Patent Application: US-201313815286-A

Abstract:
the invention is crustacean hemolymph as a utility for the pharmaceutical and / or cosmetic treatment of viral and other neoplastic or pre - neoplastic mammalian tissue lesions . the method comprises topically administering to mammalian tissue a formula that is made from lobster hemolymph — neat ; or lobster hemolymph extracts ; or lobster hemolyph in combination with certain carriers , binders ; or as an adjuvant . the hemolymph may be from various species of lobster , homarus americanus in particular .

Description:
hemolymph from the lobster , particularly but not exclusively homarus americanus is utilized ( neat or with active fragments extracted or in compounds ) for the treatment in mammals of viral ( such as molluscum contagiosum , verruca vulgaris — commonly known as warts , among others ) and tissue neoplastic or pre - neoplastic lesions ( such as ephelides , solar lentigos — commonly known as sun spots , and actinic keratosis , among others ). by “ neat ” it is meant the hemolymph is in the form collected from the lobster , and by “ active fragments ” it is meant a fragment or fragments of the hemolymph that stimulate an immune response . typically , the mammal treated will be human . the treatment can also be applied to other mammals such as those in the bovine , porcine , ovine , equine , canine , or feline families , among others . preparation may involve partial drying of whole hemolymph or plasma to produce a slurry . the hemolymph can be incorporated into a cosmetic or pharmaceutical compound together with a suitable carrier or carriers i . e . carageenans , starches , gelatins , vitamins , aloe , proteins , glycerins , parabens , crustacean shell powder , mineral oils , and plant oils . in non - clinical testing , various skin lesions were exposed to lobster hemolymph neat or absorbed into fibrous absorptive material attached to adhesive tape . it was found that the topical hemolymph treatment had an atrophic and / or fading effect on said lesions . it is not known how the hemolymph interacts with tissue to produce his effect . however , it is known that the immune system of arthropods resides in the hemolymph and the hemocytes within the hemolymph play a role , which may be part of the explanation . hemolymph is extracted using a variety of methods , including but not limited to : 1 . 1 . needle and syringe to pierce the pericardial membrane to draw directly from circulatory system ; 1 . 2 . using a knife or scalpel to lance the soft tissue allowing blood flow to a catch basin or bottle ; 1 . 3 . by separating the thorax ( body ) from the abdomen ( tail ) thus opening the circulatory system at the pericardium and draining the hemolymph into a catch basin or bottle . treatment of molluscum contagiosum with homarus americanus hemolymph — neat . anecdotal study a juvenile female human suffering from molluscum contagiosum lesions treated with neat hemolymph (“ neat ” is defined as that form of hemolymph extracted directly from the lobster ) in a dose 0 . 5 ml for 5 days . the treated lesion atrophied over the course of the treatment period , whereas , adjacent lesions remained unchanged during that same time period . treatment of an actinic lesion with homarus americanus hemolymph — neat . anecdotal study an adult male human with a facial actinic lesion was treated with neat hemolymph in a dose of 0 . 5 ml for approximately 10 days . before the hemolymph was administered the lesion was prepared by lightly abrading the affected epidermis . the lesion initially blanched and then and appeared to atrophy over the course of the treatment . treatment of verruca vulgaris with homarus americanus hemolymph — neat . anecdotal study an adult male human with a manifestation of the virus verruca vulgaris ( a common wart ) topically treated the lesion with neat hemolymph in a dose of 0 . 5 ml sporadically over two weeks . over the course of treatment the wart softened and atrophied . treatment of herpes zoster with homarus americanus hemolymph — neat . anecdotal study an adult female exhibiting a rash from the virus herpes zoster ( shingles ) topically treated the rash with neat hemolymph in a dose of approximately 0 . 5 ml and noticed considerable reduction is redness , itchiness and swelling in a 12 hour period . cuthbertson , adrian — inventor . 2011 . original assignee : marine biotechnology australia pty ltd . current u . s . classification : 424 / 208 . 1 ; 424 / 204 . 1 ; 424 / 209 . 1 ; 424 / 229 . 1 ; 424 / 230 . 1 ; 424 / 231 . 1 ; 514 / 3 . 7 ; 514 / 3 . 8 ; 514 / 4 . 2 dolashka p , velkova l , iliev i , beck a , dolashki a , yossifova l , toshkova r , voelter w , zacharieva s . 2003 . antitumor activity of glycosylated molluscan hemocyanins via guerin ascites tumor . eur urol . ; 37 suppl 3 : 34 - 40 . 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( key laboratory of marine biogenetic resources , the third institute of oceanography , state oceanic administration , 361005 , xiamen , pr china .)