Patent Application: US-201313972830-A

Abstract:
a solid synthetic bar cleanser for cleaning a person &# 39 ; s skin has an acidic ph of about 5 . 5 . the syndet from which the solid bar cleanser is formed comprises as a natural foaming agent quillaja bark extract in an amount of 0 . 01 % to about 1 %. the syndet further comprises from 0 . 5 % to about 2 % of bergaptene - free essential lemon oil , from 0 . 0001 % to about 1 % thymol , and 0 . 01 % to about 1 % of lavender oil for odor and antimicrobial purposes .

Description:
exemplary embodiments of the present invention result in very nonirritating , physiologically perfect , skin cleaner . because it does not disturb the ph of the skin and also does not injure the “ barrier function ” of the skin , it renders the skin more physiologically impervious to the various toxins that skin is exposed to daily . these include environmental pollutants and also cosmetic products that are toxic to the skin . a syndrome of skin toxicity , largely due to soap toxicity , includes a slight redness , and a slight swelling of the skin , and enlarged , visible , pores . so many people have this problem , for so many years , that they think that that appearance is the innate characteristic of their skin . but when their exposure to skin cleansing products containing skin irritants is eliminated , and the cleansers of the present invention are initiated in a daily regimen , their skin is permitted to “ detox ” and its appearance and actual health improves . exemplary embodiments of the present invention are beneficial when used alone , but are even more effective and have an overall synergistic effect when used as part of the system of skin rejuvenators which are the subjects of my co - pending patent applications . by using a more physiologic cleaner which , like the present invention , has the correct ph and without irritants , a patient achieves clean , healthy , ph - balanced skin which will allow for better penetration and utilization of the active agents in this and the other components of my skin rejuvenation system . irritants include the majority of commonly used surfactants , including sls and sodium laureth sulfate and dozens more . other irritants include various fragrances and preservatives which are common causes of contact dermatitis . these substances are avoided by formulations designed according to the teachings of the present invention . elimination of preservatives is a notable advantage of this invention . the exemplary embodiment was designed as a solid , which does not promote the growth of bacteria . lemon and thyme oils are natural antibacterials and antifungals that further suppress the growth of bacteria and fungus in bar cleansers of the present invention . exemplary embodiments of the disclosed invention are syndet formulations that perform well . specifically , they provide a skin cleansing bar which creates froth volume that consumers associate with good cleansing , and at a ph in a range of from 5 . 3 to about 5 . 8 , preferably of 5 . 5 . typical syndets perform abysmally , creating a paltry amount of lather and a perception by a typical user that the cleaning ability is similarly minimal . furthermore , the formulations of the present invention produce a “ synthetic ” cleanser for skin that is substantially free of skin irritants that can cause local inflammation and skin irritation , without actually promoting the growth of bacteria and fungi . the non - inflammatory ingredients of the present formulations provide a soothing experience with a pleasant texture and color . the formulations have a pleasing scent provided by ingredients that also have anti - oxidant , antifungal and antibacterial properties . the skin cleanser of the present invention is a vegetable - based syndet bar . there are no animal products used in the creation of the skin cleanser of the present invention . the ph is the same as normal skin — i . e . in a range of from ph 5 . 3 to about ph 5 . 8 but preferably about ph 5 . 