Opinion ID: 809417
Heading Depth: 4
Heading Rank: 3

Heading: The Henry Ford Patient Records

Text: Appellants present two patient records from the Henry Ford Clinic in Detroit, Michigan, showing doctors prescribed a daily dose of naproxen as a prophylactic treatment, and sumatriptan for treating acute migraines. Appellants argue that because the two agents would be working in the body at the same time, even if taken separately, they are concomitantly administered. Additionally, Appellants contend that a person of ordinary skill in the art would expect a daily dose of naproxen to have the same effectiveness as a single dose of naproxen taken when needed because concentration of the drug in the blood would be the same or higher. Therefore, Appellants assert that when sumatriptan is taken in addition to a daily dose of naproxen the combination of the two drugs would have the same effect as when the two drugs are given simultaneously. Dr. Ramadan, who treated the patients at the clinic, testified that he did not recall ever prescribing or giving a patient sumatriptan and naproxen simultaneously. Furthermore, the Henry Ford Records do not suggest that it produced longer lasting efficacy or reduced migraine 19 POZEN INC v. PAR PHARMA relapse. At least one of the patients’ prescriptions was soon altered to sumatriptan and an antidepressant, suggesting the combination of sumatriptan and naproxen did not work to relieve migraine symptoms. Accordingly, the district court did not err in its determination of the scope of the teachings of the Henry Ford Records; we hold that the patient records do not render the ’499 and ’458 patents obvious.