PATENT ABSTRACT
Implementing gene expression to study drug action in the central nervous system is complicated by functional heterogeneity because of the existence of many different neuronal subtypes within the mammalian brain. The integration of laser capture microdissection (LCM) and RNA amplification with cDNA microarray technology allows for large-scale gene expression analysis at cellular level. Using this approach, we have generated gene expression profiles of imipramine, a reference antidepressant, and a new putative antidepressant, novelR1 in several laser-captured brain nuclei (locus coeruleus, dorsal raphe, hypothalamic paraventricular nucleus and hippocampus) of rats subjected to the chronic mild stress model (CMS) of depression.

PATENT DESCRIPTION
CROSS-REFERENCE TO RELATED APPLICATION  
       [0001]    This application claims the benefit of United States Provisional Application Ser. No. 60/238,374, filed on Oct. 6, 2000, and U.S. Provisional Application Ser. No. 60/295,782, filed on Jun. 4, 2001. 
     
    
     
       BACKGROUND OF THE INVENTION  
         [0002]    Microarray technology represents a potentially powerful approach to identifying genes specifically expressed in different cell of tissue type [P. O. Brown and D. Botstein, “Exploring the new world of the genome with DNA Microarrays” (1999)  Nat Genet,  21:33-7; D. Shalon, “Gene expression micro-arrays: a new tool for genomic research”, (1998)  Pathol. Biol. (Paris),  46;107-9; S. M. Welford, J. Gregg, E. Chen, D. Garrison, P. H. Sorensen, C. T. Denny and S. F. Nelson, “Detection of differentially expressed genes in primary tumor tissues using representational differences analysis coupled to microarray hybridization” (1998)  Nucleic Acids Res,  26:3059-65]. The application of microarray to the study of gene expression patterns in the central nervous system is complicated by functional heterogeneity because of the existence of many different neuronal subtypes within the mammalian brain [D. H. Geschwind, “Mice, microarrays, and the genetic diversity of the brain [In Process Citation]” (2000)  Proc. Natl. Acad. Sci. USA,  97:10676-8; S. J. Watson, F. Meng, R. C. Thompson and H. Akil, “The ‘chip’ as a specific genetic tool” (2000)  Biol Psychiatry,  48:1147-56]. This heterogeneity consists of literally hundreds of brain nuclei that are in close proximity to each other as well as many different neuronal subtypes in cortical layers of different brain regions. We have demonstrated in a previous study that the integration of laser capture microdissection (LCM), T7 based RNA amplification and cDNA microarrays allows to profile gene expression at cellular level [L. Luo, R. C. Salunga, H. Guo, A. Bittner, K. C. Joy, J. E. Galindo, H. Xiao, K. E. Rogers, J. Wan, M. R. Jackson and M. G. Erlander, “Gene expression profiles of laser-captured adjacent neuronal subtypes” (1999) [published erratum appears in  Nat Med  1999 Mar; 5(3):355], Nat Med, 5:117-22.; R. C. Salunga, H. Guo, L. Luo, A. Bittner, K. C. Joy, J. Chambers, J. Wan, M. R. Jackson and M. G. Erlander, “Gene expression analysis via cDNA microarrays of laser capture microdissected cells from fixed tissue” (1999) In  M. Schena  (Ed.), “DNA microarrays a practical approach”, Oxford University Press, Oxford].  
           [0003]    Recently, expression profiling using microarrays has been successfully used to study the action of the topical anesthetic dyclonine in  S. cerevisiae  [Hughes, 2000 #346]. Implementing gene expression to study drug action in the central nervous system is complicated by functional heterogeneity because of the existence of many different neuronal subtypes within the mammalian brain [Geschwind, 2000 #373] [Watson, 2000 #442]. This heterogeneity consists of literally hundreds of brain nuclei that are in close proximity to each other as well as many different neuronal subtypes in cortical layers of different brain regions. Therefore, we reasoned that to study the in-vivo action of drugs there needed to be from the technical side, the ability to (1) microdissect small numbers of neurons (˜100) from selected nuclei/subnuclei; (2) amplify the extracted mRNA in a reproducible manner; and (3) generate robust cDNA microarray data. The integration of laser capture microdissection (LCM), T7 based aRNA amplification and cDNA microarrays technology allows profiling of gene expression from specific cell type in situ [Luo, 1999 #352] [Salunga, 1999 #347].  
           [0004]    Acute tricyclic antidepressants and other classes of antidepressant have a relatively well defined pharmacological action/target in-vitro of presynaptic reuptake inhibition of biogenic amines (norepinephrine, serotonin, dopamine). However, clinical efficacy requires three to six weeks suggesting that in-vivo a more complex mechanism occurs [Nestler, 1998 #409] [Stanford, 1996 #252]. Given this lag in efficacy, it is reasonable to assume that the mechanism of action of chronic antidepressant treatment in vivo may in part involve the modulation of gene expression. Therefore, gene expression profiling of selected brain nuclei may help to elucidate the chronic mechanisms of antidepressant action.  
         SUMMARY OF THE INVENTION  
         [0005]    The present invention provides gene expression profiles at a cellular level of multiple brain nuclei after CMS±chronic treatment with antidepressant imipramine. Imipramine, a potent inhibitor of norepinephrine (NE) and serotonin (5-HT) uptake was selected as reference compound. In addition, a new putative antidepressant was examined to determine whether different in-vitro pharmacological properties but similar behavioral effects of imipramine and the new compound in the CMS model result in similar gene expression patterns. This new compound displays U2 adrenoceptor and 5-HT 7  receptor antagonism properties [Kennis, 2000 #394]. The present invention also provides potential new targets for drug discovery to identify compounds useful to treat depression and other neurological diseases and/or conditions. 
       
    
    
     BRIEF DESCRIPTION OF THE DRAWINGS  
       [0006]    [0006]FIG. 1: Laser Capture Microdissection from Nissl-Stained Sections (10 μM).  
         [0007]    Panel A: hippocampus including CA1, CA3 and DG before capture  
         [0008]    Panel B: hippocampus after capture of CA1 cells (c) CA1 captured cells.  
         [0009]    Panel C: Scale bar represent 200 μm.  
         [0010]    [0010]FIG. 2: Body Weight and Sucrose Consumption in Animals Exposed to CMS.  
         [0011]    Effect of chronic treatment with vehicle (1 ml/kg 2× per day), imipramine (10 mg/kg/day) and novelR1 (0.16 mg/kg, 2× per day)  
         [0012]    Panel A: on the body weight, and  
         [0013]    Panel B: the consumption of a 1% sucrose solution in controls (open symbols) and in animals exposed to CMS (closed symbols). Treatment commenced following 2 weeks of stress. Values are means +/−SEM.  
         [0014]    *−p&lt;0.05, **−p&lt;0.01, *** −p&lt;0.001; relative to vehicle- or drug-treated control groups.  
         [0015]    −p&lt;0.05, −p&lt;0.01, −p&lt;0.001; relative to drug-treated stressed animals at Week 0.  
         [0016]    [0016]FIG. 3: Experimental Reproducibility of LCM, T7 Based aRNA Amplification and cDNA Microarray Procedure.  
         [0017]    Pair-wise similarities of gene expression profiles measured by the linear correlation coefficient.  
         [0018]    Panel A: average linear correlation coefficient (R) for each brain area (n =3 to 5 per group)  
         [0019]    Panel B: examples of scatter plots showing the individual linear correlation coefficient for two groups of rats (control/vehicle DR and control/vehicle CA3).  
         [0020]    [0020]FIG. 4: Gene Expression Profiling of Laser Captured Brain Nuclei of Vehicle/Control Rats.  
         [0021]    Panel A: table showing the number of genes expressed in each the laser-captured nuclei (100 cells) according our criteria for a call of presence (i.e. 3 fold above background). The number of genes uniquely expressed in one of these nuclei is also given  
         [0022]    Panel B: two-dimensional hierarchical cluster analysis of the 871 genes (horizontal axis) detected in at least one of the region investigated (vertical axis). Red, high intensity (log10 scale), black not expressed (below 3 fold the background). The 7 regions on the vertical axis were assembled into a dendrogram, where items are joined by very short branches if they are similar to each other and by increasingly longer branches as their similarity decreases  
         [0023]    Panel C: distribution of several genes for specific laser-captured brain region, data represent the average fluorescence intensity. Note that the fluorescence intensity readings for vasopressin and oxytocin in PA and MG correspond to the maximal intensity.  
         [0024]    * The anatomical distribution of these genes matched the distribution previously described in the literature: vasopressin [Hallbeck, 1999 #359], oxytocin [Burbach, 1987 #354], somatostatin [Fitzpatrick-McElligott, 1988 #358], dynorphin [Morris, 1986 #364], tyrosine hydroxylase [Tohyama, 1998 #348], serotonin transporter [Swan, 1997 #419], galanin [Tohyama, 1998 #348], RGS14 [Traver, 2000 #416], H 3  histamine receptor [Lovenberg, 1999 #338], mineralocorticoid receptor [Reul, 1985 #424].  
         [0025]    [0025]FIG. 5: In situ Verification of the cDNA Microarray Data for Tyrosine Hydroxylase mRNA by ISHH.  
         [0026]    Autoradiograms of frontal sections (left hemisphere) through the locus coeruleus hybridized with cRNA probes for tyrosine hydroxylase mRNA. (a, c, e) control; (b, d, f) stressed; (a, b) vehicle; (c, d) imipramine treated (10 mg/kg/day); (e, f) novelR1 treated (0.16 mg/kg, 2× per day) (g) Bound radioactivity of tyrosine hydroxylase cRNA probe in locus coeruleus of each group of animals. Values are means ±SEM n =3-5. Differences between control and CMS or drug treated groups were statistically significant. ***p&lt;0.001. Scale bar represents 0.5 cm.  
         [0027]    FIGS.  6 : Overlapping and Non Overlapping Gene Expression Pattern in Unstressed and CMS Drug Treated Rats in the 7 Different Nuclei.  
         [0028]    The diagrams show the number of genes with the indicated patterns.  
         [0029]    Panel A: unstressed and CMS imipramine treated animals  
         [0030]    Panel B: unstressed and CMS novelR1 treated animals  
         [0031]    Panel C: uniquely changed in CMS imipramine and NOVELR1: the subset of genes with an accession number overlapping are listed. 
     
    
     DETAILED DESCRIPTION OF THE INVENTION  
       [0032]    Gene expression profiling of antidepressants should be carried in the context of a behavioral model of depression. The chronic mild stress (CMS) model, a behavioral model of depression for which predictive, face and construct validities have been demonstrated was selected [Willner, 1992 #150] [Willner, 1997 #144] [Yadid, 2000 #422]. The CMS model was developed to mimic anhedonia, a core symptom of depressive disorders. Chronic sequential administration of a variety of mild stressors causes a decrease in responsiveness to rewards in rats, which is reversed by chronic administration of antidepressants drugs [Willner, 1992 #150]. The CMS model of depression also causes a decrease in body weight [Forbes, 1996 #413] but the magnitude of this decrease is minor and the validity, reliability and utility of the CMS is overall well recognized [Yadid, 2000 #422] [Argyropoulos, 1997 #205] #] [Willner, 1996 #226].  
         [0033]    The locus coeruleus (LC), dorsal raphe (DR), hypothalamic paraventricular nucleus (PVN) magno and parvocellular division (MG, PA) and hippocampus (CA1, CA3 and DG) were selected for the present study. About one hundred cells were laser-captured in each of these nuclei. These regions were selected based on the location of the sites of action of the drugs and the critical neuroanatomical substrate for the stress response. In an autoradiographic analysis of the in vivo distribution of [ 3 H]imipramine in rat brain, the locus coeruleus (LC) and the hippocampus have been shown to be the primary sites of action of imipramine [Duncan, 1991 #407]. Imipramine has also been shown to interfere with the serotoninergic transmission, therefore the dorsal raphe was selected in the present study. The LC is a critical neuroanatomical substrate for the stress response [Brady, 1994 #37] [Nestler, 1999 #240] [Valentino, 1998 #71], the PVN was added to the list of the investigated nuclei because of its role in the stress response [Weiss, 1994 #36]. Information on the neuroanatomical distribution of genes is critical for the process of understanding their function in the central nervous system. The integration of laser capture microdissection, T7 based RNA amplification and cDNA microarrays allows dissection of neuronal heterogeneity and at the same time to measure the gene expression level of thousands of genes. We have built a catalogue of rat brain-nuclei specific gene expression profiles. The following seven brain nuclei (100 cells) were analyzed: locus coeruleus (LC), dorsal raphe nucleus (DR), hypothalamic paraventricular (PVN, parvocellular division PA and magnocellular division MG) and hippocampus (CA1, CA3 and DG). Of the 2137 genes (unique mRNAs) interrogated, 871 (40.76%) gave a hybridization signal consistent with a call of presence in at least one brain region (i.e. at least three-fold above background level). The analysis was validated by the agreement of our findings with that of previously documented expression patterns of “signature” genes for specific brain nuclei. For example, abundant mRNA expression encoding the serotonin transporter was detected in DR cells but not detected in the other examined nuclei. The different nuclei investigated were found to have about four to seven percent in unique gene expression. The hierarchical clustering analysis shows that the two divisions of the PVN (PA and MG) were closely related and that similarly the three regions of the hippocampus (CA1, CA3 and DG) shared a similar gene expression profile. This study demonstrates the feasibility and utility of cellular brain nuclei profiling.  
         [0034]    Using the LCM, T7 based amplification and cDNA microarray approach, we have generated a catalogue of cell specific gene expression profiles that can be used to determine which genes are expressed and where in the adult rat brain. Recently, Sandberg et al. [R. Sandberg, R. Yasuda, D. G. Pankratz, T. A. Carter, J. A. Del Rio, L. Wodicka, M. Mayford, D. J. Lockhart and C. Barlow, “Regional and strain-specific gene expression mapping in the adult mouse brain” (2000)  Proc. Natl. Acad. Sci.,  97:11038-43] and Zirlinger et al. [M. Zirlinger, G. Kreiman and D. J. Anderson, “Amygdala-enriched genes identified by microarray technology are restricted to specific amygdaloid subnuclei” (2001)  Proc. Natl. Acad. Sci.  98:5270-5] have demonstrated the utility of brain region expression profiling. In these studies, gene expression analysis was performed on dissected brain regions. In the present study, a more neuroanatomically refined method (i.e. LCM) was introduced to isolate the cells of interest. The LCM technique allows the procurement of a selected cell population [S. J. Watson, F. Meng, R. C. Thompson and H. Akil, “The ‘chip’ as a specific genetic tool” (2000)  Biol Psychiatry,  48:1147-56]. Brain tissues are composed of complex admixtures of different cell types, their biological meaningful analysis necessitate the procurement of a pure sample of the cells of interest. It is likely that general brain region dissection approaches would dilute the concentration of RNAs from neurons with RNAs from millions of potentially unrelated neurons and glia.  
         [0035]    The correlation coefficient underlying the pair-wise similarities of gene expression profiles within one nuclei obtained in the present study demonstrate the reproducibility of the LCM, T7 RNA amplification and cDNA microarray approach. The high concordance between our data and published results validates the approach. However, some false negative findings were observed in the present study. Hallbeck et al. [M. Hallbeck, O. Hermanson and A. Blomqvist, “Distribution of preprovasopressin mRNA in the rat central nervous system” (1999)  J. Comp. Neurol.,  411:181-200] have reported the presence of low level of vasopressin mRNA in the hippocampus by in situ hybridization. In the present study, the level of vasopressin mRNA detected in the hippocampus was found between two- and three-fold different from the background and so, according to our criteria, was classified as not expressed. Low expression of somatostatin mRNA in the hippocampus has also been described in the literature [J. V. Priestley, M. Rethelyi and P. K. Lund, “Semi-quantitative analysis of somatostatin mRNA distribution in the rat central nervous system using in situ hybridization” (1991)  J. Chem. Neuroanat.,  4:131-53]. As observed for vasopressin, the intensity for somatostatin mRNA in the present study was below the criteria used for a call of presence. The stringent criteria used for a call of presence in the present study could account for these discrepancies. Sandberg et al. [R. Sandberg, R. Yasuda, D. G. Pankratz, T. A. Carter, J. A. Del Rio, L. Wodicka, M. Mayford, D. J. Lockhart and C. Barlow, “Regional and strain-specific gene expression mapping in the adult mouse brain” (2000)  Proc. Natl. Acad. Sci.,  97:11038-43] reported in their study that approximately 1% of the genes showing hybridization signals on the array were detected as differentially expressed between the four different brain regions investigated. In the present study, we found that the seven different nuclei investigated have about 4% to 7% in unique gene expression. The higher percentage of uniquely expressed found in our study could reflect the higher sensitivity achieved by the LCM approach.  
         [0036]    In this study, we were able to classify the different laser-captured brain nuclei by hierarchical clustering analysis. As expected, we found that the two divisions of the PVN (PA and MG) were closely related and, similarly, the three regions of the hippocampus shared similar gene expression profiles. The dendrogram in FIG. 3 represents a new approach to classify brain nuclei. In conclusion, this study demonstrates the feasibility and the utility of cellular brain nuclei profiling. The following examples are intended to illustrate but not limit the present invention.  
       EXAMPLE 1  
       [0037]    Behavioral Procedure  
         [0038]    The stress procedure was conducted on male Wistar rats as previously described [Dziedzicka-Wasylewska, 1997 #224]. On the basis of sucrose intake scores following two weeks of stress, both stressed and control groups were divided further into matched subgroups (n=8), and for the subsequent five weeks received twice-daily intraperitoneal injections of vehicle (isotonic mannitol solution, pH 4.0, 1 ml/kg) or novelR1 (0.16 mg/kg). Once-daily intraperitoneal injections of imipramine (10 mg/kg) were used as the reference treatment. At this dose, imipramine has been shown to cause stable and comparable effects after chronic treatment in all previous studies using this experimental protocol [Willner, 1997 #144]. Sucrose tests were carried out twenty-four hours following the last drug injection (in the case of b.i.d. regime, the second injections on the day preceding the sucrose tests were omitted).  
         [0039]    Drugs  
         [0040]    The following agents were used: imipramine HCl (RBI, Natick, Mass.) and novelR1.  
         [0041]    Statistics  
         [0042]    The behavioral results obtained in this study were analyzed by multiple analysis of variance with three between-subjects factors (stress/control, drug treatments and successive sucrose tests). Fisher&#39;s LSD test was used for post-hoc comparisons of means.  
         [0043]    Tissue Preparation  
         [0044]    Twenty-four hours after the final injection of vehicle, imipramine or novelR1, five representative animals from each group were decapitated, and their brains were removed, placed in cryomolds, covered with Tissue-Tek tissue embedding medium (OTC) and snap-frozen in dry ice-cold 2 methyl butane (−60° C.). Ten μm-thick coronal sections in the mid-regions of the PVN (bregma—1.80 mm), hippocampus (bregma—3.30 mm), DR (bregma—1.78 mm) and LC (bregma—9.80 mm) were cut using a cryostat, mounted on non-coated, clear microscope slides and immediately frozen on a block of dry ice. The sections were stored at −70° C.  
         [0045]    Laser Capture Microdissection  
         [0046]    A quick Nissl (cresyl violet acetate) staining was used to identify the neurons as described [Salunga, 1999 #347]. The PixCell II System from Arcturus Engineering, Inc. (Mountain View, Calif.) was used for LCM. According to the manufacturer&#39;s protocol, one hundred neurons were captured in each region of interest of each animal (LC, DR, MG, PA, CA1, CA3 and DG). Example of laser-captured cells in CA1 region is shown in FIG. 1.  
         [0047]    RNA Extraction and Amplification of LCM Samples  
         [0048]    The total RNA was extracted from the individual LCM samples as described [Salunga, 1999 #347] with modifications as specified below. For total RNA extraction, a small volume (20 μl/LCM sample) of denaturing buffer (Micro RNA isolation kit, Stratagene: San Diego, Calif.) containing 2-mercaptoethanol (10 μl/ml, Sigma, St Louis, Mo.) and polyinosine (300 ng/LCM sample, Sigma: St Louis, Mo.) was used. The samples were incubated at 42° C. for ten minutes, and loaded onto a pre-rinsed Microcon-100 column (Millipore: Bedford, Mass.). After two rinses with 500 μl Rnase-free water, the columns were inverted and the samples collected by brief centrifugation. The samples were then processed for two rounds of RNA amplification as described [Salunga, 1999 #347] with modifications for the DNA and RNA purification steps. Quiaquick PCR purification kit (Qiagen: Valencia, Calif.) and RNAeasy Mini Kit (Qiagen: Valencia, Calif.) were used for purification steps. Polyinosine (100 ng) was added to each sample before purification of DNA or aRNA.  
         [0049]    cDNA Microarray  
         [0050]    A cDNA microarray containing 2147 cDNA clones (corresponds to 2137 unique mRNAs) was used in this study. cDNA clones were obtained commercially from Research Genetics (IMAGE consortium), Incyte Genomics as well as internal sources. All clones were verified by DNA sequencing. Each clone was printed as two independent spots on a given chip. A contact pin microarrayer (Generation III Array Spotter, Molecular Dynamics) was used to spot the clones in duplicate. Microarrays were hybridized and scanned with a confocal laser scanner (Array Scanner, Molecular Dynamics) with excitation at 532nm and collection through a 550 to 600nm band width filter, the PMT set to 630V. Image analysis was performed as previously described [Salunga, 1999 #347].  
         [0051]    Statistical Analysis  
         [0052]    Hybridization of each sample was performed on two identical microarrays. Each microarray was normalized at the 75 percentile (intensity of the 75 percentile was scaled to 100). Intensity of each clone on an individual microarray was then measured as an average of the intensities of the two corresponding spots, and the intensity of each clone in the sample was further determined as average of the intensities on the two identical chips. The pair-wise similarity of gene expression profiles within a group of same samples (same cell type under identical treatment) was examined by scatter-plot and the correlation coefficient was calculated. Samples having a correlation coefficient of R &lt;0.89 with respect to the majority were treated as out-liers and were excluded for further analysis (at least three rats were included in each group). The intensity of each clone in one particular type of samples was subsequently further defined as the median of intensities of that clone in remaining qualified samples in that group. The resulting intensity matrix (N×M) (N: number of clones; M: number of sample types) was further normalized (spline normalization) so that the distribution of the intensities of all the clones for each individual sample type was fitted to a smooth cubic B-spline. The spline normalization could reduce abnormality in the distribution of the intensities in particular samples caused by saturation in image processing.  
         [0053]    In addition to the 2147 clones, fifteen plant cDNA were printed on the same microarray. The intensities of these fifteen plant cDNAs were measured and processed in the same manner as other clones, and used as negative controls. The average intensity of the fifteen plant genes in all M types of samples was defined as background. Each clone was then classified as absent in a cell population if its medium intensity was below the three-fold of the background; or as present if its medium intensity was three-fold above the background.  
         [0054]    The ratio (fold change) of gene expression between two samples was calculated after applying *i minimum threshold at the background of plant genes (intensity lower than background was re-set to background). The criteria used to select statistically significant fold changes in gene expression between two samples was at least a 1.8 fold change. Hierarchical clustering was generated by using Cluster software (Stanford).  
         [0055]    Quantitative In Situ Hybridization Histochemistry.  
         [0056]    In situ hybridization histochemistry was performed according to the procedures described [Bonaventure, 1998 #353] on adjacent tissue sections of the one used for LCM. The plasmid (pBluescript II SK, Stratagene, San Diego, Calif.) containing the cDNA coding for tyrosine hydroxylase (GB:M10244) was linearized and [ 35 S]UTP labeled cRNA probe was generated by in vitro transcription with T7 polymerase. Sections were hybridized at 50° C. with 1.106 c.p.m of [ 35 S]UTP labeled cRNA probe (80 μl per section). After high stringency washes, the sections were exposed to Kodak BiomaxMR film for sixteen hours. [ 14 C] standard strips (American Radiolabeled chemicals Inc., St Louis, Missouri) were co-exposed to allow densitometry. Autoradiograms were quantified with the aid of an MCID-M4 3.0 Image Analysis system (Imaging Research, St. Catharines, Ontario, Canada). Optical densities in the LC were transformed into levels of bound radioactivity after calibration of the image analyzer with grey-values generated by co-exposed standards. The hybridization signal was expressed as μCi/g. The Student&#39;s t-test was used for comparison between the groups.  
         [0057]    Body Weight is Unchanged by CMS or Drug Treatment.  
         [0058]    At the start of the study (Baseline) all animals weighed approximately 320 grams and after the initial two weeks of stress (Week 0) the body weights of control and stressed animals were comparable (375 +/−6 and 372 +/−9 g, respectively). At the end of the treatment period (Week 5), body weights of vehicle-treated control and stressed animals were comparable [Group effect: F(1,14)=0.011; p=0.919]. As compared to vehicle-treated groups, neither imipramine nor novelR1 had any significant effect on body weights in controls [IMI: F(1,14)=1.764; NS, novelR1: F(1,14)=1.241; NS] and in stressed [IMI: F(1,14)=1.002; NS, novelR1: F(1,14)=0.518; NS] (FIG. 2 a ).  
         [0059]    Sucrose Intake is Normalized in CMS Rats by Chronic Imipramine/NovelR1 Treatment.  
         [0060]    In the final baseline test, all animals drank approximately 13 grams of sucrose solution. Following the initial two weeks of stress (Week 0), the intakes remained at similar level in controls but fell to approximately 8 grams in stressed animals, resulting in a significant Group effect [F(1,14) 11.159; p&lt;0.01]. As shown in FIG. 2 b , such a difference between control and stressed animals treated with vehicle persisted for the remainder of the experiment [F(1 1,84)=5.563; p&lt;0.001] and at the end of treatment period, the sucrose consumption in stressed animals receiving vehicle was significantly lower than that measured in control group (p&lt;0.001). As compared to chronic vehicle administration, imipramine did not change the sucrose intake in control animals [Treatment effect: F(1,84)=3.344; NS, Treatment×Weeks interaction: F(5,84)=0.313; NS]. However, in stressed animals, imipramine gradually increased the sucrose consumption, resulting in a significant Treatment effect [F(1,84)=61.277; p&lt;0.001], Treatment×Weeks interaction [F(5,84)=4.117; p&lt;0.01], and Treatment×Group interaction [F(1,168)=13.353; p&lt;0.001] after three weeks of treatment (p&lt;0.001). This effect was maintained thereafter and at the end of treatment period (Week 5), the amount of sucrose solution consumed by these animals was comparable to that of vehicle-treated controls (p=0.168) and significantly higher than that of vehicle-treated stressed animals (p&lt;0.001). The novelR1 like imipramine had no significant effect on the consumption of sucrose solution in control animals [Treatment effect: F(1,84)=0.315; NS, Treatment×Weeks interaction: F(5,84)=0.599; NS]. However, like imipramine, novelR1 fully reversed in stressed animals the CMS-induced deficit in sucrose consumption resulting in a significant Treatment effect [F(1.84)=51.123; p&lt;0.001], Treatment×Weeks interaction [F(5,84)=2.882; p&lt;0.05], and Treatment×Group interaction [F(1,168)=14.238; p&lt;0.001].  
         [0061]    As compared to Week 0 scores, the increase of sucrose intake reached statistical significance after two weeks of treatment with novelR1 (p=0.043). This effects was maintained thereafter and at the end of treatment period, the intake in this group of stressed animals did not differ from those measured in vehicle-treated controls (p=0.501) and were significantly higher than those of vehicle-treated stressed animals (p=0.001).  
         [0062]    The Greatest Number of Genes Changing Their Expression Level in Response to the CMS Paradigm in Untreated Rats was Found in LC.  
         [0063]    A total of 80 genes (3.79 %) were found to change their expression level in response to the CMS paradigm in untreated animals (versus the control/vehicle group). The greatest number of genes changing their expression level was observed in LC (53 genes)&gt;DG (10 genes)&gt;PA (9 genes), CA1 (9 genes)&gt;DR (2 genes), CA3 (2 genes), MG (1 gene) in Table 1 (see below).  
                                                                                                                                                                                                                                                                                                                           TABLE 1                               FOLD           ACC. NO   GENE   (CMS vs ctrl)   NUCLEUS                                Catecholamine synthesis            M10144   Tyrosine hydroxylase   1.85   LC            Neuropeptides            A1045437   Neuropeptide Y**   2.11   DG       AA955779   Galanin   2.06   PA       M10088   dynorphin**   −2.52   DG       RNU10071   CART   −1.90   LC            Receptors, ion channels            AF052746   Chloride channel CaCC   3.27   LC       M81830   Somatostatin R2 (SSR2)   2.77   LC       AF027955   GPR27 R   −1.92   LC       Z30425   Nuclear receptor/orphan   −1.90   DG           MB67/CAR       L14618   Calcitonin R   −1.81   PA       L14618   Calcitonin R**   −1.80   LC           GABA signaling       L08493   GABA-A R alpha4 subunit   2.24   CA1       X54673   GAT1   −2.05   LC            Glutamate signaling            X94552   mGlu7 R   −2.21   LC       M81886   glutamate R 1*   −2.03   CA1       M64752   glutamate R 1*   −1.89   CAl       HSU08107   NMDA R subunit   2.23   LC            Calcium            AA819346   Parvalbumin**   1.93   DG       M31178   calbindin D28   1.87   CA1       M31178   calbindin D28   −2.21   LC       AA819345   Parvalbumin   −1.99   LC       L10284   Calnexin   −1.87   LC            Signal transduction            D83407   ZAKI-4*   −1.80   DR            Heat shock protein            M86389   Hsp27   −1.85   PA            Plasticity            X51396   MAP1B   −2.11   CA1       X60370   MAP1B   −1.83   CA1            Proteasome            D29956   ubiquitin isopeptidase   1.97   LC       D17296   Polyubiquitin   −2.01   LC       W07641   ubiquit-like protein SMT3B   −2.00   LC            Transcription factor            Y10926   RBP-L   2.16   LC       Y07688   NfiX   −2.38   LC       AF057691   TCF-3   −1.83   DR       W65013   similar to X07384 GLI   −1.85   CA3           PROTEIN            p53            U67885   p53 binding prot 1   −2.37   LC       U28789   PACT   −2.01   LC            Others            X58526   L1 element   −2.39   LC       X58526   L1 element   −2.35   DG       100256   Sequence 7 from U.S. Pat.   2.38   LC           No. 4900811**       100256   Sequence 7 from U.S. Pat.   −1.93   PA           No. 4900811                  
 
         [0064]    These genes were classified in functional families (i.e. catecholamine synthesis, neuropeptides, receptors or ion channels, GABA signaling, glutamate signaling, calcium, signal transduction, heat-shock protein, plasticity, proteasome, transcription factors and p53). The genes that could be classified in these functional families and with an accession number are listed in Table 2 (containing 39 genes).  
                                               TABLE 2                           Number of genes detected in each laser-captured nuclei (100 cells)       according our criteria for a call of presence (i.e. three-fold above       background). The number of genes uniquely expressed in one of these       nuclei is also given.                Detected   Unique                            CA1   499   32           CA3   527   22           DG   527   24           LC   513   43           DR   510   38           MG   519   21           PA   520   25                      
 
         [0065]    The increase in expression level of tyrosine hydroxylase mRNA (GB: M10244) in the LC of CMS/vehicle rats was further confirmed by quantitative in situ hybridization (FIG. 5 a  and  b ).  
         [0066]    For the glutamate receptor 1 (GB: M81886, M64752) and the microtubule associated protein MAPI (GB: X51396, X60370) two different clones (from different species) were spotted on the microarray and consistent changes in gene expression level were observed for both clones as shown in Table 1. MAP1B plays an important role in the extension of axons and dendrites.  
         [0067]    The chloride channel CaCC (GB: AF052746) and the somatostatin receptor 2 (GB: M81830) mRNAs showed the biggest amplitudes of changes of their expression levels in response to CMS (i.e 3.37-fold and 2.77-fold, respectively).  
         [0068]    Six genes (five with an accession number) were found to change their expression level in the CMS/vehicle group in two different laser-captured nuclei (i.e. calcitonin receptor GB: L14618 in PA and LC, parvalbumin GB: AA819346 in DG and LC, calbindin D28 GB: M31178 in CA1 and LC, LI element GB: X58526 in LC and DG and GB: 100256 in LC and PA) (Table 1). Noteworthy, two calcium-ion binding protein (parvalbumin and calbindin D28) were found among these six genes.  
         [0069]    At the end of the behavioral experiment, two different endpoints in sucrose consumption levels were observed: 13 grams of sucrose intake including the following groups vehicle/control, imipramine/control, imipramine/CMS, novelR1/control, novelR1/CMS) and 8 grams of sucrose intake including the vehicle/CMS group (FIG. 2 b ). The differences in gene expression level between these two groups (i.e. 8 grams versus 13 grams) reflects either changes causal to the decrease in sucrose consumption level or changes in response/adaptation to the CMS paradigm. A total of 30 genes (1.4%) were found to change their expression level in the untreated CMS group uniquely (i.e. no change in any of the other comparisons performed). The largest set of genes changing their expression level after CMS exposure uniquely was observed in LC (26)&gt;PA (2)&gt;DR (1), CA1 (1). These genes are listed in Table 1. Interestingly, in the GABA signaling pathway the expression level of both GABA-A receptor and GAT-1 was changed by the CMS paradigm uniquely.  
         [0070]    Overall Both Drugs Changed the Expression Level of a Larger Set of Genes Than the CMS Paradigm and NovelR1 Changed the Expression Level of More Genes Than Imipramine in Unstressed Rats.  
         [0071]    Overall imipramine and novelR1 were found to change the expression level of more genes than the CMS paradigm in control animals (CMS: 80 genes, 3.79%; imipramine: 86 genes, 4%; novelR1: 306 genes, 14%). These changes in gene expression levels induced by imipramine or novelR1 in unstressed rats do not reflect a change in sucrose uptake. In all, the nuclei investigated (excepted CA3 and MG), chronic treatment with novelR1 changed the expression level of more genes than imipramine in control animals (FIG. 6).  
