Patent Publication Number: US-2010119533-A1

Title: Polynucleotides and Polypeptides Identified by IVIAT Screening and Methods of Use

Description:
CROSS-REFERENCE TO RELATED APPLICATIONS 
     This application claims the benefit of U.S. Provisional Application Ser. No. 60/893,537, filed Mar. 7, 2007, and Ser. No. 60/972,413, filed Sep. 14, 2007, the disclosures of which are hereby incorporated by reference in their entireties, including all figures, tables and amino acid or nucleic acid, sequences. 
    
    
     GOVERNMENT SUPPORT 
     The subject matter of this application has been supported by research grants from the National Institute of Dental and Craniofacial Research (NIH/NIDCR) under grant numbers 1RO1DE13980-01 and 1R21DE015069-01 A1 and the National Institute of Allergy and Infectious Diseases (NIH/NIAID) under grant number PO1A1061537-01. Accordingly, the government has certain rights in this invention. 
    
    
     BACKGROUND OF THE INVENTION 
       Candida  spp. are major causes of systemic infections among hospitalized patients in the developed world, particularly among immunosuppressed patients. Candidemia, for example, is the fourth most common bloodstream infection in the United States and is associated with attributable mortality as high as 40-50% despite treatment with antifungal agents (Edmond, M B et al.  Clin Infect Dis.,  1999; 29:239-44; Gudlaugsson, O et al.  Clin Infect Dis.,  2003; 37:1172-7). The management of systemic candidiasis is complicated by the limitations of current diagnostic tests. Blood cultures, generally taken as the gold standard for the diagnosis of candidemia, are negative in up to 50% of autopsy-proven cases of disseminated candidiasis (Berenguer, J et al.  Diagn Microbiol Infect Dis.,  1993; 17:103-9). Moreover, blood cultures that are positive often become so late in the disease course (Ellepola, A N and Morrison, C J  J Microbiol.,  2005; 43:65-84; Morris, A J et al.  J Clin Microbiol.,  1996; 34:1583-5), which delays appropriate therapy. Such delays in the institution of an antifungal agent are associated with significantly increased mortality rates among patients with candidemia (Morrell, M et al.  Antimicrob Agents Chemother.,  2005; 49:3640-5; Garey, K W et al.  Clin Infect Dis.,  2006 Jul 1; 43:25-31). Cultures of deep tissue sites are even more problematic, and require invasive sampling procedures, which are difficult to perform and are often contra-indicated in patients at high-risk for systemic candidiasis. Because of these shortcomings, there is great interest in non-culture based diagnostic tests. 
     Investigators have assessed a wide range of potential diagnostic markers, including the detection of candidal nucleic acids, metabolites such as D-arabinitol, cell wall components such as β-D-glucan, and antigens such as secreted aspartyl proteinase (Sap), enolase and mannan (Ellepola, A N and Morrison, C J  J Microbiol.,  2005; 43:65-84). Despite individual reports of reasonable diagnostic yield for each of these tests, none have been broadly validated or accepted in widespread clinical practice. There has been less enthusiasm for antibody detection as a diagnostic strategy because of concerns for false negative tests in immunocompromised patients and false-positive tests resulting from prior exposure to commensal  Candida  spp. (Quindos, G et al.  Rev Iberoam Micol.,  2004; 21(1)). Nevertheless, recent studies detecting antibodies against Sap (Na B K and Song C Y  Clin Diagn Lab Immunol.,  1999; 6:924-9; Morrison C J et al.  Clin Diagn Lab Immunol.,  2003; 10:835-48; Yang Q et al.  Mycoses,  2007; 50:165-71), enolase (van Deventer, A J et al.  Microbiol Immunol.,  1996; 40:125-31; Mitsutake, K et al.  J Clin Microbiol.,  1996; 1918-21; Lain, A et al.  Clin Vaccine Immunol.,  2007; 14:318-9), hyphal wall protein 1 (Lain, A et al.  Clin Vaccine Immunol.,  2007; 14:318-9), mannan (Sendid, B et al.  J Clin Microbiol.,  1999; 37:1510-7; Yera, H et al.  Eur J Clin Microbiol Infect Dis.,  2001; 20:864-70), a 52 kDa metalloprotein (El Moudni, B et al.  Clin Diagn Lab Immunol.,  1998; 5:823-5), and a  C. albicans  germ-tube antigen (CTGA) (Quindos, G et al.  Rev Iberoam Micol.,  2004; 21(1); Lain, A et al.  Clin Vaccine Immunol.,  2007; 14:318-9) have reported sensitivities and specificities that are consistent with other diagnostic markers, even among highly immunocompromised hosts like stem cell transplant and liver transplant recipients (Hoppe, J E et al.  Mycoses,  1995; 38:41-9; Klingspor, L et al.  Acta Paediatr.,  1995; 84:424-8; Navarro, D et al.  Eur J Clin Microbiol Infect Dis.,  1993; 12:839-46; Tollemar, J et al.  Scand J Infect Dis.,  1989; 21:205-12; Villalba, R. et al.  Eur J Clin Microbiol Infect Dis.,  1993; 12:347-9). Moreover, various combinations of antibody test with an antigen test have been shown to be superior to either test alone in diagnosing systemic candidiasis (Sendid, B et al.  J Med Microbial.,  2002; 51:433-42; Sendid, B et al.  J Clin Microbial.,  2004; 42:164-71; Pazos, C et al.  Rev Iberoam Micol.,  2006; 23:209-15). 
     Despite shortcomings, cultures of blood or sterile sites remain the gold-standard for diagnosing systemic candidiasis. Alternative diagnostic markers including antibody detection have been developed, but none have been widely accepted in clinical practice. Clearly, much work remains to be done in developing diagnostic markers; antibody detection strategies merit exploration as part of these endeavors. 
     In Vivo Induced Antigen Technology (IVIAT) is a technique that identifies pathogen antigens that are immunogenic and expressed in vivo during human infection (Rollins et al.,  Cell. Microbial.,  2005, 7(1):1-9; Richardson et al.,  J. Med. Microbial.,  2005, 54:497-5-4; John et al.,  Infection and Immunity,  2005, 73(5):2665-2679; Hang et al.,  PNAS,  2003, 100(14):8508-8513; International Publication No. WO 01/11081 (Progulskefox et al.)). IVIAT is complementary to other techniques that identify genes and their products expressed in vivo. Genes and gene pathways identified by IVIAT can play a role in virulence or pathogenesis during human infection, and may be appropriate for inclusion in therapeutic, vaccine, or diagnostic applications. 
     BRIEF SUMMARY OF THE INVENTION 
     Selected genes expressed during the course of infection encode immunogenic proteins that represent targets for novel diagnostic tests. The present inventors identified over 60 immunogenic  C. albicans  proteins using an antibody-based screening method. In Vivo Induced Antigen Technology (IVIAT) was used to identify immunogenic  Candida  and  Aspergillus  proteins that may be targets for novel therapeutics, diagnostics, and vaccines (Handfield M. et al.,  Trends Microbial.,  2000, 8:336-339, which is incorporated herein by reference in its entirety). 
     In brief, sera were pooled from 24 HIV-infected patients with active candidiasis. Serum from a patient was also collected after he had recovered from IA. The present inventors repeatedly adsorbed the sera against  Candida albicans  or  Aspergillus fumigatus  cells and cell lysates. Using ELISA, it was demonstrated that repeated rounds of adsorption reduced overall anti- Candida  and anti- Aspergillus  antibody titers. The adsorbed sera was then used to screen  C. albicans  and  A. fumigatus  genomic DNA expression libraries. After identifying colonies that were consistently reactive with antibodies in the sera, genes encoding the immunogenic proteins were identified by searching genome sequencing databases. To date, the present inventors have identified 69  C. albicans  and 14  A. fumigatus  genes and their corresponding proteins (see Tables 7-8, which lists  C. albicans  and  A. fumigatus  genes and proteins, including GenBank accession numbers).  A. fumigatus  screening in on-going. Furthermore, the  C. albicans  and  A. fumigatus  nucleic acids and polypeptides, and the pathogenic conditions associated with the nucleic acids and/or polypeptides (such as disseminated candidiasis, oropharyngeal candidiasis, vulvovaginal candidiasis, etc.), referenced in Raman et al.,  Molecular Microbiology,  60(3):697-709; Cheng et al.,  Infection and Immunity,  2005, 73(11):7190-7197; Badrane et al.,  Microbiology,  2005, 151:2923-2931; Nguyen et al.,  Med. Mycol.,  2004, 42(4):293-304; Cheng et al.,  Molecular Microbiology,  2003, 48(5):1275-1288; and Cheng et al.,  Infection and Immunity,  2003, 71(19):6101-6103, are incorporated herein by reference. 
     Since the  C. albicans  and  A. fumigatus  genes and proteins identified by the present inventors&#39; screening are reactive with antibodies from humans infected with the organisms, it is expected that they are promising targets for novel therapeutics, diagnostics, and vaccines. 
     The  Candida  and  Aspergillus  polypeptides of the invention have been found to be immunogenic and are useful as diagnostic test antigens. The polypeptide antigens of the subject invention can provide the basis of a diagnostic assay that would allow the rapid, in-house, laboratory diagnosis of infection with  Candida  and/or  Aspergillus  using a sample (e.g., adsorbed or unadsorbed serum, plasma, or whole blood) from an infected human or animal. Additionally, the subject invention provides methods of detecting the presence of  Candida albicans  and/or  Aspergillus fumigatus  in biological or environmental samples utilizing antibodies provided by the subject invention. Furthermore, the use of single antigens or, more preferably, one or more groups of antigens of the invention in the diagnosis of these important diseases offers many advantages including enhanced test specificity, ease of testing and consistency of results using synthetically or recombinantly produced test antigens instead of cultured, whole organisms. In one embodiment of each aspect of the invention, the one or more antigens (e.g., one, two, three, four, five, or six or more antigens) is among those polypeptides disclosed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 herein, or among those polypeptides encoded by the nucleic acids disclosed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, or 17 herein. In another embodiment, the one or more antigens (e.g., one, two, three, four, five, or six or more antigens) are from  C. albicans  and selected from the group among Set1p, Rbt4p, Met6p, BGl2p, Gap1, Bgl2, Car1, Enol1, Fba1, IPF9162, PGK1, and Muc1. In another embodiment, the one or more antigens (e.g., one, two, three, or four or more antigens) are from  C. albicans  and selected from among Set1p, Rbt4p, Met6p, and BGl2p. In another embodiment, the one or more antigens (e.g., one, two, three, four, or five or more antigens) are from  C. albicans  and selected from among Set1p, Rbt4p, Met6p, BGl2p, and Gap1. In another embodiment, the one or more antigens (e.g., one, two, three, or four or more antigens) are from  C. albicans  and selected from among Car1, Enol1, Fba1, and IPF9162. In another embodiment, the antigen is from  C. albicans  and is PGK1. In another embodiment, the antigen is from  C. albicans  and is Muc1. 
     The inventors have used a human antibody-based screening strategy to identify  C. albicans  genes that encode immunogenic proteins, including previously uncharacterized virulence factors (Cheng, S et al.  Mol Microbiol.,  2003; 48:1275-88; Nguyen, M H et al.  Med Mycol.,  2004; 42:293-304). 12 proteins were chosen to study as targets for antibody detection assays. These proteins can be classified into four groups according to their cellular localizations and functions: classic cell wall proteins; glycolytic enzymes localized to the cell wall; intracellular proteins localized to cell wall; and intracellular proteins, likely not localized to cell wall (Table 9). The objectives were to determine if serum antibody responses against any of the recombinant antigens could reliably distinguish patients with systemic candidiasis from un-infected controls. The inventors also sought to derive a predictive model for systemic candidiasis that considered antibody responses against multiple antigens. 
     In this study, ELISA was used to measure serum antibody responses against 15 recombinant  Candida albicans  antigens among patients with systemic candidiasis due to a variety of  Candida  spp. (n=60) and un-infected controls (n=24). IgG responses were better than IgM in differentiating patients with systemic candidiasis from controls. The inventors tested a prediction model including serum IgG responses against all 15 antigens, and identified patients with systemic candidiasis with an error rate of 3.7%, sensitivity of 96.6% and specificity of 95.6%. Furthermore, a subset of 4 antigens (SET1, ENO1, PGK1-2 and MUC1-2) identified through backwards elimination and canonical correlation analyses performed as accurately as the full panel. Using that simplified model, systemic candidiasis could be predicted in a test sample of 32 patients with 100% sensitivity and 87.5% specificity. These findings show that detection of antibodies against a panel of candidal antigens represents an advance in the diagnosis of systemic candidiasis. Accordingly, in another embodiment, the one or more antigens (e.g., one, two, three, or four or more antigens) are from  C. albicans  and selected from among SET1 (chromatin regulatory protein), ENO1 (enolase I), PGK1-2 (phosphoglycerate kinease), and MUC1-2 (cell surface glycoprotein). In another embodiment, the antigen is from  C. albicans  and is SET1. In another embodiment, the antigen is from  C. albicans  and is ENO1. In another embodiment, the antigen is from  C. albicans  and is PGK1-2. In another embodiment, the antigen is from  C. albicans  and is MUC1-2. 
     In another embodiment, the antigen is from  C. albicans  and is one or more polypeptides (e.g., one, two, three, four, five, six, seven, eight, nine, ten, eleven, twelve, thirteen, fourteen, or fifteen or more polypeptides) selected from among METE-1, MET6-2, NOT5, RBT4, IPF9162, CAR1, GAP1, SET1, ENO1, FBA1, PGK1-1, PGK1-2, MUC1-1, MUC1-2, and BGL2. 
     In another embodiment, the antigen is from  C. albicans  and is one or more polypeptides (e.g., one, two, three, four, five, six, or seven or more polypeptides) selected from among SET1, ENO1, FBA1, PGK1-1, PGK1-2, MUC1-2, and BGL2. 
    
    
     
       BRIEF DESCRIPTION OF THE DRAWINGS 
         FIG. 1  shows a pie chart of portals of entry of fungemia. 
         FIGS. 2A-2F  show representative IgG responses against specific  Candida  proteins. 
         FIGS. 3A and 3B  are graphs showing IgM and IgG titers, respectively, against specific proteins among patients with systemic candidiasis and controls. 
     
    
    
     BRIEF DESCRIPTION OF THE SEQUENCES 
     SEQ ID NO: 1 is the sense primer for MET6-1. 
     SEQ ID NO: 2 is the anti-sense primer for MET6-1. 
     SEQ ID NO: 3 is the sense primer for MET6-2. 
     SEQ ID NO: 4 is the anti-sense primer for MET6-2. 
     SEQ ID NO: 5 is the sense primer for RBT4. 
     SEQ ID NO: 6 is the anti-sense primer for RBT4. 
     SEQ ID NO: 7 is the sense primer for IPF9162. 
     SEQ ID NO: 8 is the anti-sense primer for IPF9162. 
     SEQ ID NO: 9 is the sense primer for CAR1. 
     SEQ ID NO: 10 is the anti-sense primer for CAR1. 
     SEQ ID NO: 11 is the sense primer for GAP1. 
     SEQ ID NO: 12 is the anti-sense primer for GAP1. 
     SEQ ID NO: 13 is the sense primer for ENO1. 
     SEQ ID NO: 14 is the anti-sense primer for ENO1. 
     SEQ ID NO: 15 is the sense primer for BGL2. 
     SEQ ID NO: 16 is the anti-sense primer for BGL2. 
     SEQ ID NO: 17 is the sense primer for FBA1. 
     SEQ ID NO: 18 is the anti-sense primer for FBA1. 
     SEQ ID NO: 19 is the sense primer for MUC1-1. 
     SEQ ID NO: 20 is the anti-sense primer for MUC1-1. 
     SEQ ID NO: 21 is the sense primer for MUC1-2. 
     SEQ ID NO: 22 is the anti-sense primer for MUC1-2. 
     SEQ ID NO: 23 is the sense primer for PGK1-1. 
     SEQ ID NO: 24 is the anti-sense primer for PGK1-1. 
     SEQ ID NO: 25 is the sense primer for PGK1-2. 
     SEQ ID NO: 26 is the anti-sense primer for PGK1-2. 
     DETAILED DESCRIPTION OF THE INVENTION 
     In Vivo Induced Antigen Technology (IVIAT) was used to identify immunogenic  Candida  and  Aspergillus  proteins that may be targets for novel therapeutics, diagnostics, and vaccines (Handfield M. et al.,  Trends Microbiol.,  2000, 8:336-339, which is incorporated herein by reference in its entirety). 
     The subject invention provides: 
     a) one or more: 
     1) isolated, purified, and/or recombinant polypeptides comprising those listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein; 
     2) isolated, purified, and/or recombinant polypeptides (e.g., one, two, three, or four or more polypeptides) selected from among SET1 (chromatin regulatory protein), ENO1 (enolase I), PGK1-2 (phosphoglycerate kinease), and MUC1-2 (cell surface glycoprotein); or 
     3) one or more polypeptides (e.g., one, two, three, four, five, six, seven, eight, nine, ten, eleven, twelve, thirteen, fourteen, or fifteen or more polypeptides) selected from among MET6-1, METE-2, NOT5, RBT4, IPF9162, CAR1, GAP1, SET1, ENO1, FBA1, PGK1-1, PGK1-2, MUC1-1, MUC1-2, and BGL2; or 
     4) one or more polypeptides (e.g., one, two, three, four, five, six, or seven or more polypeptides) selected from among SET1, ENO1, FBA1, PGK1-1, PGK1-2, MUC1-2, and BGL2; or 
     5) variant polypeptides having at least about 20% to 99.99% identity, preferably at least 60% to 99.99% identity to the polypeptide of listed in the tables disclosed herein and which have at least one of the activities associated with the polypeptides listed in tables 7-8 disclosed herein; 
     6) a fragment of the polypeptide(s) listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein, or a variant polypeptide, wherein the polypeptide fragment or fragment of the variant polypeptide has substantially the same activity as the full length polypeptides listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein; 
     7) a multimeric polypeptide construct comprising a series of repeating elements that are, optionally, joined together by linker elements, wherein said repeating elements are selected from one, or more, of the polypeptides listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein; 
     8) an epitope of a polypeptide selected from those listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein; 
     9) a multi-epitope construct comprising at least one epitope as set forth herein; or 
     10) a polypeptide according to embodiments a(1), a(2), a(3), a(4), a(5), a(6), a(7), a(8), or a(9) that further comprises a heterologous polypeptide sequence; 
     b) a composition comprising a carrier and a polypeptide as set forth in a(1), a(2), a(3), a(4), a(5), a(6), a(7), a(8), a(9), or a(10) wherein said carrier is an adjuvant or a pharmaceutically acceptable excipient; 
     c) methods of detecting the presence of antibodies in a subject infected with  Candida  and/or  Aspergillus  (e.g.,  Candida albicans  and/or  Aspergillus fumigatus ) comprising contacting a biological sample with a polypeptide or polypeptides as set forth in a(1), a(2), a(3), a(4), a(5), a(6), a(7), a(8), a(9), or a(10) and detecting the presence of an antigen/antibody complex; and 
     d) an improvement in methods of diagnosing or detecting an  Candida  and/or  Aspergillus  (e.g.,  Candida albicans  and/or  Aspergillus fumigatus )  Candida  and/or  Aspergillus  (e.g.,  Candida albicans  and/or  Aspergillus fumigatus ) infection in a subject, wherein the improvement comprises the use of an isolated, purified, and/or recombinant polypeptide as set forth in a(1), a(2), a(3), a(4), a(5), a(6), a(7), a(8), a(9), or a(10) in an immunoassay for the detection or diagnosis of an  Candida  and/or  Aspergillus  infection. 
     In one embodiment of each of the aforementioned aspects of the invention a)-d), the one or more polypeptides (e.g., one, two, three, four, five, or six or more polypeptides) is among those polypeptides disclosed in. Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 herein, or among those polypeptides encoded by the nucleic acids disclosed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, or 17 herein. In another embodiment, the one or more polypeptides (e.g., one, two, three, four, five, or six or more polypeptides) are from  C. albicans  and selected from the group consisting of Set1p, Rbt4p, Met6p, BGl2p, Gap1, Bgl2, Car1, Enol1, Fba1, IPF9162, PGK1, and Muc1. In another embodiment, the one or more polypeptides (e.g., one, two, three, or four polypeptides) are from  C. albicans  and selected from the group consisting of Set1p, Rbt4p, Met6p, and BGl2p. In another embodiment, the one or more polypeptides (e.g., one, two, three, four, or five polypeptides) are from  C. albicans  and selected from the group consisting of Set1p, Rbt4p, Met6p, BGl2p, and Gap1. In another embodiment, the one or more polypeptides (e.g., one, two, three, or four polypeptides) are from  C. albicans  and selected from the group consisting of Car1, Enol1, Fba1, and IPF9162. In another embodiment, the polypeptide is from  C. albicans  and is PGK1. In another embodiment, the polypeptide is from  C. albicans  and is Muc1. The disclosed polypeptides and variants therof contain one or more eptitopes that are specifically bound by antibodies in adsorbed or unadsorbed serum. 
     In another embodiment, the one or more antigens (e.g., one, two, three, or four or more antigens) are from  C. albicans  and selected from among SET1 (chromatin regulatory protein), ENO1 (enolase I), PGK1-2 (phosphoglycerate kinease), and MUC1-2 (cell surface glycoprotein). In another embodiment, the antigen is from  C. albicans  and is SET1. In another embodiment, the antigen is from  C. albicans  and is ENO1. In another embodiment, the antigen is from  C. albicans  and is PGK1-2. In another embodiment, the antigen is from  C. albicans  and is MUC1-2. 
     In another embodiment, the antigen is from  C. albicans  and is one or more polypeptides (e.g., one, two, three, four, five, six, seven, eight, nine, ten, eleven, twelve, thirteen, fourteen, or fifteen or more polypeptides) selected from among METE-1, MET6-2, NOT5, RBT4, IPF9162, CAR1, GAP1, SET1, ENO1, FBA1, PGK1-1, PGK1-2, MUC1-1, MUC1-2, and BGL2. 
     In another embodiment, the antigen is from  C. albicans  and is one or more polypeptides (e.g., one, two, three, four, five, six, or seven or more polypeptides) selected from among SET1, ENO1, FBA1, PGK1-1, PGK1-2, MUC1-2, and BGL2. 
     In the context of the instant invention, the terms “oligopeptide”, “polypeptide”, “peptide” and “protein” can be used interchangeably to refer to a chain of two or more amino acids; however, it should be understood that the invention does not relate to the polypeptides in natural form, that is to say that they are not in their natural environment but that the polypeptides may have been isolated or obtained by purification from natural sources or obtained from host cells prepared by genetic manipulation (e.g., the polypeptides, or fragments thereof, are recombinantly produced by host cells, or by chemical synthesis). Polypeptides according to the instant invention may also contain non-natural amino acids, as will be described below. The terms “oligopeptide”, “polypeptide”, “peptide” and “protein” are also used, in the instant specification, to designate a series of residues, typically L-amino acids, connected one to the other, typically by peptide bonds between the a-amino and carboxyl groups of adjacent amino acids. Linker elements can be joined to the polypeptides of the subject invention through peptide bonds or via chemical bonds (e.g., heterobifunctional chemical linker elements) as set forth below. Additionally, the terms “amino acid(s)” and “residue(s)” can be used interchangeably. 
     Thus, the subject invention provides polypeptides comprising those listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein and/or polypeptide fragments of those polypeptides. In some embodiments of the subject invention, polypeptide fragments of the subject invention are epitopes that are bound by antibodies or T-cell receptors are designated “epitopes”; in the context of the subject invention, “epitopes” are considered to be a subset of the invention designated as “fragments of invention”. 
     Polypeptide fragments (and/or epitopes) according to the subject invention, usually comprise a contiguous span of or at least 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, and up to one amino acid less than the full length polypeptides of the invention. 
     Polypeptide fragments of the subject invention can be any integer in length from at least 3, preferably 4, and more preferably 5 consecutive amino acids to 1 amino acid less than a full length polypeptide of those listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein. The term “integer” is used herein in its mathematical sense and thus representative integers include, for example: 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, and so on. 
     Each polypeptide fragment of the subject invention can also be described in terms of its N-terminal and C-terminal positions. For example, combinations of N-terminal to C-terminal fragments of 6 contiguous amino acids to 1 amino acid less than the full length polypeptide are included in the present invention. Thus, for example, a 6 consecutive amino acid fragment could occupy positions selected from the group consisting of 1-6, 2-7, 3-8, 4-9, 5-10, 6-11, 7-12, 8-13, 9-14, 10-15, 11-16, 12-17, 13-18, 14-19, 15-20, 16-21, 17-22, 18-23, 19-24, 20-25, 21-26, 22-27, 23-28, 24-29, 25-30, 26-31, 27-32, 28-33, 29-34, 30-35, 31-36, 32-37, 33-38, 34-39, 35-40, 36-41, 37-42, 38-43, 39-44, 40-45, 41-46, 42-47, 43-48, 44-49, 45-50, 46-51, 47-52, 48-53, 49-54, 50-55, 51-56, 52-57, 53-58, 54-59, 55-60, 56-61, 57-62, 58-63, 59-64, 60-65, 61-66, 62-67, 63-68, 64-69, 65-70, 66-71, 67-72, 68-73, and 69-74. 
     Fragments, as described herein, can be obtained by cleaving the polypeptides of the invention with a proteolytic enzyme (such as trypsin, chymotrypsin, or collagenase) or with a chemical reagent, such as cyanogen bromide (CNBr). Alternatively, polypeptide fragments can be generated in a highly acidic environment, for example at pH 2.5 or by other means (see, e.g., Kolaskar, A S and Tongaonkar, P C [1990],  FEBS Letters  276: 172-174; Parker, J M R, Guo, D and Hodges, R S [1986]  Biochemistry  25: 5425-5432; and/or Saha, S and Raghava, G. P. S. [2006]  Proteins  65(1):40-48). Such polypeptide fragments may be equally well prepared by chemical synthesis or using hosts transformed with an expression vector according to the invention. The transformed host cells contain a nucleic acid, allowing the expression of these fragments, under the control of appropriate elements for regulation and/or expression of the polypeptide fragments. 
     In certain preferred embodiments, fragments of the polypeptides disclosed herein retain at least one property or activity of the full-length polypeptide from which the fragments are derived. Thus, fragments of the polypeptide have one or more of the following properties or activities: a) the ability to: 1) specifically bind to adsorbed or unadsorbed antibodies specific for the full length polypeptide; and/or 2) specifically bind antibodies found in an animal or human infected with  Candida  and/or  Aspergillus ; b) the ability to bind to, and activate T-cell receptors (CTL (cytotoxic T-lymphocyte) and/or HTL (helper T-lymphocyte receptors)) in the context of MHC Class I or Class II antigen that are isolated or derived from an animal or human infected with  Candida  and/or  Aspergillus;  3) the ability to induce an immune response in an animal or human; and/or 4) the ability to induce a protective immune response in an animal or human against  Candida  and/or  Aspergillus.    
     The polypeptides, and fragments thereof, may further comprise linker elements (L) that facilitate the attachment of the fragments to other molecules, amino acids, or polypeptide sequences. The linkers can also be used to attach the polypeptides, or fragments thereof, to solid support matrices for use in affinity purification protocols. Non-limiting examples of “linkers” suitable for the practice of the invention include chemical linkers (such as those sold by Pierce, Rockford, Ill.), or peptides that allow for the connection combinations of polypeptides (see, for example, linkers such as those disclosed in U.S. Pat. Nos. 6,121,424, 5,843,464, 5,750,352, and 5,990,275, hereby incorporated by reference in their entirety). 
     In other embodiments, the linker element (L) can amino acid sequences. In other embodiments, the peptide linker has one or more of the following characteristics: a) it allows for the free rotation of the polypeptides that it links (relative to each other); b) it is resistant or susceptible to digestion (cleavage) by proteases; and c) it does not interact with the polypeptides it joins together. In various embodiments, a multimeric construct according to the subject invention includes a peptide linker and the peptide linker is 5 to 60 amino acids in length. More preferably, the peptide linker is 10 to 30, amino acids in length; even more preferably, the peptide linker is 10 to 20 amino acids in length. In some embodiments, the peptide linker is 17 amino acids in length. 
     Peptide linkers suitable for use in the subject invention are made up of amino acids selected from the group consisting of Gly, Ser, Asn, Thr and Ala. Preferably, the peptide linker includes a Gly-Ser element. In a preferred embodiment, the peptide linker comprises (Ser-Gly-Gly-Gly-Gly) y  wherein y is 1, 2, 3, 4, 5, 6, 7, or 8. Other embodiments provide for a peptide linker comprising ((Ser-Gly-Gly-Gly-Gly) y -Ser-Pro). In certain preferred embodiments, y is a value of 3, 4, or 5. In other preferred embodiment, the peptide linker comprises (Ser-Ser-Ser-Ser-Gly) y  or ((Ser-Ser-Ser-Ser-Gly) y -Ser-Pro), wherein y is 1, 2, 3, 4, 5, 6, 7, or 8. In certain preferred embodiments, y is a value of 3, 4, or 5. Where cleavable linker elements are desired, one or more cleavable linker sequences such as Factor Xa or enterokinase (Invitrogen, San Diego Calif.) can be used alone or in combination with the aforementioned linkers 
     Multimeric constructs of the subject invention typically comprise a series of repeating elements, optionally interspersed with other elements. As would be appreciated by one skilled in the art, the order in which the repeating elements occur in the multimeric polypeptide is not critical and any arrangement of the repeating elements as set forth herein can be provided by the subject invention. Thus, a “multimeric construct” according to the subject invention can provide a multimeric polypeptide comprising a series of polypeptides, polypeptide fragments, or epitopes that are, optionally, joined together by linker elements (either chemical linker elements or amino acid linker elements). 
     A “variant polypeptide” (or polypeptide variant) is to be understood to designate polypeptides exhibiting, in relation to the natural polypeptide, certain modifications. These modifications can include a deletion, addition, or substitution of at least one amino acid, a truncation, an extension, a chimeric fusion, a mutation, or polypeptides exhibiting post-translational modifications. Among these homologous variant polypeptides, are those comprising amino acid sequences exhibiting between at least (or at least about) 20.00% to 99.99% (inclusive) identity to the full length, native, or naturally occurring polypeptide are another aspect of the invention. The aforementioned range of percent identity is to be taken as including, and providing written description and support for, any fractional percentage, in intervals of 0.01%, between 20.00% and, up to, including 99.99%. These percentages are purely statistical and differences between two polypeptide sequences can be distributed randomly and over the entire sequence length. Thus, variant polypeptides can have 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, or 99 percent identity with the polypeptide sequences of the instant invention. In a preferred embodiment, a variant or modified polypeptide exhibits at least 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, or 99 percent identity to one of those listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein. Typically, the percent identity is calculated with reference to the full-length, native, and/or naturally occurring polypeptide. In all instances, variant polypeptides retain at least one of the activities associated with the native polypeptide. In some embodiments, variant polypeptides retain at least 2, and preferably all of the activities associated with the native polypeptide. 
     Variant polypeptides can also comprise one or more heterologous polypeptide sequences (e.g., tags that facilitate purification of the polypeptides of the invention (see, for example, U.S. Pat. No. 6,342,362, hereby incorporated by reference in its entirety; Altendorf et al. [1999-WWW, 2000] “Structure and Function of the F o  Complex of the ATP Synthase from  Escherichia Coli,” J. of Experimental Biology  203:19-28, The Co. of Biologists, Ltd., G. B.; Baneyx [1999] “Recombinant Protein Expression in  Escherichia coli ,” Biotechnology 10:411-21, Elsevier Science Ltd.; Eihauer et al. [2001] “The FLAG™ Peptide, a Versatile Fusion Tag for the Purification of Recombinant Proteins,”  J. Biochem Biophys Methods  49:455-65; Jones et al. [1995]  J. Chromatography  707:3-22; Jones et al. [1995] “Current Trends in Molecular Recognition and Bioseparation,”  J. of Chromatography A.  707:3-22, Elsevier Science B. V.; Margolin [2000] “Green Fluorescent Protein as a Reporter for Macromolecular Localization in Bacterial Cells,”  Methods  20:62-72, Academic Press; Puig et al. [2001] “The Tandem Affinity Purification (TAP) Method: A General Procedure of Protein Complex Purification,”  Methods  24:218-29, Academic Press; Sassenfeld [1990] “Engineering Proteins for Purification,” TibTech 8:88-93; Sheibani [1999] “Prokaryotic Gene Fusion Expression Systems and Their Use in Structural and Functional Studies of Proteins,”  Prep. Biochem.  &amp;  Biotechnol.  29(1):77-90, Marcel Dekker, Inc.; Skerra et al. [1999] “Applications of a Peptide Ligand for Streptavidin: the Strep-tag”,  Biomolecular Engineering  16:79-86, Elsevier Science, B. V.; Smith [1998] “Cookbook for Eukaryotic Protein Expression: Yeast, Insect, and Plant Expression Systems,” The Scientist 12(22):20; Smyth et al. [200] “Eukaryotic Expression and Purification of Recombinant Extracellular Matrix Proteins Carrying the Strep II Tag”,  Methods in Molecular Biology,  139:49-57; Unger [1997] “Show Me the Money: Prokaryotic Expression Vectors and Purification Systems,”  The Scientist  11(17):20, each of which is hereby incorporated by reference in their entireties), or commercially available tags from vendors such as such as STRATAGENE (La Jolla, Calif.), NOVAGEN (Madison, Wis.), QIAGEN, Inc., (Valencia, Calif.), or InVitrogen (San Diego, Calif.). 
     In other embodiments, polypeptides of the subject invention can be fused to heterologous polypeptide sequences that have adjuvant activity (a polypeptide adjuvant). Non-limiting examples of such polypeptides include heat shock proteins (hsp) (see, for example, U.S. Pat. No. 6,524,825, the disclosure of which is hereby incorporated by reference in its entirety). 
     Also included within the scope of the subject invention are at least one or more polypeptide fragments that are an “epitope” or which contain one or more epitope. In the context of the subject invention, an the term “epitope” is used to designate a series of residues, typically L-amino acids, connected one to the other, typically by peptide bonds between the α-amino and carboxyl groups of adjacent amino acids. The preferred CTL (or CD8 +  T cell)-inducing peptides of the invention are 13 residues or less in length and usually consist of between about 8 and about 11 residues (e.g., 8, 9, 10 or 11 residues), preferably 9 or 10 residues. The preferred HTL (or CD4 +  T cell)-inducing peptides are less than about 50 residues in length and usually consist of between about 6 and about 30 residues, more usually between about 12 and 25 (e.g., 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24 or 25), and often between about 15 and 20 residues (e.g., 15, 16, 17, 18, 19 or 20). 
     The nomenclature used to describe peptide compounds follows the conventional practice wherein the amino group is presented to the left (the N-terminus) and the carboxyl group to the right (the C-terminus) of each amino acid residue. The L-form of an amino acid residue is represented by a capital single letter or a capital first letter of a three-letter symbol, and the D-form, for those amino acids having D-forms, is represented by a lower case single letter or a lower case three letter symbol. Glycine has no asymmetric carbon atom and is simply referred to as “Gly” or G. Symbols for the amino acids are as follows: (Single Letter Symbol; Three Letter Symbol Amino Acid) A; Ala; Alanine: C; Cys; Cysteine: D; Asp; Aspartic Acid: E; Glu; Glutamic Acid: F; Phe; Phenylalanine: G; Gly; Glycine: H; His; Histidine: I; Ile; Isoleucine: K; Lys; Lysine: L; Leu; Leucine: M; Met; Methionine: N; Asn; Asparagine: P; Pro; Proline: Q; Gln; Glutamine: R; Arg; Arginine: S; Ser; Serine: T; Thr; Threonine: V; Val; Valine: W; Trp; Tryptophan: Y; Tyr; Tyrosine. Amino acid “chemical characteristics” are defined as: Aromatic (F, W, Y); Aliphatic-hydrophobic (L, I, V, M); Small polar (S, T, C); Large polar (Q, N); Acidic (D, E); Basic (R, H, K); Non-polar: (P, A, G) Proline; Alanine; and Glycine. By way of example, amino acid substitutions can be carried out without resulting in a substantial modification of the associated activity (or activities) of the corresponding modified polypeptides; for example, the replacement of leucine with valine or isoleucine, of aspartic acid with glutamic acid, of glutamine with asparagine, of arginine with lysine, and the like, the reverse substitutions can be performed without substantial modification of the biological activity of the polypeptides. 
     In order to extend the life of the polypeptides according to the invention, it may be advantageous to use non-natural amino acids, for example in the D-form, or alternatively amino acid analogs, for example sulfur-containing forms of amino acids in the production of “variant polypeptides”. Alternative means for increasing the life of polypeptides can also be used in the practice of the instant invention. For example, polypeptides of the invention, and fragments thereof, can be recombinantly modified to include elements that increase the plasma, or serum half-life of the polypeptides of the invention. These elements include, and are not limited to, antibody constant regions (see for example, U.S. Pat. No. 5,565,335, hereby incorporated by reference in its entirety, including all references cited therein), or other elements such as those disclosed in U.S. Pat. Nos. 6,319,691, 6,277,375, or 5,643,570, each of which is incorporated by reference in its entirety, including all references cited within each respective patent. Alternatively, the polynucleotides and genes of the instant invention can be recombinantly fused to elements, well known to the skilled artisan, that are useful in the preparation of immunogenic constructs for the purposes of vaccine formulation. 
     The subject invention also provides biologically active fragments of a polypeptide according to the invention and includes those peptides capable of eliciting an immune response directed against  Candida  and/or  Aspergillus , the immune response providing components (B-cells, antibodies, and/or or components of the cellular immune response (e.g., helper, cytotoxic, and/or suppressor T-cells)) reactive with the fragment of the polypeptide; the intact, full length, unmodified polypeptide disclosed herein; or both a fragment of a polypeptide and the intact, full length, unmodified polypeptides disclosed herein. 
     The subject application also provides a composition comprising at least one isolated, recombinant, or purified polypeptide as set forth herein and at least one additional component. In various aspects of the invention, the additional component is a solid support (for example, microtiter wells, magnetic beads, non-magnetic beads, agarose beads, glass, cellulose, plastics, polyethylene, polypropylene, polyester, nitrocellulose, nylon, or polysulfone) and/or a pharmaceutically acceptable excipient or adjuvant known to those skilled in the art. In some aspects of the invention, the solid support provides an array of polypeptides of the subject invention or an array of polypeptides comprising combinations of various polypeptides of the subject invention. Compositions of the subject invention can also comprise additional antigens of interest. 
     In one embodiment, the subject invention provides methods for eliciting an immune response in a subject comprising the administration of compositions comprising polypeptides according to the subject invention to a subject in amounts sufficient to induce an immune response in the subject. In some embodiments, a “protective” or “therapeutic immune response” is induced in the subject. A “protective immune response” or “therapeutic immune response” refers to a CTL (or CD8 +  T cell) and/or an HTL (or CD4 +  T cell), and/or an antibody response to an antigen derived from an infectious agent or a tumor antigen, which in some way prevents or at least partially arrests disease symptoms, side effects or progression. The protective immune response may also include an antibody response that has been facilitated by the stimulation of helper T cells (or CD4 +  T cells). Additional methods of inducing an immune response in an individual are taught in U.S. Pat. No. 6,419,931, hereby incorporated by reference in its entirety. The term CTL can be used interchangeably with CD8 +  T-cell(s) and the term HTL can be used interchangeably with CD4 +  T-cell(s) throughout the subject application. 
     The terms “individual” and “subject” are used interchangeably to include mammals, such as apes, chimpanzees, orangutans, humans, monkeys or domesticated animals (pets) such as dogs, cats, guinea pigs, hamsters, Vietnamese pot-bellied pigs, rabbits, ferrets, cows, horses, goats and sheep. In a preferred embodiment, the methods of inducing an immune response contemplated herein are practiced on humans. 
     The composition administered to the subject may, optionally, contain an adjuvant and may be delivered in any manner known in the art for the delivery of immunogen to a subject. Compositions may also be formulated in any carriers, including for example, pharmaceutically acceptable carriers such as those described in E. W. Martin&#39;s  Remington&#39;s Pharmaceutical Science,  Mack Publishing Company, Easton, Pa. In preferred embodiments, compositions may be formulated in incomplete Freund&#39;s adjuvant, complete Freund&#39;s adjuvant, or alum. 
     In other embodiments, the subject invention provides for diagnostic assays based upon Western blot formats or standard immunoassays known to the skilled artisan. For example, antibody-based assays such as enzyme linked immunosorbent assays (ELISAs), radioimmunoassays (RIAs), lateral flow assays, reversible flow chromatographic binding assay (see, for example, U.S. Pat. No. 5,726,010, which is hereby incorporated by reference in its entirety), immunochromatographic strip assays, automated flow assays, and assays utilizing peptide- or antibody-containing biosensors may be employed for the detection of: 1) the polypeptides, and fragments thereof, provided by the subject invention; or 2) antibodies that bind to the polypeptides or fragments thereof, provided by the subject invention. Such assays and methods for conducting the assays are well-known in the art and the methods may test biological samples (e.g., serum, plasma, or blood) or environmental samples (e.g., soil, food, water) qualitatively (presence or absence of polypeptide) or quantitatively (comparison of a sample against a standard curve prepared using a polypeptide of the subject invention) for the presence of: a) one or more polypeptide of the subject invention, or 2) antibodies that bind to polypeptides of the subject invention. The detection of antibodies in adsorbed or unadsorbed samples derived from an individual using the polypeptides (and/or combinations thereof) disclosed in this application is an indication that the individual may have an active infection. 
     The subject invention provides a method of detecting a  Candida  and/or  Aspergillus  in a biological sample from a subject, comprising assessing the presence of a polypeptide or nucleic acid molecule encoding the polypeptide, in the sample; wherein the presence of the nucleic acid molecule or polypeptide is indicative of the presence of  Candida  and/or  Aspergillus  or an active infection by these organisms (e.g., is a marker associated with infection by one or both of these organisms). In one embodiment, the polypeptide is one or more polypeptides (e.g., one, two, three, or four or more antigens) selected from among SET1 (chromatin regulatory protein), ENO1 (enolase I), PGK1-2 (phosphoglycerate kinease), and MUC1-2 (cell surface glycoprotein). 
     In one embodiment, the subject invention provides a method of detecting a  Candida  and/or  Aspergillus  polypeptide, variant, or fragment of said polypeptide or variant (e.g., to detect an infection or monitor a known infection), comprising contacting a sample with an antibody that specifically binds to: 1) a polypeptide, or fragment thereof, or 2) a variant, or a fragment thereof, and detecting the presence of an antibody-antigen complex. Alternatively, the subject invention provides a method of detecting antibodies to  Candida  and/or  Aspergillus  comprising contacting a sample from a subject with: 1) a polypeptide of the subject invention, or fragment thereof, or 2) a variant of the subject invention, or a fragment thereof, and detecting the presence of an antibody-antigen complex. A sample can comprise a blood, serum, or tissue sample from an individual infected by  Candida  and/or  Aspergillus . Alternatively, a sample can comprise culture medium in which polypeptides of the subject invention (or fragments thereof) are expressed or transformed host cells (lysed or intact cells) expressing polypeptides (or fragments thereof) that are provided by the subject invention. 
     In one embodiment of the method of detecting a  Candida  and/or  Aspergillus  polypeptide, variant, or fragment, the one or more polypeptides (e.g., one, two, three, four, five, or six or more polypeptides) is among those polypeptides disclosed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 herein, or among those polypeptides encoded by the nucleic acids disclosed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, or 17 herein. In another embodiment, the one or more polypeptides (e.g., one, two, three, four, five, or six or more polypeptides) are from  C. albicans  and selected from the group consisting of Set1p, Rbt4p, Met6p, BGl2p, Gap1, Bgl2, Carl, Enol1, Fba1, IPF9162, PGK1, and Muc1. In another embodiment, the one or more polypeptides (e.g., one, two, three, or four polypeptides) are from  C. albicans  and selected from the group consisting of Set1p, Rbt4p, Met6p, and BGl2p. In another embodiment, the one or more polypeptides (e.g., one, two, three, four, or five polypeptides) are from  C. albicans  and selected from the group consisting of Set1p, Rbt4p, Met6p, BGl2p, and Gap1. In another embodiment, the one or more polypeptides (e.g., one, two, three, or four polypeptides) are from  C. albicans  and selected from the group consisting of Car1, Enol1, Fba1, and IPF9162. In another embodiment, the polypeptide is from  C. albicans  and is PGK1. In another embodiment, the polypeptide is from  C. albicans  and is Muc1. 
     In another embodiment, the one or more antigens (e.g., one, two, three, or four or more antigens) are from  C. albicans  and selected from among SET1 (chromatin regulatory protein), ENO1 (enolase I), PGK1-2 (phosphoglycerate kinease), and MUC1-2 (cell surface glycoprotein). In another embodiment, the antigen is from  C. albicans  and is SET1. In another embodiment, the antigen is from  C. albicans  and is ENO1. In another embodiment, the antigen is from  C. albicans  and is PGK1-2. In another embodiment, the antigen is from  C. albicans  and is MUC1-2. 
     The  Candida  or  Aspergillus  infection detected or monitored using the methods of the invention can be of various types, such as invasive aspergillosis (IA), disseminated candidiasis (DC), systemic candidiasis, oropharyngeal infection (OPC), vulvovaginal infection (VVC), allergic bronchopulmonary aspergillosis (ABPA), aspergilloma or chronic pulmonary aspergillosis, aspergillus sinusitis, invasive aspergillosis, etc. Optionally, the detection method further includes diagnosing the subject as suffering from the infection. Optionally, the detection methods of the invention further include evaluating the subject for clinical symptoms of infection. Optionally, the detection methods of the invention further include administering a treatment appropriate for the infection (e.g., with an antifungal agent). The detection methods of the invention may be used to monitor an infection and to predict the subject&#39;s responsiveness to treatment based on the profile of  Candida  or  Aspergillus  nucleic acids/polypeptides detected in a biological sample from the subject (such as whole blood, serum, plasma, aspirate, saliva, urine, discharge, etc.). 
     Typically, the antibody-based assays can be considered to be of four general types: direct binding assays, sandwich assays, competition assays, and displacement assays. In a direct binding assay, either the antibody or antigen is labeled, and there is a means of measuring the number of complexes formed. In a sandwich assay, the formation of a complex of at least three components (e.g., antibody-antigen-antibody) is measured. In a competition assay, labeled antigen and unlabelled antigen compete for binding to the antibody, and either the bound or the free component is measured. In a displacement assay, the labeled antigen is pre-bound to the antibody, and a change in signal is measured as the unlabelled antigen displaces the bound, labeled antigen from the receptor. 
     Lateral flow assays can be conducted according to the teachings of U.S. Pat. No. 5,712,170 and the references cited therein. U.S. Pat. No. 5,712,170 and the references cited therein are hereby incorporated by reference in their entireties. Displacement assays and flow immunosensors useful for carrying out displacement assays are described in: (1) Kusterbeck et al., “Antibody-Based Biosensor for Continuous Monitoring”, in Biosensor Technology, R. P. Buck et al., eds., Marcel Dekker, N.Y. pp. 345-350 (1990); Kusterbeck et al., “A Continuous Flow Immunoassay for Rapid and Sensitive Detection of Small Molecules”, Journal of Immunological Methods, vol. 135, pp. 191-197 (1990); Ligler et al., “Drug Detection Using the Flow Immunosensor”, in Biosensor Design and Application, J. Findley et al., eds., American Chemical Society Press, pp. 73-80 (1992); and Ogert et al., “Detection of Cocaine Using the Flow Immunosensor”, Analytical Letters, vol. 25, pp. 1999-2019 (1992), all of which are incorporated herein by reference in their entireties. Displacement assays and flow immunosensors are also described in U.S. Pat. No. 5,183,740, which is also incorporated herein by reference in its entirety. The displacement immunoassay, unlike most of the competitive immunoassays used to detect small molecules, can generate a positive signal with increasing antigen concentration. One aspect of the invention allows for the exclusion of Western blots as a diagnostic assay, particularly where the Western blot is a screen of whole cell lysates of  Candida  and/or  Aspergillus , or related organisms, against immune serum of infected individuals. In another aspect of the invention, peptide, or polypeptide, based diagnostic assays utilize  Candida  and/or  Aspergillus  polypeptides that have been produced either by chemical peptide synthesis or by recombinant methodologies. 
     The subject invention also provides methods of binding an antibody to a polypeptide of the subject invention comprising contacting a sample containing an antibody with a polypeptide under conditions that allow for the formation of an antibody-antigen complex. These methods can further comprise the step of detecting the formation of said antibody-antigen complex. In various aspects of this method, an immunoassay is conducted for the detection of  Candida  and/or  Aspergillus . Non-limiting examples of such immunoassays include enzyme linked immunosorbent assays (ELISAs), radioimmunoassays (RIAs), lateral flow assays, immunochromatographic strip assays, automated flow assays, Western blots, immunoprecipitation assays, reversible flow chromatographic binding assays, agglutination assays, and biosensors. Additional aspects of the invention provide for the use of an array of polypeptides when conducted the aforementioned methods of detection (the array can comprise polypeptides of the same or different sequence as well as polypeptides from one or more other organisms. 
     The subject invention also concerns antibodies that bind to polypeptides of the invention. Antibodies that are immunospecific for the polypeptides as set forth herein are specifically contemplated. In various embodiments, antibodies that do not cross-react with other proteins are also specifically contemplated. The antibodies of the subject invention can be prepared using standard materials and methods known in the art (see, for example,  Monoclonal Antibodies: Principles and Practice,  1983;  Monoclonal Hybridoma Antibodies: Techniques and Applications,  1982;  Selected Methods in Cellular Immunology,  1980;  Immunological Methods, Vol. II,  1981;  Practical Immunology,  and Kohler et al. [1975]  Nature  256:495). These antibodies can further comprise one or more additional components, such as a solid support, a carrier or pharmaceutically acceptable excipient, or a label. 
     The term “antibody” is used in the broadest sense and specifically covers monoclonal antibodies (including full length monoclonal antibodies), polyclonal antibodies, multispecific antibodies (e.g., bispecific antibodies), and antibody fragments so long as they exhibit the desired biological activity, particularly neutralizing activity. Antibody fragments compromise a portion of a full length antibody, generally the antigen binding or variable region thereof. Examples of antibody fragments include Fab, Fab′, F(ab′) 2 , and Fv fragments; diabodies; linear antibodies; single-chain antibody molecules; and multi-specific antibodies formed from antibody fragments. 
     The term monoclonal antibody as used herein refers to an antibody obtained from a population of substantially homogeneous antibodies, i.e., the individual antibodies comprising the population are identical except for possible naturally occurring mutations that may be present in minor amounts. Monoclonal antibodies are highly specific, being directed against a single antigenic site. Furthermore, in contrast to conventional (polyclonal) antibody preparations that typically include different antibodies directed against different determinants (epitopes), each monoclonal antibody is directed against a single determinant on the antigen. The modifier “monoclonal” indicates the character of the antibody as being obtained from a substantially homogeneous population of antibodies, and is not to be construed as requiring production of the antibody by any particular method. For example, the monoclonal antibodies to be used in accordance with the present invention may be made by the hybridoma method first described by Kohler et al. [1975]  Nature  256: 495, or may be made by recombinant DNA methods (see, e.g., U.S. Pat. No. 4,816,567). The monoclonal antibodies may also be isolated from phage antibody libraries using the techniques described in Clackson et al. [1991]  Nature  352: 624-628 and Marks et al. [1991]  J. Mol. Biol.  222: 581-597, for example. 
     The monoclonal antibodies described herein specifically include “chimeric” antibodies (immunoglobulins) in which a portion of the heavy and/or light chain is identical with or homologous to corresponding sequences in antibodies derived from a particular species or belonging to a particular antibody class or subclass, while the remainder of the chain(s) is identical with or homologous to corresponding sequences in antibodies derived from another species or belonging to another antibody class or subclass, as well as fragments of such antibodies, so long as they exhibit the desired biological activity (U.S. Pat. No. 4,816,567; and Morrison et al. [1984]  Proc. Natl. Acad Sci. USA  81: 6851-6855). Also included are humanized antibodies, such as those taught in U.S. Pat. Nos. 6,407,213 or 6,417,337 which are hereby incorporated by reference in their entirety. 
     “Single-chain Fv” or “sFv” antibody fragments comprise the V H  and V L  domains of an antibody, wherein these domains are present in a single polypeptide chain. Generally, the Fv polypeptide further comprises a polypeptide linker between the V H  and V L  domains which enables the sFv to form the desired structure for antigen binding. For a review of sFv see Pluckthun in The Pharmacology of Monoclonal Antibodies [1994] Vol. 113:269-315, Rosenburg and Moore eds. Springer-Verlag, New York. 
     The term diabodies refers to small antibody fragments with two antigen-binding sites, which fragments comprise a heavy chain variable domain (V H ) connected to a light chain variable domain (V L ) in the same polypeptide chain (V H -V L ). Diabodies are described more fully in, for example, EP 404,097; WO 93/11161; and Hollinger et al. [1993]  Proc. Natl. Acad. Sci. USA  90: 6444-6448. The term linear antibodies refers to the antibodies described in Zapata et al. [1995]  Protein Eng.  8(10):1057-1062. 
     An isolated antibody is one which has been identified and separated and/or recovered from a component of its natural environment. Contaminant components of its natural environment are materials which would interfere with diagnostic or therapeutic uses for the antibody, and may include enzymes, hormones, and other proteinaceous or nonproteinaceous solutes. In preferred embodiments, the antibody will be purified (1) to greater than 95% by weight of antibody as determined by the Lowry method, and most preferably more than 99% by weight, (2) to a degree sufficient to obtain at least 15 residues of N-terminal or internal amino acid sequence by use of a spinning cup sequenator, or (3) to homogeneity by SDS-PAGE under reducing or nonreducing conditions using Coomassie blue or, preferably, silver stain. Isolated antibody includes the antibody in situ within recombinant cells since at least one component of the antibody&#39;s natural environment will not be present. Ordinarily, however, isolated antibody will be prepared by at least one purification step. 
     The terms “comprising”, “consisting of and “consisting essentially of are defined according to their standard meaning. The terms may be substituted for one another throughout the instant application in order to attach the specific meaning associated with each term. The phrases “isolated” or “biologically pure” refer to material that is substantially or essentially free from components which normally accompany the material as it is found in its native state. Thus, isolated peptides in accordance with the invention preferably do not contain materials normally associated with the peptides in their in situ environment. “Link” or “join” refers to any method known in the art for functionally connecting peptides, including, without limitation, recombinant fusion, covalent bonding, disulfide bonding, ionic bonding, hydrogen bonding, and electrostatic bonding. 
     The subject invention also provides isolated, recombinant, and/or purified polynucleotide sequences comprising: 
     a) a polynucleotide sequence encoding a polypeptide as set forth in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein; 
     b) a polynucleotide sequence having at least about 20% to 99.99% identity to a polynucleotide sequence encoding a polypeptide set forth in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein, wherein said polynucleotide encodes a polypeptide having at least one of the activities of the native polypeptide; 
     c) a polynucleotide sequence (a coding sequence) set forth in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein; 
     d) a polynucleotide sequence having at least about 20% to 99.99% identity to the polynucleotide sequence of (a), (b), or (c); 
     e) a polynucleotide that is complementary to the polynucleotides set forth in (a), (b), (c), or (d); 
     f) a genetic construct comprising a polynucleotide sequence as set forth in (a), (b), (c), (d), or (e); 
     g) a vector comprising a polynucleotide or genetic construct as set forth in (a), (b), (c), (d), (e), or (f); 
     h) a host cell comprising a vector as set forth in (g); 
     i) a polynucleotide that hybridizes under low, intermediate or high stringency with a polynucleotide sequence as set forth in (a), (b), (c), (d), (e), (f), or (g); or 
     j) a probe comprising a polynucleotide according to (a), (b), (c), (d), (e), (f), or (g) and, optionally, a label or marker. 
     In one embodiment of each of the aforementioned aspects of the invention a)-n), the one or more polynucleotides (e.g., one, two, three, four, five, or six or more polynucleotides) is among those disclosed Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, or 17 herein. In another embodiment, the one or more polynucleotides (e.g., one, two, three, four, five, or six or more polynucleotides) are from  C. albicans  and selected from the group consisting of Set1p, Rbt4p, Met6p, BGl2p, Gap1, Bgl2, Car1, Enol1, Fba1, IPF9162, PGK1, and Muc1. In another embodiment, the one or more polynucleotides (e.g., one, two, three, or four polynucleotides) are from  C. albicans  and selected from the group consisting of Set1p, Rbt4p, Met6p, and BGl2p. In another embodiment, the one or more polynucleotides (e.g., one, two, three, four, or five polynucleotides) are from  C. albicans  and selected from the group consisting of Set1p, Rbt4p, Met6p, BGl2p, and Gap1. In another embodiment, the one or more polynucleotides (e.g., one, two, three, or four antigens) are from  C. albicans  and selected from the group consisting of Car1, Enol1, Fba1, and IPF9162. In another embodiment, the polynucleotide is from  C. albicans  and is PGK1. In another embodiment, the polynucleotide is from  C. albicans  and is Muc1. 
     In another embodiment, the one or more antigens (e.g., one, two, three, or four or more antigens) are from  C. albicans  and selected from among SET1 (chromatin regulatory protein), ENO1 (enolase I), PGK1-2 (phosphoglycerate kinease), and MUC1-2 (cell surface glycoprotein). In another embodiment, the antigen is from  C. albicans  and is SET1. In another embodiment, the antigen is from  C. albicans  and is ENO1. In another embodiment, the antigen is from  C. albicans  and is PGK1-2. In another embodiment, the antigen is from  C. albicans  and is MUC1-2. 
     The terms “nucleotide sequence”, “polynucleotide” and “nucleic acid” can be used interchangeably and are understood to mean, according to the present invention, either a double-stranded DNA, a single-stranded DNA or products of transcription of the said DNAs (e.g., RNA molecules). It should also be understood that the present invention does not relate to genomic polynucleotide sequences in their natural environment or natural state. The nucleic acid, polynucleotide, or nucleotide sequences of the invention can be isolated, purified (or partially purified), by separation methods including, but not limited to, ion-exchange chromatography, molecular size exclusion chromatography, or by genetic engineering methods such as amplification, subtractive hybridization, cloning, subcloning or chemical synthesis, or combinations of these genetic engineering methods. 
     A homologous polynucleotide or polypeptide sequence, for the purposes of the present invention, encompasses a sequence having a percentage identity with the polynucleotide or polypeptide sequences, set forth herein, of between at least (or at least about) 20.00% to 99.99% (inclusive). The aforementioned range of percent identity is to be taken as including, and providing written description and support for, any fractional percentage, in intervals of 0.01%, between 20.00% and, up to, including 99.99%. These percentages are purely statistical and differences between two nucleic acid sequences can be distributed randomly and over the entire sequence length. For example, homologous sequences can exhibit a percent identity of 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, or 99 percent with the sequences of the instant invention. Typically, the percent identity is calculated with reference to the full length, native, and/or naturally occurring polynucleotide. The terms “identical” or percent “identity”, in the context of two or more polynucleotide or polypeptide sequences, refer to two or more sequences or subsequences that are the same or have a specified percentage of amino acid residues that are the same, when compared and aligned for maximum correspondence over a comparison window, as measured using a sequence comparison algorithm or by manual alignment and visual inspection. 
     Both protein and nucleic acid sequence homologies may be evaluated using any of the variety of sequence comparison algorithms and programs known in the art. Such algorithms and programs include, but are by no means limited to, TBLASTN, BLASTP, FASTA, TFASTA, and CLUSTALW (Pearson and Lipman, 1988,  Proc. Natl. Acad. Sci. USA  85(8):2444-2448; Altschul et al., 1990,  J. Mol. Biol.  215(3):403-410; Thompson et al., 1994,  Nucleic Acids Res.  22(2):4673-4680; Higgins et al., 1996,  Methods Enzymol.  266:383-402; Altschul et al., 1990,  J, Mol. Biol.  215(3):403-410; Altschul et al., 1993,  Nature Genetics  3:266-272). Sequence comparisons are, typically, conducted using default parameters provided by the vendor or using those parameters set forth in the above-identified references, which are hereby incorporated by reference in their entireties. 
     A “complementary” polynucleotide sequence, as used herein, generally refers to a sequence arising from the hydrogen bonding between a particular purine and a particular pyrimidine in double-stranded nucleic acid molecules (DNA-DNA, DNA-RNA, or RNA-RNA). The major specific pairings are guanine with cytosine and adenine with thymine or uracil. A “complementary” polynucleotide sequence may also be referred to as an “antisense” polynucleotide sequence or an “antisense sequence”. 
     Sequence homology and sequence identity can also be determined by hybridization studies under high stringency, intermediate stringency, and/or low stringency. Various degrees of stringency of hybridization can be employed. The more severe the conditions, the greater the complementarity that is required for duplex formation. Severity of conditions can be controlled by temperature, probe concentration, probe length, ionic strength, time, and the like. Preferably, hybridization is conducted under low, intermediate, or high stringency conditions by techniques well known in the art, as described, for example, in Keller, G. H., M. M. Manak [1987]  DNA Probes , Stockton Press, New York, N.Y., pp. 169-170. 
     For example, hybridization of immobilized DNA on Southern blots with  32 P-labeled gene-specific probes can be performed by standard methods (Maniatis et al. [1982]  Molecular Cloning: A Laboratory Manual,  Cold Spring Harbor Laboratory, New York). In general, hybridization and subsequent washes can be carried out under intermediate to high stringency conditions that allow for detection of target sequences with homology to the exemplified polynucleotide sequence. For double-stranded DNA gene probes, hybridization can be carried out overnight at 20-25° C. below the melting temperature (T m ) of the DNA hybrid in 6× SSPE, 5× Denhardt&#39;s solution, 0.1% SDS, 0.1 mg/ml denatured DNA. The melting temperature is described by the following formula (Beltz et al. [1983]  Methods of Enzymology , R. Wu, L. Grossman and K. Moldave [eds.] Academic Press, New York 100:266-285). 
     Tm=81.5° C+16.6 Log[Na + ]0.41 (% G+C)-0.61 (% formamide)-600/length of duplex in base pairs. 
     Washes are typically carried out as follows: 
     (1) twice at room temperature for 15 minutes in 1× SSPE, 0.1% SDS (low stringency wash); 
     (2) once at T m −20° C. for 15 minutes in 0.2× SSPE, 0.1% SDS (intermediate stringency wash). 
     For oligonucleotide probes, hybridization can be carried out overnight at 10-20° C. below the melting temperature (T m ) of the hybrid in 6× SSPE, 5× Denhardt&#39;s solution, 0.1% SDS, 0.1 mg/ml denatured DNA. T m  for oligonucleotide probes can be determined by the following formula: 
         T   m (° C.)=2(number  T/A  base pairs) + 4(number  G/C  base pairs) (Suggs et al. [1981]  ICN - UCLA Symp. Dev. Biol. Using Purified Genes,  D. D. Brown [ed.], Academic Press, New York, 23:683-693). 
     Washes can be carried out as follows: 
     (1) twice at room temperature for 15 minutes 1× SSPE, 0.1% SDS (low stringency wash); 
     (2) once at the hybridization temperature for 15 minutes in 1× SSPE, 0.1% SDS (intermediate stringency wash). 
     In general, salt and/or temperature can be altered to change stringency. With a labeled DNA fragment &gt;70 or so bases in length, the following conditions can be used:
     Low: 1 or 2× SSPE, room temperature   Low: 1 or 2× SSPE, 42° C.   Intermediate: 0.2× or 1× SSPE, 65° C.   High: 0.1× SSPE, 65° C.   

     By way of another non-limiting example, procedures using conditions of high stringency can also be performed as follows: Pre-hybridization of filters containing DNA is carried out for 8 hours to overnight at 65° C. in buffer composed of 6× SSC, 50 mM Tris-HCl (pH 7.5), 1 mM EDTA, 0.02% PVP, 0.02% Ficoll, 0.02% BSA, and 500 μg/ml denatured salmon sperm DNA. Filters are hybridized for 48 hours at 65° C., the preferred hybridization temperature, in pre-hybridization mixture containing 100 μg/ml denatured salmon sperm DNA and 5-20×10 6  cpm of  32 P-labeled probe. Alternatively, the hybridization step can be performed at 65° C. in the presence of SSC buffer, 1× SSC corresponding to 0.15M NaCl and 0.05 M Na citrate. Subsequently, filter washes can be done at 37° C. for 1 hour in a solution containing 2× SSC, 0.01% PVP, 0.01% Ficoll, and 0.01% BSA, followed by a wash in 0.1× SSC at 50° C. for 45 minutes. Alternatively, filter washes can be performed in a solution containing 2× SSC and 0.1% SDS, or 0.5× SSC and 0.1% SDS, or 0.1× SSC and 0.1% SDS at 68° C. for 15 minute intervals. Following the wash steps, the hybridized probes are detectable by autoradiography. Other conditions of high stringency which may be used are well known in the art and as cited in Sambrook et al., 1989, Molecular Cloning, A Laboratory Manual, Second Edition, Cold Spring Harbor Press, N.Y., pp. 9.47-9.57; and Ausubel et al., 1989, Current Protocols in Molecular Biology, Green Publishing Associates and Wiley Interscience, N.Y. are incorporated herein in their entirety. 
     Another non-limiting example of procedures using conditions of intermediate stringency are as follows: Filters containing DNA are pre-hybridized, and then hybridized at a temperature of 60° C. in the presence of a 5× SSC buffer and labeled probe. Subsequently, filters washes are performed in a solution containing 2× SSC at 50° C. and the hybridized probes are detectable by autoradiography. Other conditions of intermediate stringency which may be used are well known in the art and as cited in Sambrook et al., 1989, Molecular Cloning, A Laboratory Manual, Second Edition, Cold Spring Harbor Press, N.Y., pp. 9.47-9.57; and Ausubel et al., 1989, Current Protocols in Molecular Biology, Green Publishing Associates and Wiley Interscience, N.Y. are incorporated herein in their entirety. 
     Duplex formation and stability depend on substantial complementarity between the two strands of a hybrid and, as noted above, a certain degree of mismatch can be tolerated. Therefore, the probe sequences of the subject invention include mutations (both single and multiple), deletions, insertions of the described sequences, and combinations thereof, wherein said mutations, insertions and deletions permit formation of stable hybrids with the target polynucleotide of interest. Mutations, insertions and deletions can be produced in a given polynucleotide sequence in many ways, and these methods are known to an ordinarily skilled artisan. Other methods may become known in the future. 
     It is also well known in the art that restriction enzymes can be used to obtain functional fragments of the subject DNA sequences. For example, Bal31 exonuclease can be conveniently used for time-controlled limited digestion of DNA (commonly referred to as “erase-a-base” procedures). See, for example, Maniatis et al. [1982]  Molecular Cloning: A Laboratory Manual,  Cold Spring Harbor Laboratory, New York; Wei et al. [1983]  J. Biol. Chem.  258:13006-13512. 
     The present invention further comprises fragments of the polynucleotide sequences of the instant invention. Representative fragments of the polynucleotide sequences according to the invention will be understood to mean any nucleotide fragment having at least 5 successive nucleotides, preferably at least 12 successive nucleotides, and still more preferably at least 15, 18, or at least 20 successive nucleotides of the sequence from which it is derived. The upper limit for such fragments is the total number of nucleotides found in the full-length sequence encoding a particular polypeptide. The term “successive” can be interchanged with the term “consecutive” or the phrase “contiguous span”. Thus, in some embodiments, a polynucleotide fragment may be referred to as “a contiguous span of at least X nucleotides, wherein X is any integer value beginning with 5; the upper limit for such fragments is one nucleotide less than the total number of nucleotides found in the full-length sequence encoding a particular polypeptide. 
     In some embodiments, the subject invention includes those fragments capable of hybridizing under various conditions of stringency conditions (e.g., high or intermediate or low stringency) with a nucleotide sequence according to the invention; fragments that hybridize with a nucleotide sequence of the subject invention can be, optionally, labeled as set forth below. 
     The subject invention provides, in one embodiment, methods for the identification of the presence of nucleic acids according to the subject invention in transformed host cells or in cells isolated from an individual suspected of being infected by  Candida  and/or  Aspergillus . In these varied embodiments, the invention provides for the detection of nucleic acids in a sample (obtained from the individual or from a cell culture) comprising contacting a sample with a nucleic acid (polynucleotide) of the subject invention (such as an RNA, mRNA, DNA, cDNA, or other nucleic acid). In a preferred embodiment, the polynucleotide is a probe that is, optionally, labeled and used in the detection system. Many methods for detection of nucleic acids exist and any suitable method for detection is encompassed by the instant invention. Typical assay formats utilizing nucleic acid hybridization include, and are not limited to, 1) nuclear run-on assay, 2) slot blot assay, 3) northern blot assay (Alwine, et al.,  Proc. Natl. Acad. Sci.  74:5350), 4) magnetic particle separation, 5) nucleic acid or DNA chips, 6) reverse Northern blot assay, 7) dot blot assay, 8) in situ hybridization, 9) RNase protection assay (Melton, et al.,  Nuc. Acids Res.  12:7035 and as described in the 1998 catalog of Ambion, Inc., Austin, Tex.), 10) ligase chain reaction, 11) polymerase chain reaction (PCR), 12) reverse transcriptase (RT)-PCR (Berchtold, et al.,  Nuc. Acids. Res.  17:453), 13) differential display RT-PCR (DDRT-PCR) or other suitable combinations of techniques and assays. Labels suitable for use in these detection methodologies include, and are not limited to 1) radioactive labels, 2) enzyme labels, 3) chemiluminescent labels, 4) fluorescent labels, 5) magnetic labels, or other suitable labels, including those set forth below. These methodologies and labels are well known in the art and widely available to the skilled artisan. Likewise, methods of incorporating labels into the nucleic acids are also well known to the skilled artisan. 
     Thus, the subject invention also provides detection probes (e.g., fragments of the disclosed polynucleotide sequences) for hybridization with a target sequence or the amplicon generated from the target sequence. Such a detection probe will comprise a contiguous/consecutive span of at least 8, 9, 10, 11, 12, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 95, or 100 nucleotides. Labeled probes or primers are labeled with a radioactive compound or with another type of label as set forth above (e.g., 1) radioactive labels, 2) enzyme labels, 3) chemiluminescent labels, 4) fluorescent labels, or 5) magnetic labels). Alternatively, non-labeled nucleotide sequences may be used directly as probes or primers; however, the sequences are generally labeled with a radioactive element ( 32 P,  35 S,  3 H,  125 I) or with a molecule such as biotin, acetylaminofluorene, digoxigenin, 5-bromo-deoxyuridine, or fluorescein to provide probes that can be used in numerous applications. 
     Polynucleotides of the subject invention can also be used for the qualitative and quantitative analysis of gene expression using arrays or polynucleotides that are attached to a solid support. As used herein, the term array means a one-, two-, or multi-dimensional arrangement of full length polynucleotides or polynucleotides of sufficient length to permit specific detection of gene expression. Preferably, the fragments are at least 15 nucleotides in length. More preferably, the fragments are at least 100 nucleotides in length. More preferably, the fragments are more than 100 nucleotides in length. In some embodiments the fragments may be more than 500 nucleotides in length. 
     For example, quantitative analysis of gene expression may be performed with full-length polynucleotides of the subject invention, or fragments thereof, in a complementary DNA microarray as described by Schena et al. (Science 270:467-470, 1995;  Proc. Natl. Acad. Sci. U.S.A.  93:10614-10619, 1996). Polynucleotides, or fragments thereof, are amplified by PCR and arrayed onto silylated microscope slides. Printed arrays are incubated in a humid chamber to allow rehydration of the array elements and rinsed, once in 0.2% SDS for 1 minute, twice in water for 1 minute and once for 5 minutes in sodium borohydride solution. The arrays are submerged in water for 2 minutes at 95° C., transferred into 0.2% SDS for 1 minute, rinsed twice with water, air dried and stored in the dark at 25° C. 
     mRNA is isolated from a biological sample and probes are prepared by a single round of reverse transcription. Probes are hybridized to 1 cm 2  microarrays under a 14×14 mm glass coverslip for 6-12 hours at 60° C. Arrays are washed for 5 minutes at 25° C. in low stringency wash buffer (1× SSC/0.2% SDS), then for 10 minutes at room temperature in high stringency wash buffer (0.1× SSC/0.2% SDS). Arrays are scanned in 0.1× SSC using a fluorescence laser scanning device fitted with a custom filter set. Accurate differential expression measurements are obtained by taking the average of the ratios of two independent hybridizations. 
     Quantitative analysis of the polynucleotides present in a biological sample can also be performed in complementary DNA arrays as described by Pietu et al. (Genome Research 6:492-503, 1996). The polynucleotides of the invention, or fragments thereof, are PCR amplified and spotted on membranes. Then, mRNAs originating from biological samples derived from various tissues or cells are labeled with radioactive nucleotides. After hybridization and washing in controlled conditions, the hybridized mRNAs are detected by phospho-imaging or autoradiography. Duplicate experiments are performed and a quantitative analysis of differentially expressed mRNAs is then performed. 
     Alternatively, the polynucleotide sequences of to the invention may also be used in analytical systems, such as DNA chips. DNA chips and their uses are well known in the art and (see for example, U.S. Pat. Nos. 5,561,071; 5,753,439; 6,214,545; Schena et al.,  BioEssays,  1996, 18:427-431; Bianchi et al.,  Clin. Diagn. Virol.,  1997, 8:199-208; each of which is hereby incorporated by reference in their entireties) and/or are provided by commercial vendors such as Affymetrix, Inc. (Santa Clara, Calif.). In addition, the nucleic acid sequences of the subject invention can be used as molecular weight markers in nucleic acid analysis procedures. 
     The subject invention also provides for modified nucleotide sequences. Modified nucleic acid sequences will be understood to mean any nucleotide sequence that has been modified, according to techniques well known to persons skilled in the art, and exhibiting modifications in relation to the native, naturally occurring nucleotide sequences. 
     The subject invention also provides genetic constructs comprising: a) a polynucleotide sequence encoding a polypeptide set forth in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein, or a fragment thereof; b) a polynucleotide sequence having at least about 20% to 99.99% identity to a polynucleotide sequence encoding a native polypeptide, or a fragment of the native polypeptide, wherein the polynucleotide encodes a polypeptide having at least one of the activities or a polypeptide of the native full length polypeptide, or a fragment thereof; c) a polynucleotide sequence encoding a fragment of a polypeptide listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein, wherein said fragment has at least one of the activities of the polypeptide; d) a polynucleotide sequence listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16 or 17 disclosed herein; e) a polynucleotide sequence having at least about 20% to 99.99% identity to the polynucleotide sequence listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, or 17; f) a polynucleotide sequence encoding a fragment of a variant polypeptide as set forth in (e); g) a polynucleotide sequence encoding a multimeric construct; or h) a polynucleotide that is complementary to the polynucleotides set forth in (a), (b), (c), (d), (e), (f), or (g). Genetic constructs of the subject invention can also contain additional regulatory elements such as promoters and enhancers and, optionally, selectable markers. 
     Also within the scope of the subject instant invention are vectors or expression cassettes containing genetic constructs as set forth herein or polynucleotides encoding the polypeptides, set forth supra, operably linked to regulatory elements. The vectors and expression cassettes may contain additional transcriptional control sequences as well. The vectors and expression cassettes may further comprise selectable markers. The expression cassette may contain at least one additional gene, operably linked to control elements, to be co-transformed into the organism. Alternatively, the additional gene(s) and control element(s) can be provided on multiple expression cassettes. Such expression cassettes are provided with a plurality of restriction sites for insertion of the sequences of the invention to be under the transcriptional regulation of the regulatory regions. The expression cassette(s) may additionally contain selectable marker genes operably linked to control elements. 
     The expression cassette will include in the 5′-3′ direction of transcription, a transcriptional and translational initiation region, a DNA sequence of the invention, and a transcriptional and translational termination regions. The transcriptional initiation region, the promoter, may be native or analogous, or foreign or heterologous, to the host cell. Additionally, the promoter may be the natural sequence or alternatively a synthetic sequence. By “foreign” is intended that the transcriptional initiation region is not found in the native plant into which the transcriptional initiation region is introduced. As used herein, a chimeric gene comprises a coding sequence operably linked to a transcriptional initiation region that is heterologous to the coding sequence. 
     Another aspect of the invention provides vectors for the cloning and/or the expression of a polynucleotide sequence taught herein. Vectors of this invention, including vaccine vectors, can also comprise elements necessary to allow the expression and/or the secretion of the said nucleotide sequences in a given host cell. The vector can contain a promoter, signals for initiation and for termination of translation, as well as appropriate regions for regulation of transcription. In certain embodiments, the vectors can be stably maintained in the host cell and can, optionally, contain signal sequences directing the secretion of translated protein. These different elements are chosen according to the host cell used. Vectors can integrate into the host genome or, optionally, be autonomously-replicating vectors. 
     The subject invention also provides for the expression of a polypeptide, peptide, fragment, or variant encoded by a polynucleotide sequence disclosed herein comprising the culture of a host cell transformed with a polynucleotide of the subject invention under conditions that allow for the expression of the polypeptide and, optionally, recovering the expressed polypeptide. 
     The disclosed polynucleotide sequences can also be regulated by a second nucleic acid sequence so that the protein or peptide is expressed in a host transformed with the recombinant DNA molecule. For example, expression of a protein or peptide may be controlled by any promoter/enhancer element known in the art. Promoters which may be used to control expression include, but are not limited to, the CMV-IE promoter, the SV40 early promoter region (Bernoist and Chambon  Nature,  1981, 290:304-310), the promoter contained in the 3′ long terminal repeat of Rous sarcoma virus (Yamamoto et al., 1980,  Cell  22:787-797), the herpes simplex thymidine kinase promoter (Wagner et al., 1981,  Proc. Natl. Acad. Sci. U.S.A.  78:1441-1445), the regulatory sequences of the metallothionein gene (Brinster et al., 1982,  Nature  296:39-42); prokaryotic vectors containing promoters such as the β-lactamase promoter (Villa-Kamaroff et al., 1978,  Proc. Natl. Acad. Sci. U.S.A.  75:3727-3731), or the tac promoter (DeBoer et al., 1983,  Proc. Natl. Acad. Sci. U.S.A.  80:21-25); see also “Useful proteins from recombinant bacteria” in Scientific American, 1980, 242:74-94; plant expression vectors comprising the nopaline synthetase promoter region (Herrera-Estrella et al., 1983,  Nature  303:209-213) or the cauliflower mosaic virus 35S RNA promoter (Gardner et al., 1981,  Nucl. Acids Res.  9:2871), and the promoter of the photosynthetic enzyme ribulose biphosphate carboxylase (Herrera-Estrella et al., 1984, Nature 310:115-120); promoter elements from yeast or fungi such as the Gal 4 promoter, the ADC (alcohol dehydrogenase) promoter, PGK (phosphoglycerol kinase) promoter, and/or the alkaline phosphatase promoter. 
     The vectors according to the invention are, for example, vectors of plasmid or viral origin. In a specific embodiment, a vector is used that comprises a promoter operably linked to a protein or peptide-encoding nucleic acid sequence contained within the disclosed polynucleotide sequences, one or more origins of replication, and, optionally, one or more selectable markers (e.g., an antibiotic resistance gene). Expression vectors comprise regulatory sequences that control gene expression, including gene expression in a desired host cell. Exemplary vectors for the expression of the polypeptides of the invention include the pET-type plasmid vectors (Promega) or pBAD plasmid vectors (Invitrogen) or those provided in the examples below. Furthermore, the vectors according to the invention are useful for transforming host cells so as to clone or express the polynucleotide sequences of the invention. 
     The invention also encompasses the host cells transformed by a vector according to the invention. These cells may be obtained by introducing into host cells a nucleotide sequence inserted into a vector as defined above, and then culturing the said cells under conditions allowing the replication and/or the expression of the polynucleotide sequences of the subject invention. 
     The host cell may be chosen from eukaryotic or prokaryotic systems, such as for example bacterial cells, (Gram negative or Gram positive), yeast cells (for example,  Saccharomyces cereviseae  or  Pichia pastoris ), animal cells (such as Chinese hamster ovary (CHO) cells), plant cells, and/or insect cells using baculovirus vectors. In some embodiments, the host cells for expression of the polypeptides include, and are not limited to, those taught in U.S. Pat. Nos. 6,319,691, 6,277,375, 5,643,570, or 5,565,335, each of which is incorporated by reference in its entirety, including all references cited within each respective patent. 
     Furthermore, a host cell strain may be chosen which modulates the expression of the inserted sequences, or modifies and processes the gene product in the specific fashion desired. Expression from certain promoters can be elevated in the presence of certain inducers; thus, expression of the genetically engineered polypeptide may be controlled. Furthermore, different host cells have characteristic and specific mechanisms for the translational and post-translational processing and modification (e.g., glycosylation, phosphorylation) of proteins. Appropriate cell lines or host systems can be chosen to ensure the desired modification and processing of the foreign protein expressed. For example, expression in a bacterial system can be used to produce an unglycosylated core protein product. Expression in yeast will produce a glycosylated product. Expression in mammalian cells can be used to ensure “native” glycosylation of a heterologous protein. Furthermore, different vector/host expression systems may effect processing reactions to different extents. 
     The subject invention also concerns novel compositions that can be employed to elicit an immune response or a protective immune response. In this aspect of the invention, an amount of a composition comprising recombinant DNA or mRNA encoding a polynucleotide of the subject invention sufficient to elicit an immune response or protective immune response is administered to an individual. Signal sequences may be deleted from the nucleic acid encoding an antigen of interest and the individual may be monitored for the induction of an immune response according to methods known in the art. A “protective immune response” or “therapeutic immune response” refers to a CTL (or CD8 +  T cell) and/or an HTL (or CD4 30   T cell) response to an antigen that, in some way, prevents or at least partially arrests disease symptoms, side effects or progression. The immune response may also include an antibody response that has been facilitated by the stimulation of helper T cells. 
     In another embodiment, the subject invention further comprises the administration of polynucleotide vaccines in conjunction with a polypeptide antigen, or composition thereof, of the invention. In a preferred embodiment, the antigen is the polypeptide that is encoded by the polynucleotide administered as the polynucleotide vaccine. As a particularly preferred embodiment, the polypeptide antigen is administered as a booster subsequent to the initial administration of the polynucleotide vaccine. 
     A further embodiment of the subject invention provides for the induction of an immune response to the  Candida  and/or  Aspergillus  antigens disclosed herein using a “prime-boost” vaccination regimen known to those skilled in the art. In this aspect of the invention, a DNA vaccine or polypeptide antigen of the subject invention is administered to a subject in an amount sufficient to “prime” the immune response of the subject. The immune response of the subject is then “boosted” via the administration of: 1) one or a combination of: a peptide, polypeptide, and/or full length polypeptide antigen of the subject invention (optionally in conjunction with a immunostimulatory molecule and/or an adjuvant); or 2) a viral vector that contains nucleic acid encoding one, or more, of the same or, optionally, different, antigens, multi-epitope constructs, and/or peptide antigens set forth herein. In some alternative embodiments of the invention, a gene encoding an immunostimulatory molecule may be incorporated into the viral vector used to “boost the immune response of the individual. Exemplary immunostimulatory molecules include, and are not limited to, IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-11, IL-15, Il-16, Il-18, IL-23, IL-24, erythropoietin, G-CSF, M-CSF, platelet derived growth factor (PDGF), MSF, FLT-3 ligand, EGF, fibroblast growth factor (FGF; e.g., aFGF (FGF-1)), bFGF (FGF-2), FGF-3, FGF-4, FGF-5, FGF-6, or FGF-7), insulin-like growth factors (e.g., IGF-1, IGF-2); vascular endothelial growth factor (VEGF); interferons (e.g., IFN-γ, IFN-α, IFN-β); leukemia inhibitory factor (LIF); ciliary neurotrophic factor (CNTF); oncostatin M; stem cell factor (SCF); transforming growth factors (e.g., TGF-a, TGF-β1, TGF-β1, TGF-β1), or chemokines (such as, but not limited to, BCA-1/BLC-1, BRAK/Kec, CXCL16, CXCR3, ENA-78/LIX, Eotaxin-1, Eotaxin-2/MPIF-2, Exodus-2/SLC, Fractalkine/Neurotactin, GROalpha/MGSA, HCC-1, 1-TAC, Lymphotactin/ATAC/SCM, MCP-1/MCAF, MCP-3, MCP-4, MDC/STCP-1, ABCD-1, MIP-1α, MIP-1β, MIP-2α/GROβ, MIP-3α/Exodus/LARC, MIP-3β/Exodus-3/ELC, MIP-4/PARC/DC-CK1, PF-4, RANTES, SDF1α, TARC, or TECK). Genes encoding these immunostimulatory molecules are known to those skilled in the art and coding sequences may be obtained from a variety of sources, including various patents databases, publicly available databases (such as the nucleic acid and protein databases found at the National Library of Medicine or the European Molecular Biology Laboratory), the scientific literature, or scientific literature cited in catalogs produced by companies such as Genzyme, Inc., R&amp;D Systems, Inc, or InvivoGen, Inc. [see, for example, the 1995 Cytokine Research Products catalog, Genzyme Diagnostics, Genzyme Corporation, Cambridge Mass.; 2002 or 1995 Catalog of R&amp;D Systems, Inc (Minneapolis, Minn.); or 2002 Catalog of InvivoGen, Inc (San Diego, Calif.) each of which is incorporated by reference in its entirety, including all references cited therein]. 
     Methods of introducing DNA vaccines into individuals are well-known to the skilled artisan. For example, DNA can be injected into skeletal muscle or other somatic tissues (e.g., intramuscular injection). Cationic liposomes or biolistic devices, such as a gene gun, can be used to deliver DNA vaccines. Alternatively, iontophoresis and other means for transdermal transmission can be used for the introduction of DNA vaccines into an individual. 
     Viral vectors for use in the subject invention can have a portion of the viral genome is deleted to introduce new genes without destroying infectivity of the virus. The viral vector of the present invention is, typically, a non-pathogenic virus. At the option of the practitioner, the viral vector can be selected so as to infect a specific cell type, such as professional antigen presenting cells (e.g., macrophage or dendritic cells). Alternatively, a viral vector can be selected that is able to infect any cell in the individual. Exemplary viral vectors suitable for use in the present invention include, but are not limited to poxvirus such as vaccinia virus, avipox virus, fowlpox virus, a highly attenuated vaccinia virus (such as Ankara or MVA [Modified Vaccinia Ankara]), retrovirus, adenovirus, baculovirus and the like. In a preferred embodiment, the viral vector is Ankara or MVA. 
     General strategies for construction of vaccinia virus expression vectors are known in the art (see, for example, Smith and Moss  Bio Techniques  November/December, 306-312, 1984; U.S. Pat. No. 4,738,846 (hereby incorporated by reference in its entirety). Sutter and Moss ( Proc. Natl. Acad. Sci U.S.A.  89:10847-10851, 1992) and Sutter et al. ( Vaccine,  12(11):1032-40, 1994) disclose the construction and use as a vector, a non-replicating recombinant Ankara virus (MVA) which can be used as a viral vector in the present invention. 
     Compositions comprising the subject polynucleotides can include appropriate nucleic acid vaccine vectors (plasmids), which are commercially available (e.g., Vical, San Diego, Calif.) or other nucleic acid vectors (plasmids), which are also commercially available (e.g., Valenti, Burlingame, Calif.). Alternatively, compositions comprising viral vectors and polynucleotides according to the subject invention are provided by the subject invention. In addition, the compositions can include a pharmaceutically acceptable carrier, e.g., saline. The pharmaceutically acceptable carriers are well known in the art and also are commercially available. For example, such acceptable carriers are described in E. W. Martin&#39;s  Remington&#39;s Pharmaceutical Science,  Mack Publishing Company, Easton, Pa. 
     The subject invention also provides an assay that comprises the use of polynucleotides, as set forth herein, for the detection of  Candida  and/or  Aspergillus . Some aspects of the invention provide for a method that comprises contacting a sample comprising a population of polynucleotides with a second population of polynucleotides under conditions that allow for the formation of an hybridization complex, wherein said second population of polynucleotides comprises polynucleotides that encode at least one polypeptide that is listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein; d) fragments of polynucleotides; e) a polypeptide as set forth in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein; f) a variant polypeptide of such native polypeptide, wherein the variant polypeptide specifically binds to an antibody that specifically binds to a polypeptide listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein; g) a variant polypeptide fragment of those listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein, wherein the variant polypeptide fragment specifically binds to an antibody that specifically binds to a polypeptide disclosed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein or a fragment of those polypeptides; h) a variant of a polypeptide as set forth in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein, wherein the variant polypeptide specifically binds to an antibody that specifically binds to a polypeptide listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein; i) a heterologous polypeptide fused, in frame, to a polypeptide comprising one of those listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein; and j) mixtures of polypeptides as set forth in a), b), c), d), e), 1), g), h), or i). The method can further comprise the step of detecting the hybridization complex and the second population of polynucleotides can be an array of polynucleotides or the same or different sequence if desired. 
     In one embodiment of each of the aforementioned aspects of the invention a)-i), the one or more polypeptides (e.g., one, two, three, four, five, or six or more polypeptides) is among those polypeptides disclosed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 herein, or among those polypeptides encoded by the nucleic acids disclosed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, or 17 herein. In another embodiment, the one or more polypeptides (e.g., one, two, three, four, five, or six or more polypeptides) are from  C. albicans  and selected from the group consisting of Set1p, Rbt4p, Met6p, BGl2p, Gap1, Bgl2, Car1, Enol1, Fba1, IPF9162, PGK1, and Muc1. In another embodiment, the one or more polypeptides (e.g., one, two, three, or four polypeptides) are from  C. albicans  and selected from the group consisting of Set1p, Rbt4p, Met6p, and BGl2p. In another embodiment, the one or more polypeptides (e.g., one, two, three, four, or five polypeptides) are from  C. albicans  and selected from the group consisting of Set1p, Rbt4p, Met6p, BGl2p, and Gap1. In another embodiment, the one or more polypeptides (e.g., one, two, three, or four polypeptides) are from  C. albicans  and selected from the group consisting of Car1, Enol1, Fba1, and 1PF9162. In another embodiment, the polypeptide is from  C. albicans  and is PGK1. In another embodiment, the polypeptide is from  C. albicans  and is Muc1. 
     The terms “comprising”, “consisting of”, and “consisting essentially of are defined according to their standard meaning and may he substituted for one another throughout the instant application in order to attach the specific meaning associated with each term. 
     As used in this specification and the appended claims, the singular forms “a”, “an”, and “the” include plural reference unless the context clearly dictates otherwise. Thus, for example, a reference to “a polypeptide” includes more than one such polypeptide, and the like. Reference to “an antigen” includes more than one such antigen. Reference to “a cell” includes more than one such cell. Reference to “a polynucleotide” includes more than one such polynucleotide. 
     Exemplified Embodiments 
     The invention includes, but is not limited to, the following embodiments:
     Embodiment 1. An isolated, recombinant, or purified polypeptide comprising   

     (a) an amino acid sequence listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein; or 
     (b) fragments of (a); or 
     (c) a polypeptide listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein; or 
     (d) one or more polypeptides (e.g., one, two, three, or four or more polypeptides) selected from among SET1 (chromatin regulatory protein), ENO1 (enolase I), PGK1-2 (phosphoglycerate kinease), and MUC1-2 (cell surface glycoprotein); or 
     (e) one or more polypeptides (e.g., one, two, three, four, five, six, seven, eight, nine, ten, eleven, twelve, thirteen, fourteen, or fifteen or more polypeptides) selected from among METE-1, MET6-2, NOT5, RBT4, IPF9162, CAR1, GAP1, SET1, ENO1, FBA1, PGK1-1, PGK1-2, MUC1-1, MUC1-2, and BGL2; or 
     (f) one or more polypeptides (e.g., one, two, three, four, five, six, or seven or more polypeptides) selected from among SET1, ENO1, FBA1, PGK1-1, PGK1-2, MUC1-2, and BGL2; or 
     (g) a variant of a polypeptide of (a), (b), (c), (d), (e), or (f), wherein said variant polypeptide specifically binds to an antibody that specifically binds to a polypeptide of (a), (b), (c), (d), (e), or (f); or 
     (h) a fragment of a polypeptide of (c), (d), (e), or (f), wherein said fragment specifically binds to an antibody that specifically binds to a polypeptide of (c), (d), (e), or (f), or a fragment of (c), (d), (e), or (f); or 
     (i) a heterologous polypeptide fused, in frame, to a polypeptide comprising the polypeptide of (a), (b), (c), (d), (e), or (f); or 
     (j) a multimeric construct comprising a polypeptide of (a), (b), (c), (d), (e), or (f); or a fragment or variant of (a), (b), (c), (d), (e), (f), (g), (h), or (i).
     Embodiment 2. A composition comprising at least one isolated or purified polypeptide according to embodiment 1, or a isolated polynucleotide encoding the polypeptide; and an additional component.   Embodiment 3. The composition according to embodiment 2, wherein said additional component is a solid support, and wherein said polypeptide or said encoding polynucleotide is immobilized on said support.   Embodiment 4. The composition according to embodiment 3, wherein said solid support is selected from the group consisting of microtiter wells, magnetic beads, non-magnetic beads, agarose beads, glass, cellulose, plastics, polyethylene, polypropylene, polyester, nitrocellulose, nylon, and polysulfone.   Embodiment 5. The composition according to embodiment 2, wherein said additional component is a pharmaceutically acceptable excipient.   Embodiment 6. The composition according to embodiment 3 or 4, wherein said solid support provides an array of polypeptides or encoding polynucleotides, and wherein said array of polypeptides is selected from among the polypeptides listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein, or a fragment or variant thereof.   Embodiment 7. The composition according to any one of embodiments 2-5, wherein said polypeptide is one or more polypeptides (e.g., one, two, three, or four or more antigens) selected from among SET1 (chromatin regulatory protein), ENO1 (enolase I), PGK1-2 (phosphoglycerate kinease), and MUC1-2 (cell surface glycoprotein).   Embodiment 8. The composition according to any one of embodiments 2-5, wherein said polypeptide is one or more polypeptides (e.g., one, two, three, four, five, six, seven, eight, nine, ten, eleven, twelve, thirteen, fourteen, or fifteen or more polypeptides) selected from among METE-1, MET6-2, NOT5, RBT4, IPF9162, CAR1, GAP1, SET1, ENO1, FBA1, PGK1-1, PGK1-2, MUC1-1, MUC1-2, and BGL2.   Embodiment 9. The composition according to any one of embodiments 2-5, wherein said polypeptide is one or more polypeptides (e.g., one, two, three, four, five, six, or seven or more polypeptides) selected from among SET1, ENO1, FBA1, PGK1-1, PGK1-2, MUC1-2, and BGL2.   Embodiment 10. The composition according to any of embodiments 2-9, further comprising an additional antigen of interest.   Embodiment 11. A method of binding an antibody to a polypeptide comprising contacting a sample containing an antibody with a polypeptide under conditions that allow for the formation of an antibody-antigen complex, wherein said polypeptide is selected from the group consisting of the polypeptides listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein, or a fragment or variant thereof, wherein said sample containing an antibody is an adsorbed or nonadsorbed sample.   Embodiment 12. The method according to embodiment 11, wherein said polypeptide is one or more polypeptides (e.g., one, two, three, or four or more antigens) selected from among SET1 (chromatin regulatory protein), ENO1 (enolase I), PGK1-2 (phosphoglycerate kinease), and MUC1-2 (cell surface glycoprotein).   Embodiment 13. The method according to embodiment 11, wherein said polypeptide is one or more polypeptides (e.g., one, two, three, four, five, six, seven, eight, nine, ten, eleven, twelve, thirteen, fourteen, or fifteen or more polypeptides) selected from among MET6-1, MET6-2, NOT5, RBT4, 1PF9162, CAR1, GAP1, SET1, ENO1, FBA1, PGK1-1, PGK1-2, MUC1-1, MUC1-2, and BGL2.   Embodiment 14. The method according to embodiment 11, wherein said polypeptide is one or more polypeptides (e.g., one, two, three, four, five, six, or seven or more polypeptides) selected from among SET1, ENO1, FBA1, PGK1-1 PGK1-2, MUC1-2, and BGL2.   Embodiment 15. The method according to any of embodiments 11-14, further comprising the step of detecting the formation of said antibody-antigen complex.   Embodiment 16. The method according to any of embodiments 11-15, wherein said method is an immunoassay.   Embodiment 17. The method according to embodiment 16, wherein said immunoassay is selected from the group consisting of enzyme linked immunosorbent assays (ELISAs), radioimmunoassays (RIAs), lateral flow assays, immunochromatographic strip assays, automated flow assays, Western blots, immunoprecipitation assays, reversible flow chromatographic binding assays, agglutination assays, and biosensors.   Embodiment 18. The method according to any of embodiments 11-17, wherein said method is performed using an array of polypeptides.   Embodiment 19. The method according to embodiment 18, wherein said array comprises or consists of SET1 (chromatin regulatory protein), ENO1 (enolase I), PGK1-2 (phosphoglycerate kinease), and MUC1-2 (cell surface glycoprotein).   Embodiment 20. The method according to embodiment 18, wherein said array comprises or consists of METE-1, METE-2, NOT5, RBT4, IPF9162, CAR1, GAP1, SET1, ENO1, FBA1, PGK1-1, PGK1-2, MUC1-1, MUC1-2, and BGL2.   Embodiment 21. The method according to embodiment 18, wherein said comprises or consists of SET1, ENO1, FBA1, PGK1-1, PGK1-2, MUC1-2, and BGL2.   Embodiment 22. The method according to embodiment 18, wherein said array of polypeptides comprises the same polypeptide.   Embodiment 23. The method according to any of embodiments 18-21, wherein said array of polypeptides further comprises isolated polypeptides from other organisms of interest.   Embodiment 24. An isolated or purified polynucleotide comprising a nucleic acid sequence encoding a polypeptide of embodiment 1, or a fragment or variant thereof   Embodiment 25. An antibody that specifically binds to a polypeptide of embodiment 1, or a fragment or variant thereof.   Embodiment 26. The antibody according to embodiment 25, further comprising an additional component.   Embodiment 27. The antibody according to embodiment 26, wherein said additional component is a solid support.   Embodiment 28. The antibody according to embodiment 26, wherein said additional component is a carrier.   Embodiment 29. The antibody according to embodiment 28, wherein said carrier is a pharmaceutically acceptable excipient.   Embodiment 30. The antibody according to embodiment 26, wherein said additional component is a label.   Embodiment 31. A host cell comprising a polynucleotide according to embodiment 24.   Embodiment 32. A method of hybridizing polynucleotides comprising contacting a sample comprising a population of polynucleotides with a second population of polynucleotides under conditions that allow for the formation of an hybridization complex, wherein said second population of polynucleotides comprises polynucleotides that encode at least one polypeptide that is selected from among:   

     (a) an amino acid sequence listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein; or 
     (b) a fragment of (a); or 
     (c) a polypeptide listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein; or 
     (d) one or more polypeptides (e.g., one, two, three, or four or more polypeptides) selected from among SET1 (chromatin regulatory protein), ENO1 (enolase I), PGK1-2 (phosphoglycerate kinease), and MUC1-2 (cell surface glycoprotein); or 
     (e) one or more polypeptides (e.g., one, two, three, four, five, six, seven, eight, nine, ten, eleven, twelve, thirteen, fourteen, or fifteen or more polypeptides) selected from among MET6-1, MET6-2, NOT5, RBT4, IPF9162, CAR1, GAP1, SET1, ENO1, FBA1, PGK1-1, PGK1-2, MUC1-1, MUC1-2, and BGL2; or 
     (f) one or more polypeptides (e.g., one, two, three, four, five, six, or seven or more polypeptides) selected from among SET1, ENO1, FBA1, PGK1-1, PGK1-2, MUC1-2, and BGL2; or 
     (g) a variant of a polypeptide of (a), (b), (c), (d), (e), or (f), wherein said variant polypeptide specifically binds to an antibody that specifically binds to a polypeptide of (a), (b), (c), (d), (e), or (f); or 
     (h) a fragment of a polypeptide of (c), (d), (e), or (f), wherein said fragment specifically binds to an antibody that specifically binds to a polypeptide of (c), (d), (e), or (f), or a fragment of (c), (d), (e), or (f); or 
     (i) a heterologous polypeptide fused, in frame, to a polypeptide comprising the polypeptide of (a), (b), (c), (d), (e), (f), (g), or (h); or 
     (j) a multimeric construct comprising a polypeptide of (a), (b), (c), (d), (e), (f), (g), (h), or (i); or a fragment or variant of (c), (d), (c), or (f).
     Embodiment 33. The method according to embodiment 32, further comprising the step of detecting the hybridization complex.   Embodiment 34. The method according to embodiment 32, wherein said second population of polynucleotides is an array of polynucleotides or the same or different sequence.   Embodiment 35. A method of inducing an immune response in a subject, comprising administering an effective amount of:   

     (1) a polypeptide antigen comprising:
         (a) an amino acid sequence listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein; or   (b) a fragment of (a); or   (c) a polypeptide listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17 or 18 disclosed herein; or   (d) one or more polypeptides (e.g., one, two, three, or four or more polypeptides) selected from among SET1 (chromatin regulatory protein), ENO1 (enolase I), PGK1-2 (phosphoglycerate kinease), and MUC1-2 (cell surface glycoprotein); or   (e) one or more polypeptides (e.g., one, two, three, four, five, six, seven, eight, nine, ten, eleven, twelve, thirteen, fourteen, or fifteen or more polypeptides) selected from among MET6-1, MET6-2, NOT5, RBT4, IPF9162, CAR1, GAP1, SET1, ENO1, FBA1, PGK1-1, PGK1-2, MUC1-1, MUC1-2, and BGL2; or   (f) one or more polypeptides (e.g., one, two, three, four, five, six, or seven or more polypeptides) selected from among SET1, ENO1, FBA1, PGK1-1, PGK1-2, MUC1-2, and BGL2; or   (g) a variant of a polypeptide of (a), (b), (c), (d), (e), or (f), wherein said variant polypeptide specifically binds to an antibody that specifically binds to a polypeptide of (a), (b), (c), (d), (e), or (f); or   (h) a fragment of a polypeptide of (c), (d), (e), or (f), wherein said fragment specifically binds to an antibody that specifically binds to a polypeptide of (c), (d), (e), or (1), or a fragment of (c), (d), (e), or (f); or   (i) a heterologous polypeptide fused, in frame, to a polypeptide comprising the polypeptide of (a), (b), (c), (d), (e), (f), (g), or (h); or   (j) a multimeric construct comprising a polypeptide of (c), (d), (e), or (f); or a fragment or variant of (a), (b), (c), (d), (e), (f), (g), (h), or (i); or       

     (2) a polynucleotide encoding at least one polypeptide antigen that is selected from (1).
     Embodiment 36. The method according to embodiment 35, wherein the subject is immunocompromised.   Embodiment 37. A method for diagnosing or monitoring a  Candida  or  Aspergillus  infection in a subject, the method comprising:   

     (a) providing a gene expression profile obtained from a biological sample of the subject, wherein the expression profile comprises a plurality of  Candida  or  Aspergillus  genes that are expressed at the protein level; and 
     (b) comparing the subject&#39;s gene expression profile to a reference gene expression profile.
     Embodiment 38. The method according to embodiment 37, wherein the reference gene expression profile is obtained from a normal, healthy individual, or from an infected individual.   Embodiment 39. The method according to embodiment 37, wherein the reference gene expression profile is contained within a database.   Embodiment 40. The method according to embodiment 37, wherein said comparing is carried out using a computer algorithm.   Embodiment 41. The method according to embodiment 37, wherein said method further comprises preparing the patient&#39;s gene expression profile.   Embodiment 42. The method according to embodiment 37, wherein said method further comprises:   

     (c) providing a gene expression profile obtained from a biological sample from the subject after the subject has undergone a treatment regimen for  Candida  or  Aspergillus  infection; and 
     (d) comparing the subject&#39;s post-treatment gene expression profile to the reference gene expression profile, to monitor the subject&#39;s response to the treatment regimen.
     Embodiment 43. The method according to embodiment 37, wherein said method further comprises:   

     (c) providing a diagnosis of  Candida  or  Aspergillus  infection to the patient.
     Embodiment 44. The method according to embodiment 33, wherein the plurality of  Candida  or  Aspergillus  genes is listed in Tables 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, or 17 disclosed herein.   Embodiment 45. The method according to embodiment 37, wherein the plurality of  Candida  or  Aspergillus  genes comprises one or more polypeptides (e.g., one, two, three, or four or more polypeptides) selected from among SET1 (chromatin regulatory protein), ENO1 (enolase I), PGK1-2 (phosphoglycerate kinease), and MUC1-2 (cell surface glycoprotein).   Embodiment 46. The method according to embodiment 37, wherein the plurality of  Candida  or  Aspergillus  genes comprises one or more polypeptides (e.g., one, two, three, four, five, six, seven, eight, nine, ten, eleven, twelve, thirteen, fourteen, or fifteen or more polypeptides) selected from among MET6-1, METE-2, NOT5, RBT4, IPF9162, CAR1, GAP1, SET1, ENO1, FBA1, PGK1-1, PGK1-2, MUC1-1, MUC1-2, and BGL2.   Embodiment 47. The method according to embodiment 37, wherein the plurality of  Candida  or  Aspergillus  genes comprises one or more polypeptides (e.g., one, two, three, four, five, six, or seven or more polypeptides) selected from among SET1, ENO1, FBA1, PGK1-1, PGK1-2, MUC1-2, and BGL2.   Embodiment 48. The method according to embodiment 37, wherein the subject&#39;s gene expression profile further comprises one or more genes endogenous to the subject.   Embodiment 49. The method according to embodiment 37, wherein the subject is immunocompromised at the time the biological sample is obtained from the subject.   Embodiment 50. The method according to embodiment 37, further comprising administering an anti-fungal agent to the subject.   

     Materials and Methods  
     Definitions. Outcomes were classified as systemic candidiasis or controls. Systemic candidiasis was defined as recovery of  Candida  sp. from blood or a sterile site. Controls were defined as non-immunocompromised patients hospitalized at the Shands Teaching Hospital at the University of Florida (STH-UF) who did not have any clinical or microbiologic evidence of  candida  infection. Predictor variables were the titers of antibodies against specific antigens. 
     Study population. Over the period of thirty-six months, sera from 68 patients with systemic candidiasis was collected, including 66 patients with candidemia and 2 patients with deep-seated candidiasis (one with  candida  peritonitis related to chronic peritoneal dialysis, and one with biopsy-proven  candida  pneumonia). Patients were sub-classified into pre-term and newborn infants (&lt;6 months old), immunocompromised hosts and burn victims, as well as by portal of entry. Descriptive data for the patients are provided in Table 11. The median time from the onset of infection to serum collection was 2 days. Seven patients died, and four of the survivors had infections that persisted for over 2 weeks. Sera from 24 hospitalized patients who had no evidence of candidiasis were also collected as controls. 
     Collection of sera. Patients at STH-UF were identified on the day of positive blood or sterile site cultures for  Candida  sp. Controls were identified by the Infectious Diseases consultation service at STH-UF. After informed consent was obtained in accordance with procedures approved by the National Institutes of Health and the UF Institutional Review Board, sera were collected and stored at −70° C. in the repository at the UF Mycology Research Unit. For patients with candidiasis, sera were obtained from the earliest possible date on or after the date that the first positive cultures were drawn. In all cases, this was within 7 days of the first positive culture. 
     Enzyme-linked immunosorbent assay (ELISA). Antibody titers were evaluated for a set of twelve antigens that were identified using In Vivo Induced Antigen Technology (MET6, SET1, GAP1, ENO1, NOT5, BGL2, FBA1, MUC1, CAR1, RBT4, IPF9162 and PGK1) (Cheng, S et al.  Mol Microbiol.,  2003; 48:1275-88). Whole or partial DNA sequences of the genes encoding the antigens were amplified by polymerase chain reaction using the primers listed in Table 10. Two fragments of MET6, PGK1 and MUC1 were amplified, resulting in a total of 15 DNA sequences. The resulting PCR products were cloned into the plasmid pET30 using an EK/LIC cloning kit (EMD Biosciences, Inc.). All inserts were confirmed by DNA sequencing. Each plasmid was transformed into  E. coli  BL21(DE3) (Novagen). Expression of the recombinant proteins was induced by isopropyl-β-d-thiogalactopyranoside (IPTG). The recombinant proteins were purified from cell-free supernatants by chromatography on Ni 2+ -NTA-agarose as previously described (Cheng, S et al.  Infect Immun.,  2005; 73:7190-7). 
     96-well flat-bottom microtiter plates were coated with purified recombinant proteins in carbonate buffer (pH 9.6) at a concentration of 0.5 ug per well for 1 h at 37° C. (Cheng, S et al.  Infect Immun.,  2005; 73:7190-7). The plates were washed in PBS with 0.1% Tween-20 (PBS-T), and blocked with 0.25% gelatin in PBS-T for 1 h at 37° C. The wells were again washed with PBS-T. Serially diluted serum specimens were added to each well, and the plate incubated for 1 h at 37° C. The plates were washed, and peroxidase-conjugated goat anti-human immunoglobulin IgM (1:5,000 dilution) or IgG (1:25,000 dilution) in PBS-T was added. After an 1-hour incubation at 37° C., the plates was washed and developed with a o-phenylenediamine in citrate buffer and 5% hydrogen peroxidase. The developing solution was stopped with 1 M phosphoric acid. The optical densities (ODs) were determined using a spectrophotometer at 450 nm. Background was defined in wells coated with the protein to which the secondary antibody was added but the primary antibody was not. The reactive titer was defined as the inverse of the greatest dilution at which the OD was two-fold greater than background. All serum samples were tested in duplicate. In addition to wells lacking the primary antibody, wells that were not coated with protein were further included as negative controls. 
     Statistical analyses. Statistical significance was set at 0.05. The antibody titers for individual proteins were first log e -transformed to approximate normal distribution prior to data analysis. Multicollinearity among the predictor variables was assessed using collinearity diagnostics in SAS PROC REG. Means and standard errors for each predictor were calculated for each outcome variable. 
     Potentially significant predictor variables for the discriminant model were identified by backward elimination analysis using the STEPDISC procedure and by canonical correlation analysis using the CANCORR procedure in SAS/STAT. In the backward elimination analysis, the predictor variables chosen to leave the model were based on the significance level of an F test from an analysis of covariance. In the canonical analysis, standardized canonical coefficients, which reflect the relative contribution of each predictor variable to the power of discriminating between the two outcomes, were generated; the variables with highest absolute values were included in the discriminant model. 
     The DISCRIM procedure in SAS/STAT was used to identify the smallest subset of predictor variables that best discriminate the two outcomes. The performance of this discriminant analysis was evaluated by estimating the error rate (probability of misclassification of outcome). Finally, linear regression analysis using PROC REG in SAS was performed to generate the predicted function for the best set of predictors that were identified. The prediction score takes the form of y=a+β 1 x 1 +β 2 x 2 + . . . +β n x n , where a is the constant where the regression line intercepts the y axis and β is a regression coefficient. 
     All patents, patent applications, provisional applications, and publications referred to or cited herein, supra or infra, are incorporated by reference in their entirety, including all figures and tables, to the extent they are not inconsistent with the explicit teachings of this specification. 
     Following are examples which illustrate procedures for practicing the invention. These examples should not be construed as limiting. All percentages are by weight and all solvent mixture proportions are by volume unless otherwise noted. 
     Example 1 
     Antibody Responses Against  Candida  Proteins Among  Patients with Candidiasis  
     The present inventors measured antibody responses against immunogenic  Candida  proteins among human patients with candidemia, oropharyngeal candidiasis, and healthy controls. The patient population and underlying conditions are described in Tables 1 and 2, respectively. 
     Sera were collected within 2 weeks of diagnosis from patients with candidemia, OPC and healthy controls as part of the University of Florida Mycology Research Unit. Recombinant  C. albicans  proteins Bgl2p, Eno1p, Fba1p, Gap1p, Pgk2p, Mep6p, Set1p, Rbt4p, Car1p, Muc1p and IPF9162p were purified. Antibody titers were measured against recombinant proteins by ELISA. Results are shown in Tables 3-6 and FIGS.  1  and  2 A- 2 F. 
     
       
         
           
               
             
               
                 TABLE 1 
               
             
            
               
                   
               
               
                 Patient population 
               
            
           
           
               
               
            
               
                 Types of patients 
                 Number of patients 
               
               
                   
               
               
                 Patients with  C. albicans  candidemia 
                 32 patients 
               
               
                 Patients with oropharyngeal candidiasis (OPC) 
                 13 patients 
               
               
                 Hospitalized patients with no evidence of 
                 20 patients 
               
               
                 candidiasis (controls) 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 2 
               
             
            
               
                   
               
               
                 Underlying conditions 
               
            
           
           
               
               
            
               
                 Types of patients 
                 Percent of patients 
               
               
                   
               
               
                 Burn or trauma patients 
                 28% 
               
               
                 Patients receiving TPN 
                 17% 
               
               
                 Patients undergoing GI surgery 
                 17% 
               
               
                 Patients with diabetes mellitus and vascular diseases 
                 17% 
               
               
                 Neonates 
                 11% 
               
               
                 Other underlying illness 
                 17% 
               
               
                   
               
            
           
         
       
     
     There were no differences in IgM and IgA responses to proteins between the 3 groups. Total immunoglobulin and IgG responses, however, did differ between the groups.  FIGS. 2A-2F  show representative IgG responses against specific proteins. 
     
