Title: Features and overview

Context:
The systematic review conducted for the update of this CPG encompassed interventional studies (primarily  randomized controlled trials [RCTs]) published between March 2009 and December 2016 and targeted nine key questions (KQs) focusing on the means by which the delivery of healthcare could be optimized for  patients on or being considered for LOT. Because a comprehensive review of the evidence related to LOT was not feasible, the nine selected KQs were prioritized from many possible KQs. Therefore, many of the  2010 OT CPG recommendations were considered for inclusion in the updated version of the guideline  without an updated review of the evidence. The section on Recommendations delineates whether or not  the current CPG recommendations were based on an updated evidence review. Appendix H delineates  whether the 2010 OT CPG recommendations were considered for inclusion in the update based on an  updated evidence review or based on the evidence included in the 2010 OT CPG. The section on  Recommendation Categorization further describes the methodology used for the categorization.

Question: Why only nine key questions (KQs) were prioritized from many possible KQs?

Answer: Because a comprehensive review of the evidence related to LOT was not feasible