         [0072]    For both drugs genes that changed their expression levels in more than one of the investigated nuclei were found (imipramine: 12 genes: Table 3, R10747: 42 genes: Table 4). Both drugs were found to increase tyrosine hydroxylase mRNA levels in LC (fold increase versus control/vehicle: imipramine, 2.27; novelR1, 3.37). This up-regulation of tyrosine hydroxylase mRNA level was confirmed by in situ hybridization (FIGS. 5 c  and  5   d ). Noteworthy, the pterin-4a-carbinolamine dehydratase (DCoH or PCD, GB: AA901316) which catalyses the recycling of the cofactor biopterin [Depaepe, 2000 #439] shared a similar expression pattern in LC (fold increase versus vehicle/control: imipramine, 1.98; novelR1, 2.70). DcoH is requested in association with tyrosine hydroxylase for dopamine biosynthesis. Co-localization of DCoH and tyrosine hydroxylase in LC neurons has been previously demonstrated [Depaepe, 2000 #439] 
                                                                                                                                                                                                                                                                                                                                                                           TABLE 3                               IMINCMS           ACC. NO.   GENE NAME   vs. IMI   NUCLEI                                Apoptosis            U67885   p53 binding prot 1   3.12   DG       U59746   Bcl-w   2.00   CA1       AF022223   BAG-1   1.83   DR            Catecholamine synthesis            AA142680   dopamine beta-hydroxylase   1.95   LC       A1044610   dopa decarboxylase   1.81   LC            Energy production            V01556   mitochondrial nenome   2.36   DG           fragment       V00680   mitochondrial genes coding   1.90   CA3           for 16S and 12S       V00681   mitochondrial genes for   1.84   MG           16S       V00681   mitochondrial genes for   −2.85   DR           16S       X14848   mitochondrial genome   −2.32   CA1       V00681   mitochondrial genes for   −2.07   CA1           16S       V00681   mitochondrial genes for   −2.04   PA           16S       V01556   mitochondrial genome   −1.99   DR           fragment       V00680   mitochondrial genes coding   −1.93   CA1           for 16S and 12S            GABA signaling            L08495   GABA receptor alpha6   2.56   DG       X54673   GAT1   2.24   CA1       X54673   GAT1   2.14   DG       X14767   GABA-A receptor, beta 1   1.96   CA1           subunit       X15376   GABA-A receptor, gamma   2.00   DG           2 subunit            Glutamate signaling            AA297071   Similar to N-methyl-D-   1.97   LC           aspartate glutamate receptor       U16129   Glutamate receptor (GluR4)   2.27   DG            Growth factors            M21571   platelet-derived growth   1.96   CA1           factor (PDGFA) A chain       U66198   FGF13   1.91   CA1       U66198   FGF13   2.27   DG            Heat shock protein            M19645   BiP/GRP78/ER resident   2.18   LC           HSP70       D13627   TCP-1 Hsp60, theta subunit   2.06   DR       AA823192   heat-shock protein 40   2.03   LC       X15187   HSP90   1.91   DR       M11942   70 kd heat-shock-like   1.89   LC           protein       X63368   HSJ1   1.88   CA1            Neuropeptides            AI045437   neuropeptide Y   2.56   LC       AA818532   gamma-preprotachykinin A   1.99   DR       M10088   Dynorphin   1.86   MG            Plasticity            M16228   GAP-43   2.59   DG       X51396   MAP1B   −4.65   DG            Proteasome            U44839   ubiquitin C-terminal   4.27   DG           hydrolase       D10699   ubiquitin carboxyl-terminal   2.17   LC           hydrolase       D00761   proteasome beta 1 subunit   2.09   DR       U44839   ubiquitin C-terminal   1.93   LC           hydrolase       AA859300   proteasomes C2 component   1.90   DR       W07641   ubiquit.-like protein   −2.79   DG           SMT3B (SUMO-1)       X99585   ubiquit.-like protein   −2.60   DG           SMT3B (SUMO-1)       M29859   proteasomes C2 component   −2.34   DG       D00763   proteasome alpha 4 subunit   −2.31   DG       X99585   ubiquit.-like protein   −1.99   MG           SMT3B (SUMO-1)       AF079564   ubiquitin carboxy-terminal   −1.87   DR           hydrolase ubp41       U75362   ubiquitin carboxy terminal   −1.84   DG           hydrolase       M29859   proteasomes C2 component   −1.83   MG       AA859229   ubiquitin conjugating   −1.82   DG           enzyme            Receptors, ions channels            Y07521   Kv3.1a = NGK2 potassium   2.94   DG           channel; V-gated       U33267   Human glycine receptor   2.60   DG           beta subunit (GLRB)           mRNA, complete cds           H3 Histamine Rec   2.09   DR       L14618   Calcitonin Rec   2.06   LC       X66842   Serotonin 2B Rec   2.05   MG       Z30425   Nuclear receptor/orphan   2.03   MG           MB67/CAR       AF064876   BCNG-1 hyperpolarization   2.03 DG           NSC channel = HCN1 =           HAC2       AF027955   GPR27 Rec   1.96   DG       Y10148   NTR2 receptor   1.94   DG           H3 Histamine Rec*   1.93   LC       X97121   Neurotensin 2 Rec   1.90   DG       M81253   Kv3.4 gene   1.86   LC       AA002993   Potassium channel Kv3.4a   1.85   DR           (Raw3), V-gated       U07225   Purinergic (P2U)   2.88   DG       AI058645   Kv4.3 potassium channel   2.60   DG       X66842   Serotonin 2B Rec   2.23   DR       X66842   Setotonin 2B Rec   1.92   PA       Z30425   Nuclear receptor/orphan   1.88   DR           MB67/CAR       U07225   Purinerpic (P2U)   1.87   PA       U12194   voltage-gated Na + channel   1.83   LC           beta-1 sub (SCN1B) gene       M21948   dihydropyridine-sens Ca   1.83   CA3           channel alpha-2 sub       M24898   Nuclear receptor alpha1   1.81   DG           for thyroid horm            Signa transduction            D83407   ZAKI-4   3.41   DG       M38194   extracellular signal-   2.26   LC           regulated kinase 1       M12673   guanine nucleotide-binding   −4.12   DR           protein G-s, alpha       M29871   ras-related C3 botulinum   −2.69   LC           toxin substrate (rac)       D14425   Calcineurin   −2.24   DG       M60156   Go alpha   −1.89   DR            Transcription factor            AF057691   TCF-3   3.35   DG       AF012923   Wig-1   2.22   LC       AF065386   Jab1   2.14   DR       W65013   Similar to X07384 GLI   −3.24   DG           PROTEIN       X17163   c-jun   −2.50   DG       X12740   C-Jun of the transcription   −1.85   DG           factor AP-1            Others            M25888   Lipophilin   7.94   DG       I00256   Sequence 7 from U.S. Pat.   5.89   DG           No. 4900811       D28875   Osreonectin   3.83   DG       U49099   cis-Golgi p28 (p28)   2.14   DG       D28875   Osteonectin   2.07   PA       P11661   nadh-ubiquinone ox   1.89   DG       I00256   Sequence 7 from U.S. Pat.   1.89   LC           No. 4900811       Z26634   ankyrin brain variant,   2.63   PA           ANKB       M89646   ribosomal protein S24   2.32   DR       P11661   nadh-ubiquinone ox   2.10   CA1       M89646   ribosom protein S24   2.10   DG       M25888   lipophilin   2.09   CA1       M89646   ribosornal protein S24   −1.98   LC       U49099   cis-Golgi p28 (p28)   −1.94   LC       Z26634   ankyrin brain variant,   −1.90   DG           ANKB                  
 
         [0073]    [0073]                                                                                                                                                                                                                                                                           TABLE 4                               R107474NCMS           ACC. No.   GENE NAME   vs. R107474   NUCLEI                                Apoptosis            U59746   Bcl-w   2.11   DR       AF022223   BAG-1   2.05   LC       U59746   Bcl-w   1.85   CA1       U67885   p53 binding prot 1   1.84   PA            Calcium            AA819345   parvalbumin   3.18   CA1       AA819345   Parvalbumin   2.23   DR       M31178   calbindin D28   2.20   CA1            catecholamine synthesis            AA142680   dopamine beta-   2.34   LC           hydroxylase*            energy production            M29341   glyceraldehyde-3-   2.24   LC           phosphate dehydrogenase       X02231   glyceraldehyde-3-   2.09   LC           phosphate dehydrogenase       V01556   mitochondria genome   2.07   MG           fragment       M35826   mitochondrial NADH-   1.96   PA           dehydrogenase (NDI)            glutamate signaling            U08107   N-methyl-D-aspartate   1.85   CA3           receptor subunit       U08107   N-methyl-D-aspartate   1.81   DG           receptor subunit       M81886   glutamate rec type 1   −2.58   CA1           HBGR1)       U08 107   N-methyl-D-aspartate   −2.46   DR           receptor subunit       M64752   glutamate rec sub   −2.35   CA1           (GluH1)            Plasticity            M16228   GAP-43   2.03   LC       X60370   MAP1B   −2.21   CA3            receptors, ions channels            Y07521   Kv3.1a = NGK2   2.41   PA           potassium channel; V-           gated       AA875142   5HT3 receptor mRNA   2.08   LC           H3 Histamine Rec*   2.05   LC       AJ225124   Hyperpolarization-act   1.82   LC           cation channel HAC3       AA427267   SCN9a = PN1 Sodium   1.81   LC           Channel alpha, V-gated       M59980   K Channel   −2.24   CA1       AA819622   thrombin receptor   −2.08   DG       L28175   Prostaglandin EP2   −1.99   LC       U12194   voltage-gated Na+   −1.83   LC           channel beta-1 sub-           (SCN1B) gene            signal transduction            AI071860   RGS14   2.64   CA1       M23612   GTPase-activating   2.16   CA1           protein (GAP)       M29870   ras-related C3 botulinum   2.01   DR           toxin substrate (rac)            transcription factors            W65013   Similar to X07384 GLI   −2.16   CA1           PROTEIN.       J04509   JUN-D prot   −2.10   DR       AF062566   Sp1   −1.94   LC            Others            M30952   28S ribosomal RNA gene   2.92   PA           fragment       U20553   P57   2.18   PA       M30952   28S ribosomal RNA gene   2.14   MG           fragment       M93056   monocyte/neutrophil   2.12   PA           elastase inhibitor       X92106   Bleomycin hydrolase   2.08   PA       U20553   P57   1.98   DG       X92106   Bleomycin hydrolase   1.87   CA3       M29548   elongation factor 1-alpha   1.83   DR           (EF1A)       M93056   monocyte/neutrophil   1.80   DG           elastase inhibitor       M29548   elongation factor 1-   −1.98   CA1           alpha (EF1A)       M89646   ribosomal protein S24   −1.94   CA1       M89646   ribosornal protein S24   −1.89   CA1       X95591   ClD protein   −1.85   CA1       X95591   ClD protein   −1.80   CA3                    
         [0074]    The largest set of genes changing their expression level after chronic treatment with novelR1 was found in DG. Among these genes, the primary site of action of novelR1, the a2c adrenoceptor mRNA (GB: M99376) level was found to be increased (fold difference versus control/vehicle: 3.62).  
         [0075]    Overlaps in the gene expression patterns of imipramine and novelR1 in unstressed animals were observed in PA (thirteen genes)&gt;LC (ten genes), DG (ten genes)&gt;DR (five genes)&gt;CA1 (four genes)&gt;MG (two genes). Among these overlapping genes, six (three with an accession number) were found to change their expression levels in two different nuclei (heat-shock protein 27, GB: M86389 in PA and DR; Gs, GB: M12773 in MG and PA; 5-HT 2 B receptor, GB: X66842 in DG and CA1).  
         [0076]    35% of the Genes Changing Their Expression Level in Response to the CMS Paradigm were Antagonized by Both Drugs Treatment.  
         [0077]    Imipramine and novelR1 were found to antagonize the changes in gene expression level induced by the CMS paradigm of a similar number of genes (imipramine: 53 genes, novelR1: 55 genes). This corresponds to 68% to 69% of the changes induced by the CMS paradigm. For twenty-eight of these genes overlap in the gene expression profile of imipramine and novelR1 were observed.  
         [0078]    The increase in expression level of tyrosine hydroxylase mRNA induced by the CMS paradigm was not antagonized by chronic imipramine or novelR1 treatment in LC. The level of tyrosine hydroxylase mRNA were found to be up-regulated in the imipramine or novelR1/CMS group (fold increase versus vehicle/control: imipramine, 3.12; novelR1, 4.41). The up-regulation of tyrosine hydroxylase mRNA level was also confirmed by in situ hybridization (FIGS. 5 e  and  5   f ). The level of dopamine β hydroxylase (GB: AA142680) mRNA, another enzyme involved in the catecholamine biosynthesis, was also increased by both drugs in CMS rats in LC (fold increase versus vehicle/control: imipramine, 1.95; novelR1, 2.34). Similarly, DcoH mRNA level was increased (fold increase versus vehicle/control: imipramine, 2.30; novelR1, 2.67).  
         [0079]    In CMS rats Both Drugs Changed the Expression Level of a Similar Number of Genes in LC, DR, CA1, CA3 and PA but with Minor Overlaps in Their Expression Profiles.  
         [0080]    In LC, DR, CA1, CA3 and PA, imipramine changed the expression level of a larger set of genes in CMS rats than in unstressed rats (FIG. 6 a ), whereas novelR1 changed the expression level of a similar number of genes in CMS and unstressed rats (FIG. 6 b ). Administration of imipramine or novelR1 to CMS animals normalized the sucrose intake to the control level (FIG. 2 b ). The genes that change their expression level in the drug treated/CMS group but not in the drug treated/control group could reflect a drug +CMS interaction. These changes in gene expression are either causal to the change in sucrose intake from 8 grams to 13 grams or are responding to the new behavioral state. Both drugs yield a similar number of genes reflecting the drug/CMS interaction in LC, DR, CA1, CA3 and PA. In DG and MG, the imipramine/CMS interaction induced greatest changes in gene expression than the novelR1/CMS interaction.  
         [0081]    Minor overlaps in genes expression patterns between imipramine and novelR1 in CMS rats were observed: LC (four genes)&gt;CA1 (two genes)&gt;DR (one gene), PA (one gene). The overlapping genes with an accession numbers are listed in FIG. 6. Imipramine changed the expression level of a total of 184 genes in CMS rats, whereas novelR1 changed the expression level of 91 genes. The genes with an accession number were classified in functional families and are listed in Table 2 (imipramine) and Table 3 (novelR1). Thirty genes were found to change their expression level in more than one nucleus for imipramine and twelve genes for novelR1.  
       EXAMPLE 2  
       [0082]    2.1. Tissue Preparation  
         [0083]    Five adult male Wistar rats (423 g±22) that were used as control animals in a behavioral paradigm were decapitated, their brains were removed, placed in cryomolds, covered with Tissue-Tek tissue embedding medium (OTC) and snap-frozen in dry ice-cold 2 methyl butane (−60° C.). Ten tm-thick coronal sections in the mid-regions of the PVN (bregma—1.80 mm), hippocampus (bregma—3.30 mm), DR (bregma—1.78 mm) and LC (bregma—9.80 mm) were cut using a cryostat, mounted on non-coated, clear microscope slides and immediately frozen on a block of dry ice. The sections were stored at −70° C. All efforts were made to minimize animal suffering and reduce the number of animals used.  
         [0084]    2.2. Laser Capture Microdissection  
         [0085]    A quick Nissl (cresyl violet acetate) staining was used to identify the neurons as described [R. C. Salunga, H. Guo, L. Luo, A. Bittner, K. C. Joy, J. Chambers, J. Wan, M. R. Jackson and M. G. Erlander, “Gene expression analysis via cDNA microarrays of laser capture microdissected cells from fixed tissue” (1999) In  M. Schena  (Ed.), “DNA microarrays a practical approach”, Oxford University Press, Oxford]. The PixCell II System from Arcturus Engineering, Inc. (Mountain View, Calif.) was used for LCM. According to the manufacturer&#39;s protocol, one hundred neurons were captured in each region of interest of each animal (LC, DR, MG, PA, CA1, CA3 and DG). Example of laser-captured cells in CA1 region is shown in FIG. 1.  
         [0086]    2.3. RNA Extraction and Amplification of LCM Samples  
         [0087]    The total RNA was extracted from the individual LCM samples as described [R. C. Salunga, H. Guo, L. Luo, A. Bittner, K. C. Joy, J. Chambers, J. Wan, M. R. Jackson and M. G. Erlander, “Gene expression analysis via cDNA microarrays of laser capture microdissected cells from fixed tissue” (1999) In  M. Schena  (Ed.), “DNA microarrays a practical approach”, Oxford University Press, Oxford] with modifications as specified below. For total RNA extraction, a small volume (20 μl/LCM sample) of denaturing buffer (Micro RNA isolation kit, Stratagene: San Diego, Calif.) containing 2-mercaptoethanol (10 μl/ml, Sigma: St Louis, Mo.) and polyinosine (300 ng/LCM sample, Sigma: St Louis, Mo.) was used. The samples were incubated at 42° C. for ten minutes, and loaded onto a pre-rinsed Microcon-100 column (Millipore: Bedford, Mass.). After two rinses with 500 μl Rnase-free water, the columns were inverted and the samples collected by brief centrifugation. The samples were then processed for two rounds of RNA amplification as described [R. C. Salunga, H. Guo, L. Luo, A. Bittner, K. C. Joy, J. Chambers, J. Wan, M. R. Jackson and M. G. Erlander, “Gene expression analysis via cDNA microarrays of laser capture microdissected cells from fixed tissue” (1999) In  M. Schena  (Ed.), “DNA microarrays a practical approach”, Oxford University Press, Oxford] with modifications for the DNA and RNA purification steps. Quiaquick PCR purification kit (Qiagen: Valencia, California) and RNAeasy Mini Kit (Qiagen: Valencia, California) were used for purification steps. Polyinosine (100 ng) was added to each sample before purification of DNA or aRNA.  
         [0088]    2.4. cDNA Microarray  
         [0089]    A cDNA microarray containing 2147 cDNA clones (corresponds to 2137 unique mRNAs) was used in this study. cDNA clones were obtained commercially from Research Genetics (IMAGE consortium), Incyte Genomics, as well as internal sources. All clones were verified by DNA sequencing. Each clone was printed as two independent spots on a given chip. A contact pin microarrayer (Generation III Array Spotter, Molecular Dynamics) was used to spot the clones in duplicate. Microarrays were hybridized and scanned with a confocal laser scanner (Array Scanner, Molecular Dynamics) with excitation at 532 nm and collection through a 550 to 600 nm band width filter, the PMT set to 630V. Image analysis performed as previously described [R. C. Salunga, H. Guo, L. Luo, A. Bittner, K. C. Joy, J. Chambers, J. Wan, M. R. Jackson and M. G. Erlander, “Gene expression analysis via cDNA microarrays of laser capture microdissected cells from fixed tissue” (1999) In  M. Schena  (Ed.), “DNA microarrays a practical approach”, Oxford University Press, Oxford].  
         [0090]    2.5. Statistical Analysis  
         [0091]    Hybridization of each sample was performed on two identical microarrays. Each microarray was normalized at the 75 percentile (intensity of the 75 percentile was scaled to 100). Intensity of each clone on an individual microarray was then measured as an average of the intensities of the two corresponding spots, and the intensity of each clone in the sample was further determined as average of the intensities on the two identical chips. The pair-wise similarity of gene expression profiles within a same cell type was examined by scatter-plot and the correlation coefficient was calculated. Samples having a correlation coefficient of R&lt;0.89 with respect to the majority were treated as out-liers and were excluded for further analysis. The intensity of each clone in one particular nucleus was subsequently further defined as the median of intensities of that clone in remaining qualified samples in that nuclei. The resulting intensity matrix (N×M) (N: number of clones; M: number of sample types) was further normalized (spline normalization) so that the distribution of the intensities of all the clones for each individual sample type was fitted to a smooth cubic B-spline. The spline normalization could reduce abnormality in the distribution of the intensities in particular samples caused by saturation in image processing.  
         [0092]    In addition to the 2147 clones, fifteen plant cDNA were printed on the same microarray. The intensities of these fifteen plant cDNAs were measured and processed in the same manner as other clones, and used as negative controls. The average intensity of the fifteen plant genes in all M types of samples was defined as background. Each clone was then classified as absent in a cell population if its medium intensity was below the three-fold of the background; or as present if its medium intensity was three-fold above the background. Hierarchical clustering was generated by using Cluster software (Stanford).  
         [0093]    Gene Expression Profiling of Brain Nuclei is Reproducible.  
         [0094]    Gene expression profiles were measured from seven different laser-captured brain nuclei in six different groups of rats (i.e. control/vehicle, CMS/vehicle, control/imipramine, CMS/imipramine, control/ novelR1, CMS/novelR1). To estimate experimental reproducibility within a group of rats, the pair-wise similarities of gene expression profiles were compared by calculating a linear correlation coefficient (FIG. 3). The average linear correlations coefficients (R) within one region ranged from 0.955 to 0.978 (n =3 to 5 per group, FIG. 3 a ). For examples, the correlation value for the DR in control/vehicle animals ranged from 0.95 to 0.98 (FIG. 3 b ). For CA3 the R values ranged from 0.96 to 0.98. These data suggest that the brain nuclei were clearly captured and that these nuclei are relatively homogenous in gene expression.  
         [0095]    Different Brain Nuclei Have about 4% to 7% in Unique Gene Expression.  
         [0096]    To further validate the LCM/cDNA microarray approach, the gene expression patterns of the seven laser-captured brain nuclei were compared within the control/vehicle groups (FIG. 4). Of the 2137 genes (unique mRNAs) analyzed, 871 (40.76%) gave a hybridization signal consistent with a call of presence in at least one brain region according our criteria (i.e. at least three-fold above background level). The number of genes detected within one region ranged from 499 to 527 (FIG. 4 a ). The number of genes unique to one of the seven investigated brain nuclei, according our criteria for a call of presence, ranged from 21 to 43 (FIG. 4 a ). The highest number of unique genes (43) was found in LC. All 419 genes that changed expression levels between the different areas of the brain are listed in Table 5.  
         [0097]    To compare the overall gene expression patterns of the different brain areas two-dimensional hierarchical clustering was performed (FIG. 4 b ). Hierarchical clustering analysis showed similarities in expression patterns between the two divisions of the PVN and between the three regions of the hippocampus (FIG. 4 b ). For example, the dendrogram on the vertical axis shows that the two divisions of the PVN (PA and MG) were joined by a very short branch reflecting their similarities compared to the other areas (FIG. 4 b ) and the three regions of the hippocampus (CA1, CA3 and DG) were also located on a common branch. The LC was located on a different branch of the dendrogram, suggesting that this nuclei has the greatest difference in gene expression among the seven nuclei that were examined. This finding is consistent with the LC containing the highest number of genes that are enriched (described above).  
         [0098]    The analysis was further validated by the agreement of our findings with that of previously documented expression patterns for “signature” genes for specific brain nuclei (FIG. 4 c ). For example, in our study, abundant mRNA expression encoding vasopressin (GB:AI072073) and oxytocin (GB:M88355) were detected in PA and MG cells, but not detected in the other examined nuclei. This finding is in agreement with previous studies [Hallbeck, 1999 #359] [Burbach, 1987 #354] [Tohyama, 1998 #348]. Other striking examples included mRNAs encoding tyrosine hydroxylase (GB: M10244) and serotonin transporter (GB: AA819178) to the LC and DR respectively (FIG. 4 c ).  
                                                                                                                                                                             A   B       1       Name               2   neuropeptide   9174| UI-R-E1-fg-b-04-0-UI| AA955779| Rat galanin (a neuropeptide) mRNA, complete cds       3   neuropeptide   9168| UI-R-E1-fg-g-12-0-UI| AA955767| Rat mRNA encoding rat pre-prosomatostatin (isolated from a medullary thyroid carcinoma)       4       8723| UI-R-A1-ev-b-11-0-UI| AA926266| Rat VL30 element mRNA       5       8637| UI-R-E0-br-e-03-0-UI| AA866450|  Rattus norwegicus  interleukin-2 receptor beta chain (p70/75) mRNA, complete cds       6       8615| UI-R-A0-aj-e-08-0-UI| AA866381| Rat mRNA for hnRNP protein, partial       7   neuropeptide   8610| UI-R-A0-bm-a-06-0-UI| AA866347| Rat mRNA encoding rat pre-prosomatostatin (isolated from a medullary thyroid carcinoma)       8       8569| UI-R-A1-el-b-12-0-UI| AA926045| Similar to AF020760  H sapiens  serine protease (Omi) mRNA       9   apoptosis   8540| UI-R-A1-es-c-03-0-UI| AA926004|  Rattus norvegicus  mRNA for 14-3-3 protein eta-subtype, complete cds       10   ion channel   81| 832845| AA427267| SCN9a=PN1 Sodium Channel alpha, V-gated       11       7888| UI-R-A1-eg-b-04-0-UI| AA924903| Similar to HUMKG1C Human mRNA for KIAA0045 gene, mRNA       12   ion channel   786| UI-R-EO-bu-g-03-O-UI| AA875142| Rat 5HT3 receptor mRNA, complete cds       13       7732| UI-R-A1-dz-c-12-0-UI| AA924656| Similar to AB005298  H sapiens  BAI 2 mRNA       14       735| UI-R-E0-ck-e-08-0-UI| AA874900| Similar to AC004021 kelch protein       15       7233| UI-R-A1-dp-d-03-0-UI| AA901316|  Rattus norvegicus  DCoH gene       16       6980| UI-R-E0-dk-d-12-0-UI| AA900886| Similar to MMUBF Mouse ubf gene for transcription factor UBFmRNA       17       68| 775900| AA276133| CIC-2 Chloride Channel, V-gated       18       6611| UI-R-C0-hc-e-09-0-UI| AF020760| Omi       19   hsp   6565| UI-R-G0-UI-h-03-0-UI| L39370| Human Hsp27       20       6544| UI-R-C1-ke-c-01-0-UI| L28175| Prostaglandin EP2       21       6510| UI-R-E1-fu-h-10-0-UI| L11667| Human cyclophilin-40       22       6505| 2076313| L10284| Human calnexin       23       6457| 918411| D42055| hNEDD-4/KIAA0093, hect domain protein       24       644| UI-R-E0-cq-c-04-0-UI| AA875241| Similar to MMUBCM4GN  M. musculus  UBcM4 mRNAmRNA       25   hsp   6439| 2064663| D13627| TCP-1 Hsp60, theta subunit       26       6407| 749025| M11723| Blood coagulation factor XII       27       6406| 660902| M112331 Cathepsin D       28       6351| UI-R-C0-IG-e-10-0-UI| M24898| Nuclear receptor alpha1 for thyroid horm       29   hsp   6332| UI-R-AD0-we-g-01-0-UI| M196451 Human BiP/GRP78/ER resident HSP70       30   GPCR   6296| 7006963431 M818301 Somatostatin (55R2)       31   G protein signaling   6240| 2088210| M60156| Go alpha (G-protein)       32       6232| 1152703| M58051| FGFR3       33   GPCR   6204| 700311648| U07225| Purinergic (P2U)       34       6150| UI-R-AE0-xe-f-02-0-UI| M94335| Akt1/PKB/RAC       35       6118| UI-R-CO-gs-d-06-0-UI| U39738| PAK3       36       6068| UI-R-AA1-aab-c-10-0-UI| U20553| P57       37       60664| 583865| U20372| Calcium channel beta 3 (CCHB3); V-gat,aux       38   proteasome   6031| 478404| W07641| ubiquit.-like protein SMT3B (SUMO-1)       39   GPCR   5997| 701899983| U71092| GPCR37 (Orphan, public=GPR24)       40       5981| 1885026| U59167| Desmin       41   ion channel   5977| 700254854| U57352| ASIC2=MDEG=BNC1 brain Na chan; amil sens       42   5958| 947959| U47036| CCR5       43   GPCR   5957| UI-R-Y0-acc-e-12-0-UI| U469231 GPCR8 (Orphan, public)       44   hsp   5934| 464942| X63368|  H. sapiens  HSJ1 mRNA, DnaJ homolog       45   ion channel   5897| UI-R-Y0-aci-c-12-0-UI| X16476| Kv2.1=DRK1 potassium channel; V-gated       46   hsp   5889| UI-R-A0-ab-h-12-0-UI| X15187| Human gp96/GRP94, ER HSP90       47   5873| 1211032| X04434| IGF1R       48   5855| 701644254| Z30425| Nuclear receptor/orphan MB67/CAR       49   ion channel   5845| 493098| Y07521| Kv3.1a=NGK2 potassium channel; V-gated       50   transcription factor   5844| 944489| Y00864| SCFR/c-kit       51       5832| 677053| X99585| ubiquit.-like protein SMT3B (SUMO-1)       52   GPCR   5825| 701293873| X94552| Glutamate metabotropic (mGlu7)       53       5824| 2182578| X92106| Bleomycin hydrolase       54       5821| 700230143| X89576| Matrix metalloproteinase MT2-MMP       55       5814| 368357| X85237| splicing factor SF3a120       56       5809| 316104| X82153| Cathepsin K       57   hsp   5789| UI-R-C0-hc-d-08-0-UI| X74801| Human TCP-1 HSP60, gamma subunit       58   apoptosis   5763| 100400| 100400| 14-3-3 gamma       59   GPCR   5704| 701035392| 258| H3 Histamine Rec (GPCR97)       60   apoptosis   5694| 95332| 95332| 14-3-3 eta       61       5681| 112173| 112173| calcineurin A2       62       4716| 583498| AA142680| S50200 S50200 dopamine beta-hydroxylase [mice, Genomic/mRNA, 2274 nt]. Blastn P. = 4.6E-167       63       4715| 580798| AA139498| L41351 HUMPROS  Homo sapiens  prostasin mRNA, complete cds. Blastn P. = 2.5E-141       64       4699| 604709| AA161790| X05026 HSRHOB Human rho mRNA (clone 12). Blastn P. =1.5E-204       65       4262| 577610| AA426192| hUBC6       66       39517| UI-R-AG0-ww-b-07-0-UI| U63421| sulfonylurea rec (SUR1)       67   transcription factor   39504| UI-R-01-kw-b-11-0-UI| AF012923| Wig-1       68       394961UI-R-AD1-zn-f-05-0-UIIU438441cyclinD3gene       69       39495| UI-R-02p-nz-g-03-0-UI| U28789| PACT       70   polyamine synthesis   39494| UI-R-Y0-acv-f-12-0-UI| J04791| DCOR       71       39490| UI-R-C0-jh-b-10-0-UI| Y14296| BTEB-1       72   transcription factor   39485| UI-R-C0-is-f-03-0-UI| X17163| c-jun       73       39477| UI-R-E1-gf-e-12-0-UI| Y07701| cytosol alanyl aminopeptidase       74       39475| UI-R-C3-ti-d-08-0-UI| Y07836| helix-loop-helix prot       75   apoptosis   39461| UI-R-C0-jq-f-07-0-UI| AF022223| BAG-1       76       39460| UI-R-Y0-abk-h-03-0-UI| U77615| crx homeodomain prot       77       39456| UI-R-AE0-xm-h-07-0-UI| AFO31384| TWIK-related acid-sens K+ channel (TASK)       78   GPCR   39452| UI-R-C2-nh-f-03-0-UI| X51585| Adrenergic alpha1B Rec       79       39451| UI-R-C2-mq-h-08-0-UI| U23781| A1-d prot       80       39428| UI-R-E0-cd-a-02-0-UI| D29678| CDKS       81       39424| UI-R-C0-jh-c-05-0-UI| U28068| neuroD       82   GPCR   39418| UI-R-Y0-mj-a-06-0-UI| M58316| Adrenergic alpha2C Rec       83       39416| UI-R-E0-de-a-06-0-UI| U1326| methionyl aminopeptidase II       84       39413| UI-R-A1-eg-e-06-0-UI| M62867| MSY-1       85       39404| UI-R-C2p-qw-a-08-0-UI| M31178| calbindin D28       86       39402| UI-R-AF1-aaq-g-02-0-UI| D76432| EF1 delta       87       39401| UI-R-BT0-qa-h-12-0-UI| U64828| SRC-1       88       39394| UI-R-C3-ty-c-12-0-UI| X15052| NCAM-140       89   transcription factor   39392| UI-R-G0-uh-h-09-0-UI| AF062566| Sp1       90   proteasome   39370| UI-R-E0-bv-f-08-0-UI| D26598| proteasome beta 3 subunit       91       39365| UI-R-E0-bv-d-02-0-UI| D29011| proteasome catalytic subunit 3       92       39358| UI-R-C2p-nt-b-07-0-UI| X65227| NMZ1       93   GPCR   39356| UI-R-AA1-aaa-d-04-0-UI| U15280| Oxytocin Rec       94   GPCR   39351| UI-R-C0-jn-c-07-0-UI| X97121| Neurotensin 2 Rec       95       39334| UI-R-C2p-ns-f-01-0-UI| U88716| Nkx-32 homeodomain prot       96   proteasome   39323| UI-R-E0-cy-e-09-0-UI| D00761| proteasome beta 1 subunit       97   prtoeasome   39321| UI-R-AC1-xw-f-06-0-UI| AF079564| ubiquitin carboxy-terminal hydrolase ubp41       98   transcription factor   39311| UI-R-C1-lq-e-10-0-UI| J04509| JUN-D prot       99       39296| UI-R-C2p-rc-d-02-0-UI| U19597| Cdk4/Cdk6 inhib prot       100       39290| UI-R-C1-kc-d-10-0-UI| U41741| MMUSF (USF)       101       39281| UI-R-C1-kb-d-12-0-UI| AF005885| cyclin G2       102   transcription factor   39274| UI-R-C0-hv-a-09-0-UI| AF065386| Jab1       103       39265| UI-R-Y0-ach-h-07-0-UI| X91753| SEF2       104   polyamine synthesis   39260| UI-R-AC0-yp-f-08-0-UI| D10706| OAZ       105       39254| UI-R-C2p-oh-h-09-0-UI| D29956| UBPY ubiquitin isopeptidase ( H. sapiens )       106       39253| UI-R-C2p-ro-d-11-0-UI| AF017182| Sox10       107       39252| UI-R-C0-il-c-03-0-UI| U42556| freac-1 gene       108   proteasome   39236| UI-R-C3-tr-c-02-0-UI| S71381| proteasome beta 4 subunit       109       39212| 101689| 101689| Mouse transcriptional regulator RPD3 homolo       110       39209| 80164| 80164| Rat heavy neurofilament polypeptide NF-H       111       39195| 95418| 95418| Rat non-muscle myosin alkali light chain       112       39192| 476493| M97200| krueppel-like factor       113       39191| 700295357| M92340| IL6B       114       39175| 80186| 80186 Novel       115       39149| 102883| 102883 Novel       116       39140| 701293538| M21948 dihydropyridine-sens Ca channel alpha-2 sub       117       39133| 111979| 111979| Novel       118       39132| 701900803| M81886| glutamate rec type I (HBGR1)       119       39112| 872080| M26745| IL6       120       39111| 100756| 100756| Novel       121       39109| 109519| 109519| Rat PKG binding protein and substrat       122   ion channel   39094| 700771408| L08494| GABA-A receptor       123       39092| 113323| 113323| Rat light molecular-weight neurofila       124       39091| 112184| 112184| Novel       125       39083| 113568| 113568| Mouse neurofilament protein (NF-L) gene, 3′ flank       126       39075| 100749| 100749| Mouse transcriptional regulator RPD3 homolo       127       39068| 112215| 112215| retrovirus-related leucine zipper protein p40 - ra       128       39062| 700773553| AJ225124| hyperpolarization-act cation channel HAC3       129       39058| 112959| 112959| Novel       130       39057| 571654| X61506| E46 for E46 prot       131       39055| 112214| 112214| S-100 beta subunit [rats, Genomic, 423 nt, segment       132       39053| 112025| 112025| Rat ID-A element in the S-100 beta-subunit gene.       133       39049| 101164| 101164| P46783 Human 40s ribosomal protein       134       39025| 1366563| X51405| carboxypeptidase H       135       38988| 700183273| M10244| tyrosine hydroxylase       136       38987| 1972427| D14425| calcineurin       137       38986| 111692| 111692| Novel       138       38973| 113308| 113308| Rat light molecular-weight neurofilament       139       38971| 109491| 109491| Human MUM2 gene       140   apoptosis   38967| 1211267| U67885| p53 binding prot 1       141       38960| 113236| 113236| Rat myelin proteolipid (PLP)       142       38956| 95821| 95821| P09896 Human       143       38955| 95395| 95395| Rat light molecular-weight neurofilament       144       38592| 80905| 80905| Novel       145       38946| 103913| 103913| Novel       146       38945| 95793| 95793| Rat cytoplasmic dynein heavy chain       147       38941| 111147| 111147| Mouse B2 repeat in the 3′ flank of protein 53 (p53       148       38933| 1448814| M25889| Mylein basic port       149   GPCR   38929| 700148588| X66842| Serotonin 2B Rec       150       38922| 41932| U12194| voltage-gated Na+ channel beta-1 sub (SON1B) gene       151       38921| 700280626| S76145| Na/Cl dep neurotransmitter transporter       152       38917| 1364912| U36393| TFEB       153       38916| 477909| U68384| Mrg1b       154       38910| 112963| 112963| Mouse mitochondrial genes coding for three transfe       155       38909| 101166| 101166| Mouse neurofilament protein (NF-L) gene, 3′ flank.       156       38898| 106216| 106216| Horse serpin mRNA, complete cds.       157       38894| 100750| 100750| Sequence 1 from patent U.S. Pat. No. 5457026.       158       38884| 112218| 112218| S-100 beta subunit [rats, Genomic, 423 nt, segment       159       38879| 112228| 112228| Mouse TGF-beta-inducible protein (TSC-36) m       160       38875| 84488| 84488| Novel       161       38865| 1297351| M26657| germinal peptidyl-dipeptidaseA       162   proteasome   38863| 633539| D00763| proteasome alpha 4 subunit       163       38856| 463999| U63858| U57939       164       38845| 84487| 84487 Novel       165       38838| 101073| 101073| Rat PAG608 gene       166       38833| 1210758| AF057691| TCF-3       167       38829| 108622| 108622| ribosomal protein S24 homolog {clone 2-6} [rats, r       168   ion channel   38824| 679093| AF052746| chloride channel CaCC       169       38822| 103933| 103933| Rat gene for testicular cell adhesio       170       38816| 113570| 113570| Novel       171   apoptosis   38808| 111644| 111644| Rat RNA-binding protein SiahBP mRNA,       172   GPCR   38793| 701472025| M64236| Neurokinin 1 Rec       173   GPCR   38789| 402354| AF0279551 GPR27 Rec       174       38787| 111636| 111636| Novel       175       38783| 1211735| Y10926| RBP-L       176       38779| 95446| 95446| Mouse brain mRNA.       177       38772| 1162568| Y076881 NfiX gene       178       38768| 101714| 1017141 Novel       179       38764| 101216| 101216| Bos taurus ribosomal protein 52 mRNA, partial cds.       180       38761| 100721| 100721| Novel       181   proteasome   38756| 100763| 100763| P11661 Rat nadh-ubiquinone ox       182   neuropeptide   38737| 701905916| M10088| dynorphin       183   G protein signaling   38729| 95348| 95348| GTP-binding protein rab10 - rat       184       38725| 102725| 102725| Novel       185   ion channel   38721| 700247271| L08495| GABA receptor alpha6       186   GPCR   38716| 701031976| X63574| Somatostatin 3 Rec       187       38714| 112210| 112210| Mouse LB9 gene, partial sequence.       