Title: Recommendations

Context:
Short-acting versus Long-acting Opioids: Avoid use of long-acting agents for acute pain (with exception of oxycodone/acetaminophen extended release [ER] tablets), on an as-needed basis, or for initiation of OT.[10,137-139] There is very low quality evidence to recommend for or against short-acting versus long-acting opioids for maintenance of OT.  There were two RCTs included in the evidence review that looked at safety and efficacy. One RCT  comparing long-acting to short-acting dihydrocodeine found no statistically or clinically significant  differences in stability of pain intensity between the two groups, as well as no difference in adverse events. Although study results may be inconclusive due to poor study design, the authors state that they do not  support the use of long-acting agents for chronic non-malignant pain.[140]

Question: Which long-acting agents can be used for acute pain?

Answer: oxycodone/acetaminophen extended release [ER] tablets