       
         
           
               
             
               
                 TABLE 3 
               
             
            
               
                   
               
               
                 Three types of IgG responses 
               
            
           
           
               
               
               
            
               
                   
                 Type of response 
                 Proteins 
               
               
                   
                   
               
               
                   
                 Specific to DC 
                 Rbt4, Met6, Set1, Gap1, Bgl2 
               
               
                   
                 Specific to DC and OPC 
                 Car1, Enol1, Fba1, IPF9162 
               
               
                   
                 Non-specific 
                 PGK1 
               
               
                   
                 Low immunogenicity 
                 Muc1 
               
               
                   
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 4 
               
             
            
               
                   
               
               
                 IgG response against Set1p 
               
            
           
           
               
               
               
            
               
                   
                 Antibody against Set1p 
                 Rate 
               
               
                   
                   
               
               
                   
                 Sensitivity 
                 81.2% 
               
               
                   
                 Specificity 
                   70% 
               
               
                   
                 PPV 
                 81.2% 
               
               
                   
                 NPV 
                   70%* 
               
               
                   
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 5 
               
             
            
               
                   
               
               
                 IgG response against Met6 
               
            
           
           
               
               
               
            
               
                   
                 Antibody against Met6 
                 Rate 
               
               
                   
                   
               
               
                   
                 Sensitivity 
                 87.5% 
               
               
                   
                 Specificity 
                   55% 
               
               
                   
                 PPV 
                 75.7% 
               
               
                   
                 NPV 
                  73.3%* 
               
               
                   
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 6 
               
             
            
               
                   
               
               
                 IgG response against Rbt4p 
               
            
           
           
               
               
               
            
               
                   
                 Antibody against Rbt4p 
                 Rate 
               
               
                   
                   
               
               
                   
                 Sensitivity 
                 87.5% 
               
               
                   
                 Specificity 
                 40.7% 
               
               
                   
                 PPV 
                   63% 
               
               
                   
                 NPV 
                  50.1%* 
               
               
                   
                   
               
               
                   
                 *All 4 neonates had undetected antibody 
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 7 
               
             
            
               
                   
               
               
                   C. albicans  genes and proteins identified by IVIAT screening 
               
            
           
           
               
               
               
               
               
            
               
                   
                   
                   
                 Function 
                   
               
               
                   
                   
                   
                 deduced 
               
               
                   
                   
                 Known 
                 from 
               
               
                 CandidaDB 
                 Accession 
                 function 
                 homologous 
               
               
                 designation 
                 No. 
                 in  C. albicans   
                 protein in  S. cerevisiae   
                 Description 
               
               
                   
               
               
                 Transcription 
                   
                   
                   
                   
               
               
                 Factor/Regulation 
               
               
                 Dimorphism: 
               
               
                 RBF1 
                 XM_714028; 
                 Yes 
                   
                 DNA-binding protein; 
               
               
                   
                 XM_435193 
                   
                   
                 transcription factor 
               
               
                   
                   
                   
                   
                 involves in yeast- 
               
               
                   
                   
                   
                   
                 hyphae transition 
               
               
                 CPP1 
                   
                 Yes 
                   
                 Mitogen-activated 
               
               
                   
                   
                   
                   
                 protein kinase 
               
               
                   
                   
                   
                   
                 phosphatase; suppresses 
               
               
                   
                   
                   
                   
                 hyphal growth 
               
               
                 CST20 
                 U73457 
                 Yes 
                   
                 Regulator leads to the 
               
               
                   
                   
                   
                   
                 coordinate control of 
               
               
                   
                   
                   
                   
                 hyphal development 
               
               
                 CHK1 
                   
                 Yes 
                   
                 Histidine kinase signal 
               
               
                   
                   
                   
                   
                 transduction; essential 
               
               
                   
                   
                   
                   
                 for hyphal 
               
               
                   
                   
                   
                   
                 development; regulates 
               
               
                   
                   
                   
                   
                 cell wall mannan and 
               
               
                   
                   
                   
                   
                 glucan synthesis 
               
               
                 CAP1 
                 U95611 
                 Yes 
                   
                 Adenylate cyclase- 
               
               
                   
                   
                   
                   
                 associated protein 
               
               
                   
                   
                   
                   
                 regulates adenylate 
               
               
                   
                   
                   
                   
                 cyclase activity 
               
               
                 CDC24 
                 AY208122 
                 Yes 
                   
                 GTP/GDP exchange 
               
               
                   
                   
                   
                   
                 factor for CDC42; 
               
               
                   
                   
                   
                   
                 contains RhoGEF 
               
               
                   
                   
                   
                   
                 domain (2E-43) 
               
               
                   
                   
                   
                   
                 involved in regulation 
               
               
                   
                   
                   
                   
                 of various cellular 
               
               
                   
                   
                   
                   
                 processes 
               
               
                 NOT5 
                 XM_712551; 
                 No 
                 NOT5 
                 *Subunit of the CCR4- 
               
               
                   
                 XM_436807 
                   
                 (1E-17) 
                 NOT complex, a global 
               
               
                   
                   
                   
                   
                 transcriptional regulator 
               
               
                 IPF11281 
                 AB084519 
                 No 
                 GPR1 
                 *G-protein coupled 
               
               
                   
                   
                   
                 (1E-29) 
                 receptor; regulates both 
               
               
                   
                   
                   
                   
                 pseudohyphal and 
               
               
                   
                   
                   
                   
                 invasive growth by a 
               
               
                   
                   
                   
                   
                 cAMP-dependent 
               
               
                   
                   
                   
                   
                 mechanism. 
               
               
                 Metabolism: 
               
               
                 PPR1 
                   
                 No 
                 PPR1 
                 *Transcription factor 
               
               
                   
                   
                   
                 (2E-68) 
                 regulating pyrimidine 
               
               
                   
                   
                   
                   
                 pathway (+ regulator of 
               
               
                   
                   
                   
                   
                 URA1 and URA3) 
               
               
                 IPF3598 
                   
                 No 
                 SIP3 
                 *Activator of Snflp 
               
               
                   
                   
                   
                 (2E-78) 
                 protein kinase involved 
               
               
                   
                   
                   
                   
                 in signal transduction, 
               
               
                   
                   
                   
                   
                 filamentous growth and 
               
               
                   
                   
                   
                   
                 cellular response to 
               
               
                   
                   
                   
                   
                 nitrogen starvation. 
               
               
                   
                   
                   
                   
                 Has a PH domain which 
               
               
                   
                   
                   
                   
                 is found in eukaryotic 
               
               
                   
                   
                   
                   
                 signaling pathway, a 
               
               
                   
                   
                   
                   
                 constituent of 
               
               
                   
                   
                   
                   
                 cytoskeleton 
               
               
                 IPF9385 
                   
                 No 
                 PHO2 
                 *Homeobox-domain 
               
               
                   
                   
                   
                 (2E-30) 
                 containing transcription 
               
               
                   
                   
                   
                   
                 factor; involves in 
               
               
                   
                   
                   
                   
                 regulation of phosphate 
               
               
                   
                   
                   
                   
                 metabolism 
               
               
                 Cell cycle: 
               
               
                 IPF9413 
                 XM_707295; 
                 No 
                 CLG1 
                 *Cyclin dependent 
               
               
                   
                 XM_442263 
                   
                 (4.5E-14) 
                 protein kinase 
               
               
                   
                   
                   
                   
                 holoenzyme complex, 
               
               
                   
                   
                   
                   
                 regulates acid 
               
               
                   
                   
                   
                   
                 phosphatase gene 
               
               
                   
                   
                   
                   
                 expression; involves 
               
               
                   
                   
                   
                   
                 with cell growth and 
               
               
                   
                   
                   
                   
                 division 
               
               
                 Unknown target: 
               
               
                 SPT6 
                 XM_710094 
                 No 
                 SPT6 
                 *DNA-dependent 
               
               
                   
                   
                   
                 (E-140) 
                 regulation of 
               
               
                   
                   
                   
                   
                 transcription. 
               
               
                 SET1 
                 XM_713878; 
                 Yes 
                 SET1 
                 *Chromatin-mediated 
               
               
                   
                 XM_435267 
                   
                 (2E-72) 
                 gene regulation. 
               
               
                 SAS3 
                 XM_713115; 
                   
                 SAS3 
                 *Histone 
               
               
                   
                 XM_436111 
                   
                 (1E-90) 
                 acetyltransferase, 
               
               
                   
                   
                   
                   
                 silencing protein. 
               
               
                 RPC53 
                   
                 No 
                 RPC53 
                 *DNA-directed RNA 
               
               
                   
                   
                   
                 (5E-11) 
                 polymerase III; 
               
               
                   
                   
                   
                   
                 transcription from Pol 
               
               
                   
                   
                   
                   
                 III promoter 
               
               
                 IPF2140 
                 XM_710153 
                 No 
                 CAF40 
                 *CCR-NOT complex, 
               
               
                   
                   
                   
                 (7E-92) 
                 CCR4 Associated 
               
               
                   
                   
                   
                   
                 Factor; regulates 
               
               
                   
                   
                   
                   
                 transcription from Pol II 
               
               
                   
                   
                   
                   
                 promoter. 
               
               
                 IPF19724 
                 XM_715832; 
                 No 
                 TBF1 
                 *Transcription factor 
               
               
                   
                 XM_433240 
                   
                 (2E-43) 
                 involves in loss of 
               
               
                   
                   
                   
                   
                 chromatin silencing. 
               
               
                 IPF11711 
                 XM_710225; 
                 No 
                 TOM1 
                 *E3 ubiquitin protein 
               
               
                   
                 XM_439087 
                   
                 (4.5e-250) 
                 ligase required for 
               
               
                   
                   
                   
                   
                 G2/M transition. 
               
               
                   
                   
                   
                   
                 Contains a yeast hect- 
               
               
                   
                   
                   
                   
                 domain protein which 
               
               
                   
                   
                   
                   
                 mediates transcriptional 
               
               
                   
                   
                   
                   
                 regulation 
               
               
                 IPF1009 
                   
                 No 
                 RFX1 
                 *Transcription factor 
               
               
                   
                   
                   
                 (1.4e-7) 
                 regulating a wide 
               
               
                   
                   
                   
                   
                 variety of processes; 
               
               
                   
                   
                   
                   
                 involves in DNA 
               
               
                   
                   
                   
                   
                 damage response, signal 
               
               
                   
                   
                   
                   
                 transduction resulting in 
               
               
                   
                   
                   
                   
                 cell cycle arrest 
               
               
                 IPF2971 
                   
                 No 
                   
                 Unknown function. 
               
               
                   
                   
                   
                   
                 Contains a cyclin 
               
               
                   
                   
                   
                   
                 domain that regulates 
               
               
                   
                   
                   
                   
                 cyclin-dependent 
               
               
                   
                   
                   
                   
                 kinases 
               
               
                 IPF1798 
                   
                 No 
                 No 
                 Unknown function. 
               
               
                   
                   
                   
                   
                 Contains Fungal 
               
               
                   
                   
                   
                   
                 specific transcription 
               
               
                   
                   
                   
                   
                 factor domain found in 
               
               
                   
                   
                   
                   
                 transcription activator 
               
               
                   
                   
                   
                   
                 xInR, yeast regulatory 
               
               
                   
                   
                   
                   
                 protein GAL4, and 
               
               
                   
                   
                   
                   
                 other transcription 
               
               
                   
                   
                   
                   
                 proteins regulating 
               
               
                   
                   
                   
                   
                 cellular and metabolic 
               
               
                   
                   
                   
                   
                 processes 
               
               
                 IPF4805 
                   
                 No 
                   
                 Unknown function. 
               
               
                   
                   
                   
                   
                 Contains a zinc-finger 
               
               
                   
                   
                   
                   
                 transcriptional factor 
               
               
                   
                   
                   
                   
                 with low homology to 
               
               
                   
                   
                   
                   
                 scNFL11, and a SAP 
               
               
                   
                   
                   
                   
                 domain found in diverse 
               
               
                   
                   
                   
                   
                 nuclear proteins 
               
               
                   
                   
                   
                   
                 involved in 
               
               
                   
                   
                   
                   
                 chromosomal 
               
               
                   
                   
                   
                   
                 organization 
               
               
                 STRESS 
               
               
                 RESPONSE &amp; 
               
               
                 ADAPTATION 
               
               
                 Stress response: 
               
               
                 RBT 4 
                 XM_713699; 
                 Yes 
                   
                 Filament-specific gene, 
               
               
                   
                 XM_435487 
                   
                   
                 but has no role in 
               
               
                   
                   
                   
                   
                 morphology transition. 
               
               
                   
                   
                   
                   
                 Encodes PR 
               
               
                   
                   
                   
                   
                 (pathogenesis-related) 
               
               
                   
                   
                   
                   
                 protein that is 
               
               
                   
                   
                   
                   
                 synthesized during 
               
               
                   
                   
                   
                   
                 infection, stress-related 
               
               
                   
                   
                   
                   
                 responses, serum 
               
               
                   
                   
                   
                   
                 treatment of 
               
               
                   
                   
                   
                   
                 filamentous cells, and 
               
               
                   
                   
                   
                   
                 depletion of TUP1. 
               
               
                 IPF5761 
                   
                 No 
                 FMO 
                 *A flavin-containing 
               
               
                   
                   
                   
                 (4E-32) 
                 monooxygenase 
               
               
                   
                   
                   
                   
                 involved in oxidation of 
               
               
                   
                   
                   
                   
                 biologic thiols; is vital 
               
               
                   
                   
                   
                   
                 for yeast response to 
               
               
                   
                   
                   
                   
                 reductive stress. 
               
               
                 IPF1428 
                 XM_713923; 
                 No 
                 BUL2 
                 *Contains the N- 
               
               
                   
                 XM_435312 
                   
                 (8E-18) 
                 terminus of scBUL1. 
               
               
                   
                   
                   
                   
                 Essential for growth in 
               
               
                   
                   
                   
                   
                 various stress 
               
               
                   
                   
                   
                   
                 conditions. 
               
               
                 Nutrient 
               
               
                 sensor/transport: 
               
               
                 MEP2 
                   
                 No 
                 MEP2 
                 *An ammonium 
               
               
                   
                   
                   
                 (1E-121) 
                 transport affecting 
               
               
                   
                   
                   
                   
                 pseudohyphal growth. 
               
               
                 IPF11281 
                 XM_715449; 
                 Yes 
                   
                 Proline transport helper 
               
               
                 (PTH1) 
                 XM_433638 
                   
                   
                 [Ref]. Also similar to 
               
               
                   
                   
                   
                   
                 scGpr1p, a G-protein- 
               
               
                   
                   
                   
                   
                 coupled receptor at 
               
               
                   
                   
                   
                   
                 plasma membrane; 
               
               
                   
                   
                   
                   
                 interacts in two-hybrid 
               
               
                   
                   
                   
                   
                 system with Gpa2p 
               
               
                   
                   
                   
                   
                 involving in cell growth 
               
               
                   
                   
                   
                   
                 and maintenance, 
               
               
                   
                   
                   
                   
                 pseudohyphal growth, 
               
               
                   
                   
                   
                   
                 signal transduction and 
               
               
                   
                   
                   
                   
                 sporulation. 
               
               
                 ENA22 
                   
                 No 
                 ENA5 
                 *Sodium ion transport 
               
               
                   
                   
                   
                 (0.0) 
                 (P-type ATPases) 
               
               
                   
                   
                   
                   
                 member of a 
               
               
                   
                   
                   
                   
                 superfamily cation 
               
               
                   
                   
                   
                   
                 transport enzyme, 
               
               
                   
                   
                   
                   
                 mediates membrane 
               
               
                   
                   
                   
                   
                 flux of all cations. 
               
               
                 MDL1 
                 XM_713187; 
                   
                 MDL1 
                 *ABC transporter 
               
               
                   
                 XM_436186 
                   
                 (3E-145) 
                 involves in the export 
               
               
                   
                   
                   
                   
                 of peptides from the 
               
               
                   
                   
                   
                   
                 mitochondrial matrix; 
               
               
                   
                   
                   
                   
                 regulates cellular 
               
               
                   
                   
                   
                   
                 resistance to oxidative 
               
               
                   
                   
                   
                   
                 stress. 
               
               
                 ALP1 
                 XM_708849; 
                   
                 ALP1 
                 *Basic amino acid 
               
               
                   
                 XM_440625 
                   
                 (2E-70) 
                 transporter, involved in 
               
               
                   
                   
                   
                   
                 uptake of cationic 
               
               
                   
                   
                   
                   
                 amino acids 
               
               
                 DNA repair: 
               
               
                 RAD23 
                   
                 No 
                 RAD23 
                 *Nucleotide excision 
               
               
                   
                   
                   
                 (2E-24) 
                 repair protein 
               
               
                   
                   
                   
                   
                 (ubiquitin-like protein). 
               
               
                   
                   
                   
                   
                 Also plays a role in 
               
               
                   
                   
                   
                   
                 negative regulation of 
               
               
                   
                   
                   
                   
                 protein catabolism; 
               
               
                   
                   
                   
                   
                 nucleotide-excision 
               
               
                   
                   
                   
                   
                 repair; DNA damage 
               
               
                   
                   
                   
                   
                 recognition. 
               
               
                 RFA1 
                 XM_714446; 
                 No 
                 RFA1 
                 *DNA replication 
               
               
                   
                 XM_434861 
                   
                 (1E-102) 
                 factor A, required for 
               
               
                   
                   
                   
                   
                 DNA-damage repair. 
               
               
                 IPF9141 
                   
                 No 
                 CTF4 
                 *Chromatin-associated 
               
               
                   
                   
                   
                 1E-60 
                 protein involves in 
               
               
                   
                   
                   
                   
                 DNA repair, DNA 
               
               
                   
                   
                   
                   
                 dependent DNA 
               
               
                   
                   
                   
                   
                 replication, sister 
               
               
                   
                   
                   
                   
                 chromatid cohesion, 
               
               
                   
                   
                   
                   
                 replicative cell aging. 
               
               
                 IPF19872 
                 XM_712512; 
                 No 
                   
                 Unknown function. 
               
               
                   
                 XM_436767 
                   
                   
                 Has DNA-binding 
               
               
                   
                   
                   
                   
                 protein C1D domain 
               
               
                   
                   
                   
                   
                 (3E-05) involved in 
               
               
                   
                   
                   
                   
                 regulation of double- 
               
               
                   
                   
                   
                   
                 strand break repair 
               
               
                 METABOLISM 
               
               
                 LPD1 
                 XM_707241; 
                 No 
                 LPD1 
                 *Dihydrolipoamide 
               
               
                   
                 XM_442283 
                   
                 (1E-111) 
                 dehydrogenase: 
               
               
                   
                   
                   
                   
                 involved in acetyl-CoA 
               
               
                   
                   
                   
                   
                 biosynthesis from 
               
               
                   
                   
                   
                   
                 pyruvate and amino 
               
               
                   
                   
                   
                   
                 acid catabolism. 
               
               
                 PDB1 
                   
                 No 
                 PDB1 
                 pyruvate dehydrogenase 
               
               
                   
                   
                   
                 (7E-92) 
                 involved in pyruvate 
               
               
                   
                   
                   
                   
                 metabolism 
               
               
                 MDH12 
                   
                 No 
                 MDH12 
                 *Mitochondrial malate 
               
               
                   
                   
                   
                 (2E-51) 
                 dehydrogenase involves 
               
               
                   
                   
                   
                   
                 in NADH regeneration, 
               
               
                   
                   
                   
                   
                 fatty acid oxidation, 
               
               
                   
                   
                   
                   
                 glyoxylate cycle, and 
               
               
                   
                   
                   
                   
                 malate metabolism 
               
               
                 CAR1 
                 XM_716750; 
                 No 
                 CAR1 
                 *Arginase involved in 
               
               
                   
                 XM_432299 
                   
                 (3E-59) 
                 arginine catabolism to 
               
               
                   
                   
                   
                   
                 ornithine. 
               
               
                 IPF6881 
                   
                 No 
                 
                   S. pombe 
                 
                 Function deduced by 
               
               
                   
                   
                   
                 (3E-30) 
                 homology to  S. pombe   
               
               
                   
                   
                   
                   
                 phosphatidyl synthase. 
               
               
                   
                   
                   
                   
                 Contains NagD 
               
               
                   
                   
                   
                   
                 domains with predicted 
               
               
                   
                   
                   
                   
                 sugar phosphatases of 
               
               
                   
                   
                   
                   
                 the HAD superfamily 
               
               
                   
                   
                   
                   
                 involved in 
               
               
                   
                   
                   
                   
                 carbohydrate transport 
               
               
                   
                   
                   
                   
                 and metabolism. 
               
               
                 IPF4258 
                   
                 No 
                   
                 Unknown function. 
               
               
                   
                   
                   
                   
                 Contains a eukaryotic- 
               
               
                   
                   
                   
                   
                 specific Acyl CoA 
               
               
                   
                   
                   
                   
                 binding protein domain 
               
               
                   
                   
                   
                   
                 (6E-13) involved in 
               
               
                   
                   
                   
                   
                 lipid transport and 
               
               
                   
                   
                   
                   
                 metabolism. 
               
               
                 IPF7489 
                   
                   
                 YOR171C 
                 Contains LCB5 domain 
               
               
                   
                   
                   
                 (1E-5) 
                 sphingosine kinase and 
               
               
                   
                   
                   
                   
                 diacylglycerol kinase 
               
               
                   
                   
                   
                   
                 involved in lipid 
               
               
                   
                   
                   
                   
                 metabolism. 
               
               
                 HOST- 
               
               
                 PATHOGEN 
               
               
                 INTERACTION 
               
               
                 Cell wall 
               
               
                 structure, 
               
               
                 organization and 
               
               
                 biosynthesis: 
               
               
                 MYO5 
                 XM_705894; 
                 Yes 
                 MYO5 
                 *Involved in cell wall 
               
               
                   
                 XM_443689 
                   
                 (0.0) 
                 organization and 
               
               
                   
                   
                   
                   
                 biogenesis, endocytosis, 
               
               
                   
                   
                   
                   
                 exocytosis, polar 
               
               
                   
                   
                   
                   
                 budding, response to 
               
               
                   
                   
                   
                   
                 osmotic stress, and 
               
               
                   
                   
                   
                   
                 salinity response. 
               
               
                   
                   
                   
                   
                 Required for Candida 
               
               
                   
                   
                   
                   
                 hyphal formation. 
               
               
                 PRAI 
                   
                 Yes 
                   
                 Cell wall protein with a 
               
               
                   
                   
                   
                   
                 role in pH-regulation, 
               
               
                   
                   
                   
                   
                 temperature dependent 
               
               
                   
                   
                   
                   
                 morphogenesis 
               
               
                 AMYG2 
                 XM_711719; 
                 Yes 
                 ROT2 
                 Glucoamylase. Also 
               
               
                   
                 XM_437664 
                   
                 (1E-34) 
                 similar to sc ROT2 
               
               
                   
                   
                   
                   
                 involved in cell wall 
               
               
                   
                   
                   
                   
                 biosynthesis (glucosyl 
               
               
                   
                   
                   
                   
                 hydrolase enzyme of 
               
               
                   
                   
                   
                   
                 carbohydrate 
               
               
                   
                   
                   
                   
                 metabolism) 
               
               
                 LP19 
                   
                 No 
                 MHP1 
                 *Cell wall 
               
               
                   
                   
                   
                 (2E-75) 
                 organization and 
               
               
                   
                   
                   
                   
                 biogenesis; microtubule 
               
               
                   
                   
                   
                   
                 stabilization 
               
               
                 ALG5 
                   
                   
                 ALG5 
                 *Mannosyltransferase, 
               
               
                   
                   
                   
                 (6E-95) 
                 involved in asparagine- 
               
               
                   
                   
                   
                   
                 linked glycosylation in 
               
               
                   
                   
                   
                   
                 the endoplasmic 
               
               
                   
                   
                   
                   
                 reticulum. 
               
               
                 Adherence to host 
               
               
                 cell/Flocculation 
               
               
                 HWP1 
                 AY445062 
                 Yes 
                   
                 Hyphal wall 
               
               
                   
                   
                   
                   
                 protein required for 
               
               
                   
                   
                   
                   
                 normal hyphal 
               
               
                   
                   
                   
                   
                 formation. 
               
               
                 ALS10 
                 XM_705343; 
                 Yes 
                 
                   C. albicans 
                 
                 Function deduced from 
               
               
                   
                 XM_444273 
                   
                 ALS3 
                 homology with  C. albicans   
               
               
                   
                   
                   
                   
                 ALS3, an 
               
               
                   
                   
                   
                   
                 agglutinin-like protein. 
               
               
                 IPF5185 
                   
                 No 
                 FLO1 
                 *Cell wall protein 
               
               
                   
                   
                   
                 (3E-7) 
                 involved in 
               
               
                   
                   
                   
                   
                 flocculation; binds to 
               
               
                   
                   
                   
                   
                 mannose chains on the 
               
               
                   
                   
                   
                   
                 surface of other cells. 
               
               
                 IPF10919 
                   
                 No 
                 FLO1 
                 *Cell wall protein 
               
               
                   
                   
                   
                 (1E-14) 
                 involved in 
               
               
                   
                   
                   
                   
                 flocculation; binds to 
               
               
                   
                   
                   
                   
                 mannose chains on the 
               
               
                   
                   
                   
                   
                 surface of other cells. 
               
               
                 IPF15911 
                   
                 No 
                 MUC1 
                 *Cell surface flocculin 
               
               
                   
                   
                   
                 (2E-10) 
                 with structure similar to 
               
               
                   
                   
                   
                   
                 serine/threonine-rich 
               
               
                   
                   
                   
                   
                 GPI-anchored cell wall 
               
               
                   
                   
                   
                   
                 protein. 
               
               
                 Hydrolytic 
               
               
                 enzyme: 
               
               
                 PLB4.5f 
                   
                 Yes 
                 PLB3 
                 Function deduced by 
               
               
                   
                   
                   
                 (3e-41) 
                 homology to PLB3 (3E- 
               
               
                   
                   
                   
                   
                 41): phospholipase B 
               
               
                   
                   
                   
                   
                 involved in 
               
               
                   
                   
                   
                   
                 phosphatidylserine 
               
               
                   
                   
                   
                   
                 catabolism and 
               
               
                   
                   
                   
                   
                 phosphoinositide 
               
               
                   
                   
                   
                   
                 metabolism. 
               
               
                 OTHER CELL 
               
               
                 STRUCTURES 
               
               
                 PCT1 
                   
                   
                 PCT1 
                 *Cholinephosphate 
               
               
                   
                   
                   
                 (6E-78) 
                 cytidylyltransferase 
               
               
                   
                   
                   
                   
                 involved in 
               
               
                   
                   
                   
                   
                 phosphatidylcholine 
               
               
                   
                   
                   
                   
                 biosynthesis and CDP- 
               
               
                   
                   
                   
                   
                 choline pathway. 
               
               
                 COX11 
                 XM_706452; 
                   
                 COX11 
                 *Mitochondrial protein 
               
               
                   
                 XM_443117 
                   
                 (3E-78) 
                 required for assembly 
               
               
                   
                   
                   
                   
                 of active cytochrome c 
               
               
                   
                   
                   
                   
                 oxidase, the terminal 
               
               
                   
                   
                   
                   
                 electron acceptor of the 
               
               
                   
                   
                   
                   
                 respiratory chain in 
               
               
                   
                   
                   
                   
                 mitochondria 
               
               
                 KEL1 
                   
                   
                 KEL1 
                 *Involved in cell fusion 
               
               
                   
                   
                   
                 (4E-77) 
                 and morphology; 
               
               
                   
                   
                   
                   
                 localizes to regions of 
               
               
                   
                   
                   
                   
                 polarized growth. 
               
               
                   
               
               
                 In addition, further screening has identified the following (which are included as Table 7): 
               
               
                 GAP1 (XM_715518; XM_433708), IRS4 (XM_707661; XM_441886), INP51 (XM_709454; XM_439936), SET1, SET2 (XM_709308; XM_440093), DOT1 (XM_710974; XM_438330), ENO1 (XM_706790; XM_442766), BGL2 (XM_717544; XM_431403), FBA1, MUC1, IPF9162, BUR2, PGK1 (XM_706231; XM_443352) 
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 8 
               
             
            
               
                   
               
               
                   A. fumigatus  genes and proteins identified by IVIAT screening 
               
            
           
           
               
               
               
            
               
                   
                   A. fumigatus  clone 
                 Function 
               
               
                   
                   
               
            
           
           
               
               
               
            
               
                 C17.3 
                 
                   Aspergillus fumigatus 
                 
                 Putative serine-threonine protein kinase with 
               
               
                   
                 Afu2g10620 
                 homology to  S. cerevisiae  YPK1 and YPK2, which 
               
               
                   
                   
                 are required for receptor-mediated endocytosis and 
               
               
                   
                   
                 are involved in the cell integrity signaling pathway 
               
               
                 W11 
                 
                   Garden petunia 
                 
                 Catalyzes final step in ethylene biosynthesis 
               
               
                   
                 ACC oxidase I (32%) 
               
               
                 W12 
                 
                   Aspergillus nidulans 
                 
                 Hypothetical protein containing NmrA-like domain, 
               
               
                   
                 AN8970.2 (31%) 
                 which is part of a system controlling nitrogen 
               
               
                   
                   
                 metabolite repression 
               
               
                 W10 
                 
                   Aspergillus nidulans 
                 
                 Hypothetical protein containing an E3-ubiquitin 
               
               
                   
                 AN2162.2 (56%) 
                 protein ligase domain 
               
               
                 W6 
                 
                   Aspergillus nidulans 
                 
                 Hypothetical protein containing a guanine 
               
               
                   
                 AN6709.2 (47%) 
                 nucleotide exchange factor domain. Similar 
               
               
                   
                   
                 domains are found in yeast proteins regulating 
               
               
                   
                   
                 vesicle trafficking in endocytosis and exocytosis 
               
               
                 W3 
                 
                   Aspergillus nidulans 
                 
                 Hypothetical protein containing a WD domain. 
               
               
                   
                 AN7704.2 (69%) 
                 Proteins containing WD domains regulate diverse 
               
               
                   
                   
                 processes in eukaryotes (often in a species-specific 
               
               
                   
                   
                 manner) and are especially prevalent in chromatin 
               
               
                   
                   
                 modification and transcriptional mechanisms 
               
               
                 A01 
                 
                   Saccharomyces 
                 
                 tRNA C-5 methyltransferase 
               
               
                   
                   cerevisiae  YBL024w 
               
               
                 B01 
                 
                   Aspergillus fumigatus 
                 
                 Putative DNA-directed RNA polymerase 
               
               
                   
                 CAF32099 
               
               
                 C16.3 
                 
                   Aspergillus nidulans 
                 
                 Hypothetical protein containing a putative 
               
               
                   
                 AN7465.2 
                 cohesion complex protein domain 
               
               
                 C17.9 
                 
                   Aspergillus nidulans 
                 
                 Hypothetical protein with homology to  S. cerevisiae   
               
               
                   
                 AN4541.2 
                 NNTI, which encodes nicotinamide N- 
               
               
                   
                   
                 methyltransferase (involved in rDNA silencing) 
               
               
                 C19.5 
                 
                   Aspergillus nidulans 
                 
                 Hypothetical protein, putative acetyl transferase 
               
               
                   
                 AN3628.2 
               
               
                 C20.5 
                 
                   Aspergillus nidulans 
                 
                 Hypothetical protein containing a conserved GTP 
               
               
                   
                 AN EAA58968 
                 binding protein domain 
               
               
                 D04 
                 
                   Aspergillus nidulans 
                 
                 Hypothetical protein, contains a clavamic acid 
               
               
                   
                 AN2960.2 
                 synthetase (CAS)-like domain 
               
               
                 D06 
                 
                   Aspergillus nidulans 
                 
                 Hypothetical protein, contains a formyl transferase RING 
               
               
                   
                 AN5922.2 
                 domain (Zinc binding) 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 9 
               
             
            
               
                   
               
               
                 Classifications of proteins used as targets for antibody detection 
               
            
           
           
               
               
               
               
               
            
               
                   
                 Protein 
                   
                   
                   
               
               
                 Classification 
                 name 
                 Protein description 
                 Note 
                 Reference 
               
               
                   
               
               
                 classic cell 
                 BGL2 
                 glucan 1,3-β- 
                 protein reported by our 
                 Pitarch, A et 
               
               
                 wall proteins 
                   
                 glucosidase 
                 lab as well as other 
                 al. Mol Cell 
               
               
                   
                   
                   
                 groups to elicit higher 
                 Proteomics, 
               
               
                   
                   
                   
                 antibody responses 
                 2006; 5: 79-96 
               
               
                   
                   
                   
                 among patients with 
               
               
                   
                   
                   
                 systemic candidiasis 
               
               
                   
                   
                   
                 than un-infected 
               
               
                   
                   
                   
                 controls 
               
               
                   
                 MUC1 
                 cell surface 
                 Protein not been 
                 (our lab) 
               
               
                   
                   
                 glycoprotein 
                 previously reported to 
               
               
                   
                   
                   
                 be immunogenic 
               
               
                 glycolytic 
                 ENO1 
                 enolase I 
                 protein reported by our 
                 van 
               
               
                 enzymes 
                   
                   
                 lab as well as other 
                 Deventer, AJ 
               
               
                 localized to 
                   
                   
                 groups to elicit higher 
                 et al. 
               
               
                 the cell wall 
                   
                   
                 antibody responses 
                 Microbiol 
               
               
                   
                   
                   
                 among patients with 
                 Immunol., 
               
               
                   
                   
                   
                 systemic candidiasis 
                 1996; 
               
               
                   
                   
                   
                 than un-infected 
                 40: 125-31; 
               
               
                   
                   
                   
                 controls 
                 Mitsutake, K 
               
               
                   
                   
                   
                   
                 et al. J 
               
               
                   
                   
                   
                   
                 Clin Lab 
               
               
                   
                   
                   
                   
                 Anal., 1994; 
               
               
                   
                   
                   
                   
                 8: 207-10; 
               
               
                   
                   
                   
                   
                 Mitsutake, K 
               
               
                   
                   
                   
                   
                 et al. J 
               
               
                   
                   
                   
                   
                 Clin 
               
               
                   
                   
                   
                   
                 Microbiol., 
               
               
                   
                   
                   
                   
                 1996; 1918-21 
               
               
                   
                 FBA1 
                 FBA1 
                 protein reported by our 
                 Pitarch, A et 
               
               
                   
                   
                   
                 lab as well as other 
                 al. Mol Cell 
               
               
                   
                   
                   
                 groups to elicit higher 
                 Proteomics, 
               
               
                   
                   
                   
                 antibody responses 
                 2006; 5: 79-96 
               
               
                   
                   
                   
                 among patients with 
               
               
                   
                   
                   
                 systemic candidiasis 
               
               
                   
                   
                   
                 than un-infected 
               
               
                   
                   
                   
                 controls 
               
               
                   
                 GAP1 
                 glyceraldehyde-3- 
                 protein reported by our 
                 Pitarch, A et 
               
               
                   
                   
                 phosphate 
                 lab as well as other 
                 al. Mol Cell 
               
               
                   
                   
                 dehydrogenase 
                 groups to elicit higher 
                 Proteomics, 
               
               
                   
                   
                   
                 antibody responses 
                 2006; 5: 79-96 
               
               
                   
                   
                   
                 among patients with 
               
               
                   
                   
                   
                 systemic candidiasis 
               
               
                   
                   
                   
                 than un-infected 
               
               
                   
                   
                   
                 controls 
               
               
                   
                 PGK1 
                 phosphoglycerate 
                 protein reported by our 
                 Pitarch, A et 
               
               
                   
                   
                 kinase 
                 lab as well as other 
                 al. Mol Cell 
               
               
                   
                   
                   
                 groups to elicit higher 
                 Proteomics, 
               
               
                   
                   
                   
                 antibody responses 
                 2006; 5: 79-96 
               
               
                   
                   
                   
                 among patients with 
               
               
                   
                   
                   
                 systemic candidiasis 
               
               
                   
                   
                   
                 than un-infected 
               
               
                   
                   
                   
                 controls 
               
               
                 intracellular 
                 NOT5 
                 a member of the 
                 Protein previously 
                 Cheng, S et 
               
               
                 proteins 
                   
                 transcription 
                 shown by our labs to 
                 al. Mol 
               
               
                 localized to 
                   
                 regulatory CCR4- 
                 contribute to virulence 
                 Microbiol., 
               
               
                 cell wall 
                   
                 NOT complex 
                 and to elicit higher 
                 2003; 
               
               
                   
                   
                   
                 antibody responses 
                 48: 1275-88 
               
               
                   
                   
                   
                 among patients with 
               
               
                   
                   
                   
                 systemic candidiasis 
               
               
                   
                   
                   
                 than un-infected 
               
               
                   
                   
                   
                 controls 
               
               
                   
                 MET6 
                 5- 
                 protein reported by our 
                 Pitarch, A et 
               
               
                   
                   
                 methyltetrahydropteroyltri- 
                 lab as well as other 
                 al. Mol Cell 
               
               
                   
                   
                 glutamate 
                 groups to elicit higher 
                 Proteomics, 
               
               
                   
                   
                 homocysteine 
                 antibody responses 
                 2006; 5: 79-96 
               
               
                   
                   
                 methyltransferase 
                 among patients with 
               
               
                   
                   
                   
                 systemic candidiasis 
               
               
                   
                   
                   
                 than un-infected 
               
               
                   
                   
                   
                 controls 
               
               
                 intracellular 
                 CAR1 
                 arginase 
                 Protein not been 
                 Our lab 
               
               
                 proteins, 
                   
                   
                 previously reported to 
               
               
                 likely not 
                   
                   
                 be immunogenic 
               
               
                 localized to 
               
               
                 cell wall 
               
               
                   
                 RBT4 
                 repressor of TUP1 
                 Protein not been 
                 Our lab 
               
               
                   
                   
                   
                 previously reported to 
               
               
                   
                   
                   
                 be immunogenic 
               
               
                   
                 SET1 
                 chromatin 
                 Protein previously 
                 Raman, SB 
               
               
                   
                   
                 regulatory protein 
                 shown by our labs to 
                 et al. Mol 
               
               
                   
                   
                   
                 contribute to virulence 
                 Microbiol., 
               
               
                   
                   
                   
                 and to elicit higher 
                 2006; 
               
               
                   
                   
                   
                 antibody responses 
                 60: 697-709 
               
               
                   
                   
                   
                 among patients with 
               
               
                   
                   
                   
                 systemic candidiasis 
               
               
                   
                   
                   
                 than un-infected 
               
               
                   
                   
                   
                 controls 
               
               
                   
                 IPF11897 
                 protein of 
                 Protein not been 
                 Our lab 
               
               
                   
                   
                 unknown function. 
                 previously reported to 
               
               
                   
                   
                   
                 be immunogenic 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 10 
               
             
            
               
                   
               
               
                 Primers used for cloning of antigens 
               
            
           
           
               
               
               
               
               
            
               
                   
                   
                 Anti-sense primers (3′ 
                 Length of antigen 
                   
               
               
                 Antigens 
                 Sense primers (5′→ 3′) 
                 → 5′) 
                 (amino acids) 
               
               
                   
               
               
                 MET6-1 
                 5′GACGACGACAAGAT 
                 5′GAGGAGAAGCCC 
                 400 aa 
                   
               
               
                   
                 GGTTCAATCTTCCGTC 
                 GGTTAAGAAGATTC 
                 (position 1-400 aa) 
               
               
                   
                 TTAGGT (SEQ ID NO: 1) 
                 GGATCTAGC (SEQ ID 
               
               
                   
                   
                 NO: 2) 
               
               
                   
               
               
                 MET6-2 
                 5′GACGACGACAAGAT 
                 5′GAGGAGAAGCCC 
                 367 aa 
               
               
                   
                 GATACCAACGATCCAA 
                 GGTTAGTATTTAGC 
                 (position 401-768) 
               
               
                   
                 AG (SEQ ID NO: 3) 
                 TCTGAATTC (SEQ ID 
               
               
                   
                   
                 NO: 4) 
               
               
                   
               
               
                 RBT4 
                 5′GACGACGACAAGAT 
                 5′GAGGAGAAGCCC 
                 359 aa 
               
               
                   
                 GAAGTTTTCTCAAGTT 
                 GGTAATAACACCAG 
                 (entire gene) 
               
               
                   
                 GCCACTACTGCTGCTG 
                 AGTTCTGTAAAAGT 
               
               
                   
                 CCATT (SEQ ID NO: 5) 
                 CGGTA (SEQ ID NO: 
               
               
                   
                   
                 6) 
               
               
                   
               
               
                 IPF9162 
                 5′GACGACGACAAGAT 
                 5′GAGGAGAAGCCC 
                 272 aa 
               
               
                   
                 GAAAAAAAGGTTAGT 
                 GGTAATTTATCAAT 
                 (entire gene) 
               
               
                   
                 TTTGTTTGATGATTCT 
                 TTACATATAGTGCT 
               
               
                   
                 GATGAT (SEQ ID NO: 7) 
                 CAAAATGGACCTGT 
               
               
                   
                   
                 CAA (SEQ ID NO: 8) 
               
               
                   
               
               
                 CAR1 
                 5′GACGACGACAAGAT 
                 5′GAGGAGAAGCCC 
                 318 aa 
               
               
                   
                 GTCATCAATTCAATAT 
                 GGTAATGTTATTTC 
                 (entire gene) 
               
               
                   
                 AAATATCATCCAGACA 
                 AAACTGGGTTACGT 
               
               
                   
                 A (SEQ ID NO: 9) 
                 GTAGAT (SEQ ID NO: 
               
               
                   
                   
                 10) 
               
               
                   
               
               
                 GAP1 
                 5′GACGACGACAAGAT 
                 5′GAGGAGAAGCCC 
                 336 aa 
               
               
                   
                 GGCTATTAAAATT 
                 GGTTAAGCAGAAGC 
                 (entire gene) 
               
               
                   
                 GGTATTAAC (SEQ ID 
                 TTTAGCAAC (SEQ ID 
               
               
                   
                 NO: 11) 
                 NO: 12) 
               
               
                   
               
               
                 ENO1 
                 5′GACGACGACAAGAT 
                 5′GAGGAGAAGCCC 
                 441 aa 
               
               
                   
                 GTCTTACGCCACTAAA 
                 GGTTACAATTGAGA 
                 (entire gene) 
               
               
                   
                 ATCCAC (SEQ ID NO: 
                 AGCCTTTTGGAA 
               
               
                   
                 13) 
                 (SEQ ID NO: 14) 
               
               
                   
               
               
                 BGL2 
                 5′GACGACGACAAGAT 
                 5′GAGGAGAAGCCC 
                 309 aa 
               
               
                   
                 GCAAATCAAATTCTTG 
                 GGTTAGTTGAATTT 
                 (entire gene) 
               
               
                   
                 ACTACT (SEQ ID NO: 
                 ACAGTCAATTGA 
               
               
                   
                 15) 
                 (SEQ ID NO: 16) 
               
               
                   
               
               
                 FBA1 
                 5′GACGACGACAAGAT 
                 5′GAGGAGAAGCCC 
                 360 aa 
               
               
                   
                 GGCTCCTCCAGCAGTT 
                 GGTTACAATTGTCC 
                 (entire gene) 
               
               
                   
                 TTAAGT (SEQ ID NO: 
                 TTTGGTGTGGAA 
               
               
                   
                 17) 
                 (SEQ ID NO: 18 
               
               
                   
               
               
                 MUC1-1 
                 5′GACGACGACAAGAT 
                 5′GAGGAGAAGCCC 
                 306 aa 
               
               
                   
                 GTCATTTTGGGACAAC 
                 GGTTAGGTTGAGTT 
                 (position 1-306) 
               
               
                   
                 AACAA (SEQ ID NO: 19) 
                 ATTGGTTAAAA (SEQ 
               
               
                   
                   
                 ID NO: 20) 
               
               
                   
               
               
                 MUC1-2 
                 5′GACGACGACAAGAT 
                 5′GAGGAGAAGCCC 
                 153 aa 
               
               
                   
                 GGAGTATATCGCATCT 
                 GGTTATTCATGTGG 
                 (position 735-888) 
               
               
                   
                 TGGTGT (SEQ ID NO: 
                 CATTGCTCGATA 
               
               
                   
                 21) 
                 (SEQ ID NO: 22) 
               
               
                   
               
               
                 PGK1-1 
                 CA-EXP-FOR 
                 CAPKG1-F1-REV 
                 238 aa 
               
               
                   
                 5′GACGACGACAAGAT 
                 5′GAGGAGAAGCCC 
                 (position 1-238) 
               
               
                   
                 GTCATTATCTAACAAA 
                 GGTTAACCACCACC 
               
               
                   
                 TTATCA (SEQ ID NO: 
                 AACAATC (SEQ ID 
               
               
                   
                 23) 
                 NO: 24) 
               
               
                   
               
               
                 PGK1-2 
                 5′GACGACGACAAGAT 
                 5′GAGGAGAAGCCC 
                 180 aa 
               
               
                   
                 GGCCTTCACTTTCAAG 
                 GGTTAGTTTTTGTTG 
                 (position 239-438) 
               
               
                   
                 AAA (SEQ ID NO: 25) 
                 GAAAGAGC (SEQ ID 
               
               
                   
                   
                 NO: 26) 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 11 
               
             
            
               
                   
               
               
                 Descriptive data of patients with systemic candidiasis 
               
            
           
           
               
               
               
            
               
                   
                 Characteristics 
                 Number of patients 
               
               
                   
                   
               
               
                   
                 Age: 
                   
               
               
                   
                 Median (range) 
                 51.5 years (3 days to 81 years) 
               
               
                   
                 Age &lt; 6 month old 
                  8 patients 
               
               
                   
                 Immunocompromised 
                 12 patients 1   
               
               
                   
                 Burn victims 
                  8 patients 
               
               
                   
                 Portal of entry: 
               
               
                   
                 Catheter 
                 33 patients 
               
               
                   
                 Abdominal 
                 21 patients 
               
               
                   
                 Wound 
                  6 patients 
               
               
                   
                 Complications: 
               
               
                   
                 Endocarditis 
                  2 patients 
               
               
                   
                 Mediastinitis 
                  2 patients 
               
               
                   
                 Vascular graft infection 
                  2 patients 
               
               
                   
                   Candida  spp.: 
               
               
                   
                 
                   Candida albicans 
                 
                 28 patients 2   
               
               
                   
                 Non- C. albicans   
               
               
                   
                 
                   C. glabrata 
                 
                 19 patients 
               
               
                   
                 
                   C. parapsilosis 
                 
                 10 patients 3   
               
               
                   
                 
                   C. tropicalis 
                 
                  5 patients 
               
               
                   
                 
                   C. krusei 
                 
                  4 patients 
               
               
                   
                 
                   C. lusitaniae 
                 
                  1 patient 
               
               
                   
                 unspeciated 
                  1 patient 
               
               
                   
                   
               
               
                   
                   1 three bone marrow transplant recipients, 5 solid transplant recipients, and 1 both BMT and SOT recipient, 2 patients with hematologic malignancy on chemotherapy, and one patient with systemic lupus on high dose steroid. 
               
               
                   
                   2 three patients were co-infected with  C. glabrata ,  C. parapsilosis ,  C. tropicalis . 
               
               
                   
                   3 a patient was co-infected with  C. guilliermondii   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 12 
               
             
            
               
                   
               
               
                 Performance tests of antibody against specific proteins 
               
            
           
           
               
               
               
               
               
            
               
                   
                   
                   
                 Likelihood 
                   
               
               
                   
                 Sensitivity 
                 Specificity 
                 ratio 
                 p-value 
               
               
                   
                   
               
            
           
           
               
               
               
               
               
            
               
                 MET6-1 
                   65% (39/60) 
                 83.3% (20/24) 
                 3.9 
                 &lt;0.0001 
               
               
                 MET6-2 
                   60% (36/60) 
                 54.2% (13/24) 
                 1.3 
                 NS 
               
               
                 NOT5 
                   85% (51/60) 
                 87.5% (21/24) 
                 6.8 
                 &lt;0.0001 
               
               
                 SET1 
                 98.3% (59/60) 
                 66.7% (16/24) 
                 3.0 
                 &lt;0.0001 
               
               
                 RBT4 
                 98.3% (59/60) 
                 62.5% (15/24) 
                 2.6 
                 &lt;0.0001 
               
               
                 IPF9162 
                 96.7% (58/60) 
                   50% (12/24) 
                 1.9 
                 &lt;0.0001 
               
               
                 CAR1 
                   90% (54/60) 
                   75% (18/24) 
                 3.6 
                 &lt;0.0001 
               
               
                 GAP1 
                 91.7% (55/60) 
                 87.5% (21/24) 
                 7.3 
                 &lt;0.0001 
               
               
                 ENO1 
                 98.3% (59/60) 
                 70.8% (17/24) 
                 3.4 
                 &lt;0.0001 
               
               
                 BGL2 
                   95% (57/60) 
                   75% (18/24) 
                 3.8 
                 &lt;0.0001 
               
               
                 FBA1 
                 93.3% (56/60) 
                 91.7% (22/24) 
                 11.2 
                 &lt;0.0001 
               
               
                 MUC1-1 
                 96.7% (58/60) 
                   50% (12/24) 
                 1.9 
                 &lt;0.0001 
               
               
                 MUC1-2 
                 86.7% (52/60) 
                 54.2% (13/24) 
                 1.9 
                 0.0002 
               
               
                 PGK1-1 
                  72.9% (43/59)* 
                  56.5% (13/23)* 
                 1.7 
                 0.02 
               
               
                 PGK1-2 
                  62.7% (37/59)* 
                  52.2% (12/23)* 
                 1.3 
                 NS 
               
               
                   
               
               
                 *one patient from the systemic candidiasis group and one from the control group did not have sufficient sera to perform antibody response to PGK1-1 and PGK1-2. 
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 13 
               
             
            
               
                   
               
               
                 Rank order of predictors identified using canonical correlation analysis 
               
            
           
           
               
               
            
               
                 Antibodies to specific antigens 
                 Standardized canonical coefficients 
               
               
                   
               
            
           
           
               
               
            
               
                 SET1 
                 0.574 
               
               
                 MUC1-2 
                 −0.324 
               
               
                 FBA1 
                 0.318 
               
               
                 PGK-1 
                 0.309 
               
               
                 PGK-2 
                 −0.302 
               
               
                 BGL2 
                 −0.298 
               
               
                 ENO1 
                 0.272 
               
               
                 IPF9162 
                 0.196 
               
               
                 NOT5 
                 0.100 
               
               
                 RBT4 
                 0.080 
               
               
                 MET6-1 
                 0.058 
               
               
                 GAP1 
                 −0.021 
               
               
                 CAR1 
                 0.017 
               
               
                 MUC1-1 
                 −0.018 
               
               
                 MET6-2 
                 −0.001 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 14 
               
             
            
               
                   
               
               
                 Performance of the full model as well as with subsets of predictors 
               
               
                 chosen by backward elimination and canonical analyses 
               
            
           
           
               
               
               
               
            
               
                 Model 
                 Error 
                 Sensitivity 
                 Specificity 
               
               
                   
               
               
                 Full model (with 15 
                 3.7% (3/82)* 
                 96.6% (57/59)* 
                 95.6% (22/23)* 
               
               
                 predictors) 
               
               
                 SET1, ENO1, FBA1, 
                 3.7% (3/82)* 
                 96.6% (57/59)* 
                 95.6% (22/23)* 
               
               
                 PGK1-1, PGK1-2, 
               
               
                 MUC1-2, BGL2 
               
               
                 SET1, ENO1, PGK1-2, 
                 3.7% (3/82)* 
                 96.6% (57/59)* 
                 95.6% (22/23)* 
               
               
                 MUC1-2 
               
               
                 SET1, ENO1, MUC1-2 
                 4.8% (4/84)  
                 95.0% (57/60)  
                 95.8% (23/24)  
               
               
                   
               
               
                 *2 patients (one from the systemic candidiasis group and one from the control group) had limited serum; antibody titers were sufficient to test only against 14 predictor variables (all predictors except PGK1). 
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 15 
               
             
            
               
                   
               
               
                 Serum IgG responses against specific antigens 
               
            
           
           
               
               
               
               
            
               
                   
                   
                 Standard error Mean 
                   
               
               
                   
                 Mean of log 2 titer ± 
                 of log 2 titer ± 
               
               
                   
                 standard error of 
                 standard error of 
               
               
                 Predictor variable 
                 patients with DC 
                 control patients 
                 P-value 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 BGL2 
                 8.69 ± 0.27 
                 4.32 ± 0.36 
                 &lt;0.0001 
               
               
                 PGK1-1 
                 7.93 ± 0.27 
                 2.20 ± 0.46 
                 0.01 
               
               
                 PKG1-2 
                 7.49 ± 0.26 
                 6.52 ± 0.43 
                 0.05 
               
               
                 CAR1 
                 8.40 ± 0.28 
                 4.28 ± 0.35 
                 &lt;0.0001 
               
               
                 ENO1 
                 9.07 ± 0.26 
                 4.46 ± 0.38 
                 &lt;0.0001 
               
               
                 FBA1 
                 8.49 ± 0.29 
                 3.60 ± 0.19 
                 &lt;0.0001 
               
               
                 7GAP1 
                 8.38 ± 0.29 
                 3.74 ± 0.23 
                 &lt;0.0001 
               
               
                 IPF9162 
                 8.92 ± 0.22 
                 5.14 ± 0.39 
                 &lt;0.0001 
               
               
                 MET6-1 
                 8.67 ± 0.28 
                 6.28 ± 0.50 
                 0.0002 
               
               
                 MET6-2 
                 9.60 ± 0.21 
                 8.57 ± 0.48 
                 0.02 
               
               
                 MUC1-1 
                 8.72 ± 0.23 
                 5.86 ± 0.56 
                 &lt;0.0001 
               
               
                 MUC1-2 
                 8.69 ± 0.24 
                 7.02 ± 0.52 
                 0.001 
               
               
                 NOT5 
                 8.18 ± 0.37 
                 3.74 ± 0.23 
                 &lt;0.0001 
               
               
                 RBT4 
                 9.42 ± 0.27 
                 4.78 ± 0.40 
                 &lt;0.0001 
               
               
                 SET1 
                 9.16 ± 0.22 
                 4.51 ± 0.36 
                 &lt;0.0001 
               
               
                   
               
            
           
         
       
     
     
       
         
           
               
             
               
                 TABLE 16 
               
             
            
               
                   
               
               
                 Backward selection procedure to identify variables best 
               
               
                 distinguishing class membership. The table lists the order 
               
               
                 by which the variables were removed. 
               
            
           
           
               
               
               
               
               
               
               
            
               
                   
                   
                   
                   
                   
                   
                 Average 
               
               
                   
                 Number 
                   
                   
                   
                   
                 squared 
               
               
                   
                 of 
                 Variables 
                 Partial 
                   
                   
                 canonical 
               
               
                 Step 
                 variables 
                 removed 
                 R 2   
                 F value 
                 P-value 
                 correlation 
               
               
                   
               
            
           
           
               
               
               
               
               
               
               
            
               
                 0 
                 15 
                   
                   
                   
                   
                 0.7345 
               
               
                 1 
                 14 
                 MET6-F2 
                 0.0000 
                 0.00 
                 0.99 
                 0.7345 
               
               
                 2 
                 13 
                 CAR1 
                 0.0001 
                 0.01 
                 0.93 
                 0.7344 
               
               
                 3 
                 12 
                 GAP1 
                 0.0001 
                 0.01 
                 0.93 
                 0.7344 
               
               
                 4 
                 11 
                 MUC1-F1 
                 0.0002 
                 0.01 
                 0.92 
                 0.7344 
               
               
                 5 
                 10 
                 MET6-F1 
                 0.0016 
                 0.11 
                 0.74 
                 0.7340 
               
               
                 6 
                 9 
                 RBT4 
                 0.0024 
                 0.17 
                 0.68 
                 0.7333 
               
               
                 7 
                 8 
                 NOT5 
                 0.0169 
                 1.24 
                 0.27 
                 0.7288 
               
               
                 8 
                 7 
                 BGL2 
                 0.0206 
                 1.53 
                 0.22 
                 0.7230 
               
               
                 9 
                 6 
                 FBA1 
                 0.0160 
                 1.20 
                 0.28 
                 0.7185 
               
               
                 10 
                 5 
                 IPF 
                 0.0412 
                 3.23 
                 0.08 
                 0.7064 
               
               
                 11 
                 4 
                 PKG1-F1 
                 0.0497 
                 3.98 
                 0.05 
                 0.6911 
               
               
                 12 
                 3 
                 PKG1-F2 
                 0.0218 
                 1.72 
                 0.19 
                 0.6819 
               
               
                 13 
                 2 
                 MUC1-F2 
                 0.0869 
                 7.42 
                 0.008 
                 0.6541 
               
               
                 14 
                 1 
                 ENOL 
                 0.1428 
                 13.16 
                 0.0005 
                 0.560 
               
               
                 15 
                 0 
                 SET 
                 0.5965 
                 118.28 
                 &lt;0.0001 
               
               
                   
               
            
           
         
       
     
     The F-values denote the distances between the two outcomes in the multivariate model. 
     The F-test of significance (p-value) denotes significance level of the discriminant function as a whole at each elimination step. (the difference of specific predictor between the two outcome means at each elimination step). 
     
       
         
           
               
             
               
                 TABLE 17 
               
             
            
               
                   
               
               
                 Weights contributed by the specific antibodies in predicting class 
               
               
                 memberships 
               
            
           
           
               
               
               
            
               
                   
                 Predictors 
                 Standardized canonical coefficient 
               
               
                   
                   
               
            
           
           
               
               
               
            
               
                   
                 SET1 
                 1.29 
               
               
                   
                 ENOL 
                 0.911 
               
               
                   
                 MUC1-F2 
                 −0.39 
               
               
                   
                 PKG1-F2 
                 −0.20 
               
               
                   
                   
               
            
           
         
       
     
     
       
         
           
               
               
             
               
                 TABLE 18 
               
               
                   
               
             
            
               
                 1. RBF1 
                   
               
               
                 MSSNKNQSDLNIPTNSASLKQKQRQQLGIKSEIGASTSDVYDPQVASYLSAGDSPSQFANTALHHSNSVSYS 
               
               
                   
               
               
                 ASAAAAAAELQHRAELQRRQQQLQQQELQHQQEQLQQYRQAQAQAQAQAQAQAQAQREHQQLQHAYQQQQQL 
               
               
                   
               
               
                 HQLGQLSQQLAQPHLSQHEHVRDALTTDEFDTNEDLRSRYIENEIVKTFNSKAELVHFVKNELGPEERCKIV 
               
               
                   
               
               
                 INSSKPKAVYFQCERSGSFRTTVKDATKRQRIAYTKRNKCAYRLVANLYPNEKDQKRKNKPDEPGHNEENSR 
               
               
                   
               
               
                 ISEMWVLRMINPQHNHAPDPINKKKRQKTSRTLVEKPINKPHHHHLLQQEQQQQQQQQQQQQQQQQQQQQQQ 
               
               
                   
               
               
                 HNANSQAQQQAAQLQQQMQQQLQASGLPTTPNYSELLGQLGQLSQQQSQQQQLHHIPQQRQRTQSQQSQQQP 
               
               
                   
               
               
                 QQTPHGLDQPDAAVIAAIEASAAAAVASQGSPNVTAAAVAALQHTQGNEHDAQQQQDRGGNNGGAIDSNVDP 
               
               
                   
               
               
                 SLDPNVDPNVQAHDHSHGLRNSYGKRSGFL* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 HEHVRDALTTDEFDTN 
                 162 
                 0.93 
               
               
                 2 
                 GGAIDSNVDPSLDPNV 
                 495 
                 0.92 
               
               
                 3 
                 DRGGNNGGAIDSNVDP 
                 489 
                 0.90 
               
               
                 4 
                 SGLPTTPNYSELLGQL 
                 385 
                 0.88 
               
               
                 4 
                 AYTKRNKCAYRLVANL 
                 249 
                 0.88 
               
               
                 5 
                 LVANLYPNEKDQKRKN 
                 260 
                 0.87 
               
               
                 6 
                 ASYLSAGDSPSQFANT 
                 46 
                 0.86 
               
               
                 7 
                 EIGASTSDVYDPQVAS 
                 32 
                 0.84 
               
               
                 7 
                 HNHAPDPINKKKRQKT 
                 302 
                 0.84 
               
               
                 8 
                 QKRKNKPDEPGHNEEN 
                 271 
                 0.83 
               
               
                 9 
                 QQMQQQLQASGLPTTP 
                 376 
                 0.82 
               
               
                 10 
                 EKPINKPHHHHLLQQE 
                 323 
                 0.81 
               
               
                 10 
                 TKRQRIAYTKRNKCAY 
                 243 
                 0.81 
               
               
                 11 
                 DSPSQFANTALHHSNS 
                 53 
                 0.80 
               
               
                 11 
                 DPNVQAHDHSHGLRNS 
                 511 
                 0.80 
               
               
                 11 
                 RQKTSRTLVEKPINKP 
                 314 
                 0.80 
               
               
                 12 
                 QQQQQQQQQHNANSQA 
                 352 
                 0.79 
               
               
                 12 
                 CERSGSFRTTVKDATK 
                 229 
                 0.79 
               
               
                 12 
                 VHFVKNELGPEERCKI 
                 200 
                 0.79 
               
               
                 13 
                 AAAAAAELQHRAELQR 
                 75 
                 0.77 
               
               
                 13 
                 ALQHTQGNEHDAQQQQ 
                 473 
                 0.77 
               
               
                 14 
                 QRTQSQQSQQQPQQTP 
                 421 
                 0.76 
               
               
                 14 
                 WVLRMINPQHNHAPDP 
                 293 
                 0.76 
               
               
                 14 
                 CKIVINSSKPKAVYFQ 
                 213 
                 0.76 
               
               
                 14 
                 YRQAQAQAQAQAQAQA 
                 110 
                 0.76 
               
               
                 15 
                 KQRQQLGIKSEIGAST 
                 22 
                 0.75 
               
               
                 15 
                 EFDTNEDLRSRYIENE 
                 173 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 255 
                 264 
                 259 
                 KCAYRLVANL 
               
               
                 197 
                 206 
                 200 
                 AELVHFVKNE 
               
               
                 222 
                 232 
                 226 
                 PKAVYFQCERS 
               
               
                 327 
                 338 
                 332 
                 NKPHHNHLLQQE 
               
               
                 463 
                 476 
                 471 
                 SPNVTAAAVAALQH 
               
               
                 37 
                 52 
                 46 
                 TSDVYDPQVASYLSAG 
               
               
                 442 
                 461 
                 447 
                 PDAAVIAAIEASAAAAVASQ 
               
               
                 212 
                 219 
                 216 
                 RCKIVINS 
               
               
                 131 
                 168 
                 156 
                 HQQLQHAYQQQQQLHQLGQLSQQLAQPHLSQHEHVRDA 
               
               
                 60 
                 87 
                 72 
                 NTALHHSNSVSYSASAAAAAAELQHRAE 
               
               
                 393 
                 419 
                 414 
                 YSELLGQLGQLSQQQSQQQQLHHIPQQ 
               
               
                 511 
                 521 
                 513 
                 DPNVQAHDHSH 
               
               
                 319 
                 325 
                 323 
                 RTLVEKP 
               
               
                 379 
                 388 
                 385 
                 QQQLQASGLP 
               
               
                 368 
                 377 
                 371 
                 QQQAAQLQQQ 
               
               
                 91 
                 126 
                 97 
                 RQQQLQQQELQHQQEQLQQYRQAQAQAQAQAQAQAQ 
               
               
                 427 
                 440 
                 439 
                 QSQQQPQQTPHGLD 
               
               
                 342 
                 358 
                 358 
                 QQQQQQQQQQQQQQQQQ 
               
               
                   
               
            
           
           
               
               
            
               
                 2. CPP1 
                   
               
               
                 MTTPLSSYSTTVTNHHPTFSFESLNSISSNNSTRNNQSNSVNSLLYFNSSGSSMVSSSSDAAPTSISTTTTS 
               
               
                   
               
               
                 TTSMTDASANADNQQVYTITKEDSINDINQKEQNSFSIQPNQTPTMLPTSSYTLQRPPGLHEYTSSISSISS 
               
               
                   
               
               
                 TSSNSTSTPVSPALINYSPKHSRKPNSLNLNRNMKNLSLNLHDSTNGYTSPLPKSTNSNQSRGNFIMDSPSK 
               
               
                   
               
               
                 KSTPVNRIGNNNGNDYINATLLQTPSITQTPTMPPPLSLAQGPPSSVGSESVYKFPPISNACLNYSAGDSDS 
               
               
                   
               
               
                 EVESMSMKQSAKNTIIPPMAPPFALQSKSSPLSTPPRLHSPLGVDRGLPISMSPIQSSLNQKFNNIALQTPL 
               
               
                   
               
               
                 NSSFSINNDEATNFNNKNNKNNNNNSTATTTITNTILSTPQNVRYNSKKFHPPEELQESTSINAYPNGPKNV 
               
               
                   
               
               
                 LNNLIYLYSDPVQGKIDINKFDLVINVAKECDNMSLQYMNQVPNQREYVYIPWSHNSNISKDLFQITNKIDQ 
               
               
                   
               
               
                 FFTNGRKILIHCQCGVSRSACVVVAFYMKKFQLGVNEAYELLKNGDQKYIDACDRICPNMNLIFELMEFGDK 
               
               
                   
               
               
                 LNNNEISTQQLLMNSPPTINL* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 MNLIFELMEFGDKLNN 
                 564 
                 0.95 
               
               
                 1 
                 QKYIDACDRICPNMNL 
                 551 
                 0.95 
               
               
                 2 
                 PALINYSPKHSRKPNS 
                 156 
                 0.94 
               
               
                 3 
                 PTSISTTTTSTTSMTD 
                 63 
                 0.93 
               
               
                 4 
                 SSSSDAAPTSISTTTT 
                 56 
                 0.92 
               
               
                 5 
                 ESVYKFPPISNACLNY 
                 266 
                 0.91 
               
               
                 6 
                 SPSKKSTPVNRIGNNN 
                 213 
                 0.89 
               
               
                 7 
                 STSINAYPNGPKNVLN 
                 419 
                 0.88 
               
               
                 7 
                 AGDSDSEVESMSMKQS 
                 283 
                 0.88 
               
               
                 8 
                 NSTATTTITNTILSTP 
                 385 
                 0.87 
               
               
                 8 
                 SISSISSTSSNSTSTP 
                 138 
                 0.87 
               
               
                 9 
                 SINNDEATNFNNKNNK 
                 365 
                 0.86 
               
               
                 10 
                 TQTPTMPPPLSLAQGP 
                 244 
                 0.85 
               
               
                 10 
                 YINATLLQTPSITQTP 
                 232 
                 0.85 
               
               
                 10 
                 PKHSRKPNSLNLNRNM 
                 163 
                 0.85 
               
               
                 11 
                 TNTILSTPQNVRYNSK 
                 393 
                 0.84 
               
               
                 11 
                 SMKQSAKNTIIPPMAP 
                 294 
                 0.84 
               
               
                 11 
                 PPISNACLNYSAGDSD 
                 272 
                 0.84 
               
               
                 11 
                 TTVTNHHPTFSFESLN 
                 10 
                 0.84 
               
               
                 12 
                 TSTTSMTDASANADNQ 
                 71 
                 0.83 
               
               
                 12 
                 QYMNQVPNQREYVYIP 
                 469 
                 0.83 
               
               
                 13 
                 PEELQESTSINAYPNG 
                 413 
                 0.82 
               
               
                 13 
                 SFSIQPNQTPTMLPTS 
                 107 
                 0.82 
               
               
                 14 
                 LGVNEAYELLKNGDQK 
                 537 
                 0.81 
               
               
                 14 
                 VVVAFYMKKFQLGVNE 
                 526 
                 0.81 
               
               
                 14 
                 GVDRGLPISMSPIQSS 
                 331 
                 0.81 
               
               
                 15 
                 GVSRSACVVVAFYMKK 
                 519 
                 0.80 
               
               
                 15 
                 LIHCQCGVSRSACVVV 
                 513 
                 0.80 
               
               
                 15 
                 QREYVYIPWSHNSNIS 
                 477 
                 0.80 
               
               
                 15 
                 PPRLHSPLGVDRGLPI 
                 323 
                 0.80 
               
               
                 15 
                 NSISSNNSTRNNQSNS 
                 25 
                 0.80 
               
               
                 16 
                 SGSSMVSSSSDAAPTS 
                 50 
                 0.79 
               
               
                 16 
                 KECDNMSLQYMNQVPN 
                 461 
                 0.79 
               
               
                 16 
                 VNRIGNNNGNDYINAT 
                 221 
                 0.79 
               
               
                 17 
                 QVYTITKEDSINDINQ 
                 87 
                 0.78 
               
               
                 17 
                 LMEFGDKLNNNEISTQ 
                 570 
                 0.78 
               
               
                 17 
                 VQGKIDINKFDLVINV 
                 444 
                 0.78 
               
               
                 17 
                 NQTPTMLPTSSYTLQR 
                 113 
                 0.78 
               
               
                 18 
                 KNTIIPPMAPPFALQS 
                 300 
                 0.77 
               
               
                 18 
                 DSTNGYTSPLPKSTNS 
                 187 
                 0.77 
               
               
                 18 
                 TSSYTLQRPPGLHEYT 
                 121 
                 0.77 
               
               
                 18 
                 NQKEQNSFSIQPNQTP 
                 101 
                 0.77 
               
               
                 19 
                 DLVINVAKECDNMSLQ 
                 454 
                 0.76 
               
               
                 19 
                 NSKKFHPPEELQESTS 
                 406 
                 0.76 
               
               
                 19 
                 LQSKSSPLSTPPRLHS 
                 313 
                 0.76 
               
               
                 19 
                 SSNSTSTPVSPALINY 
                 146 
                 0.76 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 511 
                 534 
                 528 
                 KILIHCQCGVSRSACVVVAFYMKK 
               
               
                 151 
                 164 
                 156 
                 STPVSPALINYSPK 
               
               
                 305 
                 348 
                 329 
                 PPMAPPFALQSKSSPLSTPPRLHSPLGVDRGLPISMSPIQSSLN 
               
               
                 453 
                 462 
                 458 
                 FDLVINVAKE 
               
               
                 41 
                 48 
                 44 
                 VNSLLYFN 
               
               
                 433 
                 447 
                 441 
                 LNNLIYLYSDPVQGK 
               
               
                 250 
                 282 
                 271 
                 PPPLSLAQGPPSSVGSESVYKFPPISNACLNYS 
               
               
                 553 
                 560 
                 559 
                 YIDACDRI 
               
               
                 477 
                 486 
                 483 
                 QREYVYIPWS 
               
               
                 356 
                 363 
                 357 
                 LQTPLNSS 
               
               
                 234 
                 242 
                 240 
                 NATLLQTPS 
               
               
                 584 
                 590 
                 585 
                 TQQLLMN 
               
               
                 86 
                 91 
                 89 
                 QQVYTI 
               
               
                 5 
                 15 
                 6 
                 LSSYSTTVTNH 
               
               
                 397 
                 403 
                 400 
                 LSTPQNV 
               
               
                 121 
                 144 
                 129 
                 TSSYTLQRPPGLHEYTSSISSISS 
               
               
                 193 
                 198 
                 195 
                 TSPLPK 
               
               
                 17 
                 26 
                 18 
                 PTFSFESLNS 
               
               
                 52 
                 60 
                 58 
                 SSMVSSSSD 
               
               
                 493 
                 499 
                 494 
                 KDLFQIT 
               
               
                   
               
            
           
           
               
               
            
               
                 3. CST20 
                   
               
               
                 MSILSENNPTQTSITDPNESSHLHNPELNSGTRVASGPGPGPEVESTPLAPPTEVMNTTSANTSSLSLGSPM 
               
               
                   
               
               
                 HEKIKQFDQDEVDTGETNDRTIESGSSDIDDSQQSHNNNNNNNNNESNPESSEADDEKTQGMPPRMPGTFNV 
               
               
                   
               
               
                 KGLHQGDDSDNEKQYTELTKSINKRTSKDSYSPGTLESPGTLNALETNNVSPAVIEEEQHTSSLEDLSLSLQ 
               
               
                   
               
               
                 HQNENARLSAPRSAPPQVSTSKTSSFHDMSSVISSSTSVHKIPSNPTSTRGSHLSSYKSTLDPGKPAQAAAP 
               
               
                   
               
               
                 PPPEIDIDNLLTKSELDSETDTLSSATNSPNLLRNDTLQGIPTRDDENIDDSPRQLSQNTSATSRNTSGTST 
               
               
                   
               
               
                 STVVKNSRSGTSKLTSTSTAHNQTAAITPIIPSHNKFHQQVINTNSTNSSSSLEPLGVGINSNSSPKNGKKR 
               
               
                   
               
               
                 KSGSKVRGVFSSMFGKNKSTSSSSSSNSGSNSHSQEVNIKISTPFNAKHLAHVGIDDNGSYTGLPIEWERLL 
               
               
                   
               
               
                 SASGITKKEQQQHPQAVMDIVAFYQDTSENPDDAAFKKFHFDNNKSSSSGWSNENTPPATPGGSNSGSGGGG 
               
               
                   
               
               
                 GGAPSSPHRTPPSSIIEKNNVEQKVITPSQSMPTKTESKQSENQHPHEDNATQYTPRTPTSHVQEGQFIPSR 
               
               
                   
               
               
                 PAPKPPSTPLSSMSVSHKTPSSQSLPRSDSQSDIRSSTPKSHQDISPSKIKIRSISSKSLKSMRSRKSGDKF 
               
               
                   
               
               
                 THIAPAPPPPSLPSIPKSKSHSASLSSQLRPATNGSTTAPIPASAAFGGENNALPRQRINEFKAHRAPPPPP 
               
               
                   
               
               
                 SASPAPPVPPAPPANLLSEQTSEIPQQRTAPSQALADVTAPTNIYEIQQTKYQEAQQKLREKKARELEEIQR 
               
               
                   
               
               
                 LREKNERQNRQQETGQNNADTASGGSNIAPPVPVPNKKPPSGSGGGRDAKQAALIAQKKREEKKRKNLQIIA 
               
               
                   
               
               
                 KLKTICNPGDPNELYVDLVKIGQGASGGVFLAHDVRDKSNIVAIKQMNLEQQPKKELIINEILVMKGSSHPN 
               
               
                   
               
               
                 IVNFIDSYLLKGDLWVIMEYMEGGSLTDIVTHSVMTEGQIGVVCRETLKGLKFLHSKGVIHRDIKSDNILLN 
               
               
                   
               
               
                 MDGNIKITDFGFCAQINEINSKRITMVGTPYWMAPEIVSRKEYGPKVDVWSLGIMIIEMLEGEPPYLNETPL 
               
               
                   
               
               
                 RALYLIATNGTPKLKDPESLSYDIRKFLAWCLQVDFNKRADADELLHDNFITECDDVSSLSPLVKIARLKKM 
               
               
                   
               
               
                 SESD* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 QTSITDPNESSHLHNP 
                 11 
                 0.98 
               
               
                 2 
                 GGSNIAPPVPVPNKKP 
                 888 
                 0.97 
               
               
                 3 
                 SSDIDDSQQSHNNNNN 
                 98 
                 0.96 
               
               
                 4 
                 NATQYTPRTPTSHVQE 
                 626 
                 0.95 
               
               
                 5 
                 LKTICNPGDPNELYVD 
                 938 
                 0.94 
               
               
                 6 
                 APEIVSRKEYGPKVDV 
                 1114 
                 0.93 
               
               
                 7 
                 QSENQHPHEDNATQYT 
                 616 
                 0.92 
               
               
                 7 
                 SGGGGGGAPSSPHRTP 
                 572 
                 0.92 
               
               
                 7 
                 PESSEADDEKTQGMPP 
                 121 
                 0.92 
               
               
                 7 
                 KGVIHRDIKSDNILLN 
                 1065 
                 0.92 
               
               
                 7 
                 LWVIMEYMEGGSLTDI 
                 1022 
                 0.92 
               
               
                 8 
                 LEEIQRLREKNERQNR 
                 859 
                 0.91 
               
               
                 8 
                 SRKSGDKFTHIAPAPP 
                 713 
                 0.91 
               
               
                 8 
                 GQFIPSRPAPKPPSTP 
                 642 
                 0.91 
               
               
                 8 
                 DTLQGIPTRDDENIDD 
                 324 
                 0.91 
               
               
                 9 
                 EILVMKGSSHPNIVNF 
                 997 
                 0.90 
               
               
                 9 
                 KSNIVAIKQMNLEQQP 
                 974 
                 0.90 
               
               
                 9 
                 ALIAQKKREEKKRKNL 
                 917 
                 0.90 
               
               
                 9 
                 KPPSGSGGGRDAKQAA 
                 902 
                 0.90 
               
               
                 9 
                 PQQRTAPSQALADVTA 
                 817 
                 0.90 
               
               
                 9 
                 ALPRQRINEFKAHRAP 
                 773 
                 0.90 
               
               
                 9 
                 LSSYKSTLDPGKPAQA 
                 270 
                 0.90 
               
               
                 9 
                 PGTLESPGTLNALETN 
                 177 
                 0.90 
               
               
                 9 
                 FLAWCLQVDFNKRADA 
                 1179 
                 0.90 
               
               
                 10 
                 HKTPSSQSLPRSDSQS 
                 665 
                 0.89 
               
               
                 10 
                 SSPHRTPPSSIIEKNN 
                 581 
                 0.89 
               
               
                 10 
                 KRTSKDSYSPGTLESP 
                 168 
                 0.89 
               
               
                 10 
                 EKTQGMPPRMPGTFNV 
                 129 
                 0.89 
               
               
                 10 
                 IMIIEMLEGEPPYLNE 
                 1134 
                 0.89 
               
               
                 10 
                 ITMVGTPYWMAPEIVS 
                 1104 
                 0.89 
               
               
                 11 
                 EQKVITPSQSMPTKTE 
                 598 
                 0.88 
               
               
                 11 
                 SSSSGWSNENTPPATP 
                 550 
                 0.88 
               
               
                 11 
                 GTRVASGPGPGPEVES 
                 31 
                 0.88 
               
               
                 12 
                 TAPIPASAAFGGENNA 
                 758 
                 0.87 
               
               
                 12 
                 PKPPSTPLSSMSVSHK 
                 651 
                 0.87 
               
               
                 12 
                 LGVGINSNSSPKNGKK 
                 416 
                 0.87 
               
               
                 12 
                 DTLSSATNSPNLLRND 
                 309 
                 0.87 
               
               
                 12 
                 DVSSLSPLVKIARLKK 
                 1208 
                 0.87 
               
               
                 13 
                 THIAPAPPPPSLPSIP 
                 721 
                 0.86 
               
               
                 13 
                 MSSVISSSTSVHKIPS 
                 245 
                 0.86 
               
               
                 14 
                 AHRAPPPPPSASPAPP 
                 784 
                 0.85 
               
               
                 14 
                 SSIIEKNNVEQKVITP 
                 589 
                 0.85 
               
               
                 14 
                 AITPIIPSHNKFHQQV 
                 386 
                 0.85 
               
               
                 14 
                 SGTSKLTSTSTAHNQT 
                 369 
                 0.85 
               
               
                 14 
                 STRGSHLSSYKSTLDP 
                 264 
                 0.85 
               
               
                 15 
                 QNRQQETGQNNADTAS 
                 872 
                 0.84 
               
               
                 15 
                 AHVGIDDNGSYTGLPI 
                 483 
                 0.84 
               
               
                 15 
                 SRNTSGTSTSTVVKNS 
                 352 
                 0.84 
               
               
                 15 
                 DENIDDSPRQLSQNTS 
                 334 
                 0.84 
               
               
                 15 
                 KGLHQGDDSDNEKQYT 
                 145 
                 0.84 
               
               
                 16 
                 DIVAFYQDTSENPDDA 
                 523 
                 0.83 
               
               
                 16 
                 SGSNSHSQEVNIKIST 
                 460 
                 0.83 
               
               
                 16 
                 PEVESTPLAPPTEVMN 
                 42 
                 0.83 
               
               
                 16 
                 STVVKNSRSGTSKLTS 
                 361 
                 0.83 
               
               
                 17 
                 GGVFLAHDVRDKSNIV 
                 963 
                 0.82 
               
               
                 17 
                 GETNDRTIESGSSDID 
                 87 
                 0.82 
               
               
                 17 
                 PPPSASPAPPVPPAPP 
                 790 
                 0.82 
               
               
                 17 
                 AFGGENNALPRQRINE 
                 766 
                 0.82 
               
               
                 17 
                 NKSTSSSSSSNSGSNS 
                 449 
                 0.82 
               
               
                 18 
                 DDAAFKKFHFDNNKSS 
                 536 
                 0.81 
               
               
                 18 
                 GKPAQAAAPPPPEIDI 
                 280 
                 0.81 
               
               
                 18 
                 THSVMTEGQIGVVCRE 
                 1039 
                 0.81 
               
               
                 19 
                 SQSDIRSSTPKSHQDI 
                 678 
                 0.80 
               
               
                 19 
                 PRTPTSHVQEGQFIPS 
                 632 
                 0.80 
               
               
                 19 
                 EKQYTELTKSINKRTS 
                 156 
                 0.80 
               
               
                 20 
                 QDEVDTGETNDRTIES 
                 81 
                 0.79 
               
               
                 20 
                 TSSLEDLSLSLQHQNE 
                 205 
                 0.79 
               
               
                 21 
                 EQTSEIPQQRTAPSQA 
                 811 
                 0.78 
               
               
                 21 
                 SPRQLSQNTSATSRNT 
                 340 
                 0.78 
               
               
                 22 
                 SSMSVSHKTPSSQSLP 
                 659 
                 0.77 
               
               
                 22 
                 EVNIKISTPFNAKHLA 
                 468 
                 0.77 
               
               
                 22 
                 PRMPGTFNVKGLHQGD 
                 136 
                 0.77 
               
               
                 22 
                 GVVCRETLKGLKFLHS 
                 1049 
                 0.77 
               
               
                 23 
                 LPSIPKSKSHSASLSS 
                 732 
                 0.76 
               
               
                 23 
                 QSLPRSDSQSDIRSST 
                 671 
                 0.76 
               
               
                 23 
                 KVRGVFSSMFGKNKST 
                 437 
                 0.76 
               
               
                 23 
                 SSTSVHKIPSNPTSTR 
                 251 
                 0.76 
               
               
                 23 
                 NARLSAPRSAPPQVST 
                 221 
                 0.76 
               
               
                 23 
                 ESLSYDIRKFLAWCLQ 
                 1170 
                 0.76 
               
               
                 24 
                 KIKQFDQDEVDTGETN 
                 75 
                 0.75 
               
               
                 24 
                 SSLSLGSPMHEKIKQF 
                 64 
                 0.75 
               
               
                 24 
                 ASGITKKEQQQHPQAV 
                 506 
                 0.75 
               
               
                 24 
                 SSSSLEPLGVGINSNS 
                 409 
                 0.75 
               
               
                 24 
                 LYLIATNGTPKLKDPE 
                 1155 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 1171 
                 1187 
                 1183 
                 SLSYDIRKFLAWCLQVD 
               
               
                 949 
                 958 
                 953 
                 ELYVDLVKIG 
               
               
                 892 
                 901 
                 895 
                 IAPPVPVPNK 
               
               
                 962 
                 972 
                 968 
                 SGGVFLAHDVR 
               
               
                 1047 
                 1055 
                 1049 
                 QIGVVCRET 
               
               
                 1203 
                 1221 
                 1215 
                 ITECDDVSSLSPLVKIARL 
               
               
                 1152 
                 1159 
                 1155 
                 LRALYLIA 
               
               
                 479 
                 487 
                 484 
                 AKHLAHVGI 
               
               
                 195 
                 201 
                 197 
                 SPAVIEE 
               
               
                 205 
                 217 
                 214 
                 TSSLEDLSLSLQH 
               
               
                 932 
                 944 
                 935 
                 LQIIAKLKTICNP 
               
               
                 1035 
                 1041 
                 1039 
                 TDIVTHS 
               
               
                 1007 
                 1027 
                 1015 
                 PNIVNFIDSYLLKGDLWVIME 
               
               
                 785 
                 811 
                 801 
                 HRAPPPPPSASPAPPVPPAPPANLLSE 
               
               
                 516 
                 529 
                 524 
                 QHPQAVMDIVAFYQ 
               
               
                 1124 
                 1135 
                 1129 
                 GPKVDVWSLGIM 
               
               
                 995 
                 1003 
                 997 
                 INEILVMKG 
               
               
                 1058 
                 1071 
                 1065 
                 GLKFLHSKGVIHRD 
               
               
                 1090 
                 1096 
                 1093 
                 FGFCAQI 
               
               
                 386 
                 403 
                 399 
                 AITPIIPSHNKFHQQVIN 
               
               
                 412 
                 419 
                 415 
                 SLEPLGVG 
               
               
                 245 
                 259 
                 257 
                 MSSVISSSTSVHKIP 
               
               
                 823 
                 831 
                 827 
                 PSQALADVT 
               
               
                 438 
                 444 
                 441 
                 VRGVFSS 
               
               
                 915 
                 921 
                 918 
                 QAALIAQ 
               
               
                 598 
                 604 
                 600 
                 EQKVITP 
               
               
                 721 
                 750 
                 732 
                 THIAPAPPPPSLPSIPKSKSHSASLSSQLR 
               
               
                 224 
                 237 
                 232 
                 LSAPRSAPPQVSTS 
               
               
                 45 
                 53 
                 52 
                 ESTPLAPPT 
               
               
                 636 
                 668 
                 660 
                 TSHVQEGQFIPSRPAPKPPSTPLSSMSVSHKTP 
               
               
                 360 
                 366 
                 362 
                 TSTVVKN 
               
               
                 976 
                 982 
                 980 
                 NIVAIKQ 
               
               
                 759 
                 766 
                 764 
                 APIPASAA 
               
               
                 267 
                 276 
                 271 
                 GSHLSSYKST 
               
               
                 63 
                 70 
                 68 
                 TSSLSLGS 
               
               
                 282 
                 293 
                 288 
                 PAQAAAPPPPEI 
               
               
                 670 
                 676 
                 671 
                 SQSLPRS 
               
               
                 20 
                 26 
                 25 
                 SSHLHNP 
               
               
                 1114 
                 1121 
                 1117 
                 APEIVSRK 
               
               
                 690 
                 707 
                 705 
                 HQDISPSKIKIRSISSKS 
               
               
                 581 
                 591 
                 589 
                 SSPHRTPPSSI 
               
               
                 466 
                 472 
                 472 
                 SQEVNIK 
               
               
                 1143 
                 1149 
                 1149 
                 EPPYLNE 
               
               
                 836 
                 842 
                 839 
                 IYEIQQT 
               
               
                   
               
            
           
           
               
               
            
               
                 4. CHK1 
                   
               
               
                 MSMNFFNSSEPARDHKPDQEKETVMTTEHYEFERPDVKAIRNFKFFRSDETETKKGPNLHISDLSPLESQSV 
               
               
                   
               
               
                 PPSALSLNHSIIPDQYERRQDTPDPIHTPEISLSDYLYDQTLSPQGFDNSRENFNIHKTIASLFEDNSSVVS 
               
               
                   
               
               
                 QESTDDTKTTLSSETCDSFSLNNASYLTNINFVQNHLQYLSQNVLGNRTSNSLPPSSSSQIDFDASNLTPDS 
               
               
                   
               
               
                 IPGYILNKKLGSVHQSTDSVYNAIKIPQNEEYNCCTKASASQNPTNLNSKVIVRLSPNIFQNLSLSRFLNEW 
               
               
                   
               
               
                 YILSGKHSSKEHQIWSNESLTNEYVQDKTIPTFDKESARFRPTLPINIPGILYPQEIINFCVNSHDYPLEHP 
               
               
                   
               
               
                 SQSTDQKRFAMVYQDNDYKTFKELSMFTLHELQTRQGSYSSNESRRKSSSGFNIGVNATTTEAGSLESFSNL 
               
               
                   
               
               
                 MQNHHLGATSTNGDPFHSKLAKFEYGVSKSPMKLIEILTDIMRVVETISVIHELGFVHNGLTSSNLLKSEKN 
               
               
                   
               
               
                 VRDIKITGWGFAFSFTENCSQGYRNKHLAQVQDLIPYMAPEVLAITNSVVDYRSDFYSLGVIMYELVLGILP 
               
               
                   
               
               
                 FKNSNPQKLIRMHTFENPIAPSALAPGWISEKLSGVIMKLLEKHPHNRYTDCHSLLHDLIEVKNMYISKLLD 
               
               
                   
               
               
                 SGETIPNSNLNLSDRQYYLTKENLLHPEKMGITPVLGLKESFIGRRDFLQNVTEVYNNSKNGIDLLFISGES 
               
               
                   
               
               
                 GRGKTIILQDLRAAAVLKQDFYYSWKFSFFGADTHVYRFLVEGVQKIITQILNSSEEIQNTWRDVILTHIPI 
               
               
                   
               
               
                 DLSILFYLIPELKVLLGKKYTSIYKHKIGMGMLKRSFKEDQTSRLEIKLRQILKEFFKLVAKQGLSIFLDDV 
               
               
                   
               
               
                 QWCSEESWRLLCDVLDFDSSGEVRESYNIKIVVCYALNADHLENVNIEHKKISFCQYAKQSHLNLREFSIPH 
               
               
                   
               
               
                 IPLEDAIEFLCEPYTRSHDHECNSKKSDVIANLNCTNEYQQNTCKVIPSIIQELYQSSEGNVLLLIFLTRMT 
               
               
                   
               
               
                 KLSGKVPFQRFSVKNSYLYDHLSNSNYGTTRKEILTNYLNMGTNSDTRALLKVAALISNGSGFFFSDLIVAT 
               
               
                   
               
               
                 DLPMAEAFQLLQICIHSRIIVPTSTYYKIPMDLIASDQTPFDLTDDNIWKLATLCSYKFYHDSICTHIIKEL 
               
               
                   
               
               
                 NASGEFKELSRLCGLRFYNTITKERLLNIGGYLQMATHFRNSYEVAGPEENEKYVEVLVQAGRYAISTYNMK 
               
               
                   
               
               
                 LSQWFFNVVGELVYNLDSKTQLKSVLTIAENHFNSREFEQCLSVVENAQRKFGFDRLIFSIQIVRCKIELGD 
               
               
                   
               
               
                 YDEAHRIAIECLKELGVPLDDDDEYTSENSLETCLGKIPLSVADIRGILKIKRCKNSRTLLMYQLISELIVL 
               
               
                   
               
               
                 FKLQGKDKVRRFLTAYAMSQIHTQGSSPYCAVILIDFAQSFVNETTTSGMLKAKELSIVMLSLINRAPEISL 
               
               
                   
               
               
                 SYVQSIYEYYFSCHAVFFESIEKMSDLIHPGNASSHCTRSSYYSSFHLIVNVSKIFFSCMNGESFKMFSTFK 
               
               
                   
               
               
                 CKSYLTGDPQMPEMDNFLYDSEMLLAGHSELNEFMRKYQSFNQTSVGKFCYYLIVLLVMSREHRFDEAADLV 
               
               
                   
               
               
                 LKVLEDLSEKLPVSFLHHQYYLICGKVFAYHQTKTPESEEQVERILARQFERYELWASTNKPTLLPRYLLLS 
               
               
                   
               
               
                 TYKQIRENHVDKLEILDSFEEALQTAHKFHNVYDMCWINLECARWLISINQKRHRISRMVKQGLKILRSLEL 
               
               
                   
               
               
                 NNHLRLAEFEFDEYIEDEDHRNKWAGLTNNPTLDTVTTWQQQNMPDKVSPCNDKQLVHGKQFGKKEFDSHLL 
               
               
                   
               
               
                 RLHFDGQYTGLDLNSAIRECLAISEALDENSILTKLMASAIKYSGATYGVIVTKKNQETPFLRTIGSQHNIH 
               
               
                   
               
               
                 TLNNMPISDDICPAQLIRHVLHTGETVNKAHDHIGFANKFENEYFQTTDKKYSVVCLPLKSSLGLFGALYLE 
               
               
                   
               
               
                 GSDGDFGHEDLFNERKCDLLQLFCTQAAVALGKERLLLQMELAKMAAEDATDEKASFLANMSHEIRTPFNSL 
               
               
                   
               
               
                 LSFAIFLLDTKLDSTQREYVEAIQSSAMITLNIIDGILAFSKIEHGSFTLENAPFSLNDCIETAIQVSGETI 
               
               
                   
               
               
                 LNDQIELVFCNNCPEIEFVVGDLTRFRQIVINLVGNAIKFTTKGHVLISCDSRKITDDRFEINVSVEDSGIG 
               
               
                   
               
               
                 ISKKSQNKVFGAFSQVDGSARREYGGSGLGLAISKKLTELMGGTIRFESEEGIGTTFYVSVIMDAKEYSSPP 
               
               
                   
               
               
                 FSLNKKCLIYSQHCLTAKSISNMLNYFGSTVKVTNQKSEFSTSVQANDIIFVDRGMEPDVSCKTKIIPIDPK 
               
               
                   
               
               
                 PFKRNKLISILKEQPSLPTKVFGNNKSNLSKQYPLRILLAEDNLLNYKVCLKHLDKLGYKADHAKDGVVVLD 
               
               
                   
               
               
                 KCKELLEKDEKYDVILMDIQMPRKDGITATRDLKTLFHTQKKESWLPVIVALTANVAGDDKKRCLEEGMFDF 
               
               
                   
               
               
                 ITKPILPDELRRILTKVGETVNM* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 TETKKGPNLHISDLSP 
                 51 
                 0.96 
               
               
                 2 
                 LMDIQMPRKDGITATR 
                 2392 
                 0.93 
               
               
                 2 
                 SVHQSTDSVYNAIKIP 
                 228 
                 0.93 
               
               
                 2 
                 GGTIRFESEEGIGTTF 
                 2202 
                 0.93 
               
               
                 3 
                 FLCEPYTRSHDHECNS 
                 945 
                 0.92 
               
               
                 3 
                 IGMGMLKRSFKEDQTS 
                 820 
                 0.92 
               
               
                 3 
                 EHYEFERPDVKAIRNF 
                 28 
                 0.92 
               
               
                 4 
                 HSSKEHQIWSNESLTN 
                 295 
                 0.91 
               
               
                 4 
                 SDLIVATDLPMAEAFQ 
                 1074 
                 0.91 
               
               
                 5 
                 HSIIPDQYERRQDTPD 
                 81 
                 0.90 
               
               
                 5 
                 PPSSSSQIDFDASNLT 
                 198 
                 0.90 
               
               
                 5 
                 VILIDFAQSFVNETTT 
                 1400 
                 0.90 
               
               
                 5 
                 PEISLSDYLYDQTLSP 
                 101 
                 0.90 
               
               
                 6 
                 CSEESWRLLCDVLDFD 
                 867 
                 0.89 
               
               
                 6 
                 ESRRKSSSGFNIGVNA 
                 403 
                 0.89 
               
               
                 6 
                 CLAISEALDENSILTK 
                 1820 
                 0.89 
               
               
                 7 
                 KESFIGRRDFLQNVTE 
                 687 
                 0.88 
               
               
                 7 
                 RQGSYSSNESRRKSSS 
                 395 
                 0.88 
               
               
                 7 
                 AKEYSSPPFSLNKKCL 
                 2225 
                 0.88 
               
               
                 7 
                 FDEYIEDEDHRNKWAG 
                 1739 
                 0.88 
               
               
                 7 
                 KSYLTGDPQMPEMDNF 
                 1514 
                 0.88 
               
               
                 7 
                 CTRSSYYSSFHLIVNV 
                 1477 
                 0.88 
               
               
                 8 
                 PGWISEKLSGVIMKLL 
                 602 
                 0.87 
               
               
                 8 
                 QKLIRMHTFENPIAPS 
                 583 
                 0.87 
               
               
                 8 
                 KETVMTTEHYEFERPD 
                 21 
                 0.87 
               
               
                 8 
                 AFSKIEHGSFTLENAP 
                 2055 
                 0.87 
               
               
                 8 
                 QREYVEAIQSSAMITL 
                 2032 
                 0.87 
               
               
                 8 
                 TWQQQNMPDKVSPCND 
                 1766 
                 0.87 
               
               
                 8 
                 NSYEVAGPEENEKYVE 
                 1193 
                 0.87 
               
               
                 8 
                 DLIASDQTPFDLTDDN 
                 1112 
                 0.87 
               
               
                 8 
                 PTSTYYKIPMDLIASD 
                 1102 
                 0.87 
               
               
                 9 
                 HDHECNSKKSDVIANL 
                 954 
                 0.86 
               
               
                 9 
                 HDLIEVKNMYISKLLD 
                 633 
                 0.86 
               
               
                 9 
                 DLIPYMAPEVLAITNS 
                 537 
                 0.86 
               
               
                 9 
                 HPSQSTDQKRFAMVYQ 
                 359 
                 0.86 
               
               
                 9 
                 DKTIPTFDKESARFRP 
                 315 
                 0.86 
               
               
                 9 
                 VSVIMDAKEYSSPPFS 
                 2219 
                 0.86 
               
               
                 9 
                 DSRKITDDRFEINVSV 
                 2139 
                 0.86 
               
               
                 9 
                 HDHIGFANKFENEYFQ 
                 1903 
                 0.86 
               
               
                 9 
                 HRNKWAGLTNNPTLDT 
                 1748 
                 0.86 
               
               
                 9 
                 PGNASSHCTRSSYYSS 
                 1470 
                 0.86 
               
               
                 9 
                 VQSIYEYYFSCHAVFF 
                 1443 
                 0.86 
               
               
                 9 
                 RFSVKNSYLYDHLSNS 
                 1018 
                 0.86 
               
               
                 10 
                 LHPEKMGITPVLGLKE 
                 673 
                 0.85 
               
               
                 10 
                 QPSLPTKVFGNNKSNL 
                 2318 
                 0.85 
               
               
                 10 
                 EGIGTTFYVSVIMDAK 
                 2211 
                 0.85 
               
               
                 10 
                 DGDFGHEDLFNERKCD 
                 1947 
                 0.85 
               
               
                 10 
                 AQLIRHVLHTGETVNK 
                 1886 
                 0.85 
               
               
                 10 
                 SAIKYSGATYGVIVTK 
                 1839 
                 0.85 
               
               
                 10 
                 HGKQFGKKEFDSHLLR 
                 1786 
                 0.85 
               
               
                 10 
                 AGHSELNEFMRKYQSF 
                 1538 
                 0.85 
               
               
                 11 
                 VNSHDYPLEHPSQSTD 
                 350 
                 0.84 
               
               
                 11 
                 NEEYNCCTKASASQNP 
                 245 
                 0.84 
               
               
                 11 
                 KKRCLEEGMFDFITKP 
                 2437 
                 0.84 
               
               
                 11 
                 LISINQKRHRISRMVK 
                 1702 
                 0.84 
               
               
                 11 
                 ASTNKPTLLPRYLLLS 
                 1641 
                 0.84 
               
               
                 11 
                 SVLTIAENHFNSREFE 
                 1248 
                 0.84 
               
               
                 12 
                 SSEEIQNTWRDVILTH 
                 774 
                 0.83 
               
               
                 12 
                 SGRGKTIILQDLRAAA 
                 720 
                 0.83 
               
               
                 12 
                 LSDRQYYLTKENLLHP 
                 660 
                 0.83 
               
               
                 12 
                 IPGILYPQEIINFCVN 
                 336 
                 0.83 
               
               
                 12 
                 KELLEKDEKYDVILMD 
                 2379 
                 0.83 
               
               
                 12 
                 YNAIKIPQNEEYNCCT 
                 237 
                 0.83 
               
               
                 12 
                 KIIPIDPKPFKRNKLI 
                 2297 
                 0.83 
               
               
                 12 
                 IIFVDRGMEPDVSCKT 
                 2281 
                 0.83 
               
               
                 12 
                 SVVENAQRKFGFDRLI 
                 1267 
                 0.83 
               
               
                 12 
                 QAGRYAISTYNMKLSQ 
                 1212 
                 0.83 
               
               
                 12 
                 ATLCSYKFYHDSICTH 
                 1132 
                 0.83 
               
               
                 12 
                 TLSPQGFDNSRENFNI 
                 113 
                 0.83 
               
               
                 12 
                 TRKEILTNYLNMGTNS 
                 1038 
                 0.83 
               
               
                 13 
                 PSIIQELYQSSEGNVL 
                 984 
                 0.82 
               
               
                 13 
                 SSEPARDHKPDQEKET 
                 8 
                 0.82 
               
               
                 13 
                 EVLAITNSVVDYRSDF 
                 545 
                 0.82 
               
               
                 13 
                 NCSQGYRNKHLAQVQD 
                 522 
                 0.82 
               
               
                 13 
                 GSARREYGGSGLGLAI 
                 2178 
                 0.82 
               
               
                 13 
                 KGHVLISCDSRKITDD 
                 2131 
                 0.82 
               
               
                 13 
                 LYLEGSDGDFGHEDLF 
                 1941 
                 0.82 
               
               
                 14 
                 EFSIPHIPLEDAIEFL 
                 931 
                 0.81 
               
               
                 14 
                 KIITQILNSSEEIQNT 
                 766 
                 0.81 
               
               
                 14 
                 DQKRFAMVYQDNDYKT 
                 365 
                 0.81 
               
               
                 14 
                 RFLNEWYILSGKHSSK 
                 283 
                 0.81 
               
               
                 14 
                 AFSQVDGSARREYGGS 
                 2172 
                 0.81 
               
               
                 14 
                 ERYELWASTNKPTLLP 
                 1635 
                 0.81 
               
               
                 14 
                 TLSSETCDSFSLNNAS 
                 154 
                 0.81 
               
               
                 15 
                 LGFVHNGLTSSNLLKS 
                 486 
                 0.80 
               
               
                 15 
                 TISVIHELGFVHNGLT 
                 479 
                 0.80 
               
               
                 15 
                 GATSTNGDPFHSKLAK 
                 439 
                 0.80 
               
               
                 15 
                 VKAIRNFKFFRSDETE 
                 37 
                 0.80 
               
               
                 15 
                 GYKADHAKDGVVVLDK 
                 2362 
                 0.80 
               
               
                 15 
                 SFLANMSHEIRTPFNS 
                 2000 
                 0.80 
               
               
                 15 
                 FFSCMNGESFKMFSTF 
                 1496 
                 0.80 
               
               
                 15 
                 SVVSQESTDDTKTTLS 
                 141 
                 0.80 
               
               
                 15 
                 AMSQIHTQGSSPYCAV 
                 1385 
                 0.80 
               
               
                 15 
                 GGYLQMATHFRNSYEV 
                 1182 
                 0.80 
               
               
                 15 
                 FQLLQICIHSRIIVPT 
                 1088 
                 0.80 
               
               
                 16 
                 YERRQDTPDPIHTPEI 
                 88 
                 0.79 
               
               
                 16 
                 NSKVIVRLSPNIFQNL 
                 264 
                 0.79 
               
               
                 16 
                 LPVIVALTANVAGDDK 
                 2422 
                 0.79 
               
               
                 16 
                 VERILARQFERYELWA 
                 1626 
                 0.79 
               
               
                 16 
                 HKTIASLFEDNSSVVS 
                 129 
                 0.79 
               
               
                 17 
                 VRDIKITGWGFAFSFT 
                 505 
                 0.78 
               
               
                 17 
                 YGVSKSPMKLIEILTD 
                 457 
                 0.78 
               
               
                 17 
                 EFEQCLSVVENAQRKF 
                 1261 
                 0.78 
               
               
                 18 
                 DFLQNVTEVYNNSKNG 
                 695 
                 0.77 
               
               
                 18 
                 MYELVLGILPFKNSNP 
                 567 
                 0.77 
               
               
                 18 
                 RFRPTLPINIPGILYP 
                 327 
                 0.77 
               
               
                 18 
                 TPDSIPGYILNKKLGS 
                 213 
                 0.77 
               
               
                 18 
                 FHNVYDMCWINLECAR 
                 1685 
                 0.77 
               
               
                 18 
                 SFVNETTTSGMLKAKE 
                 1408 
                 0.77 
               
               
                 19 
                 PQEIINFCVNSHDYPL 
                 342 
                 0.76 
               
               
                 19 
                 HQTKTPESEEQVERIL 
                 1615 
                 0.76 
               
               
                 19 
                 SGMLKAKELSIVMLSL 
                 1416 
                 0.76 
               
               
                 19 
                 RCKIELGDYDEAHRIA 
                 1289 
                 0.76 
               
               
                 20 
                 SGEVRESYNIKIVVCY 
                 884 
                 0.75 
               
               
                 20 
                 EFVVGDLTRFRQIVIN 
                 2105 
                 0.75 
               
               
                 20 
                 KFENEYFQTTDKKYSV 
                 1911 
                 0.75 
               
               
                 20 
                 ENSILTKLMASAIKYS 
                 1829 
                 0.75 
               
               
                 20 
                 GVPLDDDDEYTSENSL 
                 1312 
                 0.75 
               
               
                 20 
                 DYLYDQTLSPQGFDNS 
                 107 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 1558 
                 1572 
                 1567 
                 VGKFCYYLIVLLVMS 
               
               
                 892 
                 904 
                 898 
                 NIKIVVCYALNAD 
               
               
                 1923 
                 1944 
                 1928 
                 KYSVVCLPLKSSLGLFGALYLE 
               
               
                 996 
                 1005 
                 1001 
                 GNVLLLIFLT 
               
               
                 2369 
                 2381 
                 2375 
                 KDGVVVLDKCKEL 
               
               
                 1394 
                 1410 
                 1400 
                 SSPYCAVILIDFAQSFV 
               
               
                 2421 
                 2431 
                 2425 
                 WLPVIVALTAN 
               
               
                 1206 
                 1219 
                 1209 
                 YVEVLVQAGRYAIS 
               
               
                 1087 
                 1118 
                 1093 
                 AFQLLQICIHSRIIVPTSTYYKIPMDLIASDQ 
               
               
                 1580 
                 1617 
                 1585 
                 AADLVLKVLEDLSEKLPVSFLHHQYYLICG 
               
               
                   
                   
                   
                 KVFAYHQT 
               
               
                 1356 
                 1371 
                 1368 
                 LLMYQLISELIVLFKL 
               
               
                 1262 
                 1271 
                 1266 
                 FEQCLSVVEN 
               
               
                 1226 
                 1240 
                 1235 
                 SQWFFNVVGELVYNL 
               
               
                 873 
                 881 
                 876 
                 RLLCDVLDF 
               
               
                 2349 
                 2366 
                 2355 
                 LNYKVCLKHLDKLGYKAD 
               
               
                 752 
                 773 
                 758 
                 ADTHVYRFLVEGVQKIITQILN 
               
               
                 1437 
                 1459 
                 1453 
                 EISLSYVQSIYEYYFSCHAVFFE 
               
               
                 530 
                 577 
                 573 
                 KHLAQVQDLIPYMAPEVLAITNSVVDYRSDFYSLGVIMY 
               
               
                   
                   
                   
                 ELVLGILPF 
               
               
                 1056 
                 1066 
                 1061 
                 RALLKVAALIS 
               
               
                 2131 
                 2141 
                 2135 
                 KGHVLISCDSR 
               
               
                 1961 
                 1985 
                 1966 
                 CDLLQLFCTQAAVALGKERLLLQME 
               
               
                 784 
                 811 
                 797 
                 DVILTHIPIDLSILFYLIPELKVLLGKK 
               
               
                 2090 
                 2101 
                 2095 
                 NDQIELVFCNNC 
               
               
                 1474 
                 1499 
                 1489 
                 SSHCTRSSYYSSFHLIVNVSKIFFSC 
               
               
                 1881 
                 1896 
                 1891 
                 DDICPAQLIRHVLHTG 
               
               
                 264 
                 274 
                 270 
                 NSKVIVRLSPN 
               
               
                 2114 
                 2125 
                 2119 
                 FRQIVINLVGNA 
               
               
                 2228 
                 2250 
                 2242 
                 YSSPPFSLNKKCLIYSQHCLTAK 
               
               
                 977 
                 993 
                 983 
                 QNTCKVIPSIIQELYQS 
               
               
                 1646 
                 1659 
                 1651 
                 PTLLPRYLLLSTYK 
               
               
                 2216 
                 2224 
                 2219 
                 TFYVSVIMD 
               
               
                 449 
                 492 
                 479 
                 HSKLAKFEYGVSKSPMKLIEILTDIMRVVETISVIHELG 
               
               
                   
                   
                   
                 FVHNG 
               
               
                 1131 
                 1152 
                 1134 
                 LATLCSYKFYHDSICTHIIKEL 
               
               
                 1421 
                 1434 
                 1429 
                 AKELSIVMLSLINR 
               
               
                 625 
                 641 
                 630 
                 YTDCHSLLHDLIEVKNM 
               
               
                 2334 
                 2346 
                 2340 
                 SKQYPLRILLAED 
               
               
                 1279 
                 1295 
                 1287 
                 DRLIFSIQIVRCKIELG 
               
               
                 1302 
                 1316 
                 1310 
                 RIAIECLKELGVPLD 
               
               
                 725 
                 747 
                 734 
                 TIILQDLRAAAVLKQDFYYSWKF 
               
               
                 1327 
                 1350 
                 1333 
                 LETCLGKIPLSVADIRGILKIKRC 
               
               
                 1833 
                 1854 
                 1849 
                 LTKLMASAIKYSGATYGVIVTK 
               
               
                 1796 
                 1806 
                 1801 
                 DSHLLRLHFDG 
               
               
                 1161 
                 1168 
                 1164 
                 LSRLCGLR 
               
               
                 2014 
                 2027 
                 2019 
                 NSLLSFAIFLLDTK 
               
               
                 914 
                 950 
                 919 
                 KKISFCQYAKQSHLNLREFSIPHIPLEDAIEFLCEPY 
               
               
                 1245 
                 1253 
                 1249 
                 QLKSVLTIA 
               
               
                 680 
                 689 
                 683 
                 ITPVLGLKES 
               
               
                 1071 
                 1082 
                 1079 
                 FFFSDLIVATDL 
               
               
                 58 
                 86 
                 74 
                 NLHISDLSPLESQSVPPSALSLNHSIIPD 
               
               
                 177 
                 188 
                 186 
                 VQNHLQYLSQNV 
               
               
                 329 
                 360 
                 347 
                 RPTLPINIPGILYPQEIINFCVNSHDYPLEHP 
               
               
                 963 
                 969 
                 968 
                 SDVIANL 
               
               
                 1817 
                 1826 
                 1823 
                 IRECLAISEA 
               
               
                 1011 
                 1030 
                 1027 
                 SGKVPFQRFSVKNSYLYDHL 
               
               
                 2103 
                 2111 
                 2104 
                 EIEFVVGDL 
               
               
                 248 
                 255 
                 253 
                 YNCCTKAS 
               
               
                 1510 
                 1519 
                 1514 
                 TFKCKSYLTG 
               
               
                 711 
                 717 
                 714 
                 IDLLFIS 
               
               
                 838 
                 868 
                 854 
                 EIKLRQILKEFFKLVAKQGLSIFLDDVQWCS 
               
               
                 1685 
                 1705 
                 1695 
                 FHNVYDMCWINLECARWLISI 
               
               
                 276 
                 284 
                 282 
                 FQNLSLSRF 
               
               
                 1775 
                 1788 
                 1776 
                 KVSPCNDKQLVHGK 
               
               
                 2291 
                 2304 
                 2295 
                 DVSCKTKIIPIDPK 
               
               
                 1717 
                 1726 
                 1723 
                 KQGLKILRSL 
               
               
                 96 
                 117 
                 107 
                 DPIHTPEISLSDYLYDQTLSPQ 
               
               
                 1666 
                 1674 
                 1669 
                 VDKLEILDS 
               
               
                 2311 
                 2325 
                 2313 
                 LISILKEQPSLPTKV 
               
               
                 596 
                 603 
                 597 
                 APSALAPG 
               
               
                 140 
                 146 
                 143 
                 SSVVSQE 
               
               
                 217 
                 242 
                 219 
                 IPGYILNKKLGSVHQSTDSVYNAIKI 
               
               
                 607 
                 620 
                 614 
                 EKLSGVIMKLLEKH 
               
               
                 2050 
                 2059 
                 2056 
                 IDGILAFSKI 
               
               
                 2150 
                 2157 
                 2151 
                 INVSVEDS 
               
               
                 2388 
                 2394 
                 2393 
                 YDVILMD 
               
               
                 2033 
                 2042 
                 2038 
                 REYVEAIQSS 
               
               
                 643 
                 649 
                 645 
                 ISKLLDS 
               
               
                 2188 
                 2197 
                 2194 
                 GLGLAISKKL 
               
               
                 1627 
                 1633 
                 1628 
                 ERILARQ 
               
               
                 2259 
                 2266 
                 2262 
                 FGSTVKVT 
               
               
                 697 
                 703 
                 700 
                 LQNVTEV 
               
               
                 2067 
                 2086 
                 2074 
                 ENAPFSLNDCIETAIQVSGE 
               
               
                 157 
                 163 
                 162 
                 SETCDSF 
               
               
                 2449 
                 2457 
                 2451 
                 ITKPILPDE 
               
               
                 2167 
                 2178 
                 2172 
                 NKVFGAFSQVDG 
               
               
                 2273 
                 2285 
                 2275 
                 STSVQANDIIFVD 
               
               
                 1731 
                 1737 
                 1734 
                 HLRLAEF 
               
               
                 287 
                 294 
                 292 
                 EWYILSGK 
               
               
                 386 
                 393 
                 390 
                 MFTLHELQ 
               
               
                 2410 
                 2415 
                 2412 
                 KTLFHT 
               
               
                 1378 
                 1392 
                 1380 
                 RRFLTAYAMSQIHTQ 
               
               
                 813 
                 818 
                 817 
                 TSIYKH 
               
               
                 196 
                 207 
                 199 
                 SLPPSSSSQIDF 
               
               
                 129 
                 135 
                 132 
                 HKTIASL 
               
               
                 1530 
                 1540 
                 1539 
                 LYDSEMLLAGH 
               
               
                 2459 
                 2468 
                 2463 
                 RRILTKVGET 
               
               
                 1677 
                 1683 
                 1682 
                 EALQTAH 
               
               
                 663 
                 675 
                 663 
                 RQYYLTKENLLHP 
               
               
                 1178 
                 1188 
                 1181 
                 LLNIGGYLQMA 
               
               
                 35 
                 40 
                 38 
                 PDVKAI 
               
               
                 1466 
                 1471 
                 1468 
                 DLIHPG 
               
               
                 1999 
                 2004 
                 2000 
                 ASFLAN 
               
               
                 583 
                 588 
                 588 
                 QKLIRM 
               
               
                   
