FGENES.719_7   2.66   OVCA-R, PC3, A549       333133           CH22_FGENES.83_9   2.66   HT29, OVCA-R, A549       304074   T77842   Hs.142528   ESTs   2.65   DU145, CALU6, EB       330919   AA224594   Hs.86941   ESTs   2.65   PRSC_con, RPWE-2, LnCap       333248           CH22_FGENES.115_5   2.65   NCI-H345, PRSC_con, MB-MDA-231       336665           CH22_FGENES.42-2   2.65   NCI-H69, PRSC_log, PRSC_con       315322   AA770599       EST cluster (not in UniGene)   2.65   A549, MB-MDA-453, MB-MDA-435s       307474   AI264023       EST singleton (not in UniGene) with exon   2.65   NCI-H69, NCI-H345, RPWE-2       320221   AL050020   Hs.127384   DKFZPS64C196 protein   2.65   MB-MDA-453, MCF7, HT29       301767   AW361892       EST   2.65   NCI-H345, PRSC_con, PRSC_log       327246           CH.01_hs gi|5867547   2.65   EB, OVCA-R, DU145       337403           CH22_FGENES.752-2   2.65   PRSC_con, PRSC_log, RPWE-2       328221           CH.06_hs gi|5868099   2.64   MCF7, MB-MDA-231, BT474       336759           CH22_FGENES.133-2   2.64   NCI-H69, PRSC_log, PRSC_con       327532           CH.02_hs gi|6469818   2.64   PC3, CALU6, A549       305621   AA789095       EST singleton (not in UniGene) with exon   2.64   HT29, MB-MDA-231, MB-MDA-453       322931   AA099329   Hs.151784   ESTs   2.64   PRSC_con, RPWE-2, NCI-H345       327278           CH.01_hs gi|5867473   2.64   EB, NCI-H460, NCI-H69       332235   N51413   Hs.109284   ESTs   2.64   DU145, EB, OVCA-R       332792           CH22_FGENES.3_2   2.63   HT29, Caco2, A549       312340   A1862668   Hs.176333   ESTs   2.63   NCI-358, NCI-358, HT29       337484           CH22_FGENES.795-8   2.63   NCI-H69, NCI-H345, PRSC_con       325783           CH.14_hs gi|6456780   2.63   EB, OVCA-R, PC3       303672   AW502380   Hs.210527   ESTs   2.63   PRSC_log, NCI-H345, NCI-H69       306009   AA894560       EST singleton (not in UniGene) with exon   2.63   HT29, MB-MDA-231, CALU6       308548   AI695484       EST singleton (not in UniGene) with exon   2.63   PC3, A549, NCI-358       337930           CH22_EM:AC005500.GENSCAN.81-3   2.62   PC3, OVCA-R, MCF7       327791           CH.05_hs gi|5867977   2.62   PRSC_log, PRSC_con, NCI-H345       330925   AA232678   Hs.87073   ESTs   2.62   OVCA-R, MCF7, LnCap       327259           CH.01_hs gi|5867454   2.62   NCI-H345, PRSC_con, RPWE-2       302150   AF061756   Hs.152531   heart and neural crest derivatives expre   2.61   OVCA-R, PC3, A549       304881   AA598501   Hs.195188   glyceraldehyde-3-phosphate dehydrogenase   2.61   MB-MDA-435s, NCI-H23, MCF7       335956           CH22_FGENES.647_3   2.61   DU145, PRSC_con, PC3       326506           CH.19_hs gi|5867435   2.61   RPWE-2, NCI-H460, NCI-358       335863           CH22_FGENES.629_8   2.61   PC3, HT29, NCI-358       334752           CH22_FGENES.428_1   2.61   PRSC_con, NCI-H69, PRSC_log       333288           CH22_FGENES.128_19   2.61   HT29, NCI-358, Caco2       306709   AI024215   Hs.131477   EST   2.61   MB-MDA-435s, MCF7, BT474       305816   AA854776       EST singleton (not in UniGene) with exon   2.6   MB-MDA-453, MCF7, MB-MDA-435s       327264           CH.01_hs gi|5867461   2.6   MB-MDA-435s, MB-MDA-435s, MB-MDA-453       310905   AW075527   Hs.252259   ribosomal protein S3   2.6   OVCA-R, EB, DU145       324492   AA479507   Hs.135179   ESTs   2.6   DU145, EB, OVCA-R       322649   AA526549       EST cluster (not in UniGene)   2.6   PRSC_con, RPWE-2, PRSC_log       329384           CH.X_hs gi|5868869   2.6   NCI-H69, NCI-H345, PRSC_con       321240   M62378       EST duster (not in UniGene)   2.6   BT474, CALU6, MB-MDA-231       302751   AA299576   Hs.156110   Immunoglobulin kappa variable 1D-8   2.59   MCF7, MB-MDA-453, OVCA-R       305841   AA860348       EST singleton (not in UniGene) with exon   2.59   NCI-H345, PRSC_log, PRSC_con       324180   AA402242   Hs.122799   ESTs   2.58   EB, PC3, HT29       334196           CH22_FGENES.353_4   2.58   NCI-H345, NCI-H69, PRSC_con       338451           CH22_EM:AC005500.GENSCAN.359-39   2.58   MB-MDA-435s, NCI-H23, MCF7       300333   AW297396   Hs.227052   ESTs   2.58   PRSC_con, PRSC_log, NCI-H69       305046   AA632201       EST singleton (not in UniGene) with exon   2.58   NCI-H460, MB-MDA-453, MB-MDA-435s       305648   AA807652   Hs.156110   Immunoglobulin kappa variable 1D-8   2.57   PRSC_con, RPWE-2, NCI-H345       301744   W22230       EST   2.57   PRSC_con, PRSC_log, NCI-H345       329182           CH.X_hs gi|6056331   2.57   PRSC_con, RPWE-2, NCI-H345       318178   AW137425   Hs.158401   ESTs   2.57   MB-MDA-231, PRSC_con, BT474       330057           CH.17_p2 gi|6478962   2.57   NCI-H345, RPWE-2, PRSC_con       326552           CH.19._hs gi|5867308   2.57   NCI-H345, PRSC_con, RPWE-2       311956   T67085   Hs.188484   ESTs   2.57   HT29, MB-MDA-453, NCI-H460       327185           CH.01_hs gi|6117805   2.57   CALU6, HT29, EB       302183   NM_00224       EST   2.57   MCF7, PC3, OVCA-R       327263           CH.01_hs gi|6525274   2.56   PRSC_con, NCI-H69, PRSC_log       339164           CH22.DA59H18.GENSCAN.69-4   2.56   NCI-H69, PRSC_con, NCI-H345       332763   AA063554   Hs.90959   ESTs   2.58   RPWE-2, NCI-H345, PRSC_con       330579   U67733   Hs.154437   phosphodiesterase 2A; cGMP-stimulated   2.55   HT29, CALU6, PC3       329948           CH.16_p2 gi|5540101   2.55   NCI-H460, MCF7, MB-MDA-453       300282   AW044305   Hs.236131   ESTs; Highly similar to homeodomain-inte   2.55   NCI-H460, NCI-H23, NCI-H23       335448           CH22_FGENES.562_5   2.55   MB-MDA-453, BT474, MCF7       330959   H09174   Hs.26484   HIRA-interacting protein 3   2.55   MB-MDA-453, HT29, MCF7       307262   AI202100       EST singleton (not in UniGene) with exon   2.55   MCF7, DU145, MB-MDA-435s       335806           CH22_FGENES.616_8   2.55   NCI-H345, NCI-H69, PRSC_con       335782           CH22_FGENES.609_4   2.55   Caco2, MB-MDA-453, MB-MDA-435s       301703   AW301478       EST   2.55   PC3, MCF7, MB-MDA-453       329018           CH.X_hs gi|6249620   2.54   NCI-H69, PRSC_log, PRSC_con       329870           CH.14_p2 gi|6706435   2.54   NCI-H23, NCI-H460, NCI-358       334504           CH22_FGENES.398_2   2.54   HT29, BT474, MB.MDA-231       304707   AA564846       EST singleton (not in UniGene) with exon   2.53   NCI-H520, EB, NCI-H460       329326           CH.X_hs gi|5868806   2.53   MB-MDA-231, NCI-H345, NCI-H69       334418           CH22_FGENES.384_5   2.53   NCI-H23, NCI-358, NCI-H460       338124           CH22_EM:AC005500.GENSCAN.196-2   2.53   NCI-H69, PRSC_con, PRSC_log       318423   AI362671   Hs.214491   ESTs   2.53   OVCA-R, EB, DU145       333006           CH22_FGENES.60_3   2.53   NCI-H69, PRSC_con, PRSC_log       333668           CH22_FGENES.245_2   2.53   NCI-H69, PRSC_log, PRSC_con       333567           CH22_FGENES.184_2   2.63   NCI-H69, NCI-H345, PRSC_con       309592   AW172384       EST singleton (not in UniGene) with exon   2.52   LnCap, NCI-H69, DU145       328989           CH.09_hs gi|5868535   2.52   MB-MDA-435s, OVCA-R, EB       326725           CH.20_hs gi|6552456   2.52   PRSC_con, NCI-H345, NCI-H69       302996   AF054863       EST   2.52   HT29, BT474, CALU6       335733           CH22_FGENES.601_3   2.52   NCI-H69, PRSC_log, NCI-H345       336000           CH22_FGENES.658_1   2.52   LnCap, OVCA-R, DU145       327774           CH.05_hs gi|5867964   2.52   DU145, CALU6, HT29       328557           CH.07_hs gi|5868489   2.52   MB-MDA-453, MB-MDA-435s, MCF7       328228           CH.06_hs gi|5868105   2.52   NCI-H69, NCI-H345, PRSC_con       328305           CH.07_hs gi|6004478   2.52   NCI-H69, NCI-H460, PRSC_log       334010           CH22_FGENES.313_1   2.51   NCI-H69, PRSC_log, PRSC_con       339033           CH22_DA59H18.GENSCAN.26-1   2.51   NCI-H69, NCI-H345, PRSC_con       335340           CH22_FGENES.535_17   2.51   NCI-H69, PRSC_con, PRSC_log       300156   AI245582   Hs.233395   ESTs   2.51   PRSC_con, PRSC_log, NCI-H345       305880   AA866065   Hs.156110   Immunoglobulin kappa variable 1D-8   2.5   EB, OVCA-R, DU145       310841   AI968009   Hs.232024   ESTs   2.5   LnCap, NCI-358, CALU6       336908           CH22_FGENES.343-2   2.5   NCI-H345, RPWE-2, PRSC_log       304674   AA541735       EST singleton (not in UniGene) with exon   2.5   RPWE-2, NCI-H69, MCF7       314521   AW503939   Hs.107149   ESTs; Weakly similar to PTB-ASSOCIATED S   2.5   NCI-H460, EB, Caco2       307592   AI285739       EST singleton (not in UniGene) with exon   2.5   PRSC_con, NCI-H345, PRSC_log       331476   N26190   Hs.43768   ESTs   2.5   NCI-H345, NCI-H69, PRSC_con       325803           CH.14_hs gi|6552451   2.5   NCI-H345, RPWE-2, PRSC_con       306549   AA993796       EST singleton (not in UniGene) with exon   2.49   A549, OVCA-R, CALU6       304833   AA586504       EST singleton (not in UniGene) with exon   2.49   MCF7, DU145, LnCap       336333           CH22_FGENES.813.1   2.49   NCI-H345, PRSC_con, PRSC_log       332320   T71134   Hs.100551   EST   2.49   NCI-H345, LnCap, RPWE-2       328236           CH.06_hs gi|5868117   2.49   PRSC_con, NCI-H345, PRSC_log       317335   AI656979   Hs.130210   ESTs   2.49   MCF7, MB-MDA-453, PC3       339188           CH22_DA59H18.GENSCAN.72-16   2.48   NCI-H69, PRSC_con, PRSC_log       334235           CH22_FGENES.361_19   2.48   NCI-H520, MB-MDA-453, A549       301214   AW450950   Hs.157034   ESTs; Weakly similar to Unknown [ H.sapie     2.48   HT29, A549, A549       332843           CH22_FGENES.19_1   2.48   DU145, CALU6, EB       337431           CH22_FGENES.763-7   2.48   PRSC_con, RPWE-2, NCI-H69       336757           CH22_FGENES.131-1   2.48   NCI-H69, PRSC_log, PRSC_con       305403   AA723748       EST singleton (not in UniGene) with exon   2.48   NCI-H23, DU145, OVCA-R       330065           CH.19_p2 gi|6165044   2.48   PRSC_con, PRSC_log, NCI-H69       309245   AI972447       EST singleton (not in UniGene) with exon   2.48   MB-MDA-231, NCI-H69, HT29       328876           CH.07_hs gi|6525286   2.47   MB-MDA-231, CALU6, PC3       333944           CH22_FGENES.302_2   2.47   NCI-H69, RPWE-2, PRSC_log       328504           CH.07_hs gi|5868471   2.47   LnCap, MB-MDA-453, MB-MDA-435s       336120           CH22_EM:AC005500.GENSCAN.195-1   2.47   MB-MDA-231, NCI-H69, PRSC_con       306710   AI024221       EST singleton (not in UniGene) with exon   2.47   OVCA-R, EB, LnCap       305064   AA636012       EST singleton (not in UniGene) with exon   2.47   NCI-H69, RPWE-2, PRSC_con       329995           CH.16_p2 gi|4567166   2.47   OVCA-R, DU145, MB-MDA-453       315694   AI821743   Hs.168418   ESTs; Moderately similar to !!!! ALU SUB   2.46   EB, A549, LnCap       331004   H64622   Hs.32748   ESTs   2.46   EB, MCF7, MB-MDA-435s       305259   AA679225       EST singleton (not in UniGene) with exon   2.46   PRSC_con, NCI-H345, RPWE-2       304576   AA496563       EST singleton (not in UniGene) with exon   2.46   PRSC_con, RPWE-2, PRSC_log       318887   R60487   Hs.21065   ESTs   2.46   NCI-H345, Caco2, Caco2       308954   AI868958       EST singleton (not in UniGene) with exon   2.46   PRSC_con, PRSC_log, RPWE-2       301140   AI807692   Hs.207128   ESTs   2.46   OVCA-R, MB-MDA-231, HT29       322085   AA088500   Hs.170298   ESTs   2.46   PRSC_log, PRSC_con, NCI-H345       339130           CH22_DA59H18.GENSCAN.56-3   2.46   NCI-H345, PRSC_con, RPWE-2       337612           CH22_C20H12.GENSCAN.22-5   2.46   EB, A549, Caco2       313765   AW206181   Hs.185981   ESTs; Weakly similar to gag [ H.sapiens ]   2.45   RPWE-2, PRSC_log, PRSC_con       311665   AW294254   Hs.223742   ESTs   2.45   PRSC_log, RPWE-2, PRSC_con       328620           CH.07.hs gi|5868241   2.45   MB-MDA-453, MCF7, MB-MDA-435s       305361   AA708902       EST singleton (not in UniGene) with exon   2.45   HT29, MB-MDA-435s, A549       336243           CH22_FGENES.746_1   2.44   OVCA-R, MB-MDA-453, MB-MDA-435s       320299   H08323   Hs.177181   ESTs   2.44   PRSC_con, RPWE-2, NCI-H345       302535   H48676       EST   2.44   MB-MDA-453, EB, DU145       333465           CH22_FGENES.160_2   2.44   NCI-H69, PRSC_con, PRSC_log       334109           CH22_FGENES.330_8   2.44   NCI-H69, NCI-H345, PRSC_log       301749   F12998   Hs.90790   ESTs   2.44   NCI-H345, RPWE-2, PRSC_log       324575   AW502257       EST cluster (not in UniGene)   2.44   NCI-H345, PRSC_con, RPWE-2       337114           CH22_FGENES.494-17   2.44   NCI-H69, PRSC_log, PRSC_con       336087           CH22_FGENES.688_16   2.44   PRSC_con, Caco2, PRSC_log       315678   AI657119   Hs.120036   ESTs   2.44   NCI-358, PC3, NCI-H23       333258           CH22.FGENES.118_6   2.44   MB-MDA-231, HT29, CALU6       303798   V00505   Hs.36977   hemoglobin; delta   2.44   MB-MDA-435s, MCF7, MB-MDA-453       309759   AW268822       EST singleton (not in UniGene) with exon   2.44   MB-MDA-453, EB, MCF7       318946   AI122843       EST cluster (not in UniGene)   2.44   PC3, OVCA-R, DU145       321986   AL133656       EST cluster (not in UniGene)   2.44   DU145, CALU6, CALU6       336151           CH22_EM:AC005500.GENSCAN.207-5   2.44   PRSC_con, PRSC_log, RPWE-2       327056           CH.21_hs gi|6531965   2.44   PRSC_con, NCI-H345, RPWE-2       309605   AW182800       EST singleton (not in UniGene) with exon   2.43   NCI-358, NCI-H23, NCI-H520       335783           CH22_FGENES.610_3   2.43   PRSC_con, PRSC_log, NCI-H345       325790           CH.14_hs gi|6381957   2.43   MB-MDA-435s, MB-MDA-453, MB-MDA-453       339342           CH22_BA354I12, GENSCAN.27-10   2.43   BT474, MB-MDA-231, MB-MDA-453       335777           CH22_FGENES.607_13   2.43   DU145, EB, BT474       309972   AW450350   Hs.257283   ESTs   2.43   MCF7, MB-MDA-453, OVCA-R       308718   AI798009       EST singleton (not in UniGene) with exon   2.43   NCI-H345, PRSC_con, PRSC_log       338087           CH22_EM:AC005500.GENSCAN.174-16   2.43   DU145, PC3, CALU6       306930   AI124518       EST singleton (not in UniGene) with exon   2.43   NCI-H69, MCF7, BT474       319032   AW409728   Hs.80449   ESTs; Weakly similar to cytoplasmic dyne   2.43   RPWE-2, A549, NCI-H69       304330   AA157834       EST singleton (not in UniGene) with exon   2.43   MB-MDA-453, PC3, OVCA-R       320636   R54766   Hs.101120   ESTs   2.43   MCF7, MB-MDA-435s, MB-MDA-453       335281           CH22_FGENES.524_4   2.43   PC3, LnCap, A549       317431   AI675790   Hs.132453   ESTs   2.43   NCI-H345, RPWE-2, PRSC_log       306511   AA988891       EST singleton (not in UniGene) with exon   2.43   OVCA-R, EB, DU145       333298           CH22_FGENES.133_4   2.43   EB, DU145, PC3       328436           CH.07_hs gi|5868417   2.43   EB, LnCap, A549       333420           CH22_FGENES.146_11   2.43   NCI-H345, NCI-H69, PRSC_log       338113           CH22_EM:AC005500.GENSCAN.188-13   2.42   DU145, EB, CALU6       335188           CH22_FGENES.507_3   2.42   EB, A549, BT474       329164           CH.X_hs gi|5868691   2.42   RPWE-2, PRSC_con, PRSC_log       336316           CH22_FGENES.799_11   2.42   MB-MDA-435s, MCF7, NCI-H69       310831   AI927594   Hs.161142   ESTs   2.42   NCI-H345, PRSC_con, PRSC_log       327334           CH.01_hs gi|5902477   2.42   MB-MDA-453, MB-MDA-435s, MCF7       334017           CH22_FGENES.315_2   2.42   PRSC_con, PRSC_log, RPWE-2       308138   AI494446       EST singleton (not in UniGene) with exon   2.42   DU145, LnCap, EB       333074           CH22_FGENES.76_10   2.42   NCI-H69, RPWE-2, PRSC_log       306548   AA993109       EST singleton (not in UniGene) with exon   2.42   HT29, CALU6, LnCap       336516           CH22_FGENES.836_1   2.42   NCI-H69, PRSC_con, PRSC_log       306791   AI042387       EST singleton (not in UniGene) with exon   2.42   CALU6, DU145, EB       329411           CH.X_hs gi|6682549   2.42   OVCA-R, EB, LnCap       308659   AI750091       EST singleton (not in UniGene) with exon   2.41   EB, DU145, CALU6       313504   AI190405   Hs.143127   ESTs   2.41   DU145, EB, CALU6       326073           CH.17_hs gi|6682495   2.41   DU145, A549, MB-MDA-435s       334047           CH22_FGENES.326_5   2.41   PRSC_con, PRSC_log, NCI-H345       325464           CH.12_hs gi|5866947   2.41   NCI-358, NCI-H23, NCI-H460       334764           CH22_FGENES.428_13   2.41   NCI-H69, NCI-H345, RPWE-2       312737   AI033500   Hs.132895   ESTs   2.41   OVCA-R, DU145, CALU6       306591   AI000248       EST singleton (not in UniGene) with exon   2.41   MB-MDA-231, MCF7, DU145       333582           CH22_FGENES.201_2   2.41   NCI-H69, PRSC_con, PRSC_log       337843           CH22_EM:AC005500.GENSCAN.30-8   2.4   EB, LnCap, A549       335284           CH22_FGENES.526_6   2.4   NCI-H69, NCI-H345, PRSC_log       305134   AA653159       EST singleton (not in UniGene) with exon   2.4   DU145, HT29, MB-MDA-453       335527           CH22_FGENES.572_7   2.4   DU145, OVCA-R, EB       336795           CH22_FGENES.176-5   2.4   NCI-H69, NCI-H345, PRSC_log       303144   AF202889       EST   2.4   PRSC_con, PRSC_log, NCI-H69       334948           CH22_FGENES.465_15   2.4   PRSC_con, PRSC_log, RPWE-2       328860           CH.07_hs gi|6381928   2.4   PRSC_con, PRSC_log, NCI-H345       322929   AI365585   Hs.148246   ESTs   2.4   NCI-H460, A549, HT29       333561           CH22_FGENES.180_18   2.4   OVCA-R, EB, DU145       338239           CH22_EM:AC005500.GENSCAN.264-5   2.4   NCI-H69, NCI-H345, PRSC_con       323670   AL040411   Hs.161763   ESTs; Weakly similar to KIAA0738 protein   2.4   DU145, MB-MDA-453, EB       305903   AA873085       EST singleton (not in UniGene) with exon   2.4   MCF7, A549, NCI-H520       312573   AW297673   Hs.190526   ESTs   2.4   LnCap, NCI-H460, NCI-H23       334470           CH22_FGENES.394_1   2.4   NCI-H520, HT29, NCI-H23       333272           CH22_FGENES.122_1   2.39   NCI-H345, PRSC_con, RPWE-2       304010   AW518383   Hs.177592   ribosomal protein; large; P1   2.39   DU145, CALU6, EB       337316           CH22_FGENES.692-1   2.39   MCF7, BT474, OVCA-R       316769   AI914939   Hs.212184   ESTs   2.39   PRSC_con, NCI-H345, RPWE-2       336280           CH22_FGENES.763_4   2.39   NCI-H345, PRSC_log, PRSC_con       331223   T98872   Hs.194181   ESTs   2.39   DU145, HT29, PC3       337172           CH22_FGENES.565-2   2.39   EB, OVCA-R, DU145       300625   AI671992   Hs.143631   ESTs; Weakly similar to WASP-family prot   2.39   EB, NCI-H520, LnCap       337092           CH22_FGENES.465-12   2.39   PRSC_con, PRSC_log, NCI-H69       334528           CH22_FGENES.402_8   2.39   NCI-H345, PRSC_con, NCI-H69       338411           CH22_EM:AC005500.GENSCAN.341-7   2.39   NCI-H345, NCI-H69, PRSC_con       331344   AA357927   Hs.70208   ESTs   2.39   PC3, EB, A549       334044           CH22.FGENES.323_2   2.38   MB-MDA-231, MCF7, LnCap       333918           CH22_FGENES.296_7   2.38   RPWE-2, NCI-H345, EB       317168   AI042614   Hs.125910   ESTs   2.38   NCI-H345, PRSC_con, RPWE-2       333424           CH22_FGENES.147_4   2.38   DU145, MCF7, OVCA-R       317779   AW450515   Hs.128361   ESTs   2.38   EB, DU145, OVCA-R       315142   AI380577   Hs.190219   ESTs   2.38   OVCA-R, EB, CALU6       310471   AW270515   Hs.149596   ESTs   2.38   NCI-H460, NCI-H23, NCI-H23       325049   AW410339   Hs.256310   ESTs; Weakly similar to centaurin beta2   2.38   PRSC_con, RPWE-2, NCI-H345       305234   AA670431       EST singleton (not in UniGene) with exon   2.38   MB-MDA-453, MB-MDA-231, A549       337760           CH22_EM:AC000097.GENSCAN.116-8   2.38   PRSC_con, PRSC_log, RPWE-2       311502   AW204360   Hs.208662   ESTs   2.38   NCI-H345, NCI-H69, LnCap       337548           CH22_FGENES.844-5   2.38   MB-MDA-453, MCF7, CALU6       326981           CH.21_hs gi|6588016   2.38   NCI-H348, NCI-H69, PRSC_con       309600   AW182066       EST singleton (not in UniGene) with exon   2.37   RPWE-2, NCI-358, NCI-H69       328936           CH.08_hs gi|5868500   2.37   OVCA-R, MB-MDA-453, CALU6       327937           CH.06_hs gi|5868192   2.37   BT474, EB, OVCA-R       328282           CH.07_hs gi|5868353   2.37   DU145, CALU6, CALU6       303607   AL046388   Hs.208206   ESTs; Weakly similar to Naf1 alpha prote   2.37   LnCap, PRSC_log, NCI-H345       304227   N94974   Hs.75344   ribosomal protein S4; X-linked   2.37   EB, PC3, OVCA-R       314101   AW452279   Hs.257542   ESTs   2.37   OVCA-R, CALU6, CALU6       325026   AI671168   Hs.12285   ESTs   2.37   NCI-H345, PRSC_con, PRSC_log       315015   AI659989   Hs.132625   ESTs   2.37   MB-MDA-453, MB-MDA-231, LnCap       328662           CH.07_hs gi|6004473   2.37   NCI-H345, RPWE-2, PRSC_con       305867   AA864572       EST singleton (not in UniGene) with exon   2.37   MCF7, MB-MDA-453, MB-MDA-231       333296           CH22_FGENES.132_3   2.37   EB, PC3, CALU6       331070   R01116   Hs.182059   ESTs   2.36   OVCA-R, MB-MDA-453, A549       333698           CH22_FGENES.250_12   2.36   HT29, OVCA-R, Caco2       316423   AA758756   Hs.121380   ESTs   2.36   HT29, MCF7, MB-MDA-435s       323189   AL121194   Hs.120589   ESTs   2.36   PC3, NCI-H460, DU145       318889   Z43296   Hs.18720   programmed cell death 8 (apoptosis-induc   2.36   OVCA-R, A549, MB-MDA-453       334237           CH22_FGENES.362_1   2.36   NCI-H345, NCI-H69, LnCap       315931   AI700148   Hs.117328   ESTs   2.36   MCF7, NCI-H345, DU145       326884           CH.20_hs gi|668251 1   2.36   A549, EB, PC3       333132           CH22_FGENES.83_8   2.36   NCI-H69, HT29, EB       306574   AA995719   Hs.76067   heat shock 27 kD protein 1   2.36   RPWE-2, PRSC_log, PRSC_con       324416   AI669524   Hs.194115   ESTs   2.36   NCI-H345, RPWE-2, PRSC_con       329496           CH.10_p2 gi|3983518   2.35   HT29, MCF7, MB-MDA-231       320994   H22381       EST cluster (not in UniGene)   2.35   NCI-H23, A549, CALU6       320481   AA461139   Hs.24372   ESTs; Weakly similar to dJ207H1.1 [ H.sap     2.35   PRSC_con, RPWE-2, PRSC_log       309958   AW444488       EST singleton (not in UniGene) with exon   2.35   NCI-H345, PRSC_con, PRSC_log       327009           CH.21_hs gi|5867664   2.35   HT29, BT474, MCF7       309594   AW172821   Hs.181165   eukaryotic translation elongation factor   2.35   HT29, DU145, EB       335468           CH22_FGENES.567_4   2.35   NCI-H69, PRSC_con, NCI-H345       304269   AA069029       EST singleton (not in UniGene) with exon   2.35   PRSC_con, PRSC_log, RPWE-2       305877   AA865649       EST singleton (not in UniGene) with exon   2.35   A549, MCF7, OVCA-R       305700   AA815428       EST singleton (not in UniGene) with exon   2.35   PRSC_con, NCI-H345, PRSC_log       326423           CH.19_hs gi|5867369   2.34   PC3, MCF7, LnCap       334560           CH22_FGENES.404_3   2.34   HT29, NCI-H460, MB-MDA-435s       337100           CH22_FGENES.472-3   2.34   PRSC_log, PRSC_con, RPWE-2       301505   AW014374   Hs.144849   ESTs   2.34   CALU6, MB-MDA-231, DU145       312142   AW298359   Hs.221069   ESTs   2.34   PRSC_con, RPWE-2, PRSC_log       305787   AA845035       EST singleton (not in UniGene) with exon   2.34   NCI-H23, NCI-H520, NCI-H460       338686           CH22_EM:AC005500.GENSCAN.472-5   2.33   BT474, MB-MDA-231, MB-MDA-453       331977   AA465207   Hs.125887   ESTs   2.33   OVCA-R, A549, MB-MDA-435s       314687   M79114   Hs.135177   ESTs   2.33   NCI-H69, PRSC_con, NCI-H345       336089           CH22_FGENES.688_18   2.33   PRSC_con, Caco2, PRSC_log       338952           CH22_DJ32110.GENSCAN.23-22   2.33   PC3, OVCA-R, HT29       334612           CH22_FGENES.411_11   2.33   OVCA-R, MB-MDA-453, EB       338223           CH22_EM:AC005500.GENSCAN.250-10   2.33   DU145, MB-MDA-453, MCF7       327845           CH.05_hs gi|6531962   2.32   OVCA-R, MB-MDA-453, PC3       308187   AI538108   Hs.156110   Immunoglobulin kappa variable 10-8   2.32   NCI-H69, NCI-358, PRSC_con       317767   AW294164   Hs.128340   ESTs; Weakly similar to Cdc42 GTPase-act   2.32   BT474, CALU6, MB-MDA-231       330408   L10343   Hs.112341   protease inhibitor 3; skin-derived (SKAL   2.32   PC3, Caco2, HT29       319003   R17712       EST cluster (not in UniGene)   2.32   MCF7, PC3, MB-MDA-453       323022   AI066733   Hs.133885   ESTs   2.32   CALU6, MB-MDA-231, DU145       303148   R73167   Hs.127317   ESTs; Weakly similar to CYTOCHROME P450   2.32   NCI-H345, PRSC_con, RPWE-2       303215   AW250314       EST   2.32   NCI-H345, PRSC_con, PRSC_log       318891   H10477   Hs.196208   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.32   NCI-H69, LnCap, NCI-H345       336653           CH22_FGENES.33-4   2.32   DU145, EB, LnCap       333329           CH22_FGENES.138_22   2.32   DU145, BT474, MB-MDA-231       301980   U69962   Hs.121498   potassium voltage-gated channel; Shab-re   2.31   NCI-H345, MB-MDA-231, LnCap       336968           CH22_FGENES.375-28   2.31   HT29, BT474, EB       308539   AI694191       EST singleton (not in UniGene) with exon   2.31   NCI-H345, NCI-H69, PRSC_log       326417           CH.19_hs gi|5867362   2.31   HT29, MCF7, BT474       328861           CH.07_hs gi|6381923   2.31   NCI-H520, NCI-H460, NCI-H23       329254           CH.X_hs gi|5868733   2.31   RPWE-2, NCI-H345, PRSC_con       303075   W88779   Hs.59125   ESTs   2.3   DU145, OVCA-R, EB       335131           CH22_FGENES.497_15   2.3   NCI-H69, NCI-H345, PRSC_log       303129   AA308334   Hs.172210   MUF1 protein   2.3   LnCap, DU145, HT29       327067           CH.21_hs gi|6531965   2.3   NCI-H345, NCI-H69, MB-MDA-435s       324064   AW137650       EST cluster (not in UniGene)   2.3   DU145, HT29, EB       325965           CH.16_hs gi|5887147   2.3   NCI-H69, NCI-H345, RPWE-2       334525           CH22_FGENES.402_4   2.3   NCI-H345, PRSC_con, NCI-H69       336654           CH22_FGENES.34-2   2.3   BT474, PC3, ME-MDA-453       302348   AF100779   Hs.194680   WNT1 inducible signaling pathway protein   2.3   LnCap, CALU6, DU145       309275   AI989570       EST singleton (not in UniGene) with exon   2.3   NCI-H460, NCI-H23, NCI-H520       329246           CH.X_hs gi|5868732   2.3   NCI-H69, NCI-H345, PRSC_log       305557   AA774834       EST singleton (not in UniGene) with exon   2.3   CALU6, CALU6, MCF7       322907   AA084941       EST cluster (not in UniGene)   2.3   MB-MDA-231, CALU6, EB       318683   AI703241   Hs.202653   ESTs; Weakly similar to Xin [ M.musculus ]   2.29   NCI-H345, PRSC_con, RPWE-2       309233   AI971416       EST singleton (not in UniGene) with exon   2.29   CALU6, OVCA-R, EB       308913   AI860692   Hs.119122   ribosomal protein L13a   2.29   MB-MDA-435s, MCF7, HT29       335827           CH22_FGENES.620_1   2.29   PRSC_con, PRSC_log, RPWE-2       334066           CH22_FGENES.327_21   2.29   PRSC_con, PRSC_log, NCI-H345       302656   AW293005   Hs.220905   ESTs   2.29   NCI-H23, Caco2, CALU6       308974   AI872290   Hs.140   immunoglobulin gamma 3 (Gm marker)   2.29   CALU6, A549, NCI-H69       333607           CH22_FGENES.216_2   2.29   OVCA-R, MCF7, A549       335174           CH22_FGENES.504_4   2.29   HT29, A549, MB-MDA-453       332028   AA489680   Hs.134406   ESTs; Weakly similar to Dim1p homolog [H   2.29   EB, A549, DU145       336417           CH22_FGENES.823_39   2.29   NCI-H69, NCI-H345, PRSC_log       323426   AA251401       EST cluster (not in UniGene)   2.29   HT29, MB-MDA-231, BT474       336618           CH22_FGENES.2-1   2.29   NCI-358, NCI-H460, NCI-H69       310017   AI188739   Hs.148488   ESTs   2.29   NCI-H345, PRSC_log, PRSC_con       334055           CH22_FGENES.327_6   2.28   DU145, OVCA-R, MB-MDA-453       337168           CH22_FGENES.562-28   2.28   NCI-H69, PRSC_log, NCI-H345       329824           CH.14_p2 gi|6630758   2.28   NCI-H23, CALU6, RPWE-2       333891           CH22_FGENES.292_13   2.28   NCI-H69, MB-MDA-231, RPWE-2       339127           CH22_DAS9H18.GENSCAN.55-1   2.28   PRSC_con, NCI-H345, RPWE-2       305686   AA812726       EST singleton (not in UniGene) with exon   2.28   NCI-H520, NCI-H23, NCI-H460       329782           CH.14_p2 gi|5912597   2.28   NCI-H69, NCI-H345, PRSC_log       311059   AI810001   Hs.175346   ESTs   2.28   MCF7, BT474, MB-MDA-435s       336934           CH22_FGENES.351-1   2.28   BT474, HT29, MB-MDA-435s       314893   AA761093       EST cluster (not in UniGene)   2.28   OVCA-R, HT29, DU145       331596   N72574   Hs.50220   ESTs   2.28   A549, MCF7, NCI-358       330729   AA258559   Hs.3736   ESTs; Weakly similar to DELTA-LIKE PROTE   2.28   MB-MDA-231, CALU6, MCF7       338285           CH22_EM:AC005500.GENSCAN.293-3   2.27   NCI-H69, PRSC_log, PRSC_con       300154   AI245127   Hs.179331   ESTs   2.27   NCI-H23, NCI-H520, NCI-358       306383   AA969078   Hs.183698   ribosomal protein L29   2.27   RPWE-2, NCI-H345, PRSC_log       309005   AI884454       EST singleton (not in UniGene) with exon   2.27   A549, MCF7, BT474       332995           CH22_FGENES.58_2   2.27   RPWE-2, NCI-H345, PRSC_log       337426           CH22_FGENES.761-3   2.27   DU145, EB, CALU6       337778           CH22_EM:AC000097.GENSCAN.119-20   2.27   NCI-H69, PRSC_con, PRSC_log       329705           CH.14_p2 gi|6065790   2.27   PRSC_con, PRSC_log, RPWE-2       335971           CH22_FGENES.652_4   2.27   PRSC_log, MB-MDA-231, NCI-H23       315862   AI075848   Hs.133996   ESTs   2.27   HT29, MB-MDA-435s, OVCA-R       316466   AI911204   Hs.126365   ESTs   2.27   NCI-8460, NCI-358, BT474       334430           CH22_FGENES.385_3   2.27   NCI-H345, NCI-H69, PRSC_con       331941   AA452257   Hs.99272   ESTs   2.26   PRSC_con, LnCap, PRSC_log       301230   AW269804   Hs.153019   ESTs   2.26   NCI-H345, PRSC_log, NCI-H520       317394   AI935024   Hs.190518   ESTs   2.26   NCI-H345, PRSC_con, PRSC_log       306220   AA928363       EST singleton (not in UniGene) with exon   2.26   NCI-H345, PRSC_con, PRSC_log       304134   H54627       EST singleton (not in UniGene) with exon   2.26   DU145, CALU6, PC3       335421           CH22_FGENES.55_1   2.26   NCI-H69, PRSC_con, PRSC_log       305260   AA679280   Hs.156110   Immunoglobulin kappa variable 10-8   2.26   NCI-H345, NCI-H69, PRSC_con       303592   AA421129       EST   2.26   CALU6, OVCA-R, DU145       317982   AI004985   Hs.130607   ESTs   2.26   PC3, MB-MDA-435s, A549       325304           CH11_hs gi|5866910   2.26   MCF7, CALU6, A549       334118           CH22_FGENES.330_19   2.26   PRSC_con, NCI-H69, PRSC_log       335687           CH22_FGENES.596_2   2.26   A549, CALU6, LnCap       334035           CH22_FGENES.322.3   2.26   NCI-H345, PRSC_con, RPWE-2       305454   AA738413       EST singleton (not in UniGene) with exon   2.25   EB, HT29, CALU6       335902           CH22_FGENES.635_10   2.25   EB, DU145, HT29       339215           CH22_FF113D11.GENSCAN.6-10   2.25   PRSC_con, PRSC_log, RPWE-2       328810           CH.07_hs gi|5868327   2.25   PC3, OVCA-R, MB-MDA-453       337396           CH22_FGENES.749-1   2.25   EB, A549, DU145       336808           CH22_FGENES.205-3   2.25   NCI-H345, NCI-H69, PRSC_con       305808   AA853958       EST singleton (not in UniGene) with exon   2.24   MB-MDA-453, DU145, EB       333571           CH22_FGENES.188_2   2.24   MCF7, MB-MDA-453, PC3       323023   AA225188   Hs.258539   ESTs   2.24   EB, DU145, CALU6       334626           CH22_FGENES.416_2   2.24   NCI-H69, NCI-H345, PRSC_log       333593           CH22_FGENES.210_2   2.24   NCI-H69, NCI-H345, PRSC_con       326708           CH.20_hs gi|5867593   2.24   NCI-H460, NCI-H23, NCI-H520       314502   AI041717   Hs.132141   ESTs   2.23   NCI-H345, RPWE-2, PRSC_con       309181   AI951727       EST singleton (not in UniGene) with exon   2.23   PRSC_con, PC3, MB-MDA-231       324926   H56196   Hs.117798   ESTs   2.23   EB, EB, DU145       333632           CH22_FGENES.227_3   2.23   CALU6, CALU6, MB-MDA-453       328243           CH.06_hs gi|6056292   2.23   PC3, LnCap, LnCap       327037           CH.21_hs gi|6531965   2.23   LnCap, DU145, EB       307380   AI222985       EST singleton (not in UniGene) with exon   2.23   NCI-H345, PRSC_con, PRSC_log       334766           CH22_FGENES.428_15   2.23   PRSC_log, NCI-H345, RPWE-2       335236           CH22_FGENES.515_8   2.23   OVCA-R, MCF7, BT474       336615           CH22_FGENES.613_5   2.23   NCI-H69, PRSC_log, PRSC_con       307558   AI281998       EST singleton (not in UniGene) with exon   2.23   DU145, OVCA-R, CALU6       308029   AI457115   Hs.62954   ferritin; heavy polypeptide 1   2.23   EB, OVCA-R, MB-MDA-453       331508   N47559   Hs.46732   EST   2.23   MB-MDA-453, MCF7, BT474       320980   AJ237672   Hs.214142   5;10-methylenetetrahydrafolate reductase   2.23   OVCA-R, EB, EB       304241   AA010976       EST singleton (not in UniGene) with exon   2.23   BT474, MB-MDA-435s, MB-MDA-231       314682   AI190864   Hs.178226   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.23   MB-MDA-231, MCF7, OVCA-R       308382   AI624301       EST singleton (not in UniGene) with exon   2.22   OVCA-R, BT474, CALU6       314476   AW207857   Hs.169604   ESTs   2.22   DU145, EB, A549       327864           CH.06_hs gi|5868130   2.22   NCI-H69, PRSC_log, PRSC_con       337279           CH22_FGENES.665-2   2.22   NCI-H345, NCI-H69, PRSC_con       302263   AA325517       EST   2.22   BT474, NCI-H520, DU145       322840   AA083710       EST cluster (not in UniGene)   2.22   HT29, MB-MDA-453, CALU6       307574   AI283549       EST singleton (not in UniGene) with exon   2.22   OVCA-R, CALU6, BT474       319027   AA716812       EST cluster (not in UniGene)   2.22   LnCap, NCI-H69, NCI-H69       305925   AA877883       EST singleton (not in UniGene) with exon   2.22   NCI-H345, NCI-H69, NCI-H69       329725           CH.14_p2 gi|6065785   2.22   NCI-H69, PRSC_con, NCI-H345       316194   AW298529   Hs.255774   ESTs   2.22   CALU6, EB, NCI-H520       301119   AF142579       EST   2.22   A549, OVCA-R, EB       333815           CH22_FGENES.282_4   2.22   MB-MDA-435s, EB, MB-MDA-453       334358           CH22_FGENES.378_1   2.22   NCI-H345, RPWE-2, PRSC_con       303763   AF043250   Hs.30928   DNA segment on chromosome 19 (unique) 11   2.21   Caco2, NCI-H23, NCI-H520       335593           CH22_FGENES.581_32   2.21   NCI-H345, PRSC_log, RPWE-2       334026           CH22_FGENES.318_3   2.21   NCI-H69, PRSC_con, NCI-H345       322224   AF086064       EST cluster (not in UniGene)   2.21   PRSC_con, PRSC_log, RPWE-2       309836   AW295497   Hs.157397   ESTs   2.21   NCI-H345, PRSC_con, RPWE-2       332669   M33374   Hs.661   NADH dehydrogenase (ubiquinone) 1 betas   2.21   NCI-H520, CALU6, OVCA-R       307629   AI300246       EST singleton (not in UniGene) with exon   2.21   MB-MDA-231, MB-MDA-453, HT29       300470   T87841       EST   2.21   PC3, EB, CALU6       330084           CH.19_p2 gi|6165044   2.21   NCI-H69, PRSC_con, BT474       338819           CH22_DJ246D7.GENSCAN.1-24   2.21   NCI-H69, RPWE-2, PRSC_log       337797           CH22_EM:AC005500.GENSCAN.3-4   2.21   LnCap, NCI-H69, NCI-H520       328025           CH.06_hs gi|5902482   2.2   RPWE-2, PRSC_con, PRSC_log       326240           CH.17_hs gi|5867260   2.2   EB, LnCap, MB-MDA-453       312865   AW005376   Hs.173280   ESTs   2.2   DU145, DU145, OVCA-R       338450           CH22_EM:AC005500.GENSCAN.359-36   2.2   MCF7, MB-MDA-453, MB-MDA-435s       302532   U60181   Hs.248115   growth hormone secretagogue receptor   2.2   PRSC_con, PRSC_log, PRSC_log       321132   AA081495       EST cluster (not in UniGene)   2.2   NCI-H23, NCI-H520, NCI-358       337787           CH22_EM:AC000097.GENSCAN.123-3   2.2   EB, PC3, LnCap       337032           CH22_FGENES.438-3   2.2   NCI-H69, NCI-H345, RPWE-2       300026   M11507       AFFX control: transferrin receptor   2.2   HT29, EB, MB-MDA-231       333139           CH22_FGENES.83_16   2.2   HT29, MB-MDA-453, Caco2       334298           CH22_FGENES.372_4   2.2   PRSC_con, PRSC_log, RPWE-2       335002           CH22_FGENES.470_7   2.2   PRSC_con, NCI-H345, NCI-H345       335000           CH22_FGENES.470_5   2.2   EB, PC3, A549       337298           CH22_FGENES.678-3   2.2   NCI-H69, A549, HT29       302481   AF104253   Hs.241381   cofactor required for Sp1 transcriptiona   2.2   EB, CALU6, LnCap       334819           CH22_FGENES.436_15   2.19   CALU6, BT474, Caco2       300426   AW452660   Hs.253296   ESTs   2.19   DU145, CALU6, HT29       302569   AC004472       multiple UniGene matches   2.19   RPWE-2, PRSC_log, PRSC_con       339401           CH22_BA232E17.GENSCAN.7-7   2.19   NCI-H345, NCI-H69, PRSC_log       328791           CH.07_hs gi|5868309   2.19   DU145, PC3, HT29       337333           CH22_FGENES.711-3   2.19   NCI-H69, NCI-H345, PRSC_log       339363           CH22_BA354I12.GENSCAN.33-6   2.19   NCI-H69, PRSC_log, PRSC_con       329429           CH.Y_hs gi|5868882   2.19   CALU6, HT29, OVCA-R       336927           CH22_FGENES.348-3   2.19   NCI-869, PRSC_log, NCI-358       336351           CH22_FGENES.816_3   2.19   DU145, EB, MB-MDA-231       313466   AA004731   Hs.148876   ESTs   2.19   CALU6, DU145, OVCA-R       307433   AI244895       EST singleton (not in UniGene) with exon   2.19   NCI-H23, NCI-H23, NCI-358       336590           CH22_FGENES.51_2   2.19   PRSC_con, NCI-H69, PRSC_log       310758   AI770001   Hs..209445   ESTs   2.18   EB, MB-MDA-231, BT474       327823           CH.05_hs gi|5867968   2.18   PRSC_con, NCI-H69, NCI-H345       313257   N92638       EST cluster (not in UniGene)   2.18   PRSC_log, RPWE-2, PRSC_con       335377           CH22_FGENES.543_17   2.18   PC3, MB-MDA-435s, CALU6       303958   AL042931       EST singleton (not in UniGene) with exon   2.18   NCI-H345, RPWE-2, PRSC_con       320153   AF064594   Hs.120360   phospholipase A2; group VI   2.18   LnCap, PC3, MB-MDA-435s       335201           CH22_FGENES.508_10   2.18   OVCA-R, DU145, HT29       338591           CH22.EMAC005500.GENSCAN.434-4   2.18   NCI-H69, NCI-H345, RPWE-2       331958   AA455960   Hs.99405   ESTs   2.18   MCF7, NCI-H23, NCI-H460       337218           CH22_FGENES.614-2   2.18   CALU6, A549, MCF7       309470   AW118833       EST singleton (not in UniGene) with exon   2.18   PC3, EB, MB-MDA-435s       331896   AA435495   Hs.97174     H sapiens  mRNA; cDNA DKFZp566E164 (from   2.18   RPWE-2, NCI-H69, PRSC_log       330275           CH.05_p2 gi|6671904   2.18   NCI-H345, PRSC_log, PRSC_con       335817           CH22_FGENES.618_5   2.18   A549, Caco2, PC3       332896           CH22_FGENES.35_10   2.18   NCI-H345, RPWE-2, PRSC_log       303294   AA205300       EST   2.17   MB-MDA-435s, A549, MCF7       338703           CH22_EM:AC005500.GENSCAN.480-2   2.17   HT29, BT474, NCI-H69       300115   AI215044   Hs.208130   ESTs   2.17   PC3, OVCA-R, HT29       330979   H22466   Hs.31795   ESTs   2.17   MCF7, EB, MB-MDA-435s       317246   AW105092   Hs.155690   ESTs   2.17   MB-MDA-453, DU145, EB       329078           CH.X_hs gi|5868597   2.17   MB-MDA-453, MB-MDA-231, BT474       312554   AI222630   Hs.109390   ESTs   2.17   NCI-H520, OVCA-R, MCF7       323207   AI052795   Hs.192201   ESTs   2.17   NCI-H69, NCI-H345, PRSC_log       301894   AA484435   Hs.41997   alpha-1-B glycoprotein   2.17   PRSC_con, LnCap, PRSC_log       329097           CH.X_hs gi|5868624   2.16   MB-MDA-231, MCF7, NCI-358       328328           CH.07_hs gi|5868375   2.16   NCI-H345, PRSC_con, NCI-H69       302671   AA522440   Hs.135917   ESTs   2.16   BT474, DU145, A549       329201           CH.X_hs gi|5868718   2.16   OVCA-R, PC3, MB-MDA-435s       329902           CH.15_p2 gi|6634760   2.16   PRSC_con, NCI-H69, NCI-H345       334435           CH22_FGENES.385_10   2.16   PRSC_con, NCI-H345, RPWE-2       330742   AA400979   Hs.25691   calcitonin receptor-like receptor activi   2.16   MCF7, MB-MDA-453, PC3       328484           CH.07_hs gi|5868454   2.16   NCI-H69, PRSC_log, NCI-H345       334784           CH22_FGENES.432_9   2.16   PRSC_log, RPWE-2, PRSC_con       337771           CH22.EM:AC000097.GENSCAN.119-10   2.16   NCI-H69, PRSC_con, RPWE-2       300181   AI284955   Hs.157568   ESTs; Weakly similar to ataxin-2 [ M.musc     2.16   DU145, EB, CALU6       300268   AI539446   Hs.245450   ESTs   2.16   PRSC_con, RPWE-2, PRSC_log       309575   AW168096   Hs.195188   glyceraldehyde-3-phosphate dehydrogenase   2.16   A549, NCI-H23, MB-MDA-453       336548           CH22_FGENES.841_5   2.16   NCI-H345, NCI-H69, MB-MDA-231       328506           CH.07_hs gi|5868471   2.16   EB, A549, CALU6       330189           CH.05_p2 gi|6165182   2.16   NCI-H460, MCF7, MB-MDA-453       305480   AA746500   Hs.25911   HLA-B associated transcript-2   2.16   EB, DU145, NCI-358       302270   R56151       EST   2.16   OVCA-R, MB-MDA-435s, PRSC_con       306669   AI004899       EST singleton (not in UniGene) with exon   2.16   PRSC_log, PRSC_con, NCI-H345       325887           CH.16_hs gi|5867087   2.16   EB, CALU6, NCI-358       327015           CH.21_hs gi|5867664   2.15   EB, PC3, HT29       338576           CH22_EM:AC005500.GENSCAN.429-1   2.15   NCI-H69, NCI-H345, PRSC_con       333592           CH22_FGENES.209_2   2.15   NCI-H69, OVCA-R, PRSC_con       317253   AW071241   Hs.199685   ESTs   2.15   MB-MDA-435s, NCI-H23, MB-MDA-453       302301   R67493   Hs.127150   ESTs; Weakly similar to ZINC FINGER PROT   2.15   PC3, MCF7, MB-MDA-435s       336858           CH22_FGENES.293-8   2.15   RPWE-2, PRSC_con, NCI-H69       308417   AI640693   Hs.2186   eukaryotic translation elongation factor   2.15   EB, OVCA-R, CALU6       338177           CH22_EM:AC005500.GENSCAN.219-5   2.15   NCI-H345, NCI-H23, NCI-H520       337592           CH22_C20H12.GENSCAN.6-7   2.15   PC3, A549, HT29       325945           CH.16_hs gi|5867138   2.15   MB-MDA-453, MB-MDA-435s, DU145       335262           CH22_FGENES.520_3   2.15   EB, PC3, A549       333665           CH22_FGENES.244_1   2.15   PRSC_con, RPWE-2, PRSC_log       333710           CH22_FGENES.250_25   2.14   PRSC_log, NCI-H69, PRSC_con       304927   AA604728   Hs.195188   glyceraldehyde-3-phosphate dehydrogenase   2.14   LnCap, PC3, MCF7       336999           CH22_FGENES.417-20   2.14   NCI-H69, NCI-H345, PRSC_con       313283   W32480   Hs.157099   ESTs   2.14   EB, MB-MDA-231, A549       306221   AA928686       EST singleton (not in UniGene) with exon   2.14   NCI-H460, PRSC_con, NCI-H23       333205           CH22_FGENES.102_5   2.14   NCI-H69, PRSC_con, PRSC_log       312932   AI804218   Hs.209614   ESTs   2.14   PRSC_con, NCI-H345, RPWE-2       328938           CH.08_hs gi|5868500   2.14   HT29, PC3, MB-MDA-453       326748           CH.20_hs gi|5867611   2.14   NCI-H345, NCI-H69, PRSC_con       337964           CH22_EM:AC005500.GENSCAN.100-9   2.14   RPWE-2, PRSC_con, PRSC_log       337984           CH22_EM:AC005500.GENSCAN.110-2   2.14   EB, DU145, NCI-H345       337704           CH22_EM.AC000097.GENSCAN.87-6   2.14   NCI-H69, NCI-H460, NCI-358       302162   AF119046       EST   2.14   MB-MDA-435s, PC3, EB       303192   AA081755   Hs.8059   ESTs; Highly similar to SYNAPTOTAGMIN IV   2.14   MB-MDA-435s, MB-MDA-435s, MB-MDA-453       306200   AA926816       EST singleton (not in UniGene) with exon   2.14   MB-MDA-453, CALU6, DU145       303996   AW515979   Hs.84298   CD74 antigen (invanant polypptd of majo   2.14   LnCap, MB-MDA-231, BT474       325409           CH.12_hs gi|5866921   2.14   PRSC_log, PRSC_con, RPWE-2       308558   AI700145   Hs.172182   poly(A)-binding protein; cytoplasmic 1   2.14   MCF7, ER, MB-MDA-435s       302185   AA243837   Hs.156915   ESTs   2.14   MB-MDA-453, MCF7, EB       303021   W39612       EST   2.14   PRSC_con, NCI-H69, RPWE-2       301005   AW451916   Hs.210848   ESTs   2.14   DU145, EB, HT29       336029           CH22_FGENES.672_4   2.14   NCI-H69, PRSC_con, RPWE-2       305443   AA736653       EST singleton (not in UniGene) with exon   2.14   NCI-358, NCI-H520, NCI-H23       335485           CH22_FGENES.570_17   2.13   NCI-H460, MB-MDA-435s, MCF7       304817   AA584712       EST singleton (not in UniGene) with exon   2.13   MCF7, MCF7, NCI-H520       309859   AW298760       EST singleton (not in UniGene) with exon   2.13   NCI-H69, PRSC_con, LnCap       326206           CH.17_hs gi|5867219   2.13   EB, MB-MDA-231, LnCap       303656   AA437189   Hs.122574   ESTs   2.13   LnCap, MB-MDA-435s, EB       334745           CH22_FGENES.426_3   2.13   OVCA-R, DU145, MB-MDA-453       318504   T26453       EST cluster (not in UniGene)   2.13   RPWE-2, LnCap, CALU6       306839   AI077385       EST singleton (not in UniGene) with exon   2.13   MCF7, MB-MDA-453, MB-MDA-435s       303843   W94322   Hs.58094   melanoma inhibitory activity   2.13   MB-MDA-435s, NCI-H345, RPWE-2       308444   AI659398   Hs.197097   EST   2.13   MB-MDA-453, MCF7, BT474       301322   AW448965   Hs.256305   ESTs   2.13   NCI-H345, LnCap, PC3       326997           CH.21_hs gi|5867660   2.13   HT29, A549, CALU6       326793           CH.20_hs gi|5867631   2.13   PRSC_log, PRSC_con, MB-MDA-453       320360   H12405       EST cluster (not in UniGene)   2.12   MB-MDA-231, BT474, HT29       316301   AW206279   Hs.192009   ESTs   2.12   DU145, DU145, EB       335371           CH22_FGENES.543_9   2.12   PC3, MB-MDA-435s, DU145       301178   AA828385       EST   2.12   EB, OVCA-R, LnCap       326136           CH.17_hs gi|5867202   2.12   RPWE-2, PRSC_log, PRSC_con       339213           CH22_FF113D11.GENSCAN.6.8   2.12   OVCA-R, PC3, MB-MDA-231       335980           CH22_FGENES.653_2   2.12   BT474, BT474, OVCA-R       314380   AA758797   Hs.192807   ESTs   2.11   PRSC_con, PRSC_log, RPWE-2       306779   AI041302       EST singleton (not in UniGene) with exon   2.11   NCI-H345, PRSC_con, PRSC_log       335774           CH22_FGENES.607_10   2.11   PC3, A549, MB-MDA-453       334914           CH22_FGENES.457_3   2.11   PRSC_con, NCI-H345, NCI-H69       304619   AA515554   Hs.119598   ribosomal protein L3   2.11   EB, MB-MDA-453, MB-MDA-435s       303358   AI199714   Hs.158149   ESTs   2.11   CALU6, OVCA-R, DU145       306558   AA994743       EST singleton (not in UniGene) with exon   2.11   HT29, MB-MDA-453, CALU6       337781           CH22_EM:AC000097.GENSCAN.121-3   2.11   PRSC_log, PRSC_con, RPWE-2       333140           CH22_FGENES.84_1   2.11   HT29, NCI-H69, OVCA-R       315081   AI247134   Hs.155281   ESTs   2.11   MB-MDA-453, MCF7, HT29       302965   AA446441   Hs.138842   ESTs   2.11   NCI-358, NCI-H23, CALU6       302138   N83965       EST   2.11   PRSC_log, PRSC_con, NCI-H345       320802   D83824   Hs.185055   BENE protein   2.11   A549, PC3, HT29       322152   AA565332       EST cluster (not in UniGene)   2.11   A549, CALU6, EB       326418           CH.19_hs gi|5867365   2.1   EB, OVCA-R, DU145       308709   AI783498   Hs.181165   eukaryotic translation elongation factor   2.1   MB-MDA-435s, MB-MDA-453, DU145       332737   C01852   Hs.84359   hypothetical protein   2.1   NCI-H23, A549, DU145       333283           CH22_FGENES.128_13   2.1   NCI-H345, RPWE-2, PRSC_con       328636           CH.07_hs gi|6004473   2.1   DU145, EB, MB-MDA-453       329187           CH.X_hs gi|5868713   2.1   NCI-358, NCI-H23, NCI-H460       305999   AA889603       EST singleton (not in UniGene) with exon   2.1   HT29, OVCA-R, PC3       333220           CH22_FGENES.104_12   2.1   PRSC_con, PRSC_log, RPWE-2       335092           CH22_FGENES.492_2   2.1   NCI-H69, PRSC_con, NCI-H345       304887   AA599355       EST singleton (not in UniGene) with exon   2.1   DU145, EB, MCF7       325359           CH.12_hs gi|5866920   2.1   MB-MDA-453, EB, MB-MDA-435s       330956   H08730   Hs.6933   ESTs   2.1   NCI-H520, PRSC_con, NCI-H345       323786   AW449315   Hs.165795   ESTs   2.1   OVCA-R, A549, LnCap       333619           CH22_FGENES.219_3   2.1   BT474, OVCA-R, HT29       324538   AW502979       EST cluster (not in UniGene)   2.09   CALU6, A549, DU145       303405   AA308601       EST   2.09   DU145, CALU6, NCI-H69       328570           CH.07_hs gi|5868231   2.09   LnCap, MB-MDA-231, DU145       308971   AI871218   Hs.224731   EST   2.09   NCI-H23, NCI-H460, NCI-358       330467   K02268   Hs.22584   prodynorphin   2.09   PC3, BT474, MB-MDA-453       334793           CH22_FGENES.433_5   2.09   EB, DU145, LnCap       300908   AA618335   Hs.146137   ESTs; Weakly similar to putative [ C.eleg     2.09   NCI-H345, PRSC_log, PRSC_con       309656   AW197060   Hs.195188   glyceraldehyde-3-phosphate dehydrogenase   2.09   A549, NCI-H23, NCI-H460       320963   AB029041   Hs.209646   KIAA1118 protein   2.09   PRSC_con, PRSC_log, NCI-H345       310833   AW295351   Hs.169136   ESTs   2.09   PC3, LnCap, MB-MDA-453       335693           CH22_FGENES.596_8   2.09   NCI-H69, LnCap, PRSC_log       325966           CH.16_hs gi|5867147   2.09   MCF7, CALU6, MB-MDA-453       329319           CH.X_hs gi|6381976   2.09   NCI-H460, EB, DU145       338526           CH22_EM:AC005500.GENSCAN.396-14   2.09   NCI-H69, NCI-H345, PRSC_log       336751           CH22_FGENES.128-5   2.09   NCI-H69, NCI-H345, PRSC_log       325510           CH.12_hs gi|5866974   2.09   HT29, OVCA-R, CALU6       323553   AA292626   Hs.122854   ESTs   2.08   NCI-H345, RPWE-2, NCI-358       326343           CH.17_hs gi|8525295   2.08   EB, LnCap, DU145       335470           CH22_FGENES.568_3   2.08   NCI-H69, PRSC_con, PRSC_log       320122   T93681   Hs.187515   ESTs   2.08   MCF7, MB-MDA-453, BT474       335320           CH22_FGENES.534_7   2.08   BT474, MB-MDA-231, HT29       307120   AI184343       EST singleton (not in UniGene) with exon   2.08   HT29, MCF7, PC3       338080           CH22_EM:AC005500.GENSCAN.172-11   2.08   LnCap, PC3, HT29       313113   AI056258   Hs.122523   ESTs   2.08   MCF7, DU145, MB-MDA-453       337685           CH22_EM:AC000097.GENSCAN.77-1   2.08   NCI-H69, NCI-H345, PRSC_log       327461           CH.02_hs gi|6004455   2.08   NCI-H23, BT474, NCI-358       335895           CH22_FGENES.635_3   2.08   HT29, MB-MDA-231, NCI-H520       303933   AW471472       EST singleton (not in UniGene) with exon   2.08   MS-MDA-231, BT474, NCI-H345       314803   AI935159   Hs.166841   ESTs; Weakly similar to MYOSIN LIGHT CHA   2.08   PC3, A549, BT474                   NON-MUSCLE ISOZYMES [ H.sapiens ]       302722   U53530       EST   2.08   DU145, MB-MDA-435s, OVCA-R       307703   AI318588       EST singleton (not in UniGene) with exon   2.08   HT29, MB-MDA-435s, CALU6       310558   AI334965   Hs.176976   ESTs   2.08   A549, LnCap, PC3       315276   AA860090       EST cluster (not in UniGene)   2.08   PC3, MCF7, OVCA-R       306443   AA976950       EST singleton (not in UniGene) with exon   2.07   OVCA-R, PC3, EB       307961   AI421059       EST singleton (not in UniGene) with exon   2.07   HT29, OVCA-R, CALU6       329735           CH.14_p2 gi|6065780   2.07   EB, HT29, OVCA-R       335193           CH22_FGENES.507_8   2.07   EB, A549, A549       320347   R34423   Hs.221535   ESTs   2.07   CALU6, A549, EB       316153   AA724474   Hs.147208   ESTs   2.07   MS-MDA-453, PC3, HT29       300921   AW293224   Hs.232165   ESTs   2.07   HT29, CALU6, CALU6       319264   T65096       EST cluster (not in UniGene)   2.07   MS-MDA-453, MCF7, CALU6       330204           CH.05_p2 gi|6013606   2.07   OVCA-R, DU145, EB       317070   AI142037   Hs.125379   ESTs   2.07   PRSC_con, NCI-H345, OVCA-R       337645           CH22.EM:AC000097.GENSCAN.10-8   2.07   NCI-H345, PRSC_log, NCI-H69       312501   AW450490   Hs.132886   ESTs   2.07   NCI-H520, CALU6, MCF7       335587           CH22_FGENES.581_26   2.07   NCI-H69, NCI-H345, PRSC_log       311482   AI917706   Hs.129997   ESTs   2.07   NCI-H520, MCF7, MS-MDA-435s       302488   AF161441       EST   2.07   EB, DU145, CALU6       304692   AA554202   Hs.76067   heat shock 27 kD protein 1   2.07   MCF7, MB-MDA-453, PC3       325369           CH.12_hs gi|5866920   2.07   DU145, DU145, MS-MDA-453       306284   AA936835       EST singleton (not in UniGene) with exon   2.07   BT474, MB-MDA-231, HT29       337402           CH22_FGENES.752-1   2.07   A549, BT474, DU145       327418           CH.02_hs gi|5867750   2.07   MCF7, MB-MDA-453, MB-MDA-435s       317977   AI004775   Hs.205091   ESTs; Weakly similar to WW domain bindin   2.07   BT474, MB-MDA-453, PC3       331870   AA428560   Hs.161845   EST   2.07   MB-MDA-231, MB-MDA-435s, BT474       300750   AA514805   Hs.105464   ESTs   2.07   HT29, BT474, BT474       336657           CH22_FGENES.35-14   2.07   MB-MDA-453, MCF7, NCI-H460       336035           CH22_FGENES.678_6   2.07   NCI-H69, PRSC_con, RPWE-2       325320           CH.11_hs gi|5866870   2.06   NCI-H69, PRSC_log, PRSC_con       306053   AA905312       EST singleton (not in UniGene) with exon   2.06   HT29, OVCA-R, MB-MDA-231       333175           CH22_FGENES.95_2   2.06   LnCap, HT29, DU145       304491   AA437096   Hs.115502   EST   2.06   MB-MDA-435s, CALU6, CALU6       310632   AI697536   Hs.176991   ESTs   2.06   NCI-H69, PRSC_log, NCI-H345       338521           CH22_EMAC005500.GENSCAN.395-35   2.06   NCI-H345, PRSC_log, PRSC_log       334900           CH22_FGENES.452_14   2.06   A549, CALU6, NCI-H69       337451           CH22_FGENES.774-2   2.06   PRSC_con, PRSC_log, RPWE-2       306792   AI815153   Hs.195188   glyceraldehyde-3-phosphate dehydrogenase   2.06   DU145, BT474, MB-MDA-453       336854           CH22_FGENES.280-1   2.06   LnCap, EB, MB-MDA-435s       304485   AA434076       EST singleton (not in UniGene) with exon   2.06   MB-MDA-231, BT474, CALU6       326458           CH.19_hs gi|5867400   2.06   EB, DU145, LnCap       303506   AA340605   Hs.105887   ESTs   2.06   LnCap, MCF7, CALU6       333628           CH22_FGENES.226_2   2.06   NCI-H520, NCI-358, NCI-358       300763   AA190753       EST   2.06   NCI-H69, NCI-H345, PRSC_con       334836           CH22_FGENES.439_6   2.06   NCI-H345, PRSC_con, RPWE-2       335217           CH22_FGENES.512_3   2.06   PRSC_log, PRSC_con, NCI-H69       338970           CH22_DJ32I10.GENSCAN.26-3   2.06   A549, MB-MDA-453, LnCap       334842           CH22_FGENES.439_21   2.06   DU145, HT29, CALU6       309309   AW006428   Hs.232857   EST   2.06   EB, DU145, OVCA-R       332949           CH22_FGENES.47_12   2.06   EB, DU145, OVCA-R       310530   AW369663   Hs.150150   ESTs   2.06   PRSC_con, PRSC_log, RPWE-2       329401           CH.X_hs gi|6682544   2.06   NCI-H69, PRSC_con, RPWE-2       316893   AA837332       EST duster (not in UniGene)   2.06   OVCA-R, MCF7, MR-MDA-453       325022   W95840   Hs.59745   NADH dehydrogenase (ubiquinone) flavopro   2.06   Caco2, NCI-358, OVCA-R       329839           CH.14_p2 gi|6672062   2.05   MB-MDA-231, RPWE-2, CALU6       306668   AI004890       EST singleton (not in UniGene) with exon   2.05   DU145, MB-MDA-453, MCF7       315604   AW137442   Hs.136965   ESTs   2.05   LnCap, EB, PC3       318551   AI909951   Hs.239307   tyrosyl-tRNA synthetase   2.05   NCI-H345, PRSC_con, RPWE-2       339344           CH22_BA354I12.GENSCAN.28-1   2.05   BT474, MR-MDA-231, A549       310621   AI632098   Hs.198099   ESTs   2.05   NCI-H69, RPWE-2, MCF7       327051           CH.21_hs gi|6531965   2.05   PRSC_con, NCI-H345, PRSC_log       336827           CH22_FGENES.236-2   2.05   NCI-H345, A549, MB-MDA-231       311846   AI078033   Hs.177170   ESTs; Moderately similar to !!!! ALU SUB   2.05   OVCA-R, DU145, CALU6       335036           CH22_FGENES.475_14   2.05   NCI-H69, PRSC_con, NCI-H345       313100   N52880   Hs.122817   ESTs   2.05   RPWE-2, NCI-H345, PRSC_log       301927   AF014459   Hs.113250   retinoschisis (X-linked; juvenile) 1   2.05   MB-MDA-231, NCI-H345, PRSC_con       326070           CH.17_hs gi|5867175   2.05   MB-MDA-435s, MB-MDA-231, BT474       338514           CH22_EM:AC005500.GENSCAN.392-4   2.05   PRSC_con, PRSC_log, RPWE-2       328098           CH.06_hs gi|5868020   2.05   DU145, CALU6, EB       301102   AA679361   Hs.249487   ESTs   2.05   NCI-H460, PRSC_con, NCI-H23       306193   AA923457       EST singleton (not in UniGene) with exon   2.05   NCI-H345, PRSC_con, RPWE-2       317027   AA883808   Hs.174148   ESTs   2.05   EB, DU145, CALU6       336102           CH22_FGENES.693_2   2.04   LnCap, NCI-H69, PRSC_log       301372   AI239895   Hs.130555   ESTs   2.04   PRSC_con, RPWE-2, PRSC_log       333252           CH22_FGENES.116_4   2.04   NCI-358, A549, HT29       322516   AW372340   Hs.159717   ESTs   2.04   HT29, MB-MDA-231, BT474       324146   AA393624       EST cluster (not in UniGene)   2.04   RPWE-2, PRSC_con, MB-MDA-231       338770           CH22_EM:AC005500.GENSCAN.520-1   2.04   PRSC_con, NCI-H69, NCI-H460       314795   AI798611   Hs.157277   ESTs   2.04   EB, PC3, LnCap       333004           CH22_FGENES.60_1   2.04   A549, NCI-358, DU145       302405   AW245825   Hs.211914   NADH dehydrogenase (ubiquinone) Fe-S pro   2.04   NCI-H520, CALU6, Caco2       323587   AI905527   Hs.141901   ESTs; Moderately similar to !!!! ALU SUB   2.04   EB, A549, HT29       300898   AI276278   Hs.157176   ESTs   2.04   PC3, MR-MDA-453, BT474       301506   AI149878   Hs.143519   ESTs; Weakly similar to testicular tekti   2.04   NCI-H69, RPWE-2, NCI-H345       325851           CH.16_hs gi|5867067   2.04   MB-MDA-231, HT29, EB       323945   AI125604   Hs.155117   ESTs   2.04   MCF7, DU145, DU145       303265   AW160951       EST   2.04   LnCap, OVCA-R, DU145       334135           CH22_FGENES.336_2   2.04   PC3, A549, MB-MDA-435s       329793           CH.14_p2 gi|8522661   2.04   DU145, CALU6, HT29       332595   AA256431   Hs.3244   G protein pathway suppressor 2   2.04   A549, CALU6, NCI-H23       316059   AW166388   Hs.250181   ESTs   2.04   MCF7, HT29, A549       324104   AW248071   Hs.133122   ESTs   2.04   Caco2, A549, MCF7       306801   AI052653       EST singleton (not in UniGene) with exon   2.03   EB, LnCap, PC3       338096           CH22.EM:AC005500.GENSCAN.181-14   2.03   DU145, HT29, CALU6       327544           CH.03_hs gi|5867797   2.03   PRSC_con, NCI-H69, NCI-H345       318813   F13195       EST cluster (not in UniGene)   2.03   PRSC_con, RPWE-2, PRSC_log       325289           CH.11_hs gi|5866903   2.03   EB, OVCA-R, A549       311099   T56361   Hs.182167   hemoglobin: gamma A   2.03   HT29, RT474, EB       316079   AA922213   Hs.121735   ESTs   2.03   LnCap, OVCA-R, EB       309533   AW151131       EST singleton (not in UniGene) with exon   2.03   MB-MDA-231, BT474, LnCap       338579           CH22.EM:AC005500.GENSCAN.431-3   2.03   NCI-H69, NCI-H345, RPWE-2       326549           CH.19_hs gi|5867307   2.03   NCI-H69, Caco2, NCI-H345       320012   AI628384   Hs.193745   ESTs   2.03   BT474, MB-MDA-453, MCF7       334111           CH22_FGENES.330_10   2.03   NCI-H69, MB-MDA-231, BT474       327123           CH.21_hs gi|6531971   2.03   NCI-H345, NCI-H69, RPWE-2       324568   AW502311       EST cluster (not in UniGene)   2.03   NCI-H345, NCI-H520, NCI-H460       306012   AA896989       EST singleton (not in UniGene) with exon   2.03   NCI-H69, PRSC_log, PRSC_con       303106   AA012877       EST   2.03   RPWE-2, OVCA-R, EB       302194   U52219   Hs.158329   G protein-coupled receptor 50   2.03   NCI-H520, NCI-H23, PC3       326646           CH.20_hs gi|5867562   2.03   NCI-H460, OVCA-R, HT29       304060   T61464       EST singleton (not in UniGene) with exon   2.03   NCI-H345, PRSC_con, PRSC_log       304667   AA535602       EST singleton (not in UniGene) with exon   2.03   A549, DU145, EB       330514   M83652   Hs.53155   properdin P factor, complement   2.02   NCI-H23, NCI-H460, NCI-358       310324   AI473273   Hs.159674   ESTs; Weakly similar to GLUTAMATE [ H.sap     2.02   NCI-H345, MB-MDA-231, BT474       330327           CH.08_p2 gi|5919194   2.02   NCI-H345, NCI-H69, PRSC_log       308447   AI659985       EST singleton (not in UniGene) with exon   2.02   NCI-H345, RPWE-2, PRSC_log       307778   AI344972   Hs.231496   EST   2.02   NCI-H69, CALU6, OVCA-R       319459   T87351   Hs.194121   ESTs   2.02   NCI-H460, NCI-358, NCI-H520       300935   AA513644   Hs.222815   ESTs; Weakly similar to Wiskott-Aldrich   2.02   DU145, EB, OVCA-R       314318   AL037405   Hs.176141   ESTs   2.02   PRSC_con, LnCap, PRSC_log       334779           CH22_FGENES.432_1   2.02   EB, HT29, DU145       336994           CH22_FGENES.410-2   2.02   NCI-H345, PRSC_con, NCI-H69       334076           CH22_FGENES.327_31   2.02   OVCA-R, CALU6, EB       318116   AW452865   Hs.132339   ESTs   2.02   MB-MDA-231, NCI-H69, NCI-H345       326783           CH.20_hs gi|6525298   2.02   NCI-H69, PRSC_con, RPWE-2       336142           CH22_FGENEB.705_4   2.02   NCI-H69, PRSC_log, PRSC_con       320913   AA663733       EST cluster (not in UniGene)   2.02   DU145, EB, CALU6       301644   AW239364       EST   2.02   PRSC_con, RPWE-2, PRSC_log       300944   AW081072   Hs.164624   ESTs; Weakly similar to Slit-3 protein [   2.01   RPWE-2, NCI-H69, NCI-H23       310080   AW137088   Hs.144857   ESTs   2.01   PRSC_con, NCI-H345, PRSC_log       311246   AI863918   Hs.195078   ESTs   2.01   NCI-H345, NCI-H69, RPWE-2       319207   R87679       EST cluster (not in UniGene)   2.01   HT29, A549, NCI-H460       334760           CH22_FGENES.428_9   2.01   NCI-358, NCI-H69, PRSC_log       338368           CH22_EM:AC005500.GENSCAN.325-2   2.01   NCI-H23, NCI-H520, NCI-H460       317300   AI417007   Hs.166338   ESTs   2.01   NCI-H460, DU145, NCI-H23       323699   AW178750       EST cluster (not in UniGene)   2.01   MCF7, MB-MDA-453, OVCA-R       301366   AA907713   Hs.221667   ESTs   2.01   PRSC_con, NCI-H345, RPWE-2       333306           CH22_FGENES.137_3   2.01   NCI-H69, NCI-H345, PRSC_con       328031           CH.06_hs gi|5902482   2.01   MB-MDA-231, NCI-H345, PRSC_con       301806   AA326007   Hs.12056   asialoglycoprotein receptor 1   2.01   MB-MDA-453, DU145, EB       300993   AA584930   Hs.191777   ESTs; Weakly similar to XAP-5-like prote   2.01   HT29, NCI-H23, NCI-358       320042   T84520       EST cluster (not in UniGene)   2.01   PRSC_con, NCI-H345, NCI-H69       331082   R17059   Hs.22100   ESTs   2.01   EB, DU145, MB-MDA-435s       308851   AI829820       EST singleton (not in UniGene) with exon   2.01   DU145, EB, PC3       301163   AA732066       EST   2.01   OVCA-R, PC3, MB-MDA-435s       304734   AA576428       EST singleton (not in UniGene) with exon   2.01   LnCap, MB-MDA-453, DU145       334855           CH22_FGENES.442_6   2.01   NCI-H345, RPWE-2, PRSC_log       337121           CH22_FGENES.519-1   2.01   NCI-H69, NCI-H345, PRSC_con       331838   AA412498   Hs.104778   ESTs   2.01   BT474, BT474, MCF7       339181           CH22_DA59H18.GENSCAN.72-6   2.01   NCI-H345, PRSC_con, NCI-H69       327564           CH.03_hs gi|5867811   2.01   BT474, HT29, DU145       304108   R63932   Hs.28467   EST   2   BT474, OVCA-R, MCF7       315036   AA534953   Hs.163297   ESTs   2   MB-MDA-435s, MB-MDA-453, LnCap       312777   W92809   Hs.138557   ESTs   2   PRSC_con, NCI-H345, MB-MDA-231       305888   AA868536   Hs.126145   EST   2   HT29, HT29, BT474       323185   R52177       EST cluster (not in UniGene)   2   EB, A549, BT474       308681   AI761307       EST singleton (not in UniGene) with exon   2   RPWE-2, PRSC_con, NCI-H345       325755           CH.14_hs gi|6682474   2   NCI-H345, PRSC_con, PRSC_log       324376   AW499705       EST cluster (not in UniGene)   2   DU145, BT474, PC3       331890   AA432166   Hs.3577   succinate dehydrogenase complex; subunit   2   CALU6, MB-MDA-453, A549                    
     [0330]               TABLE 4                          Pkey: Unique Eos probeset identifier number       ExAccn: Exemplar Accession number, Genbank accession number       UnigeneID: Unigene number       Unigene Title: Unigene gene title                                                     Ratio           Pkey   Exr_Accn   UniG_ID   Complete_Title   Met/BS   Top 3 expressing cell lines                                                                         313166   AI801098   Hs.151500   ESTs   12.23   Caco2, EB, OVCA-R       334593           CH22_FGENES.408_3   8.06   NCI-H169, OVCA-R, OVCA-R       331084   R20655   Hs.81281   Human clone 23732 mRNA; partial cds   7.89   LnCap, OVCA-R, EB       324598   AA502659   Hs.163986   ESTs   7.77   OVCA-R, EB, CALU6       314071   AA192455   Hs.188690   ESTs   7.76   CALU6, EB, DU145       315178   AW362945   Hs.162459   ESTs   6.81   OVCA-R, EB, CALU6       325519           CH.12_hs gi|6017036   6.34   NCI-H69, NCI-H345, PRSC_con       331433   H68097   Hs.161023   EST   6.16   OVCA-R, A549, EB       315021   AA533447       EST cluster (not in UniGene)   6.15   PC3, EB, CALU6       337695           CH22_EM:AC000097.GENSCAN.84-1   5.84   NCI-H69, NCI-H345, DU145       324048   AA378739       EST cluster (not in UniGene)   5.77   OVCA-R, DU145, EB       300781   AA731209       EST cluster (not in UniGene) with exon h   5.72   MB-MDA-453, MCF7, MB-MDA-435s       320701   AI093177   Hs.134923   ESTs   5.68   A549, NCI-H345, NCI-H69       332471   AA416967   Hs.120980   nuclear receptor co-repressor 2   5.68   LnCap, A549, OVCA-R       331858   AA421163   Hs.163848   ESTs   5.66   OVCA-R, DU145, Caco2       330987   H40988   Hs.131965   ESTs   5.35   NCI-H345, OVCA-R, LnCap       322309   AF086372       EST cluster (not in UniGene)   5.31   OVCA-R, DU145, PC3       324733   AA582082   Hs.199410   ESTs   5.17   PRSC_con, PRSC_log, NCI-H345       313577   AA565051   Hs.155029   ESTs   5.16   OVCA-R, PC3, EB       310966   AW271974   Hs.210295   ESTs   5.15   NCI-H69, PRSC_log, PRSC_con       311332   AW292247   Hs.255052   ESTs   5.05   Caco2, OVCA-R, EB       314522   AI732331   Hs.187750   ESTs; Moderately similar to !!!! ALU CLA   5.04   EB, DU145, HT29       330886   AA135606   Hs.189384   ESTs; Weakly similar to !!!! ALU SUBFAMI   4.93   OVCA-R, DU145, Caco2       313597   AW162263   Hs.249990   ESTs   4.84   NCI-H460, NCI-H345, NCI-H23       314439   AI539443   Hs.137447   ESTs   4.84   DU145, Caco2, MB-MDA-231       320807   AA086110   Hs.188536     H sapiens  clone 24838 mRNA seq   4.83   PC3, OVCA-R, DU145       311804   AA135159   Hs.203349   ESTs   4.82   OVCA-R, PC3, Caco2       321354   AA078493       EST cluster (not in UniGene)   4.81   DU145, EB, OVCA-R       325169   H01560   Hs.163818   ESTs; Weakly similar to !!!! ALU SUBFAMI   4.8   NCI-H345, DU145, LnCap       312828   AI865455   Hs.211818   ESTs; Moderately similar to !!!! ALU SUB   4.78   DU145, DU145, DU145       321226   AA311443   Hs.251416     H sapiens  mRNA; cDNA DKFZp586E2317 (from   4.75   DU145, OVCA-R, MB-MDA-453       327772           CH.05_hs gi|5867964   4.74   HT29, MB-MDA-231, NCI-H345       315642   AA742222   Hs.120634   ESTs   4.7   DU145, EB, MB-MDA-453       311905   AA555215   Hs.151913   ESTs   4.7   DU145, Caco2, PRSC_con       312754   R99834   Hs.250383   ESTs   4.59   OVCA-R, PC3, EB       336637           CH22_FGENES.13-7   4.58   NCI-H69, PRSC_log, NCI-H345       331644   T99544   Hs.173734   ESTs; Weakly similar to !!!! ALU CLASS B   4.55   OVCA-R, NCI-H345, Caco2       336984           CH22_FGENES.401-2   4.55   Caco2, Caco2, EB       316261   AW134485   Hs.144967   ESTs   4.53   NCI-H460, NCI-H345, Caco2       300417   AW139492   Hs.245887   ESTs   4.52   DU145, CALU6, EB       300610   N72596   Hs.99120   DEAD/H (Asp-Glu-Ala-Asp/His) box polypep   4.52   OVCA-R, PC3, EB       324718   AI557019   Hs.116467   ESTs   4.5   LnCap, PC3, PRSC_con       332170   F04112   Hs.177178   ESTs   4.47   Caco2, DU145, DU145       324042   AA377589       EST cluster (not in UniGene)   4.45   NCI-H345, PRSC_con, PRSC_log       331148   R73816   Hs.17385   ESTs   4.44   CALU6, OVCA-R, EB       328981           CH.09_hs gi|5868527   4.43   HT29, BT474, NCI-H69       321920   N63915       EST cluster (not in UniGene)   4.34   Caco2, A549, A549       320832   AA214584       EST cluster (not in UniGene)   4.34   NCI-H23, CALU6, OVCA-R       321971   AI680459   Hs.201441   ESTs   4.33   DU145, HT29, CALU6       308572   AI707882       EST singleton (not in UniGene) with exon   4.33   MCF7, NCI-H345, OVCA-R       302459   AF169255       EST cluster (not in UniGene) with exon h   4.28   MB-MDA-231, OVCA-R, LnCap       321847   T08401       EST cluster (not in UniGene)   4.25   MB-MDA-453, MB-MDA-435s, MBS-MDA-231       337884           CH22_EM:AC005500.GENSCAN.54-2   4.23   HT29, NCI-H23, MB-MDA-435s       307494   AI269188   Hs.175656   EST   4.23   NCI-H23, NCI-H520, NCI-358       314915   AA573072   Hs.187748   ESTs; Weakly similar to !!!! ALU SUSFAMI   4.21   PC3, OVCA-R, Caco2       336638           CH22_FGENES.14-2   4.21   NCI-H69, NCI-H345, PRSC_log       319379   T91443   Hs.193963   ESTs   4.2   PC3, OVCA-R, LnCap       312332   R33041   Hs.106200   ESTs   4.19   NCI-H69, OVCA-R, NCI-H460       331445   H89093   Hs.41215   ESTs   4.19   EB, HT29, DU145       315841   AW138397   Hs.247572   ESTs   4.19   Caco2, MB-MDA-453, LnCap       315712   AI950133   Hs.120882   ESTs; Moderately similar to !!!! ALU SUB   4.18   LnCap, NCI-H345, OVCA-R       319559   AA773876   Hs.251597   ESTs   4.15   NCI-H345, Caco2, DU145       300791   AL138455   Hs.256135   ESTs; Moderately similar to !!!! ALU SUB   4.13   NCI-358, RPWE-2, NCI-H460       312129   AW300867       EST cluster (not in UniGene)   4.12   OVCA-R, MCF7, A549       321166   AA411263   Hs.128783   ESTs   4.11   QVCA-R, Caco2, PRSC_con       313220   AI971981   Hs.118241   ESTs   4.1   OVCA-R, DU145, Caco2       314022   AW452420   Hs.248678   ESTs   4.1   OVCA-R, EB, PC3       321359   AW474412       EST cluster (not in UniGene)   4.1   DU145, OVCA-R, PC3       328841           CH.07_hs gi|6381920   4.09   NCI-H69, PRSC_log, NCI-H345       337898           CH22_EM:AC005500.GENSCAN.56-5   4.09   NCI-H345, NCI-H69, OVCA-R       333245           CH22_FGENES.115_2   4.09   PRSC_log, PRSC_con, NCI-H345       311958   AI247472   Hs.132965   ESTs   4.06   EB, DU145, CALU6       314775   AI149880   Hs.188809   ESTs   4.06   OVCA-R, PC3, EB       317901   AW150944   Hs.250541   ESTs   4.06   BT474, MB-MDA-453, MB-MDA-435s       309985   AW452919       EST singleton (not in UniGene) with exon   4.05   MB-MDA-453, NCI-H23, NCI-H520       311004   AA632846       EST cluster (not in UniGene)   4.05   MB-MDA-453, OVCA-R, EB       323497   AI523613   Hs.221544   ESTs   4.04   LnCap, OVCA-R, EB       332347   W60326   Hs.221716   ESTs   4.04   EB, CALU6, PC3       331388   AA456852   Hs.43543   suppressor of whhe apricot homolog 2   4.01   A549, EB, Caco2       313197   AI738851   Hs.222487   ESTs   3.96   OVCA-R, EB, PC3       315710   AA931550   Hs.192785   ESTs   3.95   EB, MB-MDA-231, OVCA-R       316897   AA838114       EST cluster (not in UniGene)   3.94   OVCA-R, A549, MB-MDA-453       322564   W86440   Hs.118344   ESTs   3.94   NCI-H460, Caco2, EB       304605   AA513225       EST singleton (not in UniGene) with exon   3.9   NCI-H345, RPWE-2, BT474       325726           CH.14_hs gi|6552447   3.9   OVCA-R, LnCap, LnCap       320190   R32047   Hs.141012   ESTs; Weakly similar to !!!! ALU SUBFAMI   3.89   DU145, NCI-H23, PRSC_log       331566   N63062   Hs.48703   EST   3.87   NCI-H23, NCI-H460, NCI-358       319403   T98413       EST cluster (not in UniGene)   3.86   NCI-H345, PRSC_log, LnCap       324643   AI436356   Hs.130729   ESTs   3.84   OVCA-R, DU145, NCI-H345       315298   AI969314   Hs.211377   ESTs   3.82   NCI-H345, PRSC_con, PRSC_log       321632   AA419617       EST cluster (not in UniGene)   3.81   EB, OVCA-R, A549       313219   N74924   Hs.182099   ESTs   3.8   EB, Caco2, OVCA-R       330833   AA046804       ESTs; Weakly similar to !!!! ALU SUBFAMI   3.8   LnCap, DU145, PC3       327289           CH.01_hs gi|5867481   3.79   EB, HT29, DU145       314429   AW300749       EST cluster (not in UniGene)   3.79   OVCA-R, PC3, PRSC_con       314475   AI911160   Hs.127505   ESTs   3.79   DU145, CALU6, NCI-H69       317130   AW293995   Hs.192277   ESTs   3.78   EB, PC3, Caco2       336635           CH22_FGENES.13-5   3.77   NCI-H69, NCI-H345, PRSC_log       333323           CH22_FGENES.138_16   3.76   NCI-H460, NCI-H23, PRSC_con       332135   AA620331   Hs.245351   EST   3.75   NCI-H345, A549, Caco2       316979   AA861087       EST cluster (not in UniGene)   3.75   NCI-H345, NCI-H69, RPWE-2       316435   AI671871   Hs.192618   ESTs; Weakly similar to !!!! ALU CLASS C   3.74   MB-MDA-435s, MCF7, MB-MDA-453       316422   AW135357   Hs.192374   ESTs   3.73   OVCA-R, A549, EB       336616           CH22_FGENES.613_5   3.72   NCI-H69, NCI-H345, RPWE-2       320258   W93241       EST cluster (not in UniGene)   3.71   MB-MDA-231, NCI-H69, EB       300463   N52510   Hs.186470   ESTs   3.69   OVCA-R, A549, DU145       306881   AI088695       EST singleton (not in UniGene) with exon   3.68   CALU6, HT29, EB       337304           CH22_FGENES.681-6   3.67   MCF7, MB-MDA-453, LnCap       323693   AW297758   Hs.249721   ESTs   3.67   OVCA-R, MB-MDA-453, DU145       331073   R07998   Hs.18628   ESTs; Weakly similar to !!!! ALU SUBFAMI   3.67   RPWE-2, NCI-H345, OVCA-R       318162   AW296277   Hs.132171   ESTs   3.67   MB-MDA-231, DU145, CALU6       318042   AW294522   Hs.149991   ESTs   3.66   ES, HT29, CALU6       308069   AI470895       EST singleton (not in UniGene) with exon   3.64   Caco2, Caco2, NCI-H23       327614           CH.04_hs gi|6525283   3.62   NCI-H460, NCI-H345, NCI-H69       337514           CH22_FGENES.809.7   3.62   NCI-358, NCI-H23, NCI-H460       332093   AA608794   Hs.112592   ESTs   3.6   EB, OVCA-R, DU145       327793           CH.05_hs gi|5867979   3.59   LnCap, OVCA-R, EB       331053   N70242   Hs.183146   ESTs   3.59   OVCA-R, EB, Caco2       303769   AA134888   Hs.173415   ESTs   3.58   HT29, CALU6, CALU6       319872   R97130   Hs.189699   ESTs   3.58   PRSC_con, LnCap, RPWE-2       317902   AI828602   Hs.211265   ESTs   3.57   CALU6, NCI-H345, OVCA-R       324090   AI656531   Hs.116070   ESTs   3.57   PRSC_con, NCI-H345, PRSC_log       300120   AW204314   Hs.170784   ESTs   3.57   NCI-H69, NCI-H345, PRSC_con       307752   AI339447       EST singleton (not in UniGene) with exon   3.56   NCI-358, HT29, MB-MDA-231       322438   W44531   Hs.167851   ESTs   3.55   NCI-H345, NCI-H69, Caco2       311275   AI659166   Hs.207144   ESTs   3.55   MB-MDA-231, PRSC_con, LnCap       338830           CH22_DJ246D7.GENSCAN.6-7   3.54   LnCap, PC3, OVCA-R       315647   AA648983   Hs.212911   ESTs   3.53   OVCA-R, MB-MDA-453, CALU6       331469   N22273   Hs.39140   ESTs   3.52   EB, A549, CALU6       313445   AI123657   Hs.127264   ESTs   3.51   EB, OVCA-R, A549       330139           CH.21_432 gi|4210430   3.5   EB, CALU6, DU145       304450   AA404521   Hs.10326   coatomer protein complex: subunit epsilo   3.49   NCI-H345, NCI-H69, NCI-H460       325763           CH.14_hs gi|6682475   3.49   PC3, BT474, OVCA-R       312803   AA677934   Hs.117864   ESTs   3.47   OVCA-R, Caco2, MB-MDA-453       303654   AA436942   Hs.168308   ESTs   3.46   DU145, NCI-H460, NCI-H69       317924   AI222324   Hs.166306   ESTs; Weakly similar to zinc finger prot   3.46   PRSC_con, PRSC_log, NCI-H69       312354   AA036955   Hs.167040   ESTs   3.44   Caco2, MB-MDA-435s, NCI-H460       337517           CH22_FGENES.814-6   3.43   NCI-H69, HT29, PC3       324865   AA702138   Hs.114103   ESTs   3.42   NCI-H23, NCI-H460, NCI-H520       323755   AW300094       EST cluster (not in UniGene)   3.42   PRSC_con, RPWE-2, NCI-H345       314452   AL042699   Hs.209222   ESTs   3.42   NCI-H345, PRSC_con, PRSC_log       337911           CH22_EM:AC0055500.GENSCAN.59-6   3.42   OVCA-R, PC3, HT29       318086   AI025499   Hs.132238   ESTs   3.41   CALU6, LnCap, OVCA-R       311859   AA704705   Hs.181044   ESTs; Weakly similar to Chain A: Human O   3.41   LnCap, MB-MDA-435s, A549                   Complexed With L-Canaline [ H. sapiens ]       314409   H15560   Hs.131833   ESTs   3.41   NCI-H69, LnCap, LnCap       323333   AA228883       EST cluster (not in UniGene)   3.41   Caco2, OVCA-R, NCI-H69       325690           CH.14_hs gi|5867021   3.4   HT29, CALU6, DU145       314539   AA398216   Hs.190092   ESTs   3.4   MB-MDA-231, BT474, EB       310567   AI691065   Hs.155780   ESTs   3.4   PRSC_con, NCI-H345, NCI-H69       330527   S77356       transcript ch21 = oligomycin sensitivity c   3.39   NCI-H23, Caco2, A549                   8 stomach cancer cell lines, mRNA, 262 n       314660   AA436007   Hs.188780   ESTs   3.39   OVCA-R, BT474, Caco2       321321   AB033072       EST cluster (not in UniGene)   3.39   NCI-358, EB, Caco2       323356   AA234009   Hs.188715   ESTs   3.38   DU145, CALU6, CALU6       328592           CH.07_ha gi|5868227   3.38   MCF7, NCI-358, MB-MDA-231       311116   AI631195   Hs.232193   ESTs   3.36   NCI-H520, NCI-H23, PRSC_log       323853   AA393460       EST cluster (not in UniGene)   3.36   DU145, EB, Caco2       327740           CH.05_hs gi|5867943   3.35   EB, LnCap, OVCA-R       326857           CH.20_hs gi|6552460   3.33   NCI-H69, MCF7, NCI-H345       317787   AW339612   Hs.249364   ESTs   3.31   NCI-H345, PRSC_con, PRSC_log       325760           CH.14_hs gi|6552449   3.3   EB, CALU6, HT29       337513           CH22_FGENES.809-4   3.29   LnCap, NCI-H23, NCI-H460       336606           CH22_FGENES.429_3   3.29   NCI-H69, A549, NCI-H23       322895   AW470295   Hs.192152   ESTs   3.29   DU145, Caco2, EB       314312   AA814971   Hs.257634   ESTs   3.29   RPWE-2, NCI-H69, NCI-H345       328224           CH.06_hs gi|5868101   3.28   DU145, NCI-H345, LnCap       336128           CH22_FGENES.701_16   3.27   BT474, NCI-H520, MB-MDA-231       332442   AA281323   Hs.4947   ESTs   3.27   Caco2, PC3, NCI-H345       302514   M14269       EST cluster (not in UniGene) with exon h   3.27   DU145, CALU6, NCI-H520       313749   AW450376   Hs.130803   ESTs   3.26   OVCA-R, NCI-H69, DU145       302891   AI681578   Hs.114164   ESTs   3.26   LnCap, NCI-H345, PRSC_log       334690           CH22_FGENES.420_3   3.25   NCI-H69, RPWE-2, PRSC_con       308676   AI761036       EST singleton (not in UniGene) with exon   3.25   DU145, MB-MDA-231, HT29       304254   AA046273   Hs.111334   ferritin; light polypeptide   3.24   OVCA-R, DU145, A549       311994   AA648314   Hs.13849   ESTs   3.24   NCI-H460, NCI-H23, MB-MDA-453       321020   AB023170   Hs.227850   KIAA0953 protein   3.24   EB, MCF7, MB-MDA-435s       316724   AA810788   Hs.123337   ESTs   3.23   DU145, OVCA-R, BT474       326942           CH.21_hs gi|6004446   3.22   HT29, BT474, NCI-H23       324824   AI826999   Hs.224624   ESTs   3.21   OVCA-R, MB-MDA-453, EB       320789   R78712       EST cluster (not in UniGene)   3.21   DU145, LnCap, EB       315070   AW131368   Hs.185736   ESTs   3.21   Caco2, NCI-358, NCI-H460       303794   AW241987   Hs.197025   ESTs   3.19   OVCA-R, PC3, LnCap       310237   AI884313   Hs.158906   ESTs   3.19   NCI-358, NCI-H345, MCF7       313960   AA130859       EST cluster (not in UniGene)   3.18   MB-MDA-231, HT29, BT474       336634           CH22_FGENES.13-4   3.18   NCI-H69, NCI-H345, BT474       301085   AA779058   Hs.190428   ESTs; Weakly similar to NG26 [ H. sapiens ]   3.17   NCI-H345, NCI-H345, NCI-358       313774   AW136836   Hs.144583   ESTs   3.17   Caco2, EB, OVCA-R       307177   AI188864       EST singleton (not in UniGene) with exon   3.17   EB, CALU6, CALU6       324025   AI174861   Hs.190623   ESTs   3.17   OVCA-R, DU145, PC3       313099   AI307359   Hs.128064   ESTs   3.17   MB-MDA-231, BT474, EB       305536   AA770682       EST singleton (not in UniGene) with exon   3.17   NCI-358, Caco2, HT29       331916   AA446131   Hs.124918   ESTs   3.17   EB, OVCA-R, Caco2       314912   AI431345   Hs.161784   ESTs   3.17   EB, BT474, MCF7       303388   AL039604       EST cluster (not in UniGene) with exon h   3.17   HT29, NCI-358, Caco2       332273   R05818   Hs.173830   ESTs   3.16   MCF7, DU145, EB       314697   AW088739   Hs.243770   ESTs   3.16   MB-MDA-453, DU145, MCF7       335344           CH22_FGENES.536_3   3.15   PRSC_log, NCI-H345, PRSC_con       326162           CH.17_hs gi|5867168   3.15   BT474, HT29, HT29       304467   AA424703       EST singleton (not in UniGene) with exon   3.15   NCI-H23, RPWE-2, NCI-H460       339340           CH22_BA354I12.GENSCAN.27-8   3.15   LnCap, OVCA-R, MB-MDA-453       325393           CH.12_hs gi|5866921   3.13   Caco2, NCI-H23, NCI-358       315367   AA732484   Hs.169399   ESTs   3.13   OVCA-R, EB, MB-MDA-453       307085   AI160868       EST singleton (not in UniGene) with exon   3.12   RPWE-2, PRSC_con, PRSC_log       313001   N29264   Hs.249591   ESTs; Moderately similar to !!!! ALU SUB   3.12   NCI-H345, OVCA-R, Caco2       307606   AI290006       EST singleton (not in UniGene) with exon   3.12   MB-MDA-231, HT29, NCI-H23       325710           CH.14_hs gi|6682473   3.09   NCI-H69, MB-MDA-453, BT474       313810   AA400079   Hs.257854   ESTs   3.09   EB, DU145, CALU6       335482           CH22_FGENES.570_11   3.09   NCI-H460, NCI-358, NCI-H23       326310           CH.17_hs gi|5867277   3.08   MCF7, MB-MDA-453, PC3       325742           CH.14_hs gi|6552448   3.08   NCI-H23, NCI-H460, HT29       312467   AI241809   Hs.75458   ribosomal protein L18   3.08   NCI-358, NCI-H23, NCI-H460       327309           CH.01_hs gi|6456757   3.07   NCI-H69, MB-MDA-435s, MB-MDA-435s       310583   AW205632   Hs.211198   ESTs   3.07   OVCA-R, A549, Caco2       322373   W25673   Hs.130829   ESTs   3.07   NCI-H69, PRSC_con, NCI-H345       324497   AW152624   Hs.136340   ESTs   3.06   NCI-H345, RPWE-2, PRSC_con       315095   AA831815   Hs.243788   ESTs   3.06   Caco2, DU145, EB       302445   N79647       EST cluster (not in UniGene) with exon h   3.05   OVCA-R, A549, NCI-H460       302842   AW383226   Hs.163834   ESTs; Highly similar to Chp [ R. norvegicu     3.05   A549, DU145, NCI-H23       317346   AA952875   Hs.221274   ESTs   3.04   BT474, HT29, HT29       334650           CH22_FGENES.417_17   3.04   MCF7, BT474, OVCA-R       306644   AI002913       EST singleton (not in UniGene) with exon   3.04   CALU6, MCF7, BT474       322682   AI110679       EST cluster (not in UniGene)   3.03   NCI-H345, RPWE-2, OVCA-R       311065   AW204582   Hs.224906   ESTs   3.03   PRSC_log, PRSC_con, NCI-H460       318623   AA355439   Hs.151547   ESTs   3.03   DU145, MB-MDA-435s, HT29       304978   AA617735       EST singleton (not in UniGene) with exon   3.03   CALU6, BT474, MB-MDA-435s       305554   AA774567   Hs.121774   EST   3.03   EB, NCI-H460, Caco2       302574   U66199   Hs.249165   fibroblast growth factor 11   3.03   HT29, DU145, PC3       336202           CH22_FGENES.719_6   3.02   NCI-H69, NCI-H23, NCI-H23       302893   AL117539   Hs.173515     H sapiens  mRNA; cDNA DKFZp586H021 (from   3.02   EB, DU145, CALU6       315166   AI343966   Hs.158528   ESTs   3.01   Caco2, EB, NCI-H69       335606           CH22_FGENES.582_3   3.01   NCI-H23, NCI-H520, NCI-H345       330058           CH.17_p2 gi|6634847   3.01   