Title: Recommendations

Context:
Similar to other risk factors, age <30 years should be weighed heavily in the risk-benefit determination for  initiating LOT. Age <30 years is not an absolute contraindication to LOT. There may be some situations  where the benefits of LOT clearly outweigh the risks of OUD and overdose. Hospitalized patients  recovering from battlefield injuries, for example, are known to have less chronic pain, depression, and  PTSD when their pain is aggressively managed starting soon after injury.[93] In those cases, LOT may be  appropriate only if risk mitigation strategies are employed and patients are titrated off LOT as soon as it is  appropriate (see Recommendations 14 and 15).

Question: When may LOT be appropriate?

Answer: only if risk mitigation strategies are employed and patients are titrated off LOT as soon as it is  appropriate