               
            
           
           
               
               
            
               
                 5. CAP1 
                   
               
               
                 MSTEESQFNVQGYNIITILKRLEAATSRLEDITIFQEEANKNHYGVDSLTEKGTPKSRTVESSEATSDGKSL 
               
               
                   
               
               
                 ESTSFATFSEAPVEKSKLIVEFENFVESYVHPLVETSKKIDSLVGESAQYFYEAFVEQGKFLELVLQSQQPD 
               
               
                   
               
               
                 MTDPALAKALEPMNAKCTKINELKDSNRKSPFFNHLSTFSESNAVFYWIGIPTPVSYITDTKDTVKFWSDRV 
               
               
                   
               
               
                 LKEYKTKDQVHVEWVKQTLSVFDELKNYVKEYHTTGVAWNPKGKPFAEVVSQQTESAAKNSSSASGSAGGAA 
               
               
                   
               
               
                 PPPPPPPPPATFFDDTEKDSENPSPASGGINAVFAELNQGANITSGLKKVDKSEMTHKNPELRKQPPVAPKK 
               
               
                   
               
               
                 PAPPKKPSSLSGGVSSAPVKKPAKKELIDGTKWIIQNFTKADISDLSPITIEVEMHQSVFIGNCSDVTIQLK 
               
               
                   
               
               
                 GKANAVSVSETKNVALVIDSLISGVDVIKSYKFGIQVLGLVPMLSIDKSDEGTIYLSQESIDNDSQVFTSST 
               
               
                   
               
               
                 TALNINAPKENDDYEELAVPEQFVSKVVNGKLVTQIVEHAG* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 PALAKALEPMNAKCTK 
                 148 
                 0.93 
               
               
                 2 
                 KGTPKSRTVESSEATS 
                 52 
                 0.91 
               
               
                 2 
                 VFYWIGIPTPVSYITD 
                 189 
                 0.91 
               
               
                 3 
                 TVESSEATSDGKSLES 
                 59 
                 0.90 
               
               
                 3 
                 DVTIQLKGKANAVSVS 
                 426 
                 0.90 
               
               
                 3 
                 DKSEMTHKNPELRKQP 
                 339 
                 0.90 
               
               
                 4 
                 EGTIYLSQESIDNDSQ 
                 483 
                 0.89 
               
               
                 5 
                 ELRKQPPVAPKKPAPP 
                 349 
                 0.88 
               
               
                 5 
                 HPLVETSKKIDSLVGE 
                 103 
                 0.88 
               
               
                 6 
                 GGAAPPPPPPPPPATF 
                 285 
                 0.86 
               
               
                 6 
                 KEYHTTGVAWNPKGKP 
                 246 
                 0.86 
               
               
                 6 
                 EWVKQTLSVFDELKNY 
                 229 
                 0.86 
               
               
                 7 
                 MLSIDKSDEGTIYLSQ 
                 475 
                 0.85 
               
               
                 7 
                 TIEVEMHQSVFIGNCS 
                 410 
                 0.85 
               
               
                 7 
                 TIFQEEANKNHYGVDS 
                 33 
                 0.85 
               
               
                 8 
                 VDSLTEKGTPKSRTVE 
                 46 
                 0.84 
               
               
                 9 
                 KELIDGTKWIIQNFTK 
                 385 
                 0.83 
               
               
                 9 
                 GESAQYFYEAFVEQGK 
                 117 
                 0.83 
               
               
                 10 
                 SGLKKVDKSEMTHKNP 
                 333 
                 0.82 
               
               
                 10 
                 PATFFDDTEKDSENPS 
                 297 
                 0.82 
               
               
                 11 
                 PEQFVSKVVNGKLVTQ 
                 524 
                 0.81 
               
               
                 11 
                 HQSVFIGNCSDVTIQL 
                 416 
                 0.81 
               
               
                 11 
                 KWIIQNFTKADISDLS 
                 392 
                 0.81 
               
               
                 12 
                 SQVFTSSTTALNINAP 
                 497 
                 0.80 
               
               
                 13 
                 YEELAVPEQFVSKVVN 
                 518 
                 0.79 
               
               
                 13 
                 TEESQFNVQGYNIITI 
                 3 
                 0.79 
               
               
                 13 
                 TSRLEDITIFQEEANK 
                 26 
                 0.79 
               
               
                 13 
                 PVSYITDTKDTVKFWS 
                 198 
                 0.79 
               
               
                 13 
                 SQQPDMTDPALAKALE 
                 140 
                 0.79 
               
               
                 14 
                 GGVSSAPVKKPAKKEL 
                 372 
                 0.78 
               
               
                 14 
                 PVAPKKPAPPKKPSSL 
                 355 
                 0.78 
               
               
                 15 
                 FGIQVLGLVPMLSIDK 
                 465 
                 0.77 
               
               
                 16 
                 ALNINAPKENDDYEEL 
                 506 
                 0.76 
               
               
                 16 
                 LKEYKTKDQVHVEWVK 
                 217 
                 0.76 
               
               
                 17 
                 FAEVVSQQTESAAKNS 
                 262 
                 0.75 
               
               
                 17 
                 GVAWNPKGKPFAEVVS 
                 252 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 97 
                 109 
                 103 
                 FVESYVHPLVETS 
               
               
                 445 
                 479 
                 470 
                 NVALVIDSLISGVDVIKSYKFGIQVLGLVPMLSID 
               
               
                 520 
                 542 
                 529 
                 ELAVPEQFVSKVVNGKLVTQIVE 
               
               
                 133 
                 141 
                 136 
                 FLELVLQSQ 
               
               
                 223 
                 240 
                 228 
                 KDQVHVEWVKQTLSVFDE 
               
               
                 351 
                 382 
                 377 
                 RKQPPVAPKKPAPPKKPSSLSGGVSSAPVKKP 
               
               
                 262 
                 269 
                 264 
                 FAEVVSQQ 
               
               
                 112 
                 131 
                 125 
                 IDSLVGESAQYFYEAFVEQG 
               
               
                 403 
                 432 
                 427 
                 ISDLSPITIEVEMHQSVFIGNCSDVTIQLK 
               
               
                 186 
                 202 
                 199 
                 SNAVFYWIGIPTPVSYI 
               
               
                 435 
                 441 
                 438 
                 ANAVSVS 
               
               
                 148 
                 154 
                 151 
                 PALAKAL 
               
               
                 77 
                 95 
                 91 
                 FATFSEAPVEKSKLIVEFE 
               
               
                 43 
                 49 
                 46 
                 HYGVDSL 
               
               
                 8 
                 22 
                 16 
                 FNVQGYNIITILKRL 
               
               
                 242 
                 248 
                 247 
                 KNYVKEY 
               
               
                 318 
                 324 
                 322 
                 INAVFAE 
               
               
                 485 
                 491 
                 489 
                 TIYLSQE 
               
               
                 286 
                 299 
                 290 
                 GAAPPPPPPPPPAT 
               
               
                 496 
                 502 
                 500 
                 DSQVFTS 
               
               
                 208 
                 219 
                 219 
                 TVKFWSDRVLKE 
               
               
                 176 
                 183 
                 177 
                 FFNHLSTF 
               
               
                   
               
            
           
           
               
               
            
               
                 6. CDC24 
                   
               
               
                 MEHPPAALRTFSTQSTSSLNSVSTVSSSRIVSSGPVNINNFNKPSTPKDHLFYRCESLKRKLQKIPGMEPFL 
               
               
                   
               
               
                 NQAFNQAEQLSEQQALALAQERSNGNGHSNGKRHQSLDGAMNRLSVGSDSSSIQGSLTRMATNASTSSLISG 
               
               
                   
               
               
                 MPNNNTLFTFTAGVLPANISVDPATHLWKLFQQGAPFCVLINHILPDSQIPVVSSDDLRICKKSVYDFLIAV 
               
               
                   
               
               
                 KTQLNFDDENMFTISNVFSDNAQDLIKIIDVINKLLAEYSDASDSGGGDEDVNMDVQITDERSKVFREIIET 
               
               
                   
               
               
                 ERKYVQDLELMCKYRQDLIEAENLSSEQIHLLFPNLNEIIDFQRRFLNGLECNINVPIRYQRIGSVFIHASL 
               
               
                   
               
               
                 GPFNAYEPWTIGQLTAIDLINKEAANLKKSSSLLDPGFELQSYILKPIQRLCKYPLLLKELIKTSPEYSKQD 
               
               
                   
               
               
                 PHGSSSSTSFNELLVAKTAMKELANQVNEAQRRAENIEHLEKLKERVGNWRGFNLDAQGELLFHGQVGVKDA 
               
               
                   
               
               
                 ENEKEYVAYLFEKIVFFFTEIDDNKKSDKQEKKSKFSTRKRSTSSNLSSSTTNLLESINNSRKDNTLPLELK 
               
               
                   
               
               
                 GRVYISEIYNISAPNTPGSTLIISWSGRKESGSFTLRYRSEEARNQWEKCLRDLKTNEMNKQIHKKLRDSDS 
               
               
                   
               
               
                 SFNTDDSAIYDYTGISTSPVNQSTQQQYYDHRGSHSSRHHSSSSTLSMMKNNRVKSGDLSRISSTSTTLDSF 
               
               
                   
               
               
                 SNNLNGSPNTTNPSLTSSDATKTIPTFDVAIKLLYKSTELSEPLIVNAQIEYNDLLQKIISQIITSNLVADD 
               
               
                   
               
               
                 VNISRLRYKDDEGDFVNLNSDDDWGLVLDMLTSEDFYQTSSNEKRSVTVWVS* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 SSSIQGSLTRMATNAS 
                 122 
                 0.96 
               
               
                 2 
                 SGGGDEDVNMDVQITD 
                 261 
                 0.92 
               
               
                 3 
                 RVYISEIYNISAPNTP 
                 578 
                 0.91 
               
               
                 3 
                 KELIKTSPEYSKQDPH 
                 419 
                 0.91 
               
               
                 3 
                 YSDASDSGGGDEDVNM 
                 255 
                 0.91 
               
               
                 4 
                 GLVLDMLTSEDFYQTS 
                 817 
                 0.90 
               
               
                 5 
                 TKTIPTFDVAIKLLYK 
                 741 
                 0.89 
               
               
                 5 
                 QSTQQQYYDHRGSHSS 
                 670 
                 0.89 
               
               
                 6 
                 SSTSTTLDSFSNNLNG 
                 711 
                 0.88 
               
               
                 6 
                 ARNQWEKCLRDLKTNE 
                 619 
                 0.88 
               
               
                 7 
                 IYNISAPNTPGSTLII 
                 584 
                 0.87 
               
               
                 8 
                 SRLRYKDDEGDFVNLN 
                 796 
                 0.86 
               
               
                 8 
                 PSTPKDHLFYRCESLK 
                 44 
                 0.86 
               
               
                 8 
                 PWTIGQLTAIDLINKE 
                 368 
                 0.86 
               
               
                 9 
                 SRIVSSGPVNINNFNK 
                 28 
                 0.85 
               
               
                 10 
                 NTTNPSLTSSDATKTI 
                 729 
                 0.84 
               
               
                 10 
                 HHSSSSTLSMMKNNRV 
                 687 
                 0.84 
               
               
                 11 
                 DFYQTSSNEKRSVTVW 
                 827 
                 0.83 
               
               
                 12 
                 NNLNGSPNTTNPSLTS 
                 722 
                 0.82 
               
               
                 12 
                 SVFIHASLGPFNAYEP 
                 353 
                 0.82 
               
               
                 12 
                 KVFREIIETERKYVQD 
                 280 
                 0.82 
               
               
                 13 
                 QKIISQIITSNLVADD 
                 777 
                 0.81 
               
               
                 13 
                 HKKLRDSDSSFNTDDS 
                 640 
                 0.81 
               
               
                 13 
                 DLRICKKSVYDFLIAV 
                 201 
                 0.81 
               
               
                 13 
                 TSSLISGMPNNNTLFT 
                 138 
                 0.81 
               
               
                 14 
                 QERSNGNGHSNGKRHQ 
                 92 
                 0.80 
               
               
                 14 
                 YTGISTSPVNQSTQQQ 
                 660 
                 0.80 
               
               
                 14 
                 KESGSFTLRYRSEEAR 
                 605 
                 0.80 
               
               
                 14 
                 GELLFHGQVGVKDAEN 
                 491 
                 0.80 
               
               
                 15 
                 KIPGMEPFLNQAFNQA 
                 64 
                 0.79 
               
               
                 15 
                 TLIISWSGRKESGSFT 
                 596 
                 0.79 
               
               
                 15 
                 AQRRAENIEHLEKLKE 
                 462 
                 0.79 
               
               
                 16 
                 VGVKDAENEKEYVAYL 
                 499 
                 0.78 
               
               
                 16 
                 LVAKTAMKELANQVNE 
                 446 
                 0.78 
               
               
                 16 
                 YSKQDPHGSSSSTSFN 
                 428 
                 0.78 
               
               
                 16 
                 LKPIQRLCKYPLLLKE 
                 405 
                 0.78 
               
               
                 16 
                 FELQSYILKPIQRLCK 
                 398 
                 0.78 
               
               
                 16 
                 LKKSSSLLDPGFELQS 
                 387 
                 0.78 
               
               
                 16 
                 NEIIDFQRRFLNGLEC 
                 325 
                 0.78 
               
               
                 16 
                 RKYVQDLELMCKYRQD 
                 290 
                 0.78 
               
               
                 16 
                 SLTRMATNASTSSLIS 
                 128 
                 0.78 
               
               
                 17 
                 RKRSTSSNLSSSTTNL 
                 543 
                 0.77 
               
               
                 17 
                 KLKERVGNWRGFNLDA 
                 474 
                 0.77 
               
               
                 17 
                 MPNNNTLFTFTAGVLP 
                 145 
                 0.77 
               
               
                 18 
                 NEKEYVAYLFEKIVFF 
                 506 
                 0.76 
               
               
                 18 
                 CKYRQDLIEAENLSSE 
                 300 
                 0.76 
               
               
                 19 
                 NNRVKSGDLSRISSTS 
                 699 
                 0.75 
               
               
                 19 
                 TNLLESINNSRKDNTL 
                 556 
                 0.75 
               
               
                 19 
                 FTEIDDNKKSDKQEKK 
                 522 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 153 
                 219 
                 182 
                 TFTAGVLPANISVDPATHLWKLFQQGAPFCVLINHILPDSQI 
               
               
                   
                   
                   
                 PVVSSDDLRICKKSVYDFLIAVKTQ 
               
               
                 390 
                 425 
                 414 
                 SSSLLDPGFELQSYILKPIQRLCKYPLLLKELIKTS 
               
               
                 746 
                 758 
                 752 
                 TFDVAIKLLYKST 
               
               
                 351 
                 363 
                 357 
                 IGSVFIHASLGPF 
               
               
                 490 
                 502 
                 496 
                 QGELLFHGQVGVK 
               
               
                 761 
                 769 
                 763 
                 SEPLIVNAQ 
               
               
                 509 
                 523 
                 512 
                 EYVAYLFEKIVFFFT 
               
               
                 314 
                 323 
                 319 
                 SEQIHLLFPN 
               
               
                 240 
                 256 
                 244 
                 DLIKIIDVINKLLAEYS 
               
               
                 19 
                 36 
                 33 
                 LNSVSTVSSSRIVSSGPV 
               
               
                 572 
                 588 
                 582 
                 PLELKGRVYISEIYNIS 
               
               
                 443 
                 450 
                 448 
                 NELLVAKT 
               
               
                 291 
                 307 
                 295 
                 KYVQDLELMCKYRQDLI 
               
               
                 772 
                 793 
                 778 
                 YNDLLQKIISQIITSNLVADDV 
               
               
                 48 
                 65 
                 52 
                 KDHLFYRCESLKRKLQKI 
               
               
                 817 
                 822 
                 821 
                 GLVLDM 
               
               
                 81 
                 92 
                 88 
                 QLSEQQALALAQ 
               
               
                 337 
                 349 
                 343 
                 GLECNINVPIRYQ 
               
               
                 371 
                 379 
                 377 
                 IGQLTAIDL 
               
               
                 624 
                 629 
                 628 
                 EKCLRD 
               
               
                 4 
                 11 
                 6 
                 PPAALRTF 
               
               
                 279 
                 284 
                 283 
                 SKVFRE 
               
               
                 595 
                 600 
                 596 
                 STLIIS 
               
               
                 138 
                 143 
                 139 
                 TSSLIS 
               
               
                 665 
                 671 
                 665 
                 TSPVNQS 
               
               
                 673 
                 679 
                 676 
                 QQQYYDH 
               
               
                 685 
                 693 
                 691 
                 SRHHSSSST 
               
               
                   
               
            
           
           
               
               
            
               
                 7. NOT5 
                   
               
               
                 MSARKLQQEFDKLNKKISEGLQAFDEIKDKINATESASQREKLENDLKKELKKLQRSRDQLKQWLGDSSIKL 
               
               
                   
               
               
                 DKNVLQENRTKIEHAMDQFKELEKSSKIKQFSNEGLELQSQQKRSRFGDDAKYQEACTYINEVIEQLNGQNE 
               
               
                   
               
               
                 ELEQELDSLSGQSKRKGGSSIQSSIDDVKYKIERNNSHISKLEEVLENLDNDKLDPARIDDIKDDLDYYVEN 
               
               
                   
               
               
                 NQDEDYVEYDEFYDQLEVDEEDDVEVQGSLAQMAAETEDERRRDEERKREEKEKEKQQQNPPRTSSSVSSSS 
               
               
                   
               
               
                 SSNQNNIGNNTPPATQIKPSVVTVAAIGDQNNNSASSASSTSTPVKKLKPTLAPAPAPPPITSGTSYSNAIK 
               
               
                   
               
               
                 AAQTASTSSTSNSSIAHTANDNNNTNKGNRSVSPLASTDNHTHAPAAVSTPVKVLPPGLNHDTSMNSTLRSE 
               
               
                   
               
               
                 SSSPLVGHAKVNNNHELQISRSQSPMVSNENKVFSDTISRIVNVAHSRLNDPLPLQSITGLLETSLLNCPDS 
               
               
                   
               
               
                 YDAEKPRQYNPVNVHPSSIDYPQEPMYELNSSHYMKKFDNDTLFFCFYYGDGIDSISKYNAAKELSRRGWVF 
               
               
                   
               
               
                 NTEFSQWFSKDSKNGGKNRSMSVIQREEENGNIIGDNSNGNEELREKIDDNGGIPSNYKYFDYEKTWLTRRR 
               
               
                   
               
               
                 ENYQFATENRQIFQ* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 GGIPSNYKYFDYEKTW 
                 628 
                 0.96 
               
               
                 1 
                 PSSIDYPQEPMYELNS 
                 520 
                 0.96 
               
               
                 1 
                 RSESSSPLVGHAKVNN 
                 430 
                 0.96 
               
               
                 2 
                 ASSASSTSTPVKKLKP 
                 323 
                 0.94 
               
               
                 3 
                 IDDIKDDLDYYVENNQ 
                 203 
                 0.92 
               
               
                 4 
                 QWLGDSSIKLDKNVLQ 
                 63 
                 0.91 
               
               
                 4 
                 CFYYGDGIDSISKYNA 
                 550 
                 0.91 
               
               
                 4 
                 TSLLNCPDSYDAEKPR 
                 496 
                 0.91 
               
               
                 4 
                 SSTSNSSIAHTANDNN 
                 368 
                 0.91 
               
               
                 4 
                 GSSIQSSIDDVKYKIE 
                 162 
                 0.91 
               
               
                 5 
                 SLAQMAAETEDERRRD 
                 245 
                 0.90 
               
               
                 6 
                 THAPAAVSTPVKVLPP 
                 402 
                 0.88 
               
               
                 6 
                 CTYINEVIEQLNGQNE 
                 129 
                 0.88 
               
               
                 7 
                 ASTDNHTHAPAAVSTP 
                 396 
                 0.86 
               
               
                 7 
                 VSSSSSSNQNNIGNNT 
                 284 
                 0.86 
               
               
                 7 
                 YDEFYDQLEVDEEDDV 
                 225 
                 0.86 
               
               
                 8 
                 PMYELNSSHYMKKFDN 
                 529 
                 0.85 
               
               
                 8 
                 LQISRSQSPMVSNENK 
                 449 
                 0.85 
               
               
                 8 
                 PVKKLKPTLAPAPAPP 
                 332 
                 0.85 
               
               
                 9 
                 ERKREEKEKEKQQQNP 
                 262 
                 0.84 
               
               
                 10 
                 HDTSMNSTLRSESSSP 
                 421 
                 0.83 
               
               
                 10 
                 SNAIKAAQTASTSSTS 
                 356 
                 0.83 
               
               
                 10 
                 DVEVQGSLAQMAAETE 
                 239 
                 0.83 
               
               
                 10 
                 LELQSQQKRSRFGDDA 
                 108 
                 0.83 
               
               
                 11 
                 PSVVTVAAIGDQNNNS 
                 307 
                 0.82 
               
               
                 11 
                 MSARKLQQEFDKLNKK 
                 1 
                 0.82 
               
               
                 12 
                 NGNIIGDNSNGNEELR 
                 606 
                 0.81 
               
               
                 12 
                 FSQWFSKDSKNGGKNR 
                 580 
                 0.81 
               
               
                 12 
                 SYDAEKPRQYNPVNVH 
                 504 
                 0.81 
               
               
                 12 
                 AETEDERRRDEERKRE 
                 251 
                 0.81 
               
               
                 12 
                 DAKYQEACTYINEVIE 
                 122 
                 0.81 
               
               
                 13 
                 LEEVLENLDNDKLDPA 
                 186 
                 0.80 
               
               
                 13 
                 SEGLQAFDEIKDKINA 
                 18 
                 0.80 
               
               
                 14 
                 DYEKTWLTRRRENYQF 
                 638 
                 0.79 
               
               
                 14 
                 NPVNVHPSSIDYPQEP 
                 514 
                 0.79 
               
               
                 14 
                 DEDYVEYDEFYDQLEV 
                 219 
                 0.79 
               
               
                 15 
                 KELSRRGWVFNTEFSQ 
                 567 
                 0.78 
               
               
                 16 
                 NEELREKIDDNGGIPS 
                 617 
                 0.77 
               
               
                 16 
                 MSVIQREEENGNIIGD 
                 597 
                 0.77 
               
               
                 16 
                 DTISRIVNVAHSRLND 
                 468 
                 0.77 
               
               
                 16 
                 SASQREKLENDLKKEL 
                 36 
                 0.77 
               
               
                 16 
                 APPPITSGTSYSNAIK 
                 345 
                 0.77 
               
               
                 17 
                 TNKGNRSVSPLASTDN 
                 385 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 302 
                 315 
                 312 
                 ATQIKPSVVTVAAI 
               
               
                 547 
                 554 
                 550 
                 LFFCFYYG 
               
               
                 403 
                 419 
                 414 
                 HAPAAVSTPVKVLPPGL 
               
               
                 434 
                 441 
                 440 
                 SSPLVGHA 
               
               
                 470 
                 479 
                 476 
                 ISRIVNVAHS 
               
               
                 482 
                 504 
                 487 
                 NDPLPLQSITGLLETSLLNCPDS 
               
               
                 391 
                 396 
                 394 
                 SVSPLA 
               
               
                 513 
                 526 
                 518 
                 YNPVNVHPSSIDYP 
               
               
                 239 
                 249 
                 243 
                 DVEVQGSLAQM 
               
               
                 126 
                 138 
                 132 
                 QEACTYINEVIEQ 
               
               
                 329 
                 350 
                 343 
                 TSTPVKKLKPTLAPAPAPPPIT 
               
               
                 228 
                 234 
                 231 
                 FYDQLEV 
               
               
                 209 
                 215 
                 211 
                 DLDYYVE 
               
               
                 183 
                 192 
                 187 
                 ISKLEEVLEN 
               
               
                 281 
                 287 
                 285 
                 SSSVSSS 
               
               
                 165 
                 175 
                 171 
                 IQSSIDDVKYK 
               
               
                 221 
                 226 
                 225 
                 DYVEYD 
               
               
                 449 
                 454 
                 452 
                 LQISRS 
               
               
                 18 
                 25 
                 24 
                 SEGLQAFD 
               
               
                 149 
                 156 
                 153 
                 ELDSLSGQ 
               
               
                 597 
                 602 
                 598 
                 MSVIQR 
               
               
                 49 
                 54 
                 54 
                 KELKKL 
               
               
                 632 
                 639 
                 633 
                 SNYKYFDY 
               
               
                 356 
                 365 
                 361 
                 SNAIKAAQTA 
               
               
                 4 
                 10 
                 5 
                 RKLQQEF 
               
               
                   
               
            
           
           
               
               
            
               
                 8. IPF11281(GPR1) 
                   
               
               
                 MPDLISIATSPTKAFTPAATPTTIPTTIATIAASVSAATATVTTIIKDSTDDSTTTASILSALFNDIILPTI 
               
               
                   
               
               
                 FKRDYSTRDHKANQLGQFTDHQARVQRIVAISSSCGSIAAVLIAMYFLFAIDPKRIVFRHQLIFFLLFFDLL 
               
               
                   
               
               
                 KACILLLYPTRILTHSSAYYNHNFCQVVGFFTATAIEGADIAIFAFAFHTYLLIFKPSFNTKVKNSNRVEGG 
               
               
                   
               
               
                 LYKFRYYVYSLSFFVPLIVASLAFIHSDGYDSLVCWCYLPMRPVWLRLVLSWVPRYCIVVGIFVIYGLIYIR 
               
               
                   
               
               
                 VISEFKTLGGVFKNAAGNGGAGNLHLASNSNPTFFSSLKYFFVSMKDQWFPNMSDDTIAPITSRHSHSHNAS 
               
               
                   
               
               
                 GTIASPHRNVIGEIDNDDGDDDSEELAEALEDESVDYQDIELNKQSSRNSYRHHNSDIQQANLENFRRRQRI 
               
               
                   
               
               
                 IQKQMKSIFIYPFAYCLVWLFPFILQATQFNYEEDHHAVYWLNVLGALSQPLNGFVDTLVFFYRERPWRNTA 
               
               
                   
               
               
                 MKNFEKENRQRVDNIIVNNLEQRKYSEGAESAQTVATASKRIAKNSLSASSGLVNINAYKPWRQFMNKYRFP 
               
               
                   
               
               
                 FYQLPTDKNIAKFQDRYIRRKLRDSRKLDKLVQEVTRDRQDLTFPTNIAEKYGDGSGNGSGSGSGGHHGGST 
               
               
                   
               
               
                 ISNTNDSSPMSMGAGINWTEPTNAHDFSNILNTGGNSNVSSWGTKDVPGFKPNFGKFTFGNRSSNLLSRKSS 
               
               
                   
               
               
                 TVIGLHGTGRNVRQPSNDSFNDPVRSLGGRRNSSLVIGNNTTLNKPYEIVSSPTSSTFTPIDRVKSNEDIDE 
               
               
                   
               
               
                 LHTVDNDTDKADDNDDGELDLMEFLKKGPPM* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 STVIGLHGTGRNVRQP 
                 720 
                 0.95 
               
               
                 2 
                 YLLIFKPSFNTKVKNS 
                 195 
                 0.93 
               
               
                 3 
                 VSSWGTKDVPGFKPNF 
                 687 
                 0.92 
               
               
                 3 
                 VTTIIKDSTDDSTTTA 
                 42 
                 0.92 
               
               
                 4 
                 TFTPIDRVKSNEDIDE 
                 777 
                 0.91 
               
               
                 4 
                 NGSGSGSGGHHGGSTI 
                 634 
                 0.91 
               
               
                 4 
                 SRHSHSHNASGTIASP 
                 351 
                 0.91 
               
               
                 5 
                 NEDIDELHTVDNDTDK 
                 787 
                 0.90 
               
               
                 5 
                 TIFKRDYSTRDHKANQ 
                 71 
                 0.90 
               
               
                 6 
                 TGRNVRQPSNDSFNDP 
                 728 
                 0.88 
               
               
                 7 
                 GHHGGSTISNTNDSSP 
                 642 
                 0.87 
               
               
                 7 
                 HHAVYWLNVLGALSQP 
                 468 
                 0.87 
               
               
                 8 
                 DRYIRRKLRDSRKLDK 
                 591 
                 0.86 
               
               
                 8 
                 TIAPITSRHSHSHNAS 
                 345 
                 0.86 
               
               
                 9 
                 GAGINWTEPTNAHDFS 
                 661 
                 0.85 
               
               
                 9 
                 FFVSMKDQWFPNMSDD 
                 329 
                 0.85 
               
               
                 9 
                 GGAGNLHLASNSNPTF 
                 307 
                 0.85 
               
               
                 10 
                 TVDNDTDKADDNDDGE 
                 795 
                 0.84 
               
               
                 10 
                 GGRRNSSLVIGNNTTL 
                 748 
                 0.84 
               
               
                 10 
                 LNTGGNSNVSSWGTKD 
                 679 
                 0.84 
               
               
                 10 
                 SDIQQANLENFRRRQR 
                 416 
                 0.84 
               
               
                 10 
                 NDDGDDDSEELAEALE 
                 376 
                 0.84 
               
               
                 11 
                 TASILSALFNDIILPT 
                 56 
                 0.83 
               
               
                 11 
                 TIATIAASVSAATATV 
                 27 
                 0.83 
               
               
                 11 
                 SLAFIHSDGYDSLVCW 
                 237 
                 0.83 
               
               
                 12 
                 NTNDSSPMSMGAGINW 
                 651 
                 0.82 
               
               
                 12 
                 HRNVIGEIDNDDGDDD 
                 367 
                 0.82 
               
               
                 12 
                 DSLVCWCYLPMRPVWL 
                 247 
                 0.82 
               
               
                 12 
                 PDLISIATSPTKAFTP 
                 2 
                 0.82 
               
               
                 13 
                 QSSRNSYRHHNSDIQQ 
                 405 
                 0.81 
               
               
                 13 
                 CYLPMRPVWLRLVLSW 
                 253 
                 0.81 
               
               
                 13 
                 PTRILTHSSAYYNHNF 
                 153 
                 0.81 
               
               
                 14 
                 FFYRERPWRNTAMKNF 
                 493 
                 0.80 
               
               
                 14 
                 SGTIASPHRNVIGEID 
                 360 
                 0.80 
               
               
                 14 
                 YGLIYIRVISEFKTLG 
                 282 
                 0.80 
               
               
                 14 
                 NRVEGGLYKFRYYVYS 
                 211 
                 0.80 
               
               
                 14 
                 IVAISSSCGSIAAVLI 
                 100 
                 0.80 
               
               
                 15 
                 PYEIVSSPTSSTFTPI 
                 766 
                 0.79 
               
               
                 15 
                 NIAEKYGDGSGNGSGS 
                 623 
                 0.79 
               
               
                 15 
                 NFEKENRQRVDNIIVN 
                 507 
                 0.79 
               
               
                 15 
                 MKSIFIYPFAYCLVWL 
                 437 
                 0.79 
               
               
                 15 
                 GVFKNAAGNGGAGNLH 
                 298 
                 0.79 
               
               
                 16 
                 ATSPTKAFTPAATPTT 
                 8 
                 0.78 
               
               
                 16 
                 LVNINAYKPWRQFMNK 
                 557 
                 0.78 
               
               
                 17 
                 FKPNFGKFTFGNRSSN 
                 698 
                 0.77 
               
               
                 17 
                 NLEQRKYSEGAESAQT 
                 523 
                 0.77 
               
               
                 17 
                 PWRNTAMKNFEKENRQ 
                 499 
                 0.77 
               
               
                 17 
                 VPLIVASLAFIHSDGY 
                 231 
                 0.77 
               
               
                 17 
                 HQLIFFLLFFDLLKAC 
                 132 
                 0.77 
               
               
                 18 
                 SLSASSGLVNINAYKP 
                 550 
                 0.76 
               
               
                 18 
                 ALEDESVDYQDIELNK 
                 389 
                 0.76 
               
               
                 18 
                 QVVGFFTATAIEGADI 
                 170 
                 0.76 
               
               
                 19 
                 TRDRQDLTFPTNIAEK 
                 612 
                 0.75 
               
               
                 19 
                 LQATQFNYEEDHHAVY 
                 457 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 246 
                 293 
                 252 
                 YDSLVCWCYLPMRPVWLRLVLSWVPRYCIVVGIFVIY 
               
               
                   
                   
                   
                 GLIYIRVISEF 
               
               
                 94 
                 178 
                 150 
                 QARVQRIVAISSSCGSIAAVLIAMYFLFAIDPKRIVF 
               
               
                   
                   
                   
                 RHQLIFFLLFFDLLKACILLLYPTRILTHSSAYYNHN 
               
               
                   
                   
                   
                 FCQVVGFFTAT 
               
               
                 439 
                 461 
                 450 
                 SIFIYPFAYCLVWLFPFILQATQ 
               
               
                 215 
                 244 
                 232 
                 GGLYKFRYYVYSLSFFVPLIVASLAFIHSD 
               
               
                 467 
                 496 
                 474 
                 DHHAVYWLNVLGALSQPLNGFVDTLVFFYR 
               
               
                 323 
                 333 
                 328 
                 FSSLKYFFVSM 
               
               
                 182 
                 201 
                 195 
                 GADIAIFAFAFHTYLLIFKP 
               
               
                 57 
                 72 
                 61 
                 ASILSALFNDIILPTI 
               
               
                 25 
                 45 
                 34 
                 PTTIATIAASVSAATATVTTI 
               
               
                 575 
                 581 
                 578 
                 FPFYQLP 
               
               
                 604 
                 611 
                 609 
                 LDKLVQEV 
               
               
                 719 
                 726 
                 723 
                 SSTVIGLH 
               
               
                 766 
                 773 
                 770 
                 PYEIVSSP 
               
               
                 548 
                 561 
                 555 
                 KNSLSASSGLVNIN 
               
               
                 4 
                 10 
                 5 
                 LISIATS 
               
               
                 753 
                 758 
                 755 
                 SSLVIG 
               
               
                 395 
                 400 
                 397 
                 VDYQDI 
               
               
                 536 
                 545 
                 539 
                 AQTVATASKR 
               
               
                 362 
                 373 
                 368 
                 TIASPHRNVIGE 
               
               
                 741 
                 747 
                 746 
                 NDPVRSL 
               
               
                 346 
                 354 
                 348 
                 IAPITSRHS 
               
               
                   
               
            
           
           
               
               
            
               
                 9. PPR1 
                   
               
               
                 MSESPSQPPQKKHKPTTTGPSSSSSSKLTRAISACKRCRTKKIKCDQKFPQCGKCEVNGVECIGVDSVTGRE 
               
               
                   
               
               
                 IPRSYIVHLEERVKFLEEKLRLQDRSGFVDEGVSSTPPGSSTIKKKSNEISINEPLIKKESPLINTKLDSIA 
               
               
                   
               
               
                 FSKIMSTAVRVQNRLSDPNIKPGNGNVNLGHNSTTTNENGIDINNDISRAVLPPKSTAMQFLRVFFHQCNSQ 
               
               
                   
               
               
                 LPLFHREEFLRDYFIPIYGEFDESISLASNNTKINKSFFNSSSSDGDKTPCWFDVYKSKIQQLLTENTQNDI 
               
               
                   
               
               
                 QTIANNIIPPLKYRKPLYFLNLVFAVATSANHLRYPIHISESFRLAAMRFSQDVDNSIDPLEHLQGILLYAG 
               
               
                   
               
               
                 YSIMRPTNPGVWYIMGEALRICVDLDLQNELKTKSKQNFNIDNFTRDKRRRIFWCCYSIDRQICFYLDRPFG 
               
               
                   
               
               
                 IPDESINTPYPSSLDDSKIIPNDNSTDYYYYKNHHHHHHHDDDNDDNEDDINFSYKNVSLLFFKIRKIQSQV 
               
               
                   
               
               
                 TKILYTNAEIPREYKDLNHWKQSILIQLTQWKQELQSKLISKQLNCDFNEIFFQLNYHHTLLYIHGLSPKNY 
               
               
                   
               
               
                 KLSLIDYENLTNSSIQVINCYTELLKTKSINYTWAGVHNLFMAGTSYLYALYNSKEIRLINSIDQVQKITND 
               
               
                   
               
               
                 CLLVLQSLIGRCDAANYCCEIFHNLTMIIINLKYAPKDKKHLTELKPANSIPSSSFSSSSSFSSSSSTSSSK 
               
               
                   
               
               
                 ISRESLYRINNGNVHSNLFHLVTELDHLNPLTKTKTINNNNSDHFDITNDEKQDHDSTIITDDLSSPPIDSS 
               
               
                   
               
               
                 LLPLNQQTILQWNDEELQNFLNELNQSNQSNQSSPNNNSSIRDEKKTFELIHDMPNEIIWDEFFANKQ* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 ANNIIPPLKYRKPLYF 
                 292 
                 0.92 
               
               
                 2 
                 DSTIITDDLSSPPIDS 
                 776 
                 0.91 
               
               
                 2 
                 SDGDKTPCWFDVYKSK 
                 260 
                 0.91 
               
               
                 3 
                 SPPIDSSLLPLNQQTI 
                 786 
                 0.90 
               
               
                 3 
                 CCEIFHNLTMIIINLK 
                 666 
                 0.90 
               
               
                 3 
                 DESISLASNNTKINKS 
                 238 
                 0.90 
               
               
                 4 
                 DESINTPYPSSLDDSK 
                 435 
                 0.89 
               
               
                 5 
                 HFDITNDEKQDHDSTI 
                 764 
                 0.88 
               
               
                 5 
                 TKSINYTWAGVHNLFM 
                 603 
                 0.88 
               
               
                 5 
                 KSKIQQLLTENTQNDI 
                 273 
                 0.88 
               
               
                 6 
                 SSIRDEKKTFELIHDM 
                 831 
                 0.86 
               
               
                 6 
                 QSLIGRCDAANYCCEI 
                 654 
                 0.86 
               
               
                 6 
                 GILLYAGYSIMRPTNP 
                 354 
                 0.86 
               
               
                 6 
                 SSTPPGSSTIKKKSNE 
                 106 
                 0.86 
               
               
                 7 
                 TKTINNNNSDHFDITN 
                 754 
                 0.85 
               
               
                 7 
                 TDYYYYKNHHHHHHHD 
                 458 
                 0.85 
               
               
                 8 
                 YPSSLDDSKIIPNDNS 
                 442 
                 0.84 
               
               
                 8 
                 CYSIDRQICFYLDRPF 
                 416 
                 0.84 
               
               
                 8 
                 NKSFFNSSSSDGDKTP 
                 251 
                 0.84 
               
               
                 8 
                 SSSSSSKLTRAISACK 
                 21 
                 0.84 
               
               
                 8 
                 SPLINTKLDSIAFSKI 
                 133 
                 0.84 
               
               
                 9 
                 NSSIQVINCYTELLKT 
                 588 
                 0.83 
               
               
                 9 
                 HHHDDDNDDNEDDINF 
                 470 
                 0.83 
               
               
                 9 
                 GVWYIMGEALRICVDL 
                 370 
                 0.83 
               
               
                 9 
                 AISACKRCRTKKIKCD 
                 31 
                 0.83 
               
               
                 9 
                 DYFIPIYGEFDESISL 
                 228 
                 0.83 
               
               
                 9 
                 GHNSTTTNENGIDINN 
                 174 
                 0.83 
               
               
                 10 
                 AEIPREYKDLNHWKQS 
                 512 
                 0.82 
               
               
                 10 
                 PLKYRKPLYFLNLVFA 
                 298 
                 0.82 
               
               
                 10 
                 NGIDINNDISRAVLPP 
                 183 
                 0.82 
               
               
                 10 
                 NRLSDPNIKPGNGNVN 
                 157 
                 0.82 
               
               
                 10 
                 FSKIMSTAVRVQNRLS 
                 145 
                 0.82 
               
               
                 11 
                 IRKIQSQVTKILYTNA 
                 497 
                 0.81 
               
               
                 12 
                 IRLINSIDQVQKITND 
                 633 
                 0.80 
               
               
                 12 
                 YLDRPFGIPDESINTP 
                 426 
                 0.80 
               
               
                 13 
                 LRLQDRSGFVDEGVSS 
                 92 
                 0.79 
               
               
                 13 
                 AGTSYLYALYNSKEIR 
                 619 
                 0.79 
               
               
                 13 
                 QLNYHHTLLYIHGLSP 
                 558 
                 0.79 
               
               
                 13 
                 GYSIMRPTNPGVWYIM 
                 360 
                 0.79 
               
               
                 13 
                 ESPSQPPQKKHKPTTT 
                 3 
                 0.79 
               
               
                 13 
                 SSTIKKKSNEISINEP 
                 112 
                 0.79 
               
               
                 14 
                 PLIKKESPLINTKLDS 
                 127 
                 0.78 
               
               
                 15 
                 HREEFLRDYFIPIYGE 
                 221 
                 0.77 
               
               
                 15 
                 HKPTTTGPSSSSSSKL 
                 13 
                 0.77 
               
               
                 16 
                 HDMPNEIIWDEFFANK 
                 844 
                 0.76 
               
               
                 16 
                 LTMIIINLKYAPKDKK 
                 673 
                 0.76 
               
               
                 17 
                 REIPRSYIVHLEERVK 
                 71 
                 0.75 
               
               
                 17 
                 SILIQLTQWKQELQSK 
                 527 
                 0.75 
               
               
                 17 
                 KFPQCGKCEVNGVECI 
                 48 
                 0.75 
               
               
                 17 
                 ESFRLAAMRFSQDVDN 
                 329 
                 0.75 
               
               
                 17 
                 KSTAMQFLRVFFHQCN 
                 199 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 635 
                 660 
                 652 
                 LINSIDQVQKITNDCLLVLQSLIGRC 
               
               
                 294 
                 318 
                 311 
                 NIIPPLKYRKPLYFLNLVFAVATSA 
               
               
                 379 
                 386 
                 382 
                 LRICVDLD 
               
               
                 662 
                 683 
                 668 
                 AANYCCEIFHNLTMIIINLKYA 
               
               
                 412 
                 430 
                 415 
                 IFWCCYSIDRQICFYLDRP 
               
               
                 40 
                 68 
                 65 
                 TKKIKCDQKFPQCGKCEVNGVECIGVDSV 
               
               
                 621 
                 630 
                 625 
                 TSYLYALYNS 
               
               
                 589 
                 603 
                 594 
                 SSIQVINCYTELLKT 
               
               
                 555 
                 583 
                 568 
                 IFFQLNYHHTLLYIHGLSPKNYKLSLIDY 
               
               
                 487 
                 511 
                 493 
                 YKNVSLLFFKIRKIQSQVTKILYTN 
               
               
                 203 
                 223 
                 210 
                 MQFLRVFFHQCNSQLPLFHRE 
               
               
                 348 
                 361 
                 355 
                 PLEHLQGILLYAGY 
               
               
                 75 
                 95 
                 78 
                 RSYIVHLEERVKFLEEKLRLQ 
               
               
                 266 
                 280 
                 269 
                 PCWFDVYKSKIQQLL 
               
               
                 735 
                 751 
                 739 
                 HSNLFHLVTELDHLNPL 
               
               
                 28 
                 38 
                 35 
                 LTRAISACKRC 
               
               
                 526 
                 534 
                 529 
                 QSILIQLTQ 
               
               
                 192 
                 199 
                 194 
                 SRAVLPPK 
               
               
                 320 
                 336 
                 324 
                 HLRYPIHISESFRLAAM 
               
               
                 459 
                 472 
                 469 
                 DYYYYKNHHHHHHH 
               
               
                 785 
                 802 
                 793 
                 SSPPIDSSLLPLNQQTIL 
               
               
                 227 
                 235 
                 232 
                 RDYFIPIYG 
               
               
                 150 
                 158 
                 153 
                 STAVRVQNR 
               
               
                 539 
                 551 
                 542 
                 LQSKLISKQLNCD 
               
               
                 610 
                 616 
                 614 
                 WAGVHNL 
               
               
                 141 
                 147 
                 143 
                 DSIAFSK 
               
               
                 696 
                 713 
                 701 
                 ANSIPSSSFSSSSSFSSS 
               
               
                 129 
                 138 
                 137 
                 IKKESPLINT 
               
               
                 723 
                 728 
                 724 
                 RESLYR 
               
               
                 840 
                 845 
                 841 
                 FELIHD 
               
               
                 5 
                 12 
                 7 
                 PSQPPQKK 
               
               
                   
               
            
           
           
               
               
            
               
                 10. IPF3598(SIP3) 
                   
               
               
                 MVKSPKSDKSKPLPSQPHQETLLHHFKLISVNFKEAALDSPSFRASMNHLDLQINTIEQWLTALASSFKKIP 
               
               
                   
               
               
                 KYLKEVQSYSNSFLEHLVPTFIQDGIIDQEYTVTGLNTTLDGLKTVWGLSIQALSVDAKNLKSIELFKRHHV 
               
               
                   
               
               
                 IKYKETRKRYEDYQAKYDKYLSIYLSSSKSKDPLMVIEDAKQLYQVRKEYIHASLDLVIEIQNLSKNLNKLL 
               
               
                   
               
               
                 VGVNTDLWRNKWNIFGSRGVGDAIKEEWDKIQRIQSWNDSYTLAIEKLNSDMLAARNQVEEGCHIQFQPSTN 
               
               
                   
               
               
                 VNDYKSTIINNRTLRDIDEPGVEKHGYLFMKTWTEKSSKPIWVHRWAFIKNGVFGLLVVSPSQTFVQETDKI 
               
               
                   
               
               
                 GILLCNVRYAPNEDRRFCFEIRTNDFTAVFQAESLVELKSWLKVFENEKFRISGPEAISNGLFNIASGRFPP 
               
               
                   
               
               
                 IISEFSSTVDTVIDQQLTNAKVTLAGGQIVAASSLSNHLERFEDFFKKYMYFEIPKICPPFMTDTTKSSIMA 
               
               
                   
               
               
                 YCLTSPTQIPNALTANIWGSVNWGLYYLHDTARDSSTYLTGKDAEMIKFQEEHFENDKFYPDFYPKEYVNLD 
               
               
                   
               
               
                 IQMRALFETAVEPGEYCVLSYSCIWSPNSKQELSGRCFVTNYHMYFYMQALGFVALFKGFLGHLVSVEFVSQ 
               
               
                   
               
               
                 KNYDLMKVYNIDGVIKMKVFLDDAICIKKKLVYLINNIVSDKPKSLEGVLADFSDIEKEIAVEKSDQKNLRE 
               
               
                   
               
               
                 ISQLSKGLSSKSLASEKLLLSGETSSILPGKSGRMIKHRVNFTPDYNLISDRTYPAPPKAIFHALLGDNSVV 
               
               
                   
               
               
                 FRSQLSFASTKYFLQKPWATSSKGTLYRDFNVPAMYDGKDCFVQVRQEIDNMEDNTYYTFTHEMSKFELLLG 
               
               
                   
               
               
                 SPYKTVFKIVIVEHISKRSKVFVYSKTYFDRLSVWNPLVIRLNNQVDVNKVRKLEKSISEAVKEIGTHGMIV 
               
               
                   
               
               
                 RAIYLYGKLSHTSKPEAVTSTSVIKFGIVSLFKLGLGKAFSKAYSFAVKSFIKPFQLVVLLLKSLRMNVFLV 
               
               
                   
               
               
                 FIIVLLSFLNLFLAGKTATSYWNTRSASKLAQEYVTKEPRMLQRSVYLKDLESILNENISIAESRPFSLFKQ 
               
               
                   
               
               
                 NSFIFNLDADSDWSNYFGSNARDVARSLKSSFQDIGIKRHELLVKLKILKSMEEEIIQAEWQNWLMSEAQKC 
               
               
                   
               
               
                 DYVMDNVVGQIDEVDNYQEGVDNIIEYCHECKKILANLV* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 PGVEKHGYLFMKTWTE 
                 308 
                 0.93 
               
               
                 2 
                 AEMIKFQEEHFENDKF 
                 548 
                 0.92 
               
               
                 2 
                 KSSIMAYCLTSPTQIP 
                 499 
                 0.92 
               
               
                 3 
                 PAMYDGKDCFVQVRQE 
                 825 
                 0.91 
               
               
                 3 
                 KEAALDSPSFRASMNH 
                 34 
                 0.91 
               
               
                 4 
                 SEAQKCDYVMDNVVGQ 
                 1147 
                 0.90 
               
               
                 5 
                 QDGIIDQEYTVTGLNT 
                 95 
                 0.89 
               
               
                 5 
                 PKAIFHALLGDNSVVF 
                 778 
                 0.89 
               
               
                 5 
                 AVEPGEYCVLSYSCIW 
                 586 
                 0.89 
               
               
                 6 
                 ATSSKGTLYRDFNVPA 
                 811 
                 0.88 
               
               
                 6 
                 ALLGDNSVVFRSQLSF 
                 784 
                 0.88 
               
               
                 6 
                 KEVQSYSNSFLEHLVP 
                 76 
                 0.88 
               
               
                 6 
                 GRMIKHRVNFTPDYNL 
                 753 
                 0.88 
               
               
                 6 
                 HDTARDSSTYLTGKDA 
                 533 
                 0.88 
               
               
                 6 
                 KSTIINNRTLRDIDEP 
                 293 
                 0.88 
               
               
                 7 
                 DGVIKMKVFLDDAICI 
                 660 
                 0.87 
               
               
                 7 
                 KFRISGPEAISNGLFN 
                 409 
                 0.87 
               
               
                 8 
                 CNVRYAPNEDRRFCFE 
                 365 
                 0.86 
               
               
                 8 
                 KETRKRYEDYQAKYDK 
                 148 
                 0.86 
               
               
                 9 
                 GCHIQFQPSTNVNDYK 
                 278 
                 0.85 
               
               
                 10 
                 YGKLSHTSKPEAVTST 
                 942 
                 0.84 
               
               
                 10 
                 NMEDNTYYTFTHEMSK 
                 843 
                 0.84 
               
               
                 10 
                 CVLSYSCIWSPNSKQE 
                 593 
                 0.84 
               
               
                 10 
                 YFEIPKICPPFMTDTT 
                 483 
                 0.84 
               
               
                 10 
                 KPIWVHRWAFIKNGVF 
                 327 
                 0.84 
               
               
                 10 
                 GLSIQALSVDAKNLKS 
                 120 
                 0.84 
               
               
                 10 
                 QEGVDNIIEYCHECKK 
                 1170 
                 0.84 
               
               
                 10 
                 VGQIDEVDNYQEGVDN 
                 1160 
                 0.84 
               
               
                 10 
                 QAEWQNWLMSEAQKCD 
                 1138 
                 0.84 
               
               
                 10 
                 DSDWSNYFGSNARDVA 
                 1090 
                 0.84 
               
               
                 11 
                 DRTYPAPPKAIFHALL 
                 771 
                 0.83 
               
               
                 11 
                 IQRIQSWNDSYTLAIE 
                 247 
                 0.83 
               
               
                 11 
                 IKEEWDKIQRIQSWND 
                 240 
                 0.83 
               
               
                 11 
                 ISIAESRPFSLFKQNS 
                 1067 
                 0.83 
               
               
                 12 
                 QVRQEIDNMEDNTYYT 
                 836 
                 0.82 
               
               
                 12 
                 RALFETAVEPGEYCVL 
                 580 
                 0.82 
               
               
                 12 
                 LLVGVNTDLWRNKWNI 
                 215 
                 0.82 
               
               
                 13 
                 TSVIKFGIVSLFKLGL 
                 957 
                 0.81 
               
               
                 13 
                 FVSQKNYDLMKVYNID 
                 645 
                 0.81 
               
               
                 13 
                 FMTDTTKSSIMAYCLT 
                 493 
                 0.81 
               
               
                 13 
                 SQPHQETLLHHFKLIS 
                 15 
                 0.81 
               
               
                 13 
                 HHVIKYKETRKRYEDY 
                 142 
                 0.81 
               
               
                 14 
                 FVYSKTYFDRLSVWNP 
                 886 
                 0.80 
               
               
                 14 
                 GVLADFSDIEKEIAVE 
                 696 
                 0.80 
               
               
                 14 
                 SVNWGLYYLHDTARDS 
                 524 
                 0.80 
               
               
                 14 
                 LRDIDEPGVEKHGYLF 
                 302 
                 0.80 
               
               
                 14 
                 DLVIEIQNLSKNLNKL 
                 200 
                 0.80 
               
               
                 14 
                 SKLAQEYVTKEPRMLQ 
                 1036 
                 0.80 
               
               
                 15 
                 QEEHFENDKFYPDFYP 
                 554 
                 0.79 
               
               
                 15 
                 TFVQETDKIGILLCNV 
                 352 
                 0.79 
               
               
                 15 
                 TNVNDYKSTIINNRTL 
                 287 
                 0.79 
               
               
                 16 
                 KSDKSKPLPSQPHQET 
                 6 
                 0.78 
               
               
                 16 
                 KFYPDFYPKEYVNLDI 
                 562 
                 0.78 
               
               
                 16 
                 DKYLSIYLSSSKSKDP 
                 162 
                 0.78 
               
               
                 17 
                 VDTVIDQQLTNAKVTL 
                 441 
                 0.76 
               
               
                 18 
                 HGMIVRAIYLYGKLSH 
                 932 
                 0.75 
               
               
                 18 
                 KIVIVEHISKRSKVFV 
                 872 
                 0.75 
               
               
                 18 
                 GLFNIASGRFPPIISE 
                 421 
                 0.75 
               
               
                 18 
                 RRFCFEIRTNDFTAVF 
                 375 
                 0.75 
               
               
                 18 
                 SSFQDIGIKRHELLVK 
                 1110 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 977 
                 1000 
                 995 
                 SKAYSFAVKSFIKPFQLVVLLLKS 
               
               
                 1002 
                 1024 
                 1010 
                 RMNVFLVFIIVLLSFLNLFLAGK 
               
               
                 589 
                 602 
                 596 
                 PGEYCVLSYSCIWS 
               
               
                 338 
                 357 
                 344 
                 KNGVFGLLVVSPSQTFVQET 
               
               
                 859 
                 879 
                 873 
                 FELLLGSPYKTVFKIVIVEHI 
               
               
                 610 
                 650 
                 643 
                 SGRCFVTNYHMYFYMQALGFVALFKGFLGHLVSVEFVSQKN 
               
               
                 831 
                 839 
                 836 
                 KDCFVQVRQ 
               
               
                 1119 
                 1129 
                 1125 
                 RHELLVKLKIL 
               
               
                 360 
                 370 
                 366 
                 IGILLCNVRYA 
               
               
                 951 
                 975 
                 967 
                 PEAVTSTSVIKFGIVSLFKLGLGKA 
               
               
                 664 
                 686 
                 680 
                 KMKVFLDDAICIKKKLVYLINNI 
               
               
                 933 
                 948 
                 939 
                 GMIVRAIYLYGKLSHT 
               
               
                 774 
                 809 
                 794 
                 YPAPPKAIFHALLGDNSVVFRSQLSFASTKYFLQKP 
               
               
                 157 
                 172 
                 167 
                 YQAKYDKYLSIYLSSS 
               
               
                 60 
                 93 
                 88 
                 WLTALASSFKKIPKYLKEVQSYSNSFLEHLVPTF 
               
               
                 19 
                 41 
                 25 
                 QETLLHHFKLISVNFKEAALDSP 
               
               
                 177 
                 206 
                 200 
                 PLMVIEDAKQLYQVRKEYIHASLDLVIEIQ 
               
               
                 881 
                 891 
                 886 
                 KRSKVFVYSKT 
               
               
                 1051 
                 1062 
                 1053 
                 QRSVYLKDLESI 
               
               
                 1174 
                 1188 
                 1180 
                 DNIIEYCHECKKILA 
               
               
                 451 
                 470 
                 464 
                 NAKVTLAGGQIVAASSLSNH 
               
               
                 893 
                 907 
                 901 
                 FDRLSVWNPLVIRLN 
               
               
                 115 
                 131 
                 125 
                 LKTVWGLSIQALSVDAK 
               
               
                 502 
                 511 
                 504 
                 IMAYCLTSPT 
               
               
                 276 
                 284 
                 282 
                 EEGCHIQFQ 
               
               
                 213 
                 220 
                 216 
                 NKLLVGVN 
               
               
                 483 
                 493 
                 489 
                 YFEIPKICPPF 
               
               
                 1149 
                 1164 
                 1152 
                 AQKCDYVMDNVVGQID 
               
               
                 135 
                 147 
                 145 
                 SIELFKRHHVIKY 
               
               
                 526 
                 534 
                 532 
                 NWGLYYLHD 
               
               
                 387 
                 405 
                 397 
                 TAVFQAESLVELKSWLKVF 
               
               
                 694 
                 701 
                 696 
                 LEGVLADF 
               
               
                 1035 
                 1045 
                 1040 
                 ASKLAQEYVTK 
               
               
                 564 
                 576 
                 570 
                 YPDFYPKEYVNLD 
               
               
                 428 
                 447 
                 442 
                 GRFPPIISEFSSTVDTVIDQ 
               
               
                 721 
                 742 
                 737 
                 ISQLSKGLSSKSLASEKLLLSG 
               
               
                 653 
                 662 
                 659 
                 LMKVYNIDGV 
               
               
                 10 
                 17 
                 15 
                 SKPLPSQP 
               
               
                 328 
                 335 
                 334 
                 PIWVHRWA 
               
               
                 310 
                 318 
                 313 
                 VEKHGYLFM 
               
               
                 1104 
                 1115 
                 1107 
                 VARSLKSSFQDI 
               
               
                 1074 
                 1082 
                 1077 
                 PFSLFKQNS 
               
               
                 49 
                 55 
                 51 
                 HLDLQIN 
               
               
                 257 
                 263 
                 258 
                 YTLAIEK 
               
               
                 923 
                 929 
                 923 
                 SEAVKEI 
               
               
                 821 
                 827 
                 821 
                 DFNVPAM 
               
               
                 707 
                 712 
                 707 
                 EIAVEK 
               
               
                 376 
                 381 
                 380 
                 RFCFEI 
               
               
                 100 
                 108 
                 102 
                 DQEYTVTGL 
               
               
                 745 
                 750 
                 749 
                 SSILPG 
               
               
                   
               
            
           
           
               
               
            
               
                 11. IPF9385 
                   
               
               
                 MSPDSISSSVNQDLSTPTPPTSLSSTSTNSNTNASSGQKRIRATGEALEFLISEFETNPNPSPERRKFISDK 
               
               
                   
               
               
                 AQMNEKAVRIWFQNRRAKQRKFERQMLRKETDSPGNYAGIYNTYTPNPPTVTTDMTNFNVNGSAGGATADFN 
               
               
                   
               
               
                 DKLKNISSIPVEVNEKYCFIDCRSLSVGSWQRIKTGFHQSNLLTNNLINLAPVTLNQVMSNADLLIILSKKN 
               
               
                   
               
               
                 LELNYFFSAISNNSRILFRIFYPLNAVVKCSLFDNNYYQNNNTNGTNSSDDNNISEIRLNLCQKPKFSVYFF 
               
               
                   
               
               
                 NGSNTNNQWSICDDFSEGQQVSCAFAANDNSLPSNGKNQSFSNTIPHVLVGSTLSLQYLSQFILQHQQRQRQ 
               
               
                   
               
               
                 QQRQAQPQPQPQPHNQFDFNSQPFETIPTSAINNNFNTTKTVNSSSMQGFVPGDFQDLPAIYESISNSNHTT 
               
               
                   
               
               
                 TTDLKDTNATTTTTNKHTPSSTTFTPQNLNGSNQSQTNVTYTNNYNESPFSIASTTNNNNTNSYRSNSQSHN 
               
               
                   
               
               
                 PIFSDQLFYESSESASTNSPQFAMKKMNSETKLYINGNVSSNSSTNGPPLDDDNNLFDGVTRFTTTETSPED 
               
               
                   
               
               
                 DIIGMFTSQAHEPSAFELANGVTSSGSSYTHINNGSLTKSDKTFTGLSETSNNNNNTNGINFVDDFHVGNEF 
               
               
                   
               
               
                 GDIDFEHHYSQDHHQQQQKNDNNNGNTNLDSFIDFEN* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 SPFSIASTTNNNNTNS 
                 480 
                 0.94 
               
               
                 2 
                 HHQQQQKNDNNNGNTN 
                 661 
                 0.93 
               
               
                 2 
                 SSTNGPPLDDDNNLFD 
                 547 
                 0.93 
               
               
                 2 
                 YAGIYNTYTPNPPTVT 
                 109 
                 0.93 
               
               
                 3 
                 QPQPQPHNQFDFNSQP 
                 368 
                 0.92 
               
               
                 4 
                 CQKPKFSVYFFNGSNT 
                 278 
                 0.91 
               
               
                 5 
                 SEGQQVSCAFAANDNS 
                 304 
                 0.89 
               
               
                 6 
                 TSSGSSYTHINNGSLT 
                 599 
                 0.88 
               
               
                 7 
                 RKFISDKAQMNEKAVR 
                 66 
                 0.87 
               
               
                 7 
                 MFTSQAHEPSAFELAN 
                 581 
                 0.87 
               
               
                 7 
                 SNHTTTTDLKDTNATT 
                 428 
                 0.87 
               
               
                 7 
                 GSAGGATADFNDKLKN 
                 134 
                 0.87 
               
               
                 8 
                 QMLRKETDSPGNYAGI 
                 97 
                 0.86 
               
               
                 8 
                 TFTGLSETSNNNNNTN 
                 619 
                 0.86 
               
               
                 8 
                 KCSLFDNNYYQNNNTN 
                 245 
                 0.86 
               
               
                 9 
                 TGEALEFLISEFETNP 
                 44 
                 0.85 
               
               
                 9 
                 KNISSIPVEVNEKYCF 
                 148 
                 0.85 
               
               
                 10 
                 SASTNSPQFAMKKMNS 
                 518 
                 0.84 
               
               
                 10 
                 TFTPQNLNGSNQSQTN 
                 455 
                 0.84 
               
               
                 10 
                 AFAANDNSLPSNGKNQ 
                 312 
                 0.84 
               
               
                 10 
                 VGSWQRIKTGFHQSNL 
                 171 
                 0.84 
               
               
                 11 
                 GVTRFTTTETSPEDDI 
                 563 
                 0.83 
               
               
                 11 
                 SEFETNPNPSPERRKF 
                 53 
                 0.83 
               
               
                 11 
                 LFRIFYPLNAVVKCSL 
                 233 
                 0.83 
               
               
                 11 
                 PNPPTVTTDMTNFNVN 
                 118 
                 0.83 
               
               
                 12 
                 LKDTNATTTTTNKHTP 
                 436 
                 0.82 
               
               
                 12 
                 YESISNSNHTTTTDLK 
                 422 
                 0.82 
               
               
                 12 
                 QKRIRATGEALEFLIS 
                 38 
                 0.82 
               
               
                 13 
                 HNPIFSDQLFYESSES 
                 503 
                 0.81 
               
               
                 13 
                 PFETIPTSAINNNFNT 
                 383 
                 0.81 
               
               
                 13 
                 TPPTSLSSTSTNSNTN 
                 18 
                 0.81 
               
               
                 14 
                 GNVSSNSSTNGPPLDD 
                 541 
                 0.80 
               
               
                 14 
                 TKLYINGNVSSNSSTN 
                 535 
                 0.80 
               
               
                 14 
                 SSSMQGFVPGDFQDLP 
                 404 
                 0.80 
               
               
                 15 
                 QWSICDDFSEGQQVSC 
                 296 
                 0.79 
               
               
                 15 
                 PVEVNEKYCFIDCRSL 
                 154 
                 0.79 
               
               
                 16 
                 TNSSDDNNISEIRLNL 
                 262 
                 0.77 
               
               
                 17 
                 AVRIWFQNRRAKQRKF 
                 79 
                 0.76 
               
               
                 17 
                 AFELANGVTSSGSSYT 
                 591 
                 0.76 
               
               
                 17 
                 TYTNNYNESPFSIAST 
                 472 
                 0.76 
               
               
                 17 
                 SNQSQTNVTYTNNYNE 
                 464 
                 0.76 
               
               
                 18 
                 YCFIDCRSLSVGSWQR 
                 161 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 232 
                 249 
                 246 
                 ILFRIFYPLNAVVKCSLF 
               
               
                 330 
                 355 
                 335 
                 SNTIPHVLVGSTLSLQYLSQFILQHQ 
               
               
                 306 
                 314 
                 312 
                 GQQVSCAFA 
               
               
                 149 
                 174 
                 163 
                 NISSIPVEVNEKYCFIDCRSLSVGSW 
               
               
                 204 
                 216 
                 211 
                 SNADLLIILSKKN 
               
               
                 192 
                 202 
                 194 
                 INLAPVTLNQV 
               
               
                 638 
                 646 
                 641 
                 FVDDFHVGN 
               
               
                 272 
                 288 
                 285 
                 EIRLNLCQKPKFSVYFF 
               
               
                 48 
                 54 
                 50 
                 LEFLISE 
               
               
                 218 
                 225 
                 224 
                 ELNYFFSA 
               
               
                 408 
                 425 
                 419 
                 QGFVPGDFQDLPAIYESI 
               
               
                 503 
                 516 
                 510 
                 HNPIFSDQLFYESS 
               
               
                 4 
                 13 
                 7 
                 DSISSSVNQD 
               
               
                 297 
                 303 
                 301 
                 WSICDDF 
               
               
                 480 
                 485 
                 483 
                 SPFSIA 
               
               
                 584 
                 598 
                 592 
                 SQAHEPSAFELANGV 
               
               
                 653 
                 664 
                 658 
                 FEHHYSQDHHQQ 
               
               
                 363 
                 374 
                 371 
                 RQAQPQPQPQPH 
               
               
                 20 
                 25 
                 22 
                 PTSLSS 
               
               
                 384 
                 390 
                 389 
                 FETIPTS 
               
               
                 600 
                 606 
                 605 
                 SSGSSYT 
               
               
                 118 
                 123 
                 120 
                 PNPPTV 
               
               
                 109 
                 115 
                 115 
                 YAGIYNT 
               
               
                   
               
            
           
           
               
               
            
               
                 12. IPF9413 
                   
               
               
                 MDKEYQEYQISDMPSFIGWACHGILKQNRTTSEFLLNSTQSLLFSTRLSIPTILAGLEYINQRFSNKEIYHL 
               
               
                   
               
               
                 QDQEIFQILVVSFLLSNKMNDDATFTNKSWEQASGIPLSVLNREEREWLNEVKFNLAVTKYEANISVLDQCW 
               
               
                   
               
               
                 KTWVNKYGSCHSEPPSSPTYYTPEVDAYYYSSHHHSYSSPISYSQHSYSNPYPQHQQCNYQYQYQPQYQPTY 
               
               
                   
               
               
                 QSHTQYLVPQPPPPPPPSYYDPAIVSVNYGGFIYT* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 LVPQPPPPPPPSYYDP 
                 223 
                 0.93 
               
               
                 1 
                 QPTYQSHTQYLVPQPP 
                 213 
                 0.93 
               
               
                 2 
                 GSCHSEPPSSPTYYTP 
                 152 
                 0.91 
               
               
                 3 
                 SQHSYSNPYPQHQQCN 
                 188 
                 0.90 
               
               
                 3 
                 HHSYSSPISYSQHSYS 
                 178 
                 0.90 
               
               
                 4 
                 SSPTYYTPEVDAYYYS 
                 160 
                 0.86 
               
               
                 5 
                 IPTILAGLEYINQRFS 
                 50 
                 0.84 
               
               
                 5 
                 TPEVDAYYYSSHHHSY 
                 166 
                 0.84 
               
               
                 5 
                 KSWEQASGIPLSVLNR 
                 100 
                 0.84 
               
               
                 6 
                 QILVVSFLLSNKMNDD 
                 79 
                 0.83 
               
               
                 6 
                 GILKQNRTTSEFLLNS 
                 23 
                 0.83 
               
               
                 6 
                 PSFIGWACHGILKQNR 
                 14 
                 0.83 
               
               
                 6 
                 EREWLNEVKFNLAVTK 
                 117 
                 0.83 
               
               
                 7 
                 EYQISDMPSFIGWACH 
                 7 
                 0.82 
               
               
                 8 
                 HQQCNYQYQYQPQYQP 
                 199 
                 0.81 
               
               
                 9 
                 PPPPSYYDPAIVSVNY 
                 230 
                 0.78 
               
               
                 10 
                 SVLNREEREWLNEVKF 
                 111 
                 0.77 
               
               
                 11 
                 WKTWVNKYGSCHSEPP 
                 144 
                 0.76 
               
               
                 12 
                 FNLAVTKYEANISVLD 
                 126 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 69 
                 88 
                 84 
                 IYHLQDQEIFQILVVSFLLS 
               
               
                 136 
                 143 
                 140 
                 NISVLDQC 
               
               
                 161 
                 248 
                 225 
                 SPTYYTPEVDAYYYSSHHHSYSSPISYSQHSYSNPYP 
               
               
                   
                   
                   
                 QHQQCNYQYQYQPQYQPTYQSHTQYLVPQPPPPPPPS 
               
               
                   
                   
                   
                 YYDPAIVSVNYGGF 
               
               
                 106 
                 113 
                 110 
                 SGIPLSVL 
               
               
                 123 
                 133 
                 127 
                 EVKFNLAVTKY 
               
               
                 33 
                 60 
                 51 
                 EFLLNSTQSLLFSTRLSIPTILAGLEYI 
               
               
                 17 
                 25 
                 23 
                 IGWACHGIL 
               
               
                 150 
                 159 
                 151 
                 KYGSCHSEPP 
               
               
                   
               
            
           
           
               
               
            
               
                 13. SPT6 
                   
               
               
                 MMKKKISAKKKNQQQQQLHQPTMSEVTEEERTRYEEEEDVRDSPSDSSEESEDDEEEIQKVREGFIVDDEED 
               
               
                   
               
               
                 EVQTKKRKSHKRKRDKERPHYDDALDDDDLELLLENSGLKRGSSSSGKFKRLKRKQIEDDEDEIESQDHQGE 
               
               
                   
               
               
                 QQLRDIFSDDEEVEEEAAPRIMDEFDGFIEEDDFSDEDEQTRLERREQRKKKKQGPRIDTSNLSNVDRQSLS 
               
               
                   
               
               
                 ELFEVFGDGNEYDWALEAQELEDAGAIDKEEPASLDEVFEHSELKERMLTEEDNLIRIIDVPERYQMYRSAL 
               
               
                   
               
               
                 TYIDLDDEELELEKTWVANTLLKEKKAFLRDDWVEPFKQCVGQVVQFVSKENLEVPFIWNHRRDYLEYVDPD 
               
               
                   
               
               
                 APIPGSVRELMISEDDVWRIVKLDIEYHSLYEKRLNTEKIIDSLEIDDELVKDIKTLDSMVAIQDMHDYIQF 
               
               
                   
               
               
                 TYSKEIRQREETQNRKHSKFALYERIRENVLYDAVKAYGITAKEFGENVQDQSSKGFEVPYRIHATDDPWES 
               
               
                   
               
               
                 PDDMIERLIQDDEVIFRDEKTARDAVRRTFADEIFYNPKIRHEVRSTYKLYASISVAVTEKGRASIDAHSPF 
               
               
                   
               
               
                 ADIKYAINRSPADLIAKPDVLLRMLEAERLGLVVIKVETKDFANWFDCLFNCLKSDGFSDISEKWNQERQAV 
               
               
                   
               
               
                 LRTAISRLCAVVALNTKEDLRRECERLIASKVRHGLLAKIEQAPFTPYGFDIGSKANVLALTFGKGDYDSAV 
               
               
                   
               
               
                 VGVYIKHDGKVSRFFKSTENPSRNRETEDAFKGQLKQFFDEDETPDVVVVSGYNANTKRLHDVVYNFVSEYG 
               
               
                   
               
               
                 ISVKSEFDDGSSQLVKVIWGQDETARLYQNSERAKKEFPDKPTLVKYAISLGRYLQDPLLEYITLGDDILSL 
               
               
                   
               
               
                 TFHEHQKLISNDLVKEVVESAFVDLVNAVGVDINESVRDSRLAQTLKYVGGLGPRKASGMLRNIAQKLGSVL 
               
               
                   
               
               
                 TTRSQLIEYELTTRTIFINCSAALKISLNKSINVKDFEIEILDTTRIHPEDYQLAMKMAADALDMDEESELH 
               
               
                   
               
               
                 EKGGVIKELLENDPSKLNLLNLNDFANQIYKLTHKLKFRSLQAIRLELIQGFAEIRSPFRILTNEDAFFILT 
               
               
                   
               
               
                 GEKPQMLKNTVIPATITKVTKNHHDPYARIRGLKVVTPSLIQGTIDENAIPRDAEYVQGQVVQAVVLELYTD 
               
               
                   
               
               
                 TFAAVLSLRREDISRAMKGGVVREYGKWDYKAEDEDIKREKAKENAKLAKTRNIQHPFYRNFNYKQAEEYLA 
               
               
                   
               
               
                 PQNVGDYVIRPSSKGASYLTITWKVGNNLFQHLLVEERSRGRFKEYIVDGKTYEDLDQLAFQHIQVIAKNVT 
               
               
                   
               
               
                 DMVRHPKFREGTLSVVHEWLESYTRANPKSSAYVFCYDHKSPGNFLLLFKVNVSAKVVTWHVKTEVGGYELR 
               
               
                   
               
               
                 SSVYPNMLSLCNGFKQAVKMSSQQTKSYNTGYY* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 DDPWESPDDMIERLIQ 
                 499 
                 0.95 
               
               
                 1 
                 KLDIEYHSLYEKRLNT 
                 382 
                 0.95 
               
               
                 1 
                 HHDPYARIRGLKVVTP 
                 1103 
                 0.95 
               
               
                 2 
                 PFIWNHRRDYLEYVDP 
                 344 
                 0.94 
               
               
                 2 
                 DGFIEEDDFSDEDEQT 
                 170 
                 0.94 
               
               
                 3 
                 EQAPFTPYGFDIGSKA 
                 689 
                 0.91 
               
               
                 3 
                 PSLIQGTIDENAIPRD 
                 1118 
                 0.91 
               
               
                 4 
                 EERTRYEEEEDVRDSP 
                 29 
                 0.90 
               
               
                 4 
                 LSVVHEWLESYTRANP 
                 1309 
                 0.90 
               
               
                 5 
                 AFKGQLKQFFDEDETP 
                 750 
                 0.89 
               
               
                 5 
                 TEKIIDSLEIDDELVK 
                 397 
                 0.89 
               
               
                 5 
                 AFLRDDWVEPFKQCVG 
                 315 
                 0.89 
               
               
                 5 
                 YQMYRSALTYIDLDDE 
                 281 
                 0.89 
               
               
                 5 
                 DWALEAQELEDAGAID 
                 229 
                 0.89 
               
               
                 5 
                 GGVVREYGKWDYKAED 
                 1171 
                 0.89 
               
               
                 5 
                 TITKVTKNHHDPYARI 
                 1095 
                 0.89 
               
               
                 5 
                 AFFILTGEKPQMLKNT 
                 1075 
                 0.89 
               
               
                 6 
                 YERIRENVLYDAVKAY 
                 455 
                 0.88 
               
               
                 6 
                 KGASYLTITWKVGNNL 
                 1238 
                 0.88 
               
               
                 6 
                 GGVIKELLENDPSKLN 
                 1011 
                 0.88 
               
               
                 7 
                 RIHPEDYQLAMKMAAD 
                 982 
                 0.87 
               
               
                 7 
                 LVKVIWGQDETARLYQ 
                 806 
                 0.87 
               
               
                 7 
                 ERLIASKVRHGLLAKI 
                 673 
                 0.87 
               
               
                 7 
                 GPRIDTSNLSNVDRQS 
                 199 
                 0.87 
               
               
                 7 
                 DEDEQTRLERREQRKK 
                 180 
                 0.87 
               
               
                 7 
                 TRNIQHPFYRNFNYKQ 
                 1203 
                 0.87 
               
               
                 8 
                 SQLIEYELTTRTIFIN 
                 940 
                 0.86 
               
               
                 8 
                 DETPDVVVVSGYNANT 
                 762 
                 0.86 
               
               
                 8 
                 AHSPFADIKYAINRSP 
                 572 
                 0.86 
               
               
                 8 
                 KAYGITAKEFGENVQD 
                 468 
                 0.86 
               
               
                 8 
                 ELMISEDDVWRIVKLD 
                 369 
                 0.86 
               
               
                 8 
                 HLLVEERSRGRFKEYI 
                 1256 
                 0.86 
               
               
                 9 
                 TLVKYAISLGRYLQDP 
                 835 
                 0.85 
               
               
                 9 
                 KKRKSHKRKRDKERPH 
                 77 
                 0.85 
               
               
                 9 
                 KGDYDSAVVGVYIKHD 
                 713 
                 0.85 
               
               
                 9 
                 SKANVLALTFGKGDYD 
                 702 
                 0.85 
               
               
                 9 
                 LRTAISRLCAVVALNT 
                 649 
                 0.85 
               
               
                 9 
                 ADEIFYNPKIRHEVRS 
                 535 
                 0.85 
               
               
                 9 
                 DELVKDIKTLDSMVAI 
                 408 
                 0.85 
               
               
                 9 
                 PRIMDEFDGFIEEDDF 
                 163 
                 0.85 
               
               
                 10 
                 RPHYDDALDDDDLELL 
                 90 
                 0.84 
               
               
                 10 
                 VETKDFANWFDCLFNC 
                 613 
                 0.84 
               
               
                 10 
                 DEEEIQKVREGFIVDD 
                 54 
                 0.84 
               
               
                 10 
                 SEESEDDEEEIQKVRE 
                 48 
                 0.84 
               
               
                 10 
                 VEEEAAPRIMDEFDGF 
                 157 
                 0.84 
               
               
                 11 
                 EYGISVKSEFDDGSSQ 
                 790 
                 0.83 
               
               
                 11 
                 EVPYRIHATDDPWESP 
                 490 
                 0.83 
               
               
                 11 
                 RRDYLEYVDPDAPIPG 
                 350 
                 0.83 
               
               
                 12 
                 ARLYQNSERAKKEFPD 
                 817 
                 0.82 
               
               
                 12 
                 KVSRFFKSTENPSRNR 
                 730 
                 0.82 
               
               
                 12 
                 EGFIVDDEEDEVQTKK 
                 63 
                 0.82 
               
               
                 12 
                 DDEVIFRDEKTARDAV 
                 515 
                 0.82 
               
               
                 12 
                 TWHVKTEVGGYELRSS 
                 1355 
                 0.82 
               
               
                 12 
                 KAEDEDIKREKAKENA 
                 1183 
                 0.82 
               
               
                 13 
                 MKMAADALDMDEESEL 
                 992 
                 0.81 
               
               
                 13 
                 YASISVAVTEKGRASI 
                 555 
                 0.81 
               
               
                 13 
                 NPKIRHEVRSTYKLYA 
                 541 
                 0.81 
               
               
                 13 
                 QSSKGFEVPYRIHATD 
                 484 
                 0.81 
               
               
                 13 
                 FEVFGDGNEYDWALEA 
                 219 
                 0.81 
               
               
                 13 
                 YVFCYDHKSPGNFLLL 
                 1329 
                 0.81 
               
               
                 13 
                 KEYIVDGKTYEDLDQL 
                 1268 
                 0.81 
               
               
                 14 
                 GVDINESVRDSRLAQT 
                 894 
                 0.80 
               
               
                 14 
                 KQFFDEDETPDVVVVS 
                 756 
                 0.80 
               
               
                 14 
                 QGFAEIRSPFRILTNE 
                 1058 
                 0.80 
               
               
                 15 
                 RREQRKKKKQGPRIDT 
                 189 
                 0.79 
               
               
                 15 
                 ESYTRANPKSSAYVFC 
                 1317 
                 0.79 
               
               
                 15 
                 HIQVIAKNVTDMVRHP 
                 1287 
                 0.79 
               
               
                 15 
                 YGKWDYKAEDEDIKRE 
                 1177 
                 0.79 
               
               
                 15 
                 AIPRDAEYVQGQVVQA 
                 1129 
                 0.79 
               
               
                 16 
                 EIEILDTTRIHPEDYQ 
                 974 
                 0.78 
               
               
                 16 
                 VVSGYNANTKRLHDVV 
                 769 
                 0.78 
               
               
                 16 
                 IRIIDVPERYQMYRSA 
                 272 
                 0.78 
               
               
                 16 
                 RDIFSDDEEVEEEAAP 
                 148 
                 0.78 
               
               
                 17 
                 RKRDKERPHYDDALDD 
                 84 
                 0.77 
               
               
                 17 
                 EEDVRDSPSDSSEESE 
                 37 
                 0.77 
               
               
                 17 
                 DYVIRPSSKGASYLTI 
                 1230 
                 0.77 
               
               
                 18 
                 CLKSDGFSDISEKWNQ 
                 628 
                 0.76 
               
               
                 18 
                 KRKQIEDDEDEIESQD 
                 125 
                 0.76 
               
               
                 19 
                 DISEKWNQERQAVLRT 
                 636 
                 0.75 
               
               
                 19 
                 RQREETQNRKHSKFAL 
                 439 
                 0.75 
               
               
                 19 
                 QFTYSKEIRQREETQN 
                 431 
                 0.75 
               
               
                 19 
                 KQCVGQVVQFVSKENL 
                 326 
                 0.75 
               
               
                 19 
                 IESQDHQGEQQLRDIF 
                 136 
                 0.75 
               
               
                 19 
                 LRREDISRAMKGGVVR 
                 1160 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 1133 
                 1160 
                 1144 
                 DAEYVQGQVVQAVVLELYTDTFAAVLSL 
               
               
                 646 
                 663 
                 659 
                 QAVLRTAISRLCAVVALN 
               
               
                 765 
                 773 
                 770 
                 PDVVVVSGY 
               
               
                 322 
                 346 
                 330 
                 VEPFKQCVGQVVQFVSKENLEVPFI 
               
               
                 717 
                 734 
                 722 
                 DSAVVGVYIKHDGKVSRF 
               
               
                 604 
                 614 
                 610 
                 ERLGLVVIKVE 
               
               
                 1254 
                 1261 
                 1256 
                 FQHLLVEE 
               
               
                 1326 
                 1336 
                 1330 
                 SSAYVFCYDHK 
               
               
                 1340 
                 1357 
                 1344 
                 NFLLLFKVNVSAKVVTWH 
               
               
                 780 
                 797 
                 786 
                 LHDVVYNFVSEYGISVKS 
               
               
                 833 
                 896 
                 884 
                 KPTLVKYAISLGRYLQDPLLEYITLGDDILSLTFHEH 
               
               
                   
                   
                   
                 QKLISNDLVKEVVESAFVDLVNAVGVD 
               
               
                 1104 
                 1123 
                 1118 
                 HDPYARIRGLKVVTPSLIQG 
               
               
                 804 
                 812 
                 807 
                 SQLVKVIWG 
               
               
                 621 
                 632 
                 627 
                 WFDCLFNCLKSD 
               
               
                 545 
                 563 
                 559 
                 RHEVRSTYKLYASISVAVT 
               
               
                 460 
                 472 
                 465 
                 ENVLYDAVKAYGI 
               
               
                 1308 
                 1316 
                 1310 
                 TLSVVHEWL 
               
               
                 1280 
                 1294 
                 1288 
                 LDQLAFQHIQVIAKN 
               
               
                 953 
                 965 
                 959 
                 FINCSAALKISLN 
               
               
                 378 
                 393 
                 380 
                 WRIVKLDIEYHSLYEK 
               
               
                 272 
                 280 
                 274 
                 IRIIDVPER 
               
               
                 703 
                 710 
                 709 
                 KANVLALT 
               
               
                 588 
                 600 
                 595 
                 ADLIAKPDVLLRM 
               
               
                 488 
                 496 
                 494 
                 GFEVPYRIH 
               
               
                 673 
                 699 
                 683 
                 ERLIASKVRHGLLAKIEQAPFTPYGFD 
               
               
                 1367 
                 1389 
                 1370 
                 LRSSVYPNMLSLCNGFKQAVKMS 
               
               
                 353 
                 370 
                 356 
                 YLEYVDPDAPIPGSVREL 
               
               
                 907 
                 916 
                 913 
                 AQTLKYVGGL 
               
               
                 928 
                 946 
                 933 
                 IAQKLGSVLTTRSQLIEYE 
               
               
                 1219 
                 1235 
                 1225 
                 AEEYLAPQNVGDYVIRP 
               
               
                 215 
                 222 
                 218 
                 LSELFEVF 
               
               
                 284 
                 293 
                 290 
                 YRSALTYIDL 
               
               
                 1088 
                 1098 
                 1093 
                 KNTVIPATITK 
               
               
                 1035 
                 1060 
                 1051 
                 NQIYKLTHKLKFRSLQAIRLELIQGF 
               
               
                 450 
                 457 
                 452 
                 SKFALYER 
               
               
                 58 
                 68 
                 64 
                 IQKVREGFIVD 
               
               
                 102 
                 108 
                 103 
                 LELLLEN 
               
               
                 418 
                 424 
                 420 
                 DSMVAIQ 
               
               
                 251 
                 258 
                 257 
                 LDEVFEHS 
               
               
                 15 
                 21 
                 18 
                 QQQLHQP 
               
               
                 1239 
                 1247 
                 1243 
                 GASYLTITW 
               
               
                 1171 
                 1176 
                 1176 
                 GGVVRE 
               
               
                 1269 
                 1274 
                 1269 
                 EYIVDG 
               
               
                 1076 
                 1081 
                 1078 
                 FFILTG 
               
               
                 407 
                 414 
                 413 
                 DDELVKDI 
               
               
                 570 
                 582 
                 580 
                 IDAHSPFADIKYA 
               
               
                 515 
                 521 
                 515 
                 DDEVIFR 
               
               
                 1296 
                 1302 
                 1298 
                 TDMVRHP 
               
               
                 985 
                 991 
                 987 
                 PEDYQLA 
               
               
                 752 
                 758 
                 756 
                 KGQLKQF 
               
               
                   
               
            
           
           
               
               
            
               
                 14. SET1 
                   
               
               
                 MSYNNRSGGGASGGYSRRGYHGSHRGGYRTGRSKYPEDRYLVGGMLSLNKGSHYESSDNRYIPNEIGSKSPE 
               
               
                   
               
               
                 NRSHRSSTKDGRTPSGLSTPLSSSDKVSTPISIESINGSDRNTGVNNKDSEFPKLSHHSDFTSTIPFSRSIN 
               
               
                   
               
               
                 PQKNFMVINDSHTPKTDKGIQSKKIRYNGEGVNHVSDPRIAQSNSNLQKPTKKTKKTPYKQLPQPKFVYNSD 
               
               
                   
               
               
                 SLGPAPMSTIIIWDLPISTSEPFLRNFVSRYGNPLEEMTFITDPTTAVPLGIVTFKFQGNPQKASELAKNFI 
               
               
                   
               
               
                 KTVRQDELKIDGATLKIALNDNENQLLNRKLESAKKKMLQQRLQREQEEEKRRQKLVEEQKKQELLKKKEKE 
               
               
                   
               
               
                 HQESVKKEKSVEHESTIVSTRDKNLVYKPNSTVLSMRHNHKIISSVILPKDLEKYIKSRPYILIRDKYVPTK 
               
               
                   
               
               
                 KISSHDIKRALKKYDWTRVLSDKSGFFIVFNSLNECERCFLNEDNKKFFEYKLVMEMAIPEGFTNNIRENES 
               
               
                   
               
               
                 KSTNDVLDEATNILIKEFQTFLAKDIRERIIAPNILDLLAHDKYPELVEELKSREQAAKPKVLVTNNQLKEN 
               
               
                   
               
               
                 ALSILEKQRQLFQQRLPSFRMSHDRTQQHKPKRRNSIIPMQHALNFDDDEDSESHSQSESEDEDEDETTASR 
               
               
                   
               
               
                 PLTPVVSTMKRERSSTITSIEDDIELEEREIKKQKVKVPAIEAEIAPESSPEEGEEEEKEEVEIKQEAEEVD 
               
               
                   
               
               
                 IKFQPTEESPRTVYPEIPFSGDFDLNALQHTIKDSEDLLLAQEVLSETTPSGLSNIEYWSWKSKNRKDVQEI 
               
               
                   
               
               
                 SQEEEYIEELPESLQSTTGSFKSEGVRKIPEIEKIGYLPHRKRTNKPIKTIQYEDEDEEKPNENTNAVQSSR 
               
               
                   
               
               
                 VNRANNRRFAADITAQIGSESDVLSLNALTKRKKPVTFARSAIHNWGLYAMEPIAAKEMIIEYVGERIRQQV 
               
               
                   
               
               
                 AEHREKSYLKTGIGSSYLFRIDDNTVIDATKKGGIARFINHCCSPSCTAKIIKVEGKKRIVIYALRDIEANE 
               
               
                   
               
               
                 ELTYDYKFERETNDEERIRCLCGAPGCKGYLN* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 KEMIIEYVGERIRQQV 
                 921 
                 0.94 
               
               
                 1 
                 EIEKIGYLPHRKRTNK 
                 823 
                 0.94 
               
               
                 1 
                 DRTQQHKPKRRNSIIP 
                 600 
                 0.94 
               
               
                 2 
                 YPEIPFSGDFDLNALQ 
                 734 
                 0.93 
               
               
                 2 
                 VEIKQEAEEVDIKFQP 
                 710 
                 0.93 
               
               
                 2 
                 SKKIRYNGEGVNHVSD 
                 166 
                 0.93 
               
               
                 2 
                 TSTIPFSRSINPQKNF 
                 134 
                 0.93 
               
               
                 3 
                 KTGIGSSYLFRIDDNT 
                 946 
                 0.92 
               
               
                 3 
                 SGLSTPLSSSDKVSTP 
                 87 
                 0.92 
               
               
                 3 
                 YILIRDKYVPTKKISS 
                 421 
                 0.92 
               
               
                 3 
                 GSHRGGYRTGRSKYPE 
                 22 
                 0.92 
               
               
                 3 
                 SIESINGSDRNTGVNN 
                 104 
                 0.92 
               
               
                 4 
                 KKRIVIYALRDIEANE 
                 993 
                 0.91 
               
               
                 4 
                 DEDEEKPNENTNAVQS 
                 847 
                 0.91 
               
               
                 4 
                 IKTIQYEDEDEEKPNE 
                 840 
                 0.91 
               
               
                 5 
                 YWSWKSKNRKDVQEIS 
                 778 
                 0.90 
               
               
                 6 
                 ESTIVSTRDKNLVYKP 
                 374 
                 0.88 
               
               
                 7 
                 RERIIAPNILDLLAHD 
                 531 
                 0.87 
               
               
                 8 
                 NEIGSKSPENRSHRSS 
                 64 
                 0.86 
               
               
                 8 
                 SHSQSESEDEDEDETT 
                 630 
                 0.86 
               
               
                 8 
                 NILIKEFQTFLAKDIR 
                 516 
                 0.86 
               
               
                 9 
                 RSSTKDGRTPSGLSTP 
                 77 
                 0.85 
               
               
                 9 
                 DEDETTASRPLTPVVS 
                 640 
                 0.85 
               
               
                 9 
                 KGSHYESSDNRYIPNE 
                 50 
                 0.85 
               
               
                 9 
                 EMAIPEGFTNNIRENE 
                 488 
                 0.85 
               
               
                 9 
                 TGRSKYPEDRYLVGGM 
                 30 
                 0.85 
               
               
                 10 
                 LFRIDDNTVIDATKKG 
                 954 
                 0.84 
               
               
                 10 
                 VQEISQEEEYIEELPE 
                 789 
                 0.84 
               
               
                 10 
                 AQEVLSETTPSGLSNI 
                 761 
                 0.84 
               
               
                 10 
                 KKKEKEHQESVKKEKS 
                 355 
                 0.84 
               
               
                 10 
                 TAVPLGIVTFKFQGNP 
                 262 
                 0.84 
               
               
                 11 
                 TKKGGIARFINHCCSP 
                 966 
                 0.83 
               
               
                 11 
                 MTFITDPTTAVPLGIV 
                 254 
                 0.83 
               
               
                 11 
                 MSTIIIWDLPISTSEP 
                 223 
                 0.83 
               
               
                 11 
                 FMVINDSHTPKTDKGI 
                 149 
                 0.83 
               
               
                 12 
                 GGGASGGYSRRGYHGS 
                 8 
                 0.82 
               
               
                 12 
                 EELTYDYKFERETNDE 
                 1008 
                 0.82 
               
               
                 13 
                 NTVIDATKKGGIARFI 
                 960 
                 0.81 
               
               
                 13 
                 ESLQSTTGSFKSEGVR 
                 804 
                 0.81 
               
               
                 13 
                 ESSPEEGEEEEKEEVE 
                 696 
                 0.81 
               
               
                 13 
                 SRSINPQKNFMVINDS 
                 140 
                 0.81 
               
               
                 14 
                 KRERSSTITSIEDDIE 
                 658 
                 0.80 
               
               
                 14 
                 PVVSTMKRERSSTITS 
                 652 
                 0.80 
               
               
                 15 
                 DITAQIGSESDVLSLN 
                 876 
                 0.79 
               
               
                 15 
                 TPSGLSNIEYWSWKSK 
                 769 
                 0.79 
               
               
                 15 
                 KSREQAAKPKVLVTNN 
                 556 
                 0.79 
               
               
                 15 
                 KPTKKTKKTPYKQLPQ 
                 193 
                 0.79 
               
               
                 16 
                 TNAVQSSRVNRANNRR 
                 857 
                 0.78 
               
               
                 16 
                 EVDIKFQPTEESPRTV 
                 718 
                 0.78 
               
               
                 16 
                 AIEAEIAPESSPEEGE 
                 688 
                 0.78 
               
               
                 16 
                 PKRRNSIIPMQHALNF 
                 607 
                 0.78 
               
               
                 17 
                 QPTEESPRTVYPEIPF 
                 724 
                 0.77 
               
               
                 17 
                 EEEEKEEVEIKQEAEE 
                 703 
                 0.77 
               
               
                 17 
                 NSLNECERCFLNEDNK 
                 463 
                 0.77 
               
               
                 17 
                 TVRQDELKIDGATLKI 
                 290 
                 0.77 
               
               
                 17 
                 VSRYGNPLEEMTFITD 
                 244 
                 0.77 
               
               
                 17 
                 NGEGVNHVSDPRIAQS 
                 172 
                 0.77 
               
               
                 18 
                 AIHNWGLYAMEPIAAK 
                 906 
                 0.76 
               
               
                 18 
                 DLPISTSEPFLRNFVS 
                 230 
                 0.76 
               
               
                 18 
                 PYKQLPQPKFVYNSDS 
                 202 
                 0.76 
               
               
                 19 
                 PELVEELKSREQAAKP 
                 549 
                 0.75 
               
               
                 19 
                 TRVLSDKSGFFIVFNS 
                 449 
                 0.75 
               
               
                 19 
                 LQREQEEEKRRQKLVE 
                 331 
                 0.75 
               
               
                 19 
                 FERETNDEERIRCLCG 
                 1016 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 974 
                 991 
                 980 
                 FINHCCSPSCTAKIIKVE 
               
               
                 261 
                 272 
                 266 
                 TTAVPLGIVTFK 
               
               
                 400 
                 415 
                 405 
                 HKIISSVILPKDLEKY 
               
               
                 647 
                 656 
                 652 
                 SRPLTPVVST 
               
               
                 756 
                 768 
                 761 
                 EDLLLAQEVLSET 
               
               
                 1026 
                 1037 
                 1029 
                 IRCLCGAPGCKG 
               
               
                 995 
                 1003 
                 998 
                 RIVIYALRD 
               
               
                 563 
                 571 
                 565 
                 KPKVLVTNN 
               
               
                 884 
                 893 
                 890 
                 ESDVLSLNAL 
               
               
                 536 
                 555 
                 542 
                 APNILDLLAHDKYPELVEEL 
               
               
                 681 
                 692 
                 686 
                 KQKVKVPAIEAE 
               
               
                 203 
                 215 
                 209 
                 YKQLPQPKFVYNS 
               
               
                 731 
                 738 
                 736 
                 RTVYPEIP 
               
               
                 482 
                 489 
                 483 
                 EYKLVMEM 
               
               
                 457 
                 465 
                 462 
                 GFFIVFNSL 
               
               
                 467 
                 474 
                 470 
                 ECERCFLN 
               
               
                 88 
                 106 
                 102 
                 GLSTPLSSSDKVSTPISIE 
               
               
                 417 
                 437 
                 421 
                 KSRPYILIRDKYVPTKKISSH 
               
               
                 299 
                 306 
                 304 
                 DGATLKIA 
               
               
                 38 
                 45 
                 43 
                 DRYLVGGM 
               
               
                 176 
                 184 
                 179 
                 VNHVSDPRI 
               
               
                 384 
                 396 
                 388 
                 NLVYKPNSTVLSM 
               
               
                 575 
                 593 
                 590 
                 ENALSILEKQRQLFQQRLP 
               
               
                 124 
                 132 
                 127 
                 FPKLSHHSD 
               
               
                 951 
                 956 
                 952 
                 SSYLFR 
               
               
                 827 
                 833 
                 829 
                 IGYLPHR 
               
               
                 223 
                 238 
                 229 
                 MSTIIIWDLPISTSEP 
               
               
                 241 
                 248 
                 241 
                 RNFVSRYG 
               
               
                 718 
                 724 
                 722 
                 EVDIKFQ 
               
               
                 615 
                 621 
                 617 
                 PMQHALN 
               
               
                 800 
                 806 
                 805 
                 EELPESL 
               
               
                 516 
                 528 
                 520 
                 NILIKEFQTFLAK 
               
               
                 745 
                 751 
                 750 
                 LNALQHT 
               
               
                 925 
                 931 
                 927 
                 IEYVGER 
               
               
                 372 
                 380 
                 376 
                 EHESTIVST 
               
               
                 897 
                 906 
                 902 
                 KKPVTFARSA 
               
               
                 933 
                 939 
                 934 
                 RQQVAEH 
               
               
                 135 
                 140 
                 140 
                 STIPES 
               
               
                 448 
                 455 
                 449 
                 WTRVLSDK 
               
               
                 342 
                 347 
                 345 
                 QKLVEE 
               
               
                 942 
                 948 
                 946 
                 KSYLKTG 
               
               
                 439 
                 445 
                 440 
                 IKRALKK 
               
               
                 875 
                 880 
                 878 
                 ADITAQ 
               
               
                   
               
            
           
           
               
               
            
               
                 15. SAS3 
                   
               
               
                 MVSHLLNQLKITNNHIYSNIVPQDLDKRTIRAKPTNDYSLKSMIKNNTHQKSTIPITNTTKIKSVHDDSNSN 
               
               
                   
               
               
                 IKRVKRSFKHNNIFVKLTKKKCIVVINYDKTKLSTITRSKLDTVPLLPNSTSFTSENQNQNQVDTSILSEIQ 
               
               
                   
               
               
                 LPYKGILKYPDCIINDTDPTKLDTERFNKYLDEGIKLRNKTTCHLETETETETETETKTEIETELQSQVFSN 
               
               
                   
               
               
                 LLHPILNESNQSTESTPVPNYSNLNKSKINRIVLRDFEINTWYIAPYPEEYSQCEVLYICEYCLKYMNSPMS 
               
               
                   
               
               
                 YRRHQLKNCNFSNNHPPGLEIYRDQKSKISIWEVDGRKNINYCQNLCLLAKLFLNSKTLYYDVEPFIFYVLT 
               
               
                   
               
               
                 EIDEKNPSNYHFVGYFSKEKLNSSDYNVSCILTLPIYQRKGYGNLLIDFSYLLSRNEFKYGTPEKPLSDLGL 
               
               
                   
               
               
                 LSYRNYWKVTIAYKLKQIYDKYFSCNANGDGDSVSDNARLSLSIDTLCKLTGMIPSDVIVGLEQLDSLARNP 
               
               
                   
               
               
                 ITHNYAIVINLDKINTEIAKWEKKSYTKLVYEKLLWKPMLFGPSGGINSAPSIQPPQPQSTSVTTTTMSARE 
               
               
                   
               
               
                 GTTNSHPKPVIPQNSISLITNFLKDDINNPYTFEEEGFKEIEAHRETENEEIKNASLVEYVTCYPGIVVNNH 
               
               
                   
               
               
                 FVNGGGGSGESNGSNDQIKGHKKMLKKRKRIIDDDDDDDDDDDDDDDEIEKIFEIDEIPSNDENEPDFEDDS 
               
               
                   
               
               
                 DDVDDFMDDDEEEVVEIKDNDSDEDVSEDIIEILDDDDQEEEDWRRTWKRRVPSPPKRKTVNVLTGNNNKPR 
               
               
                   
               
               
                 GRGRPRGTFKLKA* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 KRTIRAKPTNDYSLKS 
                 27 
                 0.95 
               
               
                 1 
                 DPTKLDTERFNKYLDE 
                 162 
                 0.95 
               
               
                 2 
                 KRIIDDDDDDDDDDDD 
                 677 
                 0.94 
               
               
                 2 
                 QSTSVTTTTMSAREGT 
                 563 
                 0.94 
               
               
                 2 
                 PDCIINDTDPTKLDTE 
                 154 
                 0.94 
               
               
                 3 
                 QSTESTPVPNYSNLNK 
                 227 
                 0.93 
               
               
                 4 
                 QEEEDWRRTWKRRVPS 
                 759 
                 0.92 
               
               
                 4 
                 APSIQPPQPQSTSVTT 
                 554 
                 0.92 
               
               
                 4 
                 LSEIQLPYKGILKYPD 
                 140 
                 0.92 
               
               
                 5 
                 EGTTNSHPKPVIPQNS 
                 576 
                 0.91 
               
               
                 6 
                 DFEDDSDDVDDFMDDD 
                 715 
                 0.90 
               
               
                 7 
                 IFEIDEIPSNDENEPD 
                 700 
                 0.89 
               
               
                 7 
                 EPFIFYVLTEIDEKNP 
                 352 
                 0.89 
               
               
                 7 
                 KGILKYPDCIINDTDP 
                 148 
                 0.89 
               
               
                 8 
                 NTWYIAPYPEEYSQCE 
                 256 
                 0.88 
               
               
                 9 
                 SLVEYVTCYPGIVVNN 
                 632 
                 0.87 
               
               
                 9 
                 KSVHDDSNSNIKRVKR 
                 63 
                 0.87 
               
               
                 9 
                 MNSPMSYRRHQLKNCN 
                 283 
                 0.87 
               
               
                 9 
                 KSKINRIVLRDFEINT 
                 242 
                 0.87 
               
               
                 10 
                 EKKSYTKLVYEKLLWK 
                 526 
                 0.86 
               
               
                 10 
                 KLKQIYDKYFSCNANG 
                 446 
                 0.86 
               
               
                 11 
                 LETETETETETETKTE 
                 189 
                 0.85 
               
               
                 12 
                 KPRGRGRPRGTFKLKA 
                 790 
                 0.84 
               
               
                 12 
                 FKEIEAHRETENEEIK 
                 614 
                 0.84 
               
               
                 12 
                 HQKSTIPITNTTKIKS 
                 49 
                 0.84 
               
               
                 12 
                 KPTNDYSLKSMIKNNT 
                 33 
                 0.84 
               
               
                 13 
                 SGESNGSNDQIKGHKK 
                 656 
                 0.83 
               
               
                 13 
                 HLLNQLKITNNHIYSN 
                 4 
                 0.83 
               
               
                 13 
                 PYPEEYSQCEVLYICE 
                 262 
                 0.83 
               
               
                 14 
                 EVVEIKDNDSDEDVSE 
                 733 
                 0.82 
               
               
                 14 
                 EEIKNASLVEYVTCYP 
                 626 
                 0.82 
               
               
                 14 
                 QKSKISIWEVDGRKNI 
                 313 
                 0.82 
               
               
                 15 
                 CEVLYICEYCLKYMNS 
                 270 
                 0.81 
               
               
                 16 
                 EDIIEILDDDDQEEED 
                 748 
                 0.80 
               
               
                 16 
                 YFSCNANGDGDSVSDN 
                 454 
                 0.80 
               
               
                 17 
                 RRTWKRRVPSPPKRKT 
                 765 
                 0.79 
               
               
                 17 
                 FGPSGGINSAPSIQPP 
                 545 
                 0.79 
               
               
                 17 
                 KTEIETELQSQVFSNL 
                 202 
                 0.79 
               
               
                 18 
                 GLEQLDSLARNPITHN 
                 493 
                 0.78 
               
               
                 18 
                 SLSIDTLCKLTGMIPS 
                 473 
                 0.78 
               
               
                 18 
                 SCILTLPIYQRKGYGN 
                 389 
                 0.78 
               
               
                 18 
                 NIVPQDLDKRTIRAKP 
                 19 
                 0.78 
               
               
                 18 
                 DKTKLSTITRSKLDTV 
                 101 
                 0.78 
               
               
                 19 
                 EKLLWKPMLFGPSGGI 
                 536 
                 0.77 
               
               
                 19 
                 RNPITHNYAIVINLDK 
                 502 
                 0.77 
               
               
                 19 
                 KVTIAYKLKQIYDKYF 
                 440 
                 0.77 
               
               
                 19 
                 EFKYGTPEKPLSDLGL 
                 417 
                 0.77 
               
               
                 19 
                 PGLEIYRDQKSKISIW 
                 305 
                 0.77 
               
               
                 20 
                 DDDDDDDDDDDEIEKI 
                 685 
                 0.76 
               
               
                 20 
                 SISLITNFLKDDINNP 
                 591 
                 0.76 
               
               
                 20 
                 DSVSDNARLSLSIDTL 
                 464 
                 0.76 
               
               
                 20 
                 KSMIKNNTHQKSTIPI 
                 41 
                 0.76 
               
               
                 20 
                 YFSKEKLNSSDYNVSC 
                 375 
                 0.76 
               
               
                 20 
                 ERFNKYLDEGIKLRNK 
                 169 
                 0.76 
               
               
                 21 
                 LQSQVFSNLLHPILNE 
                 209 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 258 
                 283 
                 273 
                 WYIAPYPEEYSQCEVLYICEYCLKYM 
               
               
                 630 
                 648 
                 642 
                 NASLVEYVTCYPGIVVNNH 
               
               
                 84 
                 100 
                 97 
                 NIFVKLTKKKCIVVINY 
               
               
                 328 
                 361 
                 337 
                 INYCQNLCLLAKLFLNSKTLYYDVEPFIFYVLTE 
               
               
                 386 
                 399 
                 391 
                 YNVSCILTLPIYQR 
               
               
                 530 
                 542 
                 536 
                 YTKLVYEKLLWKP 
               
               
                 487 
                 500 
                 489 
                 PSDVIVGLEQLDSL 
               
               
                 113 
                 122 
                 116 
                 LDTVPLLPNS 
               
               
                 507 
                 515 
                 512 
                 HNYAIVINL 
               
               
                 210 
                 222 
                 216 
                 QSQVFSNLLHPIL 
               
               
                 370 
                 376 
                 373 
                 YHFVGYF 
               
               
                 471 
                 485 
                 477 
                 RLSLSIDTLCKLTGM 
               
               
                 440 
                 458 
                 444 
                 KVTIAYKLKQIYDKYFSCN 
               
               
                 136 
                 159 
                 154 
                 DTSILSEIQLPYKGILKYPDCIIN 
               
               
                 4 
                 9 
                 5 
                 HLLNQL 
               
               
                 403 
                 415 
                 408 
                 GNLLIDFSYLLSR 
               
               
                 583 
                 597 
                 585 
                 PKPVIPQNSISLITN 
               
               
                 425 
                 436 
                 430 
                 KPLSDLGLLSYR 
               
               
                 17 
                 24 
                 18 
                 YSNIVPQD 
               
               
                 246 
                 252 
                 247 
                 NRIVLRD 
               
               
                 554 
                 567 
                 557 
                 APSIQPPQPQSTSV 
               
               
                 231 
                 237 
                 237 
                 STPVPNY 
               
               
                 62 
                 68 
                 63 
                 IKSVHDD 
               
               
                 732 
                 737 
                 736 
                 EEVVEI 
               
               
                 316 
                 321 
                 319 
                 KISIWE 
               
               
                 748 
                 754 
                 752 
                 EDIIEIL 
               
               
                   
               
            
           
           
               
               
            
               
                 16. RPC53 
                   
               
               
                 MSNRLESLNPRKPVSSSSSSGSKSAAKFKPKVVQRKSKEERAKVAPTIKQEPQPRQPLPNSRGRGGARGRGG 
               
               
                   
               
               
                 RNNYAGTHMVSNGFLSAGAVSIGNSSGSKLGLTSDMIYNSNGDLSSSSTPDFIANFKSKQKGSTPGGQSDEE 
               
               
                   
               
               
                 DEDDDPTKINMTQKYRFNEEDTVLFPVRPFRDDGITRAENEIAMPDVEIKQEPNDSTAGSTPMPISLTQSRE 
               
               
                   
               
               
                 TTVKSELIEEKIEQIKETKSKLEKKIAQGGDSFVSEETDKVISDHQQILDILTGKFDKLSTKTEDSHQKQQT 
               
               
                   
               
               
                 QKDDVDDIDVELENDKTEINFDDQYVLFQLPKHLPTYTQPPSAVKLEPGVQSVEVDEPATEEKEISKLATNN 
               
               
                   
               
               
                 SKLRGKIGKINIHQSGKITIDLGNDIRLNVTKGAPTDFLQELALIEINPPPKPEDNEEEDVQMVDDDGRSIT 
               
               
                   
               
               
                 GKVVRLGTVNDKIIATPCIQ* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 VEIKQEPNDSTAGSTP 
                 191 
                 0.96 
               