OVCA-R, HT29, LnCap       303179   AA071215       EST cluster (not in UniGene) with exon h   3.01   MCF7, RPWE-2, MB-MDA-453       307625   AI299617       EST singleton (not in UniGene) with exon   3   MB-MDA-231, LnCap, BT474       323074   AL119445   Hs.203213   ESTs   3   NCI-H23, NCI-H520, NCI-H460       336232           CH22_FGENES.736_7   3   HT29, BT474, MB-MDA-231       334915           CH22_FGENES.457_4   3   NCI-H345, PRSC_con, NCI-H69       329116           CH.X_hs gi|5868650   3   NCI-H69, PRSC_con, RPWE-2       333495           CH22_FGENES.168_5   3   OVCA-R, NCI-H169, NCI-H345       303756   AI738488   Hs.115838   ESTs   2.99   HT29, PRSC_con, DU145       332134   AA610123   Hs.139240   DKFZP564F1422 protein   2.99   EB, A549, MCF7       322916   AW367294   Hs.154091   ESTs   2.99   DU145, DU145, OVCA-R       318050   AI052093   Hs.133132   ESTs   2.99   NCI-H345, DU145, NCI-H520       301019   AI147356   Hs.98722   ESTs   2.99   NCI-358, NCI-H69, MB-MDA-435s       315213   AA587773   Hs.136494   ESTs   2.98   MB-MDA-231, BT474, LnCap       339251           CH22_BA354I12.GENSCAN.7-5   2.98   NCI-H69, PRSC_log, HT29       303835   T05645       EST cluster (not in UniGene) with exon h   2.97   BT474, NCI-H345, LnCap       300070   AI174603   Hs.256832   ESTs   2.97   DU145, A549, OVCA-R       320954   AB028953   Hs.204121   KIAA1030 protein   2.97   LnCap, DU145, PC3       327624           CH.04_hs gi|5867871   2.97   EB, DU145, LnCap       329029           CH.X_hs gi|6525302   2.96   NCI-H69, PRSC_log, LnCap       317040   AA868584   Hs.126154   ESTs   2.96   DU145, EB, LnCap       328016           CH.06_hs gi|5902482   2.96   NCI-H345, PRSC_con, DU145       312674   AI762475   Hs.151327   ESTs; Moderately similar to !!!! ALU SUB   2.96   OVCA-R, NCI-H69, NCI-H69       332301   R70253   Hs.127826   ESTs   2.96   OVCA-R, DU145, MB-MDA-231       300951   AI732374   Hs.105834   ESTs; Weakly similar to 25 kDa trypsin i   2.95   NCI-358, NCI-H460, Caco2       318226   AI078446   Hs.134125   ESTs   2.95   NCI-H460, NCI-H23, NCI-358       311349   AW292933   Hs.254110   ESTs   2.94   EB, DU145, OVCA-R       312757   AI285970   Hs.183817   ESTs   2.94   DU145, LnCap, LnCap       316507   AI381515   Hs.158381   ESTs   2.94   PRSC_con, PRSC_log, RPWE-2       302278   AF018080   Hs.173730   Mediterranean fever   2.93   EB, NCI-H69, DU145       311016   AW173166   Hs.243468   ESTs   2.93   NCI-H345, LnCap, LnCap       323864   AA340724   Hs.214028   ESTs   2.92   EB, Caco2, HT29       336632           CH22_FGENES.13-2   2.92   NCI-H69, NCI-H345, MB-MDA-231       328886           CH.07_hs gi|6588003   2.92   HT29, PC3, LnCap       301859   T61587       EST cluster (not in UniGene) with exon h   2.92   LnCap, EB, EB       323775   AA329856   Hs.143022   ESTs   2.92   PRSC_con, PRSC_log, RPWE-2       315426   AI391486   Hs.128171   ESTs   2.92   CALU6, EB, A549       322264   AF086242       EST cluster (not in UniGene)   2.92   Caco2, OVCA-R, DU145       315135   AA627561   Hs.192446   ESTs   2.91   EB, HT29, DU145       327982           CH.06_hs gi|5868216   2.91   LnCap, MS-MDA-453, NCI-H169       314530   AI052358   Hs.131741   ESTs   2.91   NCI-H460, NCI-H520, RPWE-2       315003   AA527650   Hs.156037   ESTs   2.9   PRSC_con, RPWE-2, MB-MDA-231       339032           CH22_DA59H18.GENSCAN.25-1   2.9   NCI-H69, PRSC_con, RPWE-2       308379   AI623950   Hs.2186   eukaryotic translation elongation factor   2.89   BT474, MB-MDA-231, HT29       312133   T87714   Hs.221665   ESTs   2.88   Caco2, MB-MDA-453, MCF7       307992   AI434166       EST singleton (not in UniGene) with exon   2.88   NCI-H520, MCF7, NCI-H23       308010   AI439190   Hs.181165   eukaryotic translation elongation factor   2.88   Caco2, NCI-H69, NCI-H345       320154   AA336019   Hs.119559   ESTs   2.88   MB-MDA-453, DU145, EB       331496   N34929   Hs.171984   ESTs   2.86   MB-MDA-453, PC3, MCF7       320016   H57622   Hs.194574   ESTs   2.86   PRSC_con, RPWE-2, PRSC_log       317923   AW450544   Hs.220751   ESTs   2.86   NCI-H345, PRSC_con, PRSC_log       301822   X17033   Hs.1142   integrin; alpha 2 (CD49B: alpha 2 subuni   2.86   PC3, BT474, CALU6       311759   AA705075   Hs.169536   Rhesus blood group-associated glycoprote   2.85   DU145, HT29, MB-MDA-231       315083   AI221325   Hs.210655   ESTs   2.84   PRSC_con, RPWE-2, NCI-H345       317759   AI908455   Hs.202460   ESTs; Weakly similar to hypothetical L1   2.83   HT29, MB-MDA-231, BT474       313980   AI633205   Hs.159914   ESTs   2.83   Caco2, MB-MDA-453, A549       310941   AI453402   Hs.173705   ESTs; Weakly similar to !!!! ALU CLASS C   2.83   NCI-H345, MCF7, Caco2       313593   AI911488   Hs.213724   ESTs   2.83   LnCap, Caco2, NCI-H460       314973   AW273128   Hs.254669   EST   2.82   BT474, LnCap, RPWE-2       310950   AI582758   Hs.170561   ESTs   2.82   EB, MB-MDA-453, LnCap       323626   AL039822   Hs.207604   ESTs   2.82   PC3, HT29, CALU6       325410           CH.12_hs gi|5866921   2.81   MB-MDA-453, PRSC_con, NCI-358       313911   AI565458   Hs.116385   ESTs   2.81   PRSC_con, EB, RPWE-2       334244           CH22_GENES.365_5   2.81   OVCA-R, PC3, MB-MDA-453       309333   AW025709       EST singleton (not in UniGene) with exon   2.81   NCI-H460, NCI-H23, NCI-358       328467           CH.07_hs gi|5868434   2.81   EB, OVCA-R, HT29       318563   AW250501       EST cluster (not in UniGene)   2.81   BT474, NCI-H23, MB-MDA-231       326412           CH.19_hs gi|5867362   2.81   BT474, PRSC_log, RPWE-2       303407   AA309616       EST cluster (not in UniGene) with exon h   2.8   CALU6, NCI-H345, DU145       328462           CH.07_hs gi|5868433   2.8   BT474, CALU6, MCF7       335157           CH22_FGENES.501_7   2.8   NCI-H69, NCI-H345, PRSC_log       313458   AA007259   Hs.255853   ESTs   2.79   OVCA-R, DU145, LnCap       310416   AI695047   Hs.202395   ESTs   2.79   DU145, MB-MDA-435s, PC3       317709   AI435973   Hs.128056   ESTs   2.79   NCI-H460, NCI-358, DU145       321415   AI377596   Hs.3337   transmembrane 4 superfamily member 1   2.79   A549, PC3, OVCA-R       313693   AW469180   Hs.170651   ESTs   2.79   OVCA-R, MCF7, EB       309438   AW102802   Hs.225787   ESTs; Moderately similar to hypothetical   2.79   PC3, OVCA-R, DU145       308961   AI870248       EST singleton (not in UniGene) with exon   2.78   BT474, MB-MDA-231, EB       329107           CH.X_hs gi|5868626   2.78   DU145, MCF7, MB-MDA-435s       313975   AW025024   Hs.65114   keratin 18   2.78   Caco2, EB, DU145       330901   AA157818   Hs.238380   Human endogenous retroviral pretease mRN   2.78   PC3, NCI-H520, BT474       311749   R06249   Hs.13911   ESTs   2.78   OVCA-R, MB-MDA-453, MCF7       329853           CH.14_p2 gi|6682295   2.78   BT474, BT474, HT29       322340   AF088076       EST cluster (not in UniGene)   2.77   NCI-H345, Caco2, LnCap       326806           CH.20_hs gi|6469835   2.77   NCI-H69, NCI-H345, MB-MDA-231       314661   AA436432       EST cluster (not in UniGene)   2.77   NCI-H460, MB-MDA-435s, CALU6       322135   AF075082       EST cluster (not in UniGene)   2.77   NCI-358, NCI-H460, Caco2       331849   AA417078   Hs.193767   ESTs   2.77   DU145, EB, CALU6       301056   AI797955   Hs.208076   ESTs; Weakly similar to D(4) DOPAMINE RE   2.76   NCI-H69, RPWE-2, PRSC_con       327739           CH.05_hs gi|5867942   2.76   EB, PC3, LnCap       308016   AI445116       EST singleton (not in UniGene) with exon   2.76   LnCap, HT29, MB-MDA-231       331549   N56866   Hs.237507   EST   2.76   MB-MDA-453, MCF7, OVCA-R       331851   AA418599   Hs.98303   caveolin 3   2.75   MB-MDA-231, NCI-H345, BT474       315023   AA533505   Hs.185844   ESTs   2.75   PRSC_con, OVCA-R, EB       335565           CH22_FGENES.579_1   2.75   OVCA-R, EB, A549       306137   AA916176       EST singleton (not in UniGene) with exon   2.74   EB, LnCap, DU145       332240   N54803       yv31d2.s1 Soares fetal liver spleen 1NFL   2.74   DU145, EB, CALU6                   3′ similar to contains L1.t3 L1 repetit       313246   N90762   Hs.159454   ESTs   2.74   NCI-H69, NCI-H345, PRSC_log       303642   AW299459       EST cluster (not in UniGene) with exon h   2.74   EB, A549, Caco2       325513           CH.12_hs gi|6017035   2.74   MB-MDA-231, NCI-H345, BT7474       337236           CH22_FGENES.639-2   2.74   MCF7, MB-MDA-453, NCI-H69       311555   AW407892   Hs.244807   ESTs   2.74   BT474, NCI-H345, NCI-H69       339266           CH22_BA354I12.GENSCAN.10-4   2.73   CALU6, DU145, OVCA-R       300127   AW028615   Hs.235224   ESTs; Weakly similar to KIAA0422 [ H. sapi     2.73   NCI-H345, RPWE-2, PRSC_log       311741   R00099   Hs.193642   ESTs   2.72   LnCap, PC3, OVCA-R       310915   AW449673   Hs.201893   ESTs   2.72   DU145, EB, MB-MDA-435s       324982   T31689   Hs.98518   ESTs   2.71   PRSC_con, PRSC_log, RPWE-2       305030   AA629988       EST singleton (not in UniGene) with exon   2.71   DU145, DU145, NCI-358       315396   AW296107   Hs.152686   ESTs   2.69   OVCA-R, Oaco2, EB       319098   AI908374       EST cluster (not in UniGene)   2.69   RPWE-2, LnCap, PC3       309119   AI927384   Hs.228499   EST; Moderately similar to PK-120 precur   2.69   LnCap, NCI-H23, NCI-358       312095   AW444937   Hs.233482   ESTs   2.68   Caco2, OVCA-R, HT29       324316   AI291330       EST cluster (not in UniGene)   2.68   NCI-H460, Caco2, PRSC_log       331367   AA425688   Hs.41641   ESTs; Weakly similar to CAGH4 [ H. sapiens     2.68   MB-MDA-435s, NCI-H520, NCI-H460       339116           CH22_DA59H18.GENSCAN.49-4   2.68   DU145, EB, CALU6       324297   AI565566   Hs.168587   ESTs   2.68   PRSC_con, OVCA-R, PRSC_log       318728   Z30201       EST cluster (not in UniGene)   2.68   LnCap, Caco2, PC3       304813   AA584540       EST singleton (not in UniGene) with exon   2.68   BT474, OVCA-R, RPWE-2       312393   N34376   Hs.191659   ESTs; Weakly similar to !!!! ALU CLASS E   2.68   NCI-H345, PRSC_con, EB       330671   AB002302   Hs.92236   KIAA0304 gene product   2.67   NCI-358, OVCA-R, Caco2       305406   AA723860       EST singleton (not in UniGene) with exon   2.66   OVCA-R, EB, MCF7       330957   H08778   Hs.133521   ESTs   2.66   EB, PC3, OVCA-R       300350   AI871129   Hs.172597   ESTs; Weakly similar to zinc finger prot   2.66   NCI-H23, NCI-H520, NCI-H460       322302   W76021       EST cluster (not in UniGene)   2.66   DU145, OVCA-R, PC3       321891   AW157424   Hs.165954   ESTs   2.66   EB, OVCA-R, Caco2       300124   AI217394   Hs.242447   ESTs   2.65   PRSC_con, A549, HT29       302747   AF062275       EST cluster (not in UniGene) with exon h   2.65   NCI-H23, BT474, MCF7       309741   AI802780   Hs.209002   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.65   PC3, EB, OVCA-R       310802   AI631546   Hs.159732   ESTs   2.65   PRSC_con, PRSC_log, NCI-H69       300694   AA063406       EST cluster (not in UniGene) with exon h   2.65   BT474, EB, MCF7       311395   R23313       EST cluster (not in UniGene)   2.64   EB, OVCA-R, DU145       336538           CH22_FGENES.840_2   2.64   DU145, NCI-H460, NCI-358       316473   AA829961       EST cluster (not in UniGene)   2.64   LnCap, OVCA-R, EB       328134           CH.06_hs gi|5868039   2.64   LnCap, EB, CALU6       329330           CH.X_hs gi|5868806   2.64   EB, CALU6, DU145       316664   AI042101       EST cluster (not in UniGene)   2.64   NCI-H345, MB-MDA-231, PRSC_log       328015           CH.06_hs gi|5902482   2.63   BT474, HT29, MB-MDA-231       308991   AI879831       EST singleton (not in UniGene) with exon   2.63   BT474, EB, NCI-H23       323899   AL042966       EST cluster (not in UniGene)   2.62   DU145, A549, CALU6       321708   AA476817       EST cluster (not in UniGene)   2.62   EB, A549, CALU6       301752   T75247       EST cluster (not in UniGene) with exon h   2.62   HT29, BT474, NCI-H345       309351   AW057547       EST singleton (not in UniGene) with exon   2.62   NCI-H23, PRSC_con, LnCap       314412   AI864270   Hs.155654   ESTs   2.62   CALU6, MB-MDA-231, BT474       309441   AW103055   Hs.244230   EST   2.62   BT474, MB-MDA-231, MB-MDA-453       335993           CH22_FGENES.656_6   2.61   NCI-H460, NCI-358, NCI-H520       318196   AI056776   Hs.133397   ESTs   2.6   EB, CALU6, HT29       322880   AA310521   Hs.50848   ESTs; Weakly similar to KIAA0862 protein   2.6   DU145, A549, PC3       300558   AI540051   Hs.122638   ESTs   2.6   OVCA-R, NCI-H69, MCF7       318594   AA918320   Hs.224581   ESTs   2.6   PC3, MB-MDA-453, DU145       308554   AI698132   Hs.201923   EST   2.6   LnCap, EB, NCI-H345       335108           CH22_FGENES.494_14   2.6   NCI-H69, NCI-H345, MB-MDA-231       312483   AI417526   Hs.184636   ESTs   2.59   PC3, DU145, OVCA-R       311981   AW452773   Hs.257612   EST   2.59   NCI-H460, MB-MDA-453, NCI-H23       319359   F13458       EST cluster (not in UniGene)   2.59   LnCap, NCI-H460, MB-MDA-231       300230   AI377746   Hs.158846   ESTs   2.59   HT29, NCI-358, NCI-H345       316504   AW135854   Hs.132458   ESTs   2.59   DU145, EB, CALU6       322337   AA249804       EST cluster (not in UniGene)   2.59   NCI-H69, NCI-H345, NCl-H345       301775   AW247670       EST cluster (not in UniGene) with exon h   2.59   NCI-H345, RPWE-2, PRSC_log       301089   AA666396   Hs.220727   ESTs   2.58   PRSC_log, PRSC_con, RPWE-2       331213   T88698   Hs.163862   ESTs   2.58   DU145, EB, OVCA-R       321121   W23285       EST cluster (not in UniGene)   2.58   NCI-H69, MB-MDA-435s, PC3       316634   AW241910   Hs.122254   ESTs   2.58   MCF7, HT29, BT474       322141   AF075092       EST cluster (not in UniGene)   2.58   PC3, OVCA-R, HT29       312108   T82331   Hs.127453   ESTs   2.58   A549, CALU6, Caco2       339071           CH22_DA59H18.GENSCAN.34-1   2.58   CALU6, DU145, EB       311666   AW389509   Hs.223747   ESTs   2.57   OVCA-R, MB-MDA-231, BT474       318662   AI285898   Hs.115367   ESTs   2.57   OVCA-R, DU145, EB       317010   AA863395       EST cluster (not in UniGene)   2.57   NCI-H520, PRSC_con, NCI-358       324710   AI742028   Hs.120884   ESTs; Weakly similar to RAS-RELATED PROT   2.57   LnCap, DU145, MB-MDA-453       327888           CH.06_hs gi|5868149   2.56   NCI-H345, MB-MDA-435s, RPWE-2       336149           CH22_FGENES.706.5   2.56   NCI-H69, PC3, A549       312816   H74319   Hs.188620   ESTs   2.56   EB, Caco2, NCI-H460       327999           CH.06_hs gi|5867994   2.56   NCI-358, NCI-H520, NCI-H23       316761   AI911173   Hs.213722   ESTs   2.55   NCI-H345, NCI-H460, MB-MDA-231       336958           CH22_FGENES.367-1   2.55   HT29, CALU6, CALU6       325043   W27919   Hs.32944   inositol polyphosphate-4-phosphatase; ty   2.55   NCI-H460, NCI-H23, HT29       315417   AW452360   Hs.186770   ESTs   2.55   NCI-H345, NCI-H69, PRSC_con       331603   N78656   Hs.161535   EST   2.55   NCI-H345, PRSC_con, PRSC_log       309403   AW082954       EST singleton (not in UniGene) with exon   2.55   BT474, MB-MDA-231, MCF7       337289           CH22_FGENES.672-8   2.54   BT474, HT29, MB-MDA-231       314242   AI570943   Hs.246280   ESTs   2.54   Caco2, MB-MDA-435s, MB-MDA-453       328053           CH.06_hs gi|5902482   2.54   MB-MDA-231, DU145, MB-MDA-453       307215   AI193189       EST singleton (not in UniGene) with exon   2.53   HT29, CALU6, MB-MDA-231       327566           CH.03_hs gi|5867811   2.53   NCI-H69, NCI-H520, NCI-H345       326338           CH.17_hs gi|6056311   2.53   PC3, A549, DU145       318115   AI384027   Hs.159130   ESTs; Moderately similar to !!!! ALU SUB   2.53   DU145, EB, PC3       307437   AI245683       EST singleton (not in UniGene) with exon   2.52   NCI-H23, NCI-H520, NCI-358       322059   AA412371   Hs.121344   ESTs   2.52   EB, DU145, OVCA-R       322505   AF147315       EST cluster (not in UniGene)   2.52   PRSC_con, RPWE-2, NCI-H69       314032   AW081897   Hs.193211   ESTs   2.52   NCI-H345, LnCap, DU145       336125           CH22_FGENES.701_12   2.51   NCI-H69, LnCap, DU145       312765   AI692908   Hs.181873   ESTs   2.51   NCI-H23, NCI-358, NCI-H520       335523           CH22_FGENES.572_3   2.51   HT29, BT474, OVCA-R       327585           CH.03_hs gi|5867825   2.51   HT29, NCI-H460, MB-MDA-453       323183   AW393850       EST cluster (not in UniGene)   2.51   MB-MDA-231, LnCap, RPWE-2       314418   AI478722   Hs.232275   ESTs; Moderately similar to !!!! ALU SUB   2.51   EB, DU145, DU145       313361   AI359782   Hs.137312   ESTs   2.5   CALU6, HT29, DU145       305632   AA805276       EST singleton (not in UniGene) with exon   2.5   MB-MDA-453, NCI-H460, NCI-H23       331689   W90131   Hs.184675   ESTs   2.5   NCI-H69, EB, A549       323438   AI540243   Hs.113817   ESTs   2.5   NCI-H345, PRSC_con, MB-MDA-231       315742   AI821724   Hs.143198     H sapiens  PAC clone DJ0872F07 from 7q31   2.5   MCF7, MB-MDA-453, MB-MDA-435s       305971   AA886874       EST singleton (not in UniGene) with exon   2.5   NCI-358, NCI-H23, NCI-H520       336633           CH22_FGENES.13-3   2.5   NCI-H69, NCI-H345, PRSC_log       304746   AA577793       EST singleton (not in UniGene) with exon   2.49   NCI-H69, BT474, MB-MDA-231       327925           CH.06_hs gi|5868172   2.49   NCI-358, NCI-358, NCI-H460       336055           CH22_FGENES.683_4   2.49   EB, HT29, MB-MDA-231       328888           CH.07_hs gi|6588003   2.48   MB-MDA-435s, MB-MDA-453, PRSC_log       311244   AW016694   Hs.197689   ESTs   2.48   NCI-H345, MCF7, PC3       327155           CH.01_hs gi|5867549   2.48   NCI-H69, MB-MDA-231, NCI-H345       334907           CH22_FGENES.453_2   2.48   DU145, NCI-H345, MB-MDA-231       314887   AA910236   Hs.139469   ESTs   2.48   DU145, A549, A549       339435           CH22_DJ579N16.GENSCAN.18-10   2.48   NCI-H69, MCF7, BT474       334172           CH22_FGENES.349_5   2.48   NCI-H69, NCI-H345, PRSC_log       320767   AA299525       EST cluster (not in UniGene)   2.48   NCI-358, NCI-H23, NCI-H460       338772           CH22_FGENES.156-1   2.47   NCI-358, NCI-358, NCI-H23       326957           CH.21_hs gi|6469836   2.47   BT474, RPWE-2, PRSC_con       308505   AI686615   Hs.200778   EST; Weakly similar to SALIVARY PROLINE-   2.47   MCF7, MB-MDA-453, MB-MDA-435s       321325   AB033100       EST cluster (not in UniGene)   2.47   EB, CALU6, A549       313149   AW291092   Hs.201058   ESTs   2.47   NCI-H345, PRSC_con, RPWE-2       338325           CH22_EM:AC005500.GENSCAN.307-7   2.46   BT474, LnCap, EB       307877   AI368880       EST singleton (not in UniGene) with exon   2.46   NCI-H23, PRSC_log, NCI-H520       311525   AI799444   Hs.247095   ESTs; Moderately similar to !!!! ALU SUB   2.46   PRSC_con, PRSC_log, NCI-H345       337023           CH22_FGENES.433-12   2.46   OVCA-R, CALU6, PRSC_con       300916   AI361798   Hs.164675   ESTs   2.45   LnCap, DU145, CALU6       302919   AL137382       EST cluster (not in UniGene) with exon h   2.45   LnCap, MB-MDA-231, CALU6       320303   AL079289   Hs.137154     H sapiens  mRNA full length insert cDNA c   2.45   BT474, MB-MDA-231, MB-MDA-453       318359   AI097439   Hs.135548   ESTs   2.45   NCI-H460, MB-MDA-453, NCI-H345       314384   AA535840   Hs.162203   ESTs; Weakly similar to altematively sp   2.45   OVCA-R, PC3, EB       326763           CH.20_hs gi|6598307   2.45   NCI-H69, NCI-H345, RPWE-2       319900   AW408392       EST cluster (not in UniGene)   2.45   Caco2, NCI-H460, NCI-H23       314451   AA586368   Hs.190232   ESTs   2.45   PRSC_con, NCI-H345, MB-MDA-231       300641   AW237699   Hs.118346   ESTs   2.44   NCI-H345, PRSC_log, PRSC_con       324368   AW299374       EST cluster (not in UniGene)   2.44   PC3, DU145, OVCA-R       336510           CH22_FGENES.834_5   2.44   NCI-H69, RPWE-2, PRSC_con       326876           CH.20_hs gi|6682507   2.44   NCI-H23, NCI-H460, NCI-H520       307753   AI340509   Hs.182426   ribosomal protein S2   2.44   NCI-H23, NCI-H460, Caco2       317071   M78728   Hs.132694   ESTs   2.44   NCI-H345, NCI-H69, RPWE-2       313877   AA767869   Hs.250113   ESTs; Moderately similar to thyroid horm   2.44   DU145, LnCap, CALU6                   component TRAP150 [ H. sapiens ]       315974   AW029203   Hs.191952   ESTs   2.43   EB, DU145, OVCA-R       322970   AI885052   Hs.142287   ESTs; Weakly similar to !!!! ALU CLASS F   2.43   NCI-H345, RPWE-2, EB       317733   AI028257   Hs.132317   ESTs   2.43   CALU6, RPWE-2, OVCA-R       313599   AA748749   Hs.136742   ESTs   2.42   NCI-H460, NCI-358, NCI-H520       323014   AA305198       EST cluster (not in UniGene)   2.42   PRSC_con, NCI-H460, RPWE-2       324980   AA969121   Hs.254296   ESTs   2.41   MCF7, OVCA-R, PC3       301326   AA883831   Hs.252924   ESTs   2.41   PRSC_con, PRSC_log, RPWE-2       308695   AI763350       EST singleton (not in UniGene) with exon   2.41   RPWE-2, NCI-H69, NCI-H345       330166           CH.02_p2 gi|6648220   2.41   CALU6, DU145, A549       317552   AW451400   Hs.127019   ESTs   2.41   NCI-358, NCI-358, NCI-H23       320572   AI929508   Hs.159590   lymphocyte antigen 6 complex; locus H   2.41   CALU6, HT29, A549       315618   AI287341   Hs.154029   ESTs; Weakly similar to TRANSCRIPTION FA   2.41   OVCA-R, Caco2, MB-MDA-231       331610   N91109   Hs.54681   ESTs   2.41   NCI-H23, NCI-H520, NCI-358       311731   AW393528   Hs.246875   ESTs   2.41   NCI-H69, NCI-H345, PRSC_con       318571   Z43383   Hs.8053   ESTs   2.4   NCI-358, NCI-H23, NCI-H520       334958           CH22_FGENES.465_27   2.4   DU145, PRSC_con, RPWE-2       323570   AL038623   Hs.208752   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.4   OVCA-R, EB, BT474       301685   W67730       EST cluster (not in UniGene) with exon h   2.4   MB-MDA-231, NCI-H345, EB       303849   AW163324       EST cluster (not in UniGene) with exon h   2.4   RPWE-2, PRSC_log, NCI-H345       325702           CH.14_hs gi|5867028   2.4   NCI-H23, NCI-H460, NCI-H520       313074   N48261   Hs.127171   ESTs   2.4   MB-MDA-231, RPWE-2, PRSC_log       308994   AI880051       EST singleton (not in UniGene) with exon   2.4   RPWE-2, EB, PRSC_con       330338           CH.08_p2 gi|5457162   2.4   DU145, EB, LnCap       327274           CH.01_hs gi|5867470   2.4   OVCA-R, DU145, MB-MDA-231       325953           CH.16_hs gi|5867140   2.4   MB-MDA-453, MB-MDA-435s, MCF7       333281           CH22_FGENES.128_7   2.4   NCI-H23, HT29, DU145       314778   AW079559   Hs.152258   ESTs   2.39   EB, CALU6, Caco2       317005   AI800251   Hs.197773   ESTs   2.38   MB-MDA-231, BT474, HT29       334257           CH22_FGENES.367_5   2.38   HT29, NCI-358, MB-MDA-231       324783   AA640770       EST cluster (not in UniGene)   2.38   EB, OVCA-R, MB-MDA-453       300949   AA534325   Hs.162183   ESTs   2.38   NCI-H69, NCI-H345, PRSC_log       314957   AW029274   Hs.208368   ESTs; Moderately similar to !!!! ALU SUB   2.38   LnCap, DU145, DU145       324350   AW292501   Hs.157174   ESTs; Weakly similar to similar to SH3-b   2.38   HT29, NCI-H23, NCI-H23       338235           CH22_EM:AC005500.GENSCAN.260-16   2.38   NCI-H69, NCI-H460, NCI-H23       300937   AW297302   Hs.255631   ESTs   2.38   PRSC_log, PRSC_con, PRSC_con       317439   AW451327   Hs.170623   ESTs   2.38   A549, DU145, EB       324745   AI742120   Hs.116506   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.38   NCI-358, NCI-H460, BT474       338306           CH22_EM:AC005500.GENSCAN.302-2   2.38   NCI-H69, PRSC_con, PRSC_log       318765   Z42071   Hs.23961   ESTs   2.38   LnCap, NCI-H23, NCI-H520       310254   AI239811   Hs.157491   ESTs   2.37   OVCA-R, DU145, EB       305116   AA649244       EST singleton (not in UniGene) with exon   2.37   CALU6, MB-MDA-435s, MB-MDA-453       324016   AL045285   Hs.245849   ESTs; Moderately similar to !!!! ALU SUB   2.37   EB, DU145, OVCA-R       322774   AA131111       EST cluster (not in UniGene)   2.37   OVCA-R, EB, A549       335745           CH22_FGENES.601_16   2.37   PRSC_log, PRSC_con, NCI-H69       300972   AI979100   Hs.211518   ESTs   2.37   NCI-H69, NCI-H345, PRSC_log       338809           CH22_EMAC005500.GENSCAN.531-10   2.37   NCI-H23, NCI-H69, NCI-H520       316983   AI480204   Hs.177131   ESTs   2.37   NCI-H345, PRSC_con, PRSC_log       321308   AI247480   Hs.117029   ESTs   2.37   BT474, NCI-H69, HT29       323578   AA299492   Hs.168166   ESTs   2.37   LnCap, EB, MB-MDA-453       335747           CH22_FGENES.601_20   2.36   NCI-H69, LnCap, PRSC_con       322362   AF039697       EST cluster (not in UniGene)   2.36   DU145, PRSC_con, NCI-H345       314430   N76302   Hs.78110   ESTs; Weakly similar to F17A9.2 [ C. elega     2.36   DU145, MB-MDA-453, CALU6       304831   AA586422       EST singleton (not in UniGene) with exon   2.36   NCI-H23, NCI-H460, CALU6       337432           CH22_FGENES.765-1   2.36   MB-MDA-231, BT474, HT29       305984   AA887654       EST singleton (not in UniGene) with exon   2.36   DU145, HT29, CALU6       313486   AW134523   Hs.247186   ESTs   2.36   DU145, A549, CALU6       309028   AI889109   Hs.212032   EST   2.36   NCI-358, NCI-H520, NCI-H23       318292   AI679966   Hs.150603   ESTs   2.35   NCI-H460, Caco2, NCI-H23       334198           CH22_FGENES.354_4   2.35   NCI-H69, PRSC_log, PRSC_con       314458   AI217440   Hs.143873   ESTs   2.35   Caco2, A549, PC3       333346           CH22_FGENES.139_15   2.35   CALU6, DU145, LnCap       325408           CH.12_hs gi|5866921   2.35   NCI-H460, NCI-H520, NCI-H23       313758   AA076743   Hs.129770   ESTs   2.35   NCI-H23, MB-MDA-435s, NCI-H345       309825   AW293701       EST singleton (not in UniGene) with exon   2.35   NCI-H460, NCI-H23, NCI-H520       303536   R55497   Hs.183941   ESTs; Moderately similar to H beta 58 ho   2.35   DU145, CALU6, NCI-H520       331534   N51583   Hs.133756   EST   2.35   NCI-H23, NCI-H520, NCI-358       325164   T16981   Hs.21963   ESTs   2.34   NCI-H345, PRSC_log, NCI-H460       327710           CH.04_hs gi|5867860   2.34   BT474, MB-MDA-231, NCI-H345       306351   AA961356       EST singleton (not in UniGene) with exon   2.34   BT474, MB-MDA-231, MB-MDA-435s       304968   AA614308       EST singleton (not in UniGene) with exon   2.34   CALU6, HT29, MB-MDA-453       334015           CH22_FGENES.313_7   2.34   HT29, MB-MDA-231, BT474       318315   AI091370   Hs.134852   ESTs   2.33   CALU6, NCI-H520, DU145       306809   AI057134       EST singleton (not in UniGene) with exon   2.33   PC3, DU145, EB       337697           CH22_EM:AC000097.GENSCAN.86-1   2.33   RPWE-2, PRSC_log, NCI-H345       329630           CH.11_p2 gi|6729060   2.33   NCI-H520, NCI-H23, NCI-H460       326577           CH.19_hs gi|5867317   2.33   NCI-H460, NCI-358, NCI-H23       333428           CH22_FGENES.149_1   2.33   NCI-H345, PRSC_con, RPWE-2       301080   AI479391   Hs.155405   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.33   OVCA-R, MCF7, MCF7       324829   AA714311       EST cluster (not in UniGene)   2.33   NCI-H460, NCI-358, NCI-H23       302776   AJ133798       EST cluster (not in UniGene) with exon h   2.32   NCI-H23, NCI-H460, NCI-H520       325801           CH.14_hs gi|6552451   2.32   PRSC_log, MCF7, NCI-H23       332122   AA609698   Hs.112389   ESTs   2.32   DU145, HT29, PC3       314167   AA243633   Hs.208983   ESTs   2.32   DU145, MCF7, PC3       324023   AA669615   Hs.214226   ESTs   2.31   DU145, NCI-H345, EB       320503   NM_00589       EST cluster (not in UniGene)   2.31   A549, OVCA-R, PC3       312217   T98289       EST cluster (not in UniGene)   2.31   NCI-H23, Caco2, NCI-H69       321304   AA078293       EST cluster (not in UniGene)   2.31   DU145, OVCA-R, EB       323517   AA527359   Hs.154366   ESTs   2.31   NCI-H345, DU145, EB       336455           CH22_FGENES.829_13   2.31   NCI-H345, PRSC_con, RPWE-2       313352   AW292127   Hs.144758   ESTs   2.31   MCF7, DU145, OVCA-R       331457   H93135   Hs.41840   ESTs   2.31   Caco2, NCI-H460, NCI-H23       333054           CH22_FGENES.73_8   2.31   NCI-H69, NCI-358, NCI-H23       308598   AI719237       EST singleton (not in UniGene) with exon   2.31   OVCA-R, CALU6, Caco2       327059           CH.21_hs gi|6531965   2.3   NCI-H460, LnCap, LnCap       334120           CH22_FGENES.333_1   2.3   NCI-H69, RPWE-2, MB-MDA-435s       324154   AI457449   Hs.192817   ESTs   2.3   NCI-H460, MB-MDA-453, NCI-358       326509           CH.19_hs gi|6682496   2.3   NCI-H345, CALU6, OVCA-R       316855   AW291384   Hs.254974   ESTs   2.3   NCI-H345, NCI-H460, BT474       337918           CH22_EM:AC005500.GENSCAN.66-4   2.3   RPWE-2, NCI-H345, PRSC_log       317471   AI825351   Hs.144084   ESTs   2.29   HT29, OVCA-R, DU145       331023   N32599   Hs.5856   ESTs   2.29   OVCA-R, LnCap, A549       332231   N48008   Hs.102629   EST   2.29   CALU6, DU145, EB       309912   AW339671       EST singleton (not in UniGene) with exon   2.29   MB-MDA-435s, PRSC_con, NCI-358       316427   AI241019   Hs.145644   ESTs   2.29   Caco2, HT29, EB       313329   AW293704   Hs.122658   ESTs   2.29   OVCA-R, DU145, Caco2       335019           CH22_FGENES.474_7   2.29   HT29, CALU6, MB-MDA-231       324394   F20654   Hs.152128   ESTs; Moderately similar to !!!! ALU SUB   2.29   NCI-H345, MB-MDA-231, RPWE-2       339357           CH22_BA354|12.GENSCAN.31-2   2.29   NCI-H69, OVCA-R, BT474       322128   AI346033       EST cluster (not in UniGene)   2.28   NCI-H23, NCI-H520, NCI-H460       301310   AI239457   Hs.130794   ESTs   2.28   OVCA-R, DU145, MB-MDA-231       300623   AI929130   Hs.118261   ESTs; Moderately similar to finger prote   2.28   BT474, RPWE-2, PRSC_con       323409   AL135534       EST cluster (not in UniGene)   2.27   NCI-H345, NCI-358, Caco2       308406   AI634885       EST singleton (not in UniGene) with exon   2.27   OVCA-R, EB, HT29       322518   AI133446       EST cluster (not in UniGene)   2.27   DU145, MB-MDA-435s, OVCA-R       338381           CH22_EM:AC005500.GENSCAN.330-10   2.27   NCI-H69, PRSC_con, PRSC_log       316003   AA704584   Hs.119993   ESTs   2.27   NCI-358, NCI-H520, NCI-H23       307090   AI161024       EST singleton (not in UniGene) with exon   2.27   NCI-H345, DU145, RPWE-2       300356   AA758411   Hs.121335   ESTs   2.27   LnCap, NCI-H460, Caco2       331887   AA431328   Hs.98660   ESTs   2.27   NCI-358, NCI-H520, CALU6       330951   H02566   Hs.191268     H sapiens  mRNA; cDNA DKFZp434N174 (from   2.27   OVCA-R, BT474, BT474       305547   AA773111       EST singleton (not in UniGene) with exon   2.27   LnCap, DU145, BT474       312457   AA776743   Hs.191589   ESTs   2.26   NCI-H345, RPWE-2, PRSC_con       333929           CH22_FGENES.300_2   2.26   HT29, CALU6, EB       319845   AA649011   Hs.187902   ESTs   2.26   LnCap, DU145, MCF7       306739   AI028393       EST singleton (not in UniGene) with exon   2.26   MB-MDA-435s, NCI-358, CALU6       306919   AI096832       EST singleton (not in UniGene) with exon   2.26   HT29, BT474, PC3       333312           CH22_FGENES.138_4   2.26   OVCA-R, DU145, PC3       334955           CH22_FGENES.465_24   2.25   RPWE-2, PRSC_con, NCI-H345       312295   AA578233   Hs.173863   ESTs   2.25   OVCA-R, DU145, NCI-H345       307643   AI302124       EST singleton (not in UniGene) with exon   2.25   CALU6, CALU6, OVCA-R       324252   AA421989       EST cluster (not in UniGene)   2.25   OVCA-R, EB, A549       309767   AW271805       EST singleton (not in UniGene) with exon   2.25   DU145, NCI-H460, CALU6       311492   AW410240   Hs.4437   ribosomal protein L28   2.25   NCI-H69, NCI-H460, NCI-H520       312260   H05392   Hs.230597   EST   2.25   Caco2, EB, DU145       327125           CH.21_hs gi|6531971   2.25   HT29, NCI-358, BT474       316919   AA845382   Hs.204520   ESTs   2.24   NCI-H23, NCI-H345, NCI-H520       316361   AI433833   Hs.164159   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.24   DU145, EB, PC3       315772   AW515373   Hs.158893   ESTs   2.24   OVCA-R, EB, LnCap       320236   H03688       EST cluster (not in UniGene)   2.24   NCI-358, DU145, NCI-H23       315444   AW138821   Hs.221737   ESTs   2.24   NCI-358, CALU6, PRSC_con       333903           CH22_FGENES.294_1   2.24   MB-MDA-231, BT474, A549       335234           CH22_FGENES.515_3   2.24   NCI-H69, PRSC_con, PRSC_log       333727           CH22_FGENES.256_1   2.23   MB-MDA-231, NCI-H69, BT474       332002   AA482009   Hs.105104   ESTs   2.23   EB, NCI-H520, HT29       329611           CH.10_p2 gi|3962478   2.23   BT474, HT29, MB-MDA-231       310559   AI783594   Hs.155718   ESTs   2.22   BT474, MCF7, MB-MDA-231       327315           CH.01_hs gi|5867508   2.22   NCI-H69, EB, EB       323170   U83527       EST cluster (not in UniGene)   2.22   EB, DU145, LnCap       331522   N49309   Hs.117012   ESTs   2.22   A549, LnCap, DU145       313261   AA730472   Hs.142805   ESTs   2.22   OVCA-R, PC3, LnCap       312740   R97191   Hs.134106   ESTs   2.22   BT474, MCF7, OVCA-R       325055   Z44631   Hs.21658   ESTs   2.22   MB-MDA-453, DU145, CALU6       337895           CH22_EM:AC005500.GENSCAN.56-2   2.22   NCI-H345, PRSC_log, PRSC_con       307140   AI185762       EST singleton (not in UniGene) with exon   2.22   NCI-H520, NCI-H460, EB       321643   W76005   Hs.32094   ESTs   2.21   EB, NCI-H345, PRSC_con       302683   X85153       EST cluster (not in UniGene) with exon h   2.21   BT474, MB-MDA-231, MCF7       322644   AA340904       EST cluster (not in UniGene)   2.21   NCI-H460, NCI-H23, NCI-H520       330415   D83777   Hs.75137   KIAA0193 gene product   2.21   CALU6, A549, Caco2       302334   AF120491       EST cluster (not in UniGene) with exon h   2.21   NCI-H69, NCI-H345, PC3       326710           CH.20_hs gi|5867593   2.21   NCI-H520, NCI-358, NCI-H23       323561   AA825426   Hs.238832   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.21   NCI-H345, DU145, NCI-H69       337706           CH22_EM:AC000097.GENSCAN.87-11   2.21   MB-MDA-435s, NCI-358, NCI-H520       339309           CH22_BA354I12.GENSCAN.22-7   2.21   BT474, HT29, PC3       330436   HG2724-H       Oncogene Tls/Chop, Fusion Activated   2.21   PRSC_con, NCI-H69, Caco2       312360   AI922972   Hs.196073   ESTs   2.21   OVCA-R, MB-MDA-435s, DU145       301855   AF053356       multiple UniGene matches   2.2   NCI-H69, HT29, NCI-H23       331192   T55182   Hs.152571   ESTs; Highly similar to IGF-II mRNA-bind   2.2   OVCA-R, PC3, CALU6       315872   AW051819   Hs.204516   ESTs   2.2   LnCap, OVCA-R, EB       337904           CH22_EM:AC005500.GENSCAN.56-17   2.2   OVCA-R, LnCap, EB       308258   AI565612       EST singleton (not in UniGene) with exon   2.2   DU145, MB-MDA-231, CALU6       320965   H18166       EST cluster (not in UniGene)   2.2   DU145, EB, LnCap       333910           CH22_FGENES.295_3   2.2   DU145, MB-MDA-231, EB       300707   AA080921       EST cluster (not in UniGene) with exon h   2.2   BT474, MCF7, HT29       336011           CH22_FGENES.668_9   2.19   NCI-H460, BT474, NCI-H345       325712           CH.14_hs gi|6682473   2.19   NCI-H460, NCI-H23, NCI-358       322738   AF201832       EST cluster (not in UniGene)   2.19   PC3, RPWE-2, PRSC_con       335339           CH22_FGENES.535_16   2.19   HT29, PRSC_log, MCF7       320733   AA738436   Hs.134407   ESTs   2.19   DU145, EB, Caco2       319412   AA679426   Hs.187505   ESTs   2.19   NCI-H345, PRSC_log, PRSC_con       337132           CH22_FGENES.526-3   2.19   NCI-H69, NCI-H345, PRSC_con       301544   AI951651   Hs.224290   ESTs   2.19   PRSC_con, MB-MDA-231, NCI-H23       325285           CH.11_hs gi|5866903   2.18   PRSC_con, PRSC_log, MB-MDA-231       338280           CH22_EM:AC005500.GENSCAN.290-11   2.18   PC3, NCI-358, HT29       311421   AI701635   Hs.207077   ESTs   2.18   RPWE-2, NCI-H345, NCI-358       330638   X89576   Hs.159581   matrix metalloproteinase 17 (membrane-in   2.18   HT29, MB-MDA-435s, MB-MDA-453       326603           CH.20_hs gi|6056312   2.18   CALU6, DU145, HT29       319055   AA412305       EST cluster (not in UniGene)   2.18   A549, OVCA-R, MB-MDA-435s       335451           CH22_FGENES.562_9   2.18   DU145, LnCap, CALU6       317989   AI203009   Hs.130664   ESTs   2.18   NCI-H345, NCI-H69, NCI-H520       322024   AA334384       EST cluster (not in UniGene)   2.18   Caco2, PC3, NCI-H520       300734   AW205197   Hs.240951   ESTs   2.18   NCI-358, A549, EB       304022   T02990       EST singleton (not in UniGene) with exon   2.18   NCI-H23, NCI-358, NCI-H460       330082           CH.19_p2 gi|6015314   2.18   NCI-H23, Caco2, Caco2       312516   AA363245   Hs.189831   ESTs   2.18   BT474, HT29, MB-MDA-231       333932           CH22_FGENES.300_5   2.17   PC3, Caco2, EB       308115   AI479071       EST singleton (not in UniGene) with exon   2.17   BT474, OVCA-R, OVCA-R       320184   U91510   Hs.123036   CD39-like 1   2.17   NCI-H520, NCI-358, NCI-H23       324432   AA464510       EST cluster (not in UniGene)   2.17   CALU6, RPWE-2, HT29       320882   AI832098       EST cluster (not in UniGene)   2.17   OVCA-R, PC3, BT474       312251   H03952       EST cluster (not in UniGene)   2.17   NCI-H460, NCI-H23, NCI-358       315049   AW340486   Hs.121210   ESTs   2.17   NCI-H520, NCI-358, NCI-H23       305018   AA627127       EST singleton (not in UniGene) with exon   2.17   MB-MDA-231, MB-MDA-453, EB       303807   AI792785   Hs.130434   ESTs   2.16   NCI-H345, PRSC_con, PRSC_log       317792   AI653389   Hs.196121   ESTs   2.16   NCI-H345, PRSC_con, LnCap       321668   AA872730   Hs.125229   ESTs   2.16   OVCA-R, PC3, MCF7       328863           CH.07_hs gi|6381929   2.16   PRSC_con, NCI-H345, NCI-H460       319373   R00371       EST cluster (not in UniGene)   2.16   PRSC_con, RPWE-2, NCI-H345       320069   T86541   Hs.189732   ESTs   2.16   NCI-H23, NCI-358, NCI-H345       320235   AF064090   Hs.129708   tumor necrosis factor (ligand) superfami   2.16   NCI-H23, NCI-8460, NCI-H520       338880           CH22_DJ32I10.GENSCAN.6-2   2.16   BT474, MCF7, OVCA-R       318314   AI091349   Hs.161133   ESTs   2.16   NCI-H23, NCI-H520, NCI-H460       332696   D86973   Hs.75354   GCN1 (general control of amino-acid synt   2.16   A549, PC3, DU145       331352   AA406133   Hs.7482   KIAA0682 gene product   2.16   PC3, EB, MB-MDA-231       339019           CH22_DA59H18.GENSCAN.21-15   2.15   LnCap, EB, OVCA-R       306975   AI127042       EST singleton (not in UniGene) with exon   2.15   MB-MDA-435s, NCI-H520, NCI-358       318069   AI024557   Hs.131540   ESTs   2.15   Caco2, Caco2, BT474       312997   AW205686   Hs.135130   ESTs   2.15   NCI-H460, NCI-H23, NCI-358       331372   AA433935   Hs.55044   DKFZP586H2123 protein   2.15   PRSC_con, HT29, CALU6       335049           CH22_FGENES.481_5   2.15   NCI-H69, NCI-H345, PRSC_log       324280   AA429772   Hs.191610   ESTs   2.15   MB-MDA-453, MB-MDA-435s, MCF7       330363           CH.X_p2 gi|3126882   2.15   NCI-H23, NCI-H460, NCI-358       322896   AW470296   Hs.144830   ESTs   2.15   HT29, CALU6, EB       321981   AA948204   Hs.127361   ESTs   2.15   MB-MDA-231, DU145, HT29       333294           CH22_FGENES.130_6   2.14   EB, DU145, MB-MDA-453       330170           CH.02_p2 gi|6648220   2.14   HT29, MB-MDA-453, PC3       312973   AI123346   Hs.135241   ESTs   2.14   LnCap, DU145, EB       311104   AI627352   Hs.201449   ESTs   2.14   NCI-H520, NCI-H23, LnCap       325086   T10019   Hs.4194   ESTs   2.14   NCI-H460, NCI-H23, NCI-358       317182   AW183524   Hs.192298   ESTs   2.14   HT29, BT474, MB-MDA-435s       323644   AA310711   Hs.124340   ESTs   2.14   RPWE-2, PRSC_con, PRSC_log       308092   AI474896       EST singleton (not in UniGene) with exon   2.14   BT474, MCF7, MB-MDA-231       322265   AF086244       EST cluster (not in UniGene)   2.14   NCI-H345, RPWE-2, PRSC_con       303521   AA746272       EST cluster (not in UniGene) with exon h   2.14   DU145, MB-MDA-453, EB       312102   AW439340   Hs.189720   ESTs   2.14   NCI-H23, NCI-H460, MB-MDA-435s       316559   AI249468   Hs.228251   EST   2.14   NCI-H460, NCI-358, NCI-H23       338486           CH22_EM:AC005500.GENSCAN.382-8   2.14   NCI-H520, NCI-H23, NCI-H69       301302   AI825444   Hs.210956   ESTs   2.14   BT474, HT29, MB-MDA-231       310591   AI650372   Hs.195979   ESTs   2.14   CALU6, CALU6, Caco2       316231   AA732301       EST cluster (not in UniGene)   2.14   NCI-H23, NCI-H520, NCI-358       326559           CH.19_hs gi|5867310   2.14   DU145, NCI-H460, NCI-H23       324062   AA525291   Hs.204099   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.13   OVCA-R, DU145, EB       323844   AI811303   Hs.143490   ESTs   2.13   MB-MDA-453, MCF7, MB-MDA-435s       333895           CH22_FGENES.293_2   2.13   CALU6, LnCap, DU145       308264   AI567114   Hs.171454   EST   2.13   DU145, CALU6, MB-MDA-453       306081   AA908472       EST singleton (not in UniGene) with exon   2.13   HT29, 6T474, MB-MDA-231       333101           CH22_FGENES.79_6   2.13   NCI-H345, NCI-H69, PRSC_log       328544           CH.07_hs gi|5868486   2.13   NCI-H23, NCI-H69, PRSC_log       333355           CH22_.FGENES.141_6   2.13   DU145, EB, CALU6       323397   AI524519   Hs.239699   ESTs   2.13   EB, NCI-H460, NCI-H345       305697   AA814956       EST singleton (not in UniGene) with exon   2.13   NCI-H520, NCI-H460, NCI-358       327809           CH.05_hs gi|5867968   2.13   HT29, PC3, OVCA-R       325092   T10115   Hs.92423   ESTs   2.13   HT29, NCI-358, MB-MDA-231       322299   AI971935   Hs.252784   ESTs   2.13   PRSC_con, DU145, DU145       312145   AA029526   Hs.126706   ESTs   2.12   OVCA-R, A549, MB-MDA-435s       323704   AA319421   Hs.193577   ESTs   2.12   Caco2, LnCap, OVCA-R       328971           CH.08_hs gi|6478806   2.12   NCI-358, NCI-H23, NCI-H520       325338           CH.11_hs gi|5866883   2.12   LnCap, NCI-H69, NCI-H345       331332   AA282554   Hs.89034   ESTs   2.12   NCI-H520, NCI-H23, Caco2       327159           CH.01_hs gi|5867550   2.12   EB, DU145, PC3       335180           CH22_FGENES.505_2   2.12   LnCap, NCI-H69, A549       338062           CH22_EM:AC005500.GENSCAN.162-3   2.12   PRSC_con, PRSC_log, NCI-H69       318350   AI636018   Hs.135538   ESTs   2.12   EB, HT29, DU145       312070   AW293140   Hs.108790   ESTs   2.11   Caco2, NCI-H23, A549       328314           CH.07_hs gi|5868371   2.11   HT29, NCI-H23, NCI-H460       315869   AI033547   Hs.132826   ESTs   2.11   BT474, CALU6, MCF7       339246           CH22_BA354|12.GENSCAN.5-9   2.11   CALU6, CALU6, BT474       329921           CH.16_p2 gi|6165205   2.11   BT474, MB-MDA-231, HT29       324981   Z25333   Hs.4947   ESTs   2.11   A549, NCI-H460, NCI-H520       331291   AAI59323   Hs.109929   ESTs   2.11   NCI-H345, A549, PRSC_con       332729   AA058907   Hs.83190   fatty acid synthase   2.11   NCI-358, LnCap, MB-MDA-453       325448           CH.12_hs gi|5866941   2.11   DU145, MCF7, CALU6       314929   AW188286   Hs.143612   ESTs   2.1   EB, BT474, MB-MDA-231       301063   AI057634   Hs.124596   ESTs   2.1   NCI-H23, NCI-H460, BT474       301952   A5029016   Hs.117333   KIAA1093 protein   2.1   OVCA-R, A549, CALU6       326309           CH.17_hs gi|5867277   2.1   MB-MDA-435s, NCI-H69, MB-MDA-453       315406   AI823453   Hs.146625   ESTs   2.1   OVCA-R, DU145, EB       302376   AB007867   Hs.200480   KIAA0407 protein   2.1   OVCA-R, Caco2, HT29       312181   AA417281   Hs.191595   ESTs   2.1   OVCA-R, A549, DU145       334254           CH22_FGENES.366_4   2.1   LnCap, OVCA-R, DU145       318073   AW167087   Hs.131562   ESTs   2.1   A549, CALU6, EB       304724   AA569881   Hs.65114   keratin 18   2.1   NCI-H23, NCI-H520, NCI-H460       332359   W87704   Hs.211558   ESTs   2.1   MB-MDA-435s, PRSC_con, NCI-H460       331884   AA431302   Hs.98721   EST: Weakly similar to N-copine [ H. sapie     2.1   NCI-H345, MB-MDA-231, PRSC_con       308226   AI559106   Hs.181165   eukaryotic translation elongation factor   2.1   EB, CALU6, OVCA-R       324279   AA501412   Hs.191688   ESTs; Weakly similar to Pro-Pol-dUTPase   2.09   OVCA-R, LnCap, PC3       337203           CH22_.FGENES.591-3   2.09   NCI-H69, NCI-H345, MB-MDA-231       322346   AA227618   Hs.10882   HMG-box containing protein 1   2.09   HT29, BT474, MB-MDA-231       304470   AA426654   Hs.195188   glyceraldehyde-3-phosphate dehydrogenase   2.09   NCI-H23, CALU6, NCI-H520       325977           CH.16_hs gi|6249602   2.09   NCI-H23, NCI-H520, HT29       304696   AA554758       EST singleton (not in UniGene) with exon   2.09   MB-MDA-435s, NCI-H23, BT474       317412   AI301528   Hs.132604   ESTs   2.09   Caco2, EB, NCI-358       315570   AI860360   Hs.160316   ESTs   2.08   PRSC_con, PRSC_log, NCI-H345       327341           CH.01_hs gi|6017016   2.08   MB-MDA-231, PRSC_con, NCI-H69       327431           CH.02_hs gi|5867754   2.08   NCI-H23, NCI-358, NCI-H520       314685   AI870811   Hs.158709   ESTs; Weakly similar to KIAA0938 protein   2.08   MB-MDA-453, MCF7, OVCA-R       328624           CH.07_hs gi|5868246   2.08   MCF7, NCI-358, RPWE-2       303596   AW303377       EST cluster (not in UniGene) with exon h   2.08   RPWE-2, PRSC_con, PRSC_log       336717           CH22_FGENES.81-1   2.08   BT474, HT29, MCF7       317370   AW204139   Hs.174424   ESTs; Weakly similar to p140mDia [ M. musc     2.08   NCI-H23, NCI-H460, NCI-H69       331287   AA149061   Hs.172971   ESTs   2.08   OVCA-R, EB, NCI-H345       304211   N62228       EST singleton (not in UniGene) with exon   2.08   BT474, MCF7, MB-MDA-231       315613   AW137420   Hs.192311   ESTs   2.08   PRSC_con, PRSC_log, PRSC_log       325636           CH.14_hs gi|5867002   2.08   NCI-358, NCI-H460, MB-MDA-453       336406           CH22_FGENES.823_21   2.08   HT29, EB, DU145       301714   F06529       EST cluster (not in UniGene) with exon h   2.08   LnCap, PRSC_log, PRSC_con       300496   R45159   Hs.221804   ESTs   2.08   PRSC_con, LnCap, RPWE-2       318970   R21114   Hs.21383   ESTs   2.08   NCI-H23, NCI-H520, NCI-H460       334115           CH22_FGENES.330_115   2.08   BT474, NCI-H69, HT29       308082   AI473682       EST singleton (not in UniGene) with exon   2.08   MB-MDA-435s, NCI-H345, MB-MDA-231       308282   AI569456       EST singleton (not in UniGene) with exon   2.08   LnCap, EB, PRSC_con       313038   AW451618   Hs.124195   ESTs   2.07   NCI-H345, PRSC_con, LnCap       317974   AW444468   Hs.144900   ESTs   2.07   NCI-358, NCI-H23, NCI-H520       324063   AW292740   Hs.254815   ESTs   2.07   Caco2, NCI-358, NCI-H520       334759           CH22_FGENES.428_8   2.07   CALU6, HT29, NCI-H520       307864   AI367417       EST singleton (not in UniGene) with exon   2.07   NCI-H460, NCI-358, NCI-H423       304356   AA196027   Hs.195188   glyceraldehyde-3-phosphate dehydrogenase   2.07   HT29, MCF7, MB-MDA-435s       303929   AW470753       EST singleton (not in UniGene) with exon   2.07   NCI-H345, PRSC_con, RPWE-2       331857   AA421160   Hs.9456   SWI/SNF related; matrix assocd; actin de   2.07   EB, A549, PC3       322814   AI824495   Hs.211038   ESTs   2.06   PRSC_con, RPWE-2, Caco2       303650   AA430709       EST cluster (not in UniGene) with exon h   2.06   RPWE-2, NCI-H345, PRSC_con       333403           CH22_FGENES.144_21   2.06   OVCA-R, CALU6, PC3       313663   AI953261   Hs.169813   ESTs   2.06   NCI-H345, OVCA-R, NCI-H23       338594           CH22_EM:AC005500.GENSCAN.435-4   2.06   DU145, LnCap, EB       334676           CH22_FGENES.418_29   2.06   NCI-H69, PRSC_log, PRSC_con       310046   AI198032   Hs.210356   ESTs   2.06   MB-MDA-435s, NCI-H23, Caco2       309169   AI949216       EST singleton (not in UniGene) with exon   2.06   CALU6, EB, NCI-358       329752           CH.14_p2 gi|6065777   2.06   CALU6, HT29, DU145       325085   T10001   Hs.4188   ESTs   2.06   EB, OVCA-R, MB-MDA-435s       332062   AA521016   Hs.185375   ESTs   2.06   OVCA-R, MB-MDA-453, MCF7       302074   AA382871   Hs.132794   phosphate cytidylyltransferase 1; cholin   2.06   LnCap, EB, NCI-H69       326344           CH.17_hs gi|6525295   2.06   HT29, BT474, MB-MDA-453       330855   AA079318       zm98c2.s1 Stratagene colon HT29 (#937221   2.06   RPWE-2, LnCap, PRSC_con                   IMAGE:545954 3′, mRNA seq       302525   AF024690   Hs.248056   G protein-coupled receptor 43   2.05   NCI-358, NCI-H23, DU145       331903   AA436673   Hs.29417     H sapiens  mRNA; cDNA DKFZp586B0323   2.05   Caco2, DU145, A549                   (from       316322   AW296618   Hs.120637   ESTs   2.05   BT474, MB-MDA-453, OVCA-R       321525   H78875       EST cluster (not in UniGene)   2.05   NCI-H23, PRSC_con, NCI-H520       305071   AA640579       EST singleton (not in UniGene) with exon   2.05   MB-MDA-231, BT474, HT29       326033           CH.17_hs gi|5867178   2.05   HT29, DU145, BT474       334730           CH22_FGENES.424_5   2.05   BT474, EB, OVCA-R       305335   AA704235       EST singleton (not in UniGene) with exon   2.05   MCF7, OVCA-R, MB-MDA-453       320521   N31464   Hs.24743   ESTs   2.05   MB-MDA-453, MB-MDA-231, PC3       333515           CH22_FGENES.172_5   2.04   NCI-H345, RPWE-2, PRSC_con       311020   AI918672   Hs.213783   ESTs   2.04   NCI-H460, NCI-H23, NCI-H520       324323   AA393739       EST cluster (not in UniGene)   2.04   OVCA-R, PC3, LnCap       305486   AA748889       EST singleton (not in UniGene) with exon   2.04   NCI-H345, PRSC_log, CALU6       312162   T91823       EST cluster (not in UniGene)   2.04   NCI-H520, NCI-H23, NCI-358       330980   H28794   Hs.6659   ESTs   2.04   MCF7, MB-MDA-453, MB-MDA-435s       317463   AA927290   Hs.130462   ESTs   2.04   NCI-H23, Caco2, NCI-H69       303460   AA700155   Hs.117900   ESTs   2.04   DU145, EB, CALU6       337435           CH22_FGENES.766-2   2.03   NCI-H345, OVCA-R, LnCap       305464   AA742425       EST singleton (not in UniGene) with exon   2.03   CALU6, NCI-H520, NCI-358       307918   AI383496       EST singleton (not in UniGene) with exon   2.03   NCI-H23, BT474, MB-MDA-231       322209   H89360       EST cluster (not in UniGene)   2.03   DU145, OVCA-R, MB-MDA-453       310295   AW205198   Hs.149146   ESTs   2.03   NCI-H23, NCI-H460, NCI-358       325886           CH.16_hs gi|5867087   2.03   NCI-H345, NCI-H345, RPWE-2       329719           CH.14_.p2 gi|6065785   2.03   NCI-H69, RPWE-2, PRSC_con       309247   AI972768       EST singleton (not in UniGene) with exon   2.03   LnCap, PRSC_con, RPWE-2       328277           CH.07_hs gi|6004471   2.03   LnCap, RPWE-2, A549       307296   AI205705   Hs.147222   EST   2.03   NCI-H460, NCI-358, NCI-H23       327203           CH.01_hs gi|5867447   2.03   HT29, BT474, MB-MDA-231       306866   AI086683       EST singleton (not in UniGene) with exon   2.03   BT474, NCI-H345, HT29       333339           CH22_FGENES.139_8   2.03   HT29, DU145, CALU6       323115   AI921875       EST cluster (not in UniGene)   2.03   BT474, BT474, MB-MDA-231       304811   AA584361       EST singleton (not in UniGene) with exon   2.03   NCI-H23, NCI-358, NCI-H460       323372   AL135125   Hs.13913   ESTs   2.02   DU145, EB, A549       312854   AA828713       EST cluster (not in UniGene)   2.02   NCI-H345, PRSC_con, PRSC_log       307904   AI381019       EST singleton (not in UniGene) with exon   2.02   HT29, MCF7, MB-MDA-453       332099   AA608983       afsd4.s1 Soares_testis_NHT  H sapiens  cDN   2.02   PRSC_con, NCI-H345, RPWE-2       324634   AI684571   Hs.175831   ESTs   2.02   NCI-H460, Caco2, NCI-358       335721           CH22_FGENES.599_24   2.02   NCI-H69, PRSC_log, NCI-H345       312452   AI692643   Hs.172749   ESTs   2.02   HT29, Caco2, MB-MDA-231       325396           CH.12_hs gi|5866921   2.01   HT29, NCI-H520, NCI-H450       328770           CH.07_hs gi|6017031   2.01   NCI-H23, NCI-H460, NCI-358       335585           CH22_FGENES.581_24   2.01   MB-MDA-453, DU145, MCF7       335634           CH22_FGENES.584_14   2.01   NCI-H23, NCI-H460, NCI-H69       338271           CH22_EM:AC005500.GENSCAN.287-1   2.01   MCF7, DU145, PC3       328607           CH.07_hs gi|5868233   2.01   NCI-H460, NCI-H23, NCI-358       307050   AI147341   Hs.146734   EST   2.01   NCI-H520, NCI-H23, NCI-358       334946           CH22_FGENES.465_13   2.01   CALU6, BT474, DU145       319793   R56360       EST cluster (not in UniGene)   2.01   NCI-H460, HT29, NCI-358       307223   AI193698   Hs.184776   ribosomal protein L23a   2.01   NCI-358, NCI-H520, NCI-H23       312627   AA344698   Hs.133169   ESTs   2.01   PC3, LnCap, MB-MDA-231       329221           CH.X_hs gi|5868727   2.01   NCI-H345, NCI-H69, NCI-358       305145   AA653589       EST singleton (not in UniGene) with exon   2.01   LnCap, EB, OVCA-R       328428           CH.07_hs gi|5868417   2.01   NCI-H69, MB-MDA-453, BT474       305990   AA888866   Hs.125919   EST   2.01   NCI-H520, NCI-358, NCI-H23       319368   R00003   Hs.133171   ESTs   2   OVCA-R, LnCap, PC3       324805   AA927002   Hs.131350   ESTs   2   NCI-H460, NCI-H23, NCI-358       301138   AA719179   Hs.189419   ESTs   2   NCI-H69, NCI-H23, PRSC_con       304675   AA541740       EST singleton (not in UniGene) with exon   2   NCI-H460, NCI-H520, MB-MDA-231       326194           CH.17_hs gi|5867213   2   HT29, NCI-358, 87474                    
     [0331]               TABLE 5                          H chip - B survivor vs Met query - up in Mets                                 Pkey   Ex Accn   UniG_ID   Complete_Title   Ratio Met/B surv.                                         102193   U20758   Hs. 313   secreted phosphoprotein 1 (osteopontin;   5.56       128530   AA504343   Hs. 183475     Homo sapiens  clone 25061 mRNA sequence   4.62       129093   AA262710   Hs. 108614   KIAA0627 protein   4.23       124690   R05818   Hs. 173830   ESTs   3.96       115558   AA393806   Hs. 1010   regulator of mitotic spindle assembly 1   3.39       134261   AA227678   Hs. 8084   Humn DNA sequence from clone 465N24 on c   3.22       104792   AA029288   Hs. 29147   ESTs; Highly similar to ZINC FINGER PROT   3.17       133770   M69197   Hs. 242279   haptoglobin-related protein   3.07                                                    
     [0332]               TABLE 6                          H chip - B survivor vs Met query - down in Mets                                 Pkey   Ex Accn   UniG_ID   Complete_Title   Ratio Met/B surv.                                         100116   D00654   Hs. 77443   actin; gamma 2; smooth muscle; enteric   0.07       101923   S75256       HNL = neutrophil lipocalin [human, ovarian   0.2       129982   M87789   Hs. 140   immunoglobulin gamma 3 (Gm marker)   0.2       130064   T67053   Hs. 181125   immunoglobulin lambda gene cluster   0.2                                                    
     [0333]               TABLE 7                          I chip - B survivor vs Met query - up in Mets                                 Pkey   Ex_Accn   UniG_ID   Title   Ratio Met/B surv                                         319379   T91443   Hs. 193963   ESTs   19.65       321920   N63915           11.9       324302   AA543008   Hs. 136806   ESTs; Weakly similar to !!!! ALU SUBFAMI   9.31       314522   AI732331   Hs. 187750   ESTs; Moderately similar to !!!! ALU CLA   5.79       331433   H68097   Hs. 161023   EST   4.79       324643   AI436356   Hs. 130729   ESTs   4.59       332471   AA416967   Hs. 120980   nuclear receptor co-repressor 2   4.58       314915   AA573072   Hs. 187748   ESTs; Weakly similar to !!!! ALU SUBFAMI   4.3       321354   AA078493       EST cluster (not in UniGene)   4.26       322309   AF086372       EST cluster (not in UniGene)   3.89       325100   T10265   Hs. 116122   ESTs; Weakly similar to coded for by C.   3.81       314071   AA192455   Hs. 188690   ESTs   3.74       315178   AW362945   Hs. 162459   ESTs   3.66       330987   H40988   Hs. 131965   ESTs; Weakly similar to !!!! ALU SUBFAMI   3.51       337898           CH22_EM: AC005500.GENSCAN.56-5   3.21       319403   T98413       EST cluster (not in UniGene)   3.2       331469   N22273   Hs. 39140   ESTs   3.15       331549   N56866   Hs. 237507   EST   3.14       331644   T99544   Hs. 173734   ESTs; Weakly similar to !!!! ALU CLASS B   3.14       313220   AI971981   Hs. 118241   ESTs   3.04                                                    
     [0334]               TABLE 8                          I chip - B survivor vs Met query - down in Mets                                 Pkey   Ex_Accn   UniG_ID   Title   Ratio Met/B surv                                         333658           CH22_FGENES.241_4   0.06       333657           CH22_FGENES.241_2   0.07       333654           CH22_FGENES.240_2   0.07       332859           CH22_FGENES.27_2   0.07       333656           CH22_FGENES.240_4   0.07       304480   AA430373       EST singleton (not in UniGene) with exon   0.08       333737           CH22_FGENES.261_1   0.09       308601   AI719930       EST singleton (not in UniGene) with exon   0.1       334030           CH22_FGENES.320_2   0.1       333637           CH22_FGENES.229_2   0.13       302347   AF039400   Hs. 194659   chloride channel; calcium activated; fam   0.16       333653           CH22_FGENES.239_2   0.16       333635           CH22_FGENES.228_2   0.19       333647           CH22_FGENES.235_2   0.19       307588   AI285535       EST singleton (not in UniGene) with exon   0.2       337954           CH22_EM: AC005500.GENSCAN.96-3   0.2       333588           CH22_FGENES.206_2   0.21       320244   AA296922   Hs. 129778   gastrointestinal peptide   0.22       333642           CH22_FGENES.231_2   0.23       337951           CH22_EM: AC005500.GENSCAN.94-1   0.23       333730           CH22_FGENES.258_1   0.23       333646           CH22_FGENES.234_2   0.24                                                    
     [0335]               TABLE 9                          H chip - B survivor vs Met query - up in Mets                                                 Median Mets AI vs       Pkey   Ex Accn   UniGID   Complete_Title   Median B-Sur AI                                         100655   HG2841-HT2970       Albumin, Alt. Splice 5   11.98       124875   R70506   Hs. 207693   ESTs; Weakly similar to !!!! ALU SUBFAMI   9.21       102193   U20758   Hs. 313   secreted phosphoprotein 1 (osteopontin;   6.73       100654   HG2841-HT2969       Albumin, Alt. Splice 3, Missplicing In Alloalbumin Venezia   6.18       118828   N79496   Hs. 50824   EST   5.93       128046   AA873285   Hs. 137947   ESTs   5.9       128896   D14446   Hs. 107   fibrinogen-like 1   5.17       127917   AA211895   Hs. 118831   EST; Highly similar to dJ1163J1.2.1 [H.s   5.11       125090   T91518       ye20f05.s1 Stratagene lung (#937210) Hom   4.47       118579   N68905       small inducible cytokine A5 (RANTES)   4.23       123526   AA608657       ESTs; Moderately similar to !!!! ALU SUB   4.21       128062   AA379500   Hs. 193155   ESTs   4.14       119174   R71234       yi54c08.s1 Soares placenta Nb2HP Homo sa   4.11       128530   AA504343   Hs. 183475     Homo sapiens  clone 25061 mRNA sequence   4.09       119404   T92950       ye27c10.s1 Stratagene lung (#937210) Hom   3.98       118475   N66845   Hs. 165411   ESTs; Weakly similar to !!!! ALU CLASS B   3.96       129974   K00629   Hs. 199300   Human kpni repeat mma (cdna clone pcd-k   3.87       108888   AA135606   Hs. 189384   ESTs; Weakly similar to !!!! ALU SUBFAMI   3.85       123963   C13961   Hs. 210115   EST   3.8       123523   AA608588   Hs. 193634   ESTs   3.76       128230   AA984074   Hs. 176757   ESTs   3.75       124090   H09570   Hs. 143032   ESTs; Weakly similar to neuronal thread   3.67       124690   R05818   Hs. 173830   ESTs   3.58       134261   AA227678   Hs. 8084   Human DNA sequence from clone 465N24 on   3.57       126917   AA176225   Hs. 193929   ESTs   3.52       126050   H27267   Hs. 75860   hydroxyacyl-Coenzyme A dehydrogenase/3-k   3.45       126649   AA856990   Hs. 125058   ESTs   3.42       115096   AA255991   Hs. 175319   ESTs   3.4       129906   H39216   Hs. 239970   ESTs; Weakly similar to ZNF91L [ H.sapien     3.38       123022   AA480909       aa28f10.s1 NCI_CGAP_GCB1  Homo sapiens  cD   3.38       106145   AA424791   Hs. 5734   KIAA0679 protein   3.38       125191   W67257   Hs. 138871   ESTs; Weakly similar to !!!! ALU CLASS B   3.36       108836   AA132061   Hs. 222727   ESTs; Weakly similar to ubiquitous TPR m   3.3       128710   J04813   Hs. 104117   cytochrome P450; subfamily IIIA (niphedi   3.27       123460   AA598981   Hs. 251122   EST   3.25       133735   AC002045   Hs. 251928   nuclear pore complex interacting protein   3.24       124696   R06273   Hs. 186467   ESTs; Moderately similar to !!!! ALU SUB   3.24       120748   AA303153   Hs. 237994   EST; Weakly similar to !!!! ALU SUBFAMIL   3.21       133770   M69197   Hs. 242279   haptoglobin-related protein   3.17       128336   AI242720   Hs. 146043   ESTs; Weakly similar to alternatively sp   3.14       135357   AA235803   Hs. 79572   cathepsin D (lysosomal aspartyl protease   3.12       128088   R02443   Hs. 186467   ESTs; Moderately similar to !!!! ALU SUB   3.08       124055   F10904   Hs. 100516     Homo sapiens  clone 23605 mRNA sequence   3.06       124896   R82063   Hs. 101594   EST   3.06       127598   AA610677   Hs. 168851   ESTs   3.04       116802   H44061   Hs. 194026   ESTs   3.01                                                    
     [0336]               TABLE 10                          H chip - B survivor vs Met query - Down in Mets                                 Pkey   Ex Accn   UniG_ID   Complete_Title   Ratio Met/B surv.                                         100116   D00654   Hs. 77443   actin; gamma 2; smooth muscle; enteric   0.09       130064   T67053   Hs. 181125   immunoglobulin lambda gene cluster   0.11       129982   M87789   Hs. 140   immunoglobulin gamma 3 (Gm marker)   0.12       131219   C00476   Hs. 24395   small inducible cytokine subfamily B (Cy   0.13       133806   M12759   Hs. 76325   Human Ig J chain gene   0.17       132982   L02326   Hs. 198118   immunoglobulin lambda-like polypeptide 2   0.18       131713   X57809   Hs. 181125   immunoglobulin lambda gene cluster   0.18       131791   S71043   Hs. 32225   immunoglobulin alpha 1   0.2       133725   V00563   Hs. 179543   immunoglobulin mu   0.22       101923   S75256       HNL = neutrophil lipocalin [human, ovarian   0.23       101461   M22430   Hs. 76422   phospholipase A2; group IIA (platelets;   0.24       103448   X99133   Hs. 204238   lipocalin 2 (oncogene 24p3)   0.24                                                    
     [0337]               TABLE 11                          H chip - Met vs Normal query - up in Mets                                                 Median Mets Al vs       Pkey   Ex Accn   UniG_ID   Complete_Title   Median Normal Al                                         100655   HG2841-HT2970       Albumin, Alt. Splice 5   15.91       102193   U20758   Hs. 313   secreted phosphoprotein 1 (osteopontin;   6.83       124875   R70506   Hs. 207693   ESTs; Weakly similar to !!!! ALU SUBFAMI   6.68       100654   HG2841-HT2969       Albumin, Alt. Splice 3, Missplicing In Alloalbumin Venezia   5.28       124059   F13673   Hs. 99769   ESTs   5.11       128896   D14446   Hs. 107   fibrinogen-like 1   5.05       134453   X70683   Hs. 83484   SRY (sex determining region Y)-box 4   4.82       131564   AA491465   Hs. 28792   ESTs   4.78       127917   AA211895   Hs. 118831   EST; Highly similar to dJ1163J1.2.1 [H.s   4.76       115096   AA255991   Hs. 175319   ESTs   4.67       104558   R56678   Hs. 88959   Human DNA sequence from clone 967N21 on   4.63       123526   AA608657       ESTs; Moderately similar to !!!! ALU SUB   4.61       125090   T91518       ye20f05.s1 Stratagene lung (#937210) Hom   4.59       129666   M77349   Hs. 118787   transforming growth factor, beta-induced   4.58       118828   N79496   Hs. 50824   EST   4.56       128046   AA873285   Hs. 137947   ESTs   4.45       133421   AA436560   Hs. 7327   claudin 1   4.09       129158   J05257   Hs. 109   dipeptidase 1 (renal)   4.04       128062   AA379500   Hs. 193155   ESTs   4.03       124696   R06273   Hs. 186467   ESTs; Moderately similar to !!!! ALU SUB   4.01       118475   N66845   Hs. 165411   ESTs; Weakly similar to !!!! ALU CLASS B   3.96       104755   AA024482   Hs. 9029   DKFZP434G032 protein   3.83       104978   AA088458   Hs. 19322   ESTs   3.74       118579   N68905       small inducible cytokine A5 (RANTES)   3.7       123796   AA620390   Hs. 247444   ESTs   3.62       127240   AA888387   Hs. 243845   ESTs; Moderately similar to !!!! ALU SUB   3.61       104105   AA422123   Hs. 42457   ESTs   3.55       129349   D86974   Hs. 110613   KIAA0220 protein   3.54       119329   T51832       ESTs; Moderately similar to !!!! ALU SUB   3.53       114617   AA084148   Hs. 110659   ESTs   3.52       123143   AA487595       aa95e2.s1 Stratagene fetal retina 93722   3.48       103119   X63629   Hs. 2877   cadherin 3; P-cadherin (placental)   3.48       119404   T92950       ye27c10.s1 Stratagene lung (#937210) Hom   3.47       123963   C13961   Hs. 210115   EST   3.47       116480   C14088   Hs. 195188   glyceraldehyde-3-phosphate dehydrogenase   3.4       108836   AA132061   Hs. 222727   ESTs; Weakly similar to ubiquitous TPR m   3.39       120748   AA303153   Hs. 237994   EST; Weakly similar to !!!! ALU SUBFAMIL   3.38       133770   M69197   Hs. 242279   haptoglobin-related protein   3.38       132358   X60486   Hs. 46423   H4 histone family; member G   3.37       127759   AI369384       arylsulfatase D   3.37       129095   L12350   Hs. 108623   thrombospondin 2   3.37       128261   AI061213   Hs. 13179   ESTs; Moderately similar to !!!! ALU SUB   3.36       126908   AA169866       ESTs; Weakly similar to !!!! ALU SUBFAMI   3.36       128954   N32118   Hs. 209100   DKFZP434C171 protein   3.34       119174   R71234       yi54c08.s1 Soares placenta Nb2HP Homo sa   3.33       106687   AA463234   Hs. 119387   KIAA0792 gene product   3.32       128230   AA984074   Hs. 176757   ESTs   3.3       126649   AA856990   Hs. 125058   ESTs   3.25       124620   N74051   Hs. 194092   ESTs; Weakly similar to !!!! ALU SUBFAMI   3.24       135427           AFFX control: human alu repeats   3.23       129967   H99653   Hs. 138618   ESTs   3.22       125191   W67257   Hs. 138871   ESTs; Weakly similar to !!!! ALU CLASS B   3.2       124684   R02401   Hs. 221078   ESTs   3.2       128010   AA856953   Hs. 23348   S-phase kinase-associated protein 2 (p45   3.17       119423   T99544   Hs. 173734   ESTs; Weakly similar to !!!! ALU CLASS B   3.16       123022   AA480909       aa28f10.s1 NCI_CGAP_GCB1  Homo sapiens  cD   3.15       103654   Z70759         H. sapiens  mitochondrial 16S rRNA gene (p   3.13       128336   AI242720   Hs. 146043   ESTs; Weakly similar to alternatively sp   3.12       124690   R05818   Hs. 173830   ESTs   3.1       129791   F02778   Hs. 173887   KIAA0876 protein   3.07       114472   AA028924   Hs. 177407   ESTs; Weakly similar to !!!! ALU SUBFAMI   3.07       115429   AA284139   Hs. 89295   EST   3.06       130020   AA433930   Hs. 240443   ESTs; Weakly similar to !!!! HNK-1 sulfotrans   3.06       126050   H27267   Hs. 75860   hydroxyacyl-Coenzyme A dehydrogenase/3-k   3.05       129906   H39216   Hs. 239970   ESTs; Weakly similar to ZNF91L [H.sapien   3.04       123422   AA598484   Hs. 238476   EST   3.03       103059   X57351   Hs. 174195   interferon induced transmembrane protein   3.02       124253   H69742   Hs. 102201   ESTs   3.02       123523   AA608588   Hs. 193634   ESTs   3.02       132669   AA188378   Hs. 54602   ESTs; Weakly similar to 60S RIBOSOMAL PR   3.02       123196   AA489250   Hs. 59403   serine palmitoyltransferase; subunit II   3.01       122948   AA477483       zu44h2.s1 Soares ovary tumor NbHOT Homo   3.01       119053   R11501       yf28f1.s1 Soares fetal liver spleen 1NFL   3.01       125953   H40829       yo05d11.r1 Soares adult brain N2b5HB55Y   3       119155   R61715   Hs. 138237   ESTs   3                                                    
     [0338]               TABLE 12                          H chip - Met vs Normal query - down in Mets                                 Pkey   Ex Accn   UniG_ID   Complete_Title   Median Mets Al vs Median Normal Al                                         103466   Y00339   Hs. 155097   carbonic anhydrase II   0.01       104258   AF007216   Hs. 5462   solute carrier family 4; sodium bicarbon   0.02       108999   AA156064   Hs. 72115   ESTs   0.04       101046   K01160       Accession not listed in Genbank   0.04       133565   H57056   Hs. 204831   ESTs   0.05       101346   L76465   Hs. 77348   hydroxyprostaglandin dehydrogenase 15-(N   0.05       123137   AA487468   Hs. 100686   ESTs; Weakly similar to secreted cement   0.05       134534   X73501   Hs. 84905     H. Sapiens  mRNA for cytokeratin 20   0.05       118823   N79237   Hs. 50813   ESTs; Weakly similar to long chain fatty   0.06       102095   U11313   Hs. 75760   sterol carrier protein 2   0.06       111855   R37362   Hs. 21351   ESTs   0.06       129105   AA224351   Hs. 108681   ESTs   0.07       130320   U19495   Hs. 237356   stromal cell-derived factor 1   0.07       113778   W15263   Hs. 5422   ESTs   0.07       116786   H25836   Hs. 83429   tumor necrosis factor (ligand) superfami   0.07       100116   D00654   Hs. 77443   actin; gamma 2; smooth muscle; enteric   0.07       104636   AA004415   Hs. 106106   ESTs   0.07       107032   AA599472   Hs. 247309   succinate-CoA ligase; GDP-forming; beta   0.08       106605   AA457718   Hs. 21103     Homo sapiens  mRNA; cDNA DKFZp564B076 (fr   0.08       128906   AA487557   Hs. 10706   ESTs   0.08       130016   AA055811   Hs. 143131   transmembrane glycoprotein   0.08       113523   T90037   Hs. 16686   ESTs   0.08       102638   U67319   Hs. 9216   caspase 7; apoptosis-related cysteine pr   0.09       124308   H93575   Hs. 227146     Homo sapiens  mRNA; cDNA DKFZp564J142 (fr   0.09       129519   AA298786   Hs. 112242   ESTs   0.09       134749   L10955   Hs. 89485   carbonic anhydrase IV   0.09       130366   L11708   Hs. 155109   hydroxysteroid (17-beta) dehydrogenase 2   0.09       109272   AA195718   Hs. 86030   ESTs   0.09       102124   U14528   Hs. 29981   solute carrier family 26 (sulfate transp   0.1       132711   N73702   Hs. 238927   ESTs   0.1       131861   D11925   Hs. 184245   KIAA0929 protein Msx2 interacting nuclea   0.1       133806   M12759   Hs. 76325   Human Ig J chain gene   0.1       102571   U60115         Homo sapiens  skeletal muscle LIM-protein   0.1       114846   AA234929   Hs. 44343   ESTs   0.11       131328   V01512   Hs. 25647   v-fos FBJ murine osteosarcoma viral onco   0.11       106569   AA455983   Hs. 117816   sorcin   0.11       103542   Z11793   Hs. 3314   selenoprotein P; plasma; 1   0.11       128915   C02386   Hs. 107139   ESTs   0.11       120914   AA377254   Hs. 97107   EST   0.11       130867   J04093   Hs. 2056   UDP glycosyltransferase 1   0.11       110837   N30796   Hs. 17424   ESTs; Weakly similar to semaphorin F [H.   0.12       101877   M97496   Hs. 778   guanylate cyclase activator 1B (retina)   0.12       132617   AA171913   Hs. 5338   carbonic anhydrase XII   0.12       129113   AA147646   Hs. 108740   DKFZP586A0522 protein   0.12       133435   T23983   Hs. 7365   ESTs   0.13       132836   F09557   Hs. 57929   slit (Drosophila) homolog 3   0.13       125832   AA628600   Hs. 117587   ESTs   0.13       104613   AA001049   Hs. 24713     Homo sapiens  mRNA; cDNA DKFZp586G0123 (f   0.13       132903   AA235404   Hs. 5985     Homo sapiens  clone 25186 mRNA sequence   0.13       119479   W32094   Hs. 55501   ESTs   0.14       131273   AA421139   Hs. 173542   ESTs   0.14       106674   AA461303   Hs. 7946   DKFZP586D1519 protein   0.14       108980   AA151676   Hs. 33455   peptidyl arginine deiminase; type II   0.14       103211   X73079   Hs. 205126   polymeric immunoglobulin receptor   0.14       131219   C00476   Hs. 24395   small inducible cytokine subfamily B (Cy   0.15       116459   AA621399   Hs. 64193   ESTs   0.15       130219   R77539   Hs. 15285   ESTs   0.15       113863   W68388   Hs. 21288   ESTs; Weakly similar to KIAA0704 protein   0.15       101564   M32886   Hs. 117816   sorcin   0.15       109502   AA233837   Hs. 44755   ESTs; Weakly similar to membrane glycopr   0.15       107222   D51235   Hs. 82689   tumor rejection antigen (gp96) 1   0.15       135237   AA454930   Hs. 9691   ESTs   0.15       112483   R66534   Hs. 28403   ESTs   0.15       132387   R70914   Hs. 8997   heat shock 70 kD protein 1   0.15       130343   AA490262   Hs. 15485   ESTs; Weakly similar to APICAL-LIKE PROT   0.16       105496   AA256323   Hs. 25264   DKFZP434N126 protein   0.16       104037   AA372630   Hs. 100347   differentially expressed in hematopoieti   0.16       101461   M22430   Hs. 76422   phospholipase A2; group IIA (platelets;   0.16       116551   D20458   Hs. 229071   EST   0.16       133889   AA099391   Hs. 211582   myosin; light polypeptide kinase   0.16       103653   Z70295   Hs. 32966   guanylate cyclase activator 2B (uroguany   0.16       101070   L02785   Hs. 1650   down-regulated in adenoma   0.17       131501   AA121127   Hs. 181307   H3 histone; family 3A   0.17       133515   X98311   Hs. 74466   carcinoembryonic antigen-related cell ad   0.17       108604   AA099820   Hs. 49696   ESTs   0.17       132982   L02326   Hs. 198118   immunoglobulin lambda-like polypeptide 2   0.17       131676   C20785   Hs. 30514   ESTs   0.17       134675   AA250745   Hs. 87773   protein kinase; cAMP-dependent; catalyti   0.17       133441   M82962   Hs. 179704   meprin A; alpha (PABA peptide hydrolase)   0.18       130455   X17059   Hs. 155956   N-acetyltransferase 1 (arylamine N-acety   0.18       131734   D62965   Hs. 31297   ESTs   0.18       100749   HG3521-HT3715       Ras-Related Protein Rap1b   0.18       116724   F13665   Hs. 65641   ESTs   0.18       129265   X68277   Hs. 171695   dual specificity phosphatase 1   0.18       102347   U37518   Hs. 83429   tumor necrosis factor (ligand) superfami   0.18       114542   AA055768   Hs. 122576   ESTs   0.18       123900   AA621223   Hs. 112953   EST   0.19       121780   AA422086   Hs. 124660   ESTs   0.19       115662   AA405715   Hs. 64179   hypothetical protein   0.19       113803   W42789   Hs. 31446   ESTs   0.19       105493   AA256268   Hs. 10283   ESTs   0.19       113195   T57112       yc20g11.s1 Stratagene lung(#937210) Hom   0.19       129462   D84239   Hs. 111732   IgG Fc binding protein   0.19       133664   X86693   Hs. 75445   hevin   0.2       126180   R18070   Hs. 3712   ubiquinol-cytochrome c reductase; Rieske   0.2       100687   HG3115-HT3291       Golli-Mbp (Gb: L18862)   0.2       130064   T67053   Hs. 181125   immunoglobulin lambda gene cluster   0.2       101367   M12963   Hs. 73843   alcohol dehydrogenase 1 (class I); alpha   0.2       132254   L20826   Hs. 430   plastin 1 (I isoform)   0.2       105646   AA282147   Hs. 5888   ESTs   0.2       132883   AA047151   Hs. 5897     Homo sapiens  mRNA; cDNA DKFZp586P1622 (f   0.21       132618   AA253330   Hs. 5344   adaptor-related protein complex 1; gamma   0.21       108931   AA147186   Hs. 250746   ESTs   0.22       131421   X64177   Hs. 2667   metallothionein 1H   0.22       107295   T34527   Hs. 80120   UDP-N-acetyl-alpha-D-galactosamine:polyp   0.22       103576   Z26317   Hs. 2631   desmoglein 2   0.22       105173   AA182030   Hs. 8364   ESTs   0.22       134843   H60595   Hs. 90061   progesterone binding protein   0.22       102009   U02680   Hs. 82643   protein tyrosine kinase 9   0.23       123997   D51171   Hs. 78902   voltage-dependent anion channel 2   0.23       106609   AA458652   Hs. 32181   ESTs   0.23       101300   L40391   Hs. 6445     Homo sapiens  (clone s153) mRNA fragment   0.23       129717   AA481670   Hs. 12150   ESTs; Weakly similar to retinal short-ch   0.23       108565   AA085342   Hs. 1526   ATPase; Ca++ transporting; cardiac muscl   0.23       121314   AA402799   Hs. 182538   ESTs   0.23       124803   R45480   Hs. 164866   cyclin K   0.23       130208   AA620556   Hs. 15250   peroxisomal D3;D2-enoyl-CoA isomerase   0.23       132888   AA490775   Hs. 5920   UDP-N-acetylglucosamine-2-epimerase/N-ac   0.23       132720   Z69881   Hs. 5541   ATPase; Ca++ transporting; ubiquitous   0.23       102239   U26726   Hs. 1376   hydroxysteroid (11-beta) dehydrogenase 2   0.23       115764   AA421562   Hs. 91011   anterior gradient 2 (Xenepus laevis) hom   0.24       130558   H96654   Hs. 15984   ESTs; Weakly similar to gene pp21 protei   0.24       122666   AA455052   Hs. 99387   ESTs   0.24       134495   D63477   Hs. 84087   KIAA0143 protein   0.24       124017   F02202   Hs. 100960   ESTs   0.24       106925   AA491261   Hs. 37558     Homo sapiens  clone 23923 mRNA sequence   0.24       115187   AA261805   Hs. 44021   ESTs   0.24       105309   AA233790   Hs. 4104   ESTs; Weakly similar to cDNA EST yk386g7   0.24       124457   N50114   Hs. 128704   ESTs   0.24       130616   AA233763   Hs. 16726     Homo sapiens  mRNA; cDNA DKFZp564A132 (fr   0.25       105795   AA369245   Hs. 17448   ESTs; Weakly similar to !!!! ALU SUBFAMI   0.25       134579   N23222   Hs. 85963   CD36 antigen (collagen type I receptor;   0.25                                                    
     [0339]               TABLE 13                          H chip - Met vs Normal query - up in Mets                                 Pkey   Ex Accn   UniG_ID   Complete_Title   Ratio Met/Normal                                         102193   U20758   Hs. 313   secreted phosphoprotein 1 (osteopontin;   8.457       111307   N73988   Hs. 37477   ESTs; Weakly similar to CGI-141 protein   6.05       103119   X63629   Hs. 2877   cadherin 3; P-cadherin (placental)   5.207       131564   AA491456   Hs. 28792   ESTs   5.136       119729   W69747   Hs. 94806   KIAA1062 protein   4.667       124059   F13673   Hs. 99769   ESTs   4.398       123987   C21171   Hs. 95497   ESTs; Weakly similar to GLUCOSE TRANSPOR   4.292       128817   N47524   Hs. 28491   spermidine/spermine N1-acetyltransferase   3.964       133770   M69197   Hs. 242279   haptoglobin-related protein   3.823       130412   AA406554   Hs. 241572   golgi autoantigen; golgin subfamily a; 5   3.719       104755   AA024482   Hs. 9029   DKFZP434G032 protein   3.702       132676   AA283035   Hs. 54813   ESTs   3.645       134453   X70683   Hs. 83484   SRY (sex determining region Y)-box 4   3.581       124690   R05818   Hs. 173830   ESTs   3.446       106949   AA496805   Hs. 177425   KIAA0964 protein   3.42       130724   AA370091   Hs. 179680   ESTs   3.402       128992   R49693   Hs. 107708   ESTs   3.32       133421   AA436560   Hs. 7327   claudin 1   3.255       103047   X55990   Hs. 73839   ribonuclease; RNase A family; 3 (eosinop   3.229       102990   X51441   Hs. 181062   serum amyloid A1   3.149       115429   AA284139   Hs. 89295   EST   3.114       129158   J05257   Hs. 109   dipeptidase 1 (renal)   3.019       123533   AA608751   Hs. 244904   ESTs; Weakly similar to !!!! ALU SUBFAMI   3.011                                                    
