Illness
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| Symptoms
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Adrenal Insufficiency | Fatigue | weakness | abdominal pain | nausea | low blood pressure | Sometimes | Chronic fatigue can be a prominent symptom |
Celiac Disease | Digestive problems | bloating | fatigue | skin rash | anemia | Sometimes | Diagnosis requires specific dietary testing. |
Crohn's Disease | Abdominal pain | diarrhea | weight loss | fatigue | Sometimes | Can mimic other digestive issues. | null |
Cushing's Syndrome | Weight gain | fatigue | muscle weakness | high blood pressure | Sometimes | Often misdiagnosed due to common symptoms. | null |
Diabetes (Type 2) | Increased thirst | frequent urination | fatigue | blurred vision | Sometimes | Early symptoms can be subtle. | null |
Endometriosis | Pelvic pain | heavy periods | infertility | Sometimes | Pain can be chronic and debilitating. | null | null |
Fibromyalgia | Widespread pain | fatigue | sleep disturbances | cognitive difficulties | Yes | Characterized by widespread musculoskeletal pain. | null |
Irritable Bowel Syndrome (IBS) | Abdominal pain | bloating | constipation | diarrhea | Sometimes | Symptoms can vary widely. | null |
Lupus | Fatigue | joint pain | skin rash | kidney problems | Sometimes | Can affect multiple organ systems. | null |
Lyme Disease | Fever | headache | fatigue | joint pain | rash (erythema migrans) | Sometimes | Early diagnosis is crucial for effective treatment. |
Multiple Sclerosis (MS) | Fatigue | numbness | tingling | vision problems | muscle weakness | Sometimes | Symptoms can relapse and remit. |
Myasthenia Gravis | Muscle weakness | fatigue | drooping eyelids | double vision | Sometimes | Symptoms worsen with activity and improve with rest. | null |
Polycystic Ovary Syndrome (PCOS) | Irregular periods | acne | excess hair growth | weight gain | Sometimes | Hormonal imbalances are key. | null |
Rheumatoid Arthritis | Joint pain | swelling | stiffness | fatigue | Yes | Autoimmune disease affecting the joints. | null |
Sarcoidosis | Fatigue | cough | shortness of breath | skin rashes | Sometimes | Can affect multiple organs | especially the lungs. |
Sjogren's Syndrome | Dry eyes | dry mouth | fatigue | joint pain | Sometimes | Autoimmune disease affecting exocrine glands. | null |
Thyroid Disorders (Hypothyroidism/Hyperthyroidism) | Fatigue | weight changes | mood changes | temperature sensitivity | Sometimes | Can mimic other conditions. | null |
Sleep Apnea | Loud snoring | daytime sleepiness | morning headaches | Sometimes | Diagnosis requires a sleep study. | null | null |
Mast Cell Activation Syndrome (MCAS) | Allergic-type reactions | hives | itching | flushing | digestive problems | Sometimes | Difficult to diagnose and often mistaken for allergies. |
Small Intestinal Bacterial Overgrowth (SIBO) | Bloating | gas | abdominal pain | diarrhea | Sometimes | Diagnosis requires breath testing. | null |
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) | Pelvic pain | frequent urination | urgency | Sometimes | Chronic pain in the bladder and pelvic region. | null | null |
Complex Regional Pain Syndrome (CRPS) | Severe burning pain | swelling | changes in skin color and temperature | Yes | Chronic pain condition often triggered by an injury. | null | null |
Postural Orthostatic Tachycardia Syndrome (POTS) | Dizziness | lightheadedness | fainting | rapid heart rate upon standing | Sometimes | Symptoms often worsen with changes in posture. | null |
Ehlers-Danlos Syndromes (EDS) | Joint hypermobility | skin hyperextensibility | fragile skin | Sometimes | Genetic connective tissue disorder. | null | null |
Wilson's Disease | Liver problems | neurological symptoms | psychiatric symptoms | Sometimes | Genetic disorder affecting copper metabolism. | null | null |