               
                 2 
                 KVVQRKSKEERAKVAP 
                 31 
                 0.93 
               
               
                 3 
                 SGKITIDLGNDIRLNV 
                 375 
                 0.92 
               
               
                 4 
                 SSGSKLGLTSDMIYNS 
                 97 
                 0.91 
               
               
                 4 
                 NGDLSSSSTPDFIANF 
                 113 
                 0.91 
               
               
                 5 
                 GRSITGKVVRLGTVND 
                 428 
                 0.89 
               
               
                 5 
                 KKIAQGGDSFVSEETD 
                 240 
                 0.89 
               
               
                 6 
                 APTIKQEPQPRQPLPN 
                 45 
                 0.88 
               
               
                 6 
                 SVEVDEPATEEKEISK 
                 340 
                 0.88 
               
               
                 7 
                 NSRGRGGARGRGGRNN 
                 60 
                 0.87 
               
               
                 7 
                 LALIEINPPPKPEDNE 
                 402 
                 0.87 
               
               
                 7 
                 NVTKGAPTDFLQELAL 
                 389 
                 0.87 
               
               
                 7 
                 SELIEEKIEQIKETKS 
                 221 
                 0.87 
               
               
                 8 
                 AVSIGNSSGSKLGLTS 
                 91 
                 0.86 
               
               
                 8 
                 STPGGQSDEEDEDDDP 
                 135 
                 0.86 
               
               
                 9 
                 EEDEDDDPTKINMTQK 
                 143 
                 0.85 
               
               
                 10 
                 GGRNNYAGTHMVSNGF 
                 71 
                 0.84 
               
               
                 10 
                 VQMVDDDGRSITGKVV 
                 421 
                 0.84 
               
               
                 11 
                 LEPGVQSVEVDEPATE 
                 334 
                 0.82 
               
               
                 11 
                 HQQILDILTGKFDKLS 
                 261 
                 0.82 
               
               
                 12 
                 RGKIGKINIHQSGKIT 
                 364 
                 0.81 
               
               
                 13 
                 PKPEDNEEEDVQMVDD 
                 411 
                 0.80 
               
               
                 13 
                 SKEERAKVAPTIKQEP 
                 37 
                 0.80 
               
               
                 13 
                 HLPTYTQPPSAVKLEP 
                 321 
                 0.80 
               
               
                 13 
                 DKLSTKTEDSHQKQQT 
                 273 
                 0.80 
               
               
                 14 
                 DVELENDKTEINFDDQ 
                 297 
                 0.79 
               
               
                 14 
                 ENEIAMPDVEIKQEPN 
                 183 
                 0.79 
               
               
                 15 
                 DSTAGSTPMPISLTQS 
                 199 
                 0.76 
               
               
                 15 
                 TKINMTQKYRFNEEDT 
                 151 
                 0.76 
               
               
                 15 
                 SSSSSSGSKSAAKFKP 
                 15 
                 0.76 
               
               
                 15 
                 SDMIYNSNGDLSSSST 
                 106 
                 0.76 
               
               
                 16 
                 KTEINFDDQYVLFQLP 
                 304 
                 0.75 
               
               
                 16 
                 KSAAKFKPKVVQRKSK 
                 23 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 311 
                 346 
                 316 
                 DQYVLFQLPKHLPTYTQPPSAVKLEPGVQSVEVDEP 
               
               
                 166 
                 174 
                 170 
                 TVLFPVRPF 
               
               
                 432 
                 439 
                 438 
                 TGKVVRLG 
               
               
                 396 
                 408 
                 402 
                 TDFLQELALIEIN 
               
               
                 25 
                 36 
                 31 
                 AAKFKPKVVQRK 
               
               
                 88 
                 95 
                 89 
                 SAGAVSIG 
               
               
                 256 
                 270 
                 265 
                 KVISDHQQILDILTG 
               
               
                 42 
                 49 
                 45 
                 AKVAPTIK 
               
               
                 11 
                 17 
                 16 
                 RKPVSSS 
               
               
                 207 
                 212 
                 211 
                 MPISLT 
               
               
                 387 
                 393 
                 389 
                 RLNVTKG 
               
               
                 188 
                 194 
                 192 
                 MPDVEIK 
               
               
                   
               
            
           
           
               
               
            
               
                 17. IPF2140(CAF40) 
                   
               
               
                 MSSVGNPVHSLASTDSTASSSSSNKALNDEQIYQWISELVTGNNRERALLELGKKREQYDDLALVLWNSFGV 
               
               
                   
               
               
                 ITVLLEEIISVYPYLNPPNLSASISNRVCNALALLQCVASNVQTRTLFLNANLPLYLYPFLSTNARQRSFEY 
               
               
                   
               
               
                 LRLTSLGVIGALVKNDTPEVINFLLTTEIVPLCLNIMEISSELSKTVAIFILQKILLDDQGLAYVCTTFERF 
               
               
                   
               
               
                 HTVASVLSKMIDQLSIAVNSTNSQQQQQQQGQQAQQQQQQQQQTQSVPSSNSSGRLLKHVVRCYMRLSDNLE 
               
               
                   
               
               
                 ARKALANILPEPLRDGTFSTILQDDLATKRCLSQLLSNINEPQ* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 YQWISELVTGNNRERA 
                 33 
                 0.86 
               
               
                 2 
                 FGVITVLLEEIISVYP 
                 70 
                 0.85 
               
               
                 2 
                 LQKILLDDQGLAYVCT 
                 196 
                 0.85 
               
               
                 2 
                 MSSVGNPVHSLASTDS 
                 1 
                 0.85 
               
               
                 3 
                 TDSTASSSSSNKALND 
                 14 
                 0.84 
               
               
                 4 
                 MRLSDNLEARKALANI 
                 281 
                 0.82 
               
               
                 5 
                 QGLAYVCTTFERFHTV 
                 204 
                 0.81 
               
               
                 5 
                 LVKNDTPEVINFLLTT 
                 156 
                 0.81 
               
               
                 6 
                 FSTILQDDLATKRCLS 
                 306 
                 0.79 
               
               
                 7 
                 ANILPEPLRDGTFSTI 
                 294 
                 0.78 
               
               
                 7 
                 ASNVQTRTLFLNANLP 
                 111 
                 0.78 
               
               
                 8 
                 KKREQYDDLALVLWNS 
                 54 
                 0.77 
               
               
                 8 
                 LGVIGALVKNDTPEVI 
                 150 
                 0.77 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 97 
                 114 
                 107 
                 SNRVCNALALLQCVASNV 
               
               
                 162 
                 181 
                 175 
                 PEVINFLLTTEIVPLCLNIM 
               
               
                 270 
                 282 
                 276 
                 GRLLKHVVRCYMR 
               
               
                 116 
                 134 
                 130 
                 TRTLFLNANLPLYLYPFLS 
               
               
                 60 
                 95 
                 74 
                 DDLALVLWNSFGVITVLLEEIISVYPYLNPPNLSAS 
               
               
                 316 
                 326 
                 322 
                 TKRCLSQLLSN 
               
               
                 188 
                 213 
                 207 
                 SKTVAIFILQKILLDDQGLAYVCTTF 
               
               
                 216 
                 235 
                 220 
                 FHTVASVLSKMIDQLSIAVN 
               
               
                 142 
                 159 
                 155 
                 FEYLRLTSLGVIGALVKN 
               
               
                 5 
                 14 
                 10 
                 GNPVHSLAST 
               
               
                 290 
                 300 
                 295 
                 RKALANILPEP 
               
               
                 33 
                 40 
                 37 
                 YQWISELV 
               
               
                 307 
                 313 
                 312 
                 STILQDD 
               
               
                 260 
                 266 
                 261 
                 TQSVPSS 
               
               
                 247 
                 256 
                 251 
                 GQQAQQQQQQ 
               
               
                   
               
            
           
           
               
               
            
               
                 18. IPF19724(TBF1) 
                   
               
               
                 MSDQLEKDIEESIANLDYQQNQEHHETEQDKDKEHQDVEKQSSEEETKGIEHVTDSNIDVIEVTKSRDTEEV 
               
               
                   
               
               
                 IENSPVDPQLKEQQESTTKMSSSERDLVDEIDELFTNSTKIVTENNQPSETNKRAYESVETPQELTPNDKRQ 
               
               
                   
               
               
                 KLDANTETSVPTELESVNNHNEQSQPIEPTQERQPSTTETTYSISVPVSTTNEVERASSSINEQEDLEMIAK 
               
               
                   
               
               
                 QYQQATNLEIERAMEGHGDGGQHFSTQENGQPSGSSLISSIVPSDSELLNTNQAYAAYTSLSSQLEQHTSAS 
               
               
                   
               
               
                 AMLSSATLSALPLSIIAPVYLPPRIQLLINTLPTLDNLATQLLRTVATSPYQKIIDLASNPDTSAGATYRDL 
               
               
                   
               
               
                 TSLFEFTKRLYSEDDPFLTVEHIAPGMWKEGEETPSIFKPKQQSIESTLRKVNLATFLAATLGTMEIGFFYL 
               
               
                   
               
               
                 NESFLDVFCPSNNLDPSNALSNLGGYQNGLQSTDSPVGARVGKLLKPQATLYLDLKTQAYISAIEAGERSKE 
               
               
                   
               
               
                 EILEDILPDDLHVYLMSRRNAKLLSPTETDFVWRCKQRKESLLNYTEETPLSEQYDWFTFLRDLFDYVSKNI 
               
               
                   
               
               
                 AYLIWGKMGKTMKNRREDTPHTQELLDNTTGSTQMPNQLSSSSGQASSTPSVVDPNKMLVSEMREANIAVPK 
               
               
                   
               
               
                 PSQRRAWSREEEKALRHALELKGPHWATILELFGQGGKISEALKNRTQVQLKDKARNWKKFFLRSGLEIPSY 
               
               
                   
               
               
                 LRGVTGGVDDGKRKKDNVTKKTAAAPVPNMSEQLQQQQQRQQEKQEKQQQEEQQAQQSEPQQEPQQEPQQEQ 
               
               
                   
               
               
                 QQEQQQEQQQEQQQEQQQEQQQEQQQEQQQEQREETQQTEQEQPDQPQEEQQQEKEQPDQQQQEKEQPDQQQ 
               
               
                   
               
               
                 PDQQHPDRQQQEQIQQPENSDK* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 QQSIESTLRKVNLATF 
                 402 
                 0.92 
               
               
                 1 
                 HNEQSQPIEPTQERQP 
                 164 
                 0.92 
               
               
                 2 
                 EEQQQEKEQPDQQQQE 
                 841 
                 0.90 
               
               
                 2 
                 GVTGGVDDGKRKKDNV 
                 723 
                 0.90 
               
               
                 3 
                 GGKISEALKNRTQVQL 
                 684 
                 0.89 
               
               
                 3 
                 SEEETKGIEHVTDSNI 
                 43 
                 0.89 
               
               
                 3 
                 QLLINTLPTLDNLATQ 
                 314 
                 0.89 
               
               
                 3 
                 DQLEKDIEESIANLDY 
                 3 
                 0.89 
               
               
                 4 
                 NGLQSTDSPVGARVGK 
                 460 
                 0.88 
               
               
                 5 
                 DQQQQEKEQPDQQQPD 
                 851 
                 0.87 
               
               
                 5 
                 SSSGQASSTPSVVDPN 
                 617 
                 0.87 
               
               
                 5 
                 YRDLTSLFEFTKRLYS 
                 357 
                 0.87 
               
               
                 5 
                 TETTYSISVPVSTTNE 
                 182 
                 0.87 
               
               
                 5 
                 ETSVPTELESVNNHNE 
                 151 
                 0.87 
               
               
                 5 
                 TPQELTPNDKRQKLDA 
                 133 
                 0.87 
               
               
                 6 
                 ISAIEAGERSKEEILE 
                 493 
                 0.86 
               
               
                 7 
                 NRREDTPHTQELLDNT 
                 590 
                 0.85 
               
               
                 7 
                 SSLISSIVPSDSELLN 
                 251 
                 0.85 
               
               
                 7 
                 SINEQEDLEMIAKQYQ 
                 204 
                 0.85 
               
               
                 8 
                 QPDQQQPDQQHPDRQQ 
                 859 
                 0.84 
               
               
                 8 
                 QTEQEQPDQPQEEQQQ 
                 830 
                 0.84 
               
               
                 8 
                 TEEVIENSPVDPQLKE 
                 69 
                 0.84 
               
               
                 8 
                 TGSTQMPNQLSSSSGQ 
                 606 
                 0.84 
               
               
                 8 
                 NYTEETPLSEQYDWFT 
                 548 
                 0.84 
               
               
                 8 
                 EFTKRLYSEDDPFLTV 
                 365 
                 0.84 
               
               
                 8 
                 EGHGDGGQHFSTQENG 
                 231 
                 0.84 
               
               
                 9 
                 GLEIPSYLRGVTGGVD 
                 714 
                 0.83 
               
               
                 9 
                 KEEILEDILPDDLHVY 
                 503 
                 0.83 
               
               
                 9 
                 PGMWKEGEETPSIFKP 
                 385 
                 0.83 
               
               
                 9 
                 PLSIIAPVYLPPRIQL 
                 300 
                 0.83 
               
               
                 10 
                 LIWGKMGKTMKNRRED 
                 579 
                 0.82 
               
               
                 10 
                 TMEIGFFYLNESFLDV 
                 424 
                 0.82 
               
               
                 11 
                 GKRKKDNVTKKTAAAP 
                 731 
                 0.81 
               
               
                 11 
                 QRRAWSREEEKALRHA 
                 651 
                 0.81 
               
               
                 11 
                 DLHVYLMSRRNAKLLS 
                 514 
                 0.81 
               
               
                 11 
                 TVEHIAPGMWKEGEET 
                 379 
                 0.81 
               
               
                 11 
                 QEHHETEQDKDKEHQD 
                 22 
                 0.81 
               
               
                 12 
                 GARVGKLLKPQATLYL 
                 470 
                 0.80 
               
               
                 12 
                 DVEKQSSEEETKGIEH 
                 37 
                 0.80 
               
               
                 13 
                 STTKMSSSERDLVDEI 
                 88 
                 0.79 
               
               
                 13 
                 KKTAAAPVPNMSEQLQ 
                 740 
                 0.79 
               
               
                 13 
                 EVTKSRDTEEVIENSP 
                 62 
                 0.79 
               
               
                 13 
                 DFVWRCKQRKESLLNY 
                 534 
                 0.79 
               
               
                 13 
                 IEHVTDSNIDVIEVTK 
                 50 
                 0.79 
               
               
                 13 
                 QKIIDLASNPDTSAGA 
                 340 
                 0.79 
               
               
                 13 
                 KQYQQATNLEIERAME 
                 216 
                 0.79 
               
               
                 13 
                 TQERQPSTTETTYSIS 
                 174 
                 0.79 
               
               
                 14 
                 SEPQQEPQQEPQQEQQ 
                 778 
                 0.78 
               
               
                 14 
                 KMLVSEMREANIAVPK 
                 633 
                 0.78 
               
               
                 14 
                 VSKNIAYLIWGKMGKT 
                 572 
                 0.78 
               
               
                 15 
                 NSPVDPQLKEQQESTT 
                 75 
                 0.77 
               
               
                 15 
                 FSTQENGQPSGSSLIS 
                 240 
                 0.77 
               
               
                 16 
                 KLLSPTETDFVWRCKQ 
                 526 
                 0.76 
               
               
                 16 
                 TNEVERASSSINEQED 
                 195 
                 0.76 
               
               
                 17 
                 EQQAQQSEPQQEPQQE 
                 772 
                 0.75 
               
               
                 17 
                 DWFTFLRDLFDYVSKN 
                 560 
                 0.75 
               
               
                 17 
                 RTVATSPYQKIIDLAS 
                 332 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 288 
                 346 
                 306 
                 SAMLSSATLSALPLSIIAPVYLPPRIQLLINTLPT 
               
               
                   
                   
                   
                 LDNLATQLLRTVATSPYQKIIDLA 
               
               
                 186 
                 193 
                 189 
                 YSISVPVS 
               
               
                 428 
                 444 
                 439 
                 GFFYLNESFLDVFCPSN 
               
               
                 250 
                 263 
                 256 
                 GSSLISSIVPSDSE 
               
               
                 512 
                 520 
                 518 
                 PDDLHVYLM 
               
               
                 624 
                 638 
                 626 
                 STPSVVDPNKMLVSE 
               
               
                 465 
                 496 
                 484 
                 TDSPVGARVGKLLKPQATLYLDLKTQAYISAI 
               
               
                 377 
                 383 
                 380 
                 FLTVEHI 
               
               
                 709 
                 727 
                 718 
                 FFLRSGLEIPSYLRGVTGG 
               
               
                 409 
                 421 
                 415 
                 LRKVNLATFLAAT 
               
               
                 58 
                 64 
                 61 
                 IDVIEVT 
               
               
                 565 
                 581 
                 571 
                 LRDLFDYVSKNIAYLIW 
               
               
                 643 
                 649 
                 647 
                 NIAVPKP 
               
               
                 74 
                 81 
                 79 
                 ENSPVDPQ 
               
               
                 663 
                 670 
                 666 
                 LRHALELK 
               
               
                 270 
                 284 
                 274 
                 AYAAYTSLSSQLEQH 
               
               
                 743 
                 748 
                 745 
                 AAAPVP 
               
               
                 674 
                 681 
                 678 
                 WATILELF 
               
               
                 525 
                 530 
                 528 
                 AKLLSP 
               
               
                 360 
                 365 
                 363 
                 LTSLFE 
               
               
                 128 
                 134 
                 134 
                 YESVETP 
               
               
                 396 
                 403 
                 398 
                 SIFKPKQQ 
               
               
                 615 
                 621 
                 617 
                 LSSSSGQ 
               
               
                 35 
                 41 
                 38 
                 HQDVEKQ 
               
               
                   
               
            
           
           
               
               
            
               
                 19. IPF11711 
                   
               
               
                 MIVGKRDHHQRMEMAKPLRSLIDKLTTCDINELPQYLQENFKWQRPRGDLIHWIPLLNRFDEIFEQKIEKYG 
               
               
                   
               
               
                 LDKDNVKLSLVSPEDERLIVSCLQFTYILLDHCFDKQVYSSSERIYALINSSSLEIRLRALEVGIVLAEKFV 
               
               
                   
               
               
                 QTTSSRFSAPKPVRNKVLEIAKSFPPLVPIDSTLKQLAENKKNNNHRDTDEKPSIIGDHYNFVYTLDPEKKY 
               
               
                   
               
               
                 PSKWKSINYQYYKSVPNTPTLNKNASKSKSNDKKKEDTVTEGLHIFHLPEESVRKLTVQQLFEKGMEVLPPE 
               
               
                   
               
               
                 SWFCFGIHAQMTKSFNSTSSDAMQLREKLIQIKCLAVGFTCCMLSSQVTSTKLFETEPYIFSFLVEAISPEN 
               
               
                   
               
               
                 SSLVSRDVYFAAIRALECISFKKVWGAELIRTMGGNVSHGILFQCLRHIWKMVKDQKEDYFEEGYIHFFNLI 
               
               
                   
               
               
                 GNLISNKSLVPKLTAGGILDDLMPFLNLPTKYRWSCSAAVHLITMYLASAKDSLDEFVTNDGFTLLIGNIRR 
               
               
                   
               
               
                 EVDFALENPEFGGGAPKDAIVYYSITLRQANYIRNLMKLVADLIQSDSGDRLRNLFDSPLLESFNKVLTHPH 
               
               
                   
               
               
                 VFGPSILAATIDSVFFIIHNEPTAFSILNEAKVIDTILDNYESLFLPSGPLLQILPEVLGAICLNNEGLNKV 
               
               
                   
               
               
                 KDKKLIQVFFKSFYNLNNAKELVRTESSTNLGCSLDELGRHYTSLKPIILQQLSELIENMSEYVNQRLPGIE 
               
               
                   
               
               
                 FYTSDSGSLFSGKGDDSPVKVENGKEITSWENEDSAYLLDNVFNFLGGLLQDSGQWGTDVIQKISFKSWIKL 
               
               
                   
               
               
                 LTLRNAPWDYSMSNGIVSFMGILKYFDDEKREYGLPVIIEELDKTLKLDSVLSYIKYKGEVSYFETIEPQQA 
               
               
                   
               
               
                 TILLQDLNIINVLLYSLTEIYINLGSLFNERLGQIVSLFSNSNLLMNLVQLLERSIIEEAIIVSNTPDEVLK 
               
               
                   
               
               
                 MTHNFPNDSPPLQINVCDPSEIKADTKGTSAKFKNTLQLRTGSYYFRGYIPLILASVVRSCIPKRQDHAEGQ 
               
               
                   
               
               
                 ARQDAVEILLSLGKEFTDSIGRKFNNSYYEESFILNIAYVALYILNQKERSKDQVYTPFAISLFQNGFFKVA 
               
               
                   
               
               
                 EATCISLWNKLLIMDPELASATLDLKYISTQESSIIKNALGQILMIFAKTVNHENIPNVPFAKFYFYQGFES 
               
               
                   
               
               
                 NIEQSLTSALLLQIRSVALSLVEHTVGSKSQLTGTNKHPDNVPTPLIEQIAVIIKDIFVGKKELSDSEFIPF 
               
               
                   
               
               
                 DTRNISPPSDQFAYLISLGMSEDQAAHFFEHGCNLSDIASGKFLRCVEIDLKEEQWQSIAESIRDEKIDFSI 
               
               
                   
               
               
                 DFEKFKSTKDILKERKAVDFENIWMNIAQSFPKSISFISDFIMLVSYKEFYDEMLDYTPKIKWPIEDKELFG 
               
               
                   
               
               
                 INLYIIALLLQTGKPHIHRRDLMLNAQTLINPDIISTDTVNEKFFPSLLLVLERMMILLEEPEHEMAPELPF 
               
               
                   
               
               
                 TIQKKKEFDVATKEFKAKTFDLLVKLEVKDNLESAYGLARVLVLYARDKSYADRLAGSQILKDLLKLVRTNV 
               
               
                   
               
               
                 KRKTVIEALRTSVILIFRYCFETSRMAENIMNIEVTALFNNPIRQIKDLHACLRESAPLVFRDIDMAVGVIC 
               
               
                   
               
               
                 NNILLEGYTGEESYVSKIAIRKRKRDESMQDVEMSEPEASKPLLEFLTFSKKTQEEVKPRATALNFFIHQLI 
               
               
                   
               
               
                 PTHSLESSTGAEFERRCAISSIAKMCLLSLVSSTISGDNDSSKAKKEDADLALIRRFVVDLMMKILKDVSQS 
               
               
                   
               
               
                 NTLGSIKYGKLLDLFELSGSLISTKFRDSVGPLLNKQATQYDQFHISKIYIEKQVPNLLTNLIAEFDLNFPQ 
               
               
                   
               
               
                 IDKVVKAALKPMTFLGKNKVEYEELFAGDANQGDHNDDDDNLPEDVDYHEETPDLFRNSTLGMYDVESEGDD 
               
               
                   
               
               
                 EFYDAEDPVDAMMTGEDLSGASDDGDDDDDEDDDGDDDIDDMSSELSAIDSDLDGGDNADDIEMEIEVDPYD 
               
               
                   
               
               
                 DERGSEDIDEDASDMEDIEIIDDLDLVSQTDGDDDGDDDDGRDDEEDSSSWDDDEMSEYDEDELDGWIEQLD 
               
               
                   
               
               
                 DSEDSNDEVQSRRRPRDPFTSLNNDAESGLRQRLFLDGEADFDDDNAIESDGELSEMDSRSDFEVRMVTPSR 
               
               
                   
               
               
                 GRRRRILDRADFNELERASPALSVLLDGLFRDRNFGSIEISRYXHLXHDTSTIGRLXEXMMHXGRVSKHXNQ 
               
               
                   
               
               
                 DNKLHIKXTXERWSDVLKMYYPRDGGDLVYPLTTTIIGRIKDESQAIANRKKEEQEKAKKEREEKRRKQLEE 
               
               
                   
               
               
                 EEKRRQEESRQRQESTANVPEREPVMVRIGDRDVDISGTEIDRDYIEALPEDMREEVFASYVRERRANASST 
               
               
                   
               
               
                 DTDVREIDPDFLDALPDNIRTEILQQETMARRFANFESSSAQDEFEVDDAGEEDVFEDADDARPSGSGRSSS 
               
               
                   
               
               
                 AATTRAQKKPAGKVYFSPLVDKQGIAALIRLLFSPLTISQREHIYHALQYMCYNKQSRIEIMSLMIAILNDC 
               
               
                   
               
               
                 FTNNRPAQKVYTQVCNKAGGNKDSKQQYKLPVGATQISVGIQIVEAVDYLLERNNHLKYFLLTEHENTFILR 
               
               
                   
               
               
                 KDKKSASKESKFPINYMLKILDNKLVTDDQTLLDILARVFQVASRALHALKNSANADDKDDDKENEKEKEKD 
               
               
                   
               
               
                 KPHAPPPPVIPDSNYRLIIKILTGNDCSNTTFRRTISAMQNFSVLPNAQKLFSLELSDKASELGQTIITDLN 
               
               
                   
               
               
                 NLTKELVAGGGSDSKSFSKFSAHWSDQAKLLRILTALDYMFENKEKNKEKGKEDEIEELTDLYKKLALGSLW 
               
               
                   
               
               
                 DALSETLRVLEEKPQLHNIANALLPLIEALMVVCKHSKVRELPIKDILKYEAKKIDFTKEPIESLFFSFTDE 
               
               
                   
               
               
                 HKKILNQMVRSNPNLMSGPFGMLVRNPRVLEFDNKKNYFDRKLHQDKKENRKMLVSVRRDQVFLDSYRSLFF 
               
               
                   
               
               
                 KPKDEFRNSKLEINFKGEQGIDAGGVTREWYQVLSRQMFNPDYALFTPVVSDETTFHPNRTSYINPEHLSFF 
               
               
                   
               
               
                 KFIGRIIGKAIYDNCFLDCHFSRAVYKRILGKPQSLKDMETLDLEYFKSLMWMLENDITDVITEDFSVETDD 
               
               
                   
               
               
                 YGEHKIIDLIPNGRNIPVTEENKNEYVKKVVEYRLQTSVEEQMENFLIGFHEIIPKDLVAIFDEKELELLIS 
               
               
                   
               
               
                 GLPDIDVSDWQNHTSYNNYSPSSLQIQWFWRAVKSFDNEERARLLQFATGTSKVPLNGFKELSGASGTCKFS 
               
               
                   
               
               
                 IHRDYGSTDRLPSSHTCFNQIDLPAYDCYETLRGSLLMAITEGHEGFGLA* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 PFTIQKKKEFDVATKE 
                 1439 
                 0.97 
               
               
                 2 
                 LSAIDSDLDGGDNADD 
                 1918 
                 0.96 
               
               
                 3 
                 PSIIGDHYNFVYTLDP 
                 197 
                 0.95 
               
               
                 4 
                 SGASDDGDDDDDEDDD 
                 1891 
                 0.94 
               
               
                 5 
                 VSDWQNHTSYNNYSPS 
                 3103 
                 0.93 
               
               
                 5 
                 ADDIEMEIEVDPYDDE 
                 1931 
                 0.93 
               
               
                 5 
                 MSEDQAAHFFEHGCNL 
                 1244 
                 0.93 
               
               
                 6 
                 TPVVSDETTFHPNRTS 
                 2927 
                 0.92 
               
               
                 6 
                 VESEGDDEFYDAEDPV 
                 1866 
                 0.92 
               
               
                 6 
                 SQLTGTNKHPDNVPTP 
                 1182 
                 0.92 
               
               
                 7 
                 EIKADTKGTSAKFKNT 
                 957 
                 0.91 
               
               
                 7 
                 EEAIIVSNTPDEVLKM 
                 922 
                 0.91 
               
               
                 7 
                 DRLPSSHTCFNQIDLP 
                 3177 
                 0.91 
               
               
                 7 
                 QSRIEIMSLMIAILND 
                 2432 
                 0.91 
               
               
                 7 
                 DVREIDPDFLDALPDN 
                 2307 
                 0.91 
               
               
                 7 
                 EVFASYVRERRANASS 
                 2288 
                 0.91 
               
               
                 7 
                 KWPIEDKELFGINLYI 
                 1358 
                 0.91 
               
               
                 8 
                 PEVLGAICLNNEGLNK 
                 632 
                 0.90 
               
               
                 8 
                 PVTEENKNEYVKKVVE 
                 3041 
                 0.90 
               
               
                 8 
                 REHIYHALQYMCYNKQ 
                 2417 
                 0.90 
               
               
                 8 
                 NSTLGMYDVESEGDDE 
                 1858 
                 0.90 
               
               
                 8 
                 SSTISGDNDSSKAKKE 
                 1688 
                 0.90 
               
               
                 8 
                 DEKIDFSIDFEKFKST 
                 1289 
                 0.90 
               
               
                 8 
                 AVIIKDIFVGKKELSD 
                 1203 
                 0.90 
               
               
                 9 
                 SGKGDDSPVKVENGKE 
                 731 
                 0.89 
               
               
                 9 
                 SGTCKFSIHRDYGSTD 
                 3162 
                 0.89 
               
               
                 9 
                 HKIIDLIPNGRNIPVT 
                 3028 
                 0.89 
               
               
                 9 
                 VTREWYQVLSRQMFNP 
                 2906 
                 0.89 
               
               
                 9 
                 SGRSSSAATTRAQKKP 
                 2371 
                 0.89 
               
               
                 9 
                 DPEKKYPSKWKSINYQ 
                 211 
                 0.89 
               
               
                 9 
                 NDEVQSRRRPRDPFTS 
                 2022 
                 0.89 
               
               
                 9 
                 DSSSWDDDEMSEYDED 
                 1991 
                 0.89 
               
               
                 9 
                 TDGDDDGDDDDGRDDE 
                 1974 
                 0.89 
               
               
                 9 
                 PVDAMMTGEDLSGASD 
                 1880 
                 0.89 
               
               
                 9 
                 KVEYEELFAGDANQGD 
                 1819 
                 0.89 
               
               
                 9 
                 ETSRMAENIMNIEVTA 
                 1534 
                 0.89 
               
               
                 9 
                 KLLIMDPELASATLDL 
                 1090 
                 0.89 
               
               
                 10 
                 YRLIIKILTGNDCSNT 
                 2607 
                 0.88 
               
               
                 10 
                 MVRIGDRDVDISGTEI 
                 2258 
                 0.88 
               
               
                 10 
                 QEESRQRQESTANVPE 
                 2238 
                 0.88 
               
               
                 10 
                 LXEXMMHXGRVSKHXN 
                 2144 
                 0.88 
               
               
                 10 
                 FGSIEISRYXHLXHDT 
                 2123 
                 0.88 
               
               
                 11 
                 EIYINLGSLFNERLGQ 
                 883 
                 0.87 
               
               
                 11 
                 VHLITMYLASAKDSLD 
                 472 
                 0.87 
               
               
                 11 
                 AGGILDDLMPFLNLPT 
                 447 
                 0.87 
               
               
                 11 
                 GRIIGKAIYDNCFLDC 
                 2956 
                 0.87 
               
               
                 11 
                 SELGQTIITDLNNLTK 
                 2653 
                 0.87 
               
               
                 11 
                 AQKVYTQVCNKAGGNK 
                 2455 
                 0.87 
               
               
                 11 
                 RSLIDKLTTCDINELP 
                 19 
                 0.87 
               
               
                 12 
                 IPKRQDHAEGQARQDA 
                 998 
                 0.86 
               
               
                 12 
                 GGLLQDSGQWGTDVIQ 
                 767 
                 0.86 
               
               
                 12 
                 RLPGIEFYTSDSGSLF 
                 715 
                 0.86 
               
               
                 12 
                 SELIENMSEYVNQRLP 
                 702 
                 0.86 
               
               
                 12 
                 RKLHQDKKENRKMLVS 
                 2849 
                 0.86 
               
               
                 12 
                 TIIGRIKDESQAIANR 
                 2195 
                 0.86 
               
               
                 12 
                 DERGSEDIDEDASDME 
                 1945 
                 0.86 
               
               
                 12 
                 DANQGDHNDDDDNLPE 
                 1829 
                 0.86 
               
               
                 12 
                 PEHEMAPELPFTIQKK 
                 1430 
                 0.86 
               
               
                 12 
                 HAEGQARQDAVEILLS 
                 1004 
                 0.86 
               
               
                 13 
                 ENDITDVITEDFSVET 
                 3007 
                 0.85 
               
               
                 13 
                 LLRILTALDYMFENKE 
                 2694 
                 0.85 
               
               
                 13 
                 HALKNSANADDKDDDK 
                 2568 
                 0.85 
               
               
                 13 
                 YKSVPNTPTLNKNASK 
                 228 
                 0.85 
               
               
                 13 
                 WKSINYQYYKSVPNTP 
                 220 
                 0.85 
               
               
                 13 
                 VLKMYYPRDGGDLVYP 
                 2176 
                 0.85 
               
               
                 13 
                 SRGRRRRILDRADFNE 
                 2087 
                 0.85 
               
               
                 13 
                 PKPVRNKVLEIAKSFP 
                 154 
                 0.85 
               
               
                 14 
                 NFPNDSPPLQINVCDP 
                 940 
                 0.84 
               
               
                 14 
                 LPVIIEELDKTLKLDS 
                 827 
                 0.84 
               
               
                 14 
                 AKVIDTILDNYESLFL 
                 607 
                 0.84 
               
               
                 14 
                 VGKRDHHQRMEMAKPL 
                 3 
                 0.84 
               
               
                 14 
                 GIHAQMTKSFNSTSSD 
                 294 
                 0.84 
               
               
                 14 
                 VLSRQMFNPDYALFTP 
                 2913 
                 0.84 
               
               
                 14 
                 EFEVDDAGEEDVFEDA 
                 2348 
                 0.84 
               
               
                 14 
                 LSEMDSRSDFEVRMVT 
                 2070 
                 0.84 
               
               
                 14 
                 IESDGELSEMDSRSDF 
                 2064 
                 0.84 
               
               
                 14 
                 DEFYDAEDPVDAMMTG 
                 1872 
                 0.84 
               
               
                 14 
                 YHEETPDLFRNSTLGM 
                 1848 
                 0.84 
               
               
                 14 
                 TFSKKTQEEVKPRATA 
                 1632 
                 0.84 
               
               
                 14 
                 NPDIISTDTVNEKFFP 
                 1399 
                 0.84 
               
               
                 14 
                 TRNISPPSDQFAYLIS 
                 1226 
                 0.84 
               
               
                 15 
                 LQLRTGSYYFRGYIPL 
                 973 
                 0.83 
               
               
                 15 
                 SNTPDEVLKMTHNFPN 
                 928 
                 0.83 
               
               
                 15 
                 ERLIVSCLQFTYILLD 
                 88 
                 0.83 
               
               
                 15 
                 FFIIHNEPTAFSILNE 
                 591 
                 0.83 
               
               
                 15 
                 SVETDDYGEHKIIDLI 
                 3019 
                 0.83 
               
               
                 15 
                 MSGPFGMLVRNPRVLE 
                 2824 
                 0.83 
               
               
                 15 
                 EKEKDKPHAPPPPVIP 
                 2588 
                 0.83 
               
               
                 15 
                 KLHIKXTXERWSDVLK 
                 2163 
                 0.83 
               
               
                 15 
                 TSTIGRLXEXMMHXGR 
                 2138 
                 0.83 
               
               
                 15 
                 LVPIDSTLKQLAENKK 
                 171 
                 0.83 
               
               
                 15 
                 SLESSTGAEFERRCAI 
                 1660 
                 0.83 
               
               
                 15 
                 HQLIPTHSLESSTGAE 
                 1653 
                 0.83 
               
               
                 15 
                 KFVQTTSSRFSAPKPV 
                 142 
                 0.83 
               
               
                 15 
                 LVSYKEFYDEMLDYTP 
                 1340 
                 0.83 
               
               
                 15 
                 LGKEFTDSIGRKFNNS 
                 1020 
                 0.83 
               
               
                 16 
                 KEITSWENEDSAYLLD 
                 745 
                 0.82 
               
               
                 16 
                 FYTSDSGSLFSGKGDD 
                 721 
                 0.82 
               
               
                 16 
                 GCSLDELGRHYTSLKP 
                 680 
                 0.82 
               
               
                 16 
                 HWSDQAKLLRILTALD 
                 2687 
                 0.82 
               
               
                 16 
                 EEEKRRQEESRQRQES 
                 2232 
                 0.82 
               
               
                 16 
                 KEEQEKAKKEREEKRR 
                 2212 
                 0.82 
               
               
                 16 
                 RRRPRDPFTSLNNDAE 
                 2028 
                 0.82 
               
               
                 16 
                 KQLAENKKNNNHRDTD 
                 179 
                 0.82 
               
               
                 16 
                 KPRATALNFFIHQLIP 
                 1642 
                 0.82 
               
               
                 17 
                 PLLQILPEVLGAICLN 
                 626 
                 0.81 
               
               
                 17 
                 GGAPKDAIVYYSITLR 
                 517 
                 0.81 
               
               
                 17 
                 MPFLNLPTKYRWSCSA 
                 455 
                 0.81 
               
               
                 17 
                 QRPRGDLIHWIPLLNR 
                 44 
                 0.81 
               
               
                 17 
                 CCMLSSQVTSTKLFET 
                 329 
                 0.81 
               
               
                 17 
                 NELPQYLQENFKWQRP 
                 31 
                 0.81 
               
               
                 17 
                 FKSLMWMLENDITDVI 
                 2999 
                 0.81 
               
               
                 17 
                 YKRILGKPQSLKDMET 
                 2978 
                 0.81 
               
               
                 17 
                 LVRNPRVLEFDNKKNY 
                 2831 
                 0.81 
               
               
                 17 
                 ELPIKDILKYEAKKID 
                 2777 
                 0.81 
               
               
                 17 
                 RRTISAMQNFSVLPNA 
                 2625 
                 0.81 
               
               
                 17 
                 TTRAQKKPAGKVYFSP 
                 2379 
                 0.81 
               
               
                 17 
                 LQQETMARRFANFESS 
                 2328 
                 0.81 
               
               
                 17 
                 SKIAIRKRKRDESMQD 
                 1600 
                 0.81 
               
               
                 17 
                 ALLLQTGKPHIHRRDI 
                 1375 
                 0.81 
               
               
                 17 
                 RKFNNSYYEESFILNI 
                 1030 
                 0.81 
               
               
                 18 
                 IGNIRREVDFALENPE 
                 499 
                 0.80 
               
               
                 18 
                 ASAKDSLDEFVTNDGF 
                 480 
                 0.80 
               
               
                 18 
                 LRHIWKMVKDQKEDYF 
                 406 
                 0.80 
               
               
                 18 
                 LECISFKKVWGAELIR 
                 376 
                 0.80 
               
               
                 18 
                 DSKQQYKLPVGATQIS 
                 2471 
                 0.80 
               
               
                 18 
                 SPLTISQREHIYHALQ 
                 2410 
                 0.80 
               
               
                 18 
                 GWIEQLDDSEDSNDEV 
                 2010 
                 0.80 
               
               
                 18 
                 SKIYIEKQVPNLLTNL 
                 1775 
                 0.80 
               
               
                 18 
                 DESMQDVEMSEPEASK 
                 1610 
                 0.80 
               
               
                 18 
                 CLRESAPLVFRDIDMA 
                 1564 
                 0.80 
               
               
                 18 
                 MILLEEPEHEMAPELP 
                 1424 
                 0.80 
               
               
                 18 
                 GKKELSDSEFIPFDTR 
                 1212 
                 0.80 
               
               
                 19 
                 KKLIQVFFKSFYNLNN 
                 651 
                 0.79 
               
               
                 19 
                 HGILFQCLRHIWKMVK 
                 399 
                 0.79 
               
               
                 19 
                 RAVKSFDNEERARLLQ 
                 3127 
                 0.79 
               
               
                 19 
                 HEIIPKDLVAIFDEKE 
                 3075 
                 0.79 
               
               
                 19 
                 AGKVYFSPLVDKQGIA 
                 2387 
                 0.79 
               
               
                 19 
                 MSEYDEDELDGWIEQL 
                 2000 
                 0.79 
               
               
                 19 
                 EVDPYDDERGSEDIDE 
                 1939 
                 0.79 
               
               
                 19 
                 HNDDDDNLPEDVDYHE 
                 1835 
                 0.79 
               
               
                 19 
                 SGSLISTKFRDSVGPL 
                 1746 
                 0.79 
               
               
                 19 
                 KSTKDILKERKAVDFE 
                 1302 
                 0.79 
               
               
                 19 
                 ESNIEQSLTSALLLQI 
                 1151 
                 0.79 
               
               
                 19 
                 DLKYISTQESSIIKNA 
                 1104 
                 0.79 
               
               
                 19 
                 KQVYSSSERIYALINS 
                 108 
                 0.79 
               
               
                 20 
                 LGRHYTSLKPIILQQL 
                 686 
                 0.78 
               
               
                 20 
                 EQKIEKYGLDKDNVKL 
                 65 
                 0.78 
               
               
                 20 
                 YFEEGYIHFFNLIGNL 
                 420 
                 0.78 
               
               
                 20 
                 YRSLFFKPKDEFRNSK 
                 2875 
                 0.78 
               
               
                 20 
                 FEKGMEVLPPESWFCF 
                 278 
                 0.78 
               
               
                 20 
                 AGGGSDSKSFSKFSAH 
                 2672 
                 0.78 
               
               
                 20 
                 IVEAVDYLLERNNHLK 
                 2491 
                 0.78 
               
               
                 20 
                 DARPSGSGRSSSAATT 
                 2365 
                 0.78 
               
               
                 20 
                 SKPLLEFLTFSKKTQE 
                 1624 
                 0.78 
               
               
                 21 
                 GILKYFDDEKREYGLP 
                 813 
                 0.77 
               
               
                 21 
                 CFNQIDLPAYDCYETL 
                 3185 
                 0.77 
               
               
                 21 
                 TGTSKVPLNGFKELSG 
                 3145 
                 0.77 
               
               
                 21 
                 SGLPDIDVSDWQNHTS 
                 3096 
                 0.77 
               
               
                 21 
                 DMETLDLEYFKSLMWM 
                 2990 
                 0.77 
               
               
                 21 
                 LRVLEEKPQLHNIANA 
                 2743 
                 0.77 
               
               
                 21 
                 ANASSTDTDVREIDPD 
                 2299 
                 0.77 
               
               
                 21 
                 DKVVKAALKPMTFLGK 
                 1802 
                 0.77 
               
               
                 21 
                 KQATQYDQFHISKIYI 
                 1764 
                 0.77 
               
               
                 22 
                 FKSWIKLLTLRNAPWD 
                 786 
                 0.76 
               
               
                 22 
                 RDYGSTDRLPSSHTCF 
                 3171 
                 0.76 
               
               
                 22 
                 PINYMLKILDNKLVTD 
                 2533 
                 0.76 
               
               
                 22 
                 KPHIHRRDIMLNAQTL 
                 1382 
                 0.76 
               
               
                 22 
                 RKAVDFENIWMNIAQS 
                 1311 
                 0.76 
               
               
                 22 
                 PELASATLDLKYISTQ 
                 1096 
                 0.76 
               
               
                 22 
                 QRMEMAKPLRSLIDKL 
                 10 
                 0.76 
               
               
                 23 
                 PVKVENGKEITSWENE 
                 738 
                 0.75 
               
               
                 23 
                 VDFALENPEFGGGAPK 
                 506 
                 0.75 
               
               
                 23 
                 RLLQFATGTSKVPLNG 
                 3139 
                 0.75 
               
               
                 23 
                 YSPSSLQIQWFWRAVK 
                 3115 
                 0.75 
               
               
                 23 
                 PPESWFCFGIHAQMTK 
                 286 
                 0.75 
               
               
                 23 
                 CSNTTFRRTISAMQNF 
                 2619 
                 0.75 
               
               
                 23 
                 PHAPPPPVIPDSNYRL 
                 2594 
                 0.75 
               
               
                 23 
                 DYIEALPEDMREEVFA 
                 2276 
                 0.75 
               
               
                 23 
                 XGRVSKHXNQDNKLHI 
                 2151 
                 0.75 
               
               
                 23 
                 DFDDDNAIESDGELSE 
                 2057 
                 0.75 
               
               
                 23 
                 TNLIAEFDLNFPQIDK 
                 1788 
                 0.75 
               
               
                 23 
                 EFERRCAISSIAKMCL 
                 1668 
                 0.75 
               
               
                 23 
                 AGSQILKDLLKLVRTN 
                 1496 
                 0.75 
               
               
                 23 
                 VLYARDKSYADRLAGS 
                 1483 
                 0.75 
               
               
                 23 
                 KEFDVATKEFKAKTFD 
                 1446 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 1670 
                 1690 
                 1685 
                 ERRCAISSIAKMCLLSLVSST 
               
               
                 975 
                 1001 
                 991 
                 LRTGSYYFRGYIPLILASVVRSCIPKR 
               
               
                 89 
                 147 
                 93 
                 RLIVSCLQFTYILLDHCFDKQVYSSSERIYALINSSSLEIR 
               
               
                   
                   
                   
                 LRALEVGIVLAEKFVQTT 
               
               
                 1413 
                 1429 
                 1417 
                 FPSLLLVLERMMILLEE 
               
               
                 1475 
                 1488 
                 1481 
                 AYGLARVLVLYARD 
               
               
                 1042 
                 1054 
                 1050 
                 ILNIAYVALYILN 
               
               
                 616 
                 642 
                 637 
                 NYESLFLPSGPLLQILPEVLGAICLNN 
               
               
                 1157 
                 1183 
                 1171 
                 SLTSALLLQIRSVALSLVEHTVGSKSQ 
               
               
                 2387 
                 2399 
                 2393 
                 AGKVYFSPLVDKQ 
               
               
                 1459 
                 1467 
                 1465 
                 TFDLLVKLE 
               
               
                 465 
                 484 
                 471 
                 RWSCSAAVHLITMYLASAKD 
               
               
                 2752 
                 2778 
                 2769 
                 LHNIANALLPLIEALMVVCKHSKVREL 
               
               
                 1368 
                 1387 
                 1374 
                 GINLYIIALLLQTGKPHIHR 
               
               
                 2106 
                 2117 
                 2111 
                 ASPALSVLLDGL 
               
               
                 2964 
                 2987 
                 2970 
                 YDNCFLDCHFSRAVYKRILGKPQS 
               
               
                 76 
                 85 
                 81 
                 DNVKLSLVSP 
               
               
                 873 
                 891 
                 879 
                 IINVLLYSLTEIYINLGSL 
               
               
                 315 
                 339 
                 322 
                 EKLIQIKCLAVGFTCCMLSSQVTST 
               
               
                 561 
                 596 
                 574 
                 DSPLLESFNKVLTHPHVFGPSILAATIDSVFFIIHN 
               
               
                 2455 
                 2465 
                 2460 
                 AQKVYTQVCNK 
               
               
                 1011 
                 1021 
                 1017 
                 QDAVEILLSLG 
               
               
                 2922 
                 2933 
                 2927 
                 DYALFTPVVSDE 
               
               
                 344 
                 356 
                 350 
                 TEPYIFSFLVEAI 
               
               
                 1577 
                 1587 
                 1581 
                 DMAVGVICNNI 
               
               
                 1514 
                 1534 
                 1529 
                 RKTVIEALRTSVILIFRYCFE 
               
               
                 521 
                 534 
                 526 
                 KDAIVYYSITLRQA 
               
               
                 151 
                 181 
                 171 
                 FSAPKPVRNKVLEIAKSFPPLVPIDSTLKQL 
               
               
                 2547 
                 2571 
                 2559 
                 TDDQTLLDILARVFQVASRALHALK 
               
               
                 945 
                 956 
                 950 
                 SPPLQINVCDPS 
               
               
                 837 
                 858 
                 846 
                 TLKLDSVLSYIKYKGEVSYFET 
               
               
                 398 
                 411 
                 403 
                 SHGILFQCLRHIWK 
               
               
                 2505 
                 2511 
                 2507 
                 LKYFLLT 
               
               
                 825 
                 833 
                 828 
                 YGLPVIIEE 
               
               
                 3051 
                 3063 
                 3052 
                 VKKVVEYRLQTSV 
               
               
                 256 
                 267 
                 262 
                 TEGLHIFHLPEE 
               
               
                 1265 
                 1274 
                 1270 
                 GKFLRCVEID 
               
               
                 1706 
                 1720 
                 1712 
                 DLALIRRFVVDLMMK 
               
               
                 1801 
                 1812 
                 1807 
                 IDKVVKAALKPM 
               
               
                 2475 
                 2499 
                 2492 
                 QYKLPVGATQISVGIQIVEAVDYLL 
               
               
                 540 
                 550 
                 546 
                 LMKLVADLIQS 
               
               
                 1232 
                 1242 
                 1239 
                 PSDQFAYLISL 
               
               
                 3180 
                 3199 
                 3194 
                 PSSHTCFNQIDLPAYDCYET 
               
               
                 2289 
                 2296 
                 2292 
                 VFASYVRE 
               
               
                 897 
                 903 
                 899 
                 GQIVSLF 
               
               
                 2401 
                 2415 
                 2406 
                 IAALIRLLFSPLTIS 
               
               
                 361 
                 384 
                 366 
                 SSLVSRDVYFAAIRALECISFKKV 
               
               
                 2187 
                 2195 
                 2191 
                 DLVYPLTTT 
               
               
                 269 
                 278 
                 275 
                 VRKLTVQQLF 
               
               
                 650 
                 661 
                 655 
                 DKKLIQVFFKSF 
               
               
                 2417 
                 2431 
                 2423 
                 REHIYHALQYMCYNK 
               
               
                 688 
                 704 
                 698 
                 RHYTSLKPIILQQLSEL 
               
               
                 1557 
                 1575 
                 1562 
                 QIKDLHACLRESAPLVFRD 
               
               
                 1325 
                 1345 
                 1340 
                 QSFPKSISFISDFIMLVSYKE 
               
               
                 909 
                 919 
                 915 
                 LMNLVQLLERS 
               
               
                 1192 
                 1214 
                 1201 
                 DNVPTPLIEQIAVIIKDIFVGKK 
               
               
                 49 
                 58 
                 53 
                 DLIHWIPLLN 
               
               
                 1497 
                 1511 
                 1505 
                 GSQILKDLLKLVRTN 
               
               
                 1642 
                 1662 
                 1653 
                 KPRATALNFFIHQLIPTHSLE 
               
               
                 2594 
                 2604 
                 2599 
                 PHAPPPPVIPD 
               
               
                 1596 
                 1603 
                 1601 
                 ESYVSKIA 
               
               
                 3091 
                 3104 
                 3096 
                 LELLISGLPDIDVS 
               
               
                 438 
                 445 
                 444 
                 NKSLVPKL 
               
               
                 2723 
                 2738 
                 2729 
                 LTDLYKKLALGSLWDA 
               
               
                 1076 
                 1096 
                 1082 
                 FFKVAEATCISLWNKLLIMDP 
               
               
                 1061 
                 1074 
                 1066 
                 DQVYTPFAISLFQN 
               
               
                 224 
                 234 
                 228 
                 NYQYYKSVPNT 
               
               
                 1736 
                 1752 
                 1742 
                 YGKLLDLFELSGSLIST 
               
               
                 3071 
                 3086 
                 3080 
                 LIGFHEIIPKDLVAIF 
               
               
                 2606 
                 2614 
                 2612 
                 NYRLIIKIL 
               
               
                 283 
                 296 
                 294 
                 EVLPPESWFCFGIH 
               
               
                 1136 
                 1149 
                 1142 
                 IPNVPFAKFYFYQG 
               
               
                 2861 
                 2881 
                 2872 
                 MLVSVRRDQVFLDSYRSLFFK 
               
               
                 756 
                 772 
                 760 
                 AYLLDNVFNFLGGLLQD 
               
               
                 2174 
                 2180 
                 2179 
                 SDVLKMY 
               
               
                 2691 
                 2703 
                 2695 
                 QAKLLRILTALDY 
               
               
                 778 
                 796 
                 783 
                 TDVIQKISFKSWIKLLTLR 
               
               
                 197 
                 211 
                 207 
                 PSIIGDHYNFVYTLD 
               
               
                 2633 
                 2649 
                 2646 
                 NFSVLPNAQKLFSLELS 
               
               
                 2909 
                 2916 
                 2914 
                 EWYQVLSR 
               
               
                 2437 
                 2448 
                 2442 
                 IMSLMIAILNDC 
               
               
                 1755 
                 1764 
                 1759 
                 RDSVGPLLNK 
               
               
                 1624 
                 1634 
                 1630 
                 SKPLLEFLTFS 
               
               
                 861 
                 871 
                 868 
                 PQQATILLQDL 
               
               
                 1965 
                 1973 
                 1971 
                 IDDLDLVSQ 
               
               
                 1768 
                 1794 
                 1784 
                 QYDQFHISKIYIEKQVPNLLTNLIAEF 
               
               
                 2780 
                 2788 
                 2781 
                 IKDILKYEA 
               
               
                 600 
                 612 
                 611 
                 AFSILNEAKVIDT 
               
               
                 2668 
                 2673 
                 2669 
                 KELVAG 
               
               
                 423 
                 434 
                 428 
                 EGYIHFFNLIGN 
               
               
                 1098 
                 1110 
                 1106 
                 LASATLDLKYIST 
               
               
                 2945 
                 2958 
                 2952 
                 NPEHLSFFKFIGRI 
               
               
                 3162 
                 3172 
                 3167 
                 SGTCKFSIHRD 
               
               
                 3138 
                 3144 
                 3141 
                 ARLLQFA 
               
               
                 2533 
                 2544 
                 2543 
                 PINYMLKILDNK 
               
               
                 33 
                 39 
                 35 
                 LPQYLQE 
               
               
                 922 
                 929 
                 924 
                 EEAIIVSN 
               
               
                 2829 
                 2840 
                 2834 
                 GMLVRNPRVLEF 
               
               
                 2047 
                 2053 
                 2049 
                 RQRLFLD 
               
               
                 806 
                 818 
                 812 
                 NGIVSFMGILKYF 
               
               
                 1116 
                 1131 
                 1125 
                 IKNALGQILMIFAKTV 
               
               
                 2995 
                 3001 
                 2999 
                 DLEYFKS 
               
               
                 1249 
                 1262 
                 1260 
                 AAHFFEHGCNLSDI 
               
               
                 17 
                 28 
                 19 
                 PLRSLIDKLTTC 
               
               
                 2740 
                 2750 
                 2742 
                 SETLRVLEEKP 
               
               
                 3117 
                 3123 
                 3118 
                 PSSLQIQ 
               
               
                 711 
                 722 
                 714 
                 YVNQRLPGIEFY 
               
               
                 678 
                 684 
                 682 
                 NLGCSLD 
               
               
                 2798 
                 2804 
                 2800 
                 IESLFFS 
               
               
                 451 
                 461 
                 457 
                 LDDLMPFLNLP 
               
               
                 3201 
                 3207 
                 3206 
                 RGSLLMA 
               
               
                 2313 
                 2321 
                 2316 
                 PDFLDALPD 
               
               
                 1843 
                 1849 
                 1845 
                 PEDVDYH 
               
               
                 3147 
                 3153 
                 3149 
                 TSKVPLN 
               
               
                 1437 
                 1442 
                 1441 
                 ELPFTI 
               
               
                 495 
                 500 
                 497 
                 FTLLIG 
               
               
                 1917 
                 1923 
                 1918 
                 ELSAIDS 
               
               
                 2681 
                 2687 
                 2684 
                 FSKFSAH 
               
               
                 668 
                 673 
                 673 
                 KELVRT 
               
               
                 932 
                 937 
                 936 
                 DEVLKM 
               
               
                 3126 
                 3131 
                 3128 
                 WRAVKS 
               
               
                 1219 
                 1224 
                 1219 
                 SEFIPF 
               
               
                 1448 
                 1453 
                 1453 
                 FDVATK 
               
               
                   
               
            
           
           
               
               
            
               
                 20. IPF1009 
                   
               
               
                 MSNNPHRTHKRQKSSVSNPGYYFTPETKSEIQQQQPQQQESQQQQQQQQQQHSQTHNIYDNDNYMNYNFPPT 
               
               
                   
               
               
                 SNRPRASTTTGTTSTTHPGSELSHESHSVHTSPLKRTASSELDQPIPAMAPSSPLVSSAPYYYQQPSQQQNL 
               
               
                   
               
               
                 SYHDHHHQQQQQQSTPQGQQLSQQTQSNSQSGVPPPLYGTSSSIPPGSTMQPSTSFAFHTSHSTYNPSFDSS 
               
               
                   
               
               
                 NLYNSAFRLPEYPTTSSSSLLSTTGGKQFQQSSALLPSGTLPPSILGTSSSSHVSALRQHQKNNLSISSHLT 
               
               
                   
               
               
                 LFSLSGNNSSQLQSQGSSFQQSETGVDDTKRSSKESTTIFNDLLFHLTSVDGSNINTFLLSILRKINSPFTL 
               
               
                   
               
               
                 DDFYNLLYNDRQRTLLDNSNYQNRIDKTIVSPSDTDMTVSIINQLLNFFKTPSMLVDYFPNMEDKDNKLANI 
               
               
                   
               
               
                 NYHELLRTFLAIKILHDILIQLPISEDDDPQNYTIPRLSIYKTYYIICQKLIASYPSASNTRNEQQKLILGQ 
               
               
                   
               
               
                 SKLGKLIKLVYPNLLIKRLGSRGESKYNYLGVMWNANIVQEEIKQLCDEHELNDLNEIFNSDNNNPFASIAP 
               
               
                   
               
               
                 SGSATTGSTPRRGLSHKRTSSKQKIKTEPVAGNPFLQPLQTSHHHHHSHHHHHEEQSQEESLSQQMGEHITA 
               
               
                   
               
               
                 PRLSFLRANSKYPTDVNLSVLDDDNWFVRLSYECYARQPALNRDLIQQIFLKNEFLLNNSSLLRNLMDSIIK 
               
               
                   
               
               
                 PLVMQETYSNVDLVLYLAILLEILPYLLLVKSSTNINLLKNLRLNLLHLINNFNNELKKLDSPKFPIERSTI 
               
               
                   
               
               
                 FLVLVKKLINLNDLLITFIKLINRDNCKTTMSSDIENFLKINSQTVKLDDDDNSFFFNLNTTSMGEVNFNFK 
               
               
                   
               
               
                 NEILSNDLIYTLIGYNFDPTTNSELKSSISMNFINEEINVIDEFFKNDLLNFLSTDFHAGLDDDNGEEDDDE 
               
               
                   
               
               
                 EAGPGSTHPMGATGSQGSLSPEPVSTGNPSVPPTRNTSISEVNAENKRGNEAVLTPKETAKLNSLISLIDKR 
               
               
                   
               
               
                 LLSSQFKSKYPILMYNNCISYILNDILKHIFLKQQQQQLQSSSSQLHDTQPLTQQDTAQGIGSSSSNANNTN 
               
               
                   
               
               
                 SSFGNWWVFNSFIQEYMSLIGELVGLHDNLV* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 GEHITAPRLSFLRANS 
                 643 
                 0.94 
               
               
                 2 
                 QQQQQHSQTHNIYDND 
                 47 
                 0.93 
               
               
                 3 
                 VKLDDDDNSFFFNLNT 
                 838 
                 0.92 
               
               
                 3 
                 SGSATTGSTPRRGLSH 
                 577 
                 0.92 
               
               
                 3 
                 THNIYDNDNYMNYNFP 
                 55 
                 0.92 
               
               
                 3 
                 PGSTMQPSTSFAFHTS 
                 190 
                 0.92 
               
               
                 4 
                 MDSIIKPLVMQETYSN 
                 715 
                 0.91 
               
               
                 4 
                 YNFPPTSNRPRASTTT 
                 67 
                 0.91 
               
               
                 4 
                 QLPISEDDDPQNYTIP 
                 453 
                 0.91 
               
               
                 4 
                 PGYYFTPETKSEIQQQ 
                 19 
                 0.91 
               
               
                 5 
                 PVSTGNPSVPPTRNTS 
                 959 
                 0.90 
               
               
                 6 
                 QKLIASYPSASNTRNE 
                 481 
                 0.89 
               
               
                 6 
                 LRKINSPFTLDDFYNL 
                 351 
                 0.89 
               
               
                 7 
                 NGEEDDDEEAGPGSTH 
                 929 
                 0.88 
               
               
                 7 
                 PSTSFAFHTSHSTYNP 
                 196 
                 0.88 
               
               
                 8 
                 GNEAVLTPKETAKLNS 
                 985 
                 0.87 
               
               
                 8 
                 NTSISEVNAENKRGNE 
                 972 
                 0.87 
               
               
                 8 
                 GSQGSLSPEPVSTGNP 
                 950 
                 0.87 
               
               
                 8 
                 DLLNFLSTDFHAGLDD 
                 912 
                 0.87 
               
               
                 8 
                 DKTIVSPSDTDMTVSI 
                 386 
                 0.87 
               
               
                 8 
                 FRLPEYPTTSSSSLLS 
                 223 
                 0.87 
               
               
                 8 
                 TAQGIGSSSSNANNTN 
                 1065 
                 0.87 
               
               
                 9 
                 PSVPPTRNTSISEVNA 
                 965 
                 0.86 
               
               
                 9 
                 DFHAGLDDDNGEEDDD 
                 920 
                 0.86 
               
               
                 9 
                 VRLSYECYARQPALNR 
                 676 
                 0.86 
               
               
                 9 
                 SMLVDYFPNMEDKDNK 
                 413 
                 0.86 
               
               
                 9 
                 SETGVDDTKRSSKEST 
                 310 
                 0.86 
               
               
                 9 
                 SSELDQPIPAMAPSSP 
                 111 
                 0.86 
               
               
                 9 
                 QFKSKYPILMYNNCIS 
                 1013 
                 0.86 
               
               
                 10 
                 TSHSTYNPSFDSSNLY 
                 204 
                 0.85 
               
               
                 10 
                 PIPAMAPSSPLVSSAP 
                 117 
                 0.85 
               
               
                 11 
                 PGSELSHESHSVHTSP 
                 90 
                 0.84 
               
               
                 11 
                 LSVLDDDNWFVRLSYE 
                 666 
                 0.84 
               
               
                 11 
                 GESKYNYLGVMWNANI 
                 527 
                 0.84 
               
               
                 11 
                 QSNSQSGVPPPLYGTS 
                 170 
                 0.84 
               
               
                 11 
                 PLVSSAPYYYQQPSQQ 
                 126 
                 0.84 
               
               
                 12 
                 NNSSLLRNLMDSIIKP 
                 706 
                 0.83 
               
               
                 12 
                 QKIKTEPVAGNPFLQP 
                 599 
                 0.83 
               
               
                 13 
                 LVMQETYSNVDLVLYL 
                 722 
                 0.82 
               
               
                 13 
                 STTIFNDLLFHLTSVD 
                 324 
                 0.82 
               
               
                 13 
                 DSSNLYNSAFRLPEYP 
                 214 
                 0.82 
               
               
                 14 
                 YGTSSSIPPGSTMQPS 
                 182 
                 0.81 
               
               
                 15 
                 NEEINVIDEFFKNDLL 
                 899 
                 0.80 
               
               
                 15 
                 HELNDLNEIFNSDNNN 
                 554 
                 0.80 
               
               
                 16 
                 TTGTTSTTHPGSELSH 
                 81 
                 0.79 
               
               
                 16 
                 CYARQPALNRDLIQQI 
                 682 
                 0.79 
               
               
                 16 
                 SLSQQMGEHITAPRLS 
                 637 
                 0.79 
               
               
                 16 
                 NPHRTHKRQKSSVSNP 
                 4 
                 0.79 
               
               
                 16 
                 SSSSQLHDTQPLTQQD 
                 1049 
                 0.79 
               
               
                 17 
                 FASIAPSGSATTGSTP 
                 571 
                 0.78 
               
               
                 17 
                 SSSSNANNTNSSFGNW 
                 1071 
                 0.78 
               
               
                 18 
                 KFPIERSTIFLVLVKK 
                 784 
                 0.77 
               
               
                 18 
                 IFNSDNNNPFASIAPS 
                 562 
                 0.77 
               
               
                 18 
                 GVMWNANIVQEEIKQL 
                 535 
                 0.77 
               
               
                 19 
                 IGYNFDPTTNSELKSS 
                 877 
                 0.76 
               
               
                 19 
                 NDLIYTLIGYNFDPTT 
                 870 
                 0.76 
               
               
                 19 
                 ELKKLDSPKFPIERST 
                 776 
                 0.76 
               
               
                 19 
                 QLSQQTQSNSQSGVPP 
                 164 
                 0.76 
               
               
                 20 
                 HESHSVHTSPLKRTAS 
                 96 
                 0.75 
               
               
                 20 
                 NSELKSSISMNFINEE 
                 886 
                 0.75 
               
               
                 20 
                 HHHEEQSQEESLSQQM 
                 627 
                 0.75 
               
               
                 20 
                 HHHHHSHHHHHEEQSQ 
                 619 
                 0.75 
               
               
                 20 
                 SEIQQQQPQQQESQQQ 
                 29 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 730 
                 753 
                 747 
                 NVDLVLYLAILLEILPYLLLVKSS 
               
               
                 789 
                 813 
                 795 
                 RSTIFLVLVKKLINLNDLLITFIKL 
               
               
                 507 
                 522 
                 513 
                 LGKLIKLVYPNLLIKR 
               
               
                 467 
                 489 
                 480 
                 IPRLSIYKTYYIICQKLIASYPS 
               
               
                 434 
                 457 
                 453 
                 YHELLRTFLAIKILHDILIQLPIS 
               
               
                 759 
                 770 
                 767 
                 LKNLRLNLLHLI 
               
               
                 329 
                 338 
                 335 
                 NDLLFHLTSV 
               
               
                 113 
                 139 
                 130 
                 ELDQPIPAMAPSSPLVSSAPYYYQQPS 
               
               
                 716 
                 726 
                 720 
                 DSIIKPLVMQE 
               
               
                 675 
                 687 
                 679 
                 FVRLSYECYARQP 
               
               
                 998 
                 1063 
                 1037 
                 LNSLISLIDKRLLSSQFKSKYPILMYNNCISYILNDILKHI 
               
               
                   
                   
                   
                 FLKQQQQQLQSSSSQLHDTQPLTQQ 
               
               
                 694 
                 702 
                 696 
                 IQQIFLKNE 
               
               
                 661 
                 670 
                 666 
                 PTDVNLSVLD 
               
               
                 345 
                 354 
                 348 
                 TFLLSILRKI 
               
               
                 283 
                 292 
                 289 
                 ISSHLTLFSL 
               
               
                 174 
                 190 
                 179 
                 QSGVPPPLYGTSSSIPP 
               
               
                 267 
                 275 
                 270 
                 SSHVSALRQ 
               
               
                 1093 
                 1108 
                 1101 
                 IQEYMSLIGELVGLHD 
               
               
                 607 
                 630 
                 613 
                 AGNPFLQPLQTSHHHHHSHHHHHE 
               
               
                 869 
                 879 
                 875 
                 SNDLIYTLIGY 
               
               
                 398 
                 409 
                 402 
                 TVSIINQLLNFF 
               
               
                 95 
                 105 
                 103 
                 SHESHSVHTSP 
               
               
                 246 
                 265 
                 259 
                 QQSSALLPSGTLPPSILGTS 
               
               
                 412 
                 419 
                 417 
                 PSMLVDYF 
               
               
                 953 
                 960 
                 957 
                 GSLSPEPV 
               
               
                 646 
                 655 
                 651 
                 ITAPRLSFLR 
               
               
                 141 
                 155 
                 147 
                 QQNLSYHDHHHQQQQ 
               
               
                 541 
                 554 
                 553 
                 NIVQEEIKQLCDEH 
               
               
                 233 
                 239 
                 235 
                 SSSLLST 
               
               
                 531 
                 537 
                 533 
                 YNYLGVM 
               
               
                 572 
                 577 
                 573 
                 ASIAPS 
               
               
                 499 
                 505 
                 500 
                 KLILGQS 
               
               
                 387 
                 393 
                 390 
                 KTIVSPS 
               
               
                 987 
                 992 
                 990 
                 EAVLTP 
               
               
                 13 
                 24 
                 19 
                 KSSVSNPGYYFT 
               
               
                 198 
                 206 
                 203 
                 TSFAFHTSH 
               
               
                 962 
                 969 
                 968 
                 TGNPSVPP 
               
               
                 833 
                 841 
                 838 
                 INSQTVKLD 
               
               
                 219 
                 228 
                 225 
                 YNSAFRLPEY 
               
               
                 299 
                 308 
                 300 
                 QLQSQGSSFQ 
               
               
                 162 
                 168 
                 163 
                 GQQLSQQ 
               
               
                 44 
                 53 
                 49 
                 QQQQQQQQHS 
               
               
                   
               
            
           
           
               
               
            
               
                 21. IPF2971 
                   
               
               
                 MTSTITKTNNSITRSFEDDKFLLPQLKSLNKTWIFSEDAVINNSPTRHQKLTISQELKNKESMHDFLIRLGQ 
               
               
                   
               
               
                 KLKVDGRTILAATIYLHRFYMRVPISQSKYYVVSAALTISCKLNDNYRTPDKVALLSCNVKLPPNAKPIDEQ 
               
               
                   
               
               
                 SEMYWRWKDQLLFREELMLRKLNFDLNLTLPYEIRDHIFKNFMLLDQEDESVKLFSTHKLDILKMTTSLIES 
               
               
                   
               
               
                 LSSLPVILCYEMNIMFGTCLIITILEGKKIIDEKLNIPTAFLYRFLDTDSETCLKCFHFIKNLLKFSQDDPH 
               
               
                   
               
               
                 IISNKASAKRLLDIRSRTFHEIAKQGDLKQPQPQPQPQPQQHENETTTKEKKPEDNQGEGNNATEKIENGHT 
               
               
                   
               
               
                 TNSTNTDPKSQDNKVDVIEKKEAKEINKSETQDDHTQERSTIAAENKVPDTESNVTKSEITKSNNEIMAEKN 
               
               
                   
               
               
                 PDVKNSNSNSDDTGYTSNQLEQGKDTKNEELEKILDSEKISTPNNGTTTDKPAADVHDSTNGTNENSIGEKR 
               
               
                   
               
               
                 VLEQDSNDTNVDSPSSKIAKVE* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 DAVINNSPTRHQKLTI 
                 38 
                 0.95 
               
               
                 2 
                 NSTNTDPKSQDNKVDV 
                 362 
                 0.94 
               
               
                 2 
                 TCLIITILEGKKIIDE 
                 234 
                 0.94 
               
               
                 2 
                 AKPIDEQSEMYWRWKD 
                 138 
                 0.94 
               
               
                 3 
                 CKLNDNYRTPDKVALL 
                 113 
                 0.93 
               
               
                 4 
                 SEKISTPNNGTTTDKP 
                 469 
                 0.92 
               
               
                 5 
                 NGTTTDKPAADVHDST 
                 477 
                 0.89 
               
               
                 5 
                 NNEIMAEKNPDVKNSN 
                 424 
                 0.89 
               
               
                 5 
                 HENETTTKEKKPEDNQ 
                 330 
                 0.89 
               
               
                 5 
                 AALTISCKLNDNYRTP 
                 107 
                 0.89 
               
               
                 6 
                 SETQDDHTQERSTIAA 
                 389 
                 0.88 
               
               
                 6 
                 YWRWKDQLLFREELML 
                 148 
                 0.88 
               
               
                 7 
                 DVKNSNSNSDDTGYTS 
                 434 
                 0.87 
               
               
                 7 
                 PYEIRDHIFKNFMLLD 
                 175 
                 0.87 
               
               
                 8 
                 NNSITRSFEDDKFLLP 
                 9 
                 0.86 
               
               
                 8 
                 SEITKSNNEIMAEKNP 
                 418 
                 0.86 
               
               
                 9 
                 TESNVTKSEITKSNNE 
                 411 
                 0.85 
               
               
                 10 
                 NEELEKILDSEKISTP 
                 460 
                 0.84 
               
               
                 10 
                 DDTGYTSNQLEQGKDT 
                 443 
                 0.84 
               
               
                 10 
                 PQPQPQPQQHENETTT 
                 321 
                 0.84 
               
               
                 10 
                 NKTWIFSEDAVINNSP 
                 30 
                 0.84 
               
               
                 10 
                 SLPVILCYEMNIMFGT 
                 219 
                 0.84 
               
               
                 11 
                 AKEINKSETQDDHTQE 
                 383 
                 0.83 
               
               
                 12 
                 EKKPEDNQGEGNNATE 
                 338 
                 0.81 
               
               
                 13 
                 PISQSKYYVVSAALTI 
                 96 
                 0.80 
               
               
                 13 
                 RVLEQDSNDTNVDSPS 
                 504 
                 0.80 
               
               
                 14 
                 GRTILAATIYLHRFYM 
                 78 
                 0.79 
               
               
                 14 
                 TSTITKTNNSITRSFE 
                 2 
                 0.79 
               
               
                 15 
                 KVDVIEKKEAKEINKS 
                 374 
                 0.78 
               
               
                 15 
                 TEKIENGHTTNSTNTD 
                 352 
                 0.78 
               
               
                 15 
                 DPHIISNKASAKRLLD 
                 286 
                 0.78 
               
               
                 15 
                 EELMLRKLNFDLNLTL 
                 159 
                 0.78 
               
               
                 16 
                 NKESMHDFLIRLGQKL 
                 59 
                 0.77 
               
               
                 16 
                 NQLEQGKDTKNEELEK 
                 450 
                 0.77 
               
               
                 16 
                 NLLKFSQDDPHIISNK 
                 278 
                 0.77 
               
               
                 16 
                 TSLIESLSSLPVILCY 
                 211 
                 0.77 
               
               
                 17 
                 HEIAKQGDLKQPQPQP 
                 308 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 213 
                 228 
                 223 
                 LIESLSSLPVILCYEM 
               
               
                 81 
                 116 
                 106 
                 ILAATIYLHRFYMRVPISQSKYYVVSAALTISCKLN 
               
               
                 122 
                 138 
                 127 
                 PDKVALLSCNVKLPPNA 
               
               
                 267 
                 283 
                 272 
                 ETCLKCFHFIKNLLKFS 
               
               
                 232 
                 241 
                 238 
                 FGTCLIITIL 
               
               
                 20 
                 29 
                 23 
                 KFLLPQLKSL 
               
               
                 253 
                 262 
                 259 
                 IPTAFLYRFL 
               
               
                 195 
                 207 
                 199 
                 SVKLFSTHKLDIL 
               
               
                 171 
                 181 
                 173 
                 NLTLPYEIRDH 
               
               
                 64 
                 77 
                 73 
                 HDFLIRLGQKLKVD 
               
               
                 516 
                 523 
                 522 
                 DSPSSKIA 
               
               
                 296 
                 302 
                 297 
                 AKRLLDI 
               
               
                 50 
                 55 
                 54 
                 KLTISQ 
               
               
                 153 
                 158 
                 158 
                 DQLLFR 
               
               
                 316 
                 328 
                 319 
                 LKQPQPQPQPQPQ 
               
               
                 502 
                 508 
                 503 
                 EKRVLEQ 
               
               
                 285 
                 293 
                 287 
                 DDPHIISNK 
               
               
                   
               
            
           
           
               
               
            
               
                 22. IPF1798 
                   
               
               
                 MTPSSTKKIKQRRSTSCTVCRTIKRKCDGNTPCSNCLKRNQECIYPDVDKRKKRYSIEYITNLENTNQQLHD 
               
               
                   
               
               
                 QLQSLIDLKDNPYQLHLKITEILESSSSFLDNSETKSDSSLGSPELSKSEASLANSFTLGGELVVSSREQGA 
               
               
                   
               
               
                 NFHVHLNQQQQQQQPSPQSLSQSSASEVSTRSSPASPNSTISLAPQILRIPSRPFQQQTRQNLLRQSDLPLH 
               
               
                   
               
               
                 YPISGKTSGPNASNITGSIASTISGSRKSSISVDISPPPSLPVFPTSGPTLPTLLPEPLPRNDFDFAPKFFP 
               
               
                   
               
               
                 APGGKSNMAFGATTVYDADESMVMNVNQIEERWGTGIKLAKLRNVPNIQNRSSSSSSTLIKVNKRTIEEVIK 
               
               
                   
               
               
                 MITNSKAKKYFALAFKYFDRPILCYLIPRGKVIKLYEEICAHKNDLATVEDILGLYPTNQFISIELIAALIA 
               
               
                   
               
               
                 SGALYDDNIDCVREYLTLSKTEMFINNSGCLVFNESSYPKLQAMLVCALLELGLGELTTAWELSGIALRMGI 
               
               
                   
               
               
                 DLGFDSFIYDDSDKEIDNLRNLVFWGSYIIDKYAGLIFGRITMLYVDNSVPLIFLPNRQGKLPCLAQLIIDT 
               
               
                   
               
               
                 QPMISSIYETIPETKNDPEMSKKIFLERYNLLQGYNKSLGAWKRGLSREYFWNKSILINTITDESVDHSLKI 
               
               
                   
               
               
                 AYYLIFLIMNKPFLKLPIGSDIDTFIEIVDEMEIIMRYIPDDKHLLNLVVYYALVLMIQSLVAQVSYTNANN 
               
               
                   
               
               
                 YTQNSKFMNQLLFFIDRMGEVLRVDIWLICKKVHSNFQQKVEYLEKLMLDLTEKMEQRRRDEENLMMQQEEF 
               
               
                   
               
               
                 YAQQQQQQQQQQQQPKHEYHDHQQEQEQQEQLQEEHSEKDIKIEIKDEPQPQEEHIHQDYPMKEEEENLNQL 
               
               
                   
               
               
                 SEPQTNEEDNPAEDMLQNEQFMRMVDILFIRGIENDQEEGEEQQQQQQQQEQVQQEQVQQEQVQQDQMELEE 
               
               
                   
               
               
                 DELPQQMPTPPEQPDEPEIPQLPEILDPTFFNSIVDNNGSTFNNIFSFDTEGFRL* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 LPEILDFTFFNSIVDN 
                 958 
                 0.97 
               
               
                 2 
                 AGLIFGRITMLYVDNS 
                 538 
                 0.96 
               
               
                 3 
                 GKVIKLYEEICAHKND 
                 390 
                 0.94 
               
               
                 4 
                 QECIYPDVDKRKKPRY 
                 41 
                 0.93 
               
               
                 5 
                 MEIIMRYIPDDKHLLN 
                 680 
                 0.92 
               
               
                 5 
                 TTVYDADESMVMNVNQ 
                 301 
                 0.92 
               
               
                 5 
                 ASTISGSRKSSISVDI 
                 236 
                 0.92 
               
               
                 5 
                 CRTIKRKCDGNTPCSN 
                 20 
                 0.92 
               
               
                 6 
                 IWLICKKVHSNFQQKV 
                 746 
                 0.91 
               
               
                 7 
                 IRGIENDQEEGEEQQQ 
                 894 
                 0.89 
               
               
                 7 
                 HIHQDYPMKEEEENLN 
                 847 
                 0.89 
               
               
                 7 
                 YEEICAHKNDLATVED 
                 396 
                 0.89 
               
               
                 8 
                 LPIGSDIDTFIEIVDE 
                 664 
                 0.88 
               
               
                 8 
                 AALIASGALYDDNIDC 
                 428 
                 0.88 
               
               
                 9 
                 HYPISGKTSGPNASNI 
                 216 
                 0.87 
               
               
                 10 
                 KCDGNTPCSNCLKRNQ 
                 26 
                 0.86 
               
               
                 11 
                 PTPPEQPDEPEIPQLP 
                 944 
                 0.85 
               
               
                 11 
                 ELPQQMPTPPEQPDEP 
                 938 
                 0.85 
               
               
                 11 
                 EEVIKMITNSKAKKYF 
                 356 
                 0.85 
               
               
                 12 
                 EERWGTGIKLAKLRNV 
                 318 
                 0.84 
               
               
                 13 
                 KMEQRRRDEENLMMQQ 
                 774 
                 0.83 
               
               
                 13 
                 VLMIQSLVAQVSYTNA 
                 703 
                 0.83 
               
               
                 13 
                 SSREQGANFHVHLNQQ 
                 138 
                 0.83 
               
               
                 14 
                 EQLQEEHSEKDIKIEI 
                 822 
                 0.82 
               
               
                 14 
                 VAQVSYTNANNYTQNS 
                 710 
                 0.82 
               
               
                 14 
                 AQLIIDTQPMISSIYE 
                 570 
                 0.82 
               
               
                 15 
                 QMELEEDELPQQMPTP 
                 931 
                 0.81 
               
               
                 15 
                 LGAWKRGLSREYFWNK 
                 615 
                 0.81 
               
               
                 15 
                 ISSIYETIPETKNDPE 
                 580 
                 0.81 
               
               
                 15 
                 VPLIFLPNRQGKLPCL 
                 554 
                 0.81 
               
               
                 15 
                 DVDKRKKRYSIEYITN 
                 47 
                 0.81 
               
               
                 15 
                 DRPILCYLIPRGKVIK 
                 379 
                 0.81 
               
               
                 15 
                 FFAPGGKSNMAFGATT 
                 287 
                 0.81 
               
               
                 15 
                 QSSASEVSTRSSPASP 
                 166 
                 0.81 
               
               
                 16 
                 PQPQEEHIHQDYPMKE 
                 841 
                 0.80 
               
               
                 16 
                 SSSSSSTLIKVNKRTI 
                 340 
                 0.80 
               
               
                 17 
                 WELSGIALRMGIDLGF 
                 493 
                 0.79 
               
               
                 17 
                 SISVDISPPPSLPVFP 
                 246 
                 0.79 
               
               
                 17 
                 PQILRIPSRPFQQQTR 
                 189 
                 0.79 
               
               
                 18 
                 SIVDNNGSTFNNIFSF 
                 969 
                 0.78 
               
               
                 18 
                 GFDSFIYDDSDKEIDN 
                 507 
                 0.78 
               
               
                 19 
                 KRYSIEYITNLENTNQ 
                 53 
                 0.77 
               
               
                 19 
                 ESMVMNVNQIEERWGT 
                 308 
                 0.77 
               
               
                 19 
                 EPLPRNDFDFAPKFFP 
                 273 
                 0.77 
               
               
                 19 
                 LRQSDLPLHYPISGKT 
                 208 
                 0.77 
               
               
                 20 
                 PQTNEEDNPAEDMLQN 
                 867 
                 0.76 
               
               
                 20 
                 KIEIKDEPQPQEEHIH 
                 834 
                 0.76 
               
               
                 20 
                 LRMGIDLGFDSFIYDD 
                 500 
                 0.76 
               
               
                 20 
                 SPPPSLPVFPTSGPTL 
                 252 
                 0.76 
               
               
                 21 
                 QQQQPKHEYHDHQQEQ 
                 803 
                 0.75 
               
               
                 21 
                 IPETKNDPEMSKKIFL 
                 587 
                 0.75 
               
               
                 21 
                 REYLTLSKTEMFINNS 
                 445 
                 0.75 
               
               
                 21 
                 HKNDLATVEDILGLYP 
                 402 
                 0.75 
               
               
                 21 
                 DSSLGSPELSKSEASL 
                 110 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 689 
                 716 
                 700 
                 DDKHLLNLVVYYALIVLMIQSLVAQVSYT 
               
               
                 470 
                 487 
                 480 
                 YPKLQAMLVCALLELGLG 
               
               
                 368 
                 404 
                 384 
                 KKYFALAFKYFDRPILCYLIPRGKVIKLYEEICAHKN 
               
               
                 565 
                 575 
                 569 
                 KLPCLAQLIID 
               
               
                 546 
                 560 
                 557 
                 TMLYVDNSVPLIFLP 
               
               
                 642 
                 659 
                 653 
                 VDHSLKIAYYLIFLIMNK 
               
               
                 741 
                 756 
                 751 
                 VLRVDIWLICKKVHSN 
               
               
                 16 
                 26 
                 20 
                 SCTVCRTIKRK 
               
               
                 207 
                 220 
                 216 
                 LLRQSDLPLHYPIS 
               
               
                 406 
                 436 
                 429 
                 LATVEDILGLYPTNQFISIELIAALIASGAL 
               
               
                 245 
                 262 
                 257 
                 SSISVDISPPPSLPVFPT 
               
               
                 33 
                 48 
                 46 
                 CSNCLKRNQECIYPDV 
               
               
                 132 
                 140 
                 134 
                 GGELVVSSR 
               
               
                 83 
                 102 
                 88 
                 NPYQLHLKITEILESSSSFL 
               
               
                 440 
                 451 
                 446 
                 NIDCVREYLTLS 
               
               
                 184 
                 199 
                 189 
                 TISLAPQILRIPSRPF 
               
               
                 661 
                 667 
                 663 
                 FLKLPIG 
               
               
                 459 
                 467 
                 462 
                 NSGCLVFNE 
               
               
                 70 
                 80 
                 77 
                 LHDQLQSLIDL 
               
               
                 264 
                 274 
                 273 
                 GPTLPTLLPEP 
               
               
                 145 
                 153 
                 147 
                 NFHVHLNQQ 
               
               
                 888 
                 895 
                 892 
                 MVDILFIR 
               
               
                 729 
                 735 
                 733 
                 NQLLFFI 
               
               
                 914 
                 929 
                 919 
                 QEQVQQEQVQQEQVQQ 
               
               
                 758 
                 770 
                 764 
                 QQKVEYLEKLMLD 
               
               
                 524 
                 543 
                 529 
                 RNLVFWGSYIIDKYAGLIFG 
               
               
                 344 
                 350 
                 347 
                 SSTLIKV 
               
               
                 955 
                 965 
                 959 
                 IPQLPEILDPT 
               
               
                 325 
                 334 
                 330 
                 IKLAKLRNVP 
               
               
                 599 
                 612 
                 608 
                 KIFLERYNLLQGYN 
               
               
                 155 
                 167 
                 161 
                 QQQQPSPQSLSQS 
               
               
                 629 
                 636 
                 634 
                 NKSILINT 
               
               
                 283 
                 289 
                 285 
                 APKFFPA 
               
               
                 300 
                 306 
                 301 
                 ATTVYDA 
               
               
                 580 
                 586 
                 581 
                 ISSIYET 
               
               
                 791 
                 806 
                 795 
                 EFYAQQQQQQQQQQQQ 
               
               
                 121 
                 128 
                 128 
                 SEASLANS 
               
               
                 169 
                 175 
                 169 
                 ASEVSTR 
               
               
                 507 
                 514 
                 509 
                 GFDSFIYD 
               
               
                 808 
                 814 
                 809 
                 KHEYHDH 
               
               
                 356 
                 361 
                 357 
                 EEVIKM 
               
               
                   
               
            
           
           
               
               
            
               
                 23. IPF4805 
                   
               
               
                 MSTVPQVTQDDYTETLKVWRSFKVAQLKDVCRSLELNVGGRKQDLVDRGEAFLSSKFNNNDQIGFHAAKSLI 
               
               
                   
               
               
                 FMRLQGDPLPSYRDMHYAIRTGRFKLTAPTLIGTSSSTNQLSNIHSGDSKPYKGHTLYFKATPLYRFLRLIH 
               
               
                   
               
               
                 STPMLLIPNGRNSVQTCHFIFTEEEYKFLQDKPPHIKLYILCGIPDMQRSNATNNVSIEYPVETVIYFNKHE 
               
               
                   
               
               
                 FKDTFRGISGETNTAVPVDITKYINSPPQRNEIVFCHSANNAGYMMYLYLVEVIPAERLIEQVQNRPAIPKS 
               
               
                   
               
               
                 ETIRNIKDMSRYDGIQTTKLPLRDPLSYTKLANPTKSVHCDHYMCFNGMLFIEQQRLVDEWKCPVCSREIKF 
               
               
                   
               
               
                 EDLRISEYFEEIIKNVGPDVDEIIIMQDGSWKPVVGDDTNTTKKRTESASPEAIILLSDDEDDVSADEVDAN 
               
               
                   
               
               
                 VHLENKEDESVNINRVDNTPEAEVDITESNNNQETQIDNESIQSDDLTEYLIDHEHQQHEEASDKVEDNNPT 
               
               
                   
               
               
                 LPSQQSPQAETNNDETSNMKTTLQEDTSAPLPKNGVQENDAPLGDAIDTEQNLREDQTAEAVDPADSPISVI 
               
               
                   
               
               
                 NVTLDPPNEANKENSTESSISLSNLSPKNRESSLSSSSPQSVPPSMITPISPMSAQASSDKAQVLHGDSNTS 
               
               
                   
               
               
                 NQPRYTSSPDSAASPLSLTGPNDINEENRTPQSHNLNNTDALHGQDSSNSQAVSNSRSIQSVPTAAVSSKNQ 
               
               
                   
               
               
                 GNQHSDDQIRSLNEEIKKLRQALYYRDLYIKRLPLNQQHALLQQQQQQQLQLQQLSQQRPNDHQIHHFQQQQ 
               
               
                   
               
               
                 LLQQQQQRQLRQLEQQQRLQRQQWQQQQQLLQQQQQQLPRQLPLQSPQQLPQQQHLSPEDQSQFLQLTQLPQ 
               
               
                   
               
               
                 FRRLQQLQSQQRQSQQRQANPHQQHQQNYLQQPQHNNAQLHLNRNSHQLPQQQQQQQHHHYQQQQQQQQQQQ 
               
               
                   
               
               
                 RLQLPQQLRSSPQNRSFQTQPNEQQRVNSLSRSTDATPLSRQIVLDFGTSVPLPTQSSRPTLEEQGSFNLNL 
               
               
                   
               
               
                 LRHTPNLQTVASHSPWSPVATEPKNRSFSDSNIAVVNGLNESDPIEDRPLASLSGRSKSTNNMSNHNTSNVS 
               
               
                   
               
               
                 SSNYQVSEKQQQVHRLQSINANSNKKEDTEVETTTDTNLQQGSSAENTTDEQNSFRCNVQKPMLAIKNSDPS 
               
               
                   
               
               
                 QNHGQVEDTQTKNSINGTSTGVGGTAVFEGNSKLQTNSVQSHSNSPRKEQNSTSVVPNGNPQQIVIGNPSSM 
               
               
                   
               
               
                 VEKKDNGIDYNRNTFQIEDSVVNFVGRDTVNRIIGLTNLKDIQKVVENINNRKIVIDSNVEADRNRKRMILQ 
               
               
                   
               
               
                 KFDFDTKSLISDLMKNGGSNYEKSKLINTRRGEKSRLATHWDDKLEKNLSKYNAELQKLDKTLMLLRKQAES 
               
               
                   
               
               
                 IEARDAQIGGQSLNSTPVDNANSRGTPSSETDTAAGQSPKKNHLVNIPPQTNQSASQNETLQLSSIVTPSNR 
               
               
                   
               
               
                 DSSNKIRSGPPLQTSQVPTSKRQRVIGMLGIELNEDALKISDRKHGLQNSVTPINNKIKNISLGASNTNNCK 
               
               
                   
               
               
                 DRLGDLQTQFSLNQNITSGTMHDPIVLDMSDEE* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 HGDSNTSNQPRYTSSP 
                 642 
                 0.94 
               
               
                 1 
                 KLPLRDPLSYTKLANP 
                 307 
                 0.94 
               
               
                 1 
                 NSVQSHSNSPRKEQNS 
                 1189 
                 0.94 
               
               
                 2 
                 NEENRTPQSHNLNNTD 
                 673 
                 0.93 
               
               
                 3 
                 SNQPRYTSSPDSAASP 
                 648 
                 0.91 
               
               
                 3 
                 ISVINVTLDPPNEANK 
                 573 
                 0.91 
               
               
                 3 
                 TKYINSPPQRNEIVFC 
                 237 
                 0.91 
               
               
                 3 
                 VETVIYFNKHEFKDTF 
                 206 
                 0.91 
               
               
                 3 
                 LCGIPDMQRSNATNNV 
                 185 
                 0.91 
               
               
                 3 
                 RGTPSSETDTAAGQSP 
                 1392 
                 0.91 
               
               
                 3 
                 PRKEQNSTSVVPNGNP 
                 1198 
                 0.91 
               
               
                 4 
                 PSMITPISPMSAQASS 
                 620 
                 0.90 
               
               
                 4 
                 HEEASDKVEDNNPTLP 
                 491 
                 0.90 
               
               
                 4 
                 ATHWDDKLEKNLSKYN 
                 1334 
                 0.90 
               
               
                 5 
                 SSPQSVPPSMITPISP 
                 613 
                 0.89 
               
               
                 5 
                 GVQENDAPLGDAIDTE 
                 539 
                 0.89 
               
               
                 6 
                 PQVTQDDYTETLKVWR 
                 5 
                 0.88 
               
               
                 6 
                 VDEWKCPVCSREIKFE 
                 346 
                 0.88 
               
               
                 7 
                 QIVIGNPSSMVEKKDN 
                 1215 
                 0.87 
               
               
                 7 
                 SGRSKSTNNMSNHNTS 
                 1062 
                 0.87 
               
               
                 8 
                 SRSTDATPLSRQIVLD 
                 967 
                 0.86 
               
               
                 8 
                 PSYRDMHYAIRTGRFK 
                 82 
                 0.86 
               
               
                 8 
                 LQEDTSAPLPKNGVQE 
                 527 
                 0.86 
               
               
                 8 
                 PEAEVDITESNNNQET 
                 452 
                 0.86 
               
               
                 8 
                 LRISEYFEEIIKNVGP 
                 363 
                 0.86 
               
               
                 8 
                 IRNIKDMSRYDGIQTT 
                 291 
                 0.86 
               
               
                 8 
                 CHFIFTEEEYKFLQDK 
                 161 
                 0.86 
               
               
                 8 
                 SKLINTRRGEKSRLAT 
                 1320 
                 0.86 
               
               
                 8 
                 IHSGDSKPYKGHTLYF 
                 116 
                 0.86 
               
               
                 8 
                 ENTTDEQNSFRCNVQK 
                 1126 
                 0.86 
               
               
                 9 
                 VDRGEAFLSSKFNNND 
                 46 
                 0.85 
               
               
                 9 
                 QDGSWKPVVGDDTNTT 
                 387 
                 0.85 
               
               
                 9 
                 RPAIPKSETIRNIKDM 
                 282 
                 0.85 
               
               
                 9 
                 NVSIEYPVETVIYFNK 
                 199 
                 0.85 
               
               
                 9 
                 KSLISDLMKNGGSNYE 
                 1303 
                 0.85 
               
               
                 9 
                 KIVIDSNVEADRNRKR 
                 1277 
                 0.85 
               
               
                 9 
                 SMVEKKDNGIDYNRNT 
                 1223 
                 0.85 
               
               
                 9 
                 LQTVASHSPWSPVATE 
                 1015 
                 0.85 
               
               
                 10 
                 KRTESASPEAIILLSD 
                 404 
                 0.84 
               
               
                 10 
                 RGISGETNTAVPVDIT 
                 222 
                 0.84 
               
               
                 10 
                 DRLGDLQTQFSLNQNI 
                 1513 
                 0.84 
               
               
                 10 
                 TFQIEDSVVNFVGRDT 
                 1238 
                 0.84 
               
               
                 10 
                 TGVGGTAVFEGNSKLQ 
                 1172 
                 0.84 
               
               
                 10 
                 HGQVEDTQTKNSINGT 
                 1155 
                 0.84 
               
               
                 10 
                 SFRCNVQKPMLAIKNS 
                 1134 
                 0.84 
               
               
                 11 
                 QSVPTAAVSSKNQGNQ 
                 708 
                 0.83 
               
               
                 11 
                 LGDAIDTEQNLREDQT 
                 547 
                 0.83 
               
               
                 11 
                 PVVGDDTNTTKKRTES 
                 393 
                 0.83 
               
               
                 11 
                 SVHCDHYMCFNGMLFI 
                 325 
                 0.83 
               
               
                 11 
                 TPMLLIPNGRNSVQTC 
                 146 
                 0.83 
               
               
                 11 
                 LSSIVTPSNRDSSNKI 
                 1431 
                 0.83 
               
               
                 11 
                 DTAAGQSPKKNHLVNI 
                 1400 
                 0.83 
               
               
                 11 
                 EDRPLASLSGRSKSTN 
                 1054 
                 0.83 
               
               
                 12 
                 VNINRVDNTPEAEVDI 
                 443 
                 0.82 
               
               
                 12 
                 QSLNSTPVDNANSRGT 
                 1379 
                 0.82 
               
               
                 12 
                 AESIEARDAQIGGQSL 
                 1366 
                 0.82 
               
               
                 12 
                 NGLNESDPIEDRPLAS 
                 1045 
                 0.82 
               
               
                 12 
                 RSFSDSNIAVVNGLNE 
                 1034 
                 0.82 
               
               
                 12 
                 PTLIGTSSSTNQLSNI 
                 101 
                 0.82 
               
               
                 13 
                 NRSFQTQPNEQQRVNS 
                 950 
                 0.81 
               
               
                 13 
                 AEAVDPADSPISVINV 
                 563 
                 0.81 
               
               
                 13 
                 FEEIIKNVGPDVDEII 
                 369 
                 0.81 
               
               
                 13 
                 MLFIEQQRLVDEWKCP 
                 337 
                 0.81 
               
               
                 13 
                 SASQNETLQLSSIVTP 
                 1422 
                 0.81 
               
               
                 13 
                 HSPWSPVATEPKNRSF 
                 1021 
                 0.81 
               
               
                 14 
                 HNNAQLHLNRNSHQLP 
                 899 
                 0.80 
               
               
                 14 
                 LPSQQSPQAETNNDET 
                 505 
                 0.80 
               
               
                 14 
                 PVCSREIKFEDLRISE 
                 352 
                 0.80 
               
               
                 14 
                 DGIQTTKLPLRDPLSY 
                 301 
                 0.80 
               
               
                 14 
                 SGTMHDPIVLDMSDEE 
                 1530 
                 0.80 
               
               
                 14 
                 KHGLQNSVTPINNKIK 
                 1484 
                 0.80 
               
               
                 14 
                 TLYFKATPLYRFLRLI 
                 128 
                 0.80 
               
               
                 15 
                 TQSSRPTLEEQGSFNL 
                 991 
                 0.79 
               
               
                 15 
                 LREDQTAEAVDPADSP 
                 557 
                 0.79 
               
               
                 15 
                 AIILLSDDEDDVSADE 
                 413 
                 0.79 
               
               
                 15 
                 CHSANNAGYMMYLYLV 
                 252 
                 0.79 
               
               
                 15 
                 NRKRMILQKFDFDTKS 
                 1289 
                 0.79 
               
               
                 15 
                 KNSINGTSTGVGGTAV 
                 1164 
                 0.79 
               
               
                 16 
                 KSLIFMRLQGDPLPSY 
                 69 
                 0.78 
               
               
                 16 
                 SAASPLSLTGPNDINE 
                 659 
                 0.78 
               
               
                 16 
                 PQAETNNDETSNMKTT 
                 511 
                 0.78 
               
               
                 16 
                 ENKEDESVNINRVDNT 
                 436 
                 0.78 
               
               
                 16 
                 ADEVDANVHLENKEDE 
                 426 
                 0.78 
               
               
                 16 
                 GPPLQTSQVPTSKRQR 
                 1449 
                 0.78 
               
               
                 16 
                 DYTETLKVWRSFKVAQ 
                 11 
                 0.78 
               
               
                 17 
                 EQQRVNSLSRSTDATP 
                 959 
                 0.77 
               
               
                 17 
                 QQLRSSPQNRSFQTQP 
                 942 
                 0.77 
               
               
                 17 
                 KKLRQALYYRDLYIKR 
                 737 
                 0.77 
               
               
                 17 
                 ALHGQDSSNSQAVSNS 
                 689 
                 0.77 
               
               
                 18 
                 DDQIRSLNEEIKKLRQ 
                 726 
                 0.76 
               
               
                 18 
                 GGRKQDLVDRGEAFLS 
                 39 
                 0.76 
               
               
                 18 
                 FNKHEFKDTFRGISGE 
                 212 
                 0.76 
               
               
                 18 
                 HLVNIPPQTNQSASQN 
                 1411 
                 0.76 
               
               
                 18 
                 NVSSSNYQVSEKQQQV 
                 1078 
                 0.76 
               
               
                 19 
                 LKDIQKVVENINNRKI 
                 1263 
                 0.75 
               
               
                 19 
                 NFVGRDTVNRIIGLTN 
                 1247 
                 0.75 
               
               
                 19 
                 NGIDYNRNTFQIEDSV 
                 1230 
                 0.75 
               
               
                 19 
                 TEVETTTDTNLQQGSS 
                 1109 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 261 
                 279 
                 266 
                 MMYLYLVEVIPAERLIEQV 
               
               
                 171 
                 189 
                 183 
                 KFLQDKPPHIKLYILCGIP 
               
               
                 247 
                 255 
                 252 
                 NEIVFCHSA 
               
               
                 339 
                 357 
                 352 
                 FIEQQRLVDEWKCPVCSRE 
               
               
                 1428 
                 1437 
                 1432 
                 TLQLSSIVTP 
               
               
                 158 
                 165 
                 161 
                 VQTCHFIF 
               
               
                 322 
                 333 
                 328 
                 PTKSVHCDHYMC 
               
               
                 15 
                 37 
                 33 
                 TLKVWRSFKVAQLKDVCRSLELN 
               
               
                 201 
                 214 
                 203 
                 SIEYPVETVIYFNK 
               
               
                 972 
                 992 
                 978 
                 ATPLSRQIVLDFGTSVPLPTQ 
               
               
                 563 
                 581 
                 575 
                 AEAVDPADSPISVINVTLD 
               
               
                 1242 
                 1249 
                 1247 
                 EDSVVNFV 
               
               
                 1040 
                 1046 
                 1044 
                 NIAVVNG 
               
               
                 707 
                 718 
                 712 
                 IQSVPTAAVSSK 
               
               
                 935 
                 947 
                 941 
                 QQRLQLPQQLRSS 
               
               
                 430 
                 436 
                 432 
                 DANVHLE 
               
               
                 231 
                 237 
                 233 
                 AVPVDIT 
               
               
                 738 
                 778 
                 772 
                 KLRQALYYRDLYIKRLPLNQQHALLQQQQQQQLQLQQLSQQ 
               
               
                 1409 
                 1416 
                 1414 
                 KNHLVNIP 
               
               
                 1081 
                 1099 
                 1096 
                 SSNYQVSEKQQQVHRLQSI 
               
               
                 411 
                 418 
                 414 
                 PEAIILLS 
               
               
                 854 
                 874 
                 859 
                 SQFLQLTQLPQFRRLQQLQSQ 
               
               
                 819 
                 851 
                 833 
                 QQQLLQQQQQQLPRQLPLQSPQQLPQQQHLSPE 
               
               
                 126 
                 152 
                 139 
                 GHTLYFKATPLYRFLRLIHSTPMLLIP 
               
               
                 1014 
                 1029 
                 1018 
                 NLQTVASHSPWSPVAT 
               
               
                 1276 
                 1283 
                 1281 
                 RKIVIDSN 
               
               
                 658 
                 667 
                 663 
                 DSAASPLSLT 
               
               
                 1535 
                 1541 
                 1537 
                 DPIVLDM 
               
               
                 4 
                 10 
                 6 
                 VPQVTQD 
               
               
                 1266 
                 1272 
                 1267 
                 IQKVVEN 
               
               
                 1214 
                 1220 
                 1216 
                 QQIVIGN 
               
               
                 783 
                 797 
                 791 
                 HQIHHFQQQQLLQQQ 
               
               
                 1449 
                 1460 
                 1454 
                 GPPLQTSQVPTS 
               
               
                 885 
                 897 
                 896 
                 PHQQHQQNYLQQP 
               
               
                 637 
                 643 
                 640 
                 KAQVLHG 
               
               
                 305 
                 319 
                 311 
                 TTKLPLRDPLSYTKL 
               
               
                 609 
                 633 
                 617 
                 SLSSSSPQSVPPSMITPISPMSAQA 
               
               
                 98 
                 106 
                 101 
                 LTAPTLIGT 
               
               
                 64 
                 75 
                 69 
                 GFHAAKSLIFMR 
               
               
                 1136 
                 1147 
                 1137 
                 RCNVQKPMLAIK 
               
               
                 1517 
                 1523 
                 1521 
                 DLQTQFS 
               
               
                 1205 
                 1210 
                 1206 
                 TSVVPN 
               
               
                 391 
                 397 
                 393 
                 WKPVVGD 
               
               
                 911 
                 933 
                 922 
                 HQLPQQQQQQQHHHYQQQQQQQQ 
               
               
                 480 
                 489 
                 485 
                 TEYLIDHEHQ 
               
               
                 1303 
                 1308 
                 1306 
                 KSLISD 
               
               
                 595 
                 601 
                 598 
                 SISLSNL 
               
               
                 505 
                 511 
                 508 
                 LPSQQSP 
               
               
                 373 
                 386 
                 382 
                 IKNVGPDVDEIIIM 
               
               
                 1488 
                 1493 
                 1488 
                 QNSVTP 
               
               
                 1005 
                 1012 
                 1009 
                 NLNLLRHT 
               
               
                 1358 
                 1364 
                 1362 
                 TLMLLRK 
               
               
                 78 
                 84 
                 79 
                 GDPLPSY 
               
               
                 1188 
                 1194 
                 1189 
                 TNSVQSH 
               
               
                 532 
                 538 
                 537 
                 SAPLPKN 
               
               
                 901 
                 907 
                 905 
                 NAQLHLN 
               
               
                 799 
                 812 
                 802 
                 QRQLRQLEQQQRLQ 
               
               
                 698 
                 704 
                 698 
                 SQAVSNS 
               
               
                 1348 
                 1356 
                 1353 
                 YNAELQKLD 
               
               
                 86 
                 91 
                 91 
                 DMHYAI 
               
               
                   
               
            
           
           
               
               
            
               
                 24. RBT4 
                   
               
               
                 MKFSQVATTAAIFAGLTTAEIAYVTQTRGVTVGETATVATTVTVGATVTGGDQGQDQVQQSAAPEAGDIQQS 
               
               
                   
               
               
                 AVPEADDIQQSAVPEAEPTADADGGNGIAITEVFTTTIMGQEIVYSGVYYSYGEEHTYGDVQVQTLTIGGGG 
               
               
                   
               
               
                 FPSDDQYPTTEVSAEASPSAVTTSSAVATPDAKVPDSTKDASQPAATTASGSSSGSNDFSGVKDTQFAQQIL 
               
               
                   
               
               
                 DAHNKKRARHGVPDLTWDATGYEYAQKFRDQSSCRGNSHTSSGTYGETXAVGYADGAAALQAWYEEAGKDGL 
               
               
                   
               
               
                 SYSYGSSSVYNHFTQVVWKSTTKLGCAYKDCRAQNWGLYVVCSYDPAGNVMGTDPKTGKSYMAENVLRPQ* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 NVMGTDPKTGKSYMAE 
                 337 
                 0.91 
               
               
                 1 
                 TLTIGGGGFPSDDQYP 
                 137 
                 0.91 
               
               
                 2 
                 DLTWDATGYEYAQKFR 
                 230 
                 0.90 
               
               
                 3 
                 TVTVGATVTGGDQGQD 
                 41 
                 0.89 
               
               
                 3 
                 TATVATTVTVGATVTG 
                 35 
                 0.89 
               
               
                 3 
                 CRAQNWGLYVVCSYDP 
                 319 
                 0.89 
               
               
                 4 
                 SAVPEAEPTADADGGN 
                 83 
                 0.88 
               
               
                 5 
                 AGDIQQSAVPEADDIQ 
                 66 
                 0.87 
               
               
                 5 
                 QFAQQILDAHNKKRAR 
                 210 
                 0.87 
               
               
                 5 
                 AVATPDAKVPDSTKDA 
                 170 
                 0.87 
               
               
                 6 
                 TKLGCAYKDCRAQNWG 
                 310 
                 0.86 
               
               
                 6 
                 TGYEYAQKFRDQSSCR 
                 236 
                 0.86 
               
               
                 6 
                 YVTQTRGVTVGETATV 
                 23 
                 0.86 
               
               
                 6 
                 SGVYYSYGEEHTYGDV 
                 118 
                 0.86 
               
               
                 7 
                 YVVCSYDPAGNVMGTD 
                 327 
                 0.85 
               
               
                 7 
                 TSSGTYGETXAVGYAD 
                 256 
                 0.85 
               
               
                 7 
                 EASPSAVTTSSAVATP 
                 159 
                 0.85 
               
               
                 7 
                 GQEIVYSGVYYSYGEE 
                 112 
                 0.85 
               
               
                 8 
                 QVQQSAAPEAGDIQQS 
                 57 
                 0.84 
               
               
                 9 
                 YGSSSVYNHFTQVVWK 
                 292 
                 0.83 
               
               
                 9 
                 GEEHTYGDVQVQTLTI 
                 125 
                 0.83 
               
               
                 10 
                 ARHGVPDLTWDATGYE 
                 224 
                 0.82 
               
               
                 10 
                 TTAEIAYVTQTRGVTV 
                 17 
                 0.82 
               
               
                 10 
                 GGFPSDDQYPTTEVSA 
                 143 
                 0.82 
               
               
                 11 
                 SGSSSGSNDFSGVKDT 
                 194 
                 0.81 
               
               
                 12 
                 GETXAVGYADGAAALQ 
                 262 
                 0.80 
               
               
                 13 
                 ADDIQQSAVPEAEPTA 
                 77 
                 0.79 
               
               
                 13 
                 TVTGGDQGQDQVQQSA 
                 47 
                 0.79 
               
               
                 13 
                 EEAGKDGLSYSYGSSS 
                 281 
                 0.79 
               
               
                 14 
                 EPTADADGGNGIAITE 
                 89 
                 0.78 
               
               
                 14 
                 KFRDQSSCRGNSHTSS 
                 243 
                 0.78 
               
               
                 15 
                 QPAATTASGSSSGSND 
                 187 
                 0.75 
               
               
                 15 
                 AKVPDSTKDASQPAAT 
                 176 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 324 
                 333 
                 329 
                 WGLYVVCSYD 
               
               
                 113 
                 125 
                 119 
                 QEIVYSGVYYSYG 
               
               
                 35 
                 47 
                 41 
                 TATVATTVTVGAT 
               
               
                 130 
                 138 
                 136 
                 YGDVQVQTL 
               
               
                 288 
                 307 
                 303 
                 LSYSYGSSSVYNHFTQVVWK 
               
               
                 311 
                 319 
                 316 
                 KLGCAYKDC 
               
               
                 71 
                 77 
                 72 
                 QSAVPEA 
               
               
                 82 
                 88 
                 83 
                 QSAVPEA 
               
               
                 157 
                 181 
                 168 
                 SAEASPSAVTTSSAVATPDAKVPDS 
               
               
                 55 
                 63 
                 61 
                 QDQVQQSAA 
               
               
                 212 
                 218 
                 213 
                 AQQILDA 
               
               
                 18 
                 27 
                 24 
                 TAEIAYVTQT 
               
               
                 4 
                 16 
                 13 
                 SQVATTAAIFAGL 
               
               
                 272 
                 279 
                 277 
                 GAAALQAW 
               
               
                 225 
                 231 
                 229 
                 RHGVPDL 
               
               
                 186 
                 191 
                 188 
                 SQPAAT 
               
               
                   
               
            
           
           
               
               
            
               
                 25. IPF5761 
                   
               
               
                 MTKEQIDEPRYKRIAVIGGGPTGLAAVKALSLEPVNFSCIDLFERRDRLGGLWYHHGDKSLVKPEIPSLSPS 
               
               
                   
               
               
                 QEEIVSDNATPADEYFSAIYEYMETNIVHQIMEYSGVAFPANSKKYPTRSQVLEYIDDYIKSIPKDTVNISI 
               
               
                   
               
               
                 NSNVVSLEKVNEIWHIEIEDVIKKTRAKLRYDAVIIANGHFSNPYIPDVPGLSSWNKNYPGTITHSKYYESP 
               
               
                   
               
               
                 AKFRDKRVLVVGNSASGVDISIQLSVCAKDVFVSIRDQESPHFEDGFCKHIGLIEEYNYETRSVRTTDREVV 
               
               
                   
               
               
                 SDIDYVIFCTGYLYALPFLKQERNITDGFQVYDLYKQIFNIYDPSLTFLALLRDVIPMPISESQAALIARVY 
               
               
                   
               
               
                 SGRYKLPPTEEMERYYQLELKEKGRGGKFHNYKYPRDVAYCQMLQTLIDEQGLHTPGLVAPIWDESLIKKRS 
               
               
                   
               
               
                 ETRAEKNARLKNVVEHVKRLRAEGKDFSLLE* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 LEYIDDYIKSIPKDTV 
                 125 
                 0.94 
               