     [0340]               TABLE 14                          H chip - Met vs Normal query - down in Mets                                 PkeyY   Ex Accn   UniG_ID   Complete_Title   Ratio Met/Normal                                         103466   Y00339   Hs. 155097   carbonic anhydrase II   0.012       104258   AF007216   Hs. 5462   solute carrier family 4; sodium bicarbon   0.025       108999   AA156064   Hs. 72115   ESTs   0.034       101046   K01160       Accession not listed in Genbank   0.041       133565   H57056   Hs. 204831   ESTs   0.042       101346   L76465   Hs. 77348   hydroxyprostaglandin dehydrogenase 15-(N   0.043       102095   U11313   Hs. 75760   sterol carrier protein 2   0.054       111855   R37362   Hs. 21351   ESTs   0.055       130320   U19495   Hs. 237356   stromal cell-derived factor 1   0.058       123137   AA487468   Hs. 100686   ESTs; Weakly similar to secreted cement   0.06       107222   D51235   Hs. 82689   tumor rejection antigen (gp96) 1   0.06       102638   U67319   Hs. 9216   caspase 7; apoptosis-related cysteine pr   0.063       128906   AA487557   Hs. 10706   ESTs   0.065       129105   AA224351   Hs. 108681   ESTs   0.069       110837   N30796   Hs. 17424   ESTs; Weakly similar to semaphorin F [H.   0.069       100116   D00654   Hs. 77443   actin; gamma 2; smooth muscle; enteric   0.071       116786   H25836   Hs. 83429   tumor necrosis factor (ligand) superfami   0.074       130867   J04093   Hs. 2056   UDP glycosyltransferase 1   0.075       132836   F09557   Hs. 57929   slit (Drosophila) homolog 3   0.076       131861   D11925   Hs. 184245   KIAA0929 protein Msx2 interacting nuclea   0.081       106674   AA461303   Hs. 7946   DKFZP586D1519 protein   0.084       109272   AA195718   Hs. 86030   ESTs   0.088       132711   N73702   Hs. 238927   ESTs   0.091       106569   AA455983   Hs. 117816   sorcin   0.092       104636   AA004415   Hs. 106106   ESTs   0.093       118823   N79237   Hs. 50813   ESTs; Weakly similar to long chain fatty   0.094       134534   X73501   Hs. 84905   H. Sapiens mRNA for cytokeratin 20   0.095       119479   W32094   Hs. 55501   ESTs   0.096       113778   W15263   Hs. 5422   ESTs   0.098       128482   U83908   Hs. 100407   programmed cell death 4   0.102       124653   N92884   Hs. 109641   ESTs   0.106       133407   AA093348   Hs. 7306   secreted frizzled-related protein 1   0.108       135237   AA454930   Hs. 9691   ESTs   0.109       116250   AA480975   Hs. 44829   ESTs   0.111       132617   AA171913   Hs. 5338   carbonic anhydrase XII   0.112       131273   AA421139   Hs. 173542   ESTs   0.113       116710   F10577   Hs. 70312   ESTs   0.114       131791   S71043   Hs. 32225   immunoglobulin alpha 1   0.114       112483   R66534   Hs. 28403   ESTs   0.115       132017   W67251   Hs. 37331     Homo sapiens  vav 3 oncogene (VAV3) mRNA   0.116       124308   H93575   Hs. 227146     Homo sapiens  mRNA; cDNA DKFZp564J142 (fr   0.117       114846   AA234929   Hs. 44343   ESTs   0.119       116551   D20458   Hs. 229071   EST   0.12       105299   AA233511   Hs. 194720   ATP-binding cassette; sub-family G (WHIT   0.122       130366   L11708   Hs. 155109   hydroxysteroid (17-beta) dehydrogenase 2   0.122       133806   M12759   Hs. 76325   Human Ig J chain gene   0.122       104776   AA026349   Hs. 31412   ESTs   0.125       129565   X77777   Hs. 198726   vasoactive intestinal peptide receptor 1   0.125       131272   AA423884   Hs. 139033   paternally expressed gene 3   0.127       105774   AA348014   Hs. 23412   ESTs   0.128       134604   M22995   Hs. 865   RAP1A; member of RAS oncogene family   0.128       134711   X04011   Hs. 88974   cytochrome b-245; beta polypeptide (chro   0.128       129113   AA147646   Hs. 108740   DKFZP586A0522 protein   0.133       123995   D51119   Hs. 100090   tetraspan 3   0.133       129168   T90621   Hs. 109052   chromosome 14 open reading frame 2   0.133       123891   AA621103   Hs. 99216   ESTs; Moderately similar to !!!! ALU SUB   0.135       132694   M60830   Hs. 5509   ecotropic viral integration site 2B   0.135       135342   W60097   Hs. 99120   DEAD/H (Asp-Glu-Ala-Asp/His) box polypep   0.135       131510   AA207114   Hs. 27842   ESTs; Weakly similar to similar to 1-acy   0.137       133652   AA287383   Hs. 7540   ESTs   0.137       134749   L10955   Hs. 89485   carbonic anhydrase IV   0.139       106586   AA456598   Hs. 256269   ESTs   0.139       106893   AA489636   Hs. 25253   ESTs   0.139       101070   L02785   Hs. 1650   down-regulated in adenoma   0.14       114293   Z40718   Hs. 20196   adenylate cyclase 9   0.14       113966   W86600   Hs. 9842   ESTs   0.141       101185   L19872   Hs. 170087   aryl hydrocarbon receptor   0.145       131492   AA393876   Hs. 1255   nuclear receptor subfamily 2; group F; m   0.145       133889   AA099391   Hs. 211582   myosin; light polypeptide kinase   0.145       120914   AA377254   Hs. 97107   EST   0.147       118771   N74690   Hs. 50547   ESTs   0.149       105496   AA256323   Hs. 25264   DKFZP434N126 protein   0.151       131011   R41771   Hs. 22146   ESTs   0.153       106210   AA428239   Hs. 10338   ESTs   0.154       114069   Z38161   Hs. 197335   plasma glutamate carboxypeptidase   0.154       133011   AA042990   Hs. 171921   sema domain; immunoglobulin domain (Ig);   0.154       115967   AA446887   Hs. 42911   ESTs   0.154       102571   U60115         Homo sapiens  skeletal muscle LIM-protein   0.155       100687   HG3115-HT3291       Golli-Mbp (Gb: L18862)   0.155       132903   AA235404   Hs. 5985     Homo sapiens  clone 25186 mRNA sequence   0.155       125832   AA628600   Hs. 117587   ESTs   0.155       130064   T67053   Hs. 181125   immunoglobulin lambda gene cluster   0.157       123264   AA491003   Hs. 99824   BCE-1 protein   0.159       130919   AA291710   Hs. 21276   collagen; type IV; alpha 3 (Goodpasture   0.159       103542   Z11793   Hs. 3314   selenoprotein P; plasma; 1   0.161       101478   M23379   Hs. 758   RAS p21 protein activator (GTPase activa   0.162       108921   AA142913   Hs. 71721   ESTs   0.164       100642   HG2743-HT3926       Caldesmon 1, Alt. Splice 6, Non-Muscle   0.167       132109   AA599801   Hs. 40098   ESTs   0.167       115719   AA416997   Hs. 59622   ESTs   0.169       128915   C02386   Hs. 107139   ESTs   0.171       117634   N36421   Hs. 107854   ESTs; Weakly similar to SODIUM-AND CHLO   0.172       129462   D84239   Hs. 111732   IgG Fc binding protein   0.174       131328   V01512   Hs. 25647   v-fos FBJ murine osteosarcoma viral onco   0.176       130343   AA490262   Hs. 15485   ESTs; Weakly similar to APICAL-LIKE PROT   0.177       115764   AA421562   Hs. 91011   anterior gradient 2 (Xenepus laevis) hom   0.177       122261   AA436830   Hs. 98902   ESTs   0.179       106605   AA457718   Hs. 21103     Homo sapiens  mRNA; cDNA DKFZp564B076 (fr   0.179       109991   H09813   Hs. 12896   KIAA1034 protein   0.181       101300   L40391   Hs. 6445     Homo sapiens  (clone s153) mRNA fragment   0.181       123080   AA485303   Hs. 205126   polymeric immunoglobulin receptor   0.182       130016   AA055811   Hs. 143131   transmembrane glycoprotein   0.186       122666   AA455052   Hs. 99387   ESTs   0.188       105453   AA252893   Hs. 9001   ESTs   0.189       108980   AA151676   Hs. 33455   peptidyl arginine deiminase; type II   0.19       100248   D31888   Hs. 78398   KIAA0071 protein   0.192       130036   AA195260   Hs. 206738   ESTs; Moderately similar to !!!! ALU SUB   0.192       110882   N36001   Hs. 17348   ESTs; Weakly similar to !!!! ALU SUBFAMI   0.193       131676   C20785   Hs. 30514   ESTs   0.195       111029   N54792   Hs. 24697   cytidine monophosphate-N-acetylneuramini   0.196       131257   AA256042   Hs. 24908   ESTs   0.196       133348   T23517   Hs. 7149   ESTs   0.196       133784   AA214305   Hs. 76173   ESTs   0.196       113863   W68388   Hs. 21288   ESTs; Weakly similar to KIAA0704 protein   0.197       103158   X67235   Hs. 118651   hematopoietically expressed homeobox   0.198       102347   U37518   Hs. 83429   tumor necrosis factor (ligand) superfami   0.2       111351   N90223   Hs. 23392   ESTs   0.2       123495   AA599850   Hs. 106747   ESTs; Weakly similar to similar to BPTV   0.2       123802   AA620448   Hs. 61408     Homo sapiens  clone 24760 mRNA sequence   0.2       129243   H88033   Hs. 109727   KIAA0733 protein   0.2       130219   R77539   Hs. 15285   ESTs   0.2       131171   H04644   Hs. 167619   ESTs; Weakly similar to !!!! ALU SUBFAMI   0.2       133746   U44378   Hs. 75862   MAD (mothers against decapentaplegic; Dr   0.2       116459   AA621399   Hs. 64193   ESTs   0.201       109613   F03031   Hs. 27519   ESTs   0.202       133435   T23983   Hs. 7365   ESTs   0.202       103002   X52001   Hs. 1408   endothelin 3   0.204       125153   W38294       Accession not listed in Genbank   0.204       131919   AA121266   Hs. 34641   ESTs   0.204       100749   HG3521-HT3715       Ras-Related Protein Rap1b   0.205       105085   AA147537   Hs. 4811   ESTs   0.208       124571   N67470   Hs. 173074   DKFZP564O1863 protein   0.21       129519   AA298786   Hs. 112242   ESTs   0.21       116724   F13665   Hs. 65641   ESTs   0.21       132932   T15482   Hs. 6093   ESTs   0.21       113803   W42789   Hs. 31446   ESTs   0.211       110792   N24899   Hs. 6630   ESTs   0.212       105178   AA187490   Hs. 21941   ESTs   0.212       107295   T34527   Hs. 80120   UDP-N-acetyl-alpha-D-galactosamine: polyp   0.212       115262   AA279112   Hs. 88594   ESTs   0.213       115839   AA429038   Hs. 40541   ESTs   0.213       103211   X73079   Hs. 205126   polymeric immunoglobulin receptor   0.214       108604   AA099820   Hs. 49696   ESTs   0.215       105173   AA182030   Hs. 8364   ESTs   0.217       108539   AA084677   Hs. 54558   ESTs; Weakly similar to protein B [H.sap   0.217       109984   H09594   Hs. 10299   ESTs   0.217       133536   Y00264   Hs. 177486   amyloid beta (A4) precursor protein (pro   0.217       129965   T71333   Hs. 13854   ESTs   0.219       114542   AA055768   Hs. 122576   ESTs   0.219       132982   L02326   Hs. 198118   immunoglobulin lambda-like polypeptide 2   0.22       101809   M86849         Homo sapiens  connexin 26 (GJB2) mRNA, co   0.222       105795   AA369245   Hs. 17448   ESTs; Weakly similar to !!!! ALU SUBFAMI   0.222       132119   H99211   Hs. 40334   ESTs   0.222       132733   R25385   Hs. 123654   KIAA0824 protein   0.222       109415   AA227219   Hs. 110826   trinucleotide repeat containing 9   0.222       113083   T40530   Hs. 8241   ESTs; Weakly similar to heat shock prote   0.223       107053   AA600147   Hs. 5741   ESTs; Weakly similar to NADH-cytochrome   0.224       103653   Z70295   Hs. 32966   guanylate cyclase activator 2B (uroguany   0.225       104613   AA001049   Hs. 24713     Homo sapiens  mRNA; cDNA DKFZp586G0123 (f   0.225       126180   R18070   Hs. 3712   ubiquinol-cytochrome c reductase; Rieske   0.227       132015   D11900   Hs. 3731   ESTs   0.227       130616   AA233763   Hs. 16726     Homo sapiens  mRNA; cDNA DKFZp564A132 (fr   0.227       132883   AA047151   Hs. 5897     Homo sapiens  mRNA; cDNA DKFZp586P1622 (f   0.23       123169   AA488892   Hs. 104472   ESTs; Weakly similar to Gag-Pol polyprot   0.233       115187   AA261805   Hs. 44021   ESTs   0.234       116787   H28581   Hs. 15641   ESTs   0.234       113195   T57112       yc20g11.s1 Stratagene lung (#937210) Hom   0.235       130707   W45457   Hs. 203559   ESTs   0.235       124803   R45480   Hs. 164866   cyclin K   0.235       116844   H64938   Hs. 38331   ESTs   0.235       102759   U81607   Hs. 788   A kinase (PRKA) anchor protein (gravin)   0.238       130584   AA009839   Hs. 180841   tumor necrosis factor receptor superfami   0.238       133240   D31161   Hs. 68613   ESTs   0.238       132952   AA425154   Hs. 61426   ESTs   0.239       132720   Z69881   Hs. 5541   ATPase; Ca++ transporting; ubiquitous   0.24       131734   D62965   Hs. 31297   ESTs   0.24       111890   R38678   Hs. 12365   ESTs   0.241       102325   U35139   Hs. 50130   necdin (mouse) homolog   0.244       104968   AA084602   Hs. 29669   ESTs   0.244       105674   AA284755   Hs. 214742   CDW52 antigen (CAMPATH-1 antigen)   0.244       120519   AA258585   Hs. 129887   cadherin 19 (NOTE: redefinition of symbo   0.244       134675   AA250745   Hs. 87773   protein kinase; cAMP-dependent; catalyti   0.244       130642   M63438   Hs. 156110   Immunoglobulin kappa variable 1D-8   0.245       134418   R78190   Hs. 82933   ESTs; Weakly similar to cDNA EST EMBL: T0   0.245       115137   AA257976   Hs. 56156   ESTs   0.245       131713   X57809   Hs. 181125   immunoglobulin lambda gene cluster   0.246       108931   AA147186   Hs. 250746   ESTs   0.246       106609   AA458652   Hs. 32181   ESTs   0.248       115559   AA393810   Hs. 41067   ESTs   0.25       133985   L34657   Hs. 78146   platelet/endothelial cell adhesion molec   0.25       134088   D43636   Hs. 79025   KIAA0096 protein   0.25       134487   R38185   Hs. 83954     Homo sapiens  unknown mRNA   0.25                                                    
     [0341]               TABLE 15                          I chip - Met vs Normal query - up in Mets                                 Pkey   Ex_Accn   UniG_ID   Title   Ratio Met/Normal                                         319379   T91443   Hs. 193963   ESTs   18.71       321920   N63915       EST cluster (not in UniGene)   11.9       314522   AI732331   Hs. 187750   ESTs; Moderately similar to !!!! ALU CLA   7.23       315720   AW291875   Hs. 163900   ESTs   6.06       308010   AI439190   Hs. 181165   eukaryotic translation elongation factor   5.76       313774   AW136836   Hs. 144583   ESTs   5.01       300734   AW205197   Hs. 240951   ESTs   3.98       337895           CH22_EM: AC005500.GENSCAN.56-2   3.98       312339   AA524394       EST cluster (not in UniGene)   3.66       331644   T99544   Hs. 173734   ESTs; Weakly similar to !!!! ALU CLASS B   3.53       324643   AI436356   Hs. 130729   ESTs   3.52       324302   AA543008   Hs. 136806   ESTs; Weakly similar to !!!! ALU SUBFAMI   3.41       314912   AI431345   Hs. 161784   ESTs   3.33       319403   T98413       EST cluster (not in UniGene)   3.32       308676   AI761036       EST singleton (not in UniGene) with exon   3.27       331858   AA421163   Hs. 163848   ESTs   3.22       315178   AW362945   Hs. 162459   ESTs   3.21       321354   AA078493       EST cluster (not in UniGene)   3.18       337898           CH22_EM: AC005500.GENSCAN.56-5   3.16       322682   AI110679       EST cluster (not in UniGene)   3.15       313197   AI738851   Hs. 222487   ESTs   3.1       308991   AI879831       EST singleton (not in UniGene) with exon   3.08       310016   AW449612   Hs. 152475   ESTs   3.05                                                    
     [0342]               TABLE 16                          I chip - Met vs Normal query - down in Mets                                 Pkey   Ex_Accn   UniG_ID   title   Ratio Met/Normal                                         303041   AF127035       EST cluster (not in UniGene) with exon h   0.02       302360   AJ010901   Hs. 198267   mucin 4; tracheobronchial   0.03       301948   AA344647   Hs. 116724   aldo-keto reductase family 1; member B11   0.03       336091           CH22_FGENES.689_3   0.04       333657           CH22_FGENES.241_2   0.04       333658           CH22_FGENES.241_4   0.04       333737           CH22_FGENES.261_1   0.05       333656           CH22_FGENES.240_4   0.05       302347   AF039400   Hs. 194659   chloride channel; calcium activated; fam   0.06       336084           CH22_FGENES.688_13   0.06       330385   AA449749   Hs. 31386   ESTs; Highly similar to secreted apoptos   0.06       304487   AA434241       EST singleton (not in UniGene) with exon   0.07       302292   AF067797       EST cluster (not in UniGene) with exon h   0.07       334030           CH22_FGENES.320_2   0.07       332859           CH22_FGENES.27_2   0.07       333654           CH22_FGENES.240_2   0.07       303270   AL120518   Hs. 105352   ESTs   0.08       320352   Y13323   Hs. 145296   disintegrin protease   0.08       333637           CH22_FGENES.229_2   0.08       324094   AA382603       EST cluster (not in UniGene)   0.08       320590   U67058   Hs. 168102   Human proteinase activated receptor-2 mR   0.08       330622   X63597   Hs. 2996   sucrase-isomaltase   0.08       331441   H75860   Hs. 39720   ESTs   0.08       308601   AI719930       EST singleton (not in UniGene) wilh exon   0.09       323770   AA722425       EST cluster (not in UniGene)   0.09       335188           CH22_FGENES.507_3   0.09       333730           CH22_FGENES.258_1   0.09       304480   AA430373       EST singleton (not in UniGene) with exon   0.09       336081           CH22_FGENES.688_10   0.1       332071   AA598594   Hs. 112475   ESTs   0.1       318538   N28625   Hs. 74034   caveolin 1; caveolae protein; 22 kD   0.1       311331   AI679622   Hs. 32225   immunoglobulin alpha 1   0.1       319668   NM_002731       EST cluster (not in UniGene)   0.11       332567   N23730   Hs. 25647   v-fos FBJ murine osteosarcoma viral onco   0.11       319395   AW062570   Hs. 13809   ESTs   0.11       315594   AI983437   Hs. 155145   ESTs   0.11       321539   N98619   Hs. 62461   ARP2 (actin-related protein 2; yeast) ho   0.12       333647           CH22_FGENES.235_2   0.12       333588           CH22_FGENES.206_2   0.12       321286   AI380940       EST cluster (not in UniGene)   0.12       320727   U96044       EST cluster (not in UniGene)   0.13       335687           CH22_FGENES.596_2   0.13       324611   AA743462   Hs. 165337   ESTs   0.14       335115           CH22_FGENES.496_2   0.14       324660   AA541644   Hs. 186044   ESTs   0.14       337951           CH22_EM: AC005500.GENSCAN.94-1   0.14       302332   AI833168   Hs. 184507     Homo sapiens  Chromosome 16 BAC clone CIT   0.14       300921   AW293224   Hs. 232165   ESTs   0.14       333646           CH22_FGENES.234_2   0.14       335116           CH22_FGENES.496_3   0.14       320211   AL039402   Hs. 125783   DEME-6 protein   0.15       336092           CH22_FGENES.689_6   0.15       330673   D57823   Hs. 92962   Sec23 ( S. cerevisiae ) homolog A   0.16       303042   AF129532       EST cluster (not in UniGene) with exon h   0.16       337954           CH22_EM: AC005500.GENSCAN.96-3   0.16       336645           CH22_FGENES.26-1   0.16       335651           CH22_FGENES.590_2   0.16       314499   AL044570   Hs. 147975   ESTs   0.17       336124           CH22_FGENES.701_9   0.17       315199   AA877996   Hs. 125376   ESTs   0.17       324525   AW044647   Hs. 196284   ESTs   0.17       320825   NM_004751       EST cluster (not in UniGene)   0.18       302049   AA377072   Hs. 129792     Homo sapiens  Chromosome 16 BAC clone CIT   0.18       336083           CH22_FGENES.688_12   0.18       333653           CH22_FGENES.239_2   0.18       323243   W44372       EST cluster (not in UniGene)   0.19       316610   AW087973   Hs. 126731   ESTs   0.19       315033   AI493046   Hs. 146133   ESTs   0.19       330551   U39840   Hs. 105440   hepatocyte nuclear factor 3; alpha   0.19       333642           CH22_FGENES.231_2   0.19       301281   AA843986   Hs. 190586   ESTs   0.2       333626           CH22_FGENES.224_2   0.21       303792   C75094   Hs. 199839   ESTs; Highly similar to NG22 [ H. sapiens ]   0.21       332325   T79428   Hs. 191264   ESTs   0.21       321223   AA431366       EST cluster (not in UniGene)   0.21       333635           CH22_FGENES.228_2   0.22       314645   AI808999   Hs. 207570   ESTs   0.22       322929   AI365585   Hs. 146246   ESTs   0.22       324718   AI557019   Hs. 116467   ESTs   0.22       335652           CH22_FGENES.590_3   0.22       307783   AI347274       EST singleton (not in UniGene) with exon   0.22       331344   AA357927   Hs. 70208   ESTs   0.22       336088           CH22_FGENES.688_17   0.23       320802   D83824   Hs. 185055   BENE protein   0.23       335692           CH22_FGENES.596_7   0.23       333593           CH22_FGENES.210_2   0.23       335667           CH22_FGENES.590_18   0.24       314853   AA729232   Hs. 153279   ESTs   0.24       320244   AA296922   Hs. 129778   gastrointestinal peptide   0.24       300601   AI762130   Hs. 165619   ESTs   0.24       305080   AA641485       EST singleton (not in UniGene) with exon   0.25       335189           CH22_FGENES.507_4   0.25                                                    
     [0343]               TABLE 17                          B survivor vs Mets - Up in B survivor                                 Pkey   Ex Accn   UniG_ID   Complete Title   Ratio BS/Met                                         101006   J04132   Hs. 97087   CD3Z antigen; zeta polypeptide (TiT3 com   7.28       114173   Z39050   Hs. 21963   ESTs   6.13       130284   X82206   Hs. 153961   ARP1 (actin-related protein 1; yeast) ho   5.77       100787   HG3872-HT4142       Immunoglobulin Gamma Heavy Chain, V(6)Djc Regions (Gb: U13200)   5.63       132461   AA405775   Hs. 49005   hypothetical protein   5.62       133806   M12759   Hs. 76325   Human Ig J chain gene   5.46       133747   D86972   Hs. 75863   KIAA0218 gene product   5.45       123328   AA496968   Hs. 105403   EST   5.28       132671   X76302   Hs. 54649   putative nucleic acid binding protein RY   5.25       132018   AA293194   Hs. 3737   ESTs   5.22       100186   D17516   Hs. 4748   adenylate cyclase activating polypeptide   5.14       107155   AA621202   Hs. 7946   DKFZP586D1519 protein   5.1       103566   Z22555   Hs. 180616   CD36 antigen (collagen type I receptor;   5.06       113355   T79203   Hs. 14480   ESTs   4.99       129040   U38864   Hs. 108139   zinc finger protein 212   4.96       130214   H78003   Hs. 15266   ESTs   4.93       129550   AA480991   Hs. 113025   ESTs   4.92       129704   W81301   Hs. 12064   ubiquitin specific protease 22   4.91       116425   AA609574   Hs. 51483   ESTs   4.77       105166   AA179787   Hs. 30570   polyglutamine binding protein 1   4.65       118765   N74442   Hs. 183696   ESTs   4.6       108999   AA156064   Hs. 72115   ESTs   4.57       112756   R93908   Hs. 35258   ESTs   4.54       111655   R16884   Hs. 187462   ESTs   4.48       119392   T90672   Hs. 238859   ESTs   4.42       131957   AA609008   Hs. 183232   ESTs   4.41       129275   D82061   Hs. 109993   Ke6 gene; mouse; human homolog of   4.4       113634   T95085   Hs. 125182   ESTs   4.4       127187   AA297138   Hs. 207422   ESTs   4.32       101147   L13266   Hs. 105   glutamate receptor; ionotropic; N-methyl   4.3       134901   S78873   Hs. 90875   RAB interacting factor   4.26       100896   HG4593-HT4998       Sodium Channel 1   4.24       100687   HG3115-HT3291       Golli-Mbp (Gb: L18862)   4.21       129758   AA599552   Hs. 183770     Homo sapiens  mRNA; cDNA DKFZp566P2346 (f   4.19       105440   AA252243   Hs. 22851   ESTs   4.16       131551   AA127867   Hs. 28608   ESTs   4.15       113761   T99373   Hs. 189786   ESTs   4.09       105897   AA401091       ESTs   4.07       129495   AA382529   Hs. 239676   ESTs   4.06       103436   X98206         H. sapiens  mRNA for UV-B repressed sequen   4.03       104673   AA007633   Hs. 20010   ESTs   4.03       128886   L36720   Hs. 106880   bystin-like   4.02       100702   HG3236-HT3413       Neurofibromatosis 2 Tumor Suppressor (Gb: L27065)   3.99       123547   AA608820   Hs. 124085   KIAA0921 protein   3.98       134877   AA455241   Hs. 90527   ESTs   3.97       123650   AA609332   Hs. 180696   ESTs   3.94       106482   AA451672   Hs. 108824   ESTs; Weakly similar to cDNA EST yk415c1   3.94       101909   S69265         Homo sapiens  mRNA for PLE21 protein; com   3.93       108390   AA075070       zm86b6.s1 Stratagene ovarian cancer (#93   3.93                   LYMPHOCYTE ANTIGEN LY-6A.2/LY-6E.1 PREC       135403   U06643   Hs. 99923   lectin; galactoside-binding; soluble; 7   3.89       121038   AA398536   Hs. 97365   ESTs   3.88       128496   T83496   Hs. 100610   ESTs   3.86       108785   AA128946       ESTs   3.86       119838   W79499   Hs. 58580   ESTs   3.85       130109   L12060   Hs. 1497   retinoic acid receptor; gamma   3.84       134538   U79288   Hs. 85053   KIAA0513 gene product   3.83       110310   H38209   Hs. 32728   EST   3.81       110433   H49425   Hs. 32992   ESTs   3.78       111834   R36138   Hs. 152458   ESTs   3.76       130903   N27086   Hs. 21068   ESTs   3.74       105142   AA164851   Hs. 15380   ESTs; Weakly similar to HERV-E envelope   3.73       130248   U84569   Hs. 153452   chromosome 21 open reading frame 2   3.73       130645   AA020942   Hs. 17200   STAM-like protein containing SH3 and ITA   3.73       123378   AA521043   Hs. 185832   ESTs   3.73       103985   AA313880       EST185737 Colon carcinoma (HCC) cell in   3.73       112397   R60822   Hs. 26805   EST   3.72       100980   J03069   Hs. 72931   v-myc avian myelocytomatosis viral oncog   3.72       102609   U64863   Hs. 158297   programmed cell death 1   3.7       108974   AA151402   Hs. 46531   ESTs   3.7       130192   Y12661   Hs. 171014   VGF nerve growth factor inducible   3.69       131318   X51699   Hs. 2558   bone gamma-carboxyglutamate (gla) protei   3.68       113759   T99364   Hs. 16074     Homo sapiens  mRNA; cDNA DKFZp564|153 (fr   3.66       133712   L19267   Hs. 198836   dystrophia myotonica-containing WD repea   3.65       134229   R15108   Hs. 8037   ESTs   3.65       134241   AA300265   Hs. 80540   KIAA0195 gene product   3.65       124699   R06413   Hs. 112278   arrestin; beta 1   3.62       107343   U03115   Hs. 103945   Human V beta T-cell receptor (TCRBV) gen   3.62       128511   AA425636   Hs. 10082   potassium intermediate/small conductance   3.62       105466   AA253412   Hs. 21489   ESTs   3.61       131377   R41389   Hs. 26159   ESTs   3.6       119135   R49548   Hs. 169681   death effector domain-containing   3.6       132982   L02326   Hs. 198118   immunoglobulin lambda-like polypeptide 2   3.59       128514   H84261   Hs. 100843   ESTs; Weakly similar to similar to GTP-b   3.56       102396   U41804   Hs. 54411   putative T1/ST2 receptor binding protein   3.55       134945   R50247   Hs. 91600   ESTs   3.55       134913   X60483   Hs. 91031   H4 histone family; member D   3.54       102053   U07664   Hs. 37035   homeo box HB9   3.52       121569   AA412686   Hs. 97955   ESTs   3.52       132560   AA005315   Hs. 204524   ESTs; Weakly similar to KIAA0747 protein   3.51       118456   N66580   Hs. 161496   EST; Weakly similarto HC1 ORF [M.muscul   3.51       111518   R08160   Hs. 222529   ESTs; Weakly similar to !!!! ALU SUBFAMI   3.51       116795   H38858   Hs. 251783   EST   3.5       130377   AA378316   Hs. 155182   KIAA1036 protein   3.5       121774   AA421756   Hs. 98361   ESTs   3.49       123413   AA521448   Hs. 103845   ESTs   3.49       133798   AA444115   Hs. 76277   ESTs; Weakly similar to salivary proline   3.49       135183   X93996   Hs. 239663   myeloid/lymphoid or mixed-lineage leukem   3.48       132479   AA477715   Hs. 4953   golgi autoantigen; golgin subfamily a; 3   3.47       117191   H99394   Hs. 40339   EST   3.47       130942   X87852   Hs. 21432     H. sapiens  mRNA for SEX gene   3.46       130700   D55696   Hs. 18069   protease; cysteine; 1 (legumain)   3.43       131301   T17386   Hs. 164501   ESTs   3.43       100818   HG4018-HT4288       Opioid-Binding Cell Adhesion Molecule   3.43       103393   X94612   Hs. 41749   protein kinase; cGMP-dependent type II   3.43       131337   AA228116   Hs. 170204   KIAA0551 protein   3.42       133403   X68688   Hs. 72991   zinc finger protein 33b (KOX 31)   3.42       124728   R16231   Hs. 106620     Homo sapiens  clone 23950 mRNA sequence   3.41       123168   AA488881   Hs. 105218   EST   3.39       123324   AA496932   Hs. 105399   KIAA0809 protein   3.38       106947   AA496685   Hs. 37936   suppressor of variegation 3-9 (Drosophil   3.38       116717   F11065   Hs. 79363   ESTs   3.36       102794   U88629   Hs. 173334   ELL-RELATED RNA POLYMERASE II; ELONGATIO   3.34       117503   N31963   Hs. 44286   ESTs   3.33       112220   R50295   Hs. 25703   ESTs   3.33       106340   AA441792   Hs. 22857   chord domain-containing protein 1   3.33       106308   AA436186   Hs. 30662   ESTs   3.32       130894   D16105   Hs. 210   leukocyte tyrosine kinase   3.31       120039   W92548   Hs. 94985   ESTs   3.31       131428   U17838   Hs. 26719   PR domain containing 2; with ZNF domain   3.3       113285   T66830   Hs. 182712   ESTs   3.3       109458   AA232648   Hs. 87068   ESTs   3.29       132134   AA242904   Hs. 40637   proline-rich Gla (G-carboxyglutamic acid   3.29       118964   N93330   Hs. 54937     Homo sapiens  clone 24722 unknown mRNA; p   3.29       127621   AI218205   Hs. 116204   ESTs   3.29       135149   U40002   Hs. 95351   lipase; hormone-sensitive   3.28       114371   Z41835   Hs. 27810   ESTs   3.28       130043   AA055404   Hs. 193953   ESTs; Weakly similar to !!!! ALU SUBFAMI   3.27       121347   AA405181   Hs. 97972   ESTs   3.25       105754   AA302657   Hs. 192028   ESTs   3.25       121327   AA404286   Hs. 173125   peptidylprolyl isomerase F (cyclophilin   3.25       111204   N68295   Hs. 37982   ESTs   3.25       120949   AA397830   Hs. 98347   ESTs; Weakly similar to GLIOMA PATHOGENE   3.25       130024   U15197   Hs. 241560   Human histo-blood group ABO protein mRNA   3.24       125005   T61449   Hs. 193727   ESTs   3.24       121067   AA398662   Hs. 97302   ESTs   3.24       120996   AA398281   Hs. 143684   ESTs   3.23       117101   H94043   Hs. 24341   DKFZP586|1419 protein   3.23       130708   U40490   Hs. 18136   nicotinamide nucleotide transhydrogenase   3.23       130270   L40399   Hs. 153820   hypothetical protein   3.22       131605   AA256220   Hs. 29383   ESTs   3.22       100854   HG4194-HT4464       Sodium/Hydrogen Exchanger 5   3.22       123026   AA481072   Hs. 99743   ESTs   3.21       108328   AA070204       zm68b3.s1 Stratagene neuroepithelium (#9   3.2       104259   AF007833   Hs. 159265     Homo sapiens  kruppel-related zinc finger   3.2       133711   J04130   Hs. 75703   small inducible cytokine A4 (homologous   3.2       112261   R52145   Hs. 25894   ESTs; Highly similar to hypothetical pro   3.19       119529   W38053       Accession not listed in Genbank   3.19       122386   AA446221   Hs. 6092   F-box protein containing leucine-rich re   3.19       109157   AA179161   Hs. 73562   ESTs   3.19       119903   W85707   Hs. 75936   erythrocyte membrane protein band 4.9 (d   3.18       127452   AA491317       aa65c01.r1 NCI_CGAP_GCB1  Homo sapiens  cD   3.18       124229   H62793   Hs. 221892   ESTs   3.18       129221   AA417126   Hs. 109571   translocase of inner mitochondrial membr   3.17       133185   AA481404   Hs. 6686   ESTs   3.16       121479   AA411911   Hs. 98110   ESTs   3.16       133872   T79868   Hs. 180903   hypothetical protein   3.16       132504   U12897   Hs. 5022   imprinted in Prader-Willi syndrome   3.16       103089   X60382   Hs. 179729   collagen; type X; alpha 1 (Schmid metaph   3.15       129654   AA019943   Hs. 118463     H. sapiens  mRNA for unknown liver orphan   3.15       117295   N22360   Hs. 43153   ESTs   3.15       107349   U48224   Hs. 158321   beaded filament structural protein 2; ph   3.14       103451   X99459   Hs. 154782   adaptor-related protein complex 3; sigma   3.14       114854   AA235056   Hs. 120244   ESTs   3.14       121044   AA398551   Hs. 97374   ESTs   3.13       128582   U22963   Hs. 101840   major histocompatibility complex; class   3.13       112598   R78565   Hs. 138395   EST   3.13       113170   T54342   Hs. 222506   ESTs   3.13       111714   R23146   Hs. 23466   ESTs   3.13       111809   R33616   Hs. 24688   EST   3.12       115249   AA278961   Hs. 71124   ESTs   3.11       103228   X75546   Hs. 230   fibromodulin   3.11       129944   L00389   Hs. 1361   cytochrome P450; subfamily I (aromatic c   3.11       107927   AA028915   Hs. 237709   EST   3.11       130297   H94949   Hs. 171955   trophinin-assisting protein (tastin)   3.1       125742   H81181   Hs. 183654   ESTs; Weakly similar to unknown [S.cerev   3.1       134802   L35548   Hs. 89709   glutamate-cysteine ligase (gamma-glutamy   3.1       112560   R72293   Hs. 6179     Homo sapiens  mRNA; cDNA DKFZp586K2322 (f   3.1       129266   AA343881   Hs. 209061   sudD (suppressor of bimD6; Aspergillus n   3.09       126982   AA211419       small inducible cytokine A5 (RANTES)   3.09       131594   H29723   Hs. 29261   ESTs; Weakly similar to serine protease   3.08       134910   AA431320   Hs. 9100   ESTs   3.08       103505   Y09912   Hs. 33102   transcription factor AP-2 beta (activati   3.08       110525   H57330   Hs. 37430   EST   3.07       123276   AA491270   Hs. 187946   ESTs   3.06       130519   H91819   Hs. 10669   ESTs; Moderately similar to KIAA0400 [H.   3.06       126621   AA192638       zq01h08.r1 Stratagene muscle 937209 Homo   3.05       134327   AF006041   Hs. 178743   death-associated protein 6   3.04       103513   Y10209         H. sapiens  mRNA for CD3L protein   3.04       131243   R16667   Hs. 24752   spectrin SH3 domain binding protein 1   3.04       115187   AA261805   Hs. 44021   ESTs   3.04       107543   Z43703   Hs. 4552     Homo sapiens  HRIHFB2157 mRNA; partial cd   3.04       134051   S67070   Hs. 78846   heat shock 27 kD protein 2   3.04       113461   T86737   Hs. 193536   ESTs   3.03       130490   X57522   Hs. 158164   ATP-binding cassette; sub-family B (MDR/   3.03       128843   AA234141   Hs. 203004   katanin p80 (WD40-containing) subunit B   3.03       100941   HG862-HT862       Transition Protein 2   3.03       122268   AA436855   Hs. 178202   ESTs   3.02       107425   W26719   Hs. 30204   ESTs   3.02       130930   U19261       TNF receptor-associated factor 1   3.02       132958   W90398   Hs. 6147   KIAA1075 protein   3.02       100973   J02888   Hs. 73956   NAD(P)H menadione oxidoreductase 2; diox   3.01       104924   AA058532   Hs. 28774   ESTs   3.01       129998   Y10055   Hs. 162808   phosphoinositide-3-kinase; catalytic; de   3.01       130023   X13401   Hs. 239600   calmodulin-like 3   3.01       129536   M33493   Hs. 184504   tryptase; alpha   3       112015   R42836   Hs. 23198   ESTs   3       103036   X54925   Hs. 83169   matrix metalloproteinase 1 (interstitial   2.99       100756   HG3565-HT3768       Zinc Finger Protein (Gb: M88357)   2.99       103425   X97301         H. sapiens  mRNA for Ptg-11 protein   2.99       118291   N63076   Hs. 138745   EST   2.98       125877   H15229       ym30g04.r1 Soares infant brain 1NIB Homo   2.98                   repetitive element;, mRNA sequence.       101371   M13232   Hs. 36989   coagulation factor VII (serum prothrombi   2.98       102958   X15675   Hs. 93174   Human endogenous retrovirus pHE.1 (ERV9)   2.97       121183   AA400138   Hs. 97703   ESTs   2.97       119241   T12559   Hs. 221382   ESTs   2.96       115067   AA253458   Hs. 91299   postmeiotic segregation increased 2-like   2.96       126196   AA084394       zn05g10.s1 Stratagene hNT neuron (#93723   2.96       111642   R16153   Hs. 128740   ESTs; Highly similar to DNb-5 [ H. sapiens     2.95       100898   HG4638-HT5050       Spliceosomal Protein Sap 49   2.95       129370   AA287879   Hs. 110796   ESTs; Moderately similar to GTP-binding   2.94       128915   C02386   Hs. 107139   ESTs   2.94       101868   M96233   Hs. 82891   glutathione S-transferase M4   2.94       124394   N29724       gamma2-adaptin   2.93       103559   Z19585   Hs. 75774   thrombospondin 4   2.93       107882   AA025630   Hs. 17801   ESTs; Moderately similar to serine/proli   2.93       134919   T99639   Hs. 91142   KH-type splicing regulatory protein (FUS   2.92       110293   H30258   Hs. 37165   collagen; type IX; alpha 2   2.92       132433   AA082546   Hs. 48516   ESTs   2.92       127347   AA428350       ESTs   2.92       121976   AA429807   Hs. 98632   ESTs   2.91       133025   AA135492   Hs. 6318   ESTs; Highly similar to peroxisomal shor   2.91       133413   S72043   Hs. 73133   metallothionein 3 (growth inhibitory fac   2.91       111694   R22035   Hs. 23331   ESTs   2.91       128369   F12681   Hs. 205300   ESTs   2.9       102464   U49260   Hs. 3828   mevalonate (diphospho) decarboxylase   2.9       135358   C21431   Hs. 99486   ESTs; Weakly similar to aralar1 [H.sapie   2.9       108661   AA113287   Hs. 65905   ESTs; Weakly similar to PTB-ASSOCIATED S   2.9       102185   U20230       Human guanyl cyclase C gene, partial cds   2.89       122071   AA431787   Hs. 98762   EST   2.89       102040   U06088   Hs. 159479   galactosamine (N-acetyl)-6-sulfate sulfa   2.89       115689   AA410645   Hs. 199014   ESTs   2.88       135110   T15817   Hs. 193788   nitric oxide synthase 2A (inducible; hep   2.88       118729   N73717   Hs. 161526   EST   2.88       129518   AA369807   Hs. 112238   ESTs   2.88       125788   R74309   Hs. 44499   small EDRK-rich factor 2   2.87       128650   U57971   Hs. 103124   ATPase; Ca++ transporting; plasma membra   2.87       125936   H30751   Hs. 182859   lifeguard   2.87       100779   HG3731-HT4001       Immunoglobulin Heavy Chain, Vdjrc Regions (Gb: L23566)   2.87       104451   M13299   Hs. 102119   blue cone pigment   2.86       133539   M21574   Hs. 74615   platelet-derived growth factor receptor;   2.86       119506   W37833   Hs. 55563   ESTs   2.86       126568   AA190515       zp85d12.r1 Stratagene HeLa cell s3 93721   2.86       134184   X53742   Hs. 79732   fibulin 1   2.86       127633   AI339609   Hs. 152733   potassium voltage-gated channel; Isk-rel   2.86       128716   AA045978   Hs. 173611   NADH dehydrogenase (ubiquinone) Fe-S pro   2.86       107135   AA620782   Hs. 23247   ESTs   2.85       117748   N47317   Hs. 141858   ESTs   2.85       124030   F04143   Hs. 151032     Homo sapiens  clone 23856 unknown mRNA; p   2.85       135120   AA449841   Hs. 108300   NOT3 (negative regulator of transcriptio   2.84       102156   U17977       HSU17977 Humn fibroblast cDNA H sapiens   2.84       129418   AA401401   Hs. 11127   PET112 (yeast homolog)-like   2.84       103222   X74795   Hs. 77171   minichromosome maintenance deficient (S.   2.84       125145   W38001       Accession not listed in Genbank   2.83       100560   HG2228-HT2305       Crystallin, Beta B   2.83       105370   AA238476   Hs. 22791   ESTs; Weakly similar to transmembrane pr   2.83       127036   AI468598       ESTs   2.83       128788   AA029073   Hs. 105685   ESTs   2.83       119523   W38041       Accession not listed in Genbank   2.82       126436   N31224   Hs. 211579   melanoma adhesion molecule   2.82       126559   R15866   Hs. 170263   tumor protein 53-binding protein; 1   2.82       118183   N59287   Hs. 48361   EST   2.82       101298   L40387   Hs. 118633   2′-5′oligoadenylate synthetase-like   2.81       131830   U33054   Hs. 32959   G protein-coupled receptor kinase 2 (Dro   2.81       124173   H41281   Hs. 107619   ESTs   2.81       102295   U32581         Homo sapiens  KIAA0421 mRNA; partial cds   2.81       129719   N66396   Hs. 167766   ESTs; Moderately similar to Pro-a2(XI) [   2.81       126573   AA482023   Hs. 155218   E1B-55 kDa-associated protein 5   2.81       125477   AI270093   Hs. 234642   aquaporin 3   2.81       106492   AA451896   Hs. 7922   ESTs; Weakly similar to contains similar   2.8                   p19; an RNA polymerase II elongation fa       132881   T86118   Hs. 58875   ESTs   2.8       114733   AA133778   Hs. 95734   ESTs   2.79       104618   AA001611   Hs. 186494   ESTs   2.79       134137   F10045   Hs. 79347   KIAA0211 gene product   2.79       133212   U82979   Hs. 67846   leukocyte Ig-like receptor; subfamily B   2.78       100882   HG4460-HT4729       Immunoglobulin Heavy Chain, Vdjc Regions (Gb: L23564)   2.78       104756   AA024622   Hs. 15813   solute carrier family 22 (organic cation   2.78       129861   N69507   Hs. 129849   DKFZP564M182 protein   2.78       120824   AA347548   Hs. 96876   ESTs   2.78       100684   HG3107-HT3283       Plasma Membrane Calcium Pump Hpmca2a   2.78       121789   AA423970   Hs. 178111   ESTs   2.78       101847   M59941   Hs. 118200   colony stimulating factor 2 receptor; be   2.78       113722   T97957   Hs. 202948   ESTs; Weakly similar to alternatively sp   2.77       115107   AA256371   Hs. 186645   ESTs   2.77       111464   R05518   Hs. 19521   ESTs   2.77       108446   AA079120       zm95e1.s1 Stratagene colon HT29 (#937221   2.77       123921   AA621329   Hs. 250671   Hu DNA seq frm clone 1163J1 on chr 22q13   2.77                   prot (similar to mouse Celsr1; rat MEGF       134445   M59488   Hs. 83384   S100 calcium-binding protein; beta (neur   2.76       114132   Z38688   Hs. 24192   ESTs   2.76       120500   AA256430   Hs. 132525   ESTs   2.76       101860   M95610   Hs. 37165   collagen; type IX; alpha 2   2.76       134430   H52105   Hs. 8309   KIAA0747 protein   2.76       124152   H27216   Hs. 107635   ESTs   2.76       132268   AA058833   Hs. 23445   ESTs; Weakly smlr to similar to M. muscu   2.76       116257   AA481493   Hs. 88537   ESTs   2.76       102438   U46570   Hs. 7733   tetratricopeptide repeat domain 1   2.75       122393   AA446334   Hs. 99064   ESTs   2.75       107653   AA010210   Hs. 47041   ESTs   2.75       123674   AA609473   Hs. 105187   ESTs; Moderately similar to kinesin like   2.75       129858   T66906   Hs. 12970   ESTs   2.75       130117   U06641   Hs. 150207   UDP glycosyltransferase 2 family; polype   2.75       133464   M13982   Hs. 73917   interleukin 4   2.75       127039   AA233366   Hs. 256491   ESTs   2.74       128318   AA418202   Hs. 13810   ESTs   2.74       123363   AA504818   Hs. 171279   ESTs   2.74       127654   AA649249   Hs. 75640   natriuretic peptide precursor A   2.74       132067   L20860   Hs. 178382   glycoprotein Ib (platelet); beta polypep   2.74       125664   AA948418   Hs. 25744   ESTs; Weakly similar to Ydr412wp [S.cere   2.73       132354   L05187   Hs. 211913   small proline-rich protein 1A   2.73       101568   M33764   Hs. 75212   ornithine decarboxylase 1   2.73       101438   M20777   Hs. 159263     Homo sapiens ; alpha-2 (VI) collagen   2.73       116233   AA479082   Hs. 61142   ESTs   2.73       122194   AA435882   Hs. 97531   ESTs   2.72       113995   W88466   Hs. 22010   ESTs   2.72       124251   H68286   Hs. 107924   ESTs   2.71       120583   AA281304   Hs. 78614   complement component 1; q subcomponent b   2.71       134958   U72507   Hs. 234216   Human 40871 mRNA partial sequence   2.71       124280   H85835   Hs. 100058   dihydropyrimidinase-like 4   2.71       130113   M64673   Hs. 1499   heat shock transcription factor 1   2.71       106588   AA456612   Hs. 25682   ESTs; Weakly smlr to PHOSPHATIDYLETHANOL   2.71       132023   F01927   Hs. 3743   ESTs; Weakly similar to proline-rich pro   2.7       112284   R53558   Hs. 26052   ESTs   2.7       107897   AA026240   Hs. 61387   ESTs   2.7       122610   AA453598   Hs. 99336   ESTs   2.7       119070   R27788   Hs. 52302   ESTs   2.7       103491   Y08836         Homo sapiens  mRNA for HRX-like protein   2.7       108225   AA058843   Hs. 161620   EST   2.7       105829   AA398290   Hs. 21965   ESTs   2.69       127749   AI251757   Hs. 145234   ESTs   2.69       128428   AI185718   Hs. 143900   ESTs   2.69       108409   AA075578       zm88h3.s1 Stratagene ovarian cancer (#93   2.69       114739   AA134923   Hs. 103833   ESTs; Weakly similar to predicted using   2.68       128821   D87002   Hs. 135   multiple UniGene matches   2.68       107412   W26105   Hs. 8961   ESTs   2.68       117012   H85893   Hs. 194387   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.68       135262   AA416551   Hs. 9732   ESTs   2.68       105367   AA236397   Hs. 20304   ESTs   2.68       134771   L13939   Hs. 89576   adaptor-related protein complex 1; beta   2.68       105036   AA128617   Hs. 25549   ESTs   2.68       125093   T92930   Hs. 186750   ESTs   2.68       119340   T61899   Hs. 90677   ESTs; Highly similar to CGI-82 protein [   2.67       132603   H62900   Hs. 53066   hsp70-interacting protein   2.67       113733   T98386   Hs. 184548   ESTs   2.67       123564   AA608902   Hs. 112612   ESTs   2.66       116059   AA454165   Hs. 53455   ESTs   2.66       125803   R79373   Hs. 29852   ESTs   2.66       123012   AA479962   Hs. 139636   EST   2.66       106080   AA418046   Hs. 35124   ESTs   2.66       128809   T59668   Hs. 102267   lysyl oxidase   2.66       104354   H08988   Hs. 113759   ESTs   2.66       107068   AA609028   Hs. 8032   ESTs   2.65       101418   M17754   Hs. 1276   BN51 (BHK21) temperature sensitivity com   2.65       135157   AA460138   Hs. 95582   SRY (sex-determining region Y)-box 20   2.65       123312   AA496258   Hs. 99601   ESTs   2.65       130034   C00350   Hs. 14454   chromosome 2 open reading frame 1   2.65       103897   AA248870   Hs. 55058   ESTs   2.65       117771   N47961   Hs. 46794   ESTs   2.65       109980   H09529   Hs. 98693   DKFZP586J0917 protein   2.64       121966   AA429653   Hs. 98616   EST   2.64       114233   Z39652   Hs. 27457   ESTs   2.64       129594   R70379   Hs. 115396   Human germline IgD chain gene; C-region;   2.63       102319   U34587   Hs. 66578   corticotropin releasing hormone receptor   2.63       111700   R22212   Hs. 23361   ESTs   2.63       127365   AA001628   Hs. 74335   heat shock 90 kD protein 1; beta   2.63       104205   AA496240   Hs. 17270   DKFZP434C211 protein   2.63       124559   N66223   Hs. 135928   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.63       106351   AA442772   Hs. 191987   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.63       121903   AA427605   Hs. 258742   myosin-binding protein C; cardiac   2.62       116442   AA620310   Hs. 184343   ESTs; Weakly similar to KIAA0585 protein   2.62       127041   F06090       HSC0WG031 normalized infant brain cDNA H   2.62       132860   U93049   Hs. 58435   FYN-binding protein (FYB-120/130)   2.62       131591   L22454   Hs. 180069   nuclear respiratory factor 1   2.61       118118   N56901   Hs. 47995   ESTs   2.61       134809   X52611   Hs. 18387   transcription factor AP-2 alpha (activat   2.61       117706   N45091   Hs. 46472   ESTs   2.61       127488   AA312179   Hs. 178617   ESTs; Weakly similar to CGI-82 protein [   2.61       114891   AA235984   Hs. 87469   ESTs   2.6       116426   AA609668   Hs. 71657   ESTs   2.6       132589   AA432197   Hs. 5260   ESTs; Weakly similar to CGI-08 protein [   2.6       128410   AA452788       zx39g11.r1 Soares_total_fetus_Nb2HF8_9w   2.6       106081   AA418394   Hs. 25354   ESTs   2.6       129919   R02003   Hs. 191208   ESTs; Weakly similar to weak similarity   2.59       124672   R00307   Hs. 188504   ESTs   2.59       122758   AA459013   Hs. 99742   X-ray repair complementing defective rep   2.59       125656   AA040118   Hs. 78687   neutral sphingomyelinase (N-SMase) activ   2.59       130052   J00220   Hs. 145288   Human Ig active epsilon1 5′ UT; V-D-J re   2.59       134878   U28055   Hs. 250826   macrophage stimulating; pseudogene 9   2.59       131908   L05624   Hs. 3446   mitogen-activated protein kinase kinase   2.59       126470   AA843339   Hs. 193168   ESTs; Weakly similar to CGI-52 protein [   2.59       132353   M31651   Hs. 46319   sex hormone-binding globulin   2.58       119588   W44559   Hs. 142525   ESTs   2.58       131757   D17532   Hs. 316   DEAD/H (Asp-Glu-Ala-Asp/His) box polypep   2.58       118114   N56875   Hs. 143212   cystatin F (leukocystatin)   2.58       128200   AI279952   Hs. 158037   ESTs; Weakly similar to transcription re   2.58       131208   C14586   Hs. 24220     Homo sapiens  mRNA; cDNA DKFZp566M051 (fr   2.58       124721   R11131   Hs. 154966   ESTs   2.57       108706   AA121820         Homo sapiens  mRNA for KIAA0842 protein;   2.57       118831   N79592   Hs. 50838   ESTs   2.57       115708   AA412212   Hs. 44033   ESTs   2.57       107233   D59322   Hs. 22595   ESTs   2.57       129559   AA234945   Hs. 11360   ESTs   2.57       126953   AA743849   Hs. 127286   ESTs   2.56       108165   AA055221   Hs. 63168   ESTs   2.56       104069   AA401547   Hs. 172694   ESTs   2.56       112146   R46512   Hs. 25374   ESTs   2.56       108364   AA074891   Hs. 124917   ESTs; Highly similar to KIAA0838 protein   2.56       131779   R49047   Hs. 179779   ribosomal protein L37   2.56       111829   R36070   Hs. 25079   EST   2.55       103424   X97267   Hs. 155975   protein tyrosine phosphatase; receptor t   2.55       100133   D13118   Hs. 80986   ATP synthase; H+ transporting; mitochond   2.55       130208   AA620556   Hs. 15250   peroxisomal D3;D2-enoyl-CoA isomerase   2.55       124649   N92593   Hs. 102907   ESTs   2.55       106511   AA452865   Hs. 206713   UDP-Gal: betaGlcNAc beta 1;4-galactosylt   2.55       128467   AA176446   Hs. 180428   ESTs; Weakly similar to hypothetical 43.   2.55       113524   T90072   Hs. 15060   ESTs   2.55       107821   AA020991   Hs. 172856   ESTs   2.55       111900   R39044   Hs. 25318     Homo sapiens  clone 25194 mRNA sequence   2.54       109908   H05255   Hs. 203237   EST   2.54       132069   D87454   Hs. 192966   KIAA0265 protein   2.54       130660   T95262   Hs. 17538   ESTs   2.54       112983   T23443   Hs. 7111   ESTs   2.54       128279   H08885       yl88b08.r1 Soares infant brain 1NIB Homo   2.54       106415   AA447994   Hs. 29188   ESTs   2.53       116741   H03268   Hs. 181746   EST   2.53       103148   X66362   Hs. 2994   PCTAIRE protein kinase 3   2.53       132336   AA342422   Hs. 45073   ESTs   2.53       129484   R92488   Hs. 111989   ESTs   2.53       110169   H19696   Hs. 31612   ESTs; Moderately similar to CAGH4 [H.sap   2.53       116880   H68380   Hs. 144174   EST   2.53       133511   X04106   Hs. 74451   calpain; small polypeptide   2.53       126037   M85772   Hs. 6066   KIAA1112 protein   2.53       132678   AA599876   Hs. 5486   ESTs   2.53       128751   AA442274   Hs. 183176   ESTs   2.52       133664   X86693   Hs. 75445   hevin   2.52       126977   AA309665       EST180547 Jurkat T-cells V  Homo sapiens     2.52       120697   AA291522   Hs. 97250   EST   2.52       128571   AA416619   Hs. 101661   ESTs   2.52       104422   H86858   Hs. 132909   ESTs   2.52       122372   AA446008   Hs. 99044   EST   2.52       112154   R46769   Hs. 25388   ESTs   2.52       126900   R16034   Hs. 12701   ESTs; Highly similar to plasmolipin [H.s   2.51       115000   AA251342   Hs. 144584   ESTs   2.51       110632   H72344   Hs. 171635   ESTs   2.51       129154   N23673   Hs. 108969   mannosidase; alpha; class 2B; member 1   2.51       107440   W28069   Hs. 251993   ESTs; Weakly similar to similar to zinc   2.51       105694   AA287109   Hs. 37883   ESTs   2.51       106249   AA430388   Hs. 13144   ESTs; Weakly similar to ORF YGR038w [S.c   2.51       134462   U11037   Hs. 83620   sel-1 (suppressor of lin-12;  C.elegans )-   2.51       101800   M85276   Hs. 105806   granulysin   2.51       119884   W81606   Hs. 58662     Homo sapiens  mRNA; cDNA DKFZp564G212 (fr   2.51       110289   H29829   Hs. 31524   ESTs   2.51       125506   H54273   Hs. 154073   UDP-galactose transporter related   2.51       102954   X15393   Hs. 2813   motilin   2.51       127851   AI469331   Hs. 130497   ESTs; Weakly similar to CHLORIDE CONDUCT   2.5       126179   AI191445   Hs. 143855   ESTs; Highly similar to IROQUOIS-CLASS H   2.5       129443   W69967   Hs. 111497   ESTs; Moderately similar to neuronal pro   2.5       104480   N41486   Hs. 99654   protein-O-mannosyltransferase 1   2.5       115580   AA398695   Hs. 144339   Hu DNA seq frm clone 495O10 on chr 6q26-   2.5                   Prot L37A) pseudogene; last exon of gene for a novel prot smlr                   to worm E04F6.2; ESTs; STSs and GSSs       119595   W45031   Hs. 55878   EST   2.5       103336   X85785   Hs. 183   Duffy blood group   2.5       102792   U87964   Hs. 227576   GTP binding protein 1   2.49       129643   L27584   Hs. 250712   calcium channel; voltage-dependent; beta   2.49       134503   U34880   Hs. 84183   diptheria toxin resistance protein reqrd   2.49       117245   N20989   Hs. 42927   ESTs   2.49       126888   H78745   Hs. 1063   small nuclear ribonucleoprotein polypept   2.49       135313   D63484   Hs. 98508   KIAA0150 protein   2.49       121186   AA400156   Hs. 183294   ESTs   2.49       130651   X04445   Hs. 1734   inhibin; alpha   2.49       134218   AA227480   Hs. 80205   pim-2 oncogene   2.49       104008   AA334630       EST38874 Embryo, 9 week  Homo sapiens  cDN   2.49       129705   X78706   Hs. 12068   camitine acetyltransferase   2.49       127900   AI143912   Hs. 121824   ESTs   2.49       104609   R96417   Hs. 107795   ESTs   2.48       131628   U47292   Hs. 2979   trefoil factor 2 (spasmolytic protein 1)   2.48       132184   U51003   Hs. 419   distal-less homeo box 2   2.48       130450   U70735   Hs. 15591   COP9 subunit 6 (MOV34 homolog; 34 kD)   2.48       101679   M62628   Hs. 163271   Human alpha-1 Ig germline C-region membr   2.48       120858   AA350147   Hs. 96940   EST   2.48       101012   J04444   Hs. 697   cytochrome c-1   2.48       110453   H52133   Hs. 33026   ESTs; Weakly similar to similar to Enter   2.48       133771   M68891   Hs. 760   GATA-binding protein 2   2.48       102944   X14445   Hs. 37092   fibroblast grwth fctr 3 (murine mammary   2.48       113269   T65159   Hs. 85044   ESTs   2.48       107069   AA609045   Hs. 11759   ESTs; Weakly similar to !!!! ALU CLASS B   2.48       100476   HG1019-HT1019       Serine Kinase Psk-H1   2.47       106457   AA449718   Hs. 27801   zinc finger protein 278   2.47       105718   AA291629   Hs. 74335   heat shock 90 kD protein 1; beta   2.47       104925   AA058683   Hs. 5548     Homo sapiens  clone 23765 mRNA sequence   2.47       109913   H05527   Hs. 31588   ESTs   2.47       103412   X96698   Hs. 42957   methyltransferase-like 1   2.47       102326   U35246   Hs. 226025   vacuolar protein sorting 45A (yeast homo   2.47       116813   H49911   Hs. 93102   ESTs   2.47       123690   AA609566   Hs. 112723   EST   2.47       124714   R09486   Hs. 193118   ESTs   2.47       126154   AI004105   Hs. 14232   ESTs; Moderately similar to KIAA0563 pro   2.47       118880   N90168   Hs. 54593   EST   2.47       122274   AA437094   Hs. 184456   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.46       129600   N78980   Hs. 11567   ESTs; Moderately similar to unknown [H.s   2.46       121356   AA405437   Hs. 93581     Homo sapiens  mRNA; cDNA DKFZp586E171 (fr   2.46       109560   F01778   Hs. 8154   ESTs   2.46       123342   AA504336   Hs. 31659   thyroid hormone receptor-associated prot   2.46       128032   AI150084   Hs. 126678   ESTs   2.46       129101   H90310   Hs. 108665   ESTs; Weakly similar to CELL-CYCLE NUCLE   2.46       131185   M25753   Hs. 23960   cyclin B1   2.46       121451   AA411008   Hs. 98085   EST   2.46       104328   D81932       HUM424C5B Hu fetal brain (TFujiwara) H.s   2.46       126543   AA723810   Hs. 69517   ESTs; Highly similar to differentially e   2.45       123600   AA609106   Hs. 112644   ESTs   2.45       131020   AA411756   Hs. 20594   ESTs; Weakly similar to misato [D.melano   2.45       134191   W28902   Hs. 7979   KIAA0736 gene product   2.45       130446   X79510   Hs. 155693   protein tyrosine phosphatase; non-recept   2.45       131613   R88228   Hs. 29595   JM4 protein   2.45       118864   N89670   Hs. 42148   ESTs; Weakly similar to Su(P) [D.melanog   2.45       104232   AB002351   Hs. 10587   KIAA0353 protein   2.45       122604   AA453489   Hs. 99333   ESTs   2.45       120626   AA285064   Hs. 104485   EST   2.45       116655   F03866   Hs. 68090   ESTs   2.44       116267   AA485080   Hs. 256539   ESTs   2.44       114944   AA243172   Hs. 87619   TED protein   2.44       127629   AA293279   Hs. 29173   ESTs   2.44       120350   AA211300   Hs. 104166   ESTs   2.44       103620   Z47087   Hs. 182643   transcription elongation factor B (SIII)   2.44       131420   Z11737   Hs. 2664   flavin containing monooxygenase 4   2.44       131312   AA399226   Hs. 25527   tight junction protein 3 (zona occludens   2.43       122812   AA461044   Hs. 142980   EST   2.43       135100   AA398926   Hs. 251108     Homo sapiens  mRNA; chromosome 1 specific   2.43       113464   T86931   Hs. 16295   ESTs   2.43       100045   M11507       AFFX control: transferrin receptor   2.43       128975   AA092129   Hs. 107538   ESTs; Moderately similar to/prediction   2.43       103688   AA011479   Hs. 154701   ESTs   2.43       127331   F20186       HSPD05873 HM3  Homo sapiens  cDNA clone 05   2.43       107337   T97111   Hs. 191235   ESTs; Weakly similar to Ydr324cp [S.cere   2.43       122171   AA435750   Hs. 98830   EST   2.43       107601   AA004636   Hs. 50223   ESTs   2.43       119800   W73523   Hs. 58314   ESTs   2.43       104886   AA053348   Hs. 144626   growth differentiation factor 11   2.42       122899   AA469960   Hs. 178420   ESTs; Highly similar to WASP interacting   2.42       125933   AI308037   Hs. 84120   ESTs; Weakly similar to nucleoporin p62   2.42       121664   AA417291   Hs. 97978   ESTs   2.42       125450   AA377194   Hs. 238909   ESTs; Weakly similar to POLYPOSIS LOCUS   2.42       114611   AA081374   Hs. 108110   DKFZP547E2110 protein   2.42       111595   R11492   Hs. 191225   ESTs   2.42       111671   R19368   Hs. 229084   EST   2.42       110687   H93005   Hs. 177311   ESTs   2.42       103019   X53414   Hs. 144567   alanine-glyoxylate aminotransferase (oxa   2.42       119076   R36634   Hs. 235534   ESTs   2.42       130589   AA234308   Hs. 16441   DKFZP434H204 protein   2.42       125975   AA495891   Hs. 152290   ESTs; Highly similar to PACAP type-3/VIP   2.42       106380   AA446188   Hs. 16614   ESTs   2.41       121965   AA429652   Hs. 104901   EST   2.41       121604   AA416788   Hs. 98259   EST   2.41       100885   HG4490-HT4876       Proline-Rich Protein Prb4, Allele   2.41       117807   N48701   Hs. 46523   EST   2.41       119840   W79525   Hs. 58586   ESTs   2.41       102458   U48861   Hs. 54397   cholinergic receptor, nicotinic; beta po   2.41       116152   AA460920   Hs. 215683   ESTs; Moderately similar to !!!! ALU SUB   2.41       126741   AA522512   Hs. 29759     Homo sapiens  mRNA; cDNA DKFZp586L2123 (f   2.41       103381   X92715   Hs. 3057   zinc finger protein 74 (Cos52)   2.41       124837   R55630   Hs. 233602   KIAA0596 protein   2.41       129322   AA437153   Hs. 110407   ESTs; Weakly similar to coded for by C.   2.4       129291   AA281930   Hs. 110099   core-binding factor; runt domain; alpha   2.4       124789   R43803   Hs. 78110   ESTs; Weakly similar to F17A9.2 [C.elega   2.4       133253   Y00970   Hs. 183088   acrosin   2.4       118990   N94447   Hs. 55047   EST   2.4       134897   R71427   Hs. 9081   phenylalanyl-tRNA synthetase beta-subuni   2.4       116572   D45654   Hs. 65582   DKFZP586C1324 protein   2.4       104294   D14539   Hs. 234774   myeloid/lymphoid or mixed-lineage leukem   2.4       118764   N74440   Hs. 205264   ESTs   2.4       117437   N27645       yw5e3.s1 Weizmann Olfactory Epithelium H   2.4                   3′ similar to contains L1.t3 L1 repetit       111651   R16733   Hs. 20499   ESTs   2.39       109583   F02322   Hs. 26135   ESTs   2.39       125969   R94247   Hs. 193879   ESTs   2.39       130647   AA457216   Hs. 214190   interleukin enhancer binding factor 1   2.39       113708   T97487   Hs. 18065   ESTs   2.39       133469   L03785   Hs. 170482   myosin; light polypeptide 5; regulatory   2.39       118266   N62837   Hs. 48647   immunoglobulin-like transcript 7   2.39       121656   AA417248   Hs. 98212   ESTs   2.39       126530   AI422841   Hs. 180086   ESTs   2.39       123708   AA609648   Hs. 207767   EST   2.39       107875   AA025308   Hs. 61182   ESTs   2.39       111711   R22891   Hs. 7093   ESTs   2.39       131405   U79255   Hs. 26468   amyloid beta (A4) precursor protein-bind   2.39       127454   AA502957   Hs. 153590   ESTs   2.39       132341   AA448419   Hs. 45209   ESTs   2.38       133673   D87673   Hs. 75486   heat shock transcription factor 4   2.38       113213   T58607       ya94a02.s1 Stratagene placenta (#937225)   2.38       106230   AA429356   Hs. 12047   ESTs   2.38       116692   F09261   Hs. 66103   ESTs   2.38       126197   AA172284   Hs. 103657   ESTs; Weakly similar to CH-TOG PROTEIN [   2.38       115966   AA446866   Hs. 71371   ESTs   2.38       132636   U65785   Hs. 5417   oxygen regulated protein (150 kD)   2.38       109965   H09077   Hs. 30895   EST   2.38       130203   L14754   Hs. 1521   immunoglobulin mu binding protein 2   2.38       131332   R50487   Hs. 25717   ESTs   2.38       119105   R42357   Hs. 91453   ESTs   2.37       129253   W69316   Hs. 109778   ESTs; Weakly similar to similar to beta-   2.37       113602   T92558   Hs. 17036   ESTs   2.37       118102   N55272   Hs. 145798   ESTs   2.37       100734   HG3432-HT3620       Fibroblast Growth Factor Receptor K-Sam, Alt. Splice 3, K-Sam lii   2.37       111533   R08548   Hs. 251651   EST   2.37       130813   U12259   Hs. 198   paired box gene 3 (Waardenburg syndrome   2.37       119180   R80413   Hs. 92520   ESTs   2.37       109335   AA211443   Hs. 86492   ESTs   2.37       107386   U97698   Hs. 159593   mucin 6; gastric   2.36       122486   AA448328   Hs. 115527   ESTs   2.36       112997   T23548   Hs. 167467   ESTs   2.36       109674   F09051   Hs. 21837   ESTs; Weakly similar to KIAA0927 protein   2.36       128868   AA423827   Hs. 106730   hypothetical protein   2.36       127027   R17261       yg12g07.r1 Soares infant brain 1NIB H.sa   2.36       123099   AA485931   Hs. 79   aminoacylase 1   2.36       115716   AA416767   Hs. 43498   ESTs; Weakly similar to ORF YKL201c [S.c   2.36       130830   D86982   Hs. 20060   KIAA0229 protein   2.36       109051   AA159920   Hs. 72322   ESTs   2.36       130181   R39552   Hs. 151608     Homo sapiens  clone 23622 mRNA sequence   2.36       131114   R46233   Hs. 23107   ESTs   2.36       123589   AA609047   Hs. 188922   ESTs   2.36       130872   U03891       phorbolin (similar to apolipoprotein B m   2.36       131962   H78550   Hs. 2780   jun D proto-oncogene   2.36       130502   M55067   Hs. 1583   neutrophil cytosolic factor 1 (47 kD; chr   2.36       121785   AA423883   Hs. 142442   ESTs   2.35       125405   T97171   Hs. 121570   ESTs   2.35       103682   AA000993       ESTs   2.35       125649   T77395   Hs. 194816   stomatin-like protein 1   2.35       115452   AA285019   Hs. 55263   ESTs; Highly similar to mitochondrial di   2.35       129338   T56800   Hs. 47274     Homo sapiens  mRNA; cDNA DKFZp564B176 (fr   2.35       106105   AA421268   Hs. 149443   putative tumor suppressor   2.35       134770   R72079   Hs. 89575   CD79B antigen (immunoglobulin-associated   2.35       119422   T99496   Hs. 229598   EST   2.35       109869   H02849   Hs. 30345   EST   2.35       134314   AA263032   Hs. 81634   ATP synthase; H+ transporting; mitochond   2.35       114989   AA251097   Hs. 189119   ESTs   2.35       122619   AA453755   Hs. 191515   ESTs   2.35       133129   AA428580   Hs. 65551   ESTs   2.35       128465   AA416762   Hs. 100221   nuclear receptor subfamily 1; group H; m   2.35       115636   AA402715   Hs. 58389   ESTs   2.35       130836   J05068   Hs. 2012   transcobalamin I (vitamin B12 binding pr   2.34       132385   Y10256   Hs. 47007   serine/threonine protein-kinase   2.34       107776   AA018820   Hs. 221147   ESTs   2.34       109791   F10669   Hs. 13228   DRE-antagonist modulator; calsenilin   2.34       124409   N33212   Hs. 107197   ESTs   2.34       131068   AA397916   Hs. 22595   ESTs   2.34       121079   AA398719   Hs. 14169   ESTs; Weakly similar to CREB-binding pro   2.34       124662   N94340   Hs. 171835   ESTs; Weakly smlr to PUT PRE-MRNA SPLICI   2.34       133820   M13686   Hs. 177582   surfactant; pulmonary-associated protein   2.34       129424   M55593   Hs. 111301   matrix metalloproteinase2 (gelatinase A   2.34       109066   AA161377   Hs. 72404   EST   2.34       100339   D63485   Hs. 181359   KIAA0151 gene product   2.34       100809   HG3991-HT4261       Cpg-Enriched Dna, Clone E18   2.34       120844   AA349417   Hs. 96917   ESTs   2.33       124927   R96146   Hs. 221459   ESTs   2.33       109779   F10527   Hs. 3353     Homo sapiens  clone 24940 mRNA sequence   2.33       101171   L16842   Hs. 119251   ubiquinol-cytochrome c reductase core pr   2.33       110805   N26904   Hs. 24048   ESTs; Weakly similar to FK506/rapamycin-   2.33       125440   AI090982   Hs. 31895   ESTs   2.33       133159   AC000061   Hs. 663   cystic fibrosis transmemb conductance re   2.33       101829   M91368   Hs. 129763   solute carrier family 8 (sodium/calcium   2.33       126492   AA778565   Hs. 142505   ESTs   2.33       102774   U83303   Hs. 164021   small inducible cytokine subfamily B (CX   2.33       130480   N50809   Hs. 15760   ESTs; Weakly similar to similar to Yeast   2.33       126878   AI424759   Hs. 238928   ESTs   2.33       117338   N23889   Hs. 43466   ESTs   2.32       118662   N70877   Hs. 13055   ESTs   2.32       130354   AA416685   Hs. 155001   UNC13 ( C. elegans )-like   2.32       106760   AA477330   Hs. 12293   ESTs   2.32       124294   H90573   Hs. 102298   EST   2.32       119428   W02129   Hs. 55242   EST   2.32       132629   Z40942   Hs. 5383   ESTs   2.32       127998   AA854161   Hs. 143585   ESTs   2.32       132728   AA293334   Hs. 5566   ESTs; Highly similar to RAS-RELATED PROT   2.32       120292   AA189116   Hs. 96168   ESTs   2.32       107598   AA004528   Hs. 169444   ESTs   2.32       128164   AI478174   Hs. 144846   ESTs   2.32       105753   AA299789   Hs. 15277   ESTs   2.31       131256   AA262340   Hs. 24907   coronin; actin-binding protein: 2B   2.31       110891   N38863   Hs. 234392   platelet-activating factor acetylhydrola   2.31       116767   H13689   Hs. 92530   ESTs   2.31       100545   HG2147-HT2217       Mucin 3, Intestinal (Gb: M55405)   2.31       125264   W88995   Hs. 167641   ESTs; Weakly similar to C15H9.5 [C.elega   2.31       118387   N64579       yz51d11.s1 Morton Fetal Cochlea H.sapien   2.31       104335   D83847   Hs. 183864   elastase 3B   2.31       107464   W42944   Hs. 171939   ESTs   2.31       112304   R54798   Hs. 26239   ESTs   2.31       134313   AA136100   Hs. 6673   trinucleotide repeat containing 15   2.31       116322   AA490900   Hs. 58643   ESTs; Highly similar to JAK3B [ H. sapiens     2.31       111275   N70970   Hs. 35006   ESTs   2.31       100109   AJ000480   Hs. 143513   phosphoprotein regulated by mitogenic pa   2.31       109338   AA211717   Hs. 86507   ESTs   2.31       134432   AA053022   Hs. 8312   ESTs   2.31       129649   AD000092   Hs. 182628     Homo sapiens  DNA from chr 19p13.2 cosmid   2.31                   EKLF; GCDH; CRTC; and RAD23A genes; gen       122623   AA453990   Hs. 99248   ESTs   2.31       112070   R43976   Hs. 236310   EST   2.31       127683   AA668123   Hs. 134170   ESTs   2.31       104920   AA057620   Hs. 30807   ESTs; Highly similar to dJ186O1.1 [H.sap   2.31       106064   AA417373   Hs. 15898   ESTs   2.31       106782   AA478487       ESTs   2.31       126709   AA028159   Hs. 47234   ESTs   2.3       105129   AA158386   Hs. 186476   ESTs   2.3       105719   AA291644   Hs. 36793   ESTs   2.3       121698   AA418399   Hs. 10351   KIAA0308 protein   2.3       119069   R27619   Hs. 231046   EST   2.3       130388   U72515   Hs. 189583   putative protein similar to nessy (Droso   2.3       103444   X98801   Hs. 74617   dynactin 1 (p150; Glued (Drosophila) hom   2.3       114604   AA076128       zm18g4.s1 Stratagene pancreas (#93728) H   2.3                   3′ similar to SW: RS1A_HUMAN P3927 4S RI   2.3       103878   AA227635   Hs. 202588   ESTs   2.3       105828   AA398276   Hs. 11962   ESTs   2.3       119778   W72920   Hs. 58244   ESTs   2.3       120401   AA234309   Hs. 193011   ESTs   2.3       116290   AA488691   Hs. 57969   phenylalanine-tRNA synthetase   2.3       130479   R44163   Hs. 12457     Homo sapiens  clone 23770 mRNA sequence   2.3       104253   AF002672   Hs. 152944   loss of heterozygosity; 11; chromosomal   2.29       132615   H66367   Hs. 53358   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.29       121954   AA429598   Hs. 98587   ESTs   2.29       101336   L49169   Hs. 75678   FBJ murine osteosarcoma viral oncogene h   2.29       127247   AA313802   Hs. 6289   growth factor receptor-bound protein 2   2.29       117300   N22565   Hs. 43212   ESTs   2.29       122229   AA436198   Hs. 103902   ESTs   2.29       125106   T95766   Hs. 189760   ESTs   2.29       128083   R16100   Hs. 166476   ESTs   2.29       131279   AA089853   Hs. 25197   STIP1 homology and U-Box containing prot   2.29       133838   M97796   Hs. 180919   inhibitor of DNA binding 2; dominant neg   2.29       111837   R36447   Hs. 24453   ESTs   2.29       111435   R01620   Hs. 19198   ESTs   2.29       123613   AA609158   Hs. 112656   EST   2.29       133560   AA256365   Hs. 7486   protein expressed in thyroid   2.29       122896   AA469952   Hs. 97899   ESTs; Weakly similar to dal2; len: 343; C   2.29       113378   T80627   Hs. 14757   ESTs   2.29       127174   AA293204   Hs. 139352   ESTs   2.29       120153   Z39582   Hs. 65777   EST   2.29       112741   R93080   Hs. 35035   ESTs   2.28       132152   AA044784   Hs. 4105     Homo sapiens  mRNA; cDNA DKFZp586A0618 (f   2.28       109790   F10665   Hs. 25031   ESTs   2.28       113776   W04657   Hs. 24248   ESTs   2.28       102934   X13451       Hu mRNA for lymphocyte lineage-rstrcted   2.28       126188   AA322034       EST24690 Cerebellum II  Homo sapiens  cDNA   2.28       126363   N94706       Human Chromosome 16 BAC clone CIT987SK-A   2.28       101427   M19508       Human myeloperoxidase gene, exons 1-4   2.28       132616   AA386264   Hs. 5337   isocitrate dehydrogenase 2 (NADP+); mito   2.28       105537   AA258813   Hs. 27160   ESTs   2.28       126527   AA548559   Hs. 103853   ESTs   2.28       115359   AA281936   Hs. 88914   ESTs   2.28       108474   AA079667       zm93d1.s1 Stratagene ovarian cncr (#9372   2.28       120685   AA291066   Hs. 105099   ESTs   2.28       126171   AA704771   Hs. 191942   ESTs   2.28       112858   T02963   Hs. 4454   ESTs   2.28       121817   AA424826   Hs. 98475   EST   2.28       107895   AA026150   Hs. 61384   ESTs   2.28       131161   Z38223   Hs. 23735   potassium voltage-gated channel; subfami   2.28       135173   M72885   Hs. 95910   Human G0S2 protein gene; complete cds   2.27       103182   X69819   Hs. 99995   intercellular adhesion molecule 3   2.27       113889   W72720   Hs. 194347   ESTs   2.27       128984   AA319615   Hs. 238030   secretory carrier membrane protein 2   2.27       101531   M29877   Hs. 576   fucosidase; alpha-L-1; tissue   2.27       115916   AA436889   Hs. 91910   ESTs   2.27       129892   H96850   Hs. 89674   dolichyl-diphosphooligosaccharide-protei   2.27       103035   X54871   Hs. 77690   RAB5B; member RAS oncogene family   2.27       126479   T78141       ESTs   2.27       125778   R71976   Hs. 161791   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.27       108132   AA053586   Hs. 63048   ESTs   2.27       111017   N53965   Hs. 256327   ESTs   2.27       127165   AA359719   Hs. 127121   ESTs   2.27       126446   AI421309   Hs. 118926   DKFZP586K0919 protein   2.26       107864   AA025061   Hs. 61246   ESTs   2.26       122277   AA437133   Hs. 98936   ESTs   2.26       115604   AA400378   Hs. 49391   ESTs   2.26       105061   AA134824   Hs. 4865   ESTs   2.26       118549   N68163   Hs. 49455   EST   2.26       110509   H56493   Hs. 61960   ESTs; Moderately similar to HYPOTHETICAL   2.26       114088   Z38280   Hs. 26971   Human Chromosome 16 BAC clone CIT987SK-2   2.26       103225   X74837   Hs. 2750   mannosidase; alpha; class 1A; member 1   2.26       125842   AA746654   Hs. 5181   proliferation-associated 2G4; 38 kD   2.26       104538   R25069   Hs. 175681   ESTs   2.26       130304   U09368   Hs. 154205   zinc finger protein 140 (clone pHZ-39)   2.26       120680   AA290743   Hs. 97242   ESTs   2.26       124062   H00440   Hs. 144524   ESTs; Weakly similar to signal transduce   2.26       103289   X80915   Hs. 1573   growth differentiation factor 5 (cartila   2.26       109286   AA197273   Hs. 191324   ESTs   2.26       128555   U62739   Hs. 101408   branched chain aminotransferase 2; mitoc   2.26       129439   AA171694   Hs. 111461   ceruloplasmin (ferroxidase)   2.26       109221   AA192755   Hs. 85840   ESTs; Weakly similar to stac [ H. sapiens ]   2.26       109906   H05084   Hs. 28077   ESTs; Highly similar to GDP-mannose pyro   2.26       130540   U35234   Hs. 159534   protein tyrosine phosphatase; receptor t   2.26       122870   AA405158   Hs. 192861   Spi-B transcription factor (Spi-1/PU.1 r   2.26       120219   Z41124   Hs. 66045   EST   2.26       128021   AI001136   Hs. 78223   N-acylaminoacyl-peptide hydrolase   2.26       121732   AA421047   Hs. 98330   ESTs   2.26       107817   AA020781   Hs. 60847   ESTs   2.25       101069   L02648   Hs. 84232   transcobalamin II; macrocytic anemia   2.25       103065   X58399   Hs. 81221   Human L2-9 transcript of unrearranged im   2.25       118019   N52585   Hs. 47517   ESTs   2.25       122220   AA436011   Hs. 98187   ESTs   2.25       109161   AA179392   Hs. 73601   EST   2.25       128699   K03207   Hs. 103972   proline-rich protein BstNI subfamily 4   2.25       101914   S71824   Hs. 167988   neural cell adhesion molecule 1   2.25       102697   U74667   Hs. 6364   Tat interactive protein (60 kD)   2.25       119939   AA86753   Hs. 82407   ESTs   2.25       127793   AI298835   Hs. 30445   ESTs; Weakly similar to transcription re   2.25       104450   L77564   Hs. 103978   serine/threonine kinase 22B (spermiogene   2.25       133096   AA136042   Hs. 131053   ESTs   2.25       115416   AA283893   Hs. 203866   ESTs   2.25       117058   H90322   Hs. 41387   EST   2.25       115598   AA400129   Hs. 65735   ESTs   2.25       121267   AA401397   Hs. 165296   ESTs; Highly similar to kallikrein-like   2.25       104778   AA026397   Hs. 11039     Homo sapiens  clone 24804 mRNA sequence   2.25       110926   N48252   Hs. 135287   ESTs   2.24       102795   U88667   Hs. 198396   ATP-binding cassette; sub-family A (ABC1   2.24       118643   N70324   Hs. 49840   ESTs   2.24       103304   X82240   Hs. 2484   T-cell leukemia/lymphoma 1A   2.24       134814   Z48475   Hs. 89771   glucokinase (hexokinase 4) regulatory pr   2.24       125912   AA171719   Hs. 5233   eukaryotic translation initiation factor   2.24       134365   R32377   Hs. 82240   syntaxin 3A   2.24       117224   N20300   Hs. 218707   ESTs   2.24       107169   AA621601   Hs. 184446   ESTs; Weakly similar to small GTP-bindin   2.24       133948   M59916   Hs. 77813   sphingomyelin phosphodiesterase 1; acid   2.24       101426   M19483   Hs. 25   ATP synthase; H+ transporting; mitochond   2.24       119922   W86196   Hs. 177384   ESTs   2.24       123361   AA504810   Hs. 139649   EST   2.24       123915   AA621298   Hs. 112967   ESTs   2.24       123540   AA608792   Hs. 112591   EST   2.24       124978   T40560   Hs. 221759   ESTs   2.24       102354   U38268       Human cytochrome b pseudogene, partial c   2.24       124198   H53099   Hs. 198271   NADH dehydrogenase (ubiquinone) 1 alpha   2.24       102160   U18235   Hs. 121561   ATP-binding cassette; sub-family A (ABC1   2.24       107520   X76091   Hs. 100007   regulatory factor X; 2 (influences HLA c   2.24       131589   U52100   Hs. 29191   epithelial membrane protein 2   2.24       126633   AA206993   Hs. 154145   guanine nucl binding protein (G protein)   2.23       130887   AA258379   Hs. 155986   angiotensin receptor-like 2   2.23       119894   W84670   Hs. 58518   EST   2.23       124544   N63837   Hs. 40500   similar to  S. cerevisiae  RER1   2.23       103104   X61587   Hs. 75082   ras homolog gene family; member G (rho G   2.23       110119   H17306   Hs. 177229   ESTs   2.23       131411   AA464043   Hs. 26506   ESTs; Weakly similar to NY-REN-45 antige   2.23       102346   U37359   Hs. 227297   meiotic recombination (S. cerevisiae) 11   2.23       106003   AA411167   Hs. 8734   ESTs; Moderately similar to !!!! ALU CLA   2.23       122564   AA452251   Hs. 98669   ESTs   2.23       133688   U42031   Hs. 7557   FK506-binding protein 5   2.23       132096   AA131410   Hs. 3964     Homo sapiens  clone 24877 mRNA sequence   2.23       110038   H11746   Hs. 31097   ESTs   2.23       123788   AA620293   Hs. 112853   ESTs   2.23       135070   X99350   Hs. 93974   forkhead box J1   2.23       104908   AA055841   Hs. 154396   ESTs   2.22       128674   AA025001   Hs. 169452   ESTs   2.22       100810   HG3992-HT4262       Cpg-Enriched Dna, Clone E35   2.22       120065   W93579   Hs. 59478   EST   2.22       122775   AA459692   Hs. 112143   ESTs   2.22       125443   H71482   Hs. 177592   tibosomal protein; large; P1   2.22       118617   N69666   Hs. 183413   ESTs; Moderately similar to !!!! ALU SUB   2.22       128001   AI167814   Hs. 166664   ESTs   2.22       128160   AI279080   Hs. 149971   ESTs; Moderately similar to !!!! ALU CLA   2.22       106608   AA458644   Hs. 27115   ESTs   2.22       103485   Y08409   Hs. 248415   thyroid hormone responsive SPOT14 (rat)   2.22       135008   AA173423   Hs. 92918   ESTs; Weakly similar to R07G3.8 [C.elega   2.22       110122   H17333   Hs. 159837   EST   2.22       128397   AI393421   Hs. 14032   ESTs   2.22       110231   H24359   Hs. 28733   ESTs   2.22       123188   AA489092   Hs. 177726   ESTs   2.22       131903   AA481723   Hs. 3436   deleted in oral cancer (mouse; homolog)   2.22       122649   AA454616   Hs. 90336   ATPase; H+ transporting; lysosomal (vacu   2.22       133090   AA448228   Hs. 6468   ESTs   2.22       108002   AA037664   Hs. 55067   ESTs; Weakly similar to T07F12.1 gene pr   2.22       133120   X64559   Hs. 65424   tetranectin (plasminogen-binding protein   2.21       114263   Z40073   Hs. 6045   ESTs   2.21       125518   R20148   Hs. 193851   ESTs   2.21       128613   U78551   Hs. 102482     Homo sapiens  gallbladder mucin MUC5B mRN   2.21       102773   U83192   Hs. 23731   discs; large (Drosophila) homolog 4   2.21       119526   W38049       Accession not listed in Genbank   2.21       126844   AA299325       EST11903 Uterus tumor I  Homo sapiens  cDN   2.21       105860   AA399251   Hs. 180933   ESTs; Weakly similar to methyl-CpG bindi   2.21       126957   AA733145   Hs. 194560   ESTs   2.21       108959   AA150107   Hs. 81810   ESTs   2.2       131663   AA423926   Hs. 30318   ESTs   2.2       127468   H02941   Hs. 8888   ESTs   2.2       104483   N42776   Hs. 146233   EST   2.2       123848   AA620773   Hs. 221996   ESTs   2.2       101623   M55905   Hs. 75342   malic enzyme 2; NAD(+)-dependent; mitoch   2.2       120872   AA357993   Hs. 96996   ESTs   2.2       135033   AA173241   Hs. 93454   ESTs   2.2       122286   AA437259   Hs. 104944   EST   2.2       114862   AA235174   Hs. 50250   ESTs   2.2       100255   D38047   Hs. 78466   proteasome (prosome; macropain) 26S subu   2.2       103063   X58234   Hs. 123178   translocase of inner mitochondrial membr   2.2       132777   R56898   Hs. 56663   ESTs   2.2       133082   AA457129   Hs. 6455   RuvB ( E. coli  homolog)-like 2   2.2       127529   AA558980   Hs. 191750   ESTs   2.2       114602   AA075642   Hs. 103594   deleted in malignant brain tumors 1   2.2       120722   AA293435   Hs. 97277   ESTs   2.2       102675   U72512       Human B-cell receptor associated protein   2.2       128551   H09058   Hs. 237323   N-acetylglucosamine-phosphate mutase; DK   2.2       112020   R43001   Hs. 22298   EST   2.2       123625   AA609216   Hs. 112666   EST   2.2       120315   AA194266   Hs. 178393   ESTs   2.2       122081   AA431992   Hs. 104920   ESTs   2.19       101798   M85220       Accession not listed in Genbank   2.19       111501   R07444   Hs. 163118   ESTs   2.19       132832   D63482   Hs. 57734   KIAA0148 gene product   2.19       100544   HG2147-HT2217       Mucin 3, Intestinal (Gb: M55405)   2.19       106835   AA482077   Hs. 33713   ESTs; Weakly similar to hypothetical pro   2.19       132934   AA076145   Hs. 61053   ESTs   2.19       108762   AA127515   Hs. 71787   ESTs; Highly similar to 30S ribosomal pr   2.19       120164   Z39733   Hs. 158159   FAT tumor suppressor (Drosophila) homolo   2.19       135395   L08096   Hs. 99899   tumor necrosis factor (ligand) superfami   2.19       101717   M69013   Hs. 1686   guanine nucleotide binding protein (G pr   2.19       121172   AA400013   Hs. 97750   EST   2.18       114861   AA235123   Hs. 40719   ESTs   2.18       120851   AA349662   Hs. 174248   ESTs   2.18       121083   AA398736   Hs. 97653   EST   2.18       107171   AA621624   Hs. 28088     Homo sapiens  clone 24515 mRNA sequence   2.18       128754   D31446   Hs. 10488   Breakpoint cluster region protein; uteri   2.18       100149   D13897   Hs. 169249   peptide YY   2.18       132405   AA323787   Hs. 4770   KIAA1068 protein   2.18       114666   AA112274       zm27g6.s1 Stratagene pancreas (#93728) H   2.18                   element; contains element LTR8 repetitiv       127008   AA223879       zr10g05.r1 Stratagene NT2 neuronal precu   2.18       110373   H42896   Hs. 29438   ESTs   2.18       119354   T66942   Hs. 100651   golgi SNAP receptor complex member 2   2.18       130115   M31627   Hs. 149923   X-box binding protein 1   2.18       130514   AA161085   Hs. 15871   ESTs; Weakly similar to acid phosphatase   2.18       128848   H08077   Hs. 217179   ESTs; Weakly similar to T27A1.5 [C.elega   2.18       110161   H19312   Hs. 28096   ESTs   2.18       132367   X82224   Hs. 46634   cysteine conjugate-beta lyase; cytoplasm   2.18       125882   H45538   Hs. 101448   metastasis associated 1   2.17       113837   W57698   Hs. 8888   ESTs   2.17       106376   AA444004   Hs. 6084   ESTs   2.17       113755   T99075   Hs. 18570   ESTs   2.17       107525   X91817   Hs. 102866   transketolase-like 1   2.17       119207   R93186   Hs. 84298   CD74 antigen (invar polypept of maj hist   2.17       131862   AA236365       3-phosphoglycerate dehydrogenase   2.17       115514   AA297739   Hs. 55609   ESTs; Weakly similar to ISOLEUCYL-TRNA S   2.17       112290   R53940   Hs. 26016   ESTs   2.17       126136   H83353       yv82f02.r1 Soares melanocyte 2NbHM Homo   2.17       121574   AA412712   Hs. 119325   Huntingtin-interacting protein A   2.17       118530   N67900   Hs. 118446   ESTs   2.16       132327   AA203285   Hs. 44892   ESTs; Weakly similar to dJ733D15.1 [H.sa   2.16       100564   HG2239-HT2324       Potassium Channel Protein (Gb: Z11585)   2.16       129376   AA022622   Hs. 13543   ESTs; Weakly similar to hypothetical pro   2.16       135317   X86012   Hs. 98602   Human DNA sequence from intron 22 of the   2.16                   9.5 kb repeated region; int22h-1; involv       114973   AA250845   Hs. 87762   ESTs   2.16       107559   AA001504   Hs. 59860   ESTs   2.16       111014   N53787   Hs. 191117   ESTs   2.16       101250   L34060   Hs. 79133   cadherin 8   2.16       110697   H93721   Hs. 20798   ESTs   2.16       126843   AA450166   Hs. 22641   ESTs; Moderately similar to predicted pr   2.16       108272   AA063616   Hs. 43773   ESTs   2.16       125012   T66935   Hs. 104859   ESTs   2.16       111639   R16101   Hs. 140834   EST   2.15       123157   AA488443   Hs. 100426   DKFZP564A063 protein   2.15       102315   U34252   Hs. 2533   aldehyde dehydrogenase 9 (gamma-aminobut   2.15       131897   AA287623   Hs. 3426   GTPase; human homolog of  E. coli  essenti   2.15       121528   AA412253   Hs. 238909   ESTs; Weakly similar to POLYPOSIS LOCUS   2.15       122806   AA460707   Hs. 106397   ESTs   2.15       125727   H00958   Hs. 181641   ESTs   2.15       133279   AA069571   Hs. 6957     Homo sapiens  clone 24616 mRNA sequence   2.15       103219   X74570   Hs. 75268   sialyltransferase 4C (beta-galactosidase   2.15       120881   AA362144   Hs. 104601   EST   2.15       134060   D42039   Hs. 78871   KIAA0081 protein   2.15       106598   AA457140   Hs. 11411   DKFZP566O084 protein   2.15       125576   R66208       yi30h03.r1 Soares placenta Nb2HP H sapie   2.15                   contains Alu repetitive element; contain       126727   AA037230   Hs. 135084   cystatin C (amyloid angiopathy and cereb   2.15       101490   M25629   Hs. 123107   kallikrein 1; renal/pancreas/salivary   2.15       129708   AA417181   Hs. 120858   ESTs   2.14       100627   HG2702-HT2798       Serine/Threonine Kinase (Gb: Z25424)   2.14       121703   AA418671   Hs. 104807   ESTs   2.14       106809   AA479704   Hs. 220324   Humn DNA seq frm clone 283E3 on chr 1p36   2.14                   Female Reproductive tract MIFR1; -2; MM       129525   F03873   Hs. 112306     Homo sapiens  clone 24955 mRNA sequence;   2.14       100478   HG1067-HT1067       Mucin (Gb: M22406)   2.14       118593   N69020   Hs. 207689   EST   2.14       114047   W94427   Hs. 3807   ESTs; Weakly similar to PHOSPHOLEMMAN PR   2.14       128823   AA478207   Hs. 10632   ESTs; Moderately similar to sex-determin   2.14       100534   HG1980-HT2023       Tubulin, Beta 2   2.14       105757   AA321146   Hs. 30596   ESTs   2.14       109617   F03192   Hs. 26789   ESTs; Weakly similar to dJ162H14.1 [H.sa   2.14       121547   AA412448   Hs. 104777   ESTs   2.14       119420   T98291   Hs. 102484   glutathione S-transferaseA3   2.14       120274   AA177051       nc02a02.s1 NCI_CGAP_Pr3  Homo sapiens  cDN   2.14                   repetitive element;contains element LTR       132933   AA598702   Hs. 6101   bone morphogenetic protein 6   2.14       133405   X07881   Hs. 73031   proline-rich protein BstNI subfamily 3   2.14       119811   W73922   Hs. 49047   ESTs   2.14       134536   AA457735   Hs. 850   IMP (inosine monophosphate) dehydrogenas   2.14       105125   AA157799   Hs. 6980   aldo-keto reductase family 7; member A2   2.14       101398   M15881   Hs. 1137   uromodulin (uromucoid;Tamm-Horsfall gly   2.14       132751   AA397901   Hs. 55993   ESTs   2.13       115777   AA424142   Hs. 39384   putative secreted ligand homologous to f   2.13       123193   AA489228   Hs. 136956   ESTs   2.13       116875   H67749   Hs. 161022   EST   2.13       107271   D60607   Hs. 34931   EST   2.13       134551   R44839   Hs. 8526   