188       38712| 669616| U89412| PML isoform 1       189       38711| 716499| U90724| X-Proaminopeptidase(eukaryote)       190   GPCR   38710| 700369402| L14618| Calcitonin Rec       191       38701| 1331673| M11597| CGRP alpha       192       38694| 112194| 112194| Novel       193       38676| 701896910| M36418| GLR1       194   GPCR   38675| 701901569| M99376| Adrenergic alpha2C Rec       195       38667| 111664| 111664| Human (clone hh18) protein tyrosine phospha       196       38664| 700133895| 038450| 954 Rec       197       38663| 701921173| M64752| glutamate rec sub (GluH1)       198       38653| 106117| 106117| Novel       199       38623| 113304| 113304| Rat light molecular-weight neurofilament       200       38621| 444406| 444406| Novel       201       38614| 111621| 111621| Novel       202       38605| 108620| 108620| Rat receptor for hyaluronan-mediated       203       38602| 101693| 101693| Mouse ribosomal protein (ke-3) gene, exons       204       38601| 100748| 100748| Mouse transciptional regulator RPD3 homolo       205       38594| 113748| 113748| Mouse necdin mRNA, complete cds.       206   ion channel   38582| 700773668| M81253| Kv3.4 gene       207       38577| 113515| 113515| Novel       208       38558| 66940| 66840| Novel       209       38546| 96780| 96780| Bos taurus clone CSSM015 microsatellite DNA sequen       210       38545| 101138| 101138| Rat ribosomal protein S24       211       38536| 111254| 111254| Human C14orf3 protein       212       38533| 475889| AF020198| PBX2       213       38532| 103937| 103937| Rat heavy neurofilament (NF-H) polypeptide, partia       214       38528| 112216| 112216| S-100 beta subunit [rats, Genomic, 423 nt, segment       215       38522| 463924| T67463| other peptidase (C1A)       216       38508| 66531| 66531| Novel       217       38504| 84486| 84486| Novel       218       38491| 108519| 108519| Rat gamma-smooth muscle isoactin pro       219       38487| 112021| 112021| Rat brain ID transcript, clone bBC2-       220       38469| 95406| 95406| Rat light molecular-weight neurofilament       221       38463| 113514| 113514| Novel       222       38417| 79183| 79183| Novel       223       38404| 1039810| AA297071| Similar to N-methyl-D-aspartate glutamate receptor       224       38402| 701289315| X99792| capacitative Ca entry channel 1       225   ion channel   38386| 700495245| L08493| GABA-A receptor       226       37466| 386514| W65013| Similar to X07384 GLI PROTEIN.       227       37464| 386559| W65005| Mouse cDNA clone IMAGE:386559 5′       228       36393| 387565| A18932401 Similar to L14935 Mouse neural retina-specific leucine zipper protein.       229   ion channel   33| 426170| AA002993| Potassium channel Kv3.4a (Raw3), V-gated       230       2319| UI-R-A0-af-e-06-0-UI| AA817907| Similar to MUSCDPK mouse cyclin-dependent kinase homologue (p130PITSL) mRNA, complete cdsmRNA       231       21709| UI-R-AF0-ya-b-04-0-UI| 988064T6| LVENNOT03 INCYTE       232       21692| UI-R-AC1-xn-e-07-0-UI| 817852H1| OVARTUT01 INCYTE       233       21664| 903057| 580795H1| NMDA channel-like       234   DNA repair   21573| 1054114| 3764982H1| human homologue of yeast RAD23       235   DNA repair   21458| UI-R-E0-ci-a-06-0-UI| 2583919H1| human homologue of yeast RAD23       236       21418| 1348327| 2049923H1| LIVRFET02 U43892 g1 167981 Mouse ABC transporter-7 mRNA, partial cd gb103rod 83 -55       237   DNA repair   21304| 420048| 1676240T6| cell cycle checkpoint rad9 gene       238       21251| 975800| 1275842F6| Eph-Erk       239   ion channel   21230| 748734| 2658404T6| SK2 calcium-activ potassium chann homolo       240       20977| UI-R-02p-np-g-01-0-UI| 485639T6| retinoic acid hydroxylase hP450RAI       241       20971| 2182407| 3369279H1| LON; ATP-Dep Proteas LA       242       20768| 96782| 96782| M58405  R. norvegicus  thymosin beta-10 gene, complete cds. 1.0e-72       243       20765| 95816| 95816 X51396 Mouse MAP1B mRNA for MAP1B microtubule-associated 6.5e-99       244   axon outgrowth   20763| 95791| 95791| M16228 Rat neuronal growth protein 43 (GAP-43) mRNA, comp 9.7e-187       245       20762| 95494| 95494| M93056 Human mononcyte/neutrophil elastase inhibitor mRNA 1.9e-117       246       20760| 95467| 95467| U43747 Human frataxin (FRDA) mRNA, complete cds. 1.9e-107       247       20759| 95416| 95416| S77858 non-muscle myosin alkali light chain [rats, Spragu 2.9e-92       248   hsp   20754| 95386| 95386| M11942 Rat 70 kd heat-shock-like protein mRNA, complete c 9.0e-108       249       20751| 95321| 95321| G27093 human STS SHGC-31976. 1.5e-91       250       20749| 95308| 95308| S82024 SCG10=neuron-specific growth-associated protein/st 4.4e-102       251       20748| 94433| 94433| Z92839 Caenorhabditis elegans cosmid T08D2, complete sequ 0.89       252       20743| 84483| 84483| AC003043  Homo sapiens  chromosome 17, clone HRPC1067M6, comp 2.9e-31       253   energy production   20740| 83925| 83925| X02231 Rat mRNA for glyceraldehyde-3-phosphate-dehydrogen 7.9e-210       254       20739| 83922| 83922| 569874 C-FABP=cutaneous fatty acid-binding protein [rats, 6.0e-194       255       20738| 83912183912| L37086  Homo sapiens  FK-506 binding protein (fkbp12.6) gen 1.9e-151       256       20726| 82552| 82552| D17296 Rat mRNA for polyubiquitin (ten completely repetit 5.4e-90       257       20724| 82519| 82519| M81225 Rat farnesyltransferase alpha subunit mRNA, comple2.7e-164       258       20720| 82475| 82475| V00681  R. norvegicus  mitochondrial genes for 16S rRNA, tRN 8.6e-82       259       20716| 82210| 82210| AF014955  Homo sapiens  TFAR19 mRNA, complete cds. 1.3e-70       260       20710| 82096| 82096| X14848 Rat ( R. norvegicus ) mitochondrial genome. 1.0e-99       261       2071| UI-R-AO-at-f-11-0-UI| AA818381| Similar to MMCKIT Mouse c-kit mRNAmRNA       262   axon outgroth   20709| 82094| 82094| X03369 Rat mRNA for beta-tubulin T beta15. 5.7e-105       263       20708| 82093| 82093| G15458 human STS SHGC-16876. 6.7e-51       264       20703| 82047| 82047| M71245 Rat prostatein C3 subunit gene, complete cds. 3.7e-36       265   proteasome   20694| 81776| 817761045249 Rat mRNA for proteasome activator rPA28 subunit al 1.4e-178       266       20693| 81773| 81773| X68273  M. musculus  mRNA for macrosialin. 1.0e-134       267       20690| 81743| 81743| X05608 Human gene for neurofilament subunit NF-L. 5.0e-38       268       20674| 80860| 80860| X95591  M. musculus  mRNA for C1D protein. 1.7e-77       269       20673| 80835| 80835| AC000083  Home sapiens  Chromosome 22q11.2 Cosmid Clone 68a1 0.65       270       20672| 80832| 80832| U16686  Rattus norvegicus  defensin RatNP-1 precursor mRNA, 2.9e-117       271       20669| 80637| 80637| X70369  R. norvegicus  mRNA for pro alpha 1 collagen type II 2.9e-81       272       20667| 80178| 80178| M58405  R. norvegicus  thymosin beta-b gene, complete cds. 6.1e-79       273       20665| 80157| 80157| D83407 ZAKI-4 mRNA in human skin fibroblast, complete cds 1.2e-59       274       20661| 80013| 80013| G27219 human STS SHGC-30611. 2.6e-60       275       20655| 79192| 79192| V00680 Rat mitochondrial genes coding for 16S and 12S rRN 1.7e-109       276       20654| 79184| 79184| J04517 Rat high molecular weight neurofilament (NF-H) pro 5.3e-141       277       20591| 66897| 66897| M80899 Human novel protein AHNAK mRNA, partial sequence. 1.3e-38       278       20590| 66886| 66886| U52828 Human Cri-du-chat region mRNA, clone NIBA2. 2.2e-75       279       20588| 66841| 66841| X51406 Rat mRNA for carboxypeptidase E (EC 3.4.17.10). 2.4e-167       280       20587| 66839| 66839| M15563 Human MHC class II HLA-DR-beta-1 pseudogene (DR7), 0.79       281       20583| 66706| 66706| M30952 Orangutan 28S ribosomal RNA gene fragment. 9.8e-151       282       20582| 66692| 66692| L81910  Homo sapiens  (subclone 3_c10 from PAC H74) DNA seq 0.00048       283       20581| 66688| 66688| U49099  Rattus nervegicus  cis-Golgi p28 (p28) mRNA, comle 6.8e-193       284       20568| 115932| 115932| M25638 Rat smallest neurofilament protein (NF-L) mRNA, pa 6.7e-157       285       20566| 115916| 115916| X62952  R. norvegicus  mRNA for vimentin. 2.8e-167       286       20563| 113752| 113752| AL021308 Human DNA sequence from cosmid U246D9 on chromosom 0.93       287       20562| 113749| 113749| M80840  M. musculus  necdin mRNA, complete cds. 1.7e-71       288       20557| 113571| 113571| D28875 Rat mRNA for osteonectin, complete cds. 2.2e-171       289       20550| 113529| 113529| M38194 Rat extracellular signal-regulated kinase 1 mRNA, 2.8e-203       290       20545| 113318| 113318| I00256 Sequence 7 from U.S. Pat. No. 4900811. 1.3e-191       291       20541| 113285| 113285| X76985  R. norvegicus  mRNA for latexin. 4.3e-171       292       20540| 113284| 113284| M23984 Rat mitochondrial proton/phosphate symporter mRNA, 2.7e-174       293   ion channel   20536| 113244| 113244| X15466 Rat mRNA for GABA(A) receptor beta-1 subunit. 7.3e-172       294       20532| 113167| 113167| AC002299  Homo sapiens  Chromosome 16 BAC clone CIT987-SKA-11 0.84       295       20530| 113155| 113155| U40933  Caenorhabditis elegans  cosmid F20D12. 0.38       296       20529| 113063| 113063| AC000399 Genomic sequence from Mouse 9, complete sequence. 6.5e-11       297       20520| 112951| 112951| AC002121 Genomic sequence from Mouse 11, complete sequence. 0.00031       298       20512| 112160| 112160| M14512 Rat Na+, K+-ATPase alpha(+) isoform catalytic subun 1.5e-259       299       20505| 111646| 111646| D28875 Rat mRNA for osteonectin, complete cds. 2.5e-206       300       20501| 111616| 111616| X58526| Mouse DNA for an L1 element. 1.3e-70       301       20500| 111613| 111613| M25888 Rat lipophilin mRNA, 3′ end. 4.4e-125       302       20496| 111441| 111441| U25844  Mus musculus  serine proteinase inhibitor (SPI3) mR 1.6e-134       303       20476| 109494| 109494| M38188 Human unknown protein from clone pHGR74 mRNA, comp 2.8e-84       304       20475| 109492| 109492| M26232 Rat peripherin gene, complete cds. 1.4e-1 39       305       20472| 109006| 109006| S80636 injury-inducible gene (ID repetitive element, clon 3.6e-07       306       20471| 109001| 109001| M89646  Rattus norvegicus  ribosomal protein S24 mRNA seque 1.6e-80       307       20468| 108618| 108618| L35240 Human enigma gene, complete cds. 2.5e-17       308       20467| 108615| 108615| X55572  R. norvegicus  Apo D mRNA. 9.0e-193       309       20464| 108534| 108534| X77953  R. norvegicus  mRNA for ribosomal protein S15a. 1.4e-68       310       20455| 106217| 106217| M20480 Mouse brain neurofilament-L mRNA, complete cds. 4.7e-122       311       20448| 106118| 106118| L10426  Mus musculus  ets-related protein 81 (2R81) mRNA, c 5.1e-48       312       20443| 105946| 105946| D83407 ZAKI-4 mRNA in human skin fibroblast, complete cds 5.8e-63       313       20434| 105919| 105919| X61294  R. norvegicus  L1 retroposon, ORF2 mRNA (partial). 1.5e-92       314       20430| 105905| 105905| D83783 Human mRNA for KIAA0192 gene, partial cds. 3.4e-05       315       20423| 105878| 105878| U13369 Human ribosomal DNA complete repeating unit. 0.021       316       20420| 105801| 105801| D17577 Mouse mRNA for kinesin-like protein (Kif1b), compl 2.5e-122       317       20419| 105787| 105787| X60370  R. norvegicus  mRNA for microtubule associated prote 1.2e-97       318       20416| 105774| 105774| U02983  Rattus norvegicus  secretogranin III (SgIII) mRNA, 9.0e-82       319       20412| 103932| 103932| M35826 Rat mitochondrial NADH-dehydrogenase (NDI) gene, c 2.0e-78       320   G protein signaling   20410| 103925| 103925| M12673 Rat guanine nucleotide-binding protein G-s, alpha 4.1e-66       321       20406| 103909| 103909| M13100 Rat long interspersed repetitive DNA sequence LINE 4.3e-172       322       20404| 103831| 103831| D90005 Rat endogenous retroviral sequence, 5′ and 3′ LTR. 4.8e-97       323       20403| 103830| 103830| M23953 Rat carboxypeptidase B gene, exons 6, 7, and 8. 1.1e-68       324       20401| 103821| 103821| D10699 Rat mRNA for ubiquitin carboxyl-terminal hydrolase 3.1e-99       325       20400| 103820| 103820| X60469  R. rattus  FE65 mRNA for adaptor protein interacting 3.0e-167       326       20396| 103801| 103801| AF043698  Caenorhabditis elegans  cosmid C54G6. 0.12       327       20395| 103795| 103795| X70369  R. norvegicus  mRNA for pro alpha 1 collagen type II 3.0e-69       328       20391| 103703| 103703| V01556 Rat mitochondrial genome fragment from Sprague-Daw 1.0e-188       329       20385| 102872| 102872| L40632  Mus musculus  epithelial ankyrin 3(7kb isoform) mR 1.6e-175       330       20379| 102748| 102748| M16597 Human cytochrome c1 mRNA, partial cds. 2.9e-127       331       20363| 101197| 101197| G05883 human STS WI-6610. 1.9e-65       332       20437| 101132| 101132| M89646  Rattus norvegicus  ribosomal protein S24 mRNA seque 6.2e-55       333   hsp   20343| 101112| 101112| M86389 Rat heat shock protein (Hsp27) mRNA, complete cds. 1.2e-147       334       20342| 101108| 101108| X75683  H. spaiens  (TL35) mRNA from LNCaP cell line. 1.0e-73       335       20340| 101083| 101083| X79064  V. unguicutata  (Red Caloona) AKCS9 mRNA. 0.041       336       20334| 100940| 100940| Z12152  R. norvegicus  mRNA for neurofilament protein middle 1.5e-206       337       20328| 100875| 100875| L01693 Rat peptidyiglycine alpha-amidating monooxygenase 3.2e-123       338       20322| 100839| 100839| X96487  B. taurus  mRNA, anonymous. 5.5e-09       339   prteasome   20321| 100836| 100836| M29859 Rat proteasomes C2 component mRNA, complete cds. 1.0e-100       340       20317| 100759| 100759| M29341 Rat brain glyceraldehyde-3-phosphate dehydrogenase 2.8e-103       341   apoptosis   20308| 100704| 100704| D17614 Rat mRNA for 14-3-3 protein theta-subtype, complet 3.9e-228       342       20307| 100574| 100574| M22012  Mus musculus  synaptosomal associated protein 25 (S 4.3e-72       343       20306| 100573| 100573| L27153 Mouse kinesin heavy chain (Khcs) mRNA, 5′ end. 1.0e-81       344       20302| 100557| 100557| U80954  Caenorhabditis elegans  cosmid T07F8. 0.84       345   axon outgrowth   20301| 100465| 100465| X03369 Rat mRNA for beta-tubulin T beta15. 7.3e-91       346       20300| 100463| 100463| X62952  R. norvegicus  mRNA for vimentin. 1.2e-114       347       20298| 100455| 100455| U62800 Human cystatin M (CST6) mRNA, complete cds. 8.9e-91       348       20296| 100438| 100438| A08267 Nucleotide sequence for  P. falciparum  RMA-1 gene. 0.87       349       20295| 100437| 100437| S69874 C-FABP=cutaneous fatty acid-binding protein [rats, 6.7e-160       350       20272| 1065569| Z33905| nicotinic acethyicholine receptor associated 43 kD protein       351       20264| 917438| Z26634| ankyrin brain variant, ANKB       352       20258| 1260365| Z21876|  H. sapiens  X-linked ALD gene.       353   GPCR   20238| 700123692| Y10148| NTR2 receptor       354       20204| 613665| X96427| Homol. to ScUBC9       355       20127| 921632| X69292| myosin heavy chain. Cell Type:smooth muscle Tissue Expression: GI wall, Respiration       356       20080| 1497875| X61615|  H. sapiens  mRNA for leukemia inhibitory factor (LIF) receptor       357       20055| UI-R-C1-kp-d-10-0-UI| X57748f properdin       358       20029| 700247749| X54673|  H. sapiens  GAT1 mRNA for GABA transporter       359       20027| 1244915| X54297| Human mRNA for histidine decarboxylase (EC 4.1.1.22)       360       19976| 700247354| X1S376| Human mRNA for GABA-A receptor, gamma 2 subunit       361       19960| 700247209| X14767| Human mRNA for GABA-A receptor, beta 1 subunit       362   transcription factor   19941| UI-R-BT0-pm-c-04-0-UI| X12740| C-Jun of the transcription factor AP-1       363   neuroptide   1986| UI-R-A0-au-d-10-0-UI| AA818532| Rat gamma-preprotachydinin A mRNA, complete cds       364   neuropeptide   19136| 315382| W12030| U10071 RNU10071  Rattus norvegicus  CART protein mRNA, complete cds. Blastn: P. = 8.5e-117       365   proteasome   18970| 931025| U75362| ubiquitin carboxy terminal hydrolase       366   growth factor   18954| UI-R-Y0-mo-d-05-0-UI| U66198| fibroblast growth factor, FGF13       367   apoptosis   18941| 1050567| U59746| Bcl-w       368       18937| UI-R-AG0-xc-h-06-0-UI| U58522| huntingtin interacting protein       369   proteasome   18904| 407454| U44839| A ubiquitin C-terminal hydrolase       370       18871| 700128068| U33267| Human glycine receptor beta subunit (GLRB) mRNA, complete cds       371       18862| 803318| U30509| Gamma Glu Tranterase       372       18856| UI-R-C1-lp-e-07-0-UI| U28807| NFATc3       373       18835| 789552| U20240| CCAAT enhancer binding protein gamma       374   GPCR   18815| 700498633| U16129| Glutamate receptor (GluR4)       375       18784| 1617912| U08107| HSU08107 Human N-methyl-D-aspartate receptor subunit splice variant hNR1N (GRIN1) mRNA, partial cds.       376       1824| UI-R-A0-ar-f-11-0-UI| AA818840| Similar to MMU75839 mouse interferon regulatory factor 3 (mirf3) mRNA, alternatively spliced, complete cdsmRNA       377       18104| 1039340| M9S106| CREB-1       378   neuropeptide   18088| 640127| M88355| MUSOXYNEUI Mouse oxytocin-neurophysin I gene, complete cds.       379       18037| UI-R-C3-ss-b-09-0-UI| M737461  Homo sapiens  lutropin/horiogonadotropin reeptor (LHCGR) mRNA, complete cds.       380       17418| UI-R-Y0-acb-c-12-0-UI| R60006| HUMEAR17A Human trilodothyronine recptor (THRAI, ear1), and ear2 genes, last 2 exons each. BLASTN P. 2.8E-96       381       1571| UI-R-A0-bc-d-07-0-UI| AA819345| Rat parvalbumin mRNA, complete cds       382       14951| 700861309| M59980| K Channel       383       14925| UI-R-C0-ie-h-11-0-UI| M55040| Human acetylcholinesterase (ACHE) mRNA, complete cds       384       14871| 492525| M29871| Human ras-related C3 botulinum toxin substrate (rac) mRNA, complete cds       385   G protein signaling   14870| UI-R-E0-da-b-11-0-UI| M29870| Human ras-related C3 botulinum toxin substrate (rac) mRNA, complete cds       386       14866| UI-R-AA0-wp-c-07-0-UI| M29548| Human elongation factor 1-alpha (EF1A) mRNA, partial cds.       387       14866| 299720| M29548| Human elongation factor 1-alpha (EF1A) mRNA, partial cds.       388   axon outgrowth   14839| 338087| M25667| Human neuronal growth protein 43 (GAP-43) mRNA, complete cds       389   G protein signaling   14829| UI-R-C1-lh-b-02-0-UI| M23612| Human GTPase-activating protein (GAP) mRNA, complete cds       390       14817| 349760| M21571| Human platelet-derived growth factor (PDGFA) A chain mRNA.       391       14739| 700124548| L76224|  Homo sapiens  NMDA receptor mRNA, complete cds       392       14727| 1162580| L42198| MUSALOX  Mus musculus  arachidonate 5-lipoxygenase (Alox5) gene, complete cds.       393       14677| 1066814| L16510|  Homo sapiens  cathepsin B A cysteine protease associated with tumor invasiveness and neovascurlarisati       394   GPCR   1467| UI-R-A0-an-d-02-0-UI| AA819622| Rat G-protein coupled thrombin receptor mRNA, complete cds       395   neuropeptide   14620| 482891| K01911| Human neuropeptide Y (NPY) mRNA, complete cds       396       13845| 963216| H58254| monocyte chemoattractant protein 1 receptor (MCP-1RA)       397       13310| 602816| D86323| D86323  Mus musculus  mRNA for calmegin, complete cds.       398       13304| 1246629| D83004| similar to Drosophila bendless gene       399   proteasome   13275| UI-R-E0-ct-g-08-0-UI| D23662| ubiquitin-like protein       400       13165| UI-R-BT0-qi-f-04-0-UI| AI145577| Rat degenerin channel MDEG mRNA, complete cds       401   hsp   1278| 1246430| AA823192| D49547 HUMHSP40 Human mRNA for heat-shock protein 40, complete cds. Blastn P. = 3.5E-167       402       12712| UI-R-C2-nf-c-01-0-UI| AI072073| Rat vasopressin mRNA, complete cds       403   G protein signaling   12702| UI-R-C2-nh-g-02-0-UI| A1071860| Rat regulator of G-protein signalling 14 (RGS14) mRNA, complete cds       404       12681| UI-R-C2-my-e-04-0-UI| A1071179| Rat mRNA for cyclinG-associated kinase, complete cds       405       12678| UI-R-C2-ms-b-07-0-UI| AI071095| Rat vgr mRNA       406       1266| UI-R-AO-aq-c-10-0-UI| AA819897| Rat synuclein 1 mRNA, complete cds       407   ion channel   12538| UI-R-C1-kp-b-07-0-UI| AI058645| Rat Kv4.3 potassium channel mRNA, complete cds       408   neuropeptide   12490| UI-R-C1-iz-a-09-0-UI| AI045437| Rat neuropeptide Y mRNA, complete cds       409       12463| UI-R-C1-kd-e-12-0-UI| AI044870|  R. norvegicus  mRNA for elongation factor 1 alpha       410       12448| UI-R-C1-kc-c-05-0-UI| AI044610| Rat dopa decarboxylase (DOC) mRNA, complete cds       411       12427| UI-R-C1-kb-b-03-0-UI| AI044262| Rat mRNA for thyrotropin releasing hormone receptor, complete cds       412       12350| UI-R-C0-ib-c-02-0-UI| AI030286| Rat brain-derived neurotrophic factor (BDNF) mRNA, complete cds       413       12318| UI-R-CO-iy-b-07-0-UI| AI029599| Rat mineralocorticoid receptor (MR) mRNA, complete cds       414       12263| 659316| AF075599| conjugating enzymes       415   ion channel   12260| 700254638| AF064876| BCNG-1 hyperpolarization NSC channel=HCN1 = HAC2       416   proteasome   12223| UI-R-C1-kt-f-03-0-UI| AF022789| ubiquitin hydrolyzing enzyme I       417       11788| UI-R-C0-ho-b-04-0-UI| AA997314| Rat cDNA clone UI-R-C0-ho-b-04-0-UI 3′ mRNA       418   proteasome   1038| UI-R-E0-cj-b-04-0-UI| AA859300| Rat proteasomes C2 component mRNA, complete cds       419   proteasome   1031| UI-R-E0-cd-c-03-0-UI| AA859229|  Rattus norvegicus  ubiquitin conjugating enzyme mRNA, complete cds                        C   D   E   F   G   H   I   J   K       1   CA1.CMS   CA1.IMP   CA1.IMPnCMS   CA1.JRF   CA1.JRFnCMS   CA3.CMS   CA3.IMP   CA3.IMPnCMS   CA3.JRF               2   1   1   1   1   1   1   1   1   1       3   1   1   1   1   1.135106383   1   1   1   1       4   1   1.026595745   1.069148936   1.109148936   1.159787234   1.053803876   1.536399576   1.540545753   1.389933468       5   1.283765785   1.117871942   1.152476322   1.417151736   1.500295975   1.098971902   0.830980194   0.88179679   0.923074768       6   0.985121588   1.016195517   1.146686505   1.191468085   1.299080465   1.229552015   1.146405788   0.918101144   1.264264585       7   1   1   1   1   1.154787234   1   1   1   1       8   0.918237765   1.515092312   1.8366709   2.101396894   1.508840481   0.833539644   0.862206007   0.926900775   0.864616587       9   1.271983351   1.490840538   1.058110556   1.17292499   1.134983235   1.184266024   0.98016667   0.86311757   1.142719482       10   0.786262347   0.879611818   1.108889705   1.083839454   1.490824994   0.867116391   1.20458322   1.08546415   1.020460802       11   1.277605055   1.843345703   1.294554207   1.527329255   1.789088356   1.071466291   0.968051399   0.937863052   1.243531068       12   0.580658633   0.857415583   0.803006801   0.723660661   0.930258919   0.927113703   0.854713314   1.140751539   1.097910593       13   0.760842082   0.967954708   1.158522509   0.800087946   0.68949596   0.778530809   0.868427203   0.784918595   0.732258316       14   1   1.955319149   1.436808511   1.609787234   1.482234043   1   1.249255311   1.294361702   1.601808511       15   1   1   1   1   1   1   1   1   1       16   1   1   1.083085106   1   1   1   1   1   1       17   1.68533171   1.843919659   1.306025563   1.025562995   0.761412051   1.042526807   0.870960683   1.147676709   0.991100737       18   0.918452657   1.022825294   1.167341251   1.187777852   1.200384845   1.010731303   1.033229741   0.934244873   0.893184172       19   1.031509395   0.932438571   1.124055338   0.858145777   1.115713401   0.971141137   0.83235423   0.850822441   0.850712293       20   1   1   1   1   1   1   1   1   1       21   1.330920372   1.107606572   1.370217166   1.141388027   1.355883029   1.197396918   1.041212021       22   1.001916525   1.729840999   1.175042589   1.122373651   1.216283362   0.8854339   1.01981501   1.018987818   0.797337946       23   1.168235333   0.868461614   0.829895386   0.880070836   0.817892631   1.282736246   1.151929311   1.217781459   0.648857596       24   0.806988969   1.21877545   1.287776708   1.377952173   1.213148738   0.896036998   0.983004963   1.312265002   0.995262445       25   1.548089532   1.22034818   1.203527018   1.708161881   1.663124576   1.102383239   1.001680874   1.09205787   1.264227398       26   1   1.348191489   1.561276596   1.589361702   1.994787234   0.859468723   0.972812963   0.773545221   0.775103217       27   1.128055186   0.937950837   0.853841305   0.756985783   0.825232859   0.972462265   0.848513654   0.910617583   0.784796636       28   1   1.147340426   1.153297872   1.194255319   1.194361702   1   1   1   1       29   0.929867332   1.0147409   1.260800544   1.333484522   1.522678308 0.83777447   0.778861183   0.844324525   0.689691105       30   1   1   1   1.025   1   1   1   1   1       31   1.113756425   0.948850657   1.197387207   1.197208738   1.221159338   1.064588104   1.141800247   0.889935999   0.918677705       32   1.001651053   0.972291016   0.96317433   1.059976311   0.713398658   0.927060922   1.004460303   0.816130556   0.828514457       33   0.915764112   0.499164687   0.602538896   0.708686116   0.673568888   0.884301786   1.584374032   1.231258816   1.503423126       34   0.707739249   1.05150544   1.265663679   1.446508415   1.305367389   0.958500813   0.900369795   1.187684227   0.844704075       35   1.045635922   1.026555979   1.459111131   1.488602486   1.335229097   0.89865223   1.152229878   1.020670856   1.020784432       36   0.908402292   1.832463399   1.196721833   1.174633991   1.095798854   1.068026865   1.253434415   1.775770835   1.577592348       37   1.113297872   1.338085106   1.106489362   1.1752127661   0.853193351   1.20962379   1.209623797   1.035053952   0.86573345       38   0.942528893   0.933867927   0.855850933   1.025504768   0.825086746   1.132523583   1.276845591   1.315607869   0.995005148       39   1   1.016489362   1.344042553   1.98   1.780212766   1   1   1   1       40   1   1.036595745   1   1   1   1   1.059574468   1   1       41   1   1.036595745   1   1   1   1.030212766   1.249255319   1.164361702   1.174574468       42   0.928423354   0.98207757   1.330933625   1.296577588   1.274000226   0.982149165   1.018675082   0.981466218   0.847396557       43   0.971175085   1.263510529   1.663230747   2.063944927   1.958732145   1.007528423   0.938664374   1.229750645   0.800496799       44   1.205319149   1.418404255   1.882234043   1.958297872   1.946170213   1.118771009   1.02866073   1.150380374   1.142772896       45   1   1   1   1   1   1   1   1   1       46   1.694640812   1.304332372   0.958868133   1.026420757   0.89092058   1.539610003   0.876365457   0.585746033   0.952971924       47   0.806988969   0.966165692   0.875101799   0.891241578   0.886651366   1   1   1   1       48   0.808675141   0.578299043   0.655571572   0.466998646   0.66823921   1.209680851   1.279148936   1.128297872       49   1.00393617   1.378297872   1.120425532   1.146808511   1   1   1.225531915   1.056382979   1       50   0.977017638   0.970886912   0.804162606   0.68296287   0.822554784   1.20317521   1.095218057   0.937222647   1.197092578       51   0.847565517   0.91 4465052   0.857955956   0.990283343   0.852459307   0.896263683   1.098172552   1.211076264   0.840475257       52   1   1   1   1   10.841286042   0.979841796   0.955430807   0.852513396       53   1.303913818   1.909671325   1.164766256   1.036645988   0.906355098   1.062618209   1.006415724   1.339699611   1.61611348       54   0.757270603   0.967695158   1.006767099   1.0963506   1.91976154   0.925404696   0.975864081   0.871518157   0.85773662       55   0.992468022   1.104051685   1.37030063   1.268781248   1.541263554   0.860852567   1.014633884   1.063825972   0.885385843       56   1.534014194   1.104985286   1.897178466   1.681841786   1.43110611   1   1.162234043   1   1.19       57   1.112251548   1.075051591   1.611980015   1.387078672   1.433040078   1.300651235   0.838534071   1.051217998   1.360764155       58   1.228716794   1.700507317   1.103320224   1.328279653   1.77938274   1.21985654   1.040759567   0.719098387   1.170470526       59   0.855115112   1.433010213   1.505452657   2.118660204   1.800501991   1   1   1   1       60   1.412610123   0.900950078   0.74451546   0.867852824   0.806944205   1.325264926   1.402358755   0.86140869   0.801416797       61   1.311790816   1.256009503   1.151183145   1.493967053   1.302397549   1.074979172   1.44027581   1.548198417   0.847455568       62   1   1   1   1   1   1   1   1   1       63   0.672108555   0.643459133   0.567634899   0.538044631   0.730971059   0.812586363   0.48107104   0.695699919   0.606111076       64   1.270667179   1.072979725   0.870984273   0.858300503   0.724304154   1.350444203   1.495203492   1.335179564   1.241996588       65   1.116187147   1.111616026   1.030841624   0.808631353   0.772653939   1.086217209   1.216739298   1.1548744818   1.509356575       66   1.206040951   1.139644221   1.052407361   0.902093608   0.920496632   1.110717409   1.041554839   0.906094509   0.747896626       67   1   1.026595745   1.334361702   1.329255319   1.518297872   0.954445612   0.965428326   0.941457358   0.971158438       68   1.306231353   1.101972009   0.985058336   1.119193732   0.926674267   0.951589282   0.714795487   0.826509354   0.685423155       69   1   1   1   1   1   1   1   1   1       70   1.09787234   1.297978723   1.422021277   1.368510638   1.214148936   0.974358974   0.840080972   0.959598516   0.870023617       71   0.73667584   0.870033722   1.103647428   1.388193341   1.439610062   0.783437291   1.018781504   1.242893641   0.90936083       72   1   1   1   1   1   1.169861203   0.988323419   1.018873467   1.168465888       73   0.919550054   0.871412423   1.397149238   1.447961181   1.35868876   0.711905307   0.395935179   0.997628508   1.119926775       74   1.113297872   1.468617021   2.645851064   1.925957447   1.828191489   1   1   1   1       75   1   1   1   1   1   1.021626754   0.995885642   1.162253402   1.103597426       76   0.745266611   0.966697299   1.095951272   1.072977345   1.518375345   0.938618594   0.888933685   1.018425461   0.96207878       77   0.803854277   1.124274023   0.968585005   0.941789863   0.875065998   0.913779465   0.743553235   0.945420028   0.88482835       78   1   1   1   1   1   1   1   1   1       79   1   1.348191489   1.476276596   1.65106383   1.913829787   1.130332943   1.213485026   1.029780827   1.176008031       80   0.815993416   1.057197723   1.162334545   1.213839929   1.012207668   0.801179065   0.979343864   0.949282211   0.722469736       81   1   1.227659574   1.106489362   1.261382979   1.100851064   0.940328737   1.288229337   1.036690816   0.860091922       82   1.205319149   1.086914894   1.162659574   1   1   1   1   1   1       83   1.128723404   1.488723404   1.683404255   1.755425532   1.679893617   0.97835059   1.334226341   1.065744696   1.177829267       84   1.074490777   0.903780794   0.661228699   0.63659377   0.587068076   0.926811099   0.849338879   0.970202992   1.071450742       85   1.874702466   2.074645339   2.031705227   1.313624679   2.20384652   1   1   1   1       86   0.82265375   1.091805901   1.163259865   0.693965517   0.591317099   0.963163653   0.877351118   0.955191997   0.661595373       87   0.872390104   0.938709533   0.977100265   0.97539401   0.848816847   1.000695998   1.006512553   0.818493661   0.723738504       88   1.173070553   1.422932538   1.421055537   1.505299768   1.080269405   0.951358435   1.001411361   1.004082867   1.182015223       89   1   1   1   1   1.003829787   1   1   1   1       90   0.895325849   1.01030855   0.727458872   0.58253901   0.667372732   1.013615601   0.912508784   1.014757554   0.906711174       91   0.872927371   0.860852982   1.259332143   1.22904899   1.233920047   1.124972175   0.755960401   0.964278601   1.022142815       92   0.723958825   1.042827462   1.095429219   0.826234772   0.887808103   0.86882034   0.832733403   0.7817925   0.731489497       93   1.029948644   1.117212794   1.515504633   1.312953556   1.580258457   1.031693304   0.790571212   0.786977482   0.845410914       94   1   1   1.00893617   1   1   1   1   1   1       95   0.761058688   1.098734177   1.557008055   1.873970081   1.798895282   0.837204421   1.041066182   1.054288513   0.873233525       96   0.988922062   1.071443537   1.171249738   1.1345066   1.240441022   0.97558229   0.657987256   0.818776093   1.146561195       97   1.075671927   1.16947242   0.955673548   0.938729404   0.976900199   0.938490674   0.929714686   0.869700752   0.793779396       98   0.657545256   0.836369551   0.852520188   0.664682919   0.556048835   0.66883818   0.987078894   1.269471638   1.175280737       99   1   1   1   1   1   1   1   1   1       100   1   1   1   1   1   1   1   1   1       101   2.534574468   1.791914894   2.377021277   2.100106383   1.149893617   1.052234043   1.272978723   1.225638298   1       102   0.970764883   1.113230878   0.912029677   0.914090561   0.991197079   0.979423287   0.679807998   0.790915187   1.106977729       103   1.069533217   1.291206663   1.294499322   1.38194848   1.396281232   0.910310631   0.747921832   0.892445676   0.862986729       104   0.781413253   0.921346577   1.193617679   1.30963019   1.237781826   0.960575787   0.856820588   1.183754585   0.886116354       105   0.716472848   0.73642377   0.943828017   0.901418969   0.943561293   0.790140936   0.703069696   1.014737113   1.046849862       106   1   1   1.027446809   1.280638298   1.169574468   0.813003946   0.930777149   1.104906502   1.328272431       107   0.909853812   0.773681233   1.07515677   1.18255493   1.171334809   0.898503448   1.336004044   0.987781498   1.231655555       108   1.159574468   1.468617021   1.62712766   1.915106383   1.881702128   0.802655909   1.251190676   1.214882053   0.925365608       109   1.297292191   1.072732997   1.064168766   1.608816121   1.174370277   0.993515437   1.057442901   1.514690692   1.583725468       110   0.898518949   1.050248333   1.021253747   0.869479619   1.111190657   0.823364076   0.884497145   0.885404772   0.939247548       111   1.039198581   1.060006909   1.023407905   1.083754398   1.250894337   1.107081501   0.903774665   1.112579953   0.989648546       112   0.899995961   1.61775516   1.656326992   1.455551517   1.54965871   1.09641048   1.111062694   1.841004412   1.611253336       113   1   1   2.027340426   1.915106383   1.764361702   1.320956112   0.947481974   1.244819168   1.116220973       114   0.924956775   0.79126469   0.76771619   0.784204526   0.707557571   1.156379727   1.501436978   1.04664477   1.208156562       115   0.990010852   0.685724152   0.39386839   0.351963299   0.34007498   0.914254643   1.332942948   1.266538012   1.277480341       116   1.279818121   1.08722641   1.051354987   0.788260516   0.73980607   0.881632545   0.662625744   0.547455016   0.674119793       117   1.530531915   1.237765957   1.120425532   1.060957447   1   1.472284264   0.714314721   0.755397631   0.636209814       118   0.492816046   0.687731028   0.71479541   0.661245219   0.387965671   0.737833595   0.793485086   1.083516484   0.906357928       119   0.842094228   1.235295839   1.253459659   1.480646388   1.274383405   0.939248014   1.183941689   1.070729131   0.857807773       120   0.945841357   0.881110206   1.308639461   1.236835284   1.318138054   1.037698821   0.970487636   1.145786218   0.898155244       121   1   1   1   1   1   1.008297872   1   1   1       122   1.304477612   1.477698716   1.634276293   2.137556404   1.692693509   1.247583828   0.979847105   0.97412909   1.206998353       123   1.072574911   0.928593195   0.759827324   0.68166582   0.661249365   1.402035969   1.12129284   0.839616559   0.875992535       124   1   1   1   1   1   1   1   1   1       125   1.123349743   1.131237413   0.646229582   0.583240098   0.847560976   1.278923038   1.018803098   0.877529985   0.993065967       126   1.088523159   1.22423789   1.203977308   2.016582507   1.561373979   0.81847162   1.003719118   1.294474453   1.094173382       127   0.843937156   0.696871223   0.851080972   0.718235531   0.762535249   1.033529098   1.093059263   1.133582488   1.098451682       128   1   1   1   1   1   1   1   1   1       129   1   1   1   1   1   1   1   1   1       130   0.973284082   1.30787733   1.588952839   1.857056954   1.571514475   0.824506697   0.907166956   1.067733361   0.867856047       131   0.757563023   0.705827477   0.864667346   0.775994444   0.872005341   1.41784193   1.674934903   1.860488568   1.950646458       