               
                 2 
                 DAVIIANGHFSNPYIP 
                 176 
                 0.92 
               
               
                 3 
                 ESLIKKRSETRAEKNA 
                 425 
                 0.91 
               
               
                 3 
                 LKEKGRGGKFHNYKYP 
                 380 
                 0.91 
               
               
                 4 
                 KFHNYKYPRDVAYCQM 
                 388 
                 0.88 
               
               
                 4 
                 AALIARVYSGRYKLPP 
                 353 
                 0.88 
               
               
                 4 
                 PGTITHSKYYESPAKF 
                 204 
                 0.88 
               
               
                 S 
                 QTLIDEQGLHTPGLVA 
                 405 
                 0.87 
               
               
                 5 
                 DREVVSDIDYVIFCTG 
                 284 
                 0.87 
               
               
                 6 
                 QLSVCAKDVFVSIRDQ 
                 239 
                 0.86 
               
               
                 7 
                 PPTEEMERYYQLELKE 
                 367 
                 0.85 
               
               
                 7 
                 YETRSVRTTDREVVSD 
                 275 
                 0.85 
               
               
                 7 
                 NISINSNVVSLEKVNE 
                 141 
                 0.85 
               
               
                 8 
                 GGLWYHHGDKSLVKPE 
                 50 
                 0.84 
               
               
                 8 
                 IAVIGGGPTGLAAVKA 
                 14 
                 0.84 
               
               
                 9 
                 GLIEEYNYETRSVRTT 
                 268 
                 0.83 
               
               
                 9 
                 VNEIWHIEIEDVIKKT 
                 154 
                 0.83 
               
               
                 10 
                 FSAIYEYMETNIVHQI 
                 88 
                 0.82 
               
               
                 10 
                 TKEQIDEPRYKRIAVI 
                 2 
                 0.82 
               
               
                 11 
                 FSCIDLFERRDRLGGL 
                 37 
                 0.81 
               
               
                 11 
                 FVSIRDQESPHFEDGF 
                 248 
                 0.81 
               
               
                 11 
                 VHQIMEYSGVAFPANS 
                 100 
                 0.81 
               
               
                 12 
                 FNIYDPSLTFLALLRD 
                 327 
                 0.79 
               
               
                 12 
                 GLSSWNKNYPGTITHS 
                 195 
                 0.79 
               
               
                 13 
                 SETRAEKNARLKNVVE 
                 432 
                 0.77 
               
               
                 14 
                 DLYKQIFNIYDPSLTF 
                 321 
                 0.76 
               
               
                 15 
                 KALSLEPVNFSCIDLF 
                 28 
                 0.7S 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 233 
                 252 
                 241 
                 GVDISIQLSVCAKDVFVSIR 
               
               
                 285 
                 308 
                 294 
                 REVVSDIDYVIFCTGYLYALPFLK 
               
               
                 145 
                 154 
                 151 
                 NSNVVSLEKV 
               
               
                 395 
                 408 
                 401 
                 PRDVAYCQMLQTLI 
               
               
                 222 
                 229 
                 225 
                 KRVLVVGN 
               
               
                 316 
                 347 
                 337 
                 GFQVYDLYKQIFNIYDPSLTFLALLRDVIPMP 
               
               
                 23 
                 42 
                 27 
                 GLAAVKALSLEPVNFSCIDL 
               
               
                 350 
                 367 
                 357 
                 ESQAALIARVYSGRYKLP 
               
               
                 442 
                 452 
                 448 
                 LKNVVEHVKRL 
               
               
                 261 
                 270 
                 267 
                 DGFCKHIGLI 
               
               
                 413 
                 422 
                 419 
                 LHTPGLVAPI 
               
               
                 172 
                 183 
                 178 
                 KLRYDAVIIANG 
               
               
                 121 
                 135 
                 125 
                 RSQVLEYIDDYIKSI 
               
               
                 186 
                 196 
                 191 
                 SNPYIPDVPGL 
               
               
                 12 
                 19 
                 14 
                 KRIAVIGG 
               
               
                 57 
                 72 
                 64 
                 GDKSLVKPEIPSLSPS 
               
               
                 106 
                 113 
                 109 
                 YSGVAFPA 
               
               
                 375 
                 380 
                 378 
                 YYQLEL 
               
               
                 97 
                 104 
                 103 
                 TNIVHQIM 
               
               
                 85 
                 93 
                 89 
                 DEYFSAIYE 
               
               
                 209 
                 216 
                 210 
                 HSKYYESP 
               
               
                 162 
                 168 
                 163 
                 IEDVIKK 
               
               
                 137 
                 143 
                 137 
                 KDTVNIS 
               
               
                   
               
            
           
           
               
               
            
               
                 26. IPF1428 
                   
               
               
                 MSPDNEPQPPNEDELLNNILPSYHMFQSTVSKNLTPTNENYSIDPPTYEMTPITSETPSLLTFSRMQSPVDE 
               
               
                   
               
               
                 RLETDNYFPQSDNDSVTYNQESEDMWKNSILANADKLPNLTHKKNSMSECLQIDIQVTEKVCQSGIKPIFMD 
               
               
                   
               
               
                 PSNREFKQGDYLHGYVTIRNTSDQPIPFDMVYVVFEGTFTTLDTSSGTISTEMPALRFKFLTMLDLFASWSY 
               
               
                   
               
               
                 ANIDRLITDNGDPHDWCNGETDPYDNTLLSIDVKRLFQPNVTYKRFFTFKIPDKLLDSTCDQYNLPTHTEIP 
               
               
                   
               
               
                 PTLGIDRNSFPPSFLLANQHLIVKDLSFSDSCLAYRIDARVIGKASDYKYKVDKDQYVVSKEASCPIRVVPT 
               
               
                   
               
               
                 PNLEMEYNFQQLKQEAELYYRAFVDSVMVKIEYGNELLNNKPGYSNTSRPNLSPMMSNDSVKLRQLYDVADD 
               
               
                   
               
               
                 TFKTNLRSGKSMRDEDYYQCLIPFKKKSITGSSKYLGIISLSTIKEHYKIRYTPPTRFGKAPPPNDTELLIP 
               
               
                   
               
               
                 LELNYFTESSTPLKNLPEIKAIDVEVVALSIRSKKHPIPIEFTTDMLFAEKEIDIKKSQPANFNSLVVARFS 
               
               
                   
               
               
                 NYLNEFHKLIKGVGNEALRLETKLYQDVKCLASLKTKYINLPISNLVFETTSQNGIGTTTEVKSLQWQEEQS 
               
               
                   
               
               
                 EKGKLFTKKFAVRMNLNNCSSKSNDNSSKGLDRITLVPSFQTCFASRLYYIKMTVRLNHGDSLLVNVPLNIH 
               
               
                   
               
               
                 RY* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 YKIRYTPPTRFGKAPP 
                 480 
                 0.96 
               
               
                 2 
                 ARVIGKASDYKYKVDK 
                 327 
                 0.94 
               
               
                 2 
                 CQSGIKPIFMDPSNRE 
                 134 
                 0.94 
               
               
                 3 
                 TRFGKAPPPNDTELLI 
                 488 
                 0.93 
               
               
                 4 
                 LRSGKSMRDEDYYQCL 
                 438 
                 0.91 
               
               
                 4 
                 DWCNGETDPYDNTLLS 
                 231 
                 0.91 
               
               
                 4 
                 DRLITDNGDPHDWCNG 
                 220 
                 0.91 
               
               
                 5 
                 LFTKKFAVRMNLNNCS 
                 653 
                 0.90 
               
               
                 5 
                 QLKQEAELYYRAFVDS 
                 371 
                 0.90 
               
               
                 5 
                 HGYVTIRNTSDQPIPF 
                 157 
                 0.90 
               
               
                 6 
                 VVSKEASCPIRVVPTP 
                 346 
                 0.89 
               
               
                 6 
                 QSTVSKNLTPTNENYS 
                 27 
                 0.89 
               
               
                 7 
                 TNENYSIDPPTYEMTP 
                 37 
                 0.88 
               
               
                 7 
                 ASDYKYKVDKDQYVVS 
                 333 
                 0.88 
               
               
                 8 
                 FQTCFASRLYYIKMTV 
                 688 
                 0.87 
               
               
                 8 
                 TSSGTISTEMPALRFK 
                 188 
                 0.87 
               
               
                 9 
                 FSRMQSPVDERLETDN 
                 63 
                 0.86 
               
               
                 9 
                 SQNGIGTTTEVKSLQW 
                 628 
                 0.86 
               
               
                 10 
                 EDMWKNSILANADKLP 
                 95 
                 0.85 
               
               
                 10 
                 DERLETDNYFPQSDND 
                 71 
                 0.85 
               
               
                 10 
                 TSETPSLLTFSRMQSP 
                 54 
                 0.85 
               
               
                 10 
                 ALSIRSKKHPIPIEFT 
                 532 
                 0.85 
               
               
                 10 
                 THTEIPPTLGIDRNSF 
                 283 
                 0.85 
               
               
                 11 
                 NNKPGYSNTSRPNLSP 
                 399 
                 0.84 
               
               
                 12 
                 DNEPQPPNEDELLNNI 
                 4 
                 0.83 
               
               
                 13 
                 VDSVMVKIEYGNELLN 
                 384 
                 0.82 
               
               
                 13 
                 DSTCDQYNLPTHTEIP 
                 273 
                 0.82 
               
               
                 14 
                 PQSDNDSVTYNQESED 
                 81 
                 0.79 
               
               
                 15 
                 SNDNSSKGLDRITLVP 
                 671 
                 0.77 
               
               
                 15 
                 TKYINLPISNLVFETT 
                 612 
                 0.77 
               
               
                 15 
                 EKEIDIKKSQPANFNS 
                 554 
                 0.77 
               
               
                 15 
                 PTYEMTPITSETPSLL 
                 46 
                 0.77 
               
               
                 15 
                 CLQIDIQVTEKVCQSG 
                 122 
                 0.77 
               
               
                 16 
                 KGVGNEALRLETKLYQ 
                 587 
                 0.76 
               
               
                 16 
                 TDMLFAEKEIDIKKSQ 
                 548 
                 0.76 
               
               
                 16 
                 PTLGIDRNSFPPSFLL 
                 289 
                 0.76 
               
               
                 17 
                 SCPIRVVPTPNLEMEY 
                 352 
                 0.75 
               
               
                 17 
                 MVYVVFEGTFTTLDTS 
                 174 
                 0.75 
               
               
                 17 
                 KNSMSECLQIDIQVTE 
                 116 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 708 
                 719 
                 714 
                 GDSLLVNVPLNI 
               
               
                 335 
                 361 
                 356 
                 DYKYKVDKDQYVVSKEASCPIRVVPTP 
               
               
                 522 
                 545 
                 531 
                 EIKAIDVEVVALSIRSKKHPIPIE 
               
               
                 601 
                 626 
                 607 
                 YQDVKCLASLKTKYINLPISNLVFET 
               
               
                 449 
                 458 
                 452 
                 YYQCLIPFKK 
               
               
                 168 
                 181 
                 178 
                 QPIPFDMVYVVFEG 
               
               
                 500 
                 508 
                 504 
                 ELLIPLELN 
               
               
                 567 
                 576 
                 572 
                 FNSLVVARFS 
               
               
                 375 
                 392 
                 381 
                 EAELYYRAFVDSVMVKIE 
               
               
                 299 
                 333 
                 311 
                 PPSFLLANQHLIVKDLSFSDSCLAYRIDARVIGKA 
               
               
                 681 
                 702 
                 688 
                 RITLVPSFQTCFASRLYYIKMT 
               
               
                 120 
                 141 
                 132 
                 SECLQIDIQVTEKVCQSGIKPI 
               
               
                 420 
                 432 
                 424 
                 SVKLRQLYDVADD 
               
               
                 464 
                 485 
                 470 
                 SSKYLGIISLSTIKEHYKIRYT 
               
               
                 242 
                 252 
                 247 
                 NTLLSIDVKRL 
               
               
                 153 
                 163 
                 158 
                 GDYLHGYVTIR 
               
               
                 268 
                 282 
                 273 
                 PDKLLDSTCDQYNLP 
               
               
                 580 
                 588 
                 586 
                 NEFHKLIKG 
               
               
                 57 
                 63 
                 61 
                 TPSLLTF 
               
               
                 17 
                 33 
                 22 
                 NNILPSYHMFQSTVSKN 
               
               
                 254 
                 260 
                 255 
                 QPNVTYK 
               
               
                 205 
                 214 
                 213 
                 LTMLDLFASW 
               
               
                 284 
                 291 
                 290 
                 HTEIPPTL 
               
               
                 67 
                 72 
                 71 
                 QSPVDE 
               
               
                   
               
            
           
           
               
               
            
               
                 27. MEP2 
                   
               
               
                 MSGNFTGTGTGGDVFKVDLNEQFDRADMVWIGTASVLVWIMIPGVGLLYSGISRKKHALSLMWAALMAACVA 
               
               
                   
               
               
                 AFQWFWWGYSLVFAHNGSVFLGTLQNFCLKDVLGAPSIVKTVPDILFCLYQGMFAAVTAILMAGAGCERARL 
               
               
                   
               
               
                 GPMMVFLFIWLTVVYCPIAYWTWGGNGWLVSLGALDFAGGGPVHENSGFAALAYSLWLGKRHDPVAKGKVPK 
               
               
                   
               
               
                 YKPHSVSSIVMGTIFLWFGWYGFNGGSTGNSSMRSWYACVNTNLAAATGGLTWMLVDWFRTGGKWSTVGLCM 
               
               
                   
               
               
                 GAIAGLVGITPAAGYVPVYTSVIFGIVPAIICNFAVDLKDLLQIDDGMDVWALHGVGGFVGNFMTGLFAADY 
               
               
                   
               
               
                 VAMIDGTEIDGGWMNHHWKQLGYQLAGSCAVAAWSFTVTSIILLAMDRIPFLRIRLHEDEEMLGTDLAQIGE 
               
               
                   
               
               
                 YAYYADDDPETNPYVLEPIRSTTISQPLPHIDGVADGSSNNDSGEAKN* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 TGTGTGGDVFKVDLNE 
                 6 
                 0.98 
               
               
                 2 
                 IGEYAYYADDDPETNP 
                 430 
                 0.92 
               
               
                 3 
                 DGTEIDGGWMNHHWKQ 
                 365 
                 0.91 
               
               
                 4 
                 STTISQPLPHIDGVAD 
                 453 
                 0.89 
               
               
                 4 
                 GLTWMLVDWFRTGGKW 
                 266 
                 0.89 
               
               
                 5 
                 AIAGLVGITPAAGYVP 
                 290 
                 0.88 
               
               
                 5 
                 VGLCMGAIAGLVGITP 
                 284 
                 0.88 
               
               
                 6 
                 HIDGVADGSSNNDSGE 
                 462 
                 0.87 
               
               
                 6 
                 DWFRTGGKWSTVGLCM 
                 273 
                 0.87 
               
               
                 6 
                 DFAGGGPVHENSGFAA 
                 180 
                 0.87 
               
               
                 6 
                 AILMAGAGCERARLGP 
                 131 
                 0.87 
               
               
                 7 
                 LWFGWYGFNGGSTGNS 
                 232 
                 0.86 
               
               
                 8 
                 IVMGTIFLWFGWYGFN 
                 225 
                 0.84 
               
               
                 8 
                 YCPIAYWTWGGNGWLV 
                 159 
                 0.84 
               
               
                 8 
                 FLFIWLTVVYCPIAYW 
                 150 
                 0.84 
               
               
                 9 
                 GGSTGNSSMRSWYACV 
                 241 
                 0.83 
               
               
                 9 
                 LWLGKRHDPVAKGKVP 
                 200 
                 0.83 
               
               
                 10 
                 WFWWGYSLVFAHNGSV 
                 76 
                 0.82 
               
               
                 10 
                 LVWIMIPGVGLLYSGI 
                 37 
                 0.82 
               
               
                 11 
                 YTSVIFGIVPAIICNF 
                 307 
                 0.81 
               
               
                 11 
                 GITPAAGYVPVYTSVI 
                 296 
                 0.81 
               
               
                 12 
                 NPYVLEPIRSTTISQP 
                 444 
                 0.80 
               
               
                 12 
                 FAALAYSLWLGKRHDP 
                 193 
                 0.80 
               
               
                 13 
                 CVAAFQWFWWGYSLVF 
                 70 
                 0.79 
               
               
                 14 
                 GWLVSLGALDFAGGGP 
                 171 
                 0.78 
               
               
                 14 
                 AGCERARLGPMMVFLF 
                 137 
                 0.78 
               
               
                 15 
                 FVGNFMTGLFAADYVA 
                 347 
                 0.77 
               
               
                 15 
                 MVWIGTASVLVWIMIP 
                 28 
                 0.77 
               
               
                 15 
                 GKVPKYKPHSVSSIVM 
                 212 
                 0.77 
               
               
                 16 
                 HWKQLGYQLAGSCAVA 
                 377 
                 0.76 
               
               
                 16 
                 GAPSIVKTVPDILFCL 
                 106 
                 0.76 
               
               
                 17 
                 LGTLQNFCLKDVLGAP 
                 93 
                 0.75 
               
               
                 17 
                 MDVWALHGVGGFVGNF 
                 336 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 146 
                 164 
                 160 
                 PMMVFLFIWLTVVYCPIAY 
               
               
                 283 
                 332 
                 317 
                 TVGLCMGAIAGLVGITPAAGYVPVYTSVIFGIVPAIICN 
               
               
                   
                   
                   
                 FAVDLKDLLQI 
               
               
                 80 
                 136 
                 120 
                 GYSLVFAHNGSVFLGTLQNFCLKDVLGAPSIVKTVPDIL 
               
               
                   
                   
                   
                 FCLYQGMFAAVTAILMAG 
               
               
                 66 
                 75 
                 71 
                 LMAACVAAFQ 
               
               
                 31 
                 52 
                 37 
                 IGTASVLVWIMIPGVGLLYSGI 
               
               
                 378 
                 407 
                 401 
                 WKQLGYQLAGSCAVAAWSFTVTSIILLAMD 
               
               
                 172 
                 181 
                 176 
                 WLVSLGALDF 
               
               
                 206 
                 229 
                 223 
                 HDPVAKGKVPKYKPHSVSSIVMGT 
               
               
                 338 
                 347 
                 341 
                 VWALHGVGGF 
               
               
                 444 
                 451 
                 448 
                 NPYVLEPI 
               
               
                 193 
                 203 
                 199 
                 FAALAYSLWLG 
               
               
                 354 
                 364 
                 358 
                 GLFAADYVAMI 
               
               
                 252 
                 259 
                 253 
                 WYACVNTN 
               
               
                 14 
                 20 
                 16 
                 VFKVDLN 
               
               
                 456 
                 466 
                 463 
                 ISQPLPHIDGV 
               
               
                 409 
                 415 
                 414 
                 IPFLRIR 
               
               
                 55 
                 64 
                 58 
                 KKHALSLMWA 
               
               
                 425 
                 438 
                 433 
                 TDLAQIGEYAYYAD 
               
               
                 269 
                 274 
                 269 
                 WMLVDW 
               
               
                   
               
            
           
           
               
               
            
               
                 28. PTH1 
                   
               
               
                 MITKCYVQVFRYRRVCHNTKYSFNSVVSIKWLHSAGSSLSQANSSKTSQSSLTSSGFLYYEDPHRYNGSDVS 
               
               
                   
               
               
                 ANASETTSTSTAKPVIHSATPYSDKYYQPIISQGAKGFDKLIIPVGFCADNQTVSLEEDKESPIQQDQLQEI 
               
               
                   
               
               
                 VNSFDAPIDVSIGYGSGILPQDGYDKDKSTSNNTANDSKQLDFMFLVKDCGKFHQENLKQNRDHYSIKSLRL 
               
               
                   
               
               
                 IKKVQGTNGMYFNPFIKINEKLVKYGVISSKSALMDLSEWHSLYFAGRLQKPVNFITTNDPRVKFLNQYNLK 
               
               
                   
               
               
                 NAMTIAIFLIDGEGNSRQATFNERQLYEQITKLSYLGDFRMYIGGENPNKSKNIVAKQFHHFKKLYEPILQY 
               
               
                   
               
               
                 FIHKNFLIIVDNDPVNRTFKPNLNVNNRIKLITGLPLKFRQQLYGRYYEKSIKEIVIDDHLSQNLTKIISRT 
               
               
                   
               
               
                 IIISSITQAIRGLLSAGLFNSIKYAVAKQIKFWTSKK* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 DGYDKDKSTSNNTAND 
                 166 
                 0.95 
               
               
                 2 
                 PVIHSATPYSDKYYQP 
                 86 
                 0.92 
               
               
                 3 
                 GFLYYEDPHRYNGSDV 
                 56 
                 0.91 
               
               
                 4 
                 FRMYIGGENPNKSKNI 
                 327 
                 0.90 
               
               
                 4 
                 AGRLQKPVNFITTNDP 
                 262 
                 0.90 
               
               
                 4 
                 YGSGILPQDGYDKDKS 
                 158 
                 0.90 
               
               
                 5 
                 NFLIIVDNDPVNRTFK 
                 365 
                 0.85 
               
               
                 6 
                 YQPIISQGAKGFDKLI 
                 99 
                 0.84 
               
               
                 6 
                 NDPVNRTFKPNLNVNN 
                 372 
                 0.84 
               
               
                 6 
                 VNFITTNDPRVKFLNQ 
                 269 
                 0.84 
               
               
                 6 
                 RVCHNTKYSFNSVVSI 
                 14 
                 0.84 
               
               
                 7 
                 KCYVQVFRYRRVCHNT 
                 4 
                 0.82 
               
               
                 7 
                 QGTNGMYFNPFIKINE 
                 221 
                 0.82 
               
               
                 7 
                 DAPIDVSIGYGSGILP 
                 149 
                 0.82 
               
               
                 7 
                 DQLQEIVNSFDAPIDV 
                 139 
                 0.82 
               
               
                 8 
                 TTSTSTAKPVIHSATP 
                 78 
                 0.81 
               
               
                 9 
                 HYSIKSLRLIKKVQGT 
                 208 
                 0.80 
               
               
                 10 
                 GFCADNQTVSLEEDKE 
                 118 
                 0.79 
               
               
                 11 
                 NGSDVSANASETTSTS 
                 67 
                 0.78 
               
               
                 11 
                 SQSSLTSSGFLYYEDP 
                 48 
                 0.78 
               
               
                 11 
                 TQAIRGLLSAGLFNSI 
                 439 
                 0.78 
               
               
                 11 
                 EIVIDDHLSQNLTKII 
                 414 
                 0.78 
               
               
                 11 
                 VVSIKWLHSAGSSLSQ 
                 26 
                 0.78 
               
               
                 12 
                 LSEWHSLYFAGRLQKP 
                 253 
                 0.77 
               
               
                 12 
                 FDKLIIPVGFCADNQT 
                 110 
                 0.77 
               
               
                 13 
                 KFRQQLYGRYYEKSIK 
                 398 
                 0.76 
               
               
                 14 
                 TIAIFLIDGEGNSRQA 
                 292 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 4 
                 19 
                 7 
                 KCYVQVFRYRRVCHNT 
               
               
                 235 
                 248 
                 241 
                 NEKLVKYGVISSKS 
               
               
                 110 
                 129 
                 117 
                 FDKLIIPVGFCADNQTVSLE 
               
               
                 23 
                 42 
                 29 
                 FNSVVSIKWLHSAGSSLSQA 
               
               
                 341 
                 373 
                 360 
                 NIVAKQFHHFKKLYEPILQYFIHKNFLIIVDND 
               
               
                 186 
                 197 
                 192 
                 DFMFLVKDCGKF 
               
               
                 430 
                 462 
                 448 
                 SRTIIISSITQAIRGLLSAGLFNSIKYAVAKQI 
               
               
                 413 
                 420 
                 418 
                 KEIVIDDH 
               
               
                 293 
                 298 
                 295 
                 IAIFLI 
               
               
                 209 
                 220 
                 217 
                 YSIKSLRLIKKV 
               
               
                 390 
                 407 
                 394 
                 KLITGLPLKFRQQLYGRY 
               
               
                 84 
                 105 
                 101 
                 AKPVIHSATPYSDKYYQPIISQ 
               
               
                 137 
                 157 
                 153 
                 QQDQLQEIVNSFDAPIDVSIG 
               
               
                 314 
                 325 
                 321 
                 LYEQITKLSYLG 
               
               
                 256 
                 271 
                 259 
                 WHSLYFAGRLQKPVNF 
               
               
                 49 
                 63 
                 57 
                 QSSLTSSGFLYYEDP 
               
               
                 159 
                 166 
                 161 
                 GSGILPQD 
               
               
                 422 
                 428 
                 423 
                 SQNLTKI 
               
               
                   
               
            
           
           
               
               
            
               
                 29. ENA22 
                   
               
               
                 MSSTKENSNYASGDTKERANSDLSESDRSTPPRDPNSTFQAYRLTIDEVAQEFNTSIVDGLGAHDAENRIQA 
               
               
                   
               
               
                 YGPNNLGEGDKISYPKILAHQVFNAMILVLIISMIIALAIKDWISGGVIAFVVFLNISVGFVQEVKAEKTMG 
               
               
                   
               
               
                 SLKNLSSPTARVTRNGDDFTIPAEEVVPGDIVHIKVGDTVPADLRLFDCMNLETDEALLTGESLPVAKNFEV 
               
               
                   
               
               
                 VYTDYSVPVPVGDRLNLVYSSSIVSKGRGSGIVFATGLNTEIGAIAQSLKGNSGLIRRVDKSNDRKPQKREY 
               
               
                   
               
               
                 GQAAAGTIYDVVGNILGVTVGTPLQRKLSWLAIFLFCVAVVFAIIVMGSQKFHVNKEVAIYAICVALSMIPS 
               
               
                   
               
               
                 ALILVLTITMAVGAQVMVTKNVIVRKFDSLEALGGINDICSDKTGTLTQGKMIAKKVWLPNIGTLDVQNSNE 
               
               
                   
               
               
                 PYNPTVGDVRFAPYSPKFVKETDEEIDFNKPYPDPMPESMHKWLMTATLANIATVNQTKDEDTGELLWKAHG 
               
               
                   
               
               
                 DATEIAIQVFTTRLNYGRESIAQEYEHLAEFPFDSSIKRMSAIYKKDGETRVYTKGAVERLLGLCDYWYGER 
               
               
                   
               
               
                 TEDDYDSQTLVKLTEDDAKLIEENMAALSSQGLRVLAFATKELGDADMNDREQVESHLIFQGLIGIYDPPRE 
               
               
                   
               
               
                 ESAQSVKSCHKAGINVHMLTGDHPGTAKAIAQEVGILPHNLYHYSEDVVKVMVMSANDFDALTDDEIDNLPV 
               
               
                   
               
               
                 LPLVIARCAPKTKVRMIDALHRRKKFAAMTGDGVNDSPSLKKADVGIAMGLNGSDVAKDASDIVLTDDNFAS 
               
               
                   
               
               
                 ILNAIEEGRRMSANIQKFVLQLLAENVAQAFYLMIGLAFLDETGYSVFPLSPVEVLWILVVTSTFPAIGLAQ 
               
               
                   
               
               
                 NAASDDILEKPPNNTIFTWEVIIDMFAYGVIMAATCLLSFVIVVYGAGNGDLGIDCNATNADKDLCSLVFEG 
               
               
                   
               
               
                 RSTAFASMTWQALILAWECLDPKKSLLLIPFSELWANQFLFWSIVGGFVTVFPVIYIPVINTKVFLHKSITW 
               
               
                   
               
               
                 EWGVAVGTTALFLLGAEAWKWGKRVFARSSKAKNPEYELERNDPFQRYASFSRANTMVV* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 KVMVMSANDFDALTDD 
                 698 
                 0.96 
               
               
                 2 
                 QGLIGIYDPPREESAQ 
                 637 
                 0.94 
               
               
                 2 
                 SESDRSTPPRDPNSTF 
                 24 
                 0.94 
               
               
                 3 
                 MLTGDHPGTAKAIAQE 
                 666 
                 0.93 
               
               
                 4 
                 AGTIYDVVGNILGVTV 
                 293 
                 0.92 
               
               
                 5 
                 LNAIEEGRRMSANIQK 
                 794 
                 0.91 
               
               
                 5 
                 VRMIDALHRRKKFAAM 
                 734 
                 0.91 
               
               
                 6 
                 SMTWQALILAWECLDP 
                 943 
                 0.90 
               
               
                 6 
                 KWLMTATLANIATVNQ 
                 474 
                 0.90 
               
               
                 7 
                 SSKAKNPEYELERNDP 
                 1037 
                 0.89 
               
               
                 8 
                 EVIIDMFAYGVIMAAT 
                 884 
                 0.88 
               
               
                 8 
                 DATEIAIQVFTTRLNY 
                 505 
                 0.88 
               
               
                 8 
                 SKGRGSGIVFATGLNT 
                 241 
                 0.88 
               
               
                 8 
                 YASGDTKERANSDLSE 
                 10 
                 0.88 
               
               
                 9 
                 YGAGNGDLGIDCNATN 
                 909 
                 0.87 
               
               
                 9 
                 DYWYGERTEDDYDSQT 
                 570 
                 0.87 
               
               
                 9 
                 MSAIYKKDGETRVYTK 
                 544 
                 0.87 
               
               
                 9 
                 HIKVGDTVPADLRLFD 
                 177 
                 0.87 
               
               
                 9 
                 SITWEWGVAVGTTALF 
                 1005 
                 0.87 
               
               
                 10 
                 YPKILAHQVFNAMILV 
                 86 
                 0.86 
               
               
                 10 
                 VKETDEEIDFNKPYPD 
                 451 
                 0.86 
               
               
                 11 
                 NGSDVAKDASDIVLTD 
                 772 
                 0.85 
               
               
                 11 
                 AGINVHMLTGDHPGTA 
                 660 
                 0.85 
               
               
                 11 
                 SNEPYNPTVGDVRFAP 
                 430 
                 0.85 
               
               
                 11 
                 SGLIRRVDKSNDRKPQ 
                 269 
                 0.85 
               
               
                 11 
                 VQEVKAEKTMGSLKNL 
                 134 
                 0.85 
               
               
                 12 
                 RRKKFAAMTGDGVNDS 
                 742 
                 0.84 
               
               
                 12 
                 GDVRFAPYSPKFVKET 
                 439 
                 0.84 
               
               
                 12 
                 VLTITMAVGAQVMVTK 
                 365 
                 0.84 
               
               
                 12 
                 LSSPTARVTRNGDDFT 
                 149 
                 0.84 
               
               
                 13 
                 MPESMHKWLMTATLAN 
                 468 
                 0.83 
               
               
                 13 
                 IGAIAQSLKGNSGLIR 
                 258 
                 0.83 
               
               
                 13 
                 EVVYTDYSVPVPVGDR 
                 215 
                 0.83 
               
               
                 13 
                 AEAWKWGKRVFARSSK 
                 1024 
                 0.83 
               
               
                 14 
                 LILAWECLDPKKSLLL 
                 949 
                 0.82 
               
               
                 14 
                 TPPRDPNSTFQAYRLT 
                 30 
                 0.82 
               
               
                 15 
                 VGIAMGLNGSDVAKDA 
                 765 
                 0.81 
               
               
                 15 
                 TGDGVNDSPSLKKADV 
                 750 
                 0.81 
               
               
                 15 
                 ENRIQAYGPNNLGEGD 
                 67 
                 0.81 
               
               
                 15 
                 YGRESIAQEYEHLAEF 
                 520 
                 0.81 
               
               
                 15 
                 ELLWKAHGDATEIAIQ 
                 497 
                 0.81 
               
               
                 15 
                 MGSLKNLSSPTARVTR 
                 143 
                 0.81 
               
               
                 16 
                 DGLGAHDAENRIQAYG 
                 59 
                 0.80 
               
               
                 16 
                 ALGGINDICSDKTGTL 
                 392 
                 0.80 
               
               
                 16 
                 IVRKFDSLEALGGIND 
                 383 
                 0.80 
               
               
                 17 
                 YGVIMAATCLLSFVIV 
                 892 
                 0.79 
               
               
                 17 
                 AIIVMGSQKFHVNKEV 
                 331 
                 0.79 
               
               
                 17 
                 DWISGGVIAFVVFLNI 
                 114 
                 0.79 
               
               
                 18 
                 EVAIYAICVALSMIPS 
                 345 
                 0.78 
               
               
                 18 
                 ERANSDLSESDRSTPP 
                 17 
                 0.78 
               
               
                 19 
                 ASDIVLTDDNFASILN 
                 780 
                 0.77 
               
               
                 19 
                 GVTVGTPLQRKLSWLA 
                 305 
                 0.77 
               
               
                 20 
                 GFVTVFPVIYIPVINT 
                 983 
                 0.76 
               
               
                 20 
                 IGLAQNAASDDILEKP 
                 860 
                 0.76 
               
               
                 20 
                 TGYSVFPLSPVEVLWI 
                 835 
                 0.76 
               
               
                 20 
                 KELGDADMNDREQVES 
                 617 
                 0.76 
               
               
                 20 
                 SQTLVKLTEDDAKLIE 
                 583 
                 0.76 
               
               
                 20 
                 VWLPNIGTLDVQNSNE 
                 417 
                 0.76 
               
               
                 20 
                 CSDKTGTLTQGKMIAK 
                 400 
                 0.76 
               
               
                 20 
                 STFQAYRLTIDEVAQE 
                 37 
                 0.76 
               
               
                 21 
                 TAKAIAQEVGILPHNL 
                 674 
                 0.75 
               
               
                 21 
                 ESAQSVKSCHKAGINV 
                 649 
                 0.75 
               
               
                 21 
                 GETRVYTKGAVERLLG 
                 552 
                 0.75 
               
               
                 21 
                 TRNGDDFTIPAEEVVP 
                 157 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 313 
                 337 
                 326 
                 QRKLSWLAIFLFCVAVVFAIIVMGS 
               
               
                 836 
                 865 
                 850 
                 GYSVFPLSPVEVLWILVVTSTFPAIGLAQN 
               
               
                 882 
                 911 
                 905 
                 TWEVIIDMFAYGVIMAATCLLSFVIVVYGA 
               
               
                 717 
                 732 
                 721 
                 NLPVLPLVIARCAPKT 
               
               
                 117 
                 138 
                 123 
                 SGGVIAFVVFLNISVGFVQEVK 
               
               
                 339 
                 387 
                 352 
                 KFHVNKEVAIYAICVALSMIPSALILVLTITMAVGAQVMVT 
               
               
                   
                   
                   
                 KNVIVRKF 
               
               
                 199 
                 242 
                 224 
                 DEALLTGESLPVAKNFEVVYTDYSVPVPVGDRLNLVYSSSI 
               
               
                   
                   
                   
                 VSK 
               
               
                 973 
                 1005 
                 993 
                 NQFLFWSIVGGFVTVFPVIYIPVINTKVFLHKS 
               
               
                 84 
                 114 
                 102 
                 ISYPKILAHQVFNAMILVLIISMIIALAIKD 
               
               
                 807 
                 832 
                 813 
                 IQKFVLQLLAENVAQAFYLMIGLAFL 
               
               
                 927 
                 935 
                 931 
                 KDLCSLVFE 
               
               
                 674 
                 702 
                 698 
                 TAKAIAQEVGILPHNLYHYSEDVVKVMVM 
               
               
                 167 
                 194 
                 173 
                 AEEVVPGDIVHIKVGDTVPADLRLFDCM 
               
               
                 947 
                 969 
                 964 
                 QALILAWECLDPKKSLLLIPFSE 
               
               
                 562 
                 572 
                 568 
                 VERLLGLCDYW 
               
               
                 603 
                 616 
                 612 
                 ALSSQGLRVLAFAT 
               
               
                 651 
                 667 
                 655 
                 AQSVKSCHKAGINVHML 
               
               
                 630 
                 645 
                 633 
                 VESHLIFQGLIGIYDP 
               
               
                 1011 
                 1024 
                 1021 
                 GVAVGTTALFLLGA 
               
               
                 293 
                 311 
                 306 
                 AGTIYDVVGNILGVTVGTP 
               
               
                 508 
                 516 
                 512 
                 EIAIQVFTT 
               
               
                 583 
                 590 
                 586 
                 SQTLVKLT 
               
               
                 246 
                 252 
                 251 
                 SGIVFAT 
               
               
                 435 
                 451 
                 448 
                 NPTVGDVRFAPYSPKFV 
               
               
                 781 
                 787 
                 783 
                 SDIVLTD 
               
               
                 414 
                 420 
                 416 
                 AKKVWLP 
               
               
                 481 
                 487 
                 484 
                 LANIATV 
               
               
                 526 
                 536 
                 534 
                 AQEYEHLAEFP 
               
               
                 259 
                 264 
                 263 
                 GAIAQS 
               
               
                 39 
                 52 
                 47 
                 FQAYRLTIDEVAQE 
               
               
                 791 
                 796 
                 794 
                 ASILNA 
               
               
                 759 
                 768 
                 762 
                 SLKKADVGIA 
               
               
                 1032 
                 1037 
                 1036 
                 RVFARS 
               
               
                 1054 
                 1059 
                 1056 
                 QRYASF 
               
               
                 397 
                 402 
                 398 
                 NDICSD 
               
               
                   
               
            
           
           
               
               
            
               
                 30. MDL1 
                   
               
               
                 MIGMNRLIFSKAFTSSCKSMGKVPFTKSITRANTRYFKPTSILQQIRFNSKSSTTPNTEANSNGSTNSQSDT 
               
               
                   
               
               
                 KKPRPKLTSEIFKLLRLAKPESKLIFFALICLVTTSATTMTLPLMIGKIIDTTKKDDDDDKGKDNDDKDDTQ 
               
               
                   
               
               
                 PSDKLIFGLPQPQFYSALGVLFIVSASTNFGRIYLLRSVGERLVARLRSRLFSKILAQDAYFFDLGPSKTGM 
               
               
                   
               
               
                 KTGDLISRIASDTQIISKSLSMNISDGIRAIISGCVGLSMMCYVSWKLSLCMSLIFPPLITMSWFYGRKIKA 
               
               
                   
               
               
                 LSKLIQENIGDMTKVTEEKLNGVKVIQTFSQQQSVVHSYNQEIKNIFNSSMREAKLAGFFYSTNGFIGNVTM 
               
               
                   
               
               
                 IGLLIMGTKLIGAGELTVGDLSSFMMYAVYTGTSVFGLGNFYTELMKGIGAAERVFELVEYQPRISNHLGKK 
               
               
                   
               
               
                 VDELNGDIEFKGIDFTYPSRPESGIFKDLNLHIKQGENVCLVGPSGSGKSTVSQLLLRFYDPEKGTIQIGDD 
               
               
                   
               
               
                 VITDLNLNHYRSKLGYVQQEPLLFSGTIKENILFGKEDATDEEINNALNLSYASNFVRHLPDGLDTKIGASN 
               
               
                   
               
               
                 STQLSGGQKQRVSLARTLIRDPKILILDEATSALDSVSEEIVMSNLIQLNKNRGVTLISIAHRLSTIKNSDR 
               
               
                   
               
               
                 IIVFNQDGQIVEDGKFNELHNDPNSQFNKLLKSHSLE* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 TNSQSDTKKPRPKLTS 
                 66 
                 0.94 
               
               
                 1 
                 SGTIKENILFGKEDAT 
                 529 
                 0.94 
               
               
                 2 
                 KGTIQIGDDVITDLNL 
                 496 
                 0.92 
               
               
                 2 
                 TTKKDDDDDKGKDNDD 
                 124 
                 0.92 
               
               
                 3 
                 TKSITRANTRYFKPTS 
                 26 
                 0.91 
               
               
                 4 
                 DGQIVEDGKFNELHND 
                 655 
                 0.90 
               
               
                 4 
                 SKLIQENIGDMTKVTE 
                 290 
                 0.90 
               
               
                 5 
                 SKSSTTPNTEANSNGS 
                 50 
                 0.89 
               
               
                 5 
                 IGKIIDTTKKDDDDDK 
                 118 
                 0.89 
               
               
                 6 
                 DFTYPSRPESGIFKDL 
                 446 
                 0.88 
               
               
                 6 
                 SSMREAKLAGFFYSTN 
                 337 
                 0.88 
               
               
                 7 
                 AGFFYSTNGFIGNVTM 
                 345 
                 0.87 
               
               
                 7 
                 TQIISKSLSMNISDGI 
                 229 
                 0.87 
               
               
                 8 
                 FGKEDATDEEINNALN 
                 538 
                 0.86 
               
               
                 8 
                 YVSWKLSLCMSLIFPP 
                 259 
                 0.86 
               
               
                 9 
                 TKLIGAGELTVGDLSS 
                 368 
                 0.85 
               
               
                 9 
                 TMSWFYGRKIKALSKL 
                 277 
                 0.85 
               
               
                 10 
                 MMYAVYTGTSVFGLGN 
                 385 
                 0.84 
               
               
                 10 
                 FSKILAQDAYFFDLGP 
                 196 
                 0.84 
               
               
                 10 
                 SCKSMGKVPFTKSITR 
                 16 
                 0.84 
               
               
                 11 
                 HRLSTIKNSDRIIVFN 
                 638 
                 0.83 
               
               
                 12 
                 TLISIAHRLSTIKNSD 
                 632 
                 0.82 
               
               
                 12 
                 AERVFELVEYQPRISN 
                 412 
                 0.82 
               
               
                 13 
                 SDGIRAIISGCVGLSM 
                 241 
                 0.81 
               
               
                 14 
                 GLLIMGTKLIGAGELT 
                 362 
                 0.80 
               
               
                 15 
                 DSVSEEIVMSNLIQLN 
                 611 
                 0.79 
               
               
                 15 
                 PTSILQQIRFNSKSST 
                 39 
                 0.79 
               
               
                 15 
                 TKVTEEKLNGVKVIQT 
                 301 
                 0.79 
               
               
                 16 
                 GYVQQEPLLFSGTIKE 
                 519 
                 0.77 
               
               
                 17 
                 TEANSNGSTNSQSDTK 
                 58 
                 0.76 
               
               
                 17 
                 LMKGIGAAERVFELVE 
                 405 
                 0.76 
               
               
                 17 
                 TGMKTGDLISRIASDT 
                 214 
                 0.76 
               
               
                 18 
                 QSVVHSYNQEIKNIFN 
                 321 
                 0.75 
               
               
                 18 
                 IISGCVGLSMMCYVSW 
                 247 
                 0.75 
               
               
                 18 
                 FGRIYLLRSVGERLVA 
                 174 
                 0.75 
               
               
                 18 
                 DDKGKDNDDKDDTQPS 
                 131 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 80 
                 108 
                 102 
                 TSEIFKLLRLAKPESKLIFFALICLVTTS 
               
               
                 146 
                 171 
                 165 
                 SDKLIFGLPQPQFYSALGVLFIVSAS 
               
               
                 469 
                 477 
                 474 
                 ENVCLVGPS 
               
               
                 176 
                 210 
                 180 
                 RIYLLRSVGERLVARLRSRLFSKILAQDAYFFDLG 
               
               
                 310 
                 328 
                 324 
                 GVKVIQTFSQQQSVVHSYN 
               
               
                 482 
                 492 
                 486 
                 STVSQLLLRFY 
               
               
                 245 
                 279 
                 249 
                 RAIISGCVGLSMMCYVSWKLSLCMSLIFPPLITMS 
               
               
                 412 
                 424 
                 418 
                 AERVFELVEYQPR 
               
               
                 631 
                 641 
                 634 
                 VTLISIAHRLS 
               
               
                 514 
                 530 
                 524 
                 YRSKLGYVQQEPLLFSG 
               
               
                 676 
                 682 
                 681 
                 NKLLKSH 
               
               
                 586 
                 593 
                 591 
                 QRVSLART 
               
               
                 286 
                 292 
                 291 
                 IKALSKL 
               
               
                 596 
                 617 
                 600 
                 RDPKILILDEATSALDSVSEEI 
               
               
                 360 
                 368 
                 361 
                 MIGLLIMGT 
               
               
                 553 
                 567 
                 563 
                 NLSYASNFVRHLPDG 
               
               
                 386 
                 399 
                 392 
                 MYAVYTGTSVFGLG 
               
               
                 8 
                 18 
                 10 
                 IFSKAFTSSCK 
               
               
                 619 
                 625 
                 620 
                 MSNLIQL 
               
               
                 38 
                 46 
                 45 
                 KPTSILQQI 
               
               
                 375 
                 381 
                 379 
                 ELTVGDL 
               
               
                 20 
                 27 
                 26 
                 MGKVPFTK 
               
               
                 648 
                 654 
                 649 
                 RIIVFNQ 
               
               
                 228 
                 235 
                 233 
                 DTQIISKS 
               
               
                 460 
                 466 
                 464 
                 DLNLHIK 
               
               
                 113 
                 119 
                 117 
                 TLPLMIG 
               
               
                 656 
                 661 
                 657 
                 GQIVED 
               
               
                   
               
            
           
           
               
               
            
               
                 31. ALP1 
                   
               
               
                 MSVEYPNSVTSLDKKPQVDLENVIEDASTSSEHRVAQTENLNRSLGARTINLICLGGVIGTGIFLGMGKMLS 
               
               
                   
               
               
                 NAGPLGLLLNYLIMGSMIYFMMLSLGEMSVQYPISGSFAVYTKRFGSDSLAFATLFNYWLNDCVSVAADLVA 
               
               
                   
               
               
                 LQLVMQYWTNFHWYVISIIFWVFLLLLNVLHVRLYAEAEYSLALLKVVTIIIFFIVSIICNAGKNPQHEYIG 
               
               
                   
               
               
                 FKYWSYGDAPFVDGIRGFSKVFASAAYSFGGLESVSLTAGETKNPTRVIPKTVQMTFFRVLIFYILTAFFIG 
               
               
                   
               
               
                 MNIPYDYPNLLTKKVATSPFTIVFQMVGAKGAGSFMNAVIMTSIVSAGNHALYAGSRLAYNLSLHGYIPKIF 
               
               
                   
               
               
                 LPMNRFRVPYVAVIITWLIGGLCFASAFVGSGELWSWLQAIVGLSNLISWWVIGVVSIRFRRGLEKQGRTHE 
               
               
                   
               
               
                 LLFKNWSYPYGPLYVVILGGFIILVQGWTTFSPFSVNDFFQSYLELGVFPLCFVFWWLVVRKGKDKFVKFED 
               
               
                   
               
               
                 MDFDTDRYYETPEEIEKNRYANSLKGWAKFKYNFADNFL* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 GGLESVSLTAGETKNP 
                 246 
                 0.90 
               
               
                 1 
                 HEYIGFKYWSYGDAPF 
                 212 
                 0.90 
               
               
                 2 
                 IEDASTSSEHRVAQTE 
                 24 
                 0.87 
               
               
                 2 
                 YWSYGDAPFVDGIRGF 
                 219 
                 0.87 
               
               
                 3 
                 TGIFLGMGKMLSNAGP 
                 61 
                 0.86 
               
               
                 3 
                 TWLIGGLCFASAFVGS 
                 376 
                 0.86 
               
               
                 3 
                 NIPYDYPNLLTKKVAT 
                 290 
                 0.86 
               
               
                 4 
                 YYETPEEIEKNRYANS 
                 512 
                 0.85 
               
               
                 5 
                 EMSVQYPISGSFAVYT 
                 99 
                 0.83 
               
               
                 5 
                 KFEDMDFDTDRYYETP 
                 501 
                 0.83 
               
               
                 5 
                 FQMVGAKGAGSFMNAV 
                 312 
                 0.83 
               
               
                 6 
                 VQGWTTFSPFSVNDFF 
                 457 
                 0.82 
               
               
                 6 
                 AGSRLAYNLSLHGYIP 
                 342 
                 0.82 
               
               
                 6 
                 MTSIVSAGNHALYAGS 
                 329 
                 0.82 
               
               
                 6 
                 SVEYPNSVTSLDKKPQ 
                 2 
                 0.82 
               
               
                 7 
                 SGELWSWLQAIVGLSN 
                 391 
                 0.80 
               
               
                 8 
                 HRVAQTENLNRSLGAR 
                 33 
                 0.79 
               
               
                 9 
                 AGETKNPTRVIPKTVQ 
                 255 
                 0.78 
               
               
                 10 
                 LCFVFWWLVVRKGKDK 
                 483 
                 0.75 
               
               
                 10 
                 KQGRTHELLFKNWSYP 
                 426 
                 0.75 
               
               
                 10 
                 SDSLAFATLFNYWLND 
                 119 
                 0.75 
               
               
                 10 
                 ISGSFAVYTKRFGSDS 
                 106 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 464 
                 494 
                 483 
                 SPFSVNDFFQSYLELGVFPLCFVFWWLVVRK 
               
               
                 441 
                 460 
                 447 
                 PYGPLYVVILGGFIILVQGW 
               
               
                 132 
                 150 
                 145 
                 LNDCVSVAADLVALQLVMQ 
               
               
                 367 
                 392 
                 371 
                 RVPYVAVIITWLIGGLCFASAFVGSG 
               
               
                 156 
                 205 
                 189 
                 HWYVISIIFWVFLLLLNVLHVRLYAEAEYSLALLKVVT 
               
               
                   
                   
                   
                 IIIFFIVSIICN 
               
               
                 262 
                 286 
                 279 
                 TRVIPKTVQMTFFRVLIFYILTAFF 
               
               
                 409 
                 419 
                 415 
                 SWWVIGVVSIR 
               
               
                 50 
                 58 
                 55 
                 INLICLGGV 
               
               
                 76 
                 88 
                 82 
                 PLGLLLNYLIMGS 
               
               
                 395 
                 407 
                 401 
                 WSWLQAIVGLSNL 
               
               
                 234 
                 246 
                 240 
                 FSKVFASAAYSFG 
               
               
                 328 
                 362 
                 330 
                 IMTSIVSAGNHALYAGSRLAYNLSLHGYIPKIFLP 
               
               
                 98 
                 115 
                 104 
                 GEMSVQYPISGSFAVYTK 
               
               
                 292 
                 315 
                 312 
                 PYDYPNLLTKKVATSPFTIVFQMV 
               
               
                 120 
                 130 
                 125 
                 DSLAFATLFNY 
               
               
                 248 
                 254 
                 251 
                 LESVSLT 
               
               
                 14 
                 23 
                 21 
                 KKPQVDLENV 
               
               
                 4 
                 12 
                 6 
                 EYPNSVTSL 
               
               
                 224 
                 231 
                 225 
                 DAPFVDGI 
               
               
                 431 
                 437 
                 433 
                 HELLFKN 
               
               
                 212 
                 220 
                 217 
                 HEYIGFKYW 
               
               
                 497 
                 502 
                 499 
                 DKFVKF 
               
               
                   
               
            
           
           
               
               
            
               
                 32. RAD23 
                   
               
               
                 MQIIFKDFKKQTVSLDVELTDTVLSTKEKLAQEKSCESSQIKLVYSGKVLQDDKDLQSYKLKEGASIIFMIN 
               
               
                   
               
               
                 KTKKTPTPVPETKSTTGTSNVENKSTTESSTQNKAQGSTNESTTTTSSSSAPAPAPAGATTTTSEQQQPQPA 
               
               
                   
               
               
                 ASNESTFAVGSEREASIQNIMEMGYERPQVEAALRAAFNNPHRAVEYLLTGIPESLQHPVAPAQPPATGTAP 
               
               
                   
               
               
                 AQQTEGNTSESGQQGEDEEHEGDESTQHENLFEAAAAAAAGAGAGGAGSGAGAGAGSAEGDIGGLGDDQQMQ 
               
               
                   
               
               
                 LLRAALQSNPELIQPLLEQLAASNPQIANLIQQDPEAFIRMFLSGAPGSGNDLGFEFEDESGETGAGGAAAA 
               
               
                   
               
               
                 ATGEDEQGTIRIQLSEQDNNAINRLCELGFERDIVIQVYLACDKNEEVAADILFRDM* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 PELIQPLLEQLAASNP 
                 298 
                 0.93 
               
               
                 1 
                 TGIPESLQHPVAPAQP 
                 194 
                 0.93 
               
               
                 2 
                 PETKSTTGTSNVENKS 
                 82 
                 0.91 
               
               
                 2 
                 PATGTAPAQQTEGNTS 
                 210 
                 0.91 
               
               
                 2 
                 TSSSSAPAPAPAGATT 
                 118 
                 0.91 
               
               
                 3 
                 AVEYLLTGIPESLQHP 
                 188 
                 0.90 
               
               
                 4 
                 AGAGGAGSGAGAGAGS 
                 258 
                 0.89 
               
               
                 5 
                 ERPQVEAALRAAFNNP 
                 170 
                 0.88 
               
               
                 6 
                 ESSQIKLVYSGKVLQD 
                 37 
                 0.85 
               
               
                 6 
                 EASIQNIMEMGYERPQ 
                 158 
                 0.85 
               
               
                 6 
                 PAPAGATTTTSEQQQP 
                 126 
                 0.85 
               
               
                 7 
                 ANLIQQDPEAFIRMFL 
                 316 
                 0.84 
               
               
                 7 
                 MQLLRAALQSNPELIQ 
                 287 
                 0.84 
               
               
                 7 
                 GSTNESTTTTSSSSAP 
                 109 
                 0.84 
               
               
                 8 
                 KTKKTPTPVPETKSTT 
                 73 
                 0.83 
               
               
                 8 
                 DESGETGAGGAAAAAT 
                 347 
                 0.83 
               
               
                 8 
                 SESGQQGEDEEHEGDE 
                 225 
                 0.83 
               
               
                 8 
                 VAPAQPPATGTAPAQQ 
                 204 
                 0.83 
               
               
                 9 
                 ASIIFMINKTKKTPTP 
                 65 
                 0.80 
               
               
                 10 
                 SAEGDIGGLGDDQQMQ 
                 273 
                 0.79 
               
               
                 10 
                 EDEEHEGDESTQHENL 
                 232 
                 0.79 
               
               
                 11 
                 DIVIQVYLACDKNEEV 
                 393 
                 0.78 
               
               
                 11 
                 TIRIQLSEQDNNAINR 
                 369 
                 0.78 
               
               
                 12 
                 PAQQTEGNTSESGQQG 
                 216 
                 0.77 
               
               
                 13 
                 SSTQNKAQGSTNESTT 
                 101 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 392 
                 403 
                 397 
                 RDIVIQVYLACD 
               
               
                 10 
                 27 
                 16 
                 KQTVSLDVELTDTVLSTK 
               
               
                 32 
                 53 
                 47 
                 QEKSCESSQIKLVYSGKVLQDD 
               
               
                 186 
                 210 
                 203 
                 HRAVEYLLTGIPESLQHPVAPAQPP 
               
               
                 287 
                 313 
                 302 
                 MQLLRAALQSNPELIQPLLEQLAASNP 
               
               
                 171 
                 180 
                 175 
                 RPQVEAALRA 
               
               
                 383 
                 389 
                 387 
                 NRLCELG 
               
               
                 56 
                 62 
                 59 
                 LQSYKLK 
               
               
                 315 
                 322 
                 316 
                 IANLIQQD 
               
               
                 64 
                 70 
                 68 
                 GASIIFM 
               
               
                 121 
                 129 
                 126 
                 SSAPAPAPA 
               
               
                 249 
                 257 
                 250 
                 EAAAAAAAG 
               
               
                 78 
                 84 
                 79 
                 PTPVPET 
               
               
                   
               
            
           
           
               
               
            
               
                 33. RFA1 
                   
               
               
                 MSSLQLSKGALKQVFSKEGHDSVQIPMILQITNIKAFDVSPSDSKKFRILVNDGVYSTHGLIDESCSEYIKN 
               
               
                   
               
               
                 NNCQRYAIVQVNAFSIFATSKHFFVIKNFEVLAPTSEKSPNNIIPIDTYFLEHPEENYLTVMKKSESRDRES 
               
               
                   
               
               
                 PVPGVTPPLAQSTNSFKSEVGGGVAAQSKPAGTHRKVSPIETISPYQNNWTIKARVSYKGDLRTWSNSKGEG 
               
               
                   
               
               
                 KVFGFNLLDESDEIKASAFNETAERAHKLLEEGKVYYISKARVAAARKKFNTLSHPYELTFDKDTEITECFD 
               
               
                   
               
               
                 ESDVPKLNFNFVKLDQVQNLEANAIIDVLGALKTVFPPFQITAKSTGKVFDRRNILVVDETGFGIELGLWNN 
               
               
                   
               
               
                 TATDFNIEEGTVVAVKGCKVSDYDGRTLSLTQAGSIIPNPGTPESFKLKGWYDNIGIHESFKSLKIDNAGSG 
               
               
                   
               
               
                 GDKISQRISINQALEEHSGSTEKPDYFSIKASVTFCKPENFAYPACPNLVQNADATRPAQVCNKKLVFQDND 
               
               
                   
               
               
                 GTWRCERCAKTYEEPTWRYVLSCSVTDSTGHMWVTLFNDQAEKLLGIDATELVKKKEQKSEVANQIMNNTLF 
               
               
                   
               
               
                 KEFSLRVKAKQETYNDELKTRYSAAGINELDYASESQFLIKKLDQLLK* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 KSESRDRESPVPGVTP 
                 136 
                 0.96 
               
               
                 2 
                 YFSIKASVTFCKPENF 
                 458 
                 0.95 
               
               
                 3 
                 AKTYEEPTWRYVLSCS 
                 513 
                 0.94 
               
               
                 3 
                 DVSPSDSKKFRILVND 
                 38 
                 0.94 
               
               
                 4 
                 HGLIDESCSEYIKNNN 
                 59 
                 0.93 
               
               
                 5 
                 GSIIPNPGTPESFKLK 
                 394 
                 0.91 
               
               
                 6 
                 NWTIKARVSYKGDLRT 
                 193 
                 0.89 
               
               
                 7 
                 SGSTEKPDYFSIKASV 
                 450 
                 0.88 
               
               
                 7 
                 AGSGGDKISQRISINQ 
                 429 
                 0.88 
               
               
                 7 
                 PGTPESFKLKGWYDNI 
                 400 
                 0.88 
               
               
                 7 
                 YLTVMKKSESRDRESP 
                 130 
                 0.88 
               
               
                 8 
                 SVTFCKPENFAYPACP 
                 464 
                 0.87 
               
               
                 8 
                 DKDTEITECFDESDVP 
                 278 
                 0.87 
               
               
                 9 
                 DGVYSTHGLIDESCSE 
                 53 
                 0.86 
               
               
                 9 
                 DNDGTWRCERCAKTYE 
                 502 
                 0.86 
               
               
                 9 
                 NFEVLAPTSEKSPNNI 
                 100 
                 0.86 
               
               
                 10 
                 TGFGIELGLWNNTATD 
                 349 
                 0.85 
               
               
                 11 
                 TECFDESDVPKLNFNF 
                 284 
                 0.84 
               
               
                 11 
                 THRKVSPIETISPYQN 
                 177 
                 0.84 
               
               
                 11 
                 EHPEENYLTVMKKSES 
                 124 
                 0.84 
               
               
                 12 
                 GCKVSDYDGRTLSLTQ 
                 377 
                 0.83 
               
               
                 12 
                 GDLRTWSNSKGEGKVF 
                 204 
                 0.83 
               
               
                 13 
                 RISINQALEEHSGSTE 
                 439 
                 0.82 
               
               
                 13 
                 IIPIDTYFLEHPEENY 
                 115 
                 0.82 
               
               
                 14 
                 SLKIDNAGSGGDKISQ 
                 423 
                 0.81 
               
               
                 14 
                 ANAIIDVLGALKTVFP 
                 310 
                 0.81 
               
               
                 15 
                 GVAAQSKPAGTHRKVS 
                 167 
                 0.80 
               
               
                 16 
                 YNDELKTRYSAAGINE 
                 590 
                 0.79 
               
               
                 16 
                 GRTLSLTQAGSIIPNP 
                 385 
                 0.79 
               
               
                 16 
                 FNIEEGTVVAVKGCKV 
                 365 
                 0.79 
               
               
                 16 
                 VYYISKARVAAARKKF 
                 251 
                 0.79 
               
               
                 16 
                 LKQVFSKEGHDSVQIP 
                 11 
                 0.79 
               
               
                 17 
                 PIETISPYQNNWTIKA 
                 183 
                 0.78 
               
               
                 18 
                 AFSIFATSKHFFVIKN 
                 85 
                 0.77 
               
               
                 18 
                 KKKEQKSEVANQIMNN 
                 558 
                 0.77 
               
               
                 18 
                 PVPGVTPPLAQSTNSF 
                 145 
                 0.77 
               
               
                 19 
                 CSVTDSTGHMWVTLFN 
                 527 
                 0.76 
               
               
                 19 
                 NLVQNADATRPAQVCN 
                 480 
                 0.76 
               
               
                 19 
                 AYPACPNLVQNADATR 
                 474 
                 0.76 
               
               
                 19 
                 NSKGEGKVFGFNLLDE 
                 211 
                 0.76 
               
               
                 20 
                 LLGIDATELVKKKEQK 
                 548 
                 0.75 
               
               
                 20 
                 PPLAQSTNSFKSEVGG 
                 151 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 521 
                 530 
                 526 
                 WRYVLSCSVT 
               
               
                 370 
                 383 
                 375 
                 GTVVAVKGCKVSDY 
               
               
                 490 
                 501 
                 496 
                 PAQVCNKKLVFQ 
               
               
                 76 
                 107 
                 78 
                 QRYAIVQVNAFSIFATSKHFFVIKNFEVLAPT 
               
               
                 473 
                 485 
                 479 
                 FAYPACPNLVQNA 
               
               
                 297 
                 308 
                 302 
                 FNFVKLDQVQNL 
               
               
                 248 
                 263 
                 254 
                 EGKVYYISKARVAAAR 
               
               
                 313 
                 330 
                 326 
                 IIDVLGALKTVFPPFQIT 
               
               
                 20 
                 32 
                 26 
                 HDSVQIPMILQIT 
               
               
                 458 
                 471 
                 466 
                 YFSIKASVTFCKPE 
               
               
                 342 
                 348 
                 346 
                 NILVVDE 
               
               
                 144 
                 156 
                 152 
                 SPVPGVTPPLAQS 
               
               
                 4 
                 17 
                 13 
                 LQLSKGALKQVFSK 
               
               
                 56 
                 69 
                 58 
                 YSTHGLIDESCSEY 
               
               
                 47 
                 54 
                 53 
                 FRILVNDG 
               
               
                 268 
                 276 
                 272 
                 TLSHPYELT 
               
               
                 611 
                 621 
                 616 
                 ESQFLIKKLDQ 
               
               
                 577 
                 586 
                 582 
                 KEFSLRVKAK 
               
               
                 197 
                 203 
                 199 
                 KARVSYK 
               
               
                 165 
                 173 
                 171 
                 GGGVAAQSK 
               
               
                 178 
                 189 
                 184 
                 HRKVSPIETISP 
               
               
                 36 
                 42 
                 37 
                 AFDVSPS 
               
               
                 117 
                 125 
                 120 
                 PIDTYFLEH 
               
               
                 554 
                 559 
                 554 
                 TELVKK 
               
               
                 509 
                 515 
                 512 
                 CERCAKT 
               
               
                 387 
                 398 
                 390 
                 TLSLTQAGSIIP 
               
               
                 546 
                 551 
                 550 
                 EKLLGI 
               
               
                 418 
                 424 
                 423 
                 HESFKSL 
               
               
                   
               
            
           
           
               
               
            
               
                 34. IPF9141 
                   
               
               
                 MSLQKISAFPDGNSFVHFNHSIGKLVIANSEGLMKILNTNDPESQPISIDILDNLTSLSSHEDKSIVLTTTE 
               
               
                   
               
               
                 GKLELIDLSTNTSKGVLYRSELPLRDTVFINQGNRVLCGGDENKLVIVDLQTTGEEDSNNKVSTISLPDQVV 
               
               
                   
               
               
                 NISYNTSGELSAISLSNGNVQIYSVVNEQPNLIYTINSVIPTKIHTSMDKVDYNDEHHDELFSTKTQWSTNG 
               
               
                   
               
               
                 QLLLVPTIDNQIHVYDRQDWTKVVKEFNNDNVKIIDFNLSAQGNLAIMSLNSFKVYNFSSEKLINEDDFEFD 
               
               
                   
               
               
                 EDGYPLNIIWKDNNLFVGSTVGETLHLRNVVKGKTDDVLNSLFISDAEEEEEEEEREVGRKKLGVEEDEGND 
               
               
                   
               
               
                 TDALLRDSDIEQDINVEDRIGQRKRNRRPYKLHEEDDLVIDEDDNENLGFDDRVVSNGYSTNGHKRYKSRSP 
               
               
                   
               
               
                 SEAIPKISKIKPYSPGSTPFEHRGASADRRYLTMNNIGYTWVVQNKDTTDDATSGSGSGGNSITVSFFDRSL 
               
               
                   
               
               
                 NTEYHFTDYHNFDLASMNQRGVLLGTSSTGHIYYRSHNEATNDSWDRKLPLLVSEYITSICITNNASATNTI 
               
               
                   
               
               
                 IVGTNLGYLRFFNQFGVCINILKTLPVVTLIASATVNAKLFVINQVTTNVYSYSILDINQDYKYIPHNAPMP 
               
               
                   
               
               
                 LKDHTPLIKGIFFNEFNDPCIVGGEDDTLLILHSWRESNNAKWIPILNCHKVLTEYGTNSNKKNWKCWPLGF 
               
               
                   
               
               
                 IGDKLNCLILKNNSQYPGFPLPLPIELEVELPIKNKFEEDEAEENFLRSLTLGKLISDSLNDELPGEIEEDE 
               
               
                   
               
               
                 VMERLNQYSMLFDKSLLKLFGESCKESKLGKAFSIARLIKTDKALLAASRIAERMEFLNLASKIGQLRESLV 
               
               
                   
               
               
                 DIDGDSD* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 HKVLTEYGTNSNKKNW 
                 698 
                 0.95 
               
               
                 1 
                 TGHIYYRSHNEATNDS 
                 533 
                 0.95 
               
               
                 2 
                 GVEEDEGNDTDALLRD 
                 352 
                 0.92 
               
               
                 3 
                 DTTDDATSGSGSGGNS 
                 479 
                 0.90 
               
               
                 3 
                 KLHEEDDLVIDEDDNE 
                 391 
                 0.90 
               
               
                 3 
                 EEEEEEREVGRKKLGV 
                 338 
                 0.90 
               
               
                 4 
                 ASRIAERMEFLNLASK 
                 840 
                 0.89 
               
               
                 4 
                 ASADRRYLTMNNIGYT 
                 457 
                 0.89 
               
               
                 5 
                 PGEIEEDEVMERLNQY 
                 785 
                 0.88 
               
               
                 5 
                 HTPLIKGIFFNEFNDP 
                 652 
                 0.88 
               
               
                 5 
                 VGRKKLGVEEDEGNDT 
                 346 
                 0.88 
               
               
                 6 
                 PSEAIPKISKIKPYSP 
                 432 
                 0.87 
               
               
                 6 
                 EGLMKILNTNDPESQP 
                 31 
                 0.87 
               
               
                 6 
                 IHTSMDKVDYNDEHHD 
                 188 
                 0.87 
               
               
                 6 
                 QVVNISYNTSGELSAI 
                 142 
                 0.87 
               
               
                 6 
                 LVIVDLQTTGEEDSNN 
                 117 
                 0.87 
               
               
                 7 
                 PLLVSEYITSICITNN 
                 554 
                 0.86 
               
               
                 7 
                 NTEYHFTDYHNFDLAS 
                 505 
                 0.86 
               
               
                 7 
                 YSPGSTPFEHRGASAD 
                 445 
                 0.86 
               
               
                 7 
                 QIHVYDRQDWTKVVKE 
                 227 
                 0.86 
               
               
                 7 
                 VSTISLPDQVVNISYN 
                 134 
                 0.86 
               
               
                 8 
                 RVVSNGYSTNGHKRYK 
                 413 
                 0.85 
               
               
                 8 
                 LQKISAFPDGNSFVHF 
                 3 
                 0.85 
               
               
                 9 
                 DLVIDEDDNENLGFDD 
                 397 
                 0.84 
               
               
                 9 
                 ALLRDSDIEQDINVED 
                 363 
                 0.84 
               
               
                 10 
                 ERLNQYSMLFDKSLLK 
                 795 
                 0.82 
               
               
                 10 
                 MNNIGYTWVVQNKDTT 
                 466 
                 0.82 
               
               
                 10 
                 NGHKRYKSRSPSEAIP 
                 422 
                 0.82 
               
               
                 10 
                 VPTIDNQIHVYDRQDW 
                 221 
                 0.82 
               
               
                 10 
                 SGELSAISLSNGNVQI 
                 151 
                 0.82 
               
               
                 11 
                 GSTVGETLHLRNVVKG 
                 306 
                 0.81 
               
               
                 11 
                 KLINEDDFEFDEDGYP 
                 278 
                 0.81 
               
               
                 12 
                 NLASKIGQLRESLVDI 
                 851 
                 0.80 
               
               
                 12 
                 TNNASATNTIIVGTNL 
                 567 
                 0.80 
               
               
                 13 
                 DKSIVLTTTEGKLELI 
                 63 
                 0.78 
               
               
                 13 
                 LGYLRFFNQFGVCINI 
                 582 
                 0.78 
               
               
                 13 
                 GGNSITVSFFDRSLNT 
                 491 
                 0.78 
               
               
                 13 
                 KLVIANSEGLMKILNT 
                 24 
                 0.78 
               
               
                 14 
                 HDELFSTKTQWSTNGQ 
                 202 
                 0.77 
               
               
                 15 
                 KLFGESCKESKLGKAF 
                 810 
                 0.76 
               
               
                 15 
                 GFIGDKLNCLILKNNS 
                 719 
                 0.76 
               
               
                 15 
                 ITSICITNNASATNTI 
                 561 
                 0.76 
               
               
                 16 
                 ILDINQDYKYIPHNAP 
                 631 
                 0.75 
               
               
                 16 
                 SATVNAKLFVINQVTT 
                 609 
                 0.75 
               
               
                 16 
                 FDEDGYPLNIIWKDNN 
                 287 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 164 
                 173 
                 167 
                 VQIYSVVNEQ 
               
               
                 590 
                 621 
                 604 
                 QFGVCINILKTLPVVTLIASATVNAKLFVINQ 
               
               
                 116 
                 123 
                 120 
                 KLVIVDLQ 
               
               
                 216 
                 224 
                 221 
                 GQLLLVPTI 
               
               
                 552 
                 568 
                 555 
                 KLPLLVSEYITSICITN 
               
               
                 623 
                 635 
                 629 
                 TTNVYSYSILDIN 
               
               
                 691 
                 703 
                 698 
                 WIPILNCEKVLTE 
               
               
                 724 
                 731 
                 727 
                 KLNCLILK 
               
               
                 310 
                 321 
                 316 
                 GETLHLRNVVKG 
               
               
                 135 
                 147 
                 141 
                 STISLPDQVVNIS 
               
               
                 737 
                 752 
                 742 
                 PGFPLPLPIELEVELP 
               
               
                 676 
                 682 
                 679 
                 TLLILHS 
               
               
                 326 
                 333 
                 329 
                 VLNSLFIS 
               
               
                 302 
                 308 
                 306 
                 NLFVGST 
               
               
                 22 
                 29 
                 25 
                 IGKLVIAN 
               
               
                 86 
                 103 
                 91 
                 KGVLYRSELPLRDTVFIN 
               
               
                 471 
                 477 
                 472 
                 YTWVVQN 
               
               
                 154 
                 159 
                 157 
                 LSAISL 
               
               
                 666 
                 671 
                 667 
                 DPCIVG 
               
               
                 715 
                 722 
                 718 
                 CWPLGFIG 
               
               
                 805 
                 815 
                 809 
                 DKSLLKLFGES 
               
               
                 175 
                 188 
                 186 
                 NLIYTINSVIPTKI 
               
               
                 525 
                 530 
                 529 
                 GVLLGT 
               
               
                 833 
                 842 
                 840 
                 TDKALLAASR 
               
               
                 495 
                 501 
                 497 
                 ITVSFFD 
               
               
                 44 
                 61 
                 49 
                 SQPISIDILDNLTSLSSH 
               
               
                 767 
                 778 
                 769 
                 LRSLTLGKLISD 
               
               
                 859 
                 867 
                 861 
                 LRESLVDID 
               
               
                 75 
                 80 
                 78 
                 LELIDL 
               
               
                 13 
                 20 
                 19 
                 NSFVHFNH 
               
               
                 268 
                 274 
                 269 
                 SFKVYNF 
               
               
                 411 
                 418 
                 417 
                 DDRVVSNG 
               
               
                 822 
                 831 
                 828 
                 GKAFSIARLI 
               
               
                 575 
                 588 
                 585 
                 TIIVGTNLGYLRFF 
               
               
                 534 
                 539 
                 538 
                 GHIYYR 
               
               
                 227 
                 233 
                 230 
                 QIHVYDR 
               
               
                 64 
                 70 
                 67 
                 KSIVLTT 
               
               
                 651 
                 659 
                 658 
                 DHTPLIKGI 
               
               
                 4 
                 9 
                 6 
                 QKISAF 
               
               
                 237 
                 242 
                 240 
                 TKVVKE 
               
               
                 637 
                 644 
                 640 
                 DYKYIPHN 
               
               
                 850 
                 857 
                 853 
                 LNLASKIG 
               
               
                 433 
                 449 
                 442 
                 SEAIPKISKIKPYSPGS 
               
               
                 248 
                 256 
                 250 
                 VKIIDFNLS 
               
               
                 395 
                 401 
                 398 
                 EDDLVID 
               
               
                 348 
                 353 
                 350 
                 RKKLGV 
               
               
                   
               
            
           
           
               
               
            
               
                 35. IPF19872 
                   
               
               
                 MENIENLKLYINSLSQSISAYESALSPLQNKQLSDMILNINTTSSTTSTTSTSEEQQIQILNNFAYLLISTL 
               
               
                   
               
               
                 FSYLKSLGIDTDSHPIKMELSRIKSSMNRLKNIKNEINGDTNKQEEEEEEKEKLKKSKEYLSRTLGVRDVGS 
               
               
                   
               
               
                 SVDVKSMGTSAISKQNFQGKHIKFDDHDNADEKKDDGNKNDLKKSKNKKPNSTGSKSNSKSKSKLNVKESKI 
               
               
                   
               
               
                 TKPKSNKKSSTKNKNK* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 SQSISAYESALSPLQN 
                 15 
                 0.89 
               
               
                 2 
                 GKHIKFDDHDNADEKK 
                 163 
                 0.88 
               
               
                 3 
                 KESKITKPKSNKKSST 
                 212 
                 0.86 
               
               
                 3 
                 DEKKDDGNKNDLKKSK 
                 175 
                 0.86 
               
               
                 4 
                 SLGIDTDSHPIKMELS 
                 78 
                 0.85 
               
               
                 5 
                 KKPNSTGSKSNSKSKS 
                 192 
                 0.82 
               
               
                 6 
                 TTSSTTSTTSTSEEQQ 
                 42 
                 0.81 
               
               
                 7 
                 TSAISKQNFQGKHIKF 
                 153 
                 0.80 
               
               
                 8 
                 MELSRIKSSMNRLKNI 
                 90 
                 0.79 
               
               
                 8 
                 VDVKSMGTSAISKQNF 
                 146 
                 0.79 
               
               
                 9 
                 LSPLQNKQLSDMILNI 
                 25 
                 0.78 
               
               
                 10 
                 TNKQEEEEEEKEKLKK 
                 113 
                 0.77 
               
               
                 11 
                 EYLSRTLGVRDVGSSV 
                 131 
                 0.76 
               
               
                 12 
                 GNKNDLKKSKNKKPNS 
                 181 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 56 
                 82 
                 69 
                 QQIQILNNFAYLLISTLFSYLKSLGID 
               
               
                 129 
                 149 
                 145 
                 SKEYLSRTLGVRDVGSSVDVK 
               
               
                 6 
                 31 
                 26 
                 NLKLYINSLSQSISAYESALSPLQNK 
               
               
                 208 
                 214 
                 208 
                 KLNVKES 
               
               
                 84 
                 95 
                 95 
                 DSHPIKMELSRI 
               
               
                 163 
                 168 
                 168 
                 GKHIKF 
               
               
                   
               
            
           
           
               
               
            
               
                 36. LPD1 
                   
               
               
                 MLRSFKSIPANGKLAQFVRYASTKKYDVVVIGGGPGGYVAAIKAAQLGLNTACIEKRGALGGTCLNVGCIPS 
               
               
                   
               
               
                 KSLLNNSHLLHQIQHEAKERGISIQGEVGVDFPKLMAAKEKAVKQLTGGIEMLFKKNKVDYLKGAGSFVNEK 
               
               
                   
               
               
                 TVKVTPIDGSEAQEVEADHIIVATGSEPTPFPGIEIDEERIVTSTGILSLKEVPERLAIIGGGIIGLEMASV 
               
               
                   
               
               
                 YARLGSKVTVIEFQNAIGAGMDAEVAKQSQKLLAKQGLDFKLGTKVVKGERDGEVVKIEVEDVKSGKKSDLE 
               
               
                   
               
               
                 ADVLLVAIGRRPFTEGLNFEAIGLEKDNKGRLIIDDQFKTKHDHIRVIGDVTFGPMLAHKAEEEGIAAAEYI 
               
               
                   
               
               
                 KKGHGHVNYANIPSVMYTHPEVAWVGLNEEQLKEQGIKYKVGKFPFIANSRAKTNMDTDGFVKFIADAETQR 
               
               
                   
               
               
                 VLGVHIIGPNAGEMIAEAGLALEYGASTEDISRTCHAHPTLSEAFKEAALATFDKPINF* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 SVMYTHPEVAWVGLNE 
                 374 
                 0.95 
               
               
                 2 
                 GVHIIGPNAGEMIAEA 
                 435 
                 0.94 
               
               
                 3 
                 TEDISRTCHAHPTLSE 
                 460 
                 0.90 
               
               
                 4 
                 AKTNMDTDGFVKFIAD 
                 412 
                 0.89 
               
               
                 4 
                 AEYIKKGHGHVNYANI 
                 357 
                 0.89 
               
               
                 5 
                 HIRVIGDVTFGPMLAH 
                 332 
                 0.86 
               
               
                 5 
                 LLVAIGRRPFTEGLNF 
                 292 
                 0.86 
               
               
                 5 
                 EKTVKVTPIDGSEAQE 
                 143 
                 0.86 
               
               
                 6 
                 AFKEAALATFDKPINF 
                 476 
                 0.85 
               
               
                 6 
                 VTVIEFQNAIGAGMDA 
                 224 
                 0.85 
               
               
                 7 
                 VAAIKAAQLGLNTACI 
                 39 
                 0.84 
               
               
                 8 
                 EQLKEQGIKYKVGKFP 
                 390 
                 0.83 
               
               
                 9 
                 ALEYGASTEDISRTCH 
                 453 
                 0.82 
               
               
                 9 
                 VEDVKSGKKSDLEADV 
                 276 
                 0.82 
               
               
                 9 
                 DVVVIGGGPGGYVAAI 
                 27 
                 0.82 
               
               
                 10 
                 TCLNVGCIPSKSLLNN 
                 63 
                 0.81 
               
               
                 10 
                 KGAGSFVNEKTVKVTP 
                 135 
                 0.81 
               
               
                 11 
                 TACIEKRGALGGTCLN 
                 51 
                 0.80 
               
               
                 11 
                 HPTLSEAFKEAALATF 
                 470 
                 0.80 
               
               
                 11 
                 LGTKVVKGERDGEVVK 
                 258 
                 0.80 
               
               
                 11 
                 QNAIGAGMDAEVAKQS 
                 230 
                 0.80 
               
               
                 11 
                 LRSFKSIPANGKLAQF 
                 2 
                 0.80 
               
               
                 11 
                 TSTGILSLKEVPERLA 
                 187 
                 0.80 
               
               
                 12 
                 GISIQGEVGVDFPKLM 
                 93 
                 0.79 
               
               
                 12 
                 FPGIEIDEERIVTSTG 
                 175 
                 0.79 
               
               
                 12 
                 VKQLTGGIEMLFKKNK 
                 115 
                 0.79 
               
               
                 13 
                 HGHVNYANIPSVMYTH 
                 364 
                 0.78 
               
               
                 14 
                 FPFIANSRAKTNMDTD 
                 404 
                 0.77 
               
               
                 15 
                 EEEGIAAAEYIKKGHG 
                 350 
                 0.76 
               
               
                 15 
                 IGLEMASVYARLGSKV 
                 209 
                 0.76 
               
               
                 15 
                 ATGSEPTPFPGIEIDE 
                 167 
                 0.76 
               
               
                 16 
                 EVGVDFPKLMAAKEKA 
                 99 
                 0.75 
               
               
                 16 
                 ADHIIVATGSEPTPFP 
                 161 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 288 
                 297 
                 294 
                 EADVLLVAIG 
               
               
                 431 
                 440 
                 436 
                 QRVLGVHIIG 
               
               
                 61 
                 87 
                 67 
                 GGTCLNVGCIPSKSLLNNSHLLHQIQH 
               
               
                 25 
                 33 
                 28 
                 KYDVVVIGG 
               
               
                 269 
                 279 
                 273 
                 GEVVKIEVEDV 
               
               
                 464 
                 476 
                 470 
                 SRTCHAHPTLSEA 
               
               
                 14 
                 21 
                 17 
                 LAQFVRYA 
               
               
                 185 
                 206 
                 194 
                 IVTSTGILSLKEVPERLAIIGG 
               
               
                 36 
                 56 
                 41 
                 GGYVAAIKAAQLGLNTACIEK 
               
               
                 211 
                 230 
                 217 
                 LEMASVYARLGSKVTVIEFQ 
               
               
                 156 
                 169 
                 164 
                 AQEVEADHIIVATG 
               
               
                 364 
                 386 
                 382 
                 HGHVNYANIPSVMYTHPEVAWVG 
               
               
                 143 
                 151 
                 148 
                 EKTVKVTPI 
               
               
                 332 
                 348 
                 336 
                 HIRVIGDVTFGPMLAHK 
               
               
                 259 
                 265 
                 260 
                 GTKVVKG 
               
               
                 241 
                 253 
                 251 
                 VAKQSQKLLAKQG 
               
               
                 97 
                 108 
                 103 
                 QGEVGVDFPKLM 
               
               
                 421 
                 426 
                 423 
                 FVKFIA 
               
               
                 398 
                 409 
                 404 
                 KYKVGKFPFIAN 
               
               
                 131 
                 140 
                 134 
                 VDYLKGAGSF 
               
               
                 449 
                 457 
                 455 
                 EAGLALEYG 
               
               
                 112 
                 119 
                 116 
                 EKAVKQLT 
               
               
                 319 
                 324 
                 323 
                 RLIIDD 
               
               
                 479 
                 486 
                 479 
                 EAALATFD 
               
               
                   
               
            
           
           
               
               
            
               
                 37. PDB1 
                   
               
               
                 MSSLSSVTRSAKLATQSLKYNTRPSLSKIGQFQTSKITYRANSTQSTPVKEITVRDALNQALSEELDRDEDV 
               
               
                   
               
               
                 FLMGEEVAQYNGAYKVSRGLLDKFGEKRVIDTPITEMGFTGLAVGAALHGLKPVLEFMTWNFAMQGIDHILN 
               
               
                   
               
               
                 SAAKTLYMSGGKQPCNITFRGPNGAAAGVAAQHSQCYAAWYGSIPGLKVLSPYSAEDYKGLLKAAIRDPNPV 
               
               
                   
               
               
                 VFLENEIAYGETFKVSEEFSSPDFILPIGKAKIEKEGTDLTIVGHSRALKFAVEAAEILEKDFGIKAEVLNL 
               
               
                   
               
               
                 RSIKPLDVPAIVDSVKKTNHLVTVENGFPGFGVGSEICAQIMESEAFDYLDAPVERVTGCEVPTPYAKELED 
               
               
                   
               
               
                 FAFPDTEVILRACKKVLSL* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 GQFQTSKITYRANSTQ 
                 30 
                 0.92 
               
               
                 2 
                 CAQIMESEAFDYLDAP 
                 326 
                 0.91 
               
               
                 3 
                 RGLLDKFGEKRVIDTP 
                 90 
                 0.90 
               
               
                 4 
                 KRVIDTPITEMGFTGL 
                 99 
                 0.89 
               
               
                 5 
                 AFDYLDAPVERVTGCE 
                 334 
                 0.87 
               
               
                 5 
                 KAAIRDPNPVVFLENE 
                 207 
                 0.87 
               
               
                 6 
                 YRANSTQSTPVKEITV 
                 39 
                 0.86 
               
               
                 7 
                 YAAWYGSIPGLKVLSP 
                 181 
                 0.85 
               
               
                 7 
                 AMQGIDHILNSAAKTL 
                 135 
                 0.85 
               
               
                 8 
                 STPVKEITVRDALNQA 
                 46 
                 0.84 
               
               
                 8 
                 VERVTGCEVPTPYAKE 
                 342 
                 0.84 
               
               
                 8 
                 SAEDYKGLLKAAIRDP 
                 198 
                 0.84 
               
               
                 9 
                 NLRSIKPLDVPAIVDS 
                 287 
                 0.83 
               
               
                 10 
                 GVAAQHSQCYAAWYGS 
                 172 
                 0.82 
               
               
                 11 
                 VSEEFSSPDFILPIGK 
                 231 
                 0.81 
               
               
                 11 
                 KVLSPYSAEDYKGLLK 
                 192 
                 0.81 
               
               
                 11 
                 YMSGGKQPCNITFRGP 
                 151 
                 0.81 
               
               
                 12 
                 AQYNGAYKVSRGLLDK 
                 80 
                 0.80 
               
               
                 12 
                 AVEAAEILEKDFGIKA 
                 268 
                 0.80 
               
               
                 13 
                 ENEIAYGETFKVSEEF 
                 220 
                 0.79 
               
               
                 14 
                 TPYAKELEDFAFPDTE 
                 352 
                 0.78 
               
               
                 15 
                 GFTGLAVGAALHGLKP 
                 110 
                 0.77 
               
               
                 16 
                 VPAIVDSVKKTNHLVT 
                 296 
                 0.76 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 365 
                 376 
                 376 
                 DTEVILRACKKV 
               
               
                 282 
                 303 
                 297 
                 KAEVLNLRSIKPLDVPAIVDSV 
               
               
                 170 
                 200 
                 194 
                 AAGVAAQHSQCYAAWYGSIPGLKVLSPYSAE 
               
               
                 213 
                 222 
                 216 
                 PNPVVFLENE 
               
               
                 113 
                 129 
                 117 
                 GLAVGAALHGLKPVLEF 
               
               
                 335 
                 356 
                 348 
                 FDYLDAPVERVTGCEVPTPYAK 
               
               
                 322 
                 329 
                 324 
                 GSEICAQI 
               
               
                 305 
                 313 
                 309 
                 KTNHLVTVE 
               
               
                 256 
                 274 
                 259 
                 LTIVGHSRALKFAVEAAEI 
               
               
                 46 
                 52 
                 51 
                 STPVKEI 
               
               
                 238 
                 246 
                 241 
                 PDFILPIGK 
               
               
                 4 
                 19 
                 5 
                 LSSVTRSAKLATQSLK 
               
               
                 203 
                 210 
                 207 
                 KGLLKAAI 
               
               
                 85 
                 95 
                 90 
                 AYKVSRGLLDK 
               
               
                 140 
                 150 
                 144 
                 DHILNSAAKTL 
               
               
                 25 
                 30 
                 29 
                 SLSKIG 
               
               
                 228 
                 234 
                 234 
                 TFKVSEE 
               
               
                 71 
                 77 
                 71 
                 DVFLMGE 
               
               
                   
               
            
           
           
               
               
            
               
                 38. MDH12 
                   
               
               
                 MVKVTVAGAAGGIGQPLSLLLKLNPNVDELALFDIVNAKGVAADLSHINTPAVVTGHQPANKEDKTAITEAL 
               
               
                   
               
               
                 QGTDLVIIPAGVPRKPGMTRADLFNINASIIRDLVANIARVAPTAAILIISNPVNATVPIAAEVLKKLGVFN 
               
               
                   
               
               
                 PRKLFGVTTLDSVRAETFLGELTNTDPTKLKGKISVIGGHSGDTIVPLINYDAGVGVLSDSDYKNFVHRVQF 
               
               
                   
               
               
                 GGDEVVKAKNGAGSATLSMAYAGYRFADYVISSLTGGATPAGRIPDSSYIYLPGVSGGKEFSAKYVDGVDFF 
               
               
                   
               
               
                 SVPVVLSQGEIRSFVNPFEELTVTKEEKKLVEVALKGLKGSITQGTEFVNASKL* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 AGGIGQPLSLLLKLNP 
                 10 
                 0.94 
               
               
                 2 
                 KGSITQGTEFVNASKL 
                 327 
                 0.92 
               
               
                 3 
                 ASIIRDLVANIARVAP 
                 100 
                 0.91 
               
               
                 4 
                 LVIIPAGVPRKPGMTR 
                 77 
                 0.90 
               
               
                 5 
                 GDTIVPLINYDAGVGV 
                 186 
                 0.89 
               
               
                 6 
                 SLTGGATPAGRIPDSS 
                 249 
                 0.88 
               
               
                 7 
                 PGMTRADLFNINASII 
                 88 
                 0.87 
               
               
                 8 
                 SSYIYLPGVSGGKEFS 
                 263 
                 0.86 
               
               
                 9 
                 QGEIRSFVNPFEELTV 
                 296 
                 0.85 
               
               
                 9 
                 HRVQFGGDEVVKAKNG 
                 212 
                 0.85 
               
               
                 10 
                 PAVVTGHQPANKEDKT 
                 51 
                 0.83 
               
               
                 11 
                 TVPIAAEVLKKLGVFN 
                 129 
                 0.82 
               
               
                 12 
                 LSMAYAGYRFADYVIS 
                 233 
                 0.80 
               
               
                 13 
                 TFLGELTNTDPTKLKG 
                 161 
                 0.79 
               
               
                 13 
                 LVANIARVAPTAAILI 
                 106 
                 0.79 
               
               
                 14 
                 KKLGVFNPRKLFGVTT 
                 138 
                 0.77 
               
               
                 15 
                 AAILIISNPVNATVPI 
                 117 
                 0.76 
               
               
                 16 
                 TPAGRIPDSSYIYLPG 
                 255 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 278 
                 297 
                 291 
                 SAKYVDGVDFFSVPVVLSQG 
               
               
                 14 
                 25 
                 20 
                 GQPLSLLLKLNP 
               
               
                 316 
                 329 
                 320 
                 KKLVEVALKGLKGS 
               
               
                 74 
                 87 
                 81 
                 GTDLVIIPAGVPRK 
               
               
                 28 
                 57 
                 33 
                 DELALFDIVNAKGVAADLSHINTPAVVTGH 
               
               
                 262 
                 272 
                 268 
                 DSSYIYLPGVS 
               
               
                 127 
                 143 
                 139 
                 NATVPIAAEVLKKLGVF 
               
               
                 208 
                 215 
                 213 
                 KNFVHRVQ 
               
               
                 187 
                 196 
                 192 
                 DTIVPLINYD 
               
               
                 4 
                 9 
                 5 
                 VTVAGA 
               
               
                 242 
                 250 
                 248 
                 FADYVISSL 
               
               
                 103 
                 125 
                 120 
                 IRDLVANIARVAPTAAILIISNP 
               
               
                 198 
                 205 
                 200 
                 GVGVLSDS 
               
               
                 148 
                 157 
                 154 
                 LFGVTTLDSV 
               
               
                 176 
                 183 
                 181 
                 GKISVIGG 
               
               
                 219 
                 225 
                 222 
                 DEVVKAK 
               
               
                 300 
                 306 
                 302 
                 RSFVNPF 
               
               
                 233 
                 240 
                 239 
                 LSMAYAGY 
               
               
                   
               
            
           
           
               
               
            
               
                 39. CAR1 
                   
               
               
                 MSSIQYKYHPDKKASIITAPFSGGQPKGGVELGPDYILKAGFQKQIESLGWTTDLKEPLEGTDYEKMKTNDK 
               
               
                   
               
               
                 DDFGVKNSKIVSESCQKIHDAVKGSLAEGKLPITIGGDHSIGTATVSASLVHDPSTCVVWVDAHADINTPKT 
               
               
                   
               
               
                 TDSGNLHGCPLSFIMGIDRDSYPPEFSWVPQVLKSNKLVYIGLRDVDDGEKEILRKHNIAAFSMYHVDKYGI 
               
               
                   
               
               
                 GKVVEMALDKVNPNRDCPVHLSYDVDAIDPSFVPATGTRVEGGLSLREGLFIAEEIAQSGLLQSLDIVETNP 
               
               
                   
               
               
                 MLAETEEHVLDTVSAACAIGRCALGQTLL* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 MSSIQYKYHPDKKASI 
                 1 
                 0.96 
               
               
                 2 
                 PLEGTDYEKMKTNDKD 
                 58 
                 0.92 
               
               
                 3 
                 ASLVHDPSTCVVWVDA 
                 120 
                 0.91 
               
               
                 4 
                 DHSIGTATVSASLVHD 
                 110 
                 0.90 
               
               
                 5 
                 KMKTNDKDDFGVKNSK 
                 66 
                 0.86 
               
               
                 5 
                 KVVEMALDKVNPNRDC 
                 218 
                 0.86 
               
               
                 6 
                 INTPKTTDSGNLHGCP 
                 139 
                 0.84 
               
               
                 7 
                 APFSGGQPKGGVELGP 
                 19 
                 0.83 
               
               
                 7 
                 FIMGIDRDSYPPEFSW 
                 157 
                 0.83 
               
               
                 8 
                 DCPVHLSYDVDAIDPS 
                 232 
                 0.82 
               
               
                 9 
                 KLPITIGGDHSIGTAT 
                 102 
                 0.81 
               
               
                 10 
                 KGGVELGPDYILKAGF 
                 27 
                 0.80 
               
               
                 11 
                 SLGWTTDLKEPLEGTD 
                 48 
                 0.78 
               
               
                 11 
                 TVSAACAIGRCALGQT 
                 300 
                 0.78 
               
               
                 11 
                 LVYIGLRDVDDGEKEI 
                 182 
                 0.78 
               
               
                 12 
                 DKYGIGKVVEMALDKV 
                 212 
                 0.77 
               
               
                 13 
                 PSFVPATGTRVEGGLS 
                 246 
                 0.76 
               
               
                 13 
                 STCVVWVDAHADINTP 
                 127 
                 0.76 
               
               
                 14 
                 SLDIVETNPMLAETEE 
                 280 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 232 
                 253 
                 236 
                 DCPVHLSYDVDAIDPSFVPATG 
               
               
                 114 
                 136 
                 132 
                 GTATVSASLVHDPSTCVVWVDAH 
               
               
                 294 
                 314 
                 304 
                 EEHVLDTVSAACAIGRCALGQ 
               
               
                 167 
                 188 
                 176 
                 PPEFSWVPQVLKSNKLVYIGLR 
               
               
                 150 
                 158 
                 153 
                 LHGCPLSFI 
               
               
                 274 
                 285 
                 281 
                 QSGLLQSLDIVE 
               
               
                 79 
                 97 
                 85 
                 NSKIVSESCQKIHDAVKGS 
               
               
                 216 
                 227 
                 217 
                 IGKVVEMALDKV 
               
               
                 206 
                 214 
                 208 
                 FSMYHVDKY 
               
               
                 29 
                 41 
                 35 
                 GVELGPDYILKAG 
               
               
                 4 
                 9 
                 7 
                 IQYKYE 
               
               
                 13 
                 20 
                 18 
                 KASIITAP 
               
               
                 263 
                 272 
                 269 
                 REGLFIAEEI 
               
               
                 100 
                 106 
                 104 
                 EGKLPIT 
               
               
                   
               
            
           
           
               
               
            
               
                 40. IPF6881 
                   
               
               
                 MTKEQLNNDSKNSVVEEEDGGAQFQSYLNNDGIDELTPSVRKHRVSSLSLSDLNQWQNGLTKLSSSTSLSKK 
               
               
                   
               
               
                 NSSSANLKKVDSLAKLSRNASIIKRKKKEIIDHERVASYAFCFDIDGVILRGPDTIPQAVEAMKLLNGENKY 
               
               
                   
               
               
                 HIKVPSIFVTNGGGKPEQQRADDLSKRLNCTITKEQIIQGHTPMKDLVDVYKNVLVVGGVGNVCRNVAESYG 
               
               
                   
               
               
                 FKNVYTPLDIMKWNPAVSPYHDLTEEERVCTKDVDFHKIPIDAIMVFADSRNWAADQQIILELLLSVNGVMG 
               
               
                   
               
               
                 TQSKTFDEGPQIYFAHSDFIWATNYKLSRYGMGALQVSIAALYREHTGKELKVNRFGKPQKGTFKFANKVLS 
               
               
                   
               
               
                 HWRQGVLDEHLKKLSVNDPNANDADILINEDGEEIINQAKLENYNWSDSEDDEDDEDAVNGGSSTAKKALKD 
               
               
                   
               
               
                 VGKIADVGKPDKITLELPPASTVYFVGDTPESDIRFANSHDASWHSILVKTGVYQAGTEPKYKPKHLCNDVL 
               
               
                   
               
               
                 EAVKYAIEREHAMELAEWNETAQDVNEDDKGSRLNFADLVMTPSDKKENDTTEKKPSGVSSTSKSSIAEAEE 
               
               
                   
               
               
                 VEVPDILAAQIEKLKDVSVSK* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 VGKIADVGKPDKITLE 
                 433 
                 0.92 
               
               
                 1 
                 EQIIQGHTPMKDLVDV 
                 179 
                 0.92 
               
               
                 2 
                 ESDIRFANSHDASWHS 
                 463 
                 0.91 
               
               
                 2 
                 LELPPASTVYFVGDTP 
                 447 
                 0.91 
               
               
                 2 
                 PDTIPQAVEAMKLLNG 
                 125 
                 0.91 
               
               
                 3 
                 KKEIIDHERVASYAFC 
                 99 
                 0.89 
               
               
                 3 
                 ADLVMTPSDKKENDTT 
                 541 
                 0.89 
               
               
                 3 
                 REHAMELAEWNETAQD 
                 513 
                 0.89 
               
               
                 3 
                 AVSPYHDLTEEERVCT 
                 232 
                 0.89 
               
               
                 3 
                 KPEQQRADDLSKRLNC 
                 159 
                 0.89 
               
               
                 3 
                 VEEEDGGAQFQSYLNN 
                 15 
                 0.89 
               
               
                 4 
                 GVMGTQSKTFDEGPQI 
                 285 
                 0.88 
               
               
                 5 
                 NETAQDVNEDDKGSRL 
                 523 
                 0.87 
               
               
                 5 
                 YQAGTEPKYKPKHLCN 
                 486 
                 0.87 
               
               
                 5 
                 DEHLKKLSVNDPNAND 
                 368 
                 0.87 
               
               
                 5 
                 GIDELTPSVRKHRVSS 
                 32 
                 0.87 
               
               
                 6 
                 QAKLENYNWSDSEDDE 
                 398 
                 0.86 
               
               
                 7 
                 HSILVKTGVYQAGTEP 
                 477 
                 0.85 
               
               
                 7 
                 YFVGDTPESDIRFANS 
                 456 
                 0.85 
               
               
                 7 
                 DILINEDGEEIINQAK 
                 385 
                 0.85 
               
               
                 7 
                 GKPQKGTFKFANKVLS 
                 345 
                 0.85 
               
               
                 8 
                 CRNVAESYGFKNVYTP 
                 208 
                 0.84 
               
               
                 9 
                 AALYREHTGKELKVNR 
                 328 
                 0.83 
               
               
                 9 
                 EGPQIYFAHSDFIWAT 
                 296 
                 0.83 
               
               
                 10 
                 SGVSSTSKSSIAEAEE 
                 561 
                 0.82 
               
               
                 10 
                 NWSDSEDDEDDEDAVN 
                 405 
                 0.82 
               
               
                 10 
                 TNYKLSRYGMGALQVS 
                 311 
                 0.82 
               
               
                 10 
                 CFDIDGVILRGPDTIP 
                 114 
                 0.82 
               
               
                 11 
                 SDFIWATNYKLSRYGM 
                 305 
                 0.81 
               
               
                 12 
                 KIPIDAIMVFADSRNW 
                 254 
                 0.79 
               
               
                 12 
                 IMKWNPAVSPYHDLTE 
                 226 
                 0.79 
               
               
                 13 
                 GFKNVYTPLDIMKWNP 
                 216 
                 0.78 
               
               
                 14 
                 LVVGGVGNVCRNVAES 
                 199 
                 0.77 
               
               
                 15 
                 KKENDTTEKKPSGVSS 
                 550 
                 0.76 
               
               
                 16 
                 KVDSLAKLSRNASIIK 
                 81 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 189 
                 214 
                 201 
                 KDLVDVYKNVLVVGGVGNVCRNVAES 
               
               
                 272 
                 286 
                 280 
                 DQQIILELLLSVNGV 
               
               
                 105 
                 123 
                 111 
                 HERVASYAFCFDIDGVILR 
               
               
                 321 
                 333 
                 328 
                 GALQVSIAALYRE 
               
               
                 495 
                 510 
                 501 
                 KPKHLCNDVLEAVKYA 
               
               
                 145 
                 154 
                 150 
                 HIKVPSIFVT 
               
               
                 444 
                 460 
                 455 
                 KITLELPPASTVYFVGD 
               
               
                 576 
                 588 
                 580 
                 EVEVPDILAAQIE 
               
               
                 36 
                 53 
                 48 
                 LTPSVRKHRVSSLSLSDL 
               
               
                 474 
                 488 
                 483 
                 ASWHSILVKTGVYQA 
               
               
                 355 
                 377 
                 373 
                 ANKVLSHWRQGVLDEHLKKLSVN 
               
               
                 231 
                 238 
                 234 
                 PAVSPYHD 
               
               
                 217 
                 224 
                 223 
                 FKNVYTPL 
               
               
                 243 
                 265 
                 247 
                 ERVCTKDVDFHKIPIDAIMVFAD 
               
               
                 79 
                 88 
                 85 
                 LKKVDSLAKL 
               
               
                 540 
                 546 
                 541 
                 FADLVMT 
               
               
                 427 
                 440 
                 436 
                 KKALKDVGKIADVG 
               
               
                 299 
                 307 
                 301 
                 QIYFAHSDF 
               
               
                 128 
                 135 
                 131 
                 IPQAVEAM 
               
               
                 60 
                 69 
                 66 
                 LTKLSSSTSL 
               
               
                 12 
                 17 
                 12 
                 NSVVEE 
               
               
                 560 
                 566 
                 562 
                 PSGVSST 
               
               
                   
               
            
           
           
               
               
            
               
                 41. IPF4258 
                   
               
               
                 MSDSVDRVFVKAIATIRALSSRSNYGSLPRPPAENRIKLYGLYKQATEGDVDGVMPRPVGFTAEDEGAKKKW 
               
               
                   
               
               
                 DAWKREQGLSKTEAKKRYVSYLIETMRVYASGTSEARELLNELEYLWEQIKDLPSSDEETDHHHIPLPSRSP 
               
               
                   
               
               
                 TFSQTDRFSNRTPSITGARTTGTSNLNNIYSHSRRNTTLSLNEYVQQQRMQHQNQQQLHDTTSQPGAPVGGG 
               
               
                   
               
               
                 GGGGGSIYSLPGRMGANNVIEDFKNWQSEVNMVINKLTREFVNSRREVQGNENGDPSTGDRDEELDDVEIIK 
               
               
                   
               
               
                 RRIIHILKFVGWNALKFLKNFAVSLITFMFIVWCIKKNVHVERTYVKQPTNNANKSKKELIINMVLNTDENK 
               
               
                   
               
               
                 WFIRLLGFINRFIGFV* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 GGGSIYSLPGRMGANN 
                 219 
                 0.95 
               
               
                 2 
                 YGLYKQATEGDVDGVM 
                 40 
                 0.90 
               
               
                 2 
                 HVERTYVKQPTNNANK 
                 328 
                 0.90 
               
               
                 3 
                 SYLIETMRVYASGTSE 
                 92 
                 0.88 
               
               
                 3 
                 RPVGFTAEDEGAKKKW 
                 57 
                 0.88 
               
               
                 3 
                 PVGGGGGGGGSIYSLP 
                 212 
                 0.88 
               
               
                 3 
                 PSITGARTTGTSNLNN 
                 157 
                 0.88 
               
               
                 4 
                 AKKKWDAWKREQGLSK 
                 68 
                 0.87 
               
               
                 5 
                 RVYASGTSEARELLNE 
                 99 
                 0.85 
               
               
                 5 
                 HHHIPLPSRSPTFSQT 
                 134 
                 0.85 
               
               
                 6 
                 QQLHDTTSQPGAPVGG 
                 200 
                 0.83 
               
               
                 6 
                 RSPTFSQTDRFSNRTP 
                 142 
                 0.83 
               
               
                 7 
                 RREVQGNENGDPSTGD 
                 261 
                 0.82 
               
               
                 7 
                 LPSSDEETDHHHIPLP 
                 125 
                 0.82 
               
               
                 8 
                 WEQIKDLPSSDEETDH 
                 119 
                 0.81 
               
               
                 9 
                 PAENRIKLYGLYKQAT 
                 32 
                 0.80 
               
               
                 10 
                 KRRIIHILKFVGWNAL 
                 288 
                 0.79 
               
               
                 10 
                 HSRRNTTLSLNEYVQQ 
                 176 
                 0.79 
               
               
                 10 
                 LNNIYSHSRRNTTLSL 
                 170 
                 0.79 
               
               
                 11 
                 PGRMGANNVIEDFKNW 
                 227 
                 0.78 
               
               
                 12 
                 LSKTEAKKRYVSYLIE 
                 81 
                 0.77 
               
               
                 13 
                 NNVIEDFKNWQSEVNM 
                 233 
                 0.76 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 5 
                 20 
                 11 
                 VDRVFVKAIATIRALS 
               
               
                 289 
                 301 
                 295 
                 RRIIHILKFVGWN 
               
               
                 303 
                 336 
                 321 
                 LKFLKNFAVSLITFMFIVWCIKKNVHVERTYVKQ 
               
               
                 88 
                 103 
                 92 
                 KRYVSYLIETMRVYAS 
               
               
                 134 
                 143 
                 137 
                 HHHIPLPSRS 
               
               
                 38 
                 45 
                 40 
                 KLYGLYKQ 
               
               
                 185 
                 192 
                 186 
                 LNEYVQQQ 
               
               
                 363 
                 373 
                 366 
                 IRLLGFINRFI 
               
               
                 209 
                 214 
                 210 
                 PGAPVG 
               
               
                 56 
                 62 
                 57 
                 PRPVGFT 
               
               
                 26 
                 31 
                 30 
                 GSLPRP 
               
               
                 112 
                 120 
                 114 
                 LNELEYLWE 
               
               
                 246 
                 252 
                 247 
                 VNMVINK 
               
               
                 199 
                 205 
                 199 
                 QQQLHDT 
               
               
                   
               
            
           
           
               
               
            
               
                 42. IPF7489 
                   
               
               
                 MTRYRLTYQLKNIALEFGENDGKYFIQLGHSSTGKILNLSTLPSYLTERKVIIIDSVKSGTGRTPGKDIYSD 
               
               
                   
               
               
                 ILDPLFKELSIEHEYHATKSATSISELASSLKDHKVTIIFISGDTSINEFINSLNDSEKGEIAIFPIPGGTG 
               
               
                   
               
               
                 NSLSLSLNITNPLDAIIRLFSAGTTSPLNLYEVDFPQGSHYLIANELGSPVPSHLKFLVVLSWGFHASLVAD 
               
               
                   
               
               
                 SDTPELRKHGIKRFQLAAHQNLSRDQKYEGDFYINDVELNGPFAYWLVTASQRFEPTFEISPKGDILKDELY 
               
               
                   
               
               
                 VVTFNTQNTQYYIMDIMKEVYDKGSHIKNPNVVYKKLDKNDKIQLKTKNSKPLIQRRFCVDGSIIALPETES 
               
               
                   
               
               
                 HEIYIHVKDNSQHSWKLYIIH* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 GSHIKNPNVVYKKLDK 
                 312 
                 0.95 
               
               
                 2 
                 KVIIIDSVKSGTGRTP 
                 50 
                 0.92 
               
               
                 3 
                 SVKSGTGRTPGKDIYS 
                 56 
                 0.90 
               
               
                 3 
                 ISGDTSINEFINSLND 
                 113 
                 0.90 
               
               
                 4 
                 YIMDIMKEVYDKGSHI 
                 300 
                 0.89 
               
               
                 4 
                 GGTGNSLSLSLNITNP 
                 141 
                 0.89 
               
               
                 5 
                 ELSIEHEYHATKSATS 
                 80 
                 0.86 
               
               
                 5 
                 SHEIYIHVKDNSQHSW 
                 360 
                 0.86 
               
               
                 5 
                 NLSRDQKYEGDFYIND 
                 237 
                 0.86 
               
               
                 6 
                 YQLKNIALEFGENDGK 
                 8 
                 0.84 
               
               
                 6 
                 LVTASQRFEPTFEISP 
                 263 
                 0.84 
               
               
                 7 
                 YFIQLGHSSTGKILNL 
                 24 
                 0.83 
               
               
                 8 
                 SISELASSLKDHKVTI 
                 95 
                 0.82 
               
               
                 9 
                 KGDILKDELYVVTFNT 
                 279 
                 0.80 
               
               
                 9 
                 EPTFEISPKGDILKDE 
                 271 
                 0.80 
               
               
                 9 
                 FSAGTTSPLNLYEVDF 
                 164 
                 0.80 
               
               
                 10 
                 TGKILNLSTLPSYLTE 
                 33 
                 0.79 
               
               
                 10 
                 KGEIAIFPIPGGTGNS 
                 131 
                 0.79 
               
               
                 11 
                 GRTPGKDIYSDILDPL 
                 62 
                 0.78 
               
               
                 11 
                 SLNITNPLDAIIRLFS 
                 150 
                 0.78 
               
               
                 12 
                 DFYINDVELNGPFAYW 
                 247 
                 0.77 
               
               
                 12 
                 DFPQGSHYLIANELGS 
                 178 
                 0.77 
               
               
                 13 
                 RKHGIKRFQLAAHQNL 
                 223 
                 0.75 
               
               
                 13 
                 LVADSDTPELRKHGIK 
                 213 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 192 
                 217 
                 202 
                 GSPVPSHLKFLVVLSWGFHASLVADS 
               
               
                 48 
                 57 
                 54 
                 ERKVIIIDSV 
               
               
                 284 
                 292 
                 289 
                 KDELYVVTF 
               
               
                 361 
                 370 
                 364 
                 HEIYIHVKDN 
               
               
                 260 
                 267 
                 261 
                 AYWLVTAS 
               
               
                 317 
                 324 
                 323 
                 NPNVVYKK 
               
               
                 339 
                 358 
                 350 
                 KPLIQRRFCVDGSIIALPET 
               
               
                 94 
                 114 
                 111 
                 TSISELASSLKDHKVTIIFIS 
               
               
                 134 
                 140 
                 137 
                 IAIFPIP 
               
               
                 171 
                 189 
                 174 
                 PLNLYEVDFPQGSHYLIAN 
               
               
                 146 
                 152 
                 150 
                 SLSLSLN 
               
               
                 36 
                 46 
                 42 
                 ILNLSTLPSYL 
               
               
                 24 
                 31 
                 27 
                 YFIQLGHS 
               
               
                 5 
                 16 
                 7 
                 RLTYQLKNIALE 
               
               
                 156 
                 166 
                 160 
                 PLDAIIRLFSA 
               
               
                 228 
                 237 
                 233 
                 KRFQLAAHQN 
               
               
                 70 
                 90 
                 76 
                 YSDILDPLFKELSIEHEYHAT 
               
               
                   
               
            
           
           
               
               
            
               
                 43. MYO5 
                   
               
               
                 MAIVKRGGRTKTKQQQVPAKSSGGGSSGGIKKAEFDITKKKEVGVSDLTLLSKITDEAINENLHKRFMNDTI 
               
               
                   
               
               
                 YTYIGHVLISVNPFRDLGIYTLENLNKYKGRNRLEVPPHVFAIAESMYYNLKSYGENQCVIISGESGAGKTE 
               
               
                   
               
               
                 AAKQIMQYIANVSVNQDNVEISKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFSEGNYQPIAAHI 
               
               
                   
               
               
                 TNYLLEKQRVVSQITNERNFHIFYQFTKHCPPQYQQMFGIQGPETYVYTSAAKCINVDGVDDAKDFQDTLNA 
               
               
                   
               
               
                 MKIIGLTQQEQDNIFRMLASILWIGNISFVEDENGNAAIRDDSVTNFAAYLLDVNPEILKKAIIEKTIETSH 
               
               
                   
               
               
                 GMRRGSTYHSPLNIVQATAVRDALAKGIYNNLFEWIVERVNISLAGSQQQSSKSIGILDIYGFEIFERNSFE 
               
               
                   
               
               
                 QICINYVNEKLQQIFIQLTLKAEQDEYVQEQIKWTPIDYFNNKVVCDLIEATRPQPGLFAALNDSIKTAHAD 
               
               
                   
               
               
                 SEAADQVFAQRLSMVGASNRHFEDRRGKFIIKHYAGDVTYDVAGMTDKNKDAMLRDLLELVSTSQNSFINQV 
               
               
                   
               
               
                 LFPPDLLTQLTDSRKRPETASDKIKKSANILVDTLSQCTPSYIRTIKPNQTKKPRDYDNQQVLHQIKYLGLK 
               
               
                   
               
               
                 ENVRIRRAGFAYRSTFERFVQRFYLLSPATGYAGDYIWRGDDISAVKEILKSCHIPPSEYQLGTTKVFIKTP 
               
               
                   
               
               
                 ETLFALEDMRDKYWHNMAARIQRAWRRYVKRKEDAAKTIQNAWRIKKHGNQFEQFRDYGNGLLQGRKERRRM 
               
               
                   