i-beta-1; 3-N-acetylglucosaminyltransfera   2.13       113413   T83739   Hs. 186512   ESTs   2.13       120522   AA258843   Hs. 258748   ESTs   2.13       119965   W87738   Hs. 59039   EST   2.13       131283   AA101601   Hs. 183986   herpesvirus entry mediator B (poliovirus   2.13       107347   U43628   Hs. 102598   mucosal vascular addressin cell adhesion   2.13       116490   C14265   Hs. 66450   ESTs   2.13       100563   HG2239-HT2324       Potassium Channel Protein (Gb: Z11585)   2.13       110441   H50302   Hs. 19845   ESTs; Highly similar to protein phosphat   2.13       101035   J05158   Hs. 73858   carboxypeptidase N; polypeptide 2; 83 kD   2.13       132500   AA047297   Hs. 50107   ESTs; Moderately similar to CDO [H.sapie   2.13       129807   L34820   Hs. 5299   aldehyde dehydrogenase 5 family; member   2.13       106250   AA430466   Hs. 28890   ESTs   2.13       113569   T91086   Hs. 162070   EST   2.13       122911   AA470087   Hs. 239726   ESTs   2.13       107452   W28988   Hs. 250746   ESTs   2.12       111824   R35661   Hs. 25006   EST   2.12       132831   U53442   Hs. 57732   mitogen-activated protein kinase 11   2.12       110244   H26742   Hs. 25367   ESTs; Weakly similar to ALR [ H. sapiens ]   2.12       128918   H85347   Hs. 107164   spectrin; beta; non-erythrocytic 1   2.12       133728   M10901   Hs. 75772   nuclear receptor subfamily 3; group C; m   2.12       122476   AA448211   Hs. 99164   ESTs   2.12       132004   L37360   Hs. 37054   ephrin-A3   2.12       113971   W86760   Hs. 220682   ESTs   2.12       103386   X92972   Hs. 80324   protein phosphatase 6; catalytic subunit   2.12       131120   AA443676   Hs. 23133   ESTs; Weakly similar to alcohol sulfotra   2.12       102186   U20285       G protein pathway suppressor 1   2.12       103694   AA018541   Hs. 60580   zinc finger protein   2.12       111995   R42333   Hs. 20893   ESTs   2.12       124436   N39596   Hs. 182584   ESTs   2.12       100306   D50495   Hs. 80598   transcription elongation factor A (SII);   2.12       103084   X59932   Hs. 77793   c-src tyrosine kinase   2.11       115092   AA255903   Hs. 80975   CD39-like 4   2.11       121579   AA416543   Hs. 111981   ESTs   2.11       127101   AI349351   Hs. 118944   ESTs   2.11       121195   AA400273   Hs. 97791   ESTs   2.11       112721   R91484   Hs. 30853   ESTs   2.11       113253   T64207   Hs. 55296   HLA-B associated transcript-1   2.11       120838   AA348887   Hs. 96907   ESTs   2.11       114122   Z38582   Hs. 12751   ESTs   2.11       112635   R82298   Hs. 29497   ESTs   2.11       103785   AA095600   Hs. 225647   ESTs   2.11       128260   AA331445       EST35277 Embryo, 8 week I  Homo sapiens  c   2.11       122987   AA479155   Hs. 103364   ESTs   2.11       110374   H42983   Hs. 227263   ESTs   2.11       116595   D60625   Hs. 177656   calmodulin 1 (phosphorylase kinase; delt   2.11       126117   H78617       yu26a08.r1 Soares fetal liver spleen 1NF   2.11       116610   D80448   Hs. 45177   ESTs   2.11       111430   R01248   Hs. 19165   ESTs   2.11       106700   AA463929   Hs. 28701   ESTs   2.11       120181   Z40121   Hs. 65870   ESTs; Weakly similar to Pro-Pol-dUTPase   2.1       132545   AA147218   Hs. 5105   ESTs   2.1       105005   AA115253   Hs. 28805   ESTs   2.1       126702   U54602   Hs. 2785   keratin 17   2.1       124096   H10060   Hs. 101687   EST   2.1       132720   Z69881   Hs. 5541   ATPase; Ca++ transporting; ubiquitous   2.1       121926   AA428559   Hs. 104895   ESTs   2.1       125734   AA157445   Hs. 227391   DKFZP547E1010 protein   2.1       122368   AA443963   Hs. 104964   EST   2.1       116910   H72014   Hs. 161031   ESTs; Weakly similar to SYNAPTOTAGMIN I   2.1       113171   T54613   Hs. 9761   EST   2.1       134629   U00951   Hs. 87150   Human clone A9A2BR11 (CAC)n/(GTG)n repea   2.1       105712   AA291293   Hs. 25219   ESTs   2.1       106931   AA495918   Hs. 26714   ESTs   2.1       114278   Z40424   Hs. 27728   ESTs   2.1       116615   D80666   Hs. 45203   ESTs   2.09       100189   D21089   Hs. 320   xeroderma pigmentosum; complementation g   2.09       119500   W37694   Hs. 55561   ESTs   2.09       129605   S72493   Hs. 115947   keratin 16 (focal non-epidermolytic palm   2.09       133912   X62744   Hs. 77522   major histocompatibility complex; class   2.09       129636   N34942   Hs. 11782   ESTs   2.09       106372   AA443941   Hs. 4992   tumor suppressing subtransferable candid   2.09       101885   M98539   Hs. 8272   prostaglandin D2 synthase (21 kD; brain)   2.09       132749   AA235989   Hs. 55967   short stature homeobox 2   2.09       135042   X91348   Hs. 93522   putative non-coding transcript (DiGeorge   2.09       109404   AA224594   Hs. 86941   ESTs   2.09       101333   L47738   Hs. 80313   p53 inducible protein   2.09       100114   D00596   Hs. 82962   thymidylate synthetase   2.09       130536   T17045   Hs. 159492   spastic ataxia of Charlevoix-Saguenay (s   2.09       125772   R83903   Hs. 78040   KDEL (Lys-Asp-Glu-Leu) endoplasmic retic   2.09       132192   AA247569   Hs. 4209   ESTs   2.09       124697   R06273   Hs. 186467   ESTs; Moderately similar to !!!! ALU SUB   2.09       127694   AI247780   Hs. 117036   ESTs   2.08       127895   AA772600   Hs. 187998   ESTs; Weakly similar to ATP-binding cass   2.08       121315   AA402883   Hs. 82269   progestagen-associated endometrial prote   2.08                   endometrial alpha-2-globulin; alpha ute       112150   R46576   Hs. 23239   ESTs   2.08       105054   AA133584   Hs. 26333   JM1 protein   2.08       113151   T51620   Hs. 9326   EST   2.08       118783   N75285   Hs. 50593   ESTs; Moderately similar to cytoplasmic   2.08       126748   AA249580   Hs. 239975   ESTs; Moderately similar to CDO [H.sapie   2.08       135160   U77643   Hs. 95655   secreted and transmembrane 1   2.08       107518   X60152       zinc finger protein 2   2.08       126055   N28990       yx39g04.r1 Soares melanocyte 2NbHM Homo   2.08       116982   H81933   Hs. 40317   ESTs   2.08       101756   M77235   Hs. 169331   sodium channel; voltage-gated; type V; a   2.08       116935   H75763   Hs. 53468   ESTs   2.08       118556   N68408   Hs. 194637     Homo sapiens  mRNA; cDNA DKFZp564D113 (fr   2.08       129812   L07807   Hs. 166161   dynamin 1   2.08       121946   AA429411   Hs. 104888   ESTs   2.08       133843   AA489045   Hs. 76691     Homo sapiens  clone 25100 mRNA sequence;   2.08       122170   AA435744   Hs. 163913   ESTs   2.08       122399   AA446449   Hs. 231112   EST   2.08       105775   AA348274   Hs. 6664   ESTs   2.08       123943   AA621553   Hs. 112998   ESTs   2.08       105771   AA347967   Hs. 256267   neuroblastoma RAS viral (v-ras) oncogene   2.08       114454   AA021091   Hs. 226208   ESTs   2.08       125802   R78852   Hs. 151099   ESTs   2.08       131556   AA442853   Hs. 2869   cyclin-dependent kinase 5; regulatory su   2.08       118837   N79836   Hs. 216338   ESTs   2.08       107345   U26209   Hs. 102307   solute carrier family 13 (sodium-depende   2.08       131324   H58690   Hs. 25625   ESTs   2.08       105233   AA216759   Hs. 191132   ESTs   2.07       112886   T03864   Hs. 7436   putative acyltransferase   2.07       120252   AA169400   Hs. 152701   DKFZP434F124 protein   2.07       114867   AA235310   Hs. 52899   ESTs; Moderately similar to !!!! ALU SUB   2.07       106715   AA464955   Hs. 126062   ESTs; Weakly similar to EPIDERMAL GROWTH   2.07       125560   R51281   Hs. 13692   ESTs; Highly similar to PROTEIN TSG24 [M   2.07       112270   R53021   Hs. 203358   ESTs   2.07       134626   S82198   Hs. 8709   caldecrin (serum calcium decreasing fact   2.07       115723   AA417345   Hs. 54846   ESTs   2.07       123895   AA621192   Hs. 112949   EST   2.07       119906   W85818       ESTs; Moderately similar to !!!! ALU SUB   2.07       108559   AA085161       zn12c5.s1 Stratagene hNT neuron (#937233   2.07                   IMAGE: 54728 3′ similar to TR: G1151228 G       101246   L33799   Hs. 202097   procollagen C-endopeptidase enhancer   2.07       100663   HG2915-HT3059       Major Histocompatibility Complex, Class I, E (Gb: M20022)   2.07       114178   Z39063   Hs. 17930   Humn DNA seq frm clone 1033B10 on chr 6p   2.07                   for GalT3 (beta3-Galactosyltransferase)       125672   AA152281   Hs. 78601   uroporphyrinogen decarboxylase   2.07       118052   N53360   Hs. 165133   ESTs   2.07       102387   U41163   Hs. 229731   solute carrier family 6 (neurotransmitte   2.07       127305   AA535148   Hs. 255277   ESTs   2.07       101182   L19711   Hs. 76111   dystroglycan 1 (dystrophin-associated gl   2.07       131111   R33245   Hs. 23076   ESTs; Weakly similar to putative [C.eleg   2.07       112441   R63388   Hs. 28412   ESTs   2.06       117796   N48571   Hs. 46689   EST   2.06       116099   AA456309   Hs. 58831   regulator of Fas-induced apoptosis   2.06       125559   AA307550   Hs. 119571   collagen; type III; alpha 1 (Ehlers-Danl   2.06       135271   AA397763   Hs. 97562   ESTs   2.06       106083   AA418545   Hs. 31659   thyroid hormone receptor-associated prot   2.06       133419   U67369   Hs. 73172   growth factor independent 1   2.06       127816   AA743646   Hs. 120604   ESTs   2.06       127502   AA614422   Hs. 183502   ESTs   2.06       129371   M10321   Hs. 110802   von Willebrand factor   2.06       108417   AA075716       zm89e5.s1 Stratagene ovarian cancer (#93   2.06                   CLUSTERIN PRECURSOR (HUMAN);, mRNA sequ       102837   U94585   Hs. 13495   requiem; apoptosis response zinc finger   2.06       124226   H62396   Hs. 190266   ESTs   2.06       102254   U28131       Human HMGI-C chimeric transcript mRNA, p   2.06       128472   X87212   Hs. 10029   cathepsin C   2.06       107545   Z82022   Hs. 26433   dolichyl-phosphate (UDP-N-acetylglucosam   2.06       135311   M36089   Hs. 98493   X-ray repair complementing defective rep   2.06       121727   AA420973   Hs. 104234   ESTs   2.06       131846   U02619   Hs. 331   general transcription factor IIIC; polyp   2.06       120415   AA235810   Hs. 182522   ESTs   2.06       110529   H57686   Hs. 37486   ESTs   2.06       104996   AA112307   Hs. 105894     Homo sapiens  mRNA; cDNA DKFZp434G231 (fr   2.06       110351   H41222   Hs. 196459   ESTs   2.06       131261   AA223746   Hs. 171776   inositol(myo)-1(or 4)-monophosphatase 1   2.06       110585   H62223   Hs. 133526   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.06       129420   AA234259   Hs. 99816   ESTs   2.06       103796   AA112595   Hs. 31146   Human DNA sequence from clone 1042K10 on   2.06                   lyase (EC 4.3.2.2; Adenylosuccinase; AS                   3). Contains ESTs; STSs; GS       119782   W72982   Hs. 58262   ESTs   2.06       108641   AA112059       ATP synthase; H+ transporting; mitochond   2.06       134875   U66672   Hs. 180513   ATP-binding cassette; sub-family A (ABC1   2.06       106832   AA482015   Hs. 30114   ESTs; Highly similar to C8 [ H. sapiens ]   2.06       109403   AA224413   Hs. 86937   ESTs   2.06       115485   AA287667   Hs. 188804   ESTs   2.06       102923   X12517   Hs. 1063   small nuclear ribonucleoprotein polypept   2.06       123320   AA496792   Hs. 139572   EST   2.05       111901   R39066   Hs. 17638   ESTs   2.05       106558   AA455111   Hs. 182447   heterogeneous nuclear ribonucleoprotein   2.05       126885   AA293052   Hs. 10101   ESTs; Weakly similar to coded for by C.   2.05       113429   T85190   Hs. 179808   ESTs   2.05       102270   U30255   Hs. 75888   phosphogluconate dehydrogenase   2.05       103204   X72475   Hs. 192989     H. sapiens  mRNA for rearranged Ig kappa I   2.05       106666   AA461072   Hs. 37916   ESTs   2.05       100947   HG907-HT907       Mg44   2.05       102578   U60666   Hs. 57693   testis specific leucine rich repeat prot   2.05       105827   AA398255   Hs. 31520   ESTs   2.05       122324   AA442830   Hs. 98921   EST   2.05       101025   J04823   Hs. 81097   cytochrome c oxidase subunit VIII   2.05       115861   AA431768   Hs. 90259   ESTs; Weakly similar to alpha 1 [H.sapie   2.05       108081   AA045306   Hs. 42996   ESTs   2.05       133994   X74929   Hs. 242463   keratin 8   2.05       119131   R46700   Hs. 129692   ESTs; Moderately similar to !!!! ALU SUB   2.05       129793   AA300151   Hs. 126857   ESTs   2.05       101653   M60284   Hs. 161305   tachykinin receptor 2   2.05       120300   AA191648   Hs. 131476   ESTs   2.05       106519   AA453415   Hs. 8763   Hu DNA sequence from clone 889N15 on chr   2.05                   Thymocyte Marker CTX; the possibly alte       114291   Z40690   Hs. 123666     Homo sapiens  mRNA full length insert cDN   2.05       105747   AA293719   Hs. 30251   ESTs; Weakly similar to GLUCOSE-6-PHOSPH   2.04       125325   AA332944   Hs. 8402   adenylate cyclase 3   2.04       119978   W88623   Hs. 59190   EST   2.04       102449   U48231   Hs. 46348   bradykinin receptor B1   2.04       101454   M21812   Hs. 50889   myosin light chain 2   2.04       116086   AA455904   Hs. 86023   ESTs   2.04       102297   U32674   Hs. 198252   G protein-coupled receptor 9   2.04       130889   D57622   Hs. 20985   sin3-associated polypeptide; 30 kD   2.04       100196   D21853   Hs. 79768   KIAA0111 gene product   2.04       120967   AA398111   Hs. 97503   ESTs   2.04       105735   AA293096   Hs. 32417   ESTs   2.04       135031   R41604   Hs. 9344   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.04       104882   AA052954   Hs. 29546   ESTs   2.04       132619   AA404565   Hs. 53447   ESTs; Moderately similar to kinesin ligh   2.04       127993   AA847856   Hs. 124565   ESTs   2.04       116441   AA620299   Hs. 91696   ESTs   2.04       102272   U30610   Hs. 41682   killer cell lectin-like receptor subfami   2.04       119566   W38209       Accession not listed in Genbank   2.04       116622   D81171   Hs. 45208   ESTs; Weakly similar to collagen type VI   2.04       127182   AA248620   Hs. 166011   catenin (cadherin-associated protein); d   2.04       116870   H67146   Hs. 38564   ESTs   2.04       115448   AA284845   Hs. 165051   ESTs   2.04       127231   AA434584       zw52c03.r1 Soares_total_fetus_Nb2HF8_9w   2.04       103457   X99728         H. sapiens  NDUFV3 gene, exon 3   2.04       134737   U00802   Hs. 89434   drebrin 1   2.04       117046   H89505       yu81f4.s1 Soares fetal liver spleen 1NFL   2.04                   to contains Alu repetitive element; mR       124579   N68345   Hs. 127179   ESTs; Weakly similar to TERATOCARCINOMA-   2.04       112132   R45970   Hs. 236349   EST   2.04       132281   AA133300   Hs. 43803   leukocyte-associated Ig-like receptor 2   2.03       103668   Z83741   Hs. 248174   H2A histone family; member M   2.03       113501   T89107   Hs. 13262   ESTs   2.03       125021   T70060   Hs. 163918   ESTs   2.03       115754   AA420998   Hs. 178095   ESTs   2.03       123405   AA521370   Hs. 191708   ESTs   2.03       102054   U07695   Hs. 155227   EphB4   2.03       115627   AA401910   Hs. 119175   ESTs; Weakly similar to ZINC FINGER PROT   2.03       129252   AA234663   Hs. 109773   ESTs   2.03       103417   X96849         H. sapiens  5′ mRNA of PECAM-1 molecule   2.03       133721   U11863   Hs. 75741   amiloride binding protein 1 (amine oxida   2.03       114176   Z39059   Hs. 27267   ESTs; Weakly similar to tetraspan TM4SF   2.03       123966   C14068   Hs. 21806   ESTs; Moderately similar to similar to N   2.03       134236   D45371   Hs. 80485   adipose most abundant gene transcript 1   2.03       116381   AA598614   Hs. 65394   ESTs   2.03       103711   AA046737   Hs. 102792   ESTs   2.03       109316   AA206914   Hs. 86322   EST   2.03       123793   AA620343   Hs. 112858   ESTs   2.03       128462   M69238   Hs. 166172   aryl hydrocarbon receptor nuclear transl   2.03       117690   N40467   Hs. 93834   ESTs   2.03       113301   T67452   Hs. 13104   EST   2.03       134563   AA173430   Hs. 85335   Home sapiens mRNA; cDNA DKFZp564D1462 (f   2.03       108316   AA070160       zm69f4.s1 Stratagene neuroepithelium (#9   2.03       135239   AA454599   Hs. 19399     Homo sapiens  chromosome 19; fosmid 39554   2.03       120342   AA207105   Hs. 45068   Home sapiens mRNA; cDNA DKFZp434I143 (fr   2.02       103493   Y08976   Hs. 234759     H. sapiens  mRNA for FEV protein   2.02       114204   Z39259   Hs. 26096   ESTs   2.02       125425   H62307   Hs. 18575   ESTs; Weakly similar to KIAA0246 [H.sapi   2.02       133027   AA402624   Hs. 63236   synuclein; gamma (breast cancer-specific   2.02       131323   H54036   Hs. 25619   death-associated protein kinase 3   2.02       121515   AA412133   Hs. 104696   ESTs   2.02       129780   AA291526   Hs. 124699   ESTs   2.02       131292   AF005039   Hs. 200600   secretory carrier membrane protein 3   2.02       132973   AA035446   Hs. 214361   ESTs   2.02       103727   AA059415   Hs. 6289   growth factor receptor-bound protein 2   2.02       113174   T54659   Hs. 9779   ESTs   2.02       120964   AA398085   Hs. 142390   ESTs   2.02       134303   AA457242   Hs. 8141   etoposide-induced mRNA   2.02       128118   T81623   Hs. 21765   hypothetical protein of unknown functio   2.02       121087   AA398751   Hs. 97304   ESTs   2.02       102806   U90306       Human iroquois-class homeodomain protein   2.02       103195   X70940   Hs. 2642   eukaryotic translation elongation factor   2.02       126767   C17148       C17148 Clontech human aorta polyA+ mRNA   2.02       105179   AA189083   Hs. 21974   ESTs; Moderately similar to mBOCT [M.mus   2.02       116797   H40486       yn87a08.s1 Soares adult brain N2b5HB55Y   2.02                   3′ similar to contains Alu repetitive e       133268   AA099404   Hs. 69307   ESTs   2.02       123951   AA621721   Hs. 231130   EST   2.02       115463   AA286819   Hs. 69485   ESTs; Weakly similar to similar to other   2.02       110603   H65776   Hs. 222403   ESTs   2.02       101234   L29277   Hs. 142258   signal transducer and activator of trans   2.02       121208   AA400470   Hs. 97805   ESTs   2.02       122598   AA453465   Hs. 99329   ESTs   2.02       110668   H84882   Hs. 33791   ESTs; Weakly similar to K: Cl cotransport   2.02       117137   H96670   Hs. 42221   ESTs   2.02       119389   T88826   Hs. 90973   ESTs   2.01       102940   X13956   Hs. 24998   Human 12S RNA induced by poly(rl); poly(   2.01       100748   HG3517-HT3711       Alpha-1-Antitrypsin, 5′ End   2.01       103012   X52638   Hs. 739   6-phosphofructo-2-kinase/fructose-2; 6-bi   2.01       132755   AA609201   Hs. 182635   ESTs   2.01       130842   H39589   Hs. 20159   ESTs; Highly similar to CGI-92 protein [   2.01       133599   M64788   Hs. 75151   RAP1; GTPase activating protein 1   2.01       117250   N21081   Hs. 15299   HMBA-inducible   2.01       115124   AA256666   Hs. 39156   ESTs   2.01       128155   AA926843   Hs. 143302   ESTs   2.01       130574   AA379087   Hs. 16178   apoptosis antagonizing transcription fac   2.01       132601   R78838   Hs. 54943   fracture callus 1 (rat) homolog   2.01       117428   N27366   Hs. 43933   EST   2.01       121108   AA399053   Hs. 97529   EST   2.01       130518   X69550   Hs. 159161   Rho GDP dissociation inhibitor (GDI) alp   2.01       110606   H66049   Hs. 19085   ESTs; Weakly similar to putative p150 [H   2.01       120606   AA282956       zt15h4.s1 NCI_CGAP_GCB1  Homo sapiens  cDN                   SW: CADR_MOUSE P3938 RETINAL-CADHERIN PR   2.01       130070   T47969   Hs. 194660   ceroid-lipofuscinosis; neuronal 3; juven   2.01       130331   Z80783   Hs. 239884   H2B histone family; member L   2.01       109599   F02602   Hs. 6749   ESTs   2.01       131749   W78211   Hs. 31547   ESTs; Highly similar to NADH: ubiquinone   2.01       129463   AA376905   Hs. 111742   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.01       114880   AA235698   Hs. 65862   ESTs   2.01       114745   AA135523   Hs. 139064   EST   2.01       115637   AA402727   Hs. 76925   ESTs; Highly similar to R31167_2; partia   2.01       109043   AA159605   Hs. 72580   ESTs   2.01       128901   Z41411   Hs. 107040   ESTs   2.01       124427   N36812   Hs. 178663   ESTs   2       100673   HG3033-HT3194       Spliceosomal Protein Sap 62   2       108436   AA078801       zm94a9.s1 Stratagene colon HT29 (#937221   2       123764   AA610019   Hs. 112654   ESTs   2       129343   N70791   Hs. 180060   ESTs   2       122794   AA460254   Hs. 105043   EST   2       128688   AA161469   Hs. 103755   receptor-interacting serine-threonine ki   2       115592   AA399543   Hs. 48026   ESTs   2       111693   R22007   Hs. 23321   EST   2       113353   T79186   Hs. 14468   ESTs   2                                                    
     [0344]               TABLE 18                          B survivor vs Mets - Up in Mets                                 Pkey   Ex Accn   UniG ID   Complete Title   Ratio BS/Met                                         106024   AA412059   Hs. 111742   ESTs; Weakly similar to !!!! ALU SUBFAMI   0.17       110930   N48603   Hs. 14947   ESTs   0.18       105772   AA347973   Hs. 221132   ESTs   0.2       133271   Z48633   Hs. 6940     H. sapiens  mRNA for retrotransposon   0.2       107109   AA609943   Hs. 32793   ESTs   0.24       109593   F02506   Hs. 159591   thyroid hormone receptor interactor 8   0.24       123016   AA480103   Hs. 111730   ESTs; Weakly similar to alternatively sp   0.25       100739   HG3484-HT3678       Protein Kinase (Gb: M59287)   0.25       130252   U92014   Hs. 153527   Human clone 121711 defective mariner tra   0.26       105149   AA169253   Hs. 8958   ESTs   0.26       115412   AA283804   Hs. 193552   ESTs   0.27       105952   AA405263   Hs. 181400   ESTs   0.28       106596   AA456981   Hs. 35349   ESTs   0.28       120249   AA167567   Hs. 133325   ESTs   0.28       111676   R19414   Hs. 166459   ESTs   0.29       111161   N66767   Hs. 124145   ESTs   0.29       109364   AA215379   Hs. 50418   ESTs   0.29       132316   U28831       Human protein immuno-reactive with anti-   0.3       104030   AA363131   Hs. 222992   ESTs; Weakly similar to TRANSFORMATION-S   0.3       109825   F13663   Hs. 16798   ESTs   0.3       111110   N63165   Hs. 23618   ESTs   0.31       135315   W90583   Hs. 9853   ESTs   0.32       104792   AA029288   Hs. 29147   ESTs; Highly similar to ZINC FINGER PROT   0.33       123562   AA608893   Hs. 190065   ESTs   0.33       116079   AA455286   Hs. 54982   ESTs; Weakly similar to !!!! ALU SUBFAMI   0.33       110671   H87770   Hs. 153800   ESTs   0.33       108819   AA130986   Hs. 193253   ESTs   0.34       115558   AA393806   Hs. 1010   regulator of mitotic spindle assembly 1   0.34       104781   AA026617   Hs. 21610   ESTs; Highly similar to BAI1-associated   0.34       111236   N69324   Hs. 12526     Homo sapiens  clone 23903 mRNA sequence   0.34       113341   T77866   Hs. 189703   ESTs   0.35       125371   AI084676   Hs. 133266   ESTs; Moderately similar to Sqv-7-like p   0.35       115890   AA435853   Hs. 44114   ESTs; Weakly similar to CGI-73 protein [   0.35       113571   T91116   Hs. 15713   ESTs   0.35       121683   AA417911   Hs. 175663   ESTs   0.35       105489   AA256157   Hs. 24115   ESTs   0.35       116320   AA490866   Hs. 39429   ESTs   0.36       111917   R39882   Hs. 21397   ESTs   0.36       127568   T53722       ya91c06.r3 Stratagene placenta (#937225)   0.36       123541   AA608794   Hs. 112592   ESTs   0.36       123131   AA487207   Hs. 193272   ESTs   0.36       125069   T86914   Hs. 194485   ESTs   0.36       114757   AA136725   Hs. 161990   ESTs   0.37       132778   AA446695   Hs. 5671     Homo sapiens  clone 23926 mRNA sequence   0.37       123132   AA487233   Hs. 106711   eukaryotic translation initiation factor   0.37       134029   AA378597   Hs. 143601   ESTs; Moderately similar to 67A9.b [D.me   0.37       126956   AI434405   Hs. 171957   triple functional domain (PTPRF interact   0.38       106869   AA487563   Hs. 188813   ESTs   0.38       107818   AA020957   Hs. 167948   ESTs   0.38       129974   K00629   Hs. 199300   Human kpni repeat mma (cdna clone pcd-k   0.38       129477   D49728   Hs. 1119   nuclear receptor subfamily 4; group A; m   0.38       119369   T79020   Hs. 245915   ESTs; Weakly similar to kinase-related p   0.39       114021   W91995   Hs. 16145   ESTs   0.39       122024   AA431296   Hs. 139433   EST   0.39       130014   N50959   Hs. 143102   amine oxidase; copper containing 2 (reti   0.39       110163   H19326   Hs. 22073   ESTs; Highly similar to J KAPPA-RECOMBIN   0.39       104641   AA004652   Hs. 18564   ESTs   0.39       124777   R41933   Hs. 140237   ESTs   0.39       125382   AA713494   Hs. 194660   ceroid-lipofuscinosis; neuronal 3; juven   0.4       120406   AA234999   Hs. 111279   ESTs; Weakly similar to unnamed protein   0.4       132734   R23653   Hs. 164250   ESTs   0.4       117001   H84719   Hs. 40721   EST   0.4       120905   AA371602   Hs. 182930   ESTs; Highly similar to PHOSPHATIDYLINOS   0.4       125488   AA355158   Hs. 41181     Homo sapiens  mRNA; cDNA DKFZp727C191 (fr   0.4       121989   AA430044   Hs. 193784     Homo sapiens  mRNA; cDNA DKFZp586K1922 (f   0.4       127921   AA806616   Hs. 209523   ESTs   0.4       119830   W74700   Hs. 53478   ESTs   0.41       106292   AA435571   Hs. 148560   ESTs   0.41       102762   U82303   Hs. 123080     Homo sapiens  unknown protein mRNA; parti   0.41       113518   T89731       ye11f06.s1 Stratagene lung (#937210) H.s                   to contains Alu repetitive element;cont   0.41       100635   HG2724-HT2820       Oncogene Tls/Chop, Fusion Activated   0.41       113319   T70356   Hs. 193141   ESTs; Weakly similar to coding sequence   0.41       121319   AA402935   Hs. 194242   ESTs; Weakly similar to !!!! ALU CLASS B   0.42       111818   R34382   Hs. 24779   ESTs   0.42       104883   AA052959   Hs. 177409   ESTs; Highly similar to dJ1119D9.2 [H.sa   0.42       129258   W95592   Hs. 251946   ESTs; Moderately similar to POLYADENYLAT   0.42       130576   T86475   Hs. 16193     Homo sapiens  mRNA; cDNA DKFZp586B211 (fr   0.43       106354   AA443271   Hs. 26764   KIAA0546 protein   0.43       108841   AA132524   Hs. 70614   ESTs   0.43       113922   W80741   Hs. 37890   ESTs   0.43       120997   AA398285   Hs. 97598   EST   0.43       108158   AA054597   Hs. 221935   ESTs   0.43       124516   N58185   Hs. 131830   ESTs   0.43       114477   AA032013   Hs. 144260   EST   0.43       104290   C16652   Hs. 107205     Homo sapiens  mRNA; cDNA DKFZp434L2221 (f   0.43       126700   AI318412   Hs. 108258   actin binding protein; macrophin (microf   0.44       110887   N38770   Hs. 4283   ESTs   0.44       116141   AA460420   Hs. 44949   ESTs   0.44       110689   H93046   Hs. 15571   ESTs   0.44       115314   AA280583   Hs. 256501   ESTs   0.44       110904   N39453   Hs. 27371     Homo sapiens  mRNA; cDNA DKFZp566J123 (fr   0.44       109482   AA233375   Hs. 78085   ESTs   0.44       102284   U31449   Hs. 11881   transmembrane 4 superfamily member 4   0.44       118654   N70582   Hs. 49892   ESTs   0.44       115334   AA281244   Hs. 65300   ESTs   0.44       113149   T51588       ESTs; Moderately similar to !!!! ALU SUB   0.44       113721   T97931   Hs. 18190   EST   0.44       111299   N73808   Hs. 24936   ESTs   0.44       103778   AA094107   Hs. 7187   ESTs; Weakly similar to similar to glyco   0.44       113204   T57865   Hs. 10310   EST   0.44       100315   D50857   Hs. 82295   dedicator of cyto-kinesis 1   0.44       115254   AA279024   Hs. 194437   ESTs   0.44       125500   H46104   Hs. 244624   ESTs   0.44       117387   N26011   Hs. 53810   ESTs   0.45       135113   W42450   Hs. 206833   ESTs   0.45       124517   N58204   Hs. 199945   ESTs   0.45       120379   AA227849   Hs. 238380   Human endogenous retroviral protease mRN   0.45       119205   R91954   Hs. 153699   ESTs   0.45       128266   T70341   Hs. 131897   ESTs   0.45       104106   AA422123   Hs. 42457   ESTs   0.45       115864   AA432080   Hs. 81200   ESTs   0.45       113771   W02695   Hs. 18714   ESTs   0.45       126515   AI124649   Hs. 252708     Homo sapiens  mRNA; cDNA DKFZp586O031 (fr   0.45       127823   AA524806   Hs. 78869   transcription elongation factor A (SII);   0.45       116665   F04405   Hs. 223654   EST   0.45       106355   AA443272   Hs. 27836   ESTs   0.45       132693   AA621429   Hs. 55075   KIAA0410 gene product   0.45       107388   W01587   Hs. 173319   ESTs   0.45       110688   H93021   Hs. 182937   peptidylprolyl isomerase A (cyclophilin   0.46       116893   H69569   Hs. 191316   EST   0.46       105375   AA236542   Hs. 9512   ESTs; Moderately similar to !!!! ALU SUB   0.46       115601   AA400277   Hs. 48849   ESTs   0.46       106896   AA489707   Hs. 29896   ESTs; Weakly similar to proline-rich pro   0.46       111770   R27975   Hs. 187469   ESTs   0.46       115663   AA405838   Hs. 40507   ESTs   0.46       131404   AA504744   Hs. 26461   ESTs; Weakly similar to gc-rich sequence   0.46       108622   AA101828   Hs. 189956   ESTs   0.46       128286   AI025771   Hs. 144090   ESTs   0.46       105760   AA338960   Hs. 28170   ESTs   0.46       100020           AFFX control: BioB-3   0.46       105209   AA205072   Hs. 227743   KIAA0980 protein   0.47       111975   R41724   Hs. 149566   ESTs   0.47       114688   AA121403   Hs. 144331   ESTs   0.47       116994   H83918   Hs. 40528   ESTs   0.47       118401   N64762   Hs. 49053   EST   0.47       110997   N52540   Hs. 74316   desmoplakin (DPI; DPII)   0.47       123791   AA620331   Hs. 245351   EST   0.47       109858   H02266   Hs. 167451   ESTs   0.47       115470   AA287122   Hs. 48391   ESTs   0.47       130606   AA402109   Hs. 16593   ESTs   0.47       116067   AA454827   Hs. 124823   ESTs   0.47       125881   AA775807   Hs. 150741   2′;3′-cyclic nucleotide 3′ phosphodieste   0.47       124028   F04112   Hs. 177178   ESTs   0.47       108995   AA155574   Hs. 172702   ESTs   0.47       125102   T95105   Hs. 173772   ESTs   0.47       110421   H48462   Hs. 36093   ESTs; Weakly similar to reverse transcri   0.47       105658   AA282914   Hs. 10176   ESTs   0.47       129046   AA195678   Hs. 108258   actin binding protein; macrophin (microf   0.47       113639   T95128   Hs. 17529   ESTs   0.48       132575   AA045365   Hs. 5188   ESTs; Weakly similar to 60S RIBOSOMAL PR   0.48       132592   AA129390   Hs. 5285   ESTs   0.48       107619   AA004955   Hs. 60015   ESTs   0.48       118664   N70907   Hs. 230619   EST   0.48       127612   AA917801   Hs. 116076   ESTs   0.48       112319   R55615   Hs. 26432   ESTs; Weakly similar to finger protein H   0.48       113635   T95087   Hs. 15543   ESTs   0.48       119344   T62969   Hs. 193348   ESTs   0.48       121080   AA398720   Hs. 177953   ESTs   0.48       133686   X83378   Hs. 211614   chloride channel 6   0.48       130395   R54534   Hs. 87889   helicase-moi   0.49       127530   AA563806   Hs. 145728   ESTs   0.49       132971   AA033951   Hs. 61700   ESTs   0.49       127132   AA721156   Hs. 190440   ESTs   0.49       129980   T72661   Hs. 13969   ESTs   0.49       105323   AA234112   Hs. 29075   ESTs   0.49       114439   AA018937   Hs. 128629   ESTs   0.49       107632   AA007242   Hs. 60179   EST   0.49       130952   AB002296   Hs. 21560   Human mRNA for KIAA0298 gene; complete c   0.49       127595   AA927308   Hs. 130464   ESTs   0.49       124276   H83465   Hs. 221934   ESTs   0.49       125935   H30721   Hs. 30172   ESTs   0.49       131275   U45974   Hs. 25156   Human phosphatidylinositol (4;5) bisphos   0.49       131196   C20633   Hs. 24129   ESTs   0.49       125505   AI127843   Hs. 155071   ESTs   0.5       113327   T71776   Hs. 12097   ESTs   0.5       104709   AA017146   Hs. 34579   ESTs; Moderately similar to !!!! ALU SUB   0.5       115772   AA423972   Hs. 8154   ESTs   0.5       118296   N63150   Hs. 48723   ESTs   0.5       131453   C20596   Hs. 26985   KIAA0457 protein   0.5       104734   AA019528   Hs. 32677   ESTs   0.5       119358   T70550   Hs. 193651   ESTs; Weakly similar to alternatively sp   0.5                                                    
     [0345]               TABLE 19                          B survivor vs Mets - Up in B survivor                                 Pkey   Ex Accn   UniG_ID   Complete Title   Ratio BS/Met                                         333601           CH22_FGENES.213_4   5.5       325300           CH.11_hs gi|5866908   4.67       333642           CH22_FGENES.231_2   4.64       333591           CH22_FGENES.208_4   4.46       332859           CH22_FGENES.27_2   4.39       304013   AW518573   Hs. 156110   Immunoglobulin kappa variable 1D-8   4.23       333791           CH22_FGENES.274_10   4.18       327641           CH.04_hs gi|5867890   4.03       321172   H49160   Hs. 133472   ESTs   3.9       334125           CH22_FGENES.334_4   3.88       333646           CH22_FGENES.234_2   3.88       326554           CH.19_hs gi|5867308   3.84       333650           CH22_FGENES.238_3   3.82       333647           CH22_FGENES.235_2   3.79       333626           CH22_FGENES.224_2   3.68       314671   AW236550   Hs. 131914   ESTs   3.68       310847   AI420523   Hs. 161282   ESTs   3.67       333657           CH22_FGENES.241_2   3.65       338522           CH22_EM: AC005500.GENSCAN.395-36   3.64       329464           CH.Y_hs gi|6456788   3.6       328868           CH.07_hs gi|6381930   3.6       333637           CH22_FGENES.229_2   3.59       329737           CH.14_p2 gi|6065779   3.5       317828   AI791749   Hs. 128896   ESTs   3.44       330520   M96995   Hs. 6289   growth, factor receptor-bound protein 2   3.44       339271           CH22_BA354I12.GENSCAN.11-2   3.44       314927   AI735482   Hs. 159580   ESTs   3.42       334782           CH22_FGENES.432_7   3.42       313138   AW138842   Hs. 196669   ESTs   3.4       332650   H51596   Hs. 5541   ATPase; Ca++ transporting; ubiquitous   3.38       338648           CH22_EM: AC005500.GENSCAN.460-6   3.38       325677           CH.14_hs gi|5867017   3.34       312639   H50648   Hs. 213221   ESTs; Weakly similar to !!!! ALU SUBFAMI   3.33       326545           CH.19_hs gi|5867307   3.32       318354   R44616   Hs. 138280   ESTs; Moderately similar to !!!! ALU SUB   3.3       308385   AI625428       EST singleton (not in UniGene) with exon   3.26       328569           CH.07_hs gi|6004480   3.26       328582           CH.07_hs gi|6006033   3.24       310975   AI492857   Hs. 170940   ESTs   3.24       336883           CH22_FGENES.322-2   3.21       324425   AW236939   Hs. 172154   ESTs   3.2       337870           CH22_EM: AC005500.GENSCAN.48-3   3.19       306624   AI001043       EST singleton (not in UniGene) with exon   3.17       319091   Z45264       EST cluster (not in UniGene)   3.16       335247           CH22_FGENES.516_8   3.12       324945   AA088768       EST cluster (not in UniGene)   3.1       319468   R06504       EST cluster (not in UniGene)   3.09       301635   AI590720   Hs. 192662   ESTs; Weakly similar to ZINC FINGER PROT   3.08       321215   AW378128   Hs. 120243   ESTs; Weakly similar to CGI-56 protein [   3.04       328507           CH.07_hs gi|5868473   3.03       330266           CH.05_p2 gi|6671885   3.02       326249           CH.17_hs gi|5867263   3.01       325649           CH.14_hs gi|6588011   2.99       304575   AA496437       EST singleton (not in UniGene) with exon   2.98       304559   AA488050       EST singleton (not in UniGene) with exon   2.97       338412           CH22_EM: AC005500.GENSCAN.341-25   2.96       308707   AI769997       EST singleton (not in UniGene) with exon   2.95       313027   N34307   Hs. 184003   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.95       306590   AI000246       EST singleton (not in UniGene) with exon   2.95       306183   AA922622       EST singleton (not in UniGene) with exon   2.94       308611   AI735372   Hs. 203820   EST; Moderately similar to TRANSLATIONAL   2.94       332454   T63265   Hs. 11186   ESTs; Weakly similar to transformation-r   2.94       330061           CH.17_p2 gi|6721261   2.94       317671   AW138139   Hs. 244598   ESTs   2.93       338705           CH22_EM: AC005500.GENSCAN.480-4   2.93       333737           CH22_FGENES.261_1   2.9       337756           CH22_EM: AC000097.GENSCAN.109-3   2.9       333572           CH22_FGENES.189_1   2.89       335349           CH22_FGENES.539_2   2.89       328835           CH.07_hs gi|5868339   2.89       319886   AA984628       EST cluster (not in UniGene)   2.88       311247   AI655313   Hs. 197692   ESTs   2.87       303887   R72672   Hs. 193484   ESTs; Weakly similar to Similarity with   2.86       337564           CH22_C65E1.GENSCAN.1-7   2.85       333225           CH22_FGENES.107_3   2.84       314938   AA515635       EST cluster (not in UniGene)   2.83       305803   AA846052       EST singleton (not in UniGene) with exon   2.83       305264   AA679505       EST singleton (not in UniGene) with exon   2.83       332646   AA386264   Hs. 5337   isocitrate dehydrogenase 2 (NADP+); mito   2.81       338508           CH22_EM: AC005500.GENSCAN.391-1   2.81       308097   AI475411       EST singleton (not in UniGene) with exon   2.81       301130   AW194167   Hs. 149418   ESTs; Weakly similar to salivary proline   2.8       325571           CH.12_hs gi|6552439   2.8       307054   AI148181   Hs. 176835   EST   2.8       337456           CH22_FGENES.777-2   2.79       317870   AI797066   Hs. 201995   ESTs   2.79       303171   AA065003   Hs. 64179   hypothetical protein   2.78       333717           CH22_FGENES.253_3   2.76       303778   AW505368       EST cluster (not in UniGene) with exon h   2.76       304918   AA602697       EST singleton (not in UniGene) with exon   2.76       319373   R00371       EST cluster (not in UniGene)   2.75       336072           CH22_FGENES.685_4   2.74       306023   AA897764       EST singleton (not in UniGene) with exon   2.74       336127           CH22_FGENES.701_15   2.74       337355           CH22_FGENES.728-1   2.73       337885           CH22_EM: AC005500.GENSCAN.54-3   2.73       308506   AI686791   Hs. 119598   ribosomal protein L3   2.73       300629   AA152119   Hs. 155101   ATP synthase; H+ transporting; mitochond   2.73       333043           CH22_FGENES.70_4   2.72       327736           CH.05_hs gi|5867940   2.72       333007           CH22_FGENES.60_4   2.72       321966   AL122111       EST cluster (not in UniGene)   2.72       323179   AW452576   Hs. 156875   ESTs   2.72       332459   AA609625   Hs. 112933     Homo sapiens  Tax interaction protein 40   2.71       326224           CH.17_hs gi|5867230   2.71       329114           CH.X_hs gi|5868650   2.7       333577           CH22_FGENES.196_2   2.69       300413   AW090347   Hs. 243443   ESTs   2.67       304055   R07994       EST singleton (net in UniGene) with exon   2.67       301013   AI935304   Hs. 125262   DKFZP586G1624 protein   2.67       337848           CH22_EM: AC005500.GENSCAN.33-1   2.66       327946           CH.06_hs gi|5868206   2.66       306300   AA937573       EST singleton (not in UniGene) with exon   2.66       331071   R01646   Hs. 200538   ESTs   2.65       304841   AA587541       EST singleton (not in UniGene) with exon   2.65       301321   AI860987   Hs. 189097   ESTs   2.65       311280   AI767957   Hs. 197737   ESTs; Weakly similar to Y38A8.1 gene pro   2.65       338843           CH22_DJ246D7.GENSCAN.8-1   2.64       335720           CH22_FGENES.599_23   2.64       333670           CH22_FGENES.245_4   2.64       313588   AI803591   Hs. 209667   ESTs   2.64       335750           CH22_FGENES.602_4   2.63       333240           CH22_FGENES.111_4   2.63       332721   R70212   Hs. 79630   CD79A antigen (immunoglobulin-associated   2.62       338747           CH22_EM: AC005500.GENSCAN.511-1   2.62       303582   AA377444       EST cluster (not in UniGene) with exon h   2.62       336898           CH22_FGENES.330-1   2.62       325835           CH.16_hs gi|6552452   2.62       301660   F13112       EST cluster (not in UniGene) with exon h   2.61       335968           CH22_FGENES.652_1   2.61       336705           CH22_FGENES.63-2   2.6       309815   AW292760       EST singleton (not in UniGene) with exon   2.6       339220           CH22_FF113D11.GENSCAN.6-15   2.6       308582   AI709056       EST singleton (not in UniGene) with exon   2.6       334260           CH22_FGENES.367_8   2.6       309963   AW449073       EST singleton (not in UniGene) with exon   2.6       300178   AI282665   Hs. 166969   ESTs   2.59       335690           CH22_FGENES.596_5   2.59       308127   AI492187       EST singleton (not in UniGene) with exon   2.59       337835           CH22_EM: AC005500.GENSCAN.22-4   2.58       333251           CH22_FGENES.116_3   2.58       330319           CH.08_p2 gi|5932415   2.58       314490   AI758114   Hs. 197032   ESTs   2.57       305934   AA878815   Hs. 75442   albumin   2.57       329665           CH.14_p2 gi|6272129   2.57       328558           CH.07_hs gi|5868489   2.57       336094           CH22_FGENES.691_3   2.57       307899   AI380270       EST singleton (not in UniGene) with exon   2.57       339312           CH22_BA354|12.GENSCAN.22-10   2.57       336442           CH22_FGENES.827_8   2.57       317894   R60848       EST cluster (not in UniGene)   2.56       330435   HG2689-HT2785       Mucin 5b, Tracheobronchial (Gb: X74955)   2.56       327304           CH.01_hs gi|5867494   2.56       308859   AI830787       EST singleton (not in UniGene) with exon   2.55       302224   AI951549   Hs. 161166   KIAA1094 protein   2.55       304324   AA137045       EST singleton (not in UniGene) with exon   2.54       338090           CH22_EM: AC005500.GENSCAN.176-3   2.53       334797           CH22_FGENES.434_5   2.52       303535   AL043430       EST cluster (not in UniGene) with exon h   2.52       339037           CH22_DA59H18.GENSCAN.26-5   2.52       327846           CH.05_hs gi|6531962   2.52       325271           CH.11_hs gi|5866901   2.52       312385   R42885   Hs. 215555   ESTs   2.51       302816   AI733918   Hs. 204112   ESTs; Weakly similar to alternatively sp   2.51       316941   AW449871   Hs. 124591   ESTs   2.5       300184   AI285912   Hs. 254515   ESTs   2.5       333762           CH22_FGENES.270_2   2.5       317028   AA962623   Hs. 189144   ESTs; Weakly similar to RENAL SODIUM-DEP   2.5       326266           CH.17_hs gi|5867264   2.49       326005           CH.16_hs gi|5867112   2.49       301971   AJ003125   Hs. 120330   a disintegrin-like and metalloprotease (   2.48       326539           CH.19_hs gi|5867307   2.48       338896           CH22_DJ32I10.GENSCAN.9-4   2.48       306773   AI040750       EST singleton (not in UniGene) with exon   2.47       336279           CH22_FGENES.763_3   2.47       321017   AL050345   Hs. 227637   hypothetical protein   2.47       306090   AA908609       EST singleton (not in UniGene) with exon   2.47       333216           CH22_FGENES.104_8   2.46       338593           CH22_EM: AC005500.GENSCAN.435-2   2.46       333587           CH22_FGENES.205_2   2.46       300396   AW295466   Hs. 232051   ESTs   2.45       304693   AA554263       EST singleton (not in UniGene) with exon   2.45       338934           CH22_DJ32I10.GENSCAN.18-2   2.45       325751           CH.14_hs gi|6682474   2.45       334137           CH22_FGENES.337_1   2.45       333581           CH22_FGENES.200_1   2.45       302083   AI422807   Hs. 134012   C1q-related factor   2.44       307318   AI208577       EST singleton (not in UniGene) with exon   2.44       302181   AW374284   Hs. 157732     Homo sapiens  chromosome 19; cosmid R2689   2.44       337425           CH22_FGENES.761-1   2.44       336227           CH22_FGENES.730_2   2.44       314657   AI015953   Hs. 125265   ESTs   2.44       338529           CH22_EM: AC005500.GENSCAN.398-10   2.44       333680           CH22_FGENES.247_7   2.43       324834   AJ003258   Hs. 250891   ESTs   2.43       305093   AA642917       EST singleton (not in UniGene) with exon   2.43       335787           CH22_FGENES.611_3   2.43       311704   AI655206   Hs. 121512   ESTs; Moderately similar to kinesin like   2.43       329382           CH.X_hs gi|5868868   2.42       334785           CH22_FGENES.432_10   2.42       330130           CH.21_p2 gi|6002196   2.42       327206           CH.01_hs gi|5867447   2.41       319235   F11330   Hs. 177633   ESTs   2.41       334691           CH22_FGENES.420_4   2.4       327610           CH.04_hs gi|5867868   2.4       327646           CH.04_hs gi|5867894   2.4       337093           CH22_FGENES.465-18   2.4       335081           CH22_FGENES.488_4   2.4       333576           CH22_FGENES.193_2   2.4       337604           CH22_C20H12.GENSCAN.16-5   2.4       329879           CH.15_p2 gi|6466518   2.4       328444           CH.07_hs gi|5868420   2.39       335700           CH22_FGENES.598.1   2.39       331255   Z41009   Hs. 21446   ESTs; Weakly similar to HYPOTHETICAL PRO   2.39       327927           CH.06_hs gi|5868173   2.39       334354           CH22_FGENES.377_1   2.39       308517   AI689279       EST singleton (not in UniGene) with exon   2.39       303669   AW499648   Hs. 233750   copine V   2.39       333648           CH22_FGENES.237_2   2.38       318318   AI653893   Hs. 174463   ESTs; Weakly similar to alpha3b subunit   2.38       338336           CH22_EM: AC005500.GENSCAN.310-8   2.38       304125   H40976       EST singleton (not in UniGene) with exon   2.38       304983   AA617786       EST singleton (not in UniGene) with exon   2.38       334935           CH22_FGENES.464_3   2.38       314326   AW170057   Hs. 133179   ESTs   2.38       330406   D49490   Hs. 76901   for protein disulfide isomerase-related   2.38       307646   AI302236       EST singleton (not in UniGene) with exon   2.38       338911           CH22_DJ32I10.GENSCAN.11-3   2.38       319952   T79532   Hs. 225725   ESTs; Moderately similar to CGI-101 prot   2.37       336878           CH22_FGENES.318-5   2.37       338140           CH22_EM: AC005500.GENSCAN.203-6   2.37       300564   AI383878   Hs. 225588   ESTs   2.37       304635   AA523976       EST singleton (not in UniGene) with exon   2.37       334091           CH22_FGENES.327_47   2.37       336328           CH22_FGENES.812_7   2.37       325310           CH.11_hs gi|5866864   2.37       338043           CH22_EM: AC005500.GENSCAN.153-2   2.37       307090   AI161024       EST singleton (not in UniGene) with exon   2.37       335768           CH22_FGENES.607_2   2.37       334969           CH22_FGENES.466_2   2.37       333640           CH22_FGENES.230_2   2.36       330002           CH.16_p2 gi|6623963   2.36       338829           CH22-DJ246D7.GENSCAN.5-12   2.36       323808   AW250114       EST cluster (not in UniGene)   2.36       327755           CH.05_hs gi|5867955   2.35       306426   AA975039       EST singleton (not in UniGene) with exon   2.35       336481           CH22_FGENES.830_1   2.35       335163           CH22_FGENES.502_7   2.35       322012   AL137357       EST cluster (not in UniGene)   2.35       337345           CH22_FGENES.723-1   2.35       334625           CH22_FGENES.414_3   2.35       320957   AI878933       EST cluster (not in UniGene)   2.35       334915           CH22_FGENES.457_4   2.35       336295           CH22_FGENES.787_1   2.35       321556   N46402   Hs. 14570   ESTs   2.35       338491           CH22_EM: AC005500.GENSCAN.385-2   2.35       335517           CH22_FGENES.571_34   2.34       330639   X90872   Hs. 75854   SULT1C sulfotransferase   2.34       310383   AI263102   Hs. 145596   ESTs   2.34       331526   N49967   Hs. 46624   ESTs   2.34       334396           CH22_FGENES.381_2   2.34       332993           CH22_FGENES.57_2   2.34       327487           CH.02_hs gi|5867785   2.34       335920           CH22_FGENES.636_16   2.33       336463           CH22_FGENES.829_22   2.33       319000   Z44318       EST cluster (not in UniGene)   2.33       332992           CH22_FGENES.57_1   2.33       332920           CH22_FGENES.37_6   2.33       337590           CH22_C20H12.GENSCAN.6-5   2.33       327059           CH.21_hs gi|6531965   2.33       334399           CH22_FGENES.382_5   2.33       300982   AA837754       EST cluster (not in UniGene) with, exon h   2.32       327430           CH.02_hs gi|5867754   2.32       326808           CH.20_hs gi|6682504   2.32       309324   AW015373       EST singleton (not in UniGene) with exon   2.32       329779           CH.14_p2 gi|6002090   2.32       330492   M25809   Hs. 64173   ATPase; H+ transporting; lysosomal (vacu   2.31       330080           CH.19_p2 gi|6015314   2.31       334342           CH22_FGENES.375_20   2.31       336306           CH22_FGENES.793_5   2.31       336400           CH22_FGENES.823_15   2.31       323735   AA323714       EST cluster (not in UniGene)   2.31       334496           CH22_FGENES.397_12   2.31       336075           CH22_FGENES.687_1   2.31       335566           CH22_FGENES.580_1   2.31       337657           CH22_EM: AC000097.GENSCAN.32-9   2.31       327816           CH.05_hs gi|5867968   2.3       308465   AI672480       EST singleton (not in UniGene) with exon   2.3       330112           CH.19_p2 gi|6015238   2.3       304465   AA421948       EST singleton (not in UniGene) with exon   2.3       308449   AI660854       EST singleton (not in UniGene) with exon   2.3       328171           CH.06_hs gi|5868071   2.3       328271           CH.06_hs gi|6552415   2.3       328803           CH.07_hs gi|6004475   2.3       330063           CH.19_p2 gi|6165044   2.29       312281   H11643       EST cluster (not in UniGene)   2.29       328974           CH.09_hs gi|5868520   2.29       333859           CH22_FGENES.290_18   2.29       326253           CH.17_hs gi|5867263   2.29       325703           CH.14_hs gi|5867028   2.29       338925           CH22_DJ32I10.GENSCAN.14-3   2.29       328552           CH.07_hs gi|5868489   2.29       337244           CH22_FGENES.646-8   2.29       314770   AI732722   Hs. 187694   ESTs   2.29       324560   AW502208       EST cluster (not in UniGene)   2.29       310603   AW376860   Hs. 156398   ESTs   2.29       337363           CH22_FGENES.733-2   2.29       308015   AI440174   Hs. 228907   EST; Weakly similar to GUANINE NUCLEOTID   2.28       309206   AI961962       EST singleton (not in UniGene) with exon   2.28       337455           CH22_FGENES.777-1   2.28       327605           CH.03_hs gi|6004463   2.28       301611   W22172   Hs. 59038   ESTs   2.28       317222   AI206964   Hs. 130051   ESTs   2.28       338278           CH22_EM: AC005500.GENSCAN.290-3   2.28       337291           CH22_FGENES.673-2   2.27       337913           CH22_EM: AC005500.GENSCAN.59-10   2.27       306406   AA971973       EST singleton (not in UniGene) with exon   2.27       332947           CH22_FGENES.47_10   2.27       321763   W01148       EST cluster (not in UniGene)   2.27       304424   AA293494       EST singleton (not in UniGene) with exon   2.27       303782   T64737       EST cluster (not in UniGene) with exon h   2.27       326943           CH.21_hs gi|6004446   2.27       324977   R14439   Hs. 209194   ESTs   2.27       325480           CH.12_hs gi|5866957   2.27       327743           CH.05_hs gi|5867944   2.27       333221           CH22_FGENES.105_1   2.26       336498           CH22_FGENES.833_3   2.26       321583   H84421       EST cluster (not in UniGene)   2.26       334191           CH22_FGENES.352_6   2.26       327089           CH.21_hs gi|6531965   2.26       310001   F18939   Hs. 153827   ESTs   2.26       304056   R08577       EST singleton (not in UniGene) with exon   2.25       324700   AW504745   Hs. 103913   ESTs; Moderately similar to !!!! ALU SUB   2.25       330637   X86371   Hs. 95659   lethal giant larvae (Drosophila) homolog   2.25       307642   AI302103       EST singleton (not in UniGene) with exon   2.25       336985           CH22_FGENES.402-6   2.25       334425           CH22_FGENES.384_13   2.25       321216   AI078042   Hs. 126691   ESTs   2.25       315785   AW205946   Hs. 150319   ESTs   2.25       305809   AA853998   Hs. 124580   EST   2.25       331334   AA284858   Hs. 89134   ESTs   2.25       317131   AI991125   Hs. 189109   ESTs   2.25       334216           CH22_FGENES.358_1   2.24       330330           CH.08_p2 gi|5670267   2.24       326923           CH.21_hs gi|6456782   2.24       333774           CH22_FGENES.272_5   2.24       324311   AA443061   Hs. 202520   ESTs   2.24       338551           CH22_EM: AC005500.GENSCAN.413-2   2.24       306716   AI024916   Hs. 251354   ESTs   2.24       337689           CH22_EM: AC000097.GENSCAN.77-5   2.24       300079   AI192520   Hs. 147178   EST   2.23       334617           CH22_FGENES.411_16   2.23       336890           CH22_FGENES.326-10   2.23       334495           CH22_FGENES.397_10   2.23       327301           CH.01_hs gi|5867493   2.23       337856           CH22_EM: AC005500.GENSCAN.41-3   2.23       307072   AI150424   Hs. 146817   EST   2.23       330515   M85247         H. sapiens  dopamine D1A receptor gene, co   2.22       325943           CH.16_hs gi|5867138   2.22       338947           CH22_DJ32I10.GENSCAN.21-4   2.22       317465   AW197361   Hs. 131360   ESTs   2.22       332458   M33493   Hs. 184504   tryptase; alpha   2.22       333195           CH22_FGENES.98_17   2.22       304837   AA587139       EST singleton (not in UniGene) with exon   2.22       307602   AI288843   Hs. 231239   EST   2.22       337078           CH22_FGENES.457-1   2.22       335862           CH22_FGENES.629_7   2.22       301979   L28168   Hs. 121495   potassium voltage-gated channel; lsk-rel   2.22       335668           CH22_FGENES.590_19   2.22       305068   AA639618       EST singleton (not in UniGene) with exon   2.21       329034           CH.X_hs gi|5868561   2.21       318403   AI131241   Hs. 143234   ESTs   2.21       328058           CH.06_hs gi|5902482   2.21       335513           CH22_FGENES.571_28   2.21       330803   AA004699   Hs. 150580   putative translation initiation factor   2.21       331427   H54764   Hs. 237339   EST   2.21       338973           CH22_DJ32I10.GENSCAN.27-6   2.2       336723           CH22_FGENES.85-3   2.2       327290           CH.01_hs gi|5867483   2.2       337240           CH22_FGENES.644-1   2.2       306201   AA926818       EST singleton (not in UniGene) with exon   2.2       303659   AA868464   Hs. 126263   ESTs; Highly similar to FIBRILLARIN [H.s   2.2       334517           CH22_FGENES.399_7   2.2       334189           CH22_FGENES.352_4   2.2       335199           CH22_FGENES.508_8   2.2       333705           CH22_FGENES.250_19   2.2       305794   AA845324       EST singleton (not in UniGene) with exon   2.2       303273   AA316069       EST cluster (not in UniGene) with exon h   2.2       313384   W85694   Hs. 118335   ESTs   2.2       329158           CH.X_hs gi|5868687   2.2       337551           CH22_FGENES.847-8   2.2       328792           CH.07_hs gi|5868309   2.2       303737   AW502711       EST cluster (not in UniGene) with exon h   2.19       324529   AW502466       EST cluster (not in UniGene)   2.19       323103   Z45529   Hs. 92030   ESTs   2.19       333773           CH22_FGENES.272_4   2.19       337906           CH22_EM: AC005500.GENSCAN.56-19   2.19       327129           CH.21_hs gi|6531976   2.19       305710   AA826544       EST singleton (not in UniGene) with exon   2.19       335595           CH22_FGENES.581_34   2.19       323646   AA310926   Hs. 154412   ESTs   2.19       328368           CH.07_hs gi|5868388   2.19       325802           CH.14_hs gi|6552451   2.19       337167           CH22_FGENES.562-27   2.19       305059   AA635756       EST singleton (not in UniGene) with exon   2.18       321445   AW245524   Hs. 121590   ESTs; Weakly similar to ZINC FINGER PROT   2.18       332790           CH22_FGENES.2_4   2.18       336750           CH22_FGENES.128-4   2.18       310999   AI520706   Hs. 171012   ESTs   2.18       329798           CH.14_p2 gi|6523160   2.18       327012           CH.21_hs gi|5867664   2.18       304599   AA506638       EST singleton (not in UniGene) with exon   2.18       335351           CH22_FGENES.539_4   2.18       310661   AI354717   Hs. 223908   ESTs   2.18       332791           CH22_FGENES.3_1   2.17       333022           CH22_FGENES.65_1   2.17       310502   AI458973   Hs. 170422   ESTs   2.17       324963   AA853440       EST cluster (not in UniGene)   2.17       325275           CH.11_hs gi|5866902   2.17       328338           CH.07_hs gi|5868377   2.17       333063           CH22_FGENES.75_6   2.17       308895   AI858423       EST singleton (not in UniGene) with exon   2.17       338685           CH22_EM: AC005500.GENSCAN.472-4   2.16       325655           CH.14_hs gi|5867007   2.16       332420   H49570   Hs. 108074   ESTs; Weakly similar to CEREBELLIN 1 PRE   2.16       337216           CH22_FGENES.613-10   2.16       335660           CH22_FGENES.590_11   2.16       337145           CH22_FGENES.542-2   2.16       335753           CH22_FGENES.604_2   2.16       301766   R02224       EST cluster (not in UniGene) with exon h   2.16       303442   AI953998   Hs. 152510   ESTs; Weakly similar to L-SERINE DEHYDRA   2.16       311009   AI949701   Hs. 210589   ESTs   2.16       307093   AI167606       EST singleton (not in UniGene) with exon   2.16       300262   AI874402   Hs. 170810   ESTs   2.16       337989           CH22_EM: AC005500.GENSCAN.112-7   2.16       326263           CH.17_hs gi|5867264   2.16       319402   W21298       EST cluster (not in UniGene)   2.16       321010   Y17456   Hs. 227150     Homo sapiens  LSFR2 gene; last exon   2.16       301706   AI929150   Hs. 241496   ESTs   2.16       307412   AI241753   Hs. 241507   ribosomal protein S6   2.16       335662           CH22_FGENES.590_13   2.15       332480   AA092932   Hs. 12570   tubulin-specific chaperone d   2.15       329273           CH.X_hs gi|5868762   2.15       339383           CH22_BA232E17.GENSCAN.3-20   2.15       332795           CH22_FGENES.5_1   2.15       335227           CH22_FGENES.513_13   2.15       326925           CH.21_hs gi|6456782   2.15       332403   AA424199   Hs. 106529   ESTs; Highly similar to CGI-65 protein [   2.15       317786   AI859605   Hs. 155686   ESTs   2.15       326582           CH.19_hs gi|5867318   2.15       336494           CH22_FGENES.832_11   2.15       329656           CH.14_p2 gi|6448516   2.15       307581   AI284415       EST singleton (not in UniGene) with exon   2.15       335670           CH22_FGENES.591_2   2.14       332452   AA040369   Hs. 11170   SYT interacting protein   2.14       309387   AW079943   Hs. 156110   Immunoglobulin kappa variable 1D-8   2.14       308427   AI652677   Hs. 195055   EST   2.14       322027   NM_004551       EST cluster (not in UniGene)   2.14       301693   Z45023       EST cluster (not in UniGene) with exon h   2.14       334308           CH22_FGENES.373_11   2.14       301131   AW134518   Hs. 131807   ESTs   2.13       338495           CH22_EM: AC005500.GENSCAN.387-1   2.13       329600           CH.10_p2 gi|3962481   2.13       307980   AI431696       EST singleton (not in UniGene) with exon   2.13       337260           CH22_FGENES.652-15   2.13       304655   AA527887       EST singleton (not in UniGene) with exon   2.13       303141   AF195951       EST cluster (not in UniGene) with exon h   2.13       327957           CH.06_hs gi|5868210   2.13       334317           CH22_FGENES.374_1   2.13       302870   AF011407       EST cluster (not in UniGene) with exon h   2.13       333806           CH22_FGENES.278_2   2.13       329947           CH.16_p2 gi|5540101   2.13       309602   AW182523       EST singleton (not in UniGene) with exon   2.13       322790   AI700273   Hs. 122162   ESTs; Weakly similar to KIAA0557 protein   2.13       337706           CH22_EM: AC000097.GENSCAN.87-11   2.13       306894   AI092731       EST singleton (not in UniGene) with exon   2.13       325530           CH.12_hs gi|6525289   2.12       321087   AL110227   Hs. 241533     Homo sapiens  mRNA; cDNA DKFZp434J194 (fr   2.12       309853   AW298169   Hs. 57553   tousled-like kinase 2   2.12       326822           CH.20_hs gi|6117831   2.12       328776           CH.07_hs gi|5868309   2.12       335112           CH22_FGENES.494_20   2.12       334564           CH22_FGENES.405_4   2.12       333455           CH22_FGENES.157_4   2.12       317395   R55044   Hs. 124130   ESTs   2.12       334221           CH22_FGENES.360_1   2.12       331374   AA442134   Hs. 70573   ESTs; Weakly similar to HINT PROTEIN [H.   2.12       304473   AA428343   Hs. 140   immunoglobulin gamma 3 (Gm marker)   2.12       328907           CH.08_hs gi|5868493   2.12       319448   R05539   Hs. 108738   ESTs   2.12       333676           CH22_FGENES.247_3   2.12       324767   AA630931   Hs. 34348     Homo sapiens  mRNA; cDNA DKFZp434P0235 (f   2.12       318585   Z43405       EST cluster (not in UniGene)   2.12       331732   AA251192   Hs. 177708   ESTs   2.12       329553           CH.10_p2 gi|3962492   2.12       336910           CH22_FGENES.343-6   2.12       326959           CH.21_hs gi|6469836   2.12       305417   AA725228       EST singleton (not in UniGene) with exon   2.11       301573   AI150328   Hs. 226402   ESTs; Weakly similar to mitochondrial ci   2.11       326935           CH.21_hs gi|6004446   2.11       335176           CH22_FGENES.504_6   2.11       337210           CH22_FGENES.603-5   2.11       311284   AW027025   Hs. 239262   ESTs   2.11       330240           CH.05_p2 gi|6671858   2.11       327463           CH.02_hs gi|6004455   2.11       332938           CH22_FGENES.41_3   2.11       332785           CH22_FGENES.1_1   2.11       301035   AI358105   Hs. 123164   ESTs   2.1       305712   AA826701       EST singleton (not in UniGene) with exon   2.1       318651   AW003150   Hs. 240165   ESTs   2.1       302753   M74299       EST cluster (not in UniGene) with exon h   2.1       334635           CH22_FGENES.417_2   2.1       319447   AA456745       EST cluster (not in UniGene)   2.1       301204   AW008544   Hs. 239994   ESTs   2.1       333950           CH22_FGENES.303_6   2.1       325947           CH.16_hs gi|5867138   2.1       337683           CH22_EM: AC000097.GENSCAN.76-1   2.1       328962           CH.08_hs gi|6456775   2.1       336655           CH22_FGENES.34-3   2.1       336596           CH22_FGENES.163_2   2.1       330486   M13755   Hs. 833   interferon-stimulated protein; 15 kDa   2.1       314356   AA531607   Hs. 125143   ESTs   2.09       314976   AA524725   Hs. 162108   ESTs   2.09       336650           CH22_FGENES.29-6   2.09       339026           CH22_DA59H18.GENSCAN.22-6   2.09       302395   AW297357   Hs. 114606   ESTs   2.09       323280   AI910263       EST cluster (not in UniGene)   2.09       338857           CH22_DJ32I10.GENSCAN.1-1   2.09       335374           CH22_FGENES.543_12   2.09       308766   AI808510       EST singleton (not in UniGene) with exon   2.09       331027   N48584   Hs. 6168   KIAA0703 gene product   2.09       337853           CH22_EM: AC005500.GENSCAN.37-1   2.09       302498   NM_002991       EST cluster (not in UniGene) with exon h   2.09       312607   AI337440   Hs. 169375   ESTs   2.09       314309   Z44049   Hs. 184352   ESTs; Weakly similar to cDNA EST EMBL: D3   2.09       311695   AI142078   Hs. 135562   ESTs   2.09       333280           CH22_FGENES.126_2   2.09       333518           CH22_FGENES.173_3   2.09       337199           CH22_FGENES.583-11   2.09       337819           CH22_EM: AC005500.GENSCAN.13-9   2.08       300546   AA214450   Hs. 250913   ESTs   2.08       322577   AA354452   Hs. 59075   ESTs; Weakly similar to WD40 protein Cia   2.08       336028           CH22_FGENES.672_1   2.08       300238   AI394673   Hs. 254030   ESTs   2.08       307429   AI243573       EST singleton (not in UniGene) with exon   2.08       326444           CH.19_hs gi|5867385   2.08       310641   AI345597   Hs. 254727   ESTs   2.08       337633           CH22_C20H12.GENSCAN.32-1   2.08       336008           CH22_FGENES.668_6   2.08       339030           CH22_DA59H18.GENSCAN.24-1   2.08       333952           CH22_FGENES.303_8   2.08       329149           CH.X_hs gi|5868685   2.08       335192           CH22_FGENES.507_7   2.08       308225   AI557713   Hs. 177592   ribosomal protein; large; P1   2.08       330519   M94172   Hs. 69949   calcium channel; voltage-dependent; L ty   2.08       331809   AA402482   Hs. 97312   ESTs   2.07       324837   AJ003669   Hs. 246171   ESTs   2.07       332608   D00749   Hs. 36972   CD7 antigen (p41)   2.07       327291           CH.01_hs gi|5867483   2.07       315936   AW069807   Hs. 247094   ESTs; Moderately similar to !!!! ALU SUB   2.07       317917   AI143593   Hs. 129419   ESTs   2.07       328674           CH.07_hs gi|5868254   2.07       338654           CH22_EM: AC005500.GENSCAN.460-55   2.07       320828   AJ012590   Hs. 194728   hexose-6-phosphate dehydrogenase (glucos   2.07       337896           CH22_EM: AC005500.GENSCAN.56-3   2.07       335310           CH22_FGENES.532_3   2.07       300076   AW074835   Hs. 145223   ESTs   2.07       303588   AL046182       EST cluster (not in UniGene) with exon h   2.07       328848           CH.07_hs gi|6381921   2.07       318723   C18060       EST cluster (not in UniGene)   2.07       335352           CH22_FGENES.539_5   2.07       339316           CH22_BA354I12.GENSCAN.22-15   2.06       335873           CH22_FGENES.631_1   2.06       335261           CH22_FGENES.520_2   2.06       322032   AL079807       EST cluster (not in UniGene)   2.06       308771   AI809301       EST singleton (not in UniGene) with exon   2.06       310024   AI252661   Hs. 145224   ESTs   2.06       320555   R36212   Hs. 235534   ESTs   2.06       319314   T74062       EST cluster (not in UniGene)   2.06       334642           CH22_FGENES.417_9   2.06       335767           CH22_FGENES.607_1   2.06       336159           CH22_FGENES.707_3   2.06       336358           CH22_FGENES.818_1   2.06       334687           CH22_FGENES.419_12   2.06       339389           CH22_BA232E17.GENSCAN.4-7   2.06       335898           CH22_FGENES.635_6   2.06       328847           CH.07_hs gi|6381920   2.06       313431   W91884       EST cluster (not in UniGene)   2.06       313270   AI374993   Hs. 159611   ESTs   2.06       339211           CH22_FF113D11.GENSCAN.6-6   2.06       333860           CH22_FGENES.290_19   2.06       308952   AI868157   Hs. 224226   EST   2.06       305471   AA743947       EST singleton (not in UniGene) with exon   2.06       300619   AA991438   Hs. 233293   ESTs   2.06       302962   AI693349   Hs. 228981   EST   2.06       332446   AA112799   Hs. 238756   ESTs; Weakly similar to unknown [H.sapie   2.06       334972           CH22_FGENES.468_2   2.05       330196           CH.05_p2 gi|6165140   2.05       304754   AA579795       EST singleton (not in UniGene) with exon   2.05       309726   AW248521   Hs. 195188   glyceraldehyde-3-phosphate dehydrogenase   2.05       333939           CH22_FGENES.301_5   2.05       304836   AA587008       EST singleton (not in UniGene) with exon   2.05       302087   AA324163       EST cluster (not in UniGene) with exon h   2.05       308424   AI650714       EST singleton (not in UniGene) with exon   2.05       304347   AA176914       EST singleton (not in UniGene) with exon   2.05       333141           CH22_FGENES.85._1   2.05       310573   AW292180   Hs. 156142   ESTs   2.05       337565           CH22_C65E1.GENSCAN.1-11   2.05       304295   AA084082       EST singleton (not in UniGene) with exon   2.05       326624           CH.20_hs gi|5867553   2.05       326443           CH.19_hs gi|5867385   2.04       339012           CH22_DA59H18.GENSCAN.19-2   2.04       337384           CH22_FGENES.745-1   2.04       332326   T79623   Hs. 111787   ESTs   2.04       303706   AW501525       EST cluster (not in UniGene) with exon h   2.04       336046           CH22_FGENES.679_8   2.04       301770   R05887       EST cluster (not in UniGene) with exon h   2.04       326726           CH.20_hs gi|5867597   2.04       330485   M11186   Hs. 113216   oxytocin; prepro-(neurophysin I)   2.04       332956           CH22_FGENES.48_13   2.04       300021   M97935       AFFX control: STAT1   2.04       306872   AI086920       EST singleton (not in UniGene) with exon   2.03       302744   L03151       EST cluster (not in UniGene) with exon h   2.03       338507           CH22_EM: AC005500.GENSCAN.390-11   2.03       334020           CH22_FGENES.317_1   2.03       333870           CH22_FGENES.291_3   2.03       330552   U40223   Hs. 248157   pyrimidinergic receptor P2Y; G-protein c   2.03       335486           CH22_FGENES.570_18   2.03       339374           CH22_BA232E17.GENSCAN.2-5   2.03       328384           CH.07_hs gi|5868392   2.03       334690           CH22_FGENES.420_3   2.03       310318   AI733942   Hs. 145338   ESTs   2.03       325893           CH.16_hs gi|5867088   2.03       331373   AA435513   Hs. 178170   ESTs; Weakly similar to DUAL SPECIFICITY   2.03       329784           CH.14_p2 gi|5912597   2.03       335087           CH22_FGENES.488_11   2.03       310582   AI336563   Hs. 254585   ESTs   2.03       332611   R06751   Hs. 1600   chaperonin containing TCP1; subunit 5 (e   2.03       339258           CH22_BA354I12.GENSCAN.8-3   2.03       336851           CH22_FGENES.274-1   2.03       305596   AA780664   Hs. 8734   ESTs; Moderately similar to !!!! ALU CLA   2.03       330364           CH.X_p2 gi|3126882   2.03       302940   AL137619       EST cluster (not in UniGene) with exon h   2.03       317349   AA923657   Hs. 126359   ESTs; Weakly similar to !!!! ALU SUBFAMI   2.03       309869   AW300314       EST singleton (not in UniGene) with exon   2.03       333422           CH22_FGENES.147_2   2.03       325233           CH.10_hs gi|6381943   2.03       330586   U77968   Hs. 79564   neuronal PAS domain protein 1   2.03       336725           CH22_FGENES.88-1   2.02       334157           CH22_FGENES.340_7   2.02       303357   AW006352   Hs. 159643   ESTs; Weakly similar to MLD [ H. sapiens ]   2.02       328533           CH.07_hs gi|5868482   2.02       309210   AI962817       EST singleton (not in UniGene) with exon   2.02       327412           CH.02_hs gi|5867750   2.02       333172           CH22_FGENES.94_7   2.02       334869           CH22_FGENES.447_3   2.02       301047   AA971465   Hs. 116136   ESTs   2.02       329394           CH.X_hs gi|6478817   2.02       301736   F12128       EST cluster (not in UniGene) with exon h   2.02       335591           CH22_FGENES.581_30   2.02       338234           CH22_EM: AC005500.GENSCAN.260-7   2.02       334433           CH22_FGENES.385_8   2.02       334904           CH22_FGENES.452_18   2.02       318443   AI939323   Hs. 157714   ESTs; Weakly similar to NEUR ACETYLCHOLI   2.02       300151   AI243445   Hs. 189654   ESTs   2.01       310348   AI478563   Hs. 145519   ESTs   2.01       310898   AI439868   Hs. 165742   ESTs   2.01       332860           CH22_FGENES.27_3   2.01       301699   AI879117       EST cluster (not in UniGene) with exon h   2.01       332554   W96450   Hs. 23111   phenylalanine-tRNA synthetase-like   2.01       327994           CH.06_hs gi|5868218   2.01       315613   AW137420   Hs. 192311   ESTs   2.01       335356           CH22_FGENES.541_3   2.01       334028           CH22_FGENES.318_7   2.01       335277           CH22_FGENES.523_3   2.01       308657   AI749855   Hs. 236497   EST; Weakly similar to GLANDULAR KALLIKR   2.01       305913   AA876109       EST singleton (not in UniGene) with exon   2.01       323681   AW247730   Hs. 102548   glucocorticoid receptor DNA binding fact   2.01       333533           CH22_FGENES.175_20   2.01       328753           CH.07_hs gi|5868298   2.01       302397   L01694   Hs. 211523   guanine nucleotide binding protein (G pr   2.01       304643   AA526588       EST singleton (not in UniGene) with exon   2.01       333065           CH22_FGENES.75_8   2.01       316192   AA904441   Hs. 221286   ESTs   2       302533   L36149   Hs. 248116   chemokine (C motif) XC receptor 1   2       312988   AA813689   Hs. 123436   ESTs   2       333612           CH22_FGENES.217_7   2       333615           CH22_FGENES.217_10   2       316085   AI027959   Hs. 132300   ESTs   2       337936           CH22_EM: AC005500.GENSCAN.85-7   2       330972   H18467   Hs. 118983   ESTs; Weakly similar to diaphanous 1 [H.   2                                                    
     [0346]               TABLE 20                          B survivor vs Mets - Up in Mets                                 Pkey   Ex Accn   UniG_ID   Complete Title   Ratio BS/Met                                         316625   AA780307   Hs. 122156   ESTs   0.28       316076   AW297895   Hs. 116424   ESTs   0.3       315943   AA699756   Hs. 117335   ESTs   0.38       317198   AI810384   Hs. 128025   ESTs   0.38       320082   AA487678   Hs. 189738   ESTs   0.39       313510   AI147291   Hs. 154006   ESTs   0.39       323683   AI380045   Hs. 225033   ESTs   0.39       318558   AW402677   Hs. 90372   ESTs   0.4       310264   AI915771   Hs. 148867   ESTs   0.4       314945   AW276866   Hs. 192715   ESTs   0.41       313403   W86995   Hs. 113157   ESTs   0.42       321505   H73183   Hs. 129885   ESTs   0.43       312171   AW444619   Hs. 138211   ESTs   0.43       324585   AI823969   Hs. 132678   ESTs   0.44       316695   AA809844       EST cluster   0.44                   (not in UniGene)       319818   AA825819   Hs. 136952   ESTs   0.44       337522           CH22 —     0.45                   FGENES.819-1       324714   AA574312   Hs. 245737   ESTs   0.45       315060   AA551104   Hs. 189048   ESTs   0.46       300548   AI026836   Hs. 114689   ESTs   0.47       304483   AA431441       EST singleton   0.47                   (not in UniGene)                   with exon       313096   AI422367   Hs. 163533   ESTs   0.47       306501   AA987294       EST singleton   0.47                   (not in UniGene)                   with exon       329086           CH.X_hs   0.47                   gi|5868604       320176   AA167566   Hs. 133325   ESTs   0.47       320418   AI674461   Hs. 199638   ESTs   0.47       302982   W92391   Hs. 198222   ESTs;   0.48                   Weakly similar                   to C2H2-type                   zinc f       315609   AW207535   Hs. 224012   ESTs   0.48       317056   AA904908   Hs. 250643   ESTs   0.48       314361   AL038765   Hs. 161304   ESTs   0.49       315169   AI371390   Hs. 158667   ESTs   0.49       323743   AA324992   Hs. 257168   ESTs   0.49       313903   AW167439   Hs. 190651   ESTs   0.49       315061   AA551196   Hs. 188952   ESTs   0.49       300969   AI140799   Hs. 76230   ribosomal   0.5                   protein S10       331950   AA454595   Hs. 99369   ESTs   0.5       315076   AI623817   Hs. 168457   ESTs   0.5       300975   AI283548   Hs. 149668   ESTs   0.5                                                    