5 . as a synthetic cleansing bar , the base has been formulated to meet this precise ph . the skin cleanser of the present invention contains a variety of unique ingredients that improve the performance of the bar . of note is that this bar is free of preservatives . the following listing of ingredients are provided as an exemplary , but non - limiting , embodiment of the present invention which is then formed into bars , as described hereinbelow . elimination of preservatives is a notable advantage of this invention . the exemplary embodiment cleansers are designed as a solid , which do not promote the growth of bacteria . lemon and thyme oils are natural antibacterials that further suppress the growth of bacteria in the cleansers of the present invention ( see references below in ingredient section ). “ performance ” in bar skin cleaners is a function of skin cleaning ability , lather , “ slip ”, and bar integrity . the present invention substituted common toxic surfactants with the coconut derived sodium cocoyl isethionate , cocamidopropyl hydroxysultaine , and sodium isethionate , substances that are milder skin cleaners 14 that help remove excess oil and dirt from the skin . to accomplish the characteristic look , feel , smell , and performance of the present invention , a specific mixture of ingredients was used . quillaja saponaria bark extract , also known as soap bark , is a key ingredient in the present invention . quillaja is a food additive that creates foam for carbonated drinks such as root beer and is the substance that gives a solid cleanser bar formulated according to the present invention its unique frothiness . quillaja extract is purified extract of outer cambium layer of quillaja saponaria molina tree and contains natural nonionic surfactants called saponins that stabilize foams and emulsions . 15 saponins are detergent - like substances showing antibacterial , antiviral , antitrichomonal , and antifungal activity . the antiviral properties have been demonstrated against rotavirus , vaccinia virus , herpes simplex virus type 1 , varicella zoster virus , human immunodeficiency viruses 1 and 2 ( hiv - 1 , hiv - 2 ) and reovirus . quillaja inhibits infection from host cells by preventing attachment and replication of virus 16 17 18 . in addition , it inhibits fungal growth , 19 20 and has anti - staphylococcal properties . 21 quillaja saponaria has anti - trichomonas vaginalis activity and inhibits mosquito larval development . 22 23 it is also anti - inflammatory , 24 and an antioxidant 25 the combination of frothing ability as well as antibacterial , antiviral , anti trichomonal , and antifungal properties make quillaja an ideal agent for solid cleanser bars formulated according to the present invention , providing performance enhancement as well as antimicrobial qualities . other naturally occurring frothing agents include yucca saponin , which also is included in this patent and imparts similar qualities to soap and foods . ground oats — this substance imparts a homoegenous white color and “ body ” to the syndet and gives it a soothing feel . ground oats have moisurization qualities , 26 and are anti - inflammatory and antihistaminic . the avenanthramides , a component of whole oat grain , are responsible for many of these effects . avenanthramides inhibit the activity of nuclear factor kappab and the release of proinflammatory cytokines and histamine , mechanisms in the pathophysiology of inflammatory dermatoses . natural colloidal oatmeal helps restore the skin barrier and can improve atopic dermatitis and other conditions . 27 28 avenanthramides are phenolic compounds present in oats at approximately 300 parts per million ( ppm ) and exhibit anti - oxidant 29 and potent anti - inflammatory activity that are responsible for the anti - irritant effects of oats . 30 glycerin — this humectant provides the physical sensation of “ slip ”, as opposed to “ friction ” when the bar is moved against the skin . the right amount of “ slip ” is necessary for an aesthetically pleasing experience . in addition , glycerin protects against irritants , accelerates recovery of irritated skin , increases water content of skin 31 32 , and decreases symptoms of atopic dermatitis 33 . the diverse actions of the polyol glycerol on the epidermis include improvement of stratum corneum hydration , skin barrier function and skin mechanical properties , inhibition of the stratum corneum lipid phase transition , protection against irritating stimuli , enhancement of desmosomal degradation , and acceleration of wound - healing processes . additionally , an antimicrobial effect has been demonstrated . topical application of glycerol - containing products improves skin properties in diseases characterized by xerosis and impaired epidermal barrier function , such as atopic dermatitis . the increase of epidermal hydration by glycerol is critical in skin conditions aggravated by dry and cold environmental conditions , e . g . winter xerosis . beeswax — soaps and syndets are mixtures of a variety of chemicals and will separate spontaneously as they age , causing a physical crumbling of the bar . to maintain bar integrity , most soaps contain petrolatum , an oil based product and suspected carcinogen 34 35 . the formulation for syndets of the present invention substitutes natural beeswax to maintain the integrity of the bar . beeswax has a pleasant natural scent and is so nontoxic that it is actually edible , comprising the delicacy known as honeycomb . thymus vulgaris flower / leaf oil ( thyme )— a natural antioxidant 36 37 which also has antibacterial and antifungal properties . in concentrations of 3 %, thyme essential oil healed fungal infections . 