132   0.946389999   0.743617655   0.858715877   0.884503784   0.778287269   0.941115776   1.454321987   1.168853371   1.305275403       133   1   1   1   1   1   1.052234043   1   1   1       134   1.162653798   0.772696104   1.009412237   1.2088999   1.029485206   1.033046715   0.886459762   0.94052476   1.035809682       135   1   1   1   1   1   1   1   1   1       136   1.218245301   1.222310795   0.822521244   0.643878641   0.669435454   1.280797706   1.279263656   0.910891749   0.910958447       137   1.00393617   1   1   1   1   1.027405152   0.773598881   0.773598881   0.773598881       138   1.059360983   0.855003046   0.837698654   1.094080514   1.141259206   1.177029353   0.983552896   0.913019435   0.943844377       139   0.911497132   0.77368317   0.791251895   0.654130134   0.823818314   0.932227635   0.888154334   1.004098044   1.015193691       140   0.90812401   0.891906163   0.72520178   0.826582183   0.749490835   1.652701989   1.28250308   1.033004753   0.920700581       141   1   1   1   1   1   0.981415744   1.101900188   1.609835039   1.092190436       142   1.192433644   0.810324026   0.691140986   0.602924279   0.560611283   1.062429696   1.039192469   1.2064413   1.316026286       143   1.269110502   1.038774234   1.062154231   1.316880743   1.556790302   1.110391092   1.052514489   0.859503491   0.947930452       144   0.856820615   0.904993118   0.604985472   0.612020187   0.6512846   1.069870793   0.838038022   0.906674348   1.115710641       145   1   1   1   1   1   1   1   1   1       146   0.688615426   1.023863752   1.057211816   1.103086651   0.990906619   0.782402006   0.7001837   0.723568255   0.599334707       147   1   1   1   1   1   1   1   1   1       148   1   1   1   1   1   1   1   1   1       149   0.909661463   0.452933344   0.323307982   0.328480705   0.313231415   1.054771242   1.299912854   1.091895425   1.282745098       150   0.679777789   0.826000694   1.048013491   0.958732206   1.179405783   1.062556168   1.303950299   0.943578322   1.023248545       151   1.066702128   1.097021277   1.556276596   1.861489362   1.617021277   1   1.075425532   1   1.027340426       152   0.872956909   1.133079495   1.160568351   1.263837296   1.420690936   1.335797509   1.105423865   1.063640016   0.927842507       153   1.384787234   1.107021277   1.125106383   1.090319149   1.047340426   1   1   1   1       154   1.045472142   0.528660307   0.191220794   0.129959906   0.155219135   1.183728226   1.222116734   0.768100388   1.778915215       155   1   1.006382979 1   1.309787234   1.224148936   0.749362245   0.93614477   0.906967474   0.931999362       156   0.966036465   1.172367345   1.386251022   1.953288113   1.911723673   1.058765984   0.865228545   0.868283139   0.77888138       157   1.359417874   1.133930742   0.839394255   0.820638394   0.706401306   1.221036004   1.049131216   0.693883109   1.20093687       158   0.914359991   0.666666667   0.65010974   0.672292186   0.782522534   0.915537096   0.891617897   0.833641684   0.889748914       159   0.95996732   0.95996732   0.95996732   0.95996732   0.95996732   1.107340426   1   1   1       160   0.812916112   0.78985595   0.745430335   0.668623653   0.648650284   0.982563579   0.859828187   0.918601684   0.799523688       161   1.066906067   0.723222723   0.484461484   0.352323352   0.336123336   0.980411103   1.197909346   0.95686929   0.776748067       162   1.057441462   0.992061909   0.768319438   0.674059596   0.697514859   1.290162643   0.804781984   0.775774987   1.031370187       163   1.049487786   1.07537431   1.100630418   1.300197006   1.03715524   1.021503538   1.228573382   1.011726095   1.168131004       164   1   1   1   1   1   1   1   1   1       165   0.861169898   0.920934564   1.096503852   1.026834843   1.241174977   0.951898734   1.113822785   0.990886076   1.169316456       166   1   1   1   1   1   1.47   1   1   1       167   0.954891801   1.116854617   1.066900335   1.283907345   1.072691253   0.852879479   1.236045933   1.093012694   0.864060033       168   1   1   1   1   1   1   1   1   1       169   1.143297381   1.02312565   1.026832866   0.953669682   0.913226134   1.288242644   1.412503173   1.059860599   0.948222339       170   1.015361976   0.889056387   0.96317433   0.9285381   1.017838556   1.119188805   0.962760911   1.222189279   1.21163425       171   0.949585028   1.052400325   1.004621644   1.112839707   1.352318959   0.943605981   0.909129288   0.953421284   0.963447669       172   1   1   1   1   1   1   1   1   1       173   0.809244733   0.67137018   0.993643495   0.714543323   0.628497581   0.886214012   1.150535521   1.273705414   1.205143952       174   1.038813621   0.694870856   0.47736811   0.60890629   0.447567811   1.070269366   1.282583236   1.365651665   1.199933077       175   1   1   1   1   1   1   1   1   1       176   1   1   1   1   1.008723404   1.077168367   1.043128189   0.969945791   0.903300383       177   1.053421952   0.942392695   0.849043926   0.851982579   0.716610268   1.01657117   0.969544233   0.910875475   0.949707964       178   1.468330951   1.329005382   1.253899717   1.191656278   1.296804208   1.178741935   1.117870968   1.263193548   1.116225806       179   1   1   1   1   1   1.40664693   0.897717505   0.897717505   0.897717505       180   0.835792863   0.647303461   0.765830427   0.717131741   0.630533942   0.924014548   1.337658508   1.146662735   0.963629215       181   0.71089242   0.646826338   0.476049324   0.450794404   0.583313572   0.90112099   1.208581368   1.197448782   1.092307692       182   1   1   1   1   1   1   1   1   1       183   1   1   1   1   1   1   1   1   1       184   1.029001223   0.9223112   1.025052831   1.035285285   1.193471249   1.048929332   1.13165782   0.981222692   1.223413859       185   0.817570476   1.040832795   0.978803529   1.023294599   1.116365397   0.933552767   1.32592745   0.936844271   0.927244051       186   1   1   1   1   1.269042553   0.864769686   0.953162417   1.085998028   0.980067615       187   1   1   1   1   1   1   1   1   1       188   1.063953046   1.079342342   0.675696575   0.47336663   0.381360444   0.790765791   0.834488541   0.861307993   0.923968698       189   1.498051682   0.981469003   0.692048518   0.535875425   0.35295324   0.800642081   0.9049803   0.819508433   0.677750214       190   1   1   1   1   1   1   1   1   1       191   0.926143003   0.746786778   0.695827523   0.574912367   0.509159097   1.052888246   1.005588762   0.73724187   0.895906609       192   1   1   1   1   1   1   1   1   1       193   0.523450911   0.511573177   0.59374827   0.459604629   0.308267346   0.679455358   0.785334373   1.003900433   0.961421176       194   1.310638298   1.167446809   1.387765957   1.137340426   1   1   1   1   1       195   0.832679604   0.77595995   1.188996697   1.235858794   1.248916185   0.963345258   1.160694387   0.838484546   0.551287315       196   1   1.086914894   1.181489362   1.407978723   1.559787234   1   1   1   1       197   0.528817246   0.684321627   0.701081047   0.65460884   0.42560609   0.640370597   0.825328701   0.988350705   0.869882145       198   1.082234043   1.066808511   1.14393617   1.213404255   1.169574468   0.924014548   0.924014548   1.329008159   1.31858842       199   1.042959626   0.913580247   0.926537649   1.246774552   1.285035035   1.092721745   0.868602874   0.747171284   1.038147028       200   1   1   1.134468085   1.24212766   1.299148936   1   1   1   1       201   1   1   1   1   1   1   1   1   1       202   1.005078844   1.213863602   0.539412028   0.527931155   0.4428543   0.718916177   0.897902253   1.935078418   1.534295428       203   0.817386245   0.999720703   1.292330967   1.50315373   1.34556034   0.77223517   0.972264921   0.780763954   0.631063949       204   1.437339986   1.061905075   1.004070111   1.467537583   1.062627191   1.075659696   1.22457024   1.421876711   1.537994087       205   1.028540207   0.966445973   0.847399884   0.721604422   0.604229607   1.048020943   1.212753487   1.346461923   0.87520025       206   1   1   1   1   1   1.052234043   1.233404255   1.118191489   1       207   1.382095907   1.459964147   0.789102181   0.59784882   0.668098297   1.071212427   1.335955887   0.813395199   1.017281958       208   0.624969   0.811765289   0.688309112   0.736223402   0.862358018   1   1   1.225638298   1.120531915       209   1.23092352   1.031132816   0.910874684   0.947850353   1.007499782   0.924014548   1.278875455   1.12543006   0.992430945       210   1.357872713   0.740803815   0.457376411   0.457376411   0.457376411   1.00115556   1.122434381   1.225499367   1.163044076       211   1.032804745   1.153371263   0.990134366   1.016704999   1.171952548   1.191763611   0.741461145   0.837040484   0.816333178       212   1.029394351   0.918782433   1.430258071   1.043603942   1.460453453   1.149957647   1.158810831   1.383255458   1.264748477       213   1.158582709   1.270851304   1.339592595   1.049167275   1.359763785   0.869298648   0.848240889   0.719946138   0.802830621       214   0.885686893   0.662813251   0.702280458   0.696579313   0.623706038   0.826568059   1.368826512   1.180771493   1.370717427       215   1.023648373   0.928687923   1.567724048   1.611188127   1.745576123   1.301578444   1.468989158   1.245934311   1.33075574       216   1.353798614   1.428116612   1.141862788   0.985985392   0.991416443   1.150247058   0.874942693   0.900208853   0.99689267       217   1.061753594   0.907326182   1.102734471   1.222449009   1.218859021   0.919472477   0.979107986   0.597810069   0.70122554       218   0.855538585   0.679392549   0.689825126   0.648380781   0.640323373   0.939326565   1.730682104   1.483066253   1.764857231       219   1.006141557   0.869562678   0.98287822   1.128420088   1.118149716   1.309995132   1.510283141   0.997140191   1.036082265       220   1.180192117   1.356409407   1.03516617   1.18758971   1.732527327   1.369763165   0.838092917   0.613000421   0.9531205       221   1.308049259   2.121274317   1.003034089   0.838836338   0.89889345   1   1   1   1       222   0.870579067   0.663469608   0.563481597   0.563481597   0.563481597   1   1.185957447   1.25957447   1.04287234       223   0.840122544   1.192976784   0.63222797   0.404874069   0.564551389   0.800168934   0.772117009   0.734995999   0.805059127       224   1   1.307978723   1.845106383   1.797659574 1.309148936   1   1   1   1       225   2.239912281   0.681641604   1.105451128   1.341353383   0.588972431   1   1   1.017659574   1.213085106       226   1.033286761   0.862862112   0.566213083   0.582815589   0.462763269   0.540268147   0.212409869   0.750362828   0.784963948       227   1.100829611   0.828028079   0.748283344   0.704275686   0.520485003   0.993322596   1.102073686   1.082679015   1.423360848       228   1.163294798   1.124587118   1.481 523534   1.557648637   1.502477291   0.942812803   1.166207565   0.955887488   1.048806984       229   1   1   1   1   1   1   1   1   1       230   1.078369646   1.222019717   1.383646757   1.293761909   1.283655041   0.883856068   0.775236534   0.847575058   0.945988229       231   0.909078328   0.986051527   1.07844935   1.143301965   1.120496586   0.793122044   1.208422909   1.245173844   0.706805081       232   0.780819127   0.722633521   0.753152664   0.641739682   0.759763635   0.7363115   0.633987323   0.668035014   0.637971627       233   1   1.448510638   1.310212766   1.407978723   1.410531915   0.971375426   1.20584892   1.227756536   1.496951535       234   1.052363039   1.321874865   1.34669434   1.253599689   1.815583517   1.151781583   1.071263304   0.840898574   1.015985865       235   1.068432876   1.04115998   0.813322689   0.846573715   0.783636262   1.042087502   0.837145956   0.904013499   1.252139327       236   1.037959585   0.862685939   0.905697446   0.968074656   0.94716531   0.962774869   0.830314136   0.916439791   0.818167539       237   0.912105954   1.128064799   1.217053415   1.281414186   1.338879159   1.029201937   1.158429749   0.952241896   0.903116105       238   0.897803152   0.860543536   0.491553152   0.426382212   0.402978098   1.152399086   0.996572734   0.964737243   1.114166032       239   0.984156363   1.410824017   1.681868661   2.018731028   1.678759162   1.005047374   1.184229169   1.115691136   1.153280793       240   1.09787234   1.076914894   1.632234043   1.568829787   1.329361702   1   1   1   1       241   1   1   1   1   1   1   1   1   1       242   1.085456528   0.808631572   0.443243779   0.385843164   0.335910908   1   1   1   1       243   0.474956212   0.244652986   0.15105012   0.15105012   0.15105012   0.985961885   0.752293938   0.859736491   0.790212532       244   0.749535508   0.766205615   0.811725846   0.816061107   0.557855078   0.833762193   0.701773283   0.91372948   0.865657351       245   0.931560462   1.593677873   0.875388861   0.751756147   0.822779729   1.170018282   1.144777968   1.594090936   1.870672878       246   1.00393617   1   1   1   1.219148936   1   1   1.009893617   1       247   1.09375593   1.13125   1.04147889   1.074881404   1.348031309   1.08893192   0.944019605   1.237459932   1.159473563       248   1   1   1   1   1   1   1   1   1       249   1.154396891   0.877249015   1.097546045   0.910039391   1.034334079   1.022269591   1.018539294   1.081365345   0.994951478       250   1.327738319   1.323613721   0.842500876   0.76758926   0.848186132   1.410320822   1.130753128   1.118124726   1.481933694       251   0.983422447   0.677935987   0.658416455   0.705227797   0.650053303   0.962922931   1.671628836   1.18173332   1.488732763       252   0.93067653   0.976375134   0.973034244   0.931690729   1.100465338   1.175323686   1.116222391   0.866488957   1.211805027       253   0.893510825   0.90358757   0.990079795   0.680674967   0.77977667   0.98782554   0.928453796   0.892709361   0.943366422       254   1.007696887   1.260588535   1.106225549   0.97763225   1.585005953   1.047746076   0.967022346   0.847637826   1.028802289       255   0.95629276   0.952256731   1.240192942   1.432298076   1.103214057   1.010490694   0.845211506   0.78463621   0.73258832       256   0.940914436   0.772238056   0.836027345   0.884220597   0.773962091   0.917123921   0.680502466   0.643071825   0.688840937       257   0.717037778   0.718330414   0.820323576   0.780335251   1.05545826   0.915473068   0.889919978   1.158429157   1.473135633       258   0.827142324   1.223205852   0.482600004   0.365173648   0.277121455   0.626066413   0.631771449   1.463429146   1.363302271       259   1.450548454   1.037621249   1.270691687   1.310851237   1.094189103   0.995043325   1.056689675   1.305845205   1.172602438       260   0.68085961   0.822454308   0.430541608   0.381803575   0.566847426   0.727926837   1.346109878   1.41846547   1.374016542       261   1.082234043   1.318085106   1.14393617   1.339042553   1.264042553   1.254870024   1.299302886   0.89009056   0.980975959       262   1.274563782   1.018547098   1.261133125   1.134223149   1.103524505   1.157578383   0.926551828   1.112371306   1.081811215       263   0.909432403   0.848164983   0.936290898   0.979827955   0.952819203   0.943419724   0.872366207   0.719320094   0.749175362       264   1.037586117   0.923955699   0.880265109   0.863172582   0.987180605   1   1   1   1       265   1   1   1   1   1   0.991665788   0.991665788   0.991665788   0.991665788   0.991665788   0.991665788       266   1   1   1   1   1   1.052234043   1   1   1       267   1.097622028   0.784313725   0.784313725   0.784313725   0.784313725   1.647169473   1.847456109   0.841992118   0.871551415       268   0.772090308   0.59366485   0.603688206   0.712874659   0.53946088   1.132725528   0.733829175   0.883661228   0.807653551       269   1.056918029   0.864447781   0.522800578   0.383633634   0.348793238   1   1   1   1       270   1   1   1   1   1   1   1   1   1       271   0.927421184   1.250829914   1.284830615   1.318522031   1.037526547   0.904151499   1.076046265   1.148994398   0.779787262       272   1.450062628   1.186927286   0.796591733   0.501977718   0.382358758   1   1   1   1       273   0.887386355   1.184964474   1.164871266   0.940637176   1.565665826   1   1.027978723   1   1.159148936       274   1.066702128   1   1   1   1   1   1   1.009893617   1       275   0.736158355   1.102046521   0.518562318   0.511823721   0.350187709   0.539720226   0.8203125   1.899023036   1.805553773       276   0.893111978   1.055275426   1.183093902   1.038340786   1.282656265   0.791386594   0.914662983   0.822577646   0.869497064       277   1.195298557   1.136250064   1.120442609   1.199326908   1.394013564   1.00199636   1.001878927   0.900504962   0.849715225       278   0.744456918   0.796449621   0.934675835   0.928641594   0.87349144   0.977403055   0.806563334   0.88735593   0.733151649       279   0.951944381   0.780579112   1.546413019   1.886469555   2.055924822   0.951061399   0.778633864   0.737001514   0.710752145       280   0.891596639   1.191848739   1.309495798   1.495798319   1.92302521   1.023048011   0.912062974   0.93872775   1.113254379       281   1.020361132   1.788011062   1.234247912   1.277437371   1.208355927   1.241904353   1.069568947   2.032897276   2.051168775       282   1.096576873   0.878720151   0.905246442   0.856134572   0.99011881   1.003133789   1.371313781   1.545198875   1.540136601       283   0.91711175   0.936010682   0.905901514   0.777181888   1.111940956   0.848944297   1.274967896   0.838378995   0.829428526       284   1.27883885   0.939880629   1.500759831   2.126424308   2.540314704   1.060498021   0.769522272   0.597972935   0.630318523       285   0.752120339   0.752120339   0.752120339   0.752120339   0.752120339   1   1   1   1       286   1.064377811   0.904317841   0.694002999   0.648215892   0.716131934   0.898512686   0.858899582   1.092592593   1.098911247       287   1.098424169   1.135208079   0.672079053   0.512188752   0.614966046   0.974699685   0.788604792   1.148882625   1.112609892       288   0.916783165   0.69163417   0.89163417   0.69163417   0.69163417   1   1   1   1       289   1   1   1   1   1   1   1   1   1       290   1   1.066808511   1   1   1.066808511   1.065302247   1.482962338   1.780778653   1.437809896       291   1.074103272   0.926290895   0.926290895   0.926290895   0.926290895   1.070428475   0.792847503   0.792847503   0.802041161       292   1.195830005   1.091287568   1.756911548   1.484702891   1.715976731   1.019646441   0.853040293   1.058034719   0.982876254       293   0.822771403   0.722241836   1.126345984   1.85423654   2.012842012   0.991082134   1.120690947   1.039418465   0.883917866       294   0.85695247   1.22848385   1.174432884   1.355557883   1.445763406   0.870942884   1.052566039   1.003735783   0.933594304       295   1   1   1   1   1   1   1   1   1       296   1   1   1   1   1   1.36455676   0.749362245   0.749362245   0.749362245       297   1   1   1   1   1   1   1   1   1       298   1.211243612   0.8459682   0.929230551   0.899985804   0.82673197   1.130572065   1.00083581   0.955980684   0.944372214       299   0.897078384   0.633169747   0.64289318   0.779617484   0.925744164   1   1   1   1       300   1.164877471   0.695935441   0.695935441   0.695935441   0.695935441   1   1   1   1       301   0.751753106   1.025949525   0.479122913   1.514968142   0.658420247   1.413864344   1.681170936   1.516655012   1.229928167       302   1   1   1   1   1   1   1   1   1       303   0.922592958   0.752951786   0.941509553   0.931275297   0.872512216   1.005249908   1.024560973   1.220864546   1.240359818       304   1   1   1   1   1   1   1   1   1       305   0.834813642   0.620654811   0.670333019   0.757182669   0.68153658   1.074743563   1.8983562   1.406631048   1.683992032       306   1.062001532   1.156851259   0.752579642   0.664488803   0.529040689   0.958388713   1.315100705   1.008553999   0.756159902       307   0.804019765   0.743956998   0.910590278   0.718215812   0.744825053   0.825699074   0.778742386   0.912417862   0.814283659       308   0.889202541   0.794424841   0.663373324   0.663373324   0.805434016   1.285494803   1.000813376   0.849525531   0.849525531       309   0.916009251   1.140251151   0.78580846   0.678085893   0.618734735   0.894159197   1.13729128   1.160851197   0.951561347       310   0.945361505   1.110817652   1.025118301   1.233602949   1.674947728   1.593465288   0.937869895   0.590813094   0.984767605       311   0.846784554   0.92080405   0.947933197   0.908788634   1.189904028   1   1   1   1       312   1   1.157340426   1.167446809   1   1.269042553   1   1   1   1       313   0.893744644   0.732258316   0.732258316   0.732258316   0.732258316   1   1   1   1       314   1   1   1   1   1   1   1   1   1       315   0.725557726   0.573815154   0.828364347   0.843117097   0.901408451   0.938459105   0.752649897   1.602990033   1.599588673       316   0.704719559   0.608078427   0.611614078   0.659559651   0.586489527   0.871253189   0.811782526   1.947464923   1.662547832       317   0.547753627   0.547753627   0.547753627   0.547753627   0.547753627   0.821625372   0.464141394   0.514143434   0.632066615       318   0.98698026   0.98698026   0.98698026   0.98698026   0.98698026   1   1   1   1       319   0.842217184   0.72088364   0.918718476   1.052898895   1.386724311   0.801346986   2.147474858   1.213437004   0.811440253       320   0.795805269   0.725196806   0.58112371   0.442720323   0.489243186   0.931445375   1.010020487   0.704388667   0.54754505       321   1.260029718   1.185642645   0.872956909   0.872956909   0.872956909   1   1   1   1       322   1   1   1   1   1   1.259777645   0.933095096   0.933095096   0.933095096       323   1   1   1   1   1   0.990589198   0.961538462   0.961538462   0.961538462       324   0.860478947   0.74707163   0.987596241   0.849944247   1.196378697   0.79318267   0.884489897   0.895059709   0.682514738       325   0.695810831   0.809243176   0.423277624   0.350788206   0.347704715   0.753281088   0.57437919   0.651449344   0.611533377       326   1.111037863   0.843761644   1.208117172   0.803147124   0.745306544   0.700875458   0.72222288   0.94451684   0.705963536       327   1   1.237765957   1.267021277   1.251702128   1.528617021   0.924825477   0.561818497   0.542318122   0.542318122       328   0.753382865   0.88546714   0.777287247   0.734611105   1.259323068   1.011495164   1.233272554   0.86629935   0.846123355       329   0.845399766   0.850795935   0.845399766   0.845399766   0.845399766   1   1   1   1       330   0.807253202   0.875614715   1.101360627   0.987245208   1.239821363   0.98258426   0.839732231   0.991945444   0.931178292       331   1   1   1   1   1   1   1   1   1       332   0.95894405   1.071355398   0.633018125   0.596217494   0.51678487   0.92859352   1.474251914   1.525632104   1.015193691       333   1   1   1   1   1   1.151595745   1   1   1       334   1   1.147340426   1.200425532   1.915106383   1.349574468   1   1   1.195   1.066276596       335   1.144148936   1.016489362   1   1   11.053385883   0.841992118   0.841992118   0.841992118       336   0.738508576   0.725190444   0.577861844   0.657045137   0.79022646   1.153766545   0.933656517   0.942099243   1.453292663       337   0.994606244   1.223287512   1.130370457   1.100675676   1.101432898   0.906604403   1.021347565   1.093087699   1.201390671       338   1.407893579   1.511469303   1.246296677   1.131332316   1.510948637   1.344494932   1.005867873   1.0126998   1.154036493       339   0.881003174   1.216140278   1.126801603   1.604193767   0.972995473   0.777144325   1.039856189   1.49424756   1.006111967       340   0.796981774   0.955322072   0.803578539   0.739228691   0.611884939   0.840370584   1.049907548   0.982337212   0.754849585       341   1.105339757   0.98067851   1.196627522   1.25529459   1.161648098   0.969927956   1.024861701   0.830792487   0.908079249       342   1.028626129   0.864802843   0.739283232   0.687276256   1.202402339   1.212553588   0.934395766   0.704579908   0.836261091       343   1   1   1.139255319   1.378404255   1.264042553   1.104368634   0.576757884   0.636028961   0.673027365       344   0.844010727   0.922973778   1.047675805   1.266239571   1.276445173   0.857194966   1.145540762   1.096480029   0.933977749       345   1.210310049   0.749700175   0.931069736   0.789729273   0.650138608   1.307980883   1.396076366   1.347191531   1.169073436       346   0.996290408   0.996290408   0.996290408   0.996290408   0.996290408   1   1   1   1       347   0.902544407   0.902544407   0.902544407   0.902544407   0.902544407   0.855700245   0.717733496   0.922914262   0.892630193       348   1.007508005   1.284807331   1.227669206   1.251628575   1.476758308   1.050151238   1.046603682   1.041188991   1.062287613       349   0.933836019   1.005468782   1.093632183   0.974437585   1.194928947   0.99657444   0.853637828   0.877001903   0.962377397       350   0.725987211   0.950029666   0.880908432   0.863306744   1.174500626   1.046633711   1.390699506   1.022879391   1.07187541       351   0.823974788   0.784138514   0.573965179   0.37737807   0.358372728   1.013015991   1.444987515   1.391010997   1.1788397174       352   1   1   1   1   1   1   1   1   1       353   1   1   1   1   1   1   1   1   1       354   0.837285432   0.856885046   0.57266966   0.441264112   0.57061317   1.044607654   1.063548512   0.984847313   0.864785466       355   0.858909796   1.107081902   0.782738785   0.869276639   0.661265513   0.924901634   1.173463983   1.072204146   0.884269068       356   1   1   1   1   1   1   1   1   1       357   1.209906618   1.425091352   1.420567252   1.618989618   1.321269068   0.819803643   0.800776159   0.723681543   0.679139274       358   1.372111276   1.527339322   2.244789396   2.209296241   2.656492544   1.486865851   1.680770002   1.341387608   1.04882695       359   1.1441 48936   1.227659574   1.219361702   1.146808511   1.43606383   1.459336571   1.460369949   1.078743412   1.058385863       360   1.260572544   1.079279728   1.208523097   1.130123617   1.139289678   0.976833525   0.944053353   0.856516059   1.056005148       361   0.914475635   0.960734407   1.959251754   2.446130276   3.190718592   0.955225873   0.888655823   0.876527908   0.944375584       362   1   1   1   1   1   1.115842764   1.04030176   1.214909668   1.060055589       363   1   1   1   1   1   1   1   1   1       364   1.29470332   1.043779055   1.052783777   1.013836524   1.067608624   1.092970791   1.215625742   1.018522916   1.133341249       365   1   1   1   1   1   1   1   1   1       366   1.455028644   1.493984723   1.907893062   2.259707193   2.132972629   1.227277286   1.252197894   1.144041451   1.218017717       367   1.123284092   1.093721692   2.001515574   1.774719532   1.847083827   1.072928038   1.078022461   1.104736809   1.287508627       368   1   1   1   1   1   1   1   1   1       369   0.946656217   0.855067921   0.992998955   0.977742947   1.006321839   1.08752992   1.046228939   1.192518891   1.09729197       370   0.918603277   1.081508961   0.869176876   0.786752283   0.844342576   0.835062886   0.986209094   0.910495653   0.860968246       371   1   1   1   1   1   1   1.122765957   1   1.035106383       372   0.604395604   0.832444255   0.943828017   0.594100075   0.730395818   0.971375426   1.052288933   1.123592022   0.971375426       373   1   1.458617021   1.729893617   2.166276596   1.622234043   0.868360277   0.88594204   0.922446547   0.79557476       374   1.198828842   1.633765645   1.134291429   1.040640013   0.929153178   1.227704371   1.080964135   1.000726006   1.366429505       375   0.80751082   1.649109961   0.706287221   0.98174363   0.75018712   0.950673593   0.877401917   1.168503737   1.324549179       376   1   1.026595745   1.101808511   1.071595745   1.299148936   1   1   1   1       377   0.987031033   1.059918312   0.774601036   0.787991073   0.625584235   1.081811942   1.0061312   0.848318463   0.776801647       378   1   1   1   1   1   1   1   1   1       379   1.757057732   1.524372375   1.607599883   2.194099834   1.796913158   1.044602359   1.181811309   1.022074388   1.1005443       380   1.085181027   1.141664328   1.530592198   1.747544204   1.749929834   0.876528202   0.724228952   0.951132259   0.875382051       381   1.077035455   2.262628533   2.349159971   1.423498342   3.175591392   1.138477157   1.093739425   0.696717428   1.340169205       382   0.696719182   0.592457328   0.864962332   0.733225348   0.445683898   0.692066806   0.578249439   0.879803603   0.822546973       383   1   1   1   1   1   1   1   1   1       384   1   1   1   1   1   1   1   1   1       385   1.329587063   1.207282343   1.167743084   1.277817331   1.179287022   0.947535936   0.971063635   1.130265649   0.998044559       386   0.713741987   1.383847489   1.496961806   1.580328526   1.124031784   0.970026047   0.996273292   1.206050892   0.82163895       387   1.0696199   0.940630567   0.646307385   0.609649518   0.50391 6897   0.964072134   0.957726463   1.017279482   0.880093503       388   1.057379261   1.258566418   1.13625326   1.107293821   0.922475043   1.109041969   0.759448473   0.876235992   1.105581191       389   0.9527833   1.466302187   1.472962227   1.699502982   2.160636183   0.684930614   0.867092319   1.131409212   0.878624015       390   1.050503077   1.107648725   1.964051968   1.951304093   1.820504054   1.043136815   1.088685701   1.066584394   1.410865541       391   1   1   1   1   1   1   1   1   1       392   0.972771971   1.009784009   0.89233875   0.772218369   0.689871693   1.107698795   1.115169403   0.833816162   0.883223374       393   0.945964957   0.828494692   0.999552372   0.888284947   1.202327663   0.788267288   1.310929811   1.066045066   03873219373       394   0.912976399   0.646735051   0.607997665   0.563547661   0.646109582   1.044526627   1.178550296   0.884023669   0.827366864       395   1   1.197553191   1.069148936   1.203829787   1.219148936   1   1   1   1       396   2.3688923   1.674597084   2.028651829   1.500724823   1.34228703   1       397   0.779081559   0.771886619   0.636583128   0.516248974   0.594234391   0.869260978   0.806640486   0.858550518   1.064976794       398   1.233835317   0.965735459   0.76583451   0.714877928   0.549846837   1.068628613   1.055159003   1.114515402   0.989921506       399   0.749524107   1.038099838   1.050629315   1.128903032   0.976674148   0.740349876   1.031343094   1.245832541   0.988478798       400   1.00393617   1   1   1   1   0.95106214   0.933095096   0.942326782   0.933095096       401   1   1   1   1   1   0.915109034   1.099785826   1.135611371   1.088979751       402   1   1   1   1   1   1   1   1   1       403   1.069885467   1.267197037   1.32096564   1.346821206   2.635141623   1   1   1   1       404   1.265744681   1.318085106   1.276595745   1.137340426   1.400319149   0.91260732   1.162313601   1.164121103   1.199367375       405   0.93105365   0.89535554   0.667579363   0.797854819   0.87573599   0.80516226   1.367121915   1.319978699   1.481142714       406   1.059814742   1.444225463   1.63618447   1.684765471   1.663874655   0.698933441   1.009990549   0.939966698   0.716034382       407   1   1   1   1   1   1.134733158   1.102686789   1.202158064   0.940507437       408   1   1.65   1.422021277   1.630425532   1.590957447   1   1   1   1       409   1.064658712   0.940849521   0.601602803   0.609297357   0.493831628   1.044193225   0.886810354   1.012792994   0.936267378       410   1   1   1   1   1   1   1   1   1       411   1   1.700531915   1.62712766   1.203829787   1.244042553   0.75011262   0.731771671   0.856425767   0.913894073       412   1   1   1   1   1   0.915473068   0.884876605   1.069665792   1.07477641       413   0.908472699   1.063661535   1.630302359   1.807043969   1.816303024   0.925202382   1.018097277   0.8358868   0.864253696       414   1.034842773   1.156067448   1.021419398   0.754236235   0.77263123   0.894804872   0.90857569   0.873626647   0.783942332       415   0.988227503   1.029651976   1.014200574   0.987565301   1.025163711   0.946519482   1.192247593   1.241897273   1.097232723       416   1.412992323   1.151487096   1.450487984   1.26459129   1.143849092   1.063879148   0.86366334   0.987510116   0.96870785       417   1.369501466   1.479301644   1.4231057761   1.502966651   1.729864284   1.012023414   1.040895428   1.058297738   1.162790698       418   0.924456655   0.913846635   0.973419107   1.008867743   1.115437021   1.084594445   0.802897481   0.99531697   1.081941497       419   1.395025189   1.39697733   1.161649874   1.127267003   1.570528967   1.252402789   1.20993781   1.042967523   1.106476537                   L   M   N   O   P   Q   R   S   T       1   CA3.JRFnCMS   DG.CMS   DG.IMP   DG.IMPnCMS   DG.JRF   DG.JRFnCMS   DR.CMS   DR.IMP   DR.IMPnCMS               2   1   1   1   1   1   1   1.103871183   0.617720674   1.7585750042       3   1.101702128   1   1   1   1   1   1.038510638   1   1.33893617       4   1.257255809   0.740795287   0.490586315   1.034191776   0.374159137   0.422282371   1   1.751382979   1.157340426       5   1.018895145   1.124839329   1.056286399   0.595109256   0.434105083   0.722662139   1   1   1.275319149       6   1.076125307   0.947703704   0.913407407   0.791679012   0.499975309   0.848493827   1.030540614   0.979168566   1.287218525       7   1   1   1   1   1   1   1.795   1   1.747234043       8   0.780506873   1.005395324   1.02511157   1.157130487   2.296542996   1.414707254   0.850643131   0.643130816   1.264709907       9   1.028533628   1.245547349   1.435157589   0.750773905   1.005658503   1.609455315   1.310610406   0.983449406   1.728029496       10   1.296049205   0.909671324   1.098173385   1.005611544   0.395613834   0.859883188   0.93899243   1.356720584   1.052475042       11   1.209910227   1.102421181   1.073419265   0.868663996   1.356906462   1.175492075   1   1   1.444042553       12   1.033041788   0.977387705   1.114211252   1.104783075   1.908860954   1.592595432   0.952665424   0.940070774   1.245576652       13   0.762561346   0.930115128   0.904009291   1.099222379   2.517521713   1.876792567   0.855400855   0.855400855   1.154336154       14   1.734574468   1   1.118617021   1   1.101382979   1.290638298   1   1   1       15   1   1   1   1   1   1   0.908032299   1.063790905   1.335826604       16   1   1.117156016   1.224620994   1.366628286   1.864901171   1.888025331   1   1   1       17   0.848712525   1.313788228   1.65324801   1.495051715   0.699456805   1.055435672   1   1   1       18   0.79125751   1.102656637   0.99721727   1.191921388   1.466324623   1.098612983   1.492798403   1.44241099   1.883681133       19   0.9074754   0.994816529   0.892904208   1.484229947   2.387178962   1.270682637   1.120951499   1.007371898   1.140327908       20   1   1   1   1   1   1   1   1   1       21   1.009797653   0.900424854   0.836453355   0.65582404   0.687975748   0.960125686   1.037447823   1.260405486   1.661359571       22   0.782862085   1.014555168   0.898386393   0.59043829   0.664467946   0.867913214   1   1   1       23   0.648857596   0.953076976   0.71825695   0.498019261   0.394132914   0.859640735   1.326096913   1.654850234   1.37849226       24   0.962024365   1.059982914   1.002867952   1.034720527   1.669270198   1.217415182   0.914840368   0.679586039   1.028239989       25   1.064983792   1.03853491   1.10754483   0.700925219   0.448302175   0.908098054   1.023243802   1.596177686   2.061363636       26   0.839760069   1   1.064468085   1.343191489   1.043723404   1.101808511   1.017888428   0.907791609   0.866758875       27   0.974536237   0.981601926   0.984871896   1.182687125   0.736030759   0.962485177   0.809792361   1.265316585   1.168332906       28   1   0.92055089   0.932014489   0.551247861   1.781395534   1.306452255   1   1   1       29   0.796315594   0.983527178   1.00517446   1.193543793   2.059340138   1.289627344   1.125736016   0.947767419   0.916192345       30   1   1   1.041914894   1   1.262234043   1.164468085   1   1   1       31   0.993247607   0.979115939   0.991477805   0.943669226   0.877692452   0.895813823   0.934879271   0.989362301   0.509070749       32   0.834916304   1.101290442   0.799147938   0.52713633   0.650469252   0.750864411   1   1   1.036382979       33   1.314308322   0.978795776   0.634663741   0.346984867   0.267160426   0.228436886   0.924531516   1.539449988   0.599075201       34   0.997838398   1.0127772   0.841037547   2.02838844   2.520246578   1.609735009   1.045008578   0.669884546   1.187601428       35   0.750170364   1.029442818   0.910687719   0.320223641   0.580097903   0.617651293   1.180385257   1.293498796   1.52604186       36   1.797649333   1.005809468   1.443017292   1.327327191   1.616121273   1.97816911   1.115050505   1.098080808   1.15       37   1.248002333   0.865833034   0.676574591   0.555065854   0.730589863   0.687285399   1.110205584   1.056522425   0.619801251       38   0.933202549   0.994965969   1.02648747   0.358184612   0.381018097   0.669761315   1.313651465   1.715795832   1.195560254       39   1   1   1   1   1   1   1   1   1.370531915       40   1.161808511   1   1.050957447   1.679574468   1.331170213   1.155531915   0.990388874   1.193506954   1.026175923       41   1.154255319   1   1   1   1   1   0.84125852   0.929069583   1.270486606       42   