     [0347]                       TABLE 1-20A                       Pkey   CAT Number   Accesssion                  108446   112224_1   AA085383 AA126091 AA074174 AA075373 AA079120 AA070831 AA075978 AA075372 AA128503       108474   116896_1   AA115179 AA079667 AA115897 AA079771       100635   10605_34   BE259039 W29128 AW410299 X72990 BE246492 NM_005243 X66899 AI909006 AW248151 AL031186 AA012966 BE273549 BE311429               BE253102 Y07848 BE538102 BE256863 BE261240 BE312156 BE618412 BE257322 BE620446 AW806629               AA376777 AA325384 BE256808 BE251039 BE257878 BE275352 AA357169 AW403562 AA204995 AA093259 W95953               BE256279 BE336683 BE252465 BE251266 AA380754 BE294942 AA380941 AA380999 BE297164 BE249995 BE294719               BE295372 AI270673 BE305132 BE563752 BE295357 AI525421 BE263980 AA057505 AA020915 BE266318 BE206948               AI474020 BE296420 BE297374 BE408545 BE019366 BE407372 BE266180 BE279437 R58233 T19567 BE300738 AW381179               AA357571 AW361285 AA436908 AA301019 AA301022 N20202 BE408777 BE548638 BE167415 AA071260 BE088429 BE280092               W23117 T19568 R51681 AW402216 W22784 BE185607 AI457224 BE544120 AL134874 S72620 AA375079 D51319               AW818280 BE514686 AW853024 BE563744 AA300469 T07592 BE622190 BE272834 W21781 BE315450 BE542367 BE393120               AA988441 H55137 BE562296 BE622502 BE395960 AA329733 AA332348 AI768317 AA456866 AI497832 AW878437 AA857042 U18018               BE621418 AI818790 AI949507 BE397693 AI885545 AI858854 AI355147 BE169028 S62138 AW732191 AA856891               BE266060 X71427 BE268557 AF095890 AW001288 AI799634 AI623498 AA071346 BE547662 BE261446 AI564543 BE559759               U35622 BE314249 BE264915 AI638591 AI538385 AW090025 BE384754 AI888689 AW778800 AI925273 AA075797 AW949130 AV660275               AW438697 AI587137 AI524121 AA806249 AW628247 AA808241 AI244388 AI761125 AW117672 AA911782               AI129250 AA654447 H55291 BE258050 BE206162 W95867 AA857187 AI871378 AI660103 AW103827 AI220929 AW149949 BE465561               AI302857 AW168841 D82190 AW249814 AI623432 AI687358 AW951077 R51592 W60458 AI092863 AW474693               D12765 AI911646 D82208 D82187 AW074031 AI358527 AW338497 AA970893 AW072573 AA205364 AI858886 AA012830 AW148763               AI863056 AA548656 BE250325 AI016994 AI864005 BE046122 AI497746 C75340 R58896 D82141 AW168240               C19048 AI741090 D29465 AI222365 AA948288 AI583522 AW572212 AI091290 AA582727 AA579897 AA570629 W60883               AW516989 AL038160 AA577334 AI865872 AA994043 AA922583 AA464778 AA209178 AI829479 AI370235 BE246529               AA384177 AA456255 AI699730 W60654 AL035744 AA862042 R32756 AI886886 AA993087 AI289479 AA627840 AA464184               AI619503 R32755 AW075358 AI432315 AA457024 AA020865 R92132 AA454629 AA746059 AA454643 AA456240 AA826984               BE163738 AI806470 AI991074 AI802560 AA587095 AA558714 AA968521 N87780 AI538246 N71794 AV661738 AI368903               AA362570 AI989445 AI674962 S75762 BE245204 AA975296 D20123 AW005704 AA693328 AA582270 AI918474 AW205707               AI696299 AA220990 AA101538 T29030 H27201 AW262526 AI610530 AA126840 AA126790 X92120 AW367868 BE299644               BE299451 AA476561 BE300044 AA134363 BE295222 AA307504 N42337 AA319098 N39502 AW964461 N57241 BE299049               N86332 R51156 AA085859 T75212 AA133939 AA147129 AA156161 BE543953 BE538848 AA133676 BE299745 AA135050 AA218535 AW406401               AW411287 BE410528 C01410 NM_004083 BE314959 AA836413 AA085862 AW024370 AA471059               AW467508 AA001025 AI828231 AA633221 T95517 AA147038 AA476447 AW027012 AW078627 BE513200 AI192297               AA886279 AW081806 AA316185 AA010506 AI269929 W93139 AI682935 AA609555 AA378028 AI093877 AA999997 AA730698               AI143923 AW575315 AA890550 AA494353 AW576601 AI796336 AA826130 AA609207 AI539618 AI088539 AI089090 AA825505               AA632978 AA015892 AW204713 AA156495 AA824613 AA133630 N29826 AA527476 AI633352 T27908 AA134364 AA133940               AW043601 H37775 AA772375 AA057871 AA047888 AA054225 H86568 AA001511 H25718 AW189507 AA165589 AA054433               H85549 AA165486 AA058972 AA454911 AA464064 AA493802 AA428253 R85508 AW302469 AI611812 BE162582 F11073               T95518 N26811 AI783929 H40669 AW611745 AI658803 R51042 R45276 AA528386 AA782875 AW880218 AL138391 AA314536               AW949338 AA149466 AA149552 AI346513 AA216776 BE349131 AW007654 AI141803 AA622688 AI185131 AW057635               AA101539 AA627986 H27202 AI536847 W93084 AI973148 AI246788 AW572108 AI469414 AA454835 AA612707 AA430746               AI084991 AA010400 AA856636 AA463928 AI248310 R07170 AA834033 D12244 AI655670 AA054350 AA639480 AI702067               AI475389               100643   3931_1   NM_005032 M34427 AA332167 AW409711 AL119718 BE297581 BE299855 AA082284 AA226855 AA149568 AW391953               M22299 BE163594 AW847881 AW366993 BE142871 AW847885 AW604137 AW847753 AW847886 AW376442 U48350               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W60009 AA044283 AA121161 AI539277               AA301885 AW019944 AA133445 AA101108 AA033559 W70060 AA617751 AI986261 AI023234 D82235 AA085846 AW754181 D82093 D82100               AA147653 AA600256 D57884 AI753982 AI568050 AI146490 AW302280 AI433051 AA329188 AW572150               AW166345 AI337981 AA778973 N67577 AA227207 AA838281 C06190 AL046997 AI217662 AI752979 AW627538 AI127171               AI440461 T64184 AA845190 AA227111 AA877394 R60962 AA505646 AA770545 AI696264 AA953747 AA904094 AA058318               D57026 T17158 AA578545 AW085082 BE148939 AW815069 BE152843 BE149068 BE149036 AW815073 AW753691 BE149040               AW815065 BE152842 BE149072 AW753692 AW815055 BE152837 BE152849 BE152840 AW815070 BE152829 BE152846               BE148972 BE149042 BE149074 AW753668 BE152832 BE152841 BE149082 BE149050 AA347261 BE152852 BE152847               R65797 F02189 AA483448 AI954410 AA865375 BE152836 BE152838 BE152839 T17300 BE152844 BE152833 BE152834               AA029542 AI567601 AI362353 BE162140 AI381384 BE152851 D57038 D57043 AI418363 AA133478 BE149051 BE149083               BE152850 BE149052 BE149084 AA886686 BE149064 BE149032 AA044093 AA129934 AA303976 BE157211 AA187291               BE152830 AA046552 BE149047 BE149079 BE149033 BE149065 BE149044 BE149076 BE149053 BE149085 BE149034 BE149066 BE149048               BE149080 BE149038 BE149070 BE149045 BE149077       100670   22023_1   AA332178 BE259177 BE545625 T09105 S62076 M16424 NM_000520 BE244309 F13516 BE251567 BE514981 AL119537               AA336739 BE261801 AA278642 N32708 T77034 W24621 W42478 AW630382 AW856214 AA134234 M13520 BE379212               AA287459 BE019379 BE297192 BE162970 AW405668 AW403322 BE272280 BE208703 BE304428 BE162807 BE162828               BE162887 BE078944 BE163025 BE162878 BE162909 BE162898 BE162791 BE162880 BE073563 BE163086 BE162896               BE162770 BE073565 BE162906 BE162913 BE162947 BE162803 BE262199 BE162811 BE080697 BE315095 AW206024               AI291054 BE087364 AL046839 AA304422 AA847660 AA669876 BE392765 AI567798 AW026644 AW151258 AA996314               AI828660 AI571158 T61941 AW103503 AW172698 AI923115 AI823709 T62167 AW771381 AW151782 AI799284 AW242271               AA128031 BE261306 BE312241 AI674880 BE261057 AA630684 AA831305 AI139546 AW082447 AA916854 AA916855 T05970               AA599395 AA921680 AI244674 AI041920 AA424998 AI362999 W42543 T51260 AI362486 AI699366 AI827925 AI027381               AI027370 AI209049 AA782220 AI334014 AI279051 AI217711 AI674210 AI193370 AI701683 T23782 AI927545 AI784291               AA128007 AI370630 AI972736 AA853763 N92379 AI916746 AA639633 AA907603 AI479452 AW950971 T28985 AI685825               AA563654 AA745291 AW089417 F10858 AI354227 R38108 AI668647 AA994088 AI740910 AW880973 AI739410 AI480346 N78987 AI473892               BE162903 BE254430 BE260426 AA650012 AW006426       100673   21517_2   AW403342 AW248986 BE561709 AA357312 BE311834 BE389496 BE294887 AW732696 BE047868 AI702383 BE019155               AI702367 BE408966 BE280458 BE313759 BE513492 BE535404 BE280258 AC005263 NM_007165 L21990 AW732711               AI564920 AW249094 BE265365 AW607186 AW607346 BE005217 H27211 U46230 BE260066 BE207043 BE546782 AW248659       108559   41469_9   AA085228 AA085161       108569   118606_1   AA082885 AA114265 AA085398 AA113184       100700   17137_1   AA932794 BE540417 AW409802 AW410765 BE296651 BE294197 BE164813 AW381886 AW381806 AL048654 AW403058               BE207228 AA464654 AW966967 AA326831 BE407277 BE408669 AA476527 AA115576 AA359697 AA476357 AA449939               BE263719 AL045304 W21442 R28919 BE395990 AA252273 AI346812 BE538487 AA507160 W93950 N42025 AI088439               AL134931 AA031524 AI887287 AW470017 AA476423 AA464553 AW410766 AI569421 AA577476 AI248935 AI912371               AW615674 AA824237 AA807746 AA827377 AA890268 AA476309 AI086424 AW409698 AA031553 AW451901 AI520934               AW050554 R49825 N30302 AA532541 W94004 N93402 AA115549 AA331202 L25665 NM_005275 AA436745 AI122671 R49779               R18508               100734   35197_1   AI807481 AI500404 AI092260 BE348962 AI143675 AA772399 AA772398 AI368565 AI379172 AI083781 AI871363 AA843793               NM_000141 M87770 X52832 M55614 Z71929 W05259 AA548551 AI498743 BE081295 BE162251 F05643 AI127918 H83199               W07463 BE551725 R28404 AW206461 AW590506 AI885536 N69800 R93496 R25381 AA443093 AI143063 AI284647 AI703144               AA309032 AA309031 AW949426 AW949428 AI638387 AI638356 R77173 R38513 T89263 F01900 H87979 R70205 AA664355               AA235910 AA033657 AI436212 N50463 AI433805 AI081876 AI421090 AW020818 AI559529 AI887420 BE154202 AA889062               AA723410 BE537575 AA236812 AI218552 AI264866 AI290617 AA424365 AA424505 AW073347 AA032183 AI142488 N55322               AI884363 AI336070 N67307 AA608928 T94993 AW514184 AA724695 N66630 AI379638 AI274671 AW628470 AA235346               AA687581 AI073906 AI263602 AI869111 AI805693 AI423808 AI076491 AI374640 H82967 AA776567 AA256191 T29856               AA953586 AI140801 AI805484 AA984329 R93497 AI017114 AI263355 N81103 AW418776 D57474 AI918460 AA256152               AI683268 AI042628 AW196650 C00195 AI918567 T28903 N95383 R13671 T94939 AI275235 AA235751 T84335       100739   2738_3   M59287 L29222 AI251890 BE244986 AI708332       117040   46956_1   AW970600 AA503323 H89218 AF086031 H89112       100748   41861_1   X06096 X05826       100760   1334_7   AW794626 M27126 M27014       100779   458_127   BE561958 BE561728 BE397612 BE514391 BE269037 BE514207 BE562381 BE514256 BE514403 BE514250 BE397832               BE269598 BE559865 BE396881 BE560031 BE514199 BE560037 BE560454       100787   458_127   BE561958 BE561728 BE397612 BE514391 BE269037 BE514207 BE562381 BE514256 BE514403 BE514250 BE397832               BE269598 BE559865 BE396881 BE560031 BE514199 BE560037 BE560454       130872   21268_1   U61084 NM_904900 U61083 AI761325 AI826909 H79385 T81886 AI222763 N68038 AI281048 H79274 AA603662 AA721720               T71211 C00488 AA994672 AW136970 AW368715 AA380767 AL022318       108641   853_−13   AA112059       100818   19604_3   U79251 AA843851 R38201 R66461 R44908 AA683289 H17477 R37364 R52832 AW298336 AA351391 NM_002545 L34774               AA296886 AW967001 T28889 R13451 T77331 AL119196 AL118830 H08459 AW892812 AW905838 H17585 R52878       130930   2773_1   NK_005658 U19261 BE622108 AA313592 AW950162 H25107 R71725 R50630 AI524201 AI476301 AW014547 AW195770               AI378122 AI554908 AI927196 AI913959 AW044513 R50534 AI379950 AI311593 BE043305 R82981 AA769375 R77429               AW196220 AI269033 AA883433 R71691 F11489 AW771234 AA402642 AA399408 AW771244 AI400707 R55446       124394   5590_5   AI950447 AW027427 AI640151 AI139433 AI400708 AW779975 AI739122 AI384000 AW079410 AI473425 AA150109 AI766579               AI351784 AI209046 AI474732 N29724 AI382653       100882   458_127   BE561958 BE561728 BE397612 BE514391 BE269037 BE514207 BE562381 BE514256 BE514403 BE514250 BE397832               BE269598 BE559865 BE396881 BE560031 BE514199 BE560037 BE560454       100885   12707_3   X07881 NM_006249 X07637 AA376715 AA376677 X07715 X07704 S80916       100896   205_6   M91803 X65362       100898   8542_1   BE387614 R51501 AA199714 AW674779 F08178 BE269071 AA376313 H08264 AA380420 H18785 AL042151 BE277758               BE267438 NM_005850 L35013 BE540833 BE390902 BE391494 BE277459 BE385592 BE390612 BE384263 BE387779               BE388647 BE537373 BE547158 AW409585 AW374033 AW602185 AA355725 AW577548 AW935015 AW935160 W40232               AW938647 AW374332 AA434040 BE293488 AL138361 BE560260 AI745075 AA317980 AW949382 AI834311 AI653582               AI831042 AI361878 AA618606 AA729052 AI424969 AA199715 AW769374 AI828422 AW044307 AI862816 AI203583 AW084461               AW514655 AA831883 AA290672 AA831286 AA578510 AW089965 AW150746 AA292743 H22232 AI469275 AW439312               AA292744 AW471443 AI473989 AA593336 AA464070 AI678937 AW069451 AA970763 AA610480 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AA477649 H13898 AI056086 H42356 R32267 R99431 AA481898 AI130779 AA769777 AA910293               AI284079 AA936692 AA903953 AA947753 AI568924 AA902966 AA807082 AA489337 N58247 AA872223 AA485362 AA024906               AI092224 AA443621 AA603059 N58248 AA927262 AA329524 AA026369 N73450 AI244031 AI192676 N25190 W32248 W32324               AI284307 AA074470 N33116 AA947399 H52855 T52343 AA643260 AA573752 AI031889 AA877690 AA531409 X13710               AI500538 R32315 BE168562 AA401993 AA883251 W37615 AA305694 W78964 AA024905 H53678 W47278 AA224423               AA371881 AA335679 AA336008 T52416 H69646 AA300266 AA325728 N73204 N77626 R54691 W24032 AA868340 BE407766               H81968 W46665 AA883934 AA187290 AW571425 AI280505 AI079662 AI470373 AA991617 AA173165 AI244032 AA922440               AA856918 W80458 AA121251 AI160062 H50349 T67744 W46574 AA969287 W01485 BE615302 BE388184 AA314246 H85693               W31948 AV650437 AW160467 W44891 AA723773 AW328531 AA313224 AA299527 R86894 AA312505 H21582 AA157493               H78480 N36060 N77627 BE218674 W02853 AW954844 AA429974 BE382847 AI541225 H93229 BE281553 AA147790               AA327374 AW839840 AA969229 R99337 BE278812 AI190450 AA479549 AA156012 R78705 AA224081 N44944 D56066               AA969012 AW178878 AW105500 N52391 AA622301 AA858204 AI290372 AI205676 H51289 AA548013 BE544240 AA280160               BE170901 AI192429 R77056 AA310925 AI219128 AA121993 AA070432 R63012       108785   4962_−6   AA128946       102156   33676_1   H08948 AA353935 R14985 U17977 H15387 F05567 R88476 AW968314 R89646 R87941 AA258917 AW895155 AW947450               AA223175 AA223559 W92508 W02327 AA322882 AW960879 H39040 H39039 R90891 AA580343 BE155037 BE154984 N40110               AL137683 BE265131 R17329 AL096733 M79202 AA625234 AA427472 AW361296 AA658045 AA322177 R54596 AA171880               AL042331 U18920 AA298036 AW051888 AI378803 AW601640 AI885103 AA297019 AI192706 AW055183 BE312004 H42382               AA534726 AA205943 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AW591711 AI354982 R49145 AI360724 AI458656 AW304052 Z41443 AI864783 AW651615 AI270639 AW316592               R43741 AA482068 R72852 AW190442 AW651631 AW470902 AA911918 AW779251 R72820 AA279995 AI394715 AW105688               AI097434 AA670473 F08806 AA035597 AW008688 AI689117 AI911859 BE387696 AW166880 AA847278 W78016 AI886548               N35512 T86152       125077   1814028_1   T88822 T80794       124440   22853_1   AA532519 AA770627 BE326342 AW073299 AW205539 Z83851 AA725380 AI457288 AA976882 BE220181 AA988940 AI914073               N46435       100941   3303_2   U15422 NM_005425 X63758 X63759 Z46940 L03378 AI220577 AA634325 AI381479 AA994994 AA994988 AA416961       117286   558874_1   AI188710 AI032142 AW078833 N30308 AW675632 AI219028 AI341201 N22181 H95390       117291   1047256_1   N81189 AW172914 N22182 N22289       132316   10556_2   U28831 AA088359 N56023 AA069486 AL038872 AI683185 AA632516 AI281643 AA447146 AI699884 AI281642 AA832250               AI909017 AA781851 BE090060 AA058888 AI440090 AA040563 AA069449 AI702237 AA045495 AA088258 AA229820 AI925213               AA928183 N90591 AW794070 AI884470 AA219147 AI632560 AA553416 T10311               102295   26281_1   AB007881 U32581 AW131202 AW995994 W31964 N24261 AI033045 H98694 AW364848 AI222031 AA907216 AI215730               AA776981 AW473826 W31373       132380   166896_2   AW373665 AW373648 AW373647 AW393531 AA284401 AA253299 BE168092 AA196249 AA810695 AA278353 AI806177               BE552269 AW001862 AA749299 AA253300 W37080 AA805586 H72533 AI698623 AA292703 AA748852 H75291 H68018               AA883728 N48304 N49030 BE168089       102337   553_1   AI814863 AA806761 AA765241 AA019317 AA092255 AA035405 T85079 AA890151 AI373959 T85080 BE153728 AA740848               BE080682 AL048137 AW182316 AI699488 AW274481 AW407538 AA306562 AW950024 AW949943 AL045703 AW843196               W25132 BE612794 AA304266 AW958054 H25673 AV646563 AV648573 BE172990 AW593488 AA385181 AA164998 AI246476               AA345406 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AW467069 AA809346 AI188507 AI494178 AA872752               AI631631 U02310 NM_002015 AA815006 AI382453 AW197658 AI761654 AI804396 AI382221 AI813640 AI439635 AI523901               AW517242 AI221705 AW298104 AW204560 AW573095 AW028783 AW014650 AI766744 AI808294 AI698758 AI041809               AI766667 AI479103 AA872797 AA769305 AA765080 AA334166 AI472322       131862   3673_14   AI541246 AW055046 BE312897 NM_006623 AF006043 AL038012 BE256739 BE272577 AA143633 AA143643 BE464595               AI312112 H01791 R26319 BE170902 AW131612 F29120 AA455866 AI540181 AI885777 F36716 AI149501 AI246028 AI373003               AL046700 AA455869 W69120 AA146617 AI188256 AI937281 AI806751 AI087240 AI123219 AI589686 AI332501 W69087               AI494321 AA725793 AI222350 AA625736 AA644568 AI472282 AI370905 AA934652 AA913035 AI128576 AW341709 AI269125               AA975139 AI620890 AI969828 AI356660 W95879 F32252 AI218442 AI928601 AI474470 AI245409 AI601111 AA928594               AI809316 F19498 AI373442 AI218893 AA573914 AA906869 AI833041 AA993899 AW250763 AA887142 AA884655 R26108               AI919414 H01042 AA534622 AA723368 AW005753 AI871394 AA661885 BE171317 BE271194 AW249310 T83902 BE246962               BE279817 BE562094 BE513363 AL045369 BE561008 BE267526 BE544065 BE559579 BE561747 T35796 BE250596 BE268704               T31298 BE536521 BE561183 BE269560 BE269944 BE514005 BE561068 BE268145 BE267559 BE559744 BE560930 BE278335               BE513832 BE561017 BE396371 BE562260 BE281009 BE281327 AW410446 BE259628 BE547443 BE311971 T83809               AW249441 BE270204 BE295488 R90868 BE269359 BE397222 BE396694 AW248394 BE397708 BE268174 AW247676               AW248404 AA093721 BE397622 AA093706 T09027 BE408338 BE261454 BE260628 BE295110 AF171237 BE295135               BE407534 BE536635 BE264727 BE296052 BE270265 BE546712 BE298269 BE547732 BE548734 BE253463 BE312238               BE261042 BE545186 BE313055 BE542602 BE538530 BE535215 BE208107 BE513616 BE295982 BE561273 BE560057      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AI435786 AA683040 AI907872 AW369725 AA380303 AA836230 AW419434 AW501816 AW502342               AW502333 AW499671 AW502991 AW501843 BE168376 AW501486 BE245921 AW372603 AW372604 AW372601 AW372608               AW372609 AW372612 AW372607 AW753096 AI902532 AI902594 AI902533 BE062377 AW811106 X97301 AA315458               AL041463 AA287787 BE544417 BE311801 AW797378 AI940181 AA326261 AA326712 AW964943 AW751304 AW751303               AI940199 AI940192 AI940189 AW751305 AI940167 AW176500 AI940202 AI940190 AI940201 AI940196 AI940203 AI940210               AI940193 AI940177 AI940179 AI940204 AI940171 AW382746 AW382738 AW751312 AI940753 AW062939 AW803210               BE175400 BE175388 BE094921 F28478 BE066456 AW372263 BE066575 BE066320 AW372262 BE066580 BE066455               AW576937 AW392415 BE183395 AA381175 BE388469 BE066460 BE066315 AA377951 AA171585 AW605004 AW605007               AW934766 AW934869 AW580606 AW605280 AW834728 R83817 AL121069 R20109 AA291361 AA524293 AW374653 H30144         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AA894924 AI912962 AA569977 AI675362 AI473131 BE046814 AW300260               T31879 AW168376 AI659621 AI810463 F35064 AI271700 AI699563 AA776537 T36184 AA565451 AI678338 AW438921 R16094               N91497 AV662182 AI432919 AA910303 N91964 F18684 AA381902 AW364462 AI276689 AB015644 AW247214 BE047724               AA347210 BE391395 H81815 N67777 BE208123 AW939117 AW939167 AW939108 AW939172 AW939123 AW939158               AW605520 AW605509 AW605515 AW939122 AW939171 AA229095 AA229096 AA229232 BE382710 AI902544 M78278               AW799890 AW889685 AW863018               103436   42952_1   X98206 AA693431 AA244304       102806   8441_2   AI246240 AF124733 NM_016358 U90306 BE407995 BE281254 AI566193 AI652266 AI671516 AI950190       103491   36109_1   AF264750 AA904457 AW884708 BE183627 Y08478 AW962945 AA305849 Y08479 BE255205 BE258400 Y08468 AB040939               T05961 AW807004 AW062952 AA135076 AW997220 AA090128 AW137099 AI640514 AW592676 H01987 AA134913 AA599219               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N54724 W01777 AI949662 AA917338 N50068 AI857652 BE550711 AI340079 N63025 AA971513 AI467976               AI694919 BE328279 AW206626 AI310369 AI307346 AA425773 AI862813 AA628674 AW475016 H10786 AI932791 AA244420               AI567886 AA621126 AA244453 AA369087 AI678489       127008   175968_1   AA223753 AA223879       127027   41793_1   AL390088 BE207034 Z42964 BE242833 AW583731 BE616399 BE621126 BE272661 BE561537 AW328160 BE513636               AW732368 AA367575 AA317809 AA325684 AL043346 AW997819 BE207681 AA442690 N33908 AA329967 AV661996               AA364929 AA132857 R41876 W30718 AA340232 AA923628 BE618790 BE383719 BE384891 AW973886 AI680631 AL042633               AL044048 T64995 AI814372 AA046927 AA707444 AI351042 AW157778 AW303835 AA559116 AW157476 AW440951 AI146410               AI570583 AW473765 AA931145 AI654587 AI089717 AA132763 AI199778 AI144493 AW473769 AW087749 BE166742 AI089476               AW083264 BE206437 BE222620 AW615413 AI356436 H98622 AI674887 AW583314 AI081960 AA133159 AI932568 AA641830               AW245125 AA543056 AI289158 AI538987 N67489 AW836308 AI042462 AA639343 AA706144 AA653493 AI363727 AA724790               AA596032 BE277184 AI126007 AI241020 AW627956 AW440961 N30676 AI806651 AA583594 AA732028 AA731516 AI439229               AW995619 AA133204 AW248060 AI914553 AI689519 AI521043 AI566390 AI245111 AA594407 AI797417 AA131580 AA035240               T33853 AI362604 AA535337 AI273040 R68453 AA043655 AI587360 AW572022 AA935227 AI697259 AA749181 BE263051               R68454 BE560435 BE277826 Z49985 U30174 D61707 BE390825 BE618267 U30173 D61706 Z49984 BE268853 N99057               AI874052 AA568135 R68452 H21498 AA043654 AA046984 AA362959 AA035318 R17261 AA131629 BE166750 BE298260               N25142       127036   1150_2   AI468598 AA232868 AL043752 AW881016 AW881015 AW881214 AW880761 AW881018 AA255767       103513   42559_1   Y10209 AW341910       127041   1534405_1   Z43067 F12549 F06090 R11929 T74454 R12925       126406   95703_1   N76683 AA034096 AA034082       127064   1690305_1   T84214 Z43709 R05654       133660   27207_1   H14843 C14857 F06523 AA322683 AW964649 H83334 AW894647 AW894608 AW578353 BE007437 AW894648 AW894609               AW896993 AW897085 AW581270 R36029 AL117536 AW896412 AW993019 AW859782 AW859772 AW376619 BE082963               AW376687 H24066 AW847946 AA091541 D51576 D52043 D52146 D51628 D52155 D51675 D51777 D52101 D51602 D51843               D51878 D51751 D51820 AA319632 AA351569 AW630840 BE073033 D51985 AW838560 AW838633 AW838631 AW838554               AW838557 AW838559 AW608175 AW608194 AW838558 AW838562 AW838564 AW838571 AW608170 AI926544 AW608177               AA296774 AW838624 AA318941 AA319199 AW960724 BE073078 AA773508 AI925495 AI889128 AI633207 BE221497               AI126062 AI344458 AW608176 AW838627 AW194765 AW838630 H24379 T23982 R62391 BE620113 W02397 R87373               AA364488 AW963466 AI696793 AA012998 N72571 C18550 AI298061 AI084648 D51984 C14379 D52154 T03606 AI499301               AA017178 AA017170 BE077301 AI889566 AI002790 AI205010 AW104793 AA298374 AI049720 D51575 D52042 D51627               AI281148 AW104111 AI142928 D51601 D51842 D51819 D53690 AI242974 AL049247 AL036365 AL036366 D45664       102934   16110_−11   X13451       126479   1297811_1   T78141 T75126 AW953462 AW956923 T08967               125877   18687_2   AW969436 AK000755 AA176076 BE258269       103650   43833_1   H16443 T66760 H11411 Z70220 F12208 T66258 AW950931 AA350846 H06005 F12617 N51174 T74154 R87613 T33928               Z45881 AW961235 T31307 AW891440 H24171 R18227 R19098 W26891       127191   206872_1   AA625286 AA297581 AA303053 AA303052       103682   41323_1   AF275815 AA018302 AA000993 AA021290 H86017 R69197 AA056286 R88858 AI570404 H43774 AA059385 AA010839               AA056237 AI436578 AI769179 AA019840 H86715 H84086 AA000994 H85881 AI762043 AI079265 AI738426 AI654986 AI738440               AW197623 AA021232 AW161646       126568   163056_1   AW749469 W68106 BE162986 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AA442429 T19477       126759   109907_1   AA063089 AA679118 AA063642       126762   110350_1   AA064613 AA064671       126767   327401_1   AW968865 AA491199 C17148       112309   1576900_1   R55021 H26613       128099   501940_1   AA905327 AI148973       127452   327502_1   AA504447 AA491317       126808   121207_1   AA662559 AA086320       126844   133298_1   AW881997 AA121637 AA299325       103985   19574_1   AB032251 AW852071 AA279887 AW852124 AW129468 AI583544 AA704421 AW999851 BE081960 AW390494 AW582002               AI862331 AA700432 AI186130 AI720707 AA236286 AI336961 AW015054 N91172 AI698141 W32818 AW896124 AI701519               AW894048 H87416 AA234040 W17142 R84565 AI803033 AW867682 H27242 AA366224 AA357157 H86935 BE090270               AW753846 AW362772 BE464864 AA704907 AA704948 AA704938 H27235 AI033427 AW850923 AA480900 AW502989               AW851237 AW851374 BE252815 AA084307 AA313880 AW961200 AA480961 AF114105 AF114103 AA486042 AW375963               AW752365 AW375959 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  171173_1   AA210697 AW962138 AA309665 AA210819       126982   171753_1   AA211419 AA211566       113195   178688_1   H83265 T63524 AA304359 AW960551 AI672874 AI749427 AA227777 AW027055 AA971834 T49644 T54122 AI983239               AI808233 T91264 T96544 AI350945 AI709114 R72382 T48788 R48726 AW385418 AI095484 T49645 AA928653 AA570082               AW007545 T57178 AA516413 AA913118 T57112 AA564433 AA774503 AA367671 T59757       128260   38164_1   AF119848 AI132994 AA505575 AI307657 AW205687 AW291922 AI347642 AI308117 AA398902 AA741579 AW269612 R72857               AW418818 T23611 AI016388 AA641630 AW009309 AI078310 AW263980 AI971867 Z32873 R00068 AW028860 R57097               AA402507 AW965254 AA114126 AA331445 AA333324       128279   1561282_1   H18818 H08885       113213   23798_1   NM_001395 Y08302 AI434019 AI470328 AI261807 AW024965 AI806537 AI830549 AI640337 AI219065 AW271700 AW028488               AI133339 AI859205 R51175 U87167 BE379324 BE392008 AA340819 AA343110 T57275 D59164 AW299312 AI434422               AI936390 AW024975 R40262 AW269126 R09430 T56590 AI367247 AI253132 BE464248 T58658 AW207785 T58607       120461   22556_18   AA810830 AA251301 AW962926 AW962922 AW962925 AA371510 AW817535 AW817579 AA251629 AW837817       127705   966283_2   AJ003322 AJ003324       127787   458957_1   AA809310 AW975709       112746   93768_1   AA541537 AW009489 AW950203 F25552 AA834645 N56270 AA029543 AI633587 F30948 C04983 AI628613 AA885458 T49449               F13651 AW004753 AA369573 AA356955 AA355112 T49448 AA918022 AI910358 H40428 AI292038 AI684655 AI244426               AA522725 AA352551 AA909796 AA494329 AA873880 AW957305 AW955082 AA552169 AA974888 AA977363 R93237               AI865725 AI201852 AI244721 H40429 AI204631 AA029544 AI015353 AI245274 AI191342 AA662656 AA829667 AW001837               AA626833 AA585220 AA522987 AI339186       128410   288073_1   AA424107 AA452788       128440   210591_1   AW090340 R52194 T87269 R17095 T91445 N76763 R82785 AW512315 AA534961 AW002002 H41133 AI985800 AI278720               AI762576 AI798477 AW081499 AA314880 AI918168 W92216 T91358 T79785 F04683 AI824664 T78491 AA302483 AW958008               T85160 T87183 R11236 R16208 F01406 AW150480 AW627337 T79354       127854   443883_1   AW976796 AA769520       120606   39874_1   AF169690 F08337 AA282956 AA282955       120734   208882_1   AA299948 AA299949       105897   8177_1   H03573 AA310766 AL133603 AI700910 H00505 R82804 H60605 T10498 BE176241 N99617 BE537165 AA443413 H02733               AI267539 AA094718 AI299771 N50199 R64087 AA709363 R26971 AI962859 H03899 H03888 R63010 AI346026 AA328951               AI025251 H89260 AI472009 AW029442 AA211594 AI310418 AI913561 AW515607 AW593597 AI926843 AW073920 AW002745               R62957 AI439422 AA401091 H58246 R82805 AI174264 AI590100 AW510481 R26739 H02624       100097   17246_13   AF002224 AA017358 AL119785 AI379446 AI632616       106782   83684_1   AW054886 R48313 AI200750 AI358095 H28124 AW613845 AA010033 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AW291409 AI377801 AI049681 AA767458 AA053631 AW473092 AW079490 N48698 R38875 AW501274               AI817699 AA847277 AA761843 T07221 AA873077 AA568215 T51538 AI474852 AW505117 N50751               100403   19804_1   AA302974 AW952936 AA297841 T17453 AL040862 AL042305 R18514 Z45908 H09477 R51937 H02949 AW672666 AA339081               AW024007 AI910124 R41507 R02276 W72600 AW606045 T30584 AI968122 AA532894 AA047712 AA024602 AI814501               AI479333 H09478 AI801077 R63410 AI469769 R63363 AA731181 W67437 AA613000 AA125822 W60322 AI199934 AI032499               AI673744 AW675418 AA594241 AA047679 AI148807 AA948543 AI805752 AI362640 AA883795 AI873413 AW292015 BE503009               AA960821 AI302435 AA911051 AI192308 T31342 AW589705 T32492 AW384043 AI968407 BE501316 AA074832 AI611662               AI969799 AI216685 AL117466 NM_016733 D85527 AW992053 Z44073 BE078508 R70709 AL046533 AA402079 AA125952               AA337799 BE252284 BE253079 AA325230 C18518 W67436 T83901 AA353025 AA024601 BE068484 AA782927 AA401915               AA369003 R53606 W76565 AL040863 W60241 AI967950 AI424849 AI582302 AI769611 AI394573 AI949294 AI656190 AI885933               AA670336 BE465592 T17452 AI569505 AA075098 Z41532 T35104 AI699545 R02275 AA368470       100476   24092_2   NM_001907 X71877 X71874 BE140276 AA748397 AA213801 AA830996 AA765114 AW874469 AA811623 AA844904 AI371956               AW451919       108360   112653_1   AA129037 AA071539 AA071460 AA129036       108390   112416_1   AA121999 AA121985 AA071108 AA071116 AA071434 AA148869 AA075070 AA122000 AA121986 AA071117 AA071109               AA148655 AA075232       108392   113549_1   AA075124 AA075208       100534   20653_36   T85231 AW161503 AW401856 BE397508 BE387085 BE514425 BE387606 BE391894 BE562022 BE561561 BE537755               AA326129 BE397421 T49865 BE259375 BE562435 AA206146 BE272379 AA206012 BE252021 BE264415 BE559498 BE622499               BE560425 AF141349 AF070600 BE260687 BE267430 BE273769 BE409463 BE378506 BE410826 BE540360 BE514334               BE265991 BE259493 BE257982 BE541302 BE275305 BE249816 BE263407 AA306533 BE312339 BE537252 BE313173               N44590 BE397957 BE314066 AF070593 AF070561 BE395620 BE539980 BE278635 BE622457 BE561276 BE561240 BE539757               BE398025 BE539587 BE264804 BE312816 BE618175 BE312236 BE536880 BE275163 BE409064 BE268157 BE256878               BE396565 AA094095 BE512689 BE539943 BE613640 BE561500 BE314652 BE560895 BE270780 BE394023 BE314771               BE258043 BE545484 BE539560 AI524946 BE268922 BE313646 R21491 BE257007 J00314 T55776 BE514288 AA079759               V00599 AA090885 BE268939 AI424151 BE393150 BE513223 BE311978 AA427899 Z36874 BE267470 BE270600 BE270542               AA092574 BE513746 T56664 BE260686 BE561863 T80533 BE614348 AI003020 AA196886 BE395929 BE256732 T80512               BE561248 H10806 N23553 AA090625 BE378633 BE299481 BE251134 F03598 BE158989 BE271056 BE271117 H39974               BE537728 T95426 T93847 R15283 T82017 BE561756 BE254463 BE250916 AA522520 BE562294 BE561853 BE562013               BE410876 R17504 BE254605 BE254904 BE315454 BE408837 BE256847 BE259444 BE265709 BE395378 AW869359               BE019791 BE378840 BE270975 AW246214 AA352945 AA378509 BE275472 BE389534 AI609281 BE295688 AI972188               BE388702 AW351598 BE617054 AI922439 BE258416 AL119346 AW351963 AW351971 BE388178 AI624652 AA780798               BE268311 R35263 BE251613 AW366022 AW177828 AW057797 AW366021 AW177888 AW366065 BE140945 AA670139               AA773017 BE539636 BE139520 BE270946 AW058238 AA191567 BE312975 AW089641 BE398147 BE268285 AW272598               AL119339 AW079784 AI829482 AI982828 AI862019 AI816169 AI633046 N59068 AW731944 AA093100 H03237 AW575087               BE301207 AW780181 BE141633 AW664164 AA626909 AW516663 AW872823 AA551910 AW571502 AI954158 AA548713               AA599912 AA301057 AW574903 AA614152 AA613830 AW771103 AA706556 AI023390 AA551248 AA780901 AA633446               AW419192 AA404660 W58436 AA523401 AA578734 AW615710 T65580 T57191 AA486211 AA604684 BE208800 AA669875               AA622085 BE302083 BE263081 AA548072 AW156997 AI568868 AI627575 AA565217 AI870317 AI282474 AA704034 AI253598               BE328271 AA564664 AA161128 AA604105 AA609087 AW103504 AA605238 AA704108 AI221585 AW574515 AW117994               AA058521 AA604281 BE251293 BE017988 AI754462 AW245235 BE094031 AW862436 AW105529 BE544089 AW303918               AW130826 AI721132 AA433888 AL038189 AW474816 AW182745 AA551345 AI445794 AA398452 AI224993 AI689213               AW249709 H15542 AW196813 AA618551 AI445281 AI638121 AA807410 AA911530 AI334093 BE269844 AA847782 AW276513               AW589524 T03418 AW170654 AW468976 AA570676 AA570715 H41474 AA010074 AA600283 AI755222 AI193239 AA774176               AW770036 AI332603 AI129785 AI280055 AA666338 AW732127 AW028394 AA102641 AI920834 AA602712 H06697 AI095237               AA401908 AW250765 AA631796 AA550854 BE260391 BE614352 AI690333 AA452272 AW575264 AA878265 AA190483               AI832049 AA195830 BE439812 BE208085 AA826727 AI929438 H10785 AI520704 AI364235 AA605138 AA513116 AI250046               BE263592 BE538689 AA171900 T03755 AW241170 AA565529 AA186883 AA872245 AI251930 BE538023 AA181759 AA187178               H28109 AA115169 AA513309 BE545993 AA714730 AW897950 AA143782 T15562 T49475 AA196794 AA219637 AW574805               R61459 BE294610 AA653641 AW246595 AA122178 AA079030 BE259347 AA125802 AA223509 AA071105 AA056515               AA115965 H98828 AA975764 R44928 AA122173 AW499013 W68765 AI306457 H70716 AI866327 AA101102 AA523008               AI567597 AA146744 R88666 AA197332 AI086825 AA197306 AA127186 AA648686 AI758939 H66791 AA158684 AI423641               BE622207 H96899 AW748838 AI683391 T57141 AI360649 AA084328 AA205369 AA605035 AA730337 AA190782 AA622674               H70715 AL035929 R53569 BE410471 AA826991 BE304945 T57181 AA190793 AI826886 R61544 AA357249 AA730680               AA349636 AA598937 AW075466 W52142 AI270583 AA693372 D53633 T78875 AI874190 AI926336 AI744448 AA458786               AW019919 AI903107 AA243188 AA127188 AA085973 R50969 AW674943 AW674933 N33158 T99016 AA386238 H05817               AA227228 T93797 BE408530 AL035916 AA199872 AA196440 T61038 AI193541 T03458 H04813 T26581 AW074308 F28259               AI420254 AW406597 AI752919 AA349540 AI961511 AI026726 T16511 T61589 AI872394 AW069694 AA350697 AI766468               N84462 AA085828 AI049703 F09606 AW247712 T16319 T95336 AA427580 AA219549 N54075 BE383804 AI934238 T23636               T23966 AI540707 AA852250 AA480844 F03543 AI682148 AW029145 AA350647 T57116 AA121780 AA362506 T89452 F03033               BE544518 BE537982 AI400848 AW249805 R40175 BE547154 AW194658 BE304905 F03972 AI887116 AW662060 N64153               AW090474 AA111861 BE544487 AW247971 AW189742 AA083676 AI689361 AI865447 AA205201 AA995389 T57070 AI749217               AA620398 AI205275 BE278095 W25238 AW498851 AA361225 W24643 BE293452 T60878 BE378902 AW675067 AW419249               BE546138 BE622685 H37989 BE298837 W02581 W03143 W03350 BE090146 D56472 AA477356 AA369046 BE617569               AW405756 BE068241 H94917 R93689 BE536003 H78709 BE293724 BE207577 AA324949 AW406102 R66280 AW404427               AW498515 AA283600 BE091536 N78168 N94034 H13896 H40383 AA426247 H38210 AW381001 AW381031 AW384779               AI187246 AA356920 BE614174 AA361144 AA954817 AA373947 N51059 AA714393 AA361010 AA858368 AA128860 AA186577               R97861 BE300605 BE617658 AW407835 AA007136 W04495 AA714521 W01702 AW675093 AI129627 W23528 BE622513               D52760 AA580710 D54714 D54912 H39979 AI189140 AA604554 AA379346 AA379753 BE293739 AI247952 H19587 H23957               H22624 AA022986 H80389 H80376 W32684 H74304 W73673 BE619989 H46803 AA326012 BE256750 BE293868 AI687073               BE540791 AI554627 AI669399 AI052649 N74381 BE254994 W35343 R83888 AW405482 BE300603 AA190680 AW409945               AI565178 Z25891 H95714 AI587135 AW881291 N74433 AW580801 AI126014 AW583313 AW385805 BE392285 AI002971               R85251 AA928186 AW883103 AW577705 N47822 AW245647 AI186441 AA455487 AA876464 AA512933 R48210 AA167661               AA715724 T56604 BE315352 R25751 BE163471 W77978 AA617822 AA618045 AW973348 AA641395 N32598 N58159               AA604336 AA617894 AA748311 AA599921 AA617899 H94863 AA029390 AA706656 AA206124 AA778101 BE300604 T15728               W57648 AW575696 AA029389 AA599861 AA640585 AA613863 AA526077 AA577614 AW575035 BE183827 AI709081               BE183680 AA330412 AA580149 AW574766 AI609157 AA557458 AI801804 AW085646 AW339731 AA907669 AA489663               AA486665 AW166938 AI500319 AA181843 AA605173 AA486566 W94458 AI623349 AA858195 AA558201 AI249662 AI092843               AA905720 AI682690 AA773433 AA434385 AA022948 AI249681 AI619676 AI084530 AA554408 AI376770 W35304 AW574722               AA279871 AA641309 W00970 AA564566 AA206053 AI682641 AI686270 AA216784 AI371057 BE208021 AI816060 AA977763               AA988221 W56716 R66281 T60692 AI371108 AW316667 AW090548 AW263786 AI688536 BE300865 AW118162 AW089606               AW157567 AW439435 AW673929 AW027607 AW474885 AI984259 AW571884 AI880916 AA758525 AA070410 AW190306               AW246746 BE221650 AI630670 H28485 AW468627 AW651608 AA360204 AW513778 AI608753 BE302410 AI750057               AW674261 AW510365 W94350 AA761293 AI869840 AA301790 AA933607 AA227144 AA716677 AA181762 R83889 AI079599               AI000208 N99897 AA070466 AW245167 W68620 N83377 AI361698 AA464157 AA496711 AA205826 AI361699 H80288 R50934               H98743 AA179708 D52483 AW249546 T49476 H80293 W73625 AA099853 H03238 AA179703 AI880803 AA653206 AA457733               AA931701 AA190330 AA906004 H79483 AI084626 T57243 AA079760 T55734 AA507899 W73915 T74565 AA523607 N69544               R97811 AA190385 R86252 AI359329 AA157496 AA070716 AW162385 AI929421 AW651618 AW087897 AW770466 AW073321               AI813809 AA113799 AI342925 AI754395 W60153 AA665490 AA653483 AW087840 AW169380 AI754330 AA181774 AW243958               R76858 AA936814 AA477111 H80279 AA496723 AA633000 AA243218 AW169688 H80274 R48211 AA743251 AI221630               AW593584 H40328 W56761 H95640 R93010 AW250165 AA497004 AA279793 W20432 AA775006 AA401150 T34421 T29637               AA678773 W23704 AA723093 AW073071 AI140379 AI188662 AA680074 AI081730 AW874489 AA226908 AI452689 AA531164               AW498837 AA670295 AI061112 D20132 AI937246 AA580593 N70277 AW993170 AA205918 AA581651 AA129695 AA548261               AW673898 AI000118 C13991 BE247777 AA653439 AI198072 R26594 AA282708 C14467 C14444 AI000629 C14510 AA775369               AA885560 F30063 D51934 D51834 D51478 D51931 D52011 D51918 D52160 D52045 D51888 AW245330 D52030 AA936639               D51494 D52144 D51448 D52138 D51730 AI419648 D52007 AW021403 AA935494 AA935487 AW770291 AI702431 AA687083               AA362527 D51696 R29267 AA653197 AA888552 D54444 C15448 AA478045 AI589903 D55942 H40340 AI864969 AI341782               AA353097 AW439647 AW305322 N54940 AA935976 AW248042 AI783806 BE349217 AA969923 AA383726 AA357323               AA007135 AI915436 N71185 AI123662 AA328354 AA331419 N21981 T03306 D54551 AA983808 D54942 D55074 AA113880               D52740 AW020376 AW020367 AA936029 AA555005 AA969180 AW812036 BE544746 N89212               100544   22955_11   M55405 AW752552       100545   22955_11   M55405 AW752552       124087   1561179_1   H08773 R37687       100560   30266_1   Z99916 U71216 NM_004076 X15144 X15145 X15146 AA652300       100571   7592_1   L14561 AW496834 AW059849 Z99413 T29666 R14900 R93603 R51525 S49852 U15687 U15686 AI033177 W94597 AI056839               R02057 AA134349 F05567 H73767 BE326691 AI984023 AI695688 AI750184 AI434336 AW029158 AI440089 BE046108 R51526               R53074 AA025218 AW083388 R93604 AA732638 H47642 AI859270 R41222 AA593057 AA760815 H43399 N29456 AI337321               H98205 AI752749 AA442913 AW961129 AL134557 AW439527 AI341304 AW190061 AW613371 AW439931 AA806627               AA781883 W05800 AA731599 AI863791 AI370277 Z38623 AI470448 H15877 R53656 D82513 D82467 D82386 D82515 R15295               AA096386 AW892808 AA300686 AW954282 AW959453 H29807 R25259 N46722 N46679 D60314 AA736829 Z99414 AI076802               AW576457 H16400 AA933075 AI752748 N75064 AW873040 N39235 AI310710 BE328592 N39576 AI672714 AA747547               AW769967 AI625462 AW169755 AW615361 R53545 AI758375 R46612 AW273091 AA736697 H29808 R42200 D14108               AI783809 AI270395 AA952981 AA746745 R37023 C75654 Z39578 C75656 AW956278 AA338702 AA338701 AA279433 W58753               AA041264 R02056 AW842224 AI215415 AW951238 AW022139 AA658234 AL119699 BE537020 AI795941 AA927068 AI765979               AV655427 AA041498 AI436090 AI190267 AA397563 H43344 AI718564 AW192067 BE328781 AW768573 AI358433 AW631373               AA262804 AW235152 AI570253 AA934641 AA776029 AW182028 AA279606 AV657690 AV657727 AV657350 N41480 AI926218               T29285 BE143058 N72769 AA385114       100572   13049_1   M60495 M60499 M60500 M24355 M62201 BE389102 M96943 L01090       100582   26433_2   D13897 AI183955 NM_004160 D13899 L25648 AW136574 AI654355 AA913288       108409   113869_1   AA075631 AA075578       100627   tigr_HT2798   Z25424       123526   genbank_AA608657   AA608657       100663   tigr_HT3059   M20022 M32505 M32506 M32507 M32508 X64880 X87678 X87680       100684   tigr_HT3283   S66933 U15688       100687   tigr_HT3291   L18862       100695   tigr_HT315   M31126 M38243 M74197 M94890 U04323 U08196 U08197       116389   genbank_AA599011   AA599011       100702   tigr_HT3413   L27065       100756   tigr_HT3768   M88357       100809   tigr_HT4261   L33990       100810   tigr_HT4262   L33994       100854   tigr_HT4464   U08607       102185   entrez_U20230   U20230       125090   genbank_T91518   T91518       100961   entrez_J00148   J00148       102254   entrez_U28131   U28131       125145   NOT_FOUND_entrez_W38001   W38001       125153   NOT_FOUND_entrez_W38294   W38294       116797   genbank_H40486   H40486       102354   entrez_U38268   U38268       102474   entrez_U49973   U49973       116902   genbank_H70739   H70739       116905   genbank_H71420   H71420       102643   entrez_U67849   U67849       125576   205199_1   R21635 R66208       118579   genbank_N68905   N68905       120256   genbank_AA169801   AA169801       120274   genbank_AA177051   AA177051       113149   genbank_T51588   T51588       127759   808057_1   AI369384 AA719568       113518   5697_40   AW367788 AI093217 AA533602 AI300430 AI860318 AI869201 AA933015 AA077695 AA649045 AI016319 AW084216 AI969650               AW169170 AI440341 AI744376 AA905125 AA194528 AA971323 AW510721 AA194483 AA076744 AW182167 AI955513               AA578875 T89731 T89829 AA828731               113608   genbank_T93113   T93113       101046   entrez_K01160   K01160       122731   genbank_AA457549   AA457549       108316   genbank_AA070160   AA070160       108328   genbank_AA070204   AA070204       108394   482708_1   AA642953 AA075144 AA084113 AA070130       108395   482708_1   AA642953 AA075144 AA084113 AA070130       108417   483241_1   AA070853 AA075749 AA075716       108436   genbank_AA078801   AA078801       108491   genbank_AA082973   AA082973       108499   genbank_AA083103   AA083103       122922   genbank_AA476268   AA476268       122938   genbank_AA477119   AA477119       122948   genbank_AA477483   AA477483       117046   genbank_H89505   H89505       101427   entrez_M19508   M19508       101559   entrez_M32053   M32053       117437   genbank_N27645   N27645       101798   entrez_M85220   M85220       117590   genbank_N34904   N34904       110349   genbank_H40988   H40988       101909   entrez_S69265   S69265       103392   entrez_X94563   X94563       119053   genbank_R11501   R11501       103457   entrez_X99728   X99728       119174   genbank_R71234   R71234       119229   genbank_T03229   T03229       103654   entrez_Z70759   Z70759       103679   entrez_Z86000   Z86000       119329   genbank_T51832   T51832       119343   genbank_T62873   T62873       119347   genbank_T64349   T64349       119523   NOT_FOUND_entrez_W38041   W38041       119526   NOT_FOUND_entrez_W38049   W38049       119529   NOT_FOUND_entrez_W38053   W38053       119564   NOT_FOUND_entrez_W38206   W38206       119566   NOT_FOUND_entrez_W38209   W38209       126908   533102_1   AA180024 AA169866       119906   genbank_W85818   W85818       123022   genbank_AA480909   AA480909       114604   485245_1   AA075966 AA076128 AA128755 AA128339       114666   genbank_AA112274   AA112274       100221   entrez_D28383   D28383       123143   genbank_AA487595   AA487595       114718   480609_1   AA080912 AA075318 AA083403 AA078992 AA076594 AA062835 AA084926 AA081881 AA082953 AA113913 AA083821               AA070343 AA134801 AA113892 AA075419 AA063293 AA071252 AA078900 AA113888 AA071406 AA075072 AA100879               AA112153 AA062836 AA113865 AA074554 AA643251 AA084110 AA078783 AA084346 AA078993 AA079022 AA079776               AA070181 AA085031 AA082954 AA082971 AA131328 AA063179 AA083366               100478   tigr_HT1067   M22406       100547   tigr_HT2219   M57417       100563   tigr_HT2324   Z11585       100564   tigr_HT2324   Z11585       123473   genbank_AA599143   AA599143       123490   genbank_AA599723   AA599723       322024   43541_1   AA334384 AL137436 AA352089 AW341247 BE327629 AI669284 AI274156 AI123562       322033   33332_1   AL137507 AW879790 AA349971 AI624899 AW294742 AW271762 T06484 AA788895 R35098       314251   194954_1   BE011657 AA713589 AI440513 AA278620       320825   29807_1   NM_004751 AF102542 AW380893 AF038650 BE304708 AW360892 AW360931 AW842622 AA307800 BE292814               AW582119 AW582122 AW374998 AW374874 AI587061 AA583339 AW662377 AW192901 AW887756 AW887761 AI955582 AI150400 AA568218               AA583146 AI832775 AA294856 AI445680       320832   170589_1   AA214584 D56572 D57294 AA207006 AA210987 AA601292       320882   41486_1   AK000655 AW024515 AI499162 AI673527 AA903900 AW084419 AI219549 D60890 AW243134 AI832098 AI811630 BE348831               AI022831 AI475320       322128   46785_2   R95860 AF085903 R95859 AI346033       322135   46801_1   AF075082 H48639       322141   46810_1   AF075092 H53478 H53853       322152   78409_4   BE614761 AA263136 W00335 W00327       321525   27440_1   AJ006077 AA377082 H78875 AA263148 AW958548 AA381830 AA381631 AW748909 H47990 AW402973 R31722 R82733               AW195851 AI650977 AI635744 AW136376 AI913496 AI569147 AW263050 AW075972 AI538882 AI762430 AI924045 AW613027               R74454 AI638560 AI476181 AA873030 AA936769 AI862049 AI955522 H00589 R31680 C20629 AI799176 AA835126 AA310578               H13126 AI858430 AA377081 BE244193 AF288208 W26453 AV659072 AF288209 BE622910       320913   24943_3   AA663733 D62598 D62472       321583   87512_1   AA018518 AA059305       320957   39063_1   AF151534 AI929478 W40378 H17557 AW163309 BE074271 AW854041 AW604408 AW853903 AA206576 AA133144               AW854378 BE271915 F08002 AW293257 R58383 W95032 AI022248 H18001 R19681 F11341 AA778166 AI435068 AA702525               AW176505 AA318946 AA705230 AW136167 AA704931 AW157512 W93328 AI694445 AW157539 AI301999 AA975516               AA722698 AI569683 AI674496 H17453 AI910812 AI598186 D53709 N80796 AA285026 AA704939 AA159340 AA565703               BE464932 AA477953 AA402072 AA476988 AI929436 AA133096 AI912377 H61238 AI457179 H18002 BE047110 H56139               AA633441 AI500607 AA401959 H55753 AI767655 N93886 AA402908 H78194 D80936 R44236 H61239 BE551612 AI638233               AI953226 AI744095 F09000 Z41080 AI700837 AW768854 AI872712 AA283182 BE383452       320994   9353_4   BE618027 H22381 AA326465 AA326466 AW962215 BE207339       322209   46967_1   H89360 AF086037 H89546       322224   47029_1   AF086064 AA013034 N50099 AW903279       315021   344728_1   AA533447 AF158241 AI240598       322264   47231_1   AF086242 W67679       322265   47233_1   AF086244 W68829 AI539008 W68737 AI685168 AI351133 AI633948       321632   286374_1   AW812795 AA419617 H87827 AW299775 AW382168 AW382133 BE171659 AW392392 BE171641 AA541393       314429   238740_1   BE146577 AA339680 AA972551 BE146576       306624   25108_1   AA329384 S49006 AW405735 AW404287 AW405848 AW405979 BE538908 H70947 AI814190 AA381896 AW582731               AW975580 T94914 AW474500 AW869616 AW974125 AW946246 H44560 AW802184 AI538108 AW609912 AW865715               BE007659 AA443571 AW376161 AW797783 AA713566 AW577973 AA745472 AW270172 AA910107 AA713717 AW364122               AA533898 AI523353 AA715899 H44507 AW947263 AW390753 T89943 R66359 H44320 T64100 AA715879 R54661 AW579645               H68597 AI499528 AI699010 AW605041 AW605043 AA236700 AI290767 H27472 AW079688 T69967 T87728 AW869468               AW873389 AI250670 AA617786 AI566627 AW627605 AW302334 AA617836 AW793186 H16015 R83107 T85409 AA643479               AA582449 AW794654 AI819995 AW865610 AW380149 AW793863 AI281629 T64021 AA501599 R49882 AA565066 R69406               N23918 T59642 R54662 AW973199 R53006 AA401087 AA496563 AW934874 BE171294 AW793133 AI581595 AW605835               AW605040 AW605055 AW605033 AW605058 AA291844 AW382472 AW605005 AA421881 AA513106 AA744190 AW386065               AW613785 AW605829 AA580905 AW605027 AW364134 AA464027 BE012096 BE008565 AA809035 AA809154 AA911395               AA713636 AA745324 AA826230 AW368498 AV646747 T89967 H61164 AI540661 AA721571 C02031 AA523762 AA523746               AI287256 AW841164 AA962139 AW797014 AA515246 AW364140 H45842 T94267 T72111 R49771 T70151 H42664 R83656               R83590 AW380297 AW380263 X95750 T57717 AW391436 AA293355 AW380185 X95749 X95748 X95747 AW796510               AA318628 AI001043 AA744404 AA745567 AA650437 AA715526 AW392762 AA516228               306644   34348_2   BE263222 BE312446 AI002913       306669   7570_1   AI340462 AI583268 AA079086 AI950777 AI301866 AI925108 AW876954 AW877000 AA525418 AA888549 AI934220 AW380220               AA804858 AI927576 T61151 AW384053 BE391691 AA533856 AA248400 T48202 N57156 R68346 R26020 AL050332 W30806               H61369 AA092592 AA230324 BE271217 AW372903 T48772 AA358002 AA094302 AA559856 AW373308 AW373315 AW373297               AW373311 AW373314 AW373309 AW877055 AW770140 AW379805 AI581609 AW364144 AA078921 AA715432 AA654210               AI004899 AA602209 W47464 AA506588 R26822 AU076528 AI535743 AI535704 AI535681       322302   47349_1   W76021 AF088052 W72465       322309   47372_1   W76622 AF086372 W72660       322337   47496_1   AA249804 AF086490 W93549       322340   47509_1   AF088076 W95222 W92523       322362   36526_1   AF039697 AI860821 AW406650 AW515052 R49969 AA834501 AI951401 AA761660       321708   64670_1   AA126365 AA055269 AI768638 N46910 BE047017 AA488423 AW021548 AW612323 AW007669 AI333685 AI633142 AI638022               AI765587 AI151494 AA443764 AI373599 AI140433 AW295946 AA088183 AI811417 AI277748 AL079978 AI341834 AI144434               AA055164 AI765262 AI140147 AI160673 AI686050 AA130038 AI699503 AI580411 AI276910 AW296875 AI927239 AW470427               AI174424 AI675518 N20396 AI308224 BE221055 AI926097 H89681 H90776 AW023381 AA126261 AA025391 AA347308               AA476817 N25488 AA442811 AW297971 AA025454 D81551 D81214 D61126 C15599 AA130037 AA088653 AV654662       321763   166644_1   AA195602 W01148 N40632       313913   653504_2   AW391342 AI813778 AW190911 AI963486 BE049275 AI922735 AI935914 AI263291 AI679178 AW192178 AW338885               AW473496       306710   52443_1   BE564350 AI024221       313960   130872_1   AA113301 AA130859 AI805438 AA846950 AA130915 AW862833       306773   563488_1   AI040750 BE062532       323014   140817_1   AA305198 AW962351 AA134366 AA259244       315276   383168_1   AA860090 AI961138 AW592114 AW087700 AI798907 AW340674       321847   45225_1   T08401 Z83934 T16897               308069   33294_5   AI470895 BE386951 BE391680 BE277351 BE385202 BE300283 BE299619 BE254885 BE391698 T17015 AL048342 BE387417               BE315548 AA345769 AA374932 AA304724 BE277135 T31443 BE387617 AW582877 T33057 AA054826 AA305115 BE378981               BE615689 W07028 BE537075 BE615271 BE252353 BE563255 BE391752 BE545875 AW580149 AA747256 AW276731 N85015               AA299609 AA365061 AA302265 AW951660 BE538115 AW404883 AW583622 AA374519 AA225917 AA037286 W24285               BE255801 BE254061 BE278256 AA377959 AA319628 AA316739 AA378914 W24421 AA658882 N87533 AA526881 AA376559               AA378175 AA300193 AA330503 W69498 C03856 N85298 AW957966 C02647 H19560 BE616753 BE263169 AW250280               AW162197 AW163162 AA301672 AW249055 BE616277 AA225272 AI557298 AW276939 AA327042 N83648 AW404841               AI903202 AA314875 AI546852 BE616559 BE262330 AA385891 BE182717 AI557551 AA082310 AA354394 AI541339 AA327616               AA344981 D53311 AA363102 AA171801 AA089673 AW162085 AA379891 BE277324 AA157651 AA304574 W52799 AA186652    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AA857346 BE294539 BE296371 F31870               BE254168 BE621136 BE295564 BE612812 N88740 AA352787 AW475090 BE270398 BE618807 AI566936 NM_005617               AW008274 BE392312 AI928878 AW162655 AI624147 AA854344 AW952982 AW085710 F01238 AA344919 AA641196               AA720860 AA572870 AW161654 AI001113 AI862725 AI811592 AA320775 AI420790 AI207364 AI951381 BE270095 AI027794               BE513425 BE252494 AA865409 BE294421 AI719767 AA897029 AI564328 AW628239 AI809839 AW082072 BE255143               AI189653 AW515889 AA578771 AW162621 N86168 AA935172 BE384561 AW157031 BE295195 AI659958 AW263875               AA533391 BE513648 AI445700 AI034465 H65716 AW272557 AW302286 BE271816 AW196996 AI953988 AW157372               AA580376 AI191251 AA572856 AI027798 AA884282 BE268198 R92688 AW731956 AI261239 BE260070 BE253635 AA603422               BE258354 AI810163 AA130398 AA861165 BE257787 BE408032 H96956 AA593399 BE275262 AA180066 BE395867 AI439795               AA845816 AW572567 AA999943 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AI718130 W73976 F26566 AI816041 AA633944 AA878094               H61558 AI857355 H45978 F25943 AI879870 F27056 AA244085 AI927367 W69664 W69843 AI298014 N91111 AA229474               AW969539 N95295 AW023874 AW572321 AA481820 AA580774 AI870680 AI568052 AI831105 AI750091 AI141652 AI833250               AW001251 AA180067 AI554189 AI719251 AA807645 AI298013 T52779 AW264018 F21944 AI253714 AA342880 AA985284               T49612 AW263695 AA508894 AA181908 AA533851 N84414 AI277062 T78929 AA534250 AA569444 R11589 AA022468 T60272               AA582353 AA335709 AI929540 AW613761 BE327851 AA533776 W72345 AI601210 AA366049 AA719887 F22515 AI523442               T07133 AA230206 AA827438 AA728986 AI718076 AA504069 AA469341 BE546614 AI434088 AW170241 T52780 AA629409               BE543516 AA484074 W04709 AI582317 BE045496 AA737847 AA535491 AA628352 AA558076 AA864201 AW610533 AI707857               R94198 AA522868 AA226911 AA857018 AA548787 AA627142 H65717 AW166287 AA564007 BE547258 AA330345 C15020    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AA054936 AW151254 F17418 AA908823 AI890234 AA534130               AI468569 AW149483 N22520 AA343231 AW001178 AA602740 AI352348 AA932611 AW273549 AI766324 AW118402               AA888486 AA503847 AW300756 AA585120 AA496674 AA629998 AI619509 AI799389 T25968 AA535332 AA535126 AA467830               AI915716 AA320648 AA585125 AA658579 AW451040 AI735214 F16590 AA284984 AA643858 AA283217 BE178572 AI921154               AA344918 AA557543 AA308479 AA872892 AA481963 AA658578 AW004717 AA290824 H61178 AW474724 AA321490               AA936492       308681   352627_1   AI761307 BE161415 AW005281 AA558937 BE161404       324316   298498_1   AI291330 AA452220 AA443354       324323   273867_1   AA393739 AL138137 AA393796       324368   33663_1   AW861185 AW991306 AI623237 AI018451 AA159072 BE294536 N40680 AA248594 AA332177 AA353889 AW136671               AA063492 AW082601 AI734889 AI479298 AI690289 AA514475 AI827201 AA954932 AI375429 AW305231 AI078116 AI807586               AI224855 AW025809 AA718988 AI093059 AI912915 AA456139 AI341411 N63437 N95744 AI830516 AA846245 N25902               AW469026 AI042513 AI241692 AA988159 AW662812 C03567 AA594584 AW082516 BE068964 AW299374 AI636034               BE172420 AB029022 NM_014914 AW896987 AA765269 BE077785 AA459768 AA436896 AL040331 AA285281 BE244301               T54938 AA093121 F21778 AA150155 AW968251 AA258877 AW663766 AW470130 AI857358 AI469756 AI299480 AI672560               AW089174 AW518770 AA081121 AW014387 AI869379 AA985193 AA152265 W94876       324376   1154206_1   AW499705 AW502537 AW503016       323735   6884_44   BE615406 AA323714 BE515303 AA464826 AA453149 AA442802 BE387695 BE394179 BE392472 BE394406 BE393601               BE394088 BE388690 BE395181       323755   229275_1   AW300094 AA805026 AA700077 AI702882 AA327146       323770   230698_1   AA722425 AA329212 AI572177       302138   228984_1   N83965 AA326737 H14153       325007   428607_1   AA931484 AA758140 AI033284 AA931461 AA757895 AA877176 AA736429 R11591 AI017256       302162   24588_1   AF119046 NM_014481 AJ011311 AB021260 BE091822 BE091819 BE280661 BE548576 BE531337 AW605371 BE547006               BE076387 BE275532 AW386829 AW189348 AA554484 AW028935 AW080283 AW444648 AI538979 AI674393 N59092 C01178               AI612817 AI347385 AI190577 AI918533 BE265083               302183   25243_1   NM_002248 U69883 F11363 M62043 AA350009 AI937237 AI363154 AA351095 AA325431 D60120 D61063 D60321 C15510               AW292489 BE504989 AW594619 AI825516 F09023       324432   312487_1   AA464510 AA631257 AI740516 AI739132 AW972467 AI741376 AW068935 AI467852 AI752240 AI123717 AI754551 AW205510               AW044211 AW028889 AW198033 AI538632 AA513096       323808   247059_1   AW250114 Z43124 AA431421 AI879054 AA351616 AA351035 AL048999       300982   361671_1   AA837754 AA581115       323853   238221_1   AA393460 AA338940 AW966277 AA419006       316664   455916_1   AI042101 AA805541 AA812130 AW977868       323899   48373_1   AL042966 AW403294 BE294048 BE274337 BE261318 BE544865       309470   1028089_−1   AW118833       308859   995_8   AI830787 BE563334       302263   227972_1   AA325517 H19549 R53308       302270   1734192_1   R56151 W91936       302292   27735_1   AF067797 AB013456 NM_001169 AI791955 AW843925 AI732659 AA577625 AW083143 AW138645       301644   867855_1   AW239364 AI792390       301654   103655_1   H81795 Z42291 R20973 AA046920       301660   171572_1   F13112 Z42752 T77015 AA211163       324538   1156268_1   AW502082 AW502979 AW502807 AW501876       301685   326972_1   W67730 Z44630 AA490699 W67596 W76661 R21207       324560   1156518_1   AW502208 AW502366 AW502148       324568   1135567_1   AW502311 AW502370 AW403858       324575   65704_1   AW502257 AI014241 AA100360 BE298534       308994   79433_1   BE261877 AI880051 BE242392       302334   29269_1   AF120491 AF187963 NM_004980 AF205857 AF048713 AL049557       301703   916575_1   AW301478 AW301560 AI889207       301714   1534796_1   F06529 R19994       302399   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AA515246 AW364140 H45842 T94267 T72111 R49771 T70151 H42664 R83656               R83590 AW380297 AW380263 X95750 T57717 AW391436 AA293355 AW380185 X95749 X95748 X95747 AW796510               AA318628 AI001043 AA744404 AA745567 AA650437 AA715526 AW392762 AA516228       303958   10830_7   AL042931 T70163       319668   17848_1   NM_002731 M34181 AA091596 AA090564 AW498491 AA383248 AA018979 AA352938 AL133918 T28731 AA984398 AL134676               AW898293 M77877 AI124701 BE567802 AI288466 AA719614 BE622570       320236   321288_1   AA528811 AA482942       320258   217516_3   BE396475 AW814056 AA311866 H05207 R94015 AA504370 AW962851 T70351       319793   1698018_1   R56360 R20336 R67291 R14290       320360   259694_1   H12405 H12404 AA368159       319886   22717_1   AK000906 AA603325 AI123244 AI742610 AI742621 AW451297 AI963292 N94395 AI122654 AI869312 AA693938 AI913241               R69552 AI925715 AI243319 AI085752 AI094469 AI922008 AI521658 AI288451 AA627433 BE327863 AI417213 AA937953               AW301143 AI827213 AW444808 AI056464 AA736786 AA968590 AI425075 AI420510 AI445367 AI866676 H25733 AI356146               AI803734 AI194056 AI872656 AI222629 Z38818 H25937 AI547263 AI656165 AW590474 T73549 BE392068 H14735 H27088               H45935 AA359427 AW167511       306023   38159_2   BE463655 AA897764       313257   452953_1   N92638 AA781521 AA846225       305406   34836_−76   AA723860       304831   13890_7   AA314337 AI805587 AA402097 AA293631 AA658356 BE566333 AI557276 AV651311 NM_001011 Z25749 AI525506 R97869               BE546683 AA155861 AA532947 AA329269 H63470 AA187471 AV660956 AV650019 AA380909 AW327895 BE313243 N93984               AA354585 W19057 AA428966 T55686 AW958123 AA315872 AA081305 AA083776 AW961442 AA352331 H00860 AA206205               W21515 AA149180 H13044 AA372080 AV658875 AV658874 AA337727 BE276865 AA247683 AA209449 AA393619 AA147378               AW404839 W19374 AW247081 AA311228 BE615971 AA308572 W01826 AA310230 AA412606 AA420575 AA362646 H70797               AA525988 AA311440 BE564044 AW967302 AA302565 AA313021 AA312653 D52864 AA312582 AV654672 AA308096               AA308509 AA308491 AA305867 AA306813 W75940 AV653876 AA365315 AW408185 AA308217 AA122395 AA314083               AA315981 AA311782 AA310647 W46668 N31114 AA180871 AA187276 N72805 AA312418 AA304985 AA167580 AA307881               AA310961 AW674912 AA310126 H82669 AA132497 AA809088 AA155963 AA640361 BE618580 AA229152 AW404970               AA306621 AA308276 N98583 AV660766 AA654587 AA206190 AA312305 AA580740 AI568153 AI718253 AI860477 AI872388               AA873460 AA405147 AA315435 AI129479 AI888709 AW583033 AW089596 AW264185 AI653503 AA858344 BE619226               AA187721 AA306691 AW439857 BE616042 AI889905 AI862869 AA309960 AA307823 AI148769 BE619772 AA582168 AI963414               AW168760 AW167856 BE619400 BE378974 BE619933 AW958117 W49703 AI951380 AA306263 AA583192 AA356605               AA897095 AA149141 T53975 AI744255 AA845352 BE312890 AW961435 AW583101 W24684 BE619333 T96513 AI491903               BE272296 AA315556 BE539380 BE619999 AW084687 BE465646 BE262138 AA999923 BE260616 BE276306 D55310 AI186578               AI707735 AW404371 BE274614 AW512395 AA650425 AI439470 AA513739 AW404673 AW404664 M77233 AI970731 AI880754               AI418821 AW273410 AA069936 AW058084 AA719351 AW404422 AW405314 AI523106 AA393107 BE408961 BE252375               AA578681 BE513748 AI749494 N36979 N43025 D11774 AW391958 R34130 BE394953 AI865715 AI018059 N46292 AA908866               AA907443 AW081633 AA622318 AW438511 BE262297 AA565643 AI018057 AI440067 AI719291 AA135054 BE222834               AW262240 AA081120 AA442581 N86460 AA583569 AI061357 W72482 AA148278 AI186761 AA512934 AW615804 AA595332               AI831069 AA778136 AA657641 AI433175 AA398698 AI735084 BE183158 AI566940 AW304785 AI401846 AA506149 AA102508               AA736531 AI027939 AW000716 AA861339 AI027937 AA575877 AA639090 AW129111 AI421179 AA506553 AA936780               AA972869 AA563975 AA582448 AI802748 AI471162 AA586422 N86248 AA528142 AA551225 AI566307 AI206730 AA513485               AA363629 AA436824 AW575828 AA180774 AI001103 AA932070 AA613667 AI337566 AA582127 AW327319 AA610833               AI333738 AI708124 AI349480 AI240444 AI225152 AA570790 AI539813 W80674 AI333517 AA181299 AA315527 AI719857               BE087137 AW474616 AI510739 AA614724 AW337476 AW951820 AA149181 AA149142 AA523097 AA428873 AI708760               AI978984 AA946913 AA844685 AI440225 AA306527 BE349026 AI659593 AA845752 AW327366 AA311945 AA595594 AI027199               AI499554 AI262336 AA398535 AI333388 AW575598 AI472745 AI476623 AI150520 AW897766 AI864033 AW584030 AA148411               BE348977 AA420550 AW768575 T27844 AI349314 AI371037 AI675707 AW102842 AI203978 AI719821 AW768495 AW021575               AI686981 R36541 AI346551 AW888705 R25390 AA209335 AI342426 AA056446 AA582981 AA890201 AW026850 AA857587               N91141 AW768541 T55235 AA401942 AA080860 AI291273 AI312669 AA412271 AA890649 AA846264 BE019907 BE090895               T56904 H70798 AI500573 AW327642 F17734 AA157192 AA152417 AW327670 AA985481 H71524 AW439687 AA968516               AW327857 AA405330 AI342315 H01239 AA878156 AA148279 H71525 N52399 AI991878 AA878100 N93956 H56020 AA132515               W49704 H63414 AI717990 AI814318 AA912383 AA922317 R97819 AI860255 AI335093 AI187843 AW270357 AA187646               AI190237 AI991126 W07024 BE539453 AI819841 H75424 AA102446 AW026974 AI923973 AW001389 AA337759 N70772               AW022155 AA336624 AI219252 N89590 AA664546 AW339690 AA651993 AA608735 H65064 AA857788 T81916 AA860215               AI031685 AA133689 AA186954 R16825 N27213 AA857155 N69981 AA318664 AI735334 H82411 AI460293 AA205819               AW803036 AI922965 N33363 AA580622 AA664756 AA651961 AI201624 AI066494 AA834187 AA187722 AA652066 W80675               AW051553 AW263699 R34131 AA340971 AA364263 AI824574 AI356913 AI439263 AA205822 AI540881 AA640625 AI206794               AI198883 AA167581 AA970474 AA299068 AA157088 N90120 AI371330 AA090914 AI889887 AI274617 AA730747 AI745000               AW265227 AI358313 AA122396 AA501489 AA918963 AA953637 AI434343 AI707767 AA603889 W04799 T55604 AA614231               AA071264 AA083777 AI880809 AI185259 AA747112 AA908459 AA134970 AI192649 BE046107 AI358698 AA310968 AW517574               AA984892 W46578 AW105597 AA224970 AA747937 T96514 AI472689 AA283670 AI186789 F35482 AW873463 AW361039               AA583072 AI872660 AA040277 AA224895 N85343 AA484723 AA937597 AI304419 AA228409 AA501488 AA664896 AA664966               AA482963 AA736806 AA528814 AA927560 AA328094 N83225 AA582536 AA938377 AA916871 AA507716 AA101182 AI720885               AA876858 AA483322 AA362647 N75592 N23917 AI193949 N74054 AI352629 D51754 AI570783 AA470923 AW975162               AA328256 AA659768 AI919411 W40458 F00799 AA147346 AA728856 AA528675 AI676101 AA523785 T52866 AA533842               AW516442 AA554875 AA886066 AW518472 AA971169 AA908345 AI561318 AA482746 AA482735 AA482882 AA188350               AA629989 AA482917 AW263351 T52867 D52318 AI696386 AA689276 AI719128 AI719124 AA541702 X85626 AA640165               AA228408 AI832575 AI143550 AI281727 N73099 AA733095 AI749387 X85625 AA640766 AA652170 AA652139 AW606146               AA649563 T25406 AA327330 AA080984 X74803 AA746016 AW957997 AI005578 BE547070 AA886825 AA927742 AI927866               AA528573 AA665260 AW270340 AI698507 AA501524 AA483113 AA506345 N91789 AI933429 AW904843 BE092709 BE093487               BE093472 BE092712 F22641 N80062 AW455220 BE079292       319900   1138215_1   AW408392 AW847299 AW847302 T86065 T85884 T77135       321121   1545647_1   W23285 H42714 F25381 F37215       321132   117535_1   AA081495 R87345 H43858 BE266428 BE263090       320503   25164_1   NM_005897 AF156857 AA346876 BE545147 AI003306 N45644 AW889728 BE007236       320586   26170_1   NM_003658 AF031924 AJ243512 AI792204 AI675861 AI915798 AI733496 AI823489 AI370544 AI696665 AA991537       305557   41560_1   AA774834 AK001079 BE293936 AW372365 BE271898 F00113 AA424108 AI950409 W70049 N56481 BE046416 W70050               AI619669 AL040446 AA996189 AA962427 W37166 AA179135 Z21574 N64837 BE562818       304978   28800_7   BE259406 BE379716 AA147786 BE300171 BE267161 BE515287 AU076914 AW374229 AA069647 BE561555 D53431 D54395               AA191250 D52650 BE208576 BE566731 BE387383 AA373416 R23516 T68691 T69334 AA355791 R02636 BE566591               BE407444 AI982546 H49682 AA094446 BE515225 D54740 AA095798 AA196716 AA353034 AW955137 D53869 AA100150               AA188091 AI524940 D54982 AA090373 D53479 AA247363 BE567604 BE391813 N41527 BE410575 AA380139 BE616028               AW881909 AW963736 BE276064 BE380156 BE566181 BE567132 BE561903 AI205098 X52851 AW881897 BE616573               BE298397 AA127519 R88890 BE616648 BE279162 BE559666 BE514563 BE312454 BE407312 BE276098 BE394047               BE267326 BE276908 BE565569 BE385054 BE265740 BE409229 H44489 AA207193 AI525570 BE304612 BE396965 BE386123               BE264758 BE266121 AA215851 BE295137 BE512683 BE388849 AA223494 BE263350 BE408879 BE386132 BE382906               BE271789 BE539264 BE378507 BE567995 BE208471 Y00052 BE256484 BE260931 AL021395 BE260620 BE512892 AI906447               BE615419 BE560786 BE279517 H46528 BE258084 BE535992 BE274774 BE274916 BE260585 BE563269 BE249941               BE264782 BE408521 BE312750 BE559964 AA147099 T70141 AV661600 AA581711 AA186462 T69259 AA521058 AA563932               BE397758 T68848 BE514531 H50191 AA641322 AI869370 AA653502 T70072 AW139957 AA069924 AI953984 C06029               AA190399 AA617735 AA085181 AA506423 AI470746 C05982 BE077432 AW945661 BE272794 AA011065 AA922406 BE183113               AA564289 AA374410 AI264729 AW957628 T68610 AA143328 AW381780 AW381880 AA135191 AA857453 AA112231               AA011066 F36776 AW798236 H00395 BE272608 AW798123 AA532416 AI936732 BE183271 AA129828 AA741102 BE164382               AW799104 AW997926 AA211136 AW601437 AW602618 H11277 AA083462 AA056516 AW364819 R01694 AA086193               BE171120 BE093136 AW796864 AA663009 AW605266 AA247458 AW796905 BE171125 AW392363 BE171106 BE171110               AW796810 AW796854 AW578648 AI221714 AW151499 AW937186 BE293542 BE249842 AW363879 AI701218 AW084288               AA489447 AW798124 AW798256 AA658272 U46266       304983   25108_1   AA329384 S49006 AW405735 AW404287 AW405848 AW405979 BE538908 H70947 AI814190 AA381896 AW582731               AW975580 T94914 AW474500 AW869616 AW974125 AW946246 H44560 AW802184 AI538108 AW609912 AW865715               BE007659 AA443571 AW376161 AW797783 AA713566 AW577973 AA745472 AW270172 AA910107 AA713717 AW364122               AA533898 AI523353 AA715899 H44507 AW947263 AW390753 T89943 R66359 H44320 T64100 AA715879 R54661 AW579645               H68597 AI499528 AI699010 AW605041 AW605043 AA236700 AI290767 H27472 AW079688 T69967 T87728 AW869468               AW873389 AI250670 AA617786 AI566627 AW627605 AW302334 AA617836 AW793186 H16015 R83107 T85409 AA643479               AA582449 AW794654 AI819995 AW865810 AW380149 AW793863 AI281629 T64021 AA501599 R49882 AA565066 R69406               N23918 T59642 R54662 AW973199 R53006 AA401087 AA496563 AW934874 BE171294 AW793133 AI581595 AW605835               AW605040 AW605055 AW605033 AW605058 AA291844 AW382472 AW605005 AA421881 AA513106 AA744190 AW386065               AW613785 AW605829 AA580905 AW605027 AW364134 AA464027 BE012096 BE008565 AA809035 AA809154 AA911395               AA713636 AA745324 AA826230 AW368498 AV646747 T89967 H61164 AI540661 AA721571 C02031 AA523762 AA523746               AI287256 AW841164 AA962139 AW797014 AA515246 AW364140 H45842 T94267 T72111 R49771 T70151 H42664 R83656               R83590 AW380297 AW380263 X95750 T57717 AW391436 AA293355 AW380185 X95749 X95748 X95747 AW796510               AA318628 AI001043 AA744404 AA745567 AA650437 AA715526 AW392762 AA516228       321223   249691_1   AA431366 AA490423 H96381 AA361614 H56121 AA354669       321240   2628_30   X58799 AF071472       321286   236538_2   BE245833 BE539992 AI380940 AW952644 AA535470 R84610       313476   83849_1   AA010267 AA720674 AA010209       312854   467476_1   AA837782 AA828713 H84206 AW979069       321304   115882_1   BE260893 AA078319 R85057 AW803024 H85811 AA078293       321321   32811_1   AB033072 AW163387 AW161566 T08007 AW161909 AW157331       321325   28266_1   AB033100 AA347036 BE260325 AW961669 AL047207 AA347037 AI766894 AA601045 AI559897 AW139033 AW274622               AW172884 AW089070 AA804340 AW798925       321354   116028_−2   AA078493       321359   41877_1   AW972301 AW474412 AJ227863 AA516297 AA641949 AW995029       320727   36759_63   AW003360 AI971548 AA017585 X80306 X91133 AJ276100 X91132 AF064499 AF064495 AF063768 X83713 AW951310               AW975565 AA721610 AA715972       320767   18895_2   H54398 AA700844 AW895023 BE549308 AW834812 AA299525 AW957027 AA001789 BE219218 R73244       322012   22619_2   AL137357 AW173064 AW662837 AI222955 AI138884 AW438842 AA883686 AA978208 AA653137 AA906477 AI150554               BE295082 BE243550       306406   AA971973       306426   AA975039       306443   AA976950       306511   AA988891       320965   266751_1   H18166 R86173 H19851       306531   AA991423       306546   AA993109       306549   AA993796       306558   AA994743       306590   AI000246       306591   AI000248       329464   c_y_hs       336695   CH22_4181FG_48_4 —         329496   c10_p2       336705   CH22_4209FG_63_2 —         336717   CH22_4234FG_81_1 —         306668   AI004890       306739   AI028393       306791   AI042387       329665   c14_p2       336883   CH22_4625FG_322_2 —         336898   CH22_4647FG_330_1       308016   AI445116       308082   AI473682       338177   CH22_6725FG_LINK_EM: AC00       308092   AI474896       308097   AI475411       306801   AI052653       306809   AI057134       336908   CH22_4670FG_343_2 —         336917   CH22_4688FG_346_4 —         306839   AI077385       306866   AI086683       306881   AI088695       308115   AI479071       308127   AI492187       308138   AI494446       306919   AI096832       306930   AI124518       329824   c14_p2       329839   c14_p2       306975   AI127042       308258   AI565612       308282   AI569456       308311   AI581855       308382   AI624301       308385   AI625428       308406   AI634885       308449   AI660854       308465   AI672480       308517   AI689279       308539   AI694191       308544   AI695133       308548   AI695484       338648   CH22_7413FG_LINK_EM: AC00       308572   AI707882       338668   CH22_7441FG_LINK_EM: AC00       308582   AI709056       338679   CH22_7453FG_LINK_EM: AC00       308598   AI719237       338686   CH22_7461FG_LINK_EM: AC00       308601   AI719930       338703   CH22_7483FG_LINK_EM: AC00       338705   CH22_7485FG_LINK_EM: AC00       338725   CH22_7521FG_LINK_EM: AC00       338747   CH22_7561FG_LINK_EM: AC00       308676   AI761036       338770   CH22_7593FG_LINK_EM: AC00       308695   AI763350       308707   AI769997       308718   AI798009       308851   AI829820       308954   AI868958       308961   AI870246       333043   CH22_269FG_70_4_LINK_EM: A       333054   CH22_280FG_73_8_LINK_EM: A       308991   AI879831       303582   647662_1   AA377444 AI458965       305018   AA627127       305030   AA629988       305046   AA632201       335131   CH22_2463FG_497_15_LINK_E       335157   CH22_2493FG_501_7_LINK_EM       305071   AA640579       335163   CH22_2499FG_502_7_LINK_EM       305080   AA641485       335174   CH22_2510FG_504_4_LINK_EM       305093   AA642917       305116   AA649244       335200   CH22_2538FG_508_9_LINK_EM       335201   CH22_2539FG_508_10_LINK_E       335217   CH22_2556FG_512_3_LINK_EM       305134   AA653159       305145   AA653589       328015   c_6_hs       328016   c_6_hs       335234   CH22_2573FG_515_3_LINK_EM       335236   CH22_2577FG_515_8_LINK_EM       328025   c_6_hs       335247   CH22_2589FG_516_8_LINK_EM       305167   AA663080       305168   AA663105       328031   c_6_hs       335262   CH22_2604FG_520_3_LINK_EM       335265   CH22_2607FG_521_1_LINK_EM       335266   CH22_2608FG_521_2_LINK_EM       328053   c_6_hs       305197   AA666301       335281   CH22_2623FG_524_4_LINK_EM       335284   CH22_2626FG_526_6_LINK_EM       328098   c_6_hs       303929   AW470753       303933   AW471472       326806   c20_hs       326808   c20_hs       326857   c20_hs       326874   c20_hs       326876   c20_hs       326884   c20_hs       335311   CH22_2654FG_532_4_LINK_EM       305234   AA670431       335320   CH22_2664FG_534_7_LINK_EM       328109   c_6_hs       335331   CH22_2675FG_535_4_LINK_EM       335339   CH22_2686FG_535_16_LINK_E       305259   AA679225       335340   CH22_2687FG_535_17_LINK_E       335344   CH22_2691FG_536_3_LINK_EM       335348   CH22_2695FG_537_4_LINK_EM       335349   CH22_2696FG_539_2_LINK_EM       305264   AA679505       328134   c_6_hs       335371   CH22_2720FG_543_9_LINK_EM       335377   CH22_2726FG_543_17_LINK_E       328171   C_6_hs       326942   c21_hs       326943   c21_hs       326957   c21_hs       326981   c21_hs       326997   c21_hs       305335   AA704235       335421   CH22_2772FG_551_1_LINK_EM       328221   c_6_hs       328224   c_6_hs       328228   c_6_hs       335448   CH22_2799FG_562_5_LINK_EM       305361   AA708902       335451   CH22_2802FG_562_9_LINK_EM       328236   c_6_hs       335455   CH22_2806FG_562_15_LINK_E       328243   c_6_hs       335468   CH22_2819FG_567_4_LINK_EM       335470   CH22_2821FG_568_3_LINK_EM       335482   CH22_2834FG_570_11_LINK_E       335485   CH22_2837FG_570_17_LINK_E       328271   c_6_hs       328276   c_7_hs       328277   c_7_hs       328282   c_7_hs       305403   AA723748       335517   CH22_2872FG_571_34_LINK_E       328305   c_7_hs       335523   CH22_2878FG_572_3_LINK_EM       335527   CH22_2882FG_572_7_LINK_EM       305443   AA736653       328314   c_7_hs       335536   CH22_2891FG_574_2_LINK_EM       305454   AA738413       328328   c_7_hs       305464   AA742425       335565   CH22_2921FG_579_1_LINK_EM       335566   CH22_2922FG_580_1_LINK_EM       305486   AA748889       335585   CH22_2943FG_581_24_LINK_E       335587   CH22_2945FG_581_26_LINK_E       335593   CH22_2951FG_581_32_LINK_E       335606   CH22_2964FG_582_3_LINK_EM       305536   AA770682       305547   AA773111       335634   CH22_2994FG_584_14_LINK_E       328420   c_7_hs       328428   c_7_hs       335651   CH22_3011FG_590_2_LINK_EM       335652   CH22_3012FG_590_3_LINK_EM       328436   c_7_hs       328444   c_7_hs       335667   CH22_3027FG_590_18_LINK_E       328462   c_7_hs       328467   c_7_hs       335687   CH22_3048FG_596_2_LINK_EM       335690   CH22_3051FG_596_5_LINK_EM       328474   c_7_hs       335692   CH22_3053FG_596_7_LINK_EM       335693   CH22_3054FG_596_8_LINK_EM       328484   c_7_hs       335700   CH22_3061FG_598_1_LINK_EM       305621   AA789095       305632   AA805276       335720   CH22_3081FG_599_23_LINK_E       335721   CH22_3082FG_599_24_LINK_E       328504   c_7_hs       328506   c_7_hs       328507   c_7_hs       335733   CH22_3095FG_601_3_LINK_EM       335739   CH22_3102FG_601_10_LINK_E       335745   CH22_3108FG_601_16_LINK_E       335747   CH22_3111FG_601_20_LINK_E       335750   CH22_3115FG_602_4_LINK_EM       335755   CH22_3122FG_604_4_LINK_EM       328544   c_7_hs       335768   CH22_3137FG_607_2_LINK_EM       305686   AA812726       328552   c_7_hs       335774   CH22_3143FG_607_10_LINK_E       328557   c_7_hs       328558   c_7_hs       335777   CH22_3146FG_607_13_LINK_E       305697   AA814956       335782   CH22_3151FG_609_4_LINK_EM       335783   CH22_3152FG_610_3_LINK_EM       328589   c_7_hs       335787   CH22_3156FG_611_3_LINK_EM       328570   c_7_hs       328581   c_7_hs       328582   c_7_hs       328592   c_7_hs       337011   CH22_4876FG_427_6 —         337023   CH22_4894FG_433_12 —         337032   CH22_4910FG_438_3 —         337069   CH22_4967FG_448_2 —         337092   CH22_5016FG_465_12 —         337093   CH22_5017FG_465_18 —         337094   CH22_5018FG_465_19 —         337097   CH22_5028FG_471_1 —         305700   AA815428       335806   CH22_3178FG_616_8_LINK_EM       335817   CH22_3189FG_618_5_LINK_EM       328607   c_7_hs       335827   CH22_3200FG_620_1_LINK_EM       335831   CH22_3204FG_620_5_LINK_EM       335832   CH22_3205FG_620_6_LINK_EM       328620   c_7_hs       328624   c_7_hs       328636   c_7_hs       335863   CH22_3238FG_629_8_LINK_EM       305782   AA844730       305787   AA845035       328662   c_7_hs       335895   CH22_3272FG_635_3_LINK_EM       337100   CH22_5031FG_472_3 —         337114   CH22_5060FG_494_17 —         337121   CH22_5096FG_519_1 —         337132   CH22_5112FG_526_3 —         337168   CH22_5188FG_562_28 —         307085   AI160868       337170   CH22_5190FG_564_1 —         337172   CH22_5192FG_565_2 —         307090   AI161024       305803   AA846052       305808   AA853958       305816   AA854776       335902   CH22_3279FG_635_10_LINK_E       335920   CH22_3297FG_636_16_LINK_E       305841   AA860348       305867   AA864572       335956   CH22_3334FG_647_3_LINK_DJ       305877   AA865649       335968   CH22_3347FG_652_1_LINK_DJ       335971   CH22_3350FG_652_4_LINK_DJ       335975   CH22_3354FG_652_9_LINK_DJ       335980   CH22_3360FG_653_2_LINK_DJ       328768   c_7_hs       328770   c_7_hs       335993   CH22_3373FG_656_6_LINK_DJ       335998   CH22_3379FG_656_16_LINK_D       335999   CH22_3380FG_657_1_LINK_DJ       328791   c_7_hs       337203   CH22_5256FG_591_3 —         337204   CH22_5261FG_595_1 —         307120   AI184343       307140   AI185762       307177   AI188864       305903   AA873085       305925   AA877883       328803   c_7_hs       330002   c16_p2       328810   c_7_hs       328820   c_7_hs       330021   c16_p2       305967   AA886428       328835   c_7_hs       305971   AA886874       328841   c_7_hs       305984   AA887654       328851   c_7_hs       328859   c_7_hs       330057   c17_p2       330058   c17_p2       305999   AA889603       307215   AI193189       307262   AI202100       307318   AI208577       307380   AI222985       307433   AI244895       307437   AI245683       307556   AI281651       307558   AI281998       337645   CH22_5960FG_LINK_EM: AC00       337657   CH22_5976FG_LINK_EM: AC00       307574   AI283549       307588   AI285535       307592   AI285739       337685   CH22_6020FG_LINK_EM: AC00       337695   CH22_6033FG_LINK_EM: AC00       337697   CH22_6037FG_LINK_EM: AC00       307606   AI290006       307629   AI300246       307642   AI302103       307643   AI302124       307646   AI302236       307703   AI318588       307728   AI335557       307752   AI339447       307799   AI351112       309005   AI884454       307864   AI367417       307877   AI368880       307899   AI380270       309108   AI925949       309169   AI949216       309181   AI951727       307904   AI381019       307912   AI382224       307918   AI383496       307954   AI419692       307961   AI421059       307992   AI434166       309206   AI961962       309233   AI971416       309245   AI972447       309247   AI972768       309275   AI989570       309324   AW015373       309333   AW025709       309343   AW028652       309351   AW057547       309403   AW082954       309533   AW151131       309592   AW172384       325271   c11_hs       325285   c11_hs       325289   c11_hs       309600   AW182066       309605   AW182800       309759   AW268822       309767   AW271805       309815   AW292760       309859   AW298760       302681   31257_1   X97550 X97552       302683   31326_1   X85153 T63701       309958   AW444488       309977   AW451663       309985   AW452919       302727   32493_1   L10141 L10151 L10148 L09095       302747   32813_1   AF062275 L03830       304022   T02990       304055   R07994       304056   R08577       304060   T61464       304125   H40976       304127   H42981       304134   H54627       304195   N35382       302952   39444_1   AF103179 U82961       302996   41196_1   AF054663 AF124197 R70292       304269   AA069029       304324   AA137045       304330   AA157834       304424   AA293494       304465   AA421948       304467   AA424703       304480   AA430373       304485   AA434076       304487   AA434241       304559   AA488050       304575   AA496437       304605   AA513225       304612   AA514207       304623   AA521331       304635   AA523976       304667   AA535602       304674   AA541735       304675   AA541740       304693   AA554263       304696   AA554758       304707   AA564846       304731   AA576085       304734   AA576428       304745   AA577771       304746   AA577793       306009   AA894560       306012   AA896989       306053   AA905312       306081   AA908472       306090   AA908609       304811   AA584361       304813   AA584540       304817   AA584712       304833   AA586504       304841   AA587541       304887   AA599355       306137   AA916176       306180   AA922503       306183   AA922622       306193   AA923457       304918   AA602697       304968   AA614308       306200   AA926816       306220   AA928363       306221   AA928686       306300   AA937573       320789   252516_1   R78712 AA603646 R78713       306351   AA961356       330435   41165_1   U63836 AW842139 X74956 U78550 AW840802 X74954 AW388241 AW842709 AF253321 X74955 X74370 AW363799               BE073386 AI791962 AA587390 AW840865       330436   10605_34   BE259039 W29128 AW410299 X72990 BE246492 NM_005243 X66899 AI909006 AW248151 AL031186 AA012966 BE273549               BE311429 BE253102 Y07848 BE538102 BE256863 BE261240 BE312156 BE618412 BE257322 BE620446 AW806629               AA376777 AA325384 BE256808 BE251039 BE257878 BE275352 AA357169 AW403562 AA204995 AA093259 W95953               BE256279 BE336683 BE252465 BE251266 AA380754 BE294942 AA380941 AA380999 BE297164 BE249995 BE294719               BE295372 AI270673 BE305132 BE563752 BE295357 AI525421 BE263980 AA057505 AA020915 BE266318 BE206948               AI474020 BE296420 BE297374 BE408545 BE019366 BE407372 BE266180 BE279437 R58233 T19567 BE300738 AW381179               AA357571 AW361285 AA436908 AA301019 AA301022 N20202 BE408777 BE548638 BE167415 AA071260 BE088429               BE280092 W23117 T19568 R51681 AW402216 W22784 BE185607 AI457224 BE544120 AL134874 S72620 AA375079 D51319               AW818280 BE514686 AW853024 BE563744 AA300469 T07592 BE622190 BE272834 W21781 BE315450 BE542367 BE393120               AA988441 H55137 BE562296 BE622502 BE395960 AA329733 AA332348 AI768317 AA456866 AI497832 AW878437 AA857042               U18018 BE621418 AI818790 AI949507 BE397693 AI885545 AI858854 AI355147 BE169028 S62138 AW732191 AA856891               BE266060 X71427 BE268557 AF095890 AW001288 AI799634 AI623498 AA071346 BE547662 BE261446 AI564543 BE559759               U35622 BE314249 BE264915 AI638591 AI538385 AW090025 BE384754 AI888689 AW778800 AI925273 AA075797 AW949130               AV660275 AW438697 AI587137 AI524121 AA806249 AW628247 AA808241 AI244388 AI761125 AW117672 AA911782               AI129250 AA654447 H55291 BE258050 BE206162 W95867 AA857187 AI871378 AI660103 AW103827 AI220929 AW149949               BE465561 AI302857 AW168841 D82190 AW249814 AI623432 AI687358 AW951077 R51592 W60458 AI092863 AW474693               D12765 AI911646 D82208 D82187 AW074031 AI358527 AW338497 AA970893 AW072573 AA205364 AI858886 AA012830               AW148763 AI863056 AA548656 BE250325 AI016994 AI864005 BE046122 AI497746 C75340 R58896 D82141 AW168240               C19048 AI741090 D29465 AI222365 AA948288 AI583522 AW572212 AI091290 AA582727 AA579897 AA570629 W60883               AW516989 AL038160 AA577334 AI865872 AA994043 AA922583 AA464778 AA209178 AI829479 AI370235 BE246529               AA384177 AA456255 AI699730 W60654 AL035744 AA862042 R32756 AI886886 AA993087 AI289479 AA627840 AA464184               AI619503 R32755 AW075358 AI432315 AA457024 AA020865 R92132 AA454629 AA746059 AA454643 AA456240 AA826984               BE163738 AI806470 AI991074 AI802560 AA587095 AA558714 AA968521 N87780 AI538246 N71794 AV661738 AI368903               AA362570 AI989445 AI674962 S75762 BE245204 AA975296 D20123 AW005704 AA693328 AA582270 AI918474 AW205707               AI696299 AA220990 AA101538 T29030 H27201 AW262526 AI610530 AA126840 AA126790 X92120 AW367868 BE299644               BE299451 AA476561 BE300044 AA134363 BE295222 AA307504 N42337 AA319098 N39502 AW964461 N57241 BE299049               N86332 R51156 AA085859 T75212 AA133939 AA147129 AA156161 BE543953 BE538848 AA133676 BE299745 AA135050               AA218535 AW406401 AW411287 BE410528 C01410 NM_004083 BE314959 AA836413 AA085862 AW024370 AA471059               AW467508 AA001025 AI828231 AA633221 T95517 AA147038 AA476447 AW027012 AW078627 BE513200 AI192297               AA886279 AW081806 AA316185 AA010506 AI269929 W93139 AI682935 AA609555 AA378028 AI093877 AA999997 AA730698               AI143923 AW575315 AA890550 AA494353 AW576601 AI796336 AA826130 AA609207 AI539618 AI088539 AI089090 AA825505               AA632978 AA015892 AW204713 AA156495 AA824613 AA133630 N29826 AA527476 AI633352 T27908 AA134364 AA133940               AW043601 H37775 AA772375 AA057871 AA047888 AA054225 H86568 AA001511 H25718 AW189507 AA165589 AA054433               H85549 AA165486 AA058972 AA454911 AA464064 AA493802 AA428253 R85508 AW302469 AI611812 BE162582 F11073               T95518 N26811 AI783929 H40669 AW611745 AI658803 R51042 R45276 AA528386 AA782875 AW880218 AL138391 AA314536               AW949338 AA149466 AA149552 AI346513 AA216776 BE349131 AW007654 AI141803 AA622688 AI185131 AW057635               AA101539 AA627986 H27202 AI536847 W93084 AI973148 AI246788 AW572108 AI469414 AA454835 AA612707 AA430746               AI084991 AA010400 AA856636 AA463928 AI248310 R07170 AA834033 D12244 AI655670 AA054350 AA639480 AI702067               AI475389       330527   14558_−15   S77356       330833   103550_1   AA046804 AA046821       330855   111881_1   AA070316 AA079318       332099   genbanK_AA608983   AA608983       332240   genbank_N54803   N54803                       # using Clustering and Alignment Tools (DoubleTwist, Oakland California). The Genbank accession numbers for sequences comprising each cluster are listed in the “Accession”column.                                     