38 thyme inhibits the growth of staphylococcus , enterococcus , escherichia , and pseudomonas bacteria , including multidrug resistant varieties . 39 it has also been shown to have antimicrobial properties against klebsiella and step agalactiae bacteria . the antimicrobial activity of thyme is not trivial — in fact it is stronger than that of the commonly used synthetic bht . 40 thyme has also been shown to cure leishmaniasis . 41 thyme oil , particularly pungent , is an important component in the fragrance mixture of the exemplary embodiment . bergaptene - free essential lemon oil — this aromatherapy agent imparts part of the unique fragrance , along with lavender and thyme . common lemon oil is a photosensitizer , 42 but bergaptene - free lemon oil , has all or substantially of the photosensitizing agent , bergaptene , removed , thereby eliminating most of the photosensitizing effect of lemon oil . lemon oil is also a natural antibacterial . staphylococcus aureus , pseudomonas aeruginosa , oenococcus and lactobacillus bacteria , 43 44 45 candida and aspergillis fungus are all also killed by lemon and lavender oils . 46 interestingly , lemon essential oil and thyme essential oil naturally repel mosquitos , probably because they are toxic to mosquito larvae . 47 essential lemon oil enhances the penetration of vitamins e , a ( retinyl acetate ), and c ( ascorbic acid ), important components of the inventor &# 39 ; s patent pending day cream and evening serum regimens . 48 essential lemon oil has strong antioxidant activity and , in particular , significantly increases the antioxidative potential of the skin . 49 50 essential lavender oil — one of only two aromatherapy agents ( the other being lemon oil ) that have proven ability to lower blood pressure and heart rate . 51 52 these essential oils are natural mood elevators , and are released into the air during use of the product . both lemon and lavender oils have been shown to improve cognitive function in alzheimer &# 39 ; s dementia patients . 53 lavender and lemon oils have anxiolytic and antidepressant effects by suppressing dopamine activity in the brain . 54 the exemplary embodiments of the present invention take advantage of the natural antibacterial and antifungal properties of lavender , lemon , and thyme oils , obviating the need for synthetic or other potentially skin - irritating or sensitizing preservatives . the unique fragrance of syndets formulated according to the present invention is a result of the blend of lemon , lavender , and thyme oils . the listed raw materials are blended together , checked to ensure the ph level is between 5 . 3 and 5 . 8 and preferably at ph 5 . 5 , in a mix tank under proprietary conditions . the resultant molten synthetic batch is filtered and pumped onto a roll , to convert the molten material to a thin solid , the syndet . the solid syndet is scraped from the roll and conveyed to a pelletizer . the pelletizer converts the syndet into a noodle form that is placed in a super sack for storage and handling . further processing is done by placing the syndet noodles into an amalgamator and mixing with final product ingredients such as fragrances or other additives . the resultant mass is milled and extruded into billets . the billets are then pressed into finished bars and packaged as the finished product . the non - irritant and non - sensitizing status of the cleanser of the exemplary embodiment was appraised using a repeat insult patch test . when the exemplary embodiment cleanser having the formulation described hereinabove was applied to 50 human subjects under semi - occlusion at a 10 % dilution in distilled water , in accordance with the industry reference appraisal of the safety of chemicals in food , drugs and cosmetics , published by the association of food and drug officials of the united states , 1965 ( modified ), no irritation or sensitization was observed in any of the subjects . each subject had 9 discrete 24 - hour exposures over a period of three weeks and no reactions or adverse events were observed . 1 acta derm venereol . 2013 may ; 93 ( 3 ): 261 - 7 . skin ph : from basic science to basic skin care . alism , yosipovitch g . 2 int j dermatol . 2002 august ; 41 ( 8 ): 494 - 9 . correlation between ph and irritant effect of cleansers marketed for dry skin . baranda l , gonzalez - amaro r , torres - 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