Opinion ID: 2792379
Heading Depth: 3
Heading Rank: 1

Heading: A method of treating an ocular infection, com-

Text: prising topically administering to an eye of an animal in need of such treatment an ocular infection-treating amount of azithromycin. The ISV patents disclose various formulations and methods of using topical azithromycin as a gel eyedrop for treating eye infections. Claim 1 of the ’113 patent; claim 16 of the ’443 patent; and claim 1 of the ’893 patent are representative and recite: 1. A process for treating an eye, which comprises: topically applying an aqueous polymeric suspen- sion of an azalide antibiotic, wherein said suspension comprises water, 0.01% to 1.0% of an azalide antibiotic, and 0.1 to 10% of a polymeric suspend- ing agent. ’113 patent claim 1; 16. A topical ophthalmic composition comprising an aqueous polymeric suspension comprising wa- ter, 0.01% to 1.0% of an azalide antibiotic and 0.1 to 10% of a polymeric suspending agent, wherein said topical ophthalmic composition has an osmotic pressure of from 10 to 400 mOsM and wherein said composition does not contain constituents that are physiologically or ophthalmically harmful to the eye. 4 INSITE VISION INCORPORATED v. SANDOZ, INC. ’443 patent claim 16; 1. A composition comprising water, a polymeric suspending agent and an azalide antibiotic, wherein said composition has a pH of about 6.0 to 6.6. ’893 patent claim 1.