1.130372324   1.088880213   1.216637387   0.761663088   0.503253302   0.952176459   1.140636669   0.991971621   1.410380881       43   0.964555269   1.087534527   1.094983516   1.139623986   2.057881137   1.287570168   0.851992262   0.622359447   1.026224767       44   1.088105207   1.001698754   1.140713477   1.284470555   1.102774632   1.176741223   0.917400475   0.898717648   1.399872769       45   1   1   1   1   1   1   1   1   1       46   0.640959028   0.883288006   0.805451901   1.080661143   1.038032593   0.978664643   0.904647275   0.866599799   1.907255099       47   1   1.141220994   0.936161737   0.936161737   0.936161737   1.132158152   1   1   1       48   1.221914894   0.524964809   0.308334023   0.235385443   0.194584748   0.194584748   0.908479747   1.426247105   0.531043444       49   1   1   1   2.93712766   1.147340426   1.110744681   0.904063366   1.29082812   0.919411913       50   1.26855394   0.961353586   1.132666795   0.795103506   0.602448247   0.815740563   0.9290144241   1.304266607   0.735784204       51   0.921338319   0.949799826   0.827554395   0.384386423   0.414482158   0.579704091   1.335097181   1.533123028   1.127709372       52   0.862805137   1   1   1   1   1.048297872   1   1   1       53   1.873187465   0.83237586   1.050848805   1.829573013   2.421699201   1.748479307   0.965321312   0.839864447   1.059010902       54   0.889018521   1.385040716   1.452297175   1.558158239   1.861264703   1.60058309   1   1.141170213   1.058723404       55   0.902404907   1.017979241   1.110946712   0.822068285   0.992108862   1.093415832   0.93772513   1.116395764   1.230515582       56   1.266914894   11.118617021   1.238510638   1.400425532   1.173404255   1   1   1.243297872       57   1.018685111   1.06132114   0.905813669   1.641504042   2.376071691   1.701804524   0.900267514   0.8663894   1.580902023       58   0.957543427   1.540170671   1.614326517   0.984439889   1.407366521   1.487480068   1.225028681   1.010436327   1.339310166       59   1   1   1   1   1.043723404   1   1.012591815   0.896689879   2.08976438       60   0.91881406   1.055205521   1.353285329   0.726372637   0.669166917   1.401390139   0.849832746   1.385317783   1.001898563       61   1.338031102   1.46948589   1.50828456   0.520182453   0.449564477   0.970791086   1.008471074   1.108161157   1.186570248       62   1   1   1   1   1   1   1   1   1       63   0.831556503   0.810053109   0.741246416   1.605278   1.305329699   1.113878836   0.989600682   1.066526785   1.047223133       64   1.442209274   0.953370052   1.090596014   0.651979313   0.312010272   0.780301667   1.280011857   1.190470309   0.865724731       65   1.145988208   0.796242658   1.063641807   0.667988155   0.253919966   0.595171443   1.04457325   1.459991306   0.902825677       66   0.802644673   1.168877343   0.996664722   1.553138794   1.990445474   1.261967924   0.93901366   0.788840985   0.742966499       67   1.171043835   1   1.141382979   1   1.020638298   1.137553191   1.219148936   1.276808511   1.548723404       68   0.764546936   0.931890895   0.89618242   0.803589827   0.735019793   0.929098205   0.953429402   0.907848352   0.955037417       69   1   1   1.145851064   1   1   1   1   1   1       70   0.927125506   1.095564339   1.021607378   1.443039087   2.049187527   1.514624506   1   1   1.674042553       71   1.073745023   1.221236586   1.231336589   0.873384498   1.290375096   1.206917173   0.950592054   1.004508024   1.410049889       72   0.941984284   0.859453156   0.641083868   0.399300334   1.189032436   1.200079786   1   1   1       73   0.848806973   0.951680841   0.791216162   0.837388995   1.019343761   0.852171813   1.395205184   1.336846652   1.1613131749       74   1   1   1   1   1   1   1   1   1       75   1.085030066   0.965185044   1.135062953   0.739173979   1.066959176   1.017312095   1.051844185   4.468234851   1.831482875       76   1.180184591   1.002048664   1.402644639   1.103616385   1.604169634   1.821919609   1.183887745   1.184349679   1.257509144       77   1.070558456   0.94876881   1.086730506   0.954924761   2.03255814   1.478043776   1.139059305   1.215713438   1.592123491       78   1   1   1   1   1   1   0.781681497   1.28198834   1.365296103       79   1.465534549   0.976688404   1.352372366   1.012892587   1.209654449   1.285960573   0.950485195   0.853363192   1.541262337       80   0.852931911   1.047319226   1.093470077   1.284239907   2.799558614   1.61547449   0.813207208   0.646440759   0.742621086       81   1.026797538   1.081992557   0.778700258   0.592499284   0.704093902   0.59782422   1   1   1       82   1   1   1   1   2.456382979   1.948723404   1   1   1       83   1.108391862   1.079455253   1.096420233   0.876420233   1.352140078   0.891284047   0.87255175   0.87255175   1.469785575       84   1.00769756   0.930976927   0.950967108   0.755169367   0.839567992   0.909631811   1.219954091   1.328988359   2.135923922       85   1   0.561973169   0.722980727   0.591653805   0.769183585   0.992322609   1   1   1       86   0.764236961   1.015604102   1.064199733   1.236736514   1.892618305   1.253232278   0.716803654   0.666352692   0.943523309       87   0.824757644   1.211308684   1.280035751   1.737087214   2.543371907   1.990638818   0.875189448   0.749969279   1.008315242       88   1.198447502   0.964168451   1.139700214   0.617958601   0.980785153   1.272319772   1.249825565   1.66225928   1.417387664       89   1   1   1   1   1   1   1   1   1       90   0.822997189   1.03375267   1.187230002   1.111417042   1.75005934   1.070021362   1.016506816   1.316930871   1.49975809       91   0.935820983   1.052880688   0.96819119   1.533202796   2.236809004   1.727115941   0.899897843   0.871281954   1.127743989       92   0.860299813   0.913536716   1.1244826   1.117813889   2.230032194   1.86432623   1.072339382   0.700735655   1.069641981       93   1.022850861   1.024844226   1.149312362   1.571990885   2.081177989   1.776848178   0.986691982   0.818235606   1.6886241611       94   1   1   1   1.898723404   1.112872341   1   1.044723142   1.054365831   1.029637956       95   0.872673849   1   1.046382979   1.232659574   1.043723404   1   0.859719597   0.830917874   1.128701953       96   1.018072951   0.777135802   0.898419753   1.523580247   1.971308642   1.573530864   1.107228693   1.335287748   2.086760162       97   0.775925321   1.106164576   1.0579377   0.947741837   0.667436921   0.765966545   1.000090831   0.888072907   0.533469467       98   0.806399367   1.148100616   0.831215777   0.889609001   0.338017625   0.840648528   0.900495219   0.951072974   0.714810464       99   1   1   1   1   1   1   1   1.015531915   1.047553191       100   1   1   1   1   1   1   1   1   1       101   1.139255319   1   1   1   1   1   1   1   1       102   1.162496029   0.915716989   1.050295977   0.799178512   1.449120122   1.2171707   1.485274239   1.095154221   2.136238889       103   0.88384133   0.94960855   1.029638375   1.221759662   2.196905679   1.308189387   1.133491144   1.012089445   1.265333728       104   1.050580851   1.182500839   0.827581385   1.808633516   2.246112541   1.465558228   1.050341742   0.726357334   1.150327595       105   0.930240041   1.133824965   1.015996096   1.126287821   1.219607418   0.915844269   1.201292961   1.267985413   1.450160239       106   1.039715217   1.100472813   1.04964539   1.098108747   1.714766321   1.026004728   1   1   1.465       107   1.163457044   1.22817437   1.481764753   1.395471689   1.184049346   1.111554254   1.072264963   1.23325075   1.44547529       108   1.041855774   1.019343422   0.939101782   1.203563583   2.004271418   1.312911887   0.728415844   0.73236922   0.980462672       109   1.49334328   1.312081208   1.238423842   0.470047005   0.501450145   0.649264926   1   1   1       110   0.877587469   1.273558613   1.285490333   2.52421181   1.743250305   1.295593102   1.202892674   1.275209516   1.178201316       111   0.989168098   1.245199462   1.33280884   1.105579802   1.393797213   1.644293821   1.24600197   1.054703593   1.762178192       112   1.789966774   0.828706571   1.055070666   1.657863618   2.019257841   1.545807759   0.9780087   0.693709867   0.746219706       113   1.035371601   1.000289519   0.883323683   1.6403011   1.959988419   1.83358425   0.834794063   0.834034146   0.996048432       114   1.272159117   0.832568946   0.726371103   0.772130258   0.510539784   0.533619362   1.032859745   1.093603955   0.535248504       115   1.3997825   0.555289221   0.402252076   0.521526655   0.287437055   0.363937046   0.902819395   1.121152275   0.640152547       116   0.696957353   1.109891003   1.037052084   1.202869447   2.309777246   1.493621516   1.4219039   1.114702142   1.404390798       117   0.636209814   1   1   1   2.092340426   1.815638298   0.750057825   0.434842948   0.434842948       118   0.912637363   0.815846306   0.731215693   0.752362098   1.192027355   0.92652749   1   1   1       119   0.972097408   1.017676925   1.039965541   1.158054878   1.438763128   1.230720164   0.950735234   0.754829879   0.719232135       120   0.876362073   1.261593272   1.211190282   2.08071487   1.836993342   1.421416891   1.025498891   1.230413895   1.337891106       121   1   1   1   1   2.117021277   1   1   1   1       122   1.11523043   1.626336249   1.41122449   0.753109815   0.888483965   1.296890185   1   1   1       123   0.856464201   1.25361497   1.100120499   0.628296002   0.401368018   0.716827332   0.821828418   0.863476425   0.601369074       124   1   1   1   1   1   1   1   1   1       125   1.190873313   1.190002863   0.971530249   0.624575613   0.384505256   0.734609564   1   1   1       126   1.177897813   1.458998182   1.282468188   0.474651586   0.871642093   0.812765098   0.953380911   0.651486369   0.752477281       127   1.107848372   0.426077648   0.330286687   0.272976793   0.236581717   0.215310085   1.001437683   1.187918235   0.645964032       128   1   1   1   1   1   1   1   1   1.200425532       129   1   1   1   1.867021277   1   1   0.963806008   0.963806008   0.963806008       130   0.888252735   0.949186028   0.777303619   0.742848111   1.248854117   0.818476371   0.6917355963   0.862683052   1.136360291       131   2.278902452   0.803321904   0.569454081   0.59568897   0.309265271   0.488067684   1.049837995   1.444243631   0.646639517       132   1.259683375   1.073693065   1.000740436   0.766460455   0.558485656   0.58222341   0.996806204   1.275384521   0.91710493       133   1   1   1   1.129361702   1   1   0.862490632   0.594296083   0.566525975       134   1.048358723   1.072739868   0.801220991   1.875389678   0.448259439   0.569579148   1.010625536   1.440659811   1.402527849       135   1   1   1   1   1   1   1   1   1       136   1.031614754   0.963687489   0.943097297   0.446090585   0.584144645   1.264739675   1   1   1       137   0.77359888   1   1   1   1   1.262234043   1   0.762237039   0.485863441   0.562309402       138   0.800565481   1.153033437   1.212030334   0.792433644   0.822905895   0.811892451   1.055970783   1.123577374   1.769492101       139   0.9471507   0.812765807   0.971363765   1.066664304   1.964240147   1.29327332   1.114698906   1.189583493   1.082587293       140   1.147597254   0.941891468   0.844651819   3.119667503   1.371392723   0.998117942   0.80349083   1.270727675   0.997035166       141   1.235957402   1   1   3.404042553   1   1   0.991649433   0.841470119   0.893301222       142   1.146646143   1.038045261   0.795124084   0.772439051   0.444107358   0.708702307   1.120515138   1.198599187   0.746588342       143   0.735853147   1.109368995   1.145748469   0.906489381   0.905823278   1.034278687   1.042040963   1.212450593   1.492993173       144   0.96263682   1.172281993   1.124575311   0.665345413   0.665345413   0.937146093   1.096840659   1.28483124   0.966149922       145   1   1   1   1   1   1   1   1   1       146   0.671883921   1.055585337   1.264916911   1.26330873   2.066718898   1.237907715   0.812355407   0.638088852   0.703956412       147   1   0.566802261   0.49659253   0.752443341   0.609699403   0.49659253   1   1   1       148   1   1   1   3.736595745   1   1   1   1   1       149   1.351067538   0.557174167   0.368658067   0.279770148   0.260961062   0.189006771   0.910505933   1.271688991   0.448703717       150   1.148165514   1.043416502   1.117094862   0.985795455   1.052124506   1.064970356   1   1   1       151   1.101702128   0.936161737   1.055671746   0.961557614   0.936161737   0.936161737   1   1   1       152   1.195741262   1.006998583   1.271881644   2.979270021   1.350815025   1.472802977   0.668511397   0.848091173   0.960512835       153   1   1   1   1   1   1   1   1   1       154   2.030710807   0.714688137   0.506453031   0.374595437   0.187797179   0.187797179   1.11203966   1.242422096   0.348689802       155   0.77471301   1.189890578   1.122010264   1.85077951   2.108840902   1.516219618   0.861500371   0.758752166   0.895865313       156   0.675584216   1.254257827   1.347588517   0.843126887   0.939255734   0.868067949   0.856950597   0.823136881   1.646946672       157   0.911433085   1.046312498   1.120211459   0.52812628   0.522579204   0.856520606   1.000505051   1.39010101   0.949494949       158   0.949952803   0.961900436   0.915338013   0.890617381   0.664845404   0.553465631   0.852271611   1.067313547   0.491072656       159   1   1   1   1   1   1   0.979392625   0.930919406   1.066577674       160   0.826571404   1.175492075   0.956714858   2.678366138   1.552778262   1.242901933   0.87596822   0.847226719   1.014146597       161   0.876625088   1.207121845   1.054714352   1.115590649   0.924013005   0.820560458   0.894463464   1.047928226   0.65785228       162   0.828413883   0.936973103   0.745305321   0.433025559   0.437619876   0.698425443   1   1.276808511   1       163   1.15661003   0.983357362   1.058076851   0.737760923   0.678869178   0.688929982   0.993022174   0.889491911   1.381144363       164   1   1.170120605   1.162646509   1.053677595   1.930609818   1.256072703   1.06893617   1.156489362   1.146489362       165   1.227443038   1   1.186914894   1   1   1.110744681   1.167122833   1.437505184   1.272621714       166   1   1   1   3.348297872   1   1   0.545835251   1.106366565   0.969479901       167   0.816310201   1.329722501   1.142728185   0.761584754   0.737713139   0.794032096   0.87111915   0.722165509   0.502163734       168   1   0.972682119   0.972682119   0.972682119   0.972682119   0.972682119   1   1   1       169   1.020588063   1.078949093   1.095597776   1.147230098   1.213754931   0.919963129   0.980588728   0.923820121   0.445577932       170   1.17498814   1.009916342   1.190069234   0.744555027   0.819666811   1.020878408   1.128216938   1.353100351   1.461454315       171   1.127352682   1.047322073   1.386891872   1.025321207   1.858495741   1.906395265   1.070953534   1.232812156   1.531424796       172   1   1   1   1   1   1   1   1   1       173   1.357964037   0.992164098   0.861015845   1.955285435   0.737464728   1.0459084   1.279049023   1.227014169   1.314277588       174   1.375857454   0.972884386   1.119368296   0.560190703   0.560190703   0.692669845   0.998514806   1.177852038   1.29657477       175   1   0.877684407   0.877684407   0.877684407   0.877684407   0.877684407   1   1   1       176   0.938137755   1.117156016   1.182594512   2.209748609   1.128094416   1.123296872   1.036936387   1.120902889   0.921745882       177   0.769113113   0.961506644   1.069625224   0.972501754   0.688084442   1.002722599   1.057485751   1.180711674   1.375570543       178   1.185903226   1.123265821   1.1868833   1.058127458   1.218413829   1.060835374   1.231792217   1.310157087   1.404498393       179   0.897717505   1   1   1   1   1   1.019656631   0.77963009   0.77963009       180   0.924014548   0.798191145   0.888093952   1.261406587   1.879859611   1.540226782   0.688898488   0.77511879   0.832354212       181   1.095632006   1.117156016   1.216177317   1.892535022   0.901938208   0.901938208   1.573738528   1.244259925   0.729888728       182   1   0.396112726   0.50754947   0.220388258   1.319656757   1.256635093   1   1   1       183   1   1   1   1   1   1   0.612891986   0.540766551   0.732404181       184   1.010760842   0.983129237   1.088032796   0.811583539   0.901298155   1.174804226   1.263908702   1.344190838   1.728483119       185   1.088733457   0.910154366   0.955318379   2.560057887   0.566811384   0.634647853   0.748684775   1.025447177   0.846108881       186   0.978165939   1   1   1.095212766   1.884574468   1.299680851   1   1   1       187   1   1   1.028510638   1.981808511   1   1   1.193278466   1.206419045   1.006501542       188   0.957037451   1.226900319   1.456499122   0.497789193   0.29353339   0.751430522   1.084459247   1.311380632   0.68833658       189   0.654130793   0.962439299   0.694497357   0.398894642   0.367799748   0.527915649   1   1   1       190   1   1   1   1   1   1   1   1   1       191   0.80143711   0.963343109   0.883502611   0.809241113   0.926990201   0.796849295   1.237863209   1.130307671   0.892862115       192   1   1   1   1   1   1   1   1   1       193   0.834550741   0.776124919   0.601774   1.634620715   1.128014414   0.829668299   1   1   1       194   1   0.942406489   0.909418657   0.884632717   3.616584047   1.972780532   1   1   1.30712766       195   0.702598088   1.013515601   1.421995675   0.774482546   1.609051591   1.456518381   0.7808011782   1.017193764   0.700935412       196   1   1.135433202   1.136268694   0.785362186   1.385746512   1.507895396   1   1   1.433617021       197   0.89311261   0.918840859   0.821940888   1.008857225   1.27534418   1.062578223   1   1   1       198   1.080507225   0.998936924   0.886428065   0.860028349   0.878809355   1.195694543   1   1   1.124680851       199   0.73260500   1.125234365   1.13313708   0.856489513   0.901890694   0.956508788   0.99801919802   1.002271404   1.53960396       200   1   1   1   1.163723404   1   1   1   1   1       201   1   1   1   1   1.124361702   1   1   1   1       202   1.602981384   0.892174556   0.69815373   0.89988991   0.265047194   0.450391633   1.034285568   1.38302405   0.34628988       203   0.679492901   0.949551854   1.151947598   1.500657442   2.511369531   2.073006261   0.773748968   0.506079468   0.96198938       204   1.376929815   1.459472196   1.320040057   0.553722903   0.628946748   0.805136664   1   1   1       205   1.056577971   1.020698772   0.91898017   0.520944287   0.813673277   0.57170916   0.964910837   1.018052126   0.412866941       206   1.124255319   0.95588059   1.26927227   0.665387843   1.529372977   1.373516365   1   1   1.080851064       207   1.010221236   1.170120605   1.204178699   1.340920673   0.798369288   0.798369288   0.8546567   1.339243082   0.352328024       208   1.304468085   1.241973841   1.403601155   1.495583489   1.081195855   1.464582979   1.268103034   0.934062827   1.644725309       209   1.052688489   1.154238152   1.19279769   1.147698318   1.044419908   1.023186683   0.825490085   0.858426078   0.994407096       210   0.975843284   1.001454636   1.007190059   0.719504592   0.390673704   0.550268069   1.256771919   2.014665812   0.753325854       211   0.985621219   0.886284062   0.896787943   1.207388238   2.492109403   1.773177044   1.140080093   0.96637744   1.058318038       212   1.263901413   0.926342561   1.004450748   0.756847305   0.898415338   0.968233395   1.261029829   1.363955994   1.275377112       213   0.833457483   1   1.395106383   2.874680851   1.586808511   1.254468085   1.049859104   0.923870557   0.857967458       214   1.453651567   0.933982304   0.815135941   0.731390451   0.456645908   0.569470141   0.939829954   1.30520506   0.6316881794       215   1.390943878   1.102339787   1.378041205   1.888290713   1.752200021   1.009162439   0.95323675   0.841665138   1.139116083       216   1.064770007   0.747079186   0.954601183   1.238497043   1.112072696   0.972739074   1.158106039   1.044907082   0.504449319       217   0.653453711   0.937971118   0.883463849   0.410367452   0.661429758   0.800465624   1.085875417   1.118943861   1.092369478       218   1.829529882   0.971401542   0.826037654   0.673377547   0.425422724   0.669405449   1.078100834   1.444042684   0.797569192       219   1.091290767   1.041766154   0.892441427   0.987141223   0.649498831   0.67376759~   1.028442724   1.039232746   0.738128537       220   0.927886213   1.214646064   1.098391344   0.706666244   0.92705524   1.167020973   1.008191489   1   1.653191489       221   1   1   1   1.587765957   1   1   0.962163782   1.040008991   0.234759372       222   1.003617021   1.102765957   1.041914894   1   1   1   1   1.187021277   1       223   0.970436561   0.947328002   0.836634712   0.657274509   1.307160638   1.62949526   1.090332129   0.99026667   0.997467058       224   1   1   1   1   1   1   1   1   1       225   1   0.915215067   0.324238557   0.324238557   0.324238557   0.324238557   1   1   1       226   1.032953996   1.057207501   0.971135914   0.308965948   0.535675404   0.545056942   1.152582307   0.990148821   0.812833281       227   1.090228844   0.780110132   0.889432383   0.600672198   0.210617132   0.525755098   1.262090424   1.952521799   1.004455883       228   1.06614937   0.920856463   0.915107058   0.858207772   0.547898493   0.7370341   0.958659165   1.219149342   1.067757009       229   1   1.121125337   1.453672507   0.791778976   1.598214286   1.596192722   1   1   1.102765957       230   0.782015943   1.114766759   1.019616929   1.383070745   2.046184739   1.442539388   1   1.125744681   1.872553191       231   1.067234607   1.355688771   1.301875965   1.303279642   0.523734558   0.979169736   1.177523718   0.930142001   1.03812581       232   0.600271657   0.94049135   0.894306923   2.298506072   2.557722769   1.184489238   0.962828685   0.847205522   1.066588398       233   1.854810375   1   1.237340426   1   1.273723404   1.272553191   1   1   1       234   1.082495478   1.005513614   0.802570193   0.568368818   0.44825685   0.788362032   1.075666925   1.141057225   0.892869712       235   1.189731228   1.024649196   0.912182883   0.582589908   0.667224236   0.88825388   1.248596112   1.168552916   1.628941685       236   0.93973822   0.830813295   0.864717245   0.626124026   0.732764937   0.819423167   0.979822355   0.946192946   0.605226678       237   1.088899568   1.001359291   1.113654301   0.962772954   0.842059107   1.049942997   1.062567678   0.952196075   1.08985025       238   1.18750952   0.969870875   1.121347127   1.42950993   1.807218908   1.465151401   0.845035284   0.716159384   0.873904056       239   1.262020721   1.093718777   1.164857124   0.837340971   0.626124026   0.996602944   0.7857792   0.830128322   0.919262787       240   1   0.883161512   0.771773907   0.556938026   1.158371845   1.106647707   1   1   1       241   1   1   1   1   1   1   0.896689879   1.037012306   1.200610512       242   1   1   1   1   1.158829787   1   .003829787   1.39920429   1.018197544   1.402456322       243   0.827739001   0.946950925   0.612262783   0.21520307   0.172745679   0.351867521   1.027419773   1.738084941   0.813078453       244   0.725769453   1   1   2.592553191   1   1   0.856167927   0.700403229   1.069797236       245   1.594680663   1.080780452   1.308123632   0.961068563   1.091037564   1.804932531   1.084111572   1.527985652   0.876059125       246   1   1.034980566   0.996761059   1.445030539   1.971589857   1.457153433   0.972459193   1.020689192   1.07684557       247   1.100172853   1.142689615   1.335819166   1.131376969   1.398716355   1.521105002   1.025552608   0.979126685   1.265488688       248   1   1   1   1   1.740531915   1.326808511   0.721080086   0.721080086   1.124271249       249   1.050204746   1.066043462   1.096734248   1.477285419   2.405414593   1.783707661   1.020776567   1.277836265   1.150606886       250   1.110754102   0.725352789   0.631698186   0.803283095   0.928616684   0.927023135   1.255770547   1.165743794   1.198759825       251   1.346664046   0.936611816   0.83793201   0.866820689   0.554778632   0.549148946   0.926231702   1.129615802   0.74886234       252   1.106321401   1.112438189   1.187980221   0.715100799   0.779307722   1.072499049   1.299580543   0.842004563   0.837809993       253   0.891169266   0.946127567   0.96447321   1.395948067   1.853102965   1.540387436   1.032808536   1.032880903   1.103443077       254   1.011675559   0.972804566   1.142674121   1.706848358   1.302818542   1.350687165   1.262669903   1.031116505   1.256990291       255   0.667343486   1   1   1.296489362   1.776382979   1.200425532   0.732801786   0.525051826   0.766640089       256   0.633708385   0.9131443   0.964366892   1.018011709   1.141304098   1.16227758   1.209514622   1.313139724   1.421222583       257   1.496940354   0.922831588   1.045136241   2.331692436   1.845385842   1.183318311   1.150102722   0.958739942   1.453561034       258   1.446104038   0.743960035   0.698843751   0.899291574   0.202296504   0.382629925   1.213028292   1.318651764   0.3514146       259   1.027720664   1.030213753   0.979188867   0.458847866   0.436500972   0.651194133   0.962612164   0.95789903   0.66418925       260   1.443682335   1.138355699   1.054272125   1.410225922   0.798369288   0.798369288   0.963570128   1.638737098   0.954219794       261   1.043716203   1.123119015   1.215116279   0.642954856   0.937688098   1.01751026 1   1   1       262   1.223942958   0.846782605   0.868461105   0.928652549   1.0352913   1.154337631   0.943020446   1.12131744   1.619199544       263   0.749276338   1.054635108   1.238001315   1.518343195   1.43182117   1.263773833   1.024516161   0.911138268   0.811776736       264   1   1   1.141382979   1.078085106   1.435212766   2.093297872   1.026990553   1.239786529   1.13390995       265   0.991665788   0.962475993   0.933003398   1.484118777   2.121435958   1.195449845   0.853627479   0.994779232   1.130360042       266   1   1   1   1.117978723   2.042978723   1.057234043   0.95100029   0.681356915   0.681356915       267   1.161680401   0.963312154   0.963312154   0.963312154   0.963312154   0.963312154   1   1   1       268   0.554846449   1.041936157   0.836386397   0.666054663   1.203588567   0.779386605   1.015699201   0.6471311125   0.703167775       269   1   0.877684407   0.894771242   0.877684407   1.219047619   0.998412698   1.16216746   1.105656679   1.363791655       270   1   1   1   1   1   1   0.942544871   0.942544871   0.942544871       271   0.799705677   1.103543666   1.150517343   1.241655498   1.693486302   1.320291642   0.918950106   0.659507776   1.021364725       272   1   0.936161737   0.936161737   0.936161737   1.64067324   1.031470969   0.87832818   0.953221968   1.180238895       273   1   1.577220481   1.370323929   3.405015674   1.284952978   0.982236155   0.754782609   0.838015608   1.325529543       274   1   0.951292728   0.932022853   0.910235306   0.910235306   0.910235306   1.135146981   1.350311492   0.679710735       275   1.788300501   0.779022546   0.59312888   0.848924054   0.123670821   0.340559212   1.219077151   1.657638964   0.627698592       276   0.843486809   1.102765957   1.575   2.613085106   1.704893617   1.236489362   1.085402007   1.08383041   1.045719184       277   0.867007222   1.031428955   1.029259127   1.209108805   1.823438618   0.885670186   1.04416511   0.89875998   0.798369288       278   0.648100835   1.164224446   0.839885633   0.905468192   1.342655468   0.872944961   0.906410088   0.955536582   0.904439774       279   0.780706182   1   1   1.072446809   1   1   1   1   1.025212766       280   1.095666974   1.214365119   1.287240613   1.765686759   2.26117836   1.760251976   1.289359581   1.007276352   1.617542985       281   2.0997641   1.983105335   2.530300958   3.218194254   3.086730506   3.73372093   1.335296283   1.600767653   1.177401546       282   1.402008839   1.1285118   1.217290095   0.754535238   0.754535238   1.001123776   1.036352201   1.614779874   1.310314465       283   0.897984491   1.08449425   1.301486597   2.139577128   0.381947134   0.978495773   1.139385843   1.101386075   0.72836569       284   0.654109627   1.020689878   1.133837649   1.370542786   1.926841884   0.998868522   0.952308362   0.744120209   1.225783972       285   1   1   1   1   1   1   0.993919722   0.641217884   0.90779007       286   1.215417517   0.971076339   0.864706812   0.881460408   0.742848111   0.742848111   1.20869943   1.44535097   0.849763445       287   1.24625864   0.886822366   0.84065687   0.596436431   1.047182982   1.022124417   1.35875364   1.053391145   0.52728007       288   1   1   1   1.5392553191   1   1.00610977   1.367305026   1.27370745       289   1   0.919810563   0.881762723   0.890993739   1.882324611   1.369963076   0.769862532   0.621766437   0.962141508       290   1.502584661   1   1   5.887659574   1   1   0.884616237   0.820341763   1.178040293       291   0.792847503   1.122021277   1   1.867021277   1.1588297871   1.184021348   1.016773772   0.889064372       292   0.880299411   0.892853792   0.903434975   1.265718009   1.572061506   1.195162888   0.923096201   0.831055569   1.201473586       293   0.861136091   1.306007841   1.510896055   0.580263483   0.858121711   1.040476106   0.995046093   1.219178082   1.085207203       294   0.883870172   1.200896283   1.294156343   0.73998191   0.867119833   0.891185177   0.948332279   1.061154289   1.184322825       295   1   1   1   1.02712766   1   1   1   1   1       296   0.749362245   1   1   2.137446809   1.181808511   1   1   1   1       297   1   0.73151751   0.73151751   0.73151751   0.73151751   0.73151751   1   1   1       298   0.974832838   1.083510638   1   2.436489362   1   1   1.225801728   0.997949919   1.008273539       299   1   1   1.059893617   3.832765957   1.158829787   1.057234043   0.971768325   1.105070786   1.018126488       300   1   0.42478196   0.42478196   0.42478196   0.42478196   0.42478196   1   1   1       301   1.60447524   1.621627054   0.517712678   7.937691573   0.472338073   0.472338073   0.927142135   1.119997472   0.970427163       302   1   1.076460142   1.160220994   1.010359116   1.255919495   1.416436464   1   1.125744681   1.391595745       303   0.976974088   0.88589555   0.869038862   0.776664215   1.070215766   1.339738875   0.861701374   1.154023233   1.224093356       304   1   1   1   1   1   1   1   1   1       305   1.825939647   0.997632256   1.025247727   0.832722117   0.444067596   0.520908505   0.889901543   1.218541186   0.637514044       306   0.926558293   1.085760561   0.994264928   0.818256644   0.683880732   0.744098983   0.850403317   1.093196645   0.329819713       307   0.891841335   1.267662399   1.209103841   1.930930931   2.605579263   1.468942627   1.163033556   1.227772301   1.168108957       308   0.849525531   1   1   7.322340426   1.170319149   1   0.89881055   1.022776245   1.057231512       309   0.870979279   1.34261713   1.424699056   1.108564995   1.278704425   1.100355071   0.862149894   0.847112723   0.661495004       310   0.932356769   1.19745708   1.109585564   1.006553443   1.324372346   1.229993539   1.07556662   0.968310772   1.420413879       311   1   1.106922851   1.211938985   2.115869757   0.689351716   1.033880903   1.263617021   1.047340426   1       312   1   1.073829787   1.19606383   2.349255319   1.101382979   1   0.554299308   0.610376072   0.577740358       313   1   0.275098197   0.22932982   0.22932982   0.22932982   0.22932982   1   1   1       314   1   1   1   1   1   1   1   1   1       315   1.436797975   1.02479204   0.927418039   1.020714402   0.932392758   1.100717664   1.078406072   1.417077799   1.477419355       316   1.385204082   1.230957429   1.08024792   0.766595988   0.766595988   0.789920078   1.468191489   1.737978723   1.036382979       317   0.451528634   0.787155323   0.820942408   1.10617801   1.010471204   0.960139616   1.29847868   1.298978644   1.264195415       318   1   1   1   1.848085106   1.610319149   1   0.797340945   0.706076767   0.706076767       319   1.150796693   1.217403904   1.319756567   1.610032405   0.496851701   0.640777722   1.244050955   1.593019108   0.760840764       320   0.513400137   1.099541304   0.788592618   0.878166931   0.953916063   0.594547091   1.002166303   1.166762309   0.242669       321   1   0.308549986   0.126905791   0.183590306   0.108982216   0.101068748   1.084809875   0.935695799   0.935695799       322   0.933095096   0.748646066   0.748646066   0.760512902   0.748646066   0.791494106   1   1   1       323   0.961538462   0.839885633   0.839885633   0.967744818   0.839885633   0.839885633   0.985683885   0.909266783   0.909266783       324   0.716011072   1.045011371   1.465470266   1.076760262   1.372430254   1.327306298   1.038080433   1.059479655   1.245318352       325   0.702318006   0.962404779   1.037047186   1.413273415   1.903271771   2.180522826   1.210393027   1.080019734   1.479526394       326   0.657369126   0.890000632   0.784764767   0.91562981   0.415432023   0.649245917   0.961985616   0.983453199   0.508300438       327   0.542318122   1   1   1   1   1   1.157338649   0.468477448   0.468477448       328   1.005589028   1.323831022   1.286681716   2.356788133   1.069719445   1.328152209   1.211938403   0.950785839   0.503458599       329   1   0.951292728   0.910235306   0.929795681   1.117555921   0.910235306   1   1   1       330   0.764896454   1.107748336   0.940524928   1.909431119   3.084566118   1.658369961   1.436152271   1.130385897   1.607075453       331   1   1   1   1   1   1   1.129397669   0.615401372   1.198344407       332   0.991997216   1.076479716   0.936057538   0.476785142   0.378309811   0.650385477   1.106804944   1.11376616   0.430373633       333   1   1   1   1   1   1   0.673262216   0.547487956   0.540605643       334   1.094148936   1.293625914   1.347335423   0.982236155   0.982236155   0.982236155   0.884456154   0.884456154   0.886902522       335   0.841992118   0.98887379   0.936640054   0.887973501   0.998556141   0.979955835   1   1   1       336   1.28716161   1.148311848   1.39907919   1.496009822   0.956414979   0.902516882   1.277102804   1.420093458   1.837476636       337   1.239749577   1.400180397   1.661062029   0.608423146   0.46292613   1.01706832   1.346160298   1.280135539   0.963230114       338   1.290655749   1.124915505   1.11457577   0.754813109   0.610106902   1.005545402   0.994226652   0.931491945   0.720931457       339   1.017719569   0.966750652   0.887069198   0.427247368   0.422928102   0.588005039   0.854372543   0.914302412   0.610243332       340   0.853139498   0.850509599   0.994579365   1.165895269   1.641380296   1.675750698   0.767628102   0.734987254   0.753425014       341   0.897915863   1.006763681   0.963312154   2.008710801   2.539557286   1.43594999   0.80949364   0.689945904   1.166820995       342   0.800829154   0.887750302   0.729766215   0.944059234   0.702624205   1.072058252   1.381478085   1.240418118   1.530166881       343   0.576757884   1.095707599   0.936161737   0.936161737   0.936161737   0.936161737   1.134297681   0.543938571   0.503451485       344   0.950848076   1.200970055   1.346478279   1.425347954   2.29122733   1.822718965   0.885188733   0.621230121   0.95807626       345   1.109281052   0.901648582   1.005451591   0.841536929   0.627326099   1.148359281   0.771106445   1.163646629   1.367644724       346   1   1   1   1.157978723   1   1   1.000383757   0.621790399   0.774455763       347   0.783847058   0.734138057   0.782118161   0.624469247   1.847992236   0.992357152   1.065714792   1.301791415   1.212575381       348   0.871690504   1.20803583   1.368233156   1.974879917   1.695767883   1.119304167   0.941589595   0.728834893   0.974552619       349   0.81952862   1.169768108   1.190724306   1.985113083   1.594732322   1.189636416   0.937530374   0.886562449   1.07077191       350   1.163830439   0.900792514   0.948152392   0.966262453   1.001527738   0.840415035   0.853625105   1.061753036   0.767055429       351   1.452159592   0.743307778   0.867549498   0.5266011   0.359508506   0.686517463   0.999440881   1.662818615   0.56921559       352   1   1   1   1.106595745   1   1   0.707296701   1.011842969   0.822623948       353   1   1   1   1.943297872   1.147340426   1   1.11185   0.84805   0.86045       354   1.068264399   0.898347626   0.821323991   1.368803598   1.436937879   1.30140138   1.076373491   0.829853412   0.445306726       355   0.780587924   1.144569918   0.859303589   0.752853893   0.393581046   0.68845941   1.052631579   1.201913442   0.805315646       356   1   1   1   1   1   1   1   1   1       357   0.757855715   0.900445376   0.763601432   0.879966815   1.140730067   0.77827264   0.860733441   0.816702008   0.753897967       358   1.392420293   1.350475466   1.232940281   2.140129327   1.513883606   1.033320654   1   1   1       359   1.099307637   1   1   1   1   1   1   1   1       360   0.908153117   1.282813679   1.314013913   0.499916185   0.509093957   1.110699019   0.875420875   1.191646192   1.172354172       361   0.813409355   1.221319556   1.201712429   0.812983789   1.190722214   1.377939243   1.100789314   1.032695811   1.1423436551       362   1.070081398   0.828597737   0.947119179   0.541568008   1.232131895   1.233008857   1   1   1       363   1   1   1   1.296489362   1   1   1   1   