Illness
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Symptoms
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Adrenal Insufficiency
Fatigue
weakness
abdominal pain
nausea
low blood pressure
Sometimes
Chronic fatigue can be a prominent symptom
Celiac Disease
Digestive problems
bloating
fatigue
skin rash
anemia
Sometimes
Diagnosis requires specific dietary testing.
Crohn's Disease
Abdominal pain
diarrhea
weight loss
fatigue
Sometimes
Can mimic other digestive issues.
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Cushing's Syndrome
Weight gain
fatigue
muscle weakness
high blood pressure
Sometimes
Often misdiagnosed due to common symptoms.
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Diabetes (Type 2)
Increased thirst
frequent urination
fatigue
blurred vision
Sometimes
Early symptoms can be subtle.
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Endometriosis
Pelvic pain
heavy periods
infertility
Sometimes
Pain can be chronic and debilitating.
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Fibromyalgia
Widespread pain
fatigue
sleep disturbances
cognitive difficulties
Yes
Characterized by widespread musculoskeletal pain.
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Irritable Bowel Syndrome (IBS)
Abdominal pain
bloating
constipation
diarrhea
Sometimes
Symptoms can vary widely.
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Lupus
Fatigue
joint pain
skin rash
kidney problems
Sometimes
Can affect multiple organ systems.
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Lyme Disease
Fever
headache
fatigue
joint pain
rash (erythema migrans)
Sometimes
Early diagnosis is crucial for effective treatment.
Multiple Sclerosis (MS)
Fatigue
numbness
tingling
vision problems
muscle weakness
Sometimes
Symptoms can relapse and remit.
Myasthenia Gravis
Muscle weakness
fatigue
drooping eyelids
double vision
Sometimes
Symptoms worsen with activity and improve with rest.
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Polycystic Ovary Syndrome (PCOS)
Irregular periods
acne
excess hair growth
weight gain
Sometimes
Hormonal imbalances are key.
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Rheumatoid Arthritis
Joint pain
swelling
stiffness
fatigue
Yes
Autoimmune disease affecting the joints.
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Sarcoidosis
Fatigue
cough
shortness of breath
skin rashes
Sometimes
Can affect multiple organs
especially the lungs.
Sjogren's Syndrome
Dry eyes
dry mouth
fatigue
joint pain
Sometimes
Autoimmune disease affecting exocrine glands.
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Thyroid Disorders (Hypothyroidism/Hyperthyroidism)
Fatigue
weight changes
mood changes
temperature sensitivity
Sometimes
Can mimic other conditions.
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Sleep Apnea
Loud snoring
daytime sleepiness
morning headaches
Sometimes
Diagnosis requires a sleep study.
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Mast Cell Activation Syndrome (MCAS)
Allergic-type reactions
hives
itching
flushing
digestive problems
Sometimes
Difficult to diagnose and often mistaken for allergies.
Small Intestinal Bacterial Overgrowth (SIBO)
Bloating
gas
abdominal pain
diarrhea
Sometimes
Diagnosis requires breath testing.
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Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)
Pelvic pain
frequent urination
urgency
Sometimes
Chronic pain in the bladder and pelvic region.
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Complex Regional Pain Syndrome (CRPS)
Severe burning pain
swelling
changes in skin color and temperature
Yes
Chronic pain condition often triggered by an injury.
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Postural Orthostatic Tachycardia Syndrome (POTS)
Dizziness
lightheadedness
fainting
rapid heart rate upon standing
Sometimes
Symptoms often worsen with changes in posture.
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Ehlers-Danlos Syndromes (EDS)
Joint hypermobility
skin hyperextensibility
fragile skin
Sometimes
Genetic connective tissue disorder.
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Wilson's Disease
Liver problems
neurological symptoms
psychiatric symptoms
Sometimes
Genetic disorder affecting copper metabolism.
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Autoimmune Hepatitis
Fatigue
jaundice
abdominal pain
liver inflammation
Sometimes
Body attacks its own liver cells.
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Primary Biliary Cholangitis (PBC)
Fatigue
itching
jaundice
abdominal pain
Sometimes
Autoimmune disease affecting the bile ducts.
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Non-alcoholic Fatty Liver Disease (NAFLD)
Fatigue
abdominal pain
elevated liver enzymes
Sometimes
Can lead to cirrhosis if left untreated.
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Hemochromatosis
Fatigue
joint pain
abdominal pain
skin discoloration
Sometimes
Genetic disorder causing iron overload.
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Alpha-1 Antitrypsin Deficiency
Shortness of breath
wheezing
chronic cough
liver problems
Sometimes
Genetic disorder affecting the lungs and liver.
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Porphyria
Abdominal pain
neurological symptoms
skin sensitivity to light
Sometimes
Group of genetic disorders affecting heme production.
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Amyloidosis
Fatigue
swelling
numbness
tingling
organ damage
Sometimes
Rare disease characterized by protein deposits in tissues.
Vasculitis
Fatigue
fever
weight loss
rash
organ damage
Sometimes
Inflammation of blood vessels.
Systemic Sclerosis (Scleroderma)
Skin thickening
joint pain
Raynaud's phenomenon
organ damage
Sometimes
Connective tissue disorder affecting the skin and internal organs.
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Mixed Connective Tissue Disease (MCTD)
Symptoms overlapping with lupus
scleroderma
and polymyositis
Sometimes
Autoimmune disease with features of multiple conditions.
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Polymyositis
Muscle weakness
fatigue
muscle pain
Sometimes
Autoimmune disease causing muscle inflammation.
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Dermatomyositis
Muscle weakness
skin rash
muscle pain
Sometimes
Autoimmune disease affecting skin and muscles.
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Giant Cell Arteritis
Headache
jaw pain
vision changes
fever
Sometimes
Inflammation of arteries in the head and neck.
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Takayasu Arteritis
Fatigue
fever
weight loss
decreased pulses in the arms and legs
Sometimes
Inflammation of large arteries.
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Behcet's Disease
Mouth sores
genital sores
eye inflammation
skin lesions
Sometimes
Chronic inflammatory disorder affecting multiple systems.
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IgG4-Related Disease
Masses or swelling in various organs
fatigue
weight loss
Sometimes
Chronic inflammatory condition characterized by IgG4-producing plasma cells.
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Relapsing Polychondritis
Inflammation of cartilage in various parts of the body
pain
swelling
Sometimes
Rare disease affecting cartilage.
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Granulomatosis with Polyangiitis (GPA)
Respiratory problems
kidney problems
skin lesions
Sometimes
Rare autoimmune disease affecting blood vessels and tissues.
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Eosinophilic Granulomatosis with Polyangiitis (EGPA)
Asthma
sinusitis
nerve damage
skin lesions
Sometimes
Rare autoimmune disease affecting blood vessels and tissues.
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Microscopic Polyangiitis (MPA)
Kidney problems
skin lesions
nerve damage
Sometimes
Rare autoimmune disease affecting small blood vessels.
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Primary Sclerosing Cholangitis (PSC)
Fatigue
itching
jaundice
abdominal pain
Sometimes
Chronic liver disease affecting the bile ducts.
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Idiopathic Pulmonary Fibrosis (IPF)
Shortness of breath
dry cough
fatigue
Sometimes
Chronic lung disease causing scarring of lung tissue.
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Pulmonary Hypertension
Shortness of breath
fatigue
chest pain
dizziness
Sometimes
High blood pressure in the arteries of the lungs.
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