     [0348]                           TABLE 1-20B                       Pkey   Ref   Strand   Nt_position                  332792   Dunham, I. et.al.   Plus   73381-73768       332843   Dunham, I. et.al.   Plus   1142859-1143494       332909   Dunham, I. et.al.   Plus   1946582-1946735       332920   Dunham, I. et.al.   Plus   2007562-2007785       332947   Dunham, I. et.al.   Plus   2431726-2432006       332949   Dunham, I. et.al.   Plus   2436245-2436348       332958   Dunham, I. et.al.   Plus   2516164-2516310       332992   Dunham, I. et.al.   Plus   2699997-2701093       332993   Dunham, I. et.al.   Plus   2701550-2701685       333004   Dunham, I. et.al.   Plus   2759056-2759165       333006   Dunham, I. et.al.   Plus   2762853-2762953       333007   Dunham, I. et.al.   Plus   2763569-2763709       333132   Dunham, I. et.al.   Plus   3358040-3358153       333133   Dunham, I. et.al.   Plus   3360058-3360195       333139   Dunham, I. et.al.   Plus   3369495-3369571       333152   Dunham, I. et.al.   Plus   3612171-3612354       333205   Dunham, I. et.al.   Plus   3942727-3943009       333221   Dunham, I. et.al.   Plus   3978070-3978187       333225   Dunham, I. et.al.   Plus   3992229-3992386       333245   Dunham, I. et.al.   Plus   4157587-4157668       333248   Dunham, I. et.al.   Plus   4162041-4162139       333261   Dunham, I. et.al.   Plus   4336597-4337752       333272   Dunham, I. et.al.   Plus   4381561-4382212       333281   Dunham, I. et.al.   Plus   4506230-4506342       333283   Dunham, I. et.al.   Plus   4514226-4514360       333288   Dunham, I. et.al.   Plus   4516841-4516939       333298   Dunham, I. et.al.   Plus   4581537-4581947       333306   Dunham, I. et.al.   Plus   5396233-5396310       333382   Dunham, I. et.al.   Plus   4905796-4905913       333403   Dunham, I. et.al.   Plus   4925140-4925256       333420   Dunham, I. et.al.   Plus   4954302-4954465       333428   Dunham, I. et.al.   Plus   4973869-4974007       333464   Dunham, I. et.al.   Plus   5210762-5211300       333465   Dunham, I. et.al.   Plus   5211385-5211858       333488   Dunham, I. et.al.   Plus   5396233-5396310       333515   Dunham, I. et.al.   Plus   5564299-5564851       333520   Dunham, I. et.al.   Plus   5686133-5586296       333566   Dunham, I. et.al.   Plus   5954226-5954473       333567   Dunham, I. et.al.   Plus   5959139-5959515       333571   Dunham, I. et.al.   Plus   6007916-6008058       333572   Dunham, I. et.al.   Plus   6026896-6027189       333576   Dunham, I. et.al.   Plus   6090345-6090721       333577   Dunham, I. et.al.   Plus   6123950-6124281       333580   Dunham, I. et.al.   Plus   6142935-6143145       333587   Dunham, I. et.al.   Plus   6250599-6250966       333588   Dunham, I. et.al.   Plus   6255445-6255779       333591   Dunham, I. et.al.   Plus   6285884-6286251       333592   Dunham, I. et.al.   Plus   6297731-6297976       333593   Dunham, I. et.al.   Plus   6304132-6304428       333594   Dunham, I. et.al.   Plus   6308990-6309450       333599   Dunham, I. et.al.   Plus   6337885-6338255       333600   Dunham, I. et.al.   Plus   6355629-6355925       333601   Dunham, I. et.al.   Plus   6360075-6360442       333607   Dunham, I. et.al.   Plus   6504431-6504690       333608   Dunham, I. et.al.   Plus   6510834-6511130       333619   Dunham, I. et.al.   Plus   6562799-6562926       333623   Dunham, I. et.al.   Plus   6584559-6584956       333625   Dunham, I. et.al.   Plus   6603020-6603310       333626   Dunham, I. et.al.   Plus   6614174-6614467       333627   Dunham, I. et.al.   Plus   6620584-6620903       333628   Dunham, I. et.al.   Plus   6629004-6629233       333629   Dunham, I. et.al.   Plus   6636915-6637205       333631   Dunham, I. et.al.   Plus   6650904-6651011       333632   Dunham, I. et.al.   Plus   6651520-6651658       333635   Dunham, I. et.al.   Plus   6663683-6663973       333637   Dunham, I. et.al.   Plus   6674968-6675134       333640   Dunham, I. et.al.   Plus   6688350-6688624       333642   Dunham, I. et.al.   Plus   6708760-6709139       333643   Dunham, I. et.al.   Plus   6728053-6728343       333646   Dunham, I. et.al.   Plus   6739110-6739379       333647   Dunham, I. et.al.   Plus   6772502-6772779       333648   Dunham, I. et.al.   Plus   6787465-6787782       333650   Dunham, I. et.al.   Plus   6796852-6797128       333652   Dunham, I. et.al.   Plus   6809455-6809573       333653   Dunham, I. et.al.   Plus   6811130-6811392       333654   Dunham, I. et.al.   Plus   6816731-6816993       333656   Dunham, I. et.al.   Plus   6822087-6822406       333657   Dunham, I. et.al.   Plus   6831369-6831445       333658   Dunham, I. et.al.   Plus   6835282-6835474       333668   Dunham, I. et.al.   Plus   7011009-7011223       333670   Dunham, I. et.al.   Plus   7027945-7028181       333680   Dunham, I. et.al.   Plus   7071730-7071794       333682   Dunham, I. et.al.   Plus   7076641-7076760       333698   Dunham, I. et.al.   Plus   7205279-7205383       333710   Dunham, I. et.al.   Plus   7230314-7230476       333717   Dunham, I. et.al.   Plus   7308714-7308815       333727   Dunham, I. et.al.   Plus   7373219-7373311       333785   Dunham, I. et.al.   Plus   7775317-7775415       333791   Dunham, I. et.al.   Plus   7795972-7796082       333859   Dunham, I. et.al.   Plus   8041203-8041359       333875   Dunham, I. et.al.   Plus   8135505-8136179       333879   Dunham, I. et.al.   Plus   8146919-8147062       333891   Dunham, I. et.al.   Plus   8156437-8156709       333918   Dunham, I. et.al.   Plus   8307124-8307215       333929   Dunham, I. et.al.   Plus   8479486-8479580       333932   Dunham, I. et.al.   Plus   8489124-8489205       333983   Dunham, I. et.al.   Plus   8813593-8813668       333987   Dunham, I. et.al.   Plus   8824245-8824376       333997   Dunham, I. et.al.   Plus   8866668-8867255       334010   Dunham, I. et.al.   Plus   8996696-8998236       334015   Dunham, I. et.al.   Plus   9055452-9055595       334017   Dunham, I. et.al.   Plus   9139516-9139634       334026   Dunham, I. et.al.   Plus   9196549-9196681       334030   Dunham, I. et.al.   Plus   9288463-9288782       334044   Dunham, I. et.al.   Plus   9373898-9374065       334047   Dunham, I. et.al.   Plus   9428152-9428211       334055   Dunham, I. et.al.   Plus   9662077-9662270       334063   Dunham, I. et.al.   Plus   9731991-9732085       334066   Dunham, I. et.al.   Plus   9739568-9739680       334068   Dunham, I. et.al.   Plus   9746279-9746477       334076   Dunham, I. et.al.   Plus   9801613-9801693       334091   Dunham, I. et.al.   Plus   9872327-9872527       334106   Dunham, I. et.al.   Plus   10261155-10261841       334109   Dunham, I. et.al.   Plus   10267679-10267864       334111   Dunham, I. et.al.   Plus   10279365-10279531       334115   Dunham, I. et.al.   Plus   10316414-10316608       334118   Dunham, I. et.al.   Plus   10344273-10344384       334120   Dunham, I. et.al.   Plus   10402389-10403196       334135   Dunham, I. et.al.   Plus   10457085-10457183       334235   Dunham, I. et.al.   Plus   12983601-12983703       334239   Dunham, I. et.al.   Plus   13056569-13056693       334244   Dunham, I. et.al.   Plus   13159198-13159302       334257   Dunham, I. et.al.   Plus   13213243-13213429       334260   Dunham, I. et.al.   Plus   13223819-13223968       334298   Dunham, I. et.al.   Plus   13424763-13425914       334342   Dunham, I. et.al.   Plus   13646844-13646980       334354   Dunham, I. et.al.   Plus   13702598-13702747       334430   Dunham, I. et.al.   Plus   14269664-14270102       334435   Dunham, I. et.al.   Plus   14275597-14275689       334451   Dunham, I. et.al.   Plus   14315572-14315741       334504   Dunham, I. et.al.   Plus   14510206-14510398       334510   Dunham, I. et.al.   Plus   14522303-14522418       334518   Dunham, I. et.al.   Plus   14630584-14630669       334525   Dunham, I. et.al.   Plus   14781066-14781137       334528   Dunham, I. et.al.   Plus   14787558-14787675       334529   Dunham, I. et.al.   Plus   14788825-14788971       334565   Dunham, I. et.al.   Plus   14989033-14989353       334568   Dunham, I. et.al.   Plus   14992698-14993210       334590   Dunham, I. et.al.   Plus   15033247-15033753       334612   Dunham, I. et.al.   Plus   15170470-15170535       334626   Dunham, I. et.al.   Plus   15299954-15300077       334661   Dunham, I. et.al.   Plus   15477716-15477786       334664   Dunham, I. et.al.   Plus   15501941-15502119       334666   Dunham, I. et.al.   Plus   15504203-15504279       334676   Dunham, I. et.al.   Plus   15516334-15516412       334677   Dunham, I. et.al.   Plus   15517449-15517560       334719   Dunham, I. et.al.   Plus   15778859-15779026       334730   Dunham, I. et.al.   Plus   15967830-15967934       334797   Dunham, I. et.al.   Plus   16383231-16383458       334819   Dunham, I. et.al.   Plus   16758514-16758711       334855   Dunham, I. et.al.   Plus   18402556-18402735       334900   Dunham, I. et.al.   Plus   19315678-19315743       334906   Dunham, I. et.al.   Plus   19323493-19323590       334907   Dunham, I. et.al.   Plus   19336829-19336938       334914   Dunham, I. et.al.   Plus   19495158-19495275       334915   Dunham, I. et.al.   Plus   19505267-19506101       334935   Dunham, I. et.al.   Plus   20108247-20108373       335019   Dunham, I. et.al.   Plus   20689525-20689582       335036   Dunham, I. et.al.   Plus   20755250-20756375       335049   Dunham, I. et.al.   Plus   20877184-20877309       335081   Dunham, I. et.al.   Plus   21113871-21113937       335131   Dunham, I. et.al.   Plus   21449834-21450003       335157   Dunham, I. et.al.   Plus   21543302-21544341       335163   Dunham, I. et.al.   Plus   21583508-21583655       335174   Dunham, I. et.al.   Plus   21631301-21631447       335180   Dunham, I. et.al.   Plus   21641226-21641603       335188   Dunham, I. et.al.   Plus   21669118-21669328       335189   Dunham, I. et.al.   Plus   21673403-21673472       335193   Dunham, I. et.al.   Plus   21692208-21692362       335200   Dunham, I. et.al.   Plus   21743499-21743881       335201   Dunham, I. et.al.   Plus   21745249-21745664       335284   Dunham, I. et.al.   Plus   22272583-22272712       335311   Dunham, I. et.al.   Plus   22501602-22501676       335320   Dunham, I. et.al.   Plus   22542132-22542246       335371   Dunham, I. et.al.   Plus   22849529-22849808       335377   Dunham, I. et.al.   Plus   22869909-22870188       335421   Dunham, I. et.al.   Plus   23250433-23250498       335448   Dunham, I. et.al.   Plus   23477532-23477831       335451   Dunham, I. et.al.   Plus   23480611-23480711       335455   Dunham, I. et.al.   Plus   23486127-23486216       335468   Dunham, I. et.al.   Plus   23787246-23787367       335470   Dunham, I. et.al.   Plus   23812877-23813365       335482   Dunham, I. et.al.   Plus   24087956-24088114       335485   Dunham, I. et.al.   Plus   24098953-24099123       335517   Dunham, I. et.al.   Plus   24226461-24226531       335536   Dunham, I. et.al.   Plus   24498783-24499762       335565   Dunham, I. et.al.   Plus   24881886-24882470       335585   Dunham, I. et.al.   Plus   24988240-24988405       335587   Dunham, I. et.al.   Plus   24991457-24991618       335593   Dunham, I. et.al.   Plus   25037253-25037370       335634   Dunham, I. et.al.   Plus   25163837-25164042       335651   Dunham, I. et.al.   Plus   25317560-25317696       335652   Dunham, I. et.al.   Plus   25325625-25325883       335667   Dunham, I. et.al.   Plus   25345735-25345856       335687   Dunham, I. et.al.   Plus   25445952-25446064       335690   Dunham, I. et.al.   Plus   25455442-25455625       335692   Dunham, I. et.al.   Plus   25468557-25468725       335693   Dunham, I. et.al.   Plus   25471363-25471524       335700   Dunham, I. et.al.   Plus   25512222-25512890       335720   Dunham, I. et.al.   Plus   25596542-25596646       335721   Dunham, I. et.al.   Plus   25599118-25599228       335733   Dunham, I. et.al.   Plus   25686486-25686626       335739   Dunham, I. et.al.   Plus   25698550-25698826       335745   Dunham, I. et.al.   Plus   25718164-25718332       335747   Dunham, I. et.al.   Plus   25723304-25723494       335783   Dunham, I. et.al.   Plus   25941882-25942040       335968   Dunham, I. et.al.   Plus   27743843-27744029       335971   Dunham, I. et.al.   Plus   27752808-27753017       335975   Dunham, I. et.al.   Plus   27801321-27801391       335993   Dunham, I. et.al.   Plus   28006396-28006571       335998   Dunham, I. et.al.   Plus   28026247-28026356       336011   Dunham, I. et.al.   Plus   28570760-28570900       336035   Dunham, I. et.al.   Plus   29016748-29017410       336049   Dunham, I. et.al.   Plus   29124451-29124606       336055   Dunham, I. et.al.   Plus   29166352-29166573       336072   Dunham, I. et.al.   Plus   29269409-29269575       336075   Dunham, I. et.al.   Plus   29343938-29344050       336081   Dunham, I. et.al.   Plus   29372270-29372407       336083   Dunham, I. et.al.   Plus   29379738-29379881       336084   Dunham, I. et.al.   Plus   29380664-29380792       336086   Dunham, I. et.al.   Plus   29385594-29385713       336087   Dunham, I. et.al.   Plus   29387122-29387253       336088   Dunham, I. et.al.   Plus   29389001-29389124       336089   Dunham, I. et.al.   Plus   29401421-29401625       336090   Dunham, I. et.al.   Plus   29413020-29413162       336091   Dunham, I. et.al.   Plus   29415486-29415617       336092   Dunham, I. et.al.   Plus   29438816-29438948       336094   Dunham, I. et.al.   Plus   29567934-29568099       336102   Dunham, I. et.al.   Plus   29681500-29681687       336124   Dunham, I. et.al.   Plus   30053441-30053500       336125   Dunham, I. et.al.   Plus   30056541-30056622       336127   Dunham, I. et.al.   Plus   30058870-30059029       336128   Dunham, I. et.al.   Plus   30059294-30059367       336171   Dunham, I. et.al.   Plus   30223877-30224048       336214   Dunham, I. et.al.   Plus   30561988-30562044       336306   Dunham, I. et.al.   Plus   33172949-33173281       336316   Dunham, I. et.al.   Plus   33338776-33338919       336333   Dunham, I. et.al.   Plus   33673947-33677345       336387   Dunham, I. et.al.   Plus   34013939-34014124       336442   Dunham, I. et.al.   Plus   34187937-34188081       336481   Dunham, I. et.al.   Plus   34231611-34231720       336489   Dunham, I. et.al.   Plus   34239511-34239619       336498   Dunham, I. et.al.   Plus   34267340-34267424       336502   Dunham, I. et.al.   Plus   34268953-34269083       336516   Dunham, I. et.al.   Plus   34296068-34296249       336548   Dunham, I. et.al.   Plus   34353881-34354826       336590   Dunham, I. et.al.   Plus   2569428-2570275       336593   Dunham, I. et.al.   Plus   4617967-4618783       336606   Dunham, I. et.al.   Plus   16170215-16170415       336623   Dunham, I. et.al.   Plus   167287-167616       336632   Dunham, I. et.al.   Plus   983890-985529       336633   Dunham, I. et.al.   Plus   985591-986221       336634   Dunham, I. et.al.   Plus   986296-986670       336635   Dunham, I. et.al.   Plus   987908-988364       336637   Dunham, I. et.al.   Plus   989276-990813       336638   Dunham, I. et.al.   Plus   991906-993240       336654   Dunham, I. et.al.   Plus   1588782-1588858       336665   Dunham, I. et.al.   Plus   2007241-2007363       336695   Dunham, I. et.al.   Plus   2464609-2464739       336705   Dunham, I. et.al.   Plus   2817668-2817723       336751   Dunham, I. et.al.   Plus   4499629-4499739       336753   Dunham, I. et.al.   Plus   4509509-4509601       336757   Dunham, I. et.al.   Plus   4541167-4541466       336759   Dunham, I. et.al.   Plus   4560526-4560699       336808   Dunham, I. et.al.   Plus   6251639-6251761       336813   Dunham, I. et.al.   Plus   6436416-6436719       336827   Dunham, I. et.al.   Plus   6773762-6774057       336833   Dunham, I. et.al.   Plus   6856506-6856634       336836   Dunham, I. et.al.   Plus   7077262-7077326       336878   Dunham, I. et.al.   Plus   9200300-9200399       336898   Dunham, I. et.al.   Plus   10138365-10138458       336917   Dunham, I. et.al.   Plus   11228329-11228403       336924   Dunham, I. et.al.   Plus   11525273-11525527       336934   Dunham, I. et.al.   Plus   11854506-11854792       336958   Dunham, I. et.al.   Plus   13203550-13203973       336968   Dunham, I. et.al.   Plus   13660250-13660530       336986   Dunham, I. et.al.   Plus   14785058-14785225       337032   Dunham, I. et.al.   Plus   16949229-16949306       337121   Dunham, I. et.al.   Plus   22050289-22050370       337132   Dunham, I. et.al.   Plus   22255234-22255437       337168   Dunham, I. et.al.   Plus   23503596-23504240       337170   Dunham, I. et.al.   Plus   23533763-23534008       337172   Dunham, I. et.al.   Plus   23608358-23608526       337218   Dunham, I. et.al.   Plus   26126466-26126565       337219   Dunham, I. et.al.   Plus   26129629-26130053       337236   Dunham, I. et.al.   Plus   27114318-27114571       337238   Dunham, I. et.al.   Plus   27141465-27141776       337259   Dunham, I. et.al.   Plus   27674026-27674142       337291   Dunham, I. et.al.   Plus   28823308-28823412       337298   Dunham, I. et.al.   Plus   29002509-29002806       337304   Dunham, I. et.al.   Plus   29131691-29131823       337333   Dunham, I. et.al.   Plus   30281383-30281673       337338   Dunham, I. et.al.   Plus   30427592-30427775       337345   Dunham, I. et.al.   Plus   30649387-30649467       337355   Dunham, I. et.al.   Plus   30832838-30833042       337363   Dunham, I. et.al.   Plus   30942712-30942840       337396   Dunham, I. et.al.   Plus   31585902-31586067       337402   Dunham, I. et.al.   Plus   31691134-31691482       337403   Dunham, I. et.al.   Plus   31692319-31692611       337425   Dunham, I. et.al.   Plus   32072241-32072334       337426   Dunham, I. et.al.   Plus   32076190-32076349       337427   Dunham, I. et.al.   Plus   32078958-32079076       337435   Dunham, I. et.al.   Plus   32255716-32255844       337484   Dunham, I. et.al.   Plus   33238033-33238176       337489   Dunham, I. et.al.   Plus   33295724-33295872       337503   Dunham, I. et.al.   Plus   33385583-33385857       337504   Dunham, I. et.al.   Plus   33386053-33386236       337522   Dunham, I. et.al.   Plus   33963188-33963979       337544   Dunham, I. et.al.   Plus   34268412-34268495       337548   Dunham, I. et.al.   Plus   34472882-34472957       337562   Dunham, I. et.al.   Plus   278105-278281       337564   Dunham, I. et.al.   Plus   285643-285788       337586   Dunham, I. et.al.   Plus   952102-952250       337628   Dunham, I. et.al.   Plus   2013838-2014032       337657   Dunham, I. et.al.   Plus   2844851-2845055       337685   Dunham, I. et.al.   Plus   3547161-3547245       337695   Dunham, I. et.al.   Plus   3609670-3609808       337697   Dunham, I. et.al.   Plus   3644971-3645195       337756   Dunham, I. et.al.   Plus   3975015-3975172       337781   Dunham, I. et.al.   Plus   4116049-4116265       337797   Dunham, I. et.al.   Plus   4325712-4325811       337835   Dunham, I. et.al.   Plus   4792299-4792423       337843   Dunham, I. et.al.   Plus   4984966-4985082       337865   Dunham, I. et.al.   Plus   5377705-5377861       337870   Dunham, I. et.al.   Plus   5442516-5442636       337904   Dunham, I. et.al.   Plus   5685819-5686012       337918   Dunham, I. et.al.   Plus   6031241-6031358       337930   Dunham, I. et.al.   Plus   6393566-6393692       337947   Dunham, I. et.al.   Plus   6675643-6675781       337951   Dunham, I. et.al.   Plus   6766321-6766382       337954   Dunham, I. et.al.   Plus   6831483-6831620       337964   Dunham, I. et.al.   Plus   7032720-7032802       338043   Dunham, I. et.al.   Plus   8222138-8222430       338054   Dunham, I. et.al.   Plus   8429258-8429382       338062   Dunham, I. et.al.   Plus   8578852-4579012       338080   Dunham, I. et.al.   Plus   9212114-9212220       338090   Dunham, I. et.al.   Plus   9488619-9488858       338096   Dunham, I. et.al.   Plus   9698397-9698469       338120   Dunham, I. et.al.   Plus   10765673-10765820       338123   Dunham, I. et.al.   Plus   10615824-10815886       338124   Dunham, I. et.al.   Plus   10860311-10860471       338177   Dunham, I. et.al.   Plus   12781530-12781724       338239   Dunham, I. et.al.   Plus   14669918-14670016       338278   Dunham, I. et.al.   Plus   16168714-16168840       338280   Dunham, I. et.al.   Plus   16171884-16172039       338326   Dunham, I. et.al.   Plus   17358806-17358964       338336   Dunham, I. et.al.   Plus   17453324-17453448       338344   Dunham, I. et.al.   Plus   17780512-17780623       338411   Dunham, I. et.al.   Plus   19299273-19299522       338412   Dunham, I. et.al.   Plus   19340661-19340737       338491   Dunham, I. et.al.   Plus   21168430-21168556       338514   Dunham, I. et.al.   Plus   21379420-21379655       338516   Dunham, I. et.al.   Plus   21382180-21382383       338521   Dunham, I. et.al.   Plus   21471358-21471476       338522   Dunham, I. et.al.   Plus   21471617-21471711       338526   Dunham, I. et.al.   Plus   21551136-21551250       338527   Dunham, I. et.al.   Plus   21552237-21553280       338529   Dunham, I. et.al.   Plus   21635616-21635867       338579   Dunham, I. et.al.   Plus   22774968-22775132       338596   Dunham, I. et.al.   Plus   23078273-23078348       338648   Dunham, I. et.al.   Plus   24091259-24091434       338679   Dunham, I. et.al.   Plus   24684836-24684940       338703   Dunham, I. et.al.   Plus   25219881-25220046       338705   Dunham, I. et.al.   Plus   25231397-25231551       338747   Dunham, I. et.al.   Plus   26336372-26336460       338770   Dunham, I. et.al.   Plus   26784513-26784714       338809   Dunham, I. et.al.   Plus   27271920-27272000       338830   Dunham, I. et.al.   Plus   27759923-27760055       338880   Dunham, I. et.al.   Plus   28420713-28420826       338895   Dunham, I. et.al.   Plus   28598893-28599135       338896   Dunham, I. et.al.   Plus   28618487-28618552       338911   Dunham, I. et.al.   Plus   28804184-28804445       338925   Dunham, I. et.al.   Plus   28883892-28884036       338952   Dunham, I. et.al.   Plus   29418831-29418968       338959   Dunham, I. et.al.   Plus   29478431-29478589       338970   Dunham, I. et.al.   Plus   29645468-29645613       339081   Dunham, I. et.al.   Plus   30927871-30928080       339116   Dunham, I. et.al.   Plus   31462304-31462382       339164   Dunham, I. et.al.   Plus   32207441-32207802       339246   Dunham, I. et.al.   Plus   32844518-32844586       339271   Dunham, I. et.al.   Plus   32999935-33000078       339304   Dunham, I. et.al.   Plus   33323712-33323821       339309   Dunham, I. et.al.   Plus   33366900-33367198       339312   Dunham, I. et.al.   Plus   33378992-33379172       339356   Dunham, I. et.al.   Plus   33573387-33573517       339367   Dunham, I. et.al.   Plus   33575210-33575416       339360   Dunham, I. et.al.   Plus   33579433-33579593       339384   Dunham, I. et.al.   Plus   33950591-33950697       339413   Dunham, I. et.al.   Plus   34268734-34268875       339419   Dunham, I. et.al.   Plus   34359680-34359777       332854   Dunham, I. et.al.   Minus   1283811-1283053       332859   Dunham, I. et.al.   Minus   1358943-1358861       332896   Dunham, I. et.al.   Minus   1631841-1631422       332995   Dunham, I. et.al.   Minus   2708847-2708685       333014   Dunham, I. et.al.   Minus   2772479-2772387       333043   Dunham, I. et.al.   Minus   2920906-2920781       333054   Dunham, I. et.al.   Minus   2995314-2995219       333069   Dunham, I. et.al.   Minus   3040771-3040661       333074   Dunham, I. et.al.   Minus   3054171-3054008       333101   Dunham, I. et.al.   Minus   3208966-3208908       333140   Dunham, I. et.al.   Minus   3377220-3376309       333142   Dunham, I. et.al.   Minus   3474264-3474145       333175   Dunham, I. et.al.   Minus   3768113-3768051       333216   Dunham, I. et.al.   Minus   3967627-3967512       333219   Dunham, I. et.al.   Minus   3968531-3968423       333220   Dunham, I. et.al.   Minus   3969363-3968789       333240   Dunham, I. et.al.   Minus   4100495-4100281       333242   Dunham, I. et.al.   Minus   4104544-4104259       333251   Dunham, I. et.al.   Minus   4168970-4168870       333252   Dunham, I. et.al.   Minus   4172550-4172390       333257   Dunham, I. et.al.   Minus   4300724-4300578       333258   Dunham, I. et.al.   Minus   4301348-4301269       333271   Dunham, I. et.al.   Minus   4377786-4377589       333294   Dunham, I. et.al.   Minus   4538728-4538642       333296   Dunham, I. et.al.   Minus   4550766-4550644       333312   Dunham, I. et.al.   Minus   4638794-4638635       333313   Dunham, I. et.al.   Minus   4639397-4639277       333323   Dunham, I. et.al.   Minus   4655333-4655166       333329   Dunham, I. et.al.   Minus   4661779-4661672       333339   Dunham, I. et.al.   Minus   4679691-4679610       333346   Dunham, I. et.al.   Minus   4704564-4704466       333355   Dunham, I. et.al.   Minus   4727555-4727460       333408   Dunham, I. et.al.   Minus   4936879-4936661       333423   Dunham, I. et.al.   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Minus   30169370-30169185       336177   Dunham, I. et.al.   Minus   30306638-30303284       336198   Dunham, I. et.al.   Minus   30459668-30459460       336199   Dunham, I. et.al.   Minus   30461245-30461040       336200   Dunham, I. et.al.   Minus   30462971-30462895       336202   Dunham, I. et.al.   Minus   30468933-30466781       336203   Dunham, I. et.al.   Minus   30470796-30470653       336227   Dunham, I. et.al.   Minus   30902014-30901946       336231   Dunham, I. et.al.   Minus   30967656-30967471       336232   Dunham, I. et.al.   Minus   30977707-30977645       336238   Dunham, I. et.al.   Minus   31160083-31159959       336243   Dunham, I. et.al.   Minus   31402237-31402104       336246   Dunham, I. et.al.   Minus   31425669-31425253       336279   Dunham, I. et.al.   Minus   32103203-32102860       336280   Dunham, I. et.al.   Minus   32103588-32103497       336294   Dunham, I. et.al.   Minus   32946997-32946890       336295   Dunham, I. et.al.   Minus   32950291-32950162       336328   Dunham, I. et.al.   Minus   33584461-33584201       336347   Dunham, I. et.al.   Minus   33843218-33843104       336351   Dunham, I. et.al.   Minus   33865890-33865681       336397   Dunham, I. et.al.   Minus   34021504-34021389       336400   Dunham, I. et.al.   Minus   34023437-34023298       336402   Dunham, I. et.al.   Minus   34024090-34023981       336406   Dunham, I. et.al.   Minus   34030774-34030564       336417   Dunham, I. et.al.   Minus   34047771-34047675       336455   Dunham, I. et.al.   Minus   34209155-34209018       336463   Dunham, I. et.al.   Minus   34212236-34211968       336479   Dunham, I. et.al.   Minus   34218224-34218139       336510   Dunham, I. et.al.   Minus   34277046-34276928       336538   Dunham, I. et.al.   Minus   34329270-34329189       336584   Dunham, I. et.al.   Minus   34516568-34516468       336599   Dunham, I. et.al.   Minus   11736500-11734418       336615   Dunham, I. et.al.   Minus   26020622-26016546       336616   Dunham, I. et.al.   Minus   26021027-26020848       336618   Dunham, I. et.al.   Minus   25799-25612       336645   Dunham, I. et.al.   Minus   1351268-1351168       336653   Dunham, I. et.al.   Minus   1568327-1568216       336657   Dunham, I. et.al.   Minus   1705497-1705415       336717   Dunham, I. et.al.   Minus   3297417-3297352       336772   Dunham, I. et.al.   Minus   5129939-5129785       336795   Dunham, I. et.al.   Minus   5681580-5681460       336796   Dunham, I. et.al.   Minus   5683253-5683016       336854   Dunham, I. et.al.   Minus   7884839-7884767       336858   Dunham, I. et.al.   Minus   8200946-8200789       336882   Dunham, I. et.al.   Minus   8394593-8394369       336863   Dunham, I. et.al.   Minus   8396673-8396425       336883   Dunham, I. et.al.   Minus   9322767-9322554       336908   Dunham, I. et.al.   Minus   10791347-10791256       336927   Dunham, I. et.al.   Minus   11548111-11547937       336929   Dunham, I. et.al.   Minus   11603040-11602908       336978   Dunham, I. et.al.   Minus   14241223-14241030       336981   Dunham, I. et.al.   Minus   14478638-14478472       336984   Dunham, I. et.al.   Minus   14725450-14725309       336994   Dunham, I. et.al.   Minus   15104752-15104656       336999   Dunham, I. et.al.   Minus   15389579-15388897       337011   Dunham, I. et.al.   Minus   16106423-16106080       337023   Dunham, I. et.al.   Minus   16346174-16346065       337069   Dunham, I. et.al.   Minus   19014379-19014222       337092   Dunham, I. et.al.   Minus   20140132-20139980       337093   Dunham, I. et.al.   Minus   20145693-20145570       337094   Dunham, I. et.al.   Minus   20146915-20146778       337097   Dunham, I. et.al.   Minus   20498648-20497686       337100   Dunham, I. et.al.   Minus   20543630-20543751       337114   Dunham, I. et.al.   Minus   21328259-21328050       337203   Dunham, I. et.al.   Minus   25349286-25349156       337204   Dunham, I. et.al.   Minus   25419024-25418931       337225   Dunham, I. et.al.   Minus   26607638-26607468       337244   Dunham, I. et.al.   Minus   27362048-27361952       337279   Dunham, I. et.al.   Minus   28430185-28430033       337289   Dunham, I. et.al.   Minus   28756246-28756163       337316   Dunham, I. et.al.   Minus   29657129-29656997       337431   Dunham, I. et.al.   Minus   32110529-32110475       337432   Dunham, I. et.al.   Minus   32199134-32198922       337445   Dunham, I. et.al.   Minus   32292380-32292228       337451   Dunham, I. et.al.   Minus   32408680-32408576       337452   Dunham, I. et.al.   Minus   32415187-32415117       337455   Dunham, I. et.al.   Minus   32434517-32434425       337456   Dunham, I. et.al.   Minus   32438887-32438828       337513   Dunham, I. et.al.   Minus   33478692-33478562       337514   Dunham, I. et.al.   Minus   33484408-33484339       337517   Dunham, I. et.al.   Minus   33795568-33795385       337590   Dunham, I. et.al.   Minus   982397-982246       337592   Dunham, I. et.al.   Minus   1007791-1007634       337604   Dunham, I. et.al.   Minus   1329838-1329759       337606   Dunham, I. et.al.   Minus   1346786-1346617       337612   Dunham, I. et.al.   Minus   1570235-1570142       337645   Dunham, I. et.al.   Minus   5141462-5141329       337704   Dunham, I. et.al.   Minus   3658670-3658545       337706   Dunham, I. et.al.   Minus   3672056-3671922       337760   Dunham, I. et.al.   Minus   4008389-4008037       337768   Dunham, I. et.al.   Minus   4050134-4049973       337771   Dunham, I. et.al.   Minus   4060797-4060707       337778   Dunham, I. et.al.   Minus   4087301-4087157       337787   Dunham, I. et.al.   Minus   4135097-4135025       337816   Dunham, I. et.al.   Minus   4523203-4523090       337821   Dunham, I. et.al.   Minus   4538189-4538075       337848   Dunham, I. et.al.   Minus   5053964-5053829       337911   Dunham, I. et.al.   Minus   5866504-5866154       337913   Dunham, I. et.al.   Minus   6149843-6149786       337974   Dunham, I. et.al.   Minus   7153401-7153085       337984   Dunham, I. et.al.   Minus   7282160-7282020       338069   Dunham, I. et.al.   Minus   8728655-8728580       338087   Dunham, I. et.al.   Minus   9362067-9361878       338113   Dunham, I. et.al.   Minus   10481242-10481089       338132   Dunham, I. et.al.   Minus   10989617-10989530       338140   Dunham, I. et.al.   Minus   11237977-11237876       338151   Dunham, I. et.al.   Minus   11519629-11519501       338221   Dunham, I. et.al.   Minus   14183649-14183568       338223   Dunham, I. et.al.   Minus   14287001-14286830       338235   Dunham, I. et.al.   Minus   14484254-14484179       338271   Dunham, I. et.al.   Minus   16048151-16047985       338285   Dunham, I. et.al.   Minus   16276030-16274895       338306   Dunham, I. et.al.   Minus   16966519-16966247       338325   Dunham, I. et.al.   Minus   17241596-17241507       338368   Dunham, I. et.al.   Minus   18272087-18272025       338381   Dunham, I. et.al.   Minus   18534404-18534234       338431   Dunham, I. et.al.   Minus   19747608-19747496       338450   Dunham, I. et.al.   Minus   20172384-20172200       338451   Dunham, I. et.al.   Minus   20174286-20174193       338486   Dunham, I. et.al.   Minus   21063152-21063049       338508   Dunham, I. et.al.   Minus   21308161-21307923       338576   Dunham, I. et.al.   Minus   22676619-22676368       338591   Dunham, I. et.al.   Minus   22959271-22959182       338593   Dunham, I. et.al.   Minus   22992718-22992531       338594   Dunham, I. et.al.   Minus   23026144-23026029       338668   Dunham, I. et.al.   Minus   24500606-24500442       338686   Dunham, I. et.al.   Minus   24836463-24838246       338725   Dunham, I. et.al.   Minus   25904148-25904017       338819   Dunham, I. et.al.   Minus   27539222-27539058       338829   Dunham, I. et.al.   Minus   27739328-27739163       338843   Dunham, I. et.al.   Minus   27899321-27899045       338934   Dunham, I. et.al.   Minus   29036147-29036048       338976   Dunham, I. et.al.   Minus   29867484-29867259       338990   Dunham, I. et.al.   Minus   30019967-30019837       339019   Dunham, I. et.al.   Minus   30498278-30498118       339032   Dunham, I. et.al.   Minus   30613407-30613275       339033   Dunham, I. et.al.   Minus   30621102-30620830       339037   Dunham, I. et.al.   Minus   30634104-30633988       339044   Dunham, I. et.al.   Minus   30721853-30721740       339071   Dunham, I. et.al.   Minus   30885702-30885511       339127   Dunham, I. et.al.   Minus   31688232-31688072       339130   Dunham, I. et.al.   Minus   31743961-31743767       339181   Dunham, I. et.al.   Minus   32321697-32321571       339188   Dunham, I. et.al.   Minus   32347554-32347250       339193   Dunham, I. et.al.   Minus   32415060-32414928       339196   Dunham, I. et.al.   Minus   32431422-32431097       339208   Dunham, I. et.al.   Minus   32491714-32491657       339213   Dunham, I. et.al.   Minus   32496590-32496440       339215   Dunham, I. et.al.   Minus   32502559-32502383       339220   Dunham, I. et.al.   Minus   32519184-32519081       339230   Dunham, I. et.al.   Minus   32729004-32728929       339251   Dunham, I. et.al.   Minus   32894314-32894216       339256   Dunham, I. et.al.   Minus   32926055-32925967       339266   Dunham, I. et.al.   Minus   32976148-32976041       339288   Dunham, I. et.al.   Minus   32984700-32984500       339280   Dunham, I. et.al.   Minus   33114230-33114010       339340   Dunham, I. et.al.   Minus   33485220-33485144       339342   Dunham, I. et.al.   Minus   33494677-33494541       339344   Dunham, I. et.al.   Minus   33503675-33503520       339363   Dunham, I. et.al.   Minus   33589964-33589665       339365   Dunham, I. et.al.   Minus   33641615-33641446       339401   Dunham, I. et.al.   Minus   34045393-34045138       339424   Dunham, I. et.al.   Minus   34392464-34392311       339435   Dunham, I. et.al.   Minus   34538987-34538876       337884       337885       337895       337898       329611   3962478   Minus   11780-11875       329496   3983518   Plus   13570-13686       325310   5866864   Minus   17256-17357       325320   5866670   Minus   33200-33646       325338   5666883   Minus   62747-62928       325271   5866901   Plus   87318-87378       325285   5866903   Plus   107772-107864       325289   5866903   Minus   129715-129877       325300   5866908   Minus   7940-8059       325304   5866910   Minus   37466-37884       329630   6729060   Minus   167326-167511       325369   5866920   Minus   1018736-1018830       325359   5866920   Plus   392668-392781       325408   5866921   Plus   599118-599289       325409   5866921   Plus   599438-599655       325410   5866921   Plus   615477-615580       325393   5866921   Minus   350513-350691       325396   5866921   Plus   476868-477200       325433   5866936   Minus   480706-480826       325448   5866941   Minus   392834-392982       325464   5866947   Plus   323995-324279       325480   5866957   Plus   20558-21112       325482   5866957   Plus   47957-48078       325510   5866974   Plus   219958-220917       325524   5866981   Minus   117837-117997       325513   6017035   Minus   34295-34490       325519   6017036   Minus   186804-186915       325571   6552439   Minus   184952-185135       329638   3779004   Minus   4636-5127       325623   5867000   Plus   84366-84472       325636   5867002   Minus   149928-150033       325677   5867017   Minus   58414-58518       325691   5867021   Plus   65467-65629       325690   5867021   Plus   7391-7530       325702   5867028   Plus   139925-140061       325703   5867028   Plus   155806-156098       325790   6381957   Minus   105385-105524       325783   6456780   Plus   102815-102957       325695   6552446   Minus   199599-199778       325726   6552447   Plus   154262-154623       325742   6552448   Minus   38225-38306       325760   6552449   Plus   343394-343549       325801   6552451   Plus   49269-49542       325803   6552451   Plus   53355-53558       325649   6588011   Minus   215659-215815       325710   6682473   Plus   204538-204822       325712   6682473   Plus   208541-208926       325755   6682474   Plus   406603-407037       325751   6682474   Plus   130437-130520       325763   6682475   Minus   327530-327910       325791   6682476   Plus   344059-344841       329782   5912597   Plus   123410-123499       329779   6002090   Minus   195353-195669       329760   6048280   Minus   51419-51528       329752   6065777   Plus   132916-133335       329737   6065779   Plus   70136-70236       329735   6065780   Plus   63923-64213       329719   6065785   Plus   46970-47762       329725   6065785   Plus   133747-133842       329705   6065790   Minus   63183-63724       329665   6272129   Plus   91791-91891       329793   6522661   Minus   96556-96698       329824   6630758   Minus   126072-126254       329839   6672062   Plus   34377-34537       329853   6682295   Plus   68945-69009       329870   6706435   Minus   5729-5870       329879   6466518   Minus   12266-12356       329902   6634760   Plus   106906-106984       325851   5867067   Minus   51751-51981       325886   5867087   Plus   194694-194915       325887   5867087   Plus   195052-195485       326005   5867112   Minus   7827-8117       325945   5867138   Minus   123079-124086       325953   5867140   Minus   4721-4901       325965   5867147   Plus   216364-216516       325966   5867147   Plus   217235-217356       325977   6249602   Plus   60638-60759       325835   6552452   Minus   81182-81414       329995   4567166   Minus   150014-150315       329948   5540101   Minus   134056-134261       329940   6165199   Minus   33718-33882       329921   6165205   Minus   33759-33891       330002   6623963   Plus   46097-46158       330021   6671889   Plus   120938-121032       326162   5867168   Minus   5870-6291       326070   5867175   Plus   132181-132731       326029   5867176   Minus   112558-112669       326033   5867178   Plus   37261-37333       326039   5867179   Minus   15157-15227       326122   5867194   Plus   144397-144683       326136   5867202   Minus   155973-156065       326194   5867213   Plus   75271-75522       326206   5867219   Plus   113881-115080       326218   5867226   Minus   259784-259920       326224   5867230   Plus   21528-21667       326240   5867260   Plus   94843-96127       326253   5867263   Minus   222216-222341       326249   5867263   Minus   80253-80323       326266   5867264   Plus   337993-338192       326304   5867277   Minus   367450-367559       326309   5867277   Plus   614150-614294       326310   5867277   Plus   621555-621698       326338   6056311   Minus   161972-162333       326343   6525295   Minus   2699-2777       326344   6525295   Minus   3207-3365       326073   6682495   Minus   248865-249009       330057   6478962   Plus   75145-75287       330058   6634847   Plus   100602-100963       330061   6721261   Plus   4254-4388       326539   5867307   Plus   198357-198504       326545   5867307   Plus   600850-601425       326549   5867307   Plus   698004-698069       326552   5867308   Minus   6988-7107       326554   5867308   Plus   16259-18271       326559   5867310   Plus   159233-159439       326577   5867317   Plus   215987-216127       326380   5867327   Plus   32474-32668       326412   5867362   Minus   9263-9436       326417   5867362   Plus   89132-89383       326418   5867365   Plus   23609-23745       326423   5867369   Minus   142311-142500       326458   5867400   Plus   128045-128147       326459   5867400   Plus   137590-138212       326506   5867435   Minus   9368-9509       326509   6682496   Plus   92406-92680       330112   6015238   Plus   32059-32163       330086   6015293   Plus   29518-29662       330080   6015314   Minus   4890-4972       330082   6015314   Plus   27158-27296       330064   6165044   Minus   5619-5696       330063   6165044   Minus    948-1025       330065   6165044   Minus   9876-9948       326646   5867562   Plus   100426-100608       326688   5867582   Plus   104875-105531       326708   5867593   Minus   39203-39310       326710   5867593   Minus   80204-80468       326746   5867611   Plus   129366-129565       326793   5867631   Plus   136295-136518       326603   6056312   Minus   50323-50575       326806   6469835   Plus   101628-102149       326783   6525298   Plus   196378-196863       326668   6552455   Plus   146726-146838       326725   6552456   Minus   223005-223125       326857   6552460   Minus   120142-120345       326763   6598307   Plus   239690-239902       326808   6682504   Minus   65107-65214       326874   6682507   Minus   4643-4888       326876   6682507   Minus   46203-46499       326884   6682511   Plus   33403-33479       326997   5867660   Minus   71389-72147       327009   5867654   Plus   933145-933266       327015   5867664   Plus   1030457-1030534       326942   6004446   Minus   88675-88785       326943   6004446   Minus   89242-89427       326957   6469836   Plus   37529-37694       327049   6531965   Minus   1924026-1924110       327051   6531965   Plus   2222592-2222717       327056   6531965   Plus   2374323-2374751       327059   6531965   Plus   2421032-2421799       327067   6531965   Minus   3726023-3726668       327089   6531965   Plus   5238983-5239187       327037   6531965   Minus   387854-388045       327123   6531971   Minus   23980-24340       327125   6531971   Plus   48884-48975       326981   6588016   Plus   105091-106038       330139   4210430   Plus   112089-112450       330153   4325335   Plus   146951-147475       330130   6002196   Minus   241903-241967       327203   5867447   Plus   36485-36577       327206   5867447   Plus   177855-178031       327259   5867454   Plus   87268-87438       327264   5867461   Plus   47014-47367       327273   5867466   Plus   73451-73549       327274   5867470   Minus   84027-84128       327277   5867473   Minus   165616-165715       327278   5867473   Minus   166350-166439       327289   5867481   Plus   49296-49536       327304   5867494   Plus   20664-20850       327315   5867508   Minus   78409-79245       327246   5867547   Plus   136212-136325       327155   5867549   Plus   90343-90876       327159   5867550   Minus   8219-8331       327334   5902477   Minus   142655-142745       327341   6017016   Minus   122906-123014       327185   6117805   Minus   3287-3451       327309   6456757   Minus   10219-10457       327263   6525274   Minus   153814-154920       327362   6552412   Minus   62459-62805       327413   5867750   Plus   101410-101508       327418   5867750   Minus   153453-153547       327430   5867754   Plus   1320-1403       327431   5867754   Plus   1853-1958       327472   5867775   Plus   74628-74937       327487   5867785   Minus   146220-146326       327379   5867795   Plus   1368-1820       327461   6004455   Plus   209031-209210       327532   6469818   Plus   71994-72137       330170   6648220   Plus   103280-103849       330166   6648220   Plus   86542-86867       327544   5867797   Minus   18105-18332       327564   5867811   Plus   13850-14018       327566   5867811   Plus   33383-33901       327581   5867825   Plus   5318-5434       327585   5867825   Plus   85660-85764       327605   6004463   Plus   199214-199579       327710   5867860   Minus   131012-131790       327610   5867868   Minus   174109-174278       327624   5867871   Minus   37699-37788       327641   5867890   Plus   13583-13702       327646   5867894   Minus   3043-3258       327614   6525283   Plus   3634-4001       327736   5867940   Minus   37781-37887       327739   5867942   Minus   182187-182548       327740   5867943   Plus   25716-26077       327743   5867944   Minus   155930-156098       327755   5867955   Minus   61969-62145       327772   5867964   Minus   26185-26285       327774   5867964   Minus   127659-127899       327823   5867968   Minus   170359-170433       327827   5867968   Minus   201918-202048       327833   5867968   Minus   303618-303732       327805   5867968   Plus   19952-20019       327809   5867968   Plus   54610-54761       327816   5867968   Minus   79202-79552       327790   5867977   Plus   19822-19985       327791   5867977   Plus   22491-22610       327793   5867979   Plus   18874-19254       327845   6531962   Plus   193402-193549       327846   6531962   Plus   195216-195373       330204   6013606   Plus   86663-86811       330189   6165182   Minus   26732-26991       330239   6671857   Plus   117484-118092       330266   6671885   Minus   129505-129832       330275   6671904   Plus   103585-103716       330280   6671910   Plus   2109-2377       330286   6671913   Minus   31050-31171       327999   5867994   Plus   94710-94841       328109   5868020   Minus   353895-354525       328098   5868020   Minus   261745-261920       328134   5868039   Plus   72354-72487       328171   5868071   Plus   101102-101224       328221   5868099   Minus   37489-37829       328224   5868101   Plus   105563-105832       328228   5868105   Minus   21488-21596       328236   5868117   Plus   13864-14371       327864   5868130   Plus   59139-59358       327888   5868149   Minus   51964-52120       327899   5868156   Minus   102288-102697       327925   5868172   Minus   118396-118490       327927   5868173   Plus   50989-51246       327937   5868192   Minus   33127-33485       327946   5868206   Plus   44102-44319       327982   5868216   Plus   30307-30527       327990   5868218   Minus   36225-36503       328015   5902482   Minus   477679-478113       328016   5902482   Minus   507572-508519       328025   5902482   Minus   931937-932171       328031   5902482   Plus   1176372-1177283       328053   5902482   Minus   2709850-2710010       328243   6056292   Plus    1-243       328271   6552415   Plus   39015-39098       328592   5868227   Minus   252407-252565       328570   5868231   Plus   89210-89816       328607   5868233   Minus   246798-246944       328620   5868241   Minus   15651-15788       328624   5868246   Minus   120666-120836       328791   5868309   Plus   171592-171929       328810   5868327   Plus   101730-101914       328820   5868330   Plus   90446-90602       328835   5868339   Plus   88053-88461       328282   5868353   Plus   72692-72819       328314   5868371   Minus   288397-288505       328328   5868375   Plus   169210-169407       328420   5868411   Plus   53612-53886       328428   5868417   Plus   13599-13780       328436   5868417   Plus   203760-203904       328444   5868420   Plus   65393-66103       328462   5868433   Plus   49649-49768       328467   5868434   Minus   15954-16073       328474   5868446   Minus   128777-128970       328484   5868454   Minus   21974-22140       328504   5868471   Plus   47064-47217       328506   5868471   Plus   60716-60830       328507   5868473   Minus   199637-199990       328544   5868486   Plus   145659-145829       328552   5868489   Plus   47328-47607       328557   5868489   Plus   138094-138161       328558   5868489   Plus   143648-144108       328276   6004471   Plus   13282-13450       328277   6004471   Minus   279901-280181       328662   6004473   Plus   1184773-1184855       328636   6004473   Plus   192484-192543       328803   6004475   Minus   291716-291948       328305   6004478   Minus   34730-34851       328569   6004480   Plus   232896-233243       328581   6006033   Minus   121249-121400       328582   6006033   Minus   134177-134282       328768   6017031   Minus   223741-224238       328770   6017031   Minus   363933-364166       328841   6381920   Minus   5214-5479       328851   6381923   Plus   2502-2606       328859   6381928   Plus   69045-69138       328860   6381928   Plus   83265-83366       328863   6381929   Minus   29313-29506       328868   6381930   Plus   112825-112993       328876   6525286   Plus   94053-94185       328886   6588003   Plus   31068-31429       328888   6588003   Minus   111901-111999       328936   5868500   Minus   1352202-1352259       328938   5868500   Plus   1522923-1522986       328971   6478806   Minus   23976-24105       330338   5457162   Plus   48406-48518       330327   5919194   Plus   121561-121683       330319   5932415   Plus   49095-50132       328974   5868520   Plus   31557-31668       328981   5868527   Minus   105677-105764       328989   5868535   Plus   182088-182198       330363   3126882   Minus   61838-61901       330370   6580495   Plus   10826-11669       329041   5868564   Plus   141592-141785       329078   5868597   Plus   326798-326860       329097   5868624   Plus   12002-12170       329107   5868626   Plus   101063-101190       329114   5868650   Minus   23792-23910       329116   5868650   Minus   43389-43493       329164   5868691   Plus   62305-62517       329187   5868713   Plus   29909-30175       329201   5868718   Plus   79266-79539       329221   5868727   Minus   105837-105894       329246   5868732   Minus   250541-250792       329254   5868733   Plus   4133-4214       329326   5868806   Plus   155884-155992       329330   5868806   Minus   340278-340403       329382   5868868   Plus   41401-41655       329384   5868869   Minus   116524-116662       329386   6004484   Plus   160502-161110       329140   6017060   Plus   290842-290905       329182   6056331   Minus   662206-663423       329018   6249620   Plus   103950-104034       329319   6381976   Plus   721390-721470       329392   6478815   Plus   109786-109854       329029   6525302   Plus   281445-282490       329401   6682544   Plus   21342-24014       329406   6682547   Plus   47249-47395       329411   6682549   Minus   84558-84835       329429   5868882   Minus   97008-97091       329436   5868883   Plus   230265-230528       329464   6456788   Minus   4437-4538                       #genomic sequence source used for prediction. Nucleotide locations of each predicted exon are also listed.                                             
     [0349]               TABLE 21                          310 GENES UP-REGULATED IN COLON CANCER DERIVED LIVER       METASTASES COMPARED TO NORMAL COLON TISSUE                                 Pkey   ExAccn   UnigeneID   Unigene Title   R1                                         446619   AU076643   Hs.313   secreted phosphoprotein 1 (osteopontin,   26.72       431958   X63629   Hs.2877   cadherin 3, type 1, P-cadherin (placenta   16.36       409041   AB033025   Hs.50081   KIAA1199 protein   13.94       444381   BE387335   Hs.283713   ESTs, Weakly similar to S64054 hypotheti   13.90       432314   AA533447   Hs.312989   ESTs   12.24       428330   L22524   Hs.2256   matrix metalloproteinase 7 (matrilysin,   11.60       443162   T49951   Hs.9029   DKFZP434G032 protein   9.52       436385   BE551618   Hs.144097   ESTs   9.20       418662   AI801098   Hs.151500   ESTs   9.00       433312   AI241331   Hs.131765   ESTs, Moderately similar to I38937 DNA/R   8.90       412093   BE242691   Hs.14947   ESTs   8.74       442369   AI565071   Hs.159983   ESTs   8.40       426101   AL049987   Hs.166361     Homo sapiens  mRNA; cDNA DKFZp564F112 (fr   8.39       435937   AA830893   Hs.119769   ESTs   8.22       452281   T93500   Hs.28792     Homo sapiens  cDNA FLJ11041 fis, clone PL   8.22       432572   AI660840   Hs.191202   ESTs, Weakly similar to ALUE_HUMAN !!!!   7.96       440524   R71264   Hs.16798   ESTs   7.94       424878   H57111   Hs.221132   ESTs   7.88       430433   AA478883   Hs.273766   ESTs   7.82       410245   C17908   Hs.194125   ESTs   7.78       417315   AI080042   Hs.336901   ribosomal protein S24   7.76       430665   BE350122   Hs.157367   ESTs, Weakly similar to I78885 serine/th   7.76       432435   BE218886   Hs.282070   ESTs   7.74       426818   AA554827   Hs.289115   DKFZp434A0131 protein   7.58       419145   N99638       gb: za39g11.r1 Soares fetal liver spleen   7.56       444838   AV651680   Hs.208558   ESTs   7.54       428046   AW812795   Hs.155381   ESTs, Moderately similar to I38022 hypot   7.48       446682   AW205632   Hs.211198   ESTs   7.26       421221   AW276914   Hs.326714     Homo sapiens  clone IMAGE: 713177, mRNA se   7.19       440116   AI798851   Hs.283108   hemoglobin, gamma G   7.12       450230   AW016607   Hs.201582   ESTs   7.08       456332   AA228357       gb: nc39d05.r1 NCI_CGAP_Pr2  Homo sapiens     7.04       421814   L12350   Hs.108623   thrombospondin 2   6.89       440774   AI420611   Hs.127832   ESTs   6.86       428065   AI634046   Hs.157313   ESTs   6.78       422330   D30783   Hs.115263   epiregulin   6.72       413950   AA249096   Hs.32793   ESTs   6.67       438011   BE466173   Hs.145696   splicing factor (CC1.3)   6.62       421057   T58283   Hs.10450     Homo sapiens  cDNA: FLJ22063 fis, clone H   6.58       428698   AA852773   Hs.334838   KIAA1866 protein   6.40       408806   AW847814   Hs.289005     Homo sapiens  cDNA: FLJ21532 fis, clone C   6.38       425787   AA363867   Hs.155029   ESTs   6.38       435812   AA700439   Hs.188490   ESTs   6.32       448974   AL049390   Hs.22689     Homo sapiens  mRNA; cDNA DKFZp586O1318 (f   6.28       418875   W19971   Hs.233459   ESTs   6.22       407284   AI539227   Hs.214039   hypothetical protein FLJ23556   6.17       408243   Y00787   Hs.624   interleukin 8   6.12       434936   AI285970   Hs.183817   ESTs   6.12       412088   AI689496   Hs.108932   ESTs   6.04       450377   AB033091   Hs.74313   KIAA1265 protein   6.00       407618   AW054922   Hs.53478     Homo sapiens  cDNA FLJ12366 fis, clone MA   5.98       408296   AL117452   Hs.44155   DKFZP586G1517 protein   5.94       456999   AA319798   Hs.298581   eukaryotic translation elongation factor   5.90       432559   AW452948   Hs.257631   ESTs   5.88       423349   AF010258   Hs.127428   homeo box A9   5.84       436100   AA704806   Hs.143842   ESTs, Weakly similar to 2004399A chromos   5.84       453204   R10799   Hs.191990   ESTs   5.84       429183   AB014604   Hs.197955   KIAA0704 protein   5.78       427882   AA640987   Hs.193767   ESTs   5.72       447033   AI357412   Hs.157601   ESTs   5.70       428054   AI948688   Hs.266619   ESTs   5.66       414504   AW069181   Hs.115175   sterile-alpha motif and leucine zipper c   5.64       442806   AW294522   Hs.149991   ESTs   5.64       418259   AA215404   Hs.137289   ESTs   5.60       434963   AW974957   Hs.288719     Homo sapiens  cDNA FLJ12142 fis, clone MA   5.60       419999   AI760942   Hs.191754   ESTs   5.58       431749   AL049263   Hs.306292     Homo sapiens  mRNA; cDNA DKFZp564F133 (fr   5.58       422790   AA809875   Hs.25933   ESTs   5.56       440980   AL042005   Hs.1117   tripeptidyl peptidase II   5.48       432451   AW972771   Hs.292471   ESTs, Weakly similar to ALU1_HUMAN ALU S   5.46       438578   AA811244   Hs.164168   ESTs   5.44       410467   AF102546   Hs.63931   dachshund (Drosophila) homolog   5.42       426317   AA312350   Hs.169294   transcription factor 7 (T-cell specific,   5.42       450164   AI239923   Hs.30098   ESTs   5.40       438899   AF085833   Hs.135624   ESTs   5.38       432945   AL043683   Hs.8173   hypothetical protein FLJ10803   5.36       437176   AW176909   Hs.42346   calcineurin-binding protein calsarcin-1   5.34       419829   AI924228   Hs.115185   ESTs, Moderately similar to PC4259 ferri   5.33       407966   AA295052   Hs.38516     Homo sapiens , clone MGC:15887, mRNA, com   5.30       447342   AI199268   Hs.19322     Homo sapiens , Similar to RIKEN cDNA 2010   5.26       419682   H13139   Hs.92282   paired-like homeodomain transcription fa   5.26       421097   AI280112   Hs.125232     Homo sapiens  cDNA FLJ13266 fis, clone OV   5.22       443373   AI792868   Hs.135365   ESTs   5.22       412059   AA317962   Hs.249721   ESTs, Moderately similar to PC4259 ferri   5.21       443651   W22152   Hs.282929   ESTs   5.21       411274   NM_002776   Hs.69423   kallikrein 10   5.17       421999   U50535   Hs.110630   Human BRCA2 region, mRNA sequence CG006   5.17       426981   AL044675   Hs.173081   KIAA0530 protein   5.14       431319   AA873350   Hs.302232   ESTs   5.10       434966   AA657494       gb: nt66f04.s1 NCI_CGAP_Pr3  Homo sapiens     5.10       418830   BE513731   Hs.88959   hypothetical protein MGC4816   5.08       428290   AI932995   Hs.183475     Homo sapiens  clone 25061 mRNA sequence   5.07       408784   AW971350   Hs.63386   ESTs   5.04       411975   AI916058   Hs.144583   ESTs   5.02       409760   AA302840       gb: EST10534 Adipose tissue, white I Homo   4.97       420717   AA284447   Hs.271887   ESTs   4.96       417035   AA192455   Hs.22968     Homo sapiens  clone IMAGE: 451939, mRNA se   4.95       434442   AA737415   Hs.152826   ESTs   4.94       441328   AI982794   Hs.159473   ESTs   4.92       438962   BE046594       gb: hn41c11.x1 NCI_CGAP_RDF2  Homo sapiens     4.92       451277   AK001123   Hs.26176   hypothetical protein FLJ10261   4.92       438406   BE273296   Hs.254467     Homo sapiens  cDNA FLJ13255 fis, clone OV   4.90       424950   AA602917   Hs.156974   ESTs   4.88       436823   AW749865   Hs.293645   ESTs, Weakly similar to I38022 hypotheti   4.87       444783   AK001468   Hs.62180   anillin (Drosophila Scraps homolog), act   4.82       444301   AK000136   Hs.10760   asporin (LRR dass 1)   4.80       445390   AI222165   Hs.144923   ESTs   4.80       439608   AW864696   Hs.301732   hypothetical protein MGC5306   4.78       450506   NM_004460   Hs.418   fibroblast activation protein, alpha   4.78       432682   AI376400   Hs.159588   ESTs   4.76       426086   T94907   Hs.188572   ESTs   4.76       435981   H74319   Hs.188620   ESTs   4.74       432340   AA534222       gb: nj21d02.s1 NCI_CGAP_AA1  Homo sapiens     4.72       435756   AI418466   Hs.33665   ESTs   4.72       447982   H22953   Hs.137551   ESTs   4.72       449509   AA001615   Hs.84561   ESTs   4.72       407946   AA226495   Hs.154292   ESTs   4.70       426215   AW963419   Hs.155223   stanniocalcin 2   4.70       414783   AW069569   Hs.278270   unactive progesterone receptor, 23 kD   4.68       417601   NM_014735   Hs.82292   KIAA0215 gene product   4.68       438401   AW075485   Hs.286049   phosphoserine aminotransferase   4.68       449032   AA045573   Hs.22900   nuclear factor (erythroid-derived 2)-lik   4.68       426501   AW043782   Hs.293616   ESTs   4.67       409024   AW883529   Hs.173830   ESTs, Weakly similar to ALU7_HUMAN ALU S   4.67       439848   AW979249       gb: EST391359 MAGE resequences, MAGP Homo   4.66       424762   AL119442   Hs.183684   eukaryotic translation initiation factor   4.66       442007   AA301116   Hs.142838   nucleolar phosphoprotein Nopp34   4.62       409632   W74001   Hs.55279   serine (or cysteine) proteinase inhibito   4.62       432409   AA806538   Hs.130732   KIAA1575 protein   4.60       452220   BE158006   Hs.212296   ESTs   4.60       442577   AA292998   Hs.163900   ESTs   4.58       434001   AW950905   Hs.3697   serine (or cysteine) proteinase inhibito   4.58       414271   AK000275   Hs.75871   protein kinase C binding protein 1   4.58       433854   AA610649   Hs.333239   ESTs   4.56       431315   AW972227   Hs.163986     Homo sapiens  cDNA: FLJ22765 fis, clone K   4.53       434220   AI174777   Hs.283039     Homo sapiens  PRO2492 mRNA, complete cds   4.50       457752   AI821270   Hs.285643     Homo sapiens  cDNA FLJ14364 fis, clone HE   4.50       449941   AW450536   Hs.209260   ESTs   4.48       415116   AA160363   Hs.269956   ESTs   4.47       414386   X00442   Hs.75990   haptoglobin   4.47       422956   BE545072   Hs.122579   hypothetical protein FLJ10461   4.44       423974   AL118754       gb: DKFZp761P1910_r1 761 (synonym: hamy2)   4.44       449618   AI076459   Hs.15978   KIAA1272 protein   4.44       428279   AA425310   Hs.155768   ESTs, Weakly similar to A47582 B-4 cell gr   4.42       430573   AA744550   Hs.136345   ESTs   4.42       430929   AA489166   Hs.156933   ESTs   4.40       433530   BE349534   Hs.281789   ESTs   4.40       446099   T93096   Hs.17126   hypothetical protein MGC15912   4.40       447082   T85314   Hs.42644   thioredoxin-like   4.39       407168   R45175   Hs.117183   ESTs   4.38       417067   AJ001417   Hs.81086   solute carrier family 22 (extraneuronal   4.38       408380   AF123050   Hs.44532   diubiquitin   4.36       431379   AA504264   Hs.182937   peptidylprolyl isomerase A (cyclophilin   4.36       406671   AA129547   Hs.285754   met proto-oncogene (hepatocyte growth fa   4.34       419317   AA236282   Hs.172318   ESTs   4.32       450295   AI766732   Hs.210628   ESTs   4.32       423578   AW960454   Hs.222830   ESTs   4.31       419553   N34145   Hs.250614   ESTs, Moderately similar to ZN91_HUMAN Z   4.31       429512   AA453987   Hs.144802   ESTs   4.30       426848   H72531   Hs.36190   ESTs   4.30       429831   AA564489   Hs.137526   ESTs   4.30       433735   AA608955   Hs.109653   ESTs   4.30       450546   AA010200   Hs.175551   ESTs   4.27       421059   AI654133   Hs.30212   thyroid receptor interacting protein 15   4.27       413243   AA769266   Hs.193657   ESTs   4.26       433230   AW136134   Hs.220277   ESTs   4.22       439717   W94472   Hs.59529   ESTs, Moderately similar to ALU1_HUMAN A   4.20       439382   AI954880   Hs.134604   ESTs   4.19       450157   AW961576   Hs.60178   ESTs   4.17       451690   AW451469   Hs.209990   ESTs   4.17       418661   NM_001949   Hs.1189   E2F transcription factor 3   4.16       443135   AI376331   Hs.156103   ESTs   4.16       443148   AI034357   Hs.211194   ESTs, Weakly similar to ALU8_HUMAN ALU S   4.16       407765   AW076027   Hs.257711   ESTs, Moderately similar to ALU8_HUMAN A   4.14       428825   AI084336   Hs.128783   ESTs, Weakly similar to I38022 hypotheti   4.14       447519   U46258   Hs.339665   ESTs   4.14       439451   AF086270   Hs.278554   heterochromatin-like protein 1   4.12       450219   AI826999   Hs.224624   ESTs   4.12       431451   AA761378   Hs.192013   ESTs   4.11       432917   NM_014125   Hs.279812   PRO0327 protein   4.10       431328   AA502999   Hs.291591   ESTs   4.09       425992   AA367069   Hs.100636   ESTs   4.08       404571               4.06       420911   U77413   Hs.100293   O-linked N-acetylglucosamine (GlcNAc) tr   4.06       421114   AW975051   Hs.293156   ESTs, Weakly similar to I78885 serine/th   4.06       432731   R31178   Hs.287820   fibronectin 1   4.06       433588   AI056872   Hs.133386   ESTs   4.06       434658   AI624436   Hs.310286   ESTs   4.06       444040   AF204231   Hs.182982   golgin-67   4.06       444984   H15474   Hs.132898   fatty acid desaturase 1   4.06       438543   AA810141   Hs.192182   ESTs   4.05       413497   BE177661       gb: RC1-HT0598-020300-011-h02 HT0598 Homo   4.04       434575   AI133446   Hs.299964     Homo sapiens  clone FLB7723 PRO2055 mRNA,   4.04       430256   AA470152   Hs.192195   ESTs   4.04       424839   AA740632   Hs.120850   ESTs, Weakly similar to ALU1_HUMAN ALU S   4.02       429048   AI372949   Hs.44241     Homo sapiens  cDNA: FLJ21447 fis, clone C   4.02       449429   AA054224   Hs.59847   ESTs   4.02       410762   AF226053   Hs.66170   HSKM-B protein   4.00       418876   AA740616       gb: nyg7f11.s1 NCI_CGAP_GCB1  Homo sapiens     4.00       425905   AB032959   Hs.318584   novel C3HC4 type Zinc finger (ring finge   4.00       429500   X78565   Hs.289114   hexabrachion (tenascin C, cytotactin)   4.00       431393   AW971493   Hs.134269   ESTs, Highly similar to cytokine recepto   4.00       435008   AF150262   Hs.162898   ESTs   4.00       431361   AW971375   Hs.292921   ESTs   3.97       444816   Z48633   Hs.283742     H. sapiens , mRNA for retrotransposon   3.96       434701   AA460479   Hs.321707   KIAA0742 protein   3.96       413886   AW958264   Hs.103832   similar to yeast Upf3, variant B   3.95       424905   NM_002497   Hs.153704   NIMA (never in mitosis gene a)-related k   3.92       428479   Y00272   Hs.184572   cell division cycle 2, G1 to S and G2 to   3.91       435714   AA699325   Hs.269880   ESTs   3.86       447514   AI809314   Hs.208501   ESTs, Weakly similar to B34087 hypotheti   3.86       453818   BE256832   Hs.10711   hypothetical protein FLJ13449   3.85       433586   T85301       gb: yd78d06.s1 Soares fetal liver spleen   3.85       440638   AI376551       gb: te64e10.x1 Soares_NFL_T_GBC_S1 Homo s   3.85       417819   AI253112   Hs.133540   ESTs   3.84       409596   BE244200   Hs.55075   KIAA0410 gene product   3.83       423129   L44396   Hs.124106     Homo sapiens  cDNA FLJ11941 fis, clone HE   3.83       453884   AA355925   Hs.36232   KIAA0186 gene product   3.83       431193   AW749505   Hs.296770   KIAA1719 protein   3.81       409262   AK000631   Hs.52256   hypothetical protein FLJ20624   3.80       425568   AW963118   Hs.161784   ESTs   3.78       441085   AW136551   Hs.181245     Homo sapiens  cDNA FLJ12532 fis, clone NT   3.77       428079   AA421020   Hs.208919   ESTs   3.77       412490   AW803564   Hs.288850     Homo sapiens  cDNA: FLJ22528 fis, clone H   3.76       435354   AA678267   Hs.117115   ESTs   3.75       436535   AW295687   Hs.254420   ESTs   3.74       420439   AW270041   Hs.193053   eukaryotic translation initiation factor   3.72       436090   AI640635   Hs.116468   EST   3.71       416265   AA177088   Hs.190065   ESTs   3.70       417715   AW969587   Hs.86366   ESTs   3.67       435677   AA694142   Hs.293726   ESTs, Weakly similar to TSGA RAT TESTIS   3.67       438607   AW080237   Hs.252884   ESTs   3.66       408194   AA601038   Hs.191797   ESTs, Weakly similar to S65657 alpha-1C-   3.65       417211   T97617   Hs.269092   ESTs   3.60       435538   AB011540   Hs.4930   low density lipoprotein receptor-related   3.59       410390   AA876905   Hs.125286   ESTs   3.58       438818   AW979008   Hs.222487   ESTs   3.57       431416   AA532718   Hs.178604   ESTs   3.57       433517   AW022133   Hs.189838   ESTs   3.56       428355   BE256452   Hs.2257   vitronectin (serum spreading factor, som   3.56       432954   AI076345   Hs.214199   ESTs   3.53       434466   AB037829   Hs.3862   regulator of nonsense transcripts 2; DKF   3.53       421933   R98881   Hs.109655   sex comb on midleg (Drosophila)-like 1   3.52       422082   AA016188   Hs.111244   hypothetical protein   3.52       437135   AL038624   Hs.208752   ESTs, Weakly similar to ALU8_HUMAN ALU S   3.49       424723   BE409813   Hs.152337   protein arginine N-methyltransferase 3(h   3.49       434280   BE005398       gb: CM1-BN0116-150400-189-h02 BN0116 Homo   3.49       407289   AA135159   Hs.203349     Homo sapiens  cDNA FLJ12149 fis, clone MA   3.48       417670   R07785       gb: yf15c06.r1 Soares fetal liver spleen   3.48       431615   AW295859   Hs.235860   ESTs   3.48       429355   AW973253   Hs.292689   ESTs   3.45       430068   AA464964       gb: zx80f10.s1 Soares ovary tumor NbHOT H   3.45       432929   AW207166   Hs.191265   ESTs   3.44       437763   AA469369   Hs.5831   tissue inhibitor of metalloproteinase 1   3.44       445674   BE410347   Hs.13063   transcription factor CA150   3.42       408113   T82427   Hs.194101     Homo sapiens  cDNA: FLJ20869 fis, clone A   3.42       408908   BE296227   Hs.250822   serine/threonine kinase 15   3.41       432235   AA531129   Hs.190297   ESTs   3.41       453985   N44545   Hs.251865   ESTs   3.41       415736   AA827082   Hs.291872   ESTs   3.38       430220   BE378277   Hs.152230   ESTs   3.37       426510   AW861225   Hs.194637   BANP homolog, SMAR1 homolog   3.37       412104   AW205197   Hs.240951     Homo sapiens , Similar to RIKEN cDNA 2210   3.36       411573   AB029000   Hs.70823   KIAA1077 protein   3.33       413816   AW958181   Hs.189998   ESTs   3.32       428057   AI343641   Hs.185798   ESTs   3.32       436280   AI690734   Hs.131740     Homo sapiens  cDNA: FLJ22562 fis, clone H   3.31       449365   AW968261   Hs.118913   ESTs, Moderately similar to T46371 hypot   3.31       440659   AF134160   Hs.7327   claudin 1   3.30       436110   AA704899   Hs.291651   ESTs, Weakly similar to I38022 hypotheti   3.29       433862   D86960   Hs.3610   KIAA0205 gene product   3.29       424624   AB032947   Hs.151301   Ca2+ dependent activator protein for secr   3.29       439955   AW203959   Hs.149532   ESTs   3.28       417333   AL157545   Hs.42179   bromodomain and PHD finger containing, 3   3.28       436150   AW510927   Hs.125243   ESTs   3.27       414900   AW452420   Hs.248678   ESTs   3.26       439349   AI660898   Hs.195602   ESTs   3.25       428255   AI627478   Hs.187670   ESTs   3.24       436217   T53925   Hs.107   fibrinogen-like 1   3.24       429083   Y09397   Hs.227817   BCL2-related protein A1   3.24       422244   Y08890   Hs.113503   karyopherin (importin) beta 3   3.22       430178   AW449612   Hs.152475   ESTs   3.21       413810   AW197644   Hs.19107   ESTs   3.20       428728   NM_016625   Hs.191381   hypothetical protein   3.20       437151   AA745618   Hs.194637   BANP homolog, SMAR1 homolog   3.19       427051   BE178110   Hs.173374     Homo sapiens  cDNA FLJ10500 fis, clone NT   3.19       438378   AW970529   Hs.86434   hypothetical protein FLJ21816   3.19       439943   AW083789   Hs.124620   ESTs   3.18       439280   AI125436   Hs.48752   ESTs   3.18       452336   AA960961   Hs.305953   zinc finger protein 83 (HPF1)   3.17       433713   AW976511   Hs.112592   ESTs   3.16       414998   NM_002543   Hs.77729   oxidised low density lipoprotein (lectin   3.14       407328   AA508857   Hs.187748   ESTs, Weakly similar to ALU1_HUMAN ALU S   3.14       432722   AA830532   Hs.326150   ESTs   3.14       419457   AA243146   Hs.209334   ESTs, Moderately similar to S23A_HUMAN P   3.11       449987   AW079749   Hs.184719   ESTs, Weakly similar to ALU1_HUMAN ALU S   3.11       418522   AA605038   Hs.7149     Homo sapiens  cDNA: FLJ21950 fis, clone H   3.09       409969   AW514668   Hs.194258   ESTs, Moderately similar to ALU5_HUMAN A   3.08       436299   AK000767   Hs.5111   hypothetical protein FLJ20729   3.08       406687   M31126   Hs.272620   pregnancy specific beta-1-glycoprotein 9   3.07       408242   AA251594   Hs.43913   PIBF1 gene product   3.07       444614   R44284   Hs.2730   heterogeneous nuclear ribonucleoprotein   3.06       459407   N92114       gb: za22h11.r1 Soares fetal liver spleen   3.05       433972   AI878910   Hs.3688   cisplatin resistance-associated overexpr   3.04       427704   AW971063   Hs.292882   ESTs   3.03       440255   AI932285   Hs.160569   ESTs   3.03       424542   AI860558   Hs.272009   ESTs, Weakly similar to ALU2_HUMAN ALU S   3.03       413822   R08950   Hs.272044   ESTs, Weakly similar to ALU1_HUMAN ALU S   3.02       433944   AL117518   Hs.3686   KIAA0978 protein   3.01       440428   BE560954       gb: 601347719F1 NIH_MGC_8  Homo sapiens  cD   3.00                       #“average” normal colon tissues was greater than or equal to 3.0. The “average” colon cancer derived liver metastases level was set to the 50th percentile. The “average” normal colon tissue level was set to the 50th percentile.                                                     
     [0350]                       TABLE 21A                       Pkey   CAT Number   Accession                  409760   115373_1   AA302840 T93016 T92950 AA077551       413497   1373771_1   BE177661 H06215 BE144709 BE144829       417670   1692163_1   R07785 T85948 T86972       418876   179960_1   AA740616 AA654854 AA229923       419145   182217_1   N99638 AW973750 AA328271 H90994               AA558020 AA234435 N59599 R94815       423974   233842_1   AL118754 AA333202 H38001       430068   312849_1   AA464964 M85405 AA947566       432340   345248_1   AA534222 AA632632 T81234       433586   370470_1   T85301 AW517087 AA601054 BE073959       434280   382816_1   BE005398 AA628622 AA994155       434966   396504_1   AA657494 AI582663 AI581639       438962   467390_1   BE046594 BE046667 AA828585 AI207343       439848   477806_1   AW979249 D63277 AA846968       440428   49370_−1   BE560954       440638   499025_1   AI376551 T87714 AA897445       456332   179104_1   AA228357 AW841786 AW841716                       # and Alignment Tools (DoubleTwist, Oakland California). The Genbank accession numbers for sequences comprising each cluster are listed in the “Accession” column.                                     