               
               
                 SMLGSRAFMGDYLGCNYKSGYGRFIINQVGINESVILSSKGEILLSKFGRSSKRLPRIFIVTKTSIYIIAEV 
               
               
                   
               
               
                 LVEKRLQLQKEFTIPISGINYLGLSTFQDNWVAISLHSPTPTTPDVFINLDFKTELVAQLKKLNPGITIKIG 
               
               
                   
               
               
                 PTIEYQKKPGKFHTVKFIIGAGPEIPNNGDHYKSGTVSVKQGLPASSKNPKRPRGVSSKVDYSKYYNRGAAR 
               
               
                   
               
               
                 KTAAAAQATPRYNQPTPVANSGYSAQPAYPIPQQPQQYQPQQSQQQTPYPTQSSIPSVNQNQSRQPQRKVPP 
               
               
                   
               
               
                 PAPSLQVSAAQAALGKSPTQQRQTPAHNPVASPNRPASTTIATTTSHTSRPVKKTAPAPPVKKTAPPPPPPT 
               
               
                   
               
               
                 LVKPKFPTYKAMFDYDGSVAGSIPLVKDTVYYVTQVNGKWGLVKTMDETKEGWSPIDYLKECSPNETQKSAP 
               
               
                   
               
               
                 PPPPPPPAATASAGANGASNPISTTTSTNTTTSSHTTNATSNGSLGNGLADALKAKKQEETTLAGSLADALK 
               
               
                   
               
               
                 KRQGATRDSDDEEEEDDDDW* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 TKEGWSPIDYLKECSP 
                 1201 
                 0.97 
               
               
                 2 
                 PSEYQLGTTKVFIKTP 
                 705 
                 0.95 
               
               
                 2 
                 EKTIETSHGMRRGSTY 
                 353 
                 0.95 
               
               
                 3 
                 SPTPTTPDVFINLDFK 
                 902 
                 0.93 
               
               
                 4 
                 GKFIIKHYAGDVTYDV 
                 531 
                 0.92 
               
               
                 4 
                 MFGIQGPETYVYTSAA 
                 253 
                 0.92 
               
               
                 4 
                 NQCVIISGESGAGKTE 
                 129 
                 0.92 
               
               
                 5 
                 ARIQRAWRRYVKRKED 
                 739 
                 0.91 
               
               
                 5 
                 AGDVTYDVAGMTDKNK 
                 539 
                 0.91 
               
               
                 5 
                 DENGNAAIRDDSVTNF 
                 320 
                 0.91 
               
               
                 6 
                 PRGVSSKVDYSKYYNR 
                 989 
                 0.90 
               
               
                 6 
                 KFIIGAGPEIPNNGDH 
                 952 
                 0.90 
               
               
                 6 
                 GPTIEYQKKPGKFHTV 
                 936 
                 0.90 
               
               
                 6 
                 GITIKIGPTIEYQKKP 
                 930 
                 0.90 
               
               
                 6 
                 AAHITNYLLEKQRVVS 
                 213 
                 0.90 
               
               
                 7 
                 EATRPQPGLFAALNDS 
                 482 
                 0.89 
               
               
                 7 
                 GFEIFERNSFEQICIN 
                 422 
                 0.89 
               
               
                 8 
                 AKTIQNAWRIKKHGNQ 
                 756 
                 0.88 
               
               
                 8 
                 PATGYAGDYIWRGDDI 
                 676 
                 0.88 
               
               
                 8 
                 TPSYIRTIKPNQTKKP 
                 615 
                 0.88 
               
               
                 8 
                 AKCINVDGVDDAKDFQ 
                 268 
                 0.88 
               
               
                 8 
                 SGESGAGKTEAAKQIM 
                 135 
                 0.88 
               
               
                 8 
                 PVKKTAPAPPVKKTAP 
                 1131 
                 0.88 
               
               
                 9 
                 KRPETASDKIKKSANI 
                 591 
                 0.87 
               
               
                 9 
                 VQEQIKWTPIDYFNNK 
                 460 
                 0.87 
               
               
                 9 
                 QGATRDSDDEEEEDDD 
                 1299 
                 0.87 
               
               
                 9 
                 TASAGANGASNPISTT 
                 1234 
                 0.87 
               
               
                 9 
                 YLKECSPNETQKSAPP 
                 1210 
                 0.87 
               
               
                 10 
                 FGRSSKRLPRIFIVTK 
                 840 
                 0.86 
               
               
                 10 
                 HVLISVNPFRDLGIYT 
                 78 
                 0.86 
               
               
                 10 
                 QIMQYIANVSVNQDNV 
                 148 
                 0.86 
               
               
                 10 
                 YKAMFDYDGSVAGSIP 
                 1161 
                 0.86 
               
               
                 10 
                 QQSQQQTPYPTQSSIP 
                 1049 
                 0.86 
               
               
                 11 
                 NDTIYTYIGHVLISVN 
                 69 
                 0.85 
               
               
                 11 
                 KAEQDEYVQEQIKWTP 
                 453 
                 0.85 
               
               
                 11 
                 TSTNTTTSSHTTNATS 
                 1250 
                 0.85 
               
               
                 11 
                 AQAALGKSPTQQRQTP 
                 1090 
                 0.85 
               
               
                 11 
                 QQPQQYQPQQSQQQTP 
                 1041 
                 0.85 
               
               
                 11 
                 NSGYSAQPAYPIPQQP 
                 1028 
                 0.85 
               
               
                 12 
                 KSCHIPPSEYQLGTTK 
                 699 
                 0.84 
               
               
                 12 
                 LQQIFIQLTLKAEQDE 
                 443 
                 0.84 
               
               
                 12 
                 AGSQQQSSKSIGILDI 
                 405 
                 0.84 
               
               
                 12 
                 AKKQEETTLAGSLADA 
                 1279 
                 0.84 
               
               
                 12 
                 SAPPPPPPPPAATASA 
                 1222 
                 0.84 
               
               
                 12 
                 VKKTAPPPPPPTLVKP 
                 1141 
                 0.84 
               
               
                 12 
                 ATTTSHTSRPVKKTAP 
                 1122 
                 0.84 
               
               
                 12 
                 AAAAQATPRYNQPTPV 
                 1011 
                 0.84 
               
               
                 13 
                 VDYSKYYNRGAARKTA 
                 996 
                 0.83 
               
               
                 13 
                 GDHYKSGTVSVKQGLP 
                 965 
                 0.83 
               
               
                 13 
                 GPEIPNNGDHYKSGTV 
                 958 
                 0.83 
               
               
                 13 
                 KPGKFHTVKFIIGAGP 
                 944 
                 0.83 
               
               
                 13 
                 LGCNYKSGYGRFIINQ 
                 805 
                 0.83 
               
               
                 13 
                 PNQTKKPRDYDNQQVL 
                 624 
                 0.83 
               
               
                 13 
                 SFEQICINYVNEKLQQ 
                 430 
                 0.83 
               
               
                 13 
                 KHCPPQYQQMFGIQGP 
                 244 
                 0.83 
               
               
                 13 
                 AKSSGGGSSGGIKKAE 
                 19 
                 0.83 
               
               
                 13 
                 WGLVKTMDETKEGWSP 
                 1192 
                 0.83 
               
               
                 14 
                 GLPASSKNPKRPRGVS 
                 978 
                 0.82 
               
               
                 14 
                 DEAINENLHKRFMNDT 
                 56 
                 0.82 
               
               
                 14 
                 SHGMRRGSTYHSPLNI 
                 359 
                 0.82 
               
               
                 14 
                 AGSLADALKKRQGATR 
                 1288 
                 0.82 
               
               
                 14 
                 PTQQRQTPAHNPVASP 
                 1098 
                 0.82 
               
               
                 15 
                 DVAGMTDKNKDAMLRD 
                 545 
                 0.81 
               
               
                 15 
                 MVLATNPLLESFGCAK 
                 171 
                 0.81 
               
               
                 15 
                 ESMYYNLKSYGENQCV 
                 117 
                 0.81 
               
               
                 16 
                 ENLNKYKGRNRLEVPP 
                 95 
                 0.80 
               
               
                 16 
                 LNIVQATAVRDALAKG 
                 372 
                 0.80 
               
               
                 16 
                 SSGGIKKAEFDITKKK 
                 26 
                 0.80 
               
               
                 17 
                 PETLFALEDMRDKYWH 
                 720 
                 0.79 
               
               
                 17 
                 KVFIKTPETLFALEDM 
                 714 
                 0.79 
               
               
                 17 
                 AIVKRGGRTKTKQQQV 
                 2 
                 0.79 
               
               
                 17 
                 NVEISKIKDMVLATNP 
                 162 
                 0.79 
               
               
                 17 
                 ASNPISTTTSTNTTTS 
                 1242 
                 0.79 
               
               
                 17 
                 IPLVKDTVYYVTQVNG 
                 1175 
                 0.79 
               
               
                 17 
                 YPTQSSIPSVNQNQSR 
                 1057 
                 0.79 
               
               
                 18 
                 EFDITKKKEVGVSDLT 
                 34 
                 0.78 
               
               
                 18 
                 LWIGNISFVEDENGNA 
                 310 
                 0.78 
               
               
                 18 
                 TLVKPKFPTYKAMFDY 
                 1152 
                 0.78 
               
               
                 18 
                 PVASPNRPASTTIATT 
                 1109 
                 0.78 
               
               
                 19 
                 MSMLGSRAFMGDYLGC 
                 792 
                 0.77 
               
               
                 19 
                 HGKYLEIKFSEGNYQP 
                 196 
                 0.77 
               
               
                 20 
                 GTVSVKQGLPASSKNP 
                 971 
                 0.76 
               
               
                 20 
                 AKTLRNNNSSRHGKYL 
                 185 
                 0.76 
               
               
                 20 
                 TVYYVTQVNGKWGLVK 
                 1181 
                 0.76 
               
               
                 20 
                 PSVNQNQSRQPQRKVP 
                 1064 
                 0.76 
               
               
                 20 
                 PRYNQPTPVANSGYSA 
                 1018 
                 0.76 
               
               
                 21 
                 GDYIWRGDDISAVKEI 
                 682 
                 0.75 
               
               
                 21 
                 SKSIGILDIYGFEIFE 
                 412 
                 0.75 
               
               
                 21 
                 NRGAARKTAAAAQATP 
                 1003 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 1168 
                 1188 
                 1185 
                 DGSVAGSIPLVKDTVYYVTQV 
               
               
                 474 
                 481 
                 478 
                 NKVVCDLI 
               
               
                 845 
                 890 
                 863 
                 KRLPRIFIVTKTSIYIIAEVLVEKRLQLQKEFTIPISGINY 
               
               
                   
                   
                   
                 LGLST 
               
               
                 73 
                 86 
                 80 
                 YTYIGHVLISVNPF 
               
               
                 106 
                 118 
                 111 
                 LEVPPHVFAIAES 
               
               
                 432 
                 442 
                 436 
                 EQICINYVNEK 
               
               
                 333 
                 345 
                 339 
                 TNFAAYLLDVNPE 
               
               
                 665 
                 679 
                 671 
                 ERFVQRFYLLSPATG 
               
               
                 691 
                 709 
                 700 
                 ISAVKEILKSCHIPPSEYQ 
               
               
                 128 
                 135 
                 133 
                 ENQCVIIS 
               
               
                 635 
                 648 
                 641 
                 NQQVLHQIKYLGLK 
               
               
                 894 
                 903 
                 899 
                 NWVAISLHSP 
               
               
                 368 
                 383 
                 377 
                 YHSPLNIVQATAVRDA 
               
               
                 573 
                 586 
                 579 
                 INQVLFPPDLLTQL 
               
               
                 148 
                 161 
                 155 
                 QIMQYIANVSVNQD 
               
               
                 42 
                 53 
                 48 
                 EVGVSDLTLLSK 
               
               
                 559 
                 568 
                 564 
                 RDLLELVSTS 
               
               
                 1075 
                 1097 
                 1084 
                 QRKVPPPAPSLQVSAAQAALGKS 
               
               
                 603 
                 621 
                 611 
                 SANILVDTLSQCTPSYIRT 
               
               
                 970 
                 982 
                 976 
                 SGTVSVKQGLPAS 
               
               
                 259 
                 276 
                 273 
                 PETYVYTSAAKCINVDGV 
               
               
                 237 
                 251 
                 248 
                 HIFYQFTKHCPPQYQ 
               
               
                 210 
                 230 
                 227 
                 QPIAAHITNYLLEKQRVVSQI 
               
               
                 917 
                 927 
                 923 
                 KTELVAQLKKL 
               
               
                 444 
                 453 
                 449 
                 QQIFIQLTLK 
               
               
                 1129 
                 1162 
                 1151 
                 SRPVKKTAPAPPVKKTAPPPPPPTLVKPKFPTYK 
               
               
                 304 
                 313 
                 309 
                 RMLASILWIG 
               
               
                 823 
                 840 
                 829 
                 INESVILSSKGEILLSKF 
               
               
                 989 
                 1001 
                 995 
                 PRGVSSKVDYSKY 
               
               
                 169 
                 187 
                 181 
                 KDMVLATNPLLESFGCAKT 
               
               
                 948 
                 958 
                 952 
                 FHTVKFIIGAG 
               
               
                 508 
                 519 
                 513 
                 ADQVFAQRLSMV 
               
               
                 1207 
                 1214 
                 1213 
                 PIDYLKEC 
               
               
                 487 
                 496 
                 491 
                 QPGLFAALND 
               
               
                 533 
                 547 
                 536 
                 FIIKHYAGDVTYDVA 
               
               
                 1053 
                 1067 
                 1063 
                 QQTPYPTQSSIPSVN 
               
               
                 907 
                 914 
                 913 
                 TPDVFINL 
               
               
                 410 
                 424 
                 418 
                 QSSKSIGILDIYGFE 
               
               
                 1032 
                 1051 
                 1036 
                 SAQPAYPIPQQPQQYQPQQS 
               
               
                 394 
                 408 
                 399 
                 EWIVERVNISLAGSQ 
               
               
                 804 
                 810 
                 807 
                 YLGCNYK 
               
               
                 1107 
                 1113 
                 1108 
                 HNPVASP 
               
               
                 457 
                 463 
                 462 
                 DEYVQEQ 
               
               
                 1274 
                 1279 
                 1276 
                 ADALKA 
               
               
                 14 
                 20 
                 16 
                 QQQVPAK 
               
               
                 720 
                 726 
                 723 
                 PETLFAL 
               
               
                 711 
                 718 
                 717 
                 GTTKVFIK 
               
               
                 1222 
                 1236 
                 1226 
                 SAPPPPPPPPAATAS 
               
               
                 197 
                 203 
                 202 
                 GKYLEIK 
               
               
                 1288 
                 1294 
                 1293 
                 AGSLADA 
               
               
                 1023 
                 1029 
                 1023 
                 PTPVANS 
               
               
                 1012 
                 1017 
                 1013 
                 AAAQAT 
               
               
                   
               
            
           
           
               
               
            
               
                 44. PRA1 
                   
               
               
                 MNYLLFCLFFAFSVAAPVTVTRFVDASPTGYDWRADWVKGFPIDSSCNATQYNQLSTGLQEAQLLAEHARDH 
               
               
                   
               
               
                 TLRFGSKSPFFRKYFGNDTASAEVVGHFENVVGADKSSILFLCDDLDDKCKNDGWAGYWRGSNHSDQTIICD 
               
               
                   
               
               
                 LSFVTRRYLSQLCSGGYTVSKSKTNIFWAGDLLHRFWHLKSIGQLVIEHYADTYEEVLELAQENSTYAVRNS 
               
               
                   
               
               
                 NSLIYYALDVYAYDVTIPGEGCNGDGTSYKKSDFSSFEDSDSGSDSGASSTASSSHQHTDSNPSATTDANSH 
               
               
                   
               
               
                 CHTHADGEVHC* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 AYDVTIPGEGCNGDGT 
                 228 
                 0.90 
               
               
                 2 
                 DWVKGFPIDSSCNATQ 
                 36 
                 0.89 
               
               
                 2 
                 SQLCSGGYTVSKSKTN 
                 154 
                 0.89 
               
               
                 2 
                 DQTIICDLSFVTRRYL 
                 138 
                 0.89 
               
               
                 2 
                 KNDGWAGYWRGSNHSD 
                 123 
                 0.89 
               
               
                 3 
                 TRFVDASPTGYDWRAD 
                 21 
                 0.88 
               
               
                 4 
                 NSLIYYALDVYAYDVT 
                 217 
                 0.87 
               
               
                 5 
                 GEGCNGDGTSYKKSDF 
                 235 
                 0.86 
               
               
                 6 
                 HQHTDSNPSATTDANS 
                 272 
                 0.85 
               
               
                 7 
                 SPTGYDWRADWVKGFP 
                 27 
                 0.84 
               
               
                 7 
                 LELAQENSTYAVRNSN 
                 202 
                 0.84 
               
               
                 8 
                 EHARDHTLRFGSKSPF 
                 67 
                 0.83 
               
               
                 9 
                 SSFEDSDSGSDSGASS 
                 251 
                 0.82 
               
               
                 10 
                 DGTSYKKSDFSSFEDS 
                 241 
                 0.81 
               
               
                 10 
                 GQLVIEHYADTYEEVL 
                 187 
                 0.81 
               
               
                 11 
                 YWRGSNHSDQTIICDL 
                 130 
                 0.80 
               
               
                 12 
                 SSTASSSHQHTDSNPS 
                 265 
                 0.79 
               
               
                 13 
                 AFSVAAPVTVTRFVDA 
                 11 
                 0.77 
               
               
                 14 
                 LRFGSKSPFFRKYFGN 
                 74 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 4 
                 27 
                 6 
                 LLFCLFFAFSVAAPVTVTRFVDAS 
               
               
                 109 
                 121 
                 112 
                 SSILFLCDDLDDK 
               
               
                 139 
                 165 
                 145 
                 QTIICDLSFVTRRYLSQLCSGGYTVSK 
               
               
                 218 
                 236 
                 221 
                 SLIYYALDVYAYDVTIPGE 
               
               
                 173 
                 196 
                 192 
                 AGDLLHRFWHLKSIGQLVIEHYAD 
               
               
                 93 
                 107 
                 97 
                 SAEVVGHFENVVGAD 
               
               
                 286 
                 292 
                 290 
                 NSHCHTH 
               
               
                 61 
                 68 
                 62 
                 EAQLLAEH 
               
               
                 198 
                 205 
                 203 
                 YEEVLELA 
               
               
                 43 
                 50 
                 44 
                 IDSSCNAT 
               
               
                 267 
                 274 
                 271 
                 TASSSHQH 
               
               
                   
               
            
           
           
               
               
            
               
                 45. AMYG2 
                   
               
               
                 MKLFLTIIFIIASVNAVKEYLFKSCSQSGFCNRNRHYATEVSNCENFQSPYSIDSIKVDNDTITGVVFKHLP 
               
               
                   
               
               
                 QLDHPIQFPFEISILEGNFRFKLTEKENLVAKNVNPVRYNETEKWAFKQGVTKSSDFDVSLRDNEARVIYGD 
               
               
                   
               
               
                 HEVLIQYHPIMFVFKYAGKEQLRINDKQFLNIEHRRTRDENDNNMLPQESDFNMFSDSFQDSKFDTLPLGPE 
               
               
                   
               
               
                 SIGLDFTLLGFSNLYGIPEHADSLLLRDTSSGEPYRLYNVDIFEYEPNSRLPMYGSIPLVVAAKPDVSIGIF 
               
               
                   
               
               
                 WLNSADTYVDIHKSKSSTVHWMSENGILDFIVIIEKSPAMVNSQYGKVTGNTQLPPLFSLGYHQCRWNYNDE 
               
               
                   
               
               
                 KDVLDVHAKFDEYEIPYDTIWLDIEYTDEKKYFTWHKENFATPEKMLRELDRTGRNLVAIIDPHIKTGYDVS 
               
               
                   
               
               
                 DEIIKKGLTMKDSNNNTYYGHCWPGESVWIDTLNPNSQSFWDKKHKQFMTPAPNIHLWNDMNEPSVFNGPET 
               
               
                   
               
               
                 SAPKDNLHFGQWEHRSIHNVFGLSYHETTFNSLLNRSPEKRPFILTRSYFAGSQRTAAMWTGDNMSKWEYLK 
               
               
                   
               
               
                 ISIPMVLTSNVVGMPFAGADVGGFFGNPSSELLTRWYQAGIWYPFFRAHAHIDSRRREPWLAGEPYTQYIRD 
               
               
                   
               
               
                 AIRLRYALLPLFYTSFYEASKTGTPVIKPVFYENTHNADSYAIDDEFFIGNSGLLVKPVTDEGAKEIEFYLP 
               
               
                   
               
               
                 DDKVYYDFTNGVLQGVYKGGKKPVQLSDIPMLLKGGSIIPMKTRYRRSSKLMKSDPYTLVIALDEEGSASGK 
               
               
                   
               
               
                 LYVDDGETFAQGTEVAFTVDNNIINAKKIGPTASIPIEKIIIASKDQTTTLNNPKLDINSDWSLPFSFDSHR 
               
               
                   
               
               
                 KIEHDEL* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 FGLSYHETTFNSLLNR 
                 525 
                 0.93 
               
               
                 2 
                 YQAGIWYPFFRAHAHI 
                 613 
                 0.92 
               
               
                 2 
                 NNTYYGHCWPGESVWI 
                 447 
                 0.92 
               
               
                 2 
                 DEIIKKGLTMKDSNNN 
                 433 
                 0.92 
               
               
                 2 
                 YEIPYDTIWLDIEYTD 
                 373 
                 0.92 
               
               
                 3 
                 EKIIIASKDQTTTLNN 
                 830 
                 0.91 
               
               
                 3 
                 IEHRRTRDENDNNMLP 
                 176 
                 0.91 
               
               
                 4 
                 GGSIIPMKTRYRRSSK 
                 755 
                 0.90 
               
               
                 4 
                 AGEPYTQYIRDAIRLR 
                 638 
                 0.90 
               
               
                 5 
                 NSDWSLPFSFDSHRKI 
                 851 
                 0.88 
               
               
                 5 
                 KHKQFMTPAPNIHLWN 
                 476 
                 0.88 
               
               
                 5 
                 CSQSGFCNRNRHYATE 
                 25 
                 0.88 
               
               
                 5 
                 TSSGEPYRLYNVDIFE 
                 245 
                 0.88 
               
               
                 6 
                 AKEIEFYLPDDKVYYD 
                 712 
                 0.87 
               
               
                 7 
                 QGTEVAFTVDNNIINA 
                 803 
                 0.86 
               
               
                 7 
                 GTPVIKPVFYENTHNA 
                 671 
                 0.86 
               
               
                 7 
                 TSFYEASKTGTPVIKP 
                 662 
                 0.86 
               
               
                 7 
                 TGDNMSKWEYLKISIP 
                 565 
                 0.86 
               
               
                 7 
                 HQCRWNYNDEKDVLDV 
                 351 
                 0.86 
               
               
                 8 
                 TRSYFAGSQRTAAMWT 
                 550 
                 0.85 
               
               
                 8 
                 IVIIEKSPAMVNSQYG 
                 319 
                 0.85 
               
               
                 9 
                 EGSASGKLYVDDGETF 
                 786 
                 0.84 
               
               
                 9 
                 EVLIQYHPIMFVFKYA 
                 146 
                 0.84 
               
               
                 10 
                 PSVFNGPETSAPKDNL 
                 496 
                 0.83 
               
               
                 10 
                 VAIIDPHIKTGYDVSD 
                 418 
                 0.83 
               
               
                 10 
                 VNSQYGKVTGNTQLPP 
                 329 
                 0.83 
               
               
                 11 
                 HAHIDSRRREPWLAGE 
                 625 
                 0.82 
               
               
                 11 
                 TPEKMLRELDRTGRNL 
                 402 
                 0.82 
               
               
                 12 
                 GPTASIPIEKIIIASK 
                 822 
                 0.81 
               
               
                 12 
                 CENFQSPYSIDSIKVD 
                 44 
                 0.81 
               
               
                 12 
                 FWLNSADTYVDIHKSK 
                 288 
                 0.81 
               
               
                 12 
                 NETEKWAFKQGVTKSS 
                 112 
                 0.81 
               
               
                 13 
                 QGVYKGGKKPVQLSDI 
                 734 
                 0.80 
               
               
                 13 
                 IHLWNDMNEPSVFNGP 
                 487 
                 0.80 
               
               
                 13 
                 PQESDFNMFSDSFQDS 
                 191 
                 0.80 
               
               
                 14 
                 KLMKSDPYTLVIALDE 
                 770 
                 0.79 
               
               
                 14 
                 GMPFAGADVGGFFGNP 
                 589 
                 0.79 
               
               
                 14 
                 PGESVWIDTLNPNSQS 
                 456 
                 0.79 
               
               
                 15 
                 FLTIIFIIASVNAVKE 
                 4 
                 0.78 
               
               
                 15 
                 TGNTQLPPLFSLGYHQ 
                 337 
                 0.78 
               
               
                 16 
                 DVHAKFDEYEIPYDTI 
                 365 
                 0.77 
               
               
                 16 
                 YGIPEHADSLLLRDTS 
                 231 
                 0.77 
               
               
                 17 
                 FKLTEKENLVAKNVNP 
                 93 
                 0.76 
               
               
                 17 
                 EFFIGNSGLLVKPVTD 
                 694 
                 0.76 
               
               
                 17 
                 DVGGFFGNPSSELLTR 
                 596 
                 0.76 
               
               
                 17 
                 PMVLTSNVVGMPFAGA 
                 580 
                 0.76 
               
               
                 17 
                 TWHKENFATPEKMLRE 
                 394 
                 0.76 
               
               
                 17 
                 DEKKYFTWHKENFATP 
                 388 
                 0.76 
               
               
                 17 
                 IWLDIEYTDEKKYFTW 
                 380 
                 0.76 
               
               
                 17 
                 RHYATEVSNCENFQSP 
                 35 
                 0.76 
               
               
                 17 
                 KQGVTKSSDFDVSLRD 
                 120 
                 0.76 
               
               
                 18 
                 PVFYENTHNADSYAID 
                 677 
                 0.75 
               
               
                 18 
                 SQRTAAMWTGDNMSKW 
                 557 
                 0.75 
               
               
                 18 
                 PMYGSIPLVVAAKPDV 
                 268 
                 0.75 
               
               
                 18 
                 FEYEPNSRLPMYGSIP 
                 259 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 268 
                 290 
                 276 
                 PMYGSIPLVVAAKPDVSIGIFWL 
               
               
                 64 
                 88 
                 69 
                 TGVVFKHLPQLDHPIQFPFEISILE 
               
               
                 776 
                 783 
                 780 
                 PYTLVIAL 
               
               
                 699 
                 707 
                 705 
                 NSGLLVKPV 
               
               
                 671 
                 681 
                 677 
                 GTPVIKPVFYE 
               
               
                 651 
                 667 
                 657 
                 RLRYALLPLFYTSFYEA 
               
               
                 139 
                 160 
                 150 
                 RVIYGDHEVLIQYHPIMFVFKY 
               
               
                 573 
                 591 
                 585 
                 EYLKISIPMVLTSNVVGMP 
               
               
                 316 
                 324 
                 318 
                 LDFIVIIEK 
               
               
                 4 
                 30 
                 11 
                 FLTIIFIIASVNAVKEYLFKSCSQSGF 
               
               
                 729 
                 739 
                 735 
                 TNGVLQGVYKG 
               
               
                 342 
                 354 
                 345 
                 LPPLFSLGYHQCR 
               
               
                 362 
                 370 
                 366 
                 DVLDVHAKF 
               
               
                 416 
                 424 
                 420 
                 NLVAIIDPH 
               
               
                 521 
                 531 
                 527 
                 IHNVFGLSYHE 
               
               
                 236 
                 244 
                 239 
                 HADSLLLRD 
               
               
                 742 
                 757 
                 746 
                 KPVQLSDIPMLLKGGS 
               
               
                 250 
                 260 
                 256 
                 PYRLYNVDIFE 
               
               
                 790 
                 796 
                 792 
                 SGKLYVD 
               
               
                 451 
                 457 
                 453 
                 YGHCWPG 
               
               
                 293 
                 302 
                 299 
                 ADTYVDIHKS 
               
               
                 804 
                 810 
                 808 
                 GTEVAFT 
               
               
                 100 
                 109 
                 103 
                 NLVAKNVNPV 
               
               
                 715 
                 727 
                 721 
                 IEFYLPDDKVYYD 
               
               
                 49 
                 56 
                 50 
                 SPYSIDSI 
               
               
                 209 
                 234 
                 227 
                 DTLPLGPESIGLDFTLLGFSNLYGIP 
               
               
                 38 
                 44 
                 39 
                 ATEVSNC 
               
               
                 128 
                 134 
                 130 
                 DFDVSLR 
               
               
                 614 
                 628 
                 625 
                 QAGIWYPFFRAHAHI 
               
               
                 823 
                 836 
                 831 
                 PTASIPIEKIIIAS 
               
               
                 545 
                 552 
                 550 
                 RPFILTRS 
               
               
                 855 
                 861 
                 857 
                 SLPFSFD 
               
               
                 606 
                 612 
                 611 
                 SELLTRW 
               
               
                 428 
                 434 
                 434 
                 GYDVSDE 
               
               
                 642 
                 649 
                 644 
                 YTQYIRDA 
               
               
                 373 
                 385 
                 383 
                 YEIPYDTIWLDIE 
               
               
                 326 
                 335 
                 334 
                 PAMVNSQYGK 
               
               
                   
               
            
           
           
               
               
            
               
                 46. LP19 
                   
               
               
                 MTSTDEDSGKNQFSTPKAQQLSTNGSFPLIDQKTKPQLDMEKMRDILVEETCLYTKGVQDTDVDWFITDSSI 
               
               
                   
               
               
                 DPNADVQPSVNSPRETNLNSQATIPTSHLTSAISNSNENYTNKTKPSIAPIQEENIASETSPRHHRHEIEQQ 
               
               
                   
               
               
                 QPRRRSSVSVSPSGGFLSKLKSKFHKESPTPPGNHQDGLFKSGYSVNPDKKSNDSSNSSIASLSSSPRLVSG 
               
               
                   
               
               
                 SNLQRTMSTPAYTHDTCDPRLEEYIKFYRKSDRRASVASSSHSAKDECLPSVLVNASEPTNYNKXKDZVNAS 
               
               
                   
               
               
                 RVSGFFXRKXSVAMKNXETSSXRSXVSVSVTPQSQVKNGLENNPSFQGLKPLKRVAFHSSTXLIDPPQQIPS 
               
               
                   
               
               
                 RTPRKGNVEVLPNGTVNIRPLTDEERLEIEKSQKGLGGGIVVGGTGALGYIKKDSDPPKPGENNLNAQDDDN 
               
               
                   
               
               
                 NDDGSNQSSESSQLESEPSVDKHAKSFTIDTPMARHQAVNYSVPIKKMALDTMYARCCHLREILPIPAILKQ 
               
               
                   
               
               
                 IPKGSMAPIPVLQLRNPTPTMIEIQSFADFLRIAPVICVSLDGVNFSVEQFKILLSAMSAKKQLEKLSLRNT 
               
               
                   
               
               
                 PIDQKGWSLLCWFLSRNTVLNRLDITQCPSLSVNTLKKKKKKTDSKFDETLVRMVSNKDNRSDVDWELFVAT 
               
               
                   
               
               
                 LVARGGIEELILTGCCITDIEIFEKLISLAVSKKTSRLGLAFNQLTSRHMKIIVDEWLFKDFARGIDFGYND 
               
               
                   
               
               
                 FSSVHMLKILVDYSKRPDFDQILSKSTLSFVSLNSTNVSLGDIFKESFERVLMKLPNLKYVDFSNNQRLFGT 
               
               
                   
               
               
                 FGKSDNEEADANEVASVNYFISKLPLFPKLVRLHLENENFSKSSVLQIAEILPFCKSLGYFSILGSKLDFTC 
               
               
                   
               
               
                 GSALVNAVKNSQSLINVDADSDNFPDIFKERMGLYTMRNMERLLYSAKKADVKTPLLSEDSAGNVSMTEQLH 
               
               
                   
               
               
                 EILRLKSQQKLDLQSPEITKFIERAKSISHGLRQTINELLRMQLKNRLDLDGKETLIRLIFIDSSIEKGLML 
               
               
                   
               
               
                 IDPSLVDDNNKNAGYLTSMIGTREGNEETQQFEQSDHLDPQPAASVLANKSPSVMSRSDSRTSLNNLNKEEG 
               
               
                   
               
               
                 SVLKLAKLRDFHSPNSPYPESTGEELRNKLMSVELADLDKVIDFLSDLKKKGVSLEKVFQCHENQGANDHEE 
               
               
                   
               
               
                 GLLDIEHIKSRLQKLSVEQMDGVSKDVDTDADEINTGTDKTHTLNNTYDEVLKNLFK 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 SFTIDTPMARHQAVNY 
                 457 
                 0.94 
               
               
                 1 
                 LMLIDPSLVDDNNKNA 
                 1005 
                 0.94 
               
               
                 2 
                 PIKKMALDTMYARCCH 
                 475 
                 0.93 
               
               
                 2 
                 QIPSRTPRKGNVEVLP 
                 356 
                 0.93 
               
               
                 2 
                 STXLIDPPQQIPSRTP 
                 347 
                 0.93 
               
               
                 2 
                 ADEINTGTDKTHTLNN 
                 1182 
                 0.93 
               
               
                 3 
                 SVTPQSQVKNGLENNP 
                 316 
                 0.92 
               
               
                 4 
                 TKPSIAPIQEENIASE 
                 116 
                 0.91 
               
               
                 4 
                 CHENQGANDHEEGLLD 
                 1140 
                 0.91 
               
               
                 4 
                 SPSVMSRSDSRTSLNN 
                 1058 
                 0.91 
               
               
                 5 
                 WFITDSSIDPNADVQP 
                 65 
                 0.90 
               
               
                 5 
                 PKGSMAPIPVLQLRNP 
                 505 
                 0.90 
               
               
                 5 
                 EEYIKFYRKSDRRASV 
                 238 
                 0.90 
               
               
                 6 
                 LVDYSKRPDFDQILSK 
                 729 
                 0.89 
               
               
                 6 
                 GYIKKDSDPPKPGENN 
                 408 
                 0.89 
               
               
                 6 
                 LFKSGYSVNPDKKSND 
                 183 
                 0.89 
               
               
                 6 
                 QFEQSDHLDPQPAASV 
                 1038 
                 0.89 
               
               
                 7 
                 TFGKSDNEEADANEVA 
                 791 
                 0.88 
               
               
                 7 
                 STPAYTHDTCDPRLEE 
                 224 
                 0.88 
               
               
                 7 
                 IASETSPRHHRHEIEQ 
                 128 
                 0.88 
               
               
                 7 
                 TSAISNSNENYTNKTK 
                 102 
                 0.88 
               
               
                 8 
                 DILVEETCLYTKGVQD 
                 45 
                 0.87 
               
               
                 8 
                 PRLVSGSNLQRTMSTP 
                 211 
                 0.87 
               
               
                 8 
                 KFHKESPTPPGNHQDG 
                 167 
                 0.87 
               
               
                 9 
                 SVSVSPSGGFLSKLKS 
                 151 
                 0.86 
               
               
                 9 
                 DKTHTLNNTYDEVLKN 
                 1190 
                 0.86 
               
               
                 10 
                 HGLRQTINELLRMQLK 
                 965 
                 0.85 
               
               
                 10 
                 AFNQLTSRHMKIIVDE 
                 688 
                 0.85 
               
               
                 10 
                 SVEQMDGVSKDVDTDA 
                 1167 
                 0.85 
               
               
                 10 
                 YLTSMIGTREGNEETQ 
                 1022 
                 0.85 
               
               
                 11 
                 TMRNMERLLYSAKKAD 
                 899 
                 0.84 
               
               
                 11 
                 SNNQRLFGTFGKSDNE 
                 783 
                 0.84 
               
               
                 12 
                 FKERMGLYTMRNMERL 
                 891 
                 0.83 
               
               
                 12 
                 PKLVRLHLENENFSKS 
                 819 
                 0.83 
               
               
                 12 
                 HQAVNYSVPIKKMALD 
                 467 
                 0.83 
               
               
                 13 
                 GCCITDIEIFEKLISL 
                 661 
                 0.82 
               
               
                 13 
                 ASEPTNYNKXKDVNAS 
                 272 
                 0.82 
               
               
                 13 
                 EIEQQQPRRRSSVSVS 
                 140 
                 0.82 
               
               
                 13 
                 FSTPKAQQLSTNGSFP 
                 13 
                 0.82 
               
               
                 14 
                 PSVLVNASEPTNYNKX 
                 266 
                 0.81 
               
               
                 14 
                 SHSAKDECLPSVLVNA 
                 257 
                 0.81 
               
               
                 14 
                 SNSSIASLSSSPRLVS 
                 200 
                 0.81 
               
               
                 15 
                 LIFIDSSIEKGLMLID 
                 994 
                 0.80 
               
               
                 15 
                 QATIPTSHLTSAISNS 
                 93 
                 0.80 
               
               
                 15 
                 FKESFERVLMKLPNLK 
                 763 
                 0.80 
               
               
                 15 
                 KKKKKTDSKFDETLVR 
                 613 
                 0.80 
               
               
                 15 
                 DFLRIAPVICVSLDGV 
                 532 
                 0.80 
               
               
                 15 
                 LQLRNPTPTMIEIQSF 
                 515 
                 0.80 
               
               
                 15 
                 HLREILPIPAILKQIP 
                 490 
                 0.80 
               
               
                 15 
                 QSSESSQLESEPSVDK 
                 438 
                 0.80 
               
               
                 15 
                 GVSKDVDTDADEINTG 
                 1173 
                 0.80 
               
               
                 16 
                 QKGWSLLCWFLSRNTV 
                 579 
                 0.79 
               
               
                 16 
                 TKGVQDTDVDWFITDS 
                 55 
                 0.79 
               
               
                 16 
                 MIEIQSFADFLRIAPV 
                 524 
                 0.79 
               
               
                 16 
                 EPSVDKHAKSFTIDTP 
                 448 
                 0.79 
               
               
                 16 
                 VGGTGALGYIKKDSDP 
                 401 
                 0.79 
               
               
                 16 
                 DQKTKPQLDMEKMRDI 
                 31 
                 0.79 
               
               
                 16 
                 FFXRKXSVAMKNXETS 
                 292 
                 0.79 
               
               
                 16 
                 GNHQDGLFKSGYSVNP 
                 177 
                 0.79 
               
               
                 16 
                 SVLANKSPSVMSRSDS 
                 1052 
                 0.79 
               
               
                 17 
                 AMSAKKQLEKLSLRNT 
                 560 
                 0.78 
               
               
                 17 
                 LSTNGSFPLIDQKTKP 
                 21 
                 0.78 
               
               
                 17 
                 PYPESTGEELRNKLMS 
                 1096 
                 0.78 
               
               
                 18 
                 TPLLSEDSAGNVSMTE 
                 917 
                 0.77 
               
               
                 18 
                 QSLINVDADSDNFPDI 
                 875 
                 0.77 
               
               
                 18 
                 RGGIEELILTGCCITD 
                 651 
                 0.77 
               
               
                 18 
                 DKVIDFLSDLKKKGVS 
                 1118 
                 0.77 
               
               
                 19 
                 RNTPIDQKGWSLLCWF 
                 573 
                 0.76 
               
               
                 19 
                 IPAILKQIPKGSMAPI 
                 497 
                 0.76 
               
               
                 19 
                 NLNAQDDDNNDDGSNQ 
                 423 
                 0.76 
               
               
                 20 
                 DFTCGSALVNAVKNSQ 
                 860 
                 0.75 
               
               
                 20 
                 ISLAVSKKTSRLGLAF 
                 674 
                 0.75 
               
               
                 20 
                 PSLSVNTLKKKKKKTD 
                 604 
                 0.75 
               
               
                 20 
                 XETSSXRSXVSVSVTP 
                 304 
                 0.75 
               
               
                 20 
                 MTSTDEDSGKNQFSTP 
                 1 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 261 
                 273 
                 267 
                 KDECLPSVLVNAS 
               
               
                 528 
                 562 
                 542 
                 IQSFADFLRIAPVICVSLDGVNFSEQFKILLSAM 
               
               
                 641 
                 653 
                 647 
                 DWELFVATLVARG 
               
               
                 486 
                 505 
                 489 
                 YARCCHLREILPIPAILKQI 
               
               
                 656 
                 668 
                 661 
                 EELILTGCCITDI 
               
               
                 511 
                 519 
                 515 
                 APIPVLQLR 
               
               
                 583 
                 590 
                 587 
                 WSLLCWFL 
               
               
                 601 
                 612 
                 606 
                 ITQCPSLSVNTL 
               
               
                 315 
                 326 
                 317 
                 SVSVTPQSQVKN 
               
               
                 671 
                 682 
                 677 
                 FEKLISLAVSKK 
               
               
                 1080 
                 1091 
                 1085 
                 GSVLKLAKLRDF 
               
               
                 804 
                 826 
                 824 
                 NEVASVNYFISKLPLFPKLVRLH 
               
               
                 834 
                 859 
                 847 
                 KSSVLQIAEILPFCKSLGYFSILGSK 
               
               
                 721 
                 734 
                 730 
                 FSSVHMLKILVDYS 
               
               
                 1005 
                 1014 
                 1011 
                 GLMLIDPSLV 
               
               
                 1130 
                 1144 
                 1138 
                 KKGVSLEKVFQCHEN 
               
               
                 861 
                 872 
                 869 
                 DFTCGSALVNAV 
               
               
                 467 
                 480 
                 474 
                 RHQAVNYSVPIKKM 
               
               
                 992 
                 1000 
                 995 
                 LIRLIFIDS 
               
               
                 45 
                 57 
                 55 
                 DILVEETCLYTKG 
               
               
                 740 
                 763 
                 750 
                 DQILSKSTLSFVSLNSTNVSLGDI 
               
               
                 1045 
                 1063 
                 1053 
                 HLDPQPAASVLANKSPSVM 
               
               
                 149 
                 167 
                 153 
                 RSSVSVSPSGGFLSKLKSK 
               
               
                 769 
                 783 
                 778 
                 ERVLMKLPNLKYVDF 
               
               
                 907 
                 923 
                 919 
                 LLYSAKKADVKTPLLSE 
               
               
                 398 
                 405 
                 399 
                 GGIVVGGT 
               
               
                 75 
                 83 
                 79 
                 NADVQPSVN 
               
               
                 935 
                 952 
                 938 
                 LHEILRLKSQQKLDLQSP 
               
               
                 1152 
                 1170 
                 1166 
                 EGLLDIEHIKSRLQKLSVE 
               
               
                 334 
                 346 
                 343 
                 FQGLKPLKRVAFH 
               
               
                 1110 
                 1128 
                 1123 
                 LMSVELADLDKVIDFLSDL 
               
               
                 367 
                 374 
                 373 
                 NVEVLPNG 
               
               
                 1201 
                 1206 
                 1206 
                 DEVLKN 
               
               
                 202 
                 217 
                 211 
                 SSIASLSSSPRLVSGS 
               
               
                 250 
                 259 
                 255 
                 RASVASSSHS 
               
               
                 698 
                 705 
                 703 
                 MKIIVDEW 
               
               
                 118 
                 123 
                 121 
                 PSIAPI 
               
               
                 95 
                 104 
                 102 
                 TIPTSHLTSA 
               
               
                 185 
                 191 
                 187 
                 KSGYSVN 
               
               
                 27 
                 32 
                 29 
                 FPLIDQ 
               
               
                 227 
                 236 
                 230 
                 AYTHDTCDPR 
               
               
                 354 
                 360 
                 354 
                 PPQQIPS 
               
               
                 443 
                 455 
                 453 
                 SSQLESEPSVDKH 
               
               
                 685 
                 692 
                 687 
                 RLGLAFNQ 
               
               
                 15 
                 21 
                 19 
                 TPKAQQL 
               
               
                 963 
                 969 
                 965 
                 SISHGLR 
               
               
                 238 
                 244 
                 243 
                 EEYIKFY 
               
               
                   
               
            
           
           
               
               
            
               
                 47. ALG5 
                   
               
               
                 MIYYILAFFIFISLSIYATVIFFSHKPRKPFPSELTYKTNDSTDKSHPLPPRINTNSKFQDDGIDISLVIPC 
               
               
                   
               
               
                 YNETQRLGKMLDEAIEYLEKNHQSKYEIIVVDDGSSDGTDEYALQKANEFKLPSHIMRVVQLKQNRGKGGAV 
               
               
                   
               
               
                 THGLLHSRGKYALFADADGATSFPDVAKLVNYLANANGQPSIAIGSRAHMVNTDAVVKRSFIRNFLMYGLHA 
               
               
                   
               
               
                 LVFVFGIRDVRDTQCGFKMFNFEAVKNIFPHMHTERWIFDVEVLLLGEIQKFNMKELPVNWQEIDGSKVDLA 
               
               
                   
               
               
                 RDSIAMAIDLVVTRLAYLLGVYKLDECGRINKKEQ* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 STDKSHPLPPRINTNS 
                 42 
                 0.87 
               
               
                 2 
                 GSKVDLARDSIAMAID 
                 282 
                 0.86 
               
               
                 3 
                 IPCYNETQRLGKMLDE 
                 70 
                 0.85 
               
               
                 4 
                 AMAIDLVVTRLAYLLG 
                 293 
                 0.84 
               
               
                 5 
                 HALVFVFGIRDVRDTQ 
                 215 
                 0.83 
               
               
                 5 
                 DGSSDGTDEYALQKAN 
                 105 
                 0.83 
               
               
                 6 
                 VVTRLAYLLGVYKLDE 
                 299 
                 0.82 
               
               
                 7 
                 GKMLDEAIEYLEKNHQ 
                 80 
                 0.81 
               
               
                 7 
                 SELTYKTNDSTDKSHP 
                 33 
                 0.81 
               
               
                 7 
                 YLLGVYKLDECGRINK 
                 305 
                 0.81 
               
               
                 7 
                 SIAIGSRAHMVNTDAV 
                 185 
                 0.81 
               
               
                 7 
                 HSRGKYALFADADGAT 
                 150 
                 0.81 
               
               
                 7 
                 SLSIYATVIFFSHKPR 
                 13 
                 0.81 
               
               
                 8 
                 KYEIIVVDDGSSDGTD 
                 97 
                 0.80 
               
               
                 9 
                 PHMHTERWIFDVEVLL 
                 246 
                 0.79 
               
               
                 9 
                 TQCGFKMFNFEAVKNI 
                 229 
                 0.79 
               
               
                 9 
                 GGAVTHGLLHSRGKYA 
                 141 
                 0.79 
               
               
                 10 
                 LGEIQKFNMKELPVNW 
                 262 
                 0.78 
               
               
                 11 
                 HMVNTDAVVKRSFIRN 
                 193 
                 0.77 
               
               
                 12 
                 RVVQLKQNRGKGGAVT 
                 130 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 211 
                 224 
                 217 
                 MYGLHALVFVFGIR 
               
               
                 65 
                 74 
                 70 
                 DISLVIPCYN 
               
               
                 254 
                 265 
                 260 
                 IFDVEVLLLGEI 
               
               
                 293 
                 315 
                 306 
                 AMAIDLVVTRLAYLLGVYKLDEC 
               
               
                 4 
                 26 
                 5 
                 YILAFFIFISLSIYATVIFFSHK 
               
               
                 97 
                 105 
                 100 
                 KYEIIVVDD 
               
               
                 167 
                 177 
                 173 
                 FPDVAKLVNYL 
               
               
                 124 
                 135 
                 131 
                 LPSHIMRVVQLK 
               
               
                 143 
                 160 
                 147 
                 AVTHGLLHSRGKYALFAD 
               
               
                 197 
                 204 
                 203 
                 TDAVVKRS 
               
               
                 46 
                 52 
                 50 
                 SHPLPPR 
               
               
                 282 
                 290 
                 285 
                 GSKVDLARD 
               
               
                 185 
                 190 
                 185 
                 SIAIGS 
               
               
                 228 
                 233 
                 229 
                 DTQCGF 
               
               
                 272 
                 277 
                 275 
                 ELPVNW 
               
               
                   
               
            
           
           
               
               
            
               
                 48. HWP1 
                   
               
               
                 MRLSTAQLIAIAYYMLSIGATVPQVDGQGETEEALIQKRSYDYYQEPCDDYPQQQQQQEPCDYPQQQQQEEP 
               
               
                   
               
               
                 CDYPQQQPQEPCDYPQQPQEPCDYPQQPQEPCDYPQQPQEPCDNPPQPDVPCDNPPQPDVPCDNPPQPDIPC 
               
               
                   
               
               
                 DNPPQPDIPCDNPPQPDQPDDNPPIPNIPTDWIPNIPTDWIPDIPEKPTTPATTPNIPATTTTSESSSSSSS 
               
               
                   
               
               
                 SSSSTTPKTSASTTPESSVPATTPNTSVPTTSSESTTPATSPESSVPVTSGSSILATTSESSSAPATTPNTS 
               
               
                   
               
               
                 VPTTTTEAKSSSTPLTTTTEHDTTVVTVTSCSNSVCTESEVTTGVIVITSKDTIYTTYCPLTETTPVSTAPA 
               
               
                   
               
               
                 TETPTGTVSTSTEQSTTVITVTSCSESSCTESEVTTGVVVVTSEETVYTTFCPLTENTPGTDSTPEASIPPM 
               
               
                   
               
               
                 ETIPAGSESSMPAGETSPAVPKSDVPATESAPVPEMTPAGSQPSIPAGETSPAVPKSDVPATESAPAPEMTP 
               
               
                   
               
               
                 AGTETKPAAPKSSAPATEPSPVAPGTESAPAGPGASSSPKSSVLASETSPIAPGAETAPAGSSGAITIPESS 
               
               
                   
               
               
                 AVVSTTEGAIPTTLESVPLMQPSANYSSVAPISTFEGAGNNMRLTFGAAIIGIAAFLI 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 KDTIYTTYCPLTETTP 
                 339 
                 0.97 
               
               
                 1 
                 DVPCDNPPQPDVPCDN 
                 121 
                 0.97 
               
               
                 1 
                 QEPCDNPPQPDVPCDN 
                 111 
                 0.97 
               
               
                 2 
                 DVPCDNPPQPDIPCDN 
                 131 
                 0.96 
               
               
                 3 
                 PGTESAPAGPGASSSP 
                 528 
                 0.95 
               
               
                 3 
                 TETKPAAPKSSAPATE 
                 507 
                 0.95 
               
               
                 3 
                 DIPCDNPPQPDIPCDN 
                 141 
                 0.95 
               
               
                 4 
                 EPSPVAPGTESAPAGP 
                 522 
                 0.93 
               
               
                 4 
                 TFCPLTENTPGTDSTP 
                 410 
                 0.93 
               
               
                 5 
                 EGAIPTTLESVPLMQP 
                 583 
                 0.92 
               
               
                 5 
                 LASETSPIAPGAETAP 
                 548 
                 0.92 
               
               
                 5 
                 SAPATTPNTSVPTTTT 
                 279 
                 0.92 
               
               
                 5 
                 DIPCDNPPQPDQPDDN 
                 151 
                 0.92 
               
               
                 5 
                 QEPCDYPQQPQEPCDN 
                 101 
                 0.92 
               
               
                 6 
                 YDYYQEPCDDYPQQQQ 
                 41 
                 0.91 
               
               
                 6 
                 TSASTTPESSVPATTP 
                 225 
                 0.91 
               
               
                 6 
                 DWIPDIPEKPTTPATT 
                 183 
                 0.91 
               
               
                 7 
                 GETSPAVPKSDVPATE 
                 480 
                 0.89 
               
               
                 7 
                 GETSPAVPKSDVPATE 
                 446 
                 0.89 
               
               
                 7 
                 GSESSMPAGETSPAVP 
                 438 
                 0.89 
               
               
                 7 
                 ENTPGTDSTPEASIPP 
                 416 
                 0.89 
               
               
                 7 
                 SSSSSTTPKTSASTTP 
                 216 
                 0.89 
               
               
                 7 
                 TTPATTPNIPATTTTS 
                 193 
                 0.89 
               
               
                 8 
                 QQQQEEPCDYPQQQPQ 
                 66 
                 0.88 
               
               
                 8 
                 QQQQQEPCDYPQQQQQ 
                 54 
                 0.88 
               
               
                 8 
                 EETVYTTFCPLTENTP 
                 404 
                 0.88 
               
               
                 8 
                 SVPATTPNTSVPTTSS 
                 234 
                 0.88 
               
               
                 9 
                 QEPCDYPQQPQEPCDY 
                 91 
                 0.87 
               
               
                 9 
                 QEPCDYPQQPQEPCDY 
                 81 
                 0.87 
               
               
                 9 
                 SGAITIPESSAVVSTT 
                 567 
                 0.87 
               
               
                 9 
                 METIPAGSESSMPAGE 
                 432 
                 0.87 
               
               
                 10 
                 PATESAPVPEMTPAGS 
                 458 
                 0.86 
               
               
                 10 
                 CPLTETTPVSTAPATE 
                 347 
                 0.86 
               
               
                 10 
                 TSVPTTTTEAKSSSTP 
                 287 
                 0.86 
               
               
                 10 
                 SSESTTPATSPESSVP 
                 248 
                 0.86 
               
               
                 11 
                 TPVSTAPATETPTGTV 
                 353 
                 0.85 
               
               
                 11 
                 AKSSSTPLTTTTEHDT 
                 296 
                 0.85 
               
               
                 11 
                 MLSIGATVPQVDGQGE 
                 15 
                 0.85 
               
               
                 12 
                 APKSSAPATEPSPVAP 
                 513 
                 0.84 
               
               
                 12 
                 QPSIPAGETSPAVPKS 
                 474 
                 0.84 
               
               
                 12 
                 SCTESEVTTGVVVVTS 
                 388 
                 0.84 
               
               
                 12 
                 VIVITSKDTIYTTYCP 
                 333 
                 0.84 
               
               
                 12 
                 TSVPTTSSESTTPATS 
                 242 
                 0.84 
               
               
                 13 
                 APEMTPAGTETKPAAP 
                 499 
                 0.83 
               
               
                 13 
                 TGTVSTSTEQSTTVIT 
                 365 
                 0.83 
               
               
                 14 
                 YPQQQPQEPCDYPQQP 
                 75 
                 0.82 
               
               
                 14 
                 SDVPATESAPAPEMTP 
                 489 
                 0.82 
               
               
                 15 
                 TEHDTTVVTVTSCSNS 
                 307 
                 0.81 
               
               
                 15 
                 SILATTSESSSAPATT 
                 269 
                 0.81 
               
               
                 16 
                 SSVAPISTFEGAGNNM 
                 603 
                 0.80 
               
               
                 17 
                 PPIPNIPTDWIPNIPT 
                 167 
                 0.79 
               
               
                 18 
                 APGAETAPAGSSGAIT 
                 556 
                 0.78 
               
               
                 18 
                 DSTPEASIPPMETIPA 
                 422 
                 0.78 
               
               
                 18 
                 TSESSSSSSSSSSSTT 
                 207 
                 0.78 
               
               
                 19 
                 PEMTPAGSQPSIPAGE 
                 466 
                 0.77 
               
               
                 19 
                 TGVVVVTSEETVYTTF 
                 396 
                 0.77 
               
               
                 19 
                 TSCSESSCTESEVTTG 
                 382 
                 0.77 
               
               
                 20 
                 SVPLMQPSANYSSVAP 
                 592 
                 0.75 
               
               
                 20 
                 QPDQPDDNPPIPNIPT 
                 159 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 311 
                 327 
                 316 
                 TTVVTVTSCSNSVCTES 
               
               
                 395 
                 406 
                 400 
                 TTGVVVVTSEET 
               
               
                 376 
                 392 
                 381 
                 TTVITVTSCSESSCTES 
               
               
                 5 
                 26 
                 11 
                 TAQLIAIAYYMLSIGATVPQVD 
               
               
                 330 
                 338 
                 332 
                 TTGVIVITS 
               
               
                 408 
                 415 
                 410 
                 YTTFCPLT 
               
               
                 119 
                 127 
                 121 
                 QPDVPCDNP 
               
               
                 129 
                 137 
                 131 
                 QPDVPCDNP 
               
               
                 343 
                 350 
                 346 
                 YTTYCPLT 
               
               
                 600 
                 609 
                 605 
                 ANYSSVAPIS 
               
               
                 259 
                 274 
                 263 
                 ESSVPVTSGSSILATT 
               
               
                 569 
                 582 
                 578 
                 AITIPESSAVVSTT 
               
               
                 587 
                 598 
                 592 
                 PTTLESVPLMQP 
               
               
                 542 
                 557 
                 546 
                 SPKSSVLASETSPIAP 
               
               
                 483 
                 497 
                 488 
                 SPAVPKSDVPATESA 
               
               
                 449 
                 468 
                 454 
                 SPAVPKSDVPATESAPVPEM 
               
               
                 622 
                 631 
                 630 
                 FGAAIIGIAA 
               
               
                 139 
                 147 
                 141 
                 QPDIPCDNP 
               
               
                 149 
                 157 
                 151 
                 QPDIPCDNP 
               
               
                 70 
                 117 
                 75 
                 EEPCDYPQQQPQEPCDYPQQPQEPCDYPQQPQEPCDYPQQ 
               
               
                   
                   
                   
                 PQEPCDNP 
               
               
                 58 
                 66 
                 63 
                 QEPCDYPQQ 
               
               
                 352 
                 358 
                 357 
                 TTPVSTA 
               
               
                 34 
                 55 
                 45 
                 ALIQKRSYDYYQEPCDDYPQQQ 
               
               
                 520 
                 529 
                 526 
                 ATEPSPVAPG 
               
               
                 232 
                 238 
                 234 
                 ESSVPAT 
               
               
                 472 
                 478 
                 476 
                 GSQPSIP 
               
               
                 512 
                 518 
                 516 
                 AAPKSSA 
               
               
                   
               
            
           
           
               
               
            
               
                 49. ALS10 
                   
               
               
                 MLQQYTLLLIYLSVATAKTITGVFNSFNSLTWSNAATYNYKGPGTPTWNAVLGWSLDGTSASPGDTFTLNMP 
               
               
                   
               
               
                 CVFKFTTSQTSVDLTAHGVKYATCQFQAGEEFMTFSTLTCTVSNTLTPSIKALGTVTLPLAFNVGGTGSSVD 
               
               
                   
               
               
                 LEDSKCFTAGTNTVTFNDGGKKISINVDFERSNVDPKGYLTDSRVIPSLNKVSTLFVAPQCANGYTSGTMGF 
               
               
                   
               
               
                 ANTYGDVQIDCSNIHVGITKGLNDWNYPVSSESFSYTKTCSSNGIFITYKNVPAGYRPFVDAYISATDVNSY 
               
               
                   
               
               
                 TLSYANEYTCAGGYWQRAPFTLRWTGYRNSDAGSNGIVIVATTRTVTDSTTAVTTLPFDPNRDKTKTIEILK 
               
               
                   
               
               
                 PIPTTTITTSYVGVTTSYSTKTAPIGETATVIVDIPYHTTTTVTSKWTGTITSTTTHTNPTDSIDTVIVQVP 
               
               
                   
               
               
                 SPNPTVTTTEYWSQSFATTTTITGPPGNTDTVLIREPPNHTVTTTEYWSESYTTTSTFTAPPGGTDSVIIKE 
               
               
                   
               
               
                 PPNPTVTTTEYWSESYTTTTTVTAPPGGTDTVIIREPPNHTVTTTEYWSQSYTTTTTVIAPPGGTDSVIIRE 
               
               
                   
               
               
                 PPNPTVTTTEYWSQSYATTTTITAPPGETDTVLIREPPNHTVTTTEYWSQSYATTTTITAPPGETDTVLIRE 
               
               
                   
               
               
                 PPNHTVTTTEYWSQSYTTTTTVIAPPGGTDSVIIREPPNPTVTTTEYWSQSYATTTTITAPPGETDTXLIRE 
               
               
                   
               
               
                 PPNHTVTTTEYWSQSYATTTTITAPPGETDTVLIREPPNHTVTTTEYWSQSFATTTTVTAPPGGTDTVIIRE 
               
               
                   
               
               
                 PPNHTVTTTEYWSQSXATTTTXTAPPGXTDTVLIREPPNPTVTTTEYWSQSYTTATTVTAPPGGTDTVIIYD 
               
               
                   
               
               
                 TMSSSEISSFSRPHYTNHTTLWSTTWVIETKTITETSCEGDKGCSWVSVSTRIVTIPNNIETPMVTNTVDTT 
               
               
                   
               
               
                 TTESTLQSPSGIFSESGVSVETESSTFTTAQTNPSVPTTESEVVFTTKGNNGNGPYESPSTNVKSSMDENSE 
               
               
                   
               
               
                 FTTSTAASTSTDIENETIATTGSVEASSPIISSSADETTTVTTTAESTSVIEQQTNNNGGGNAPSATSTSSP 
               
               
                   
               
               
                 STTTTANSDSVITSTTSTNQSQSQSNSDTQQTTLSQQMTSSLVSLHMLTTFDGSGSVIQHSTWLCGLITLLS 
               
               
                   
               
               
                 LFI 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 TGTITSTTTHTNPTDS 
                 408 
                 0.95 
               
               
                 1 
                 STTAVTTLPFDPNRDK 
                 337 
                 0.95 
               
               
                 2 
                 HGVKYATCQFQAGEEF 
                 89 
                 0.94 
               
               
                 2 
                 YWSESYTTTSTFTAPP 
                 479 
                 0.94 
               
               
                 2 
                 TLRWTGYRNSDAGSNG 
                 309 
                 0.94 
               
               
                 3 
                 TXLIREPPNHTVTTTE 
                 715 
                 0.93 
               
               
                 4 
                 ESEVVFTTKGNNGNGP 
                 976 
                 0.92 
               
               
                 4 
                 KTITETSCEGDKGCSW 
                 895 
                 0.92 
               
               
                 4 
                 SVDLEDSKCFTAGTNT 
                 142 
                 0.92 
               
               
                 5 
                 LGTVTLPLAFNVGGTG 
                 125 
                 0.91 
               
               
                 6 
                 YWSESYTTTTTVTAPP 
                 515 
                 0.90 
               
               
                 7 
                 TVLIREPPNHTVTTTE 
                 751 
                 0.89 
               
               
                 7 
                 TTTITAPPGETDTXLI 
                 703 
                 0.89 
               
               
                 7 
                 YWSQSYTTTTTVIAPP 
                 659 
                 0.89 
               
               
                 7 
                 TVLIREPPNHTVTTTE 
                 643 
                 0.89 
               
               
                 7 
                 TVLIREPPNHTVTTTE 
                 607 
                 0.89 
               
               
                 7 
                 YWSQSYTTTTTVIAPP 
                 551 
                 0.89 
               
               
                 7 
                 TVLIREPPNHTVTTTE 
                 463 
                 0.89 
               
               
                 7 
                 TTTITGPPGNTDTVLI 
                 451 
                 0.89 
               
               
                 7 
                 TSSPSTTTTANSDSVI 
                 1077 
                 0.89 
               
               
                 7 
                 MTFSTLTCTVSNTLTP 
                 105 
                 0.89 
               
               
                 8 
                 NGPYESPSTNVKSSMD 
                 989 
                 0.88 
               
               
                 8 
                 TVLIREPPNPTVTTTE 
                 823 
                 0.88 
               
               
                 8 
                 YWSQSXATTTTXTAPP 
                 803 
                 0.88 
               
               
                 8 
                 TVTSKWTGTITSTTTH 
                 402 
                 0.88 
               
               
                 8 
                 TKTCSSNGIFITYKNV 
                 253 
                 0.88 
               
               
                 8 
                 SGTMGFANTYGDVQID 
                 211 
                 0.88 
               
               
                 9 
                 SDSVITSTTSTNQSQS 
                 1088 
                 0.87 
               
               
                 9 
                 APSATSTSSPSTTTTA 
                 1071 
                 0.87 
               
               
                 9 
                 TSVIEQQTNNNGGGNA 
                 1056 
                 0.87 
               
               
                 10 
                 HTTLWSTTWVIETKTI 
                 882 
                 0.86 
               
               
                 10 
                 PPGXTDTVLIREPPNP 
                 817 
                 0.86 
               
               
                 10 
                 TVIIREPPNHTVTTTE 
                 787 
                 0.86 
               
               
                 10 
                 TTTITAPPGETDTVLI 
                 739 
                 0.86 
               
               
                 10 
                 SVIIREPPNPTVTTTE 
                 679 
                 0.86 
               
               
                 10 
                 TTTITAPPGETDTVLI 
                 631 
                 0.86 
               
               
                 10 
                 TTTITAPPGETDTVLI 
                 595 
                 0.86 
               
               
                 10 
                 SVIIREPPNPTVTTTE 
                 571 
                 0.86 
               
               
                 10 
                 TVIIREPPNHTVTTTE 
                 535 
                 0.86 
               
               
                 10 
                 TDSVIIKEPPNPTVTT 
                 497 
                 0.86 
               
               
                 10 
                 TSTNQSQSQSNSDTQQ 
                 1096 
                 0.86 
               
               
                 11 
                 SSEISSFSRPHYTNHT 
                 868 
                 0.85 
               
               
                 11 
                 TVIIYDTMSSSEISSF 
                 859 
                 0.85 
               
               
                 11 
                 SVDLTAHGVKYATCQF 
                 83 
                 0.85 
               
               
                 11 
                 TTTXTAPPGXTDTVLI 
                 811 
                 0.85 
               
               
                 11 
                 YWSQSYATTTTITAPP 
                 731 
                 0.85 
               
               
                 11 
                 YWSQSYATTTTITAPP 
                 695 
                 0.85 
               
               
                 11 
                 YWSQSYATTTTITAPP 
                 623 
                 0.85 
               
               
                 11 
                 YWSQSYATTTTITAPP 
                 587 
                 0.85 
               
               
                 11 
                 PIPTTTITTSYVGVTT 
                 361 
                 0.85 
               
               
                 12 
                 YWSQSYTTATTVTAPP 
                 839 
                 0.84 
               
               
                 12 
                 TDSIDTVIVQVPSPNP 
                 421 
                 0.84 
               
               
                 12 
                 TRTVTDSTTAVTTLPF 
                 331 
                 0.84 
               
               
                 12 
                 TWSNAATYNYKGPGTP 
                 31 
                 0.84 
               
               
                 12 
                 EYTCAGGYWQRAPFTL 
                 295 
                 0.84 
               
               
                 13 
                 SVETESSTFTTAQTNP 
                 955 
                 0.83 
               
               
                 13 
                 PNNIETPMVTNTVDTT 
                 921 
                 0.83 
               
               
                 13 
                 ASPGDTFTLNMPCVFK 
                 61 
                 0.83 
               
               
                 13 
                 GIFITYKNVPAGYRPF 
                 260 
                 0.83 
               
               
                 14 
                 TNTVDTTTTESTLQSP 
                 930 
                 0.82 
               
               
                 14 
                 TVIVDIPYHTTTTVTS 
                 390 
                 0.82 
               
               
                 14 
                 VGITKGLNDWNYPVSS 
                 232 
                 0.82 
               
               
                 14 
                 PKGYLTDSRVIPSLNK 
                 180 
                 0.82 
               
               
                 14 
                 SADETTTVTTTAESTS 
                 1042 
                 0.82 
               
               
                 14 
                 FTTSTAASTSTDIENE 
                 1009 
                 0.82 
               
               
                 15 
                 YWSQSFATTTTVTAPP 
                 767 
                 0.81 
               
               
                 15 
                 PTVTTTEYWSQSYATT 
                 688 
                 0.81 
               
               
                 15 
                 PTVTTTEYWSQSYATT 
                 580 
                 0.81 
               
               
                 15 
                 YSTKTAPIGETATVIV 
                 378 
                 0.81 
               
               
                 15 
                 TYNYKGPGTPTWNAVL 
                 37 
                 0.81 
               
               
                 15 
                 TIEILKPIPTTTITTS 
                 355 
                 0.81 
               
               
                 15 
                 SGSVIQHSTWLCGLIT 
                 1134 
                 0.81 
               
               
                 16 
                 TVTTTEYWSESYTTTT 
                 509 
                 0.80 
               
               
                 16 
                 DAYISATDVNSYTLSY 
                 277 
                 0.80 
               
               
                 16 
                 NVPAGYRPFVDAYISA 
                 267 
                 0.80 
               
               
                 16 
                 TCTVSNTLTPSIKALG 
                 111 
                 0.80 
               
               
                 17 
                 FQAGEEFMTFSTLTCT 
                 98 
                 0.79 
               
               
                 17 
                 SCEGDKGCSWVSVSTR 
                 901 
                 0.79 
               
               
                 17 
                 TVTAPPGGTDTVIIYD 
                 849 
                 0.79 
               
               
                 17 
                 TTTVTAPPGGTDTVII 
                 775 
                 0.79 
               
               
                 17 
                 HTVTTTEYWSQSYATT 
                 724 
                 0.79 
               
               
                 17 
                 HTVTTTEYWSQSYATT 
                 616 
                 0.79 
               
               
                 17 
                 TTTVTAPPGGTDTVII 
                 523 
                 0.79 
               
               
                 17 
                 TVTTTEYWSESYTTTS 
                 473 
                 0,79 
               
               
                 17 
                 PSLNKVSTLFVAPQCA 
                 191 
                 0.79 
               
               
                 17 
                 SPIISSSADETTTVTT 
                 1036 
                 0.79 
               
               
                 18 
                 PTVTTTEYWSQSYTTA 
                 832 
                 0.78 
               
               
                 18 
                 TTTVIAPPGGTDSVII 
                 667 
                 0.78 
               
               
                 18 
                 TTTVIAPPGGTDSVII 
                 559 
                 0.78 
               
               
                 18 
                 GIVIVATTRTVTDSTT 
                 324 
                 0.78 
               
               
                 18 
                 KKISINVDFERSNVDP 
                 165 
                 0.78 
               
               
                 18 
                 TNNNGGGNAPSATSTS 
                 1063 
                 0.78 
               
               
                 19 
                 HTVTTTEYWSQSXATT 
                 796 
                 0.77 
               
               
                 19 
                 TPSIKALGTVTLPLAF 
                 119 
                 0.77 
               
               
                 19 
                 TVTTTAESTSVIEQQT 
                 1048 
                 0.77 
               
               
                 19 
                 MDENSEFTTSTAASTS 
                 1003 
                 0.77 
               
               
                 20 
                 AQTNPSVPTTESEVVF 
                 966 
                 0.76 
               
               
                 20 
                 HTVTTTEYWSQSYTTT 
                 652 
                 0.76 
               
               
                 20 
                 HTVTTTEYWSQSYTTT 
                 544 
                 0.76 
               
               
                 20 
                 TPTWNAVLGWSLDGTS 
                 45 
                 0.76 
               
               
                 20 
                 TTTEYWSQSFATTTTI 
                 439 
                 0.76 
               
               
                 20 
                 PYHTTTTVTSKWTGTI 
                 396 
                 0.76 
               
               
                 20 
                 CANGYTSGTMGFANTY 
                 205 
                 0.76 
               
               
                 21 
                 TTWVIETKTITETSCE 
                 888 
                 0.75 
               
               
                 21 
                 HTVTTTEYWSQSFATT 
                 760 
                 0.75 
               
               
                 21 
                 TDVNSYTLSYANEYTC 
                 283 
                 0.75 
               
               
                 21 
                 LNDWNYPVSSESFSYT 
                 238 
                 0.75 
               
               
                 21 
                 YGDVQIDCSNIHVGIT 
                 220 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 4 
                 17 
                 11 
                 QYTLLLIYLSVATA 
               
               
                 424 
                 437 
                 430 
                 IDTVIVQVPSPNPT 
               
               
                 186 
                 208 
                 202 
                 DSRVIPSLNKVSTLFVAPQCANG 
               
               
                 388 
                 398 
                 394 
                 TATVIVDIPYH 
               
               
                 908 
                 921 
                 911 
                 CSWVSVSTRIVTIP 
               
               
                 1134 
                 1152 
                 1147 
                 SGSVIQHSTWLCGLITLLS 
               
               
                 1119 
                 1128 
                 1125 
                 TSSLVSLHML 
               
               
                 119 
                 135 
                 131 
                 TPSIKALGTVTLPLAFN 
               
               
                 323 
                 331 
                 328 
                 NGIVIVATT 
               
               
                 70 
                 77 
                 75 
                 NMPCVFKF 
               
               
                 81 
                 99 
                 94 
                 QTSVDLTAHGVKYATCQFQ 
               
               
                 109 
                 117 
                 111 
                 TLTCTVSNT 
               
               
                 262 
                 293 
                 277 
                 FITYKNVPAGYRPFVDAYISATDVNSYTLSYA 
               
               
                 49 
                 55 
                 53 
                 NAVLGWS 
               
               
                 222 
                 235 
                 230 
                 DVQIDCSNIHVGIT 
               
               
                 337 
                 346 
                 343 
                 STTAVTTLPF 
               
               
                 606 
                 612 
                 611 
                 DTVLIRE 
               
               
                 463 
                 468 
                 467 
                 TVLIRE 
               
               
                 750 
                 756 
                 755 
                 DTVLIRE 
               
               
                 642 
                 648 
                 647 
                 DTVLIRE 
               
               
                 369 
                 377 
                 371 
                 TSYVGVTTS 
               
               
                 498 
                 503 
                 503 
                 DSVIIK 
               
               
                 356 
                 362 
                 359 
                 IEILKPI 
               
               
                 559 
                 566 
                 563 
                 TTTVIAPP 
               
               
                 667 
                 674 
                 671 
                 TTTVIAPP 
               
               
                 570 
                 575 
                 575 
                 DSVIIR 
               
               
                 678 
                 683 
                 683 
                 DSVIIR 
               
               
                 1029 
                 1041 
                 1035 
                 TGSVEASSPIISS 
               
               
                 977 
                 982 
                 980 
                 SEVVFT 
               
               
                 859 
                 864 
                 860 
                 TVIIYD 
               
               
                 951 
                 958 
                 953 
                 ESGVSVET 
               
               
                 243 
                 250 
                 246 
                 YPVSSESF 
               
               
                 295 
                 301 
                 299 
                 EYTCAGG 
               
               
                 142 
                 153 
                 148 
                 SVDLEDSKCFTA 
               
               
                 1055 
                 1061 
                 1056 
                 STSVIEQ 
               
               
                 942 
                 949 
                 945 
                 LQSPSGIF 
               
               
                 1088 
                 1094 
                 1091 
                 SDSVITS 
               
               
                 870 
                 877 
                 876 
                 EISSFSRP 
               
               
                 888 
                 894 
                 894 
                 TTWVIET 
               
               
                 20 
                 27 
                 21 
                 ITGVFNSF 
               
               
                 969 
                 974 
                 969 
                 NPSVPT 
               
               
                   
               
            
           
           
               
               
            
               
                 50. IPF5185 
                   
               
               
                 MKVSTIFAAASALFAATTTLAQDVACLVDNQQVAVVDLDTGVCPFTIPASLAAFFTFVSLEEYNVQFYYTIV 
               
               
                   
               
               
                 NNVRYNTDIRNAGKVINVPARNLYGAGAVPFFQVHLEKQLEANSTAAIRRRLMGETPIVKRDQIDDFIASIE 
               
               
                   
               
               
                 NTEGTALEGSTLEVVDYVPGSSSASPSGSASPSGSESGSGSDSATIRSTTVVSSSSCESSGDSAATATGANG 
               
               
                   
               
               
                 ESTVTEQNTVVVTITSCHNDACHATTVPATASIGVTTVHGTETIFTTYCPLSSYETVESTKVITITSCSENK 
               
               
                   
               
               
                 CQETTVEATPSTATTVSEGVVTEYVTYCPVSSVETVASTKVITVVACDEHKCHETTAVATPTEVTTVVEGST 
               
               
                   
               
               
                 THYVTYKPTGSGPTQGETYATNAITSEGTVYVPKTTAVTTHGSTFETVAYITVTKATPTKGGEQHQPGSPAG 
               
               
                   
               
               
                 AATSAPGAPAPGASGAHASTANKVTVEAQATPGTLTPENTVAGGVNGEQVAVSAKTTISQTTVAKASGSGKA 
               
               
                   
               
               
                 AISTFEGAAAASAGASVLALALIPLAYFI* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 TVTKATPTKGGEQHQP 
                 412 
                 0.95 
               
               
                 2 
                 KPTGSGPTQGETYATN 
                 367 
                 0.93 
               
               
                 3 
                 KGGEQHQPGSPAGAAT 
                 420 
                 0.90 
               
               
                 4 
                 PLSSYETVESTKVITI 
                 266 
                 0.89 
               
               
                 4 
                 TETIFTTYCPLSSYET 
                 257 
                 0.89 
               
               
                 4 
                 TLEVVDYVPGSSSASP 
                 155 
                 0.89 
               
               
                 5 
                 VVTEYVTYCPVSSVET 
                 308 
                 0.88 
               
               
                 6 
                 HASTANKVTVEAQATP 
                 449 
                 0.86 
               
               
                 6 
                 APGAPAPGASGAHAST 
                 437 
                 0.86 
               
               
                 6 
                 ATPSTATTVSEGVVTE 
                 296 
                 0.86 
               
               
                 7 
                 TNAITSEGTVYVPKTT 
                 381 
                 0.85 
               
               
                 7 
                 TKVITITSCSENKCQE 
                 276 
                 0.85 
               
               
                 8 
                 NVQFYYTIVNNVRYNT 
                 64 
                 0.84 
               
               
                 8 
                 VEAQATPGTLTPENTV 
                 458 
                 0.84 
               
               
                 8 
                 TTVVEGSTTHYVTYKP 
                 353 
                 0.84 
               
               
                 8 
                 SATIRSTTVVSSSSCE 
                 187 
                 0.84 
               
               
                 9 
                 SSSCESSGDSAATATG 
                 198 
                 0.83 
               
               
                 9 
                 RLMGETPIVKRDQIDD 
                 123 
                 0.83 
               
               
                 10 
                 TAVTTHGSTFETVAYI 
                 396 
                 0.82 
               
               
                 10 
                 VITVVACDEHKCHETT 
                 329 
                 0.82 
               
               
                 10 
                 SCSENKCQETTVEATP 
                 283 
                 0.82 
               
               
                 10 
                 GSASPSGSESGSGSDS 
                 172 
                 0.82 
               
               
                 11 
                 VINVPARNLYGAGAVP 
                 87 
                 0.81 
               
               
                 11 
                 QVAVVDLDTGVCPFTI 
                 32 
                 0.81 
               
               
                 11 
                 ESTVTEQNTVVVTITS 
                 217 
                 0.81 
               
               
                 12 
                 DEHKCHETTAVATPTE 
                 336 
                 0.80 
               
               
                 13 
                 GGVNGEQVAVSAKTTI 
                 475 
                 0.79 
               
               
                 13 
                 VVVTITSCHNDACHAT 
                 226 
                 0.79 
               
               
                 14 
                 ETTAVATPTEVTTVVE 
                 342 
                 0.78 
               
               
                 15 
                 PGTLTPENTVAGGVNG 
                 464 
                 0.77 
               
               
                 15 
                 PGASGAHASTANKVTV 
                 443 
                 0.77 
               
               
                 16 
                 TTVAKASGSGKAAIST 
                 493 
                 0.76 
               
               
                 17 
                 PVSSVETVASTKVITV 
                 317 
                 0.75 
               
               
                 17 
                 FIASIENTEGTALEGS 
                 139 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 301 
                 350 
                 332 
                 ATTVSEGVVTEYVTYCPVSSVETVASTKVITVVACDEHKCH 
               
               
                   
                   
                   
                 ETTAVATPT 
               
               
                 514 
                 530 
                 524 
                 AASAGASVLALALIPLA 
               
               
                 21 
                 75 
                 25 
                 AQDVACLVDNQQVAVVDLDTGVCPFTIPASLAAFFTFVSLE 
               
               
                   
                   
                   
                 EYNVQFYYTIVNNV 
               
               
                 155 
                 174 
                 159 
                 TLEVVDYVPGSSSASPSGSA 
               
               
                 192 
                 204 
                 198 
                 STTVVSSSSCESS 
               
               
                 223 
                 254 
                 230 
                 QNTVVVTITSCHNDACHATTVPATASIGVTTV 
               
               
                 97 
                 111 
                 104 
                 GAGAVPFFQVHLEKQ 
               
               
                 262 
                 273 
                 267 
                 TTYCPLSSYETV 
               
               
                 405 
                 416 
                 410 
                 FETVAYITVTKA 
               
               
                 275 
                 284 
                 281 
                 STKVITITSC 
               
               
                 479 
                 487 
                 484 
                 GEQVAVSAK 
               
               
                 87 
                 95 
                 89 
                 VINVPARNL 
               
               
                 387 
                 401 
                 392 
                 EGTVYVPKTTAVTTH 
               
               
                 352 
                 359 
                 353 
                 VTTVVEGS 
               
               
                 361 
                 367 
                 365 
                 THYVTYK 
               
               
                 4 
                 19 
                 6 
                 STIFAAASALFAATTT 
               
               
                 455 
                 461 
                 459 
                 KVTVEAQ 
               
               
                 492 
                 498 
                 493 
                 QTTVAKA 
               
               
                 128 
                 134 
                 133 
                 TPIVKRD 
               
               
                 430 
                 450 
                 440 
                 PAGAATSAPGAPAPGASGAHA 
               
               
                 137 
                 142 
                 138 
                 DDFIAS 
               
               
                   
               
            
           
           
               
               
            
               
                 51. IPF15911 
                   
               
               
                 MSFWDNNKDSFKSAGKSTFKGITSGTKAVGQAGYRTYKKNEAKRKGVEYHDPIKNESKSGETNVPYNPSPLP 
               
               
                   
               
               
                 SKDKLSSYQPPPKRNVGTFGVPQRGEASHYSAPAPTSGQSTYPANQQQYQHPNEIQTSSGYQEPPPEYSVDS 
               
               
                   
               
               
                 NSDMQGFSAGSEYQRTAHPAPASTTFTPANQTSFIASPQPTSIATDNAIQNIQQQYNSVSKQPSPAPGLPPL 
               
               
                   
               
               
                 QHQPGNLVNPPLPPQVPQKSNVPPSLPSRTSVASVASSTSQQSVGQGSFVNAQEQPKPKPALPDPGSFAPPP 
               
               
                   
               
               
                 RRRDQQPIKPKILTNNSTMGNEKMSSPLVQGQSSSSNIGLHPSKSISEREHQSDYSDASSKPPSLPSRTSSS 
               
               
                   
               
               
                 HSNLPLKQKPPKPKKLQGDSSITTSHTPGYNSNYTHNVFSARSEEEYATPPKPPRPVEDEEYTNPPKPPRPV 
               
               
                   
               
               
                 EDEEYTNPPKPPRPVEDDEYTNPPKPPRPETQNSSVVTPRAIPDATELSNKKPPPPKPLKKPSTLDGSTSSP 
               
               
                   
               
               
                 PLYSELDNSFSKPKQIISESTNSQSAVSSELNSIFQKMNINKTESEAPASSPEVKPKPKPKPVPKPKPEMIT 
               
               
                   
               
               
                 KKQESPETSIRIATTTKPPPPVRRLSTPHKSPSPPPVPPARNYSRAPAPPPPKQSGPPNLDLELSSGWYAKT 
               
               
                   
               
               
                 NGPLQLPKVFHGINHKFSYTTSSGSYGKGTTTLTVRLKDLSIVTYKFEYSNNDISNVNVVIEKYVPSPIDTT 
               
               
                   
               
               
                 PSKQELIANHQRFGEYIASWCEHHRGKTVGRGECWDLAKEALQKGCGKHAFVSSYTIHGYPILQIGNVGNGV 
               
               
                   
               
               
                 YFINNSQQLDEVRRGDILQFNACTFYDASTGVTQSAGAPDHTSVVIGKSGDKLMVLEQNVGGKRYVVDGEIN 
               
               
                   
               
               
                 LKNLTKGEVYVYRAMPHEWAGEL* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 HKSPSPPPVPPARNYS 
                 605 
                 0.96 
               
               
                 1 
                 SGYQEPPPEYSVDSNS 
                 131 
                 0.96 
               
               
                 2 
                 TKKQESPETSIRIATT 
                 576 
                 0.95 
               
               
                 3 
                 DGSTSSPPLYSELDNS 
                 498 
                 0.93 
               
               
                 3 
                 DPGSFAPPPRRRDQQP 
                 280 
                 0.93 
               
               
                 4 
                 CEHHRGKTVGRGECWD 
                 741 
                 0.92 
               
               
                 4 
                 PPVPPARNYSRAPAPP 
                 611 
                 0.92 
               
               
                 5 
                 PRAIPDATELSNKKPP 
                 471 
                 0.91 
               
               
                 5 
                 PPKPPRPVEDDEYTNP 
                 440 
                 0.91 
               
               
                 5 
                 DSSITTSHTPGYNSNY 
                 379 
                 0.91 
               
               
                 6 
                 GEYIASWCEHHRGKTV 
                 734 
                 0.90 
               
               
                 6 
                 YSRAPAPPPPKQSGPP 
                 619 
                 0.90 
               
               
                 6 
                 LPLKQKPPKPKKLQGD 
                 364 
                 0.90 
               
               
                 6 
                 PKPKPALPDPGSFAPP 
                 272 
                 0.90 
               
               
                 7 
                 YGKGTTTLTVRLKDLS 
                 674 
                 0.89 
               
               
                 7 
                 YNSVSKQPSPAPGLPP 
                 200 
                 0.89 
               
               
                 8 
                 NVVIEKYVPSPIDTTP 
                 706 
                 0.88 
               
               
                 8 
                 FSYTTSSGSYGKGTTT 
                 665 
                 0.88 
               
               
                 8 
                 LSSGWYAKTNGPLQLP 
                 640 
                 0.88 
               
               
                 8 
                 PTSIATDNAIQNIQQQ 
                 184 
                 0.88 
               
               
                 9 
                 PPKPPRPVEDEEYTNP 
                 425 
                 0.87 
               
               
                 9 
                 PPKPPRPVEDEEYTNP 
                 410 
                 0.87 
               
               
                 9 
                 YKKNEAKRKGVEYHDP 
                 37 
                 0.87 
               
               
                 9 
                 PGLPPLQHQPGNLVNP 
                 211 
                 0.87 
               
               
                 10 
                 QELIANHQRFGEYIAS 
                 724 
                 0.86 
               
               
                 10 
                 IATTTKPPPPVRRLST 
                 588 
                 0.86 
               
               
                 11 
                 FYDASTGVTQSAGAPD 
                 817 
                 0.85 
               
               
                 11 
                 NKTESEAPASSPEVKP 
                 545 
                 0.85 
               
               
                 11 
                 EEEYATPPKPPRPVED 
                 404 
                 0.85 
               
               
                 11 
                 QTSFIASPQPTSIATD 
                 175 
                 0.85 
               
               
                 11 
                 AHPAPASTTFTPANQT 
                 161 
                 0.85 
               
               
                 12 
                 KQIISESTNSQSAVSS 
                 518 
                 0.84 
               
               
                 12 
                 GVEYHDPIKNESKSGE 
                 46 
                 0.84 
               
               
                 12 
                 PPKPPRPETQNSSVVT 
                 455 
                 0.84 
               
               
                 13 
                 PSPIDTTPSKQELIAN 
                 714 
                 0.83 
               
               
                 13 
                 PPKQSGPPNLDLELSS 
                 627 
                 0.83 
               
               
                 13 
                 SKSGETNVPYNPSPLP 
                 57 
                 0.83 
               
               
                 13 
                 TELSNKKPPPPKPLKK 
                 478 
                 0.83 
               
               
                 13 
                 HQPGNLVNPPLPPQVP 
                 218 
                 0.83 
               
               
                 13 
                 AGSEYQRTAHPAPAST 
                 153 
                 0.83 
               
               
                 14 
                 DKLSSYQPPPKRNVGT 
                 75 
                 0.82 
               
               
                 14 
                 KPVPKPKPEMITKKQE 
                 565 
                 0.82 
               
               
                 14 
                 DEEYTNPPKPPRPVED 
                 434 
                 0.82 
               
               
                 14 
                 DEEYTNPPKPPRPVED 
                 419 
                 0.82 
               
               
                 14 
                 SSTSQQSVGQGSFVNA 
                 253 
                 0.82 
               
               
                 14 
                 VNPPLPPQVPQKSNVP 
                 224 
                 0.82 
               
               
                 14 
                 PANQQQYQHPNEIQTS 
                 115 
                 0.82 
               
               
                 14 
                 PAPTSGQSTYPANQQQ 
                 105 
                 0.82 
               
               
                 15 
                 KEALQKGCGKHAFVSS 
                 759 
                 0.81 
               
               
                 15 
                 ASSPEVKPKPKPKPVP 
                 553 
                 0.81 
               
               
                 16 
                 EVRRGDILQFNACTFY 
                 803 
                 0.80 
               
               
                 16 
                 YNSNYTHNVFSARSEE 
                 390 
                 0.80 
               
               
                 17 
                 VGTFGVPQRGEASHYS 
                 88 
                 0.79 
               
               
                 17 
                 GECWDLAKEALQKGCG 
                 752 
                 0.79 
               
               
                 17 
                 LPKVFHGINHKFSYTT 
                 654 
                 0.79 
               
               
                 17 
                 RRRDQQPIKPKILTNN 
                 289 
                 0.79 
               
               
                 17 
                 TFKGITSGTKAVGQAG 
                 18 
                 0.79 
               
               
                 18 
                 PPPVRRLSTPHKSPSP 
                 595 
                 0.78 
               
               
                 18 
                 PKILTNNSTMGNEKMS 
                 298 
                 0.78 
               
               
                 18 
                 KAVGQAGYRTYKKNEA 
                 27 
                 0.78 
               
               
                 18 
                 TFTPANQTSFIASPQP 
                 169 
                 0.78 
               
               
                 19 
                 PSKSISEREHQSDYSD 
                 330 
                 0.77 
               
               
                 20 
                 IGNVGNGVYFINNSQQ 
                 785 
                 0.76 
               
               
                 20 
                 YSDASSKPPSLPSRTS 
                 343 
                 0.76 
               
               
                 21 
                 KDLSIVTYKFEYSNND 
                 686 
                 0.75 
               
               
                 21 
                 RTSSSHSNLPLKQKPP 
                 356 
                 0.75 
               
               
                 21 
                 SRTSVASVASSTSQQS 
                 244 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 704 
                 716 
                 710 
                 NVNVVIEKYVPSP 
               
               
                 651 
                 662 
                 655 
                 PLQLPKVFHGIN 
               
               
                 199 
                 255 
                 250 
                 QYNSVSKQPSPAPGLPPLQHQPGNLVNPPLPPQVPQKS 
               
               
                   
                   
                   
                 NVPPS 
               
               
                   
                   
                   
                 LPSRTSVASVASST 
               
               
                 871 
                 878 
                 875 
                 GEVYVYRA 
               
               
                 763 
                 786 
                 769 
                 QKGCGKHAFVSSYTIHGYPILQIG 
               
               
                 680 
                 695 
                 688 
                 TLTVRLKDLSIVTYKF 
               
               
                 466 
                 472 
                 471 
                 SSVVTPR 
               
               
                 833 
                 840 
                 836 
                 HTSVVIGK 
               
               
                 594 
                 617 
                 613 
                 PPPPVRRLSTPHKSPSPPPVPPAR 
               
               
                 809 
                 819 
                 812 
                 ILQFNACTFYD 
               
               
                 855 
                 862 
                 860 
                 KRYVVDGE 
               
               
                 503 
                 509 
                 507 
                 SPPLYSE 
               
               
                 257 
                 269 
                 263 
                 QQSVGQGSFVNAQ 
               
               
                 314 
                 320 
                 317 
                 SPLVQGQ 
               
               
                 134 
                 143 
                 139 
                 QEPPPEYSVD 
               
               
                 528 
                 538 
                 532 
                 QSAVSSELNSI 
               
               
                 46 
                 52 
                 50 
                 GVEYHDP 
               
               
                 65 
                 83 
                 80 
                 PYNPSPLPSKDKLSSYQPP 
               
               
                 734 
                 744 
                 738 
                 GEYIASWCEHH 
               
               
                 790 
                 795 
                 791 
                 NGVYFI 
               
               
                 295 
                 300 
                 298 
                 PIKPKI 
               
               
                 100 
                 108 
                 104 
                 SHYSAPAPT 
               
               
                 844 
                 851 
                 850 
                 KLMVLEQN 
               
               
                 325 
                 333 
                 331 
                 NIGLHPSKS 
               
               
                 361 
                 369 
                 367 
                 HSNLPLKQK 
               
               
                 486 
                 494 
                 488 
                 PPPKPLKKP 
               
               
                 563 
                 570 
                 565 
                 KPKPVPKP 
               
               
                 635 
                 643 
                 639 
                 NLDLELSSG 
               
               
                 176 
                 186 
                 181 
                 TSFIASPQPTS 
               
               
                 552 
                 561 
                 555 
                 PASSPEVKPK 
               
               
                 621 
                 631 
                 625 
                 RAPAPPPPKQS 
               
               
                 160 
                 167 
                 164 
                 TAHPAPAS 
               
               
                 395 
                 401 
                 397 
                 THNVFSA 
               
               
                 26 
                 32 
                 31 
                 TKAVGQA 
               
               
                 348 
                 356 
                 351 
                 SKPPSLPSR 
               
               
                 112 
                 122 
                 121 
                 STYPANQQQYQ 
               
               
                 274 
                 287 
                 275 
                 PKPALPDPGSFAPP 
               
               
                 821 
                 828 
                 827 
                 STGVTQSA 
               
               
                 723 
                 730 
                 724 
                 KQELIANH 
               
               
                 516 
                 522 
                 518 
                 KPKQIIS 
               
               
                   
               
            
           
           
               
               
            
               
                 52. PLB4 
                   
               
               
                 MNLLISLLLLSISLVLGSSPSGGYAPGIVQCPINSNSNSSSSSSRNTTFSFIREADSISDLEKQWIKQRQLK 
               
               
                   
               
               
                 VNKSLIEFLKSANLSNFNPQNFIDAKDYQGINLGLAFSGGSYRAMLNGAGQLMALDSRSSSSPSESGSGSGS 
               
               
                   
               
               
                 LGGILQSANYIGGLSGSSWLLGSLAMQGWPTVEEVVFENPHDVWNLTSSRQLVNQTGLWTIVFPVMFDNMNK 
               
               
                   
               
               
                 ALSHMNFWDNNADGIKFDLEAKEKAGFETSLTDAWARGLAHQLFPKGKDNYGSSETWSDIRNIDAFANHDMP 
               
               
                   
               
               
                 FPFVTGLGRKPGTTVYNLNSTVIEMNPFEFGSFDPSLNTFTDIKYLGTNVSNGVPVDSCVNGFDNSGFIVGS 
               
               
                   
               
               
                 SSSLFNSCLNTLVCDNCNSLNSVIKWILKKFLTYKLMKMWLFTNPNPFFNSQYAKSDNITTSDTLYVIDGGI 
               
               
                   
               
               
                 GGEVIPLSTLMVKERALDIVFAFDSDTNTKTNWPDGSALISSYERQFSQQGSSSICPYVPDTKTFLEKGLTA 
               
               
                   
               
               
                 KPTFFGCDAKNLTALEKDGVIPPLVVYFANRPYEYYSNVSTFDLTFTDEQKKGLIKNGFDVATRLNGTIDPE 
               
               
                   
               
               
                 FKSCIACAVIRREEERRGIEQSDQCKKCFKNYCWDGTYASGPAENYVNFTDSSLTNGSTVFYGKADAKVSSS 
               
               
                   
               
               
                 KGGLFGFLKRDTQNNDEKEEFIGVVRESNSDSLKLSKYLTIASLFALYLVIM* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 TGLGRKPGTTVYNLNS 
                 293 
                 0.94 
               
               
                 1 
                 GSSPSGGYAPGIVQCP 
                 17 
                 0.94 
               
               
                 2 
                 LGLAFSGGSYRAMLNG 
                 105 
                 0.92 
               
               
                 3 
                 LWTIVFPVMFDNMNKA 
                 202 
                 0.91 
               
               
                 4 
                 FIVGSSSSLFNSCLNT 
                 356 
                 0.90 
               
               
                 5 
                 NGSTVFYGKADAKVSS 
                 632 
                 0.89 
               
               
                 5 
                 NYCWDGTYASGPAENY 
                 607 
                 0.89 
               
               
                 5 
                 SDTNTKTNWPDGSALI 
                 457 
                 0.89 
               
               
                 5 
                 SETWSDIRNIDAFANH 
                 270 
                 0.89 
               
               
                 5 
                 PGIVQCPINSNSNSSS 
                 26 
                 0.89 
               
               
                 5 
                 SRSSSSPSESGSGSGS 
                 129 
                 0.89 
               
               
                 6 
                 YGKADAKVSSSKGGLF 
                 638 
                 0.87 
               
               
                 7 
                 TVIEMNPFEFGSFDPS 
                 309 
                 0.86 
               
               
                 7 
                 DNMNKALSHMNFWDNN 
                 212 
                 0.86 
               
               
                 8 
                 KGLTAKPTFFGCDAKN 
                 500 
                 0.85 
               
               
                 9 
                 EQSDQCKKCFKNYCWD 
                 596 
                 0.84 
               
               
                 9 
                 KGLIKNGFDVATRLNG 
                 556 
                 0.84 
               
               
                 9 
                 VYFANRPYEYYSNVST 
                 530 
                 0.84 
               
               
                 9 
                 AMQGWPTVEEVVFENP 
                 169 
                 0.84 
               
               
                 10 
                 KGGLFGFLKRDTQNND 
                 649 
                 0.83 
               
               
                 10 
                 YEYYSNVSTFDLTFTD 
                 537 
                 0.83 
               
               
                 10 
                 SFIREADSISDLEKQW 
                 50 
                 0.83 
               
               
                 10 
                 GEVIPLSTLMVKERAL 
                 434 
                 0.83 
               
               
                 10 
                 SSSRNTTFSFIREADS 
                 42 
                 0.83 
               
               
                 11 
                 CAVIRREEERRGIEQS 
                 583 
                 0.82 
               
               
                 11 
                 QFSQQGSSSICPYVPD 
                 478 
                 0.82 
               
               
                 11 
                 FTDIKYLGTNVSNGVP 
                 328 
                 0.82 
               
               
                 12 
                 QNFIDAKDYQGINLGL 
                 92 
                 0.81 
               
               
                 13 
                 GPAENYVNFTDSSLTN 
                 617 
                 0.80 
               
               
                 13 
                 ATRLNGTIDPEFKSCI 
                 566 
                 0.80 
               
               
                 13 
                 EEVVFENPHDVWNLTS 
                 177 
                 0.80 
               
               
                 14 
                 MWLFTNPNPFFNSQYA 
                 399 
                 0.79 
               
               
                 14 
                 NGVPVDSCVNGFDNSG 
                 340 
                 0.79 
               
               
                 15 
                 VPDTKTFLEKGLTAKP 
                 491 
                 0.78 
               
               
                 15 
                 IVFAFDSDTNTKTNWP 
                 451 
                 0.78 
               
               
                 15 
                 SCLNTLVCDNCNSLNS 
                 367 
                 0.78 
               
               
                 15 
                 WARGLAHQLFPKGKDN 
                 251 
                 0.78 
               
               
                 15 
                 PHDVWNLTSSRQLVNQ 
                 184 
                 0.78 
               
               
                 16 
                 EKEEFIGVVRESNSDS 
                 665 
                 0.77 
               
               
                 16 
                 MPFPFVTGLGRKPGTT 
                 287 
                 0.77 
               
               
                 16 
                 DLEAKEKAGFETSLTD 
                 234 
                 0.77 
               
               
                 17 
                 LKVNKSLIEFLKSANL 
                 71 
                 0.76 
               
               
                 17 
                 RESNSDSLKLSKYLTI 
                 674 
                 0.76 
               
               
                 17 
                 TSLTDAWARGLAHQLF 
                 245 
                 0.76 
               
               
                 17 
                 GSSWLLGSLAMQGWPT 
                 160 
                 0.76 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 521 
                 534 
                 527 
                 KDGVIPPLVVYFAN 
               
               
                 577 
                 587 
                 583 
                 FKSCIACAVIR 
               
               
                 339 
                 350 
                 345 
                 SNGVPVDSCVNG 
               
               
                 680 
                 697 
                 695 
                 SLKLSKYLTIASLFALYL 
               
               
                 4 
                 19 
                 6 
                 LISLLLLSISLVLGSS 
               
               
                 355 
                 377 
                 371 
                 GFIVGSSSSLFNSCLNTLVCDNC 
               
               
                 484 
                 495 
                 489 
                 SSSICPYVPDTK 
               
               
                 25 
                 34 
                 30 
                 APGIVQCPIN 
               
               
                 434 
                 447 
                 439 
                 GEVIPLSTLMVKER 
               
               
                 202 
                 210 
                 208 
                 LWTIVFPVM 
               
               
                 449 
                 455 
                 452 
                 LDIVFAF 
               
               
                 176 
                 184 
                 178 
                 VEEVVFENP 
               
               
                 253 
                 262 
                 258 
                 RGLAHQLFPK 
               
               
                 379 
                 395 
                 385 
                 SLNSVIKWILKKFLTYK 
               
               
                 422 
                 430 
                 425 
                 SDTLYVIDG 
               
               
                 598 
                 608 
                 603 
                 SDQCKKCFKNY 
               
               
                 468 
                 478 
                 472 
                 GSALISSYERQ 
               
               
                 288 
                 295 
                 292 
                 PFPFVTGL 
               
               
                 669 
                 675 
                 671 
                 FIGVVRE 
               
               
                 161 
                 168 
                 166 
                 SSWLLGSL 
               
               
                 68 
                 81 
                 78 
                 QRQLKVNKSLIEFL 
               
               
                 537 
                 548 
                 540 
                 YEYYSNVSTFDL 
               
               
                 102 
                 111 
                 106 
                 GINLGLAFSG 
               
               
                 193 
                 200 
                 199 
                 SRQLVNQT 
               
               
                 145 
                 153 
                 151 
                 LGGILQSAN 
               
               
                 635 
                 640 
                 638 
                 TVFYGK 
               
               
                 503 
                 514 
                 508 
                 TAKPTFFGCDAK 
               
               
                 330 
                 336 
                 336 
                 DIKYLGT 
               
               
                 642 
                 648 
                 646 
                 DAKVSSS 
               
               
                 301 
                 309 
                 309 
                 TTVYNLNST 
               
               
                   
               
            
           
           
               
               
            
               
                 53. PCT1 
                   
               
               
                 MARLTRKRTIEKELNGSSRVTRTLSMESISSLFKRNKKRKHNDGNDSSVNSSDNENINITDDEEQDHIDTKP 
               
               
                   
               
               
                 NHKKRKIKTKAEEEFEANEKKLDEELPIDLRKYRPRGFRFNLPPEDRPIRIYADGVFDLFHLGHMKQLEQAK 
               
               
                   
               
               
                 KSFPNVELVCGIPSDIETHKRKGLTVLTDEQRCETLMHCKWVDEVIPNAPWCVTPEFLQEHKIDYVAHDDLP 
               
               
                   
               
               
                 YASSDSDDIYKPIKEQGKFLTTQRTEGISTSDIITKIIRDYDKYLMRNFSRGATRKELNVSWLKMNELEFKK 
               
               
                   
               
               
                 HINDFRTYWMKNKTNINNVSRDLYFEIREFMRGKKFDFQKFIEDGNSQNSSNHGSDEESTNSSKVSSPLSDF 
               
               
                   
               
               
                 ASKYIGNRNKDLNRKGILNNFKGWINRDDHSEQETEEEIKPIVIKPIRRSRRLSGGSSTSSVPSTPVKRTAS 
               
               
                   
               
               
                 SASTTPKRKSPLKKSSSVKNTPKTK 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 QDHIDTKPNHKKRKIK 
                 65 
                 0.91 
               
               
                 1 
                 EFLQEHKIDYVAHDDL 
                 200 
                 0.91 
               
               
                 1 
                 DLRKYRPRGFRFNLPP 
                 101 
                 0.91 
               
               
                 2 
                 KRKIKTKAEEEFEANE 
                 76 
                 0.90 
               
               
                 2 
                 SWLKMNELEFKKHIND 
                 277 
                 0.90 
               
               
                 2 
                 TSDIITKIIRDYDKYL 
                 246 
                 0.90 
               
               
                 3 
                 PSTPVKRTASSASTTP 
                 423 
                 0.89 
               
               
                 3 
                 HCKWVDEVIPNAPWCV 
                 182 
                 0.89 
               
               
                 3 
                 TVLTDEQRCETLMHCK 
                 169 
                 0.89 
               
               
                 4 
                 SSTSSVPSTPVKRTAS 
                 417 
                 0.88 
               
               
                 5 
                 DHSEQETEEEIKPIVI 
                 389 
                 0.87 
               
               
                 6 
                 NINITDDEEQDHIDTK 
                 56 
                 0.86 
               
               
                 6 
                 SSDSDDIYKPIKEQGK 
                 219 
                 0.86 
               
               
                 7 
                 SSVNSSDNENINITDD 
                 47 
                 0.85 
               
               
                 7 
                 ASSASTTPKRKSPLKK 
                 431 
                 0.85 
               
               
                 7 
                 YFEIREFMRGKKFDFQ 
                 312 
                 0.85 
               
               
                 7 
                 PIRIYADGVFDLFKLG 
                 120 
                 0.85 
               
               
                 8 
                 KRTIEKELNGSSRVTR 
                 7 
                 0.83 
               
               
                 8 
                 DFASKYIGNRNKDLNR 
                 359 
                 0.83 
               
               
                 8 
                 PSDIETHKRKGLTVLT 
                 157 
                 0.83 
               
               
                 9 
                 NKKRKHNDGNDSSVNS 
                 36 
                 0.82 
               
               
                 9 
                 KKHINDFRTYWMKNKT 
                 287 
                 0.82 
               
               
                 9 
                 RTLSMESISSLFKRNK 
                 22 
                 0.82 
               
               
                 9 
                 DDLPYASSDSDDIYKP 
                 213 
                 0.82 
               
               
                 9 
                 RCETLMHCKWVDEVIP 
                 176 
                 0.82 
               
               
                 10 
                 IEDGNSQNSSNHGSDE 
                 330 
                 0.80 
               
               
                 10 
                 LMRNFSRGATRKELNV 
                 261 
                 0.80 
               
               
                 11 
                 RRLSGGSSTSSVPSTP 
                 411 
                 0.79 
               
               
                 12 
                 TEEEIKPIVIKPIRRS 
                 395 
                 0.78 
               
               
                 12 
                 FKGWINRDDHSEQETE 
                 381 
                 0.78 
               
               
                 12 
                 TQRTEGISTSDIITKI 
                 238 
                 0.78 
               
               
                 13 
                 TPKRKSPLKKSSSVKN 
                 437 
                 0.76 
               
               
                 13 
                 SSKVSSPLSDFASKYI 
                 350 
                 0.76 
               
               
                 13 
                 HGSDEESTNSSKVSSP 
                 341 
                 0.76 
               
               
                 13 
                 GSSRVTRTLSMESISS 
                 16 
                 0.76 
               
               
                 14 
                 KFDFQKFIEDGNSQNS 
                 323 
                 0.75 
               
               
                 14 
                 EVIPNAPWCVTPEFLQ 
                 188 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 147 
                 160 
                 153 
                 FPNVELVCGIPSDI 
               
               
                 121 
                 137 
                 131 
                 IRIYADGVFDLFHLGHM 
               
               
                 177 
                 220 
                 199 
                 CETLMHCKWVDEVIPNAPWCVTPEFLQEHKIDYVAHDDLPY 
               
               
                   
                   
                   
                 ASS 
               
               
                 400 
                 407 
                 404 
                 KPIVIKPI 
               
               
                 419 
                 430 
                 424 
                 TSSVPSTPVKRT 
               
               
                 350 
                 364 
                 354 
                 SSKVSSPLSDFASKY 
               
               
                 308 
                 315 
                 310 
                 SRDLYFEI 
               
               
                 441 
                 452 
                 447 
                 KSPLKKSSSVKN 
               
               
                 167 
                 174 
                 169 
                 GLTVLTDE 
               
               
                 273 
                 279 
                 277 
                 ELNVSWL 
               
               
                 99 
                 105 
                 101 
                 PIDLRKY 
               
               
                 250 
                 260 
                 252 
                 ITKIIRDYDKY 
               
               
                   
               
            
           
           
               
               
            
               
                 54. COX11 
                   
               
               
                 MNRLRIYTPIFRSTIVKPAVFRPYAFIVSRGIHTTGKLFQMQHQQQPSVPDQSSIEKQREWVDRLAREREER 
               
               
                   
               
               
                 QKYRNRTATYYTASLGIFFLALAFSAVPIYRAICQRTGWGGIPITDSTKFTPDKLIPVDTNKRIRIQFTCQS 
               
               
                   
               
               
                 SGILPWKFTPLQREVYVVPGETALAFYRAKNMSKEDIIGMATYSISPDNVAGYFNKIQCFCFEEQRLSAGEE 
               
               
                   
               
               
                 VDMPVFFFIDPDFAKDPAMRNIDDVVLHYSFFKAHYSDGELAAAPIGNMEMKASVVS 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 RSTIVKPAVFRPYAFI 
                 12 
                 0.96 
               
               
                 2 
                 GIPITDSTKFTPDKLI 
                 113 
                 0.94 
               
               
                 3 
                 DRLAREREERQKYRNR 
                 63 
                 0.93 
               
               
                 3 
                 IGMATYSISPDNVAGY 
                 182 
                 0.93 
               
               
                 4 
                 AGEEVDMPVFFFIDPD 
                 213 
                 0.89 
               
               
                 5 
                 RLRIYTPIFRSTIVKP 
                 3 
                 0.88 
               
               
                 6 
                 MQHQQQPSVPDQSSIE 
                 41 
                 0.87 
               
               
                 7 
                 QSSIEKQREWVDRLAR 
                 52 
                 0.84 
               
               
                 8 
                 LPWKFTPLQREVYVVP 
                 148 
                 0.83 
               
               
                 9 
                 KYRNRTATYYTASLGI 
                 74 
                 0.81 
               
               
                 9 
                 ISPDNVAGYFNKIQCF 
                 189 
                 0.81 
               
               
                 10 
                 GETALAFYRAKNMSKE 
                 164 
                 0.78 
               
               
                 11 
                 GELAAAPIGNMEMKAS 
                 255 
                 0.76 
               
               
                 11 
                 RIRIQFTCQSSGILPW 
                 135 
                 0.76 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 239 
                 252 
                 244 
                 DDVVLHYSFFKAHY 
               
               
                 200 
                 208 
                 203 
                 KIQCFCFEE 
               
               
                 137 
                 17 
                 1161 
                 RIQFTCQSSGILPWKFTPLQREVYVVPGETALAFY 
               
               
                 6 
                 31 
                 18 
                 IYTPIFRSTIVKPAVFRPYAFIVSRG 
               
               
                 82 
                 108 
                 92 
                 YYTASLGIFFLALAFSAVPIYRAICQR 
               
               
                 218 
                 228 
                 223 
                 DMPVFFFDPD 
               
               
                 124 
                 131 
                 127 
                 PDKLIPVD 
               
               
                 39 
                 52 
                 46 
                 FQMQHQQQPSVPDQ 
               
               
                 187 
                 198 
                 188 
                 YSISPDNVAGYF 
               
               
                   
               
            
           
           
               
               
            
               
                 55. KEL1 
                   
               
               
                 MALFKLGGKLKKKDHQSDPDTTVSSSSSTNSANRKSTSRFSSILHSSAAPMPSISNQPAHTSRPPPHANLSV 
               
               
                   
               
               
                 TTPWNRFKLFDSPFPRYRHAAASIASEKNELFLMGGLKDGSVFGDTWKIVPQINHEGDIINYVAENIEVVNN 
               
               
                   
               
               
                 NNPPARVGHAAVLCGNAFIVYGGDTVDTDTNGFPDNNFYLFNINNHKYTIPNHILNKPNGRYGHTIGVISLN 
               
               
                   
               
               
                 NTSSRLYLFGGQLENDVFNDLYYFELNSFKSPKATWQLVEPLNDVKPPPLTNHSMSVYKNKVYVFGGVYNNE 
               
               
                   
               
               
                 KVSNDLWVFDAINDTWTQVTTTGDIPPPVNEHSSCVADDRMYVYGGNDFQGIIYSSLYVLDLQTLEWSSLQS 
               
               
                   
               
               
                 SAEKSGPGPRCGHSMTLLPKFNKILIMGGDKNDYVDSDPHNFETYESFNGEEVGTMVYELDLNIIDHFLAAS 
               
               
                   
               
               