1.987340426       364   1.084540489   1.294933562   1.1677356   1.503544358   1.791358517   1.322551938   0.853420773   0.880024814   1.332435307       365   1   0.830232817   0.713267238   0.543667149   0.769633508   0.911217556   1.468191489   1.602765957   1.454574468       366   1.212853084   1.269082359   1.337694441   0.441336067   0.483118293   1.09713011   1.340722496   1.091885605   1.338464696       367   1.358742707   1.051496149   1.028610865   0.835917797   0.489400859   1.016341763   1.062207684   0.84448079   1.178818398       368   1   1   1   1   1   1   1.323323479   2.150044085   1.161402417       369   1.166799643   0.94137418   0.983910959   4.27175051   0.713372638   0.838778996   0.722301886   0.812775628   0.865533941       370   1.209814452   0.991910278   0.985263835   2.595615003   0.60965251   0.717990439   1.395051125   1.154569381   0.881961592       371   1.071595745   1   1   1   1   1   1.145595855   0.347890452   0.484122872       372   0.971375426   0.898197199   0.708718328   0.745226069   0.509424664   0.800583138   0.832904162   0.828690482   0.44009551       373   0.908291738   1.11114937   0.979477997   0.942083879   1.235658701   1.163143034   1   1   1.17893617       374   1.252272397   1.069077926   0.998358983   0.441477802   0.272697033   0.644786446   1.285152864   1.274345489   1.068311853       375   1.850711601   0.799503079   0.972669331   0.989377408   1.426614094   1.806416766   0.948859935   0.676547231   0.721009772       376   1   1.089837528   1.111420835   1.793883402   1.93501115   1.261070405   0.808115543   0.995787483   0.908872077       377   0.916495081   0.944628016   0.949467641   1.100697574   1.9155902671   1.337705684   0.966339467   0.737193498   0.87445853       378   1   1   1   1   1   1   1   1   1       379   1.416540671   1.102765957   1.376382979   1   1   1.012659574   1   1   1       380   0.896221173   1.089229792   1.199337358   1.611764172   1.934825035   1.207053057   0.822564663   0.670482113   1.038815048       381   0.636209814   1.929042553   3.302234043   6.955212766   1.681170213   1   1   1   1       382   0.688394031   0.956948292   0.807363804   0.839950754   1.138504155   0.990304709   1.008191489   1   1.508106383       383   1   1   1   1   1   1   0.686673165   0.506510235   0.772838045       384   1   1   1   1.198085106   1   1   0.911148649   1.433004158   0.869984407       385   1.258908698   1.133128531   1.363820049   0.820213599   0.98696961   1.14176735   1.005333792   0.915290204   1.455838495       386   1.034021238   0.892464956   0.872071251   0.454632863   0.767673701   0.745382319   0.728719492   0.628552324   1.425743898       387   0.919223206   1.001594833   1.001914942   0.667314508   0.433022751   0.771064365   1.135632345   1.279908788   1.017042624       388   0.851653483   1   1   2.052765957   1   1   0.933880996   0.786216928   1.142245485       389   0.844941039   0.969870875   1.016914596   0.709808956   0.838858265   0.896851167   1.011521441   1.019609339   1.178238975       390   1.284091547   1.127131938   1.064550582   1.159340476   0.933713828   0.919428591   1.175109346   1.32934206   1.084313056       391   1   1   1   1.661170213   1   1   1   1   1       392   0.835988888   1.04666923   1.17079007   0.949177456   0.916600436   1.130521728   1.02395432   1.028571125   1.007609769       393   1.023439523   1.056842756   0.725980846   0.725980846   0.824606117   0.754556688   0.6118221   0.949142914   0.712467003       394   0.818195266   0.91490272   0.706285016   0.896118977   1.008169502   0.480167057   0.688183737   0.713837886   0.601369074       395   1   1.535531915   1.555851064   1.599893617   1   1   1   1   1       396   1   1   1   1   1   1   1   1   1       397   0.986647626   1.003502962   1.003248201   0.825234062   1.049232533   1.24164066   1.109353508   1.235534159   0.946309033       398   0.993194053   0.876555781   0.905250387   0.644940802   0.596347368   0.767388455   0.671020071   1.174388232   0.676862799       399   0.989700196   1.229515443   1.582518371   1.372921156   2.046190397   1.890546439   0.814625629   0.65972613   0.994776561       400   1.119118523   1   1   1   1   1   1   1   1.17893617       401   1.138726636   1   1   1   1   1   1   1   1       402   1   1   1   1   1   1   1   1   1       403   1   1   1   1   1   1.039361702   1   1   1       404   1.261545413   0.961923848   1.13421128   0.697795591   0.629888348   0.997537933   1   1.20212766   1.30712766       405   1.321638892   0.76947241   0.946005098   0.840744651   0.33895512   0.719133816   1.015603217   1.203538874   0.944530831       406   0.775527654   0.885811294   1.062365976   0.886436741   1.421908506   1.383488206   0.66494772   0.489437371   0.994203002       407   1.10125401   1.068344334   1.238758251   0.385313531   0.478788504   0.762066832   1   1   1       408   1   2.112234043   2.323191489   3.055425532   1.516595745   1   1   1   1       409   0.91112949   1.111936029   1.110659144   0.785217845   0.937758182   0.881069549   0.952445479   0.791489815   0.867141313       410   1   1   1   1   1   1   0.695634077   0.560583312   1.207568393       411   0.680095244   0.778984006   1.138062484   1.064556228   1.254412862   0.90014088   1.165278904   1.147630978   1.236828531       412   0.967318943   0.810306327   0.788834812   0.538219296   0.538219296   0.564214143   1   1   1       413   0.855890814   1.257939472   1.211351755   0.998150717   1.172552367   1.294285003   1   1   1       414   0.910166542   1.0339565G5   1.359023274   1.63801984   1.841949638   2.134586036   0.942946248   0.887360117   1.18651012       415   1.122082766   1.064908722   0.860254083   2.032454361   2.034803032   1.288192591   0.957985224   0.776772768   0.846509701       416   0.900566496   1.09606502   0.982545745   1.045434358   1.503330965   1.202300586   1   1   1.444042553       417   0.992327163   1.024110032   1.078883495   0.898058252   0.820064725   0.933495146   1.012591815   1.158160832   1.903462749       418   0.98046046   0.921979746   0.946560167   0.848785242   0.903199734   0.709432796   1.032142028   1.29890926   1.904618241       419   1.22671022   0.949252113   0.927018844   0.550725293   0.580143703   0.905689367   0.993762554   0.993762554   0.993762554                   U   V   W   X   Y   Z   AA   AB   AC       1   DR.JRF   DR.JRFnCMS   LC.CMS   LC.IMP   LC.IMPnCMS   LC.JRF   LC.JRFnCMS   MG.CMS   MG.IMP               2   1.611129651   1.156933089   0.928919578   1.433143786   1.512059671   1.589203161   1.703020456   1.042762294   1.038673619       3   1.232021277   1   1   1   1   1   1   1   1       4   1.342021277   1.421170213   1.410920595   1.21750798   0.934493376   0.789073755   0.739103415   1.026808511   1       5   1.042978723   1.243510638   0.965282552   0.932283789   1.001 993675   1.005499794   0.717998075   1   1       6   1.372321998   1.765429848   0.936288089   0.906759003   0.852022161   1.087977839   0.939778393   0.871344323   0.916130903       7   1.378297872   1   1   1   1   1   1   1   1       8   1.307197592   1.105090312   0.827537635   0.894885113   0.827537635   0.827537635   1.004225724   0.857719418   0.754092769       9   2.14092585   3.001736993   1.236828394   1.089150874   1.270221089   1.304873591   1.023718612   0.990974006   0.92388771       10   0.815831495   0.957264228   0.870267347   0.940529542   1.030726833   1.099495184   1.808195539   1.124058627   0.871162503       11   1.584361702   1.537553191   1.229574468   1   1.464361702   1.351914894   1.341489362   0.938704225   0.781521127       12   1.253262813   1.25276816   1.863879575   1.351287722   1.659984305   1.477491617   2.075408433   0.986408256   0.883513718       13   0.998088998   0.855400855   1   1   1   1   1   1   1       14   1   1   1   1   1   1   1   0.80129047   0.91943128       15   2.113429664   1.655843604   1.154433323   1.978970782   2.296683854   2.702102922   2.668385401   0.88520216   0.720711954       16   1   1   1   1   1   1   1   1   1       17   1   1   1   1   1   1   1   1   1       18   2.120359367   1.521937539   0.774219681   0.750917322   0.732856802   0.716511794   0.915034548   1.126663586   0.850600739       19   1.119017886   0.992487109   1.104549758   0.913738974   0.821248816   0.692804106   0.97931928   1.196504562   0.94600479       20   1   1   1.185009336   0.57113897   0.67607362   0.802133902   0.501467058   1   1       21   1.97763864   2.017531306   0.883091149   1.273147592   1.374564669   1.993154798   1.795784796   0.962793418   0.972991531       22   1   1   0.534945144   0.77021536   0.632629013   0.705526209   0.617106867   0.872813368   1.366414902       23   1.279747183   1.542639919   1   1   1   1   1   1.055759121   1.046120758       24   1.224330357   0.892485119   0.466310311   0.552445257   0.594223285   0.749613166   0.652318657   0.920070679   0.744413263       25   2.283471074   3.206198347   1   1.253404255   1   1   1.06606383   0.968927355   0.977617764       26   0.866758875   0.904564315   1   1   1   1.233617021   1.050851064   1.210088404   1.138429537       27   1.286849526   1.543194053   0.883209621   1.257540167   1.742553791   2.083623039   1.81574744   1.021905762   0.940119062       28   1   1   1   1   1   1   1   1   1       29   1.025466143   0.754048086   1.601727147   1.373797485   2.177726073   2.428296568   2.257461184   0.882703383   0.962997286       30   1   1   2.772124469   2.532634134   3.809395857   4.503857155   4.162953974   1   1       31   0.529070749   0.529070749   1.282828283   1.227144325   1.30671118   1.415254237   1.509972607   0.929256339   0.722885148       32   1   1   1.156779152   0.824906929   1.090068452   1.195268404   0.980785397   1   1       33   0.464979314   0.62404478   0.856679614   0.931557836   1.009714008   0.755246481   0.562665219   1.094315041   1.997275957       34   0.8406037   0.718787963   1.001684042   0.836701417   0.942502005   0.699906442   1.023509757   1.211821725   0.83589065       35   1.232098537   0.835969624   0.912567364   1.447596465   1.757016598   1.728950205   2.065186463   1.00325032   0.771899393       36   0.949494949   0.949494949   1   1   1   1   1   0.894378651   1.002920529       37   0.608917398   0.563436563   0.595804019   0.609875135   0.670342904   0.616720543   0.790898431   0.946547782   0.795976223       38   1.231274539   1.500679553   0.500201045   0.651655274   0.733246214   0.675981772   0.647533843   0.888424522   0.738381857       39   1.278085106   1   1   1   1   1   1   1   1       40   0.53972894   0.615997874   1.350202545   1.386717636   1.190506076   0.74861642   1.017801107   1.153621068   0.885241405       41   2.152956094   1.77746077   0.745854162   1.298659049   1.199079584   0.864000635   1.355946997   0.886341129   0.716081359       42   1.430358476   1.572115385   0.569617515   0.907255971   0.934795777   0.798221703   0.910263067   0.789662265   0.66654502       43   1.074961405   1.084966682   0.55864057   0.708086785   0.702260658   0.752935822   0.718585951   0.98219956   0.878525901       44   1.465497037   1.356379951   1.380028055   1.598741328   1.503279372   1.316525761   1.422451378   0.928481807   0.753615532       45   1   1   0.930600931   1.765468765   1.46955747   1.850806851   2.082566083   1   1       46   2.283784687   2.959946506   0.756478352   1.012795751   0.804764204   0.899163045   0.907130211   0.843546089   1.154068852       47   1   1.320106383   1   1   1   1   1   0.912354135   1.058219178       48   0.531043444   0.628382577   1.36704157   0.985466317   0.918726981   1.058943996   0.759979521   1   1.046808511       49   0.419417391   0.534772511   0.617922839   0.436102741   0.27783982   0.292937061   0.396521208   1.22504075   1.351212306       50   0.793095718   1.033325861   1.180851064   1.639255319   1.63606383   2.131914894   2.186170213   0.949168392   1.055974885       51   1.098097079   1.295105322   0.583356471   0.604260045   0.668002063   0.601800801   0.667883037   0.916693864   0.836569843       52   1   1   0.451640801   0.970739442   1.177917648   1.116369577   0.904819103   1   1       53   0.553450259   0.366885023   3.54637032   1.360416549   0.740186351   1.211808509   1.22792992   1.234755417   1.567946045       54   1.432446809   1.148723404   1   1   1   1   1   1   1       55   1.460350173   1.265138618   0.712224067   1.077163508   1.637819887   2.030889822   2.205435632   0.979894018   0.973177487       56   1.477340426   1.43787234   1   1.04287234   1.017340426   1   1   1.245265503   0.872632752       57   1.614341247   1.670414646   0.899364924   1.315974597   1.246116268   1.307718613   1.312652662   1.128036015   0.97430387       58   1.7171089151   .776710706   0.988396636   1.007054574   1.283988938   1.922027202   1.668480163   0.787709938   0.777748574       59   1.69731947   1.21406086   1.268063584   1.489956647   1.932153179   1.726445087   2.051372832   1   1       60   1.240213362   1.946388211   0.947580645   0.947580645   0.947580645   0.947580645   0.947580645   1.142158338   1.222757375       61   1.160330579   1.298347107   0.647796045   0.746771503   0.963831308   0.826495116   0.748248749   0.789441914   0.810678812       62   1   1   1.12563   1.319722992   1.947146814   1.475844875   2.344487535   1   1       63   1.011841846   1.20771097   1.404916619   0.914558493   1.640632557   1.584821147   1.628898282   1.104914617   1.114362407       64   1.019390376   1.010250963   0.508779856   1.163825526   1.211681239   1.458139989   1.269892053   1.161122904   0.864404188       65   1.167540936   1.379394291   0.630957175   0.951738488   0.822862129   1.309101893   1.155457108   1.110648494   0.956544509       66   0.602417457   0.728756517   1.254577995   1.025847777   1.2860211   0.860870384   1.034118312   1.04833124   1.154675235       67   2.723510638   2.034148936   1.180851064   1.329255319   2.219787234   2.611808511   2.302340426   1.095943236   0.952182631       68   1.262230194   1.177871235   0.497450765   1.100803092   0.997067546   0.969542471   0.812889466   1.07197757   1.02605501       69   1   1   0.496881277   0.754202347   0.734749974   0.72259224   0.617295697   1   1       70   1.575425532   1.62   1   1   1   1   1   0.847556122   0.748288489       71   1.049708481   1.185550279   1.328915744   0.670949983   0.498046324   0.474843907   0.365505203   1   1       72   1   1   1   1   1   1   1   0.815684949   0.794388574       73   1.356760259   1.156025918   1.296123599   0.844804788   0.654186095   0.654186095   0.654186095   1.030224435   0.817131791       74   1   1   1.703444391   1.084178336   1.162079511   0.756478352   0.771849348   1   1       75   2.20031991   2.405626647   0.96165356   1.199248382   1.317767416   1.708608811   2.048924769   0.996082699   0.762948857       76   1.575906613   1.524088496   0.890982584   0.7496882   0.999924867   1.091481465   0.670934199   0.831016278   0.952419733       77   1.537370539   1.597928623   1   1   1   1   1   0.914837223   0.95303947       78   1.957809144   1.93840135   1   1   1   1   1   1   1       79   1.820021564   1.504188438   1.227530078   0.940299262   1.11257709   1.147811141   1.026488727   0.981981335   0.751830581       80   0.73804107   0.499550979   0.636327024   0.886494832   0.951201504   0.871526379   0.985568533   0.868985849   0.897287736       81   1   1   1.173013608   0.552842406   0.515803336   0.765144864   0.515803336   1   1       82   1.241276596   1.157340426   1   1   1   1   1   1   1       83   1.834029518   1.865868375   1   1   1   1   1   1.082630945   0.707405178       84   1.69970487   2.292097065   0.767379176   0.783238262   0.724942017   0.591299442   0.680749702   1.217244554   0.984657871       85   1   1   0.453024332   0.479170576   0.293988866   0.478763996   0.293988866   0.946036904   0.866194731       86   0.958671501   0.592572999   1.013239287   0.944159879   1.610882526   1.480952781   1.997200996   0.927551583   1.044476389       87   1.006635809   0.891123582   0.99263376   1.152486812   1.411567445   0.895685757   0.829559156   0.831346969   0.891501584       88   1.826611778   1.820401898   0.404818059   0.641004043   0.668463612   0.871226415   0.761623989   1.031948593   0.896596977       89   1   1   1.105901563   0.692725516   0.733413309   0.555366723   0.5147789   1   1       90   1.625949853   1.253066568   1.121393901   1.031229966   0.855160729   0.556552798   1.013142229   0.911511355   0.818444672       91   1.731089043   1.479687352   1.056676273   1.193497632   1.269849945   1.370250754   1.60469045   0.949679338   0.882079895       92   1.111623345   0.829671408   1.25393617   1   1.420957447   1.816276596   1.425   1.023030104   1.065964797       93   1.897227128   1.77455846   1.184923072   1.198903748   0.949402439   1.193144958   0.931518968   0.983965903   1.134486627       94   0.881034075   0.799574065   1   1   1   1   1   1.294787234   1       95   1.413463558   1.207834489   0.693984525   0.840502538   1.259963391   1.0104002   0.91039188   0.8433033   0.989184842       96   2.95755751   2.621054856   1.186911575   1.103101348   1.033228724   1.573149345   1.628161344   1.030046108   0.861105819       97   0.382084802   0.462816562   0.722820247   0.842597737   1.063114405   1.209901393   1.067529149   1.203566852   1.309272418       98   0.641895811   0.477254138   1.083803886   1.032127419   0.888917014   0.430828693   0.507554811   0.874254758   0.86299014       99   1.637553191   1.286170213   1.131808511   1.196170213   1.478723404   1.974574468   1.963829787   1.045696371   0.893026791       100   1   1   1.739965096   1.555376561   1.728755538   1.805544368   2.132635253   1   1       101   1   1   0.638500204   0.721097677   0.638500204   0.638500204   0.638500204   1   1       102   2.369311432   2.217302257   1.495113077   1.149104659   1.295141614   2.158165085   2.175215809   1.011974181   0.871464654       103   1.35355286   1.200828507   1   1   1   1.307765957   1.17   1.089723368   0.967908275       104   0.937735085   0.855936462   1.248323618   1.108248812   0.890015837   0.965191899   0.965242444   0.997082821   0.736820781       105   1.270029838   1.106531108   1.974352083   0.951698983   0.960376272   0.477289307   0.598003456   1.106402722   0.970770182       106   1.831595745   1.479574468   1.033810376   1.205008945   0.996690519   0.84078712   0.883542039   0.922787376   0.907248335       107   1.333922285   1.052040683   1.115858587   0.944515691   0.670052375   0.689938249   0.558380572   1.179071469   1.226367997       108   0.799168516   0.804091106   1   1   1   1   1   0.794425986   0.855682075       109   1   1.11393617   0.983675178   0.983675178   1.326182503   1.109564671   0.983675178   0.88612368   0.88612368       110   1.206452194   1.449400739   0.836294516   0.902960311   1.001633005   0.963917122   0.796318554   0.871224897   1.040165568       111   2.339048832   2.453352175   1.080214356   1.199357947   1.557072102   1.052760025   1.173599685   0.840948461   0.722667997       112   0.378650832   0.324518401   1   1   1   1   1   1.454978038   1.508756617       113   0.805106642   0.728253711   1.476328079   1.002656159   0.63502627   0.305283129   0.556859311   0.828264006   0.953744891       114   0.412230029   0.447650273   1.418761259   0.862304079   0.720938063   0.750826333   0.644051247   1.118098608   1.379272291       115   0.640152547   0.640152547   1.588451792   0.970335063   0.667772817   0.556614778   0.552190177   1.193320022   1.204029769       116   1.320476264   1.501204146   1.378149389   1.104858556   0.960121405   1.096116437   1.359657346   1.093302316   1.005697964       117   0.434842948   0.434842948   1.217395015   1.119665415   1.163280983   0.941532946   0.962103107   1   1       118   1   1   1   1   1   1   1   1   1       119   0.693666202   1.026692335   0.49564269   0.555458132   0.65225992   0.577565467   0.624512142   0.922121241   0.954443559       120   1.472345405   1.226071693   0.895900125   0.949750041   0.994199315   0.767008097   0.926615226   0.853587371   0.904278715       121   1   1   1   1   1   1   1   1   1       122   1.119680851   1.157340426   1   1   1   1   1   0.908104323   0.822685104       123   0.601369074   0.601369074   0.605175139   0.878523909   0.743411622   0.790642114   0.732862866   1   1.197765957       124   1   1   1.820957447   1.196170213   1   1   1   1   1       125   1   1.096382979   0.948575567   0.756478352   0.781345566   1.623531305   0.982858522   1   1       126   0.820198182   0.942804333   0.715699711   0.715699711   0.943962235   0.718212273   0.74120603   0.807369371   0.983554229       127   0.607094312   0.680024049   1.441950976   1.080838377   0.604353751   0.445069299   0.514077089   1.061354489   1.25245389       128   1.396382979   1.052446809   1.196170213   1.245106383   1.278191489   1.817978723   0.947479912   0.788093499       129   0.963806008   0.963806008   1   1   1   1.003510638   1   1   1       130   1.236588417   1.379203768   1   1   1   1   1   0.951117917   1.039816233       131   0.586528343   0.738943551   1.130290134   0.810065617   0.756762924   0.876115477   0.755930195   1.123079597   1.418534932       132   0.871188133   0.762537529   1.119334065   0.988280278   0.888218075   0.796084888   0.738569338   1.040234239   1.045128397       133   0.370794052   0.400023668   1.008510638   1   1.200425532   1   1   1   1.063723404       134   1.50235647   2.087189374   0.214881701   0.473311236   0.792341982   0.614904561   0.686341296   1.095309576   1.056322099       135   1.157446809   1   1.854477412   2.269099171   3.119553595   3.369326383   4.406789628   1.460618146   1.413160518       136   1   1.226382979   1   1.338829787   1.406489362   1.439680851   1.09606383   0.835271558   0.858097241       137   0.580555125   0.489843387   0.965290614   0.965290614   0.965290614   0.965290614   0.965290614   0.969272015   1.193235719       138   2.087226091   2.457363683   0.515803336   0.883834504   0.78500878   0.996268657   0.819743196   0.998329828   0.89533589       139   1.671742291   1.205830591   1.769357411   1.242167001   1.066934198   1.383906982   1.742707208   0.886316324   0.971287129       140   0.415125535   0.521245649   0.422180759   0.414201632   0.29149601   0.266284397   0.455068111   1.311887823   1.506495515       141   0.508703961   0.456820502   2.247943284   1.155135156   2.1235167   0.698563142   0.4427342   1   1       142   0.874423859   1.050655219   0.810258757   1.374240785   0.999167984   1.221066644   1.108037274   1.063616121   1.008906702       143   1.650107797   1.893550126   0.602525479   0.823729248   0.8298827   0.955002884   0.825139414   0.940375736   0.896274479       144   1.204081633   1.524430926   1   1.100531915   2.055744681   2.017553191   1.77787234   0.95710898   0.992576554       145   1   1   0.863680789   0.750520546   0.544341988   0.480771682   0.461479624   1   1       146   0.57766974   0.721005868   1.080999188   1.109063035   0.911750383   0.949373253   0.891460005   0.932191032   1.209705513       147   1   1   2.052066815   1.360978962   0.994079712   0.852309969   0.499312824   1   1       148   1   1   1   1   1   1   1   1   1       149   0.459187449   0.54771948   0.782238564   0.774487396   1.01318361   1.022441949   0.764202193   1.267950324   1.444896681       150   1   1   0.728254848   0.588144044   0.54598338   0.71933518   0.547257618   1   1       151   1   1   1   1   1   1   1   1.007446809   1       152   0.735484476   0.82589188   0.916485841   0.921232505   0.562493219   0.694314853   0.645546273   1.04601725   1.22587519       153   1   1   1   1.224787234   1.847659574   1.541489362   1.670425532   1   1       154   0.33286119   0.33286119   0.860537096   0.675921711   0.67935063   0.968472159   0.829555454   1.832821745   1.48836692       155   0.872938846   0.818767022   0.747930186   0.738811815   0.785186843   0.640803312   0.660774222   0.909454293   1.335331943       156   1.562608647   1.597207424   0.609360819   0.609360819   0.609360819   0.895047323   0.748282121   0.909980172   0.836351619       157   0.99030303   1.293535354   0.570422963   0.998482918   0.981795012   1.21609321   0.937435524   0.847729984   0.984001123       158   0.362416767   0.369625425   1.218879436   1.058427788   1.005890523   0.843764726   0.736954042   1.22902423   1.814486369       159   0.78424829   0.914483564   1.36195584   1.195526901   1.058138871   1.265247903   1.330689793   0.973948945   1.053846601       160   0.973226072   1.327887226   1.096179734   0.989532563   1.47734763   0.906883907   0.990669823   0.944122305   0.885279865       161   0.618817141   0.590091685   0.697972338   1.062757102   0.853480387   1.081835261   1.331130762   1.123546073   0.908836858       162   1   1.157340426   1   1   1   1.425106383   1   0.942900798   0.919472582       163   1.631364036   1.851088024   0.562022224   0.746355111   0.653164158   0.592481677   0.65852313   0.983174731   0.877379042       164   1.204148936   1.148723404   1   1   1   1   1   1   1       165   1.912996599   1.604628017   1   1.253404255   1.805638298   2.778617021   2.328085106   0.930108303   1.012490975       166   0.812607368   0.939595097   1   1   1   1   1   1.099661175   1.669996495       167   0.532200794   0.581689266   0.461077623   0.429089161   0.453348619   0.671424873   0.627306682   0.869839259   1.046277029       168   1   1   3.273465067   1.616737238   1.144024935   1.154904728   0.863502705   1   1       169   0.390472833   0.421572732   1.184377709   0.876133697   0.712521934   0.569390711   0.524285956   1.100338219   2.201754816       170   1.73331798   1.961022511   1.406904358   1.262900653   1.306014303   1.242835829   1.038431857   1.174746855   0.984657871       171   1.891037216   1.852851795   1.095762637   1.115690977   1.224926712   1.749637263   1.641052974   0.897061304   1.036978306       172   1   1   0.988002181   1.942192329   3.726504272   2.656153427   2.84548264   1   1       173   0.930305616   1.180240976   0.520525452   0.573092797   0.888008698   0.92710691   1.068521724   1.552102416   0.991185155       174   1.482873851   1.449271326   0.626404656   0.801878638   0.81663113   0.740275457   0.875583473   0.833777228   0.702606297       175   1   1   2.162234043   1.36712766   1.215425532   1   1.035638298   1   1       176   1.055071821   1.434529422   1   1   1   1   1   0.779672968   0.739112917       177   1.415241729   1.794082249   0.419926014   0.860410003   0.602269662   0.57047898   0.587453277   0.94100039   0.876434779       178   1.719832203   2.015173152   0.735483302   1.111133139   1.119129439   1.274121068   1.06632743   0.824712815   0.940955895       179   0.77963009   0.77963009   1   1   1   1   1   1   1       180   0.800561555   0.494470842   0.84078712   0.957602862   1.231216458   0.84078712   1.174776386   1   1       181   0.696977847   0.995293643   0.987179487   0.838703182   0.859846959   1.136931132   0.93381662   1.177926704   1.87767916       182   1   1   1   1   1   1   1   0.676440102   0.918185838       183   0.575391986   0.643031359   1   1   1   1   1   1   1       184   2.109684578   2.406007291   1.565092565   1.104346104   1.089199089   1.175626176   1.209088209   0.997502498   0.949959132       185   0.667705857   0.644363041   1.258993202   0.859121808   0.62340621   0.715542899   0.45252618   1.507952345   1.323669229       186   1   1   1   1   1   1   1   1   1       187   1.142346448   0.982086386   1.049162615   0.840163618   1.217874508   1.670448406   1.328548275   0.976899827   1.117659758       188   0.686954063   0.876139006   0.63211454   0.882400683   0.789648929   0.608141011   1.063325911   0.958494852   0.791308298       189   1   1   1   1   1   1.081914894   1   1   1       190   1   1   0.556658079   1.306499816   2.059919028   1.636555024   1.383496503   1   1       191   0.733517631   0.606769953   0.990935067   1.052714553   1.009064933   1.092521431   1.154941374   1.157773944   0.915577889       192   1   1   2.296382979   1.167553191   1   1.097340426   1.020319149   1   1       193   1   1   1   1   1   1   1   1   1       194   1.477340426   1.131276596   1   1   1   1   1   1   1       195   0.663385301   0.7365256121   1   1   1.931276596   1.497978723   1.697340426   1.117401906   1.129771669       196   2.214255319   1.832234043   1.257325241   1.2047928   1.789870239   2.097111762   2.137714525   0.903664112   0.970442398       197   1   1   1   1   1   1   1   1   1       198   1.138617021   1   1.267663719   1.365944549   1.036768359   0.533936202   0.67196661   1   1       199   1.523005242   1.904251602   0.62401015   0.693266833   0.754079713   0.900205626   0.753117207   0.947282213   1.003397234       200   1   1   1.081228831   0.863509418   0.628439004   0.558559629   0.603838612   1   1       201   1   1   2.08610977   0.919362627   0.756478352   0.756478352   0.756478352   1   1.130957447       202   0.195544262   0.175626909   1.500708737   1.081344144   0.675738504   1.069701952   1.225283967   1.238422634   1.674594122       203   0.949813712   1.002119448   1.014027234   1.010242107   0.852942555   0.744779338   0.669803361   0.773818859   0.801955339       204   1   1   0.767409584   0.767409584   0.989550167   1.205241244   0.841129888   0.986151909   0.986151909       205   0.341399177   0.336076818   0.980243232   1.1368063   1.307953963   1.15423326   1.163459298   0.799787975   1.14011308       206   1.278085106   1.191914894   1.024542152   1.441981167   1.863794765   2.16675317   1.940016312   0.949314079   0.979783394       207   0.236429103   0.414726103   0.680675422   1.073889931   1.059933292   1.276057953   1.088805503   1.102478464   0.943526872       208   1.973789125   1.653631917   1.675467207   1.360146333   2.794032087   2.900652327   2.315100494   0.832501387   0.947981434       209   1.014518954   0.895147167   0.683064298   1.214627108   1.992785643   1.369780864   1.638470556   0.914200554   1.225179192       210   0.753325854   0.753325854   1   1   1   1   1   1.172264616   1.028600613       211   1.12339396   1.199315869   1   1   1   1   1   0.889892367   1.199678337       212   1.312521266   1.509186798   0.557173245   0.919309856   0.71434649   0.633230915   0.724225951   1.088323554   0.786088592       213   0.960685392   1.134896828   0.653917373   0.711332115   0.712067887   0.657167033   0.598293009   0.873035603   0.957915298       214   0.632981863   0.641667597   0.956840931   1.011044931   0.972814161   0.782691901   0.732300772   1.19964347   1.693517274       215   0.933174399   0.797909408   0.877598152   0.957138976   0.747316941   0.638500204   0.651473985   0.92553917   1.196658426       216   0.62675386   0.788253797   0.877346809   0.977732366   0.915036693   0.978608172   0.799037619   1.191302572   1.211132095       217   1.265402034   1.458600359   0.905880211   0.982644578   1.021967352   1.49778506   1.27653377   1   1       218   0.868403025   0.772731446   0.924675837   0.889693684   0.740201633   0.735240091   0.655812892   1.144349119   1.339430195       219   0.373219281   0.41047616   1.439359787   0.950733899   0.81592424   0.919176952   0.699682886   1.313626731   1.28709192       220   2.049893617   2.378085106   0.84078712   0.84078712   0.84078712   1.515026834   0.84078712   0.869263923   0.951494591       221   0.234759372   0.265577783   1.339801051   1.22425394   1.647904325   1.794322119   1.301732424   0.904570736   1.125580228       222   1   1   0.930600931   1.13978814   1.089199089   1.326205326   1.129294129   1.107135492   0.998247061       223   1.204684521   1.291259925   1.228749355   1.540518028   1.970251081   2.722779739   2.171988418   1.16250575   1.07656923       224   1   1   1   1   1   1   1   1   1       225   1   1   1   1   1   1   1   1   1       226   0.789568335   0.956907492   0.856285912   0.95530243   1.062479991   0.844344842   0.829353913   0.87124332   0.777659853       227   1.250528176   1.381554181   0.487956811   0.790801495   0.784468439   1.012406561   1.136004983   1.360228855   0.667381837       228   0.961520122   1.005102041   0.738350768   0.945184078   1.170764842   1.067518   1.203233256   0.958322468   0.879182964       229   1.185531915   1.061276596   1   1.291382979   1.847659574   2.160531915   2.417533191   0.952240408   0.840711922       230   1.866595745   1.832234043   1   1   1   1   1   0.923570319   0.728445075       231   0.791844157   0.863255498   0.821112684   0.378419422   0.535512734   0.915231861   1.017682831   1.018825055   0.95631404       232   1.024228595   1.003474754   1.276380814   1.096899225   0.990213178   1.288299419   1.262936047   1.169955525   0.927388012       233   1   1   1   1   1   1   1   0.884189508   0.950535487       234   0.899978884   1.077285845   1.253127744   1.126975417   1.331595698   1.5470259   1.545050483   0.938209954   0.60928497       235   1.900561555   1.922332613   0.957902973   1.219405321   1.532316119   2.043740219   2.102503912   1.022700038   0.799842504       236   0.607947836   0.550187401   0.852128126   0.81671159   1.039052216   0.718046762   0.944399173   1.067294423   0.837324458       237   0.920080289   0.772073   0.834029906   1.128138448   1.5338844   1.281477354   1.899817343   0.936843723   0.758157046       238   0.847601397   0.804690284   0.93067768   1.032684963   0.753752554   0.758193445   0.825295319   1.002511688   1.038495971       239   0.961976081   1.089934203   0.870610633   1.024608659   1.119235651   0.902482019   1.005076858   0.691436777   0.82793472       240   1   1   1   1   1   1   1   1   1       241   1.970046742   1.274348946   1   1   1   1.642978723   2.06893617   1.230242622   1.319274972       242   1.781871649   1.186265352   0.902636917   0.978814514   0.982946435   1.272481406   1.141461949   1.28873842   1.15740913       243   0.813078453   0.813078453   1.045567215   0.896430637   0.668388003   0.576055523   0.622407668   1   1.097340426       244   1.176008278   0.934998809   0.896438953   1.110125969   1.218507752   1.229360465   2.027252907   0.90438173   0.872632752       245   0.926216835   0.727936174   1.446170213   1.376595745   1.03287234   1.248510638   1.035638298   0.964633464   1.004141018       246   1.10096057   0.907906227   1   1   1   1   1.004893617   1.084680851   1       247   1.787719151   2.056549098   1.038625963   1.284487825   1.594555492   1.129612233   1.385124307   1.004798038   0.856250479       248   1.333384474   1.114682418   1.033297872   1.243829787   1.889574468   1.468829787   1.548404255   0.852924188   0.79032491       249   1.558861779   1.334097102   0.814464609   1.138884653   1.063121685   1.098435938   1.139071052   1.02845267   0.899574447       250   1.975155022   1.594454468   1.271580504   1.298454788   0.995183136   1.66060187   1.324709081   0.963759768   1.212740123       251   0.803195311   0.729476324   1.088252716   0.777517782   0.843217788   0.690082584   0.548784249   1.136889061   1.599732078       252   0.871366546   1.017661344   1.460820551   0.989281094   1.271946036   2.098133432   1.602199224   0.907248335   1.236174114       253   1.146200112   1.091389895   1.153640996   1.077855273   1.490564808   1.542270964   2.08862671   1.001475331   0.826265468       254   1.94684466   1.85973301   1.152952134   1.384992306   1.021037499   1.77533004   1.887341055   0.805760897   1.114750616       255   0.89118163   0.882155956   1   1.071808511   1.185425532   1.173510638   1.299255319   0.799244903   1.101283665       256   1.667059301   1.403432169   0.497034721   0.572927161   0.581755487   0.580727246   0.617484239   0.97975823   0.776012396       257   1.463897449   1.732901044   1.717886892   1.144454187   1.18643139   1.291977203   1.357737834   1.17912892   0.996062718       258   0.223332169   0.312579213   1.358159756   0.921119684   0.57429218   1.062701566   0.842239367   1.071370618   1.589720367       259   0.754010695   0.700625397   0.646565227   0.915585142   0.770026852   0.909543522   0.864175431   0.990314608   0.627880569       260   0.490012143   0.612537948   1.137029741   0.970739442   0.853408927   0.728967472   0.790851871   0.950043215   1.407490637       261   1   1   0.340460584   0.515545585   0.400469698   0.371656911   0.370955869   1   1       262   2.889815091   2.631486057   0.935771194   1.32141876   1.514893217   2.24528261   1.826841047   0.938081662   0.894495819       263   0.785265363   0.591081405   1.029144212   0.921233024   1.205733994   1.131666307   1.430135805   1.022490086   1.246921311       264   1.370690713   1.595816464   1.705106383   1.215319149   1.259893617   1.381276596   1.534787234   1.05628228   1.082154752       265   1.041224971   1.004806927   0.687687688   0.865700752   0.789696913   0.73972942   1.005293954   0.932566269   0.870084474       266   0.681356915   0.681356915   1   1   1   1   1   1   1.080531915       267   1   1   0.834580509   0.839070341   1.042609385   1.395457347   0.931684127   1   1       268   0.738085927   0.811833063   1   1   1   1   1   1   1.378723404       269   1.874264912   1.156230748   0.658060763   1.029576267   1.063492774   1.777126493   1.694706698   1.102332127   1.149348038       270   0.942544871   0.942544871   1.84393617   1   1   1   1   1   1       271   1.036003996   0.080946558   0.577963793   0.725960877   0.805100834   