     [0351]                                   TABLE 21B                                   Pkey   Ref   Strand   Nt_position                          404571   7249169   Minus   112450-112648                                                                        
     [0352]               TABLE 22                          177 GENES DOWN-REGULATED IN COLON CANCER DERIVED       LIVER METASTASES COMPARED TO NORMAL COLON TISSUE                                 Pkey   ExAccn   UnigeneID   Unigene Title   R1                                         425196   AL037915   Hs.155097   carbonic anhydrase II   0.03       414522   AW518944   Hs.76325   step II splicing factor SLU7   0.03       409153   W03754   Hs.50813   hypothetical protein FLJ20022   0.03       452594   AU076405   Hs.29981   solute carrier family 26 (sulfate transp   0.03       424326   NM_014479   Hs.145296   disintegrin protease   0.04       414798   AI286323   Hs.97411   hypothetical protein MGC12335   0.04       432150   AK000224   Hs.272789   hypothetical protein FLJ20217   0.04       425206   NM_002153   Hs.155109   hydroxysteroid (17-beta) dehydrogenase 2   0.05       437145   AF007216   Hs.5462   solute carrier family 4, sodium bicarbon   0.05       447513   AW955776   Hs.313500   ESTs, Moderately similar to ALU7_HUMAN A   0.05       414807   AI738616   Hs.77348   hydroxyprostaglandin dehydrogenase 15-(N   0.06       428934   AF039401   Hs.194659   chloride channel, calcium activated, fam   0.06       432251   AW972983   Hs.232165   polycythemia rubra vera 1; cell surface   0.07       431727   AW293464   Hs.162031   ESTs   0.07       421515   Y11339   Hs.105352   GalNAc alpha-2, 6-sialyltransferase I, I   0.07       414555   N98569   Hs.76422   phospholipase A2, group IIA (platelets,   0.08       412047   AA934589   Hs.49696   ESTs   0.08       412056   T28160   Hs.778   guanylate cyclase activator 1B (retina)   0.08       422440   NM_004812   Hs.116724   aldo-keto reductase family 1, member B10   0.08       450684   AA872605   Hs.25333   interleukin 1 receptor, type II   0.09       418935   T28499   Hs.89485   carbonic anhydrase IV   0.09       433658   L03678   Hs.156110   immunoglobulin kappa constant   0.09       422260   AA315993   Hs.105484   regenerating gene type IV   0.09       433336   AF017986   Hs.31386   secreted frizzled-related protein 2   0.09       426784   U03749   Hs.172216   chromogranin A (parathyroid secretory pr   0.09       441888   AI733306   Hs.128071   hypothetical protein FLJ21302   0.10       440624   AF017987   Hs.7306   secreted frizzled-related protein 1   0.10       420929   AI694143   Hs.296251   programmed cell death 4   0.10       429970   AK000072   Hs.227059   chloride channel, calcium activated, fam   0.10       417233   W25005   Hs.24395   small inducible cytokine subfamily B (Cy   0.10       414802   AI793107   Hs.27018   Ris   0.10       424566   M16801   Hs.1790   nuclear receptor subfamily 3, group C, m   0.11       421996   AW583807   Hs.1460   glucagon   0.11       423371   AU076819   Hs.1650   solute carrier family 26, member 3   0.11       406741   AA058357   Hs.74466   carcinoembryonic antigen-related cell ad   0.11       414176   BE140638   Hs.75794   endothelial differentiation, lysophospha   0.11       408741   M73720   Hs.646   carboxypeptidase A3 (mast cell)   0.11       424527   AW138558   Hs.267158   ESTs, Weakly similar to I54374 gene NF2   0.12       426682   AV660038   Hs.2056   UDP glycosyltransferase 1 family, polype   0.12       453967   AW009077   Hs.232947   ESTs   0.12       425920   AL049977   Hs.162209   claudin 8   0.13       408134   AK000184   Hs.42945   acid sphingomyelinase-like phosphodieste   0.13       457407   AA505035   Hs.195651   ESTs   0.13       446500   U78093   Hs.15154   sushi-repeat-containing protein, X chrom   0.14       422487   AJ010901   Hs.198267   mucin 4, tracheobronchial   0.14       409196   NM_001874   Hs.334873   carboxypeptidase M   0.14       416426   AA180256   Hs.210473     Homo sapiens  cDNA FLJ14872 fis, clone PL   0.14       406636   L12064       gb:  Homo sapiens  (clone WR4.12VL) anti-th   0.14       457982   AW856093   Hs.183617   ESTs   0.14       407744   AB020629   Hs.38095   ATP-binding cassette, sub-family A (ABC1   0.14       430378   Z29572   Hs.2556   tumor necrosis factor receptor superfami   0.14       424885   AI333771   Hs.82204   ESTs   0.14       423555   AW958201   Hs.178589   hepatocellular carcinoma antigen gene 52   0.14       444237   AA336878   Hs.9842   Human DNA sequence from clone RP4-788L20   0.14       445848   AA774824   Hs.13377     Homo sapiens  clone 23649 and 23755 unkno   0.14       451062   AL110125   Hs.25910     Homo sapiens  mRNA; cDNA DKFZp564C1416 (f   0.14       436485   X59135   Hs.156110   immunoglobulin kappa constant   0.14       423655   AA722425   Hs.182785   ESTs, Moderately similar to 1207289A rev   0.15       417332   AW972717   Hs.288462   hypothetical protein FLJ21511   0.15       427506   AK000134   Hs.179100   hypothetical protein FLJ20127   0.15       430712   AW044647   Hs.196284   ESTs   0.15       421666   AL035250   Hs.1408   endothelin 3   0.16       425692   D90041   Hs.155956   N-acetyltransferase 1 (arylamine N-acety   0.16       429412   NM_006235   Hs.2407   POU domain, class 2, associating factor   0.16       433745   AF075320   Hs.28980   hypothetical protein FLJ14540   0.16       450085   AW293791   Hs.60162     Homo sapiens  cDNA: FLJ21528 fis, clone C   0.16       417820   D87449   Hs.82635   UDP-glucuronic acid/UDP-N-acetylgalactos   0.16       406722   H27498   Hs.293441     Homo sapiens  SNC73 protein (SNC73) mRNA,   0.16       426488   X03350   Hs.4   alcohol dehydrogenase 1B (class I), beta   0.16       436327   AA813075   Hs.120181   ESTs   0.16       408873   AL0A6017   Hs.182278   calmodulin 2 (phosphorylase kinase, delt   0.16       429524   AB033037   Hs.205293   KIAA1211 protein   0.16       447023   AA356764   Hs.17109   integral membrane protein 2A   0.17       424264   D80400   Hs.239388   Human DNA sequence from clone RP1-304B14   0.17       410310   J02931   Hs.62192   coagulation factor III (thromboplastin,   0.17       432563   NM_013261   Hs.198468   peroxisome proliferative activated recep   0.17       406897   M57417       gb:  Homo sapiens  mucin (mucin) mRNA, part   0.17       451096   BE383234   Hs.25925     Homo sapiens , clone MGC: 15393, mRNA, com   0.17       447726   AL137638   Hs.19366   matrilin 2   0.17       409549   AB029015   Hs.54886   phospholipase C, epsilon 2   0.17       433334   AI927208   Hs.231958   matrix metalloproteinase 28   0.17       425849   AJ000512   Hs.296323   serum/glucocorticoid regulated kinase   0.17       407360   X13075       gb: Human 2a12 mRNA for kappa-immunoglobu   0.17       430627   U61148   Hs.247685   atonal homolog 1 (Drosophila)   0.17       418807   NM_004944   Hs.88646   deoxyribonuclease I-like 3   0.18       453399   Z70295   Hs.32966   guanylate cyclase activator 2B (uroguany   0.18       422994   AW891802   Hs.296276   ESTs   0.18       432134   AI816782   Hs.122583   hypothetical protein FLJ21934   0.18       400417   X72475           0.18       443506   H10661   Hs.192124   ESTs, Weakly similar to I38022 hypotheti   0.18       428470   AC002301   Hs.184507     Homo sapiens  Chromosome 16 BAC clone CIT   0.18       451928   AI823801   Hs.30315   CTCL tumor antigen se57-1   0.18       429576   BE242628   Hs.209061   sudD (suppressor of bimD6, Aspergillus n   0.18       422106   D84239   Hs.111732   Fc fragment of IgG binding protein   0.19       430304   AL122071   Hs.238927     Homo sapiens  mRNA; CDNA DKFZp434H1235 (f   0.19       452852   AK001972   Hs.30822   hypothetical protein FLJ11110   0.19       421904   BE143533   Hs.109309   hypothetical protein FLJ20035   0.19       417165   R80137   Hs.302738     Homo sapiens  cDNA: FLJ21425 fis, clone C   0.19       417771   AA804698   Hs.82547   retinoic acid receptor responder (tazaro   0.19       452802   AU076403   Hs.323468   electron-transferring-flavoprotein dehyd   0.19       450680   AF131784   Hs.25318     Homo sapiens  clone 25194 mRNA sequence   0.19       420061   AW024937   Hs.29410   ESTs   0.19       426828   NM_000020   Hs.172670   activin A receptor type II-like 1   0.19       408190   AB032963   Hs.43577   ATPase, Class I, type 8B, member 2   0.19       437682   AA476652   Hs.94952     Homo sapiens  cDNA: FLJ23371 fis, clone H   0.19       449110   H56112       gb: yq95f07.r1 Soares fetal liver spleen   0.19       446727   AB011095   Hs.16032   KIAA0523 protein   0.19       408395   BE072425   Hs.44579   hypothetical protein FLJ20199   0.20       423541   AA296922   Hs.129778   gastrointestinal peptide   0.20       410850   AW362867   Hs.302738     Homo sapiens  cDNA: FLJ21425 fis, clone C   0.20       412420   AL035668   Hs.73853   bone morphogenetic protein 2   0.20       423942   AF209704   Hs.135723   glycolipid transfer protein   0.20       421832   NM_016098   Hs.108725   HSPC040 protein   0.20       459046   AA910339   Hs.26216   LOC50627   0.20       421360   AA297012   Hs.103839   erythrocyte membrane protein band 4.1-li   0.20       438091   AW373062   Hs.83623   nuclear receptor subfamily 1, group I, m   0.20       403047               0.20       421712   AK000140   Hs.107139   hypothetical protein   0.20       427333   AF067797   Hs.176658   aquaporin 8   0.20       421964   X73079   Hs.288579   polymeric immunoglobulin receptor   0.20       438089   W05391   Hs.83623   nuclear receptor subfamily 1, group I, m   0.21       445200   AA084460   Hs.12409   somatostatin   0.21       404854               0.21       426390   AA377299   Hs.90431   ESTs   0.21       403381               0.21       449833   R82252   Hs.106106   protein kinase (cAMP-dependent, catalyti   0.21       457718   F18572   Hs.22978   ESTs, Weakly similar to ALU4_HUMAN ALU S   0.21       435730   AB020635   Hs.4984   KIAA0828 protein   0.21       431518   AA743462   Hs.165337   ESTs   0.21       412589   R28660   Hs.24305   ESTs   0.21       432584   AA928829   Hs.47099   hypothetical protein FLJ21212   0.21       426088   AF038007   Hs.166196   ATPase, Class I, type 8B, member 1   0.21       429143   AA333327   Hs.197335   plasma glutamate carboxypeptidase   0.21       414429   R51494   Hs.71818   ESTs   0.22       439670   AF088076   Hs.59507   ESTs, Weakly similar to AC004858 3 U1 sm   0.22       406697   M21388   Hs.123017   Human unproductively rearranged Ig mu-ch   0.22       406663   U24683   Hs.302063   immunoglobulin heavy constant mu   0.22       407811   AW190902   Hs.40098   cysteine knot superfamily 1, BMP antagon   0.22       417880   BE241595   Hs.82848   selectin L (lymphocyte adhesion molecule   0.22       430107   AA465293   Hs.105069   ESTs   0.22       424273   W40460   Hs.144442   phospholipase A2, group X   0.22       419559   Y07828   Hs.91096   ring finger protein   0.22       413517   N76712   Hs.44829   ESTs, Weakly similar to I38022 hypotheti   0.22       407243   AA058357   Hs.74466   carcinoembryonic antigen-related cell ad   0.22       433906   AI167816   Hs.43355   ESTs   0.22       446203   Z47553   Hs.14286   flavin containing monooxygenase 5   0.22       403740               0.22       405701               0.22       413554   AA319146   Hs.75426   secretogranin II (chromogranin C)   0.22       419577   L36531   Hs.91296   integrin, alpha 8   0.23       451820   AW058357   Hs.337353   ESTs   0.23       424897   D63216   Hs.153684   frizzled-related protein   0.23       422880   AF228704   Hs.121524   glutathione reductase   0.23       430832   AI073913   Hs.100686   ESTs, Weakly similar to JE0350 Anterior   0.23       430753   AI432401   Hs.2659   fibrinogen-like 2   0.23       409060   AI815867   Hs.50130   necdin (mouse) homolog   0.23       412228   AW503785   Hs.73792   complement component (3d/Epstein Barr vi   0.24       414171   AA360328   Hs.865   RAP1A, member of RAS oncogene family   0.24       417916   NM_006416   Hs.82921   solute carrier family 35 (CMP.sialic aci   0.24       414589   AA149791   Hs.68864   ESTs, Weakly similar to phosphatidylseri   0.24       427167   AI239607   Hs.99196   hypothetical protein MGC11324   0.24       440630   BE561430   Hs.239388   Human DNA sequence from clone RP1-304B14   0.24       423044   AA320829   Hs.97266   protocadherin 18   0.24       441931   BE564830   Hs.23744   hypothetical protein FLJ12899   0.24       443060   D78874   Hs.8944   procollagen C-endopeptidase enhancer 2   0.24       405441               0.24       407241   M34516       gb: Human omega light chain protein 14.1   0.24       415165   AW887604   Hs.78065   complement component 7   0.24       426447   AV655843   Hs.169919   electron-transfer-flavoprotein, alpha po   0.24       410748   BE383816   Hs.12532   chromosome 1 open reading frame 21   0.24       436032   AA150797   Hs.109276   latexin protein   0.24       414256   AW410035   Hs.75862   MAD (mothers against decapentaplegic, Dr   0.24       414197   W44877   Hs.55501   ESTs   0.24       406836   AW514501   Hs.156110   immunoglobulin kappa constant   0.24       437083   AW082597   Hs.244862   ESTs   0.25       421709   AA159394   Hs.107056   CED-6 protein   0.25       426512   AW511656   Hs.170177   Meis1 (mouse) homolog   0.25                       #liver metastases to “average” normal colon tissues was less than or equal to 0.25. The “average” colon cancer derived liver metastases level was set to the 50th percentile. The “average” normal adult tissue level was set to the 50th percentile.                                                     
     [0353]               TABLE 22A                          Table 22A shows the accession numbers for those pkeys lacking       unigeneID&#39;s for Tables 21A. For each probeset we have       listed the gene cluster number from which the oligonucleotides       were designed. Gene clusters were compiled using sequences       derived from Genbank ESTs and mRNAs. These sequences were       clustered based on sequence similarity using Clustering and       Alignment Tools (DoubleTwist, Oakland California). The Genbank       accession numbers for sequences comprising each cluster are       listed in the “Accession” column.                             Pkey:   Unique Eos probeset identifier number           CAT number:   Gene cluster number           Accession:   Genbank accession numbers                         Pkey   CAT Number   Accession               449110   798430_1   H56112 H58047 AI630710 N58742                    
     [0354]                   TABLE 22B                          Pkey:   Unique number corresponding to an Eos probeset       Ref:   Sequence source. The 7 digit numbers in this column           are Genbank Identifier (GI) numbers. “Dunham I.           et al.” refers to the publication entitled           “The DNA sequence of human chromosome 22.”           Dunham I. et al., Nature (1999) 402:489-495.       Strand:   Indicates DNA strand from which exons were           predicted.       Nt_position:   Indicates nucleotide positions of predicted exons.                                     Pkey   Ref   Strand   Nt_position                       403047   3540153   Minus   59793-59968           403381   9438267   Minus   26009-26178           403740   7630882   Plus   86504-87227           404854   7143420   Plus   14260-14537           405441   7408124   Plus   100952-101283           405701   4263751   Plus   93243-93354                        
     [0355]               TABLE 23                          175 GENES UP-REGULATED IN COLON CANCER       DERIVED LIVER METASTASES COMPARED TO COLON CANCER       PRIMARY TUMOR SAMPLES CLASSIFIED AS DUKE&#39;S B SURVIVOR       Table 23 shows 175 genes up-regulated in colon cancer derived liver metastases compared to       colon cancer primary tumor samples classified as Duke&#39;s B stage with a positive survival       outcome (Duke&#39;s B survivor). These were selected from 59680 probesets on the       Affymetrix/Eos Hu03 GeneChip array such that the ratio of “average” colon cancer derived       liver metastases to “average” Duke&#39;s B survivor was greater than or equal to 3.0. The       “average” colon cancer derived liver metastases level was set to the 50th percentile. The       “average” Duke&#39;s B survivor level was set to the 50th percentile.                             Pkey:   Unique Eos probeset identifier number           ExAccn:   Exemplar Accession number, Genbank accession number           UnigeneID:   Unigene number           Unigene Title:   Unigene gene title           R1:   Genes up liver metastases vs Duke&#39;s B survivors                                 Pkey   ExAccn   UnigeneID   Unigene Title   R1               426101   AL049987   Hs.166361     Homo sapiens  mRNA; cDNA DKFZp564F112 (fr   9.06       432572   AI660840   Hs.191202   ESTs, Weakly similar to ALUE_HUMAN !!!!   7.96       424878   H57111   Hs.221132   ESTs   7.88       428046   AW812795   Hs.155381   ESTs, Moderately similar to I38022 hypot   7.48       407284   AI539227   Hs.214039   hypothetical protein FLJ23556   7.45       439943   AW083789   Hs.124620   ESTs   7.00       442369   AI565071   Hs.159983   ESTs   7.00       415116   AA160383   Hs.269956   ESTs   6.98       433517   AW022133   Hs.189838   ESTs   6.70       437176   AW176909   Hs.42346   calcineurin-binding protein calsarcin-1   6.68       440524   R71264   Hs.16798   ESTs   6.62       408806   AW847814   Hs.289005     Homo sapiens  cDNA: FLJ21532 fis, clone C   6.38       448974   AL049390   Hs.22689     Homo sapiens  mRNA; cDNA DKFZp586O1318 (f   6.28       412088   AI689496   Hs.108932   ESTs   6.04       417670   R07785       gb:yf15c06.r1 Soares fetal liver spleen   5.95       440774   AI420611   Hs.127832   ESTs   5.91       426086   T94907   Hs.188572   ESTs   5.90       436100   AA704806   Hs.143842   ESTs, Weakly similar to 2004399A chromos   5.84       453204   R10799   Hs.191990   ESTs   5.84       407289   AA135159   Hs.203349     Homo sapiens  cDNA FLJ12149 fis, clone MA   5.67       432435   BE218886   Hs.282070   ESTs   5.61       434963   AW974957   Hs.288719     Homo sapiens  cDNA FLJ12142 fis, clone MA   5.60       421221   AW276914   Hs.326714     Homo sapiens  clone IMAGE:713177, mRNA se   5.54       407328   AA508857   Hs.187748   ESTs, Weakly similar to ALU1_HUMAN ALU S   5.51       440980   AL042005   Hs.1117   tripeptidyl peptidase II   5.48       443651   W22152   Hs.282929   ESTs   5.42       412668   AA456195   Hs.10056   hypothetical protein FLJ14621   5.29       444838   AV651680   Hs.208558   ESTs   5.24       433312   AI241331   Hs.131765   ESTs, Moderately similar to I38937 DNA/R   5.11       430665   BE350122   Hs.157367   ESTs, Weakly similarto I78885 serine/th   5.11       434966   AA657494       gb:nt66f04.s1 NCI_CGAP_Pr3  Homo sapiens     5.10       426897   AW976570   Hs.97387   ESTs   5.08       432954   AI076345   Hs.214199   ESTs   5.07       431416   AA532718   Hs.178604   ESTs   5.00       420717   AA284447   Hs.271887   ESTs   4.96       424950   AA602917   Hs.156974   ESTs   4.94       438962   BE046594       gb:hn41c11.x1 NCI_CGAP_RDF2  Homo sapiens     4.92       419999   AI760942   Hs.191754   ESTs   4.89       435812   AA700439   Hs.188490   ESTs   4.86       418662   AI801098   Hs.151500   ESTs   4.79       428065   AI634046   Hs.157313   ESTs   4.77       407618   AW054922   Hs.53478     Homo sapiens  cDNA FLJ12366 fis, clone MA   4.75       435981   H74319   Hs.188620   ESTs   4.74       419145   N99638       gb:za39g11.r1 Soares fetal liver spleen   4.73       432340   AA534222       gb:nj21d02.s1 NCI_CGAP_AA1  Homo sapiens     4.72       447982   H22953   Hs.137551   ESTs   4.72       449509   AA001615   Hs.84561   ESTs   4.72       407946   AA226495   Hs.154292   ESTs   4.70       438607   AW080237   Hs.252884   ESTs   4.68       438406   BE273296   Hs.254467     Homo sapiens  cDNA FLJ13255 fis, clone OV   4.62       426818   AA554827   Hs.289115   DKFZp434A0131 protein   4.62       452220   BE158006   Hs.212296   ESTs   4.60       436823   AW749865   Hs.293645   ESTs, Weakly similar to I38022 hypotheti   4.60       433854   AA610649   Hs.333239   ESTs   4.56       413816   AW958181   Hs.189998   ESTs   4.52       428079   AA421020   Hs.208919   ESTs   4.52       421097   AI280112   Hs.125232     Homo sapiens  cDNA FLJ13266 fis, clone OV   4.50       417035   AA192455   Hs.22968   pi Homo sapiens clone IMAGE:451939, mRNA se   4.48       423974   AL118754       gb:DKFZp761P1910_r1 761 (synonym: hamy2)   4.44       449618   AI076459   Hs.15978   KIAA1272 protein   4.44       431615   AW295859   Hs.235860   ESTs   4.44       418876   AA740616       gb:ny97f11.s1 NCI_CGAP_GCB1  Homo sapiens     4.43       428279   AA425310   Hs.155766   ESTs, Weakly similar to A47582 B-cell gr   4.42       430573   AA744550   Hs.136345   ESTs   4.42       430929   AA489166   Hs.156933   ESTs   4.40       446099   T93096   Hs.17126   hypothetical protein MGC15912   4.40       439362   AI954880   Hs.134604   ESTs   4.36       421999   U50535   Hs.110630   Human BRCA2 region, mRNA sequence CG006   4.35       434220   AI174777   Hs.283039     Homo sapiens  PRO2492 mRNA, complete cds   4.33       432925   AA878324   Hs.192734   ESTs   4.32       417819   AI253112   Hs.133540   ESTs   4.30       426848   H72531   Hs.36190   ESTs   4.30       429831   AA564489   Hs.137526   ESTs   4.30       433735   AA608955   Hs.109653   ESTs   4.30       418884   AA230228   Hs.59197   ESTs   4.28       413243   AA769266   Hs.193657   ESTs   4.26       431749   AL049263   Hs.306292     Homo sapiens  mRNA; cDNA DKFZp564F133 (fr   4.23       428054   AI948688   Hs.266619   ESTs   4.22       413967   AW204431   Hs.117853   ESTs, Weakly similar to I38022 hypotheti   4.22       433230   AW136134   Hs.220277   ESTs   4.22       421057   T58283   Hs.10450     Homo sapiens  cDNA: FLJ22063 fis, clone H   4.22       423578   AW960454   Hs.222830   ESTs   4.21       439717   W94472   Hs.59529   ESTs, Moderately similar to ALU1_HUMAN A   4.20       443696   AW607444   Hs.134622   ESTs   4.20       432722   AA830532   Hs.326160   ESTs   4.18       435756   AI418466   Hs.33665   ESTs   4.14       428825   AI084336   Hs.128783   ESTs, Weakly similar to I38022 hypotheti   4.14       439451   AF086270   Hs.278554   heterochromatin-like protein 1   4.12       445943   AW898533   Hs.181574   ESTs   4.12       450219   AI826999   Hs.224624   ESTs   4.12       431379   AA504264   Hs.182937   peptidylprolyl isomerase A (cyclophilin   4.11       432451   AW972771   Hs.292471   ESTs, Weakly similar to ALU1_HUMAN ALU S   4.10       443148   AI034357   Hs.211194   ESTs, Weakly similar to ALU8_HUMAN ALU S   4.08       450177   AI698091   Hs.107845   ESTs   4.08       420911   U77413   Hs.100293   O-linked N-acetylglucosamine (GlcNAc) tr   4.06       421114   AW975051   Hs.293156   ESTs, Weakly similar to I78885 serine/th   4.06       432731   R31178   Hs.287820   fibronectin 1   4.06       433588   AI056872   Hs.133386   ESTs   4.06       434658   AI624436   Hs.310286   ESTs   4.06       444040   AF204231   Hs.182982   golgin-67   4.06       429512   AA453987   Hs.144802   ESTs   4.06       443349   AI052572   Hs.269864   ESTs, Weakly similar to ALU1_HUMAN ALU S   4.04       439867   AA847510   Hs.161292   ESTs   4.04       425955   T96509   Hs.248549   ESTs, Moderately similar to S65657 alpha   4.02       431393   AW971493   Hs.134269   ESTs, Highly similar to cytokine recepto   4.00       432125   AW972667   Hs.287510     Homo sapiens  cDNA FLJ12300 fis, clone MA   4.00       435468   AW362803   Hs.166271   ESTs   3.97       412059   AA317962   Hs.249721   ESTs, Moderately similar to PC4259 ferri   3.95       446682   AW205632   Hs.211198   ESTs   3.95       441328   AI982794   Hs.159473   ESTs   3.92       455778   BE088746       gb:CM2-BT0693-210300-123-d09 BT0693 Homo   3.90       438996   AW748336   Hs.168052   KIAA0421 protein   3.86       418303   AA215701   Hs.186541   ESTs, Weakly similar to I38022 hypotheti   3.85       444816   Z48633   Hs.283742     H.sapiens  mRNA for retrotransposon   3.84       429355   AW973253   Hs.292689   ESTs   3.83       438578   AA811244   Hs.164168   ESTs   3.83       432945   AL043683   Hs.8173   hypothetical protein FLJ10803   3.83       435318   T97301   Hs.18026   ESTs   3.82       449941   AW450536   Hs.209260   ESTs   3.80       424915   R42755   Hs.23096   ESTs   3.76       449987   AW079749   Hs.184719   ESTs, Weakly similar to ALU1_HUMAN ALU S   3.76       416265   AA177088   Hs.190065   ESTs   3.75       413497   BE177661       gb:RC1-HT0598-020300-011-h02 HT0598 Homo   3.74       412093   BE242691   Hs.14947   ESTs   3.74       413822   R08950   Hs.272044   ESTs, Weakly similar to ALU1_HUMAN ALU S   3.73       431915   AK000777   Hs.272197     Homo sapiens  cDNA FLJ20770 fis, clone CO   3.68       434442   AA737415   Hs.152826   ESTs   3.63       434959   AW974949   Hs.186564   ESTs, Weakly similar to I38022 hypotheti   3.63       427704   AW971063   Hs.292882   ESTs   3.62       426510   AW861225   Hs.194637   BANP homolog, SMAR1 homolog   3.60       435714   AA699325   Hs.269880   ESTs   3.60       432598   AI341227   Hs.157106   ESTs   3.57       438543   AA810141   Hs.192182   ESTs   3.55       422068   AI807519   Hs.104520     Homo sapiens  cDNA FLJ13694 fis, clone PL   3.54       418259   AA215404   Hs.137289   ESTs   3.54       428290   AI932995   Hs.183475     Homo sapiens  clone 25061 mRNA sequence   3.49       419457   AA243146   Hs.209334   ESTs, Moderately similar to S23A_HUMAN P   3.47       439312   AA833902   Hs.270745   ESTs   3.47       408784   AW971350   Hs.63388   ESTs   3.45       456332   AA228357       gb:nc39d05.r1 NCI_CGAP_Pr2  Homo sapiens     3.45       424762   AL119442   Hs.183684   eukaryotic translation initiation factor   3.44       442884   AI076570   Hs.134053   ESTs   3.44       421023   AW449855   Hs.96557     Homo sapiens  cDNA FLJ12727 fis, clone NT   3.43       434575   AI133446   Hs.299964     Homo sapiens  clone FLB7723 PRO2055 mRNA,   3.42       430433   AA478883   Hs.273766   ESTs   3.39       419317   AA236282   Hs.172318   ESTs   3.38       448710   T62926   Hs.304184   ESTs   3.37       439322   H72245   Hs.188635   ESTs   3.37       430332   R51790   Hs.239483   Human clone 23933 mRNA sequence   3.35       411755   BE327036   Hs.117494   ESTs   3.33       427882   AA640987   Hs.193767   ESTs   3.28       438899   AF085833   Hs.135624   ESTs   3.28       436535   AW295687   Hs.254420   ESTs   3.25       434936   AI285970   Hs.183817   ESTs   3.22       451730   AF095887   Hs.26937   brain and nasopharyngeal carcinoma susce   3.18       447514   AI809314   Hs.208501   ESTs, Weakly similar to B34087 hypotheti   3.18       413672   BE156536       gb:QV0-HT0368-310100-091-h10 HT0368 Homo   3.16       435073   AA664078       gb:ac04a05.s1 Stratagene lung (937210) H   3.13       450295   AI766732   Hs.210628   ESTs   3.13       419341   N71463   Hs.118888   ESTs, Weakly similar to ALU1_HUMAN ALU S   3.13       434495   AW352170   Hs.129086     Homo sapiens  cDNA FLJ12007 fis, clone HE   3.12       408113   T82427   Hs.194101     Homo sapiens  cDNA: FLJ20869 fis, clone A   3.12       456437   AI924228   Hs.115185   ESTs, Moderately similarto PC4259 ferri   3.12       421489   AI922821   Hs.32433   ESTs   3.12       436090   AI640635   Hs.116468   EST   3.11       450230   AW016607   Hs.201582   ESTs   3.11       436011   BE466173   Hs.145696   splicing factor (CC1.3)   3.09       418720   AI381687   Hs.39526   ESTs   3.09       433102   AI343966   Hs.158528   ESTs   3.08       436150   AW510927   Hs.125243   ESTs   3.05       440116   AI798851   Hs.283108   hemoglobin, gamma G   3.04       414900   AW452420   Hs.245678   ESTs   3.04       435937   AA830893   Hs.119769   ESTs   3.02       424848   AI263231   Hs.327090   EST   3.02       435354   AA678267   Hs.117115   ESTs   3.00                    
     [0356]               TABLE 23A                          Table 23A show the accession numbers for those pkeys lacking       unigeneID&#39;s for tables 1-20A, 21A, 22A, and 23A. For       each probeset we have listed the gene cluster number from       which the oligonucleotides were designed. Gene clusters were       compiled using sequences derived from Genbank ESTs and mRNAs.       These sequences were clustered based on sequence similarity       using Clustering and Alignment Tools (DoubleTwist, Oakland       California). The Genbank accession numbers for sequences       comprising each cluster are listed in the “Accession”       column.                             Pkey:   Unique Eos probeset identifier number           CAT number:   Gene cluster number           Accession:   Genbank accession numbers                         Pkey   CAT Number   Accession               413497   1373771_1   BE177661 H06215 BE144709 BE144829       413672   1382512_1   BE156536 BE156439 BE156700 BE156449               BE156653 BE156533 BE156524 BE156670               BE156721 BE156723       417670   1692163_1   R07785 T85948 T86972       418876   179960_1   AA740616 AA654854 AA229923       419145   182217_1   N99638 AW973750 AA328271 H90994               AA558020 AA234435 N59599 R94815       423974   233842_1   AL118754 AA333202 H38001       432340   345248_1   AA534222 AA632632 T81234       434966   396504_1   AA657494 AI582663 AI581639       435073   399701_1   AA664078 AW363313 AA805009       438962   467390_1   BE046594 BE046667 AA828585 AI207343       455778   1364506_1   BE088746 BE088802 BE088755 BE088876               BE088947 BE088881 BE088952       456332   179104_1   AA228357 AW841786 AW841716                    
     [0357]               TABLE 24                          34 GENES DOWN-REGULATED IN COLON CANCER       DERIVED LIVER METASTASES COMPARED TO COLON CANCER       PRIMARY TUMOR SAMPLES CLASSIFIED AS DUKE&#39;S B SURVIVOR       Table 24 shows 34 genes down-regulated in colon cancer derived liver metastases compared       to colon cancer primary tumor samples classified as Duke&#39;s B stage with a positive survival       outcome (Duke&#39;s B survivor). These were selected from 59680 probesets on the       Affymetrix/Eos Hu03 GeneChip array such that the ratio of “average” colon cancer derived       liver metastases to “average” Duke&#39;s B survivor was greater than or equal to 0.25. The       “average” colon cancer derived liver metastases level was set to the 50th percentile. The       “average” Duke&#39;s B survivor level was set to the 50th percentile.                             Pkey:   Unique Eos probeset identifier number           ExAccn:   Exemplar Accession number, Genbank accession number           UnigeneID:   Unigene number           Unigene Title:   Unigene gene title           R1:   Genes down liver metastases vs Duke&#39;s B survivors                                 Pkey   ExAccn   UnigeneID   Unigene Title   R1               414522   AW518944   Hs.76325   step II splicing factor SLU7   0.05       416768   AA363733   Hs.1032   regenerating islet-derived 1 alpha (panc   0.07       409153   W03754   Hs.50813   hypothetical protein FLJ20022   0.07       414555   N98569   Hs.76422   phospholipase A2, group IIA (platelets,   0.11       418007   M13509   Hs.83169   matrix metalloproteinase 1 (interstitial   0.11       424326   NM_014479   Hs.145296   disintegrin protease   0.11       428934   AF039401   Hs.194659   chloride channel, calcium activated, fam   0.12       417233   W25005   Hs.24395   small inducible cytokine subfamily B (Cy   0.12       422260   AA315993   Hs.105484   regenerating gene type IV   0.12       425196   AL037915   Hs.155097   carbonic anhydrase II   0.13       433336   AF017986   Hs.31386   secreted frizzled-related protein 2   0.13       450685   L15533   Hs.423   pancreatitis-associated protein   0.14       407811   AW190902   Hs.40098   cysteine knot superfamily 1, BMP antagon   0.15       414798   AI286323   Hs.97411   hypothetical protein MGC12335   0.16       452852   AK001972   Hs.30822   hypothetical protein FLJ11110   0.17       447513   AW955776   Hs.313500   ESTs, Moderately similar to ALU_HUMAN A   0.17       423541   AA296922   Hs.129778   gastrointestinal peptide   0.17       425071   NM_013989   Hs.154424   deiodinase, iodothyronine, type II   0.18       406636   L12064       gb: Homo sapiens  (clone WR4.12VL) anti-th   0.18       421515   Y11339   Hs.105352   GalNAc alpha-2, 6-sialyltransferase 1,1   0.18       428368   BE440042   Hs.83326   matrix metalloproteinase 3 (stromelysin   0.19       414812   X72755   Hs.77367   monokine induced by gamma interferon   0.20       452594   AU076405   Hs.29961   solute carrier family 26 (sulfate transp   0.20       428227   AA321649   Hs.2248   small inducible cytokine subfamily B (cy   0.21       408741   M73720   Hs.646   carboxypeptidase A3 (mast cell)   0.21       453064   R40334   Hs.89463   potassium large conductance calcium-acti   0.21       431727   AW293464   Hs.162031   ESTs   0.22       433658   L03678   Hs.156110   immunoglobulin kappa constant   0.22       442064   AI422867   Hs.88594   ESTs   0.22       417880   BE241595   Hs.52848   selectin L (lymphocyte adhesion molecule   0.22       430280   AA361258   Hs.237868   interteukin 7 receptor   0.23       452877   AI250789   Hs.32478   ESTs   0.23       410310   J02931   Hs.62192   coagulation factor III (thromboplastin,   0.24       402408               0.24                    
     [0358]                           TABLE 24B                                      Pkey:   Unique number corresponding to an Eos probeset           Ref:   Sequence source. The 7 digit numbers in this               column are Genbank Identifier (GI) numbers.               “Dunham I. et al.” refers to the               publication entitied “The DNA sequence of               human chromosome 22.” Dunham I. et al.,               Nature (1999) 402:489-495.           Strand:   Indicates DNA strand from which exons were               predicted.           Nt_position:   Indicates nucleotide positions of predicted exons.                                     Pkey   Ref   Strand   Nt_position                       402408   9796239   Minus   110326-110491                        
     [0359]               TABLE 25                          Table 25 depicts Seq ID No., UnigeneID, UnigeneTitle, Pkey, and ExAccn for all of the       sequences in Table 26. Seq ID No links the nucleic acid and protein sequence       information in Table 26 to Table 25.                             Pkey:   Unique Eos probeset identifier number           ExAccn:   Exemplar Accession number,               Genbank accession number           UnigeneID:   Unigene number           Unigene Title:   Unigene gene titie           Seq.ID.No.:   Sequence Identification Number               found in Table 26                                 Pkey   ExAccn   UnigeneID   Unigene Title   Seq ID No.               426101   AL049987         Homo sapiens  mRNA; cDNA DKFZp564F112 (fr   1-4       419145   N99638       gb   5 &amp; 6       426818   AA554827   Hs.340046   DKFZp434A0131 protein   7 &amp; 8       421057   T58283         Homo sapiens  cDNA   9       446619   AU076643   Hs.313   secreted phosphoprotein 1 (osteopontin,   10 &amp; 11       431958   X63629   Hs.2877   cadherin 3, type 1, P-cadherin (placenta   12 &amp; 13       409041   AB033025   Hs.50081   Hypothetical protein, XP_051860 (KIAA119   14 &amp; 15       443162   T49951   Hs.9029   DKFZP434G032 protein   16 &amp; 17       436385   BE551618   Hs.144097   ESTs   18-20       447033   AI357412   Hs.157601   ESTs   21 &amp; 22       439608   AW864696   Hs.301732   hypothetical protein MGC5306   23-27       449032   AA045573   Hs.22900   nuclear factor (erythroid-derived 2)-lik   28 &amp; 29       442577   AA292998   Hs.163900   ESTs   30 &amp; 31       429970   AK000072   Hs.227059   chloride channel, calcium activated, fam   32 &amp; 33       424566   M16801   Hs.1790   nuclear receptor subfamily 3, group C, m   34 &amp; 35       457407   AA505035   Hs.345911   ESTs   36       430378   Z29572   Hs.2556   tumor necrosis factor receptor superfami   37 &amp; 38       417332   AW972717   Hs.288462   hypothetical protein FLJ21511   39 &amp; 40                    
     [0360]                           TABLE 25A                                      Pkey:   Unique Eos probeset identifier number           CAT number   Gene cluster number           Accession:   Genbank accession numbers                         Pkey   CAT Number   Accession               409041       10962_2 AB033025 AL359061 AL045836 AI751521 AI752804 AI752650 AA853580 AI752290 AA853460 AI752769               AA852309 AA853785 AA853219 AW068503 AI752069 AL049389 AW068368 6E439518 W52813 BE141833 AI940574               AI750606 AL109718 AA242845 AA315795 AA307741 AW954603 AI752070 AA350794 AI752649 AA307755               AW951677 AA298896 BE439692 AA852453 AW068826 AW853984 AA418236 AA639417 AW290917 AI750592               AI752768 AL045837 AI926513 AW262903 BE439819 AI459360 AW339074 AW295181 AW029483 AI750945               AI750659 AI752525 AI147688 BE440122 AI751522 AI473816 AI752291 AI694639 AI925816 AA599476               AA242752 AW021892 AI755098 AW469299               AW769363 AA853579 AI784082 AA852454 AI925501 AA976657 AW150473 AW166734       417332   166755_1   AW972717 AA523805 AI962905 AI373245 AW235545 AI812045 AW589434 AI826824 AW572339               AI377551 AA195718 AI868470       419145   182217_1   N99638 AW973750 AA328271 H90994 AA558020 AA234435 N59599 R94815       421057   198849_1   T58283 AA765038 AA283052 H99396 AA814751 AI032674 N81016 N81017 BE222349 AA830545       424566   2408_1   M16801 NM_000901 D57171 AL041328 AF068623 AI201179 AA151766 AA568349               AI698649 AI692765 BE327401 AA744953               AA744951 AW361986 AV651840 T29894 AW945145 AW945145 W24096 AI183952 AI458972               AW190993 AI765359 AI634663 AI741201 AW418944 AI767551 AA679687 AW772342               AW629508 BE504300 AI251790 AI522294 AA724341 AW615402               AI537570 AA470665 AI458375 AW768901 AA447079 T23537 AI783744 R44301 D56621               N91919 AA149749       426101   26088_1   AL049987 AW362842 T78981 AA247541 AI217018 AW961515 AA632986 AA663108 BE326465               AW872412 AI024889 AA453725               BE150458 AA229448 AA442638 AA442648 AI916737 AA480220 AA868553 AI827987 AI005467 R31132 AI742087               AA442379 N56349 AW769479 AI860142 AI917507 AA813604 AI860141 AI459289 AA522837 AI354470 AI921333               BE466760 AW971193 AW103830 AW277065 AW020895 AI187977 N28268 AI084517 R95914 AA833517 AA563934               AA437299 AA436880 AA447794 AA812876 AA663178 R31089 AI472712 R64648 AA600372 AA229164 AA703066               AW270324 AI191725 AA551512 AA493776       426818   272427_1   AA554827 AA701001 AW972954 AL039129 AA385540 AA911663       429970   31134_1   AK000072 AW840683 AW843764 AW844444 AW844515 AW603469 AW862395 AI860838 AW511708 AF127035               NM_012128 AK000138       430378   3170_1   Z29572 AW976377 AA286871 AA633372 AA987627 AA743176 AI865358 AJ006884 AF031845 Z14955       431958   3394_1   X63629 NM—001793 BE175433 BE153414 BE153425 AW364593 BE315317 AW950190 AA314252               BE142943 AW365220 AW368405 BE004269 AW366568 AL040609 AI829273 AI591168 BE146183 AI631060               AI830793 W78081 W92295 AI927422 BE009313 AI371793 AW993031 AI204659 AA535113 AW993030               AI190281 AA555159 AW269637 AW993146 AI149268               AA425217 AW473194 AI890930 AA551993 AI952106 W92308 AI827275 W45400 AI952328 AW609233               AA774611 AA551779 AI913967 AI798658 AI537658 AW517535 AA632236 AW339148 AW589522               AA836945 AA961263 AW015821 AW272946 C00249 W40333 BE143121       436385   418907_1   BE551618 AI207338 BE220568 AI261568 AW841737 AA714722 AA946891 AI033239       439608   47438_3   AW864696 AW338889 AI342866 AA084522 AI244150 AI610339 AA425635 AA764930 AA976965               AW805766 AA057765 AW805845 AW802595 AA262971 AI969620 N75323 BE549060 AW805725 AA025809               N80776 N64595 AW073372 AA025493 AI819475 AW028879 AW189496 AA442907 AW410368 AI911629               N71276 AW316922 AW805838 AA043880 AW189184 AA449758 AA748153 AA705608 AI910643 AA279492               BE160119 AW805761 AA026262 AA782207 AW057652 AW805768               H21998 AW194254 AW275178 AA449040 AA279582 N76314 N54348       442577   54549_1   AA292998 AW238350 AI676059 AW074092 BE566458 AW078677 AW514801 AW073701 AW170620               AI523736 AI580870 AI923975 AI393326 AI700229 AW450814 AW628452 AI671457 AA937534               AI889894 AW339423 AW291875 AA551874 AI682314 AI926227 AA397375       443162   5613_1   T49951 AA025326 H04839 AA393303 R63101 W57657 W25628 AI961431 R71165 N39940               H01548 H01759 AA641624 AI634930 AA595296 AW994770 AW994747 BE047247 W38159 AA858133               AI701944 AW386273 AA676625 R24676 R79410 AA922863 AI151319 H01013 AA024482 W02674 H01456               AI150858 AW135972 AW631167 AI270332 H04750 T49622 AA004543               R63061 AI093066 AI247539 H01225 H03388 AW472933 AA382448 AI219287 N27194 AW389613               AA649738 AW994764 AW389614 R25176 AA897262 R71626 AA909471 R71240 AW811917 R76109               AI202312 AI858010 R76162 AL117538 R79411 T58658 AW994674       446619   685_1   AU076643 AA594604 AA348866 R18197 AA345192 AA337773 AA089791 R84435 AA337838 AW392167               AA075190 D55416 AW150380 AW366257 AA579816 H93048 AW385889 AW385697 AI186216 AW581197               AL037509 AB019562 AA232626 R97905 AW368019 AA242891 AW888502 AI798331 AW385835               AW581221 T96947 H87989 AA369511 AA075191 R80742 AA366406               W92752 H45588 AI864016 AW888497 BE004992 AI384110 AI624258 AI627593 W92728 AI682719               AA948208 AA171734 N40517 J04765 AA379957 AA362403 NM_000582 AF052124 AA300290               AA333447 AA343721 AW889543 BE586767 R76601 R18015 AA100531 AA489963 AA101296 AA363513               AA344088 AA336750 T77505 D56440 AL110351 AL110331 F12195 R20175 AA336664 H17766 AA363538               AA363590 D28760 AW578517 AA383531 AI814667 AA846899 AA368253 AW951285 AA297992               AA327756 AW361609 AW815455 AW815427 AW815428 D54182 AW852200 AA171630 W27018 AW815864               AW379995 AW378222 AW362610 BE566022 AW021023 C17352 D58435 AA345409 AI623991 AW020967               AI924770 AI799443 AW946393 AA991239 AI571617 AI935181 AI923999 AI826895 AI860319               AW189873 AW270353 AW023584 AI813811 R99929 AW339056 AA913152 AI636352 AI829394 AW151077               AW192580 AI570119 AI086391 AW021764 AW519154 AI375193 AW268678               BE465690 AW019983 AW268654 AI573138 AI141809 AI954553 AI559242 AA568945 AA886417               AW338527 AI635881 BE465666 AI921239 AA968537 AI958027 AA911981 AI827661 AW511046               BE619780 AI922227 AI811870 AW190131 AW129220 AW512906 AI290757 AI819088 AI623771               AA775616 BE349419 AI126375 H88773 AI241758 AW275157 AI337848               AI613425 AI631387 AA922631 AI273483 AI982898 AW168957 AI446481 BE501588 BE048264               AI499922 AW023812 BE220523 AW973846 BE349276 AI141091 AA976060 AW973845 AA101270               AI582472 AW613675 AI139360 AI282627 AI276044 N22345               AI261875 AA634136 AI824468 AW887693 N27107 R21504 AI042223 N22067 AW196871               AI581019 BE004973 AA252035 N22087 AA570717 H11250 AI804026 AA368098 AA021512               H08842 N26275 AA176368 AI758758 AA570371 AA232574               BE221177 AW190221 AW471386 AA78225 AI422140 AI624521 AA719775 AA300291 AA568657               AI871430 BE465630 N71862 T72587 W92721 H88774 D64383 AW103693 AW089986 AI382689               R42363 R44962 T98770 AA357374 AW022074 AI356207               T29241 AW089431 AI933875 N66267 N67352 AA121786 AA363910 F09824 T95818 N66888               R80550 AI280887 AW196719 R59299 AW021049 H73469 AI954311 BE439454 AW079450               AW973850 AA348338 AW896006 AW268145 AA853631 H17650               R39537 N66873 N67240 H06298 AI784199 R44260 AA904118 AA911756 F04544 AA807809               AA665210 AI696448 T29719 AA837240 T64844 H08926       447033   704603_1   AI357412 AI870708 AI590539 W07459       449032   7945_1   AA045573 AA279920 R20139 AA372783 AW963629 H21473 R78318 W74359 AA022505               AA369091 AW084075 AA503638 AV660815 AI216262 AA779843 BE219825 AF125534               AW972129 AI919099 AI621283 AI300590 AI953701 AA331415 AW610546               AW793050 AI953679 AW793047 AW610543 AI671103 AW292105 AW024112 R77947               W76339 AA305111 AA132523 AA227467 H21401 AW366572 AW024129 AI701886 AI654744               BE042803 AI347173 AW866053 AW662710 R36639 AI469777 AA962733               AI865368 AA501998 AW866054 BE178974       457407   333252_1   AA505035 AW235098 AI634028                    
     [0361]                       TABLE 26                          Seq ID NO: 1 DNA sequence               Nucleic Acid Accession #: see Table 25 &amp; 25A for complete list               1    11    21    31    41    51       |   |   |   |   |   |       CAATATAGTA CAATAACTAT TTGCATGACA TTTACATCGG ATATTATGAG TGATCTAGAG   60               TTGATATGAA GTATATGGGA GGATGTGCAA AGGTGATGTG CAAATACTAT GTCATTTTAT   120               AGGGGGGACT TGAGTATCCT TTGTTACCCT CAGGAGATCC TGAAACCAGT CCCCCATGGA   180               TACTGAGGGC TGACTGTATA GTCCTATCCT CACGGAACTT TCATTCTAAT GGGGGAAGAC   240               TGACTATAAA CAAAATATAT GTAATAGGTG GTGGTAAGTA CCGTGGAGAA GTAACAAATG   300               GGGCAAAGTG AGTTATACAG CTCCATTCTT AGAAACCTTG GAGTACTTTT CTTAGTTTAT   360               ACTCGTGGTG GTTTCCTTTT GTCTCCTTTA TTACATGGGA CTCTGACATG TGCCCATAGC   420               TAGGGTGACA GTAGGATCTA CCCGATAGTA GGGTGGCAGT AGGATCTACC CAAAAAGCGT   480               CCTGCTGATA CAGGACCAAA GCATCCTGTT GTTCTCGAGC CTATAAAAAG AGCTAATGGT   540               GTTGCTTCTC TTAACTGTGG CCTCCTACAC TGTGTTTTGG ATGATTGGTG ATGTCTTGGA   600               TATTCTGTTT CTTTGGAACT TTGAATATAC AACACTTTAC TAGGGAATTA GCAATGGAAG   660               CAGAGCAAAG ATGTACAGAG GAAACAATGC GTAACTCTGA TGGAATTGAA GTCATGAGGC   720               AGCAGAGAGC TTAAATTACA GCTTTAAAAA TTTTTATTTT TTAGAGGGAA TTTACTTGGG   780               AGTAACAGCA GTAATAGTTA ACGGAGCCAG AATGCTTGAG TCATATAATT GCAAAGCAGA   840               GTTGGGAGCA ACAGATGCTA AAGAGTAGTT GCTGTAGTTC CTCTTTGGGT CGTAGGAGCA   900               GTTGTCATAT TACTATATAG CTACTGCATG AAGAAGAGTT CTTAGTGAGG CCTGGGTGAA   960               CAGCTCTTCT TAGTATTCTG TGTGACCCCA TTTGACCTTT TAACAAATCC CTAAGTAAAT   1020               AAATAGCCCC TCAGGAAAAC TAAGTTTTTC TCTGCTGTTT TTTTGCTTGA GAGAGCTATA   1080               ACTGTAATAG ACTTATATTT CTGAACATTT TAGTGCTTGC CAATATTTGG TAATATTTAT   1140               GTTTCCTATA TTTGTAATGA ACATTCTTCT TCCGGTACAT TTTTTGTTAA ATTATTGTTT   1200               GATGGATAAA AGTTCACCTT TTATTGTATA AAATTGACTG AGATTAATTT ATACACATTG   1260               ACAATGGGTA AATAGAATTT TTCAGATTAT TAAAAGCTGA AGGATGACCA CGTAAGCAAA   1320               AAAAAAAAAA AAAAAACCAA CAAAAATAAA CCCAAACCCC TCAAACAATT TCGAACACGA   1380               AACATTCTTC TGATGCCGGC ATCCCTGCTT GCAGGTGTGA AGGGGGCAGG AATCAGCGAG   1440               GTGTCCTGGG CTGAGTCCCC GGGGAAGAAT ATGAT               Seq ID NO: 2 DNA sequence       Nucleic Acid Accession #: X83301.1               1   11   21   31   41   51       |  |   |    |   |   |       GCAAAGCCAG CTGGGCTCCT GAGTCCGGTG GGTACTTGGA GAACTTACTA CGTCTAGCTG   60               GAGGATTGTA AATGCACCAA TCAGCATGCT GTGTCTAGCT CAAGATTTTC TCCATCCCCT   120               TATTTTGGGC CAGTGGCTGT CATTACATAT GAGATGAGTC TCTTGAAGAC TACAGATGAA   180               CTCAAGCTCC ATGAGGAGAT GTTTCATTGT CGAGAGCAGT CATGATGGCC TGCACTCCAC   240               ACAATGCAAC AGAGTGAAAG AGCAGGTTCT GCTTCTTTGG TGTAGTCCTG AAGCTTCCTA   300               AGAAACTTCA CATCAGGTGA TGGATAGGAG CAACCCTGTA AAACCAGCCT TAGACTATTT   360               TTCAAACAGG CTGGTGAATT ACCAGATCTC CGTCAAGTGC AGTAACCAGT TCAAGTTGGA   420               AGTGTGTCTT TTGAATGCAG AGAACAAAGT CGTGGACAAC CAGGCTGGGA CCCAGGGCCA   480               GCTGAAGGTG CTGGGTGCCA ACCTCTGGTG GCCGTACCTG ATGCACGAAC ACCCCGCCTA   540               CCTGTACTCC TGGGAGGATG GTGATTGCTC ACACCAAAGC CTTGGACCCC TCCCAGCCTG   600               TGACCTTTGG GACCAACTCC ACCTACGCAG CAGACAAGGG GGCTCTGTAT GTGGATGTGA   660               TCCGTGTGAA CAGCTACTAC TCTTGGTATC GCAACTACGG GCACCTGGAG TTGATTCGGC   720               TGCAGCTGGC CGCCCAGTTT GAGAATTGGT GTGAGACATC ACAATCCCAT TATTCAGAGC   780               GCGTATGGAG TGGAAACGCT TGTAGGGTTT CACCAGGGCT GGTGAATTAC CAGATCTCCG   840               TCAAGTGCAG TAACCAGTTC AAGTTGGAAG TATGTCTTTT GAATGCAGAA AACAAAGTCG   900               TGGACAACCA GGCTGGGACC CAGGGCCAGC TGAAGGTGCT GGTGCCAACC TCTGGTGGCC   960               GTACCTGATG CACGAACACC CCGCCTACCT GTACTCGTGG GAGGATGGTG ATTGCTCACA   1020               CCAAAGCCTT GGACCCCTCC CAGCCTGTGA CCTTTGGGAC CAACTCCACC TACGCAGCAG   1080               ACAAGGGGGC TCTGTATGTG GATGTGATCC GTGTGAACAG CTACTACTCT TGGTATCGCA   1140               ACTACGGGCA CCTGGAGTTG ATTCGGCTGC AGGCCCTGCA GCTGGCCGCC CAGTTTGTGA   1200               ATTGGTGTAA GACATCACAA TCCCATTATT CAGAGCGCGT ATGGAGTGGA AACGCTTGTA   1260               GGGTTTCACC AGTCTTTCCC AGGGAACTCC GATGAAGTGT TCCAACAAAA TGAGCGAGTG   1320               AACCAAGAAG AGGATGACAT TAGATCCAGG AGATACAACA GAGGAGATAA TCTCCAGGAT   1380               GCCTGTGAAG AAAGATCCCT GGATCCCAGG ATGATTATAG GACAAGTTGT TCATAATCCA   1440               GCAGGCCAGA AGACTTCCAG GGAAACTCAT TTCAAGATGA AAATGGACCA GCCGCAGTGG   1500               CTCACGCCTG TAATACCAGC ACTTTGGGAG GCTGAGGCGG GCGGATCACT TGAGGTCAAG   1560               AGTTTGAAAC TAGCCTGGCC AACGTGGCAA AACTCCATCT CTATTAAAGA TACAAAAATT   1620               AGCCAGGCAT AGTGGTGCAT GCCTGTAGTC CCAGCTACTT GGGATGCTGA GGCAGGAAGA   1680               ATTGCTTGAA CCTGGGAGGC AGAGTCTGCG GTGACCGAGA TCATGCCACT GCACTCCAGC   1740               CTGGGTGACA GAGCCAGACT CCGTCTCTAC TAAAAAAAAA AAAAAAAAAA AAA               Seq ID NO: 3 Protein sequence:       Protein Accession #: CAA58280.1               1   11   21   31   41   51       |  |   |    |   |   |       MDRSNPVKPA LDYFSNRLVN YQISVKCSNQ FKLEVCLLNA ENKVVDNQAG TQGQLKVLGA   60               NLWWPYLMHE HPAYLYSWED GDCSHQSLGP LPACDLWDQL HLRSRQGGSV CGCDPCEQLL   120               LLVSQLRAPG VDSAAAGRPV               Seq ID NO: 4 DNA sequence       Nucleic Acid Accession #: BC002622.1               1   11   21   31   41   51       |  |   |    |   |   |       GGCACGAGGC TCCGCCCGCG GCCGGGATGC ACTAGGCAAA GCCAGCTGGG CTCCTGAGTC   60               CGGTGGGTAC TTGGAGAACT TACTACGTCT AGCTGGAGGA TTGTAAATGC ACCAATCAGC   120               ATGCTGTGTC TAGCTCAAGA TTTTCTCCAT CCCCTTATTT TGGGCCAGTG GCTGTCATTA   180               CATATGAGAA CTCAAGCTCC ATGAGGAGAT GTTTCATTGT CGAGAGCAGT CATGATGGCC   240               TGCACTCCAC ACAATGCAAC AGAGTGAAAG AGCAGGTTCT GCTTCTTTGG TGTAGTCCTG   300               AAGCTTCCTA AGAAACTTCA CATCAGGTGA TGGATAGGAG CAACCCTGTA AAACCAGCCT   360               TAGACTATTT TTCAAACAGG CTGGTGAATT ACCAGATCTC CGTCAAGTGC AGTAACCAGT   420               TCAAGTTGGA AGTGTGTCTT TTGAATGCAG AAAACAAAGT CGTGGACAAC CAGGCTGGGA   480               CCCAGGGCCA GCTGAAGGTG CTGGGTGCCA ACCTCTGGTG GCCGTACCTG ATGCACGAAC   540               ACCCCGCCTA CCTGTACTCG TGGGAGGATG GTGATTGCTC ACACCAAAGC CTTGGACCCC   600               TCCCAGCCTG TGACCTTTGT GACCAACTCC ACCTACGCAG CAGACAAGGG GGCTCTGTAT   660               GTGGATGTGA TCCGTGTGAA CAGCTACTAC TCTTGGTATC GCAACTACGG GCACCTGGAG   720               TTGATTCAGC TGCAGCTGGC CGCCCAGTTT GAGAATTGGT GTAAGACATC ACAATCCCAT   780               TATTCAGAGC GCGTATGGAG TGGAAACGCT TGTAGGGTTT CACCAGTCTT TCCCAGGGAA   840               CTCCGATGAA GTGTTCCAAC AAAATGAGCG AGTGAACCAA GAAGAGGATG ACATTAGATC   900               CAGGAGATAC AACAGAGGAG ATAATCTCCA GGATGCCTGT GAAGAAAGAT CCCTGGATCC   960               CAGGATGATT ATAGGACAAG TTGTTCATAA TCCAGCAGGC CAGAAGACTT CCAGGGAAAC   1020               TCATTCAAGG AGGTGAAAAT GATGGATGAC TCCTCCAAGA TGAAAATGGA CCAGCCGCAG   1080               TGGCTCACGC CTGTAATACC AGCACTTTGG GAGGCTGAGG CAGGCGGATC ACTTGAGGTC   1140               AGGAGTTTGA AACTAGCCTG GCCAACGTGG CAAAACTCCA TCTCTATTAA AAATACAAAA   1200               ATTAGCCAAG CATAGTGGTG CATGCCTGTA GTCCCAGCTA CTTGGGATGC TGAGGCAGGA   1260               AGAATTGCTT GAACCTGGGA GGCAGAGTCT ACAGTGAGCC GAGATCATGC CACTGCACTC   1320               CAGCCTGGGC AACACAGTGA GACTCCATCT CAAAAAAAAA AAAAAAAAAA AA               Seq ID NO: 5 Protein sequence:       Protein Accession #: AAH02622.1               1   11   21   31   41   51       |  |   |    |   |   |       MDRSNPVKPA LDYFSNRLVN YQISVKCSNQ FKLEVCLLNA ENKVVDNQAG TQGQLKVLGA   60               NLWWPYLMHE HPAYLYSWED GDCSHQSLGP LPACDLCDQL HLRSRQGGSV CGCDPCEQLL   120               LLVSQLRAPG VDSAAAGRPV               Seq ID NO: 6 DNA sequence       Nucleic Acid Accession #: see Table 25 &amp; 25A for complete list               1   11   21   31   41   51       |  |   |    |   |   |       ACCTGAGATC AGGAGTTCGA GATCAGCCTG ACCAATAGGG TGAAACCCCG TCTCTACTAA   60               AAATACAAAA AATTAGCTGG ACACGATGGT GGGTGCCTGT GGTCCCGGCT ACTCGGGAGG   120               CTGAGACAGG AGAATCAGTT GACCTGGGAG TTGGTGGTTG CAGTGAGCTG AGATCACACC   180               ATTGCATTCC AAGCCTGGGC AACAAGAGTG AAACTCCATC GCAAAAAAAA AAAAGAAGGG   240               GCATAATTTG TGGATGAGGA TTGGATATAA GGTAAAGGAT GGGACATTCT TGGACTTACA   300               GATGGTGTGA TTGCCTGGCT AGAAGAAGAA TTCCCGGTCA AAAAGAAACC ATCAGCTTTC   360               CAAGTGTGAA AGAGAGATAA ATCTGTGAAG ATTATAGGGA CTACAGGAAA CTTAATCTTT   420               TTCTTTGAAA AAGCAATTGT AGCAAAAAAA AAGAAAATTT CTTACTGTCA TCTAAAATTG   480               ACATGGACAT CTTAGTGGAC TAGAAGTTAA GGGCATAAAT TCTCCCAGTG ATTTTTAATT   540               TTAGCATTGT GATTAACACC TTCTAAAATT GCCAGAACTT AATAAATAAT TGCTTTTCAT   600               TATTAGTATG CCATCAAATT TAGTAGCTGT TTCAGGCTTT AATGTGTCAA GCCTAAAATC   660               CAGATTTTTG AGGATCTTCT CCCTCTTAAA AGAGTATTCA GTTAACTGCC GTAGAAATAC   720               ACATGTATAC AAGGGCACTG TATACATCAG TCTAAAAAAT AAAAATATGT ATACGTTCTG   780               GTGAGTCTAG CACAGCATTG CCCAATAGAA ATACCAATGG AGGTCACAAA TGTGGCCCAT   840               ATAGGTTAAT TGGTAAATTT TCTNATAGNC ACC               Seq ID NO: 7 DNA sequence       Nucleic Acid Accession #: AK000942       Coding sequence: 1204-1503               1   11   21   31   41   51       |  |   |    |   |   |       GTAAAGGAAT GTCTTTTTAA TTCAGCTTTT CTTTTCTCCA TGCTAGTGTT ATCAGGTTTT   60               GGTATTTATT TACTTACAGC ATATGTTATG AAGCTGGTTT GAAAATTGGT TTTAGATATA   120               TCTGCAAGTT TACTACTTTG ACTGTAAAAA AAAAAAATGA AAAAGTAGTT GACATCTGTC   180               CTCAGAAGAA GTTTGCAGGT TGCATATTTG TGTGTAAATA CACAGGCTAA AAGGTAATTT   240               ATGTTCCTTG GGAATTGAAA TGGTCAGTGG CCCGTTACAG AAACTTATCA GTCATATATC   300               AGCACCAGTT CATTCTTTTG CACCTTAGGG ACCATCTGTC CCCTGAGGTG ACCTGAGAAA   360               CAACCAGTTG CCCACAGACT GTTATTTCTT CAAGTGAGCC AGGATTTGAT TTCACTGCCT   420               TATATTCTAT TTTTAGTGTA CAGTGCTTTG ATTTTTTGGA AAAACTAAAT TTTAAACATA   480               TTTGAAAAAT GTTATAAGAC TTGGACATTA AGTCTGTTGA TAGCCAAAGT CAGTTTACCA   540               AAGTAAAACA AATAAATTCT ATGCTTCTTC ATTGTCAAAG AGCAGTCTGC CATCATGTGG   600               ATATAAATGG ACTATGTAAA GTGACATGGT GCTTACTCTC TACCTAATAA TAGCCTCCCT   660               CCTGTTCCAA CAAGATAACC AACAGGTATA TTTAATTTAC CAGTTAATAT GTTTTGGATA   720               ATTGGCTGCC TTGAAATGCT ATATGTTTTA TAGTACATCA TAGCTTTAGT TTTCTTCATA   780               AGGAAATTAC AGTTACATCC TGGCTAACAT GGTGAAACTC CATCTCTACT AAAAATACAA   840               AAAATTAGCC GGGCGTGGTG GCGGGCACTT GTAGTCCCAG CTACTCGGGA GGCTGAGGCA   900               GGAGAATGGC GTGAACCCAG GAGGCGGAGG TTGCAGTGAG CCGAGATCGT GCCACTGTAC   960               TCTGGCCTGG GAGACAGAGC GAGACTCCAT CTCAAAAAAA AAAAAAAAAA AAAAAAAAGA   1020               GAGAGAGAGA CCTGGAGTAG AGATTCTGTC AAAGAACTTT TTCTTTCTTG AGAAGCATCT   1080               GAAATGGAAT CTGTTGTCTC TTCGAAATAT GTACTGCTGT AACAGTGAAA CAACCCTCAG   1140               AGTATGCCTT CGTGTGGGCT ACTCGTTGTG GTTTTGAACT TGGGGGAACT GTCTGTGTTT   1200               GGGTCAAGAA TATGCAACTG GCTGGGCACA TTGGCTCACG CCTGTAATCC CAGCAATTTG   1260               GGAGGCTGAG GCAGGCGGAT CACCTGAGGT CAGGGCTTCA AGACCAGACT GGCCAACATG   1320               GTGAAACCCC GTCTCTACTG AAAATACAAA AATTAGCTGG GCATGGTGGC AGGTGCCTGT   1380               AATCCCAGCT ACTCGGGAGG CTGACGTGAG AGAATCGCTT GAACCCGGGA GTTGGAGGTT   1440               GCAGTGAGCC GAGATTGCAC CATTGCACTC CAGCTTGGGC AACAAGAGTG AAACTCTTGT   1500               CTCAG               Seq ID NO: 8 DNA sequence       Nucleic Acid Accession #: see Table 25 &amp; 25A for complete list               1   11   21   31   41   51       |  |   |    |   |   |       GACTAGGCTG GGCAACATAG TGAGACCTCA TCTCTAAAAT TAAAAAAATA AAAGCCACCA   60               GAAAAAAACC TAAAAACATG CCAAGTGACA TCAGTCTTTG ATGAAAATGG CAGCAGAAGA   120               GTGATGCCAT GGGTGGGGGT GGGAAATGCT ATTTCAGCAG AGAGGGAGCT GTCATGGAAG   180               ACACCATGTG GCTGGGCACG GTGGCTCACA CCTGTAATCC CAGCACTTTG GGAGATAGAG   240               GCAGGTGGAT CCCTTGAGCT TAGGAATTTG AGACTAGCCT GGGCAATAAG AGTGAAACTC   300               CATCTCAAAA AAAAAAAAAA AAAAAGGTGC ATGAAACATA TGAAGCAAAA AGTGAAAGTC   360               CCCATTCTTT TCCTTTTTCC AGAGGTGATT TTTGTGGCCA ATCTGGTTTC ATTCCCTCCC   420               AGACACTTTT CTAGGCATCT ATGCGCCTCT ATTCACATAT AAACAAAATA GGAGTTTTCC   480               TGTGCTTCCC TTAAATGGCA TATGTATCTT TCACTCTTTT TTTTCACCTA GTGGATCTTT   540               AATACCTTAA AAGCTCAACC TGGGCTTGGT GCGGTGGCTC ATACGTGTAA TCCCAGGCCT   600               TTGGGAGGCC AAGGTGGGAG GATCACTTGA GCTCAGGAGT TCCAGACCAT TCCAAAGCAA   660               AAACAAAAGG ATTTTGAGAT CAGTGTGGGC AACTTAGCAA AACACCATCT CTTAAAAAAA   720               AAAAAAAAAA               Seq ID NO: 9 DNA sequence       Nucleic Acid Accession #: BC010433.1       Coding sequence: 3-335               1   11   21   31   41   51       |  |   |    |   |   |       GGTCGCCCTC CGTCGTGGTC TGGCGTGTAT TCCGAGCCTT GGTGTCTGGC GGTTTCCGAG   60               CGTTGGTGTC TGGCGGTTTC CGAGCGTTGG TGTCTGGCGG TTTCCGACCG TTGGTGTCTG   120               GCGGTTTCCG ACCGTTGGTG TCTGGCACGC GCCACCCTCT CTTGCTTTGG TTGCGCCATG   180               CCGATGTACC AGACAAGAAG ACAAGAAAAT GATTTGAGGA CAGCTTCAAT CGCGGTGTGA   240               AGAAGAAAGC AGCAAAACGA CCACTGAAAA CAACGCCGGT GGCAAAATAT CCAAAGAAAG   300               GGTCCCAAGC GGTACATCGT CATAGCCGGA AACAGTCAGA GCCACCAGCC AATGATCTTT   360               TCAATGCTGC GAAAGCTGCC AAAAGTGACA TGCAGCACCG AGAAGTCCGC GTGAAGTGCG   420               TGAAGGCTCT GAAAGGGCTG TACGGTAACC GGGACCTGAC CGCACGCCTG GAGCTCTTCA   480               CTGGCCGCTT CAAGGACTGG ATGGTTTCCA TGATCATGGA CAGAGAGTAC AGTGTGGCAG   540               TGGAGGCCGT CAGATTACTG ATACTTATCC TTAAGAACAT GGAAGGGGTG CTGATGGACG   600               TGGACTGTGA GAGCGTCTAC CCCATTGTGT AGGCCTCTAA TTGAGGCCTG GCCTCTGCTG   660               TGGGTGAATT TCTGTACTGG AAACTTTTCT ACCCTGAGTG CGAGATAAGA ACGATGGGTG   720               GAAGAGAGCA ACGCCAGAGC CCAGGTGCCC AGAGGACTTT CTTCCAGCTT CTGCTGTCCT   780               TCTTTGTGGA GAGCAAGCTC CACGACCACG CTGCTTACTT AGTAGACAAC CTGTGGGACT   840               GTGCAGGGAC TCAGCTGAAG GACTGGGAGG GTCTGACAAG CCTGCTGCTG GAGAAGGACC   900               AGAGCACGTG CCACATGGAG CCAGGGCCAG GGACCTTCCA CCTCCTAGGG TGAAACCAGG   960               AGAGATTGCT TGCTTCACTT GTACAAGGCA GGAACGGTGG CATGGGGTGG GGGAAACTTG   1020               GAGTTGGAAG GTGGCTAATC TTTGATTCTA TGTTTTTGAT CCTCCTGGCA CTCCAGACCT   1080               GGGTGATGTG CAGGAGAGCA CACTGATAGA AATCCTTGTG TCCAGTGCCC AGCAACTCCT   1140               GCCTCAGCCT CCCGAGCAGC TGGGACTACA GGCGCCCGCC ACCACGCCTG GCTAACTTTT   1200               TTGTGTTTTT AGTAGAGACG GGTTTTCACC GTGTTGGCCA GGATGGTCTT GATCTCTTGA   1260               CCTTGTGATC CACCTGCCTC ATCATCCCAA AGTGCTGGGA TTACAGGCGT GAGCCACTGC   1320               GCCCAGCATG TTAGACAATT TTTAATTCAT CCTCTCTGTG CTGTTGTTTT CTCAGCTGTG   1380               AAAGGAATAT TCTGGTGGGG ACAAGGTTAC AGAGTTGCTG AGAGGGTCTC ATGACATGAA   1440               GGTACTGGCC TTGGCACAGT GCCTGGGGGG GCGGGGACTC CGCACATGCC TGTGATGTCA   1500               CAGTTACTGT CAGTTCACAG CGAACCTTCC CTCCTTTTCC TGTTGACTTT CCCACACTCC   1560               TGTAACCCTC CCTCCCTCCC TTCTTCCTCT CTCTCTCTCT CACTCACGCA CACGCACACA   1620               CACACACACA CACACACACA CACACACTCC ATTCACTGTC TCCATGACTC TGGAGTAAAC   1680               TAACGTCTCG AGTFGCCATT GGAAGCCCCG TTGTCCTCAT TTAGACTTTC ATGGGTTATA   1740               GGCACTTTTG ACTTCCTGGG GTCCTTCTTC AGTTAAAAAA AAAAATTAGA AAATTAGGCC   1800               GGGCGTGGTG GCACATGCCT GTAATCCCAG CACCTTGGCC TCCCAAAGTG CTGGGATTAC   1860               AGGAGTGAGC CACCATGCCC AGCCTCCGTT GTCCTCATTT AGACTTTCAT GGGTTATAGG   1920               CACTTTTGAC TTCCTGGGGT CCTTCTTCAG TTAAAAAAAA AAAAAAAAAA               Seq ID NO: 10 DNA sequence       Nucleic Acid Accession #: see Table 25 &amp; 25A for complete list               1   11   21   31   41   51       |  |   |    |   |   |       AGTGGNTCCC CCGGNCTGCA GGAATTCGGC ACGAGATCAT GATGGCTAAT ATTTCCTGAG   60               CACCTTTCAT TCAGGCATGA TGCCAGGTGC ACCAACTTAC TTAATCCTCA TAGCCACCAC   120               CTGAGCAAGC TCCTGTTTTA TAAATGGACC AGTTCTTGTT GCTGTTGTAC AAGTTATTTT   180               CTTTCTATAA CGTCCTCCTT GTCCTCCTTC CACATTCTTA AAGAAACTTT CCCTTCCTTT   240               AAAGTACTCA GGGAGCCCTG CATTGCTTCT TGAAGCCTTC TCCAGCTTCA TCATCTCACA   300               GTGGTCTCTC TTETCACTAA ATGTCCAATA TGCTGCACAT AAGTACCCCA AAGTTAGCAC   360               AGGAATTGTT CCATGGCTGT CATATATGTT AAAAATCATT AAAAGTTCAT TTTTTCTCTC   420               ATTATGGGAA GGATACATGC TCCTACTAGT AAATTTAGTA GGTAGAAAAA AATTATCACT   480               ATCTAGACTG CTTTCCATTT AGTCTTTATG CATAGCTTTC GTGTCTGCCT ATTTTTACCT   540               TGTGTTTGTA ACTTACTATT ATAAAATATG CGTCTCTATG TTCATTGTCA ACGATTATTT   600               ACAATAACAT GGAGTGGATT TACATGTATT CTCTATATTT GGATTAAAGG AGATAGAGTA   660               TGTGAAATTA AATGGGAGAA GTATCTGATA CATAACAGGC AATACAAATA TTATCACATA   720               GCGTCAATTT ATTTGTGAAT ATTGAAAGCT CCAAAAAAGA AAAAAAGTTT TTTTTTAATT   780               CCCGTAATTA CTTATTGCAG TATTGTGTTC ATACAAACTG CTCAGTCATT TTGGAGAAAT   840               AACAATTTTT TTCCTCATCA TGAAGTAAGG TATGCTCACT GCAAAAAAAA TCTAGAAAAT   900               AAAGAGGAAC ATGCTAAAGA AAAGAATACT CCCATATAAT CTCTGTCTTC ATAAATAATC   960               TTTTGTAACG CTTATACACT GCTGGTGGGA ATGTAAATTA GTTCAGCCAT TGTGAAAAGT   1020               AGCGTAGCAA TTCCTTGAAA AACTTAAAAT AGATTTACCG TTCAACCCAG CAATCCCATT   1080               ATTGGGCATA TACCCAGTGG AATGTAAATC ATCCTGCCAT AAAAACACAT GCACATGTAT   1140               GTTCATTGCA GCACTATTCA CAATAGCAAA GACATGGAAT CAACCTATAT GCCCATCAAT   1200               AGTAGACTGA ATAAAGAAAA TATGGTACAT ATTCACCACA GAATACTAAG CAGCCATAAA   1260               AAAAAA               Seq ID NO: 11 DNA sequence       Nucleic Acid Accession #: NM_000582.1       Coding sequence: 88-990               1   11   21   31   41   51       |  |   |    |   |   |       GCAGAGCACA GCATCGTCGG GACCAGACTC GTCTCAGGCC AGTTGCAGCC TTCTCAGCCA   60               AACGCCGACC AAGGAAAACT CACTACCATG AGAATTGCAG TGATTTGCTT TTGCCTCCTA   120               GGCATCACCT GTGCCATACC AGTTAAACAG GCTGATTCTG GAAGTTCTGA GGAAAAGCAG   180               CTTTACAACA AATACCCAGA TGCTGTGGCC ACATGGCTAA ACCCTGACCC ATCTCAGAAG   240               CAGAATCTCC TAGCCCCACA GACCCTTCCA AGTAAGTCCA ACGAAAGCCA TGACCACATG   300               GATGATATGG ATGATGAAGA TGATGATGAC CATGTGGACA GCCAGGACTC CATTGACTCG   360               AACGACTCTG ATGATGTAGA TGACACTGAT GATTCTCACC AGTCTGATGA GTCTCACCAT   420               TCTGATGAAT CTGATGAACT GGTCACTGAT TTTCCCACGG ACCTGCCAGC AACCGAAGTT   480               TTCACTCCAG TTGTCCCCAC AGTAGACACA TATGATGGCC GAGGTGATAG TGTGGTTTAT   540               GGACTGAGGT CAAAATCTAA GAAGTTTCGC AGACCTGACA TCCAGTACCC TGATGCTACA   600               GACGAGGACA TCACCTCACA CATGGAAAGC GAGGAGTTGA ATGGTGCATA CAAGGCCATC   660               CCCGTTGCCC AGGACCTGAA CGCGCCTTCT GATTGGGACA GCCGTGGGAA GGACAGTTAT   720               GAAACGAGTC AGCTGGATGA CCAGAGTGCT GAAACCCACA GCCACAAGCA GTCCAGATTA   780               TATAAGCGGA AAGCCAATGA TGAGAGCAAT GAGCATTCCG ATGTGATTGA TAGTCAGGAA   840               CTTTCCAAAG TCAGCCGTGA ATTCCACAGC CATGAATTTC ACAGCCATGA AGATATGCTG   900               GTTGTAGACC CCAAAAGTAA GGAAGAAGAT AAACACCTGA AATTTCGTAT TTCTCATGAA   960               TTAGATAGTG CATCTTCTGA GGTCAATTAA AAGGAGAAAA AATACAATTT CTCACTTTGC   1020               ATTTAGTCAA AAGAAAAAAT GCTTTATAGC AAAATGAAAG AGAACATGAA ATGCTTCTTT   1080               CTCAGTTTAT TGGTTGAATG TGTATCTATT TGAGTCTGGA AATAACTAAT GTGTTTGATA   1140               ATTAGTTTAG TTTGTGGCTT CATGGAAACT CCCTGTAAAC TAAAAGCTTC AGGGTTATGT   1200               CTATGTTCAT TCTATAGAAG AAATGCAAAC TATCACTGTA TTTTAATATT TGTTATTCTC   1260               TCATGAATAG AAATTTATGT AGAAGCAAAC AAAATACTTT TACCCACTTA AAAAGAGAAT   1320               ATAACATTTT ATGTCACTAT AATCTTTTGT TTTTTAAGTT AGTGTATATT TTGTTGTGAT   1380               TATCTTTTTG TGGTGTGAAT AAATCTTTTA TCTTGAATGT AATAAGAATT TGGTGGTGTC   1440               AATTGCTTAT TTGTTTTCCC ACGGTTGTCC AGCAATTAAT AAAACATAAC CTTTTTTACT   1500               GCCTAAAAAA AAAAAAAAAA AAAA               Seq ID NO: 12 Protein sequence:       Protein Accession #: NP_000573.1               1   11   21   31   41   51       |  |   |    |   |   |       MRIAVICFCL LGITCAIPVK QADSGSSEEK QLYNKYPDAV ATWLNPDPSQ KQNLLAPQTL   60               PSKSNESHDH MDDMDDEDDD DHVDSQDSID SNDSDDVDDT DDSHQSDESH HSDESDELVT   120               DFPTDLPATE VFTPVVPTVD TYDGRGDSVV YGLRSKSKKF RRPDIQYPDA TDEDITSHME   180               SEELNGAYKA IPVAQDLNAP SDWDSRGKDS YETSQLDDQS AETHSHKQSR LYKRKANDES   240               NEHSDVIDSQ ELSKVSREFH SHEFHSHEDM LVVDPKSKEE DKHLKFRISH ELDSASSEVN               Seq ID NO: 13 DNA sequence       Nucleic Acid Accession #: NM_001793       Coding sequence: 71-2560               1   11   21   31   41   51       |  |   |    |   |   |       AAAGGGGCAA GAGCTGAGCG GAACACCGGC CCGCCGTCGC GGCAGCTGCT TCACCCCTCT   60               CTCTGCAGCC ATGGGGCTCC CTCGTGGACC TCTCGCGTCT CTCCTCCTTC TCCAGGTTTG   120               CTGGCTGCAG TGCGCGGCCT CCGAGCCGTG CCGGGCGGTC TTCAGGGAGG CTGAAGTGAC   180               CTTGGAGGCG GGAGGCGCGG AGCAGGAGCC CGGCCAGGCG CTGGGGAAAG TATTCATGGG   240               CTGCCCTGGG CAAGAGCCAG CTCTGTTTAG CACTGATAAT GATGACTTCA CTGTGCGGAA   300               TGGCGAGACA GTCCAGGAAA GAAGGTCACT GAAGGAAAGG AATCCATTGA AGATCTTCCC   360               ATCCAAACGT ATCTTACGAA GACACAAGAG AGATTGGGTG GTTGCTCCAA TATCTGTCCC   420               TGAAAATGGC AAGGGTCCCT TCCCCCAGAG ACTGAATCAG CTCAAGTCTA ATAAAGATAG   480               AGACACCAAG ATTTTCTACA GCATCACGGG GCCGGGGGCA GACAGCCCCC CTGAGGGTGT   540               CTTCGCTGTA GAGAAGGAGA CAGGCTGGTT GTTGTTGAAT AAGCCACTGG ACCGGGAGGA   600               GATTGCCAAG TATGAGCTCT TTGGCCACGC TGTGTCAGAG AATGGTGCCT CAGTGGAGGA   660               CCCCATGAAC ATCTCCATCA TCGTGACCGA CCAGAATGAC CACAAGCCCA AGTTTACCCA   720               GGACACCTTC CGAGGGAGTG TCTTAGAGGG AGTCCTACCA GGTACTTCTG TGATGCAGGT   780               GACAGCCACG GATGAGGATG ATGCCATCTA CACCTACAAT GGGGTGGTTG CTTACTCCAT   840               CCATAGCCAA GAACCAAAGG ACCCACACGA CCTCATGTTC ACCATTCACC GGAGCACAGG   900               CACCATCAGC GTCATCTCCA GTGGCCTGGA CCGGGAAAAA GTCCCTGAGT ACACACTGAC   960               CATCCAGGCC ACAGACATGG ATGGGGACGG CTCCACCACC ACGGCAGTGG CAGTAGTGGA   1020               GATCCTTGAT GCCAATGACA ATGCTCCCAT GTTTGACCCC CAGAAGTACG AGGCCCATGT   1080               GCCTGAGAAT GCAGTGGGCC ATGAGGTGCA GAGGCTGACG GTCACTGATC TGGACGCCCC   1140               CAACTCACCA GCGTGGCGTG CCACCTACCT TATCATGGGC GGTGACGACG GGGACCATTT   1200               TACCATCACC ACCCACCCTG AGAGCAACCA GGGCATCCTG ACAACCAGGA AGGGTTTGGA   1260               TTTTGAGGCC AAAAACCAGC ACACCCTGTA CGTTGAAGTG ACCAACGAGG CCCCTTTTGT   1320               GCTGAAGCTC CCAACCTCCA CAGCCACCAT AGTGGTCCAC GTGGAGGATG TGAATGAGGC   1380               ACCTGTGTTT GTCCCACCCT CCAAAGTCGT TGAGGTCCAG GAGGGCATCC CCACTGGGGA   1440               GCCTGTGTGT GTCTACACTG CAGAAGACCC TGACAAGGAG AATCAAAAGA TCAGCTACCG   1500               CATCCTGAGA GACCCAGCAG GGTGGCTAGC CATGGACCCA GACAGTGGGC AGGTCACAGC   1560               TGTGGGCACC CTCGACCGTG AGGATGAGCA GTTTGTGAGG AACAACATCT ATGAAGTCAT   1620               GGTCTTGGCC ATGGACAATG GAAGCCCTCC CACCACTGGC ACGGGAACCC TTCTGCTAAC   1680               ACTGATTGAT GTCAATGACC ATGGCCCAGT CCCTGAGCCC CGTCAGATCA CCATCTGCAA   1740               CCAAAGCCCT GTGCGCCAGG TGCTGAACAT CACGGACAAG GACCTGTCTC CCCACACCTC   1800               CCCTTTCCAG GCCCAGCTCA CAGATGACTC AGACATCTAC TGGACGGCAG AGGTCAACGA   1860               GGAAGGTGAC ACAGTGGTCT TGTCCCTGAA GAAGTTCCTG AAGCAGGATA CATATGACGT   1920               GCACCTTTCT CTGTCTGACC ATGGCAACAA AGAGCAGCTG ACGGTGATCA GGGCCACTGT   1980               GTGCGACTGC CATGGCCATG TCGAAACCTG CCCTGGACCC TGGAAGGGAG GTTTCATCCT   2040               CCCTGTGCTG GGGGCTGTCC TGGCTCTGCT GTTCCTCCTG CTGGTGCTGC TTTTGTTGGT   2100               GAGAAAGAAG CGGAAGATCA AGGAGCCCCT CCTACTCCCA GAAGATGACA CCCGTGACAA   2160               CGTCTTCTAC TATGGCGAAG AGGGGGGTGG CGAAGAGGAC CAGGACTATG ACATCACCCA   2220               GCTCCACCGA GGTCTGGAGG CCAGGCCGGA GGTGGTTCTC CGCAATGACG TGGCACCAAC   2280               CATCATCCCG ACACCCATGT ACCGTCCTCG GCCAGCCAAC CCAGATGAAA TCGGCAACTT   2340               TATAATTGAG AACCTGAAGG CGGCTAACAC AGACCCCACA GCCCCGCCCT ACGACACCCT   2400               CTTGGTGTTC GACTATGAGG GCAGCGGCTC CGACGCCGCG TCCCTGAGCT CCCTCACCTC   2460               CTCCGCCTCC GACCAAGACC AAGATTACGA TTATCTGAAC GAGTGGGGCA GCCGCTTCAA   2520               GAAGCTGGCA GACATGTACG GTGGCGGGGA GGACGACTAG GCGGCCTGCC TGCAGGGCTG   2580               GGGACCAAAC GTCAGGCCAC AGAGCATCTC CAAGGGGTCT CAGTTCCCCC TTCAGCTGAG   2640               GACTTCGGAG CTTGTCAGGA AGTGGCCGTA GCAACTTGGC