                 APVNAPTIIPPVASYEELPKPKKPAASARNDLQGYDRHARSFSGGPEDFATPQASARGSPSPERTQGGGDNF 
               
               
                   
               
               
                 VEVDLPSTTISQVDDDPPYDTTSLNQPQEVTNGHVDDEPFRRRSLDPKFDDHSGAPEVAPVAVPVTEPVSAP 
               
               
                   
               
               
                 VTAPVAEPVVAPAVAPDASGKVKKIISELTNELVQLKATTKEQMQKATEKIEQLERQNSLLHQSQQRDAESY 
               
               
                   
               
               
                 TKQIEEKDVLINELKSSLDPSAWDPEQPQTATNISELNRYKLERLELNNKLLYLEQENVKLKDQFAEFEPFM 
               
               
                   
               
               
                 DHQIGELDKFQKVIKVQEEQIDKLSNQVKDQEALHKQIYDWKSKFESLSLEFENYRAIHNDDDISDGEVELQ 
               
               
                   
               
               
                 DDDRSILSSAKSRKDISSQLGNLVSLWNQKHASSSSRDLSAPPVINPESHPVVAKLQSQVDELLKIGKQNET 
               
               
                   
               
               
                 TFSQEIEALRKELQEKTTSLKTVEENYRESIQSVNNTSKALKLNQEELSNQRILMERLIKENNELKLYKKAS 
               
               
                   
               
               
                 SKKLGSRDGTPVVNEYQQGEDSPGVDELNNDDDDDEDVISTAHYNMKIKDLEADLYILKQERDQLKDNVTSL 
               
               
                   
               
               
                 QKQLYLAQNQ 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 YQQGEDSPGVDELNND 
                 952 
                 0.94 
               
               
                 1 
                 AHTSRPPPHANLSVTT 
                 59 
                 0.94 
               
               
                 2 
                 NGHVDDEPFRRRSLDP 
                 536 
                 0.93 
               
               
                 2 
                 KILIMGGDKNDYVDSD 
                 383 
                 0.93 
               
               
                 3 
                 TGDIPPPVNEHSSCVA 
                 310 
                 0.90 
               
               
                 4 
                 LKSSLDPSAWDPEQPQ 
                 662 
                 0.89 
               
               
                 4 
                 MPSISNQPAHTSRPPP 
                 51 
                 0.89 
               
               
                 5 
                 SQEIEALRKELQEKTT 
                 867 
                 0.88 
               
               
                 5 
                 PSTTISQVDDDPPYDT 
                 510 
                 0.88 
               
               
                 5 
                 IVYGGDTVDTDTNGFP 
                 163 
                 0.88 
               
               
                 6 
                 DGEVELQDDDRSILSS 
                 786 
                 0.86 
               
               
                 6 
                 TPQASARGSPSPERTQ 
                 483 
                 0.86 
               
               
                 6 
                 APTIIPPVASYEELPK 
                 437 
                 0.86 
               
               
                 6 
                 NGEEVGTMVYELDLNI 
                 409 
                 0.86 
               
               
                 6 
                 FQGIIYSSLYVLDLQT 
                 337 
                 0.86 
               
               
                 6 
                 HSSCVADDRMYVYGGN 
                 320 
                 0.86 
               
               
                 6 
                 LKKKDHQSDPDTTVSS 
                 10 
                 0.86 
               
               
                 7 
                 RRRSLDPKFDDHSGAP 
                 545 
                 0.85 
               
               
                 7 
                 GPEDFATPQASARGSP 
                 477 
                 0.85 
               
               
                 7 
                 AEKSGPGPRCGHSMTL 
                 362 
                 0.85 
               
               
                 7 
                 PNHILNKPNGRYGHTI 
                 195 
                 0.85 
               
               
                 8 
                 EDVISTAHYNMKIKDL 
                 972 
                 0.84 
               
               
                 8 
                 LGSRDGTPVVNEYQQG 
                 940 
                 0.84 
               
               
                 8 
                 QEEQIDKLSNQVKDQE 
                 737 
                 0.84 
               
               
                 8 
                 MQKATEKIEQLERQNS 
                 620 
                 0.84 
               
               
                 8 
                 RHARSFSGGPEDFATP 
                 469 
                 0.84 
               
               
                 8 
                 TVSSSSSTNSANRKST 
                 22 
                 0.84 
               
               
                 8 
                 TVDTDTNGFPDNNFYL 
                 169 
                 0.84 
               
               
                 9 
                 SRDLSAPPVINPESHP 
                 828 
                 0.83 
               
               
                 9 
                 ANLSVTTPWNRFKLFD 
                 68 
                 0.83 
               
               
                 9 
                 LNIIDHFLAASAPVNA 
                 422 
                 0.83 
               
               
                 9 
                 TLEWSSLQSSAEKSGP 
                 352 
                 0.83 
               
               
                 10 
                 ESLSLEFENYRAIHND 
                 766 
                 0.82 
               
               
                 10 
                 TKQIEEKDVLINELKS 
                 649 
                 0.82 
               
               
                 10 
                 AVAPDASGKVKKIISE 
                 589 
                 0.82 
               
               
                 10 
                 EGDIINYVAENIEVVN 
                 128 
                 0.82 
               
               
                 11 
                 KTVEENYRESIQSVNN 
                 885 
                 0.81 
               
               
                 11 
                 RKELQEKTTSLKTVEE 
                 874 
                 0.81 
               
               
                 11 
                 DPEQPQTATNISELNR 
                 672 
                 0.81 
               
               
                 11 
                 ERTQGGGDNFVEVDLP 
                 495 
                 0.81 
               
               
                 11 
                 RGSPSPERTQGGGDNF 
                 489 
                 0.81 
               
               
                 11 
                 GVYNNEKVSNDLWVFD 
                 283 
                 0.81 
               
               
                 11 
                 NGRYGHTIGVISLNNT 
                 203 
                 0.81 
               
               
                 12 
                 QVDDDPPYDTTSLNQP 
                 516 
                 0.80 
               
               
                 12 
                 GHSMTLLPKFNKILIM 
                 372 
                 0.80 
               
               
                 13 
                 ADLYILKQERDQLKDN 
                 989 
                 0.79 
               
               
                 13 
                 DQEALHKQIYDWKSKF 
                 750 
                 0.79 
               
               
                 13 
                 SELNRYKLERLELNNK 
                 683 
                 0.79 
               
               
                 13 
                 FVEVDLPSTTISQVDD 
                 504 
                 0.79 
               
               
                 13 
                 RMYVYGGNDFQGIIYS 
                 328 
                 0.79 
               
               
                 14 
                 LFDSPFPRYRHAAASI 
                 81 
                 0.78 
               
               
                 14 
                 PKATWQLVEPLNDVKP 
                 248 
                 0.78 
               
               
                 15 
                 TAPVAEPVVAPAVAPD 
                 578 
                 0.77 
               
               
                 15 
                 TTSLNQPQEVTNGHVD 
                 525 
                 0.77 
               
               
                 16 
                 KQIYDWKSKFESLSLE 
                 756 
                 0.76 
               
               
                 16 
                 HQSQQRDAESYTKQIE 
                 638 
                 0.76 
               
               
                 16 
                 PVAVPVTEPVSAPVTA 
                 564 
                 0.76 
               
               
                 16 
                 PLTNHSMSVYKNKVYV 
                 265 
                 0.76 
               
               
                 17 
                 VASYEELPKPKKPAAS 
                 444 
                 0.75 
               
               
                 17 
                 SANRKSTSRFSSILHS 
                 31 
                 0.75 
               
               
                 17 
                 KVYVFGGVYNNEKVSN 
                 277 
                 0.75 
               
               
                 17 
                 DGSVFGDTWKIVPQIN 
                 111 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 559 
                 593 
                 566 
                 APEVAPVAVPVTEPVSAPVTAPVAEPVVAPAVAPD 
               
               
                 339 
                 353 
                 345 
                 GIIYSSLYVLDLQTL 
               
               
                 828 
                 858 
                 845 
                 SRDLSAPPVINPESHPVVAKLQSQVDELLKI 
               
               
                 148 
                 167 
                 155 
                 PARVGHAAVLCGNAFIVYGG 
               
               
                 270 
                 283 
                 281 
                 SMSVYKNKVYVFGG 
               
               
                 414 
                 450 
                 432 
                 GTMVYELDLNIIDHFLAASAPVNAPTIIPPVASYEEL 
               
               
                 504 
                 520 
                 507 
                 FVEVDLPSTTISQVDDD 
               
               
                 730 
                 739 
                 733 
                 FQKVIKVQEE 
               
               
                 1002 
                 1015 
                 1011 
                 KDNVTSLQKQLYLA 
               
               
                 314 
                 334 
                 323 
                 PPPVNEHSSCVADDRMYVYGG 
               
               
                 607 
                 614 
                 612 
                 NELVQLKA 
               
               
                 809 
                 819 
                 815 
                 SSQLGNLVSLW 
               
               
                 209 
                 215 
                 212 
                 TIGVISL 
               
               
                 696 
                 707 
                 701 
                 NNKLLYLEQENV 
               
               
                 251 
                 267 
                 255 
                 TWQLVEPLNDVKPPPLT 
               
               
                 291 
                 299 
                 297 
                 SNDLWVFDA 
               
               
                 234 
                 243 
                 236 
                 FNDLYYFELN 
               
               
                 750 
                 758 
                 756 
                 DQEALHKQI 
               
               
                 988 
                 995 
                 992 
                 EADLYILK 
               
               
                 633 
                 640 
                 639 
                 QNSLLHQS 
               
               
                 40 
                 52 
                 46 
                 FSSILHSSAAPMP 
               
               
                 60 
                 73 
                 69 
                 HTSRPPPHANLSVT 
               
               
                 221 
                 227 
                 222 
                 RLYLFGG 
               
               
                 119 
                 125 
                 124 
                 WKIVPQI 
               
               
                 946 
                 952 
                 950 
                 TPVVNEY 
               
               
                 654 
                 661 
                 660 
                 EKDVLINE 
               
               
                 132 
                 142 
                 133 
                 INYVAENIEVV 
               
               
                 81 
                 97 
                 94 
                 LFDSPFPRYRHAAASIA 
               
               
                 930 
                 935 
                 932 
                 KLYKKA 
               
               
                 595 
                 604 
                 600 
                 SGKVKKIISE 
               
               
                 797 
                 802 
                 800 
                 SILSSA 
               
               
                 368 
                 384 
                 376 
                 GPRCGHSMTLLPKFNKI 
               
               
                 192 
                 200 
                 196 
                 YTIPNHILN 
               
               
                 765 
                 771 
                 767 
                 FESLSLE 
               
               
                 663 
                 669 
                 665 
                 KSSLDPS 
               
               
                 355 
                 361 
                 359 
                 WSSLQSS 
               
               
                 20 
                 26 
                 25 
                 DTTVSSS 
               
               
                 4 
                 9 
                 5 
                 FKLGGK 
               
               
                 742 
                 747 
                 746 
                 DKLSNQ 
               
               
                 452 
                 458 
                 453 
                 KPKKPAA 
               
               
                   
               
            
           
           
               
               
            
               
                 56. GAP1 
                   
               
               
                 MAIKIGINGFGRIGRLVLRVALGRKDIEVVAVNDPFIAPDYAAYMFKYDSTHGRYKGEVTASGDDLVIDGHK 
               
               
                   
               
               
                 IKVFQERDPANIPWGKSGVDYVIESTGVFTKLEGAQKHIDAGAKKVIITAPSADAPMFVVGVNEDKYTPDLK 
               
               
                   
               
               
                 IISNASCTTNCLAPLAKVVNDTFGIEEGLMTTVHSITATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAV 
               
               
                   
               
               
                 GKVIPELNGKLTGMSLRVPTTDVSVVDLTVRLKKAASYEEIAQAIKKASEGPLKGVLGYTEDAVVSTDFLGS 
               
               
                   
               
               
                 SYSSIFDEKAGILLSPTFVKLISWYDNEYGYSTRVVDLLEHVAKASA 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 TAPSADAPMFVVGVNE 
                 121 
                 0.94 
               
               
                 2 
                 VGVNEDKYTPDLKIIS 
                 132 
                 0.93 
               
               
                 3 
                 KKASEGPLKGVLGYTE 
                 262 
                 0.91 
               
               
                 4 
                 PSHKDWRGGRTASGNI 
                 190 
                 0.89 
               
               
                 4 
                 QKTVDGPSHKDWRGGR 
                 184 
                 0.89 
               
               
                 5 
                 DYVIESTGVFTKLEGA 
                 92 
                 0.85 
               
               
                 5 
                 PLKGVLGYTEDAVVST 
                 268 
                 0.85 
               
               
                 5 
                 KYTPDLKIISNASCTT 
                 138 
                 0.85 
               
               
                 5 
                 TKLEGAQKHIDAGAKK 
                 102 
                 0.85 
               
               
                 6 
                 TGMSLRVPTTDVSVVD 
                 228 
                 0.84 
               
               
                 6 
                 QKHIDAGAKKVIITAP 
                 108 
                 0.84 
               
               
                 7 
                 IPELNGKLTGMSLRVP 
                 220 
                 0.83 
               
               
                 7 
                 IEEGLMTTVHSITATQ 
                 169 
                 0.83 
               
               
                 8 
                 YAAYMFKYDSTHGRYK 
                 41 
                 0.82 
               
               
                 9 
                 GHKIKVFQERDPANIP 
                 70 
                 0.81 
               
               
                 10 
                 LISWYDNEYGYSTRVV 
                 309 
                 0.80 
               
               
                 11 
                 KAGILLSPTFVKLISW 
                 297 
                 0.79 
               
               
                 11 
                 YSSIFDEKAGILLSPT 
                 290 
                 0.79 
               
               
                 12 
                 PFIAPDYAAYMFKYDS 
                 35 
                 0.78 
               
               
                 13 
                 STHGRYKGEVTASGDD 
                 50 
                 0.77 
               
               
                 14 
                 IPWGKSGVDYVIESTG 
                 84 
                 0.75 
               
               
                 14 
                 ASCTTNCLAPLAKVVN 
                 149 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 14 
                 24 
                 19 
                 GRLVLRVALGR 
               
               
                 231 
                 252 
                 242 
                 SLRVPTTDVSVVDLTVRLKKAA 
               
               
                 152 
                 166 
                 160 
                 TTNCLAPLAKVVNDT 
               
               
                 320 
                 332 
                 327 
                 STRVVDLLEHVAK 
               
               
                 27 
                 47 
                 29 
                 IEVVAVNDPFIAPDYAAYMFK 
               
               
                 128 
                 135 
                 131 
                 PMFVVGVN 
               
               
                 299 
                 312 
                 304 
                 GILLSPTFVKLISW 
               
               
                 277 
                 293 
                 283 
                 EDAVVSTDFLGSSYSSI 
               
               
                 213 
                 222 
                 218 
                 AKAVGKVIPE 
               
               
                 90 
                 103 
                 92 
                 GVDYVIESTGVFTK 
               
               
                 115 
                 125 
                 121 
                 AKKVIITAPSA 
               
               
                 269 
                 275 
                 272 
                 LKGVLGY 
               
               
                 64 
                 78 
                 74 
                 DDLVIDGHKIKVFQE 
               
               
                 140 
                 150 
                 148 
                 TPDLKIISNAS 
               
               
                 174 
                 181 
                 179 
                 MTTVHSIT 
               
               
                 254 
                 263 
                 260 
                 YEEIAQAIKK 
               
               
                 204 
                 209 
                 208 
                 NIIPSS 
               
               
                   
               
            
           
           
               
               
            
               
                 57. IRS4_CANAL 
                   
               
               
                 MSGNSAANAAALAAFNGIGKKKKESTTKLNGTDNNTNHLGVIGSTSNQTKQHQQQQQQPQALRTPLPAHPSR 
               
               
                   
               
               
                 KKSNKFSQLKRLNTAPAMASLQPALQIASPSISPTQPSAPASALDSDPDYFTLSPHTIPSKNEIAKSPQTPQ 
               
               
                   
               
               
                 DMIRNVRQSIELKAIPNNAQAKRLSVDYSPQEMLKNLRHSLHSRTKTSPMLTTSDKMGQTMLAEMRDRLENT 
               
               
                   
               
               
                 RRIASNSVASLSLSPNLDFNKSTSDVSNLSHHYDVDTVSTDSFASFSSSINDRHLPHGISIDVTNHDSDEDE 
               
               
                   
               
               
                 IDDREREEDHEPLDNGELKSTNNKVTVSSRLRRKPPPGEDFQMQLNDKSRDTISSGSYSLNPDEVYSFTDPD 
               
               
                   
               
               
                 SYENLVSEVEVGETTRLFPQFPDANHYHQHSSKFRKKHQKVKPINGIYYRDMDSSNTSDTEESTSNLPSRST 
               
               
                   
               
               
                 TPLLGQPQQQVHFRSTMRKANTKKDKKSRFNELKPWKNHNDLNYLTDQEKKRYEGIWASNKGNYMSQVVIKL 
               
               
                   
               
               
                 HGVNYETQKDPKEEAKMEHSRTAALLSAAAVEDSNYNGNNSLHNLDSVEINQLICGPVVKRIWKRSRLPSDT 
               
               
                   
               
               
                 LEKIWNLIDFRRDGTLNKNEFLVGMWLVDQCLYGRKLPKKVDNVVWDSLGGIGVNVTVKKKK* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 PINGIYYRDMDSSNTS 
                 403 
                 0.94 
               
               
                 2 
                 DKSRDTISSGSYSLNP 
                 335 
                 0.93 
               
               
                 3 
                 PDEVYSFTDPDSYENL 
                 350 
                 0.90 
               
               
                 4 
                 ASPSISPTQPSAPASA 
                 100 
                 0.89 
               
               
                 5 
                 AVEDSNYNGNNSLHNL 
                 534 
                 0.88 
               
               
                 5 
                 AKSPQTPQDMIRNVRQ 
                 137 
                 0.88 
               
               
                 6 
                 LEKIWNLIDFRRDGTL 
                 577 
                 0.87 
               
               
                 6 
                 KQHQQQQQQPQALRTP 
                 50 
                 0.87 
               
               
                 7 
                 TKTSPMLTTSDKMGQT 
                 189 
                 0.86 
               
               
                 7 
                 NGIGKKKKESTTKLNG 
                 16 
                 0.86 
               
               
                 8 
                 DTEESTSNLPSRSTTP 
                 419 
                 0.85 
               
               
                 8 
                 YRDMDSSNTSDTEEST 
                 409 
                 0.85 
               
               
                 8 
                 PHTIPSKNEIAKSPQT 
                 127 
                 0.85 
               
               
                 9 
                 YETQKDPKEEAKMEHS 
                 509 
                 0.84 
               
               
                 9 
                 HGISIDVTNHDSDEDE 
                 273 
                 0.84 
               
               
                 10 
                 NHYHQHSSKFRKKHQK 
                 385 
                 0.83 
               
               
                 10 
                 NSVASLSLSPNLDFNK 
                 222 
                 0.83 
               
               
                 10 
                 TTSDKMGQTMLAEMRD 
                 196 
                 0.83 
               
               
                 11 
                 KKRYEGIWASNKGNYM 
                 482 
                 0.82 
               
               
                 11 
                 ANTKKDKKSRFNELKP 
                 452 
                 0.82 
               
               
                 12 
                 PGEDFQMQLNDKSRDT 
                 325 
                 0.81 
               
               
                 12 
                 REREEDHEPLDNGELK 
                 292 
                 0.81 
               
               
                 13 
                 QQQVHFRSTMRKANTK 
                 440 
                 0.80 
               
               
                 13 
                 KVTVSSRLRRKPPPGE 
                 312 
                 0.80 
               
               
                 13 
                 DEDEIDDREREEDHEP 
                 285 
                 0.80 
               
               
                 14 
                 GSYSLNPDEVYSFTDP 
                 344 
                 0.79 
               
               
                 14 
                 SSSINDRHLPHGISID 
                 263 
                 0.79 
               
               
                 14 
                 PSAPASALDSDPDYFT 
                 109 
                 0.79 
               
               
                 15 
                 LRTPLPAHPSRKKSNK 
                 62 
                 0.78 
               
               
                 15 
                 LPSRSTTPLLGQPQQQ 
                 427 
                 0.78 
               
               
                 15 
                 SEVEVGETTRLFPQFP 
                 367 
                 0.78 
               
               
                 15 
                 KKESTTKLNGTDNNTN 
                 22 
                 0.78 
               
               
                 16 
                 CGPVVKRIWKRSRLPS 
                 559 
                 0.77 
               
               
                 16 
                 AALLSAAAVEDSNYNG 
                 527 
                 0.77 
               
               
                 16 
                 LGVIGSTSNQTKQHQQ 
                 39 
                 0.77 
               
               
                 17 
                 MWLVDQCLYGRKLPKK 
                 601 
                 0.76 
               
               
                 17 
                 KKSRFNELKPWKNHND 
                 458 
                 0.76 
               
               
                 18 
                 NVVWDSLGGIGVNVTV 
                 619 
                 0.75 
               
               
                 18 
                 KSTSDVSNLSHHYDVD 
                 237 
                 0.75 
               
               
                 18 
                 RQSIELKAIPNNAQAK 
                 151 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 547 
                 566 
                 560 
                 HNLDSVEINQLICGPVVKRI 
               
               
                 596 
                 612 
                 606 
                 EFLVGMWLVDQCLYGRK 
               
               
                 497 
                 508 
                 502 
                 MSQVVIKLHGVN 
               
               
                 363 
                 372 
                 368 
                 ENLVSEVEVG 
               
               
                 526 
                 537 
                 532 
                 TAALLSAAAVED 
               
               
                 221 
                 232 
                 226 
                 SNSVASLSLSPN 
               
               
                 242 
                 254 
                 248 
                 VSNLSHHYDVDTV 
               
               
                 627 
                 635 
                 631 
                 GIGVNVTVK 
               
               
                 312 
                 318 
                 316 
                 KVTVSSR 
               
               
                 89 
                 117 
                 96 
                 AMASLQPALQIASPSISPTQPSAPASALD 
               
               
                 166 
                 173 
                 171 
                 KRLSVDYS 
               
               
                 432 
                 446 
                 442 
                 TTPLLGQPQQQVHFR 
               
               
                 8 
                 15 
                 12 
                 NAAALAAF 
               
               
                 614 
                 624 
                 623 
                 PKKVDNVVWDS 
               
               
                 38 
                 44 
                 41 
                 HLGVIGS 
               
               
                 51 
                 70 
                 68 
                 QHQQQQQQPQALRTPLPAHP 
               
               
                 268 
                 280 
                 274 
                 DRHLPHGISIDVT 
               
               
                 180 
                 187 
                 184 
                 NLRHSLHS 
               
               
                 122 
                 130 
                 125 
                 YFTLSPHTI 
               
               
                 398 
                 407 
                 401 
                 HQKVKPINGI 
               
               
                 150 
                 159 
                 153 
                 VRQSIELKAI 
               
               
                 384 
                 392 
                 389 
                 ANHYHQHSS 
               
               
                 350 
                 356 
                 356 
                 PDEVYSF 
               
               
                 78 
                 84 
                 81 
                 FSQLKRL 
               
               
                 259 
                 264 
                 263 
                 FASFSS 
               
               
                 343 
                 348 
                 345 
                 SGSYSL 
               
               
                   
               
            
           
           
               
               
            
               
                 58. INP51 
                   
               
               
                 MRLYLIEKPRTFVITTNTHALIIRHPSPTYKHSGIKGLVSGHSKDKDQNKDTKVLVEFVLKEYLDLSLYRDI 
               
               
                   
               
               
                 TPKHGGLLGLLGLLNVKGKTFIGFITRDEWTASATVTDRIYKITDTEFYCINNDEYDYLLDKEYENMSHQER 
               
               
                   
               
               
                 ERLRYPAASVQRLLSSGAFYYSKQFDMTSNIQERGFVSSDYKLIADSSFFKSFMWNGFMTEELIETRKRMSP 
               
               
                   
               
               
                 AEQKIIDKSGLLIIVIRGYAKTVNTTVGGCEALMTLISKQSCAKEGPLFGDWGSDGDGYVSNYLESEIIIYT 
               
               
                   
               
               
                 EKFCLSYVIVRGNVPMYWELENNFSTKTILAANGKQIAFPRSFEASQEALVRHFDRLSSQYGDIHVLNTLSD 
               
               
                   
               
               
                 KSYKGVLNSAYEEQLKYFLQNRESTDIGYKVLYTRIPIASSRIKKIGYSGQNPYDIVSLLSNSIIDFGALFY 
               
               
                   
               
               
                 DSKPNSFIGKQLGVFRINSFDSLNKANFLSKIISQEVIDLAFRDIGLELDRELYVKHAQLWEENDLWISKLT 
               
               
                   
               
               
                 LNFASTSDKLHTSHNSIKSSFVKSHITKKYFGGVVESKPNEIAMLKLLGRLQDQSPVTMFNPIHNYVNKELN 
               
               
                   
               
               
                 KRAKDFTSKLDLSVYASTFNVNGSVYEGDIDKWIYPEENDYDLIFIGLQEIVVLNAGQMVNTDFRNKTQWER 
               
               
                   
               
               
                 KILGVLQKRNKYMVMWSGQLGGVALYFFVKESQVKYVSNVECSFKKTGLGGVSANKGGIAVSFKFSDTTICF 
               
               
                   
               
               
                 VSAHLAAGLSNIEERHQNYKALIKGIQFSKNRRIQNHDAVIWLGDFNYRIDLTNDQVKPMILQKLYAKIFEC 
               
               
                   
               
               
                 DQLNKQMANGESFPFFSEQEINFPPTYKFDKGTKVYDTSEKQRIPAWTDRILFLSRQNLIEPLSYNSCQNLT 
               
               
                   
               
               
                 FSDHRPVYATFKITVKIINHTIKKNLSDEIYKNYKDSHNGIFDILVKSFDNKELNEGKDASLPAPSSDKHKW 
               
               
                   
               
               
                 WLEGGKAAKIIIPGLEDDNMVMNPWRPINPFEKSNEPEFVSKNDLEAIQN 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 LYLIEKPRTFVITTNT 
                 3 
                 0.96 
               
               
                 2 
                 EQEINFPPTYKFDKGT 
                 810 
                 0.95 
               
               
                 3 
                 EGDIDKWIYPEENDYD 
                 603 
                 0.93 
               
               
                 4 
                 PGLEDDNMVMNPWRPI 
                 949 
                 0.92 
               
               
                 5 
                 EWTASATVTDRIYKIT 
                 101 
                 0.91 
               
               
                 6 
                 HPSPTYKHSGIKGLVS 
                 25 
                 0.90 
               
               
                 6 
                 GFMTEELIETRKRMSP 
                 201 
                 0.90 
               
               
                 7 
                 PFEKSNEPEFVSKNDL 
                 966 
                 0.89 
               
               
                 7 
                 IPAWTDRILFLSRQNL 
                 836 
                 0.89 
               
               
                 7 
                 SEIIIYTEKFCLSYVI 
                 282 
                 0.89 
               
               
                 7 
                 HALIIRHPSPTYKHSG 
                 19 
                 0.89 
               
               
                 8 
                 SCAKEGPLFGDWGSDG 
                 257 
                 0.88 
               
               
                 9 
                 LVSGHSKDKDQNKDTK 
                 38 
                 0.87 
               
               
                 9 
                 HSGIKGLVSGHSKDKD 
                 32 
                 0.87 
               
               
                 9 
                 EFYCINNDEYDYLLDK 
                 119 
                 0.87 
               
               
                 9 
                 RIYKITDTEFYCINND 
                 111 
                 0.87 
               
               
                 10 
                 AQLWEENDLWISKLTL 
                 490 
                 0.86 
               
               
                 10 
                 PLFGDWGSDGDGYVSN 
                 263 
                 0.86 
               
               
                 10 
                 GLLIIVIRGYAKTVNT 
                 226 
                 0.86 
               
               
                 11 
                 MVMWSGQLGGVALYFF 
                 661 
                 0.85 
               
               
                 11 
                 QSPVTMFNPIHNYVNK 
                 558 
                 0.85 
               
               
                 11 
                 SGAFYYSKQFDMTSNI 
                 160 
                 0.85 
               
               
                 12 
                 YKLIADSSFFKSFMWN 
                 185 
                 0.84 
               
               
                 13 
                 APSSDKHKWWLEGGKA 
                 928 
                 0.83 
               
               
                 13 
                 TKVYDTSEKQRIPAWT 
                 825 
                 0.83 
               
               
                 13 
                 KELNKRAKDFTSKLDL 
                 573 
                 0.83 
               
               
                 13 
                 GGVVESKPNEIAMLKL 
                 536 
                 0.83 
               
               
                 13 
                 KSHITKKYFGGVVESK 
                 527 
                 0.83 
               
               
                 13 
                 EYENMSHQERERLRYP 
                 135 
                 0.83 
               
               
                 14 
                 HDAVIWLGDFNYRIDL 
                 757 
                 0.82 
               
               
                 14 
                 GYSGQNPYDIVSLLSN 
                 407 
                 0.82 
               
               
                 15 
                 DEIYKNYKDSHNGIFD 
                 892 
                 0.81 
               
               
                 15 
                 ANKGGIAVSFKFSDTT 
                 702 
                 0.81 
               
               
                 15 
                 NAGQMVNTDFRNKTQW 
                 631 
                 0.81 
               
               
                 15 
                 HVLNTLSDKSYKGVLN 
                 353 
                 0.81 
               
               
                 15 
                 GKQIAFPRSFEASQEA 
                 322 
                 0.81 
               
               
                 16 
                 MNPWRPINPFEKSNEP 
                 958 
                 0.80 
               
               
                 16 
                 FIGFITRDEWTASATV 
                 93 
                 0.80 
               
               
                 16 
                 NRRIQNHDAVIWLGDF 
                 751 
                 0.80 
               
               
                 16 
                 ECSFKKTGLGGVSANK 
                 689 
                 0.80 
               
               
                 16 
                 IGLELDRELYVKHAQL 
                 477 
                 0.80 
               
               
                 17 
                 LNEGKDASLPAPSSDK 
                 918 
                 0.79 
               
               
                 17 
                 TVKIINHTIKKNLSDE 
                 878 
                 0.79 
               
               
                 17 
                 YVIVRGNVPMYWELEN 
                 295 
                 0.79 
               
               
                 17 
                 TFVITTNTHALIIRHP 
                 11 
                 0.79 
               
               
                 18 
                 RQNLIEPLSYNSCQNL 
                 848 
                 0.78 
               
               
                 18 
                 GVFRINSFDSLNKANF 
                 445 
                 0.78 
               
               
                 19 
                 KGIQFSKNRRIQNHDA 
                 744 
                 0.77 
               
               
                 19 
                 AASVQRLLSSGAFYYS 
                 151 
                 0.77 
               
               
                 20 
                 HKWWLEGGKAAKIIIP 
                 934 
                 0.76 
               
               
                 20 
                 IFDILVKSFDNKELNE 
                 905 
                 0.76 
               
               
                 20 
                 SSRIKKIGYSGQNPYD 
                 400 
                 0.76 
               
               
                 20 
                 FEASQEALVRHFDRLS 
                 331 
                 0.76 
               
               
                 20 
                 HQERERLRYPAASVQR 
                 141 
                 0.76 
               
               
                 21 
                 TFSDHRPVYATFKITV 
                 864 
                 0.75 
               
               
                 21 
                 NDLWISKLTLNFASTS 
                 496 
                 0.75 
               
               
                 21 
                 VGGCEALMTLISKQSC 
                 243 
                 0.75 
               
               
                 21 
                 TRKRMSPAEQKIIDKS 
                 210 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 281 
                 301 
                 295 
                 ESEIIIYTEKFCLSYVIVRGN 
               
               
                 52 
                 71 
                 57 
                 TKVLVEFVLKEYLDLSLYRD 
               
               
                 668 
                 693 
                 674 
                 LGGVALYFFVKESQVKYVSNVECSFK 
               
               
                 716 
                 729 
                 722 
                 TTICFVSAHLAAGL 
               
               
                 618 
                 633 
                 627 
                 DLIFIGLQEIVVLNAG 
               
               
                 224 
                 234 
                 229 
                 KSGLLIIVIRG 
               
               
                 414 
                 424 
                 417 
                 YDIVSLLSNSI 
               
               
                 76 
                 89 
                 85 
                 HGGLLGLLGLLNVK 
               
               
                 585 
                 595 
                 589 
                 KLDLSVYASTF 
               
               
                 388 
                 401 
                 390 
                 GYKVLYTRIPIASS 
               
               
                 482 
                 492 
                 489 
                 DRELYVKHAQL 
               
               
                 650 
                 656 
                 652 
                 ILGVLQK 
               
               
                 148 
                 167 
                 155 
                 RYPAASVQRLLSSGAFYYSK 
               
               
                 335 
                 357 
                 355 
                 QEALVRHFDRLSSQYGDIHVLNT 
               
               
                 905 
                 912 
                 908 
                 IFDILVKS 
               
               
                 778 
                 795 
                 784 
                 KPMILQKLYAKIFECDQL 
               
               
                 240 
                 262 
                 255 
                 NTTVGGCEALMTLISKQSCAKEG 
               
               
                 852 
                 863 
                 854 
                 IEPLSYNSCQNL 
               
               
                 706 
                 712 
                 710 
                 GIAVSFK 
               
               
                 548 
                 555 
                 549 
                 MLKLLGRL 
               
               
                 460 
                 476 
                 467 
                 FLSKIISQEVIDLAFRD 
               
               
                 757 
                 763 
                 760 
                 HDAVIWL 
               
               
                 372 
                 380 
                 377 
                 EEQLKYFLQ 
               
               
                 19 
                 33 
                 22 
                 HALIIRHPSPTYKHS 
               
               
                 535 
                 541 
                 536 
                 FGGVVES 
               
               
                 868 
                 884 
                 874 
                 HRPVYATFKITVKIINH 
               
               
                 523 
                 529 
                 527 
                 SSFVKSH 
               
               
                 841 
                 849 
                 846 
                 DRILFLSRQ 
               
               
                 441 
                 449 
                 446 
                 GKQLGVFRI 
               
               
                 178 
                 195 
                 184 
                 RGFVSSDYKLLADSSFFK 
               
               
                 557 
                 564 
                 558 
                 DQSPVTMF 
               
               
                 944 
                 950 
                 946 
                 AKIIIPG 
               
               
                 35 
                 42 
                 41 
                 IKGLVSGH 
               
               
                 363 
                 369 
                 364 
                 YKGVLNS 
               
               
                 924 
                 931 
                 927 
                 ASLPAPSS 
               
               
                 129 
                 134 
                 131 
                 DYLLDK 
               
               
                 739 
                 747 
                 745 
                 YKALIKGIQ 
               
               
                 426 
                 433 
                 427 
                 DFGALFYD 
               
               
                 10 
                 16 
                 11 
                 RTFVITT 
               
               
                 500 
                 508 
                 502 
                 ISKLTLNFA 
               
               
                 325 
                 330 
                 328 
                 IAFPRS 
               
               
                 315 
                 320 
                 317 
                 KTILAA 
               
               
                 105 
                 115 
                 111 
                 SATVTDRIYKI 
               
               
                 825 
                 830 
                 828 
                 TKVYDT 
               
               
                   
               
            
           
           
               
               
            
               
                 59. SET2 
                   
               
               
                 MSNNNFQESSNNTSSPSKRSTPMLFLDAENKTQEALTTFELLNACTYQNKYVGSANVTTTATTSTKTSNSTS 
               
               
                   
               
               
                 TKSHQQQHRRKLEYMTCDCEEEWDSELQMNLACGPDSNCINRITCVECVNRNCLCGDDCQNQRFQNRQYSKV 
               
               
                   
               
               
                 KVIQTELKGYGLIAEQDIEENQFIYEYIGEVIDEISFRQRMIEYDLRHLKHFYFMMLSNDSFIDATEKGSLG 
               
               
                   
               
               
                 RFINHSCNPNAFVDKWHVGDRLRMGIFAKRKISRGEEITFDYNVDRYGAQSQPCYCGEPNCIKFMGGKTQTD 
               
               
                   
               
               
                 AALLLPQMIAEALGVTPRQEKAWLKENKSIRNQQQNDESNINEEFVNSIEIEPIENQDGVTKVMSALMKTQH 
               
               
                   
               
               
                 PLIIKKLIERIFLSNDQDDINVMFVRFHGYKTISTILQDLLVAKNSGKESETTDNNDIDNSTGDDDQDKDEL 
               
               
                   
               
               
                 IIKILKILVSWPAVTKNKIASANLEEVVKDIQTNNENSNNNDEINQLCTSLLDRWSKLEMAYRIPKQESVPT 
               
               
                   
               
               
                 NNAAAAATTTATATGTTTSASPFERISSHTPEVGGTNTPSSTSQQQQQQNSRDAGLPENWRSAFDKNTGGYY 
               
               
                   
               
               
                 YYNLVTKETTWERPLGSLPLGPKPPSGPGLKGRINKYNEIDLAKREELRIQKEKEMKFIEMQNRDRKLKELI 
               
               
                   
               
               
                 EMSKKSMNNIGGSSGTTITAATINGLSDNGGNNNGNITGIYGDDKHSKHHHHHHDKHLKNGPRNTSTSSSSG 
               
               
                   
               
               
                 NNVEKIWKRIFAKYIPNIIKKYESEIGRDNVKGCAKELVNILTQSEIKHGNSLPSSSSSNGYSMELSDKKLK 
               
               
                   
               
               
                 KIKEYSHGYMDKFLIKFNNSKKHKSTMGSKGSDNHKRKHNGDGDNGVKRSKV* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 ACTYQNKYVGSANVTT 
                 44 
                 0.94 
               
               
                 2 
                 VKDIQTNNENSNNNDE 
                 460 
                 0.93 
               
               
                 2 
                 QRMIEYDLRHLKHFYF 
                 183 
                 0.93 
               
               
                 3 
                 HHHHDKHLKNGPRNTS 
                 699 
                 0.92 
               
               
                 3 
                 FERISSHTPEVGGTNT 
                 527 
                 0.92 
               
               
                 3 
                 KISRGEEITFDYNVDR 
                 247 
                 0.92 
               
               
                 4 
                 EEEWDSELQMNLACGP 
                 92 
                 0.91 
               
               
                 4 
                 KIKEYSHGYMDKFLIK 
                 793 
                 0.91 
               
               
                 4 
                 QESSNNTSSPSKRSTP 
                 7 
                 0.91 
               
               
                 4 
                 TGGYYYYNLVTKETTW 
                 572 
                 0.91 
               
               
                 4 
                 KFMGGKTQTDAALLLP 
                 279 
                 0.91 
               
               
                 4 
                 TEKGSLGRFINHSCNP 
                 210 
                 0.91 
               
               
                 5 
                 TINGLSDNGGNNNGNI 
                 670 
                 0.90 
               
               
                 5 
                 TPEVGGTNTPSSTSQQ 
                 534 
                 0.90 
               
               
                 5 
                 SGKESETTDNNDIDNS 
                 406 
                 0.90 
               
               
                 5 
                 GRFINHSCNPNAFVDK 
                 216 
                 0.90 
               
               
                 5 
                 DSFIDATEKGSLGRFI 
                 204 
                 0.90 
               
               
                 6 
                 YMTCDCEEEWDSELQM 
                 86 
                 0.89 
               
               
                 6 
                 SSNGYSMELSDKKLKK 
                 778 
                 0.89 
               
               
                 6 
                 MKFIEMQNRDRKLKEL 
                 632 
                 0.89 
               
               
                 6 
                 ANVTTTATTSTKTSNS 
                 55 
                 0.89 
               
               
                 6 
                 SQQQQQQNSRDAGLPE 
                 547 
                 0.89 
               
               
                 7 
                 LVTKETTWERPLGSLP 
                 580 
                 0.87 
               
               
                 7 
                 YGAQSQPCYCGEPNCI 
                 263 
                 0.87 
               
               
                 7 
                 KWHVGDRLRMGIFAKR 
                 231 
                 0.87 
               
               
                 8 
                 KYESEIGRDNVKGCAK 
                 741 
                 0.86 
               
               
                 8 
                 KHSKHHHHHHDKHLKN 
                 693 
                 0.86 
               
               
                 8 
                 SKLEMAYRIPKQESVP 
                 488 
                 0.86 
               
               
                 8 
                 IGEVIDEISFRQRMIE 
                 172 
                 0.86 
               
               
                 9 
                 IPNIIKKYESEIGRDN 
                 735 
                 0.85 
               
               
                 9 
                 KGRINKYNEIDLAKRE 
                 607 
                 0.85 
               
               
                 9 
                 NSIEIEPIENQDGVTK 
                 335 
                 0.85 
               
               
                 9 
                 EALGVTPRQEKAWLKE 
                 299 
                 0.85 
               
               
                 10 
                 NHKRKHNGDGDNGVKR 
                 826 
                 0.84 
               
               
                 10 
                 NGPRNTSTSSSSGNNV 
                 708 
                 0.84 
               
               
                 10 
                 TSTKTSNSTSTKSHQQ 
                 63 
                 0.84 
               
               
                 10 
                 PLIIKKLIERIFLSND 
                 361 
                 0.84 
               
               
                 11 
                 MGSKGSDNHKRKHNGD 
                 819 
                 0.83 
               
               
                 11 
                 AWLKENKSIRNQQQND 
                 310 
                 0.83 
               
               
                 11 
                 MNLACGPDSNCINRIT 
                 101 
                 0.83 
               
               
                 12 
                 NSTGDDDQDKDELIIK 
                 420 
                 0.82 
               
               
                 13 
                 TSTKSHQQQHRRKLEY 
                 71 
                 0.81 
               
               
                 13 
                 SGTTITAATINGLSDN 
                 662 
                 0.81 
               
               
                 13 
                 KPPSGPGLKGRINKYN 
                 599 
                 0.81 
               
               
                 13 
                 RPLGSLPLGPKPPSGP 
                 589 
                 0.81 
               
               
                 13 
                 TATGTTTSASPFERIS 
                 516 
                 0.81 
               
               
                 13 
                 IPKQESVPTNNAAAAA 
                 496 
                 0.81 
               
               
                 13 
                 NCINRITCVECVNRNC 
                 110 
                 0.81 
               
               
                 14 
                 NNSKKHKSTMGSKGSD 
                 810 
                 0.80 
               
               
                 15 
                 NGNITGIYGDDKHSKH 
                 682 
                 0.79 
               
               
                 15 
                 ECVNRNCLCGDDCQNQ 
                 119 
                 0.79 
               
               
                 16 
                 PCYCGEPNCIKFMGGK 
                 269 
                 0.78 
               
               
                 17 
                 QNSRDAGLPENWRSAF 
                 553 
                 0.77 
               
               
                 17 
                 MSALMKTQHPLIIKKL 
                 352 
                 0.77 
               
               
                 18 
                 KELIEMSKKSMNNIGG 
                 645 
                 0.76 
               
               
                 18 
                 YKTISTILQDLLVAKN 
                 390 
                 0.76 
               
               
                 18 
                 SKRSTPMLFLDAENKT 
                 17 
                 0.76 
               
               
                 18 
                 IQTELKGYGLIAEQDI 
                 147 
                 0.76 
               
               
                 19 
                 NILTQSEIKHGNSLPS 
                 760 
                 0.75 
               
               
                 19 
                 NAAAAATTTATATGTT 
                 506 
                 0.75 
               
               
                 19 
                 NKTQEALTTFELLNAC 
                 30 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 112 
                 130 
                 118 
                 INRITCVECVNRNCLCGDD 
               
               
                 393 
                 405 
                 399 
                 ISTILQDLLVAKN 
               
               
                 431 
                 449 
                 439 
                 ELIIKILKILVSWPAVTKN 
               
               
                 477 
                 487 
                 481 
                 NQLCTSLLDRW 
               
               
                 265 
                 280 
                 269 
                 AQSQPCYCGEPNCIKF 
               
               
                 575 
                 583 
                 578 
                 YYYYNLVTK 
               
               
                 288 
                 306 
                 292 
                 DAALLLPQMIAEALGVTPR 
               
               
                 141 
                 151 
                 144 
                 YSKVKVIQTEL 
               
               
                 38 
                 55 
                 44 
                 TFELLNACTYQNKYVGSA 
               
               
                 356 
                 374 
                 365 
                 MKTQHPLIIKKLIERIFLS 
               
               
                 591 
                 599 
                 593 
                 LGSLPLGPK 
               
               
                 751 
                 766 
                 756 
                 VKGCAKELVNILTQSE 
               
               
                 382 
                 388 
                 385 
                 VMFVRFH 
               
               
                 187 
                 199 
                 195 
                 EYDLRHLKHFYFM 
               
               
                 224 
                 232 
                 231 
                 NPNAFVDKW 
               
               
                 456 
                 463 
                 462 
                 LEEVVKDI 
               
               
                 731 
                 739 
                 733 
                 FAKYIPNII 
               
               
                 100 
                 110 
                 102 
                 QMNLACGPDSN 
               
               
                 168 
                 179 
                 169 
                 IYEYIGEVIDEI 
               
               
                 695 
                 705 
                 699 
                 SKHHHHHHDKH 
               
               
                 348 
                 354 
                 351 
                 VTKVMSA 
               
               
                 153 
                 159 
                 154 
                 GYGLIAE 
               
               
                 86 
                 92 
                 88 
                 YMTCDCE 
               
               
                 22 
                 27 
                 25 
                 PMLFLD 
               
               
                 770 
                 776 
                 775 
                 GNSLPSS 
               
               
                 257 
                 263 
                 257 
                 DYNVDRY 
               
               
                 803 
                 809 
                 806 
                 DKFLIKF 
               
               
                 791 
                 800 
                 794 
                 LKKIKEYSHG 
               
               
                 524 
                 530 
                 527 
                 ASPFERI 
               
               
                   
               
            
           
           
               
               
            
               
                 60. DOT1 
                   
               
               
                 MISGHLQTPDSSDHSGDEAKLTKPSGLESKTNELWSSDLEEELESRIMQPATFSSILKQFPSISEETIISKI 
               
               
                   
               
               
                 MSNKNCDKNNWKKKIYCYRYFLQPSKEEPDVGNMKSLVEKLEKLKLKKWSASEIEQLFCNYLEDLTTSAVKV 
               
               
                   
               
               
                 SIPGKTLDEVAAAVNNIHPRPRWTRKEIECLIKNENDFKKLEKDLFVRDLDSIKKKIRRDNLSIQNEIQDSE 
               
               
                   
               
               
                 KKSPQSTDSNNKDSSRDLSRKERDQLKKLLSKPICFSELLAKFPGHSWEYIAREIIQLDSSEDNTIWLKKIY 
               
               
                   
               
               
                 YYCVVYSISVDKEITKYIGGGNRIYEKVRSDWSKIKTLDFFKDWSLQEFERLYCFAFHDLTKSALTKNFPSK 
               
               
                   
               
               
                 NLNDICKVVNISFPKVPYTDREMKYLERHLDTPMQTLENNLPFRSRGSIHKKLEALKALTETTEQKQPPTKT 
               
               
                   
               
               
                 RPKNEEEKNVENAAYMKELIMFDLTLEAIENTFPSEPIEEIIKEIKNSEIFDPLSFTRGEKELMAKLVKKGN 
               
               
                   
               
               
                 LIDDCFDYFPLREEEFIRSKYAEAEYVSGRKMKFNTPEERLAYEAKWTLFNMGKQEYGRGNRRSTKRYCE ID 
               
               
                   
               
               
                 ELSKLEQEASVKRSKKKIELTEEELEQRRKRSEHFRLCRLKKLEEKREKYRIEKAKRLEKIAAGLIKPSTSG 
               
               
                   
               
               
                 YELKDIVTSAEYFQSIVGDKQKVQEGQKRKRIQTEYFAPEFIEKPKAVKLKTTKRQAEKNKIKKQLKREAQL 
               
               
                   
               
               
                 KIKKKKTIAPKKGKRRVKTNNGIIEEIKDVYKLSSEPYVESEVEEEDEEEDYISPYDPPDIISDSQVKLNGR 
               
               
                   
               
               
                 HLYISSFYKELPEIPELKFVSLPHMEMSGNDITVAKQIMTTANDDILYDDCLAYEIVAQHIKSYRDLFISVP 
               
               
                   
               
               
                 PVLDPITHELNSANIVRIRFFLYPEHYESFMLASPKSNELDPVHEIAKLFMIQYSLYFSHSDTLKKIITEDY 
               
               
                   
               
               
                 CHKLEHSVEENDFGEFMFVVDKWNQLVMKLSPNLASVQNILGLKEDINEAPRAYLNQQEVSIPTNSDLKIET 
               
               
                   
               
               
                 FYDEIMYESASPLFNPINSNLEIDSESAPIPLGEVEIPNNVIEEINEKMPDNYIPDFFRRLKEKTEVSRYAM 
               
               
                   
               
               
                 QQILLRVYSRVVSTDSRKLRSYKAFTAETYGELLPSFTSEVLEKLNLLPTQKFYDLGSGVGNTTFQAALEFG 
               
               
                   
               
               
                 ACSSGGCEIMEHASKLTELQAGLIQKHLAVLGLQKLNLDFALHESFVGNEKVRASCLDCDVLIINNYLFDGQ 
               
               
                   
               
               
                 LNDEVGKLLYGLRPGTKIVSLRNFISPRYRATFDTVFDFLSVEKHEMSDIMSVSWTANKVPYYISTVEETIP 
               
               
                   
               
               
                 REYLSREETKETSGKSKSVSPVGEIENVAAAMMTPPTDSSESEIIKN* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 EETIISKIMSNKNCDK 
                 65 
                 0.95 
               
               
                 1 
                 SGHLQTPDSSDHSGDE 
                 3 
                 0.95 
               
               
                 2 
                 KELIMFDLTLEAIENT 
                 449 
                 0.94 
               
               
                 2 
                 DVLIINNYLFDGQLND 
                 1212 
                 0.94 
               
               
                 3 
                 SVEENDFGEFMFVVDK 
                 943 
                 0.93 
               
               
                 4 
                 LFMIQYSLYFSHSDTL 
                 913 
                 0.92 
               
               
                 4 
                 KSYRDLPISFPPVLDP 
                 854 
                 0.92 
               
               
                 5 
                 AAGLIKPSTSGYELKD 
                 638 
                 0.91 
               
               
                 5 
                 TTEQKQPPTKTRPKNE 
                 422 
                 0.91 
               
               
                 5 
                 DKEITKYIGGGNRIYE 
                 299 
                 0.91 
               
               
                 6 
                 TEDYCHKLEHSVEEND 
                 933 
                 0.89 
               
               
                 6 
                 DEEEDYISPYDPPDII 
                 767 
                 0.89 
               
               
                 7 
                 KQEYGRGNRRSTKRYC 
                 558 
                 0.88 
               
               
                 7 
                 ESRIMQPATFSSILKQ 
                 44 
                 0.88 
               
               
                 7 
                 RGSIHKKLEALKALTE 
                 406 
                 0.88 
               
               
                 8 
                 YFLQPSKEEPDVGNMK 
                 92 
                 0.87 
               
               
                 8 
                 NSEIFDPLSFTRGEKE 
                 479 
                 0.87 
               
               
                 8 
                 IMYESASPLFNPINSN 
                 1013 
                 0.87 
               
               
                 9 
                 GLKEDINEAPRAYLNQ 
                 978 
                 0.86 
               
               
                 9 
                 DILYDDCLAYEIVAQH 
                 837 
                 0.86 
               
               
                 9 
                 SGRKMKFNTPEERLAY 
                 532 
                 0.86 
               
               
                 9 
                 YTDREMKYLERHLDTP 
                 378 
                 0.86 
               
               
                 9 
                 TKSALTKNFPSKNLND 
                 349 
                 0.86 
               
               
                 9 
                 PGHSWEYIAREIIQLD 
                 260 
                 0.86 
               
               
                 10 
                 FFLYPEHYESFMLASP 
                 884 
                 0.85 
               
               
                 10 
                 APEFIEKPKAVKLKTT 
                 686 
                 0.85 
               
               
                 10 
                 AEAEYVSGRKMKFNTP 
                 526 
                 0.85 
               
               
                 10 
                 GNRIYEKVRSDWSKIK 
                 309 
                 0.85 
               
               
                 10 
                 TVEETIPREYLSREET 
                 1290 
                 0.85 
               
               
                 11 
                 YESFMLASPKSNELDP 
                 891 
                 0.84 
               
               
                 11 
                 AGLIQKHLAVLGLQKL 
                 1173 
                 0.84 
               
               
                 11 
                 FNPINSNLEIDSESAP 
                 1022 
                 0.84 
               
               
                 12 
                 KKKTIAPKKGKRRVKT 
                 724 
                 0.83 
               
               
                 12 
                 KRIQTEYFAPEFIEKP 
                 678 
                 0.83 
               
               
                 12 
                 FNTPEERLAYEAKWTL 
                 538 
                 0.83 
               
               
                 12 
                 IEEIIKEIKNSEIFDP 
                 470 
                 0.83 
               
               
                 12 
                 MQTLENNLPFRSRGSI 
                 394 
                 0.83 
               
               
                 12 
                 REIIQLDSSEDNTIWL 
                 269 
                 0.83 
               
               
                 12 
                 QNEIQDSEKKSPQSTD 
                 209 
                 0.83 
               
               
                 12 
                 SVSWTANKVPYYISTV 
                 1276 
                 0.83 
               
               
                 12 
                 EMSDIMSVSWTANKVP 
                 1270 
                 0.83 
               
               
                 12 
                 MQQILLRVYSRVVSTD 
                 1080 
                 0.83 
               
               
                 13 
                 AKQIMTTANDDILYDD 
                 827 
                 0.82 
               
               
                 13 
                 SEVEEEDEEEDYISPY 
                 761 
                 0.82 
               
               
                 13 
                 KDIVTSAEYFQSIVGD 
                 652 
                 0.82 
               
               
                 13 
                 KKLEEKREKYRIEKAK 
                 617 
                 0.82 
               
               
                 13 
                 SFTRGEKELMAKLVKK 
                 487 
                 0.82 
               
               
                 13 
                 KKIYYYCVVYSISVDK 
                 285 
                 0.82 
               
               
                 13 
                 KKSPQSTDSNNKDSSR 
                 217 
                 0.82 
               
               
                 13 
                 ECLIKNENDFKKLEKD 
                 173 
                 0.82 
               
               
                 13 
                 AFTAETYGELLPSFTS 
                 1104 
                 0.82 
               
               
                 13 
                 VIEEINEKMPDNYIPD 
                 1049 
                 0.82 
               
               
                 14 
                 YCEIDELSKLEQEASV 
                 572 
                 0.81 
               
               
                 14 
                 AAVNNIHPRPRWTRKE 
                 156 
                 0.81 
               
               
                 14 
                 SLRNFISPRYRATFDT 
                 1244 
                 0.81 
               
               
                 14 
                 LGSGVGNTTFQAALEF 
                 1136 
                 0.81 
               
               
                 15 
                 EMSGNDITVAKQIMTT 
                 818 
                 0.80 
               
               
                 15 
                 HSGDEAKLTKPSGLES 
                 14 
                 0.80 
               
               
                 15 
                 SPVGEIENVAAAMMTP 
                 1316 
                 0.80 
               
               
                 15 
                 RYRATFDTVFDFLSVE 
                 1252 
                 0.80 
               
               
                 15 
                 GCEIMEHASKLTELQA 
                 1158 
                 0.80 
               
               
                 15 
                 GACSSGGCEIMEHASK 
                 1152 
                 0.80 
               
               
                 16 
                 NQLVMKLSPNLASVQN 
                 960 
                 0.79 
               
               
                 16 
                 NNWKKKIYCYRYFLQP 
                 81 
                 0.79 
               
               
                 16 
                 PDIISDSQVKLNGRHL 
                 779 
                 0.79 
               
               
                 16 
                 KLEQEASVKRSKKKIE 
                 580 
                 0.79 
               
               
                 16 
                 GNLIDDCFDYFPLREE 
                 503 
                 0.79 
               
               
                 16 
                 DWSKIKTLDFFKDWSL 
                 319 
                 0.79 
               
               
                 16 
                 LGEVEIPNNVIEEINE 
                 1040 
                 0.79 
               
               
                 17 
                 MFVVDKWNQLVMKLSP 
                 953 
                 0.78 
               
               
                 17 
                 FPPVLDPITHELNSAN 
                 863 
                 0.78 
               
               
                 17 
                 KQKVQEGQKRKRIQTE 
                 668 
                 0.78 
               
               
                 17 
                 IELTEEELEQRRKRSE 
                 594 
                 0.78 
               
               
                 17 
                 VAAAMMTPPTDSSESE 
                 1324 
                 0.78 
               
               
                 17 
                 EETKETSGKSKSVSPV 
                 1303 
                 0.78 
               
               
                 18 
                 NGIIEEIKDVYKLSSE 
                 741 
                 0.77 
               
               
                 18 
                 KAVKLKTTKRQAEKNK 
                 694 
                 0.77 
               
               
                 18 
                 NFPSKNLNDICKVVNI 
                 356 
                 0.77 
               
               
                 18 
                 RVVSTDSRKLRSYKAF 
                 1090 
                 0.77 
               
               
                 19 
                 KSNELDPVHEIAKLFM 
                 900 
                 0.76 
               
               
                 19 
                 KNKIKKQLKREAQLKI 
                 707 
                 0.76 
               
               
                 19 
                 KYLERHLDTPMQTLEN 
                 384 
                 0.76 
               
               
                 19 
                 YCFAFHDLTKSALTKN 
                 341 
                 0.76 
               
               
                 19 
                 SIPGKTLDEVAAAVNN 
                 145 
                 0.76 
               
               
                 20 
                 NGRHLYISSFYKELPE 
                 790 
                 0.75 
               
               
                 20 
                 KNEEEKNVENAAYMKE 
                 435 
                 0.75 
               
               
                 20 
                 NNKDSSRDLSRKERDQ 
                 226 
                 0.75 
               
               
                 20 
                 NTTFQAALEFGACSSG 
                 1142 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 284 
                 301 
                 291 
                 LKKIYYYCVVYSISVDKE 
               
               
                 1205 
                 1219 
                 1211 
                 RASCLDCDVLIINNY 
               
               
                 839 
                 873 
                 846 
                 LYDDCLAYEIVAQHIKSYRDLPISFPPVLDPITHE 
               
               
                 1080 
                 1094 
                 1090 
                 MQQILLRVYSRVVST 
               
               
                 363 
                 379 
                 368 
                 NDICKVVNISFPKVPYT 
               
               
                 1165 
                 1198 
                 1182 
                 ASKLTELQAGLIQKHLAVLGLQKLNLDFALHESF 
               
               
                 337 
                 352 
                 343 
                 FERLYCFAFHDLTKSA 
               
               
                 86 
                 96 
                 91 
                 KIYCYRYFLQP 
               
               
                 1257 
                 1267 
                 1263 
                 FDTVFDFLSVE 
               
               
                 242 
                 260 
                 248 
                 LKKLLSKPICFSELLAKFP 
               
               
                 139 
                 149 
                 144 
                 TSAVKVSIPGK 
               
               
                 773 
                 815 
                 812 
                 ISPYDPPDIISDSQVKLNGRHLYISSFYKELPEIPEL 
               
               
                   
                   
                   
                 KFVSLP 
               
               
                 126 
                 137 
                 131 
                 IEQLFCNYLEDL 
               
               
                 506 
                 515 
                 512 
                 IDDCFDYFPL 
               
               
                 610 
                 617 
                 616 
                 HFRLCRLK 
               
               
                 1282 
                 1294 
                 1286 
                 NKVPYYISTVEET 
               
               
                 904 
                 931 
                 919 
                 LDPVHEIAKLFMIQYSLYFSHSDTLKKI 
               
               
                 933 
                 943 
                 939 
                 TEDYCHKLEHS 
               
               
                 1312 
                 1319 
                 1315 
                 SKSVSPVG 
               
               
                 747 
                 762 
                 756 
                 IKDVYKLSSEPYVESE 
               
               
                 1230 
                 1237 
                 1232 
                 GKLLYGLR 
               
               
                 952 
                 980 
                 965 
                 FMFVVDKWNQLVMKLSPNLASVQNILGLK 
               
               
                 877 
                 891 
                 883 
                 ANIVRIRFFLYPEHY 
               
               
                 1111 
                 1139 
                 1124 
                 GELLPSFTSEVLEKLNLLPTQKFYDLGSG 
               
               
                 651 
                 669 
                 663 
                 LKDIVTSAEYFQSIVGDKQ 
               
               
                 151 
                 161 
                 155 
                 LDEVAAAVNNI 
               
               
                 1146 
                 1159 
                 1156 
                 QAALEFGACSSGGC 
               
               
                 410 
                 419 
                 416 
                 HKKLEALKAL 
               
               
                 1034 
                 1043 
                 1040 
                 ESAPIPLGEV 
               
               
                 496 
                 503 
                 498 
                 MAKLVKKG 
               
               
                 186 
                 194 
                 188 
                 EKDLFVRDL 
               
               
                 106 
                 113 
                 110 
                 MKSLVEKL 
               
               
                 824 
                 829 
                 827 
                 ITVAKQ 
               
               
                 172 
                 177 
                 173 
                 IECLIK 
               
               
                 692 
                 699 
                 695 
                 KPKAVKLK 
               
               
                 570 
                 576 
                 575 
                 KRYCEID 
               
               
                 1239 
                 1248 
                 1245 
                 GTKIVSLRNF 
               
               
                 527 
                 533 
                 528 
                 EAEYVSG 
               
               
                 483 
                 488 
                 485 
                 FDPLSF 
               
               
                 52 
                 63 
                 59 
                 TFSSILKQFPSI 
               
               
                 988 
                 999 
                 996 
                 RAYLNQQEVSIP 
               
               
                 634 
                 644 
                 639 
                 LEKIAAGLIKP 
               
               
                 268 
                 275 
                 274 
                 AREIIQLD 
               
               
                 584 
                 589 
                 584 
                 EASVKR 
               
               
                 1018 
                 1024 
                 1018 
                 ASPLFNP 
               
               
                 115 
                 121 
                 115 
                 KLKLKKW 
               
               
                 1099 
                 1105 
                 1102 
                 LRSYKAF 
               
               
                 453 
                 459 
                 454 
                 MFDLTLE 
               
               
                 893 
                 899 
                 896 
                 SFMLASP 
               
               
                 4 
                 9 
                 5 
                 GHLQTP 
               
               
                 323 
                 328 
                 326 
                 IKTLDF 
               
               
                 1274 
                 1279 
                 1275 
                 IMSVSW 
               
               
                   
               
            
           
           
               
               
            
               
                 61. ENO1 
                   
               
               
                 MSYATKIHARYVYDSRGNPTVEVDFTTDKGLFRSIVPSGASTGVHEALELRDGDKSKWLGKGVLKAVANVND 
               
               
                   
               
               
                 IIAPALIKAKIDVVDQAKIDEFLLSLDGTPNKSKLGANAILGVSLAAANAAAAAQGIPLYKHIANISNAKKG 
               
               
                   
               
               
                 KFVLPVPFQNVLNGGSHAGGALAFQEFMIAPTGVSTFSEALRIGSEVYHNLKSLTKKKYGQSAGNVGDEGGV 
               
               
                   
               
               
                 APDIKTPKEALDLIMDAIDKAGYKGKVGIAMDVASSEFYKDGKYDLDFKNPESDPSKWLSGPQLADLYEQLI 
               
               
                   
               
               
                 SEYPIVSIEDPFAEDDWDAWVHFFERVGDKIQIVGDDLTVTNPTRIKTAIEKKAANALLLKVNQIGTLTESI 
               
               
                   
               
               
                 QAANDSYAAGWGVMVSHRSGETEDTFIADLSVGLRSGQIKTGAPARSERLAKLNQILRIEEELGSEAIYAGK 
               
               
                   
               
               
                 DFQKASQL 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 ATKIHARYVYDSRGNP 
                 4 
                 0.97 
               
               
                 2 
                 TESIQAANDSYAAGWG 
                 357 
                 0.94 
               
               
                 3 
                 HRSGETEDTFIADLSV 
                 377 
                 0.93 
               
               
                 4 
                 AAAAQGIPLYKHIANI 
                 123 
                 0.90 
               
               
                 5 
                 IVSIEDPFAEDDWDAW 
                 293 
                 0.89 
               
               
                 6 
                 SEAIYAGKDFQKASQL 
                 425 
                 0.88 
               
               
                 6 
                 EDDWDAWVHFFERVGD 
                 302 
                 0.88 
               
               
                 7 
                 GGVAPDIKTPKEALDL 
                 214 
                 0.87 
               
               
                 8 
                 LSLDGTPNKSKLGANA 
                 96 
                 0.85 
               
               
                 8 
                 KWLGKGVLKAVANVND 
                 57 
                 0.85 
               
               
                 8 
                 VDFTTDKGLFRSIVPS 
                 23 
                 0.85 
               
               
                 9 
                 AAGWGVMVSHRSGETE 
                 368 
                 0.84 
               
               
                 9 
                 GNVGDEGGVAPDIKTP 
                 208 
                 0.84 
               
               
                 10 
                 PALIKAKIDVVDQAKI 
                 76 
                 0.81 
               
               
                 10 
                 YKDGKYDLDFKNPESD 
                 255 
                 0.81 
               
               
                 11 
                 VHEALELRDGDKSKWL 
                 44 
                 0.79 
               
               
                 11 
                 GQIKTGAPARSERLAK 
                 397 
                 0.79 
               
               
                 11 
                 LDLIMDAIDKAGYKGK 
                 227 
                 0.79 
               
               
                 11 
                 KYGQSAGNVGDEGGVA 
                 202 
                 0.79 
               
               
                 11 
                 RYVYDSRGNPTVEVDF 
                 10 
                 0.79 
               
               
                 12 
                 VNQIGTLTESIQAAND 
                 350 
                 0.78 
               
               
                 13 
                 PTRIKTAIEKKAANAL 
                 331 
                 0.76 
               
               
                 13 
                 KGKFVLPVPFQNVLNG 
                 143 
                 0.76 
               
               
                 14 
                 VNDIIAPALIKAKIDV 
                 70 
                 0.75 
               
               
                 14 
                 GKVGIAMDVASSEFYK 
                 241 
                 0.75 
               
               
                 14 
                 ALRIGSEVYHNLKSLT 
                 184 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 144 
                 155 
                 149 
                 GKFVLPVPFQNV 
               
               
                 109 
                 137 
                 114 
                 ANAILGVSLAAANAAAAAQGIPLYKHIAN 
               
               
                 60 
                 89 
                 65 
                 GKGVLKAVANVNDIIAPALIKAKIDVVDQA 
               
               
                 343 
                 353 
                 347 
                 ANALLLKVNQI 
               
               
                 4 
                 14 
                 10 
                 ATKIHARYVYD 
               
               
                 32 
                 39 
                 34 
                 FRSIVPSG 
               
               
                 387 
                 397 
                 389 
                 IADLSVGLRSG 
               
               
                 307 
                 314 
                 312 
                 AWVHFFER 
               
               
                 272 
                 298 
                 291 
                 SKWLSGPQLADLYEQLISEYPIVSIED 
               
               
                 41 
                 50 
                 47 
                 STGVHEALEL 
               
               
                 175 
                 198 
                 194 
                 PTGVSTFSEALRIGSEVYHNLKSL 
               
               
                 372 
                 378 
                 376 
                 GVMVSHR 
               
               
                 92 
                 99 
                 97 
                 DEFLLSLD 
               
               
                 240 
                 253 
                 252 
                 KGKVGIAMDVASSE 
               
               
                 317 
                 326 
                 325 
                 DKIQIVGDDL 
               
               
                 412 
                 418 
                 416 
                 KLNQILR 
               
               
                 163 
                 172 
                 168 
                 GGALAFQEFM 
               
               
                 425 
                 432 
                 426 
                 SEAIYAGK 
               
               
                 226 
                 232 
                 227 
                 ALDLIMD 
               
               
                   
               
            
           
           
               
               
            
               
                 62. BGL2 
                   
               
               
                 MQIKFLTTLATVLTSVAAMGDLAFNLGVKNDDGTCKDVSTFEGDLDFLKSHSKIIKTYAVSDCNTLQNLGPA 
               
               
                   
               
               
                 AEAEGFQIQLGIWPNDDAHFEAEKEALQNYLPKISVSTIKIFLVGSEALYREDLTASELASKINDIKDLVKG 
               
               
                   
               
               
                 IKDKNGKSYSSVPVGTVDSWNVLVDGASKPAIDAADVVYSNSFSYWQKNSQANASYSLFDDVMQALQTLQTA 
               
               
                   
               
               
                 KGSTDIEFWVGETGWPTDGSSYGDSVPSVENAADQWQKGICALRAWGINVAVYEAFDEAWKPDTSGTSSVEK 
               
               
                   
               
               
                 HWGVWQSDKTLKYSIDCKF 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 SVAAMGDLAFNLGVKN 
                 15 
                 0.93 
               
               
                 2 
                 DGTCKDVSTFEGDLDF 
                 32 
                 0.91 
               
               
                 3 
                 SKIIKTYAVSDCNTLQ 
                 52 
                 0.89 
               
               
                 4 
                 AWKPDTSGTSSVEKHW 
                 275 
                 0.88 
               
               
                 5 
                 PSVENAADQWQKGICA 
                 243 
                 0.87 
               
               
                 5 
                 VGETGWPTDGSSYGDS 
                 226 
                 0.87 
               
               
                 6 
                 GFQIQLGIWPNDDAHF 
                 77 
                 0.86 
               
               
                 7 
                 YEAFDEAWKPDTSGTS 
                 269 
                 0.82 
               
               
                 7 
                 TAKGSTDIEFWVGETG 
                 215 
                 0.82 
               
               
                 8 
                 KPAIDAADVVYSNSFS 
                 173 
                 0.81 
               
               
                 9 
                 VGTVDSWNVLVDGASK 
                 158 
                 0.80 
               
               
                 9 
                 VKGIKDKNGKSYSSVP 
                 142 
                 0.80 
               
               
                 10 
                 QKGICALRAWGINVAV 
                 253 
                 0.79 
               
               
                 10 
                 ASKINDIKDLVKGIKD 
                 132 
                 0.79 
               
               
                 11 
                 ASYSLFDDVMQALQTL 
                 198 
                 0.78 
               
               
                 11 
                 LVGSEALYREDLTASE 
                 115 
                 0.78 
               
               
                 12 
                 SGTSSVEKHWGVWQSD 
                 281 
                 0.77 
               
               
                 13 
                 GKSYSSVPVGTVDSWN 
                 150 
                 0.76 
               
               
                 14 
                 WGVWQSDKTLKYSIDC 
                 290 
                 0.75 
               
               
                 14 
                 LGVKNDDGTCKDVSTF 
                 26 
                 0.75 
               
               
                 14 
                 NVLVDGASKPAIDAAD 
                 165 
                 0.75 
               
               
                 14 
                 REDLTASELASKINDI 
                 123 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 4 
                 21 
                 15 
                 KFLTTLATVLTSVAAMGD 
               
               
                 153 
                 161 
                 155 
                 YSSVPVGTV 
               
               
                 263 
                 271 
                 269 
                 GINVAVYEA 
               
               
                 99 
                 121 
                 105 
                 LQNYLPKISVSTIKIFLVGSEAL 
               
               
                 173 
                 186 
                 181 
                 KPAIDAADVVYSNS 
               
               
                 163 
                 171 
                 169 
                 SWNVLVDGA 
               
               
                 45 
                 66 
                 60 
                 LDFLKSHSKIIKTYAVSDCNTL 
               
               
                 298 
                 304 
                 302 
                 TLKYSID 
               
               
                 254 
                 261 
                 259 
                 KGICALRA 
               
               
                 197 
                 214 
                 203 
                 NASYSLFDDVMQALQTLQ 
               
               
                 239 
                 248 
                 242 
                 GDSVPSVENA 
               
               
                 78 
                 84 
                 81 
                 FQIQLGI 
               
               
                 128 
                 134 
                 129 
                 ASELASK 
               
               
                 139 
                 145 
                 141 
                 KDLVKGI 
               
               
                   
               
            
           
           
               
               
            
               
                 63. FBA1 
                   
               
               
                 MAPPAVLSKSGVIYGKDVKDLFDYAQEKGFAIPAINVTSSSTVVAALEAARDNKAPIILQTSQGGAAYFAGK 
               
               
                   
               
               
                 GVDNKDQAASIAGSIAAAHYIRAIAPTYGIPVVLHTDHCAKKLLPWFDGMLKADEEFFAKTGTPLFSSHMLD 
               
               
                   
               
               
                 LSEETDDENIATCAKYFERMAKMGQWLEMEIGITGGEEDGVNNEHVEKDALYTSPETVFAVYESLHKISPNF 
               
               
                   
               
               
                 SIAAAFGNVHGVYKPGNVQLRPEILGDHQVYAKKQIGTDAKHPLYLVFHGGSGSTQEEFNTAIKNGVVKVNL 
               
               
                   
               
               
                 DTDCQYAYLTGIRDYVTNKIEYLKAPVGNPEGADKPNKKYFDPRVWVREGEKTMSKRIAEALDIFHTKGQL* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 TSQGGAAYFAGKGVDN 
                 61 
                 0.92 
               
               
                 2 
                 PETVFAVYESLHKISP 
                 199 
                 0.90 
               
               
                 2 
                 DGVNNEHVEKDALYTS 
                 183 
                 0.90 
               
               
                 3 
                 AGSIAAAHYIRAIAPT 
                 84 
                 0.89 
               
               
                 3 
                 EMEIGITGGEEDGVNN 
                 172 
                 0.89 
               
               
                 3 
                 DGMLKADEEFFAKTGT 
                 120 
                 0.89 
               
               
                 4 
                 GGSGSTQEEFNTAIKN 
                 266 
                 0.87 
               
               
                 5 
                 TDCQYAYLTGIRDYVT 
                 290 
                 0.84 
               
               
                 5 
                 HCAKKLLPWFDGMLKA 
                 110 
                 0.84 
               
               
                 6 
                 VGNPEGADKPNKKYFD 
                 315 
                 0.83 
               
               
                 6 
                 DLSEETDDENIATCAK 
                 144 
                 0.83 
               
               
                 7 
                 KKQIGTDAKHPLYLVF 
                 249 
                 0.82 
               
               
                 8 
                 AVLSKSGVIYGKDVKD 
                 5 
                 0.81 
               
               
                 9 
                 YIRAIAPTYGIPVVLH 
                 92 
                 0.80 
               
               
                 9 
                 NKKYFDPRVWVREGEK 
                 325 
                 0.80 
               
               
                 10 
                 AAFGNVHGVYKPGNVQ 
                 220 
                 0.79 
               
               
                 10 
                 ATCAKYFERMAKMGQW 
                 155 
                 0.79 
               
               
                 11 
                 EGEKTMSKRIAEALDI 
                 337 
                 0.78 
               
               
                 11 
                 RPEILGDHQVYAKKQI 
                 237 
                 0.78 
               
               
                 12 
                 NTAIKNGVVKVNLDTD 
                 276 
                 0.77 
               
               
                 12 
                 HVEKDALYTSPETVFA 
                 189 
                 0.77 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 257 
                 266 
                 262 
                 KHPLYLVFHG 
               
               
                 80 
                 118 
                 103 
                 AASIAGSIAAAHYIRAIAPTYGIPVVLHTDHCAKKLLPW 
               
               
                 30 
                 49 
                 44 
                 FAIPAINVTSSSTVVAALEA 
               
               
                 280 
                 287 
                 285 
                 KNGVVKVN 
               
               
                 289 
                 303 
                 295 
                 DTDCQYAYLTGIRDY 
               
               
                 191 
                 239 
                 205 
                 EKDALYTSPETVFAVYESLHKISPNFSIAAAFGNVHGVYKPG 
               
               
                   
                   
                   
                 NVQLRPE 
               
               
                 4 
                 24 
                 5 
                 PAVLSKSGVIYGKDVKDLFDY 
               
               
                 305 
                 316 
                 313 
                 TNKIEYLKAPVG 
               
               
                 154 
                 160 
                 157 
                 IATCAKY 
               
               
                 241 
                 250 
                 244 
                 LGDHQVYAKK 
               
               
                 55 
                 61 
                 57 
                 APIILQT 
               
               
                 330 
                 336 
                 332 
                 DPRVWVR 
               
               
                 134 
                 144 
                 140 
                 GTPLFSSHMLD 
               
               
                 347 
                 353 
                 352 
                 AEALDIF 
               
               
                 65 
                 72 
                 71 
                 GAAYFAGK 
               
               
                   
               
            
           
           
               
               
            
               
                 64. IPF9162 
                   
               
               
                 MKKRLVLFDDSDDNSETESDKSKLKSRKKQFKIPEYPQPPSFPVNEQNEDYMKYQLQDDKHEEPTESAIDKK 
               
               
                   
               
               
                 DCSLFSNPSTSIGLSIMERMGFKIGNALGNSATAIKEPIEVSLKSGRQGLGGGFKPLQYKQEDVENLKLNLA 
               
               
                   
               
               
                 NSNKQRIELRDLKKIMKLCFELSGEYDKYLEGEDITEVNSLWQPYVKIYVSKQQSAAVGSVKAKFNAVETLQ 
               
               
                   
               
               
                 LFEREVENTEQTLSDLLNYLRGTHNYCWYCGLKYNDQNNLLANCPGKTRDIHLTI* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 PEYPQPPSFPVNEQNE 
                 34 
                 0.92 
               
               
                 1 
                 TESDKSKLKSRKKQFK 
                 17 
                 0.92 
               
               
                 2 
                 YLEGEDITEVNSLWQP 
                 173 
                 0.89 
               
               
                 3 
                 TESAIDKKDCSLFSNP 
                 65 
                 0.87 
               
               
                 3 
                 RGTHNYCWYCGLKYND 
                 237 
                 0.87 
               
               
                 3 
                 SGRQGLGGGFKPLQYK 
                 117 
                 0.87 
               
               
                 4 
                 GLSIMERMGFKIGNAL 
                 85 
                 0.84 
               
               
                 5 
                 TEVNSLWQPYVKIYVS 
                 180 
                 0.83 
               
               
                 6 
                 EVENTEQTLSDLLNYL 
                 221 
                 0.80 
               
               
                 6 
                 SGEYDKYLEGEDITEV 
                 167 
                 0.80 
               
               
                 7 
                 GFKIGNALGNSATAIK 
                 93 
                 0.78 
               
               
                 7 
                 ATAIKEPIEVSLKSGR 
                 104 
                 0.78 
               
               
                 8 
                 KRLVLFDDSDDNSETE 
                 3 
                 0.76 
               
               
                 8 
                 LLANCPGKTRDIHLTI 
                 256 
                 0.76 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 182 
                 220 
                 191 
                 VNSLWQPYVKIYVSKQQSAAVGSVKAKFNAVETLQLFER 
               
               
                 240 
                 249 
                 245 
                 HNYCWYCGLK 
               
               
                 159 
                 167 
                 164 
                 IMKLCFELS 
               
               
                 4 
                 9 
                 8 
                 RLVLFD 
               
               
                 31 
                 44 
                 41 
                 FKIPEYPQPPSFPV 
               
               
                 107 
                 116 
                 113 
                 IKEPIEVSLK 
               
               
                 71 
                 79 
                 77 
                 KKDCSLFSN 
               
               
                 229 
                 236 
                 232 
                 LSDLLNYL 
               
               
                 127 
                 134 
                 129 
                 KPLQYKQE 
               
               
                 53 
                 58 
                 54 
                 KYQLQD 
               
               
                 138 
                 143 
                 138 
                 NLKLNL 
               
               
                   
               
            
           
           
               
               
            
               
                 65. PGK1 
                   
               
               
                 MSLSNKLSVKDLDVAGKRVFIRVDFNVPLDGKTITNNQRIVAALPTIKYVEEHKPKYIVLASHLGRPNGERN 
               
               
                   
               
               
                 DKYSLAPVATELEKLLGQKVTFLNDCVGPEVTKAVENAKDGEIFLLENLRYHIEEEGSSKDKDGKKVKADPE 
               
               
                   
               
               
                 AVKKFRQELTSLADVYINDAFGTAHRAHSSMVGLEVPQRAAGFLMSKELEYFAKALENPERPFLAILGGAKV 
               
               
                   
               
               
                 SDKIQLIDNLLDKVDMLIVGGGMAFTFKKILNKMPIGDSLFDEAGAKNVEHLVEKAKKNNVELILPVDFVTA 
               
               
                   
               
               
                 DKFDKDAKTSSATDAEGIPDNWMGLDCGPKSVELFQQAVAKAKTIVWNGPPGVFEFEKFANGTKSLLDAAVK 
               
               
                   
               
               
                 SAENGNIVIIGGGDTATVAKKYGVVEKLSHVSTGGGASLELLEGKDLPGVVALSNKN* 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 DAEGIPDNWMGLDCGP 
                 302 
                 0.95 
               
               
                 2 
                 IVLASHLGRPNGERND 
                 58 
                 0.89 
               
               
                 2 
                 IVGGGMAFTFKKILNK 
                 234 
                 0.89 
               
               
                 2 
                 EGSSKDKDGKKVKADP 
                 128 
                 0.89 
               
               
                 3 
                 KMPIGDSLFDEAGAKN 
                 249 
                 0.88 
               
               
                 4 
                 DKDAKTSSATDAEGIP 
                 292 
                 0.86 
               
               
                 4 
                 PVDFVTADKFDKDAKT 
                 282 
                 0.86 
               
               
                 5 
                 GAKNVEHLVEKAKKNN 
                 261 
                 0.85 
               
               
                 6 
                 GGGDTATVAKKYGVVE 
                 371 
                 0.82 
               
               
                 6 
                 GFLMSKELEYFAKALE 
                 186 
                 0.82 
               
               
                 7 
                 GKTITNNQRIVAALPT 
                 31 
                 0.81 
               
               
                 7 
                 PERPFLAILGGAKVSD 
                 203 
                 0.81 
               
               
                 8 
                 AKTIVWNGPPGVFEFE 
                 330 
                 0.80 
               
               
                 9 
                 VGPEVTKAVENAKDGE 
                 99 
                 0.79 
               
               
                 9 
                 DAFGTAHRAHSSMVGL 
                 163 
                 0.79 
               
               
                 9 
                 GKRVFIRVDFNVPLDG 
                 16 
                 0.79 
               
               
                 9 
                 KFRQELTSLADVYIND 
                 148 
                 0.79 
               
               
                 10 
                 KADPEAVKKFRQELTS 
                 140 
                 0.77 
               
               
                 11 
                 NGERNDKYSLAPVATE 
                 68 
                 0.76 
               
               
                 11 
                 LELLEGKDLPGVVALS 
                 399 
                 0.76 
               
               
                 11 
                 KSLLDAAVKSAENGNI 
                 352 
                 0.76 
               
               
                 12 
                 KLSVKDLDVAGKRVFI 
                 6 
                 0.75 
               
               
                 12 
                 LPTIKYVEEHKPKYIV 
                 44 
                 0.75 
               
               
                 12 
                 PPGVFEFEKFANGTKS 
                 338 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 277 
                 289 
                 280 
                 VELILPVDFVTAD 
               
               
                 407 
                 414 
                 410 
                 LPGVVALS 
               
               
                 55 
                 64 
                 61 
                 PKYIVLASHL 
               
               
                 75 
                 106 
                 78 
                 YSLAPVATELEKLLGQKVTFLNDCVGPEVTKA 
               
               
                 376 
                 393 
                 387 
                 ATVAKKYGVVEKLSHVST 
               
               
                 352 
                 361 
                 356 
                 KSLLDAAVKS 
               
               
                 152 
                 162 
                 158 
                 ELTSLADVYIN 
               
               
                 39 
                 53 
                 43 
                 RIVAALPTIKYVEEH 
               
               
                 314 
                 333 
                 325 
                 DCGPKSVELFQQAVAKAKTI 
               
               
                 4 
                 31 
                 22 
                 SNKLSVKDLDVAGKRVFIRVDFNVPLDG 
               
               
                 173 
                 188 
                 179 
                 SSMVGLEVPQRAAGFL 
               
               
                 206 
                 237 
                 232 
                 PFLAILGGAKVSDKIQLIDNLLDKVDMLIVGG 
               
               
                 265 
                 271 
                 268 
                 VEHLVEK 
               
               
                 114 
                 124 
                 118 
                 EIFLLENLRYH 
               
               
                 339 
                 344 
                 341 
                 PGVFEF 
               
               
                 193 
                 199 
                 196 
                 LEYFAKA 
               
               
                 140 
                 149 
                 146 
                 KADPEAVKKF 
               
               
                   
               
            
           
           
               
               
            
               
                 66.  Aspergillus fumigatus  Afu2g10620 
                   
               
               
                 MSWKLTKKLKDTHLAPLTNTFTRSSSTSTIKNESGEETPVVSQTPSISSTNSNGINASESLVSPPVDPVKPG 
               
               
                   
               
               
                 ILIVTLHEGRGFALSPHFQQVFTSHFQNNNYSSSVRPSSSSSHSTHGQTASFAQSGRPQSTSGGINAAPTIH 
               
               
                   
               
               
                 GRYSTKYLPYALLDFEKNQVFVDAVSGTPENPLWAGDNTAFKFDVSRKTELNVQLYLRNPSARPGAGRSEDI 
               
               
                   
               
               
                 FLGAVRVLPRFEEAQPYVDDPKLSKKDNQKAAAAHANNERHLGQLGAEWLDLQFGTGSIKIGVSFVENKQRS 
               
               
                   
               
               
                 LKLEDFDLLKVVGKGSFGKVMQVMKKDTGRIYALKTIRKAHIISRSEVTHTLAERSVLAQINNPFIVPLKFS 
               
               
                   
               
               
                 FQSPEKLYLVLAFVNGGELFHHLQREQRFDINRARFYTAELLCALECLHGFKVIYRDLKPENILLDYTGHIA 
               
               
                   
               
               
                 LCDFGLCKLDMKDEDRTNTFCGTPEYLAPELLLGNGYTKTVDWWTLGVLLYEMLTGLPPFYDENTNDMYRKI 
               
               
                   
               
               
                 LQEPLTFPSSDIVPPAARDLLTRLLDRDPQRRLGANGAAEIKSHHFFANIDWRKLLQRKYEPSFRPNVMGAS 
               
               
                   
               
               
                 DTTNFDTEFTSEAPQDSYVDGPVLSQTMQQQFAGWSYNRPVAGLGDAGGSVKDPSFGSIPE 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 YEPSFRPNVMGASDTT 
                 564 
                 0.95 
               
               
                 2 
                 EMLTGLPPFYDENTND 
                 484 
                 0.93 
               
               
                 2 
                 HGRYSTKYLPYALLDF 
                 144 
                 0.93 
               
               
                 2 
                 SGGINAAPTIHGRYST 
                 134 
                 0.93 
               
               
                 3 
                 TPSISSTNSNGINASE 
                 44 
                 0.91 
               
               
                 4 
                 SEAPQDSYVDGPVLSQ 
                 587 
                 0.88 
               
               
                 4 
                 TGSIKIGVSFVENKQR 
                 272 
                 0.88 
               
               
                 4 
                 AQPYVDDPKLSKKDNQ 
                 230 
                 0.88 
               
               
                 5 
                 QFAGWSYNRPVAGLGD 
                 607 
                 0.87 
               
               
                 5 
                 LDMKDEDRTNTFCGTP 
                 441 
                 0.87 
               
               
                 6 
                 TRLLDRDPQRRLGANG 
                 526 
                 0.86 
               
               
                 6 
                 AVSGTPENPLWAGDNT 
                 168 
                 0.86 
               
               
                 7 
                 FKVIYRDLKPENILLD 
                 411 
                 0.85 
               
               
                 8 
                 RPVAGLGDAGGSVKDP 
                 615 
                 0.84 
               
               
                 8 
                 PPAARDLLTRLLDRDP 
                 518 
                 0.84 
               
               
                 8 
                 QVMKKDTGRIYALKTI 
                 310 
                 0.84 
               
               
                 8 
                 PSSSSSHSTHGQTASF 
                 109 
                 0.84 
               
               
                 9 
                 VMGASDTTNFDTEFTS 
                 572 
                 0.83 
               
               
                 9 
                 RKILQEPLTFPSSDIV 
                 502 
                 0.83 
               
               
                 9 
                 KYLPYALLDFEKNQVF 
                 150 
                 0.83 
               
               
                 10 
                 RKLLQRKYEPSFRPNV 
                 557 
                 0.82 
               
               
                 10 
                 AAEIKSHHFFANIDWR 
                 542 
                 0.82 
               
               
                 10 
                 GGELFHHLQREQRFDI 
                 376 
                 0.82 
               
               
                 10 
                 RSEVTHTLAERSVLAQ 
                 333 
                 0.82 
               
               
                 11 
                 DRTNTFCGTPEYLAPE 
                 447 
                 0.81 
               
               
                 11 
                 TGHIALCDFGLCKLDM 
                 428 
                 0.81 
               
               
                 11 
                 RFDINRARFYTAELLC 
                 388 
                 0.81 
               
               
                 11 
                 GQTASFAQSGRPQSTS 
                 119 
                 0.81 
               
               
                 12 
                 KAHIISRSEVTHTLAE 
                 327 
                 0.80 
               
               
                 12 
                 TGRIYALKTIRKAHII 
                 316 
                 0.80 
               
               
                 12 
                 IKNESGEETPVVSQTP 
                 30 
                 0.80 
               
               
                 12 
                 NPLWAGDNTAFKFDVS 
                 175 
                 0.80 
               
               
                 13 
                 VSPPVDPVKPGILIVT 
                 62 
                 0.79 
               
               
                 13 
                 PENILLDYTGHIALCD 
                 420 
                 0.79 
               
               
                 13 
                 KLTKKLKDTHLAPLTN 
                 4 
                 0.79 
               
               
                 13 
                 THLAPLTNTFTRSSST 
                 12 
                 0.79 
               
               
                 14 
                 SGRPQSTSGGINAAPT 
                 127 
                 0.78 
               
               
                 15 
                 VGKGSFGKVMQVMKKD 
                 300 
                 0.76 
               
               
                 15 
                 LGAEWLDLQFGTGSIK 
                 261 
                 0.76 
               
               
                 15 
                 VSRKTELNVQLYLRNP 
                 189 
                 0.76 
               
               
                 16 
                 GILIVTLHEGRGFALS 
                 72 
                 0.75 
               
               
                 16 
                 FYDENTNDMYRKILQE 
                 492 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 364 
                 374 
                 371 
                 PEKLYLVLAFV 
               
               
                 396 
                 417 
                 404 
                 FYTAELLCALECLHGFKVIYRD 
               
               
                 58 
                 79 
                 76 
                 SESLVSPPVDPVKPGILIVTLH 
               
               
                 149 
                 159 
                 154 
                 TKYLPYALLDF 
               
               
                 162 
                 171 
                 166 
                 NQVFVDAVSG 
               
               
                 421 
                 442 
                 436 
                 ENILLDYTGHIALCDFGLCKLD 
               
               
                 288 
                 303 
                 297 
                 SLKLEDFDLLKVVGKG 
               
               
                 195 
                 203 
                 198 
                 LNVQLYLRN 
               
               
                 475 
                 492 
                 480 
                 WWTLGVLLYEMLTGLPPF 
               
               
                 215 
                 227 
                 221 
                 DIFLGAVRVLPRF 
               
               
                 591 
                 603 
                 597 
                 QDSYVDGPVLSQT 
               
               
                 453 
                 467 
                 462 
                 CGTPEYLAPELLLGN 
               
               
                 351 
                 362 
                 356 
                 NPFIVPLKFSFQ 
               
               
                 38 
                 47 
                 42 
                 TPVVSQTPSI 
               
               
                 276 
                 283 
                 279 
                 KIGVSFVE 
               
               
                 84 
                 96 
                 91 
                 FALSPHFQQVFTS 
               
               
                 341 
                 349 
                 346 
                 AERSVLAQI 
               
               
                 379 
                 384 
                 382 
                 LFHHLQ 
               
               
                 502 
                 528 
                 519 
                 RKILQEPLTFPSSDIVPPAARDLLTRL 
               
               
                 319 
                 325 
                 322 
                 IYALKTI 
               
               
                 11 
                 18 
                 15 
                 DTHLAPLT 
               
               
                 230 
                 237 
                 236 
                 AQPYVDDP 
               
               
                 104 
                 110 
                 106 
                 SSSVRPS 
               
               
                 545 
                 552 
                 548 
                 IKSHHFFA 
               
               
                 327 
                 339 
                 338 
                 KAHIISRSEVTHT 
               
               
                 557 
                 563 
                 561 
                 RKLLQRK 
               
               
                 614 
                 620 
                 618 
                 NRPVAGL 
               
               
                 625 
                 630 
                 629 
                 GSVKDP 
               
               
                 263 
                 269 
                 269 
                 AEWLDLQ 
               
               
                 140 
                 146 
                 142 
                 APTIHGR 
               
               
                 112 
                 117 
                 112 
                 SSSHST 
               
               
                   
               
            
           
           
               
               
            
               
                 67.  Aspergillus nidulans  AN8970.2 
                   
               
               
                 MTIFRRVALIGRGSLGTVLLDELLNSNFTVTVLTRSASSASSLPPGADIKQVDYSSAESLKTALAGHDIVIS 
               
               
                   
               
               
                 TLSPSAIPLQKQVIDAAIAVGVKRFIPAEYGAMTSDPVGRKLPFHKDAIEIHEFLRETVASGLIEYTVFGVG 
               
               
                   
               
               
                 VLTELLFTTTLVVDLEHREVKLFDGGIHSFSTSRLETVARAVVASLHKPDETRNRVIRVHDAVLTQRQVLDM 
               
               
                   
               
               
                 AKGWTPTLEWREVYVDAQAEVDRGLKQLEKEFSPALVPGVFAAALMSGRYGAEYKEVDNELLGLGFMDKREI 
               
               
                   
               
               
                 NDFGKKFTK 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 ASGLIEYTVFGVGVLT 
                 132 
                 0.93 
               
               
                 2 
                 VALIGRGSLGTVLLDE 
                 7 
                 0.87 
               
               
                 2 
                 EVYVDAQAEVDRGLKQ 
                 228 
                 0.87 
               
               
                 3 
                 FMDKREINDFGKKFTK 
                 282 
                 0.86 
               
               
                 3 
                 LMSGRYGAEYKEVDNE 
                 261 
                 0.86 
               
               
                 3 
                 VLTQRQVLDMAKGWTP 
                 207 
                 0.86 
               
               
                 4 
                 AEYGAMTSDPVGRKLP 
                 100 
                 0.84 
               
               
                 5 
                 RGLKQLEKEFSPALVP 
                 239 
                 0.83 
               
               
                 5 
                 HSFSTSRLETVARAVV 
                 172 
                 0.83 
               
               
                 6 
                 TVTVLTRSASSASSLP 
                 29 
                 0.82 
               
               
                 7 
                 GVKRFIPAEYGAMTSD 
                 93 
                 0.81 
               
               
                 7 
                 KQVIDAAIAVGVKRFI 
                 83 
                 0.81 
               
               
                 8 
                 SSASSLPPGADIKQVD 
                 38 
                 0.80 
               
               
                 9 
                 MAKGWTPTLEWREVYV 
                 216 
                 0.79 
               
               
                 10 
                 HDIVISTLSPSAIPLQ 
                 67 
                 0.76 
               
               
                 11 
                 ETRNRVIRVHDAVLTQ 
                 195 
                 0.75 
               
               
                 11 
                 TVLLDELLNSNFTVTV 
                 17 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 179 
                 192 
                 188 
                 LETVARAVVASLHK 
               
               
                 132 
                 169 
                 143 
                 ASGLIEYTVFGVGVLTELLFTTTLVVDLE 
               
               
                   
                   
                   
                 HREVKLFDG 
               
               
                 249 
                 261 
                 254 
                 SPALVPGVFAAAL 
               
               
                 15 
                 23 
                 21 
                 LGTVLLDEL 
               
               
                 57 
                 101 
                 91 
                 AESLKTALAGHDIVISTLSPSAIPLQ 
               
               
                   
                   
                   
                 KQVIDAAIAVGVKRFIPAE 
               
               
                 200 
                 216 
                 206 
                 VIRVHDAVLTQRQVLDM 
               
               
                 226 
                 236 
                 232 
                 WREVYVDAQAE 
               
               
                 29 
                 36 
                 31 
                 TVTVLTRS 
               
               
                 4 
                 12 
                 6 
                 FRRVALIGR 
               
               
                 49 
                 55 
                 52 
                 IKQVDYS 
               
               
                 38 
                 47 
                 42 
                 SSASSLPPGA 
               
               
                 110 
                 126 
                 113 
                 VGRKLPFHKDAIEIHEF 
               
               
                 275 
                 281 
                 279 
                 NELLGLG 
               
               
                 238 
                 244 
                 240 
                 DRGLKQL 
               
               
                   
               
            
           
           
               
               
            
               
                 68.  Aspergillus nidulans  AN2162.2 
                   
               
               
                 MDQAIYISSSSEDGFNDDPPLFDEGDNFQEQLPDEERFAAYFDRETPEELFPDRFPKRQRIHGPGDVALDQM 
               
               
                   
               
               
                 LSSPLAFRGPDSPQSSMAAAADGANTLFLQILEIFPGISHTYVNDLIAQKTVAFRLGADLKARGFQLAILRD 
               
               
                   
               
               
                 SIYEEILGQKSYPKQDSENGKRKREESEEADISWERTLQNATNSPEYFEAASAFLGPEFPWVPMSHIKKVLI 
               
               
                   
               
               
                 DKGRLYHAFVALYSDDNLLEQRKYQYVRLKSQRSTNSPKKYTPLRDTLIREINAARKHVEELQITLRKKKEE 
               
               
                   
               
               
                 EEAEKANEEEHIRTGSLIECHCCYADVPSNRCIPCDGDDLHFFCFTCIRRSADNQIGMMKYILQCFDVSGCQ 
               
               
                   
               
               
                 ASFNRQQLREILGPVVMDKLDSLQQEDEIRKAGLEGLEDCPFCSYKAVLPPVEEDREFRCENSQCKVVSCRL 
               
               
                   
               
               
                 CKEKSHIPQTCEEYRKDKGLSERHQVEEAMSNALIRKCPKCRLKIIKEYGCNKMQCTKCHTLMCYVCQKDIT 
               
               
                   
               
               
                 KEGYAHFGRGGCPQDDIHTQDRDDREIQRAERAAIDKILAENPDISEEQIRVGHEKTNAQTRGVRRDPRLQP 
               
               
                   
               
               
                 AIQMRDAMRVMRADMGGFYPQQHQHANTAAQRQLPVYPPPAYNVPYPMDYGTMFNPPFPGFNVLQRGLQPGN 
               
               
                   
               
               
                 LPAQPAVMQPMVVGLANPPANFHPQDIQNITAFPPQQSLPRNQNAAYRGVGFGPF 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 DGFNDDPPLFDEGDNF 
                 13 
                 0.97 
               
               
                 2 
                 LREILGPVVMDKLDSL 
                 368 
                 0.95 
               
               
                 3 
                 GHEKTNAQTRGVRRDP 
                 557 
                 0.94 
               
               
                 4 
                 DQMLSSPLAFRGPDSP 
                 70 
                 0.93 
               
               
                 4 
                 AIYISSSSEDGFNDDP 
                 4 
                 0.93 
               
               
                 4 
                 ECHCCYADVPSNRCIP 
                 307 
                 0.93 
               
               
                 5 
                 YGTMFNPPFPGFNVLQ 
                 626 
                 0.91 
               
               
                 5 
                 KVLIDKGRLYHAFVAL 
                 213 
                 0.91 
               
               
                 6 
                 DITKEGYAHFGRGGCP 
                 502 
                 0.90 
               
               
                 6 
                 EDEIRKAGLEGLEDCP 
                 386 
                 0.90 
               
               
                 7 
                 IREINAARKHVEELQI 
                 265 
                 0.89 
               
               
                 7 
                 FPGISHTYVNDLIAQK 
                 107 
                 0.89 
               
               
                 8 
                 RQLPVYPPPAYNVPYP 
                 608 
                 0.88 
               
               
                 8 
                 FGRGGCPQDDIHTQDR 
                 511 
                 0.88 
               
               
                 9 
                 FRGPDSPQSSMAAAAD 
                 79 
                 0.87 
               
               
                 9 
                 ADMGGFYPQQHQHANT 
                 589 
                 0.87 
               
               
                 9 
                 QPAIQMRDAMRVMRAD 
                 575 
                 0.87 
               
               
                 10 
                 AYNVPYPMDYGTMFNP 
                 617 
                 0.86 
               
               
                 10 
                 KGLSERHQVEEAMSNA 
                 450 
                 0.86 
               
               
                 10 
                 YFDRETPEELFPDRFP 
                 41 
                 0.86 
               
               
                 10 
                 GMMKYILQCFDVSGCQ 
                 345 
                 0.86 
               
               
                 11 
                 RLKIIKEYGCNKMQCT 
                 474 
                 0.85 
               
               
                 12 
                 PDISEEQIRVGHEKTN 
                 547 
                 0.84 
               
               
                 12 
                 MQCTKCHTLMCYVCQK 
                 486 
                 0.84 
               
               
                 12 
                 SHIPQTCEEYRKDKGL 
                 437 
                 0.84 
               
               
                 12 
                 LPPVEEDREFRCENSQ 
                 409 
                 0.84 
               
               
                 13 
                 QDDIHTQDRDDREIQR 
                 518 
                 0.83 
               
               
                 13 
                 DLIAQKTVAFRLGADL 
                 117 
                 0.83 
               
               
                 14 
                 RRSADNQIGMMKYILQ 
                 337 
                 0.82 
               
               
                 15 
                 NALIRKCPKCRLKIIK 
                 464 
                 0.81 
               
               
                 15 
                 LKSQRSTNSPKKYTPL 
                 245 
                 0.81 
               
               
                 15 
                 PEFPWVPMSHIKKVLI 
                 201 
                 0.81 
               
               
                 16 
                 NITAFPPQQSLPRNQN 
                 677 
                 0.80 
               
               
                 16 
                 CYVCQKDITKEGYAHF 
                 496 
                 0.80 
               
               
                 16 
                 EGLEDCPFCSYKAVLP 
                 395 
                 0.80 
               
               
                 16 
                 RDSIYEEILGQKSYPK 
                 143 
                 0.80 
               
               
                 17 
                 NVLQRGLQPGNLPAQP 
                 638 
                 0.79 
               
               
                 17 
                 EEEAEKANEEEHIRTG 
                 288 
                 0.79 
               
               
                 17 
                 TNSPEYFEAASAFLGP 
                 186 
                 0.79 
               
               
                 17 
                 ADISWERTLQNATNSP 
                 174 
                 0.79 
               
               
                 18 
                 AQPAVMQPMVVGLANP 
                 651 
                 0.78 
               
               
                 18 
                 HQHANTAAQRQLPVYP 
                 599 
                 0.78 
               
               
                 18 
                 RQRIHGPGDVALDQML 
                 58 
                 0.78 
               
               
                 19 
                 PDEERFAAYFDRETPE 
                 33 
                 0.77 
               
               
                 19 
                 FEAASAFLGPEFPWVP 
                 192 
                 0.77 
               
               
                 20 
                 HQVEEAMSNALIRKCP 
                 456 
                 0.76 
               
               
                 20 
                 RCIPCDGDDLHFFCFT 
                 319 
                 0.76 
               
               
                 20 
                 QKSYPKQDSENGKRKR 
                 153 
                 0.76 
               
               
                 21 
                 LQPGNLPAQPAVMQPM 
                 644 
                 0.75 
               
               
                 21 
                 RAAIDKILAENPDISE 
                 536 
                 0.75 
               
               
                 21 
                 NFQEQLPDEERFAAYF 
                 27 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 421 
                 444 
                 430 
                 ENSQCKVVSCRLCKEKSHIPQTCE 
               
               
                 305 
                 326 
                 308 
                 LIECHCCYADVPSNRCIPCDGD 
               
               
                 488 
                 502 
                 497 
                 CTKCHTLMCYVCQKD 
               
               
                 397 
                 412 
                 406 
                 LEDCPFCSYKAVLPPV 
               
               
                 348 
                 362 
                 353 
                 KYILQCFDVSGCQAS 
               
               
                 328 
                 338 
                 333 
                 LHFFCFTCIRR 
               
               
                 191 
                 229 
                 224 
                 YFEAASAFLGPEFPWVPMSHIKKVLIDKGRLYHAFVALY 
               
               
                 607 
                 624 
                 613 
                 QRQLPVYPPPAYNVPYPM 
               
               
                 368 
                 383 
                 373 
                 LREILGPVVMDKLDSL 
               
               
                 98 
                 131 
                 101 
                 TLFLQILEIFPGISHTYVNDLIAQKTVAFRLGAD 
               
               
                 646 
                 666 
                 652 
                 PGNLPAQPAVMQPMVVGLANP 
               
               
                 466 
                 481 
                 472 
                 LIRKCPKCRLKIIKEY 
               
               
                 237 
                 246 
                 242 
                 QRKYQYVRLK 
               
               
                 64 
                 80 
                 76 
                 PGDVALDQMLSSPLAFR 
               
               
                 135 
                 145 
                 139 
                 RGFQLAILRDS 
               
               
                 633 
                 643 
                 642 
                 PFPGFNVLQRG 
               
               
                 272 
                 282 
                 277 
                 RKHVEELQITL 
               
               
                 4 
                 9 
                 6 
                 AIYISS 
               
               
                 678 
                 688 
                 684 
                 ITAFPPQQSLP 
               
               
                 573 
                 578 
                 575 
                 RLQPAI 
               
               
                 595 
                 600 
                 598 
                 YPQQHQ 
               
               
                 256 
                 263 
                 262 
                 KYTPLRDT 
               
               
                 695 
                 700 
                 697 
                 YRGVGF 
               
               
                   
               
            
           
           
               
               
            
               
                 69.  Aspergillus nidulans  AN6709.2 
                   
               
               
                 MAEAENDPTNELNQTSVTQADKQNGVDVATEPHAPEVVAESKPALTDESERQEIPTIKENEDTMANNRLNDS 
               
               
                   
               
               
                 KNNLPHEPSVTSPDTTTDSNEPTDEPEQPHTEGDQLETLQQDQPPASDEQLNEAPDAPSTRDEQLAQDMRQR 
               
               
                   
               
               
                 SDSRSTTATFATNRSSVVSSTVFIVTALDAIGASREARKSKELEDAVKNALANVKQSDRQPIDPEILFYPLL 
               
               
                   
               
               
                 LASRTLSIPLQVTALDCIGKLITYSYFAFPSAQEAKPSEADATAEQPPLIERAIDAICDCFENEATPIEIQQ 
               
               
                   
               
               
                 QIIKSLLAAVLNDKIVVHGAGLLKAVRQIYNMFIYSKSSQNQQIAQGSLTQMVSTVFDRLRVRLDLRELRIR 
               
               
                   
               
               
                 EGEKAQAGSSESVTIEPVVSPPSAEDDQASDVASVAADQPVSKEPTEKLTLESFESNKDVTTVNDNVPTMVT 
               
               
                   
               
               
                 RANINQKRTQSYSGTSSEEKEAEDASSNEDDVDEIYVKDAFLVFRALCKLSHKVLSHEQQQDLKSQNMRSKL 
               
               
                   
               
               
                 LSLHLIHYLINNHVIIFTTPLLTLKNSSGNLEAMTFLQAIRPHLCLSLSRNGASSVPKVFEVCCEIFWLMLK 
               
               
                   
               
               
                 HMRVMMKKELEVFMKEIYLAILEKRNAPAFQKQYFMEILERLADEPRALVEMYLNYDCDRTALENIFQNIIE 
               
               
                   
               
               
                 QLSRYASIPTVVNPLQQQQYHELHVKASSVGNEWHQRGTLPPNLTSASIGNNQQPPTHSVPSEYILKHQAVE 
               
               
                   
               
               
                 CLVVILESLDNWASQRSVDPTAARTFSQKSVDNPRDSMDSSAPAFLASPRVDGADGSTGRSTPVPDDDPSQV 
               
               
                   
               
               
                 EKVKQRKIALTNVIQQFNFKPKRGVKLALQEGFIRSDSPEDIAAFILRNDRLDKAMIGEYLGEGDAENIATM 
               
               
                   
               
               
                 HAFVDMMDFSKRRFVDALRSFLQHFRLPGEAQKIDRFMLKFSERYVTQNPNAFANADTAYVLAYSVILLNTD 
               
               
                   
               
               
                 QHSSKMKGRRMTKEDFIKNNRGINDNQDLPDEYLGSIFDEIANNEIVLDTEREQAANAAHPAPVPSGLASRA 
               
               
                   
               
               
                 GQVFATVGRDIQGERYAQASEEMANKTEQLYRSLIRAQRKTAVKEALSRFIFATSVQHAGSMFNVTWMSFLS 
               
               
                   
               
               
                 GLSAPMQDTQNLKTIKLCMEGMKLAIRISCTFDLETPRVAFVTALAKFTNLGNVREMVAKNVEAVKILLDVA 
               
               
                   
               
               
                 LSEGNHLKSSWRDILTCVSQLDRLQLLSDGVDEGSLPDMSRAGVVPPSASDGPRRSMQAPRRPRPKSITGPT 
               
               
                   
               
               
                 PFRAEIAMESRSTEMVKGVDRIFTNTANLSHEAIIDFVRALSEVSWQEIQSSGQTASPRTYSLQKLVEISYY 
               
               
                   
               
               
                 NMTRVRIEWSKIWEVLGQHFNQVGCHSNTTVVFFALDSLRQLSMRFMEIEELPGFKFQKDFLKPFEHVMSNS 
               
               
                   
               
               
                 NAVTVKDMILRCLIQMIQARGDNIRSGWKTMFGVFSFAAREPYDTEGIVNMAFEHVTQIYNTRFGVVITQGA 
               
               
                   
               
               
                 FPDLVVCLTEFSKNTRFQKKSLQAIELLKSTVAKMLRTPECPLSHRSSTEAFHEDSTNLTQQLTKQSKEEQF 
               
               
                   
               
               
                 WYPILIAFQDILMTGDDLEARSRALTYLFDTLIRYGGSFPQEFWDVLWRQLLYPIFVVLQSKSEMSKVPNHE 
               
               
                   
               
               
                 ELSVWLSTTMIQALRHMITLFTHYFDALEYMLGRVLELLTLCICQENDTIARIGSNCLQQLILQNVEKFQKD 
               
               
                   
               
               
                 HWNKTVGAFIELFNKTTAYELFTAATTMATVTLKTPSAPTANGQLADTHDTVQDPTESSPAQETSTEPPKLN 
               
               
                   
               
               
                 GTQDTTAEHEDGDMPAASNTELEDYRPQSDTQQQPAAVTAARRRYFNRIITSCVLQLLMIETVHELFSNDKV 
               
               
                   
               
               
                 YAQIPSHELLRLMGLLKKSYQFAKKFNEDKELRMQLWRQGFMKSPPNLLKQESGSAATYVHILFRMYHDERE 
               
               
                   
               
               
                 ERKSSRSETEAALIPLCVDIISGFVRLDEDSQHRNIVAWRPVVVDVIEGYTNFPAEGFDKHIDTFYPLAVDL 
               
               
                   
               
               
                 LGRELNSEIRLAIQGLFQRIGEARLGLPVRPTPTPVSPRHSVSEHPSRKHSVGRR 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 PKSITGPTPFRAEIAM 
                 1217 
                 0.96 
               