0.825467026   0.807755798   0.786921695   0.83901315       272   1.384526103   0.902818249   0.399616049   0.823612978   0.859589173   1.072528316   1.125897485   0.904483793   0.993681807       273   1.679063545   1.610345596   0.711770632   1.165172009   0.658920874   0.82926225   0.941766173   0.900181984   0.840650591       274   0.656669693   0.603324672   0.541104912   0.993275553   1.283926634   1.771291315   1.536561068   1.025125628   0.816766761       275   0.267973826   0.36703655   1.608805619   0.988357228   0.665562413   1.289777179   1.401792465   1.290240811   1.273034409       276   1.039539951   1.295567382   0.791784239   0.95864058   0.959763037   0.893101567   0.782523969   0.887794433   1.065024982       277   0.798369288   0.798369288   1.088357702   1.052992831   0.898699148   0.829080688   0.763624082   1.056153101   1.428149225       278   0.928608958   0.892814922   0.527003795   0.835155211   0.81134646   0.710694476   0.802815531   1   1.197765957       279   1.119680851   1.387553191   1   1   1   1   1   0.927141614   1.317543205       280   2.253426364   2.580363818   1.56980809   1.500820432   1.99522009   3.269387173   2.241706499   0.884051204   1.141978911       281   0.983016983   0.681634155   1   1   1   1   1   1.209195978   0.927208945       282   1.840125786   1.711383648   1   1.433191489   2.055744681   1.686276596   1.548404255   0.873075453   0.802592708       283   0.583487434   0.654502398   0.57013144   0.690176711   0.516269259   0.958175785   0.68393909   0.975506815   1.101109095       284   1.097865854   1.175391986   0.735524257   0.767057903   0.736697966   0.795774648   0.828090767   0.989006302   0.997820215       285   0.452363537   0.905184237   1   1   1   1   1   1   1.280531915       286   0.898667568   1.028483151   0.766758001   1.022795966   1.499392673   1.862969973   1.531877631   1.031686047   0.801356589       287   0.442389849   0.530723288   1.617511057   1.361044096   1.731905911   1.868884868   1.529386141   0.864257882   0.95940037       288   0.786Q55347   1.228320583   1   1   1   1   1   1.112351492   1.29498893       289   1.054987044   1.060564803   1.490766823   1.684976526   2.26486698   1.951799687   2.047339593   0.892422305   1.031244788       290   0.738425054   0.834504311   2.378682105   1.181309949   1.888415915   0.759662864   0.576252909   1   1       291   0.751661039   0.78286679   0.646225767   0.772996013   0.646225767   0.646225767   0.646225767   1.115762798   1.061632032       292   1.833996057   2.334948374   0.814410677   0.973541347   0.693155379   0.821787357   0.680963117   0.808554122   0.935129297       293   1.038166624   1.149651073   0.71748591   0.955232931   1.132410644   1.361810658   1.212456303   0.917858487   0.845878811       294   1.030693428   0.947937456   0.777345491   1.261049589   1.719225795   1.657106839   2.051979526   0.786103971   0.738023298       295   1   1   1.564574468   1   1   1   1.184574468   1   1.50787234       296   1   1   0.659745257   0.775640175   0.831564283   1.07861218   1.257463182   1   1.297021277       297   1   1   1.705106383   1   1   1   1   1   1.836595745       298   0.847927954   1.773539318   1   1   1   1   1   1.261653201   1.150670337       299   0.594965599   0.89122453   1.288324302   1.290100974   1.235794024   0.74638003   0.857984661   0.929071794   0.965068005       300       1   1   0.419221373   0.796122626   0.689534242   0.624596107   0.588659469   1   1       301   0.850134805   1.159111972   1.416666667   1.185324869   1.563106796   0.849103809   0.684889221   1.054783444   0.723909638       302   1.980319149   2.290319149   1   2.705106383   2.739893617   1.931489362   2.199148936   0.772203412   0.821037896       303   2.266663125   1.817803513   0.874272847   1.074341653   0.828642022   1.086069932   1.08137862   0.931518345   0.881553425       304   1   1   1   1   1   1.097340426   1.227978723   1   1       305   0.774141092   0.657752351   0.868643303   0.880948632   0.793397984   0.673720595   0.584791167   1.220011355   1.112243685       306   0.315068933   0.391104541   0.506165527   0.581336492   0.506165527   0.506165527   0.584782726   0.9943101   1.497403983       307   1.082411363   0.887172746   1.112366533   1.15558443   1.48985933   1.409185922   1.444890119   1.175604679   1.164502379       308   0.78333477   0.673633856   0.947111728   0.888988322   0.712022909   0.623920533   0.593494116   1   1.411276596       309   0.629003471   0.655452029   0.515366793   0.653000476   0.640357203   0.509321345   0.582971476   0.87410894   0.83583529       310   1.453295991   1.960790415   0.999150434   0.796043449   0.760665089   1.313429213   1.08252928   0.913580247   1.01449515       311   1   1   1.313496388   0.64156274   0.596440247   1.254247891   0.587056544   1   1       312   0.482185337   0.474594392   0.746039948   0.971633733   0.849402206   0.728346667   0.824367906   0.863247296   0.871408666       313   1   1   1.399354578   1.159453697   0.824410765   0.594421714   0.560998098   1   1       314   1   1   1   1   1   1   1   1   1       315   0.792106262   0.713472486   1.324242844   0.582160926   0.926640793   0.416349019   0.58347718   1.158498162   1.200857693       316   1   1   1   1   1   1   1   1   1       317   0.882651239   0.671380616   1   1   1   1   1   1   1.181170213       318   0.706076767   0.706076767   1   1   1   1   1   1   1       319   0.604165605   0.646178344   0.880580921   0.646527614   0.64133841   0.671327964   0.752266065   0.940996992   1.12875761       320   0.189530013   0.163060943   1.006789806   1.023034838   0.795407996   0.920196399   1.167566051   1.268970098   2.011456777       321   0.935695799   0.935695799   0.899729891   0.911949088   0.589362309   0.272574755   0.360989168   1.406355004   2.327027027       322   1   1   1.846919302   1.238367866   0.878044348   0.475236278   0.487186478   1   1       323   0.909266783   0.909266783   2.316515945   1.43944442   0.774176799   0.525896759   0.629786682   0.986151909   1.246537977       324   1.683611505   1.617004836   1.520592021   1.76137221   2.165424045   2.13753162   2.252585097   1.030649335   1.052181901       325   1.44206545   1.32468344   1.185825498   1.084369629   1.144474775   1.320341725   1.239156809   0.994642947   1.261232122       326   0.520250906   0.508300438   1.573032344   1.040475757   1.069846471   1.036045877   0.700467261   0.969422992   1.065800213       327   0.468477448   0.468477448   1   1   1   1   1   0.963454888   1.45779629       328   0.484884222   0.605266142   1.350114109   1.299704658   1.536582092   2.262384213   1.653309169   1.108662004   1.491515707       329   1   1   2.125213383   1.232843974   0.878200751   0.905001707   0.802321611   1   1       330   1.4264948   1.475966751   1.080462957   1.080116432   0.930903042   0.7546261   0.799916834   0.903714535   0.855155466       331   0.511926805   0.87964274   0.868600998   0.868600998   0.868600998   0.868600998   0.868600998   1   1       332   0.423156698   0.623909646   0.670614254   0.670614254   0.670614254   0.670614254   0.704715702   0.96129269   1.209251842       333   0.539114476   0.539114476   0.715699711   0.760164459   0.805238313   0.715699711   0.715699711   1   1.164468085       334   1.031990967   1.130033873   0.467057538   0.873298221   0.985789526   1.154476796   0.780184836   0.859546452   1.086503292       335   1   1   0.854390111   1.095255408   1.151881476   1.527176877   1.711688784   1   1.130957447       336   1.975420561   4.114859813   0.709495612   0.821359777   0.73403724   0.945922808   0.823500036   0.887794433   1.000927909       337   1.102425605   1.107122488   1.178784388   1.229367123   2.002303835   2.239192302   1.841814609   0.975056958   0.921531497       338   1.048432948   1.584898045   0.688343487   1.054886758   1.233611216   1.969918675   1.554172618   0.741739026   0.827655332       339   0.81340984   1.25119541   0.814769871   0.814769871   1.550836439   1.597122302   1.470312906   0.664783937   0.803976943       340   0.633331062   0.624669323   1.305114654   1.002119357   1.171058496   1.239159898   2.242061507   0.815678188   0.857057137       341   1.209220722   1.293337882   1   1   1   1   1   0.903752964   0.999793793       342   1.725508894   2.224170182   1.057862546   1.105585064   0.851118622   1.655882826   1.171334299   0.910475447   1.133798692       343   0.489218956   0.44078182   0.938520939   0.930600931   0.930600931   0.930600931   0.930600931   0.690719377   1.557351753       344   0.920521173   0.738532286   1.025565784   0.989950557   1.285886562   0.981629618   0.966274068   0.941332547   0.932134434       345   1.801206839   1.781075216   0.820273322   1.305840958   1.479963364   2.115540522   1.671941454   0.717002407   0.734058666       346   0.327937483   0.542038794   0.749633403   0.95060585   0.725476576   1.097244733   0.725476576   1   1.247553191       347   1.216566158   0.877350124   1.156382979   1.17712766   1.094574468   1   1.155319149   1.147409105   0.983191767       348   1.320326894   1.191758332   0.815347894   0.971716229   0.80586314   1.009556541   1.181251234   0.972111947   1.015435828       349   1.521504941   1.422606512   1.018662191   1.152794806   0.910749101   1.496824312   1.46798183   0.973177442   0.999541495       350   0.725814597   0.645352892   1.181685544   1.405068151   1.763409484   1.8   1.71906316   1.011935875   1.190111815       351   0.522677191   0.794211478   0.930600931   0.97950698   0.930600931   2.261063261   2.058608059   0.921703808   1.040106416       352   0.635373784   0.62209892   0.69340556   0.845470174   0.319666548   0.304907717   0.347789419   1   1       353   0.83605   0.75365   1   1   1   1   1   1.19   1       354   0.359324957   0.40166913   1.242113827   1.013719907   1.088458267   1.104470988   0.993676269   1.059146833   1.047019968       355   0.618289832   1.086248032   0.506617503   0.622875562   0.61078824   0.44334831   0.546127173   0.865266994   1.132655548       356   1   1   1.867021277   1.13893617   1   1   1   1   1       357   0.71142572   0.632468504   0.785095797   0.740482146   0.714753017   0.528711619   0.561532752   1.100013962   1.276725462       358   1.278085106   1.669255319   0.487956811   0.983232973   0.650695598   0.865137043   0.735568937   1   1       359   1   1   1   1   1.094574468   1.859574468   1.299255319   1   1       360   1.248339248   1.357630358   0.767379176   0.866670846   0.905158904   1.095718674   0.757224347   0.934937475   0.916684502       361   1.889101396   1.720431087   0.828889719   1.051306945   1.333980583   1.445170525   1.186880757   0.9731415   0.935971495       362   1   1   1   1   1   1   1   0.784940283   0.803369453       363   3.235425532   2.640425532   1   1   1   1   1   1   1       364   1.620046083   1.14751861   0.52660431   0.816151026   0.558844691   0.57100764   0.71244047   1.013540254   0.738888765       365   1.530957447   1.65287234   0.955645161   1.205745968   1.277520161   1.748387097   1.570060484   1.075   1.181170213       366   1.654282978   1.611247947   0.507054598   1.04488221   0.732470392   1.170657147   0.92819274   1   1       367   1.54474764   2.114286534   1   1   1   1   1   0.904574578   0.806360588       368   1.425081687   2.076915098   1   1   1   1   1   1   1       369   0.874624604   1.016612105   1.281010444   1.643669291   1.927149251   1.215774039   1.406492772   0.992527534   0.764896138       370   0.582719279   0.754433394   1.13425386   0.848810607   1.044696416   1.314406643   1.234552952   1.18336969   1.258520353       371   0.356069578   0.356920799   0.65172556   0.944452083   1.001993675   0.646225767   0.929740135   1.251101675   1.278343081       372   0.44009551   0.44009551   1.33202235   1.179613757   1.012666811   0.5471954   0.60662363   0.985749572   1.260307809       373   1.26893617   1.235   0.388333471   0.538254978   0.706601669   0.67731141   0.752375444   0.735278434   0.725375181       374   1.160723574   1.689475813   0.561686919   0.954777222   1.066857279   1.929473433   1.82749583   1.107846801   0.525875759       375   0.806290717   0.406168567   2.234498475   1.313816297   1.412577645   1.342044327   1.322600801   0.951581983   1.243091017       376   1.003094911   0.821870702   1.353154164   1.051608955   0.865571931   1.035697894   1.054209802   1.057813444   1.300371042       377   0.811071812   0.68139729   1.048555785   0.957968591   1.160289827   1.042195338   1.233959542   1.021617489   1.102874222       378   1   1   1   1   1   1   1   1   1       379   1   1   1   1   1   1   1   1   1       380   1.018143301   0.91440872   0.714153636   0.852313382   0.761144833   0.587932629   0.595369217   0.984542947   0.955531247       381   1.708297872   2.234468085   0.502406761   0.535384898   0.450413375   0.392761345   0.172698879   1   1       382   1.342021277   1   1   1   1   1   1   1.043621943   0.836351619       383   0.970129508   0.681451051   1.372391936   1.271590809   2.505238137   2.149837134   3.240602166   0.877707995   0.892950392       384   0.360888773   0.459459459   0.694944756   0.659527774   0.371071086   0.344836285   0.399298724   1   1       385   1.526726313   2.005849966   0.718467988   1.022027997   0.626518866   0.712410289   0764780075   0.889165668   0.836444472       386   1.568973587   1.829488465   0.440755849   0.446898298   0.683406011   0.576405495   0.572654382   0.901565747   1.060663402       387   1.391678653   1.565592001   0.977197267   1.138591001   1.232129909   0.864423921   0.909227951   1.034619901   0.796563121       388   1.198756492   1.372837432   1.139182211   1.234683909   1.420198167   2.348234637   3.199516212   0.88612368   0.88612368       389   0.761941096   0.71722875   0.821721036   0.630957175   0.700295342   0.630957175   0.634044838   1.042676128   0.952863659       390   1.277848435   1.153674349   1.255764179   1.154416772   1.035947077   1.276948147   0.98217239   1.036976822   0.917667167       391   1   1   1.709526136   0.962432829   0.592134831   1.044357596   0.459208598   1   1       392   0.860349604   1.301790471   0.664880549   0.902737209   0.855459909   0.544781894   0.633823387   0.914661765   0.90344307       393   0.698198951   0.734420423   0.45538223   0.70400155   1.041711075   1.490359461   1.601346769   0.981990521   1.206635071       394   0.601369074   0.601369074   1.581543265   1.071268813   0.93523135   0.850682634   0.713084199   1.130848694   2.234082776       395   1   1   1   1   1.362765957   1.845106383   2.042765957   1   1       396   1   1   1   1   1   1   1   1   1       397   0.987666208   0.817606602   0.942013669   0.961671246   0.931515536   1.581131544   1.490734869   0.895127694   1.016120268       398   0.646136926   0.697071762   0.908102518   0.847005701   0.640356188   0.959815347   0.618359316   1.230757659   1.00742115       399   1.219066996   0.843888432   0.97140624   1.33852233   1.510823075   1.187172974   1.549186912   0.830499064   0.725422056       400   1.954148936   1.815957447   0.666051979   0.913156227   0.947617127   0.724370426   1.020803319   0.937188435   0.937188435       401   1   1   1.358990944   1.504435409   2.033727592   1.275827019   1.474311588   1   1       402   1   1   1   1   1   1   1   1   1       403   1   1   1   1   1   1   1   1   1       404   1.849148936   1.767234043   0.9303044   1.103714587   1.141011151   1.279347498   1.346820374   1.021234799   0.879326473       405   0.690563003   0.755576408   0.7744892   1.190134267   1.311675423   1.345300642   1.438937536   1.211726861   1.167495248       406   0.993776229   0.856177538   1   1.081382979   1.805638298   1.292978723   1.493723404   1.038132807   0.750558843       407   1   1   0.839550496   0.813922942   0.985113835   0.773759486   0.628166959   1   1       408   1   1   1.135531379   1.702733183   2.557648932   3.180443147   2.278227411   1   1       409   0.936504134   1.013912492   0.719315219   0.904104673   0.861031463   0.737053937   0.698955448   0.878072761   0.656750474       410   1.136636391   1.462651068   0.91419624   1.101920011   1.807387888   1.307955967   1.246269298   1   1       411   1.350526859   1.294156658   1.057361983   1.097673829   0.957850035   1.868606199   1.866070863   1.137602086   1.164985245       412   1   1   1   1   1   1   1   1   1       413   1.00393617   1   1   1   1   1   1   1   1       414   1.596098575   1.44306855   0.882254389   1.135471116   1.693874816   1.566479024   1.409864629   0.904023739   0.933341246       415   0.715770213   0.667921011   1.437536384   1.272790779   0.949528467   0.867330306   1.174991268   1.3219676   1.059596295       416   2.041276596   1.864680851   1.187664338   1.190443994   0.941702351   0.933889265   0.927503568   0.966855069   0.807480287       417   2.185061528   2.103787084   1   1   1   1   1   1.044953747   0.601392787       418   2.517463449   2.999187747   0.644690782   1.238817581   1.125891352   1.56599248   1.426422922   0.95957385   0.854510531       419   1.103287874   1.184480389   0.979133065   1.042842742   1.630947581   1.680040323   1.582862903   0.911687259   0.864762676                   AD   AE   AF   AG   AH   AI   AJ   AK   AL       1   MG.IMPnCMS   MG.JRF   MG.JRFnCMS   PA.CMS   PA.IMP   PA.IMPnCMS   PA.JRF   PA.JRFnCMS   max               2   1.042724783   1.061480176   0.934393638   2.061728395   2.220716652   1.612165011   1.918598816   1.485596708   2.220716652       3   1   1   1   2.774439063   2.988138776   1.408520312   0.975882179   2.397746368   2.988138776       4   1   1.121808511   1.052021277   1.266808511   1.183617021   1.006595745   1.366276596   1.421914894   1.751382979       5   1   1   1   1.104787234   1.082659574   1.242021277   1.145531915   1.248085106   1.500295975       6   0.966428192   0.863150771   0.873471262   1.240099212   1.1604023   1.21717681   1.268282046   1.123906348   1.765429848       7   1   1   1   1.210001574   1.324867503   0.501757884   0.493257071   0.785433174   1.795       8   0.673885857   0.800875398   0.831798545   1.017539221   1.153181738   1.060197426   1.053851578   0.972677596   2.296542996       9   0.933641128   0.841495821   0.998708451   1.086904413   0.831903202   1.169639556   1.136323648   1.370006758   3.001736993       10   1.167537815   1.009579075   1.438226698   0.818387935   1.001350181   1.381846436   1.1150456   1.334004178   1.808195539       11   0.770591549   0.786760563   0.939267606   1.549893617   1.153404255   1.301170213   1.449680851   1.201914894   1.843345703       12   1.135766423   0.806443494   0.891970803   1.21049036   0.98618491   1.1734477   1.211325338   1.066039168   2.075408433       13   1   1   1   1   1   1   1   1   2.517521713       14   1.032547251   0.935533604   1.089076686   1   1.143297872   1.075957447   1   1.34   1.955319149       15   0.723129081   0.778566047   0.853748117   0.947388342   1.044158466   1.15640508   0.969341408   1.036882833   2.702102922       16   1   1   1   1   1   1   1   1   1.888025331       17   1   1   1   1.228191489   1   1   1   1   1.843919659       18   0.986876155   0.99103512   0.928650647   0.956442556   0.993777508   0.901148379   0.807305104   0.861739262   2.120359367       19   1.469944382   1.112740732   1.056884983   1.127041831   1.110166785   1.19478765   1.079388863   0.95792292   2.387178962       20   1   1   1   1   1   1   1   1   1.185009336       21   0.790824241   1.004247094   0.929503319   1.464515247   1.050458088   1.182606318   1.149842746   1.01422125   2.017531306       22   0.82620436   1.346925997   1.129573827   0.669932691   0.93550311   0.678509557   0.971542984   0.855130499   1.729840999       23   0.903297754   1.09160427   0.837661303   1.394516191   1.049778335   1.334329221   1.356929453   1.329124904   1.654850234       24   0.695457853   0.916224925   0.900010394   0.822128702   0.851054762   0.956903899   0.705092691   0.801832517   1.669270198       25   0.79604143   1.1928916   1.051787741   1.294877092   0.952558011   1.164428837   1.235144254   1.265819734   3.206198347       26   1.166926677   1.374310972   1.366614665   1   1   1.113404255   1   1.015531915   1.994787234       27   0.950819034   1.062215478   1.145363994   1.311621461   1.118511186   1.224747575   1.125678084   1.248584439   2.083623039       28   1   1   1   1.104787234   1.072553191   1   1.00787234   1   1.781395534       29   0.927252267   0.922453167   0.948169723   0.823264104   0.801658604   0.929400211   0.804604808   0.810097116   2.428296568       30   1   1   1   1   1   1   1   1   4.503857155       31   1.227146814   1.079160452   1.066375453   0.971569005   1.07845027   0.939909406   0.907382421   1.100086739   1.509972607       32   1   1   1   1   1   1   1   1   1.195268404       33   1.514607185   1.346624556   1.062179234   0.646814692   0.75982569   0.53529778   1.074891056   0.959037145   1.997275957       34   0.866779457   1.017862128   0.84455649   0.757427743   0.928413731   0.904359244   0.859886582   0.767961501   2.520246578       35   0.719737331   0.866807087   1.044149837   0.924415464   0.925495794   1.102052628   0.917817733   0.850065591   2.065186463       36   1.364932212   1.044531376   1.598628155   1.202901317   1.665012407   1.021950754   0.916714386   2.177642044   2.177642044       37   0.937174211   1.120667581   0.940329218   0.595014251   0.787850428   0.625515804   0.893350917   0.800740205   1.338085106       38   0.570032669   1.010948583   0.855843659   0.866031294   1.174891307   1.129399916   1.187467761   1.292230601   1.715795832       39   1   1   1   1   1   1   1   1   1.98       40   0.859546452   1.01892831   1.163222385   1.09192667   1.161290323   0.909130971   1.114577825   1.297109113   1.679574468       41   0.716081359   0.813133237   0.716081359   1.051601988   1.138257375   1.404991012   1.00058158   1.008036375   2.152956094       42   0.612832592   0.88544224   0.863346825   0.902549722   0.97826087   1.073803191   1.095137604   1.065188483   1.572115385       43   0.68911809   0.905898714   0.920825125   0.900278229   0.973823325   1.094551356   0.754300951   0.856178994   2.063944927       44   0.709172555   0.866968236   0.866538995   0.892290483   0.89231992   1.050866916   0.871213682   0.863089105   1.958297872       45   1   1   1   1   1   1   1   1   2.082566083       46   0.747873697   1.052621316   0.961554039   1.280618973   0.939772301   1.051601273   1.080541541   0.93297279   2.959946506       47   1.260273973   1.100329782   0.838597159   1.592978723   1.183617021   1.327978723   1.820531915   1.358297872   1.820531915       48   2.033297872   1.048723404   1.02393617   1.570623703   1.30236236   0.929129188   1.682020362   1.454680241   2.033297872       49   0.986552567   0.984413203   1.325539935   1.571228606   1.718012343   1.146083858   1.252274607   2.41025641   2.93712766       50   1.302117427   1.088972013   0.971945762   1.036868268   0.916045291   0.808386265   1 .048099052   0.962625426   2.186170213       51   0.502692559   1.090323107   0.936398499   0.865859103   1.106788893   1.096907646   0.939224382   1.184440013   1.533123028       52   1   1   1   1   1   1   1   1   1.177917648       53   1.015685107   1.372211054   1.134018316   1.610238028   1.636434176   0.978022338   0.831555594   2.078402658   3.54637032       54   1   1   1   1   1   1   1   1   1.91976154       55   0.832413808   1.03626491   0.979981246   0.838172428   0.886653982   1.126467172   0.959697546   1.21982258   2.205435632       56   0.888135908   0.943093205   0.9506127   1   1   1.065319149   1   1   1.897178466       57   0.817033181   0.90423699   0.876910536   1.147759623   0.875239393   1.17717697   0.895201781   0.79459618   2.376071691       58   0.73686493   0.6006124   0.912410965   0.987289139   0.733456644   0.989064812   1.171663214   1.219754365   1.922027202       59   1   1   1   1   1   1   1   1   2.118660204       60   0.892158338   1.1410295   1.119807345   0.912001571   1.063445296   1.205526092   1.220454397   1.468670202   1.946388211       61   0.667727597   0.932283378   0.901607858   0.971050455   1.200419927   1.193612012   1.07660495   1.228478717   1.548198417       62   1   1   1   1   1   1   1   1   2.344487535       63   1.166210465   1.119942783   1.082451834   0.859078647   0.761527288   0.983731065   0.917244242   0.867337622   1.640632557       64   0.835638987   1.086601425   0.977729006   0.870923559   0.878318223   1.015009457   1.130813005   1.027312158   1.495203492       65   1.303154091   1.102452309   0.943818165   1.175614195   1.110267219   0.90969527   1.290969527   1.309390726   1.509356575       66   1.432184275   1.14683286   1.044986085   1.141747967   0.978857146   1.030791714   0.923486229   0.755454992   1.990445474       67   0.776800864   0.977093938   1.141215487   1   1.001382979   1.06   1   1.285   2.723510638       68   0.788877073   1.122202349   1.070068159   1.021036755   1.068164378   1.126220529   1.098806594   1.029821915   1.306231353       69   1   1   1   1   1   1   1   1   1.145851064       70   0.748288489   0.798439739   0.748288489   1.164525994   0.958205912   1.324057085   1.006422018   0.958205912   2.049187527       71   1   1   1   0.873358713   1.227488152   1.036593893   1.066350711   0.850672053   1.439610062       72   0.794388574   0.902053579   0.902138088   1.400319149   1.052234043   1.156276596   1.240425532   1.118297872   1.400319149       73   0.725836013   0.776913234   0.825154753   0.904878576   0.80024501   1.020429488   0.715968869   0.765078908   1.613131749       74   1   1   1   1   1   1   1   1   2.645851064       75   0.670402612   0.886996736   0.89390642   1.140970133   0.871578484   1.14918911   1.028693036   1.049167095   2.405626647       76   1.123702944   0.833277443   0.968880245   1.146331069   1.121773871   1.181861766   1.031428952   1.055400186   1.821919609       77   0.894958225   0.960357246   1.066954768   0.994198781   0.950985615   1.078079678   1.069614633   0.900846504   2.03255814       78   1   1   1   1   1   1   1   1   1.957809144       79   0.83977028   0.827494616   0.870782484   1.07212766   1.082659574   1.172340426   1.219361702   1.062340426   1.913829787       80   0.857724057   0.944575472   1.040035377   0.75   1.089388283   0.841901206   0.787406663   0.873420448   2.799558614       81   1   1   1   1   1   1   1   1   1.288229337       82   1   1   1   1   1   1   1   1   2.456382979       83   0.707405178   1.013320289   1.088801927   1.350898324   1.432500251   1.561678209   1.35792432   1.35862692   1.865868375       84   0.951263169   1.16231973   1.099314718   1.540947162   1.396029366   1.591665805   1.427825458   1.229603971   2.292097065       85   0.850266914   0.695021469   0.845740977   1.767919698   1.282807868   1.379682026   1.674885476   1.534997305   2.20384652       86   0.869662023   0.914722063   0.856348127   1.039223205   1.159170877   1.252007398   1.10206153   0.987955612   1.997200996       87   0.943522843   0.811617544   0.849224244   0.900411076   0.979135965   0.987163577   0.843403397   0.817265183   2.543371907       88   0.982939633   0.968775455   1.197619694   1.283341154   0.990239324   1.16015955   1.098967621   1.19042703   1.826611778       89   1   1   1   1.124361702   1   1   1.018510638   1   1.124361702       90   0.979971086   0.958918137   0.918830191   1.034680315   1.13261019   1.148155221   1.113245741   0.935604614   1.75005934       91   0.760484261   0.834468516   0.838494548   1.142975682   1.059636772   1.360443796   1.013490545   0.962847469   2.236809004       92   1.243132094   0.916515874   1.080769863   1   1   1   1   1   2.230032194       93   1.065417066   0.898421692   1.041765492   1.261537121   0.919325937   1.191407548   1.019694667   0.92233787   2.081177989       94   1   1.085319149   1.344361702   1.095371042   1.096878664   1.380479089   1.415321905   0.882237981   1.898723404       95   0.753975678   0.988347857   0.964715343   1.022453648   1.229743559   1.151366482   1.04550927   1.258036359   1.873970081       96   0.892771406   0.872670807   0.88913234   1.070765512   0.870168942   1.186093754   1.018797089   0.967960092   2.95755751       97   1.248675535   1.209789623   1.298972579   1   0.884422364   1   0.986143877   0.902838752   1.309272418       98   1.208123137   1.1231 94222   1.004442788   0.644906687   1.057503888   1.053479782   0.877741058   0.700835925   1.269471638       99   0.893026791   0.895591868   1.030590918   1   1   1   1   1   1.974574468       100   1   1   1   1   1   1   1   1   2.132635253       101   1   1   1   1   1   1   1   1   2.534574468       102   0.917178584   0.826623842   0.827528142   1.364487174   0.998893946   1.233589994   1.236142426   0.984685413   2.369311432       103   1.016804174   0.952074739   0.977008008   1.256778797   1.153312946   1.354943935   1.218858308   1.195922528   2.196905679       104   0.865546389   0.893391272   0.795301113   0.92116702   0.820162504   1.056500169   0.927257088   0.685190305   2.246112541       105   1.05015981   0.925250026   0.901020724   1.13492823   0.919279482   1.064396285   0.957894737   0.903349282   1.974352083       106   0.907248335   0.918154618   0.928964386   1   1   1   1   1   1.831595745       107   1.042344906   0.836124888   0.985080088   1.018801171   0.826134305   0.969885399   1.051646795   0.921804732   1.48176753       108   0.677042676   0.910519016   0.86548821   1.104715721   1.197273175   1.412608054   1.1l476562   1.294469042   2.004271418       109   0.88612368   0.904977376   0.907334087   1.075754752   1.278978755   1.092620201   1.132500932   1.085165859   1.608816121       110   1.201211099   0.860723593   0.936302315   0.815528634   0.785242291   0.682406388   0.647026432   0.735613987   2.52421181       111   0.685770313   0.82996577   0.868256212   1.271474506   1.422028524   1.432313432   1.008918068   1.16489463   2.453352175       112   1.601531704   1.113695236   1.16015317   1.564978541   1.786437768   1.481716738   0.604806867   1.100257511   2.019257841       113   0.782279394   0.874969945   0.759858139   1.402247913   1.41554271   1.386191394   1.074438022   0.998779705   2.027340426       114   1.682495375   1.155668798   0.979307994   0.993958814   0.782782619   0.78501745   0.925617895   0.79997755   1.682495375       115   1.484479942   1.244781267   1.253040479   1.10419914   1.400689623   0.935383307   1.075575079   1.085824949   1.588451792       116   1.101459091   0.934245204   0.968123795   1.337530769   0.958964727   1.179507975   1.164340291   0.939058921   2.309777246       117   1   1   1   0.542412002   0.542412002   0.542412002   0.542412002   0.542412002   2.092340426       118   1   1   1   1   1   1   1   1   1.92027355       119   0.96205318   0.924612767   0.935598439   0.826833369   1.453581349   0.932974557   1.054991856   1.229217949   1.480646388       120   0.820685901   0.863473054   0.826891671   1.009434548   1.057848675   1.095959282   1.015113897   0.949165167   2.08071487       121   1   1   1   1   1   1   1   1   2.117021277       122   0.822685104   0.952914406   0.896201645   1   1   1.177659574   1   1.043617021   2.137556404       123   1.053617021   1.007446809   1   0.898018167   0.949793559   0.864244426   0.938315442   0.904128819   1.402035969       124   1   1   1   1   1   1   1   1   1.820957447       125   1.210638298   1   1   1   1   1   1   1   1.623531305       126   0.844355007   0.790992991   0.929151343   1.077208918   1.370437655   0.984971098   1.125268373   1.138728324   2.016582507       127   1.542896025   1.433274459   1.214349828   1.160124906   0.945314044   0.708407447   0.91450255   0.918158821   1.542896025       128   0.723447772   0.894594595   0.929218408   1   1   1   1   1   1.817978723       129   1   1   1   1   1   1   1   1   1.867021277       130   0.677427259   1.018499234   0.916508423   0.881824464   1.088919604   0.954695539   1.046379482   1.117254089   1.857056954       131   2.146350365   1.38408064   1.070481404   1.206647618   1.31580634   0.594502452   1.761743264   1.508345128   2.278902452       132   1.175083201   1.014988892   1.047273315   0.932202346   0.897365385   0.840058024   1.331219966   1.2057565   1.455321987       133   1.210638298   1   1   0.802463639   0.991392104   0.836449985   0.799050163   0.721430692   1.210638298       134   0.753079312   1.217022064   1.036232033   1.184661819   1.297571683   1.44022957   1.974299172   2.255270499   2.255270499       135   1.492821535   1.03000997   1.133000997   0.957290673   0.850957658   0.930872532   0.826594261   0.892712996   4.406789628       136   0.703946554   0.988432513   0.812817023   1.301004923   1.16672287   1.083293991   1.244351521   1.209415256   1.439680851       137   1.123530625   0.969272015   1.082800577   0.757148611   0.757148611   0.757148611   0.757148611   0.775996778   1.262234043       138   0.855128047   0.973339107   0.915316096   0.814132175   0.734735879   0.878435856   0.791401784   0.831237137   2.457363683       139   1.036709825   0.950444275   0.941685707   1.270879685   1.155314051   1.244865651   1.096226254   0.993753209   1.964240147       140   1.181462006   1.107536859   1.506495515   1.216565526   1.208366146   0.822856349   0.994487423   1.836151387   3.119667503       141   1   1   1   0.721799892   0.825232281   0.927512862   1.151117254   0.834062812   3.404042553       142   1.128301047   1.055177021   0.950233801   1.307042323   1.110166785   0.879270959   1.130259635   0.936380831   1.374240785       143   0.801783156   0.988377647   0.979063843   1.023038811   0.926507019   1.101734104   1.011808423   1.138728324   1.893550126       144   1.043767399   1.026394474   0.991390865   0.996678406   0.844485353   0.832119417   0.944573395   0.95493837   2.055744681       145   1   1   1   1   1   1   1   1       146   1.002450683   0.995868271   1.107283185   0.954236965   1.151462291   0.879827741   0.779770503   0.893973671   2.066718898       147   1   1   1   1   1   1   1   1   2.052066815       148   1   1   1   1   1   1   1   1   3.736595745       149   2.046806512   1.150699228   1.117668545   1.104712874   1.103981949   0.520005085   1.092700289   1.262147647   2.046806512       150   1   1   1   1   1   1   1   1   1.303950299       151   1   1   1   1.059042553   1.082659574   1.118723404   1.15606383   1.211170213   1.861489362       152   1.014561136   0.954693049   1.187620497   1.317848882   1.200510794   1.207835389 1.186150732   1.3595798   2.979270021       153   1   1   1   1   1   1   1   1   1.847659574       154   1.799857645   2.259353174   2.289247742   0.550818999   1.161042922   0.38256126   0.606381887   0.601176074   2.289247742       155   1.149895725   0.975755996   0.994873132   0.82848581   0.980609907   0.82848581   0.82848581   0.82848581   2.108840902       156   0.81440846   0.993985459   0.896034369   0.885783327   1.031574708   1.107209021   1.137011679   1.21240435   1.953288113       157   1.194933689   0.979931233   1.021051154   1.269401104   1.220344757   0.994958098   1.205082783   1.193976971   1.39010101       158   2.075178076   1.341419458   1.361615699   0.911821355   0.851128843   0.603695712   0.929604796   0.888621783   2.075178076       159   1.051520614   0.905448625   1.095249171   1.089247685   0.480412065   0.483532267   0.46555396   0.46555396   1.36195584       160   0.871277698   0.8938169   0.901091836   1.089558991   1.154412054   1.246174122   1.035918014   0.877414532   1.678366138       161   1.019750755   1.125755287   1.122715257   0.94847098   1.184044102   0.907655502   1.100977741   1.07077179   1.331130762       162   1.263199593   0.98409824   1.052402241   1.180607352   0.844846978   0.977505476   1.092168354   0.87118925   1.425106383       163   0.66366659   0.989451961   0.862187572   0.84862608   1.023521701   0.912200214   0.974366443   1.162952714   1.851088024       164   1   1   1   1   1   1   1   1   1.930609818       165   1.091263538   0.942021661   1.086209386   1   1   1   1.00787234   1.127553191   2.778617021       166   0.882930249   0.759726604   1.354130155   1.479853879   1.481325991   1.136415681   1.167929775   2.353197754   3.348297872       167   1.002578485   0.957296662   0.92736512   0.736106162   1.153931002   0.802796586   0.968809924   0.796568752   1.329722501       168   1   1   1   1   1   1   1   1   3.273465067       169   1.413705211   1.429709328   1.477305034   0.694962399   0.640429266   0.663531125   0.78467934   0.61208296   2.201754816       170   1.141556715   1.053697453   1.130817224   1.358615093   1.215309711   1.534703814   1.498945091   1.594644306   1.961022511       171   1.114949897   0.91140052   1.005263335   1.281909227   1.18767313   1.175953548   1.13365651   1.266940124   1.906395265       172   1   1   1   1   1   1   1   1   3.726504272       173   1.499105584   1.295071014   1.214487381   1.05031298   1.127685262   1.453171135   1.491516082   1.162749498   1.955285435       174   0.71211833   0.872443641   0.838913726   0.901401274   0.948127389   1.011617834   1.127184713   1.29666242   1.482873851       175   1   1   1   1   1   1   1   1.192659574   2.162234043       176   0.749487963   0.7302488   0.669475875   0.864461223   0.94092324   1.448076032   0.974104245   1.230710643   2.209748609       177   0.726639231   1.020164701   