GGAGACAGGC TATGAGTCTG   2700               ACGTTAGAGT GGTTGCTTCC TTAGCCTTTC AGGATGGAGG AATGTGGGCA GTTTGACTTC   2760               AGCACTGAAA ACCTCTCCAC CTGGGCCAGG GTTGCCTCAG AGGCCAAGTT TCCAGAAGCC   2820               TCTTACCTGC CGTAAAATGC TCAACCCTGT GTCCTGGGCC TGGGCCTGCT GTGACTGACC   2880               TACAGTGGAC TTTCTCTCTG GAATGGAACC TTCTTAGGCC TCCTGGTGCA ACTTAATTTT   2940               TTTTTTTAAT GCTATCTTCA AAACGTTAGA GAAAGTTCTT CAAAAGTGCA GCCCAGAGCT   3000               GCTGGGCCCA CTGGCCGTCC TGCATTTCTG GTTTCCAGAC CCCAATGCCT CCCATTCGGA   3060               TGGATCTCTG CGTTTTTATA CTGAGTGTGC CTAGGTTGCC CCTTATTTTT TATTTTCCCT   3120               GTTGCGTTGC TATAGATGAA GGGTGAGGAC AATCGTGTAT ATGTACTAGA ACTTTTTTAT   3180               TAAAGAAACT TTTCCCAGAA AAAAA               Seq ID NO: 14 Protein sequence:       Protein Accession #: NP_001784.2               1   11   21   31   41   51       |  |   |    |   |   |       MGLPRGPLAS LLLLQVCWLQ CAASEPCRAV FREAEVTLEA GGAEQEPGQA LGKVFMGCPG   60               QEPALFSTDN DDFTVRNGET VQERRSLKER NPLKIFPSKR ILRRHKRDWV VAPISVPENG   120               KGPFPQRLNQ LKSNKDRDTK IFYSITGPGA DSPPEGVFAV EKETGWLLLN KPLDREEIAK   180               YELFGHAVSE NGASVEDPMN ISIIVTDQND HKPKFTQDTF RGSVLEGVLP GTSVMQVTAT   240               DEDDAIYTYN GVVAYSIHSQ EPKDPHDLMF TIHRSTGTIS VISSGLDREK VPEYTLTIQA   300               TDMDGDGSTT TAVAVVEILD ANDNAPMFDP QKYEAHVPEN AVGHEVQRLT VTDLDAPNSP   360               AWRATYLIMG GDDGDHFTIT THPESNQGIL TTRKGLDFEA KNQHTLYVEV TNEAPFVLKL   420               PTSTATIVVH VEDVNEAPVF VPPSKVVEVQ EGIPTGEPVC VYTAEDPDKE NQKISYRILR   480               DPAGWLAMDP DSGQVTAVGT LDREDEQFVR NNIYEVMVLA MDNGSPPTTG TGTLLLTLID   540               VNDHGPVPEP RQITICNQSP VRQVLNITDK DLSPHTSPFQ AQLTDDSDIY WTAEVNEEGD   600               TVVLSLKKFL KQDTYDVHLS LSDHGNKEQL TVIRATVCDC HGHVETCPGP WKGGFILPVL   660               GAVLALLFLL LVLLLLVRKK RKIKEPLLLP EDDTRDNVFY YGEEGGGEED QDYDITQLHR   720               GLEARPEVYL RNDVAPTIIP TPMYRPRPAN PDEIGNFIIE NLKAANTDPT APPYDTLLVF   780               DYEGSGSDAA SLSSLTSSAS DQDQDYDYLN EWGSRFKKLA DMYGGGEDD               Seq ID NO: 15 DNA sequence       Nucleic Acid Accession #: XM_051860.2       Coding sequence: 261-4346               1   11   21   31   41   51       |  |   |    |   |   |       GAGCTAGCGC TCAAGCAGAG CCCAGCGCGG TGCTATCGGA CAGAGCCTGG CGAGCGCAAG   60               CGGCGCGGGG AGCCAGCGGG GCTGAGCGCG GCCAGGGTCT GAACCCAGAT TTCCCAGACT   120               AGCTACCACT CCGCTTGCCC ACGCCCCGGG AGCTCGCGGC GCCTGGCGGT CAGCGACCAG   180               ACGTCCGGGG CCGCTGCGCT CCTGGCCCGC GAGGCGTGAC ACTGTCTCGG CTACAGACCC   240               AGAGGGAGCA CACTGCCAGG ATGGGAGCTG CTGGGAGGCA GGACTTCCTC TTCAAGGCCA   300               TGCTGACCAT CAGCTGGCTC ACTCTGACCT GCTTCCCTGG GGCCACATCC ACAGTGGCTG   360               CTGGGTGCCC TGACCAGAGC CCTGAGTTGC AACCCTGGAA CCCTGGCCAT GACCAAGACC   420               ACCATGTGCA TATCGGCCAG GGCAAGACAC TGCTGCTCAC CTCTTCTGCC ACGGTCTATT   480               CCATCCACAT CTCAGAGGGA GGCAAGCTGG TCATTAAAGA CCACGACGAG CCGATTGTTT   540               TGCGAACCCG GCACATCCTG ATTGACAACG GAGGAGAGCT GCATGCTGGG AGTGCCCTCT   600               GCCCTTTCCA GGGCAATTTC ACCATCATTT TGTATGGAAG GGCTGATGAA GGTATTCAGC   660               CGGATCCTTA CTATGGTCTG AAGTACATTG GGGTTGGTAA AGGAGGCGCT CTTGAGTTGC   720               ATGGACAGAA AAAGCTCTCC TGGACATTTC TGAACAAGAC CCTTCACCCA GGTGGCATGG   780               CAGAAGGAGG CTATTTTTTT GAAAGGAGCT GGGGCCACCG TGGAGTTATT GTTCATGTCA   840               TCGACCCCAA ATCAGGCACA GTCATCCATT CTGACCGGTT TGACACCTAT AGATCCAAGA   900               AAGAGAGTGA ACGTCTGGTC CAGTATTTGA ACGCGGTGCC CGATGGCAGG ATCCTTTCTG   960               TTGCAGTGAA TGATGAAGGT TCTCGAAATC TGGATGACAT GGCCAGGAAG GCGATGACCA   1020               AATTGGGAAG CAAACACTTC CTGCACCTTG GATTTAGACA CCCTTGGAGT TTTCTAACTG   1080               TGAAAGGAAA TCCATCATCT TCAGTGGAAG ACCATATTGA ATATCATGGA CATCGAGGCT   1140               CTGCTGCTGC CCGGGTATTC AAATTGTTCC AGACAGAGCA TGGCGAATAT TTCAATGTTT   1200               CTTTGTCCAG TGAGTGGGTT CAAGACGTGG AGTGGACGGA GTGGTTCGAT CATGATAAAG   1260               TATCTCAGAC TAAAGGTGGG GAGAAAATTT CAGACCTCTG GAAAGCTCAC CCAGGAAAAA   1320               TATGCAATCG TCCCATTGAT ATACAGGCCA CTACAATGGA TGGAGTTAAC CTCAGCACCG   1380               AGGTTGTCTA CAAAAAAGGC CAGGATTATA GGTTTGCTTG CTACGACCGG GGCAGAGCCT   1440               GCCGGAGCTA CCGTGTACGG TTCCTCTGTG GGAAGCCTGT GAGGCCCAAA CTCACAGTCA   1500               CCATTGACAC CAATGTGAAC AGCACCATTC TGAACTTGGA GGATAATGTA CAGTCATGGA   1560               AACCTGGAGA TACCCTGGTC ATTGCCAGTA CTGATTACTC CATGTACCAG GCAGAAGAGT   1620               TCCAGGTGCT TCCCTGCAGA TCCTGCGCCC CCAACCAGGT CAAAGTGGCA GGGAAACCAA   1680               TGTACCTGCA CATCGGGGAG GAGATAGACG GCGTGGACAT GCGGGCGGAG GTTGGGCTTC   1740               TGAGCCGGAA CATCATAGTG ATGGGGGAGA TGGAGGACAA ATGCTACCCC TACAGAAACC   1800               ACATCTGCAA TTTCTTTGAC TTCGATACCT TTGGGGGCCA CATCAAGTTT GCTCTGGGAT   1860               TTAAGGCAGC ACACTTGGAG GGCACGGAGC TGAAGCATAT GGGACAGCAG CTGGTGGGTC   1920               AGTACCCGAT TCACTTCCAC CTGGCCGGTG ATGTAGACGA AAGGGGAGGT TATGACCCAC   1980               CCACATACAT CAGGGACCTC TCCATCCATC ATACATTCTC TCGCTGCGTC ACAGTCCATG   2040               GCTCCAATGG CTTGTTGATC AAGGACGTTG TGGGCTATAA CTCTTTGGGC CACTGCTTCT   2100               TCACGGAAGA TGGGCCGGAG GAACGCAACA CTTTTGACCA CTGTCTTGGC CTCCTTGTCA   2160               AGTCTGGAAC CCTCCTCCCC TCGGACCGTG ACAGCAAGAT GTGCAAGATG ATCACAGAGG   2220               ACTCCTACCC GGGGTACATC CCCAAGCCCA GGCAAGACTG CAATGCTGTG TCCACCTTCT   2280               GGATGGCCAA TCCCAACAAC AACCTCATCA ACTGTGCCGC TGCAGGATCT GAGGAAACTG   2340               GATTTTGGTT TATTTTTCAC CACGTACCAA CGGGCCCCTC CGTGGGAATG TACTCCCCAG   2400               GTTATTCAGA GCACATTCCA CTGGGAAAAT TCTATAACAA CCGAGCACAT TCCAACTACC   2460               GGGCTGGCAT GATCATAGAC AACGGAGTCA AAACCACCGA GGCCTCTGCC AAGGACAAGC   2520               GGCCGTTCCT CTCAATCATC TCTGCCAGAT ACAGCCCTCA CCAGGACGCC GACCCGCTGA   2580               AGCCCCGGGA GCCGGCCATC ATCAGACACT TCATTGCCTA CAAGAACCAG GACCACGGGG   2640               CCTGGCTGCG CGGCGGGGAT GTGTGGCTGG ACAGCTGCCG GTTTGCTGAC AATGGCATTG   2700               GCCTGACCCT GGCCAGTGGT GGAACCTTCC CGTATGACGA CGGCTCCAAG CAAGAGATAA   2760               AGAACAGCTT GTTTGTTGGC GAGAGTGGCA ACGTGGGGAC GGAAATGATG GACAATAGGA   2820               TCTGGGGCCC TGGCGGCTTG GACCATAGCG GAAGGACCCT CCCTATAGGC CAGAATTTTC   2880               CAATTAGAGG AATTCAGTTA TATGATGGCC CCATCAACAT CCAAAACTGC ACTTTCCGAA   2940               AGTTTGTGGC CCTGGAGGGC CGGCACACCA GCGCCCTGGC CTTCCGCCTG AATAATGCCT   3000               GGCAGAGCTG CCCCCATAAC AACGTGACCG GCATTGCCTT TGAGGACGTT CCGATTACTT   3060               CCAGAGTGTT CTTCGGAGAG CCTGGGCCCT GGTTCAACCA GCTGGACATG GATGGGGATA   3120               AGACATCTGT GYTCCATGAC GTCGACGGCT CCGTGTCCGA GTACCCTGGC TCCTACCTCA   3180               CGAAGAATGA CAACTGGCTG GTCCGGCACC CAGACTGCAT CAATGTTCCC GACTGGAGAG   3240               GGGCCATTTG CAGTGGGTGC TATGCACAGA TGTACATTCA AGCCTACAAG ACCAGTAACC   3300               TGCGAATGAA GATCATCAAG AATGACTTCC CCAGCCACCC TCTTTACCTG GAGGGGGCGC   3360               TCACCAGGAG CACCCATTAC CAGCAATACC AACCGGTTGT CACCCTGCAG AAGGGCTACA   3420               CCATCCACTG GGACCAGACG GCCCCCGCCG AACTCGCCAT CTGGCTCATC AACTTCAACA   3480               AGGGCGACTG GATCCGAGTG GGGCTCTGCT ACCCGCGAGG CACCACATTC TCCATCCTCT   3540               CGGATGTTCA CAATCGCCTG CTGAAGCAAA CGTCCAAGAC GGGCGTCTTC GTGAGGACCT   3600               TGCAGATGGA CAAAGTGGAG CAGAGCTACC CTGGCAGGAG CCACTACTAC TGGGACGAGG   3660               ACTCAGGGCT GTTGTTCCTG AAGCTGAAAG CTCAGAACGA GAGAGAGAAG TTTGCTTTCT   3720               GCTCCATGAA AGGCTGTGAG AGGATAAAGA TTAAAGCTCT GATTCCAAAG AACGCAGGCG   3780               TCAGTGACTG CACAGCCACA GCTTACCCCA AGTTCACCGA GAGGGCTGTC GTAGACGTGC   3840               CGATGCCCAA GAAGCTCTTT GGTTCTCAGC TGAAAACAAA GGACCATTTC TTGGAGGTGA   3900               AGATGGAGAG TTCCAAGCAG CACTTCTTCC ACCTCTGGAA CGACTTCGCT TACATTGAAG   3960               TGGATGGGAA GAAGTACCCC AGTTCGGAGG ATGGCATCCA GGTGGTGGTG ATTGACGGGA   4020               ACCAAGGGCG CGTGGTGAGC CACACGAGCT TCAGGAACTC CATTCTGCAA GGCATACCAT   4080               GGCAGCTTTT CAACTATGTG GCGACCATCC CTGACAATTC CATAGTGCTT ATGGCATCAA   4140               AGGGAAGATA CGTCTCCAGA GGCCCATGGA CCAGAGTGCT GGAAAAGCTT GGGGCAGACA   4200               GGGGTCTCAA GTTGAAAGAG CAAATGGCAT TCGTTGGCTT CAAAGGCAGC TTCCGGCCCA   4260               TCTGGGTGAC ACTGGACACT GAGGATCACA AAGCCAAAAT CTTCCAAGTT GTGCCCATCC   4320               CTGTGGTGAA GAAGAAGAAG TTGTGAGGAC AGCTGCCGCC CGGTGCCACC TCGTGGTAGA   4380               CTATGACGGT GACTCTTGGC AGCAGACCAG TGGGGGATGG CTGGGTCCCC CAGCCCCTGC   4440               CAGCAGCTGC CTGGGAAGGC CGTGTTTCAG CCCTGATGGG CCAAGGGAAG GCTATCAGAG   4500               ACCCTGGTGC TGCCACCTGC CCCTACTCAA GTGTCTACCT GGAGCCCCTG GGGCGGTGCT   4560               GGCCAATGCT GGAAACATTC ACTTTCCTGC AGCCTCTTGG GTGCTTCTCT CCTATCTGTG   4620               CCTCTTCAGT GGGGGTTTGG GGACCATATC AGGAGACCTG GGTTGTGCTG ACAGCAAAGA   4680               TCCACTTTGG CAGGAGCCCT GACCCAGCTA GGAGGTAGTC TGGAGGGCTG GTCATTCACA   4740               GATCCCCATG GTCTTCAGCA GACAAGTGAG GGTGGTAAAT GTAGGAGAAA GAGCCTTGGC   4800               CTTAAGGAAA TCTTTACTCC TGTAAGCAAG AGCCAACCTC ACAGGATTAG GAGCTGGGGT   4860               AGAACTGGCT ATCCTTGGGG AAGAGGCAAG CCCTGCCTCT GGCCGTGTCC ACCTTTCAGG   4920               AGACTTTGAG TGGCAGGTTT GGACTTGGAC TAGATGACTC TCAAAGGCCC TTTTAGTTCT   4980               GAGATTCCAG AAATCTGCTG CATTTCACAT GGTACCTGGA ACCCAACAGT TCATGGATAT   5040               CCACTGATAT CCATGATGCT GGGTGCCCCA GCGCACACGG GATGGAGAGG TGAGAACTAA   5100               TGCCTAGCTT GAGGGGTCTG CAGTCCAGTA GGGCAGGCAG TCAGGTCCAT GTGCACTGCA   5160               ATGCCAGGTG GAGAAATCAC AGAGAGGTAA AATGGAGGCC AGTGCCATTT CAGAGGGGAG   5220               GCTCAGGAAG GCTTCTTGCT TACAGGAATG AAGGCTGGGG GCATTTTGCT GGGGGGAGAT   5280               GAGGCAGCCT CTGGAATGGC TCAGGGATTC AGCCCTCCCT GCCGCTGCCT GCTGAAGCTG   5340               GTGACTACGG GGTCGCCCTT TGCTCACGTC TCTCTGGCCC ACTCATGATG GAGAAGTGTG   5400               GTCAGAGGGG AGCAATGGGC TTTGCTGCTT ATGAGCACAG AGGAATTCAG TCCCCAGGCA   5460               GCCCTGCCTC TGACTCCAAG AGGGTGAAGT CCACAGAAGT GAGCTCCTGC CTTAGGGCCT   5520               CATTTGCTCT TCATCCAGGG AACTGAGCAC AGGGGGCCTC CAGGAGACCC TAGATGTGCT   5580               CGTACTCCCT CGGCCTGGGA TTTCAGAGCT GGAAATATAG AAAATATCTA GCCCAAAGCC   5640               TTCATTTTAA CAGATGGGGA AAGTGAGCCC CCAAGATGGG AAAGAACCAC ACAGCTAAGG   5700               GAGGGCCTGG GGAGCCCCAC CCTAGCCCTT GCTGCCACAC CACATTGCCT CAACAACCGG   5760               CCCCAGAGTG CCCAGGCACT CCTGAGGTAG CTTCTGGAAA TGGGGACAAG TCCCCTCGAA   5820               GGAAAGGAAA TGACTAGAGT AGAATGACAG CTAGCAGATC TCTTCCCTCC TGCTCCCAGC   5880               GCACACAAAC CCGCCCTCCC CTTGGTGTTG GCGGTCCCTG TGGCCTTCAC TTTGTTCACT   5940               ACCTGTCAGC CCAGCCTGGG TGCACAGTAG CTGCAACTCC CCATTGGTGC TACCTGGCTC   6000               TCCTGTCTCT GCAGCTCTAC AGGTGAGGCC CAGCAGAGGG AGTAGGGCTC GCCATGTTTC   6060               TGGTGAGCCA ATTTGGCTGA TCTTGGGTGT CTGAACAGCT ATTGGGTCCA CCCCAGTCCC   6120               TTTCAGCTGC TGCTTAATGC CCTGCTCTCT CCCTGGCCCA CCTTATAGAG AGCCCAAAGA   6180               GCTCCTGTAA GAGGGAGAAC TCTATCTGTG GTTTATAATC TTGCACGAGG CACCAGAGTC   6240               TCCCTGGGTC TTGTGATGAA CTACATTTAT CCCCTTTCCT GCCCCAACCA CAAACTCTTT   6300               CCTTCAAAGA GGGCCTGCCT GGCTCCCTCC ACCCAACTGC ACCCATGAGA CTCGGTCCAA   6360               GAGTCCATTC CCCAGGTGGG AGCCAACTGT CAGGGAGGTC TTTCCCACCA AACATCTTTC   6420               AGCTGCTGGG AGGTGACCAT AGGGCTCTGC TTTTAAAGAT ATGGCTGCTT CAAAGGCCAG   6480               AGTCACAGGA AGGACTTCTT CCAGGGAGAT TAGTGGTGAT GGAGAGGAGA GTTAAAATGA   6540               CCTCATGTCC TTCTTGTCCA CGGTTTTGTT GAGTTTTCAC TCTTCTAATG CAAGGGTCTC   6600               ACACTGTGAA CCACTTAGGA TGTGATCACT TTCAGGTGGC CAGGAATGTT GAATGTCTTT   6660               GGCTCAGTTC ATTTAAAAAA GATATCTATT TGAAAGTTCT CAGAGTTGTA CATATGTTTC   6720               ACAGTACAGG ATCTGTACAT AAAAGTTTCT TTCCTAAACC ATTCACCAAG AGCCAATATC   6780               TAGGCATTTT CTTGGTAGCA CAAATTTTCT TATTGCTTAG AAAATTGTCC TCCTTGTTAT   6840               TTCTGTTTGT AAGACTTAAG TGAGTTAGGT CTTTAAGGAA AGCAACGCTC CTCTGAAATG   6900               CTTGTCTTTT TTCTGTTGCC GAAATAGCTG GTCCTTTTTC GGGAGTTAGA TGTATAGAGT   6960               GTTTGTATGT AAACATTTCT TGTAGGCATC ACCATGAACA AAGATATATT TTCTATTTAT   7020               TTATTATATG TGCACTTCAA GAAGTCACTG TCAGAGAAAT AAAGAATTGT CTTAAATGTC               Seq ID NO: 16 Protein sequence:       Protein Accession #: XP_051860.2               1   11   21   31   41   51       |  |   |    |   |   |       MGAAGRQDFL FKAMLTISWL TLTCFPGATS TVAAGCPDQS PELQPWNPGH DQDHHVHIGQ   60               GKTLLLTSSA TVYSIHISEG GKLVIKDHDE PIVLRTRHIL IDNGGELHAG SALCPFQGNF   120               TIILYGRADE GIQPDPYYGL KYIGVGKGGA LELHGQKKLS WTFLNKTLHP GGMAEGGYFF   180               ERSWGHRGVI VHVIDPKSGT VIHSDRFDTY RSKKESERLV QYLNAVPDGR ILSVAVNDEG   240               SRNLDDMARK AMTKLGSKHF LHLGFRHPWS FLTVKGNPSS SVEDHIEYHG HRGSAAARVF   300               KLFQTEHGEY FNVSLSSEWV QDVEWTEWFD HDKVSQTKGG EKISDLWKAH PGKICNRPID   360               IQATTMDGVN LSTEVVYKKG QDYRFACYDR GRACRSYRVR FLCGKPVRPK LTVTIDTNVN   420               STILNLEDNV QSWKPGDTLV IASTDYSMYQ AEEFQVLPCR SCAPNQVKVA GKPMYLHIGE   480               EIDGVDMRAE VGLLSRNIIV MGEMEDKCYP YRNHICNFFD FDTFGGHIKF ALGFKAAHLE   540               GTELKHMGQQ LVGQYPIHFH LAGDVDERGG YDPPTYIRDL SIHHTFSRCV TVHGSNGLLI   600               KDVVGYNSLG HCFFTEDGPE ERNTFDHCLG LLVKSGTLLP SDRDSKMCKM ITEDSYPGYI   660               PKPRQDCNAV STFWMANPNN NLINCAAAGS EETGFWFIFH HVPTGPSVGM YSPGYSEHIP   720               LGKFYNNRAH SNYRAGMIID NGVKTTEASA KDKRPFLSII SARYSPHQDA DPLKPREPAI   780               IRHFIAYKNQ DHGAWLRGGD VWLDSCRFAD NGIGLTLASG GTFPYDDGSK QEIKNSLFVG   840               ESGNVGTEMM DNRIWGPGGL DHSGRTLPIG QNFPIRGIQL YDGPINIQNC TFRKFVALEG   900               RHTSALAFRL NNAWQSCPHN NVTGIAFEDV PITSRVFFGE PGPWFNQLDM DGDKTSVFHD   960               VDGSVSEYPG SYLTKNDNWL VRHPDCINVP DWRGAICSGC YAQMYIQAYK TSNLRMKIIK   1020               NDFPSHPLYL EGALTRSTHY QQYQPVVTLQ KGYTIHWDQT APAELAIWLI NFNKGDWIRV   1080               GLCYPRGTTF SILSDVHNRL LKQTSKTGVF VRTLQMDKVE QSYPGRSHYY WDEDSGLLFL   1140               KLKAQNEREK FAFCSMKGCE RIKIKALIPK NAGVSDCTAT AYPKFTERAV VDVPMPKKLF   1200               GSQLKTKDHF LEVKMESSKQ HFFHLWNDFA YIEVDGKKYP SSEDGIQVVV IDGNQGRVVS   1260               HTSFRNSILQ GIPWQLFNYV ATIPDNSIVL MASKGRYVSR GPWTRVLEKL GADRGLKLKE   1320               QMAFVGFKGS FRPIWVTLDT EDHKAKIFQV VPIPVVKKKK L               Seq ID NO: 17 DNA sequence       Nucleic Acid Accession #: NM_015515.1       Coding sequence: 61-1329               1   11   21   31   41   51       |  |   |    |   |   |       AGTTCTGCGG TGCCAGGGAG TGGAGCAGAG CTCAGCCCCG TCCCAAACAC AGATGGGACC   60               ATGAACTCCG GACACAGCTT CAGCCAGACC CCCTCGGCCT CCTTCCATGG CGCCGGAGGT   120               GGCTGGGGCC GGCCCAGGAG CTTCCCCAGG GCTCCCACCG TCCATGGCGG TGCGGGGGGA   180               GCCCGCATCT CCCTGTCCTT CACCACGCGG AGCTGCCCAC CCCCTGGAGG GTCTTGGGGT   240               TCTGGAAGAA GCAGCCCCCT ACTAGGCGGA AATGGGAAGG CCACCATGCA GAATCTCAAC   300               GACCGCCTGG CCTCCTACCT GGAGAAGGTT CGCGCCCTGG AGGAGGCCAA CATGAAGCTG   360               GAAAGCCGCA TCCTGAAATG GCACCAGGAG AGAGATCCTG GCAGTAAGAA AGATTATTCC   420               CAGTATGAGG AAAACATCAC ACACCTGCAG GAGCAGATAG TGGATGGTAA GATGACCAAT   480               GCTCAGATTA TTCTTCTCAT TGACAATGCC AGGATGGCAG TGGATGACTT CAACCTCAAG   540               TATGAAAATG AACACTCCTT TAAGAAAGAC TTGGAAATTG AAGTCGAGGG CCTCCGAAGG   600               ACCTTAGACA ACCTGACCAT TGTCACAACA GACCTAGAAC AGGAGGTGGA AGGAATGAGG   660               AAAGAGCTCA TTCTCATGAA GGAGCACCAT GAGCAGGAAA TGGAGGAGCA TCATGTGCCA   720               AGTGACTTCA ATGTCAATGT GAAGGTGGAT ACAGGTCCCA GGGAAGATCT GATTAAGGTC   780               CTGGAGGATA TGAGACAAGA ATATGAGCTT ATAATAAAGA AGAAGCATCG AGACTTGGAC   840               ACTTGGTATA AAGAACAGTC TGCAGCCATG TCCCAGGAGG CAGCCAGTCC AGCCACTGTG   900               CAGAGCAGAC AAGGTGACAT CCACGAACTG AAGCGCACAT TCCAGGCCCT GGAGATTGAC   960               CTGCAGGCAC AGTACAGCAC GAAATCTGCT TTGGAAAACA TGTTATCCGA GACCCAGTCT   1020               CGGTACTCCT GCAAGCTCCA GGACATGCAA GAGATCATCT CCCACTATGA GGAGGAACTG   1080               ACGCAGCTAC GCCACGAACT GGAGCGGCAG AACAATGAAT ACCAAGTGCT GCTGGGCATC   1140               AAAACCCACC TGGAGAAGGA AATCACCACG TACCGACGGC TCCTGGAGGG AGAGAGTGAA   1200               GGGACACGGG AAGAATCAAA GTCGAGCATG AAAGTGTCTG CAACTCCAAA GATCAAGGCC   1260               ATAACCCAGG AGACCATCAA CGGAAGATTA GTTCTTTGTC AAGTGAATGA AATCCAAAAG   1320               CACGCATGAG ACCAATGAAA GTTTCCGCCT GTTGTAAAGT CTATTTTCCC CCAAGGAAAG   1380               TCCTTGCACA GACACCAGTG AGTGAGTTCT AAAAGATACC CTTGGAATTA TCAGACTCAG   1440               AAACTTTTAT TTTTTTTTTT CTGTAACAGT CTCACCAGAC TTCTCATAAT GCTCTTAATA   1500               TATTGCACTT TTCTAATCAA AGTGCGAGTT TATGAGGGTA AAGCTCTACT TTCCTACTGC   1560               AGCCTTCAGA TTCTCATCAT TTTGCATCTA TTTTGTAGCC AATAAAACTC CGCACTAGC                   Seq ID NO: 18 Protein sequence:       Protein Accession #: NP_056330.1               1   11   21   31   41   51       |  |   |    |   |   |       MNSGHSFSQT PSASFHGAGG GWGRPRSFPR APTVHGGAGG ARISLSFTTR SCPPPGGSWG   60               SGRSSPLLGG NGKATMQNLN DRLASYLEKV RALEEANMKL ESRILKWHQQ RDPGSKKDYS   120               QYEENITHLQ EQIVDGKMTN AQIILLIDNA RMAVDDFNLK YENEHSFKKD LEIEVEGLRR   180               TLDNLTIVTT DLEQEVEGMR KELILMKEHH EQEMEEHHVP SDFNVNVKVD TGPREDLIKV   240               LEDMRQEYEL IIKKKHRDLD TWYKEQSAAM SQEAASPATV QSRQGDIHEL KRTFQALEID   300               LQAQYSTKSA LENMLSETQS RYSCKLQDMQ EIISHYEEEL TQLRHELERQ NNEYQVLLGI   360               KTHLEKEITT YRRLLEGESE GTREESKSSM KVSATPKIKA ITQETINGRL VLCQVNEIQK   420               HA               Seq ID NO: 19 DNA sequence       Nucleic Acid Accession #: see Table 25 &amp; 25A for complete list               1   11   21   31   41   51       |  |   |    |   |   |       TTTTTTTTTT TTAAAAAAAA GAGGCTTGGT AAGTTTTTGA TACTTAGTTG ACTTTTAGCA   60               TTATCCAGCA TTFGTATTAT GAACCAGTGA GTACTGTAAT TTTTCTTTCC CTTTCAGAAA   120               GACTCAAAGG GAACATATAA ATGTTTCCTA TTTTTNNNNN NNNNNNNNNN NNNNNNNNNN   180               NNNNACCCAT CGTGCGATGA TCNNNNNNNN NNNNNNNNNN NNNNNTTGGG ATCCAGTTTC   240               AAATAAGGTA TGGGAAAAAC AGATGTTTTC ATTATCGCCA CTTAATCCTT ACTTCCGATT   300               ATAATTATAC ATGTTTGGCT GTAATAACTA TACTAAAGCA TGCTTGTGAA AGTAGACTTC   360               TACAAGGACA GAAAACCCAC AACAACAAAG ATCGATCACG AAAGACAAGG CATATTCATT   420               CATTAATTTA CTTCTCTTAG ACCCGGGACA TGTGGGACAA ATACTTTTGT CCTCATGGAT   480               GGCTTGATAA TTTATTTATA TGTTCTAGAG TCTGAGGATT TTCTTTCAGT GGCAGACAAC   540               AAAGGATGTT ACAATTTACT TCAAAATAAT ACAATCATGG TTTAATTTAC AGTGTAAATC   600               CATAACTATT TTATAGAGAT GGATTATCAT ACATGGGATT ATAAAAATAA CTTACCCATA   660               TGCTTGCAAA ATAGACTTTT CCTATTGGGA GGAACATCTT TTAACCTAAA ACGGATTTAT   720               TTCAGATGAA TTAGACAGTA CATTTTTCAG GAGAACCAGC CTTACTGGAT GATCTTTTGT   780               CAGGTTTGGA GGCCTCTTCT TTGTCTTTGC AACCATAACC CCTTTTCAGC TGAAGACCAC   840               TGGCCTTCAA CCCAAGCCAG GAGTTTGGCT CAAATGA               Seq ID NO: 20 DNA sequence       Nucleic Acid Accession #: D3205 1.1       Coding sequence: 72-1373               1   11   21   31   41   51       |  |   |    |   |   |       GAATTCGAAC CAGGTGGCCA CCCGGTGTCG GTTTCATTTT CCTTTGGAAT TTCTGCTTTA   60               CAGACAGAAC AATGGCAGCC CGAGTACTTA TAATTGGCAG TGGAGGAAGG GAACATACGC   120               TGGCCTGGAA ACTTGCACAG TCTCATCATG TCAAACAAGT GTTGGTTGCC CCAGGAAACG   180               CAGGCACTGC CTGCTCTGAA AAGATTTCAA ATACCGCCAT CTCAATCAGT GACCACACTG   240               CCCTTGCTCA ATTCTGCAAA GAGAAGAAAA TTGAATTTGT AGTTGTTGGA CCAGAAGCAC   300               CTCTGGCTGC TGGGATTGTT GGGAACCTGA GGTCTGCAGG AGTGCAATGC TTTGGCCCAA   360               CAGCAGAAGC GGCTCAGTTA GAGTCCAGCA AAAGGTTTGC CAAAGAGTTT ATGGACAGAC   420               ATGGAATCCC AACCGCACAA TGGAAGGCTT TCACCAAACC TGAAGAAGCC TGCAGCTTCA   480               TTTTGAGTGC AGACTTCCCT GCTTTGGTTG TGAAGGCCAG TGGTCTTGCA GCTGGAAAAG   540               GGGTGATTGT TGCAAAGAGC AAAGAAGAGG CCTGCAAAGC TGTACAAGAG ATCATGCAGG   600               AGAAAGCCTT TGGGGCAGCT GGAGAAACAA TTGTCATTGA AGAACTTCTT GACGGAGAAG   660               AGGTGTCGTG TCTGTGTTTC ACTGATGGCA AGACTGTGGC CCCCATGCCC CCAGCACAGG   720               ACCATAAGCG ATTACTGGAG GGAGATGGTG GCCCTAACAC AGGGGGAATG GGAGCCTATT   780               GTCCAGCCCC TCAGGTTTCT AATGATCTAT TACTAAAAAT TAAAGATACT GTTCTTCAGA   840               GGACAGTGGA TGGCATGCAG CAAGAGGGTA CTCCATATAC AGGTATTCTC TATGCTGGAA   900               TAATGCTGAC CAAGAATGGC CCAAAAGTTC TAGAGTTTAA TFGCCGTTTT GGTGATCCAG   960               AGTGCCAAGT AATCCTCCCA CTTCTTAAAA GTGATCTTTA TGAAGTGATT CAGTCCACCT   1020               TAGATGGACT GCTCTGCACA TCTCTGCCTG TTTGGCTAGA AAACCACACC GCCCTAACTG   1080               TTGTCATGGC AAGTAAAGGT TATCCTGGAG ACTACACCAA GGGTGTAGAG ATAACAGGGT   1140               TTCCTGAGGC TCAAGCTCTA GGACTGGAGG TGTCCCATGC AGGCACTGCC CTCAAAAATG   1200               GCAAAGTAGT AACTCATGGG GGTAGAGTTC TTGCAGTCAC AGCCATCCGG GAAAATCTCA   1260               TATCAGCCCT TGAGGAAGCC AAGAAAGGAC TAGCTGCTAT AAAGTTTGAG GGAGCAATTT   1320               ATAGGAAAGA CATCGGCTTT CGTGCCATAG CTTTCCTCCA GCAGCCCAGG TAAAACTCTA   1380               AGCAAGTTAG CTGTAGTGCC ATTTCAGAAA CTGGCCTAAA TGGCTATGTA GAACATTCCA   1440               TTAACCCTAT AAGTCATTCA GTATTCTTTT CTCTCTGTGG GAGTGATACA GTCTTGGTTT   1500               GTATTTTGTT TGAATCAAAA CTGGTTATAG CAATACTCAA ATGGAAAAAA CTTCATGATA   1560               GCGTAAGTTT GGAAAGTTTA GCAAAATCAC AGTGGTACTG ATTTTTATTT GTTTTCTATT   1620               TTTTTTATTT TATATTTTTA ATTTTTTTAA CAGGGTCTTC CTCTCTCGCC CAAGTTCTCA   1680               TGCCTCAGCC TCCCAAATAG CTGGGACTAC AGGCACAGGC CACCACACCT GGCTAATTTT   1740               TTTGTATTTT TTGTGGAGAT GGGGTTCACC ATGTTGCCAA GGCCAGTCTG AAAGCCTGGG   1800               CTCAAGTGAT CCTCCTGCTT TGGCCTCCCA AAATGCTGGG ACTATAGGCA TGAGGCGCTG   1860               CACTTGGCCT GATACTGATT TTTATTCCTT GCGTTATCAC ATAGTGTTGT ATTTGAAACA   1920               TAGTTCATGG TTTTATCAAA GAACTGAAGA TGAGAATACT GGTCATCTAA CTTTGTAATT   1980               TGATTTGATT ATACTGTAAA GTTTGACAGT CCCATTTTAA CCTGCGTTTG TATCTATTAC   2040               TAAAATGTAT TTTTTGACCT CTTACTGATT CATGGTTGGT ATGTACAAAC TGTTGACTTG   2100               TAAAATCAAT AAAGTCTTAG TTGG               Seq ID NO: 21 Protein sequence:       Protein Accession #: BA.A06809.1               1   11   21   31   41   51       |  |   |    |   |   |       MAARVLIIGS GGREHTLAWK LAQSHHVKQV LVAPGNAGTA CSEKISNTAI SISDHTALAQ   60               FCKEKKIEFV VVGPEAPLAA GIVGNLRSAG VQCFGPTAEA AQLESSKRFA KEFMDRHGIP   120               TAQWKAFTKP EEACSFILSA DFPALVVKAS GLAAGKGVIV AKSKEEACKA VQEIMQEKAF   180               GAAGETIVIE ELLDGEEVSC LCFTDGKTVA PMPPAQDHKR LLEGDGGPNT GGMGAYCPAP   240               QVSNDLLLKI KDTVLQRTVD GMQQEGTPYT GILYAGIMLT KNGPKVLEFN CRFGDPECQV   300               ILPLLKSDLY EVIQSTLDGL LCTSLPVWLE NHTALTVVMA SKGYPGDYTK GVEITGFPEA   360               QALGLEVSHA GTALKNGKVV THGGRVLAVT AIRENLISAL EEAKKGLAAI KFEGAIYRKD   420               IGFRAIAFLQ QPR               Seq ID NO: 22 DNA sequence       Nucleic Acid Accession #: EOS cloned       Coding sequence: 1-2424               1   11   21   31   41   51       |  |   |    |   |   |       ATGCCCCCTT TCCTGTTGCT GGAGGCCGTC TGTGTTTTCC TGTTTTCCAG AGTGCCCCCA   60               TCTCTCCCTC TCCAGGAAGT CCATGTAAGC AAAGAAACCA TCGGGAAGAT TTCAGCTGCC   120               AGCAAAATGA TGTGGTGCTC GGCTGCAGTG GACATCATGT TTCTGTTAGA TGGGTCTAAC   180               AGCGTCGGGA AAGGGAGCTT TGAAAGGTCC AAGCACTTTG CCATCACAGT CTGTGACGGT   240               CTGGACATCA GCCCCGAGAG GGTCAGAGTG GGAGCATTCC AGTTCAGTTC CACTCCTCAT   300               CTGGAATTCC CCTTGGATTC ATTTTCAACC CAACAGGAAG TGAAGGCAAG AATCAAGAGG   360               ATGGTTTTCA AAGGAGGGCG CACGGAGACG GAACTTGCTC TGAAATACCT TCTGCACAGA   420               GGGTTGCCTG GAGGCAGAAA TGCTTCTGTG CCCCAGATCC TCATCATCGT CACTGATGGG   480               AAGTCCCAGG GGGATGTGGC ACTGCCATCC AAGCAGCTGA AGGAAAGGGG TGTCACTGTG   540               TTTGCTGTGG GGGTCAGGTT TCCCAGGTGG GAGGAGCTGC ATGCACTGGC CAGCGAGCCT   600               AGAGGGCAGC ACGTGCTGTT GGCTGAGCAG GTGGAGGATG CCACCAACGG CCTCTTCAGC   660               ACCCTCAGCA GCTCGGCCAT CTGCTCCAGC GCCACGCCAG ACTGCAGGGT CGAGGCTCAC   720               CCCTGTGAGC ACAGGACGCT GGAGATGGTC CGGGAGTTCG CTGGCAATGC CCCATGCTGG   780               AGAGGATCGC GGCGGACCCT TGCGGTGCTG GCTGCACACT GTCCCTTCTA CAGCTGGAAG   840               AGAGTGTTCC TAACCCACCC TGCCACCTGC TACAGGACCA CCTGCCCAGG CCCCTGTGAC   900               TCGCAGCCCT GCCAGAATGG AGGCACATGT GTTCCAGAAG GACTGGACGG CTACCAGTGC   960               CTCTGCCCGC TGGCCTTTGG AGGGGAGGCT AACTGTGCCC TGAAGCTGAG CCTGGAATGC   1020               AGGGTCGACC TCCTCTTCCT GCTGGACAGC TCTGCGGGCA CCACTCTGGA CGGCTTCCTG   1080               CGGGCCAAAG TCTTCGTGAA GCGGTTTGTG CGGGCCGTGC TGAGCGAGGA CTCTCGGGCC   1140               CGAGTGGGTG TGGCCACATA CAGCAGGGAG CTGCTGGTGG CGGTGCCTGT GGGGGAGTAC   1200               CAGGATGTGC CTGACCTGGT CTGGAGCCTC GATGGCATTC CCTTCCGTGG TGGCCCCACC   1260               CTGACGGGCA GTGCCTTGCG GCAGGCGGCA GAGCGTGGCT TCGGGAGCGC CACCAGGACA   1320               GGCCAGGACC GGCCACGTAG AGTGGTGGTT TTGCTCACTG AGTCACACTC CGAGGATGAG   1380               GTTGCGGGCC CAGCGCGTCA CGCAAGGGCG CGAGAGCTGC TCCTGCTGGG TGTAGGCAGT   1440               GAGGCCGTGC GGGCAGAGCT GGAGGAGATC ACAGGCAGCC CAAAGCATGT GATGGTCTAC   1500               TCGGATCCTC AGGATCTGTT CAACCAAATC CCTGAGCTGC AGGGGAAGCT GTGCAGCCGG   1560               CAGCGGCCAG GGTGCCGGAC ACAAGCCCTG GACCTCGTCT TCATGTTGGA CACCTCTGCC   1620               TCAGTAGGGC CCGAGAATTT TGCTCAGATG CAGAGCTTTG TGAGAAGCTG TGCCCTCCAG   1680               TTTGAGGTGA ACCCTGACGT GACACAGGTC GGCCTGGTGG TGTATGGCAG CCAGGTGCAG   1740               ACTGCCTTCG GGCTGGACAC CAAACCCACC CGGGCTGCGA TGCTGCGGGC CATTAGCCAG   1800               GCCCCCTACC TAGGTGGGGT GGGCTCAGCC GGCACCGCCC TGCTGCACAT CTATGACAAA   1860               GTGATGACCG TCCAGAGGGG TGCCCGGCCT GGTGTCCCCA AAGCTGTGGT GGTGCTCACA   1920               GGCGGGAGAG GCGCAGAGGA TGCAGCCGTT CCTGCCCAGA AGCTGAGGAA CAATGGCATC   1980               TCTGTCTTGG TCGTGGGCGT GGGGCCTGTC CTAAGTGAGG GTCTGCGGAG GCTTGCAGGT   2040               CCCCGGGATT CCCTGATCCA CGTGGCAGCT TACGCCGACC TGCGGTACCA CCAGGACGTG   2100               CTCATTGAGT GGCTGTGTGG AGAAGCCAAG CAGCCAGTCA ACCTCTGCAA ACCCAGCCCG   2160               TGCATGAATG AGGGCAGCTG CGTCCTGCAG AATGGGAGCT ACCGCTGCAA GTGTCGGGAT   2220               GGCTGGGAGG GCCCCCACTG CGAGAACCGT GAGTGGAGCT CTTGCTCTGT ATGTGTGAGC   2280               CAGGGATGGA TTCTTGAGAC GCCCCTGAGG CACATGGCTC CCGTGCAGGA GGGCAGCAGC   2340               CGTACCCCTC CCAGCAACTA CAGAGAAGGC CTGGGCACTG AAATGGTGCC TACCTTCTGG   2400               AATGTCTGTG CCCCAGGTCC TTAG               Seq ID NO: 23 Protein sequence:       Protein Accession #: EOS cloned               1   11   21   31   41   51       |  |   |    |   |   |       MPPFLLLEAV CVFLFSRVPP SLPLQEVHVS KETIGKISAA SKMMWCSAAV DIMFLLDGSN   60               SVGKGSFERS KHFAITVCDG LDISPERVRV GAFQFSSTPH LEFPLDSFST QQEVKARIKR   120               MVFKGGRTET ELALKYLLHR GLPGGRNASV PQILIIVTDG KSQGDVALPS KQLKERGVTV   180               FAVGVRFPRW EELHALASEP RGQHVLLAEQ VEDATNGLFS TLSSSAICSS ATPDCRVEAH   240               PCEHRTLEMV REFAGNAPCW RGSRRTLAVL AAHCPFYSWK RVFLTHPATC YRTTCPGPCD   300               SQPCQNGGTC VPEGLDGYQC LCPLAFGGEA NCALKLSLEC RVDLLFLLDS SAGTTLDGFL   360               RAKVFVKRFV RAVLSEDSRA RVGVATYSRE LLVAVPVGEY QDVPDLVWSL DGIPFRGGPT   420               LTGSALRQAA ERGFGSATRT GQDRPRRVVV LLTESHSEDE VAGPARHARA RELLLLGVGS   480               EAVRAELEEI TGSPKHVMVY SDPQDLFNQI PELQGKLCSR QRPGCRTQAL DLVFMLDTSA   540               SVGPENFAQM QSFVRSCALQ FEVNPDVTQV GLVVYGSQVQ TAFGLDTKPT RAAMLRAISQ   600               APYLGGVGSA GTALLHIYDK VMTVQRGARP GVPKAVVVLT GGRGAEDAAV PAQKLRNNGI   660               SVLVVGVGPV LSEGLRRLAG PRDSLIHVAA YADLRYHQDV LIEWLCGEAK QPVNLCKPSP   720               CMNEGSCVLQ NGSYRCKCRD GWEGPHCENR EWSSCSVCVS QGWILETPLR HMAPVQEGSS   780               RTPPSNYREG LGTEMVPTFW NVCAPGP               Seq ID NO: 24 DNA sequence       Nucleic Acid Accession #: see Table 25 &amp; 25A for complete list               1   11   21   31   41   51       |  |   |    |   |   |       AGGTCGGCTG GTTATCGGGA GTTGGAGGGC TGAGGTCGGG AGGGTGGTGT GTACAGAGCT   60               CTAGGACTCA CGCACCAGGC CAGTCGCGGG TTTTGGGCCG AGGCCTGGGT TACAAGCAGC   120               AAGTGCGCGG TTGGGGCCAC TGCGAGGCCG TTTTAGAAAA CTGTTTAAAA CAAAGAGCAA   180               TTGATGGATA AATCAGGAAT AGATTCTCTT GACCATGTGA CATCTGATGC TGTGGAACTT   240               GCAAATCGAA GTGATAACTC TTCTGATAGC AGCTTATTTA AAACTCAGTG TATCCCTTAC   300               TCACCTAAAG GGGAGAAAAG AAACCCCATT CGAAAATTTG TTCGTACACC TGAAAGTGTT   360               CACGCAAGTA TTCATCAAGT GACTCATCTT TTGAACCAGT ACCATTGACT ATAAAAGCTA   420               TTTTTGAAAG ATTCAAGAAC AGGAAAAAGA GATATAAAAA AAAGAAAAAG AGGAGGTACC   480               AGCCAACAGG AAGACCACGG GGAAGACCAG AAGGAAGGAG AAATCCTATA TACTCACTAA   540               TAGATAAGAA GAAACAATTT AGAAGCAGAG GATCTGGCTT CCCATTTTTA GAATCAGAGA   600               ATGAAAAAAA CGCACCTTGG AGAAAAATTT TAACGTTTGA GCAAGCTGTT GCAAGAGGAT   660               TTTTTAACTA TATTGAAAAA CTGAAGTATG AACACCACCT GAAAGAATCA TTGAAGCAAA   720               TGAATGTTGG TGAAGATTTA GAAAATGAAG ATTTTGACAG TCGTAGATAC AAATTTTTGG   780               ATGATGATGG ATCCATTTCT CCTATTGAGG AGTCAACGCT TTTATCTTGA GGACATGGTG   840               TCTGGAGTTA AAGGTATTGG CATACTCCAC ACATCTGTAC CATTCTTGAG TGATCGCTTA   900               GGAATGAATG TGATTTGGAC TCATTCATGT ATGAGAGTAA GCAATGCTTT TTTTTCCAGG   960               GTGTCAAATT GAGAACCAGG TAGATCCCCA CCACCTACAG TAAAAAGGAC CCTAAAGTAA   1020               ATTGGTTGAA GAAATTAGAT CCCAAAGATT CTTGGTGAAT TTTGAAGTCT TCATCAGTAT   1080               ATCCATATTA AAACGAGATG ACAGAAGCCA AAGTAATTAT GGGCTGACAG GACAACTGGA   1140               TCAGTTTCAT TAAAAAGGGC AAACTTGAAG ATAAATCTTT TGACTCCAGC TCTTTAGAGG   1200               ATCTAAAGTG ACCTTGATGG ACAGTGGAAG AAATCACAAC ATGGAATTCC TCGAATAACA   1260               ATTTATTGAC TTTAAATAAT TTTGTCTAAT GCTACATATA CACAATTAAA AAACCTTTAC   1320               ACTATTTCTA GAAAGTCAGC ATGTATTTTT GGCTCGAAGT TTCTCTAGTT TTTTCTGTGG   1380               AAGGAATAAA AATTTGAGGT TTCAATACAA AAACAAAACA AACAACACGA AACACGAAAA   1440               ACAATCTGTT GTGCGGCGCC CCTGGGCCCC TTGAGAGAAA ACTTTTTAGA ACCCCTTTTG   1500               CGTTGTGGCG GCCCGGGGGC CCCACAGTTG GGTTTAGGTG GGCACCCTTG TGTCTACAAG   1560               TGGTGTCTCC CCAAGAGAGA GAACACCTCC GGGGTCAAGC GGACAACAAG AGTGCGTCGT   1620               GAGGACTCTT CACCCAAAGT ATATAAAACC CGCCCCGCGG GGGAACCACC GGCCGCTTTT   1680               CTGTAGACAC AACCCCCACA GTGGGAACCT CTGAGGGCGC ACACACAGGG CGAGCCTTAT   1740               CAACAAGGGG TGCCCAACAG AAACCCCGAG TTAAAAATCG               Seq ID NO: 25 DNA sequence       Nucleic Acid Accession #: BC001972.1       Coding sequence: 183-1019               1   11   21   31   41   51       |  |   |    |   |   |       GGTCGGCTGG TTATCGGGAG TTGGAGGGCT GAGGTCGGGA GGGTGGTGTG TACAGAGCTC   60               TAGGACTCAC GCACCAGGCC AGTCGCGGGT TTTGGGCCGA GGCCTGGGTT ACAAGCAGCA   120               AGTGCGCGGT TGGGGCCACT GCGAGGCCGT TTTAGAAAAC TGTTTAAAAC AAAGAGCAAT   180               TGATGGATAA ATCAGGAATA GATTCTCTTG ACCATGTGAC ATCTGATGCT GTGGAACTTG   240               CAAATCGAAG TGATAACTCT TCTGATAGCA GCTTATTTAA AACTCAGTGT ATCCCTTACT   300               CACCTAAAGG GGAGAAAAGA AACCCCATTC GAAAATTTGT TCGTACACCT GAAAGTGTTC   360               ACGCAAGTGA TTCATCAAGT GACTCATCTT TTGAACCAAT ACCATTGACT ATAAAAGCTA   420               TTTTTGAAAG ATTCAAGAAC AGGAAAAAGA GATATAAAAA AAAGAAAAAG AGGAGGTACC   480               AGCCAACAGG AAGACCACGG GGAAGACCAG AAGGAAGGAG AAATCCTATA TACTCACTAA   540               TAGATAAGAA GAAACAATTT AGAAGCAGAG GATCTGGCTT CCCATTTTTA GAATCAGAGA   600               ATGAAAAAAA CGCACCTTGG AGAAAAATTT TAACGTTTGA GCAAGCTGTT GCAAGAGGAT   660               TTTTTAACTA TATTGAAAAA CTGAAGTATG AACACCACCT GAAAGAATCA TTGAAGCAAA   720               TGAATGTTGG TGAAGATTTA GAAAATGAAG ATTTTGACAG TCGTAGATAC AAATTTTTGG   780               ATGATGATGG ATCCATTTCT CCTATTGAGG AGTCAACAGC AGAGGATGAG GATGCAACAC   840               ATCTTGAAGA TAACGAATGT GATATCAAAT TGGCAGGGGA TAGTTTCATA GTAAGTTCTG   900               AATTCCCTGT AAGACTGAGT GTATACTTAG AAGAAGAGGA TATTACTGAA GAAGCTGCTT   960               TGTCTAAAAA GAGAGCTACA AAAGCCAAAA ATACTGGACA GAGAGGCCTG AAAATGTGAC   1020               AGGATCATGA ATGTCAAAGG CTTTTATCTT GAGAACATGG TGTCTGGAGT TAAAGGACTA   1080               TTGTTAGATC TGTGGGAAGG AATTACAAGA CAGTTGCTAA AAGTTTGAAA AAGACGGTTG   1140               CTAAACGTTA TGAAAAACCA GATAATCTAC TTTTTTACCT TAGGTATTGG CATACTCCAC   1200               ACATCTGTAC CATTCTTGAG TGATCGCTTA GGAATGAATG TGATTTGAAC TCATTCATGT   1260               TGAGAGGGTG TCAAATTGAG AACCAGGTAG ATCCCCACCA CCTACAGTAA AAAGGACCCT   1320               AAAGTAAATT GGTTGAAGAA ATTAGATCCC AAAGATTCTT GGTGAATTTT GAAGTCTTCA   1380               TCAGTATATC CATATTAAAA CGAGATGACA GAAGCCAAAG TAATTATGGG CTGACAGGAC   1440               AACTGGATCA GTTTCATTAA AAAGGGCAAA CTTGAAGATA AATCTTTTGA CTCCAGCTCT   1500               TTAGAGGATC TAAAGTGACC TTGATGGACA GTGGAAGAAA TCACAACATG GAATTCCTCG   1560               AATAACAATT TATTGACTTT AAATAATTTT GTCTAATGCT ACATATACAC AATTAAAAAA   1620               CCTTTACACT AAAAAAAAAA AAAAAA               Seq ID NO: 26 Protein sequence:       Protein Accession #: AAH01972.1               1   11   21   31   41   51       |  |   |    |   |   |       MDKSGIDSLD HVTSDAVELA NRSDNSSDSS LFKTQCIPYS PKGEKRNPIR KFVRTPESVH   60               ASDSSSDSSF EPIPLTIKAI FERFKNRKKR YKKKKKRRYQ PTGRPRGRPE GRRNPIYSLI   120               DKKKQFRSRG SGFPFLESEN EKNAPWRKIL TFEQAVARGF FNYIEKLKYE HHLKESLKQM   180               NVGEDLENED FDSRRYKFLD DDGSISPIEE STAEDEDATH LEDNECDIKL AGDSFIVSSE   240               FPVRLSVYLE EEDITEEAAL SKKRATKAKN TGQRGLKM               Seq ID NO: 27 DNA sequence       Nucleic Acid Accession #: AK027016       Coding sequence: 207-1043               1   11   21   31   41   51       |  |   |    |   |   |       CTTTTCTTCC GCACGGTTGG AGGAGGTCGG CTGGTTATCG GGAGTTGGAG GGCTGAGGTC   60               GGGAGGGTGG TGTGTACAGA GCTCTAGGAC TCACGCACCA GGCCAGTCGC GGATTTTGGG   120               CCGAGGCCTG GGTTACAAGC AGCAAGTGCG CGGTTGGGGC CACTGCGAGG CCGTTTTAGA   180               AAACTGTTTA AAACAAAGAG CAATTGATGG ATAAATCAGG AATAGATTCT CTTGACCATG   240               TGACATCTGA TGCTGTGGAA CTTGCAAATC GAAGTGATAA CTCTTCTGAT AGCAGCTTAT   300               TTAAAACTCA GTGTATCCCT TACTCACCTA AAGGGGAGAA AAGAAACCCC ATTCGAAAAT   360               TTGTTCGTAC ACCTGAAAGT GTTCACGCAA GTGATTCATC AAGTGACTCA TCTTTTGAAC   420               CAATACCATT GACTATAAAA GCTATTTTTG AAAGATTCAA GAACAGGAAA AAGAGATATA   480               AAAAAAAGAA AAAGAGGAGG TACCAGCCAA CAGGAAGACC ACGGGGAAGA CCAGAAGGAA   540               GGAGAAATCC TATATACTCA CTAATAGATA AGAAGAAACA ATTTAGAAGC AGAGGATCTG   600               GCTTCCCATT TTTAGAATCA GAGAATGAAA AAAACGCACC TTGGAGAAAA ATTTTAACGT   660               TTGAGCAAGC TGTTGCAAGA GGATTTTTTA ACTATATTGA AAAGCTGAAG TATGAACACC   720               ACCTGAAAGA ATCATTGAAG CAAATGAATG TTGGTGAAGA TTTAGAAAAT GAAGATTTTG   780               ACAGTCGTAG ATACAAATTT TTGGATGATG ATGGATCCAT TTCTCCTATT GAGGAGTCAA   840               CAGCAGAGGA TGAGGATGCA ACACATCTTG AAGATAACGA ATGTGATATC AAATTGGCAG   900               GGGATAGTTT CATAGTAAGT TCTGAATTCC CTGTAAGACT GAGTGTATAC TTAGAAGAAG   960               AGGATATTAC TGAAGAAGCT GCTETGTCTA AAAAGAGAGC TACAAAAGCC AAAAATACTG   1020               GACAGAGAGG CCTGAAAATG TGACAGGATC ATGAATGTCA AAGGCTTTTA TCTTGAGAAC   1080               ATGGTGTCTG GAGTTAAAGG TATTGGCATA CTCCACACAT CTGTACCATT CTTGAGTGAT   1140               CGCTTAGGAA TGAATGTGAT TTGAACTCAT TCATGTTGAG AGGGTGTCAA ATTGAGAACC   1200               AGGTAGATCC CCACCACCTA CAGTAAAAAG GACCCTAAAG TAAATTGGTT GAAGAAATTA   1260               GATCCCAAAG ATTCTTGGTG AATTTTGAAG TCTTCATCAG TATATCCATA TTAAAACGAG   1320               ATGACAGAAG CCAAAGTAAT TATGGCAAGT AATGGTTTTT ATCTTAACTA TAAGTTATTT   1380               GCTCAAGGGT GTAATGGTCA TTACCAAGGC TTTTAGAATG CAGTTTCTCA TTTGCTGTGG   1440               ACATGACCAT AAAAAAAAAT TTCCCAGTAG GTTTTCTATC TGCTACGTTG CTAGCAATCA   1500               GCTTATTGGG AACAGTTGAT TAACTGTAAT AGAAATGCAA TACAAATAAA ATGTGAACCA   1560               CATGTGATTT TTCTTTAAAA TCAGTGAGAT TTGAAAATTC TCCTAGATCT CTTGAATCAT   1620               GCAAATTTGC TTTGCCTTTA TATTGTAACC CTTGTGGGTT GCTAATAACC AAGCAGTTTG   1680               TAGTAGAGTT AACTCAGGCT CGTTCTAGGG ACTCATTCAT GTTCACTCAC TGTACACTCA   1740               TCTCTGGAAA TGTAAAATTT ACTTTTATAC TATTGTTATG TAGGGCTGAC AGGACAACTG   1800               GATCAGTTTC ATTAAAAAGG TATGTATGCA TTAGAAAAGA CATTTGTATG GGTCATTTCA   1860               AAGAGGGCTT ATGAGGCTGT GAAACCCAGA GCTCTTAACG CTGTGACCAA AGATGGAAGT   1920               TCTCTATAGG AAGCCATAGC ACTCCTAATG TTTGGTGCTA TGTTTTCCTG AGGAGATATA   1980               AAACGTAATA ATCCATGATT GTTGCCATGT GAGAGTTTTA AAGGTTAATC AAAATTTCTC   2040               TTCTTCAGGG CAAACTTGAA GATAAATCTT TTGACTCCAG CTCTTTAGAG GATCTAAAGT   2100               GACCTTGATG GACAGTGGAA GAAATCACAA CATGGAATTC CTCGAATAAC AATTTATTGA   2160               CTTTAAATAA TTTTGTCTAA TGCTACATAT ACACAATTAA AAAACCTTTA CACTATTTCT   2220               AGAAAGTCAG CATGTATTTT TGGCTCGAAG TTTCTCTAGT GTTTTCTGTG GAAGGAATAA   2280               AAATTTGAGT TTCAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAA               Seq ID NO: 28 Protein sequence:       Protein Accession #: BAB15628.1               1   11   21   31   41   51       |  |   |    |   |   |       MDKSGIDSLD HVTSDAVELA NRSDNSSDSS LFKTQCIPYS PKGEKRNPIR KFVRTPESVH   60               ASDSSSDSSF EPIPLTIKAI FERFKNRKKR YKKKKKRRYQ PTGRPRGRPE GRRNPIYSLI   120               DKKKQFRSRG SGFPFLESEN EKNAPWRKIL TFEQAVARGF FNYIEKLKYE HHLKESLKQM   180               NVGEDLENED FDSRRYKFLD DDGSISPIEE STAEDEDATH LEDNECDIKL AGDSFIVSSE   240               FPVRLSVYLE EEDITEEAAL SKKRATKAKN TGQRGLKM               Seq ID NO: 29 DNA sequence       Nucleic Acid Accession #: NM_004289.3       Coding sequence: 493.1695               1   11   21   31   41   51       |  |   |    |   |   |       GCCGCCGCCT CGTCCACCGG AGGAGCCGGC GCCAGCGTGG ACGGCGGCAG CCAGGCTGTG   60               CAGGGGGGCG GCGGGGACCC CCGAGCGGCT CGGAGTGGCC CCTTGGACGC CGGGGAAGAG   120               GAGAAGGCAC CCGCGGAACC GACGGCTCAG GTGCCGGACG CTGGCGGATG TGCGAGCGAG   180               GAGAATGGGG TACTAAGAGA AAAGCACGAA GCTGTGGATC ATAGTTCCCA GCATGAGGAA   240               AATGAAGAAA GGGTGTCAGC CCAGAAGGAG AACTCACTTC AGCAGAATGA TGATGATGAA   300               AACAAAATAG CAGAGAAACC TGACTGGGAG GCAGAAAAGA CCACTGAATC TAGAAATGAG   360               AGACATCTGA ATGGGACAGA TACTTCTTTC TCTCTGGAAG ACTTATTCCA GTTGCTTTCA   420               TCACAGCCTG AAAATTCACT GGAGGGCATC TCATTGGGAG ATATTCCTCT TCCAGGCAGT   480               ATCAGTGATG GCATGAATTC TTCAGCACAT TATCATGTAA ACTTCAGCCA GGCTATAAGT   540               CAGGATGTGA ATCTTCATGA GGCCATCTTG CTTTGTCCCA ACAATACATT TAGAAGAGAT   600               CCAACAGCAA GGACTTCACA GTCACAAGAA CCATTTCTGC AGTTAAATTC TCATACCACC   660               AATCCTGAGC AAACCCTTCC TGGAACTAAT TTGACAGGAT TTCTTTCACC GGTTGACAAT   720               CATATGAGGA ATCTAACAAG CCAAGACCTA CTGTATGACC TTGACATAAA TATATTTGAT   780               GAGATAAACT TAATGTCATT GGCCACAGAA GACAACTTTG ATCCAATCGA TGTTTCTCAG   840               CTTTTTGATG AACCAGATTC TGATTCTGGC CTTTCTTTAG ATTCAAGTCA CAATAATACC   900               TCTGTCATCA AGTCTAATTC CTCTCACTCT GTGTGTGATG AAGGTGCTAT AGGTTATTGC   960               ACTGACCATG AATCTAGTTC CCATCATGAC TTAGAAGGTG CTGTAGGTGG CTACTACCCA   1020               GAACCCAGTA AGCTTTGTCA CTTGGATCAA AGTGATTCTG ATTTCCATGG AGATCTTACA   1080               TTTCAACACG TATTTCATAA CCACACTTAC CACTTACAGC CAACTGCACC AGAATCTACT   1140               TCTGAACCTT TTCCGTGGCC TGGGAAGTCA CAGAAGATAA GGAGTAGATA CCTTGAAGAC   1200               ACAGATAGAA ACTTGAGCCG TGATGAACAG CGTGCTAAAG CTTTGCATAT CCCTTTTTCT   1260               GTAGATGAAA TTGTCGGCAT GCCTGTTGAT TCTTTCAATA GCATGTTAAG TAGATATTAT   1320               CTGACAGACC TACAAGTCTC ACTTATCCGT GACATCAGAC GAAGAGGGAA AAATAAAGTT   1380               GCTGCGCAGA ACTGTCGTAA ACGCAAATTG GACATAATTT TGAATTTAGA AGATGATGTA   1440               TGTAACTTGC AAGCAAAGAA GGAAACTCTT AAGAGAGAGC AAGCACAATG TAACAAAGCT   1500               ATTAACATAA TGAAACAGAA ACTGCATGAC CTTTATCATG ATATTTTTAG TAGATTAAGA   1560               GATGACCAAG GTAGGCCAGT CAATCCCAAC CACTATGCTC TCCAGTGTAC CCATGATGGA   1620               AGTATCTTGA TAGTACCCAA AGAACTGGTG GCCTCAGGCC ACAAAAAGGA AACCCAAAAG   1680               GGAAAGAGAA AGTGAGAAGA AACTGAAGAT GGACTCTATT ATGTGAAGTA GTAATGTTCA   1740               GAAACTGATT ATTTGGATCA GAAACCATTG AAACTGCTTC AAGAATTGTA TCTTTAAGTA   1800               CTGCTACTTG AATAACTCAG TTAACGCTGT TTTGAAGCTT ACATGGACAA ATGTTTAGGA   1860               CTTCAAGATC ACACTTGTGG GCAATCTGGG GGAGCCACAA CTTTTCATGA AGTGCATTGT   1920               ATACAAAATT CATAGTTATG TCCAAAGAAT AGGTTAACAT GAAAACCCAG TAAGACTTTC   1980               CATCTTGGCA GCCATCCTTT TTAAGAGTAA GTTGGTTACT TCAAAAAGAG CAAACACTGG   2040               GGATCAAATT ATTTTAAGAG GTATTTCAGT TTTAAATGCA AAATAGCCTT ATTTTCATTT   2100               AGTTTGTTAG CACTATAGTG AGCTTTTCAA ACACTATTTT AATCTTTATA TTTAACTTAT   2160               AAATTTTGCT TTCT               Seq ID NO: 30 Protein sequence:       Protein Accession #: NP_004280               1   11   21   31   41   51       |  |   |    |   |   |       MNSSAHYHVN FSQAISQDVN LHEAILLCPN NTFRRDPTAR TSQSQEPFLQ LNSHTTNPEQ   60               TLPGTNLTGF LSPVDNHMRN LTSQDLLYDL DINIFDEINL MSLATEDNFD PIDVSQLFDE   120               PDSDSGLSLD SSHNNTSVIK SNSSHSVCDE GAIGYCTDHE SSSHHDLEGA VGGYYPEPSK   180               LCHLDQSDSD FHGDLTFQHV FHNHTYHLQP TAPESTSEPF PWPGKSQKIR SRYLEDTDRN   240               LSRDEQRAKA LHIPFSVDEI VGMPVDSFNS MLSRYYLTDL QVSLIRDIRR RGKNKVAAQN   300               CRKRKLDIIL NLEDDVCNLQ AKKETLKREQ AQCNKAINIM KQKLHDLYHD IFSRLRDDQG   360               RPVNPNHYAL QCTHDGSILI VPKELVASGH KKETQKGKRK               Seq ID NO: 31 DNA sequence       Nucleic Acid Accession #: NM_033260.1       Coding sequence: 1-1208               1   11   21   31   41   51       |  |   |    |   |   |       ATGAAGTTGG AGGTGTTCGT CCCTCGCGCG GCCCACGGGG ACAAGCAGGG CAGTGACCTG   60               GAGGGCGCGG GCGGCAGCGA CGCGCCGTCC CCGCTGTCGG CGGCGGGAGA CGACTCCCTG   120               GGCTCAGATG GGGACTGCGC GGCCAAGCCG TCCGCGGGCG GCGGCGCCAG AGATACGCAG   180               GGCGACGGCG AACAGAGTGC GGGAGGCGGG CCGGGCGCGG AGGAGGCGAT CCCGGCAGCA   240               GCTGCTGCAG CGGTGGTGGC GGAGGGCGCG GAGGCCGGGG CGGCGGGGCC AGGCGCGGGC   300               GGCGCGGGGA GCGGCGAGGG TGCACGCAGC AAGCCATATA CGCGGCGGCC CAAGCCCCCC   360               TACTCGTACA TCGCGCTCAT CGCCATGGCC ATCCGCGACT CGGCGGGCGG GCGCTTGACG   420               CTGGCGGAGA TCAACGAGTA CCTCATGGGC AAGTTCCCCT TTTTCCGCGG CAGCTACACG   480               GGCTGGCGCA ACTCCGTGCG CCACAACCTT TCGCTCAACG ACTGCTTCGT CAAGGTGCTG   540               CGCGACCCCT CGCGGCCCTG GGGCAAGGAC AACTACTGGA TGCTCAACCC CAACAGCGAG   600               TACACCTTCG CCGACGGGGT CTTCCGCCGC CGCCGCAAGC GCCTCAGCCA CCGCGCGCCG   660               GTCCCCGCGC CCGGGCTGCG GCCCGAGGAG GCCCCGGGCC TCCCCGCCGC CCCGCCGCCC   720               GCGCCCGCCG CCCCGGCCTC GCCCCGCATG CGCTCGCCCG CCCGCCAGGA GGAGCGCGCC   780               AGCCCCGCGG GCAAGTTCTC CAGCTCCTTC GCCATCGACA GCATCCTGCG CAAGCCTTTC   840               CGCAGCCGTC GCCTCAGGGA CACGGCCCCC GGGACGACGC TTCAGTGGGG CGCCGCGCCC   900               TGCCCGCCGC TGCCCGCGTT CCCCGCGCTC CTCCCCGCGG CGCCCTGCAG GGCCCTGCTG   960               CCGCTCTGCG CGTACGGCGC GGGCGAGCCG GCGCGGCTGG GCGCGCGCGA GGCCGAGGTG   1020               CCACCGACCG CGCCGCCCCT CCTGCTTGCA CCTCTCCCGG CGGCGGCCCC CGCCAAGCCA   1080               CTCCGAGGCC CGGCGGCCGG CGGCGCGCAC CTGTACTGCC CCCTGCGGCT GCCCGCAGCC   1140               CTGCAGGCGG CCTTAGTCCG NCGTCCTGGC CCGCACCTGT CGTACCCGGT GGAGACGCTC   1200               CTAGCTTGA               Seq ID NO: 32 Protein sequence:       Protein Accession #: NP_150285.1               1   11   21   31   41   51       |  |   |    |   |   |       MKLEVFVPRA AHGDKQGSDL EGAGGSDAPS PLSAAGDDSL GSDGDCAAKP SAGGGARDTQ   60               GDGEQSAGGG PGAEEAIPAA AAAAVVAEGA EAGAAGPGAG GAGSGEGARS KPYTRRPKPP   120               YSYIALIAMA IRDSAGGRLT LAEINEYLMG KFPFFRGSYT GWRNSVRHNL SLNDCFVKVL   180               RDPSRPWGKD NYWMLNPNSE YTFADGVFRR RRKRLSHRAP VPAPGLRPEE APGLPAAPPP   240               APAAPASPRM RSPARQEERA SPAGKFSSSF AIDSILRKPF RSRRLRDTAP GTTLQWGAAP   300               CPPLPAFPAL LPAAPCRALL PLCAYGAGEP ARLGAREAEV PPTAPPLLLA PLPAAAPAKP   360               LRGPAAGGAH LYCPLRLPAA LQAALVRRPG PHLSYPVETL LA               Seq 0) NO: 33 DNA sequence       Nucleic Acid Accession #: NM_012128.2       Coding sequence: 43-2796               1   11   21   31   41   51       |  |   |    |   |   |       GAACAAACCA ACATTTGAGC CAGGAATAAC TAGAGAGGAA CAATGGGGTT ATTCAGAGGT   60               TTTGTTTTCC TCTTAGTTCT GTGCCTGCTG CACCAGTCAA ATACTTCCTT CATTAAGCTG   120               AATAATAATG GCTTTGAAGA TATTGTCATT GTTATAGATC CTAGTGTGCC AGAAGATGAA   180               AAAATAATTG AACAAATAGA GGATATGGTG ACTACAGCTT CTACGTACCT GTTTGAAGCC   240               ACAGAAAAAA GATTTTTTTT CAAAAATGTA TCTATATTAA TTCCTGAGAA TTGGAAGGAA   300               AATCCTCAGT ACAAAAGGCC AAAACATGAA AACCATAAAC ATGCTGATGT TATAGTTGCA   360               CCACCTACAC TCCCAGGTAG AGATGAACCA TACACCAAGC AGTTCACAGA ATGTGGAGAG   420               AAAGGCGAAT ACATTCACTT CACCCCTGAC CTTCTACTTG GAAAAAAACA AAATGAATAT   480               GGACCACCAG GCAAACTGTT TGTCCATGAG TGGGCTCACC TCCGGTGGGG AGTGTTTGAT   540               GAGTACAATG AAGATCAGCC TTTCTACCGT GCTAAGTCAA AAAAAATCGA AGCAACAAGG   600               TGTTCCGCAG GTATCTCTGG TAGAAATAGA GTTTATAAGT GTCAAGGAGG CAGCTGTCTT   660               AGTAGAGCAT GCAGAATTGA TTCTACAACA AAACTGTATG GAAAAGATTG TCAATTCTTT   720               CCTGATAAAG TACAAACAGA AAAAGCATCC ATAATGTTTA TGCAAAGTAT TGATTCTGTT   780               GTTGAATTTT GTAACGAAAA AACCCATAAT CAAGAAGCTC CAAGCCTACA AAACATAAAG   840               TGCAATTTTA GAAGTACATG GGAGGTGATT AGCAATTCTG AGGATTTTAA AAACACCATA   900               CCCATGGTGA CACCACCTCC TCCACCTGTC TTCTCATTGC TGAAGATCCG TCAAAGAATT   960               GTGTGCTTAG TTCTTGATAA GTCTGGAAGC ATGGGGGGTA AGGACCGCCT AAATCGAATG   1020               AATCAAGCAG CAAAACATTT CCTGCTGCAG ACTGTTGAAA ATGGATCCTG GGTGGGGATG   1080               GTTCACTTTG ATAGTACTGC CACTATTGTA AATAAGCTAA TCCAAATAAA AAGCAGTGAT   1140               GAAAGAAACA CACTCATGGC AGGATTACCT ACATATCCTC TGGGAGGAAC TTCCATCTGC   1200               TCTGGAATTA AATATGCATT TCAGGTGATT GGAGAGCTAC ATTCCCAACT CGATGGATCC   1260               GAAGTACTGC TGCTGACTGA TGGGGAGGAT AACACTGCAA GTTCTTGTAT TGATGAAGTG   1320               AAACAAAGTG GGGCCATTGT TCATTTTATT GCTTTGGGAA GAGCTGCTGA TGAAGCAGTA   1380               ATAGAGATGA GCAAGATAAC AGGAGGAAGT CATTTTTATG TTTCAGATGA AGCTCAGAAC   1440               AATGGCCTCA TTGATGCTTT TGGGGCTCTT ACATCAGGAA ATACTGATCT CTCCCAGAAG   1500               TCCCTTCAGC TCGAAAGTAA GGGATTAACA CTGAATAGTA ATGCCTGGAT GAACGACACT   1560               GTCATAATTG ATAGTACAGT GGGAAAGGAC ACGTTCTTTC TCATCACATG GAACAGTCTG   1620               CCTCCCAGTA TTTCTCTCTG GGATCCCAGT GGAACAATAA TGGAAAATTT CACAGTGGAT   1680               GCAACTTCCA AAATGGCCTA TCTCAGTATT CCAGGAACTG CAAAGGTGGG CACTTGGGCA   1740               TACAATCTTC AAGCCAAAGC GAACCCAGAA ACATTAACTA TTACAGTAAC TTCTCGAGCA   1800               GCAAATTCTT CTGTGCCTCC AATCACAGTG AATGCTAAAA TGAATAAGGA CGTAAACAGT   1860               TTCCCCAGCC CAATGATTGT TTACGCAGAA ATTCTACAAG GATATGTACC TGTTCTTGGA   1920               GCCAATGTGA CTGCTTTCAT TGAATCACAG AATGGACATA CAGAAGTTTT GGAACTTTTG   1980               GATAATGGTG CAGGCGCTGA TTCTTTCAAG AATGATGGAG TCTACTCCAG GTATTTTACA   2040               GCATATACAG AAAATGGCAG ATATAGCTTA AAAGTTCGGG CTCATGGAGG AGCAAACACT   2100               GCCAGGCTAA AATTACGGCC TCCACTGAAT AGAGCCGCGT ACATACCAGG CTGGGTAGTG   2160               AACGGGGAAA TTGAAGCAAA CCCGCCAAGA CCTGAAATTG ATGAGGATAC TCAGACCACC   2220               TTGGAGGATT TCAGCCGAAC AGCATCCGGA GGTGCATTTG TGGTATCACA AGTCCCAAGC   2280               CTTCCCTTGC CTGACCAATA CCCACCAAGT CAAATCACAG ACCTTGATGC CACAGTTCAT   2340               GAGGATAAGA TTATTCTTAC ATGGACAGCA CCAGGAGATA ATTTTGATGT TGGAAAAGTT   2400               CAACGTTATA TCATAAGAAT AAGTGCAAGT ATTCTTGATC TAAGAGACAG TTTTGATGAT   2460               GCTCTTCAAG TAAATACTAC TGATCTGTCA CCAAAGGAGG CCAACTCCAA GGAAAGCTTT   2520               GCATTTAAAC CAGAAAATAT CTCAGAAGAA AATGCAACCC ACATATTTAT TGCCATTAAA   2580               AGTATAGATA AAAGCAATTT GACATCAAAA GTATCCAACA TTGCACAAGT AACTTTGTTT   2640               ATCCCTCAAG CAAATCCTGA TGACATFGAT CCTACTCCTA CTCCTACTCC TACTCCTGAT   2700               AAAAGTCATA ATTCTGGAGT TAATATTTCT ACGCTGGTAT TGTCTGTGAT TGGGTCTGTT   2760               GTAATTGTTA ACTTTATTTT AAGTACCACC ATTTGAACCT TAACGAAGAA AAAAATCTTC   2820               AAGTAGACCT AGAAGAGAGT TTTAAAAAAC AAAACAATGT AAGTAAAGGA TATTTCTGAA   2880               TCTTAAAATT CATCCCATGT GTGATCATAA ACTCATAAAA ATAATTTTAA GATGTCGGAA   2940               AAGGATACTT TGATTAAATA AAAACACTCA TGGATATGTA AAAACTGTCA AGATTAAAAT   3000               TTAATAGTTT CATTTATTTG TTATTTTATT TGTAAGAAAT AGTGATGAAC AAAGATCCTT   3060               TTTCATACTG ATACCTGGTT GTATATTATT TGATGCAACA GTTTTCTGAA ATGATATTTC   3120               AAATTGCATC AAGAAATTAA AATCATCTAT CTGAGTAGTC AAAATACAAG TAAAGGAGAG   3180               CAAATAAACA ACATTTGGAA AAAAAAAAAA AAAAAAAA               Seq ID NO: 34 Protein sequence:       Protein Accession #: NP_036260.1               1   11   21   31   41   51       |  |   |    |   |   |       MGLFRGFVFL LVLCLLHQSN TSFIKLNNNG FEDIVIVIDP SVPEDEKIIE QIEDMVTTAS   60               TYLFEATEKR FFFKNVSILI PENWKENPQY KRPKHENHKH ADVIVAPPTL PGRDEPYTKQ   120               FTECGEKGEY IHFTPDLLLG KKQNEYGPPG KLFVHEWAHL RWGVFDEYNE DQPFYRAKSK   180               KIEATRCSAG ISGRNRVYKC QGGSCLSRAC RIDSTTKLYG KDCQFFPDKV QTEKASIMFM   240               QSIDSVVEFC NEKTHNQEAP SLQNIKCNFR STWEVISNSE DFKNTIPMVT PPPPPVFSLL   300               KIRQRIVCLV LDKSGSMGGK DRLNRMNQAA KHFLLQTVEN GSWVGMVHFD STATIVNKLI   360               QIKSSDERNT LMAGLPTYPL GGTSICSGIK YAFQVIGELH SQLDGSEVLL LTDGEDNTAS   420               SCIDEVKQSG AIVHFIALGR AADEAVIEMS KITGGSHFYV SDEAQNNGLI DAFGALTSGN   480               TDLSQKSLQL ESKGLTLNSN AWMNDTVIID STVGKDTFFL ITWNSLPPSI SLWDPSGTIM   540               ENFTVDATSK MAYLSIPGTA KVGTWAYNLQ AKANPETLTI TVTSRAANSS VPPITVNAKM   600               NKDVNSFPSP MIVYAEILQG YVPVLGANVT AFIESQNGHT EVLELLDNGA GADSFKNDGV   660               YSRYFTAYTE NGRYSLKVRA HGGANTARLK LRPPLNRAAY IPGWVVNGEI EANPPRPEID   720               EDTQTTLEDF SRTASGGAFV VSQVPSLPLP DQYPPSQITD LDATVHEDKI ILTWTAPGDN   780               FDVGKVQRYI IRISASILDL RDSFDDALQV NTTDLSPKEA NSKESFAFKP ENISEENATH   840               IFIAIKSIDK SNLTSKVSNI AQVTLFIPQA NPDDIDPTPT PTPTPDKSHN SGVNISTLVL   900               SVIGSVVIVN FILSTTI               Seq ID NO: 35 DNA sequence       Nucleic Acid Accession #: NM_000901.1       Coding sequence: 217-3171               1   11   21   31   41   51       |  |   |    |   |   |       CGCGGGAGCC AACTTCAGGC TGCTCAGAGG AAGCCCGTGC AGTCAGTCAC CTGGGTGCAA   60               GAGCGTTGCT GCCTCGGGCT CTCCCGCTGC AGGGAGAGCG GCACTCGCTG GCCTGGATGT   120               GGTTGGATTT AGGGGGGCTC CGCAGCAGGG GTTTCGTGGC GGTGGCAAGC GCTGCAACAG   180               GTAGACGGCG AGAGACGGAC CCCGGCCGAG GCAGGGATGG AGACCAAAGG CTACCACAGT   240               CTCCCTGAAG GTCTAGATAT GGAAAGACGG TGGGGTCAAG TTTCTCAGGC TGTGGAGCGT   300               TCTTCCCTGG GACCTACAGA GAGGACCGAT GAGAATAACT ACATGGAGAT TGTCAACGTA   360               AGCTGTGTTT CCGGTGCTAT TCCAAACAAC AGTACTCAAG GAAGCAGCAA AGAAAAACAA   420               GAACTACTCC CTTGCCTTCA GCAAGACAAT AATCGGCCTG GGATTTTAAC ATCTGATATT   480               AAAACTGAGC TGGAATCTAA GGAACTTTCA GCAACTGTAG CTGAGTCCAT GGGTTTATAT   540               ATGGATTCTG TAAGAGATGC TGACTATTCC TATGAGCAGC AGAACCAACA AGGAAGCATG   600               AGTCCAGCTA AGATTTATCA GAATGTTGAA CAGCTGGTGA AATTTTACAA AGGAAATGGC   660               CATCGTCCTT CCACTCTAAG TTGTGTGAAC ACGCCCTTGA GATCATTTAT GTCTGACTCT   720               GGGAGCTCCG TGAATGGTGG CGTCATGCGC GCCATTGTTA AAAGCCCTAT CATGTGTCAT   780               GAGAAAAGCC CGTCTGTTTG CAGCCCTCTG AACATGACAT CTTCGGTTTG CAGCCCTGCT   840               GGAATCAACT CTGTGTCCTC CACCACAGCC AGCTTTGGCA GTTTTCCAGT GCACAGCCCA   900               ATCACCCAGG GAACTCCTCT GACATGCTCC CCTAATGCTG AAAATCGAGG CTCCAGGTCG   960               CACAGCCCTG CACATGCTAG CAATGTGGGC TCTCCTCTCT CAAGTCCGTT AAGTAGCATG   1020               AAATCCTCAA TTTCCAGCCC TCCAAGTCAC TGCAGTGTAA AATCTCCAGT CTCCAGTCCC   1080               AATAATGTCA CTCTGAGATC CTCTGTGTCT AGCCCTGCAA ATATTAACAA CTCAAGGTGC   1140               TCTGTTTCCA GCCCTTCGAA CACTAATAAC AGATCCACGC TTTCCAGTCC GGCAGCCAGT   1200               ACTGTGGGAT CTATCTGTAG CCCTGTAAAC AATGCCTTCA GCTACACTGC TTCTGGCACC   1260               TCTGCTGGAT CCAGTACATT GCGGGATGTG GTTCCCAGTC CAGACACGCA GGAGAAAGGT   1320               GCTCAAGAGG TCCCTTTTCC TAAGACTGAG GAAGTAGAGA GTGCCATCTC AAATGGTGTG   1380               ACTGGCCAGC TTAATATTGT CCAGTACATA AAACCAGAAC CAGATGGAGC TTTTAGCAGC   1440               TCATGTCTAG GAGGAAATAG CAAAATAAAT TCGGATTCTT CATTCTCAGT ACCAATAAAG   1500               CAAGAATCAA CCAAGCATTC ATGTTCAGGC ACCTCTTTTA AAGGGAATCC AACAGTAAAC   1560               CCGTTTCCAT TTATGGATGG CTCGTATTTT TCCTTTATGG ATGATAAAGA CTATTATTCC   1620               CTATCAGGAA TTTTAGGACC ACCTGTGCCC GGCTTTGATG GTAACTGTGA AGGCAGCGGA   1680               TTCCCAGTGG GTATTAAACA AGAACCAGAT GACGGGAGCT ATTACCCAGA GGCCAGCATC   1740               CCTTCCTCTG CTATTGTTGG GGTGAATTCA GGTGGACAGT CCTTCCACTA CAGGATTGGT   1800               GCTCAAGGTA CAATATCTTT ATCACGATCG GCTAGAGACC AATCTTTCCA ACACCTGAGT   1860               TCCTTTCCTC CTGTCAATAC TTTAGTGGAG TCATGGAAAT CACACGGCGA CCTGTCGTCT   1920               AGAAGAAGTG ATGGGTATCC GGTCTTAGAA TACATTCCAG AAAATGTATC AAGCTCTACT   1980               TTACGAAGTG TTTCTACTGG ATCTTCAAGA CCTTCAAAAA TATGTTTGGT GTGTGGGGAT   2040               GAGGCTTCAG GATGCCATTA TGGGGTAGTC ACCTGTGGCA GCTGCAAAGT TTTCTTCAAA   2100               AGAGCAGTGG AAGGGCAACA CAACTATTTA TGTGCTGGAA GAAATGATTG CATCATTGAT   2160               AAGATTCGAC GAAAGAATTG TCCTGCTTGC AGACTTCAGA AATGTCTTCA AGCTGGAATG   2220               AATTTAGGAG CACGAAAGTC AAAGAAGTTG GGAAAGTTAA AAGGGATTCA CGAGGAGCAG   2280               CCACAGCAGC AGCAGCCCCC ACCCCCACCC CCACCCCCGC AAAGCCCAGA GGAAGGGACA   2340               ACGTACATCG CTCCTGCAAA AGAACCCTCG GTCAACACAG CACTGGTTCC TCAGCTCTCC   2400               ACAATCTCAC GAGCGCTCAC ACCTTCCCCC GTTATGGTCC TTGAAAACAT TGAACCTGAA   2460               ATTGTATATG CAGGCTATGA CAGCTCAAAA CCAGATACAG CCGAAAATCT GCTCTCCACG   2520               CTCAACCGCT TAGCAGGCAA ACAGATGATC CAAGTCGTGA AGTGGGCAAA GGTACTTCCA   2580               GGATTTAAAA ACTTGCCTCT TGAGGACCAA ATTACCCTAA TCCAGTATTC TTGGATGTGT   2640               CTATCATCAT TTGCCTTGAG CTGGAGATCG TACAAACATA CGAACAGCCA ATTTCTCTAT   2700               TTTGCACCAG ACCTAGTCTT TAATGAAGAG AAGATGCATC AGTCTGCCAT GTATGAACTA   2760               TGCCAGGGGA TGCACCAAAT CAGCCTTCAG TTCGTTCGAC TGCAGCTCAC CTTTGAAGAA   2820               TACACCATCA TGAAAGTTTT GCTGCTACTA AGCACAATTC CAAAGGATGG CCTCAAAAGC   2880               CAGGCTGCAT TTGAAGAAAT GAGGACAAAT TACATCAAAG AACTGAGGAA GATGGTAACT   2940               AAGTGTCCCA ACAATTCTGG GCAGAGCTGG CAGAGGTTCT ACCAACTGAC CAAGCTGCTG   3000               GACTCCATGC ATGACCTGGT GAGCGACCTG CTGGAATTCT GCTTCTACAC CTTCCGAGAG   3060               TCCCATGCGC TGAAGGTAGA GTTCCCCGCA ATGCTGGTGG AGATCATCAG CGACCAGCTG   3120               CCCAAGGTGG AGTCGGGGAA CGCCAAGCCG CTCTACTTCC ACCGGAAGTG ACTGCCCGCT   3180               GCCCAGAAGA ACTTTGCCTT AAGTTTCCCT GTGTTGTTCC ACACCCAGAA GGACCCAAGA   3240               AAACCTGTTT TTAACATGTG ATGGTTGATT CACACTTGTT CAACAGTTTC TCAAGTTTAA   3300               AGTCATGTCA GAGGTTTGGA GCCGGGAAAG CTGTTTTTCC GTGGATTTGG CGAGACCAGA   3360               GCAGTCTGAA GGATTCCCCA CCTCCAATCC CCCAGCGCTT AGAAACATGT TCCTGTTCCT   3420               CGGGATGAAA AGCCATATCT AGTCAATAAC TCTGATTTTG ATATTTTCAC AGATGGAAGA   3480               AGTTTTAACT ATGCCGTGTA GTTTCTGGTA TCGTTCGCTT GTTTTAAAAG GGTTCAAGGA   3540               CTAACGAACG TTTTAAAGCT TACCCTTGGT TTGCACATAA AACGTATAGT CAATATGGGG   3600               CATTAATATT CTTTTGTTAT TAAAAAAACA CAAAAAAATA ATAAAAAAAT ATATACAGAT   3660               TCCTGTTGTG TAATAACAGA ACTCGTGGCG TGGGGCAGCA GCTGCCTCTG AGCCCTCGCT   3720               CGTCCACGGT CTTCTGCATC ACTGGTATAC ACACTCGTTA GCGTCCATTT CTTATTTAAT   3780               TAGAATGGAT AAGATGATGT TAAATGCCTT GGTTTGATTT CTAGTATCTA TTGTGTTGGC   3840               TTTACAAATA ATTTTTTGCA GTCTTTTGCT GTGCTGTACA TTACTGTATG TATAAATTAT   3900               GAAGGACCTG AAATAAGGTA TAAGGATCTT TTGTAAATGA GACACATACA AAAAAAATCT   3960               TTAATGGTTA ATAGGATGAA TGGGAAAGTA TTTTTGAAAG AATTCTATTT TGCTGGAGAC   4020               TATTTAAGTA CTATCTTTGT CTAAACAAGG TAATTTTTTT TTGTAAAGTG CAATGTCCTG   4080               CATGCATAAT GAACCGTTTA CAGTGTATTT AAGAAAGGGA AAGCTGTGCC TTTTTTAGCT   4140               TCATATCTAA TTTACCATTA TTTTACAGTC TCTGTTGTAA ATAACCACAC TGAAACCTCT   4200               TCGGTTGTCT TGAAACCTTT CTACTTTTTC TGTACTTTTT GTTTTGTTCT TGGTCTCCCG   4260               CTTGGGGCAT TTGTGGGACT CCAGCACGTT TTCTGGCTTC TGCTTCATCC TGCTCCATCG   4320               GGGAATGACA CACTGCGGTG TCTGCAGCTC CTGGAAGGTG TCATTTGACA ACACATGTGG   4380               GAGAGGAGGT CCTTGGAGTG CTGCAGCTTT GGGAAAGCCT GCCTCGTTTC CCTTTTCCTC   4440               TAGAAGCAGA ACCAGCTCTA CGAGAGTGAG ACTGGGAACT TGATGGCTCA GAGAGCATCT   4500               TTTCCTCCCA TTTTAGAAAA TCAGATTTTC TCCTGTGGGA AAAAAAAATT CCATGCACTC   4560               TCTCTCTGTT AAAGATCAGC TATTCCCTTC TGATCTTGGA AAGAGGTTCT GCACTCCTGG   4620               AACCGGTCAC AGGAACGCAC AGATCATGGC AGGATGCGCT GGGACGGCCC ATCTTGGCAA   4680               GGTTCAGTCT GAATGGCATG GAGACCGGGA GATAGAGGGG TTTTAGATTT TTAAAAGGTA   4740               GGTTTTAAAA ATAAGTTTTA TACATAAACA GTTTTGGAGA AAAATTACAG ATCATATAAG   4800               CAAGACAGTG GCACTAAAAT GTTTAATTCA TTAATCTGTT TGTTTGGCAC TGATGCAATG   4860               TATGGCTTTT CTCTTGCCCC AAATCACAAA CATATGTATC TTTGGGGAAA CTAACAATAT   4920               GATTGCACTA AATAAACTAC TTTGAATAGA GGCCAAATTA ATCTTTTAAA AATGATGATA   4980               ATCATCAGGT TTACTCAGTG AAATCATATT AATTATTTTC CAAAATCTAA AAGCTGTAGC   5040               TGGAGAAGCC CATGGCCACG AGGAAGCAGC AATTAATTAG ATCAACACTT TTCTCCAGGG   5100               TTCACCATGC AGGCAACATT ACCTTGTCTT TCAAAAGACA CCTGCCTTAG TGCAAGGGGA   5160               AACCTGTGAA AGCTGCACTC AGAGGGAGGA GTCTTTCTTA CATAATTTGC AATTTCAGGA   5220               ATTTAATTTA TAGGCAGATC TTTAAATACA GTCAACTTAC GGTGCACAGT AATATGAAAG   5280               CCACACTTTG AAGGTAATAA ATACACAGCA TGCAGACTGG GAGTTGCTAG CAAACAAATG   5340               GCTTACTTAC AAAAGCAGCT TTTAGTTCAG ACTTAGTTTT TATAAAATGA GAATTCTGAC   5400               TTACTTAACC AGGTTTGGGA TGGAGATGGT CTGCATCAGC TTTTTGTATT AACAAAGTTA   5460               CTGGCTCTTT GTGTGTCTCC AGGTAACTTT GCTTGATTAA ACAGCAAAGC CATATTCTAA   5520               ATTCACTGTT GAATGCCTGT CCCAGTCCAA ATTGTCTGTC TGCTCTTATT TTTGTACCAT   5580               ATTGCTCTTA AAAATCTTGG TTTGGTACAG TTCATAATTC ACCAAAAAGT TCATATAATT   5640               TAAAGAAACA CTAAATTAGT TTAAAATGAA GCAATTTATA TCTTTATGCA AAAACATATG   5700               TCTGTCTTTG CAAAGGACTG TAAGCAGATT ACAATAAATC CTTTACTTT               Seq ID NO: 36 Protein sequence:       Protein Accession #: NP_000892.1               1   11   21   31   41   51       |  |   |    |   |   |       METKGYHSLP EGLDMERRWG QVSQAVERSS LGPTERTDEN NYMEIVNVSC VSGAIPNNST   60               QGSSKEKQEL LPCLQQDNNR PGILTSDIKT ELESKELSAT VAESMGLYMD SVRDADYSYE   120               QQNQQGSMSP AKIYQNVEQL VKFYKGNGHR PSTLSCVNTP LRSFMSDSGS SVNGGVMRAI   180               VKSPIMCHEK SPSVCSPLNM TSSVCSPAGI NSVSSTTASF GSFPVHSPIT QGTPLTCSPN   240               AENRGSRSHS PAHASNVGSP LSSPLSSMKS SISSPPSHCS VKSPVSSPNN VTLRSSVSSP   300               ANINNSRCSV SSPSNTNNRS TKSSPAASTV GSICSPVNNA FSYTASGTSA GSSTLRDVVP   360               SPDTQEKGAQ EVPFPKTEEV ESAISNGVTG QLNIVQYIKP EPDGAFSSSC LGGNSKINSD   420               SSFSVPIKQE STKHSCSGTS FKGNPTVNPF PFMDGSYFSF MDDKDYYSLS GILGPPVPGF   480               DGNCEGSGFP VGIKQEPDDG SYYPEASIPS SAIVGVNSGG QSFHYRIGAQ GTISLSRSAR   540               DQSFQHLSSF PPVNTLVESW KSHGDLSSRR SDGYPVLEYI PENVSSSTLR SVSTGSSRPS   600               KICLVCGDEA SGCHYGVVTC GSCKVFFKRA VEGQHNYLCA GRNDCIIDKI RRKNCPACRL   660               QKCLQAGMNL GARKSKKLGK LKGIHEEQPQ QQQPPPPPPP PQSPEEGTTY IAPAKEPSVN   720               TALVPQLSTI SRALTPSPVM VLENIEPEIV YAGYDSSKPD TAENLLSTLN RLAGKQMIQV   780               VKWAKVLPGF KNLPLEDQIT LIQYSWMCLS SFALSWRSYK HTNSQFLYFA PDLVFNEEKM   840               HQSAMYELCQ GMHQISLQFV RLQLTFEEYT IMKVLLLLST IPKDGLKSQA AFEEMRTNYI   900               KELRKMVTKC PNNSGQSWQR FYQLTKLLDS MHDLVSDLLE FCFYTFRESH ALKVEFPAML   960               VEIISDQLPK VESGNAKPLY FHRK               Seq ID NO: 37 DNA sequence       Nucleic Acid Accession #: see Table 25 &amp; 25A for complete list               1   11   21   31   41   51       |  |   |    |   |   |       CCTACCAGGT TCAAGCAACT CTGCTGCCTC AGCTCCCAAG TAGCTGGGAT TACAGGTGCA   60               TGCCACTACA CCTGGCTTTT TGTATTTTTA GTAGAGATGG TTTTCACTAT GTTGGCCAGG   120               CTGATCTTGA ATTCCTGGCC TGAAGTAATC TGCCTGCCTC AGCCTCCCAA AGTGCTGGGA   180               TTATAGGAGC CACCACACCT GGCATAACTG GTATTTTTTA TATGCTTCCT GGGCAACTTA   240               AAAAATTGAT TACTCTGTTG TTTCTTCCTT TTTTTTTTTT TTTTGGCTTT GACCAATTTG   300               TGAGACCCAA GTATCTCCTA CCTAGAAAAA AAACACACTA AACAGTAAAT GATTACCAAC   360               CTATTTGGAA CAAATCTCAA TTAATTAACA TATACTTCAA GGAGAAGACT TAACAAAATC   420               TTACTTTTCA TTCTTAATAG CTCTTTCCAT AAAAATGTTC CACAAGTGTA TCAAATTAGT   480               CCTAACAACT ACTGTTAAGT GATTAATGAA ACAGGAGTGA CAGGAGTGAA TTTAATAATA   540               GCAATAAATA CAGATGGGAC TACATAAATT GTGGAGGTCC TGATGCAAAA CTCTCTCTGT   600               ATTCGATGGC ATCTCAGCTT TCTCATAGAG CTGTTTCACT GTGAGGGTCT TTATCCTTCA   660               TGCAGAGCTT CATTATTTTC TTTCTTCTAG CAATCAGTCC AAAGCACAAT GTCAGAAAGA   720               TCACAACACA TGCAGCAATA ATGGGCTCTA TTGGTACACC CACAGTTTTA TCTTTAACAA   780               TC               Seq ID NO: 38 DNA sequence       Nucleic Acid Accession #: NM_001192.1       Coding sequence: 219-773               1   11   21   31   41   51       |  |   |    |   |   |       AAGACTCAAA CTTAGAAACT TGAATTAGAT GTGGTATTCA AATCCITACG TGCCGCGAAG   60               ACACAGACAG CCCCCGTAAG AACCCACGAA GCAGGCGAAG TTCATTGTTC TCAACATTCT   120               AGCTGCTCTT GCTGCATTTG CTCTGGAATT CTTGTAGAGA TATTACTTGT CCTTCCAGGC   180               TGTTCTTTCT GTAGCTCCCT TGT3TTCTTT TTGTGATCAT GTTGCAGATG GCTGGGCAGT   240               GCTCCCAAAA TGAATATTTT GACAGTTTGT TGCATGCTTG CATACCTTGT CAACTTCGAT   300               GTTCTTCTAA TACTCCTCCT CTAACATGTC AGCGTTATTG TAATGCAAGT GTGACCAATT   360               CAGTGAAAGG AACGAATGCG ATTCTCTGGA CCTGTTTGGG ACTGAGCTTA ATAATTTCTT   420               TGGCAGTITT CGTGCTAATG TTTTTGCTAA GGAAGATAAG CTCTGAACCA TTAAAGGACG   480               AGTTTAAAAA CACAGGATCA GGTCTCCTGG GCATGGCTAA CATTGACCTG GAAAAGAGCA   540               GGACTGGTGA TGAAATTATT CTTCCGAGAG GCCTCGAGTA CACGGTGGAA GAATGCACCT   600               GTGAAGACTG CATCAAGAGC AAACCGAAGG TCGACTCTGA CCATTGCTTT CCACTCCCAG   660               CTATGGAGGA AGGCGCAACC ATTCTTGTCA CCACGAAAAC GAATGACTAT TGCAAGAGCC   720               TGCCAGCTGC TTTGAGTGCT ACGGAGATAG AGAAATCAAT TTCTGCTAGG TAATTAACCA   780               TTTCGAcTCG AGCAGTGCCA CTTTAAAAAT CTTTTGTCAG AATAGATGAT GTGTCAGATC   840               TCTTTAGGAT GACTGTATTT TTCAGTTGCC GATACAGCTT TTTGTCCTCT AACTGTGGAA   900               ACTCTTTATG TTAGATATAT TTCTCTAGGT TACTGTTGGG AGCTTAATGG TAGAAACTTC   960               CTTGGTTTCA TGATTAAAGT CTTTTTTTTT CCTGA               Seq ID NO: 39 Protein sequence:       Protein Accession #: NP_001183.1               1   11   21   31   41   51       |  |   |    |   |   |       MLQMAGQCSQ NEYFDSLLHA CIPCQLRCSS NTPPLTCQRY CNASVTNSVK GTNAILWTCL   60               GLSLIISLAV FVLMFLLRKI SSEPLKDEFK NTGSGLLGMA NIDLEKSRTG DEIILPRGLE   120               YTVEECTCED CIKSKPKVDS DHCFPLPAME EGATILVTTK TNDYCKSLPA ALSATEIEKS   180               ISAR               Seq ID NO: 40 DNA sequence       Nucleic Acid Accession #: NM_025087.1       Coding sequence: 183-2282               1   11   21   31   41   51       |  |   |    |   |   |       ACACTGCCTC GGTFCGGCAA GTGGGTCAGT TGGCTGGGGC TCACTTGGCA ACGGGACGCG   60               GGAACGAGGG GCGCGGACGC AGGCCCGGGA GGACGCGGCG GCGGGAACCT GGGGGCGCAG   120               GGCTAGGGCA GCGGGCCCGA CCCGCACGGC TTTCCTGGAA AGCGCTGCCC CTCGCCGCGG   180               CGATGACCTC GCTGTGGAGA GAAATCCTCT TGGAGTCGCT GCTGGGATGT GTTTCTTGGT   240               CTCTCTACCA TGACCTGGGA CCGATGATCT ATTACTTTCC TTTGCAAACA CTAGAACTCA   300               CTGGGCTTGA AGGTTTTAGT ATAGCATTTC TTTCTCCAAT ATTCCTAACA ATTACTCCTT   360               TCTCGAAATT GGTTAACAAG AAGTGGATGC TAACCCTGCT GAGGATAATC ACTATTGGCA   420               GCATAGCCTC CTTCCAGGCT CCAAATGCCA AACTTCGACT GATGGTTCTT GCGCTTGGGG   480               TGTCTTCCTC ACTGATAGTG CAAGCTGTGA CTTGGTGGTC AGGAAGTCAT TTGCAAAGGT   540               ACCTCAGAAT TTGGGGATTC ATTTTAGGAC AGATTGTTCT TGTTGTTCTA CGCATATGGT   600               ATACTTCACT AAACCCAATC TGGAGTTATC AGATGTCCAA CAAAGTGATA CTGACATTAA   660               GTGCCATAGC CACACTTGAT CGTATTGGCA CAGATGGTGA CTGCAGTAAA CCTGAAGAAA   720               AGAAGACTGG TGAGGTAGCC ACGGGGATGG CCTCTAGACC CAACTGGCTG CTGGCAGGGG   780               CTGCTTTTGG TAGCCTTGTG TTCCTCACCC ACTGGGTTTT TGGAGAAGTC TCTCTTGTTT   840               CCAGATGGGC AGTGAGTGGG CATCCACATC CAGGGCCAGA TCCTAACCCA TTTGGAGGTG   900               CAGTACTGCT GTGCTTGGCA AGTGGATTGA TGCTTCCATC TTGTTTGTGG TTTCGTGGTA   960               CTGGTTTGAT CTGGTGGGTT ACAGGAACAG CTTCAGCTGC GGGGCTCCTT TACCTGCACA   1020               CATGGGCAGC TGCTGTGTCT GGCTGTGTCT TCGCCATCTT TACTGCATCC ATGTGGCCCC   1080               AAACACTTGG ACACCTTATT AACTCAGGGA CAAACCCTGG GAAAACCATG ACCATTGCCA   1140               TGATATTTTA TCTTCTAGAA ATATTTTTCT GTGCCTGGTG CACAGCTTTT AAGTTTGTCC   1200               CAGGAGGTGT CTACGCTAGA GAAAGATCAG ATGTGCTTTT GGGGACAATG ATGTTAATTA   1260               TCGGGCTGAA TATGCTATTT GGTCCTAAGA AAAACCTTGA TTTGCTTCTT CAAACAAAAA   1320               ACAGTTCTAA AGTGCYTTTC AGAAAGAGTG AAAAATACAT GAAACTTTTT CTGTGGCTGC   1380               TTGTTGGTGT GGGATTGTTG GGATTAGGAC TACGGCATAA AGCCTATGAG AGAAAACTGG   1440               GCAAAGTGGC ACCAACCAAA GAGGTCTCTG CTGCCATCTG GCCTTTCAGG TTTGGATATG   1500               ACAATGAAGG GTGGTCTAGT CTAGAAAGAT CAGCTCACCT GCTCAATGAA ACAGGTGCAG   1560               ATTTCATAAC AATTTTGGAG AGTGATGCTT CTAAGCCCTA TATGGGGAAC AATGACTTAA   1620               CCATGTGGCT AGGGGAAAAG TTGGGTTTCT ATACAGACTT TGGTCCAAGC ACAAGGTATC   1680               ACACTTGGGG GATTATGGCT TTGTCAAGAT ACCCAATTGT GAAATCTGAG CATCACCTTC   1740               TTCCGTCACC AGAGGGCGAG ATCGCACCAG CCATCACATT GACCGTTAAC ATTTCGGGCA   1800               AGCTGGTGGA TTTTGTCGTG ACACACTTTG GGAACCACGA AGATGACCTC GACAGGAAAC   1860               TGCAGGCTAT TGCTGTTTCA AAACTACTGA AAAGTAGCTC TAATCAAGTG ATATTTCTGG   1920               GATATATCAC TTCAGCACCT GGCTCCAGAG ATTATCTACA GCTCACTGAA CATGGCAATG   1980               TGAAGGATAT CGACAGCACT GATCATGACA GATGGTGTGA ATACATTATG TATCGAGGGC   2040               TGATCAGGTT GGGTTATGCA AGAATCTCCC ATGCTGAACT GAGTGATTCA GAAATTCAGA   2100               TGGCAAAATT TAGGATCCCT GATGACCCCA CTAATTATAG AGACAACCAG AAAGTGGTCA   2160               TAGACCACAG AGAAGTTTCT GAGAAAATTC ATTTTAATCC CAGATTTGGA TCCTACAAAG   2220               AAGGACACAA TTATGAAAAC AACCATAATT TTCATATGAA TACTCCCAAA TACTTTTTAT   2280               GAAACATTTA AAACAAGAAG TTATTGGCTG GGAAAATCTA AGAAAAAAAG TATGTAAGAT   2340               AAAAAGAAGA GATTAATGAA AGTGGGAAAA TACACATGAA GAACCTCAAC TTAAAAAACA   2400               CATGGTATCT ATGCAGTGGG AAATTACCTC CATTTGTAAA CTATGTTGCT TAATAAAAAC   2460               ATTTCTCTAA AAAAAAAAAA AAAAAA               Seq ID NO: 41 Protein sequence:       Protein Accession #: NP_079363.1               1   11   21   31   41   51       |  |   |    |   |   |       MTSLWREILL ESLLGCVSWS LYHDLGPMIY YFPLQTLELT GLEGFSIAFL SPIFLTITPF   60               WKLVNKKWML TLLRIITIGS IASFQAPNAK LRLMVLALGV SSSLIVQAVT WWSGSHLQRY   120               LRIWGFILGQ IVLVVLRIWY TSLNPIWSYQ MSNKVILTLS AIATLDRIGT DGDCSKPEEK   180               KTGEVATGMA SRPNWLLAGA AFGSLVFLTH WVFGEVSLVS RWAVSGHPHP GPDPNPFGGA   240               VLLCLASGLM LPSCLWFRGT GLIWWVTGTA SAAGLLYLHT WAAAVSGCVF AIFTASMWPQ   300               TLGHLINSGT NPGKTMTIAM IFYLLEIFFC AWCTAFKFVP GGVYARERSD VLLGTMMLII   360               GLNMLFGPKK NLDLLLQTKN SSKVLFRKSE KYMKLFLWLL VGVGLLGLGL RHKAYERKLG   420               KVAPTKEVSA AIWPFRFGYD NEGWSSLERS AHLLNETGAD FITILESDAS KPYMGNNDLT   480               MWLGEKLGFY TDFGPSTRYH TWGIMALSRY PIVKSEHHLL PSPEGEIAPA ITLTVNISGK   540               LVDFVVTHFG NHEDDLDRKL QAIAVSKLLK SSSNQVIFLG YITSAPGSRD YLQLTEHGNV   600               KDIDSTDHDR WCEYIMYRGL IRLGYARISH AELSDSEIQM AKFRIPDDPT NYRDNQKVVI   660               DHREVSEKIH FNPRFGSYKE GHNYENNHNF HMNTPKYFL                    
     [0362] It is understood that the examples described above in no way serve to limit the true scope of this invention, but rather are presented for illustrative purposes. All publication, sequences of accession numbers, and patent applications cited in this specification are herein incorporated by reference as if each individual publication or patent application were specifically and individually indicated to be incorporated by reference.