               
                 2 
                 TELEDYRPQSDTQQQP 
                 1748 
                 0.94 
               
               
                 2 
                 NEAPDAPSTRDEQLAQ 
                 124 
                 0.94 
               
               
                 2 
                 RRSMQAPRRPRPKSIT 
                 1206 
                 0.94 
               
               
                 3 
                 TANGQLADTHDTVQDP 
                 1696 
                 0.93 
               
               
                 4 
                 LGSIFDEIANNEIVLD 
                 970 
                 0.91 
               
               
                 4 
                 SVTSPDTTTDSNEPTD 
                 81 
                 0.91 
               
               
                 4 
                 VDEGSLPDMSRAGVVP 
                 1183 
                 0.91 
               
               
                 4 
                 TLQQDQPPASDEQLNE 
                 110 
                 0.91 
               
               
                 5 
                 HSSKMKGRRMTKEDFI 
                 938 
                 0.90 
               
               
                 5 
                 NWASQRSVDPTAARTF 
                 731 
                 0.90 
               
               
                 5 
                 HEDGDMPAASNTELED 
                 1737 
                 0.90 
               
               
                 5 
                 TRDEQLAQDMRQRSDS 
                 132 
                 0.90 
               
               
                 6 
                 RMTKEDFIKNNRGIND 
                 946 
                 0.89 
               
               
                 6 
                 PGEAQKIDRFMLKFSE 
                 892 
                 0.89 
               
               
                 6 
                 GSTGRSTPVPDDDPSQ 
                 776 
                 0.89 
               
               
                 6 
                 TIKENEDTMANNRLND 
                 56 
                 0.89 
               
               
                 6 
                 TPTPVSPRHSVSEHPS 
                 1976 
                 0.89 
               
               
                 7 
                 SPRVDGADGSTGRSTP 
                 768 
                 0.88 
               
               
                 7 
                 AVLNDKIVVHGAGLLK 
                 297 
                 0.88 
               
               
                 7 
                 ERAIDAICDCFENEAT 
                 267 
                 0.88 
               
               
                 7 
                 NGTQDTTAEHEDGDMP 
                 1728 
                 0.88 
               
               
                 7 
                 SPAQETSTEPPKLNGT 
                 1715 
                 0.88 
               
               
                 7 
                 HDTVQDPTESSPAQET 
                 1705 
                 0.88 
               
               
                 7 
                 LKTPSAPTANGQLADT 
                 1689 
                 0.88 
               
               
                 7 
                 GVVITQGAFPDLVVCL 
                 1433 
                 0.88 
               
               
                 8 
                 RGINDNQDLPDEYLGS 
                 957 
                 0.87 
               
               
                 8 
                 QKSVDNPRDSMDSSAP 
                 748 
                 0.87 
               
               
                 8 
                 EILERLADEPRALVEM 
                 613 
                 0.87 
               
               
                 8 
                 IYVKDAFLVFRALCKL 
                 467 
                 0.87 
               
               
                 8 
                 TTVNDNVPTMVTRANI 
                 421 
                 0.87 
               
               
                 8 
                 AYELFTAATTMATVTL 
                 1674 
                 0.87 
               
               
                 8 
                 HVTQIYNTRFGVVITQ 
                 1423 
                 0.87 
               
               
                 8 
                 AREPYDTEGIVNMAFE 
                 1407 
                 0.87 
               
               
                 8 
                 KSSWRDILTCVSQLDR 
                 1160 
                 0.87 
               
               
                 8 
                 KLAIRISCTFDLETPR 
                 1103 
                 0.87 
               
               
                 9 
                 DEPEQPHTEGDQLETL 
                 96 
                 0.86 
               
               
                 9 
                 SVDPTAARTFSQKSVD 
                 737 
                 0.86 
               
               
                 9 
                 RALVEMYLNYDCDRTA 
                 623 
                 0.86 
               
               
                 9 
                 VATEPHAPEVVAESKP 
                 28 
                 0.86 
               
               
                 9 
                 AVTAARRRYFNRIITS 
                 1765 
                 0.86 
               
               
                 9 
                 FTHYFDALEYMLGRVL 
                 1605 
                 0.86 
               
               
                 10 
                 EGFIRSDSPEDIAAFI 
                 823 
                 0.85 
               
               
                 10 
                 TPVPDDDPSQVEKVKQ 
                 782 
                 0.85 
               
               
                 10 
                 SHEQQQDLKSQNMRSK 
                 488 
                 0.85 
               
               
                 10 
                 SLTQMVSTVFDRLRVR 
                 336 
                 0.85 
               
               
                 10 
                 VDVIEGYTNFPAEGFD 
                 1916 
                 0.85 
               
               
                 10 
                 MGLLKKSYQFAKKFNE 
                 1813 
                 0.85 
               
               
                 10 
                 REARKSKELEDAVKNA 
                 179 
                 0.85 
               
               
                 10 
                 LDAIGASREARKSKEL 
                 172 
                 0.85 
               
               
                 10 
                 AKMLRTPECPLSHRSS 
                 1473 
                 0.85 
               
               
                 10 
                 QSSGQTASPRTYSLQK 
                 1274 
                 0.85 
               
               
                 10 
                 EVSWQEIQSSGQTASP 
                 1267 
                 0.85 
               
               
                 11 
                 PAPVPSGLASRAGQVF 
                 997 
                 0.84 
               
               
                 11 
                 DPSQVEKVKQRKIALT 
                 788 
                 0.84 
               
               
                 11 
                 TQSYSGTSSEEKEAED 
                 441 
                 0.84 
               
               
                 11 
                 DVASVAADQPVSKEPT 
                 391 
                 0.84 
               
               
                 11 
                 IGEARLGLPVRPTPTP 
                 1964 
                 0.84 
               
               
                 11 
                 EVLGQHFNQVGCHSNT 
                 1310 
                 0.84 
               
               
                 11 
                 IAMESRSTEMVKGVDR 
                 1230 
                 0.84 
               
               
                 11 
                 APMQDTQNLKTIKLCM 
                 1084 
                 0.84 
               
               
                 12 
                 FSERYVTQNPNAFANA 
                 905 
                 0.83 
               
               
                 12 
                 EKLTLESFESNKDVTT 
                 407 
                 0.83 
               
               
                 12 
                 ATAEQPPLIERAIDAI 
                 258 
                 0.83 
               
               
                 12 
                 FPSAQEAKPSEADATA 
                 245 
                 0.83 
               
               
                 12 
                 TTMIQALRHMITLFTH 
                 1592 
                 0.83 
               
               
                 12 
                 LSHRSSTEAFHEDSTN 
                 1483 
                 0.83 
               
               
                 12 
                 SDSRSTTATFATNRSS 
                 145 
                 0.83 
               
               
                 12 
                 FMEIEELPGFKFQKDF 
                 1342 
                 0.83 
               
               
                 12 
                 HEAIIDFVRALSEVSW 
                 1255 
                 0.83 
               
               
                 13 
                 PRDSMDSSAPAFLASP 
                 754 
                 0.82 
               
               
                 13 
                 EDDVDEIYVKDAFLVF 
                 461 
                 0.82 
               
               
                 13 
                 ELRIREGEKAQAGSSE 
                 356 
                 0.82 
               
               
                 13 
                 GKLITYSYFAFPSAQE 
                 235 
                 0.82 
               
               
                 13 
                 IQMIQARGDNIRSGWK 
                 1382 
                 0.82 
               
               
                 13 
                 ASDEQLNEAPDAPSTR 
                 118 
                 0.82 
               
               
                 13 
                 LKTIKLCMEGMKLAIR 
                 1092 
                 0.82 
               
               
                 13 
                 ERYAQASEEMANKTEQ 
                 1022 
                 0.82 
               
               
                 14 
                 ASSVGNEWHQRGTLPP 
                 675 
                 0.81 
               
               
                 14 
                 SEEKEAEDASSNEDDV 
                 449 
                 0.81 
               
               
                 14 
                 SFESNKDVTTVNDNVP 
                 413 
                 0.81 
               
               
                 14 
                 EPVVSPPSAEDDQASD 
                 376 
                 0.81 
               
               
                 14 
                 HILFRMYHDEREERKS 
                 1861 
                 0.81 
               
               
                 14 
                 GCHSNTTVVFFALDSL 
                 1320 
                 0.81 
               
               
                 14 
                 IFTNTANLSHEAIIDF 
                 1246 
                 0.81 
               
               
                 14 
                 VPPSASDGPRRSMQAP 
                 1197 
                 0.81 
               
               
                 15 
                 TDSNEPTDEPEQPHTE 
                 89 
                 0.80 
               
               
                 15 
                 EGFDKHIDTFYPLAVD 
                 1928 
                 0.80 
               
               
                 15 
                 RSSVVSSTVFIVTALD 
                 158 
                 0.80 
               
               
                 15 
                 FVVLQSKSEMSKVPNH 
                 1568 
                 0.80 
               
               
                 16 
                 DRFMLKFSERYVTQNP 
                 899 
                 0.79 
               
               
                 16 
                 PPTHSVPSEYILKHQA 
                 703 
                 0.79 
               
               
                 16 
                 SRYASIPTVVNPLQQQ 
                 651 
                 0.79 
               
               
                 16 
                 KPALTDESERQEIPTI 
                 42 
                 0.79 
               
               
                 16 
                 GIVNMAFEHVTQIYNT 
                 1415 
                 0.79 
               
               
                 16 
                 LVEISYYNMTRVRIEW 
                 1290 
                 0.79 
               
               
                 16 
                 SRFIFATSVQHAGSMF 
                 1056 
                 0.79 
               
               
                 16 
                 NELNQTSVTQADKQNG 
                 10 
                 0.79 
               
               
                 17 
                 NNEIVLDTEREQAANA 
                 979 
                 0.78 
               
               
                 17 
                 KAMIGEYLGEGDAENI 
                 846 
                 0.78 
               
               
                 17 
                 EWHQRGTLPPNLTSAS 
                 681 
                 0.78 
               
               
                 17 
                 VMMKKELEVFMKEIYL 
                 580 
                 0.78 
               
               
                 17 
                 HVIIFTTPLLTLKNSS 
                 517 
                 0.78 
               
               
                 17 
                 DPEILFYPLLLASRTL 
                 207 
                 0.78 
               
               
                 17 
                 AATTMATVTLKTPSAP 
                 1680 
                 0.78 
               
               
                 17 
                 DVLWRQLLYPIFVVLQ 
                 1557 
                 0.78 
               
               
                 17 
                 ILMTGDDLEARSRALT 
                 1523 
                 0.78 
               
               
                 17 
                 GWKTMFGVFSFAAREP 
                 1395 
                 0.78 
               
               
                 17 
                 TVGRDIQGERYAQASE 
                 1014 
                 0.78 
               
               
                 18 
                 PEDIAAFILRNDRLDK 
                 831 
                 0.77 
               
               
                 18 
                 LPPNLTSASIGNNQQP 
                 688 
                 0.77 
               
               
                 18 
                 EIFWLMLKHMRVMMKK 
                 569 
                 0.77 
               
               
                 18 
                 RHSVSEHPSRKHSVGR 
                 1983 
                 0.77 
               
               
                 18 
                 FVRLDEDSQHRNIVAW 
                 1896 
                 0.77 
               
               
                 18 
                 TQQQPAAVTAARRRYF 
                 1759 
                 0.77 
               
               
                 18 
                 DTLIRYGGSFPQEFWD 
                 1542 
                 0.77 
               
               
                 18 
                 HTEGDQLETLQQDQPP 
                 102 
                 0.77 
               
               
                 19 
                 SRTLSIPLQVTALDCI 
                 219 
                 0.76 
               
               
                 19 
                 QDMRQRSDSRSTTATF 
                 139 
                 0.76 
               
               
                 19 
                 MAEAENDPTNELNQTS 
                 1 
                 0.76 
               
               
                 20 
                 SASIGNNQQPPTHSVP 
                 694 
                 0.75 
               
               
                 20 
                 RQIYNMFIYSKSSQNQ 
                 315 
                 0.75 
               
               
                 20 
                 KQESGSAATYVHILFR 
                 1850 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 704 
                 728 
                 722 
                 PTHSVPSEYILKHQAVECLVVILES 
               
               
                 1595 
                 1629 
                 1625 
                 IQALRHMITLFTHYFDALEYMLGRVLELLTLCICQ 
               
               
                 1906 
                 1921 
                 1916 
                 RNIVAWRPVVVDVIEG 
               
               
                 1441 
                 1450 
                 1445 
                 FPDLVVCLTE 
               
               
                 1882 
                 1900 
                 1887 
                 EAALIPLCVDIISGFVRLD 
               
               
                 1778 
                 1794 
                 1783 
                 ITSCVLQLLMIETVHEL 
               
               
                 1555 
                 1573 
                 1567 
                 FWDVLWRQLLYPIFVVLQS 
               
               
                 558 
                 578 
                 565 
                 SSVPKVFEVCCEIFWLMLKHM 
               
               
                 922 
                 935 
                 927 
                 TAYVLAYSVILLNT 
               
               
                 1638 
                 1651 
                 1644 
                 GSNCLQQLILQNVE 
               
               
                 538 
                 553 
                 549 
                 MTFLQAIRPHLCLSLS 
               
               
                 465 
                 490 
                 477 
                 DEIYVKDAFLVFRALCKLSHKVLSHE 
               
               
                 207 
                 248 
                 214 
                 DPEILFYPLLLASRTLSIPLQVTALDCIGKLITYSYF 
               
               
                   
                   
                   
                 AFPSA 
               
               
                 283 
                 317 
                 296 
                 PIEIQQQIIKSLLAAVLNDKIVVHGAGLLKAVRQI 
               
               
                 503 
                 529 
                 510 
                 KLLSLHLIHYLINNHVIIFTTPLLTLK 
               
               
                 158 
                 175 
                 169 
                 RSSVVSSTVFIVTALDAI 
               
               
                 1166 
                 1182 
                 1170 
                 ILTCVSQLDRLQLLSDG 
               
               
                 1139 
                 1154 
                 1150 
                 AKNVEAVKILLDVALS 
               
               
                 1324 
                 1338 
                 1329 
                 NTTVVFFALDSLRQL 
               
               
                 1116 
                 1128 
                 1122 
                 TPRVAFVTALAKF 
               
               
                 1935 
                 1947 
                 1942 
                 DTFYPLAVDLLGR 
               
               
                 370 
                 382 
                 376 
                 SESVTIEPVVSPP 
               
               
                 1370 
                 1385 
                 1380 
                 AVTVKDMILRCLIQMI 
               
               
                 1856 
                 1866 
                 1861 
                 AATYVHILFRM 
               
               
                 1283 
                 1294 
                 1288 
                 RTYSLQKLVEIS 
               
               
                 1194 
                 1200 
                 1199 
                 AGVVPPS 
               
               
                 644 
                 677 
                 657 
                 QNIIEQLSRYASIPTVVNPLQQQQYHELHVKASS 
               
               
                 1513 
                 1523 
                 1517 
                 WYPILIAFQDI 
               
               
                 261 
                 277 
                 273 
                 EQPPLIERAIDAICDCF 
               
               
                 1105 
                 1113 
                 1107 
                 AIRISCTFD 
               
               
                 34 
                 44 
                 35 
                 APEVVAESKPA 
               
               
                 585 
                 598 
                 595 
                 ELEVFMKEIYLAIL 
               
               
                 1797 
                 1823 
                 1803 
                 NDKVYAQIPSHELLRLMGLLKKSYQFA 
               
               
                 389 
                 404 
                 398 
                 ASDVASVAADQPVSKE 
               
               
                 1459 
                 1475 
                 1465 
                 KKSLQAIELLKSTVAKM 
               
               
                 1968 
                 1989 
                 1983 
                 RLGLPVRPTPTPVSPRHSVSEH 
               
               
                 1254 
                 1271 
                 1265 
                 SHEAIIDFVRALSEVSWQ 
               
               
                 993 
                 1018 
                 998 
                 NAAHPAPVPSGLASRAGQVFATVGRD 
               
               
                 1431 
                 1439 
                 1435 
                 RFGVVITQG 
               
               
                 621 
                 629 
                 627 
                 EPRALVEMY 
               
               
                 816 
                 824 
                 819 
                 GVKLALQEG 
               
               
                 1478 
                 1486 
                 1482 
                 TPECPLSHR 
               
               
                 338 
                 357 
                 351 
                 TQMVSTVFDRLRVRLDLREL 
               
               
                 762 
                 771 
                 768 
                 APAFLASPRV 
               
               
                 78 
                 85 
                 79 
                 HEPSVTSP 
               
               
                 1038 
                 1045 
                 1040 
                 LYRSLIRA 
               
               
                 1585 
                 1591 
                 1589 
                 ELSVWLS 
               
               
                 1051 
                 1067 
                 1061 
                 VKEALSRFIFATSVQHA 
               
               
                 1954 
                 1963 
                 1958 
                 RLAIQGLFQR 
               
               
                 802 
                 809 
                 803 
                 LTNVIQQF 
               
               
                 1535 
                 1548 
                 1542 
                 RALTYLFDTLIRYG 
               
               
                 876 
                 892 
                 888 
                 RRFVDALRSFLQHFRLP 
               
               
                 1354 
                 1364 
                 1361 
                 QKDFLKPFEHV 
               
               
                 1662 
                 1668 
                 1665 
                 VGAFIEL 
               
               
                 1308 
                 1322 
                 1318 
                 IWEVLGQHFNQVGCH 
               
               
                 833 
                 839 
                 837 
                 DIAAFIL 
               
               
                 789 
                 795 
                 792 
                 PSQVEKV 
               
               
                 1762 
                 1769 
                 1763 
                 QPAAVTAA 
               
               
                 1400 
                 1408 
                 1403 
                 FGVFSFAAR 
               
               
                 1418 
                 1427 
                 1425 
                 NMAFEHVTQI 
               
               
                 1079 
                 1085 
                 1081 
                 LSGLSAP 
               
               
                 192 
                 199 
                 193 
                 KNALANVK 
               
               
                 25 
                 32 
                 29 
                 GVDVATEP 
               
               
                 1240 
                 1246 
                 1243 
                 VKGVDRI 
               
               
                 1686 
                 1692 
                 1690 
                 TVTLKTP 
               
               
                 966 
                 973 
                 972 
                 PDEYLGSI 
               
               
                 1674 
                 1680 
                 1677 
                 AYELFTA 
               
               
                 735 
                 741 
                 740 
                 QRSVDPT 
               
               
                 1846 
                 1851 
                 1848 
                 PNLLKQ 
               
               
                 689 
                 695 
                 691 
                 PPNLTSA 
               
               
                 14 
                 20 
                 17 
                 QTSVTQA 
               
               
                 980 
                 985 
                 985 
                 NEIVLD 
               
               
                 1500 
                 1505 
                 1502 
                 TQQLTK 
               
               
                 781 
                 787 
                 782 
                 STPVPDD 
               
               
                 420 
                 426 
                 425 
                 VTTVNDN 
               
               
                   
               
            
           
           
               
               
            
               
                 70.  Aspergillus nidulans  AN7704.2 
                   
               
               
                 MARSFVCHVSDSITTLLFRSLSFVYCMPEFKISAALEGHGDDVRAVAFPNSKAVFSASRDATVRLWKLVSSP 
               
               
                   
               
               
                 PPTFDYTIICHGSAFINALAYYPPTPDFPEGLVFSGGQDTIIEARQPGKTSNDNADAMLLGHAHTVCSLDVC 
               
               
                   
               
               
                 PEGEWIVSGSWDSTARLWRIGKWESEVVLEDHQGSVWAVLAYDKNTIITDSRDVVRALCKLPPTHPTGANFV 
               
               
                   
               
               
                 SASNDGVIRLFTLQGDLVGELHGHESFIYSLAVLPTGELVSSGEDRTVRIWNETQCVQTITHPAISVWGVAV 
               
               
                   
               
               
                 CPENGDIVTGASDRVTRVFTRAPERQASAEVLQQFETAVRESAIPAQQVGKINKEKLPGPEFLQQKSGTKDG 
               
               
                   
               
               
                 QVQMIREANGSVTAHTWSAALGRWESVGTVVDSAGSSGRKTEYLGQDYDFVFDVDVEDGKPPLKLPYNLSQN 
               
               
                   
               
               
                 PYEAATKFIGDNELPMSYLDQVAQFIVQNTQGATIGQPSQETAGGPDPWGQDRRYRPGDAPAQSTAIPESRP 
               
               
                   
               
               
                 KVLPQKTYLSIKSANLKVISKKLNELNGKLVSEGSKDLSLSPSELETIVSLCNELEASNTLKGPSAVEAVVI 
               
               
                   
               
               
                 LLFKVATVWPAANRLPGLDLLRLFAAATPVTATADYNGKDLVSGIIESGVFDAPVNVNNAMLSVRMFANLFE 
               
               
                   
               
               
                 TDAGRRLIIDRFDQVIAAIRTCLTNSGSSVNRNLTIAVATLYINIAVFSTSEARNLSIESNQRGLILLEELT 
               
               
                   
               
               
                 GMLRNEKDSEAVYRSLVALGTLVKELVSEVKAAAKEVYDLGAILQAISSSNLGKEPRIKGIVAEIKDSLP 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 QDTIIEARQPGKTSND 
                 110 
                 0.97 
               
               
                 2 
                 VSGIIESGVFDAPVNV 
                 618 
                 0.95 
               
               
                 2 
                 PDPWGQDRRYRPGDAP 
                 478 
                 0.95 
               
               
                 3 
                 QPSQETAGGPDPWGQD 
                 469 
                 0.92 
               
               
                 3 
                 DGKPPLKLPYNLSQNP 
                 418 
                 0.92 
               
               
                 4 
                 TKFIGDNELPMSYLDQ 
                 438 
                 0.91 
               
               
                 5 
                 NALAYYPPTPDFPEGL 
                 89 
                 0.90 
               
               
                 5 
                 PAQSTAIPESRPKVLP 
                 493 
                 0.90 
               
               
                 6 
                 RALCKLPPTHPTGANF 
                 200 
                 0.89 
               
               
                 7 
                 VQTITHPAISVWGVAV 
                 273 
                 0.88 
               
               
                 8 
                 DGQVQMIREANGSVTA 
                 359 
                 0.87 
               
               
                 8 
                 AALEGHGDDVRAVAFP 
                 34 
                 0.87 
               
               
                 8 
                 QGSVWAVLAYDKNTII 
                 177 
                 0.87 
               
               
                 8 
                 EWIVSGSWDSTARLWR 
                 148 
                 0.87 
               
               
                 9 
                 EFLQQKSGTKDGQVQM 
                 349 
                 0.86 
               
               
                 10 
                 KLVSSPPPTFDYTIIC 
                 67 
                 0.85 
               
               
                 10 
                 NGSVTAHTWSAALGRW 
                 369 
                 0.85 
               
               
                 10 
                 GELVSSGEDRTVRIWN 
                 253 
                 0.85 
               
               
                 11 
                 TPDFPEGLVFSGGQDT 
                 97 
                 0.84 
               
               
                 11 
                 LLFKVATVWPAANRLP 
                 577 
                 0.84 
               
               
                 11 
                 KNTIITDSRDVVRALC 
                 188 
                 0.84 
               
               
                 12 
                 ELTGMLRNEKDSEAVY 
                 718 
                 0.83 
               
               
                 12 
                 MLLGHAHTVCSLDVCP 
                 130 
                 0.83 
               
               
                 13 
                 KVLPQKTYLSIKSANL 
                 505 
                 0.82 
               
               
                 13 
                 RKTEYLGQDYDFVFDV 
                 399 
                 0.82 
               
               
                 14 
                 YTIICHGSAFINALAY 
                 78 
                 0.81 
               
               
                 14 
                 EVKAAAKEVYDLGAIL 
                 749 
                 0.81 
               
               
                 14 
                 DQVIAAIRTCLTNSGS 
                 661 
                 0.81 
               
               
                 14 
                 AATPVTATADYNGKDL 
                 602 
                 0.81 
               
               
                 14 
                 SWDSTARLWRIGKWES 
                 154 
                 0.81 
               
               
                 15 
                 SASRDATVRLWKLVSS 
                 56 
                 0.80 
               
               
                 15 
                 EGSKDLSLSPSELETI 
                 537 
                 0.80 
               
               
                 15 
                 YRPGDAPAQSTAIPES 
                 487 
                 0.80 
               
               
                 16 
                 VTGASDRVTRVFTRAP 
                 296 
                 0.79 
               
               
                 16 
                 PPTHPTGANFVSASND 
                 206 
                 0.79 
               
               
                 17 
                 LQAISSSNLGKEPRIK 
                 764 
                 0.78 
               
               
                 17 
                 SLSPSELETIVSLCNE 
                 543 
                 0.78 
               
               
                 17 
                 RESAIPAQQVGKINKE 
                 328 
                 0.78 
               
               
                 18 
                 VEAVVILLFKVATVWP 
                 571 
                 0.77 
               
               
                 18 
                 VGKINKEKLPGPEFLQ 
                 337 
                 0.77 
               
               
                 19 
                 DQVAQFIVQNTQGATI 
                 452 
                 0.76 
               
               
                 20 
                 SGVFDAPVNVNNAMLS 
                 624 
                 0.75 
               
               
                 20 
                 RWESVGTVVDSAGSSG 
                 383 
                 0.75 
               
               
                 20 
                 DRTVRIWNETQCVQTI 
                 261 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 129 
                 154 
                 141 
                 AMLLGHAHTVCSLDVCPEGEWIVSGS 
               
               
                 567 
                 587 
                 576 
                 GPSAVEAVVILLFKVATVWPA 
               
               
                 4 
                 29 
                 7 
                 SFVCHVSDSITTLLFRSLSFVYCMPE 
               
               
                 269 
                 291 
                 286 
                 ETQCVQTITHPAISVWGVAVCPE 
               
               
                 195 
                 208 
                 201 
                 SRDVVRALCKLPPT 
               
               
                 239 
                 258 
                 247 
                 GHESFIYSLAVLPTGELVSS 
               
               
                 177 
                 186 
                 183 
                 QGSVWAVLAY 
               
               
                 730 
                 770 
                 734 
                 EAVYRSLVALGTLVKELVSEVKAAAKEVYDLGAILQAISSS 
               
               
                 448 
                 462 
                 456 
                 MSYLDQVAQFIVQNT 
               
               
                 405 
                 417 
                 413 
                 GQDYDFVFDVDVE 
               
               
                 683 
                 698 
                 688 
                 TIAVATLYINIAVFST 
               
               
                 549 
                 559 
                 553 
                 LETIVSLCNEL 
               
               
                 62 
                 98 
                 66 
                 TVRLWKLVSSPPPTFDYTIICHGSAFINALAYYPPTP 
               
               
                 42 
                 57 
                 46 
                 DVRAVAFPNSKAVFSA 
               
               
                 223 
                 237 
                 226 
                 VIRLFTLQGDLVGEL 
               
               
                 712 
                 718 
                 716 
                 GLILLEE 
               
               
                 169 
                 175 
                 174 
                 SEVVLED 
               
               
                 593 
                 609 
                 599 
                 GLDLLRLFAAATPVTAT 
               
               
                 387 
                 394 
                 389 
                 VGTVVDSA 
               
               
                 422 
                 432 
                 424 
                 PLKLPYNLSQN 
               
               
                 328 
                 339 
                 334 
                 RESAIPAQQVGK 
               
               
                 623 
                 633 
                 628 
                 ESGVFDAPVNV 
               
               
                 654 
                 673 
                 668 
                 RLIIDRFDQVIAAIRTCLTN 
               
               
                 503 
                 525 
                 509 
                 RPKVLPQKTYLSIKSANLKVISK 
               
               
                 615 
                 621 
                 619 
                 KDLVSGI 
               
               
                 316 
                 326 
                 320 
                 SAEVLQQFETA 
               
               
                 101 
                 108 
                 103 
                 PEGLVFSG 
               
               
                 31 
                 37 
                 33 
                 KISAALE 
               
               
                 636 
                 643 
                 641 
                 AMLSVRMF 
               
               
                 532 
                 537 
                 533 
                 GKLVSE 
               
               
                 341 
                 547 
                 544 
                 DLSLSPS 
               
               
                 347 
                 354 
                 348 
                 GPEFLQQK 
               
               
                 779 
                 787 
                 779 
                 KGIVAEIKD 
               
               
                 303 
                 309 
                 305 
                 VTRVFTR 
               
               
                 213 
                 218 
                 216 
                 ANFVSA 
               
               
                   
               
            
           
           
               
               
            
               
                 71.  Saccharomyces cerevisiae  YBL024w 
                   
               
               
                 MARRKNFKKGNKKTFGARDDSRAQKNWSELVKENEKWEKYYKTLALFPEDQWEEFKKTCQAPLPLTFRITGS 
               
               
                   
               
               
                 RKHAGEVLNLFKERHLPNLTNVEFEGEKIKAPVELPWYPDHLAWQLDVPKTVIRKNEQFAKTQRFLVVENAV 
               
               
                   
               
               
                 GNISRQEAVSMIPPIVLEVKPHHTVLDMCAAPGSKTAQLIEALHKDTDEPSGFVVANDADARRSHMLVHQLK 
               
               
                   
               
               
                 RLNSANLMVVNHDAQFFPRIRLHGNSNNKNDVLKFDRILCDVPCSGDGTMRKNVNVWKDWNTQAGLGLHAVQ 
               
               
                   
               
               
                 LNILNRGLHLLKNNGRLVYSTCSLNPIENEAVVAEALRKWGDKIRLVNCDDKLPGLIRSKGVSKWPVYDRNL 
               
               
                   
               
               
                 TEKTKGDEGTLDSFFSPSEEEASKFNLQNCMRVYPHQQNTGGFFITVFEKVEDSTEAATEKLSSETPALESE 
               
               
                   
               
               
                 GPQTKKIKVEEVQKKERLPRDANEEPFVFVDPQHEALKVCWDFYGIDNIFDRNTCLVRNATGEPTRVVYTVC 
               
               
                   
               
               
                 PALKDVIQANDDRLKIIYSGVKLFVSQRSDIECSWRIQSESLPIMKHHMKSNRIVEANLEMLKHLLIESFPN 
               
               
                   
               
               
                 FDDIRSKNIDNDFVEKMTKLSSGCAFIDVSRNDPAKENLFLPVWKGNKCINLMVCKEDTHELLYRIFGIDAN 
               
               
                   
               
               
                 AKATPSAEEKEKEKETTESPAETTTGTSTEAPSAAN 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 PGLIRSKGVSKWPVYD 
                 342 
                 0.94 
               
               
                 2 
                 HLLIESFPNFDDIRSK 
                 568 
                 0.93 
               
               
                 2 
                 DVPCSGDGTMRKNVNV 
                 257 
                 0.93 
               
               
                 3 
                 KEKEKETTESPAETTT 
                 658 
                 0.90 
               
               
                 3 
                 KKTFGARDDSRAQKNW 
                 12 
                 0.90 
               
               
                 3 
                 PVELPWYPDHLAWQLD 
                 104 
                 0.90 
               
               
                 4 
                 NFKKGNKKTFGARDDS 
                 6 
                 0.88 
               
               
                 5 
                 LLYRIFGIDANAKATP 
                 638 
                 0.87 
               
               
                 5 
                 IRSKNIDNDFVEKMTK 
                 580 
                 0.87 
               
               
                 6 
                 RLPRDANEEPFVFVDP 
                 449 
                 0.86 
               
               
                 6 
                 KGVSKWPVYDRNLTEK 
                 348 
                 0.86 
               
               
                 7 
                 EVQKKERLPRDANEEP 
                 443 
                 0.85 
               
               
                 7 
                 LRKWGDKIRLVNCDDK 
                 325 
                 0.85 
               
               
                 7 
                 GRLVYSTCSLNPIENE 
                 303 
                 0.85 
               
               
                 8 
                 RNATGEPTRVVYTVCP 
                 490 
                 0.84 
               
               
                 8 
                 HKDTDEPSGFVVANDA 
                 188 
                 0.84 
               
               
                 9 
                 GIDANAKATPSAEEKE 
                 644 
                 0.83 
               
               
                 9 
                 LPVWKGNKCINLMVCK 
                 617 
                 0.83 
               
               
                 9 
                 SPSEEEASKFNLQNCM 
                 376 
                 0.83 
               
               
                 10 
                 TESPAETTTGTSTEAP 
                 665 
                 0.82 
               
               
                 10 
                 ENEKWEKYYKTLALFP 
                 33 
                 0.82 
               
               
                 10 
                 ARRSHMLVHQLKRLNS 
                 205 
                 0.82 
               
               
                 10 
                 AKTQRFLVVENAVGNI 
                 132 
                 0.82 
               
               
                 10 
                 PKTVIRKNEQFAKTQR 
                 121 
                 0.82 
               
               
                 11 
                 KKTCQAPLPLTFRITG 
                 56 
                 0.81 
               
               
                 12 
                 FVSQRSDIECSWRIQS 
                 528 
                 0.80 
               
               
                 12 
                 EKTKGDEGTLDSFFSP 
                 362 
                 0.80 
               
               
                 13 
                 KDVIQANDDRLKIIYS 
                 508 
                 0.79 
               
               
                 13 
                 IDNIFDRNTCLVRNAT 
                 478 
                 0.79 
               
               
                 13 
                 LFPEDQWEEFKKTCQA 
                 46 
                 0.79 
               
               
                 13 
                 ALESEGPQTKKIKVEE 
                 428 
                 0.79 
               
               
                 13 
                 FPRIRLHGNSNNKNDV 
                 233 
                 0.79 
               
               
                 13 
                 PGSKTAQLIEALHKDT 
                 176 
                 0.79 
               
               
                 13 
                 QEAVSMIPPIVLEVKP 
                 150 
                 0.79 
               
               
                 14 
                 TFRITGSRKHAGEVLN 
                 66 
                 0.78 
               
               
                 14 
                 LSSGCAFIDVSRNDPA 
                 596 
                 0.78 
               
               
                 14 
                 NRIVEANLEMLKHLLI 
                 556 
                 0.78 
               
               
                 14 
                 EDSTEAATEKLSSETP 
                 412 
                 0.78 
               
               
                 15 
                 SWRIQSESLPIMKHHM 
                 538 
                 0.77 
               
               
                 15 
                 PFVFVDPQHEALKVCW 
                 458 
                 0.77 
               
               
                 15 
                 KLSSETPALESEGPQT 
                 421 
                 0.77 
               
               
                 16 
                 HEALKVCWDFYGIDNI 
                 466 
                 0.76 
               
               
                 16 
                 FVVANDADARRSHMLV 
                 197 
                 0.76 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 497 
                 513 
                 502 
                 TRVVYTVCPALKDVIQA 
               
               
                 248 
                 262 
                 257 
                 VLKFDRILCDVPCSG 
               
               
                 625 
                 633 
                 628 
                 CINLMVCKE 
               
               
                 150 
                 176 
                 160 
                 QEAVSMIPPIVLEVKPHHTVLDMCAAP 
               
               
                 304 
                 313 
                 308 
                 RLVYSTCSLN 
               
               
                 57 
                 68 
                 62 
                 KTCQAPLPLTFR 
               
               
                 135 
                 143 
                 141 
                 QRFLVVENA 
               
               
                 518 
                 532 
                 528 
                 LKIIYSGVKLFVSQR 
               
               
                 317 
                 324 
                 322 
                 NEAVVAEA 
               
               
                 457 
                 475 
                 469 
                 EPFVFVDPQHEALKVCWDF 
               
               
                 597 
                 605 
                 603 
                 SSGCAFIDV 
               
               
                 281 
                 291 
                 285 
                 GLGLHAVQLNI 
               
               
                 208 
                 218 
                 212 
                 SHMLVHQLKRL 
               
               
                 195 
                 202 
                 197 
                 SGFVVAND 
               
               
                 613 
                 620 
                 618 
                 ENLFLPVW 
               
               
                 347 
                 358 
                 353 
                 SKGVSKWPVYDR 
               
               
                 390 
                 397 
                 393 
                 CMRVYPHQ 
               
               
                 566 
                 574 
                 569 
                 LKHLLIESF 
               
               
                 102 
                 124 
                 121 
                 KAPVELPWYPDHLAWQLDVPKTV 
               
               
                 332 
                 345 
                 334 
                 IRLVNCDDKLPGLI 
               
               
                 41 
                 49 
                 43 
                 YKTLALFPE 
               
               
                 404 
                 410 
                 408 
                 FITVFEK 
               
               
                 222 
                 237 
                 223 
                 NLMVVNHDAQFFPRIR 
               
               
                 180 
                 187 
                 185 
                 TAQLIEAL 
               
               
                 484 
                 491 
                 489 
                 RNTCLVRN 
               
               
                 636 
                 644 
                 641 
                 HELLYRIFG 
               
               
                 438 
                 444 
                 442 
                 KIKVEEV 
               
               
                 294 
                 299 
                 297 
                 RGLHLL 
               
               
                 76 
                 83 
                 81 
                 AGEVLNLF 
               
               
                 543 
                 550 
                 549 
                 SESLPIMK 
               
               
                 88 
                 94 
                 91 
                 LPNLTNV 
               
               
                 534 
                 540 
                 540 
                 DIECSWR 
               
               
                 424 
                 429 
                 425 
                 SETPAL 
               
               
                   
               
            
           
           
               
               
            
               
                 72.  Aspergillus fumigatus  CAF32099 
                   
               
               
                 MATFARPVASSISGIEFGVYSDEDIKSISVKRIHNTPTLDSFNNPVPGGLYDPALGAWGDHLSLVIAYFGPF 
               
               
                   
               
               
                 WLTAFSCTTCRQNSWSCTGHPGHIELPVRVYNVTFFDQLYRLLRAQCVYCHRFQMARVQINAYVCKLRLLQY 
               
               
                   
               
               
                 GLVDEVEAIEAMGTGQGNKKKSAKDADDSGSEEEDDDDLVARRNAYVKKVIREAHAAGRLKGIMSGAKNPMA 
               
               
                   
               
               
                 AEQRRTLVKQFFKDLVSIKKCSSCSGYRRDRFSKIFRKPLPEKSRLAMVQAGFQAPNSLILLQQAKKFDMKT 
               
               
                   
               
               
                 KESMANGISDTANAVSESHGAEEEVARGNAVVAQAESKKSAAGDAGQYMPSPEVHAAMVLLFEKEKEILSLI 
               
               
                   
               
               
                 YNSRPLPKKEAKVSPDMFFIKNILVPPNKYRPAAPQGPGEIMEAQQNTPFTQILKNCDIINQISKERQNAGA 
               
               
                   
               
               
                 DSVTRMRDYRDLLHAIVQLQDTVNGLIDKERGASGPAAGQAANGIKQILEKKEGLFRKNMMGKRVNFAARSV 
               
               
                   
               
               
                 ISPDPNIETNEIGVPLVFAKKLTYPEPVTNHNFWEMKQAVINGPDKYPGATAIENELGQVTNLKFKSLDERT 
               
               
                   
               
               
                 ALANQLLAPSNWRMKGARNKKVYRHLTTGDVVLMNRQPTLHKPSIMGHKARVLANERVIRMHYANCNTYNAD 
               
               
                   
               
               
                 FDGDEMNMHFPQNELARAEAMMLADADHQYLVATSGKPLRGLIQDHISMGTWFTCRDTFFDEEDYHELLYSC 
               
               
                   
               
               
                 LRPENSHTVTERIQLVEPTLLKPKRLWTGKQVITTILKNIMPPGRAGLNLKSKSSTPGDRWGEGNEEGTVIF 
               
               
                   
               
               
                 KDGEMLCGILDKKQIGPTAGGLIDAIHEVYGHTIAGRLISILGRLLTRYLNMRAFTCGIDDLRLTKEGDRLR 
               
               
                   
               
               
                 KEKLSQAASIGREVALKYVTLDQTTVPDQDAELRRRLEDVLRDDDKQSGLDSVSNARTAKLSTEITQACLPK 
               
               
                   
               
               
                 GLAKPFPWNQMQSMTISGAKGSSVNANLISCNLGQQVLEGRRVPVMISGKTLPSFRAFDTHPMAGGYVCGRF 
               
               
                   
               
               
                 LTGIKPQEYYFHAMAGREGLIDTAVKTSRSGYLQRCLIKGMEGLRAEYDTSVRESSDGSIVQFLYGEDGLDI 
               
               
                   
               
               
                 TKQVHLKDFDFLTSNYVSIMQSVNLTSDFHNLEKDEVTAWHKDAMKKVRKTGKVDAMDPVLSVYHPGGNLGS 
               
               
                   
               
               
                 TSEAFSQALKKYEDTNPDKLLRDKKKNIDGLISKKAFNTLMNMKYLKSVVDPGEAVGIVASQSIGEPSTQMT 
               
               
                   
               
               
                 LNTFHLAGHSAKNVTLGIPRLREIVMTASAHIMTPTMTLILNEELSKEHSERFAKAISKLSIAEVIDKVKVK 
               
               
                   
               
               
                 ERIATAGSRFKVYDVEIALFPAEEYTKEYAITTKDVQNTLQNKFIPKLVKLTRAELKRRNDEKSLKSFSTAQ 
               
               
                   
               
               
                 PEIGVSVGVIEEGPRGPDREVEPAQDDDEDDEDDAKRARSGQNRSNQVSYEGPEQEEIDMVRQQDAVEDDED 
               
               
                   
               
               
                 EDESGEDRRQDSDVDMDDSDEETDEETKDTKLREEDIKGKYGEVTQFKFNPSKGTSCVVQLQYDISTPKLLL 
               
               
                   
               
               
                 LPLVEEAARSAVIQSIPGLGNCTYVEADPVKGEPAHVITEGVNLLAMRDYQDIIKPHSIYTNSIHHMLMLYG 
               
               
                   
               
               
                 VEAARASIVREMSDVFQGHSISVDNRHLNLIGDVMTQSGGFRAFNRNGLVKDSSSPLAKMSFETTVGFLKDA 
               
               
                   
               
               
                 VIERDFDNLKSPSSRIVAGRSGMVGTGAFDVLAPVA 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 QDHISMGTWFTCRDTF 
                 692 
                 0.96 
               
               
                 2 
                 GVIEEGPRGPDREVEP 
                 1376 
                 0.95 
               
               
                 2 
                 EYAITTKDVQNTLQNK 
                 1324 
                 0.95 
               
               
                 3 
                 VEPAQDDDEDDEDDAK 
                 1389 
                 0.93 
               
               
                 3 
                 HRFQMARVQINAYVCK 
                 123 
                 0.93 
               
               
                 4 
                 PAAPQGPGEIMEAQQN 
                 392 
                 0.92 
               
               
                 4 
                 VKRIHNTPTLDSFNNP 
                 30 
                 0.92 
               
               
                 4 
                 GSEEEDDDDLVARRNA 
                 174 
                 0.92 
               
               
                 4 
                 MVRQQDAVEDDEDEDE 
                 1428 
                 0.92 
               
               
                 4 
                 SQSIGEPSTQMTLNTF 
                 1213 
                 0.92 
               
               
                 5 
                 ISGIEFGVYSDEDIKS 
                 12 
                 0.91 
               
               
                 5 
                 EDTNPDKLLRDKKKNI 
                 1165 
                 0.91 
               
               
                 6 
                 ERVIRMHYANCNTYNA 
                 632 
                 0.90 
               
               
                 6 
                 HKPSIMGHKARVLANE 
                 617 
                 0.90 
               
               
                 7 
                 STEITQACLPKGLAKP 
                 926 
                 0.89 
               
               
                 7 
                 QNSWSCTGHPGHIELP 
                 84 
                 0.89 
               
               
                 7 
                 TILKNIMPPGRAGLNL 
                 755 
                 0.89 
               
               
                 7 
                 TNEIGVPLVFAKKLTY 
                 513 
                 0.89 
               
               
                 7 
                 PGEIMEAQQNTPFTQI 
                 398 
                 0.89 
               
               
                 7 
                 ASAHIMTPTMTLILNE 
                 1252 
                 0.89 
               
               
                 7 
                 EVTAWHKDAMKKVRKT 
                 1116 
                 0.89 
               
               
                 8 
                 PSNWRMKGARNKKVYR 
                 585 
                 0.88 
               
               
                 9 
                 PVMISGKTLPSFRAFD 
                 980 
                 0.87 
               
               
                 9 
                 HPGHIELPVPVYNVTF 
                 92 
                 0.87 
               
               
                 9 
                 TVTERIQLVEPTLLKP 
                 728 
                 0.87 
               
               
                 9 
                 GIMSGAKNPMAAEQRR 
                 206 
                 0.87 
               
               
                 9 
                 NGLVKDSSSPLAKMSF 
                 1631 
                 0.87 
               
               
                 9 
                 AIEAMGTGQGNKKKSA 
                 152 
                 0.87 
               
               
                 10 
                 DEDIKSISVKRIHNTP 
                 22 
                 0.86 
               
               
                 10 
                 AVIQSIPGLGNCTYVE 
                 1523 
                 0.86 
               
               
                 10 
                 LKSVVDPGEAVGIVAS 
                 1198 
                 0.86 
               
               
                 11 
                 HPMAGGYVCGRFLTGI 
                 997 
                 0.85 
               
               
                 11 
                 NMRAFTCGIDDLRLTK 
                 843 
                 0.85 
               
               
                 11 
                 KQAVINGPDKYPGATA 
                 541 
                 0.85 
               
               
                 11 
                 PDPNIETNEIGVPLVF 
                 507 
                 0.85 
               
               
                 11 
                 KEGLFRKNMMGKRVNF 
                 484 
                 0.85 
               
               
                 11 
                 KCSSCSGYRRDRFSKI 
                 236 
                 0.85 
               
               
                 11 
                 HHMLMLYGVEAARASI 
                 1577 
                 0.85 
               
               
                 11 
                 PVLSVYHPGGNLGSTS 
                 1139 
                 0.85 
               
               
                 11 
                 QSVNLTSDFHNLEKDE 
                 1101 
                 0.85 
               
               
                 11 
                 RCLIKGMEGLRAEYDT 
                 1043 
                 0.85 
               
               
                 12 
                 SMTISGAKGSSVNANL 
                 949 
                 0.84 
               
               
                 12 
                 YVTLDQTTVPDQDAEL 
                 882 
                 0.84 
               
               
                 12 
                 AGGLIDAIHEVYGHTI 
                 811 
                 0.84 
               
               
                 12 
                 GFLKDAVIERDFDNLK 
                 1651 
                 0.84 
               
               
                 12 
                 EELSKEHSERFAKAIS 
                 1267 
                 0.84 
               
               
                 13 
                 TAFSCTTCRQNSWSCT 
                 75 
                 0.83 
               
               
                 13 
                 PGGLYDPALGAWGDHL 
                 47 
                 0.83 
               
               
                 13 
                 AHVITEGVNLLAMRDY 
                 1547 
                 0.83 
               
               
                 13 
                 DVDMDDSDEETDEETK 
                 1453 
                 0.83 
               
               
                 14 
                 KSKSSTPGDRWGEGNE 
                 771 
                 0.82 
               
               
                 14 
                 HGAEEEVARGNAVVAQ 
                 307 
                 0.82 
               
               
                 14 
                 KKSAKDADDSGSEEED 
                 164 
                 0.82 
               
               
                 14 
                 EDESGEDRRQDSDVDM 
                 1441 
                 0.82 
               
               
                 14 
                 TGIKPQEYYFHAMAGR 
                 1010 
                 0.82 
               
               
                 15 
                 ARTAKLSTEITQACLP 
                 920 
                 0.81 
               
               
                 15 
                 FAKKLTYPEPVTNHNF 
                 522 
                 0.81 
               
               
                 15 
                 TRMRDYRDLLHAIVQL 
                 436 
                 0.81 
               
               
                 15 
                 IINQISKERQNAGADS 
                 419 
                 0.81 
               
               
                 15 
                 TLDSFNNPVPGGLYDP 
                 38 
                 0.81 
               
               
                 15 
                 MFFIKNILVPPNKYRP 
                 377 
                 0.81 
               
               
                 15 
                 TQSGGFRAFNRNGLVK 
                 1620 
                 0.81 
               
               
                 15 
                 LFPAEEYTKEYAITTK 
                 1315 
                 0.81 
               
               
                 15 
                 KERIATAGSRFKVYDV 
                 1296 
                 0.81 
               
               
                 15 
                 PSTQMTLNTFHLAGHS 
                 1219 
                 0.81 
               
               
                 16 
                 YNADFDGDEMNMHFPQ 
                 645 
                 0.80 
               
               
                 16 
                 KKVIREAHAAGRLKGI 
                 192 
                 0.80 
               
               
                 16 
                 SSRIVAGRSGMVGTGA 
                 1669 
                 0.80 
               
               
                 16 
                 QVSYEGPEQEEIDMVR 
                 1415 
                 0.80 
               
               
                 16 
                 EDDEDDAKRARSGQNR 
                 1397 
                 0.80 
               
               
                 16 
                 DGSIVQFLYGEDGLDI 
                 1065 
                 0.80 
               
               
                 16 
                 YFHAMAGREGLIDTAV 
                 1018 
                 0.80 
               
               
                 17 
                 GRLLTRYLNMRAFTCG 
                 835 
                 0.79 
               
               
                 17 
                 KKVYRHLTTGDVVLMN 
                 596 
                 0.79 
               
               
                 17 
                 ARSVISPDPNIETNEI 
                 501 
                 0.79 
               
               
                 17 
                 DVFQGHSISVDNRHLN 
                 1598 
                 0.79 
               
               
                 17 
                 PVKGEPAHVITEGVNL 
                 1541 
                 0.79 
               
               
                 17 
                 CTYVEADPVKGEPAHV 
                 1534 
                 0.79 
               
               
                 17 
                 DRRQDSDVDMDDSDEE 
                 1447 
                 0.79 
               
               
                 17 
                 AQCVYCHRFQMARVQI 
                 117 
                 0.79 
               
               
                 17 
                 TGKVDAMDPVLSVYHP 
                 1131 
                 0.79 
               
               
                 18 
                 RPENSHTVTERIQLVE 
                 722 
                 0.78 
               
               
                 18 
                 TKESMANGISDTANAV 
                 288 
                 0.78 
               
               
                 18 
                 PKLVKLTRAELKRRND 
                 1342 
                 0.78 
               
               
                 19 
                 REVALKYVTLDQTTVP 
                 876 
                 0.77 
               
               
                 19 
                 DKKQIGPTAGGLIDAI 
                 803 
                 0.77 
               
               
                 19 
                 GTVIFKDGEMLCGILD 
                 788 
                 0.77 
               
               
                 19 
                 GDRWGEGNEEGTVIFK 
                 778 
                 0.77 
               
               
                 19 
                 HELLYSCLRPENSHTV 
                 714 
                 0.77 
               
               
                 19 
                 AGQYMPSPEVHAAMVL 
                 333 
                 0.77 
               
               
                 19 
                 SDEETDEETKDTKLRE 
                 1459 
                 0.77 
               
               
                 20 
                 DVLRDDDKQSGLDSVS 
                 903 
                 0.76 
               
               
                 20 
                 HEVYGHTIAGRLISIL 
                 819 
                 0.76 
               
               
                 20 
                 KSLDERTALANQLLAP 
                 570 
                 0.76 
               
               
                 20 
                 IKQILEKKEGLFRKNM 
                 477 
                 0.76 
               
               
                 20 
                 MRDYQDIIKPHSIYTN 
                 1559 
                 0.76 
               
               
                 20 
                 VQLQYDISTPKLLLLP 
                 1499 
                 0.76 
               
               
                 20 
                 HPGGNLGSTSEAFSQA 
                 1145 
                 0.76 
               
               
                 21 
                 SGLDSVSNARTAKLST 
                 912 
                 0.75 
               
               
                 21 
                 DAELRRRLEDVLRDDD 
                 894 
                 0.75 
               
               
                 21 
                 GAWGDHLSLVIAYFGP 
                 56 
                 0.75 
               
               
                 21 
                 FSKIFRKPLPEKSRLA 
                 248 
                 0.75 
               
               
                 21 
                 AEVIDKVKVKERIATA 
                 1287 
                 0.75 
               
               
                 21 
                 RAEYDTSVRESSDGSI 
                 1053 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 1494 
                 1519 
                 1513 
                 GTSCVVQLQYDISTPKLLLLPLVEEA 
               
               
                 89 
                 125 
                 120 
                 CTGHPGHIELPVRVYNVTFFDQLYRLLRAQCVYCHRF 
               
               
                 1137 
                 1147 
                 1142 
                 MDPVLSVYHPG 
               
               
                 127 
                 153 
                 139 
                 MARVQINAYVCKLRLLQYGLVDEVEAI 
               
               
                 60 
                 82 
                 65 
                 DHLSLVIAYFGPFWLTAFSCTTC 
               
               
                 442 
                 458 
                 447 
                 RDLLHAIVQLQDTVNGL 
               
               
                 714 
                 723 
                 719 
                 HELLYSCLRP 
               
               
                 516 
                 532 
                 519 
                 IGVPLVFAKKLTYPEPV 
               
               
                 1038 
                 1047 
                 1043 
                 SGYLQRCLIK 
               
               
                 1682 
                 1689 
                 1688 
                 TGAFDVLA 
               
               
                 875 
                 893 
                 881 
                 GREVALKYVTLDQTTVPDQ 
               
               
                 339 
                 351 
                 345 
                 SPEVHAAMVLLFE 
               
               
                 221 
                 243 
                 234 
                 RTLVKQFFKDLVSIKKCSSCSGY 
               
               
                 1066 
                 1073 
                 1070 
                 GSIVQFLY 
               
               
                 1370 
                 1380 
                 1374 
                 EIGVSVGVIEE 
               
               
                 1198 
                 1205 
                 1199 
                 LKSVVDPG 
               
               
                 1001 
                 1012 
                 1006 
                 GGYVCGRFLTGI 
               
               
                 1278 
                 1298 
                 1292 
                 AKAISKLSIAEVIDKVKVKER 
               
               
                 182 
                 198 
                 192 
                 DLVARRNAYVKKVIREA 
               
               
                 272 
                 281 
                 278 
                 PNSLILLQQA 
               
               
                 1341 
                 1350 
                 1344 
                 IPKLVKLTRA 
               
               
                 729 
                 744 
                 738 
                 VTERIQLVEPTLLKPK 
               
               
                 1207 
                 1214 
                 1210 
                 AVGIVASQ 
               
               
                 673 
                 684 
                 679 
                 DADHQYLVATSG 
               
               
                 930 
                 941 
                 932 
                 TQACLPKGLAKP 
               
               
                 1305 
                 1318 
                 1311 
                 RFKVYDVEIALFPA 
               
               
                 1521 
                 1557 
                 1526 
                 RSAVIQSIPGLGNCTYVEADPVKGEPAHVITEGVNLL 
               
               
                 356 
                 364 
                 358 
                 ILSLIYNSR 
               
               
                 316 
                 323 
                 321 
                 GNAVVAQA 
               
               
                 1093 
                 1109 
                 1100 
                 TSNYVSIMQSVNLTSDF 
               
               
                 749 
                 757 
                 754 
                 GKQVITTIL 
               
               
                 1081 
                 1091 
                 1083 
                 TKQVHLKDFDF 
               
               
                 1648 
                 1660 
                 1655 
                 TTVGFLKDAVIER 
               
               
                 380 
                 388 
                 382 
                 IKNILVPPN 
               
               
                 798 
                 805 
                 801 
                 LCGILDKK 
               
               
                 961 
                 984 
                 967 
                 NANLISCNLGQQVLEGRRVPVMIS 
               
               
                 5 
                 22 
                 10 
                 ARPVASSISGIEFGVYSD 
               
               
                 47 
                 56 
                 48 
                 PGGLYDPALG 
               
               
                 579 
                 585 
                 580 
                 ANQLLAP 
               
               
                 625 
                 632 
                 627 
                 KARVLANE 
               
               
                 827 
                 841 
                 835 
                 AGRLISILGRLLTRY 
               
               
                 814 
                 825 
                 824 
                 LIDAIHEVYGHT 
               
               
                 1577 
                 1594 
                 1585 
                 HHMLMLYGVEAARASIVR 
               
               
                 498 
                 508 
                 502 
                 NFAARSVISPD 
               
               
                 1598 
                 1610 
                 1602 
                 DVFQGHSISVDNR 
               
               
                 27 
                 33 
                 31 
                 SISVKRI 
               
               
                 1563 
                 1575 
                 1569 
                 QDIIKPHSIYTNS 
               
               
                 604 
                 611 
                 605 
                 TGDVVLMN 
               
               
                 868 
                 873 
                 871 
                 LSQAAS 
               
               
                 1667 
                 1675 
                 1671 
                 SPSSRIVAG 
               
               
                 1030 
                 1035 
                 1031 
                 DTAVKT 
               
               
                 687 
                 694 
                 693 
                 LRGLIQDH 
               
               
                 1612 
                 1618 
                 1615 
                 LNLIGDV 
               
               
                 411 
                 422 
                 417 
                 TQILKNCDIINQ 
               
               
                 262 
                 269 
                 268 
                 LAMVQAGF 
               
               
                 1235 
                 1243 
                 1241 
                 AKNVTLGIP 
               
               
                 1227 
                 1233 
                 1231 
                 TFHLAGH 
               
               
                 1014 
                 1021 
                 1020 
                 PQEYYFHA 
               
               
                 1634 
                 1644 
                 1636 
                 VKDSSSPLAKM 
               
               
                 561 
                 567 
                 564 
                 LGQVTNL 
               
               
                 1245 
                 1257 
                 1246 
                 LREIVMTASAHIM 
               
               
                 986 
                 992 
                 991 
                 KTLPSFR 
               
               
                 1181 
                 1186 
                 1186 
                 DGLISK 
               
               
                 1157 
                 1163 
                 1159 
                 FSQALKK 
               
               
                 249 
                 255 
                 254 
                 SKIFRKP 
               
               
                 1261 
                 1267 
                 1266 
                 MTLILNE 
               
               
                 847 
                 854 
                 848 
                 FTCGIDDL 
               
               
                 368 
                 378 
                 376 
                 KKEAKVSPDMF 
               
               
                 542 
                 547 
                 545 
                 QAVING 
               
               
                 300 
                 306 
                 305 
                 ANAVSES 
               
               
                 1361 
                 1368 
                 1364 
                 LKSFSTAQ 
               
               
                   
               
            
           
           
               
               
            
               
                 73.  Aspergillus nidulans  AN7465.2 
                   
               
               
                 MFYSETLLSKTGPLARVWLSANLERKLSKSHILQSDIESSVSAIVDQGQAPMALRLSGQLLLGVVRIYSRKA 
               
               
                   
               
               
                 RYLLDDCNEALMKIKMAFRLTNNNDLTTSAVVAPGGITLPDVLTEADLFMNLDSSLLIPQPLSLEPEGKRPG 
               
               
                   
               
               
                 PSMDFGSQLFPDTGLRRSASQEPALLEDPGDLQLNLGLDDETNLSFSHDFSMEVGRDAPAPRPMEEDNFSDA 
               
               
                   
               
               
                 GKVIDVGDLGLNLGEDDTPLDAVNFDANEDNFLPLDEPMDLGDDTVVADGNDERFERESTLTEVSEDMIERL 
               
               
                   
               
               
                 NTEHEGDYMHDEEQDDETIQHAQRAKRRKQLPTIELDEAVEFKGNSYFRIQQEQLSETLKPASFLPRDPVLL 
               
               
                   
               
               
                 TLMNMQKNGDFVSNVMGGGRGRGWAPEIRDLLSFDTVRKAGELKRKRDSGISDMDVDAAAAPALEIEEEAIV 
               
               
                   
               
               
                 PVDEGVGMESTLHQRSEIDFPGDEEDHLRLSDDEGAQQPLEDFDDTITPVDSALVSVGTKRAVHVLRDCLGN 
               
               
                   
               
               
                 AEQKKAVKFQDLLPEKKATRADATKMFFEVLVLATKDAVQVEQRSNTVGGPIKISGKRSLWGQWAEEDATGE 
               
               
                   
               
               
                 VSQAQVAA 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 EGAQQPLEDFDDTITP 
                 466 
                 0.91 
               
               
                 1 
                 DDTPLDAVNFDANEDN 
                 232 
                 0.91 
               
               
                 2 
                 RDSGISDMDVDAAAAP 
                 407 
                 0.90 
               
               
                 2 
                 DETIQHAQRAKRRKQL 
                 304 
                 0.90 
               
               
                 3 
                 APEIRDLLSFDTVRKA 
                 385 
                 0.89 
               
               
                 3 
                 GRDAPAPRPMEEDNFS 
                 199 
                 0.89 
               
               
                 4 
                 TVVADGNDERFEREST 
                 261 
                 0.88 
               
               
                 5 
                 PRPMEEDNFSDAGKVI 
                 205 
                 0.87 
               
               
                 5 
                 PDVLTEADLFMNLDSS 
                 112 
                 0.87 
               
               
                 6 
                 FVSNVMGGGRGRGWAP 
                 371 
                 0.86 
               
               
                 7 
                 RSEIDFPGDEEDHLRL 
                 447 
                 0.85 
               
               
                 7 
                 IVPVDEGVGMESTLHQ 
                 431 
                 0.85 
               
               
                 7 
                 TIELDEAVEFKGNSYF 
                 321 
                 0.85 
               
               
                 7 
                 TEHEGDYMHDEEQDDE 
                 290 
                 0.85 
               
               
                 7 
                 MDLGDDTVVADGNDER 
                 255 
                 0.85 
               
               
                 7 
                 SDAGKVIDVGDLGLNL 
                 214 
                 0.85 
               
               
                 7 
                 QLFPDTGLRRSASQEP 
                 152 
                 0.85 
               
               
                 7 
                 PEGKRPGPSMDFGSQL 
                 138 
                 0.85 
               
               
                 8 
                 GVVRIYSRKARYLLDD 
                 63 
                 0.83 
               
               
                 9 
                 AVHVLRDCLGNAEQKK 
                 494 
                 0.82 
               
               
                 9 
                 ARVWLSANLERKLSKS 
                 15 
                 0.82 
               
               
                 10 
                 KIKMAFRLTNNNDLTT 
                 85 
                 0.81 
               
               
                 10 
                 VGMESTLHQRSEIDFP 
                 438 
                 0.81 
               
               
                 10 
                 RKAGELKRKRDSGISD 
                 398 
                 0.81 
               
               
                 11 
                 SETLLSKTGPLARVWL 
                 4 
                 0.80 
               
               
                 12 
                 CNEALMKIKMAFRLTN 
                 79 
                 0.78 
               
               
                 12 
                 QWAEEDATGEVSQAQV 
                 567 
                 0.78 
               
               
                 13 
                 QVEQRSNTVGGPIKIS 
                 544 
                 0.77 
               
               
                 13 
                 NAEQKKAVKFQDLLPE 
                 504 
                 0.77 
               
               
                 13 
                 STLTEVSEDMIERLNT 
                 275 
                 0.77 
               
               
                 14 
                 GPIKISGKRSLWGQWA 
                 554 
                 0.76 
               
               
                 14 
                 SAIVDQGQAPMALRLS 
                 42 
                 0.76 
               
               
                 14 
                 GLRRSASQEPALLEDP 
                 158 
                 0.76 
               
               
                 15 
                 VSVGTKRAVHVLRDCL 
                 487 
                 0.75 
               
               
                 15 
                 DEEDHLRLSDDEGAQQ 
                 455 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 51 
                 82 
                 62 
                 PMALRLSGQLLLGVVRIYSRKARYLLDDCNEA 
               
               
                 531 
                 546 
                 534 
                 FFEVLVLATKDAVQVE 
               
               
                 479 
                 504 
                 498 
                 ITPVDSALVSVGTKRAVHVLRDCLGN 
               
               
                 126 
                 137 
                 131 
                 SSLLIPQPLSLE 
               
               
                 38 
                 48 
                 42 
                 ESSVSAIVDQG 
               
               
                 344 
                 362 
                 359 
                 SETLKPASFLPRDPVLLTL 
               
               
                 576 
                 581 
                 580 
                 EVSQAQ 
               
               
                 100 
                 109 
                 101 
                 TSAVVAPGGI 
               
               
                 111 
                 118 
                 112 
                 LPDVLTEA 
               
               
                 429 
                 437 
                 435 
                 EAIVPVDEG 
               
               
                 508 
                 519 
                 514 
                 KKAVKFQDLLPE 
               
               
                 14 
                 22 
                 16 
                 LARVWLSAN 
               
               
                 216 
                 228 
                 222 
                 AGKVIDVGDLGLN 
               
               
                 388 
                 397 
                 394 
                 IRDLLSFDTV 
               
               
                 28 
                 36 
                 30 
                 SKSHILQSD 
               
               
                 175 
                 181 
                 179 
                 DLQLNLG 
               
               
                 417 
                 425 
                 421 
                 DAAAAPALE 
               
               
                 259 
                 265 
                 260 
                 DDTVVAD 
               
               
                 4 
                 12 
                 5 
                 SETLLSKTG 
               
               
                 165 
                 173 
                 167 
                 QEPALLEDP 
               
               
                 236 
                 241 
                 238 
                 LDAVNF 
               
               
                 553 
                 558 
                 555 
                 GGPIKI 
               
               
                 151 
                 156 
                 152 
                 SQLFPD 
               
               
                 336 
                 342 
                 337 
                 FRIQQEQ 
               
               
                   
               
            
           
           
               
               
            
               
                 74.  Aspergillus nidulans  AN4541.2 
                   
               
               
                 MSLHARLRPLPRRLATQPPSESAAPTPHFEDPPDGANAEDDAEDLFSSFLPHLFPDDAPQFHGDPGQYLLYS 
               
               
                   
               
               
                 SPRYGELQIMVPSYPSQSQSGARSKEIAEGLPRSDGQVNQVEEGRKLFAHFLWSAAMVVAEGLEQADTESGG 
               
               
                   
               
               
                 SEAEFWKVQNEKVLELGAGAGLPSIVSALANASMVTITDHPSSPALGPAGAIASNVKHNLSSSTSIVDIRPH 
               
               
                   
               
               
                 EWGTTLTTDPWALSNKGSYTRIIAADCYWMRSQHENLVRTMKWFLAPEGKIWVVAGFHTGREIVAGFFETAV 
               
               
                   
               
               
                 SLGLKIESIYERDLNSSAEEGGEVRRAWVSFREGEGPENRRRWCVVAVLGHAPAAAGTGADA 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 GEVRRAWVSFREGEGP 
                 310 
                 0.94 
               
               
                 2 
                 PHEWGTTLTTDPWALS 
                 215 
                 0.91 
               
               
                 2 
                 PPSESAAPTPHFEDPP 
                 18 
                 0.91 
               
               
                 3 
                 TPHFEDPPDGANAEDD 
                 26 
                 0.90 
               
               
                 4 
                 TESGGSEAEFWKVQNE 
                 140 
                 0.89 
               
               
                 5 
                 KEIAEGLPRSDGQVNQ 
                 97 
                 0.88 
               
               
                 5 
                 GLKIESIYERDLNSSA 
                 291 
                 0.88 
               
               
                 5 
                 MVTITDHPSSPALGPA 
                 178 
                 0.88 
               
               
                 6 
                 STSIVDIRPHEWGTTL 
                 207 
                 0.87 
               
               
                 6 
                 EGLEQADTESGGSEAE 
                 133 
                 0.87 
               
               
                 7 
                 SFREGEGPENRRRWCV 
                 318 
                 0.85 
               
               
                 7 
                 SSAEEGGEVRRAWVSF 
                 304 
                 0.85 
               
               
                 8 
                 AVLGHAPAAAGTGADA 
                 335 
                 0.83 
               
               
                 9 
                 HPSSPALGPAGAIASN 
                 184 
                 0.82 
               
               
                 9 
                 LPSIVSALANASMVTI 
                 166 
                 0.82 
               
               
                 9 
                 HFLWSAAMVVAEGLEQ 
                 122 
                 0.82 
               
               
                 10 
                 PQFHGDPGQYLLYSSP 
                 59 
                 0.80 
               
               
                 11 
                 IMVPSYPSQSQSGARS 
                 81 
                 0.78 
               
               
                 11 
                 DCYWMRSQHENLVRTM 
                 242 
                 0.78 
               
               
                 11 
                 AGAIASNVKHNLSSST 
                 193 
                 0.78 
               
               
                 12 
                 HLFPDDAPQFHGDPGQ 
                 52 
                 0.77 
               
               
                 13 
                 LHARLRPLFRRLATQP 
                 3 
                 0.76 
               
               
                 13 
                 TMKWFLAPEGKIWVVA 
                 256 
                 0.76 
               
               
                 14 
                 QYLLYSSPRYGELQIM 
                 67 
                 0.75 
               
               
                 14 
                 TGREIVAGFFETAVSL 
                 275 
                 0.75 
               
               
                 14 
                 RRLATQPPSESAAPTP 
                 12 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 330 
                 343 
                 334 
                 RWCVVAVLGHAPAA 
               
               
                 163 
                 205 
                 169 
                 GAGLPSIVSALANASMVTITDHPSSPALGPAGAIASN 
               
               
                   
                   
                   
                 VKHNLS 
               
               
                 44 
                 62 
                 52 
                 DLFSSFLPHLFPDDAPQFH 
               
               
                 66 
                 74 
                 71 
                 GQYLLYSSP 
               
               
                 236 
                 246 
                 241 
                 TRIIAADCYWM 
               
               
                 285 
                 297 
                 291 
                 ETAVSLGLKIESI 
               
               
                 266 
                 273 
                 270 
                 KIWVVAGF 
               
               
                 119 
                 134 
                 129 
                 LFAHFLWSAAMVVAEG 
               
               
                 76 
                 91 
                 86 
                 YGELQIMVPSYPSQSQ 
               
               
                 154 
                 161 
                 159 
                 NEKVLELG 
               
               
                 207 
                 214 
                 213 
                 STSIVDIR 
               
               
                 277 
                 283 
                 281 
                 REIVAGF 
               
               
                 4 
                 17 
                 6 
                 HARLRPLPRRLATQ 
               
               
                   
               
            
           
           
               
               
            
               
                 75.  Aspergillus nidulans  AN3628.2 
                   
               
               
                 MPQQLSSKDASLFRQVVRHYENKQYKKGIKTADQVLRKNPNHGDTLAMKALIMSNQGEQQEAFALAKEALKN 
               
               
                   
               
               
                 DMKSHICWHVYGLLYRAEKNYEEAIKAYRFALRIEPDSQPIQRDLALLQMQMRDYQGYIQSRSTMLQAPGF 
               
               
                   
               
               
                 RQNWTALAIAHHLSGDLEEAEKVLTTYEETLKTPPPLSDMEHSEATLYKNMIIAESGNIQKALEHLESVGHR 
               
               
                   
               
               
                 CSDVLAVMEMKADYLLRLDKKEEAAAAYTALLERNSENSLYYDGLIKAKGISSDDHKALKALYDSWAEKYPR 
               
               
                   
               
               
                 GDAPRRIPLDFLEGDDFKQAADAYLQRMLKKGVPSLFANIKLLYTNSSKRDTVQELVEGYVSNPPANGAADG 
               
               
                   
               
               
                 SENTEFLSSAYYFLAQHYNYHLSRDLSKALQNVDKALELSPKAVEYQMTKARIWKHYGNLEKAAEEMENARK 
               
               
                   
               
               
                 MDEKDRHINSKAAKYQLRNNNNDKALDKMSKFTRNETVGGALGDLHEMQCVWYLTEDGEAYLRQKKLGLALK 
               
               
                   
               
               
                 RFHAVYNIFDVWHEDQFDFHSFSLRKGMIRAYVDMVRWEDRLREHPFYTRAALSAIKAYILLHDQPDLAHGP 
               
               
                   
               
               
                 LPEINGADGDDAERKKALKKAKKEQQRLEKLEQEKREAARKAAANPKSLDGEVKKEDPDPLGNKLAQTQEPL 
               
               
                   
               
               
                 KEALKFLTPLLEHSPKNIEAQCLGFEVHLRRGKYALALKCLAAAHSIDASNPTLHVQLLQFRQALNKLYEPL 
               
               
                   
               
               
                 PPQVAEVVDSEFEALLPKAQNLEEWNKSFLSAHKDSIPHKYAYLTCQQLLKPESKSENEKELAATLDAGIMS 
               
               
                   
               
               
                 LETALAGLDLLGEWGSDKAAKTAYAEKASSKWPESTAFRVN 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 KGMIRAYVDMVRWEDR 
                 530 
                 0.94 
               
               
                 2 
                 STMLQARPGFRQNWTA 
                 135 
                 0.92 
               
               
                 3 
                 LPEINGADGDDAERKK 
                 577 
                 0.89 
               
               
                 3 
                 DSWAEKYPRGDAPRRI 
                 280 
                 0.89 
               
               
                 3 
                 HHLSGDLEEAEKVLTT 
                 155 
                 0.89 
               
               
                 4 
                 HKALKALYDSWAEKYP 
                 272 
                 0.88 
               
               
                 5 
                 EGYVSNPPANGAADGS 
                 346 
                 0.86 
               
               
                 5 
                 DAPRRIPLDFLEGDDF 
                 290 
                 0.86 
               
               
                 5 
                 YKKGIKTADQVLRKNP 
                 25 
                 0.86 
               
               
                 6 
                 AQTQEPLKEALKFLTP 
                 642 
                 0.85 
               
               
                 6 
                 MVRWEDRLREHPFYTR 
                 539 
                 0.85 
               
               
                 6 
                 KARIWKHYGNLEKAAE 
                 410 
                 0.85 
               
               
                 6 
                 AQHYNYHLSRDLSKAL 
                 375 
                 0.85 
               
               
                 6 
                 RDTVQELVEGYVSNPP 
                 338 
                 0.85 
               
               
                 7 
                 YEEAIKAYRFALRIEP 
                 93 
                 0.84 
               
               
                 7 
                 AAAAYTALLERNSENS 
                 240 
                 0.84 
               
               
                 7 
                 MRDYQGYIQSRSTMLQ 
                 124 
                 0.84 
               
               
                 8 
                 KSHICWHVYGLLYRAE 
                 75 
                 0.83 
               
               
                 8 
                 EVKKEDPDPLGNKLAQ 
                 628 
                 0.83 
               
               
                 8 
                 NSKAAKYQLRNNNNDK 
                 441 
                 0.83 
               
               
                 8 
                 QVLRKNPNHGDTLAMK 
                 34 
                 0.83 
               
               
                 8 
                 GISSDDHKALKALYDS 
                 266 
                 0.83 
               
               
                 8 
                 PLSDMEHSEATLYKNM 
                 180 
                 0.83 
               
               
                 9 
                 DAGIMSLETALAGLDL 
                 787 
                 0.82 
               
               
                 9 
                 SAHKDSIPHKYAYLTC 
                 751 
                 0.82 
               
               
                 9 
                 KKLGLALKRFHAVYNI 
                 497 
                 0.82 
               
               
                 9 
                 ARKMDEKDRHINSKAA 
                 430 
                 0.82 
               
               
                 9 
                 AEKVLTTYEETLKTPP 
                 164 
                 0.82 
               
               
                 10 
                 IPHKYAYLTCQQLLKP 
                 757 
                 0.81 
               
               
                 11 
                 PDLAHGPLPEINGADG 
                 570 
                 0.80 
               
               
                 11 
                 QGEQQEAFALAKEALK 
                 56 
                 0.80 
               
               
                 11 
                 GNLEKAAEEMENARKM 
                 418 
                 0.80 
               
               
                 11 
                 AVEYQMTKARIWKHYG 
                 403 
                 0.80 
               
               
                 12 
                 TEDGEAYLRQKKLGLA 
                 487 
                 0.79 
               
               
                 12 
                 GGALGDLHEMQCVWYL 
                 471 
                 0.79 
               
               
                 12 
                 SGNIQKALEHLESVGH 
                 200 
                 0.79 
               
               
                 12 
                 ETLKTPPPLSDMEHSE 
                 173 
                 0.79 
               
               
                 13 
                 WGSDKAAKTAYAEKAS 
                 806 
                 0.78 
               
               
                 13 
                 VDSEFEALLPKAQNLE 
                 728 
                 0.78 
               
               
                 13 
                 QCVWYLTEDGEAYLRQ 
                 481 
                 0.78 
               
               
                 13 
                 ALRIEPDSQPIQRDLA 
                 103 
                 0.78 
               
               
                 14 
                 KAYILLHDQPDLAHGP 
                 561 
                 0.76 
               
               
                 14 
                 TEFLSSAYYFLAQHYN 
                 364 
                 0.76 
               
               
                 14 
                 HLESVGHRCSDVLAVM 
                 209 
                 0.76 
               
               
                 15 
                 QEKREAARKAAANPKS 
                 609 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 204 
                 224 
                 220 
                 QKALEHLESVGHRCSDVLAVM 
               
               
                 700 
                 711 
                 705 
                 PTLHVQLLQFRQ 
               
               
                 667 
                 695 
                 686 
                 EAQCLGFEVHLRRGKYALALKCLAAAHSI 
               
               
                 76 
                 88 
                 80 
                 SHICWHVYGLLYR 
               
               
                 713 
                 731 
                 725 
                 LNKLYEPLPPQVAEVVDSE 
               
               
                 749 
                 773 
                 767 
                 FLSAHKDSIPHKYAYLTCQQLLKPE 
               
               
                 479 
                 486 
                 484 
                 EMQCVWYL 
               
               
                 4 
                 20 
                 14 
                 QLSSKDASLFRQVVRHY 
               
               
                 150 
                 159 
                 154 
                 ALAIAHHLSG 
               
               
                 548 
                 580 
                 563 
                 EHPFYTRAALSAIKAYILLHDQPDLAHGPLPEI 
               
               
                 341 
                 352 
                 347 
                 VQELVEGYVSNP 
               
               
                 367 
                 407 
                 374 
                 LSSAYYFLAQHYNYHLSRDLSKALQNVDKALELSPKAVEYQ 
               
               
                 493 
                 516 
                 512 
                 YLRQKKLGLALKRFHAVYNIFDVW 
               
               
                 793 
                 803 
                 800 
                 LETALAGLDLL 
               
               
                 241 
                 247 
                 245 
                 AAAYTAL 
               
               
                 648 
                 661 
                 655 
                 LKEALKFLTPLLEH 
               
               
                 318 
                 334 
                 323 
                 KKGVPSLFANIKLLYTN 
               
               
                 229 
                 234 
                 231 
                 DYLLRL 
               
               
                 255 
                 265 
                 259 
                 SLYYDGLIKAK 
               
               
                 114 
                 122 
                 120 
                 QRDLALLQM 
               
               
                 272 
                 281 
                 276 
                 HKALKALYDS 
               
               
                 733 
                 739 
                 737 
                 EALLPKA 
               
               
                 534 
                 540 
                 537 
                 RAYVDMV 
               
               
                 294 
                 300 
                 297 
                 RIPLDFL 
               
               
                 48 
                 53 
                 49 
                 MKALIM 
               
               
                 308 
                 316 
                 310 
                 AADAYLQRM 
               
               
                 62 
                 68 
                 67 
                 AFALAKE 
               
               
                 96 
                 107 
                 103 
                 AIKAYRFALRIE 
               
               
                 522 
                 528 
                 526 
                 DFHSFSL 
               
               
                 32 
                 38 
                 33 
                 ADQVLRK 
               
               
                 164 
                 170 
                 168 
                 AEKVLTT 
               
               
                 128 
                 133 
                 130 
                 QGYIQS 
               
               
                 471 
                 477 
                 475 
                 GGALGDL 
               
               
                   
               
            
           
           
               
               
            
               
                 76.  Aspergillus nidulans  EAA58968 
                   
               
               
                 MARTQKNKNTSYHLGQLKAKLAKLKRELLTPSGGGGGGSGAGFDVARTGVASVGFIGFPSVGKSTLMSRLTG 
               
               
                   
               
               
                 QHSEAAAYEFTTLTTVPGQVLYNGAKIQILDLPGIIQGAKDGKGRGRQVIAVAKTCHLIFIVLDVNKPLVDK 
               
               
                   
               
               
                 KVIENELEGFGIRINKQPPNIMFKKKDKGGISITSTVPLTHIDNDEIKAVMSEYKISSADISIRCDATIDDL 
               
               
                   
               
               
                 IDVLEAKSRAYIPVVYALNKIDAITIEELDLLYRIPNAVPISSEHGWNIDELLEMMWEKLNLRRIYTKPKGK 
               
               
                   
               
               
                 APDYTAPVVLRANACTVEDFCNAIHRTIKDQFKQAIVYGRSVKHQPQRVGLTHELADEDIGSRPFCEAYGTI 
               
               
                   
               
               
                 GLTV 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 APDYTAPVVLRANACT 
                 289 
                 0.95 
               
               
                 2 
                 TPSGGGGGGSGAGFDV 
                 30 
                 0.92 
               
               
                 3 
                 GWNIDELLEMMWEKLN 
                 262 
                 0.91 
               
               
                 4 
                 LRRIYTKPKGKAPDYT 
                 278 
                 0.89 
               
               
                 4 
                 PGIIQGAKDGKGRGRQ 
                 105 
                 0.89 
               
               
                 5 
                 HELADEDIGSRPFCEA 
                 341 
                 0.88 
               
               
                 6 
                 EMMWEKLNLRRIYTKP 
                 270 
                 0.85 
               
               
                 6 
                 KVIENELEGFGIRINK 
                 145 
                 0.85 
               
               
                 7 
                 GISITSTVPLTHIDND 
                 174 
                 0.84 
               
               
                 8 
                 QHSEAAAYEFTTLTTV 
                 73 
                 0.82 
               
               
                 9 
                 TIEELDLLYRIPNAVP 
                 241 
                 0.80 
               
               
                 10 
                 GAKIQILDLPGIIQGA 
                 96 
                 0.78 
               
               
                 10 
                 ISSADISIRCDATIDD 
                 200 
                 0.78 
               
               
                 11 
                 VGFIGFPSVGKSTLMS 
                 53 
                 0.77 
               
               
                 11 
                 GGSGAGFDVARTGVAS 
                 37 
                 0.77 
               
               
                 12 
                 QLKAKLAKLKRELLTP 
                 16 
                 0.76 
               
               
                 12 
                 DGKGRGRQVIAVAKTC 
                 113 
                 0.76 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 119 
                 145 
                 131 
                 RQVIAVAKTCHLIFIVLDVNKPLVDKK 
               
               
                 225 
                 237 
                 231 
                 RAYIPVVYALNKI 
               
               
                 291 
                 314 
                 295 
                 DYTAPVVLRANACTVEDFCNAIHR 
               
               
                 85 
                 96 
                 91 
                 LTTVPGQVLYNG 
               
               
                 42 
                 64 
                 53 
                 GFDVARTGVASVGFIGFPSVGKS 
               
               
                 321 
                 342 
                 327 
                 KQAIVYGRSVKHQPQRVGLTHE 
               
               
                 214 
                 223 
                 219 
                 DDLIDVLEAK 
               
               
                 242 
                 259 
                 248 
                 IEELDLLYRIPNAVPISS 
               
               
                 177 
                 185 
                 183 
                 ITSTVPLTH 
               
               
                 99 
                 110 
                 102 
                 IQILDLPGIIQG 
               
               
                 11 
                 31 
                 14 
                 SYHLGQLKAKLAKLKRELLTP 
               
               
                 199 
                 212 
                 206 
                 KISSADISIRCDAT 
               
               
                 351 
                 357 
                 355 
                 RPFCEAY 
               
               
                 76 
                 83 
                 77 
                 EAAAYEFT 
               
               
                 191 
                 197 
                 197 
                 IKAVMSE 
               
               
                   
               
            
           
           
               
               
            
               
                 77.  Aspergillus nidulans  AN2960.2 
                   
               
               
                 MAPSIATSEHVDLRAPIKTLLKTNAGHNKENVIGYGETYKHADELKGTVKQPPASFPHYLPVWDNETERYPP 
               
               
                   
               
               
                 LQPFEHYDHGKDADPAFPDLFPKDASFHRDDLTPTIGSEVSGIQLSQLSKEGKDQLALFVAQRKVVAFRDQD 
               
               
                   
               
               
                 FAHLPIDKALEFGGYFGRHHIHQASGAPRGYPEIHLVHRGADDTSGADFLAQHTNSITWHSDVTFEVQPPGT 
               
               
                   
               
               
                 TFLYLLDGPTTGGDTLFADMAQAYKRLSPEFRKRLHGLKAVHSGVEQVNNSLNKGGIARRDPIMTEHPIVET 
               
               
                   
               
               
                 HPVTGEKALFVNAQFTRYIVGYKKEESDFLLKFLYDHIALSQDIQTRVRWRPGTVVVWDNRVACHSALFDWA 
               
               
                   
               
               
                 DGQRRHLARITPQAERPYETPFEG 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 TNSITWHSDVTFEVQP 
                 198 
                 0.94 
               
               
                 2 
                 PLQPFEHYDHGKDADP 
                 72 
                 0.93 
               
               
                 3 
                 RAPIKTLLKTNAGHNK 
                 14 
                 0.91 
               
               
                 4 
                 SQDIQTRVRWRPGTVV 
                 329 
                 0.90 
               
               
                 5 
                 APSIATSEHVDLRAPI 
                 2 
                 0.89 
               
               
                 5 
                 HLPIDKALEFGGYFGR 
                 147 
                 0.89 
               
               
                 6 
                 RRDPIMTEHPIVRTHP 
                 275 
                 0.88 
               
               
                 6 
                 LVHRGADDTSGADFLA 
                 180 
                 0.88 
               
               
                 7 
                 LPVWDNETERYPPLQP 
                 60 
                 0.87 
               
               
                 7 
                 IGYGETYKHADELKGT 
                 33 
                 0.87 
               
               
                 8 
                 YDHGKDADPAFPDLFP 
                 79 
                 0.85 
               
               
                 8 
                 KGTVKQPPASFPHYLP 
                 46 
                 0.85 
               
               
                 8 
                 RWRPGTVVVWDNRVAC 
                 337 
                 0.85 
               
               
                 8 
                 YIVGYKKEESDFLLKF 
                 306 
                 0.85 
               
               
                 9 
                 HLARITPQAERPYETP 
                 366 
                 0.84 
               
               
                 9 
                 HPVTGEKALFVNAQFT 
                 289 
                 0.84 
               
               
                 9 
                 VSGIQLSQLSKEGKDQ 
                 112 
                 0.84 
               
               
                 10 
                 TFEVQPPGTTFLYLLD 
                 208 
                 0.82 
               
               
                 10 
                 GYPEIHLVHRGADDTS 
                 174 
                 0.82 
               
               
                 11 
                 DLFPKDASFHRDDLTP 
                 91 
                 0.81 
               
               
                 11 
                 QAYKRLSPEFRKRLHG 
                 238 
                 0.81 
               
               
                 11 
                 HQASGAPRGYPEIHLV 
                 166 
                 0.81 
               
               
                 12 
                 HPIVRTHPVTGEKALF 
                 283 
                 0.80 
               
               
                 13 
                 NKGGIARRDPIMTEHP 
                 269 
                 0.79 
               
               
                 14 
                 FDWADGQRRHLARITP 
                 357 
                 0.77 
               
               
                 15 
                 NRVACHSALFDWADGQ 
                 348 
                 0.75 
               
               
                 15 
                 DGPTTGGDTLFADMAQ 
                 223 
                 0.75 
               
               
                 15 
                 TPTIGSEVSGIQLSQL 
                 105 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 341 
                 358 
                 353 
                 GTVVVWDNRVACHSALFD 
               
               
                 46 
                 63 
                 59 
                 KGTVKQPPASFPHYLPVW 
               
               
                 127 
                 141 
                 131 
                 QLALFVAQRKVVAFR 
               
               
                 316 
                 331 
                 320 
                 DFLLKFLYDHIALSQD 
               
               
                 175 
                 184 
                 178 
                 YPEIHLVHRG 
               
               
                 282 
                 294 
                 288 
                 EHPIVRTHPVTGE 
               
               
                 251 
                 265 
                 254 
                 LHGLKAVHSGVEQVN 
               
               
                 216 
                 224 
                 219 
                 TTFLYLLDG 
               
               
                 70 
                 79 
                 73 
                 YPPLQPFEHY 
               
               
                 109 
                 120 
                 118 
                 GSEVSGIQLSQL 
               
               
                 204 
                 214 
                 210 
                 HSDVTFEVQPP 
               
               
                 296 
                 302 
                 300 
                 ALFVNAQ 
               
               
                 4 
                 20 
                 14 
                 SIATSEHVDLRAPIKTL 
               
               
                 145 
                 153 
                 147 
                 FAHLPIDKA 
               
               
                 304 
                 310 
                 309 
                 TRYIVGY 
               
               
                 161 
                 169 
                 166 
                 GRHHIHQAS 
               
               
                 87 
                 97 
                 90 
                 PAFPDLFPKDA 
               
               
                 191 
                 198 
                 194 
                 ADFLAQHT 
               
               
                 365 
                 371 
                 369 
                 RHLARIT 
               
               
                 240 
                 246 
                 240 
                 YKRLSPE 
               
               
                   
               
            
           
           
               
               
            
               
                 78.  Aspergillus nidulans  AN5922.2 
                   
               
               
                 MGQYSSTQREHRHQFPTESPLPRQRSHSRNRDEDMNNGQNPERAGAFSPQAGQEIDNNDVQMTHSTETNFLV 
               
               
                   
               
               
                 DPLQSLISHSSMLGSEEQMGNTQDETGSQDDASQQDYQSALFARVARRHSTMSRLGSRILPNSVIRGLLNSE 
               
               
                   
               
               
                 EETPAEGHAHRHGVVSRTIPRSEVNQSSARFSPFASLSSRGGSRRRSLRGPYFIPRSDAAINNNGFLGTPSG 
               
               
                   
               
               
                 PSTDGSAEPGWGWRRSLRIRRVGRVGHSLPTPIAQMFGPPSSDSTPAQDTENPPYSFHNSDPFSFIPHPGPL 
               
               
                   
               
               
                 DTQMDFDTPHELNSVEPALADSQPASPMLTSQSQSSTRHFPSLLRARPPRALRREEQTPLSRILQLAATAIA 
               
               
                   
               
               
                 TQLSGGAGPALPNIPSLGNDGFDGSLESFIQSLRNATSGQPSSGDSNNNSEDERPPGPVNFMRVFRFASDN 
               
               
                   
               
               
                 SRSSDAPNRASTDQNNAVSNGDNMETDHHAEGQEGRTVTLVVIGVRSVPSGNGPAGDQQTAGLPGLDFLRLP 
               
               
                   
               
               
                 FFPPGTLSPRPGPRPETTTSDHSASSSAPPANVDGSIQPGSPNVPRRLSDVGSRGTLSSLPSVVSESPPGPH 
               
               
                   
               
               
                 PPPSTPAEPGLSAVSSGASTPSRRLSTTSAVSPNIMHQLNESRPSHPTVDNRDESLPHNTTHQRRRSDSEFA 
               
               
                   
               
               
                 RHREQLGSGAARRNGVVEPDNHNAAPGRSWLIYVVGTNLSENHPAFAAPSLFTDNPTYEDMVLLSSLLGPVK 
               
               
                   
               
               
                 PPVATQEDLISAGGLYRVVKCGDSMSAAAVDGTRTIQISEGERCLICLSEYEVAEELRQLTKCEHLYHRDCI 
               
               
                   
               
               
                 DQHGAFPSSFTISSHLSLFASDIHCCIATFWFWLWGSRKIMKFITYRIKVDYLPTSHTTFITESSKQETKEQ 
               
               
                   
               
               
                 QMDSIRLTVLISGSGTNLQAVIDDTTLPAKIVRVISNRKDAFGLERARRANIPTQYHNLVKYKKQHPATPEG 
               
               
                   
               
               
                 VQRAREEYDAELARLVLEDKPDLVACLGFMHVLSEGFLGPLEAKGVRIVNLHPALPGEFNGANAERAHQAW 
               
               
                   
               
               
                 LDGKIERTGVMIHNVISEVDMGKPILVKEIPFVKGADEDLHAFEQKVHEIEWKVVIEGLQKTIEEIRTTKS 
               
               
                   
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Rank 
                 Sequence 
                 Start position 
                 Score 
               
               
                   
               
               
                 1 
                 EGVQRAREEYDAELAR 
                 935 
                 0.97 
               
               
                 2 
                 SHSRNRDEDMNNGQNP 
                 26 
                 0.95 
               
               
                 3 
                 PGTLSPRPGPRPETTT 
                 508 
                 0.94 
               
               
                 4 
                 AFSPQAGQEIDNNDVQ 
                 46 
                 0.93 
               
               
                 4 
                 PPSSDSTPAQDTENPP 
                 255 
                 0.93 
               
               
                 4 
                 DGKIERTGVMIHNVIS 
                 1010 
                 0.93 
               
               
                 5 
                 GSEEQMGNTQDETGSQ 
                 86 
                 0.92 
               
               
                 6 
                 HPTVDNRDESLPHNTT 
                 622 
                 0.91 
               
               
                 6 
                 HPPPSTPAEPGLSAVS 
                 576 
                 0.91 
               
               
                 6 
                 VVSESPPGPHPPPSTP 
                 567 
                 0.91 
               
               
                 6 
                 SRSSDAPNRASTDQNN 
                 433 
                 0.91 
               
               
                 7 
                 SRKIMKFITYRIKVDY 
                 829 
                 0.90 
               
               
                 7 
                 AQDTENPPYSFHNSDP 
                 263 
                 0.90 
               
               
                 8 
                 ACLGFMHVLSEGFLGP 
                 961 
                 0.89 
               
               
                 8 
                 GQEIDNNDVQMTHSTE 
                 52 
                 0.89 
               
               
                 8 
                 RGPYFIPRSDAAINNN 
                 193 
                 0.89 
               
               
                 9 
                 TRTIQISEGERCLICL 
                 753 
                 0.88 
               
               
                 9 
                 NESRPSHPTVDNRDES 
                 616 
                 0.88 
               
               
                 9 
                 SIQPGSPNVPRRLSDV 
                 540 
                 0.88 
               
               
                 9 
                 PGPRPETTTSDHSASS 
                 515 
                 0.88 
               
               
                 9 
                 NATSGQPSSGDSNNNS 
                 395 
                 0.88 
               
               
                 9 
                 PAEGHAHRHGVVSRTI 
                 148 
                 0.88 
               
               
                 10 
                 TGSQDDASQQDYQSAL 
                 98 
                 0.87 
               
               
                 10 
                 DYLPTSHTTFITESSK 
                 843 
                 0.87 
               
               
                 10 
                 LDTQMDFDTPHELNSV 
                 288 
                 0.87 
               
               
                 11 
                 EDLISAGGLYRVVKCG 
                 727 
                 0.86 
               
               
                 11 
                 SWLIYVVGTNLSENHP 
                 677 
                 0.86 
               
               
                 11 
                 NMETDHHAEGQEGRTV 
                 455 
                 0.86 
               
               
                 11 
                 TPIAQMFGPPSSDSTP 
                 247 
                 0.86 
               
               
                 11 
                 GQYSSTQREHRHQFPT 
                 2 
                 0.86 
               
               
                 12 
                 TVLISGSGTNLQAVID 
                 872 
                 0.85 
               
               
                 12 
                 QLTKCEHLYHRDCIDQ 
                 779 
                 0.85 
               
               
                 12 
                 RHGVVSRTIPRSEVNQ 
                 155 
                 0.85 
               
               
                 13 
                 QAVIDDTTLPAKIVRV 
                 883 
                 0.84 
               
               
                 13 
                 AVSSGASTPSRRLSTT 
                 589 
                 0.84 
               
               
                 13 
                 RRHSTMSRLGSRILPN 
                 119 
                 0.84 
               
               
                 14 
                 LGPLEAKGVRIVNLHP 
                 974 
                 0.83 
               
               
                 14 
                 CGDSMSAAAVDGTRTI 
                 741 
                 0.83 
               
               
                 14 
                 DVQMTHSTETNFLVDP 
                 59 
                 0.83 
               
               
                 14 
                 RREEQTPLSRILQLAA 
                 341 
                 0.83 
               
               
                 15 
                 HQRRRSDSEFARHREQ 
                 638 
                 0.82 
               
               
                 15 
                 SGNGPAGDQQTAGLPG 
                 482 
                 0.82 
               
               
                 15 
                 SFHNSDPFSFIPHPGP 
                 272 
                 0.82 
               
               
                 15 
                 PSGPSTDGSAEPGWGW 
                 214 
                 0.82 
               
               
                 15 
                 VHEIEWKVVIEGLQKT 
                 1055 
                 0.82 
               
               
                 16 
                 SNRKDAFGLERARRAN 
                 900 
                 0.81 
               
               
                 16 
                 TYRIKVDYLPTSHTTF 
                 837 
                 0.81 
               
               
                 16 
                 PSSGDSNNNSEDERPP 
                 401 
                 0.81 
               
               
                 17 
                 RDCIDQHGAFPSSFTI 
                 789 
                 0.80 
               
               
                 17 
                 EQLGSGAARRNGVVEP 
                 652 
                 0.80 
               
               
                 17 
                 ESFIQSLRNATSGQPS 
                 387 
                 0.80 
               
               
                 17 
                 SLSSRGGSRRRSLRGP 
                 180 
                 0.80 
               
               
                 17 
                 HQFPTESPLPRQRSHS 
                 13 
                 0.80 
               
               
                 18 
                 IPTQYHNLVKYKKQHP 
                 916 
                 0.79 
               
               
                 18 
                 HSASSSAPPANVDGSI 
                 526 
                 0.79 
               
               
                 18 
                 GPVNFMRVFRFANSDN 
                 417 
                 0.79 
               
               
                 18 
                 PNSVIRGLLNSEEETP 
                 133 
                 0.79 
               
               
                 19 
                 GNTQDETGSQDDASQQ 
                 92 
                 0.78 
               
               
                 19 
                 DESLPHNTTHQRRRSD 
                 629 
                 0.78 
               
               
                 19 
                 AATAIATQLSGGAGPA 
                 355 
                 0.78 
               
               
                 19 
                 SEVNQSSARFSPFASL 
                 166 
                 0.78 
               
               
                 19 
                 KPILVKEIPFVKGADE 
                 1031 
                 0.78 
               
               
                 20 
                 NPTYEDMVLLSSLLGP 
                 703 
                 0.77 
               
               
                 21 
                 HAEGQEGRTVTLVVIG 
                 461 
                 0.76 
               
               
                 21 
                 SEDERPPGPVNFMRVF 
                 410 
                 0.76 
               
               
                 21 
                 LRARPPRALRREEQTP 
                 332 
                 0.76 
               
               
                 21 
                 EDMNNGQNPERAGAFS 
                 33 
                 0.76 
               
               
                 21 
                 SQSQSSTRHFPSLLRA 
                 319 
                 0.76 
               
               
                 21 
                 PGWGWRRSLRIRRVGR 
                 225 
                 0.76 
               
               
                 22 
                 SGGAGPALPNIPSLGN 
                 364 
                 0.75 
               
               
                 22 
                 RVGRVGHSLPTPIAQM 
                 237 
                 0.75 
               
               
                   
               
            
           
           
               
               
               
               
            
               
                 Start 
                 End 
                 Max_score_pos 
                 Sequence 
               
               
                   
               
               
                 707 
                 742 
                 713 
                 EDMVLLSSLLGPVKPPVATQEDLISAGGLYRVVKCG 
               
               
                 469 
                 480 
                 472 
                 TVTLVVIGVRSV 
               
               
                 761 
                 777 
                 766 
                 GERCLICLSEYEVAEEL 
               
               
                 946 
                 977 
                 962 
                 AELARLVLEDKPDLVACLGFMHVLSEGFLGPL 
               
               
                 676 
                 686 
                 680 
                 RSWLIYVVGTN 
               
               
                 779 
                 824 
                 818 
                 QLTKCEHLYHRDCIDQHGAFPSSFTISSHLSLFASDIHC 
               
               
                   
                   
                   
                 CIATFWF 
               
               
                 561 
                 571 
                 565 
                 LSSLPSVVSES 
               
               
                 870 
                 877 
                 872 
                 RLTVLISG 
               
               
                 892 
                 899 
                 896 
                 PAKIVRVI 
               
               
                 979 
                 992 
                 985 
                 AKGVRIVNLHPALP 
               
               
                 69 
                 84 
                 73 
                 NFLVDPLQSLISHSSM 
               
               
                 1047 
                 1066 
                 1065 
                 DLHAFEQKVHEIEWKVVIEG 
               
               
                 1032 
                 1043 
                 1038 
                 PILVKEIPFVKG 
               
               
                 837 
                 848 
                 843 
                 TYRIKVDYLPTS 
               
               
                 348 
                 362 
                 351 
                 LSRILQLAATAIATQ 
               
               
                 128 
                 140 
                 138 
                 GSRILPNSVIRGL 
               
               
                 107 
                 120 
                 115 
                 QDYQSALFARVARR 
               
               
                 154 
                 162 
                 156 
                 HRHGVVSRT 
               
               
                 1018 
                 1026 
                 1021 
                 VMIHNVISE 
               
               
                 917 
                 932 
                 923 
                 PTQYHNLVKYKKQHPA 
               
               
                 493 
                 514 
                 503 
                 AGLPGLDFLRLPFFPPGTLSPR 
               
               
                 300 
                 320 
                 305 
                 LNSVEPALADSQPASPMLTSQ 
               
               
                 584 
                 593 
                 588 
                 EPGLSAVSSG 
               
               
                 325 
                 335 
                 330 
                 TRHFPSLLRAR 
               
               
                 692 
                 699 
                 697 
                 PAFAAPSL 
               
               
                 238 
                 252 
                 244 
                 VGRVGHSLPTPIAQM 
               
               
                 882 
                 889 
                 885 
                 LQAVIDDT 
               
               
                 173 
                 182 
                 178 
                 ARFSPFASLS 
               
               
                 279 
                 288 
                 281 
                 FSFIPHPGPL 
               
               
                 368 
                 375 
                 374 
                 GPALPNIP 
               
               
                 603 
                 610 
                 604 
                 TTSAVSPN 
               
               
                 193 
                 202 
                 195 
                 RGPYFIPRSD 
               
               
                 662 
                 667 
                 667 
                 NGVVEP 
               
               
                 527 
                 540 
                 534 
                 SASSSAPPANVDGS 
               
               
                 387 
                 393 
                 391 
                 ESFIQSL 
               
               
                 545 
                 555 
                 551 
                 SPNVPRRLSDV 
               
               
                 573 
                 582 
                 575 
                 PGPHPPPSTP 
               
               
                 16 
                 24 
                 18 
                 PTESPLPRQ 
               
               
                   
               
            
           
         
       
     
     Patients with candidiasis mounted significant IgG titers against  Candida  proteins within 2 weeks of their diagnoses, whereas IgM titers did not differ from those of controls. This finding suggests that systemic candidiasis is well-established prior to the point at which the disease is diagnosed by current methods. Alternatively, a patient might have ongoing, low-level systemic exposure to  Candida  that predisposes them to systemic candidiasis. 
     Four  C. albicans  proteins (Set1p, Rbt4p, Met6p and Bgl2p) may serve as diagnostic targets, for serologic or antigen detection tests. Antibody profiling against  candida  proteins such as these may identify patients at high-risk to develop candidiasis, and could be a tool for targeted, pre-emptive therapy. 
     Antibody responses among patients with candidiasis due to other  Candida  spp. are being carried out. Trends of immunoglobulin responses during the course of candidiasis are being determined. 
     Example 2  
     Expression and Purification of Antigens  
     Fifteen antigens from 12 distinct proteins were expressed as 6× His-tagged polypeptides in  E. coli  and purified from cell-free supernatants by chromatography on Ni 2+ -NTA-agarose. Nine of the purified recombinant antigens were full-length (Table 9). MET1, PGK2 and MUC2 could not be efficiently expressed as full-length proteins, and were instead purified as two fragments (MET6-F1 and -F2; PGK1-F1 and -F2, and MUC1-F1 and -F2). The purified antigens appeared as single bands of expected sizes by SDS-PAGE and were detected by probing with anti-His antibodies (data not shown). 
     Example 3  
     Recognition of Antigens by Sera from Patients with  Candidiasis and Un-Infected Controls  
     Sera from the patients with candidiasis and un-infected controls were tested against the 15 recombinant antigens using ELISA. The sera from 2 patients (one with systemic candidiasis and one control) were sufficient to test against only 14 antigens (all except PGK1). As anticipated, the IgM and IgG titers in the sera of the 8 premature or newborn infants were consistently low (at or below the control levels) against each of the recombinant antigens. As such, these sera were excluded from further data analysis. 
     Overall, the IgG titers from the sera of patients enrolled in this study better differentiated patients with systemic candidiasis and controls than IgM ( FIGS. 3A and 3B ). For this reason, only IgG response was selected for further analysis. There were no significant differences in titers between immunocompromised hosts, burn victims and other patients with candidiasis, between patients infected with  C. albicans  vs. non- C. albicans  spp., or based on portal of entry. 
     Example 4  
     Identification of Antibody Responses that  Discriminate Patients with Systemic Candidiasis from Controls  
     For each of the antigens, cut-off antibody titers were assigned that best discriminated patients from controls. The sensitivity and specificity of the antibody responses against individual antigens in identifying patients with systemic candidiasis are presented in Table 12. 
     Having shown that IgG titers against specific antigens diagnosed systemic candidiasis with reasonable sensitivity and specificity, the inventors sought to develop a predictive model that considered antibody responses against a panel of antigens. Collinearity was assessed by determining the tolerance of each of the 15 predictor variables (i.e., antibodies to specific antigens) on the others. Since collinearity diagnostics revealed no collinearity problems, all 15 antigens were included in the analysis. 
     Backwards elimination and canonical correlation analyses were then used to identify variables that might best predict systemic candidiasis. The two methods demonstrated excellent overall agreement in identifying predictors likely to be significant. The rank order in which the predictor variables were identified using canonical correlation analysis is presented in Table 13. Based on these results, a panel of seven predictors (SET1, MUC1-2, FBA1, PGK1-F1, PGK1-F2, and BCL2 and ENO1) were selected for discriminant analysis. 
     Discriminant analysis of the full set of 15 predictors yielded an outcome classification error rate of 3.7% (3/82) (Table 14). Among the 82 patients and controls enrolled in the study, only 3 were classified incorrectly: one patient with systemic candidiasis was predicted to be a control, and 2 controls were predicted to have systemic candidiasis. The sensitivity and specificity of the panel of 15 predictors were 96.6% and 95.6%, respectively. Discriminant analysis of the panel of 7 predictors yielded identical results. Using classification tables generated for smaller subsets of predictors, the inventors identified a panel of 4 predictors (SET1, ENO1, MUC1-2 and PGK1-2) that performed as well as the larger panels (Table 14). Canonical discriminate analysis was applied to assign weights to each of the 4 variables in the prediction of systemic candidiasis; the strongest correlations were with SET1 (the standardized canonical coefficients for SET1, ENO1, MUC1-2 and PGK1-2 were 1.29, 0.91, −0.39 and −0.20, respectively). 
     Using regression analysis, it was confirmed that the panel of 4 predictors performed as well as the 15 predictors in diagnosing systemic candidiasis. The analysis of the 4 predictors yielded an R 2  of 0.69, which was not significantly different from the R 2  of 0.73 for the full model (F=0.98, p=0.47). 
     Example 5  
     Testing a Prediction Model for Systemic Candidiasis  
     Based on the data, the equation that best predicted systemic candidiasis was: prediction score=(0.10*SET1±0.07*ENO−0.04*MUC1-F2−0.02*PGK1-F2−0.12), where SET1, ENO, MUC1-F2 and PGK1-F2 denote the log 2  of the specific antibody titers in individual patients. A score &gt;0.5 for a given patient was predictive of systemic candidiasis. 
     To test the validity of this model, ELISAs were performed against the 15 recombinant antigens using sera that had been collected from 16 patients with systemic candidiasis and 16 un-infected controls prior to the present study. The panel of 4 predictors yielded sensitivity and specificity of 100% (16/16) and 87.5% (14/16), respectively. The only classification errors were two controls who were predicted to have systemic candidiasis. 
     To the inventors&#39; knowledge, this is the first study to demonstrate that antibody responses against a panel of  C. albicans  antigens can accurately diagnose systemic candidiasis. Serum IgG responses were measured against 15 recombinant  C. albicans  antigens by ELISA and derived a prediction model that identified patients with systemic candidiasis with an error rate of only 3.7%, sensitivity of 96.6% and specificity of 95.6%. The performance of the prediction model was superior to antibody detection against any individual antigen. Using backwards elimination and canonical correlation analyses, a subset of 4 antigens that performed as accurately as the full panel was identified. The inventors further confirmed the validity of the 4 antigen panel by testing sera that were different from those used to derive the prediction model. Given the limitations of current diagnostic tests, measuring antibody responses against a panel such as ours might represent a significant advance in the diagnosis of systematic candidiasis. 
     These data refute several of the major concerns about the limitations of antibody detection as a diagnostic tool. First, the inventors demonstrated that patients with systemic candidiasis exhibited significant IgG titers against a wide range of antigens at the time of positive blood cultures. This observation corroborates a number of reports documenting significant IgG titers against individual proteins like Eno1p, Hwp1p, mannan and CAGTA before or at the time of the first positive blood culture (Lain, A et al.  BMC Microbiol.,  2007; 7:35; Lain, A et al.  Clin Vaccine Immunol.,  2007; 14:318-9; Pazos, C et al.  Rev Iberoam Micol.,  2006; 23:209-15). Such findings are consistent with the fact that blood cultures are often not positive until relatively late in the disease course (Morris, A J et al.  J Clin Microbiol.,  1996; 34:1583-5; Garey, K W et al.  Clin Infect Dis.,  2006 Jul. 1; 43:25-3; Morrell, M et al.  Antimicrob Agents Chemother.,  2005; 49:3640-5). Alternatively, it is possible that invasive diseases like candidemia are preceded in at least some patients by low-level systemic exposure to  Candida  spp., perhaps reflecting “leakage” from mucosal sites of colonization. It is striking that IgG responses were superior to IgM in discriminating patients with systemic candidiasis from controls. In fact, the majority of studies to date have looked at IgG antibodies (Quindos, G et al.  Rev Iberoam Micol.,  2004; 21(1)). Studies of IgM responses have yielded conflicting results, with results superior to IgG against blastospore cytoplasm and mannan in one study and inferior against hyphal cell wall proteins in another (Gutierrez, J et al.  J Clin Microbiol.,  1993; 31:2550-2; Torres-Rodriguez, J M et al.  Mycoses.,  1997; 40:439-44). We hypothesize that the potent IgG responses in the present study are consistent with amnestic responses against tissue invasion by a commensal organism to which the host has already been exposed. 
     Second, the inventors showed that the sensitivity of antibody detection was not attenuated among patients who were significantly immunocompromised, including stem cell and solid organ transplant recipients, patients with hematologic malignancies and a high-dose steroid recipient with lupus. Again, this observation is consistent with numerous reports assessing antibody responses against individual antigens. Third, it was found that antibody responses to the recombinant  C. albicans  antigens included in the panel diagnosed patients infected with non- C. albicans  spp. as well as  C. albicans , which likely reflected the inclusion of conserved proteins like glycolytic enzymes, SET1 (a histone methyltransferase) and NOT5 (a component of the CCR-NOT global regulatory complex). Indeed, IgG responses against  C. albicans  enolase have been reported to be effective in identifying patients with candidemia caused by diverse  Candida  spp. (Lain, A et al.  BMC Microbial.,  2007; 7:35). Interestingly, a recent study showed that the detection of antibodies to HWP1, a protein produced exclusively during hyphal growth by  C. albicans , is also useful among patients infected with non- C. albicans  spp. (Lain, A et al.  BMC Microbial.,  2007; 7:35), suggesting that epitopes within non-conserved proteins might also elicit cross-reactive responses. 
     The sensitivities and specificities that were observed with individual proteins are within the ranges previously reported for antibody detection against a variety of antigens. Studies of IgG responses to enolase, for example, have yielded sensitivities of 50-92% and specificities of 78-95% (Quindos, Get al.  Rev Iberoam Micol.,  2004; 21(1); Lain, A et al.  Clin Vaccine Immunol.,  2007; 14:318-9; van Deventer, A J et al.  Microbial Immunol.,  1996; 40:125-31; Mitsutake, K et al.  J Clin Microbial.,  1996; 1918-21), and similar performances have been reported for tests against SAP (Na B K and Song C Y  Clin Diagn Lab Immunol.,  1999; 6:924-9; Yang Q et al.  Mycoses,  2007; 50:165-71), HWP1 (Lain, A et al.  Clin Vaccine Immunol.,  2007; 14:318-9), a 52 kDa metalloprotein (El Moudni, B et al.  Clin Diagn Lab Immunol.,  1998; 5:823-5), mannan (Sendid, B et al.  J Clin Microbial.,  1999; 37:1510-7; Yera, H et al.  Eur J Clin Microbial Infect Dis.,  2001; 20:864-70) and CTGTA (Quindos, G et al.  Rev Iberoam Micol.,  2004; 21(1); Lain, A et al.  BMC Microbial.,  2007; 7:35). In attempts to overcome the diagnostic limitations of existing antibody tests, investigators have used a number of them in combination with antigen and/or metabolite detection. In general, these strategies have improved the sensitivity and specificity of the individual tests, as well as resulted in earlier diagnoses of systemic candidiasis (Fisher, J F et al.  Am J Med Sci.,  1985; 290:135-42; Sendid, B et al.  J Clin Microbial.,  1999; 37:1510-7; Sendid, B et al.  J Med Microbial.,  2002; 51:433-42; Sendid, B et al.  J Clin Microbial.,  2004; 42:164-71; Yera, H et al.  Eur J Clin Microbiol Infect Dis.,  2001; 20:864-70; Platenkamp, G J et al.  J Clin Pathol.,  1987; 40:1162-7). It is quite possible, therefore, that a prediction model such as ours based on antibody responses to multiple antigens will ultimately be of greatest utility in combination with cultures and other diagnostic markers. 
     In conclusion, a highly accurate model can be derived using a few rationally selected antigens. Indeed, limiting the number of antigens is desirable since it simplifies large-scale testing by ELISA. Once a prediction model is validated, the precise roles of antibody profiling against candidal antigens in the management of systemic candidiasis can be further investigated in well-designed prospective studies. In addition to diagnosing systemic candidiasis, potential applications of antibody testing include tracking responses to antifungal therapy and identifying high-risk patients who could benefit from preventive or pre-emptive treatment. 
     It should be understood that the examples and embodiments described herein are for illustrative purposes only and that various modifications or changes in light thereof will be suggested to persons skilled in the art and are to be included within the spirit and purview of this application.