0.960415653   1.252649365   1.165814945   1.300496903   1.374991169   1.172061559   1.794082249       178   0.940955895   0.931670734   0.934349146   1.154078693   1.008832837   1.126163148   0.934155212   1.03693732   2.015173152       179   1   1   1   0.43510099   0.378208739   0.378208739   0.378208739   0.378208739   1.40664693       180   1   1   1   1   1   1   1   1   1.879859611       181   1.333272958   1.347340458   1.481434523   1.017318125   1.166504382   1.45646126   1.230143274   1.230143274   1.892535022       182   0.536340507   0.851448619   0.721757914   1.133832899   1.219121054   1.250543006   1.126303215   1.164422242   1.319656757       183   1   1   1   1   1   1   1   1       184   0.953092362   0.850921805   0.851693761   1.070617263   0.798910963   0.93699749   0.91325988   0.97792147   2.406007291       185   1.413815365   1.294207407   1.206937027   0.819414185   0.829512052   1.067953107   0.98623647   0.934675105   2.560057887       186   1   1   1   1   1   1   1   1   1.884574468       187   1.612879349   1.066740686   1.258419689   0.973113965   0.695699924   0.529378221   0.638295176   0.605875644   1.981808511       188   0.674788007   1.061023622   1.107495457   1.151817575   1.467092835   0.925331552   1.182902395   1.324720924   1.467092835       189   1   1   1   1.019680851   1.052234043   1.225957447   1.177234043   1.23893617   1.498051682       190   1   1   1   0.552892751   0.953350103   0.674777041   0.77       191   1.126273157   1.082712068   0.911302783   0.887236563   0.809656725   0.744848535   0.92       192   1   1   1   1   1   1   1   1   2.296382979       193   1   1   1   1   1   1   1   1   1.634620715       194   1   1   1   1   1   1   1   1   3.616584047       195   1.232454001   1.109377078   1.254134338   0.766189971   0.992131393   0.959095735   0.857116093   0.929557235   1.931276596       196   0.842488248   0.783179857   0.726254105   1.163404255   1   1.017234043   1   1   2.214255319       197   1   1   1   1   1   1   1   1   1.27534418       198   1   1   1.154042553   1   1   1   1   1   1.365944549       199   0.933875273   0.984166464   0.977008008   0.905458897   0.727193225   0.900073644   0.879821412   0.858970818   1.904251602       200   1   1   1   1   1.183617021   1.06   1.145531915   1   1.229148936       201   1.210638298   1   1   1   1   1   1   1   2.08610977       202   1.293357501   1.479579772   1.397039445   0.775781179   1.130994832   0.564247076   0.691721314   0.613565622   1.935078418       203   0.803766982   0.842151413   0.892483419   0.930527494   1.334435377   1.10590993   0.755993458   0.94989649   2.511369531       204   0.986151909   0.986151909   0.986151909   1.082562555   1.291792425   1.141660987   1.173692922   1.276409308   1.537994087       205   0.902935534   1.091233783   0.767593013   0.665300285   0.774355438   0.447279368   0.701311471   0.640718181   1.346461923       206   0.786714801   1.050180505   1.002815884   1.182959375   1.13689829   1.288820797   1.220816448   1.304240387   2.16675317       207   1.674072867   1.229884121   1.283098792   1.158412205   1.133477979   0.728875525   0.858227697   0.917851163   1.674072867       208   1.145021455   0.846717459   1.026943398   1.443313253   1.348192771   1.453975904   1.355   1.504337349   2.900652327       209   1.198992265   1.017528919   1.14292811   0.918295705   1.358067181   1.015556167   1.045223018   1.16127478   1.992785643       210   0.899657514   1.210238539   1.074265457   0.83900347   1.196414803   0.853556284   1.05247687   0.942029684   2.014665812       211   1.110540641   0.922677224   1.076209328   1.50258008   1.282835167   1.235030669   1.096679973   0.980722422   2.492109403       212   1.170779773   1.119048685   0.941998477   1.228270021   1.10841464   1.192957258   1.100193155   1.067505324   1.509186798       213   1.121282074   0.917251176   0.9323448461   1.062446809   1.145531915   1   1.090319149   2.874680851       214   2.167156674   1.367066211   1.156327741   0.922464714   0.93847268   0.58700654   1.260321819   1.31828846   2.167156674       215   0.894595516   0.749722956   0.893103742   0.784047042   0.607909148   0.939985636   0.733638567   0.634213125   1.888290713       216   1.430966721   1.135106166   1.374719273   0.91911847   0.634313122   0.726143864   0.656700973   0.74134411   1.430966721       217   1.244468085   1.025851064   1   1.112292149   0.989265418   0.989265418   0.989265418   0.989265418   1.49778506       218   1.651391217   1.269752833   1.05854541   1.054727552   1.111038199   0.888239974   1.492556167   1.397718045   1.829529882       219   1.637050459   1.114994421   1.269617027   1.062721255   1.011929672   1.045757827   1.117710924   1.070163317   1.637050459       220   1.092960365   0.912870785   0.967548382   1.006595745   1   1   1.00787234   1   2.378085106       221   2.509890018   1.383389788   1.672604859   1.020651943   0.717261273   0.470269696   0.578838395   0.649253203   2.509890018       222   1.072798515   1.20169107   0.992472675   1.343652398   1.426694837   0.919897116   1.686110601   2.009277972   2.009277972       223   1.107138377   0.917450759   1.035461883   0.86774263   0.841747364   0.979728857   0.895717667   0.844846137   2.722779739       224   1   1   1   1   1   1   1   1   1.845106383       225   1   1   1   1   1   1   1   1   2.239912281       226   0.951369633   0.945977054   0.990306065   0.932288099   0.959843697   0.967700645   1.317953913   1.244256838   1.317953913       227   0.973985671   1.046575482   0.991839393   1.21715227   1.355495657   1.060689685   1.587066273   1.640504   1.952521799       228   0.774532812   0.994263364   0.900521512   0.963913656   1.125621774   1.203660253   1.329845143   1.309103707   1.557648637       229   0.840711922   0.973794831   0.9932921921   1   1   1   1   1.015531915   2.417553191       230   0.634663426   0.821146445   0.841806765   1.206191843   1.024784764   1.195408296   1.022610662   1.027828507   2.046184739       231   1.145672314   1.202345737   1.253084011   0.841045809   1.24887873   1.250432537 1.113577684   1.186207378   1.355688771       232   1.027115554   1.004828111   1.042631621   0.956337067   0.690651203   1.06561544   0.945025199   0.687008957   2.557722769       233   1.018333636   1.138319114   1.380286803   1   1   1   1   1.155531915   1.854810375       234   1.205180267   0.967458706   1.011798277   1.198192889   1.086623453   1.286846068   1.245334905   1.147384273   1.815583517       235   0.856301572   0.894066491   1.0054439   1.175247841   0.915005508   1.075045304   1.181075223   1.053014959   2.102503912       236   0.817598831   1.099764591   0.97783911   0.881539097   0.856071035   1.026018722   0.917813877   0.989881608   1.099764591       237   0.817574143   0.961404497   0.853224402   0.981244801   1.158662936   1.162292974   1.173107464   1.261173712   1.899817343       238   0.954068437   0.865239232   0.785014424   0.712737127   0.827812908   0.429087624   0.588427181   0.471979658   1.807218908       239   0.703200508   0.769640737   0.606356833   0.88003569   1.542538479   1.037474905   1.545750613   1.743386125   2.018731028       240   1   1   1   1   1.011595745   1   1   1   1.632234043       241   1.455164586   1.153873439   1.267345346   0.90375666   0.838807581   0.916840898   1.043704053   0.986915762   2.06893617       242   1.03824547   0.894006473   1.041593809   0.852879883   0.770939565   0.911009622   1.075156298   1.00869064   1.781871649       243   1.244468085   1.121808511   1.172340426   0.857335835   1.145440901   0.705440901   0.956472795   0.821688555   1.738084941       244   1.242294838   0.872632752   0.909858893   0.636542997   0.693033382   1.145886248   0.650830007   0.614749637   2.592553191       245   1.251669465   0.987614251   1.219473979   1.294803991   1.522054414   0.965759773   0.974756011   2.121912655   2.121912655       246   1   1   1   1   1.001382979   1.049255319   1   1   1.971589857       247   0.876155438   0.804729056   0.891109067   1.439560139   1.567647783   1.598380611   1.22659135   1.306165714   2.056549098       248   0.798483755   0.932924188   0.960794224   1   1.072553191   1.177659574   1   1.099680851   1.889574468       249   1.065886486   0.896976595   0.822529566   1.078098162   1.134853634   1.19906443   1.022475606   1.016628294   2.405414593       250   0.962249759   1.027351412   1.128693297   1.252803984   1.092804794   1.058387658   1.045167429   1.144268535   1.975155022       251   1.866066373   1.220552694   1.179411399   0.839070905   0.785469787   0.717513098   1.168529514   1.14195599   1.866066373       252   1.376315028   0.926551491   0.96293794   1.156914894   1   1   1   1   2.098133432       253   0.982539056   0.993686955   0.862482559   1.031549865   0.803303526   1.057306675   0.893470518   0.782762115   2.08862671       254   1.160570142   0.879960065   1.098776447   1.136534879   0.735996688   0.989443179   0.776940592   0.888408197   1.94684466       255   0.987666751   0.828844702   0.843342562   0.739096386   0.886987952   0.761144578   0.867951807   0.851144578   1.776382979       256   0.795516313   0.941672713   0.866657648   1.049613754   0.948525176   1.061873181   1.081163316   1.006838693   1.667059301       257   1.119442509   0.926202091   1.087595819   1.08330562   0.752710343   1.252909877   1.008014633   0.885700033   2.331692436       258   1.84064493   1.557723876   1.458479565   0.957369127   0.96507268   0.49043305   0.737514866   0.596320928   1.84064493       259   0.627880569   0.899405517   0.96640171   0.853819664   0.874060018   0.841801954   1.012579942   0.969147516   1.450548454       260   1.401382887   1.407951599   1.318121579   1.088138059   1.53577096   1.387926474   1.338799259   1.217865644   1.638737098       261   1   1   1   1   1   1   1   1   1.339042553       262   0.796473838   0.964671906   1.117196502   1.449473451   1.147811145   1.471121178   1.286939769   1.63522995   2.889815091       263   1.334690044   0.975787936   0.991129201   0.586637012   0.505353908   0.485818449   0.4361085   0.457478275   1.518343195       264   1.207221123   1.142057248   1.096876961   1.263687322   0.976349535   1.074867542   1.098825155   0.920909161   2.093297872       265   0.943635304   0.913741625   0.909736382   0.903934035   0.96830916   1.083316776   0.991919995   0.766507716   2.121435958       266   1.159148936   1   1   1   1   1   1   1   2.042978723       267   1   1   1   1   1   1   1   1   1.847456109       268   1.017765957   1   1   0.950356189   0.697536361   0.697536361   0.697536361   0.697536361   1.378723404       269   1.148400253   1.006146246   1.098426101   1.072358253   1.013300252   1.037338323   1.097535183   0.976978768   1.874264912       270   1.017765957   1   1   1   1   1   1   1   1.84393617       271   0.699567445   0.89468517   0.927066188   0.777698637   1.081814202   1.072191184   0.90016397   0.947789377   1.693486302       272   0.901351244   0.951657862   0.869627545   0.941124955   1.196847259   0.984156682   1.095776442   1.107360376   1.64067324       273   0.754026388   0.919563239   0.836055505   1.034670616   0.865488337   1.006290163   0.957830098   0.859456302   3.405015674       274   1.317195735   1.190433877   0.855650202   1.181199852   1.28707461   1.142073227   1.148436779   1.065572259   1.771291315       275   1.143878484   1.535289801   1.443344438   0.984009633   1.210015451   0.671815522   0.79438244   0.874019214   1.899023036       276   1.068736617   0.862098501   0.925910064   0.888636793   1.06957837   1.027509926   0.914539611   1.026848175   2.613085106       277   1.228246124   1.422432171   1.335319767   0.646052277   0.647130154   0.625202102   0.656628941   0.755557801   1.823438618       278   1.053617021   1   1   0.868208092   0.863904945   0.723956326   0.755234425   0.731213873   1.342655468       279   0.58435907   1.128061669   1.111463384   1.18287234   1.133191489   1.473085106   1.082021277   1.006170213   2.055924822       280   0.981985137   0.862417805   0.922532197   1.173635437   0.969715781   1.055025939   0.964306301   1.068593979   3.269387173       281   1.082250133   1.004792182   2.144078679   1.584627667   1.820365801   1.118304543   1.003266076   2.923210916   3.73372093       282   0.900705523   0.946303827   0.960414277   1.210673317   1.225735661   1.274413965   1.245985037   1.126683292   2.055744681       283   0.874783814   1.300143331   1.561063716   1.080958583   1.698515238   1.549494949   1.217359845   1.453717693   2.139577128       284   0.736009098   0.980002843   0.900061603   0.803849001   0.74495083   1.039124458   0.766892249   0.813418632   2.540314704       285   1.66712766   1.126382979   1   0.918255964   0.576439566   0.576439566   0.66032992   0.576439566   1.66712766       286   1.271899225   1.101162791   1.166957364   0.94809531   0.923761825   1.186371225   1.109627156   1.231243993   1.862969973       287   1.004245661   1.075723548   1.005197959   1.153857565   0.831477223   0.751433143   0.809140326   0.625814587   1.868884868       288   0.910536655   1.104056877   1.213664286   1.359450663   1.109258818   1.805403403   1.446323199   0.966579344   1.805403403       289   1.048423862   0.935564574   0.980652694   0.850258626   0.898710142   0.982518169   0.866627382   0.863942906   2.26486698       290   1   1   1   0.517398509   0.743533094   0.692994569   1.031022738   0.776535027   5.887659574       291   1.201723264   1.077648251   1.143233654   0.973741442   1.00177205   1.184373741   0.859363673   0.790173178   1.867021277       292   0.772963128   0.971652159   0.87460025   1.265677813   1.169073337   1.521081193   1.211824901   1.089813427   2.334948374       293   0.724219044   0.909202108   0.897299586   1.125433526   1.33879255   1.354527938   1.086769428   1.28657675   2.012842012       294   0.796014266   0.844771603   0.873797631   0.742983745   1.124862593   0.915522827   0.769570124   1.010486687   2.051979526       295   1   1   1   0.660833333   0.489583333   0.489583333   0.489583333   0.489583333   1.564574468       296   1   1   1   0.656141792   0.551675568   0.551675568   0.551675568   0.551675568   2.137446809       297   1.547553191   1   1   1   1   1   1   1   1.836595745       298   0.967415431   1.117286691   1.069519666   1.206153634   1.148403084   1.570278084   1.283039648   1.329019824   2.436489362       299   0.866376639   0.978423324   1.30878621   1.360718434   1.406919149   2.072139303   1.615731913   1.313761589   3.832765957       300   1   1.266914894   1.10787234   0.78608463   1.163070748   0.78608463   1.582622512   1.146178291   1.582622512       301   0.847071309   0.640268863   0.879264163   0.561557142   0.735398729   0.673976501   1.004783281   0.916586945   7.937691573       302   0.738377393   0.859552025   0.932673525   1.694452738   1.38191915   1.5752075   1.387352959   1.424852212   2.739893617       303   0.648374627   0.877563935   0.899822536   1.054658326   1.028185429   1.332373998   1.094450919   1.005589515   2.266663125       304   1   1   1   0.583196469   0.546704989   0.783104085   0.532282899   0.65089304   1.227978723       305   1.516920396   1.226428298   1.100954619   0.874163451   0.801830382   0.749271501   1.216437795   1.157418216   1.8983562       306   1.09470128   1.406614509   1.251066856   0.767113863   1.287502315   0.696753195   1.078193221   0.821835887   1.497403983       307   1.463124504   1.026962728   1.141356067   0.94924916   0.952056834   0.905560046   0.736121155   0.759348279   2.605579263       308   1.622765957   1   1   0.946885035   0.939884393   0.882851638   1.018754014   0.803468208   7.322340426       309   0.834870849   0.915883932   0.911942301   0.950795084   1.417248802   0.96466912   1.063009513   1.165224637   1.424699056       310   1.115906085   0.878417108   0.887621252   0.97611523   0.834204449   0.887504558   0.981585025   0.868907257   1.960790415       311   1   1   1   1   1   1   1   1   2.115869757       312   0.772078827   1.053977838   0.928836839   0.793874602   0.924534944   0.856444082   0.809401171   0.841362188   2.349255319       313   1.517021277   1.30287234   1.281489362   1.013085106   1.193617021   1   1   1   1.517021277       314   1   1   1   0.508520422   0.508520422   0.508520422   0.508520422   0.508520422   1       315   1.502012953   1.182128479   1.430859443   0.967213115   0.900940098   0.864035428   0.797995494   0.7850439   1.602990033       316   1   1   1.061382979   1   1   1   1   1   1.947464923       317   1.089255319   1   1   1   1   1   1   1   1.298978644       318   1   1   1   0.62767094   0.62767094   0.62767094   0.62767094   0.62767094   1.848085106       319   1.073750127   1.365496099   1.721955047   0.87741338   1.90035469   1.468121538   1.553928678   1.961560638   2.147474858       320   1.800827182   1.857899742   1.590197588   0.6011213   0.412334299   0.209768613   0.437249964   0.341065235   2.011456777       321   2.802410519   3.130314098   2.002629657   1.104713506   0.991794489   1.02918551   0.886754627   0.933936314   3.130314098       322   1.017765957   1   1   0.62767094   0.62767094   0.62767094 0.62767094   0.62767094   1.846919302       323   1.193873269   1.002622744   0.986151909   1   1.123191489   1   1   1.034255319   2.316515945       324   1.028673871   1.034857075   1.244394619   0.872382213   0.942248704   1.288149619   0.864603332   1.188657178   2.252585097       325   1.263961187   0.866730682   0.999747309   0.822128702   0.765075645   0.876997656   0.855263158   0.783986789   2.180522826       326   1.018396434   1.233000565   1.147610975   0.885882745   1.31558176   0.858874994   1.051828254   0.879653844   1.573032344       327   1.441606413   0.909226658   0.879597611   0.915198131   0.915198131   0.915198131   0.915198131   1.066425859   1.528617021       328   1.397901857   1.534395781   2.070196056   1.226155733   1.50040181   1.379604957   1.247980375   1.283551157   2.356788133       329   1   1   1   1   1   1   1   1   2.1252123383       330   0.91811369   0.906009464   0.91267085   0.953153368   0.887496652   1.252299176   1.070359237   0.919670228   3.084566118       331   1   1   1   1   1.04212766   1   1   1   1.198344407       332   1.02271685   1.166264102   1.056685113   0.772114839   1.345323096   0.757535924   1.087443611   1.031966062   1.525632104       333   1.141808511   1   1   0.54184352   0.332484437   0.332484437   0.332484437   0.332484437   1.164468085       334   0.890270666   0.952542063   1.054773226   1   1.163510638   1   1   1   1.915106383       335   1   1.035   1.033297872   0.552071122   0.501807347   0.459163736   0.459163736   0.459163736   1.711688784       336   0.868522484   0.946181299   0.919985724   1.160187842   0.817462388   1.024089051   1.202104531   0.944603879   4.114859813       337   1.228994684   1.023059246   1.014892841   1.161584251   1.063516345   1.070017625   0.872767783   1.125070666   2.239192302       338   0.779467681   0.854195039   0.765522351   1.407078741   1.267912737   1.369742075   1.279377343   1.309601182   1.969918675       339   0.54605594   0.902394677   0.879105575   1.121718065   1.795194133   1.205526092   1.338047535   1.588293066   1.795194133       340   0.91445144   0.987551551   0.86244321   0.740083314   0.99710694   0.828665715   0.813208929   0.944476918   2.242061507       341   0.80786679   0.953809671   0.880296938   1.032677978   0.974055122   1.360220846   0.972035192   0.996139689   2.539557286       342   1.198477009   0.846919848   0.758322757   1.246484086   1.034830167   1.184513529   1.224401678   1.06591825   2.224170182       343   1.460210155   0.806304651   0.713718863 1   1   1   1   1   1.557351753       344   0.964386792   0.898820755   0.915978774   0.959186702   1.283689522   1.012540813   1.105224102   1.166295637   2.29122733       345   0.7148567   0.844718197   0.910898504   1.463194311   1.488966156   1.477993465   1.362780214   1.561931054   2.115540522       346   1.909893617   1.057872341   1.085212766   1.102978723   1   1.198297872   1   1.909893617       347   1.003190868   0.880814345   1.072356299   0.897957921   0.803960396   0.825618812   0.703155941   0.639665842   1.847992236       348   1.066872149   0.97531747   1.190062878   0.987956013   1.133317818   0.977075697   0.858943775   0.980954597   1.974879917       349   1.118065108   0.924438331   1.097294819   0.985637657   1.022469554   0.957472088   0.817535338   1.041933849   1.985113083       350   1.387174997   1.092738785   1.083093089   0.91083237   0.979242653   1.084304481   0.998754559   1.201405569   1.8       351   1.709242784   1.193580685   1.002460165   0.932237085   0.816364204   0.380335691   1.011416887   0.949504416   2.261063261       352   1   1   1   1   1.28606383   1.143297872   1   1   1.503085106   1.503085106       353   1   1   1.199787234   1.197776806   0.947542622   1.208767876   1.128395679   0.808030975   1.943297872       354   1.135135135   0.98540238   0.905960065   1.015951779   0.87506469   0.607385309   0.788304058   0.663429633   1.436937879       355   0.686164595   1.03285633   0.903833432   0.648813898   1.16167316   0.875455793   0.981213693   1.072663496   1.201913442       356   1   1   1   1   1   1   1   1   1.867021277       357   0.88360404   1.201796435   1.075254805   0.634219197   0.743879531   0.66615342   0.729713916   0.769008099   1.618989618       358   1   1   1   0.984644592   1.282818695   1.355910436   1.389804009   1.30135686   2.656492544       359   1   1   1   1   1   1   1   1   1.859574468       360   0.833154982   1.110526799   0.960834072   1.080841669   1.038022296   1.142849355   1.086974297   1.115211644   1.357630358       361   0.864465799   0.944717378   0.951492739   1.46970117   1.221017908   1.399318068   1.17026113   1.216443976   3.190718592       362   0.743494424   1.008700467   0.858024203   1.127217125   1.267787971   1.164424057   1.117940877   1.142813456   1.267787971       363   1   1   1   1   1   1   1   1   3.235425532       364   0.827611891   0.863374614   0.802143318   0.903736627   0.74858649   0.863259083   1.044384723   0.665874205   1.791358517       365   1.071489362   1.099042553   1.042659574   1.18287234   1.031914894   1.06   1.198297872   1.015531915   1.7483877097       366   1   1   1   1.020552344   1.25613359   1.433590238   1.15433526   1.573281952   2.259707193       367   0.711997477   0.78493178   0.768001195   1.040069409   0.90072593   1.357472618   1.191129648   1.173522669   2.114286534       368   1   1   1   1   1   1   1   1   2.150044085       369   0.759793671   0.938630977   0.862456434   0.972080028   0.994004038   1.205127159   1.191034609   1.072910081   4.27175051       370   1.57453322   1.356098643   1.302717492   1.062281282   1.093525553   1.24456942   1 .047538004   0.932242302   2.595615003       371   1.072189728   1.227946479   1.205352135   0.766533475   0.766533475   0.816602789   0.910462366   0.892848406   1.278343081       372   1.779403382   1.459908797   1.645259358   0.682563714   0.89822525   0.588695433   0.671124569   0.558541509   1.779403382       373   0.716081359   0.942637312   0.846042508   1.069335239    1.57692995   1.196568978   1.443084346   1.587651894   2.166276596       374   1.199953293   1.059831854   0.978701541   1.103592248   0.861430597   0.96608634   1.16925319   1.033480384   1.929473433       375   1.169293409   0.896377979   1.199151752   1.007031598   1.171384068   0.774032043   0.612527815   0.983622608   2.234498475       376   1.04996117   1.056777979   1.212787989   0.943159923   0.986062942   0.801734104   0.767951188   0.831021195   1.93501115       377   1.080735412   1.119765058   0.957877177   0.743297566   0.867850473   0.675339474   0.688380337   0.70999905   1.915590267       378   0.94493137   0.777034803   0.912809884   0.641521117   0.4714333   0.355468583   0.252481648   0.566878906   1       379   1   1   1   1   1   1   1   1   2.194099834       380   0.82255303   0.891229906   0.925853705   0.976414891   1.006929202   1.028233269   0.867398321   0.778738971   1.934825035       381   1   1   1   1       1   1   1   6.955212766       382   0.773165896   0.848446794   0.835228024   0.936721728   0.862092334   1.237018213   0.827869547   0.796272766   1.580106383       383   0.687036906   0.976642439   0.844047703   0.875885203   1.176108833   1.069139023   0.984811778   1.173686172   3.240602166       384   1   1   1   1   1.123191489   1   1   1.303404255   1.433004158       385   0.737497635   0.877719619   0.887368355   1.15385234   1.036244705   1.34389577   1.147954533   1.191491073   2.005849966       386   0.646593945   1.055209261   0.968239834   0.957858255   1.306042493   1.041890602   1.05952082   1.098648852   1.829488465       387   1.021246344   1.102353013   0.99348459   1.078375967   1.103036612   0.918838895   1.565018117   1.341280893   1.565592001       388   0.88612368   0.88612368   0.88612368   0.834412436   0.630571455   1.146757999   0.897657252   0.763723374   3.199516212       389   0.952863659   0.952863659   0.952863659   1   1.193617021   1   1   1.052978723   2.160636183       390   1.061572453   0.969276305   0.937760547   0.942207265   0.884240455   1.023151909   0.938725775   0.912556574   1.964051968       391   1   1   1   1   1   1   1   1   1.709526136       392   0.627583943   0.962766272   1.011369679   1.103367342   1.21882135   1.142357618   1.18998579   1.209433028   1.301790471       393   1.427132701   1.188684834   1.250592417   0.748587363   0.966903941   1.237543113   1.192338739   1.681147721   1.681147721       394   2.359800149   1.718992641   1.529066235   0.929832768   0.905430164   0.608505828   0.756207851   0.777764784   2.359800149       395   1   1   1   1   1   1   1   1   2.042765957       396   1   1   1   1   1   1   1   1   2.3688923       397   1.354947775   0.922840065   0.853589326   1.250662589   1.191641182   1.092558614   1.208766565   1.124974516   1.581131544       398   1.040114326   1.35270521   1.124103696   1.391611118   1.637274393   1.378513234   1.591743656   1.673059681   1.673059681       399   0.820279246   0.748987271   0.761345644   0.936766312   1.288493038   1.043987169   1.00996451   1.12465875   2.046190397       400   0.937188435   0.937188435   0.937188435   1.014633836   1.03906598   1.291467837   1.082712986   1.120188331   1.954148936       410   1   1   1   1   1   1   1   1.090319149   2.033727592       402   1   0.926659063   0.973127939   0.872309105   0.697975742   0.686815505   0.464098545   0.717216693   1       403   1   1   1   1   1   1   1   1   2.635141623       404   1.079420019   0.994480823   1.134705332   1   1.011595745   1.129468085   1   1.275851064   1.849148936       405   1.261271141   1.096042306   1.294779939   1.106045922   1.001480202   1.201325133   1.221889372   1.006061781   1.481142714       406   0.769099277   0.838461538   0.841880342   0.958205912   1.162895005   0.958205912   0.965749235   1.089398573   1.805638298       407   1   1   1   1   1.011595745   1   1   1.043617021   1.238758251       408   1   1   1   1   1   1   1   1   3.180443147       409   0.866921683   0.859707152   0.85909311   1.11047861   0.951699463   1.11047861   1.11047861   1.01601536   1.111936029       410   1   1   1.052446809   2.281276596   1.868404255   1.759148936   1.583510638   2.281276596       411   1.320499623   1.093816485   1.292636058   1.098297872   1   1.011914894   1   1.006170213   1.868606199       412   1   1   1   1   1   1   1   1   1.07477641       413   1   1   1   1   1   1   1   1   1.816303024       414   0.843774481   0.887145401   0.880545994   1.18847045   1.107964173   1.324549573   1.310059826   1.22198015   2.134586036       415   1.162773534   1.09509576   1.006310196   0.736155759   0.765694183   0.742342452   0.8100928   0.626978832   2.034803032       416   0.679366408   0.971530249   0.97494941   1.076604118   0.938927542   1.08995713   1.074003795   1.022559561   2.041276596       417   0.591414614   0.878754807   0.853861345   1.151216609   1.097328749   1.400952129   1.163118223   1.104601957   2.185061528       418   0.769526277   0.848212092   0.979920934   1.211142695   0.867879477   1.227743036   1.042455941   1.074792496   2.999187747       419   0.842346904   1.10073594   1.092836405   1.282111488   1.065310027   1.094356031   1.18505957   1.323419428   1.680040323                            AM       AM       AM       AM           1   min   1   min   1   min   1   min                       2   0.617720674   49   0.27783982   96   0.657987256   143   0.602525479           3   0.975882179   50   0.602448247   97   0.382084802   144   0.604985472           4   0.374159137   51   0.384386423   98   0.338017625   145   0.461479624           5   0.434105083   52   0.451640801   99   0.893026791   146   0.57766974           6   0.499975309   53   0.366885023   100   1   147   0.49659253           7   0.493257071   54   0.757270603   101   0.638500204   148   1           8   0.643130816   55   0.712224067   102   0.679807998   149   0.189006771           9   0.750773905   56   0.872632752   103   0.747921832   150   0.54598338           10   0.395613834   57   0.79459618   104   0.685190305   151   0.936161737           11   0.770591549   58   0.6006124   105   0.477289307   152   0.562493219           12   0.580658633   59   0.855115112   106   0.813003946   153   1           13   0.68949596   60   0.669166917   107   0.558380572   154   0.129959906           14   0.80129047   61   0.449564477   108   0.677042676   155   0.640803312           15   0.720711954   62   0.576620499   109   0.470047005   156   0.609360819           16   1   63   0.48107104   110   0.647026432   157   0.522579204           17   0.699456805   64   0.312010272   111   0.685770313   158   0.362416767           18   0.716511794   65   0.253919966   112   0.324518401   159   0.46555396           19   0.692804106   66   0.602417457   113   0.305283129   160   0.648650284           20   0.501467058   67   0.776800864   114   0.412230029   161   0.336123336           21   0.65582404   68   0.497450765   115   0.287437055   162   0.433025559           22   0.534945144   69   0.496881277   116   0.547455016   163   0.562022224           23   0.394132914   70   0.748288489   117   0.434842948   164   1           24   0.46631031171   71   0.365505203   118   0.387965671   165   0.861169898           25   0.448302175   72   0.399300334   119   0.49564269   166   0.545835251           26   0.773545221   73   0.395935179   120   0.767008097   167   0.429089161           27   0.736030759   74   0.756478352   121   1   168   0.863502705           28   0.551247861   75   0.670402612   122   0.753109815   169   0.390472833           29   0.689691105   76   0.670934199   123   0.401368018   170   0.744555027           30   1   77   0.743553235   124   1   171   0.897061304           31   0.529070749   78   0.781681497   125   0.384505256   172   0.988002181           32   0.52713633   79   0.751830581   126   0.474651586   173   0.520525452           33   0.228436886   80   0.499550979   127   0.215310085   174   0.447567811           34   0.669884546   81   0.515803336   128   0.723447772   175   0.877684407           35   0.320223641   82   1   129   0.963806008   176   0.669475875           36   0.894378651   83   0.707405178   130   0.677427259   177   0.419926014           37   0.555065854   84   0.587066076   131   0.309265271   178   0.735483302           38   0.358184612   85   0.293988866   132   0.558485656   179   0.378208739           39   1   86   0.591317099   133   0.370794052   180   0.494470842           40   0.53972894   87   0.723738504   134   0.214881701   181   0.450794404           41   0.716081359   88   0.404818059   135   0.826594261   182   0.220388258           42   0.503253302   89   0.5147789   136   0.446090585   183   0.540766551           43   0.55864057   90   0.556552798   137   0.485863441   184   0.798910963           44   0.709172555   91   0.755960401   138   0.515803336   185   0.425252618           45   0.930600931   92   0.700735655   139   0.654130134   186   0.864769686           46   0.585746033   93   0.786977492   140   0.266284397   187   0.529378221           47   0.806988969   94   0.799574065   141   0.4427342   188   0.29353339           48   0.194584748   95   0.693984525   142   0.444107358   189   0.35295324                                AM       AM       AM       AM       AM           1   min   1   min   1   min   1   min   1   min                       190   0.552892751   237   0.758157046   284   0.597972935   331   0.511926805   378   0.252481648           191   0.509159097   238   0.402978098   285   0.452363537   332   0.378309811   379   1           192   1   239   0.606356833   286   0.648215892   333   0.332484437   380   0.587932629           193   0.308267346   240   0.556938026   287   0.442389849   334   0.467057538   381   0.172698879           194   0.884632717   241   0.838807581   288   0.69163417   335   0.459163736   382   0.445683898           195   0.551287315   242   0.335910908   289   0.621766437   336   0.577861844   383   0.506510235           196   0.726254105   243   0.15105012   290   0.517398509   337   0.46292613   384   0.344836285           197   0.42560609   244   0.557855078   291   0.546225767   338   0.610106902   385   0.626518866           198   0.533936202   245   0.727936174   292   0.680963117   339   0.422928102   386   0.440755849           199   0.62401015   246   0.907906227   293   0.580263483   340   0.611884939   387   0.433022751           200   0.558559629   247   0.804729056   294   0.738023298   341   0.689945904   388   0.630571455           201   0.756478352   248   0.721080086   295   0.489583333   342   0.687276256   389   0.630957175           202   0.175626909   249   0.814464609   296   0.551675568   343   0.44078182   390   0.884240455           203   0.506079468   250   0.631698186   297   0.73151751   344   0.621230121   391   0.459208598           204   0.553722903   251   0.548784249   298   0.82673197   345   0.627326099   392   0.544781894           205   0.336076818   252   0.715100799   299   0.594965599   346   0.327937483   393   0.45538223           206   0.665387843   253   0.680674967   300   0.419221373   347   0.624469247   394   0.480167057           207   0.236429103   254   0.735996688   301   0.472338073   348   0.728834893   395   1           208   0.624969   255   0.525051826   302   0.738377393   349   0.817535338   396   1           209   0.683054298   256   0.497034721   303   0.648374627   350   0.645352892   397   0.516248974           210   0.390673704   257   0.717037778   304   0.532282899   351   0.358372728   398   0.549846837           211   0.741461145   258   0.202296504   305   0.444067596   352   0.304907717   399   0.65972613           212   0.557173245   259   0.436500972   306   0.315068933   353   0.75365   400   0.666051979           213   0.598293009   260   0.381803575   307   0.718215812   354   0.359324957   401   0.915109034           214   0.456645908   261   0.340460584   308   0.593494116   355   0.393581046   402   0.464098545           215   0.607909148   262   0.796473838   309   0.509321345   356   1   403   1           216   0.504449319   263   0.4361085   310   0.590813094   357   0.528711619   404   0.629888348           217   0.410367452   264   0.863172582   311   0.587056544   358   0.487956811   405   0.33895512           218   0.425422724   265   0.687687688   312   0.474594392   359   1   406   0.489437371           219   0.373219281   266   0.681356915   313   0.22932982   360   0.499916185   407   0.385313531           220   0.613000421   267   0.784313725   314   0.508520422   361   0.812983789   408   1           221   0.234759372   268   0.53946088   315   0.416349019   362   0.541568008   409   0.493831628           222   0.563481 597   269   0.348793238   316   0.586489527   363   1   0.52660431   410   0.560583312           223   0.404874069   270   0.942544871   317   0.451528634   364   0.52660431   411   0.680095244           224   1   271   0.080946558   318   0.62767094   365   0.543667149   412   0.538219296           225   0.324238557   272   0.382358758   319   0.496851701   366   0.441336067   413   0.8358868           226   0.212409869   273   0.658920874   320   0.163060943   367   0.489400859   414   0.754236235           227   0.210617132   274   0.541104912   321   0.101068748   368   1   415   0.626978832           228   0.547898493   275   0.123670821   322   0.475236278   369   0.713372638   416   0.679366408           229   0.791778976   276   0.782523969   323   0.525896759   370   0.582719279   417   0.591414614           230   0.634663426   277   0.625202102   324   0.682514738   371   0.347890452   418   0.644690782           231   0.378419422   278   0.527003795   325   0.347704715   372   0.44009551   419   0.550725293           232   0.600271657   279   0.58435907   326   0.415432023   373   0.388333471           233   0.884189508   280   0.862417805   327   0.468477448   374   0.272697033           234   0.44825685   281   0.681634155   328   0.484884222   375   0.406168567           235   0.582589908   282   0.754535238   329   0.802321611   376   0.767951188           236   0.550187401   283   0.381947134   330   0.7546261   377   0.625584235