Autoimmune Hepatitis | Fatigue | jaundice | abdominal pain | liver inflammation | Sometimes | Body attacks its own liver cells. | null |
Primary Biliary Cholangitis (PBC) | Fatigue | itching | jaundice | abdominal pain | Sometimes | Autoimmune disease affecting the bile ducts. | null |
Non-alcoholic Fatty Liver Disease (NAFLD) | Fatigue | abdominal pain | elevated liver enzymes | Sometimes | Can lead to cirrhosis if left untreated. | null | null |
Hemochromatosis | Fatigue | joint pain | abdominal pain | skin discoloration | Sometimes | Genetic disorder causing iron overload. | null |
Alpha-1 Antitrypsin Deficiency | Shortness of breath | wheezing | chronic cough | liver problems | Sometimes | Genetic disorder affecting the lungs and liver. | null |
Porphyria | Abdominal pain | neurological symptoms | skin sensitivity to light | Sometimes | Group of genetic disorders affecting heme production. | null | null |
Amyloidosis | Fatigue | swelling | numbness | tingling | organ damage | Sometimes | Rare disease characterized by protein deposits in tissues. |
Vasculitis | Fatigue | fever | weight loss | rash | organ damage | Sometimes | Inflammation of blood vessels. |
Systemic Sclerosis (Scleroderma) | Skin thickening | joint pain | Raynaud's phenomenon | organ damage | Sometimes | Connective tissue disorder affecting the skin and internal organs. | null |
Mixed Connective Tissue Disease (MCTD) | Symptoms overlapping with lupus | scleroderma | and polymyositis | Sometimes | Autoimmune disease with features of multiple conditions. | null | null |
Polymyositis | Muscle weakness | fatigue | muscle pain | Sometimes | Autoimmune disease causing muscle inflammation. | null | null |
Dermatomyositis | Muscle weakness | skin rash | muscle pain | Sometimes | Autoimmune disease affecting skin and muscles. | null | null |
Giant Cell Arteritis | Headache | jaw pain | vision changes | fever | Sometimes | Inflammation of arteries in the head and neck. | null |
Takayasu Arteritis | Fatigue | fever | weight loss | decreased pulses in the arms and legs | Sometimes | Inflammation of large arteries. | null |
Behcet's Disease | Mouth sores | genital sores | eye inflammation | skin lesions | Sometimes | Chronic inflammatory disorder affecting multiple systems. | null |
IgG4-Related Disease | Masses or swelling in various organs | fatigue | weight loss | Sometimes | Chronic inflammatory condition characterized by IgG4-producing plasma cells. | null | null |
Relapsing Polychondritis | Inflammation of cartilage in various parts of the body | pain | swelling | Sometimes | Rare disease affecting cartilage. | null | null |
Granulomatosis with Polyangiitis (GPA) | Respiratory problems | kidney problems | skin lesions | Sometimes | Rare autoimmune disease affecting blood vessels and tissues. | null | null |
Eosinophilic Granulomatosis with Polyangiitis (EGPA) | Asthma | sinusitis | nerve damage | skin lesions | Sometimes | Rare autoimmune disease affecting blood vessels and tissues. | null |
Microscopic Polyangiitis (MPA) | Kidney problems | skin lesions | nerve damage | Sometimes | Rare autoimmune disease affecting small blood vessels. | null | null |
Primary Sclerosing Cholangitis (PSC) | Fatigue | itching | jaundice | abdominal pain | Sometimes | Chronic liver disease affecting the bile ducts. | null |
Idiopathic Pulmonary Fibrosis (IPF) | Shortness of breath | dry cough | fatigue | Sometimes | Chronic lung disease causing scarring of lung tissue. | null | null |
Pulmonary Hypertension | Shortness of breath | fatigue | chest pain | dizziness | Sometimes | High blood pressure in the arteries of the lungs. | null |
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